# emapper version: emapper-hotfix-numpy-45-g001c4bf emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share_mix/Bin_all/emapper//MAG.T2.48/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share_mix/Bin_all/Bin_prokka//MAG.T2.48/MAG.T2.48.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share_mix/Bin_all/emapper//MAG.T2.48/MAG.T2.48 --usemem --override # time: Sat Jun 6 08:11:29 2026 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. MAG.T2.48_00001 110319.CF8_1016 1.8e-38 166.8 Propionibacteriales Bacteria 2HY6Q@201174,4DT1Q@85009,COG1524@1,COG1524@2 NA|NA|NA S Metalloenzyme superfamily MAG.T2.48_00004 926549.KI421517_gene109 2.8e-87 329.3 Cytophagia ko:K08369 ko00000,ko02000 2.A.1 Bacteria 47KKT@768503,4NEQU@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.48_00005 530564.Psta_1355 5.6e-46 191.8 Planctomycetes Bacteria 2IXGB@203682,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family MAG.T2.48_00006 478741.JAFS01000001_gene1690 1.3e-78 300.8 unclassified Verrucomicrobia Bacteria 37G6V@326457,46U84@74201,COG3011@1,COG3011@2 NA|NA|NA S Lipase maturation factor MAG.T2.48_00007 748247.AZKH_0082 1.3e-45 191.4 Proteobacteria Bacteria 1R56X@1224,COG2234@1,COG2234@2 NA|NA|NA S Peptidase family M28 MAG.T2.48_00008 649638.Trad_2420 5e-144 518.1 Deinococcus-Thermus ggt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 1WI9V@1297,COG0405@1,COG0405@2 NA|NA|NA E PFAM Gamma-glutamyltranspeptidase MAG.T2.48_00010 452637.Oter_1654 8.6e-15 88.6 Verrucomicrobia sprB 3.4.21.80,3.4.21.81,3.4.21.82 ko:K18544,ko:K18545,ko:K18546,ko:K18547,ko:K18548 ko00000,ko01000,ko01002 Bacteria 46WAW@74201,COG0265@1,COG0265@2 NA|NA|NA O PDZ DHR GLGF domain protein MAG.T2.48_00012 28444.JODQ01000005_gene1396 5.4e-15 87.8 Streptosporangiales Bacteria 2IHGE@201174,4EJG8@85012,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.48_00013 1444711.CCJF01000005_gene821 1.4e-63 250.4 Chlamydiae rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192,2.1.1.224 ko:K06941,ko:K15632 ko00000,ko01000,ko01504,ko03009 Bacteria 2JFUQ@204428,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T2.48_00014 485915.Dret_2330 2.3e-21 108.6 Deltaproteobacteria Bacteria 1MZ60@1224,2WW9K@28221,431TK@68525,COG3952@1,COG3952@2 NA|NA|NA S PFAM lipid A biosynthesis domain protein MAG.T2.48_00015 1210884.HG799462_gene8097 2.3e-21 108.6 Planctomycetes fdx GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 ko:K04755 ko00000 Bacteria 2J33M@203682,COG0633@1,COG0633@2 NA|NA|NA C 2Fe-2S iron-sulfur cluster binding domain MAG.T2.48_00016 1196083.SALWKB12_0188 6e-13 79.7 Neisseriales iscX GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 Bacteria 1N7C1@1224,2KRVE@206351,2VVQU@28216,COG2975@1,COG2975@2 NA|NA|NA S Iron-sulphur cluster assembly MAG.T2.48_00017 886293.Sinac_1701 2.4e-123 448.7 Planctomycetes Bacteria 2IYR5@203682,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase MAG.T2.48_00018 1123508.JH636441_gene3045 1.5e-77 298.5 Planctomycetes Bacteria 2IY7X@203682,COG0457@1,COG0457@2 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.48_00019 344747.PM8797T_03935 3.1e-253 881.7 Planctomycetes Bacteria 2IXP3@203682,COG0457@1,COG0457@2 NA|NA|NA C Cytochrome c554 and c-prime MAG.T2.48_00020 713587.THITH_07385 1.6e-141 510.0 Proteobacteria Bacteria 1QXGV@1224,COG0457@1,COG0457@2 NA|NA|NA S ASPIC and UnbV MAG.T2.48_00021 204669.Acid345_2776 1.5e-41 176.4 Acidobacteriia ko:K03589,ko:K07491 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 2JN69@204432,3Y81S@57723,COG1943@1,COG1943@2 NA|NA|NA L DNA binding domain with preference for A/T rich regions MAG.T2.48_00022 179408.Osc7112_5529 1.4e-10 75.5 Oscillatoriales Bacteria 1G2XZ@1117,1HEEK@1150,COG2931@1,COG2931@2 NA|NA|NA Q Integrin alpha (beta-propellor repeats). MAG.T2.48_00023 497964.CfE428DRAFT_0572 3.5e-60 239.6 Verrucomicrobia Bacteria 46T3U@74201,COG3488@1,COG3488@2 NA|NA|NA C Di-haem oxidoreductase, putative peroxidase MAG.T2.48_00025 1382359.JIAL01000001_gene2748 8e-74 285.0 Acidobacteriia Bacteria 2JHSD@204432,3Y3HT@57723,COG0457@1,COG0457@2 NA|NA|NA S ASPIC and UnbV MAG.T2.48_00026 631362.Thi970DRAFT_02731 2.4e-97 362.8 Chromatiales cls ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1MWUW@1224,1RPQG@1236,1WXED@135613,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol MAG.T2.48_00027 1142394.PSMK_02080 2.1e-31 142.1 Planctomycetes greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2IZWB@203682,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides MAG.T2.48_00029 1142394.PSMK_01180 4.3e-22 112.1 Bacteria ftsQ ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria COG1589@1,COG1589@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly MAG.T2.48_00030 756272.Plabr_1906 2e-27 129.4 Planctomycetes Bacteria 2J3MF@203682,COG4978@1,COG4978@2 NA|NA|NA KT PFAM SOUL heme-binding protein MAG.T2.48_00031 1210884.HG799465_gene11874 4.4e-81 309.3 Planctomycetes Bacteria 2IZ9P@203682,COG5316@1,COG5316@2 NA|NA|NA S N-terminal domain of unknown function (DUF4140) MAG.T2.48_00032 1142394.PSMK_20580 4.8e-70 271.6 Planctomycetes ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2IZHT@203682,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family MAG.T2.48_00033 1123242.JH636436_gene467 7.9e-57 227.6 Planctomycetes murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2IYGQ@203682,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation MAG.T2.48_00034 1142394.PSMK_24040 9.1e-111 407.5 Planctomycetes murC 6.3.2.4,6.3.2.8 ko:K01921,ko:K01924 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2IYEH@203682,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family MAG.T2.48_00035 1142394.PSMK_17470 5e-153 547.7 Planctomycetes ko:K07713 ko02020,map02020 M00499 ko00000,ko00001,ko00002,ko02022 Bacteria 2IWYY@203682,COG2204@1,COG2204@2 NA|NA|NA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains MAG.T2.48_00036 1142394.PSMK_15780 1.9e-29 137.5 Bacteria lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 Bacteria COG0795@1,COG0795@2 NA|NA|NA M lipopolysaccharide-transporting ATPase activity MAG.T2.48_00037 1142394.PSMK_15800 1.2e-40 174.1 Planctomycetes ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 2IZHF@203682,COG0795@1,COG0795@2 NA|NA|NA S Permease YjgP YjgQ family MAG.T2.48_00039 1142394.PSMK_20920 3.8e-34 152.5 Bacteria 3.1.3.16,5.2.1.8 ko:K03769,ko:K07533,ko:K20074 ko00000,ko01000,ko01009,ko03110 Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity MAG.T2.48_00041 1142394.PSMK_12770 4.6e-42 179.9 Planctomycetes Bacteria 2IX04@203682,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family MAG.T2.48_00042 1142394.PSMK_01590 3.2e-36 159.5 Planctomycetes flgI ko:K02394 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IZDW@203682,COG1706@1,COG1706@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation MAG.T2.48_00045 1142394.PSMK_01560 8.1e-57 228.4 Planctomycetes flgK 3.5.1.56 ko:K02388,ko:K02390,ko:K02396,ko:K03418,ko:K07004,ko:K15125,ko:K21012 ko00630,ko02025,ko02040,ko05133,map00630,map02025,map02040,map05133 R02509 RC00111,RC00731 ko00000,ko00001,ko00536,ko01000,ko02035 Bacteria 2IXRV@203682,COG1256@1,COG1256@2,COG1749@1,COG1749@2 NA|NA|NA N flagellar hook-associated protein MAG.T2.48_00046 1142394.PSMK_01550 1e-35 158.3 Planctomycetes flgL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IZMB@203682,COG1344@1,COG1344@2 NA|NA|NA N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella MAG.T2.48_00047 1142394.PSMK_01540 6.3e-25 120.6 Planctomycetes fliW ko:K13626 ko00000,ko02035 Bacteria 2J04H@203682,COG1699@1,COG1699@2 NA|NA|NA S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum MAG.T2.48_00048 314230.DSM3645_08472 3.2e-17 94.4 Planctomycetes csrA ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Bacteria 2J0YE@203682,COG1551@1,COG1551@2 NA|NA|NA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding MAG.T2.48_00049 1142394.PSMK_01520 7.7e-67 261.5 Planctomycetes flaC ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Bacteria 2IX6G@203682,COG1344@1,COG1344@2 NA|NA|NA N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella MAG.T2.48_00051 344747.PM8797T_17464 2.8e-23 114.8 Planctomycetes rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J02D@203682,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit MAG.T2.48_00054 1142394.PSMK_03510 5.8e-43 181.0 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ91@203682,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.48_00055 1267535.KB906767_gene2263 1.3e-155 556.2 Acidobacteriia hpnH Bacteria 2JI93@204432,3Y2JV@57723,COG0535@1,COG0535@2 NA|NA|NA S TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH MAG.T2.48_00056 1123508.JH636441_gene3462 1.9e-48 200.3 Planctomycetes 3.5.1.81 ko:K06015 R02192 RC00064,RC00328 ko00000,ko01000 Bacteria 2IY88@203682,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase class C MAG.T2.48_00057 94624.Bpet2842 7.1e-28 131.0 Alcaligenaceae trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1RA87@1224,2VPZV@28216,3T3HR@506,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family MAG.T2.48_00058 562970.Btus_2368 2.5e-113 415.6 Alicyclobacillaceae citZ 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPS@1239,278TC@186823,4H9YE@91061,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain MAG.T2.48_00059 886293.Sinac_0263 3.8e-43 181.8 Planctomycetes rnaZ 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 2J26U@203682,COG1234@1,COG1234@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T2.48_00060 237368.SCABRO_01544 1e-21 111.7 Bacteria Bacteria COG3170@1,COG3170@2 NA|NA|NA NU translation initiation factor activity MAG.T2.48_00063 1123274.KB899410_gene3495 5.5e-07 63.9 Spirochaetes Bacteria 2J6X7@203691,COG4254@1,COG4254@2 NA|NA|NA S FecR protein MAG.T2.48_00064 596151.DesfrDRAFT_3027 1.2e-46 195.3 Desulfovibrionales 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1V@1224,2M92Z@213115,2WIUS@28221,42N5S@68525,COG2114@1,COG2114@2,COG4252@1,COG4252@2 NA|NA|NA T SMART Adenylyl cyclase class-3 4 guanylyl cyclase MAG.T2.48_00065 1403819.BATR01000067_gene2010 5.4e-118 430.6 Verrucomicrobiae ppk2 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2IVFJ@203494,46UWN@74201,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T2.48_00066 335543.Sfum_3923 3e-115 422.5 Syntrophobacterales lprN Bacteria 1MUA8@1224,2MRI6@213462,2WIQX@28221,42MRU@68525,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T2.48_00067 706587.Desti_0329 4.3e-71 275.4 Deltaproteobacteria lmxE ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MU78@1224,2WK00@28221,42P19@68525,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_00068 706587.Desti_1330 6.5e-289 1000.3 Syntrophobacterales Bacteria 1MU48@1224,2MQUP@213462,2WJVV@28221,42MF6@68525,COG0841@1,COG0841@2 NA|NA|NA U Hydrophobe amphiphile Efflux-1 (HAE1) family MAG.T2.48_00069 234267.Acid_2891 1.8e-271 941.8 Acidobacteria glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 3Y2SX@57723,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family MAG.T2.48_00070 448385.sce6543 4.3e-72 278.9 Deltaproteobacteria rsbU 3.1.3.3,4.6.1.1 ko:K01079,ko:K01768,ko:K07315 ko00230,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko02025,ko04113,ko04213,map00230,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map02025,map04113,map04213 M00020,M00695 R00089,R00434,R00582 RC00017,RC00295 ko00000,ko00001,ko00002,ko01000,ko01009,ko03021 Bacteria 1PFBF@1224,2WN52@28221,42RAR@68525,COG2203@1,COG2203@2,COG2208@1,COG2208@2 NA|NA|NA T Protein phosphatase 2C domain MAG.T2.48_00071 794903.OPIT5_28785 1.8e-142 513.1 Opitutae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 3K7GK@414999,46UY5@74201,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T2.48_00072 794903.OPIT5_28790 6.7e-135 488.0 Opitutae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 3K7GE@414999,46UPX@74201,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T2.48_00073 1142394.PSMK_22990 2.8e-161 575.1 Planctomycetes eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2IXRG@203682,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis MAG.T2.48_00074 1123508.JH636442_gene4011 8.2e-63 247.7 Planctomycetes Bacteria 2IZKG@203682,COG1052@1,COG1052@2 NA|NA|NA CH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MAG.T2.48_00075 1123242.JH636434_gene3713 5e-49 201.4 Planctomycetes motA ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 2IY3Y@203682,COG1291@1,COG1291@2 NA|NA|NA N COG1291 Flagellar motor component MAG.T2.48_00076 243090.RB9271 1.7e-13 83.6 Planctomycetes motB ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 2IZFU@203682,COG1360@1,COG1360@2 NA|NA|NA N COG1360 Flagellar motor protein MAG.T2.48_00077 794903.OPIT5_10485 3.8e-43 183.0 Opitutae 3.4.21.62 ko:K01342,ko:K12287,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko02044,ko03110 Bacteria 3K9SW@414999,46WMI@74201,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.48_00078 1142394.PSMK_18310 8.6e-163 580.5 Planctomycetes phnV ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 2J51F@203682,COG1178@1,COG1178@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component MAG.T2.48_00079 1047013.AQSP01000139_gene2416 1.2e-69 270.8 unclassified Bacteria aprN Bacteria 2NNSK@2323,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T2.48_00081 1122169.AREN01000023_gene1638 1.1e-97 364.0 Legionellales ko:K03294 ko00000 2.A.3.2 Bacteria 1JDWA@118969,1MXNJ@1224,1RMKV@1236,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T2.48_00082 1142394.PSMK_16630 6.5e-171 607.1 Planctomycetes nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IY7J@203682,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_00083 1142394.PSMK_16650 4.7e-39 167.9 Planctomycetes nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 ko:K00334,ko:K00335,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 2IZEQ@203682,COG1905@1,COG1905@2 NA|NA|NA C Thioredoxin-like [2Fe-2S] ferredoxin MAG.T2.48_00085 1142394.PSMK_16690 6.7e-134 484.2 Planctomycetes nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IXJ8@203682,COG1894@1,COG1894@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region MAG.T2.48_00086 1142394.PSMK_14490 1e-17 96.7 Planctomycetes ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2J0MV@203682,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA MAG.T2.48_00087 1142394.PSMK_14480 1.3e-54 220.7 Planctomycetes tlyC ko:K06189 ko00000,ko02000 9.A.40.1.2 Bacteria 2IZAU@203682,COG1253@1,COG1253@2 NA|NA|NA S COG1253 Hemolysins and related MAG.T2.48_00088 378806.STAUR_4765 1.9e-11 76.6 Proteobacteria ko:K07052 ko00000 Bacteria 1R4UU@1224,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T2.48_00089 1142394.PSMK_01830 1.1e-82 313.2 Planctomycetes lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 2IYUP@203682,COG1137@1,COG1137@2 NA|NA|NA S ABC-type (unclassified) transport system ATPase MAG.T2.48_00090 1142394.PSMK_07450 3.2e-15 88.6 Planctomycetes Bacteria 2DVHI@1,2J0QY@203682,32UZG@2 NA|NA|NA S PFAM PEGA domain MAG.T2.48_00091 91464.S7335_4149 2.1e-30 139.4 Cyanobacteria pagN ko:K12980 ko00000,ko01005 Bacteria 1GDS8@1117,COG3637@1,COG3637@2 NA|NA|NA M Lipid A 3-O-deacylase (PagL) MAG.T2.48_00092 344747.PM8797T_29832 2.1e-87 329.3 Planctomycetes galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY22@203682,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family MAG.T2.48_00093 234267.Acid_3549 2.9e-23 114.8 Acidobacteria Bacteria 29E6W@1,3014W@2,3Y4JR@57723 NA|NA|NA MAG.T2.48_00095 1142394.PSMK_30130 2.3e-26 125.6 Planctomycetes Bacteria 2IZRH@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.48_00096 1142394.PSMK_14770 1.5e-82 313.2 Planctomycetes waaM 2.3.1.241,2.3.1.265 ko:K02517,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IY7N@203682,COG1560@1,COG1560@2 NA|NA|NA M Lipid A biosynthesis acyltransferase MAG.T2.48_00097 1142394.PSMK_14780 1.8e-25 124.0 Bacteria tcdA2 ko:K03497,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03000,ko03036,ko04812 Bacteria COG0497@1,COG0497@2 NA|NA|NA L DNA recombination MAG.T2.48_00098 756272.Plabr_3182 7.9e-153 547.4 Planctomycetes xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IYEE@203682,COG2804@1,COG2804@2 NA|NA|NA NU COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB MAG.T2.48_00099 1142394.PSMK_22390 1.4e-09 68.9 Bacteria rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0268@1,COG0268@2 NA|NA|NA J rRNA binding MAG.T2.48_00100 344747.PM8797T_12428 8.9e-20 104.4 Planctomycetes ko:K07052 ko00000 Bacteria 2J06D@203682,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T2.48_00101 497964.CfE428DRAFT_2026 3.7e-52 212.2 Bacteria mgtE1 ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter MAG.T2.48_00102 1210884.HG799465_gene11378 3.9e-37 161.4 Planctomycetes kdsC 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IZM6@203682,COG1778@1,COG1778@2 NA|NA|NA S TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family MAG.T2.48_00104 118163.Ple7327_3056 2.1e-07 63.2 Cyanobacteria Bacteria 1G65V@1117,2A69T@1,30V2E@2 NA|NA|NA MAG.T2.48_00105 1117647.M5M_17215 1.1e-56 226.5 unclassified Gammaproteobacteria kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 Bacteria 1JAQ6@118884,1MW68@1224,1RXYM@1236,COG3483@1,COG3483@2 NA|NA|NA E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety MAG.T2.48_00106 1123060.JONP01000003_gene261 3.3e-119 435.6 Rhodospirillales carC 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 1MV2R@1224,2JQE4@204441,2TSR0@28211,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase MAG.T2.48_00107 1123508.JH636445_gene6501 9.4e-51 208.0 Planctomycetes 1.2.1.3,1.2.99.10 ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZ2G@203682,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.48_00108 426117.M446_3156 9.6e-135 487.3 Methylobacteriaceae crtP 1.14.99.44 ko:K10210 ko00906,map00906 R07654,R09671,R09727,R09728 RC00254,RC02089,RC02626,RC02638 ko00000,ko00001,ko01000 Bacteria 1JRHK@119045,1MV2R@1224,2TVAD@28211,COG1233@1,COG1233@2 NA|NA|NA Q TIGRFAM phytoene desaturase MAG.T2.48_00109 1123501.KB902285_gene2134 9.2e-33 147.5 Alphaproteobacteria 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1R787@1224,2U4Y1@28211,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T2.48_00110 1123501.KB902285_gene2133 2.5e-79 302.8 Alphaproteobacteria ko:K14597 ko00906,map00906 R07544,R07546 RC00262 ko00000,ko00001 Bacteria 1MW1E@1224,2U30S@28211,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.48_00112 1144275.COCOR_06603 1.7e-242 845.9 Deltaproteobacteria lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1MUSW@1224,2WMDY@28221,42Q75@68525,COG1201@1,COG1201@2 NA|NA|NA L Dead deah box MAG.T2.48_00113 1502852.FG94_02429 9.5e-10 68.9 Betaproteobacteria ko:K07483,ko:K07497 ko00000 Bacteria 1N1MP@1224,2VU5E@28216,COG2963@1,COG2963@2 NA|NA|NA L Transposase MAG.T2.48_00114 330214.NIDE0139 4.7e-183 647.9 Nitrospirae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 3J15I@40117,COG0286@1,COG0286@2 NA|NA|NA V Product type e enzyme MAG.T2.48_00115 273068.TTE1545 1.2e-44 187.6 Thermoanaerobacterales hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1V78B@1239,25N35@186801,42HJS@68295,COG0732@1,COG0732@2 NA|NA|NA L PFAM restriction modification system DNA specificity domain MAG.T2.48_00116 1122222.AXWR01000018_gene2633 8.6e-281 973.0 Deinococcus-Thermus 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1WN70@1297,COG4096@1,COG4096@2 NA|NA|NA L Type I site-specific restriction-modification system, R (Restriction) subunit and related MAG.T2.48_00119 1123242.JH636435_gene2431 1.3e-13 82.8 Bacteria Bacteria COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.48_00120 378806.STAUR_6769 4.6e-51 208.0 Myxococcales MA20_22045 ko:K06953 ko00000 Bacteria 1RC5G@1224,2X36F@28221,2YZDK@29,43F2X@68525,COG1407@1,COG1407@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T2.48_00121 756272.Plabr_3305 1.6e-200 706.1 Planctomycetes ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2IYCU@203682,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system ATPase and permease MAG.T2.48_00122 420324.KI911934_gene170 4.4e-208 731.1 Methylobacteriaceae yfbS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1JS1S@119045,1MU0K@1224,2TSFS@28211,COG0471@1,COG0471@2,COG0490@1,COG0490@2 NA|NA|NA P TrkA-C domain MAG.T2.48_00123 366394.Smed_5237 2.4e-180 638.6 Rhizobiaceae ydaH ko:K12942 ko00000 Bacteria 1MUJ1@1224,2U1AP@28211,4BCF3@82115,COG2978@1,COG2978@2 NA|NA|NA H AbgT putative transporter family MAG.T2.48_00124 1502851.FG93_03080 6.4e-128 464.2 Bradyrhizobiaceae MA20_17715 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1MV7D@1224,2U0U8@28211,3JWJR@41294,COG2195@1,COG2195@2 NA|NA|NA E M42 glutamyl aminopeptidase MAG.T2.48_00125 1120949.KB903311_gene694 3.9e-70 272.3 Micromonosporales Bacteria 2IA2X@201174,4DD97@85008,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter MAG.T2.48_00126 1142394.PSMK_22270 8.5e-21 108.2 Bacteria Bacteria COG3568@1,COG3568@2 NA|NA|NA N Endonuclease Exonuclease Phosphatase MAG.T2.48_00127 530564.Psta_3810 1.5e-156 559.3 Planctomycetes trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXA5@203682,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine MAG.T2.48_00129 1142394.PSMK_02530 3.1e-51 209.1 Planctomycetes pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.5,2.7.8.8 ko:K00995,ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800,R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZHR@203682,COG1183@1,COG1183@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T2.48_00131 1444711.CCJF01000005_gene155 1.1e-94 353.6 Chlamydiae fas6 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2JGZ7@204428,COG1611@1,COG1611@2 NA|NA|NA S Possible lysine decarboxylase MAG.T2.48_00132 314230.DSM3645_22786 6.2e-11 77.4 Planctomycetes Bacteria 2IYVI@203682,COG2982@1,COG2982@2 NA|NA|NA M Protein involved in outer membrane biogenesis MAG.T2.48_00134 1121013.P873_12305 1.7e-31 143.3 Xanthomonadales Bacteria 1MUUV@1224,1RMJU@1236,1X51Z@135614,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MAG.T2.48_00138 1142394.PSMK_08040 4.6e-290 1004.2 Planctomycetes valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Bacteria 2IWU4@203682,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner MAG.T2.48_00139 1142394.PSMK_06260 5.7e-09 68.9 Bacteria Bacteria COG0308@1,COG0308@2 NA|NA|NA E peptide catabolic process MAG.T2.48_00142 1192034.CAP_4939 5.7e-14 85.1 Myxococcales ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1MWVF@1224,2WKNZ@28221,2YVK6@29,42PQA@68525,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein MAG.T2.48_00143 1142394.PSMK_21000 2.6e-37 162.9 Planctomycetes ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2J03D@203682,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily MAG.T2.48_00144 301.JNHE01000009_gene3249 2.6e-26 125.9 Pseudomonas aeruginosa group hmuV GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030001,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 1.14.15.20,3.6.3.33,3.6.3.34 ko:K02013,ko:K06074,ko:K21480 ko00860,ko01100,ko01110,ko02010,map00860,map01100,map01110,map02010 M00240,M00241 R11579 RC01270 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.13,3.A.1.14 Bacteria 1RD7N@1224,1RPUV@1236,1YDFD@136841,COG4559@1,COG4559@2 NA|NA|NA P Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system MAG.T2.48_00146 521674.Plim_0064 2.7e-26 125.2 Planctomycetes accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 2IZJ6@203682,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA MAG.T2.48_00147 1142394.PSMK_21030 7.5e-162 577.0 Planctomycetes accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWZV@203682,COG0439@1,COG0439@2 NA|NA|NA I Biotin carboxylase MAG.T2.48_00149 1142394.PSMK_14640 3.9e-67 262.7 Planctomycetes ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IZ37@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase MAG.T2.48_00150 1142394.PSMK_14630 1.4e-103 383.3 Planctomycetes ko:K02669,ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX6Y@203682,COG2805@1,COG2805@2 NA|NA|NA NU twitching motility protein MAG.T2.48_00151 1142394.PSMK_12620 2e-163 582.4 Planctomycetes guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IX43@203682,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth MAG.T2.48_00152 1116369.KB890024_gene106 3.8e-14 87.0 Phyllobacteriaceae Bacteria 1N482@1224,2D4E5@1,2UE4H@28211,32TGX@2,43I07@69277 NA|NA|NA MAG.T2.48_00153 1380350.JIAP01000001_gene1653 1.6e-10 75.1 Phyllobacteriaceae Bacteria 1N482@1224,2D4E5@1,2UE4H@28211,32TGX@2,43I07@69277 NA|NA|NA MAG.T2.48_00155 1267535.KB906767_gene5181 2.3e-87 329.3 Acidobacteriia ctaC GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 ko:K02275,ko:K17223 ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120 M00155,M00595 R00081,R10151 RC00016,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 2JJ01@204432,3Y2GJ@57723,COG1622@1,COG1622@2,COG2010@1,COG2010@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T2.48_00156 1267535.KB906767_gene5180 9.2e-215 753.1 Acidobacteriia coxA 1.9.3.1 ko:K02274,ko:K15408 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2JIKT@204432,3Y37Z@57723,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B MAG.T2.48_00157 401053.AciPR4_1736 6.2e-46 190.7 Acidobacteriia 1.9.3.1 ko:K02276,ko:K02299 ko00190,ko01100,map00190,map01100 M00155,M00417 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.5,3.D.4.6 Bacteria 2JJ26@204432,3Y4DA@57723,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase subunit III MAG.T2.48_00158 1267533.KB906738_gene2420 1.7e-52 213.0 Acidobacteriia Bacteria 2C2MA@1,2JIC2@204432,2Z87X@2,3Y4B4@57723 NA|NA|NA MAG.T2.48_00159 1382359.JIAL01000001_gene1129 3.6e-31 142.1 Acidobacteriia soxA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 ko:K00406,ko:K03889,ko:K17222,ko:K19713 ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020 M00151,M00156,M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.3 Bacteria 2JJD9@204432,3Y4N3@57723,COG3258@1,COG3258@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III MAG.T2.48_00160 1382359.JIAL01000001_gene1128 4.6e-48 198.0 Acidobacteriia 1.3.5.1,1.3.5.4 ko:K00240,ko:K03886 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00151,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2JKI7@204432,3Y4I1@57723,COG0723@1,COG0723@2 NA|NA|NA C PFAM Rieske 2Fe-2S iron-sulphur domain MAG.T2.48_00161 1382359.JIAL01000001_gene1127 3.2e-153 548.5 Acidobacteriia ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 ko00000,ko00001,ko00002,ko03029 Bacteria 2JHJQ@204432,3Y2JP@57723,COG1290@1,COG1290@2,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome b(N-terminal)/b6/petB MAG.T2.48_00162 1267535.KB906767_gene5174 3.7e-170 605.5 Acidobacteria vnfA ko:K02351,ko:K07245 ko00000,ko02000 9.B.62.1 Bacteria 3Y3CM@57723,COG0348@1,COG0348@2,COG3336@1,COG3336@2 NA|NA|NA C PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related MAG.T2.48_00164 448385.sce7671 3e-85 322.4 Myxococcales 1.1.3.46 ko:K16422 ko00261,ko01055,ko01130,map00261,map01055,map01130 R06633 RC00240 ko00000,ko00001,ko01000 Bacteria 1MUEZ@1224,2WQVP@28221,2YU42@29,42T5F@68525,COG1304@1,COG1304@2 NA|NA|NA C FMN-dependent dehydrogenase MAG.T2.48_00165 1123368.AUIS01000006_gene572 2.6e-52 212.2 Acidithiobacillales yoqW Bacteria 1RER4@1224,1RSBH@1236,2NCEE@225057,COG2135@1,COG2135@2 NA|NA|NA S SOS response associated peptidase (SRAP) MAG.T2.48_00167 1089552.KI911559_gene3572 4.6e-09 68.6 Rhodospirillales imuA GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K14160 ko00000,ko03400 Bacteria 1MY56@1224,2JTBE@204441,2TT91@28211,COG4544@1,COG4544@2 NA|NA|NA S SOS response MAG.T2.48_00169 1463864.JOGO01000012_gene5585 7.2e-28 131.3 Actinobacteria 2.7.13.3 ko:K07675 ko02020,map02020 M00473 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2HDZV@201174,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T2.48_00170 324602.Caur_0022 3e-47 195.3 Chloroflexia ko:K02282 ko00000,ko02035,ko02044 Bacteria 2G6PA@200795,377BM@32061,COG2197@1,COG2197@2 NA|NA|NA K Sigma-70, region 4 type 2 MAG.T2.48_00171 794903.OPIT5_17215 2.8e-11 76.3 Bacteria Bacteria 2EGE2@1,33A5Z@2 NA|NA|NA MAG.T2.48_00174 96561.Dole_1787 2e-18 100.9 Desulfobacterales 3.2.1.81 ko:K01219,ko:K03749,ko:K15725 ko00000,ko01000,ko02000 1.B.17.2.2 Bacteria 1N4S6@1224,2MNRP@213118,2X729@28221,43BRE@68525,COG1653@1,COG1653@2,COG3210@1,COG3210@2,COG3266@1,COG3266@2,COG5492@1,COG5492@2 NA|NA|NA G domain protein MAG.T2.48_00175 1161401.ASJA01000005_gene2354 2e-40 174.1 Hyphomonadaceae imuB 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1MU5X@1224,2TQVR@28211,43XAB@69657,COG0389@1,COG0389@2 NA|NA|NA L COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair MAG.T2.48_00176 1380394.JADL01000008_gene3629 2.6e-286 991.9 Rhodospirillales dnaE2 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MUE4@1224,2JR16@204441,2TRUB@28211,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase MAG.T2.48_00177 314230.DSM3645_30056 4.6e-19 101.3 Planctomycetes Bacteria 2J0DS@203682,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T2.48_00178 1142394.PSMK_01000 2.7e-71 275.4 Planctomycetes uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2IX6Z@203682,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T2.48_00179 1142394.PSMK_01010 3.2e-123 448.7 Planctomycetes purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Bacteria 2IWZH@203682,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP MAG.T2.48_00180 1142394.PSMK_13450 6.5e-83 314.7 Planctomycetes hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2IWR5@203682,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound MAG.T2.48_00181 1396418.BATQ01000072_gene581 5.4e-224 785.0 Verrucomicrobiae hyuA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016885,GO:0017144,GO:0018710,GO:0042180,GO:0043443,GO:0044237,GO:0044281,GO:0071704,GO:1901568,GO:1902224 3.5.2.14,3.5.2.9,6.4.1.6,6.4.1.8 ko:K01469,ko:K01473,ko:K01474,ko:K10701,ko:K10855 ko00330,ko00480,ko00642,ko01100,ko01120,ko01220,map00330,map00480,map00642,map01100,map01120,map01220 R00251,R03187,R05453 RC00040,RC00553,RC00632 ko00000,ko00001,ko01000 iNJ661.Rv0266c Bacteria 2IU32@203494,46UMR@74201,COG0145@1,COG0145@2,COG0146@1,COG0146@2 NA|NA|NA EQ Hydantoinase B/oxoprolinase MAG.T2.48_00183 1128421.JAGA01000001_gene2398 2.5e-47 196.1 Bacteria hisZ 6.1.1.21 ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria COG0124@1,COG0124@2 NA|NA|NA J histidine-tRNA ligase activity MAG.T2.48_00184 1128421.JAGA01000001_gene2399 8e-127 460.7 Bacteria fahA 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4620 Bacteria COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase MAG.T2.48_00185 448385.sce2670 2.1e-24 119.4 Proteobacteria Bacteria 1QWJG@1224,2DQ41@1,334MP@2 NA|NA|NA S Kazal type serine protease inhibitors MAG.T2.48_00186 1142394.PSMK_18350 3.3e-12 78.6 Planctomycetes ko:K09005 ko00000 Bacteria 2J462@203682,COG1430@1,COG1430@2 NA|NA|NA S Uncharacterized ACR, COG1430 MAG.T2.48_00187 1444309.JAQG01000191_gene642 2.3e-126 459.1 Paenibacillaceae hmgA 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYZ0@1239,26V1U@186822,4HCCC@91061,COG3508@1,COG3508@2 NA|NA|NA Q homogentisate 1,2-dioxygenase MAG.T2.48_00188 160492.XF_0939 1.5e-18 100.1 Xanthomonadales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1MUBN@1224,1RN7F@1236,1X3AV@135614,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T2.48_00190 1313301.AUGC01000006_gene67 5e-112 411.4 Bacteroidetes hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 4NFI7@976,COG3185@1,COG3185@2 NA|NA|NA E 4-hydroxyphenylpyruvate dioxygenase MAG.T2.48_00192 1242864.D187_008882 1.4e-47 196.1 Deltaproteobacteria apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1MVZ6@1224,2WP5X@28221,42QSH@68525,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis MAG.T2.48_00193 1142394.PSMK_16420 5.8e-36 156.8 Planctomycetes groES ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IZTF@203682,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T2.48_00194 292415.Tbd_0954 5.5e-54 218.8 Hydrogenophilales aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390 Bacteria 1KS2U@119069,1MWMK@1224,2VGZF@28216,COG0128@1,COG0128@2 NA|NA|NA E EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) MAG.T2.48_00195 1142394.PSMK_06310 1.5e-104 387.1 Planctomycetes msbA ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2IXKY@203682,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system ATPase and permease MAG.T2.48_00196 1454004.AW11_03811 1e-09 70.9 Bacteria yjfP GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0034338,GO:0052689 ko:K06889 ko00000 Bacteria COG1073@1,COG1073@2 NA|NA|NA S thiolester hydrolase activity MAG.T2.48_00197 290397.Adeh_1733 3.6e-22 112.5 Myxococcales rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1MXKW@1224,2WWMK@28221,2Z2ZS@29,42U1F@68525,COG0742@1,COG0742@2 NA|NA|NA L Methyltransferase domain MAG.T2.48_00198 243090.RB87 8.5e-13 81.6 Planctomycetes GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 4.2.1.129,5.4.99.17,5.5.1.16 ko:K06045,ko:K17811 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2J1Q5@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.48_00199 1089546.AQUI01000002_gene621 1.7e-239 835.9 Actinopolysporales otsB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K01087,ko:K16055 ko00500,ko01100,map00500,map01100 R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT20 iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495 Bacteria 2GJAD@201174,408F7@622450,COG1877@1,COG1877@2,COG3387@1,COG3387@2 NA|NA|NA G Glycosyl hydrolases family 15 MAG.T2.48_00200 404589.Anae109_2390 1.1e-261 909.4 Myxococcales otsA 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 ko:K00697,ko:K13057,ko:K20436 ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130 M00815 R02737,R08946,R10525,R11239,R11250,R11306,R11497 RC00005,RC00049,RC02748,RC03400,RC03401 ko00000,ko00001,ko00002,ko01000,ko01003 GT20,GT4 Bacteria 1MUIY@1224,2WJX9@28221,2YU3V@29,42NBU@68525,COG0380@1,COG0380@2 NA|NA|NA G glycosyl transferase family MAG.T2.48_00201 344747.PM8797T_12493 5.4e-38 164.9 Planctomycetes ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21030,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS20335 Bacteria 2IYXJ@203682,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) MAG.T2.48_00203 1142394.PSMK_30990 9.3e-151 540.8 Planctomycetes feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 2IYCI@203682,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system MAG.T2.48_00206 530564.Psta_2032 6.9e-14 85.9 Planctomycetes bztC ko:K09971 ko02010,map02010 M00232 ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 Bacteria 2IYM0@203682,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T2.48_00207 1407650.BAUB01000015_gene2279 2.3e-30 139.8 Cyanobacteria ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 1G33G@1117,COG1840@1,COG1840@2 NA|NA|NA P 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein MAG.T2.48_00208 243090.RB10820 2.5e-20 107.8 Planctomycetes Bacteria 2IYRP@203682,COG3391@1,COG3391@2 NA|NA|NA P RING finger protein MAG.T2.48_00209 886293.Sinac_2617 4.9e-129 469.2 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IXKI@203682,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.48_00210 886293.Sinac_2616 6e-98 364.4 Planctomycetes ko:K03924 ko00000,ko01000 Bacteria 2IY1M@203682,COG0714@1,COG0714@2 NA|NA|NA S ATPase associated with MAG.T2.48_00211 575540.Isop_2743 2.1e-73 282.7 Planctomycetes Bacteria 2IY59@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.48_00212 530564.Psta_2131 4.8e-64 252.7 Planctomycetes Bacteria 2IXP0@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A MAG.T2.48_00214 1142394.PSMK_05250 7.9e-37 160.6 Planctomycetes yggX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 Bacteria 2J0X4@203682,COG0457@1,COG0457@2,COG2924@1,COG2924@2 NA|NA|NA CO Bacterial Fe(2+) trafficking MAG.T2.48_00215 913865.DOT_0776 7.6e-68 264.2 Peptococcaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,248CQ@186801,260Y3@186807,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily MAG.T2.48_00216 1142394.PSMK_20080 4e-24 117.9 Planctomycetes Bacteria 2J1JU@203682,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase MAG.T2.48_00217 1142394.PSMK_06010 3.4e-11 75.9 Bacteria CP_0228 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria COG1579@1,COG1579@2 NA|NA|NA MAG.T2.48_00218 1142394.PSMK_16380 3.3e-30 139.0 Planctomycetes cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2J032@203682,COG4589@1,COG4589@2 NA|NA|NA S Phosphatidate cytidylyltransferase MAG.T2.48_00219 1123242.JH636438_gene5868 4.9e-18 97.1 Planctomycetes Bacteria 2J06B@203682,COG0607@1,COG0607@2 NA|NA|NA P COG0607 Rhodanese-related sulfurtransferase MAG.T2.48_00223 1121104.AQXH01000001_gene1930 4.2e-53 214.9 Sphingobacteriia nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1IPXY@117747,4NFF3@976,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T2.48_00226 1142394.PSMK_16190 1.9e-28 132.1 Planctomycetes acpS 2.7.8.7 ko:K00997,ko:K06925 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2IZSD@203682,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein MAG.T2.48_00229 1142394.PSMK_16220 2.5e-102 379.0 Planctomycetes patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IX5E@203682,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T2.48_00230 886293.Sinac_5252 3.5e-100 371.7 Planctomycetes thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149,ko:K03154 ko00730,ko01100,ko04122,map00730,map01100,map04122 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 Bacteria 2IY2Y@203682,COG2022@1,COG2022@2,COG2104@1,COG2104@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S MAG.T2.48_00233 1283299.AUKG01000002_gene4119 7.3e-18 97.1 Rubrobacteria ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IHVJ@201174,4CQKQ@84995,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T2.48_00234 1142394.PSMK_30780 2.8e-108 400.6 Planctomycetes smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2IY32@203682,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T2.48_00235 1142394.PSMK_18820 9.3e-38 165.2 Planctomycetes flgI ko:K02394 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IY0C@203682,COG1413@1,COG1413@2,COG1706@1,COG1706@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation MAG.T2.48_00236 317936.Nos7107_3152 8.2e-36 157.5 Nostocales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1G0FD@1117,1HJDP@1161,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T2.48_00237 864702.OsccyDRAFT_2827 2.1e-42 179.5 Oscillatoriales Bacteria 1G5YB@1117,1HB60@1150,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.48_00238 1173027.Mic7113_4429 2.6e-56 225.7 Oscillatoriales Bacteria 1G495@1117,1H8AF@1150,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase MAG.T2.48_00239 765910.MARPU_10415 7.8e-107 395.6 Chromatiales kefA GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K05802,ko:K06994,ko:K15771,ko:K22051 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3,3.A.1.1.16,3.A.1.1.2 Bacteria 1MWSA@1224,1RMYY@1236,1WXKG@135613,COG1196@1,COG1196@2,COG3264@1,COG3264@2 NA|NA|NA DM mechanosensitive ion channel MAG.T2.48_00240 218851.Aquca_014_00176.1 6.5e-125 454.1 Streptophyta GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 Viridiplantae 37HWK@33090,3G9MN@35493,COG0436@1,KOG0257@2759 NA|NA|NA E Kynurenine--oxoglutarate transaminase MAG.T2.48_00241 1142394.PSMK_05650 7.3e-23 113.2 Planctomycetes rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0XA@203682,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 MAG.T2.48_00242 886293.Sinac_1911 7e-08 64.3 Planctomycetes Bacteria 2B8BF@1,2IZTE@203682,321K5@2 NA|NA|NA S Protein of unknown function DUF2617 MAG.T2.48_00243 338963.Pcar_2009 2.3e-44 186.0 Desulfuromonadales dpo 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWX1@1224,2WMXB@28221,42QXV@68525,43TTD@69541,COG1573@1,COG1573@2 NA|NA|NA L Uracil DNA glycosylase superfamily MAG.T2.48_00244 562970.Btus_0996 1e-31 143.3 Alicyclobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,278GH@186823,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality MAG.T2.48_00245 886293.Sinac_1412 1.2e-37 164.5 Planctomycetes GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 ko:K06990 ko00000,ko04812 Bacteria 2IZEZ@203682,COG1355@1,COG1355@2 NA|NA|NA S Memo-like protein MAG.T2.48_00246 1313301.AUGC01000003_gene2087 8.1e-10 72.4 Bacteroidetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 4NP5H@976,COG2885@1,COG2885@2 NA|NA|NA M InterPro IPR011467 MAG.T2.48_00247 886293.Sinac_2122 5.7e-129 468.0 Planctomycetes ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 2IXSU@203682,COG2317@1,COG2317@2 NA|NA|NA E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues MAG.T2.48_00248 575540.Isop_1610 5.5e-187 661.0 Planctomycetes typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2IY3Q@203682,COG1217@1,COG1217@2 NA|NA|NA T membrane GTPase involved in stress response MAG.T2.48_00249 1242864.D187_003317 1.4e-57 229.9 Deltaproteobacteria cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFX@1224,2WJC3@28221,42MND@68525,COG1045@1,COG1045@2 NA|NA|NA E serine O-acetyltransferase MAG.T2.48_00250 1185876.BN8_04096 8.3e-120 436.8 Cytophagia cysK 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 47JVM@768503,4NDZ9@976,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family MAG.T2.48_00252 247490.KSU1_C1278 1.1e-98 367.1 Planctomycetes lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY8N@203682,COG0527@1,COG0527@2 NA|NA|NA E aspartate kinase, monofunctional class MAG.T2.48_00253 378806.STAUR_4185 8.9e-19 100.5 Myxococcales fur GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K03711 ko00000,ko03000 Bacteria 1RDWJ@1224,2WQKR@28221,2YVE5@29,42MN8@68525,COG0735@1,COG0735@2 NA|NA|NA K Belongs to the Fur family MAG.T2.48_00254 1297617.JPJD01000064_gene3030 1.3e-21 110.2 unclassified Clostridiales yjeE 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1V6CV@1239,24MSS@186801,269HY@186813,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE MAG.T2.48_00255 1142394.PSMK_26870 1.1e-45 190.7 Planctomycetes thiL GO:0008150,GO:0040007 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2977c,iYO844.BSU05900 Bacteria 2IZG9@203682,COG0611@1,COG0611@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 MAG.T2.48_00256 1142394.PSMK_14960 1.7e-89 336.7 Planctomycetes kdtA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 iECNA114_1301.ECNA114_3778,iIT341.HP0957,iUMNK88_1353.UMNK88_4417 Bacteria 2IYCJ@203682,COG1519@1,COG1519@2 NA|NA|NA M transferase MAG.T2.48_00257 1286632.P278_21240 1.1e-11 77.0 Flavobacteriia Bacteria 1I87U@117743,4NH2A@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.48_00264 1142394.PSMK_20230 1.1e-136 493.4 Planctomycetes pilC ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX2A@203682,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretory pathway component PulF MAG.T2.48_00265 1142394.PSMK_20220 3.1e-200 704.9 Planctomycetes gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXGK@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.48_00266 1142394.PSMK_15850 1.7e-143 515.8 Planctomycetes pilT ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IXRP@203682,COG2805@1,COG2805@2 NA|NA|NA NU COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT MAG.T2.48_00267 1142394.PSMK_15860 3e-179 635.2 Planctomycetes gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXSA@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.48_00268 1142394.PSMK_04960 3e-34 152.1 Planctomycetes coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 Bacteria 2IZJA@203682,COG0452@1,COG0452@2 NA|NA|NA H COG0452 Phosphopantothenoylcysteine synthetase decarboxylase MAG.T2.48_00269 595460.RRSWK_03471 2e-47 196.8 Planctomycetes GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 4.2.1.129,5.4.99.17,5.5.1.16 ko:K06045,ko:K17811 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2J1Q5@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.48_00271 1440774.Y900_023755 2.7e-132 478.4 Mycobacteriaceae gnd2 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2620,iNJ661.Rv1122 Bacteria 232XI@1762,2I2DH@201174,COG1023@1,COG1023@2 NA|NA|NA G 6-phosphogluconate dehydrogenase MAG.T2.48_00272 1267535.KB906767_gene3855 2.9e-148 531.9 Acidobacteriia zwf 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JKTN@204432,3Y627@57723,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone MAG.T2.48_00274 886293.Sinac_4835 3.4e-20 106.7 Planctomycetes wspA ko:K03406,ko:K13487 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 2IYQX@203682,COG0840@1,COG0840@2,COG4191@1,COG4191@2 NA|NA|NA NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). MAG.T2.48_00275 999541.bgla_2g22190 1.7e-08 66.2 Burkholderiaceae wspB ko:K03408,ko:K13488 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 1K7UX@119060,1N0R3@1224,2VUQH@28216,COG0835@1,COG0835@2 NA|NA|NA NT PFAM CheW domain protein MAG.T2.48_00276 1390370.O203_14650 4.1e-25 122.5 Pseudomonas aeruginosa group wspC 2.1.1.80 ko:K00575,ko:K13486 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 Bacteria 1MVP3@1224,1S1XK@1236,1YD6W@136841,COG0457@1,COG0457@2,COG1352@1,COG1352@2 NA|NA|NA NT Methyltransferase, chemotaxis proteins MAG.T2.48_00277 1112217.PPL19_02810 6.8e-11 74.3 Bacteria wspD ko:K03408,ko:K03415,ko:K13486,ko:K13489 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria COG0835@1,COG0835@2 NA|NA|NA NT chemotaxis MAG.T2.48_00278 1173028.ANKO01000044_gene768 9.1e-171 607.4 Oscillatoriales wspE GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3,2.7.7.65 ko:K03407,ko:K11444,ko:K13490 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00509 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1G26V@1117,1H78U@1150,COG0643@1,COG0643@2,COG0745@1,COG0745@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T2.48_00279 82654.Pse7367_3365 1.2e-69 270.4 Oscillatoriales cheB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 ko:K03412,ko:K03413,ko:K13491 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00509 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 1G1EA@1117,1H8DX@1150,COG2201@1,COG2201@2 NA|NA|NA NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR MAG.T2.48_00280 526222.Desal_3697 6.6e-109 401.0 Desulfovibrionales 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 1N4K5@1224,2M9XH@213115,2WN9M@28221,42RTP@68525,COG2199@1,COG2208@1,COG2208@2,COG3706@2 NA|NA|NA T Sigma factor PP2C-like phosphatases MAG.T2.48_00281 234267.Acid_6143 1.8e-40 173.3 Bacteria apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria COG1477@1,COG1477@2 NA|NA|NA H protein flavinylation MAG.T2.48_00282 575540.Isop_2477 2.9e-97 362.5 Planctomycetes Bacteria 2IXFW@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.48_00283 761193.Runsl_4066 1.6e-100 373.2 Cytophagia Bacteria 47KYK@768503,4NF9M@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T2.48_00284 1123248.KB893329_gene4430 2.8e-39 169.1 Sphingobacteriia Bacteria 1IPZV@117747,4NEUZ@976,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 MAG.T2.48_00285 745718.JADT01000023_gene1431 3.9e-62 246.5 Flavobacteriia Bacteria 1HZ43@117743,4NDUD@976,COG5276@1,COG5276@2 NA|NA|NA O Zinc metalloprotease (Elastase) MAG.T2.48_00286 159450.NH14_27745 2.9e-73 282.7 Burkholderiaceae 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1K385@119060,1MV70@1224,2VI1Z@28216,COG1858@1,COG1858@2 NA|NA|NA C Di-haem cytochrome c peroxidase MAG.T2.48_00287 400682.PAC_15709245 3.7e-10 73.9 Eukaryota Eukaryota KOG2177@1,KOG2177@2759 NA|NA|NA O zinc ion binding MAG.T2.48_00288 1382359.JIAL01000001_gene558 7.6e-98 364.0 Acidobacteriia icd 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2JIUD@204432,3Y2VW@57723,COG0473@1,COG0473@2 NA|NA|NA CE Isocitrate/isopropylmalate dehydrogenase MAG.T2.48_00289 344747.PM8797T_09279 6.4e-70 271.6 Bacteria 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria COG0578@1,COG0578@2 NA|NA|NA C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family MAG.T2.48_00290 756272.Plabr_2040 2e-53 216.1 Planctomycetes Bacteria 2J1QQ@203682,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T2.48_00291 1142394.PSMK_14520 1.2e-10 74.3 Bacteria Bacteria COG1652@1,COG1652@2 NA|NA|NA S positive regulation of growth rate MAG.T2.48_00292 1142394.PSMK_23630 8.4e-155 555.1 Planctomycetes secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2IYCQ@203682,COG0341@1,COG0341@2,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T2.48_00294 1142394.PSMK_23650 6.8e-109 401.0 Planctomycetes tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 Bacteria 2IWXI@203682,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) MAG.T2.48_00295 1142394.PSMK_23290 7.8e-35 154.8 Planctomycetes Bacteria 2J0D1@203682,COG0705@1,COG0705@2 NA|NA|NA S PFAM Rhomboid family MAG.T2.48_00296 1210884.HG799467_gene13297 2.3e-28 133.3 Planctomycetes ywmF Bacteria 2J04B@203682,COG1994@1,COG1994@2 NA|NA|NA S PFAM Peptidase family M50 MAG.T2.48_00297 1142394.PSMK_20630 7.1e-68 264.6 Planctomycetes ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IXBY@203682,COG1127@1,COG1127@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents, ATPase component MAG.T2.48_00298 1123242.JH636436_gene409 3.4e-12 79.3 Planctomycetes ycf22 ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IZS7@203682,COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents periplasmic component MAG.T2.48_00299 1142394.PSMK_15960 1.3e-15 90.1 Bacteria ko:K02557,ko:K11892 ko02030,ko02040,ko03070,map02030,map02040,map03070 M00334 ko00000,ko00001,ko00002,ko02000,ko02035,ko02044 1.A.30.1,3.A.23.1 Bacteria COG1360@1,COG1360@2 NA|NA|NA N Flagellar Motor Protein MAG.T2.48_00300 1142394.PSMK_18480 2.9e-63 249.6 Planctomycetes pilD 3.4.23.43 ko:K02236,ko:K02278,ko:K02506,ko:K02654,ko:K10966 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 2IZQ8@203682,COG1989@1,COG1989@2 NA|NA|NA NOU Bacterial Peptidase A24 N-terminal domain MAG.T2.48_00301 1336235.JAEG01000007_gene1586 8.4e-08 63.2 Rhizobiaceae xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1PTYQ@1224,2UFD6@28211,4BG4P@82115,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T2.48_00302 1123228.AUIH01000036_gene2803 7.3e-60 238.4 Oceanospirillales xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUA4@1224,1RNAZ@1236,1XIJ4@135619,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T2.48_00303 1142394.PSMK_22060 6.9e-170 604.4 Planctomycetes recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IX1Q@203682,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) MAG.T2.48_00304 756272.Plabr_3487 1.3e-38 166.8 Planctomycetes ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IYXY@203682,COG1136@1,COG1136@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, ATPase component MAG.T2.48_00305 886293.Sinac_4851 1e-36 161.4 Planctomycetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IY8W@203682,COG0577@1,COG0577@2 NA|NA|NA V Permease component MAG.T2.48_00306 756272.Plabr_2828 7.7e-08 64.7 Bacteria oapA 2.7.11.1 ko:K02451,ko:K03086,ko:K07268,ko:K08884 M00331 ko00000,ko00002,ko01000,ko01001,ko02044,ko03021 9.B.42 Bacteria COG3266@1,COG3266@2 NA|NA|NA GM domain, Protein MAG.T2.48_00307 575540.Isop_2647 1.3e-142 514.6 Planctomycetes Bacteria 2J1Z2@203682,COG2866@1,COG2866@2 NA|NA|NA M PFAM peptidase M14 carboxypeptidase A MAG.T2.48_00308 314230.DSM3645_22174 1.2e-98 367.1 Planctomycetes ko:K07007 ko00000 Bacteria 2IWW4@203682,COG2081@1,COG2081@2 NA|NA|NA S HI0933-like protein MAG.T2.48_00309 1142394.PSMK_26230 5.4e-74 285.4 Planctomycetes dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2IYAC@203682,COG2027@1,COG2027@2 NA|NA|NA M D-Ala-D-Ala carboxypeptidase 3 (S13) family MAG.T2.48_00310 1142394.PSMK_25710 1.1e-45 190.3 Planctomycetes scpA ko:K05896 ko00000,ko03036 Bacteria 2IZIR@203682,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves MAG.T2.48_00311 1142394.PSMK_25700 6.8e-67 261.2 Planctomycetes kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K02467,ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_1278,iAPECO1_1312.APECO1_3818,iECABU_c1320.ECABU_c29780,iECED1_1282.ECED1_3157,iECH74115_1262.ECH74115_4519,iECOK1_1307.ECOK1_3081,iECS88_1305.ECS88_2971,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSF_1195.SF2731,iSFxv_1172.SFxv_3550,iS_1188.S2922,iUTI89_1310.UTI89_C3070,iYL1228.KPN_03607,iZ_1308.Z4560,ic_1306.c3262 Bacteria 2IX0R@203682,COG0517@1,COG0517@2,COG0794@1,COG0794@2 NA|NA|NA M Belongs to the SIS family. GutQ KpsF subfamily MAG.T2.48_00312 1961.JOAK01000006_gene4526 1.2e-10 72.8 Actinobacteria Bacteria 2IHP9@201174,COG1366@1,COG1366@2 NA|NA|NA T Belongs to the anti-sigma-factor antagonist family MAG.T2.48_00314 1142394.PSMK_20940 2.9e-39 168.3 Planctomycetes Bacteria 2IZAH@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.48_00315 886293.Sinac_0736 3.3e-197 695.7 Planctomycetes MA20_43170 ko:K06911 ko00000 Bacteria 2IYAH@203682,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain MAG.T2.48_00316 395495.Lcho_2011 4.5e-19 102.8 unclassified Burkholderiales tlpA Bacteria 1KPJ0@119065,1MZ36@1224,2VTF7@28216,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.48_00317 760192.Halhy_4326 6.8e-22 112.1 Sphingobacteriia Bacteria 1IRSC@117747,4NKFI@976,COG0526@1,COG0526@2 NA|NA|NA CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T2.48_00318 429009.Adeg_0626 4.3e-66 258.8 Thermoanaerobacterales cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,249WC@186801,42F5V@68295,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family MAG.T2.48_00319 1142394.PSMK_24300 7.2e-74 285.0 Planctomycetes ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 2J39X@203682,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein MAG.T2.48_00320 1142394.PSMK_12400 8.3e-47 194.1 Planctomycetes pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2IXSF@203682,COG0284@1,COG0284@2 NA|NA|NA F Belongs to the OMP decarboxylase family. Type 2 subfamily MAG.T2.48_00321 1121957.ATVL01000006_gene3440 1.6e-29 136.0 Cytophagia yuxK Bacteria 47R74@768503,4NQ93@976,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 MAG.T2.48_00322 1142394.PSMK_27230 2.4e-24 118.2 Planctomycetes ko:K03593 ko00000,ko03029,ko03036 Bacteria 2J1DX@203682,COG3536@1,COG3536@2 NA|NA|NA S Protein of unknown function (DUF971) MAG.T2.48_00323 1121943.KB899998_gene1535 3.2e-14 85.1 Oceanospirillales ybgC-2 ko:K07107 ko00000,ko01000 Bacteria 1RI3X@1224,1SAHQ@1236,1XS7R@135619,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T2.48_00324 595460.RRSWK_02690 1.4e-31 144.8 Planctomycetes Bacteria 2J2E9@203682,COG1409@1,COG1409@2 NA|NA|NA S Concanavalin A-like lectin/glucanases superfamily MAG.T2.48_00326 1142394.PSMK_05610 1.4e-105 390.2 Planctomycetes manB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321 Bacteria 2IXRS@203682,COG1109@1,COG1109@2 NA|NA|NA G PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain MAG.T2.48_00327 1142394.PSMK_21340 9.9e-78 297.0 Planctomycetes rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IY9P@203682,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family MAG.T2.48_00328 1142394.PSMK_21350 1.4e-50 206.8 Planctomycetes tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2IZGM@203682,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome MAG.T2.48_00329 166318.Syn8016DRAFT_2250 8.3e-26 123.6 Synechococcus Bacteria 1GNES@1117,1H0UR@1129,COG0537@1,COG0537@2 NA|NA|NA FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases MAG.T2.48_00331 344747.PM8797T_27095 2e-16 91.7 Planctomycetes Bacteria 2J047@203682,COG1694@1,COG1694@2 NA|NA|NA S PFAM MazG nucleotide pyrophosphohydrolase MAG.T2.48_00334 1379270.AUXF01000007_gene961 1.8e-26 127.5 Bacteria Bacteria COG4099@1,COG4099@2 NA|NA|NA F phospholipase Carboxylesterase MAG.T2.48_00335 1123072.AUDH01000024_gene327 1.8e-148 532.7 Rhodospirillales phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1MV9Y@1224,2JQ32@204441,2TSDP@28211,COG0415@1,COG0415@2 NA|NA|NA L Belongs to the DNA photolyase family MAG.T2.48_00336 1242864.D187_010288 1.1e-73 283.5 Deltaproteobacteria ko:K07071 ko00000 Bacteria 1MUB4@1224,2WK6V@28221,42PQ2@68525,COG1090@1,COG1090@2,COG4276@1,COG4276@2 NA|NA|NA S Domain of unknown function (DUF1731) MAG.T2.48_00338 765420.OSCT_1855 9.8e-45 186.8 Chloroflexia gmhA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2G6QD@200795,375VE@32061,COG0279@1,COG0279@2 NA|NA|NA G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate MAG.T2.48_00341 1142394.PSMK_13560 9.2e-30 137.9 Planctomycetes tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 2IZDP@203682,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine MAG.T2.48_00344 1211813.CAPH01000023_gene1972 1.4e-19 103.2 Rikenellaceae ko:K03088 ko00000,ko03021 Bacteria 22UIK@171550,2FRYA@200643,4NIRG@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.48_00345 1142394.PSMK_03050 2e-35 156.4 Bacteria Bacteria COG5012@1,COG5012@2 NA|NA|NA T cobalamin binding MAG.T2.48_00346 1142394.PSMK_03070 2.5e-54 219.2 Planctomycetes menG 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYWE@203682,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) MAG.T2.48_00347 1142394.PSMK_31090 2.5e-52 212.6 Planctomycetes ko:K07045 ko00000 Bacteria 2IXTD@203682,COG2159@1,COG2159@2 NA|NA|NA S TIM-barrel fold MAG.T2.48_00349 525309.HMPREF0494_0770 2e-15 89.7 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T2.48_00350 73044.JNXP01000007_gene5135 3.7e-11 75.5 Actinobacteria Bacteria 2GKAG@201174,COG0494@1,COG0494@2 NA|NA|NA L nUDIX hydrolase MAG.T2.48_00351 1123242.JH636437_gene6092 2e-132 479.9 Planctomycetes ko:K03305 ko00000 2.A.17 Bacteria 2IYIT@203682,COG3104@1,COG3104@2 NA|NA|NA E COG3104 Dipeptide tripeptide permease MAG.T2.48_00352 441769.ABFU01000056_gene863 2.9e-117 429.1 Bacillus ydaH ko:K12942 ko00000 Bacteria 1TPDU@1239,1ZARX@1386,4HAWR@91061,COG2978@1,COG2978@2 NA|NA|NA H AbgT putative transporter family MAG.T2.48_00353 266117.Rxyl_2540 1.5e-116 427.2 Rubrobacteria yyaL ko:K06888 ko00000 Bacteria 2GJ88@201174,4CPJ8@84995,COG1331@1,COG1331@2 NA|NA|NA O Protein of unknown function, DUF255 MAG.T2.48_00354 639283.Snov_3656 6.2e-93 348.2 Xanthobacteraceae 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1QTZP@1224,2U1G2@28211,3EZ3J@335928,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T2.48_00355 502025.Hoch_6846 1.2e-102 380.2 Myxococcales pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2667 Bacteria 1MU60@1224,2WJET@28221,2YV42@29,42MGN@68525,COG0077@1,COG0077@2,COG1605@1,COG1605@2 NA|NA|NA E Prephenate dehydratase MAG.T2.48_00357 1463936.JOJI01000002_gene2996 8.1e-124 450.7 Actinobacteria lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T2.48_00358 1288079.AUKN01000005_gene4931 9.6e-08 63.5 Actinobacteria Bacteria 2ISCU@201174,COG3832@1,COG3832@2 NA|NA|NA S Activator of hsp90 atpase 1 family protein MAG.T2.48_00360 290400.Jann_2234 2e-18 99.4 Alphaproteobacteria pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1MZJA@1224,2UGK6@28211,COG1267@1,COG1267@2 NA|NA|NA I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) MAG.T2.48_00361 1142394.PSMK_20830 7.8e-40 170.6 Planctomycetes 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2IZQ1@203682,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T2.48_00362 1142394.PSMK_15530 3.5e-26 125.9 Planctomycetes nuoJ 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2J0MC@203682,COG0839@1,COG0839@2 NA|NA|NA C PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 MAG.T2.48_00363 1142394.PSMK_15520 8.2e-25 119.8 Planctomycetes nuoK 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2J0GU@203682,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_00364 1142394.PSMK_15510 3.6e-127 462.6 Planctomycetes nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341,ko:K12137 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Bacteria 2IX10@203682,COG1009@1,COG1009@2 NA|NA|NA CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 MAG.T2.48_00365 926569.ANT_08410 2e-108 399.8 Chloroflexi nuoM 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2G5VU@200795,COG1008@1,COG1008@2 NA|NA|NA C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M MAG.T2.48_00366 1142394.PSMK_15490 1.2e-81 310.8 Planctomycetes nuoN 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IXC6@203682,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_00369 1142394.PSMK_14220 3.4e-144 518.8 Planctomycetes ko:K02347 ko00000,ko03400 Bacteria 2IWW1@203682,COG1387@1,COG1387@2,COG1796@1,COG1796@2 NA|NA|NA L DNA polymerase MAG.T2.48_00370 1142394.PSMK_23910 5.1e-43 181.8 Planctomycetes guaA2 6.3.5.2 ko:K01951,ko:K07065 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2J0QU@203682,COG0518@1,COG0518@2 NA|NA|NA F Glutamine amidotransferase class-I MAG.T2.48_00371 1142394.PSMK_25040 2.5e-16 93.6 Bacteria Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity MAG.T2.48_00372 1142394.PSMK_21090 1.7e-13 82.8 Planctomycetes Bacteria 2EAFJ@1,2J12W@203682,334IY@2 NA|NA|NA S Domain of unknown function (DUF1844) MAG.T2.48_00373 1476973.JMMB01000007_gene717 1.2e-34 154.1 Peptostreptococcaceae ubiA Bacteria 1TRTB@1239,24AQ0@186801,25SQ4@186804,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T2.48_00374 583355.Caka_1070 7.1e-59 234.2 Opitutae ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 3K7NP@414999,46SQ2@74201,COG1692@1,COG1692@2 NA|NA|NA S YmdB-like protein MAG.T2.48_00377 1392490.JHZX01000001_gene628 2.9e-47 196.8 Flavobacteriia Bacteria 1I1YW@117743,4PKTY@976,COG3291@1,COG3291@2 NA|NA|NA S ASPIC and UnbV MAG.T2.48_00378 349124.Hhal_1388 6.4e-230 804.7 Chromatiales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 1MUEQ@1224,1RMU1@1236,1WWGW@135613,COG1643@1,COG1643@2 NA|NA|NA L TIGRFAM ATP-dependent helicase HrpA MAG.T2.48_00381 1142394.PSMK_07250 3.4e-215 755.4 Planctomycetes polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2IXQR@203682,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity MAG.T2.48_00382 1142394.PSMK_32030 1.1e-50 207.6 Planctomycetes glmU 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXBV@203682,COG1207@1,COG1207@2 NA|NA|NA M Sugar nucleotidyl transferase MAG.T2.48_00385 1142394.PSMK_14530 1.8e-150 538.9 Planctomycetes mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 2IXSJ@203682,COG1077@1,COG1077@2 NA|NA|NA D COG1077 Actin-like ATPase involved in cell morphogenesis MAG.T2.48_00388 575540.Isop_3432 3.7e-41 177.2 Planctomycetes lnt ko:K03820 ko00000,ko01000 GT2 Bacteria 2IWUW@203682,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins MAG.T2.48_00389 1142394.PSMK_10710 1.4e-94 352.8 Planctomycetes accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016020,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0034645,GO:0042546,GO:0042759,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,5.4.99.2,6.4.1.2 ko:K01849,ko:K01962,ko:K01963 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00375,M00376,M00741 R00742,R00833,R04386 RC00040,RC00253,RC00367,RC00395 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS20740,iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 2IXWA@203682,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA MAG.T2.48_00390 1142394.PSMK_28270 9.2e-50 203.8 Planctomycetes rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZKC@203682,COG0036@1,COG0036@2 NA|NA|NA G TIGRFAM Ribulose-phosphate 3-epimerase MAG.T2.48_00391 661478.OP10G_2991 6e-24 118.6 Bacteria msrB 1.8.4.11,1.8.4.12,3.5.1.104 ko:K12267,ko:K22278 ko00000,ko01000 Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis MAG.T2.48_00392 314230.DSM3645_15640 4.6e-102 378.3 Planctomycetes pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSbBS512_1146.SbBS512_E3351 Bacteria 2IYIS@203682,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family MAG.T2.48_00393 1142394.PSMK_18690 5.6e-66 258.1 Planctomycetes miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2IYY6@203682,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) MAG.T2.48_00394 391625.PPSIR1_02913 1.5e-281 975.7 Myxococcales topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1MUFZ@1224,2WJTT@28221,2YU14@29,42MM9@68525,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone MAG.T2.48_00395 671143.DAMO_0971 1.8e-11 75.1 Bacteria Bacteria COG2002@1,COG2002@2 NA|NA|NA K toxin-antitoxin pair type II binding MAG.T2.48_00396 1125863.JAFN01000001_gene3475 5.4e-12 77.8 Deltaproteobacteria Bacteria 1Q9X7@1224,2WT2V@28221,42X9V@68525,COG1569@1,COG1569@2 NA|NA|NA S PIN domain MAG.T2.48_00400 344747.PM8797T_26345 1.4e-59 237.3 Planctomycetes ko:K05820 ko00000,ko02000 2.A.1.27 Bacteria 2J534@203682,COG0477@1,COG2814@2 NA|NA|NA EGP MFS_1 like family MAG.T2.48_00401 1142394.PSMK_05790 1e-160 573.2 Planctomycetes ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2IXN9@203682,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate MAG.T2.48_00403 754477.Q7C_660 4.6e-37 161.4 Thiotrichales pqiA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03808 ko00000 Bacteria 1MWG1@1224,1RM9Z@1236,462EX@72273,COG2995@1,COG2995@2 NA|NA|NA S paraquat-inducible protein A MAG.T2.48_00404 382464.ABSI01000017_gene13 6e-46 191.4 Verrucomicrobiae yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 ko:K06192 ko00000 Bacteria 2ITG5@203494,46V6H@74201,COG3008@1,COG3008@2 NA|NA|NA Q MlaD protein MAG.T2.48_00405 1340493.JNIF01000003_gene1293 3.8e-25 123.2 Acidobacteria rsbU 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315,ko:K11894,ko:K11913 ko00230,ko02025,ko03070,ko04113,ko04213,map00230,map02025,map03070,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02044,ko03021 3.A.23.1 Bacteria 3Y4DC@57723,COG1716@1,COG1716@2,COG2203@1,COG2203@2,COG2208@1,COG2208@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain MAG.T2.48_00406 240016.ABIZ01000001_gene4518 9.4e-14 85.1 Verrucomicrobiae Bacteria 28I0W@1,2IUKF@203494,30QX6@2,46WYN@74201 NA|NA|NA MAG.T2.48_00407 589865.DaAHT2_1555 3.6e-24 118.6 Deltaproteobacteria exbB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 1QNJ1@1224,2WUI6@28221,42YY2@68525,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel MAG.T2.48_00408 1142394.PSMK_27640 1.8e-58 233.0 Planctomycetes ispA GO:0003674,GO:0003824,GO:0004161,GO:0004311,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 iPC815.YPO3176,iSFV_1184.SFV_0386 Bacteria 2IX56@203682,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T2.48_00409 1142394.PSMK_27630 4e-204 718.0 Planctomycetes dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYHC@203682,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) MAG.T2.48_00410 319225.Plut_0086 6.2e-18 98.6 Bacteria Bacteria COG1462@1,COG1462@2 NA|NA|NA M curli production assembly transport component CsgG MAG.T2.48_00411 1111728.ATYS01000017_gene3165 5.9e-14 84.7 Gammaproteobacteria ko:K07337 ko00000 Bacteria 1R5KN@1224,1S3MQ@1236,COG3417@1,COG3417@2 NA|NA|NA M COG3417 Collagen-binding surface adhesin SpaP (antigen I II family) MAG.T2.48_00413 1142394.PSMK_24700 7.7e-24 118.6 Bacteria ko:K09859 ko00000 Bacteria COG3014@1,COG3014@2 NA|NA|NA S protein conserved in bacteria MAG.T2.48_00414 1142394.PSMK_30760 4.3e-142 511.5 Planctomycetes ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2IXSC@203682,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY MAG.T2.48_00415 472759.Nhal_2852 9.1e-33 148.3 Bacteria tqsA ko:K03548 ko00000,ko02000 2.A.86.1 Bacteria COG0628@1,COG0628@2 NA|NA|NA D permease MAG.T2.48_00416 1142394.PSMK_01480 1.4e-25 122.9 Planctomycetes Bacteria 2E5IJ@1,2J0P5@203682,3309Y@2 NA|NA|NA MAG.T2.48_00417 27679.XP_010337237.1 1.1e-38 166.8 Primates MPG GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0031974,GO:0031981,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045007,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Mammalia 35CEZ@314146,39RQW@33154,3BA2R@33208,3D02F@33213,3JFKA@40674,488EB@7711,4900A@7742,4M72V@9443,COG2094@1,KOG4486@2759 NA|NA|NA L glycosylase MAG.T2.48_00418 1142394.PSMK_02450 5.1e-41 175.6 Planctomycetes ssnA 3.5.4.40 ko:K20810 ko00130,ko01110,map00130,map01110 R10695 RC00477 ko00000,ko00001,ko01000 Bacteria 2IYVP@203682,COG0402@1,COG0402@2 NA|NA|NA F COG0402 Cytosine deaminase and related metal-dependent MAG.T2.48_00419 1142394.PSMK_04800 2.2e-29 136.3 Planctomycetes ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 2J1IS@203682,COG1360@1,COG1360@2 NA|NA|NA N Flagellar motor protein MAG.T2.48_00420 382464.ABSI01000012_gene2217 5.5e-51 209.9 Bacteria Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.48_00421 1142394.PSMK_01460 4e-52 211.5 Planctomycetes mlaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IX01@203682,COG0767@1,COG0767@2 NA|NA|NA Q Belongs to the MlaE permease family MAG.T2.48_00422 1125863.JAFN01000001_gene3370 3.3e-07 63.2 Deltaproteobacteria Bacteria 1MY5V@1224,2WJUM@28221,42M7B@68525,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues MAG.T2.48_00424 502025.Hoch_6539 3.3e-46 194.9 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.48_00427 575540.Isop_0606 2.6e-39 168.7 Planctomycetes Bacteria 2J0ZX@203682,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) MAG.T2.48_00429 583355.Caka_1959 1.6e-34 152.5 Verrucomicrobia 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 46V63@74201,COG1225@1,COG1225@2 NA|NA|NA O Redoxin MAG.T2.48_00430 1223410.KN050846_gene39 4.7e-24 120.2 Flavobacteriia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1IJKK@117743,4NQIZ@976,COG1404@1,COG1404@2,COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.48_00431 502025.Hoch_6539 9.7e-39 168.7 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.48_00432 1254432.SCE1572_22375 4.7e-18 99.8 Myxococcales 3.4.21.50,3.4.24.25 ko:K01337,ko:K08604,ko:K20276 ko02024,ko05110,ko05111,map02024,map05110,map05111 ko00000,ko00001,ko01000,ko01002 Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2,COG3227@1,COG3227@2,COG4412@1,COG4412@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.48_00433 1142394.PSMK_05000 5.1e-129 468.0 Planctomycetes 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2IZ5X@203682,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T2.48_00436 321327.CYA_0818 3.4e-95 355.5 Synechococcus cefD 5.1.1.17 ko:K04127,ko:K11325,ko:K21174 ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130 M00673,M00825 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1G2M5@1117,1GYYM@1129,COG0520@1,COG0520@2 NA|NA|NA E L-cysteine cystine lyase MAG.T2.48_00437 1142394.PSMK_19750 2.5e-46 192.2 Planctomycetes lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2IZCV@203682,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair MAG.T2.48_00438 1142394.PSMK_15810 6.9e-47 194.5 Planctomycetes trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWYG@203682,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate MAG.T2.48_00440 530564.Psta_3926 1.5e-17 98.6 Planctomycetes 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IZ5Z@203682,COG0265@1,COG0265@2 NA|NA|NA O COG0265 Trypsin-like serine proteases, typically periplasmic MAG.T2.48_00441 1142394.PSMK_15730 0.0 1171.8 Planctomycetes Bacteria 2IXIT@203682,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane MAG.T2.48_00444 575540.Isop_3081 3.8e-54 218.0 Planctomycetes Bacteria 2J4YK@203682,COG0526@1,COG0526@2 NA|NA|NA O Redoxin MAG.T2.48_00445 1121939.L861_01770 7.7e-22 110.9 Oceanospirillales Bacteria 1R6F0@1224,1RXR4@1236,1XQKX@135619,COG0500@1,COG2226@2 NA|NA|NA Q Methionine biosynthesis protein MetW MAG.T2.48_00446 1173027.Mic7113_1275 1.2e-30 140.2 Oscillatoriales Bacteria 1G57N@1117,1HAU7@1150,COG0500@1,COG0500@2 NA|NA|NA Q Tellurite resistance protein TehB MAG.T2.48_00447 497964.CfE428DRAFT_6330 4e-52 211.5 Verrucomicrobia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 46Z7C@74201,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T2.48_00449 1142394.PSMK_00990 1.7e-94 353.6 Planctomycetes gltX 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2IXD6@203682,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) MAG.T2.48_00451 1487953.JMKF01000028_gene1341 3e-79 302.4 Oscillatoriales corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1G1AG@1117,1H99G@1150,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions MAG.T2.48_00452 756272.Plabr_1905 3.9e-196 691.0 Planctomycetes chlI 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 R03877 RC01012 ko00000,ko00001,ko01000 iNJ661.Rv0958 Bacteria 2IXX1@203682,COG1239@1,COG1239@2 NA|NA|NA H COG1239 Mg-chelatase subunit ChlI MAG.T2.48_00453 344747.PM8797T_16353 1.1e-184 653.3 Planctomycetes GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IXJD@203682,COG4867@1,COG4867@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.48_00454 1121035.AUCH01000007_gene448 6.9e-44 186.8 Rhodocyclales Bacteria 1MUME@1224,2KV0V@206389,2VIKY@28216,COG2982@1,COG2982@2 NA|NA|NA M Domain of Unknown Function (DUF748) MAG.T2.48_00455 1210884.HG799462_gene8941 1.2e-222 779.6 Planctomycetes glnN 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2IXF6@203682,COG3968@1,COG3968@2 NA|NA|NA S Glutamine synthetase type III MAG.T2.48_00456 1142394.PSMK_15390 1.9e-65 256.9 Planctomycetes tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 2IXGD@203682,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase MAG.T2.48_00458 1142394.PSMK_15370 7.2e-156 557.0 Planctomycetes clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2IXDS@203682,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP MAG.T2.48_00459 1279015.KB908464_gene2106 1.2e-11 76.6 Aeromonadales yebR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0033745,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1RDBM@1224,1S6QU@1236,1Y4JV@135624,COG1956@1,COG1956@2 NA|NA|NA T GAF domain MAG.T2.48_00460 1142394.PSMK_08500 8.2e-15 86.3 Planctomycetes rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0SS@203682,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family MAG.T2.48_00461 1142394.PSMK_08510 1.4e-106 394.0 Planctomycetes dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2IXQ4@203682,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication MAG.T2.48_00462 1142394.PSMK_08520 1.2e-178 633.3 Planctomycetes rpoD ko:K03086 ko00000,ko03021 Bacteria 2IXI3@203682,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T2.48_00464 1128421.JAGA01000002_gene41 1.1e-148 533.9 unclassified Bacteria 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2NQRG@2323,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.48_00465 886293.Sinac_6283 7.4e-12 77.8 Planctomycetes Bacteria 2EDV6@1,2J12E@203682,337QB@2 NA|NA|NA MAG.T2.48_00467 886293.Sinac_6281 3.6e-260 905.2 Planctomycetes ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2IXPG@203682,COG1196@1,COG1196@2,COG1674@1,COG1674@2 NA|NA|NA D DNA segregation ATPase FtsK SpoIIIE MAG.T2.48_00468 1267533.KB906733_gene3472 1.3e-74 288.5 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_00469 1267535.KB906767_gene4499 5.3e-32 144.4 Acidobacteriia ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2JJS7@204432,3Y589@57723,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.48_00471 195250.CM001776_gene2903 3e-34 154.1 Cyanobacteria Bacteria 1GDRV@1117,COG0729@1,COG0729@2 NA|NA|NA M surface antigen MAG.T2.48_00472 195250.CM001776_gene2903 3.5e-36 160.2 Cyanobacteria Bacteria 1GDRV@1117,COG0729@1,COG0729@2 NA|NA|NA M surface antigen MAG.T2.48_00473 1125863.JAFN01000001_gene752 2.1e-21 108.6 Deltaproteobacteria Bacteria 1N2JS@1224,2WQ4M@28221,42TR3@68525,COG1917@1,COG1917@2 NA|NA|NA S PFAM Cupin 2, conserved barrel domain protein MAG.T2.48_00474 1210884.HG799464_gene10660 3.6e-50 206.1 Planctomycetes rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2IY8T@203682,COG0349@1,COG0349@2 NA|NA|NA J COG0349 Ribonuclease D MAG.T2.48_00475 452637.Oter_1495 2.4e-09 68.2 Opitutae ko:K09131 ko00000 Bacteria 3K8CC@414999,46T9T@74201,COG1872@1,COG1872@2 NA|NA|NA S DUF167 MAG.T2.48_00476 1142394.PSMK_29910 1.3e-162 579.7 Planctomycetes uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2IWVR@203682,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision MAG.T2.48_00478 478741.JAFS01000001_gene1984 5e-110 404.8 unclassified Verrucomicrobia pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 37GCS@326457,46S78@74201,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily MAG.T2.48_00479 243233.MCA2161 1.3e-125 457.6 Gammaproteobacteria ko:K03615,ko:K09690 ko02010,map02010 M00250 ko00000,ko00001,ko00002,ko02000 3.A.1.103 Bacteria 1QX0J@1224,1RZ5A@1236,COG3206@1,COG3206@2 NA|NA|NA M protein involved in exopolysaccharide biosynthesis MAG.T2.48_00480 575540.Isop_1665 1.8e-19 103.6 Bacteria Bacteria COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) MAG.T2.48_00481 338963.Pcar_2082 5.9e-97 362.5 Deltaproteobacteria hpnN ko:K07003 ko00000 Bacteria 1QX46@1224,2WKGH@28221,42QK9@68525,COG4258@1,COG4258@2 NA|NA|NA S MMPL family MAG.T2.48_00482 1246474.ANBE01000003_gene2073 1.3e-07 63.2 Streptosporangiales Bacteria 2GQK5@201174,4EKNK@85012,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain MAG.T2.48_00483 1142394.PSMK_20750 7.2e-48 198.0 Planctomycetes nrnA GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 ko:K00974,ko:K06881 ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013 R00188,R00508,R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 2IYQ0@203682,COG0618@1,COG0618@2 NA|NA|NA S phosphoesterase RecJ domain protein MAG.T2.48_00484 1142394.PSMK_20760 9.1e-58 230.7 Planctomycetes ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYZQ@203682,COG0196@1,COG0196@2 NA|NA|NA H riboflavin biosynthesis protein MAG.T2.48_00485 502025.Hoch_4376 1.5e-239 836.3 Deltaproteobacteria glnD 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371 ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020 M00017,M00018 R00243,R01773,R01775 RC00006,RC00087,RC02799 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXNV@1224,2WJWV@28221,42KZZ@68525,COG2844@1,COG2844@2,COG2902@1,COG2902@2 NA|NA|NA E PFAM Glu Leu Phe Val dehydrogenase MAG.T2.48_00487 652103.Rpdx1_2631 2e-74 285.8 Bradyrhizobiaceae 2.1.1.228 ko:K15429 R00597 RC00003,RC00334 ko00000,ko01000,ko03016 Bacteria 1N43N@1224,2UDB4@28211,3JXB9@41294,COG2520@1,COG2520@2 NA|NA|NA J Methyltransferase fkbm family MAG.T2.48_00488 1541065.JRFE01000007_gene5114 6e-14 84.7 Pleurocapsales Bacteria 1GKIS@1117,2DIHB@1,303AH@2,3VNCG@52604 NA|NA|NA MAG.T2.48_00489 1283300.ATXB01000001_gene387 3.9e-104 385.2 Gammaproteobacteria Bacteria 1NT1Q@1224,1RP9M@1236,COG1752@1,COG1752@2 NA|NA|NA S esterase of the alpha-beta hydrolase superfamily MAG.T2.48_00490 1283300.ATXB01000001_gene387 9.5e-96 357.5 Gammaproteobacteria Bacteria 1NT1Q@1224,1RP9M@1236,COG1752@1,COG1752@2 NA|NA|NA S esterase of the alpha-beta hydrolase superfamily MAG.T2.48_00491 1210884.HG799465_gene11874 1e-36 161.8 Planctomycetes Bacteria 2IZ9P@203682,COG5316@1,COG5316@2 NA|NA|NA S N-terminal domain of unknown function (DUF4140) MAG.T2.48_00494 1158760.AQXP01000054_gene1634 2.2e-55 222.6 Chromatiales 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVXG@1224,1S4GS@1236,1WY88@135613,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family MAG.T2.48_00495 997346.HMPREF9374_3302 6.7e-91 340.9 Thermoactinomycetaceae Bacteria 1TPJT@1239,27AW7@186824,4H9KJ@91061,COG1082@1,COG1082@2 NA|NA|NA G AP endonuclease family 2 C terminus MAG.T2.48_00498 1122603.ATVI01000007_gene1552 1.3e-53 217.2 Xanthomonadales queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1MV1H@1224,1RMD9@1236,1X3CD@135614,COG1600@1,COG1600@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) MAG.T2.48_00499 240015.ACP_0812 2.9e-79 302.8 Acidobacteriia crtQ 1.17.8.1,1.3.5.5,1.3.5.6 ko:K00514,ko:K02293,ko:K21677 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R04786,R04787,R04798,R04800,R07510,R07511,R09652,R09653,R09654,R09656,R09658 RC01214,RC01958,RC01959,RC03092,RC03093 ko00000,ko00001,ko00002,ko01000 Bacteria 2JIW6@204432,3Y3PB@57723,COG3349@1,COG3349@2 NA|NA|NA C FAD dependent oxidoreductase MAG.T2.48_00500 1267535.KB906767_gene2365 3.3e-44 185.7 Acidobacteriia 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2JIHF@204432,3Y3YX@57723,COG1562@1,COG1562@2 NA|NA|NA I PFAM Squalene phytoene synthase MAG.T2.48_00501 1123508.JH636442_gene4304 8e-60 237.7 Planctomycetes hpnC 2.5.1.32,2.5.1.99,4.2.3.156 ko:K02291,ko:K21679 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IXUP@203682,COG1562@1,COG1562@2 NA|NA|NA I Squalene phytoene synthase MAG.T2.48_00502 1142394.PSMK_10290 7.8e-89 334.7 Planctomycetes rpoN ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 2IXGU@203682,COG1508@1,COG1508@2 NA|NA|NA K rna polymerase sigma-54 factor MAG.T2.48_00503 247490.KSU1_D0338 9.5e-50 203.8 Planctomycetes recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2IXK5@203682,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO MAG.T2.48_00504 886293.Sinac_6467 3e-62 246.1 Planctomycetes pliT Bacteria 2IXF3@203682,COG4956@1,COG4956@2 NA|NA|NA S Integral membrane protein (PIN domain superfamily) MAG.T2.48_00505 1142394.PSMK_05840 1.1e-98 367.5 Planctomycetes dnaX 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IX1M@203682,COG2812@1,COG2812@2 NA|NA|NA H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity MAG.T2.48_00506 1142394.PSMK_21660 2e-82 313.5 Planctomycetes flgE GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IYJT@203682,COG1749@1,COG1749@2 NA|NA|NA N Flagellar hook protein FlgE MAG.T2.48_00507 595460.RRSWK_05641 4.4e-11 74.7 Planctomycetes flgD GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2J0QK@203682,COG1843@1,COG1843@2 NA|NA|NA N Flagellar hook capping protein MAG.T2.48_00510 1142394.PSMK_21710 9.6e-107 394.0 Planctomycetes fliI 3.6.3.14 ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 2IXTN@203682,COG1157@1,COG1157@2 NA|NA|NA NU COG1157 Flagellar biosynthesis type III secretory pathway MAG.T2.48_00511 521674.Plim_3097 2.5e-07 62.8 Planctomycetes fliH ko:K02411,ko:K03223 ko02040,ko03070,map02040,map03070 M00332,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2J151@203682,COG1317@1,COG1317@2 NA|NA|NA N COG1317 Flagellar biosynthesis type III secretory pathway protein MAG.T2.48_00512 1142394.PSMK_21730 4.4e-101 374.8 Planctomycetes fliG GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006935,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0046982,GO:0046983,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0071978,GO:0097588 ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 Bacteria 2IX0X@203682,COG1536@1,COG1536@2 NA|NA|NA N flagellar motor switch protein MAG.T2.48_00513 1142394.PSMK_21740 8.5e-38 165.2 Planctomycetes fliF ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 2IYWW@203682,COG1766@1,COG1766@2 NA|NA|NA N Flagellar biosynthesis type III secretory pathway MAG.T2.48_00514 1142394.PSMK_21750 1.4e-16 92.4 Planctomycetes fliE ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2J1P2@203682,COG1677@1,COG1677@2 NA|NA|NA N Flagellar hook-basal body complex protein FliE MAG.T2.48_00515 1142394.PSMK_21760 1.5e-20 105.9 Planctomycetes flgC ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2J09G@203682,COG1558@1,COG1558@2 NA|NA|NA N Belongs to the flagella basal body rod proteins family MAG.T2.48_00516 1142394.PSMK_21770 7.3e-23 113.6 Planctomycetes flgB GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2J0V3@203682,COG1815@1,COG1815@2 NA|NA|NA N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body MAG.T2.48_00517 1142394.PSMK_21780 4.9e-111 408.3 Planctomycetes atoC ko:K07713,ko:K07714,ko:K10943 ko02020,ko05111,map02020,map05111 M00499,M00500,M00515 ko00000,ko00001,ko00002,ko02022 Bacteria 2IXMN@203682,COG2204@1,COG2204@2 NA|NA|NA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains MAG.T2.48_00518 1142394.PSMK_21790 9.3e-37 161.0 Planctomycetes bamV 2.7.13.3 ko:K07710,ko:K10125 ko02020,map02020 M00500,M00504 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IZJ4@203682,COG4191@1,COG4191@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T2.48_00523 595460.RRSWK_04112 6.9e-10 70.9 Planctomycetes Bacteria 2BWMY@1,2J0M4@203682,331GB@2 NA|NA|NA MAG.T2.48_00524 1142394.PSMK_18500 1.7e-49 203.4 Planctomycetes dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 2IZSP@203682,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria MAG.T2.48_00526 926569.ANT_07690 6.9e-112 411.0 Chloroflexi tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2G64J@200795,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) MAG.T2.48_00527 344747.PM8797T_13922 6.1e-106 391.0 Planctomycetes tal 1.1.1.343,1.1.1.44,2.2.1.2 ko:K00033,ko:K00616 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00006,M00007 R01528,R01827,R10221 RC00001,RC00439,RC00539,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY2M@203682,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway MAG.T2.48_00528 383372.Rcas_0710 7.6e-204 716.8 Chloroflexia pgi 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2G5ZM@200795,376U7@32061,COG0166@1,COG0166@2 NA|NA|NA F glucose-6-phosphate isomerase activity MAG.T2.48_00529 883.DvMF_2659 4.6e-89 335.1 Desulfovibrionales nifS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1MU1C@1224,2M92B@213115,2WIR6@28221,42M5V@68525,COG1104@1,COG1104@2 NA|NA|NA E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine MAG.T2.48_00532 1142394.PSMK_01740 2e-133 482.6 Planctomycetes recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2IX4U@203682,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage MAG.T2.48_00534 314230.DSM3645_06971 5e-140 504.2 Planctomycetes uxs 4.1.1.35,4.2.1.46 ko:K01710,ko:K08678 ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00793 R01384,R06513 RC00402,RC00508 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWW0@203682,COG0451@1,COG0451@2 NA|NA|NA GM NAD- dependent epimerase dehydratase MAG.T2.48_00535 502025.Hoch_3570 1.5e-71 278.1 Myxococcales 2.7.11.1 ko:K08884 ko00000,ko01000,ko01001 Bacteria 1MV1P@1224,2X5YN@28221,2YUEJ@29,42PPB@68525,COG0457@1,COG0457@2,COG0515@1,COG0515@2,COG2114@1,COG2114@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.48_00536 1142394.PSMK_23400 1.5e-52 213.8 Planctomycetes anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 ko:K07106,ko:K09001 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 Bacteria 2IWTZ@203682,COG2103@1,COG2103@2,COG2377@1,COG2377@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate MAG.T2.48_00537 338963.Pcar_0653 1.1e-63 250.0 Desulfuromonadales Bacteria 1MY2Z@1224,2WJPD@28221,42MP1@68525,43S7H@69541,COG0745@1,COG0745@2 NA|NA|NA T cheY-homologous receiver domain MAG.T2.48_00538 880072.Desac_2637 8.6e-72 277.7 Syntrophobacterales phoR 2.7.13.3 ko:K02484,ko:K07636,ko:K07768 ko02020,map02020 M00434,M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWF3@1224,2MQCA@213462,2WJGX@28221,42NB5@68525,COG5002@1,COG5002@2 NA|NA|NA T Signal transduction histidine kinase MAG.T2.48_00539 265072.Mfla_0795 3.5e-87 328.6 Nitrosomonadales pstS GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0016020,GO:0042301,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051234,GO:0071944 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MUH9@1224,2KMCK@206350,2VKAU@28216,COG0226@1,COG0226@2 NA|NA|NA P TIGRFAM phosphate binding protein MAG.T2.48_00540 1122927.KB895414_gene5154 1.1e-71 277.3 Paenibacillaceae pstC ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,26SNZ@186822,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane MAG.T2.48_00541 1473546.CH76_01720 4e-69 268.9 Lysinibacillus pstA ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3IXF2@400634,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease MAG.T2.48_00542 595460.RRSWK_02797 3.8e-103 381.3 Planctomycetes pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 2IWRV@203682,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system MAG.T2.48_00543 1499967.BAYZ01000068_gene1924 4.2e-33 148.3 unclassified Bacteria phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 ko:K02039 ko00000 Bacteria 2NPWX@2323,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake MAG.T2.48_00544 456442.Mboo_1563 1.4e-13 83.2 Methanomicrobia aroE GO:0003674,GO:0003824,GO:0004764,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0055114,GO:0071704,GO:1901576,GO:1901615 1.1.1.25,2.7.1.71,4.2.1.10 ko:K00014,ko:K00891,ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R02413,R03084 RC00002,RC00078,RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 iAF692.Mbar_A0923 Archaea 2N9IF@224756,2XV7K@28890,COG0169@1,COG0703@1,arCOG01033@2157,arCOG01047@2157 NA|NA|NA F Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) MAG.T2.48_00545 756272.Plabr_2104 6.5e-53 214.5 Planctomycetes rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2IYW1@203682,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism MAG.T2.48_00547 1142394.PSMK_14590 3.2e-53 215.7 Planctomycetes uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2J02W@203682,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin MAG.T2.48_00549 1145276.T479_20845 5.4e-159 568.2 Lysinibacillus ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3IX45@400634,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T2.48_00550 1123508.JH636440_gene2397 8.4e-23 112.8 Planctomycetes Bacteria 2J0RB@203682,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family MAG.T2.48_00551 1142394.PSMK_13110 6.8e-66 257.7 Planctomycetes 5.1.3.35 ko:K19974 ko00525,ko01130,map00525,map01130 M00814 R11081 RC01519 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXZ6@203682,COG1082@1,COG1082@2 NA|NA|NA G isomerase MAG.T2.48_00552 1142394.PSMK_03830 1.7e-38 166.4 Bacteria Bacteria 2EDBD@1,3377P@2 NA|NA|NA MAG.T2.48_00553 388399.SSE37_10462 3.4e-17 96.3 Proteobacteria Bacteria 1P1Z3@1224,2EVR7@1,33P56@2 NA|NA|NA MAG.T2.48_00554 1303518.CCALI_02907 1.2e-78 300.8 Bacteria Bacteria COG5267@1,COG5267@2 NA|NA|NA S Protein of unknown function (DUF1800) MAG.T2.48_00555 1210884.HG799465_gene11413 1.5e-82 313.5 Planctomycetes Bacteria 2IYGM@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T2.48_00557 1167006.UWK_01624 1.1e-136 493.8 Desulfobacterales ko:K03688 ko00000 Bacteria 1MU1Z@1224,2MHU5@213118,2WK1B@28221,42N87@68525,COG0661@1,COG0661@2 NA|NA|NA S pfam abc-1 MAG.T2.48_00560 497321.C664_06458 1.2e-08 67.4 Betaproteobacteria Bacteria 1N1BR@1224,2DN0A@1,2VVZG@28216,32UPR@2 NA|NA|NA MAG.T2.48_00561 1142394.PSMK_20780 7.1e-159 567.8 Planctomycetes dinG GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 2IX82@203682,COG1199@1,COG1199@2 NA|NA|NA KL helicase MAG.T2.48_00562 1142394.PSMK_01050 1.6e-36 159.8 Planctomycetes rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2J158@203682,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA MAG.T2.48_00563 1142394.PSMK_08130 1.2e-73 283.9 Planctomycetes rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2IZRI@203682,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T2.48_00564 1142394.PSMK_08120 4e-73 283.1 Planctomycetes 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 2IXAE@203682,COG0768@1,COG0768@2 NA|NA|NA M Penicillin binding protein transpeptidase domain MAG.T2.48_00566 1532557.JL37_29010 1.2e-110 406.4 Alcaligenaceae rocF GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 ko:K01476,ko:K01480 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00133,M00134 R00551,R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFH@1224,2VJU2@28216,3T1ZJ@506,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T2.48_00567 1142394.PSMK_24980 5.8e-89 334.7 Planctomycetes mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2IXU1@203682,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan MAG.T2.48_00568 404589.Anae109_3880 7.5e-62 245.0 Myxococcales murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1QTSF@1224,2WIJZ@28221,2YXRU@29,42MXF@68525,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein MAG.T2.48_00569 1142394.PSMK_05440 2.2e-94 353.2 Planctomycetes murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2158c Bacteria 2IWUT@203682,COG0769@1,COG0769@2 NA|NA|NA M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T2.48_00570 1121468.AUBR01000027_gene2878 1.7e-71 276.6 Thermoanaerobacterales queA 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1TPKD@1239,247NT@186801,42ETD@68295,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T2.48_00572 1142394.PSMK_29220 6.6e-59 234.6 Planctomycetes fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria 2IYU1@203682,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus MAG.T2.48_00574 794903.OPIT5_28330 2.1e-19 104.0 Opitutae ko:K11935 ko02026,map02026 ko00000,ko00001 Bacteria 3K7D2@414999,46V40@74201,COG0457@1,COG0457@2,COG4783@1,COG4783@2 NA|NA|NA S chaperone-mediated protein folding MAG.T2.48_00575 1232410.KI421421_gene3580 9.8e-58 230.3 Desulfuromonadales kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 Bacteria 1MUUU@1224,2WMQW@28221,42PTX@68525,43TY0@69541,COG1212@1,COG1212@2 NA|NA|NA M Cytidylyltransferase MAG.T2.48_00576 1254432.SCE1572_46520 8.2e-94 352.1 Myxococcales ape2 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUCI@1224,2WJ2C@28221,2YTZK@29,42KZI@68525,COG0308@1,COG0308@2,COG1413@1,COG1413@2 NA|NA|NA CE Peptidase family M1 domain MAG.T2.48_00577 1142394.PSMK_27420 1.5e-205 722.6 Planctomycetes pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2IXNE@203682,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates MAG.T2.48_00579 204773.HEAR0764 3.4e-48 198.0 Oxalobacteraceae eco GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0019538,GO:0030162,GO:0030234,GO:0030288,GO:0030313,GO:0030414,GO:0031323,GO:0031324,GO:0031975,GO:0032268,GO:0032269,GO:0042597,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044464,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0098772,GO:1901564 ko:K08276 ko00000 Bacteria 1MZEN@1224,2VUFF@28216,4773R@75682,COG4574@1,COG4574@2 NA|NA|NA S Ecotin MAG.T2.48_00580 1192034.CAP_8277 1.3e-48 201.4 Myxococcales ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1QZBM@1224,2WQPM@28221,2Z3I2@29,42TG7@68525,COG3266@1,COG3266@2 NA|NA|NA S FG-GAP repeat MAG.T2.48_00585 278957.ABEA03000206_gene3785 3.5e-35 154.8 Opitutae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 3K7ZG@414999,46SYZ@74201,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily MAG.T2.48_00588 1142394.PSMK_11940 4.9e-98 364.8 Planctomycetes mrp ko:K03593 ko00000,ko03029,ko03036 Bacteria 2IXIF@203682,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP MAG.T2.48_00589 530564.Psta_4382 1.3e-123 449.9 Planctomycetes kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 2IX0H@203682,COG0156@1,COG0156@2 NA|NA|NA H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA MAG.T2.48_00590 926569.ANT_16550 9.4e-104 383.6 Chloroflexi ltd 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 2G8B1@200795,COG0451@1,COG0451@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T2.48_00593 1298858.AUEL01000004_gene939 5.2e-15 88.2 Phyllobacteriaceae lpxE 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 1N7CW@1224,2TRDP@28211,43M78@69277,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues MAG.T2.48_00594 768671.ThimaDRAFT_2134 3.3e-77 296.2 Chromatiales ynaI ko:K16052 ko00000,ko02000 1.A.23.4 Bacteria 1MXD2@1224,1RNUB@1236,1WXY4@135613,COG0668@1,COG0668@2 NA|NA|NA M PFAM Mechanosensitive ion channel MAG.T2.48_00595 493475.GARC_1198 7.1e-24 117.9 Proteobacteria Bacteria 1NHMM@1224,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain MAG.T2.48_00596 886293.Sinac_4302 3.5e-63 248.4 Planctomycetes 2.7.11.1 ko:K11904,ko:K12132,ko:K20276 ko02024,ko03070,map02024,map03070 M00334 ko00000,ko00001,ko00002,ko01000,ko01001,ko02044 3.A.23.1 Bacteria 2IZVN@203682,COG3266@1,COG3266@2,COG4655@1,COG4655@2,COG4932@1,COG4932@2 NA|NA|NA M Protein of unknown function (DUF3494) MAG.T2.48_00600 1123242.JH636435_gene3026 4.6e-18 100.1 Planctomycetes Bacteria 2IZ04@203682,COG1413@1,COG1413@2 NA|NA|NA C GGDEF domain MAG.T2.48_00601 933262.AXAM01000156_gene1041 3e-16 92.8 Deltaproteobacteria Bacteria 1NUIA@1224,2DV5M@1,2WV1Z@28221,33U68@2,42ZFX@68525 NA|NA|NA MAG.T2.48_00602 886293.Sinac_6222 8.6e-07 61.2 Planctomycetes ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2J4VP@203682,COG2165@1,COG2165@2 NA|NA|NA NU Protein of unknown function (DUF1559) MAG.T2.48_00603 1142394.PSMK_20480 5e-127 461.8 Planctomycetes mutL GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 2IXI2@203682,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex MAG.T2.48_00604 1280380.KR100_07340 1.9e-19 103.2 Synechococcus apaH 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 1GAN7@1117,1GYK4@1129,COG0639@1,COG0639@2 NA|NA|NA T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases MAG.T2.48_00607 1385935.N836_04075 6.7e-110 404.8 Oscillatoriales nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 1G1DF@1117,1H8EP@1150,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source MAG.T2.48_00608 1142394.PSMK_27400 4.3e-45 188.0 Planctomycetes Bacteria 2IY82@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.48_00609 644966.Tmar_1928 8.3e-176 623.6 Clostridiales incertae sedis pckA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560 Bacteria 1TPQV@1239,248JE@186801,3WCR6@538999,COG1866@1,COG1866@2 NA|NA|NA F Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA MAG.T2.48_00611 497964.CfE428DRAFT_4519 9.6e-44 184.1 Verrucomicrobia yafV 3.5.1.3 ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 46T1B@74201,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase MAG.T2.48_00613 1206101.AZXC01000005_gene2844 4.2e-54 219.2 Actinobacteria Bacteria 2I6N2@201174,COG4188@1,COG4188@2 NA|NA|NA S Chlorophyllase enzyme MAG.T2.48_00614 243090.RB12774 4.9e-07 61.2 Planctomycetes gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXGK@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.48_00616 1142394.PSMK_19550 4e-116 425.2 Planctomycetes hflX ko:K03665 ko00000,ko03009 Bacteria 2IXH5@203682,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis MAG.T2.48_00617 1123242.JH636434_gene3522 1.3e-67 263.8 Planctomycetes tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2IXJP@203682,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction MAG.T2.48_00620 1123242.JH636437_gene6139 1.6e-32 146.0 Planctomycetes Bacteria 2IZSY@203682,COG1186@1,COG1186@2 NA|NA|NA J chain release factor MAG.T2.48_00621 661478.OP10G_3431 3.1e-90 339.0 Bacteria hipO GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009109,GO:0009111,GO:0009397,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019213,GO:0019439,GO:0019752,GO:0019877,GO:0034641,GO:0042219,GO:0042365,GO:0042558,GO:0042560,GO:0042737,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046451,GO:0046483,GO:0046655,GO:0046657,GO:0046700,GO:0046982,GO:0046983,GO:0050118,GO:0051186,GO:0051187,GO:0071704,GO:0071713,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 3.5.1.32,3.5.1.47,3.5.1.6,3.5.1.87 ko:K01436,ko:K01451,ko:K05823,ko:K06016,ko:K06048,ko:K12940,ko:K12941,ko:K21613 ko00240,ko00300,ko00360,ko01100,ko01110,ko01230,map00240,map00300,map00360,map01100,map01110,map01230 M00046,M00525 R00905,R01424,R02733,R04666 RC00064,RC00096,RC00162,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria COG1473@1,COG1473@2 NA|NA|NA S N-acetyldiaminopimelate deacetylase activity MAG.T2.48_00622 1123255.JHYS01000016_gene1091 2e-21 111.3 Comamonadaceae 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R14N@1224,2WHZ9@28216,4AIB3@80864,COG2340@1,COG2340@2,COG3055@1,COG3055@2,COG4447@1,COG4447@2 NA|NA|NA S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.48_00623 1123255.JHYS01000016_gene1091 9.1e-19 102.1 Comamonadaceae 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R14N@1224,2WHZ9@28216,4AIB3@80864,COG2340@1,COG2340@2,COG3055@1,COG3055@2,COG4447@1,COG4447@2 NA|NA|NA S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.48_00624 1142394.PSMK_08460 1.3e-40 172.6 Planctomycetes rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ97@203682,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors MAG.T2.48_00625 1142394.PSMK_08470 1.7e-56 226.1 Planctomycetes rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IYQK@203682,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release MAG.T2.48_00626 1142394.PSMK_08480 2e-39 169.1 Planctomycetes rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0R0@203682,COG0244@1,COG0244@2 NA|NA|NA J ribosomal protein l10 MAG.T2.48_00627 1408473.JHXO01000006_gene1414 1.7e-24 119.0 Bacteroidia rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2FSJH@200643,4NQAQ@976,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation MAG.T2.48_00629 867903.ThesuDRAFT_01035 2.4e-12 79.3 Firmicutes luxR ko:K10913 ko02020,ko02024,ko05111,map02020,map02024,map05111 ko00000,ko00001,ko03000 Bacteria 1V4AJ@1239,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator MAG.T2.48_00630 1142394.PSMK_24450 0.0 1792.3 Planctomycetes rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXVZ@203682,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.48_00631 1142394.PSMK_24440 0.0 1809.7 Planctomycetes rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXGN@203682,COG0086@1,COG0086@2,COG2190@1,COG2190@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.48_00632 157072.XP_008866675.1 8.1e-15 86.7 Eukaryota Eukaryota 2CZGI@1,2SAAG@2759 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T2.48_00633 1142394.PSMK_02400 4.9e-22 111.3 Planctomycetes ko:K06940 ko00000 Bacteria 2J0KU@203682,COG0727@1,COG0727@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0153) MAG.T2.48_00635 886293.Sinac_5925 2.9e-96 359.4 Planctomycetes rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 2IWTE@203682,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 MAG.T2.48_00638 1142394.PSMK_23820 9.3e-219 766.5 Planctomycetes lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2IXI5@203682,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner MAG.T2.48_00640 518766.Rmar_2259 9e-43 180.6 Bacteroidetes Order II. Incertae sedis lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 Bacteria 1FJ4Z@1100069,4NE14@976,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate MAG.T2.48_00641 765911.Thivi_1113 1.4e-47 196.8 Chromatiales lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1QKYH@1224,1S0N9@1236,1WXE9@135613,COG1043@1,COG1043@2 NA|NA|NA I Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.48_00642 1142394.PSMK_23050 6.2e-32 144.8 Planctomycetes Bacteria 2IZQK@203682,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T2.48_00643 452637.Oter_3710 5.9e-176 624.4 Opitutae purF 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 3K7AM@414999,46UIJ@74201,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine MAG.T2.48_00644 1142394.PSMK_07330 3.9e-70 271.2 Planctomycetes rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IYUB@203682,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit MAG.T2.48_00647 1142394.PSMK_21400 3.5e-21 108.2 Planctomycetes metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2J0IV@203682,COG0073@1,COG0073@2 NA|NA|NA J Putative tRNA binding domain MAG.T2.48_00648 1142394.PSMK_10920 2.6e-276 958.4 Planctomycetes ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 2IWX2@203682,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) MAG.T2.48_00650 1142394.PSMK_21450 3.2e-49 202.6 Planctomycetes zupT ko:K07238,ko:K11021,ko:K16267 ko00000,ko02000,ko02042 2.A.5.4.11,2.A.5.5 Bacteria 2IZ3C@203682,COG0428@1,COG0428@2 NA|NA|NA P ZIP Zinc transporter MAG.T2.48_00652 1142394.PSMK_24490 1.6e-198 699.9 Planctomycetes mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 Bacteria 2IXGV@203682,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity MAG.T2.48_00653 1142394.PSMK_25140 3.4e-47 194.9 Planctomycetes Bacteria 2IZW1@203682,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T2.48_00654 111781.Lepto7376_0826 2.9e-12 80.1 Oscillatoriales Bacteria 1G4Y4@1117,1HC4S@1150,COG2304@1,COG2304@2 NA|NA|NA S SMART von Willebrand factor, type A MAG.T2.48_00655 1123354.AUDR01000017_gene89 1.9e-79 302.8 Hydrogenophilales obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1KRYN@119069,1MUGZ@1224,2VIM2@28216,COG0536@1,COG0536@2 NA|NA|NA S GTP1/OBG MAG.T2.48_00656 1142394.PSMK_11760 3.1e-22 110.9 Planctomycetes rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J04T@203682,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family MAG.T2.48_00658 886293.Sinac_7563 1.8e-26 127.1 Planctomycetes Bacteria 2J0RJ@203682,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.48_00659 1330700.JQNC01000003_gene1699 2.7e-59 236.5 Deinococcus-Thermus dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1WIHX@1297,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T2.48_00661 1142394.PSMK_22190 2.8e-80 305.8 Planctomycetes 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 2IZ4J@203682,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T2.48_00662 1549858.MC45_02410 2.6e-52 213.0 Sphingomonadales cpg2 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 1MUSU@1224,2K0AC@204457,2TRTW@28211,COG0624@1,COG0624@2 NA|NA|NA E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases MAG.T2.48_00663 886293.Sinac_3140 1.7e-80 306.2 Planctomycetes dapF 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYCH@203682,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan MAG.T2.48_00664 1142394.PSMK_18850 5.7e-32 145.6 Planctomycetes 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 2J0VM@203682,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T2.48_00666 935948.KE386494_gene211 1.3e-14 85.5 Thermoanaerobacterales yutI Bacteria 1VAAU@1239,24R29@186801,42GUA@68295,COG0694@1,COG0694@2 NA|NA|NA O PFAM nitrogen-fixing NifU domain protein MAG.T2.48_00668 237368.SCABRO_01473 7.2e-14 84.0 Planctomycetes mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 2J1IV@203682,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family MAG.T2.48_00669 1142394.PSMK_02460 8.7e-17 94.4 Planctomycetes Bacteria 2J4S0@203682,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain MAG.T2.48_00670 1142394.PSMK_30150 8e-72 277.7 Planctomycetes Bacteria 2IYMW@203682,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase MAG.T2.48_00673 756272.Plabr_0491 1e-10 73.9 Planctomycetes Bacteria 2EEJC@1,2J0KE@203682,338DC@2 NA|NA|NA MAG.T2.48_00674 530564.Psta_3983 6.4e-15 87.4 Planctomycetes Bacteria 2EE5D@1,2J11M@203682,337ZY@2 NA|NA|NA S Protein of unknown function (DUF2752) MAG.T2.48_00675 1128421.JAGA01000002_gene1079 2e-59 236.5 Bacteria pvdM 3.4.13.19 ko:K01273,ko:K01274 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria COG2355@1,COG2355@2 NA|NA|NA E Zn-dependent dipeptidase, microsomal dipeptidase MAG.T2.48_00677 1142394.PSMK_30020 1.3e-70 273.5 Bacteria soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 ko:K03496,ko:K09000 ko00000,ko02048,ko03036,ko04812 Bacteria COG1192@1,COG1192@2,COG3170@1,COG3170@2 NA|NA|NA NU translation initiation factor activity MAG.T2.48_00678 998088.B565_3208 3.9e-43 182.2 Gammaproteobacteria Bacteria 1P0WK@1224,1SU5D@1236,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T2.48_00679 1123253.AUBD01000012_gene983 1.9e-62 246.5 Xanthomonadales aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iIT341.HP0283,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 Bacteria 1MUBK@1224,1RN4I@1236,1X42C@135614,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) MAG.T2.48_00680 1121440.AUMA01000007_gene1083 1.7e-122 446.8 Desulfovibrionales Bacteria 1MWIM@1224,2M8FD@213115,2WJY9@28221,42P71@68525,COG0204@1,COG0204@2,COG3176@1,COG3176@2 NA|NA|NA I SMART Phospholipid glycerol acyltransferase MAG.T2.48_00683 886293.Sinac_0717 2.9e-13 83.6 Planctomycetes Bacteria 2IY61@203682,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T2.48_00685 1157490.EL26_23175 1.1e-75 290.8 Alicyclobacillaceae Bacteria 1TR5N@1239,278ZW@186823,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) MAG.T2.48_00687 1458427.BAWN01000013_gene920 3.3e-73 282.0 Betaproteobacteria ko:K07133 ko00000 Bacteria 1R3UA@1224,2VQ1T@28216,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T2.48_00689 1123242.JH636434_gene5626 1.2e-57 230.3 Bacteria Bacteria COG4886@1,COG4886@2,COG5426@1,COG5426@2 NA|NA|NA D von Willebrand factor, type A MAG.T2.48_00690 365046.Rta_36030 5.6e-56 223.8 Comamonadaceae ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 ko:K03829 ko00000,ko01000 Bacteria 1QUHE@1224,2VTMP@28216,4AJXX@80864,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T2.48_00692 478741.JAFS01000001_gene1654 1.8e-23 115.5 Bacteria Bacteria 2ECCV@1,336B4@2 NA|NA|NA MAG.T2.48_00693 1340493.JNIF01000003_gene2381 4.8e-21 107.5 Bacteria Bacteria COG1695@1,COG1695@2 NA|NA|NA K negative regulation of transcription, DNA-templated MAG.T2.48_00696 1267534.KB906757_gene717 2.7e-52 212.2 Bacteria Bacteria 2C2X7@1,31WBU@2 NA|NA|NA MAG.T2.48_00701 391625.PPSIR1_15465 1.1e-95 356.7 Myxococcales deoC 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 Bacteria 1N8AG@1224,2WNEY@28221,2YYRJ@29,42S16@68525,COG0274@1,COG0274@2 NA|NA|NA H Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate MAG.T2.48_00702 1121957.ATVL01000011_gene3792 5.6e-115 421.0 Cytophagia namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 47JFR@768503,4NF98@976,COG1902@1,COG1902@2 NA|NA|NA C NADH flavin oxidoreductase NADH oxidase MAG.T2.48_00703 882082.SaccyDRAFT_1305 1.8e-84 319.3 Pseudonocardiales ko:K09992 ko00000 Bacteria 2GJFY@201174,4E1CS@85010,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3828@1,COG3828@2 NA|NA|NA G glucose sorbosone MAG.T2.48_00704 706587.Desti_0542 1.5e-123 451.4 Syntrophobacterales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1MW8K@1224,2MQ7A@213462,2WKQW@28221,42NNC@68525,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.48_00705 1123242.JH636437_gene5990 1.8e-17 96.3 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.48_00706 1142394.PSMK_06200 4.3e-93 348.2 Planctomycetes lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2IXVE@203682,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives MAG.T2.48_00709 1128421.JAGA01000001_gene2150 4.9e-91 341.7 unclassified Bacteria Bacteria 2NNW3@2323,COG0612@1,COG0612@2 NA|NA|NA S Belongs to the peptidase M16 family MAG.T2.48_00710 1131553.JIBI01000006_gene1097 1.6e-32 147.5 Nitrosomonadales Bacteria 1MVRF@1224,2VN6Y@28216,3725H@32003,COG1639@1,COG1639@2,COG2199@1,COG3706@2 NA|NA|NA T TIGRFAM Diguanylate cyclase MAG.T2.48_00711 1142394.PSMK_01260 2e-27 129.8 Planctomycetes recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 ko:K03474,ko:K03584 ko00750,ko01100,ko03440,map00750,map01100,map03440 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IZU9@203682,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination MAG.T2.48_00712 545276.KB898725_gene571 1.1e-53 217.2 Chromatiales rrp-1 ko:K18444 ko02020,map02020 M00662 ko00000,ko00001,ko00002,ko02022 Bacteria 1R7HC@1224,1RMA9@1236,1WXA2@135613,COG2199@1,COG3706@2 NA|NA|NA T TIGRFAM Diguanylate cyclase MAG.T2.48_00713 756272.Plabr_3467 7e-09 67.0 Planctomycetes 2.7.13.3 ko:K07647 ko02020,map02020 M00455 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2J1FC@203682,COG2198@1,COG2198@2 NA|NA|NA T (Hpt) domain MAG.T2.48_00714 1142394.PSMK_29610 9.1e-72 277.3 Planctomycetes 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 2IWSW@203682,COG1234@1,COG1234@2 NA|NA|NA S of the beta-lactamase MAG.T2.48_00715 1142394.PSMK_00010 2.6e-101 375.9 Planctomycetes dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837,GO:2000112 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2IWXU@203682,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T2.48_00716 886293.Sinac_3123 2e-112 412.9 Planctomycetes ko:K03924 ko00000,ko01000 Bacteria 2IWZM@203682,COG0714@1,COG0714@2 NA|NA|NA S associated with various cellular activities MAG.T2.48_00717 1123242.JH636434_gene5537 1e-48 200.7 Planctomycetes Bacteria 2IWV6@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.48_00718 1142394.PSMK_28880 3.9e-35 156.8 Planctomycetes Bacteria 2IWTG@203682,COG2304@1,COG2304@2 NA|NA|NA S Aerotolerance regulator N-terminal MAG.T2.48_00719 1142394.PSMK_05350 1.4e-99 370.9 Planctomycetes Bacteria 2IXY5@203682,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor (vWF) type A domain MAG.T2.48_00720 575540.Isop_3540 1.2e-11 79.7 Planctomycetes Bacteria 2J548@203682,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T2.48_00721 530564.Psta_2910 2.1e-92 346.3 Planctomycetes 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IXQ8@203682,COG1657@1,COG1657@2 NA|NA|NA I Prenyltransferase and squalene oxidase repeat MAG.T2.48_00723 1142394.PSMK_02570 6.2e-27 129.8 Planctomycetes comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2IY17@203682,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S competence protein ComEC Rec2 MAG.T2.48_00724 1121861.KB899911_gene1332 4.5e-59 235.3 Rhodospirillales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPV@1224,2JQYM@204441,2TR8S@28211,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) MAG.T2.48_00727 479434.Sthe_1657 5.6e-57 228.4 Thermomicrobia nfo GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 27XEG@189775,2G5XZ@200795,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin MAG.T2.48_00728 247490.KSU1_B0556 6.9e-54 218.0 Planctomycetes gnnA ko:K09949 ko00000 iAF987.Gmet_2352 Bacteria 2IXAX@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T2.48_00730 1142394.PSMK_20130 1e-56 227.3 Planctomycetes purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IYT2@203682,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T2.48_00731 1142394.PSMK_07590 1.7e-233 816.2 Planctomycetes purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IXRT@203682,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T2.48_00732 1142394.PSMK_27240 1.9e-15 90.9 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.48_00734 1142394.PSMK_27240 1.2e-22 115.2 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.48_00735 1142394.PSMK_12320 3.9e-127 461.8 Planctomycetes radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2IYD6@203682,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function MAG.T2.48_00736 1142394.PSMK_22880 5.4e-88 331.6 Planctomycetes nuoH 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IXH1@203682,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone MAG.T2.48_00737 316274.Haur_2274 1.2e-71 276.6 Chloroflexia Bacteria 2G6JP@200795,3773X@32061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal MAG.T2.48_00738 671143.DAMO_0414 2.8e-203 715.7 unclassified Bacteria Bacteria 2NNNV@2323,COG0642@1,COG2205@2 NA|NA|NA T Osmosensitive K+ channel His kinase sensor domain MAG.T2.48_00739 640510.BC1001_1049 1.5e-34 152.9 Burkholderiaceae kdpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 Bacteria 1K3NK@119060,1RABG@1224,2VQ72@28216,COG2156@1,COG2156@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex MAG.T2.48_00740 1254432.SCE1572_09215 7.9e-262 909.8 Myxococcales kdpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iAF987.Gmet_2434,iECNA114_1301.ECNA114_0634,iECSF_1327.ECSF_0632 Bacteria 1MU7D@1224,2WJC0@28221,2YWXY@29,42NGX@68525,COG2216@1,COG2216@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system MAG.T2.48_00741 521674.Plim_1871 5.9e-199 700.7 Planctomycetes kdpA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717 Bacteria 2IY0R@203682,COG2060@1,COG2060@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane MAG.T2.48_00747 314278.NB231_13786 8.9e-28 131.0 Gammaproteobacteria Bacteria 1RGPY@1224,1SDVV@1236,2EBAQ@1,335BC@2 NA|NA|NA S Putative MetA-pathway of phenol degradation MAG.T2.48_00748 682795.AciX8_0042 5.3e-22 110.9 Acidobacteriia folK 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940,ko:K17488 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R10348,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC02504,RC03131,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0041 Bacteria 2JJMS@204432,3Y57F@57723,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MAG.T2.48_00749 1121360.AUAQ01000014_gene1349 6.4e-13 82.4 Corynebacteriaceae Bacteria 22PYI@1653,2DUX6@1,2HPKU@201174,33STZ@2 NA|NA|NA MAG.T2.48_00750 1142394.PSMK_11090 0.0 1487.6 Planctomycetes carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2IXR6@203682,COG0458@1,COG0458@2 NA|NA|NA F Carbamoylphosphate synthase large subunit MAG.T2.48_00753 1254432.SCE1572_27480 8.9e-16 90.5 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.48_00757 452637.Oter_3626 7.2e-66 258.1 Opitutae spoIVFB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K06212,ko:K06402 ko00000,ko01000,ko01002,ko02000 1.A.16.1.1,1.A.16.1.3 Bacteria 3K9SZ@414999,46SM2@74201,COG0517@1,COG0517@2,COG1994@1,COG1994@2 NA|NA|NA S Peptidase M50 MAG.T2.48_00758 1479237.JMLY01000001_gene3457 9e-16 90.1 Bacteria 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria COG0599@1,COG0599@2 NA|NA|NA S peroxiredoxin activity MAG.T2.48_00759 408672.NBCG_01378 1.2e-72 280.4 Propionibacteriales moaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 Bacteria 2GN0V@201174,4DP3D@85009,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate MAG.T2.48_00760 1121015.N789_02375 1.7e-51 209.5 Xanthomonadales ko:K07090 ko00000 Bacteria 1RD5A@1224,1S6M1@1236,1XAJC@135614,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T2.48_00761 1142394.PSMK_14830 4.5e-16 91.3 Planctomycetes moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 2IZSA@203682,COG0314@1,COG0314@2 NA|NA|NA H Molybdopterin converting factor, large subunit MAG.T2.48_00763 243090.RB295 1.7e-70 273.5 Planctomycetes moeA 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 2IXJ1@203682,COG0303@1,COG0303@2 NA|NA|NA H Molybdenum cofactor synthesis domain protein MAG.T2.48_00764 314285.KT71_16136 3.5e-37 161.8 unclassified Gammaproteobacteria moaC GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 1J7VU@118884,1RCYZ@1224,1S3ST@1236,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) MAG.T2.48_00765 1128421.JAGA01000002_gene1814 7.1e-35 154.1 Bacteria mog GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75,2.8.1.12,4.99.1.12 ko:K03635,ko:K03831,ko:K09121 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395,R09726 RC00002,RC02507 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1969,iECABU_c1320.ECABU_c00100,iECED1_1282.ECED1_0009,iECNA114_1301.ECNA114_4653,iECP_1309.ECP_0010,iECS88_1305.ECS88_0010,iECSF_1327.ECSF_0009,iECUMN_1333.ECUMN_0010,iEcSMS35_1347.EcSMS35_0008,iLF82_1304.LF82_1379,iNRG857_1313.NRG857_00050,iUMN146_1321.UM146_22820 Bacteria COG0521@1,COG0521@2 NA|NA|NA H Mo-molybdopterin cofactor metabolic process MAG.T2.48_00766 1121406.JAEX01000005_gene2885 8.9e-09 67.4 Desulfovibrionales mobA 2.7.7.77,4.6.1.17 ko:K03637,ko:K03752,ko:K13818 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372,R11581 RC03425 ko00000,ko00001,ko01000 Bacteria 1RKCH@1224,2MC7V@213115,2WPF6@28221,42T8X@68525,COG0746@1,COG0746@2 NA|NA|NA H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor MAG.T2.48_00767 530564.Psta_2472 6.8e-14 84.7 Planctomycetes cmk 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2J10J@203682,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T2.48_00768 1210884.HG799463_gene9464 2.9e-133 482.6 Planctomycetes ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2IX59@203682,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T2.48_00769 1142394.PSMK_07370 3.3e-27 129.0 Planctomycetes ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IZ2E@203682,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB MAG.T2.48_00770 1134474.O59_001116 7.2e-08 65.1 Gammaproteobacteria Bacteria 1RGM6@1224,1S5SV@1236,COG3291@1,COG3291@2 NA|NA|NA M TIGRFAM conserved repeat domain MAG.T2.48_00771 479435.Kfla_1584 2.3e-92 345.9 Propionibacteriales manC 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRM@201174,4DPTJ@85009,COG0836@1,COG0836@2 NA|NA|NA M Nucleotidyl transferase MAG.T2.48_00774 1380387.JADM01000003_gene2662 6.6e-60 237.7 Oceanospirillales ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MWC9@1224,1T1GE@1236,1XIAQ@135619,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family MAG.T2.48_00775 243090.RB9128 1.7e-36 159.1 Bacteria Bacteria 29CWT@1,2ZZUX@2 NA|NA|NA S UPF0314 protein MAG.T2.48_00777 1142394.PSMK_08180 5.7e-28 130.6 Planctomycetes yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2J0EV@203682,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA MAG.T2.48_00778 1142394.PSMK_24880 4.3e-54 218.4 Planctomycetes pgl 3.1.1.31,3.5.99.6,5.3.1.9 ko:K01057,ko:K01810,ko:K02564 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00006,M00008,M00114 R00765,R02035,R02739,R02740,R03321 RC00163,RC00376,RC00537,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2J0I5@203682,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MAG.T2.48_00782 530564.Psta_1118 2.9e-48 199.1 Planctomycetes Bacteria 2J0K4@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family MAG.T2.48_00784 1123242.JH636435_gene1662 1.1e-24 122.5 Planctomycetes Bacteria 2BWJE@1,2IYWZ@203682,2ZDHQ@2 NA|NA|NA MAG.T2.48_00785 530564.Psta_1115 1.1e-38 168.7 Planctomycetes Bacteria 2ETUV@1,2J2Q3@203682,33MC3@2 NA|NA|NA MAG.T2.48_00786 344747.PM8797T_02374 1.7e-84 320.1 Planctomycetes Bacteria 2IY1Z@203682,COG1100@1,COG1100@2 NA|NA|NA S Small GTP-binding protein MAG.T2.48_00787 886293.Sinac_6239 2.5e-23 116.3 Planctomycetes vWFA2 ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2J0MU@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain MAG.T2.48_00788 1298858.AUEL01000017_gene2814 1.8e-149 535.8 Phyllobacteriaceae ko:K07133 ko00000 Bacteria 1MWBT@1224,2U050@28211,43I4B@69277,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T2.48_00789 323098.Nwi_2109 5.3e-07 60.1 Bradyrhizobiaceae Bacteria 1MV69@1224,2TT3J@28211,3JV7K@41294,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family N-terminal MAG.T2.48_00790 1268622.AVS7_02044 3.5e-35 154.8 Comamonadaceae ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1RCQ1@1224,2VXHM@28216,4AHK7@80864,COG1487@1,COG1487@2 NA|NA|NA S Domain of unknown function (DUF4411) MAG.T2.48_00791 324602.Caur_1811 3.8e-109 401.7 Chloroflexi Bacteria 2G6ZX@200795,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain MAG.T2.48_00792 1042209.HK44_008860 6e-80 304.3 Gammaproteobacteria Bacteria 1MY3Y@1224,1S00U@1236,COG5340@1,COG5340@2 NA|NA|NA K Transcriptional regulator, AbiEi antitoxin N-terminal domain MAG.T2.48_00793 1396141.BATP01000003_gene4933 7.2e-149 533.9 Verrucomicrobiae xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038 Bacteria 2ITJ2@203494,46TT2@74201,COG2115@1,COG2115@2 NA|NA|NA G PFAM Xylose isomerase domain protein TIM barrel MAG.T2.48_00795 886293.Sinac_4712 9.4e-31 140.6 Planctomycetes Bacteria 2J1I0@203682,COG2353@1,COG2353@2 NA|NA|NA S YceI-like domain MAG.T2.48_00797 521674.Plim_1693 7.6e-60 239.2 Planctomycetes fliD GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IXUU@203682,COG1345@1,COG1345@2 NA|NA|NA N flagellar hook-associated protein 2 MAG.T2.48_00798 1125863.JAFN01000001_gene2682 5.2e-49 201.8 Deltaproteobacteria parB ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1MW2E@1224,2WNG8@28221,42M8S@68525,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family MAG.T2.48_00801 1121013.P873_09895 2.3e-74 286.6 Xanthomonadales ko:K07576 ko00000 Bacteria 1MUDD@1224,1RPZC@1236,1X523@135614,COG1236@1,COG1236@2 NA|NA|NA J exonuclease of the beta-lactamase fold involved in RNA processing MAG.T2.48_00802 243090.RB6221 7.7e-185 654.4 Planctomycetes Bacteria 2IXDX@203682,COG5549@1,COG5549@2 NA|NA|NA O Domain of unknown function (DUF5117) MAG.T2.48_00803 449447.MAE_41760 2e-11 78.2 Bacteria Bacteria COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T2.48_00804 1123277.KB893172_gene856 3e-71 275.0 Cytophagia 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47M10@768503,4NG0V@976,COG3622@1,COG3622@2 NA|NA|NA G Belongs to the hyi family MAG.T2.48_00805 32507.XP_006802795.1 1.3e-47 198.4 Actinopterygii TGM1 GO:0001533,GO:0002376,GO:0003674,GO:0003810,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0005912,GO:0005913,GO:0006464,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007275,GO:0007599,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008544,GO:0009611,GO:0009653,GO:0009887,GO:0009888,GO:0009913,GO:0009987,GO:0010837,GO:0010838,GO:0012501,GO:0016020,GO:0016043,GO:0016740,GO:0016746,GO:0016755,GO:0018149,GO:0019538,GO:0030054,GO:0030154,GO:0030216,GO:0030855,GO:0031224,GO:0031424,GO:0032501,GO:0032502,GO:0036211,GO:0042060,GO:0042127,GO:0042381,GO:0043163,GO:0043170,GO:0043412,GO:0043588,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045087,GO:0045229,GO:0045787,GO:0048513,GO:0048518,GO:0048522,GO:0048731,GO:0048856,GO:0048869,GO:0050678,GO:0050679,GO:0050789,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051726,GO:0060429,GO:0065007,GO:0065008,GO:0070161,GO:0070268,GO:0071704,GO:0071840,GO:0071944,GO:0140096,GO:1901564 2.3.2.13 ko:K05619 ko00000,ko01000 Metazoa 2CD5G@1,2QQ46@2759,38DTB@33154,3B9AA@33208,3CRPR@33213,487Q2@7711,48W82@7742,49ZZ1@7898 NA|NA|NA S Transglutaminase 1 like 1 MAG.T2.48_00808 497965.Cyan7822_0583 4.3e-22 114.8 Cyanothece 3.2.1.22,3.4.24.40 ko:K01406,ko:K07407,ko:K21449 ko00052,ko00561,ko00600,ko00603,ko01503,map00052,map00561,map00600,map00603,map01503 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 Bacteria 1GC1J@1117,3KJVM@43988,COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG5492@1,COG5492@2 NA|NA|NA QU Polymorphic membrane protein Chlamydia MAG.T2.48_00809 1288494.EBAPG3_9640 4e-92 345.5 Nitrosomonadales MA20_16020 2.6.1.11,2.6.1.13,2.6.1.17,2.6.1.82 ko:K00819,ko:K00821,ko:K09251 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R01155,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1R6U9@1224,2VR1P@28216,371Z3@32003,COG4992@1,COG4992@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T2.48_00810 706436.HMPREF9074_08813 6.3e-30 138.7 Capnocytophaga ko:K09928 ko00000 Bacteria 1EQQ4@1016,1HY3M@117743,4NETR@976,COG1216@1,COG1216@2,COG3216@1,COG3216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein MAG.T2.48_00811 1142394.PSMK_01920 2.2e-39 170.2 Bacteria 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase MAG.T2.48_00812 1142394.PSMK_30160 4e-73 282.3 Planctomycetes ko:K16033 ko01051,ko01052,ko01130,map01051,map01052,map01130 R09851 RC01363 ko00000,ko00001 Bacteria 2IX1U@203682,COG0644@1,COG0644@2 NA|NA|NA C COG0644 Dehydrogenases (flavoproteins) MAG.T2.48_00813 983917.RGE_38580 1.9e-24 120.2 unclassified Burkholderiales rapK GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 ko:K18239,ko:K18240 ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110 M00117 R01302,R10583,R10597 RC00350,RC00491,RC02148,RC03212 ko00000,ko00001,ko00002,ko01000 Bacteria 1KKUK@119065,1NQGP@1224,2VMPK@28216,COG0251@1,COG0251@2 NA|NA|NA J pteridine-dependent deoxygenase MAG.T2.48_00814 1142394.PSMK_30840 1.5e-66 261.2 Planctomycetes cfa3 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2J1Z9@203682,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T2.48_00815 1142394.PSMK_30870 3e-20 105.1 Bacteria fabZ 3.5.1.108,4.2.1.59 ko:K02078,ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria COG0236@1,COG0236@2,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity MAG.T2.48_00817 1142394.PSMK_30850 1.2e-29 138.3 Bacteria htrB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 ko:K02517,ko:K20543,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 1.B.55.3 Bacteria COG1560@1,COG1560@2 NA|NA|NA M Kdo2-lipid A biosynthetic process MAG.T2.48_00818 235985.BBPN01000034_gene851 8.4e-34 151.0 Streptacidiphilus 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 2GN6G@201174,2NIDV@228398,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase MAG.T2.48_00819 102129.Lepto7375DRAFT_3866 3.1e-21 109.0 Cyanobacteria Bacteria 1G9JP@1117,COG0500@1,COG2226@2 NA|NA|NA Q SAM (And some other nucleotide) binding motif MAG.T2.48_00820 1121272.KB903255_gene5739 2.3e-39 170.2 Micromonosporales ko:K03933 ko00000 AA10,CBM73 Bacteria 2GP7X@201174,4D8M1@85008,COG3397@1,COG3397@2 NA|NA|NA G Lytic polysaccharide mono-oxygenase, cellulose-degrading MAG.T2.48_00821 530564.Psta_4579 2.4e-44 186.8 Planctomycetes Bacteria 2IXDR@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.48_00822 595460.RRSWK_01304 0.0 1206.4 Planctomycetes gcvP GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3318 Bacteria 2IYB9@203682,COG0403@1,COG0403@2,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MAG.T2.48_00823 204669.Acid345_3483 1.7e-67 264.2 Acidobacteriia Bacteria 2JICT@204432,3Y46R@57723,COG0265@1,COG0265@2,COG2234@1,COG2234@2 NA|NA|NA O PA domain MAG.T2.48_00824 1297742.A176_06560 2.3e-108 399.1 Myxococcales 1.1.1.91 ko:K05882 ko00000,ko01000 Bacteria 1MV2Y@1224,2X27R@28221,2YXCB@29,43475@68525,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T2.48_00825 1142394.PSMK_21330 6.9e-25 120.6 Planctomycetes nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2J09T@203682,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_00826 1499502.EV12_0944 2.3e-12 78.2 Cyanobacteria Bacteria 1GF7Z@1117,1MNUQ@1212,2DYAZ@1,348ZI@2 NA|NA|NA MAG.T2.48_00828 1280954.HPO_15768 1.4e-47 196.4 Bacteria pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter MAG.T2.48_00829 1123508.JH636441_gene3745 4.6e-84 318.2 Bacteria nadR Bacteria COG3172@1,COG3172@2 NA|NA|NA H ATPase kinase involved in NAD metabolism MAG.T2.48_00831 391603.FBALC1_06068 1.1e-18 100.9 Flavobacteriia Bacteria 1IAX5@117743,2ESNM@1,33K76@2,4NYEG@976 NA|NA|NA MAG.T2.48_00832 243090.RB11252 3.3e-158 565.1 Bacteria Bacteria COG2124@1,COG2124@2 NA|NA|NA Q cytochrome p450 MAG.T2.48_00833 1449049.JONW01000011_gene2311 1.5e-21 110.5 Caulobacterales Bacteria 1N9U6@1224,2E902@1,2KH8D@204458,2UFG4@28211,3339H@2 NA|NA|NA MAG.T2.48_00834 240016.ABIZ01000001_gene760 1.7e-30 140.2 Bacteria Bacteria COG0589@1,COG0589@2 NA|NA|NA T AMP binding MAG.T2.48_00835 671143.DAMO_0863 1.2e-06 60.1 Bacteria Bacteria COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family MAG.T2.48_00836 1396141.BATP01000060_gene4560 3.5e-128 466.5 Verrucomicrobiae Bacteria 2IV44@203494,46UAE@74201,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_00837 261292.Nit79A3_0074 5.1e-123 447.6 Nitrosomonadales MA20_02030 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 1MW32@1224,2VIQ7@28216,3731Y@32003,COG0451@1,COG0451@2 NA|NA|NA M NAD(P)H-binding MAG.T2.48_00838 261292.Nit79A3_0073 7e-112 410.6 Nitrosomonadales panE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0036094,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15110 Bacteria 1PMYH@1224,2W06Z@28216,3740N@32003,COG1893@1,COG1893@2 NA|NA|NA H PFAM Ketopantoate reductase ApbA PanE, C-terminal MAG.T2.48_00839 1121015.N789_10900 4.7e-30 138.7 Xanthomonadales Bacteria 1QT8E@1224,1T7Y2@1236,1X9WU@135614,2B2RF@1,31VBJ@2 NA|NA|NA MAG.T2.48_00840 1121015.N789_10895 7.9e-28 131.0 Xanthomonadales ko:K10947 ko00000,ko03000 Bacteria 1N3KH@1224,1SAGS@1236,1XAJV@135614,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T2.48_00841 756272.Plabr_1631 5.7e-33 147.9 Bacteria Bacteria COG0569@1,COG0569@2 NA|NA|NA P domain protein MAG.T2.48_00842 570952.ATVH01000015_gene1382 8.9e-28 130.6 Rhodospirillales ko:K07481 ko00000 Bacteria 1MVDK@1224,2JQR2@204441,2TS7B@28211,COG3039@1,COG3039@2 NA|NA|NA L Transposase MAG.T2.48_00849 1380391.JIAS01000014_gene2157 1.6e-90 339.0 Rhodospirillales lsfA 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1MX2B@1224,2JRD7@204441,2TT09@28211,COG0450@1,COG0450@2 NA|NA|NA O C-terminal domain of 1-Cys peroxiredoxin MAG.T2.48_00850 378806.STAUR_3800 1.8e-49 202.2 Myxococcales Bacteria 1RH8Z@1224,2X3CB@28221,2YVDI@29,43825@68525,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase MAG.T2.48_00851 1384056.N787_13325 9.2e-10 69.7 Proteobacteria hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1N8CQ@1224,COG1544@1,COG1544@2 NA|NA|NA J Sigma 54 modulation protein / S30EA ribosomal protein MAG.T2.48_00852 1304885.AUEY01000019_gene1163 2.1e-78 299.7 Deltaproteobacteria terC ko:K05794 ko00000 Bacteria 1MUNR@1224,2WJI0@28221,42PJP@68525,COG0861@1,COG0861@2 NA|NA|NA P membrane protein, TerC MAG.T2.48_00853 1313421.JHBV01000030_gene2052 1.8e-31 143.3 Bacteroidetes ko:K08714 ko00000,ko02000 1.A.1.14 Bacteria 2Z7ZD@2,4NYV9@976,COG1226@1 NA|NA|NA P Ion transport protein MAG.T2.48_00854 1123257.AUFV01000015_gene3552 1.6e-149 536.6 Xanthomonadales pykF4 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1NNNX@1224,1RYF5@1236,1X9M9@135614,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase, barrel domain MAG.T2.48_00855 452637.Oter_1867 1.2e-105 390.2 Opitutae ko:K18101 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003 GT1 Bacteria 3K9Z5@414999,46THE@74201,COG1819@1,COG1819@2 NA|NA|NA H glycosyl transferase family 28 MAG.T2.48_00856 278957.ABEA03000085_gene2615 4.4e-141 507.7 Opitutae 1.1.1.1 ko:K13953,ko:K13979 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 3K791@414999,46WDP@74201,COG1064@1,COG1064@2 NA|NA|NA S alcohol dehydrogenase MAG.T2.48_00857 1122611.KB903996_gene7548 1.8e-15 88.2 Streptosporangiales ko:K07729 ko00000,ko03000 Bacteria 2GQIU@201174,4EK4N@85012,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain MAG.T2.48_00858 1161401.ASJA01000012_gene786 2.6e-12 78.6 Proteobacteria Bacteria 1NM7U@1224,2FFPQ@1,33DCS@2 NA|NA|NA MAG.T2.48_00859 926550.CLDAP_19500 7.4e-28 132.1 Bacteria 3.1.4.46 ko:K01126,ko:K21449 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000,ko02000 1.B.40.2 Bacteria COG0584@1,COG0584@2,COG0823@1,COG0823@2,COG3210@1,COG3210@2,COG4886@1,COG4886@2 NA|NA|NA S regulation of response to stimulus MAG.T2.48_00860 70448.A0A090M4S4 2.7e-15 89.7 Chlorophyta Viridiplantae 2CYB0@1,2S3AJ@2759,34I74@3041,37VHI@33090 NA|NA|NA S Aspartyl protease MAG.T2.48_00861 595460.RRSWK_07136 3.1e-148 531.9 Planctomycetes Bacteria 2IYQV@203682,COG0702@1,COG0702@2 NA|NA|NA GM PFAM NAD-dependent epimerase dehydratase MAG.T2.48_00862 631454.N177_2854 9.2e-88 330.9 Rhodobiaceae tlyC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 1JND1@119043,1MV3P@1224,2TS80@28211,COG1253@1,COG1253@2 NA|NA|NA S Domain of unknown function DUF21 MAG.T2.48_00867 1229172.JQFA01000005_gene54 8.2e-11 75.1 Oscillatoriales Bacteria 1G208@1117,1HAM3@1150,COG2319@1,COG2319@2 NA|NA|NA S Wd-40 repeat MAG.T2.48_00869 1205680.CAKO01000029_gene5240 2.9e-36 157.9 Alphaproteobacteria ybaA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1RHC1@1224,2UC7A@28211,COG5507@1,COG5507@2 NA|NA|NA S RNA signal recognition particle 4.5S RNA MAG.T2.48_00870 62928.azo2405 5.5e-56 224.2 Rhodocyclales ohr ko:K04063 ko00000 Bacteria 1RD1A@1224,2KXA8@206389,2VR4T@28216,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein MAG.T2.48_00871 251221.35210693 1.4e-28 132.5 Cyanobacteria ko:K06996 ko00000 Bacteria 1G8CB@1117,COG3324@1,COG3324@2 NA|NA|NA S Glyoxalase-like domain MAG.T2.48_00872 1123073.KB899241_gene3513 6.8e-44 183.7 Xanthomonadales dps GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0006950,GO:0008150,GO:0008199,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 ko:K04047 ko00000,ko03036 Bacteria 1RAC5@1224,1RR4N@1236,1X85K@135614,COG0783@1,COG0783@2 NA|NA|NA P Ferritin-like domain MAG.T2.48_00873 886293.Sinac_0491 8.3e-62 244.6 Planctomycetes Bacteria 2IZDA@203682,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase class C MAG.T2.48_00876 1141106.CAIB01000281_gene2622 1.5e-07 62.4 Staphylococcaceae Bacteria 1VGSH@1239,4GZHJ@90964,4HQ68@91061,COG3877@1,COG3877@2 NA|NA|NA S Protein of unknown function (DUF2089) MAG.T2.48_00878 1120983.KB894570_gene1908 7.2e-08 62.4 Rhodobiaceae Bacteria 1JPK7@119043,1N74T@1224,2E4YG@1,2UGKQ@28211,32ZSB@2 NA|NA|NA S Protein of unknown function (DUF3309) MAG.T2.48_00880 864069.MicloDRAFT_00024650 9.9e-34 151.8 Alphaproteobacteria Bacteria 1NTTH@1224,2UQ4Q@28211,COG3852@1,COG3852@2 NA|NA|NA T Histidine kinase MAG.T2.48_00881 521674.Plim_2876 1.3e-26 127.1 Planctomycetes ko:K02282 ko00000,ko02035,ko02044 Bacteria 2J0EY@203682,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T2.48_00882 1122176.KB903609_gene5148 3.6e-71 276.6 Bacteroidetes Bacteria 4NI4U@976,COG5337@1,COG5337@2 NA|NA|NA M COG5337 Spore coat assembly protein MAG.T2.48_00883 227086.JGI_V11_92794 2.9e-108 398.7 Eukaryota 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Eukaryota COG0136@1,KOG4777@2759 NA|NA|NA E aspartate-semialdehyde dehydrogenase activity MAG.T2.48_00884 1144275.COCOR_01546 5.8e-29 134.0 Myxococcales apaG ko:K06195 ko00000 Bacteria 1MZ2Z@1224,2WWZ0@28221,2YVD5@29,431ED@68525,COG2967@1,COG2967@2 NA|NA|NA P ApaG domain MAG.T2.48_00885 1142394.PSMK_15840 2.9e-76 292.0 Planctomycetes trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2494,iJN746.PP_0422 Bacteria 2IX3M@203682,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family MAG.T2.48_00886 1142394.PSMK_17410 7.6e-12 78.2 Planctomycetes ko:K07052,ko:K09696 ko02010,ko02020,map02010,map02020 M00253 ko00000,ko00001,ko00002,ko02000 3.A.1.115 Bacteria 2J1C8@203682,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T2.48_00887 1254432.SCE1572_37315 2.6e-125 455.3 Myxococcales trpS 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV4T@1224,2WJI2@28221,2YV60@29,42MCV@68525,COG0180@1,COG0180@2 NA|NA|NA J tRNA synthetases class I (W and Y) MAG.T2.48_00888 1142394.PSMK_26590 8.6e-19 101.3 Planctomycetes flgH GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 ko:K02393 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IZXJ@203682,COG2063@1,COG2063@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation MAG.T2.48_00889 744980.TRICHSKD4_4363 2.1e-07 63.9 Alphaproteobacteria flgA ko:K02279,ko:K02386 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Bacteria 1PM4C@1224,2TRUS@28211,COG1261@1,COG1261@2 NA|NA|NA N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly MAG.T2.48_00890 1142394.PSMK_26610 1.8e-65 256.1 Planctomycetes flgG ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IXW0@203682,COG4786@1,COG4786@2 NA|NA|NA N Flagellar basal body rod protein MAG.T2.48_00891 1142394.PSMK_26630 2.9e-28 132.5 Planctomycetes flhO GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02388,ko:K02391,ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IZZQ@203682,COG4786@1,COG4786@2 NA|NA|NA N basal body rod protein MAG.T2.48_00893 1142394.PSMK_10300 1.9e-64 253.1 Planctomycetes xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2IY3V@203682,COG4974@1,COG4974@2 NA|NA|NA D tyrosine recombinase XerC MAG.T2.48_00894 1337936.IJ00_26875 5.9e-08 65.1 Nostocales lgt ko:K08930,ko:K18546 ko02020,map02020 ko00000,ko00001,ko00194,ko01000,ko01002 Bacteria 1G557@1117,1HQD0@1161,COG3064@1,COG3064@2 NA|NA|NA M TIGRFAM PEP-CTERM protein sorting domain MAG.T2.48_00895 1142394.PSMK_24920 2e-126 459.5 Planctomycetes zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IXCV@203682,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone MAG.T2.48_00896 661478.OP10G_2391 1.9e-132 479.9 Bacteria 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria COG1409@1,COG1409@2,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase MAG.T2.48_00900 1048339.KB913029_gene1974 5.3e-195 687.2 Frankiales asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iSDY_1059.SDY_2327 Bacteria 2HFYJ@201174,4EWHK@85013,COG0017@1,COG0017@2 NA|NA|NA J tRNA synthetases class II (D, K and N) MAG.T2.48_00902 118005.AWNK01000003_gene2338 1.9e-25 121.7 Bacteria groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T2.48_00903 1142394.PSMK_31900 1.6e-227 795.4 Planctomycetes groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2IXA7@203682,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T2.48_00904 521674.Plim_2840 1.8e-07 63.9 Planctomycetes Bacteria 2IZIS@203682,COG4968@1,COG4968@2 NA|NA|NA NU Protein of unknown function (DUF1559) MAG.T2.48_00905 497964.CfE428DRAFT_4941 1.1e-13 82.8 Verrucomicrobia Bacteria 2E5PI@1,330E7@2,46W49@74201 NA|NA|NA MAG.T2.48_00906 649638.Trad_1873 4.9e-98 364.8 Deinococcus-Thermus aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1WKYW@1297,COG0337@1,COG0337@2 NA|NA|NA E 3-dehydroquinate synthase MAG.T2.48_00907 756272.Plabr_3719 2.5e-77 296.2 Planctomycetes 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IY5I@203682,COG0265@1,COG0265@2,COG0793@1,COG0793@2 NA|NA|NA O PDZ domain (Also known as DHR MAG.T2.48_00908 1210046.B277_12831 4.2e-93 349.0 Intrasporangiaceae 3.1.3.1,3.1.3.5,3.6.1.45 ko:K01077,ko:K11751 ko00230,ko00240,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00730,map00760,map00790,map01100,map01110,map02020 M00126 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2GP11@201174,4FIMX@85021,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity MAG.T2.48_00909 1123277.KB893172_gene887 1.1e-25 124.0 Cytophagia ko:K09992 ko00000 Bacteria 47JTV@768503,4NFYI@976,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3241@1,COG3241@2,COG3828@1,COG3828@2 NA|NA|NA CG PFAM Blue (type 1) copper domain MAG.T2.48_00910 1121447.JONL01000002_gene2262 5.7e-96 357.8 Desulfovibrionales Bacteria 1MWE5@1224,2MGAZ@213115,2WIYP@28221,42MCE@68525,COG0463@1,COG0463@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.48_00911 1125863.JAFN01000001_gene533 5.4e-35 154.8 Deltaproteobacteria waaE ko:K12984 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 Bacteria 1QU2Q@1224,2X6Y1@28221,43BK5@68525,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 MAG.T2.48_00912 945713.IALB_1953 2.2e-23 116.3 Bacteria Bacteria COG2353@1,COG2353@2 NA|NA|NA O YceI-like domain MAG.T2.48_00915 1089545.KB913037_gene1834 6.5e-59 235.3 Pseudonocardiales mhpA 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK88@201174,4E342@85010,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T2.48_00916 264732.Moth_1280 2e-37 162.9 Thermoanaerobacterales menG 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQEA@1239,2495M@186801,42FAN@68295,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) MAG.T2.48_00917 362242.MUL_0911 6.2e-112 411.4 Mycobacteriaceae Bacteria 234KQ@1762,2GIUM@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily MAG.T2.48_00918 756272.Plabr_2647 1.3e-29 137.9 Planctomycetes 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IXRK@203682,COG3850@1,COG3850@2,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T2.48_00919 1121456.ATVA01000011_gene1356 2.3e-12 79.3 Proteobacteria 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 1QVAR@1224,COG2204@1,COG2204@2 NA|NA|NA T PFAM Response regulator receiver domain MAG.T2.48_00920 1288963.ADIS_1340 3.4e-111 408.7 Cytophagia Bacteria 47KU9@768503,4NFR2@976,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 MAG.T2.48_00922 926560.KE387027_gene656 4.8e-40 171.4 Deinococcus-Thermus kynB GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1WJZU@1297,COG1878@1,COG1878@2 NA|NA|NA S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation MAG.T2.48_00923 263358.VAB18032_28766 4.5e-112 411.8 Micromonosporales kmo GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNR6@201174,4D9IQ@85008,COG0654@1,COG0654@2 NA|NA|NA CH Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid MAG.T2.48_00924 58123.JOFJ01000017_gene4197 3.8e-134 485.0 Streptosporangiales kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJQ@201174,4EH57@85012,COG3844@1,COG3844@2 NA|NA|NA E Aminotransferase class-V MAG.T2.48_00925 5786.XP_003292085.1 2.2e-114 419.1 Amoebozoa ACMSD GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 Eukaryota 3XBM6@554915,COG2159@1,KOG4245@2759 NA|NA|NA S Amidohydrolase MAG.T2.48_00926 596153.Alide_1406 1.5e-30 141.4 Comamonadaceae arnT 2.4.2.43 ko:K07264 ko01503,map01503 M00721 R09773,R09774,R09781 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Bacteria 1NMIZ@1224,2VMHK@28216,4ACZ5@80864,COG1807@1,COG1807@2 NA|NA|NA M PFAM glycosyl transferase family 39 MAG.T2.48_00927 1380391.JIAS01000016_gene430 4.4e-119 435.3 Rhodospirillales rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MU49@1224,2JQDT@204441,2TR6Q@28211,COG0513@1,COG0513@2 NA|NA|NA JKL Belongs to the DEAD box helicase family MAG.T2.48_00928 1144275.COCOR_00869 8.1e-47 193.7 Proteobacteria nbaC 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 Bacteria 1R4UW@1224,COG0662@1,COG0662@2 NA|NA|NA G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate MAG.T2.48_00930 1123242.JH636435_gene1401 4.5e-20 104.0 Planctomycetes Bacteria 2EGJW@1,2J4FU@203682,33AC1@2 NA|NA|NA MAG.T2.48_00936 1267533.KB906733_gene3472 1.2e-21 112.1 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_00937 344747.PM8797T_23701 2.3e-236 825.1 Planctomycetes 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY9E@203682,COG1070@1,COG1070@2 NA|NA|NA G MutL protein MAG.T2.48_00938 1123242.JH636435_gene2228 2e-107 396.0 Planctomycetes Bacteria 28II6@1,2IXG8@203682,2Z8JB@2 NA|NA|NA MAG.T2.48_00939 756272.Plabr_3381 6.7e-86 324.7 Planctomycetes Bacteria 28MEN@1,2IZ1H@203682,2ZASA@2 NA|NA|NA MAG.T2.48_00940 344747.PM8797T_23686 3e-61 241.9 Planctomycetes Bacteria 29ZH8@1,2J0G3@203682,30MGZ@2 NA|NA|NA MAG.T2.48_00941 756272.Plabr_3383 3.2e-76 292.0 Planctomycetes Bacteria 28MYQ@1,2IZUC@203682,2ZB5K@2 NA|NA|NA MAG.T2.48_00942 756272.Plabr_3384 1e-58 234.2 Planctomycetes Bacteria 2ANS9@1,2IZX5@203682,31DS7@2 NA|NA|NA MAG.T2.48_00943 247490.KSU1_D0548 6.3e-77 294.7 Planctomycetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IWXH@203682,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T2.48_00944 247490.KSU1_D0549 2.4e-61 242.3 Planctomycetes hrtA ko:K02003,ko:K09810,ko:K09814 ko02010,map02010 M00255,M00257,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2IYS3@203682,COG1136@1,COG1136@2 NA|NA|NA V PFAM ABC transporter MAG.T2.48_00945 1123508.JH636439_gene960 2.2e-47 196.4 Planctomycetes ko:K01993 ko00000 Bacteria 2IYUX@203682,COG0845@1,COG0845@2 NA|NA|NA M PFAM secretion protein HlyD MAG.T2.48_00946 1124780.ANNU01000036_gene21 2.1e-09 69.7 Bacteroidetes Bacteria 4NW11@976,COG5661@1,COG5661@2 NA|NA|NA O secreted Zn-dependent protease MAG.T2.48_00947 1123035.ARLA01000028_gene1876 3.7e-10 72.0 Psychroflexus psrP1 Bacteria 1IKS9@117743,4C338@83612,4PPQZ@976,COG2133@1,COG2133@2,COG2374@1,COG2374@2 NA|NA|NA G pyrroloquinoline quinone binding MAG.T2.48_00948 1142394.PSMK_11860 3.6e-81 308.9 Planctomycetes pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_0056 Bacteria 2IYEZ@203682,COG1995@1,COG1995@2 NA|NA|NA H Belongs to the PdxA family MAG.T2.48_00949 1142394.PSMK_18920 8.3e-202 710.3 Planctomycetes tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2J56J@203682,COG0021@1,COG0021@2 NA|NA|NA H Transketolase, pyrimidine binding domain MAG.T2.48_00950 1210884.HG799462_gene8899 6.1e-65 255.4 Planctomycetes Bacteria 2J2KX@203682,COG2382@1,COG2382@2 NA|NA|NA P Putative esterase MAG.T2.48_00952 485915.Dret_1749 1.9e-37 162.5 Desulfovibrionales ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 ko00000,ko01000,ko03009 Bacteria 1MW1C@1224,2M9WQ@213115,2WP6B@28221,42T4F@68525,COG0293@1,COG0293@2 NA|NA|NA J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit MAG.T2.48_00953 497964.CfE428DRAFT_1483 1.8e-146 525.8 Verrucomicrobia dapL GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 46TMR@74201,COG0436@1,COG0436@2 NA|NA|NA E Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate MAG.T2.48_00954 344747.PM8797T_29178 7.7e-32 144.1 Planctomycetes Bacteria 2J4T8@203682,COG3963@1,COG3963@2 NA|NA|NA I Ribosomal RNA adenine dimethylase MAG.T2.48_00956 1166948.JPZL01000002_gene1318 1e-253 883.6 Gammaproteobacteria ko:K08676 ko00000,ko01000,ko01002 Bacteria 1R2MG@1224,1T5TC@1236,COG0793@1,COG0793@2,COG0823@1,COG0823@2 NA|NA|NA U WD40-like Beta Propeller Repeat MAG.T2.48_00957 926550.CLDAP_25100 1.1e-67 263.1 Chloroflexi ppa 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 2G6T4@200795,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions MAG.T2.48_00958 1121430.JMLG01000002_gene1113 4.7e-27 128.6 Peptococcaceae Bacteria 1UZH3@1239,24DEV@186801,265G9@186807,COG4279@1,COG4279@2 NA|NA|NA S SWIM zinc finger MAG.T2.48_00959 485913.Krac_10500 1.9e-206 726.5 Chloroflexi helZ 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2G5JY@200795,COG0553@1,COG0553@2 NA|NA|NA L SNF2 Helicase protein MAG.T2.48_00961 1142394.PSMK_28220 3.2e-18 99.0 Planctomycetes Bacteria 2IZYK@203682,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV MAG.T2.48_00962 1142394.PSMK_28200 3.5e-100 371.7 Planctomycetes xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2IX6A@203682,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily MAG.T2.48_00963 1469245.JFBG01000034_gene1426 6.6e-46 191.0 Chromatiales 2.1.1.72 ko:K00571,ko:K07316 ko00000,ko01000,ko02048 Bacteria 1MX9M@1224,1T62C@1236,1X1WS@135613,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase MAG.T2.48_00964 357808.RoseRS_1820 2.3e-101 375.9 Chloroflexia purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 2G5PV@200795,375PJ@32061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) MAG.T2.48_00965 477974.Daud_1973 4.1e-60 237.7 Peptococcaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,24HCB@186801,261MR@186807,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T2.48_00966 234267.Acid_3971 9.3e-112 410.6 Acidobacteria ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 3Y308@57723,COG1252@1,COG1252@2 NA|NA|NA C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase MAG.T2.48_00967 1283283.ATXA01000003_gene1585 3.5e-91 342.4 Actinobacteria Bacteria 2GIUM@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily MAG.T2.48_00968 1142394.PSMK_03170 4.6e-109 401.0 Planctomycetes ko:K07051 ko00000 Bacteria 2IXI8@203682,COG1099@1,COG1099@2 NA|NA|NA S with the TIM-barrel fold MAG.T2.48_00969 1142394.PSMK_13380 2.4e-07 63.5 Planctomycetes ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IWSH@203682,COG2165@1,COG2165@2 NA|NA|NA NU best DB hits PFAM PF00114 MAG.T2.48_00970 929556.Solca_2347 1.6e-60 240.0 Sphingobacteriia aspG GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 ko:K01424,ko:K01444,ko:K13051 ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 1IQZS@117747,4NE3D@976,COG1446@1,COG1446@2 NA|NA|NA E PFAM peptidase T2 asparaginase 2 MAG.T2.48_00971 319795.Dgeo_0666 1.1e-41 176.8 Deinococcus-Thermus MMAB 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 1WJ8A@1297,COG2096@1,COG2096@2 NA|NA|NA S PFAM Cobalamin adenosyltransferase MAG.T2.48_00972 1210884.HG799464_gene10726 1.8e-42 180.3 Planctomycetes hpaIM 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 2IWRP@203682,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family MAG.T2.48_00973 1033810.HLPCO_002589 3e-63 248.4 unclassified Bacteria upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 2NP5M@2323,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate MAG.T2.48_00974 1304885.AUEY01000096_gene2839 3.3e-200 705.3 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity MAG.T2.48_00976 1210884.HG799462_gene8065 1.8e-22 113.6 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.48_00977 1403819.BATR01000027_gene909 1.1e-79 304.7 Verrucomicrobiae Bacteria 2IV2P@203494,46X96@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_00978 1500890.JQNL01000001_gene763 2e-65 256.1 Xanthomonadales Bacteria 1MWJI@1224,1S2WT@1236,1X562@135614,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MAG.T2.48_00980 1163409.UUA_03883 1.5e-142 513.1 Xanthomonadales amnC 1.2.1.32,1.2.1.60,1.2.1.85 ko:K00151,ko:K10217 ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00569 R02762,R03889,R04418,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,1RMBQ@1236,1X3DG@135614,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T2.48_00981 583355.Caka_0069 1.3e-25 122.9 Verrucomicrobia Bacteria 46VWM@74201,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T2.48_00982 379066.GAU_3775 3.7e-294 1017.3 Gemmatimonadetes ccoO GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404,ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144,iIT341.HP0145 Bacteria 1ZU6U@142182,COG2993@1,COG2993@2,COG3278@1,COG3278@2 NA|NA|NA C Cytochrome C and Quinol oxidase polypeptide I MAG.T2.48_00984 595460.RRSWK_00580 5.1e-36 157.9 Planctomycetes ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 2J0TE@203682,COG2010@1,COG2010@2 NA|NA|NA C N-terminal domain of cytochrome oxidase-cbb3, FixP MAG.T2.48_00985 756272.Plabr_3049 5.3e-107 394.8 Planctomycetes ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IXC7@203682,COG0348@1,COG0348@2 NA|NA|NA C IG-like fold at C-terminal of FixG, putative oxidoreductase MAG.T2.48_00986 1379270.AUXF01000007_gene899 2.9e-08 65.5 Gemmatimonadetes fixH Bacteria 1ZUVU@142182,COG5456@1,COG5456@2 NA|NA|NA P FixH MAG.T2.48_00987 595460.RRSWK_00583 7.9e-21 107.8 Planctomycetes braZ ko:K09792 ko00000 Bacteria 2J05P@203682,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome C biogenesis protein transmembrane region MAG.T2.48_00988 379066.GAU_3781 1.9e-153 550.1 Gemmatimonadetes fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1ZU8D@142182,COG2217@1,COG2217@2,COG2608@1,COG2608@2 NA|NA|NA P Putative metal-binding domain of cation transport ATPase MAG.T2.48_00990 1218084.BBJK01000124_gene7010 2.3e-10 73.6 Burkholderiaceae Bacteria 1K3I0@119060,1N9DS@1224,2CN1D@1,2W87F@28216,32SG1@2 NA|NA|NA S Domain of unknown function (DUF4410) MAG.T2.48_00991 794903.OPIT5_16095 6.6e-40 171.0 Verrucomicrobia Bacteria 46SSC@74201,COG2755@1,COG2755@2 NA|NA|NA E PFAM lipolytic protein G-D-S-L family MAG.T2.48_00992 314230.DSM3645_13465 1.7e-153 550.8 Planctomycetes 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 2IXPN@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Cytochrome c MAG.T2.48_00994 1156919.QWC_04963 4.7e-72 278.5 Alcaligenaceae wbmJ Bacteria 1MYJ6@1224,2W9XG@28216,3T3K5@506,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T2.48_00995 1120919.AUBI01000001_gene3380 5.6e-23 115.9 Rhodospirillales ko:K03328 ko00000 2.A.66.2 Bacteria 1R9I0@1224,2JURV@204441,2U3NB@28211,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T2.48_00996 314225.ELI_02045 4.6e-38 165.2 Alphaproteobacteria 2.1.1.79 ko:K00574 ko00000,ko01000 Bacteria 1R61W@1224,2U3CB@28211,COG2230@1,COG2230@2 NA|NA|NA M Methyltransferase domain MAG.T2.48_00997 388051.AUFE01000096_gene3031 2.7e-81 308.9 Bacteria Bacteria 2ACTX@1,312EV@2 NA|NA|NA MAG.T2.48_00999 1156919.QWC_04938 4.7e-32 144.8 Alcaligenaceae hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4X@1224,2W2FN@28216,3T57U@506,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR MAG.T2.48_01000 411684.HPDFL43_01685 7.6e-61 240.7 Phyllobacteriaceae ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUS0@1224,2TQXD@28211,43GYG@69277,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit MAG.T2.48_01001 485917.Phep_2409 2.1e-38 167.9 Bacteroidetes Bacteria 2BD8Y@1,326X9@2,4P62X@976 NA|NA|NA MAG.T2.48_01003 794903.OPIT5_18805 9.2e-59 234.2 Opitutae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 3K9HB@414999,46VAM@74201,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 MAG.T2.48_01004 1142394.PSMK_23120 1.7e-112 412.5 Planctomycetes fcl 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 R05692 RC01014 ko00000,ko00001,ko01000 Bacteria 2IYBF@203682,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction MAG.T2.48_01005 1142394.PSMK_23130 9e-142 510.0 Planctomycetes gmd GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 R00888 RC00402 ko00000,ko00001,ko01000 Bacteria 2IWZ4@203682,COG1089@1,COG1089@2 NA|NA|NA M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose MAG.T2.48_01006 1287276.X752_06650 5.1e-20 105.1 Phyllobacteriaceae Bacteria 1PE0X@1224,2V82F@28211,43QPW@69277,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T2.48_01007 123899.JPQP01000021_gene3660 1.1e-107 396.7 Alcaligenaceae tilS 6.3.4.19 ko:K04075,ko:K14058 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1NKHX@1224,2VJ4Q@28216,3T6UE@506,COG0037@1,COG0037@2 NA|NA|NA D ATPase of the PP-loop superfamily implicated in cell cycle control MAG.T2.48_01008 1163407.UU7_13903 2.3e-79 302.0 Xanthomonadales 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV6W@1224,1RMMN@1236,1X4X0@135614,COG2148@1,COG2148@2 NA|NA|NA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis MAG.T2.48_01009 1123377.AUIV01000013_gene2300 5.8e-174 617.1 Xanthomonadales Bacteria 1MWKY@1224,1RYF4@1236,1X9F7@135614,COG1086@1,COG1086@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T2.48_01010 1123377.AUIV01000013_gene2297 1.8e-143 515.8 Xanthomonadales 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1MUPN@1224,1RPFX@1236,1X974@135614,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T2.48_01011 314225.ELI_13360 2.4e-105 389.8 Alphaproteobacteria Bacteria 1MY5T@1224,2TSZW@28211,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase MAG.T2.48_01012 713587.THITH_05815 3.4e-129 468.4 Gammaproteobacteria Bacteria 1R94Z@1224,1RQ74@1236,COG3919@1,COG3919@2 NA|NA|NA T ATP-grasp MAG.T2.48_01013 1255043.TVNIR_0704 9.4e-17 94.0 Bacteria yfhB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0031224,GO:0031226,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K18697 ko00564,map00564 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria COG0560@1,COG0560@2 NA|NA|NA E Phosphoserine phosphatase MAG.T2.48_01014 216596.RL0818 2.5e-76 292.7 Rhizobiaceae tilS 6.3.4.19 ko:K04075,ko:K14058 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1NKHX@1224,2TVKU@28211,4BC25@82115,COG0037@1,COG0037@2 NA|NA|NA D ATPase of the PP-loop superfamily implicated in cell cycle control MAG.T2.48_01015 765913.ThidrDRAFT_2639 7.7e-127 460.3 Chromatiales wbpB 1.1.1.335 ko:K13016 ko00520,map00520 R10140 RC00182 ko00000,ko00001,ko01000,ko01005 Bacteria 1PDW7@1224,1RPU8@1236,1X2BR@135613,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T2.48_01016 314278.NB231_16778 2.3e-62 245.4 Chromatiales wbpD 2.3.1.201 ko:K13018 ko00520,map00520 R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 Bacteria 1MZV9@1224,1RXAQ@1236,1WXX9@135613,COG0110@1,COG0110@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase MAG.T2.48_01017 1255043.TVNIR_0691 2e-145 522.3 Chromatiales degT 2.6.1.98 ko:K13017 ko00520,map00520 R10141 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1MUPN@1224,1RMCS@1236,1WWP0@135613,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T2.48_01019 575540.Isop_3742 7.3e-141 507.3 Planctomycetes wbpA 1.1.1.136,1.1.1.336 ko:K02472,ko:K02474,ko:K13015 ko00520,ko05111,map00520,map05111 R00421,R03317,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 Bacteria 2IXVX@203682,COG0677@1,COG0677@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T2.48_01020 756272.Plabr_0350 1.9e-123 449.9 Planctomycetes cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IX9C@203682,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T2.48_01021 1267533.KB906737_gene1692 1.5e-20 105.5 Acidobacteriia Bacteria 2JJE8@204432,3Y4US@57723,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T2.48_01024 1286631.X805_08080 9.4e-24 116.7 Betaproteobacteria Bacteria 1RJWF@1224,2VTQA@28216,COG5642@1,COG5642@2 NA|NA|NA S Protein of unknown function (DUF2384) MAG.T2.48_01025 69042.WH5701_08299 9e-28 130.2 Synechococcus Bacteria 1GH5N@1117,1H3B5@1129,COG5654@1,COG5654@2 NA|NA|NA S RES MAG.T2.48_01026 1142394.PSMK_07350 7.9e-34 150.6 Planctomycetes coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2J02E@203682,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A MAG.T2.48_01027 247490.KSU1_C0414 1.5e-150 539.7 Planctomycetes rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 2IXV3@203682,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T2.48_01030 1142394.PSMK_08310 6.3e-168 597.0 Planctomycetes tuf ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 2IXC2@203682,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis MAG.T2.48_01031 1142394.PSMK_08320 5.3e-15 86.3 Planctomycetes rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J1HX@203682,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family MAG.T2.48_01033 1142394.PSMK_08330 1.4e-13 82.8 Planctomycetes secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2J0E7@203682,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation MAG.T2.48_01034 1142394.PSMK_08340 2.5e-69 269.2 Planctomycetes nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2IZ9N@203682,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination MAG.T2.48_01036 1142394.PSMK_00130 2.8e-54 219.2 Planctomycetes ubiA 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IX4Z@203682,COG0382@1,COG0382@2 NA|NA|NA H COG0382 4-hydroxybenzoate polyprenyltransferase and related MAG.T2.48_01037 504728.K649_09200 1.2e-57 230.3 Bacteria ko:K08714 ko00000,ko02000 1.A.1.14 Bacteria 2Z7ZD@2,COG1226@1 NA|NA|NA P Ion transport protein MAG.T2.48_01039 290397.Adeh_0024 1.3e-203 716.1 Myxococcales proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MU7E@1224,2WJVC@28221,2YU5X@29,42ME5@68525,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) MAG.T2.48_01040 452637.Oter_1240 1.1e-07 62.4 Opitutae Bacteria 2EK6E@1,33DWT@2,3K8CQ@414999,46ZJP@74201 NA|NA|NA S Protein of unknown function (DUF3185) MAG.T2.48_01042 1142394.PSMK_00140 1.2e-39 169.9 Planctomycetes ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZBH@203682,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN MAG.T2.48_01044 521674.Plim_0454 4.1e-09 68.6 Bacteria 1.3.7.14,1.3.7.15 ko:K03088,ko:K11333 ko00860,ko01110,map00860,map01110 R09053,R09060 RC01008 ko00000,ko00001,ko01000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.48_01046 926569.ANT_10740 2.4e-67 263.8 Chloroflexi ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2G7VX@200795,COG2304@1,COG2304@2 NA|NA|NA S VWA domain containing CoxE-like protein MAG.T2.48_01047 1121912.AUHD01000006_gene1335 3.1e-62 246.1 Flavobacteriia Bacteria 1HY72@117743,4NEGD@976,COG2304@1,COG2304@2 NA|NA|NA P von Willebrand factor, type A MAG.T2.48_01048 70448.Q019X0 4.4e-164 584.7 Chlorophyta GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009791,GO:0009908,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0034641,GO:0034645,GO:0034660,GO:0035670,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048467,GO:0048481,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0061458,GO:0071704,GO:0090304,GO:0090567,GO:0099402,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Viridiplantae 34GPK@3041,37PE4@33090,COG0143@1,KOG0436@2759 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T2.48_01052 1340493.JNIF01000003_gene4550 5.4e-111 407.5 Bacteria metF 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria COG0685@1,COG0685@2 NA|NA|NA E methylenetetrahydrofolate reductase (NAD(P)H) activity MAG.T2.48_01053 530564.Psta_1966 6.6e-50 204.1 Planctomycetes rex GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K01926 ko00000,ko03000 Bacteria 2IZG6@203682,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state MAG.T2.48_01056 237368.SCABRO_03959 1.6e-21 109.8 Planctomycetes Bacteria 2J0EH@203682,COG3023@1,COG3023@2 NA|NA|NA V N-acetylmuramoyl-L-alanine amidase MAG.T2.48_01057 1142394.PSMK_29780 7.7e-54 217.6 Planctomycetes Bacteria 2IZHV@203682,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_01058 391625.PPSIR1_28298 7.6e-31 140.6 Deltaproteobacteria comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1RD1P@1224,2WR1E@28221,42UR6@68525,COG2131@1,COG2131@2 NA|NA|NA F MafB19-like deaminase MAG.T2.48_01060 1142394.PSMK_28460 6.9e-62 243.8 Planctomycetes clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2IXQN@203682,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T2.48_01061 1142394.PSMK_18100 6.5e-63 247.3 Planctomycetes clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2IYFK@203682,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T2.48_01062 1142394.PSMK_17230 6.4e-50 204.9 Planctomycetes fleS 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IWYR@203682,COG1716@1,COG1716@2,COG2203@1,COG2203@2,COG4191@1,COG4191@2 NA|NA|NA T GAF domain MAG.T2.48_01067 522306.CAP2UW1_0353 4e-185 654.4 Betaproteobacteria ko:K19172 ko00000,ko02048 Bacteria 1MWTW@1224,2VPYJ@28216,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T2.48_01068 471854.Dfer_3146 3e-106 392.5 Cytophagia Bacteria 47S7V@768503,4NKIR@976,COG2931@1,COG2931@2 NA|NA|NA Q SMART Integrin alpha beta-propellor repeat protein MAG.T2.48_01069 1123242.JH636434_gene3319 1.4e-29 138.3 Planctomycetes Bacteria 2J2W7@203682,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_01073 1112217.PPL19_03640 4.5e-130 471.5 Gammaproteobacteria astB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009015,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.23 ko:K01484 ko00330,ko01100,map00330,map01100 R04189 RC00024 ko00000,ko00001,ko01000 iECH74115_1262.ECH74115_2463,iECSP_1301.ECSP_2313,iECs_1301.ECs2451,iG2583_1286.G2583_2191 Bacteria 1MUJV@1224,1RNSS@1236,COG3724@1,COG3724@2 NA|NA|NA E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) MAG.T2.48_01074 1142394.PSMK_26480 1.4e-57 230.3 Planctomycetes holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IZVJ@203682,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III, delta' subunit MAG.T2.48_01075 756272.Plabr_0288 3.3e-08 66.6 Planctomycetes Bacteria 2CGC8@1,2J0H4@203682,32S3M@2 NA|NA|NA MAG.T2.48_01076 886293.Sinac_6369 2e-98 367.1 Planctomycetes 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2IXB2@203682,COG0551@1,COG0551@2 NA|NA|NA L Ca-dependent carbohydrate-binding module xylan-binding MAG.T2.48_01077 521674.Plim_0286 8.2e-111 407.5 Planctomycetes Bacteria 2IX87@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) MAG.T2.48_01079 246197.MXAN_0341 4.4e-152 545.0 Deltaproteobacteria kup ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1MUVH@1224,2WJEH@28221,42P5Y@68525,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell MAG.T2.48_01080 1144275.COCOR_04102 1.4e-23 117.1 Myxococcales Bacteria 1MVZS@1224,2WKHR@28221,2Z0V8@29,42QGY@68525,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family MAG.T2.48_01081 1396141.BATP01000025_gene931 6.2e-46 191.4 Verrucomicrobiae fieF Bacteria 2IUZU@203494,46SPJ@74201,COG0053@1,COG0053@2 NA|NA|NA P Dimerisation domain of Zinc Transporter MAG.T2.48_01082 316067.Geob_3261 2e-36 159.8 Deltaproteobacteria yfhR ko:K06889 ko00000 Bacteria 1RFAF@1224,2X601@28221,43AJV@68525,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T2.48_01083 1396418.BATQ01000058_gene93 2.4e-47 196.1 Verrucomicrobiae ko:K15256 ko00000,ko01000,ko03016 Bacteria 2IUZB@203494,46Z44@74201,COG0500@1,COG0500@2 NA|NA|NA Q Thiopurine S-methyltransferase (TPMT) MAG.T2.48_01084 388413.ALPR1_14379 1.8e-24 120.2 Cytophagia Bacteria 47K0Y@768503,4NG6K@976,COG4244@1,COG4244@2 NA|NA|NA G Protein of unknown function (DUF1549) MAG.T2.48_01088 497965.Cyan7822_5116 2.1e-51 211.1 Cyanothece 3.4.24.40 ko:K01406,ko:K21449 ko01503,map01503 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 Bacteria 1GC1J@1117,3KJVM@43988,COG2931@1,COG2931@2,COG3210@1,COG3210@2 NA|NA|NA QU Polymorphic membrane protein Chlamydia MAG.T2.48_01089 314230.DSM3645_11631 2.6e-41 175.6 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.48_01096 1123288.SOV_4c02530 4.1e-21 108.2 Negativicutes Bacteria 1VFU8@1239,2C2FS@1,3347I@2,4H7Z7@909932 NA|NA|NA S ASCH domain MAG.T2.48_01097 1173022.Cri9333_0447 1.1e-08 67.0 Oscillatoriales Bacteria 1G7PH@1117,1HHJH@1150,COG1403@1,COG1403@2 NA|NA|NA L HNH nucleases MAG.T2.48_01100 1396141.BATP01000024_gene878 2.3e-90 340.5 Bacteria sbcC GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576 ko:K03546 ko00000,ko03400 Bacteria COG0419@1,COG0419@2 NA|NA|NA L ATPase involved in DNA repair MAG.T2.48_01101 1123072.AUDH01000033_gene1991 6.2e-168 597.4 Alphaproteobacteria mloB Bacteria 1MXG1@1224,2U2ED@28211,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal MAG.T2.48_01102 575540.Isop_2445 9.4e-182 643.3 Planctomycetes 2.1.1.72 ko:K07319 ko00000,ko01000,ko02048 Bacteria 2IY0Z@203682,COG0863@1,COG0863@2,COG1475@1,COG1475@2 NA|NA|NA KL ParB-like nuclease domain MAG.T2.48_01109 575540.Isop_2452 9.5e-192 677.2 Planctomycetes Bacteria 2IXN3@203682,COG5525@1,COG5525@2 NA|NA|NA S Phage terminase large subunit (GpA) MAG.T2.48_01112 575540.Isop_2435 3.5e-128 465.3 Planctomycetes B Bacteria 2IZFA@203682,COG5511@1,COG5511@2 NA|NA|NA S Phage portal protein, lambda family MAG.T2.48_01113 575540.Isop_2434 6.9e-119 434.9 Planctomycetes ftsZ ko:K01932,ko:K03531,ko:K03980 ko04112,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko02048,ko03036,ko04812 2.A.66.4 Bacteria 2IX3F@203682,COG3087@1,COG3087@2 NA|NA|NA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides MAG.T2.48_01114 575540.Isop_2433 2.5e-26 124.8 Planctomycetes Bacteria 2J1PT@203682,COG5471@1,COG5471@2 NA|NA|NA S Uncharacterized conserved protein (DUF2190) MAG.T2.48_01115 575540.Isop_2432 6e-24 117.1 Planctomycetes Bacteria 2ETQX@1,2J1E8@203682,33M8I@2 NA|NA|NA MAG.T2.48_01119 1210884.HG799462_gene8269 1.2e-07 63.2 Planctomycetes Bacteria 298NR@1,2J4Q1@203682,2ZVTA@2 NA|NA|NA MAG.T2.48_01120 575540.Isop_2427 4.7e-26 124.4 Planctomycetes Bacteria 2CBV8@1,2J0Q1@203682,335SS@2 NA|NA|NA MAG.T2.48_01125 575540.Isop_2430 3.2e-20 105.1 Planctomycetes Bacteria 2EQKH@1,2J1DT@203682,33I6I@2 NA|NA|NA MAG.T2.48_01126 575540.Isop_2425 3.2e-60 240.0 Planctomycetes Bacteria 2J1F5@203682,COG5283@1,COG5283@2 NA|NA|NA MAG.T2.48_01127 575540.Isop_2424 4.2e-51 208.4 Planctomycetes Bacteria 2DN68@1,2J012@203682,32UID@2 NA|NA|NA MAG.T2.48_01131 864702.OsccyDRAFT_4039 8.6e-41 174.5 Bacteria ko:K07454 ko00000 Bacteria COG3440@1,COG3440@2 NA|NA|NA V regulation of methylation-dependent chromatin silencing MAG.T2.48_01132 864702.OsccyDRAFT_4038 1.8e-105 389.0 Oscillatoriales 2.1.1.113,2.1.1.37 ko:K00558,ko:K00590 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1G2AV@1117,1H9R9@1150,COG0863@1,COG0863@2 NA|NA|NA L DNA methylase MAG.T2.48_01136 1396141.BATP01000027_gene1066 3.6e-23 115.2 Bacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.48_01138 204669.Acid345_2310 7.6e-109 402.1 Acidobacteriia Bacteria 2JMN2@204432,3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA T Tetratricopeptide repeat MAG.T2.48_01139 1267535.KB906767_gene447 2e-124 453.8 Acidobacteriia Bacteria 2JMN2@204432,3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA T Tetratricopeptide repeat MAG.T2.48_01141 352165.HMPREF7215_1007 2.8e-123 448.7 Bacteria amyA 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH57 Bacteria COG1449@1,COG1449@2 NA|NA|NA G Belongs to the glycosyl hydrolase 57 family MAG.T2.48_01142 1142394.PSMK_29720 1.3e-38 166.4 Planctomycetes pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZA7@203682,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) MAG.T2.48_01143 344747.PM8797T_05845 6.4e-61 241.1 Planctomycetes Bacteria 2IZF5@203682,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T2.48_01147 1142394.PSMK_24070 7.4e-88 331.6 Planctomycetes ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2IY5J@203682,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle MAG.T2.48_01148 1340493.JNIF01000003_gene3403 8.8e-72 276.9 Bacteria ko:K06919 ko00000 Bacteria COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score MAG.T2.48_01150 1487953.JMKF01000069_gene94 3.4e-115 422.5 Bacteria dnaG 3.6.4.12 ko:K02314,ko:K02316 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T2.48_01151 314230.DSM3645_28012 8.5e-17 93.2 Bacteria Bacteria 2EMFK@1,33F4C@2 NA|NA|NA MAG.T2.48_01152 794903.OPIT5_04415 2.7e-156 558.5 Opitutae 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 3K8Y8@414999,46XT4@74201,COG3550@1,COG3550@2 NA|NA|NA S Pfam:HipA_N MAG.T2.48_01153 1415779.JOMH01000001_gene2200 2.3e-15 88.6 Xanthomonadales Bacteria 1QUPK@1224,1T4CG@1236,1XBJA@135614,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T2.48_01154 1265313.HRUBRA_02347 4.7e-66 258.5 Gammaproteobacteria oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1MU8Z@1224,1RNJ1@1236,COG0601@1,COG0601@2 NA|NA|NA P ABC-type dipeptide oligopeptide nickel transport systems, permease components MAG.T2.48_01156 926550.CLDAP_04870 4.2e-84 319.3 Chloroflexi Bacteria 2G62S@200795,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T2.48_01157 1142394.PSMK_27960 2.3e-84 320.1 Bacteria Bacteria COG1277@1,COG1277@2 NA|NA|NA MAG.T2.48_01158 1142394.PSMK_10520 1.5e-132 479.9 Planctomycetes rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2IX35@203682,COG1196@1,COG1196@2,COG1418@1,COG1418@2 NA|NA|NA D Endoribonuclease that initiates mRNA decay MAG.T2.48_01159 530564.Psta_2282 1.5e-48 199.9 Planctomycetes Bacteria 2C3WA@1,2J1GE@203682,2Z8P1@2 NA|NA|NA MAG.T2.48_01160 330214.NIDE0993 1.2e-48 200.3 Bacteria Bacteria COG0501@1,COG0501@2 NA|NA|NA O metalloendopeptidase activity MAG.T2.48_01162 272134.KB731326_gene229 2.4e-65 255.8 Cyanobacteria yxaA ko:K07090 ko00000 Bacteria 1G3K1@1117,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein MAG.T2.48_01164 523791.Kkor_1536 4.2e-114 418.7 Oceanospirillales Bacteria 1QCVP@1224,1RQFF@1236,1XICC@135619,COG5316@1,COG5316@2 NA|NA|NA S Domain of unknown function (DUF4139) MAG.T2.48_01165 1142394.PSMK_20510 2.3e-51 209.5 Planctomycetes ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2IYD7@203682,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits MAG.T2.48_01166 1142394.PSMK_14500 3.6e-25 121.3 Planctomycetes rsbW 2.7.11.1 ko:K04757,ko:K06379,ko:K08282 ko00000,ko01000,ko01001,ko03021 Bacteria 2J0BZ@203682,COG2172@1,COG2172@2 NA|NA|NA T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) MAG.T2.48_01167 1142394.PSMK_14510 1.2e-21 109.4 Planctomycetes ko:K04749 ko00000,ko03021 Bacteria 2J02R@203682,COG1366@1,COG1366@2 NA|NA|NA T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) MAG.T2.48_01168 1142394.PSMK_11750 4.6e-95 356.3 Planctomycetes ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2IY62@203682,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Belongs to the GSP D family MAG.T2.48_01169 1142394.PSMK_04770 3e-117 428.7 Planctomycetes carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 2IWSY@203682,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family MAG.T2.48_01170 1142394.PSMK_24470 1.6e-167 596.7 Planctomycetes priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IY1F@203682,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA MAG.T2.48_01171 1300143.CCAV010000007_gene3136 4.3e-19 103.2 Chryseobacterium CP_1075 Bacteria 1IIHW@117743,3ZQ5Q@59732,4NRK6@976,COG4886@1,COG4886@2,COG5563@1,COG5563@2 NA|NA|NA G endonuclease I MAG.T2.48_01174 743720.Psefu_1258 5.4e-32 144.4 Pseudomonas putida group pat 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1RGU8@1224,1S791@1236,1YVFA@136845,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain MAG.T2.48_01175 1121930.AQXG01000002_gene2374 7.8e-131 474.2 Sphingobacteriia baeB 3.1.2.6,3.4.21.102 ko:K01069,ko:K03797 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000,ko01002 Bacteria 1IUW3@117747,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T2.48_01176 1210884.HG799462_gene7812 2.5e-250 872.1 Planctomycetes sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 2IWRF@203682,COG0567@1,COG0567@2 NA|NA|NA C Dehydrogenase E1 component MAG.T2.48_01177 485918.Cpin_6839 1.2e-102 380.2 Sphingobacteriia sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 Bacteria 1IP4Q@117747,4NF33@976,COG0508@1,COG0508@2 NA|NA|NA C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) MAG.T2.48_01178 1283283.ATXA01000001_gene591 2.2e-63 250.4 Bacteria Bacteria COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase activity MAG.T2.48_01179 1191523.MROS_0933 5.2e-18 98.2 Bacteria Bacteria 2B9NZ@1,3231D@2 NA|NA|NA S Protein of unknown function (DUF1579) MAG.T2.48_01180 518766.Rmar_2078 4.2e-84 318.9 Bacteroidetes Order II. Incertae sedis sdcS ko:K14445 ko00000,ko02000 2.A.47.1 Bacteria 1FJTN@1100069,4NFDK@976,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region MAG.T2.48_01181 1142394.PSMK_21500 9.6e-83 314.7 Planctomycetes ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2IXEK@203682,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain MAG.T2.48_01183 521674.Plim_1787 2.1e-13 83.2 Planctomycetes Bacteria 2J1AN@203682,COG1652@1,COG1652@2 NA|NA|NA S Peptidoglycan-binding LysM MAG.T2.48_01184 1210884.HG799462_gene8202 1.4e-61 243.4 Planctomycetes rsmH 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2IXPV@203682,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA MAG.T2.48_01185 1142394.PSMK_22380 5.8e-72 278.5 Planctomycetes tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2IXZQ@203682,COG0472@1,COG0472@2 NA|NA|NA M UDP-N-acetylmuramyl pentapeptide MAG.T2.48_01186 357808.RoseRS_4100 1.1e-88 333.6 Chloroflexia arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011,ko:K12449 ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R01384,R01386,R02984,R07658,R07660 RC00026,RC00289,RC00508,RC01575,RC01811,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 iPC815.YPO2420,iSFV_1184.SFV_2325 Bacteria 2G64F@200795,374WM@32061,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase MAG.T2.48_01187 1142394.PSMK_22360 5.2e-51 209.5 Planctomycetes 2.7.10.2 ko:K08253,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 2J0AY@203682,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA D Capsular exopolysaccharide family MAG.T2.48_01188 323261.Noc_1987 2.1e-09 72.4 Chromatiales tadD ko:K20543 ko00000,ko02000 1.B.55.3 Bacteria 1MXMD@1224,1RSI5@1236,1WX0E@135613,COG0457@1,COG0457@2,COG5010@1,COG5010@2 NA|NA|NA U PEP-CTERM system TPR-repeat lipoprotein MAG.T2.48_01189 1142394.PSMK_22340 2.3e-23 116.3 Planctomycetes epsH Bacteria 2IZU8@203682,COG1269@1,COG1269@2 NA|NA|NA C PFAM Transmembrane exosortase (Exosortase_EpsH) MAG.T2.48_01190 1142394.PSMK_22340 1.7e-38 166.8 Planctomycetes epsH Bacteria 2IZU8@203682,COG1269@1,COG1269@2 NA|NA|NA C PFAM Transmembrane exosortase (Exosortase_EpsH) MAG.T2.48_01191 1142394.PSMK_22330 7.5e-69 268.5 Bacteria ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria COG1596@1,COG1596@2 NA|NA|NA M polysaccharide export MAG.T2.48_01192 1242864.D187_007544 9e-69 267.3 Myxococcales pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1MWAB@1224,2WJQR@28221,2YU78@29,42NMR@68525,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family MAG.T2.48_01193 314230.DSM3645_06739 9.3e-38 165.2 Planctomycetes Bacteria 2IYZF@203682,COG1572@1,COG1572@2 NA|NA|NA S Peptidase family C25 MAG.T2.48_01195 1121033.AUCF01000015_gene1403 1.1e-24 120.2 Rhodospirillales Bacteria 1RD94@1224,2JSF5@204441,2U7MY@28211,COG4186@1,COG4186@2 NA|NA|NA S Phosphoesterase or phosphohydrolase MAG.T2.48_01197 388413.ALPR1_14479 8.3e-86 324.3 Cytophagia 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 47K2Q@768503,4NF0B@976,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T2.48_01198 502025.Hoch_2065 5.1e-58 231.9 Myxococcales tqsA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 ko:K11744 ko00000 Bacteria 1MXXU@1224,2WJC6@28221,2YVSY@29,42P0U@68525,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T2.48_01199 1123508.JH636440_gene2523 1.3e-56 227.6 Planctomycetes Bacteria 2IWTK@203682,COG2206@1,COG2206@2 NA|NA|NA T HD domain MAG.T2.48_01200 1142394.PSMK_07950 2.4e-43 182.6 Bacteria Bacteria COG0705@1,COG0705@2 NA|NA|NA S proteolysis MAG.T2.48_01201 1201290.M902_2788 2.4e-19 104.0 Bacteria 3.4.24.3 ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity MAG.T2.48_01203 1267535.KB906767_gene2625 8.8e-32 142.9 Acidobacteriia trxA ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 iIT341.HP0824 Bacteria 2JJHK@204432,3Y53D@57723,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family MAG.T2.48_01204 633131.TR2A62_0030 1.5e-63 250.0 Alphaproteobacteria folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_3924,iPC815.YPO3501 Bacteria 1MUIR@1224,2TTMG@28211,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives MAG.T2.48_01206 246197.MXAN_2389 5e-44 184.5 Myxococcales btuE 1.11.1.22,1.11.1.9 ko:K00432,ko:K20207 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 iJN678.slr1992 Bacteria 1RD1R@1224,2WNWS@28221,2YV4G@29,42S35@68525,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family MAG.T2.48_01207 1267005.KB911259_gene3953 7.1e-36 157.9 Bacteria 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria COG2203@1,COG2203@2 NA|NA|NA T Gaf domain MAG.T2.48_01208 1379698.RBG1_1C00001G1403 1.5e-83 317.0 unclassified Bacteria Bacteria 2NNSP@2323,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T2.48_01209 1239962.C943_00050 2e-103 383.6 Cytophagia 3.4.17.21 ko:K01301 ko00000,ko01000,ko01002 Bacteria 47MK3@768503,4NI5W@976,COG2234@1,COG2234@2 NA|NA|NA S glutamate carboxypeptidase MAG.T2.48_01210 1047013.AQSP01000120_gene964 9.4e-75 288.1 unclassified Bacteria msrA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136 1.8.4.11,1.8.4.12,6.1.1.1 ko:K01866,ko:K07304,ko:K07305,ko:K12267 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2NPBE@2323,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T2.48_01211 483219.LILAB_18130 1.1e-48 200.3 Myxococcales truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 1MV0N@1224,2WKWY@28221,2YVB2@29,42MU5@68525,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs MAG.T2.48_01214 1158292.JPOE01000002_gene3087 2.7e-75 288.5 unclassified Burkholderiales Bacteria 1KN9X@119065,1MU1W@1224,2VHF9@28216,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain MAG.T2.48_01215 1038869.AXAN01000003_gene2702 1e-27 129.8 Burkholderiaceae yybH Bacteria 1K874@119060,1PX5Y@1224,2WCP2@28216,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T2.48_01216 1479238.JQMZ01000001_gene2539 1e-65 256.5 Alphaproteobacteria Bacteria 1R5UU@1224,2U45H@28211,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain MAG.T2.48_01217 34007.IT40_17045 1.6e-71 275.8 Paracoccus ko:K16137 ko00000,ko03000 Bacteria 1PDYH@1224,2PY0D@265,2V7WH@28211,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T2.48_01219 1291050.JAGE01000001_gene415 2.6e-73 282.3 Ruminococcaceae f42a Bacteria 1TRN5@1239,248UU@186801,3WI4C@541000,COG0330@1,COG0330@2 NA|NA|NA O SPFH Band 7 PHB domain protein MAG.T2.48_01220 338966.Ppro_2542 6.7e-07 61.2 Proteobacteria Bacteria 1NGKD@1224,2EFX2@1,339PA@2 NA|NA|NA S PEP-CTERM motif MAG.T2.48_01221 1192034.CAP_8932 4.6e-41 174.5 Myxococcales Bacteria 1QE0P@1224,2WPW5@28221,2Z2TG@29,42TDZ@68525,COG3861@1,COG3861@2 NA|NA|NA S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity MAG.T2.48_01222 497964.CfE428DRAFT_5593 2.9e-14 85.5 Bacteria Bacteria COG2823@1,COG2823@2 NA|NA|NA S hyperosmotic response MAG.T2.48_01223 1123508.JH636439_gene879 4.3e-159 568.5 Planctomycetes Bacteria 2IXKJ@203682,COG0526@1,COG0526@2 NA|NA|NA CO EF hand MAG.T2.48_01224 1142394.PSMK_25120 1.5e-27 129.8 Planctomycetes lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2J0RI@203682,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins MAG.T2.48_01225 1142394.PSMK_25130 1.6e-19 104.0 Bacteria ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria COG1734@1,COG1734@2 NA|NA|NA T zinc ion binding MAG.T2.48_01226 1142394.PSMK_05800 3.4e-111 408.3 Planctomycetes accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accA Bacteria 2IX7N@203682,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA MAG.T2.48_01227 266265.Bxe_A3982 2.1e-37 162.9 Burkholderiaceae proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1JZPH@119060,1R5J1@1224,2VJD1@28216,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline MAG.T2.48_01228 1396141.BATP01000003_gene4869 3.2e-38 166.0 Verrucomicrobiae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVXU@203494,46XHK@74201,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component MAG.T2.48_01229 1396141.BATP01000003_gene4868 3.4e-82 312.0 Verrucomicrobiae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVHQ@203494,46SHV@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T2.48_01230 1142394.PSMK_15140 1.1e-162 580.5 Planctomycetes ubiD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_4669,iIT341.HP0396 Bacteria 2IYCA@203682,COG0043@1,COG0043@2 NA|NA|NA H COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and MAG.T2.48_01232 1142394.PSMK_17220 5.2e-56 224.2 Planctomycetes ndhJ GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0050136,GO:0055114,GO:0071944 1.6.5.3 ko:K00332,ko:K05581,ko:K13378 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iJN678.ndhJ Bacteria 2IZSU@203682,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_01233 1121904.ARBP01000005_gene4880 2.7e-92 345.9 Bacteroidetes Bacteria 4NFM8@976,COG1748@1,COG1748@2 NA|NA|NA E Saccharopine dehydrogenase MAG.T2.48_01234 497964.CfE428DRAFT_3418 2.2e-39 168.7 Bacteria Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.48_01235 285514.JNWO01000002_gene5326 3.6e-79 301.6 Actinobacteria Bacteria 2I3BB@201174,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T2.48_01236 1123242.JH636436_gene139 9.8e-75 287.0 Planctomycetes ko:K07098 ko00000 Bacteria 2J0HU@203682,COG1408@1,COG1408@2 NA|NA|NA S metallophosphoesterase MAG.T2.48_01237 497964.CfE428DRAFT_1706 3.2e-98 365.2 Bacteria Bacteria COG4188@1,COG4188@2 NA|NA|NA KT dienelactone hydrolase MAG.T2.48_01238 1278073.MYSTI_01900 2.4e-39 168.7 Proteobacteria Bacteria 1N4JG@1224,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T2.48_01239 1121015.N789_09570 7.3e-16 91.3 Xanthomonadales yfeK Bacteria 1NBRM@1224,1SCY3@1236,1X8E5@135614,2CKE6@1,32ZEV@2 NA|NA|NA S Family of unknown function (DUF5329) MAG.T2.48_01240 314230.DSM3645_21854 8.2e-93 347.4 Planctomycetes aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 2IY2Z@203682,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system MAG.T2.48_01241 391625.PPSIR1_16615 3.8e-71 275.0 Deltaproteobacteria ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUX3@1224,2X7BN@28221,42S2J@68525,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein MAG.T2.48_01242 1122134.KB893650_gene1142 1.9e-64 253.4 Oceanospirillales sagI ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1PM1H@1224,1RUN8@1236,1XQN3@135619,COG0842@1,COG0842@2,COG1511@1,COG1511@2 NA|NA|NA V ABC-2 family transporter protein MAG.T2.48_01243 1183438.GKIL_0081 1.8e-48 198.7 Cyanobacteria gloA 3.2.2.1 ko:K01239,ko:K08234 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1GDK3@1117,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase MAG.T2.48_01245 1123508.JH636443_gene5005 2e-32 145.2 Planctomycetes Bacteria 2J0DW@203682,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T2.48_01246 1123508.JH636443_gene5006 9.5e-54 216.5 Planctomycetes Bacteria 2IZKB@203682,COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity MAG.T2.48_01247 261292.Nit79A3_3374 8.1e-38 163.3 Nitrosomonadales Bacteria 1MWQD@1224,2VK8E@28216,373VA@32003,COG1672@1,COG1672@2 NA|NA|NA S SMART ATPase, AAA type, core MAG.T2.48_01249 416348.Hlac_3635 1.3e-21 109.8 Archaea ko:K07494 ko00000 Archaea COG3335@1,arCOG02129@2157 NA|NA|NA L Transposase and inactivated derivatives MAG.T2.48_01250 1380394.JADL01000014_gene224 2.4e-55 223.0 Rhodospirillales oxdD 4.1.1.2 ko:K01569 ko00630,ko01100,map00630,map01100 R00522 RC00321 ko00000,ko00001,ko01000 Bacteria 1MUZA@1224,2JV4E@204441,2TTMU@28211,COG2140@1,COG2140@2 NA|NA|NA G Cupin MAG.T2.48_01251 180281.CPCC7001_2735 2.3e-197 695.3 Cyanobium Bacteria 1G49Q@1117,22TNQ@167375,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T2.48_01253 314230.DSM3645_26749 1.8e-33 149.4 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2IZAB@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.48_01254 1396141.BATP01000060_gene4560 2.2e-124 453.8 Verrucomicrobiae Bacteria 2IV44@203494,46UAE@74201,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_01255 290397.Adeh_3989 1.6e-71 276.9 Myxococcales Bacteria 1MWYR@1224,2WN11@28221,2YU83@29,42RD4@68525,COG2271@1,COG2271@2 NA|NA|NA G Organic Anion Transporter Polypeptide (OATP) family MAG.T2.48_01256 1142394.PSMK_05510 9.3e-108 397.9 Planctomycetes aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 ko:K00014,ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1860 Bacteria 2IXKU@203682,COG0169@1,COG0169@2,COG0710@1,COG0710@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) MAG.T2.48_01258 1303518.CCALI_01261 7.7e-57 227.6 Bacteria phhA GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 R01795,R07211 RC00490 ko00000,ko00001,ko01000 Bacteria COG3186@1,COG3186@2 NA|NA|NA E Phenylalanine-4-hydroxylase MAG.T2.48_01259 1123389.ATXJ01000032_gene1674 4.6e-70 271.9 Deinococcus-Thermus ko:K07133 ko00000 Bacteria 1WIG0@1297,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T2.48_01260 1379698.RBG1_1C00001G1631 2.5e-76 292.7 unclassified Bacteria pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2NP8P@2323,COG0006@1,COG0006@2 NA|NA|NA E Metallopeptidase family M24 MAG.T2.48_01262 1123242.JH636434_gene4081 3.8e-271 940.6 Planctomycetes thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c45100,iYO844.BSU08790 Bacteria 2IWV7@203682,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction MAG.T2.48_01264 448385.sce3847 4e-96 358.2 Myxococcales tdcB 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVWJ@1224,2WM9K@28221,2YV33@29,42MKY@68525,COG1171@1,COG1171@2 NA|NA|NA E Threonine dehydratase MAG.T2.48_01266 756067.MicvaDRAFT_3190 3.6e-15 90.5 Oscillatoriales Bacteria 1G2XZ@1117,1HEEK@1150,COG2931@1,COG2931@2,COG3266@1,COG3266@2 NA|NA|NA Q Integrin alpha (beta-propellor repeats). MAG.T2.48_01267 1142394.PSMK_12700 1.2e-70 275.0 Planctomycetes Bacteria 2IYMX@203682,COG0457@1,COG0457@2 NA|NA|NA O Tetratricopeptide repeat MAG.T2.48_01269 667014.Thein_1877 2e-89 336.3 Thermodesulfobacteria ribB GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iJN746.PP_0516,iSB619.SA_RS08945 Bacteria 2GHPG@200940,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate MAG.T2.48_01270 1142394.PSMK_27020 2.9e-51 209.5 Bacteria Bacteria COG1363@1,COG1363@2 NA|NA|NA G aminopeptidase activity MAG.T2.48_01271 1379698.RBG1_1C00001G1527 3.2e-75 289.7 unclassified Bacteria 3.4.21.66 ko:K08651 ko00000,ko01000,ko01002,ko03110 Bacteria 2NPDC@2323,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 MAG.T2.48_01272 1254432.SCE1572_44265 1.2e-125 457.2 Myxococcales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 1MU4J@1224,2WKII@28221,2YU3K@29,42MTY@68525,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase MAG.T2.48_01275 886293.Sinac_2616 7.4e-122 443.7 Planctomycetes ko:K03924 ko00000,ko01000 Bacteria 2IY1M@203682,COG0714@1,COG0714@2 NA|NA|NA S ATPase associated with MAG.T2.48_01276 1142394.PSMK_01390 2.2e-21 110.9 Planctomycetes Bacteria 2IXP0@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A MAG.T2.48_01277 593907.Celgi_2266 4e-62 246.1 Actinobacteria recD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GIX1@201174,COG0507@1,COG0507@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD MAG.T2.48_01278 941449.dsx2_0640 5.4e-86 326.2 Desulfovibrionales recB 3.1.11.5,3.6.4.12 ko:K03406,ko:K03582,ko:K16898 ko02020,ko02030,ko03440,map02020,map02030,map03440 ko00000,ko00001,ko01000,ko02035,ko03400 Bacteria 1MUTF@1224,2MDJT@213115,2WJ30@28221,42NKH@68525,COG1074@1,COG1074@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA MAG.T2.48_01279 1125863.JAFN01000001_gene3424 7.3e-79 302.8 Deltaproteobacteria recC 3.1.11.5 ko:K03583 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWTI@1224,2WJ4Q@28221,42N6G@68525,COG1330@1,COG1330@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity MAG.T2.48_01280 1182590.BN5_00645 2.2e-127 463.0 Pseudomonas aeruginosa group sulP GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 1MVWV@1224,1RMCN@1236,1YI4B@136841,COG0659@1,COG0659@2 NA|NA|NA U Sulfate permease family MAG.T2.48_01281 1122182.KB903825_gene245 4.8e-35 154.8 Micromonosporales ko:K07010 ko00000,ko01002 Bacteria 2GIV6@201174,4DD3J@85008,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 MAG.T2.48_01282 1210884.HG799464_gene10806 7e-33 147.5 Planctomycetes msrB 1.8.4.11,1.8.4.12 ko:K12267 ko00000,ko01000 Bacteria 2J06Z@203682,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.48_01283 530564.Psta_2731 6.1e-68 265.0 Planctomycetes Bacteria 2IZ9I@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T2.48_01284 937777.Deipe_1263 1.8e-25 123.6 Deinococcus-Thermus 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1WM52@1297,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T2.48_01285 1123368.AUIS01000014_gene2302 4.2e-139 501.5 Gammaproteobacteria Bacteria 1P235@1224,1SZYR@1236,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase MAG.T2.48_01286 1303518.CCALI_00760 9.3e-189 667.5 Bacteria ko:K06978 ko00000 Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T2.48_01287 1007104.SUS17_2352 2.2e-176 625.9 Sphingomonadales 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria 1MUJ3@1224,2K37J@204457,2TUZZ@28211,COG1506@1,COG1506@2 NA|NA|NA E X-Pro dipeptidyl-peptidase (S15 family) MAG.T2.48_01288 452637.Oter_0935 2.4e-64 252.7 Opitutae dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K05540 ko00000,ko01000,ko03016 Bacteria 3K895@414999,46TCT@74201,COG0042@1,COG0042@2 NA|NA|NA H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T2.48_01291 1142394.PSMK_31070 1.4e-43 183.3 Planctomycetes scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 2IZNB@203682,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves MAG.T2.48_01292 886293.Sinac_6881 5.1e-13 80.9 Planctomycetes atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2J00X@203682,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane MAG.T2.48_01293 861299.J421_3996 1.3e-26 126.3 Gemmatimonadetes cyaA GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1ZTYF@142182,COG2954@1,COG2954@2,COG5607@1,COG5607@2 NA|NA|NA S CYTH MAG.T2.48_01294 1142394.PSMK_07410 2.3e-53 216.5 Planctomycetes holB 2.7.7.7 ko:K02341,ko:K02343,ko:K09384 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IZ3J@203682,COG0470@1,COG0470@2 NA|NA|NA L COG2812 DNA polymerase III, gamma tau subunits MAG.T2.48_01301 1267533.KB906737_gene1627 1.9e-29 134.8 Acidobacteriia 1.18.1.2,1.19.1.1 ko:K00528,ko:K05524 R10159 ko00000,ko01000 Bacteria 2JJRG@204432,3Y59N@57723,COG1146@1,COG1146@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T2.48_01302 1231392.OCGS_1763 1.9e-37 162.9 Alphaproteobacteria dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215,ko:K03546 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0510,iLJ478.TM1520,iSbBS512_1146.SbBS512_E0035 Bacteria 1MUCT@1224,2TSFJ@28211,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate MAG.T2.48_01303 649638.Trad_1004 1.3e-67 263.8 Deinococcus-Thermus ko:K07263 ko00000,ko01000,ko01002 Bacteria 1WIM9@1297,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T2.48_01305 37919.EP51_01190 6e-10 70.9 Nocardiaceae 3.4.21.107 ko:K04771,ko:K08372 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2GJ96@201174,4G6JK@85025,COG0265@1,COG0265@2 NA|NA|NA M PDZ domain (Also known as DHR or GLGF) MAG.T2.48_01307 690850.Desaf_2317 4.8e-54 218.4 Desulfovibrionales ydeD Bacteria 1N024@1224,2M8R7@213115,2WJEJ@28221,42NW9@68525,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T2.48_01311 314230.DSM3645_27331 5.2e-75 291.6 Planctomycetes gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria 2IX4B@203682,COG1450@1,COG1450@2 NA|NA|NA NU general secretion pathway protein D MAG.T2.48_01313 314230.DSM3645_27348 4.3e-08 66.6 Planctomycetes ko:K02662 ko00000,ko02035,ko02044 Bacteria 2IZK7@203682,COG4972@1,COG4972@2 NA|NA|NA NU PFAM Fimbrial assembly family protein MAG.T2.48_01318 563040.Saut_0266 2.4e-13 82.4 Epsilonproteobacteria gspG ko:K02246,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1RDX2@1224,2YPMF@29547,42SFB@68525,COG2165@1,COG2165@2 NA|NA|NA U general secretion pathway protein G MAG.T2.48_01319 344747.PM8797T_14319 1.8e-74 286.6 Planctomycetes gspF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXYZ@203682,COG1459@1,COG1459@2 NA|NA|NA U Type 4 fimbrial assembly protein pilC MAG.T2.48_01320 861299.J421_3137 2.1e-280 971.8 Gemmatimonadetes clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1ZT9Z@142182,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE MAG.T2.48_01322 1142394.PSMK_10170 4.9e-212 744.2 Planctomycetes glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 2IXF9@203682,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source MAG.T2.48_01323 879310.HMPREF9162_1471 1.9e-19 102.8 Negativicutes ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,4H57W@909932,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family MAG.T2.48_01324 1142394.PSMK_18550 2.6e-39 169.9 Planctomycetes enhA_2 ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2J0C4@203682,COG1376@1,COG1376@2,COG1388@1,COG1388@2 NA|NA|NA M ErfK YbiS YcfS YnhG family protein MAG.T2.48_01326 1142394.PSMK_11720 1.4e-38 165.6 Planctomycetes queF 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 R07605 RC01875 ko00000,ko00001,ko01000,ko03016 Bacteria 2J07W@203682,COG0780@1,COG0780@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) MAG.T2.48_01327 264462.Bd1105 6.4e-57 228.0 Bdellovibrionales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1MVE3@1224,2MT7S@213481,2WMSH@28221,42M2I@68525,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T2.48_01328 1131553.JIBI01000012_gene827 7.2e-71 273.9 Nitrosomonadales ppgK 2.7.1.2,2.7.1.63,5.3.1.9 ko:K00845,ko:K00886,ko:K01810 ko00010,ko00030,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114,M00549 R00299,R01600,R01786,R02187,R02189,R02739,R02740,R03321 RC00002,RC00017,RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1NSQA@1224,2WC2A@28216,37479@32003,COG1940@1,COG1940@2 NA|NA|NA GK ROK family MAG.T2.48_01330 471852.Tcur_0851 4e-169 601.3 Streptosporangiales aldA 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4EH5D@85012,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.48_01331 1283283.ATXA01000007_gene3824 1.2e-67 263.5 Frankiales 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSN@201174,4EUCR@85013,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.48_01332 1142394.PSMK_16410 2e-55 224.6 Bacteria 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria COG1874@1,COG1874@2 NA|NA|NA G beta-galactosidase activity MAG.T2.48_01333 215803.DB30_7175 1.1e-40 172.9 Myxococcales amnD 3.5.99.5,4.1.1.77 ko:K01617,ko:K15067 ko00362,ko00380,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R03887,R05374 RC00751,RC01015,RC02672 ko00000,ko00001,ko00002,ko01000 Bacteria 1MYEM@1224,2X3V9@28221,2YX7P@29,438KW@68525,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP MAG.T2.48_01335 1379270.AUXF01000001_gene2448 2.1e-47 197.2 Bacteria Bacteria COG2706@1,COG2706@2 NA|NA|NA G 6-phosphogluconolactonase activity MAG.T2.48_01337 1142394.PSMK_22890 9.4e-42 178.3 Planctomycetes 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2IY6X@203682,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family MAG.T2.48_01338 530564.Psta_0115 1.7e-49 203.8 Planctomycetes tpl Bacteria 2IWZD@203682,COG1774@1,COG1774@2 NA|NA|NA S signal peptidase-like protein MAG.T2.48_01339 247490.KSU1_B0239 3.8e-96 359.0 Planctomycetes der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2IWXY@203682,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis MAG.T2.48_01340 1392490.JHZX01000001_gene628 1.9e-46 194.1 Flavobacteriia Bacteria 1I1YW@117743,4PKTY@976,COG3291@1,COG3291@2 NA|NA|NA S ASPIC and UnbV MAG.T2.48_01341 768671.ThimaDRAFT_1795 1.6e-39 169.1 Chromatiales tadA 3.5.4.3,3.5.4.33 ko:K01487,ko:K11991 ko00230,ko01100,map00230,map01100 R01676,R10223 RC00204,RC00477 ko00000,ko00001,ko01000,ko03016 Bacteria 1RHM4@1224,1S4RE@1236,1WY1Y@135613,COG0590@1,COG0590@2 NA|NA|NA FJ CMP dCMP deaminase, zinc-binding MAG.T2.48_01343 391587.KAOT1_21876 4e-18 100.1 Flavobacteriia ko:K13735,ko:K21449 ko05100,map05100 ko00000,ko00001,ko02000 1.B.40.2 Bacteria 1IMTN@117743,4PMF3@976,COG4886@1,COG4886@2,COG5492@1,COG5492@2 NA|NA|NA N Parallel beta-helix repeats MAG.T2.48_01344 661478.OP10G_0354 4.2e-45 188.0 Bacteria Bacteria COG4312@1,COG4312@2 NA|NA|NA S Bacterial protein of unknown function (DUF899) MAG.T2.48_01345 1301098.PKB_4828 4e-46 192.2 Gammaproteobacteria mdtN GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015546,GO:0015893,GO:0015906,GO:0022857,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0045117,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:1901474,GO:1901682,GO:1902599 ko:K03543,ko:K15549 M00701 ko00000,ko00002,ko02000 8.A.1.1,8.A.1.1.3 Bacteria 1MWG0@1224,1RP22@1236,COG1566@1,COG1566@2 NA|NA|NA V multidrug resistance MAG.T2.48_01347 697282.Mettu_3530 7.1e-69 268.5 Methylococcales ttgC Bacteria 1MWX5@1224,1RTUT@1236,1XGSK@135618,COG1538@1,COG1538@2 NA|NA|NA MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) MAG.T2.48_01349 243090.RB8562 5e-165 587.8 Planctomycetes gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 2IX1K@203682,COG0696@1,COG0696@2 NA|NA|NA F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate MAG.T2.48_01350 1142394.PSMK_29570 8.9e-64 250.8 Planctomycetes yggS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 ko:K06997 ko00000 Bacteria 2IZ9R@203682,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MAG.T2.48_01352 1142394.PSMK_10320 7.3e-59 234.2 Planctomycetes tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZHI@203682,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis MAG.T2.48_01353 1142394.PSMK_27240 7e-21 109.4 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.48_01354 452637.Oter_0260 2.1e-70 273.1 Opitutae Bacteria 3KA0E@414999,46YS9@74201,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T2.48_01355 1142394.PSMK_22930 1.3e-90 340.1 Planctomycetes fbpC 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 Bacteria 2IZ1J@203682,COG3842@1,COG3842@2 NA|NA|NA P PFAM ABC transporter MAG.T2.48_01357 234267.Acid_7677 1.9e-34 152.5 Acidobacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 3Y7UW@57723,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.48_01358 448385.sce0520 2.1e-08 67.0 Myxococcales Bacteria 1R0BE@1224,2X817@28221,2Z05E@29,43CTP@68525,COG3391@1,COG3391@2 NA|NA|NA E Stigma-specific protein, Stig1 MAG.T2.48_01359 1267533.KB906733_gene3472 3.1e-94 353.6 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_01360 1142394.PSMK_14230 3.1e-09 68.6 Bacteria Bacteria COG5512@1,COG5512@2 NA|NA|NA L Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives MAG.T2.48_01361 1123508.JH636445_gene6698 7.6e-33 146.7 Planctomycetes ybgC ko:K07107 ko00000,ko01000 Bacteria 2J0BH@203682,COG0824@1,COG0824@2 NA|NA|NA S thioesterase MAG.T2.48_01362 1142394.PSMK_15430 6.9e-50 205.3 Planctomycetes mnmE ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 2IWUB@203682,COG0486@1,COG0486@2 NA|NA|NA J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 MAG.T2.48_01363 1142394.PSMK_15440 5.8e-77 295.8 Planctomycetes ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2IYA0@203682,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins MAG.T2.48_01364 1142394.PSMK_14290 6e-87 327.4 Planctomycetes apaH Bacteria 2IYH6@203682,COG0639@1,COG0639@2 NA|NA|NA T COG0639 Diadenosine tetraphosphatase and related MAG.T2.48_01365 756272.Plabr_1646 8.7e-88 331.3 Planctomycetes 2.1.1.80,2.7.13.3,3.1.1.61 ko:K07678,ko:K11527,ko:K13924 ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111 M00475,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 2J52D@203682,COG0642@1,COG0642@2,COG0784@1,COG0784@2,COG2202@1,COG2202@2 NA|NA|NA T COG0642 Signal transduction histidine kinase MAG.T2.48_01366 1142394.PSMK_08090 5.6e-150 537.7 Planctomycetes lpdA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IX5H@203682,COG1249@1,COG1249@2 NA|NA|NA C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) MAG.T2.48_01368 575540.Isop_1877 2e-37 162.5 Planctomycetes gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2IZYM@203682,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP MAG.T2.48_01369 575540.Isop_3342 9.9e-45 187.2 Planctomycetes lemA ko:K03744 ko00000 Bacteria 2IZBC@203682,COG1704@1,COG1704@2 NA|NA|NA S LemA family MAG.T2.48_01370 886293.Sinac_6493 2.1e-101 376.7 Planctomycetes htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 2IYND@203682,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T2.48_01372 221359.RS9916_31532 2.2e-48 199.1 Synechococcus gpm2 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 Bacteria 1GHMA@1117,1GYW1@1129,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase MAG.T2.48_01373 204669.Acid345_1426 5.4e-23 114.8 Acidobacteriia liuC 4.2.1.17,4.2.1.18,4.2.1.57 ko:K01692,ko:K13766,ko:K13779 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00036,M00087 R02085,R03026,R03045,R03493,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC00941,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 2JIII@204432,3Y3SE@57723,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T2.48_01376 1214166.ALLG01000022_gene193 2.4e-36 159.1 Streptococcus suis pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 1TRRX@1239,1WSP1@1307,4HCIJ@91061,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline MAG.T2.48_01377 240015.ACP_1661 1.2e-30 140.6 Acidobacteriia liuC 4.2.1.17,4.2.1.18,4.2.1.57 ko:K01692,ko:K13766,ko:K13779 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00036,M00087 R02085,R03026,R03045,R03493,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC00941,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 2JIII@204432,3Y3SE@57723,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T2.48_01379 1123360.thalar_03314 1.4e-18 100.5 Alphaproteobacteria yfcX 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9P@1224,2TS8E@28211,COG1024@1,COG1024@2,COG1250@1,COG1250@2 NA|NA|NA I enoyl-CoA hydratase MAG.T2.48_01380 472759.Nhal_1066 3.1e-233 814.7 Chromatiales ko:K06446 ko00930,ko01100,ko01120,map00930,map01100,map01120 R06943 RC00052 ko00000,ko00001,ko01000 Bacteria 1MUDR@1224,1RMMJ@1236,1WWVA@135613,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain MAG.T2.48_01381 562970.Btus_1308 4.3e-75 288.5 Alicyclobacillaceae ldh 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 Bacteria 1TQU2@1239,27949@186823,4HAB2@91061,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family MAG.T2.48_01382 1122176.KB903542_gene405 8.1e-27 127.1 Bacteria ko:K07025 ko00000 Bacteria COG1011@1,COG1011@2 NA|NA|NA S phosphatase activity MAG.T2.48_01383 886293.Sinac_4605 3.7e-102 378.6 Bacteria Bacteria COG5434@1,COG5434@2 NA|NA|NA M polygalacturonase activity MAG.T2.48_01384 215803.DB30_4561 3e-80 305.8 Myxococcales 1.3.1.45 ko:K05281 ko00943,ko01110,map00943,map01110 R06562,R06563,R07747,R07751 RC00805 ko00000,ko00001,ko01000 Bacteria 1RBSM@1224,2WTSY@28221,2YX8Q@29,42XUG@68525,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family MAG.T2.48_01385 257310.BB3952 5.3e-75 288.5 Alcaligenaceae ko:K03301 ko00000 2.A.12 Bacteria 1MVP5@1224,2VMB7@28216,3T3Q1@506,COG3202@1,COG3202@2 NA|NA|NA C Major facilitator MAG.T2.48_01387 1121405.dsmv_1098 2e-83 316.2 Desulfobacterales pdhA GO:0003674,GO:0005488,GO:0005515,GO:0140030,GO:0140032 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5R@1224,2MN0N@213118,2WJY1@28221,42NW8@68525,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component MAG.T2.48_01388 644966.Tmar_1672 2e-111 409.1 Clostridia pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iSB619.SA_RS05355,iYO844.BSU14590 Bacteria 1TP3J@1239,249UD@186801,COG0022@1,COG0022@2 NA|NA|NA C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit MAG.T2.48_01391 497964.CfE428DRAFT_2975 8.4e-200 704.1 Verrucomicrobia Bacteria 46TF8@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) MAG.T2.48_01392 530564.Psta_0232 1.2e-157 563.1 Planctomycetes Bacteria 2IY0X@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T2.48_01393 391625.PPSIR1_34707 6.4e-86 324.7 Proteobacteria Bacteria 1R5KK@1224,COG0491@1,COG0491@2 NA|NA|NA S COG0491 Zn-dependent hydrolases, including glyoxylases MAG.T2.48_01394 487521.OCU_20880 1.1e-57 231.5 Mycobacteriaceae gntK GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 2.7.1.12 ko:K00851,ko:K07028 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 R01737 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 23637@1762,2GM3U@201174,COG0645@1,COG0645@2,COG2187@1,COG2187@2 NA|NA|NA S AAA domain MAG.T2.48_01395 857087.Metme_3271 1.4e-21 110.2 Methylococcales actCD ko:K00185 ko00000 5.A.3 Bacteria 1NK6F@1224,1TI5B@1236,1XGJ3@135618,COG2010@1,COG2010@2 NA|NA|NA C Domain of unknown function (DUF4405) MAG.T2.48_01397 521045.Kole_0053 8e-161 575.1 Bacteria Bacteria 2ZAA2@2,arCOG06858@1 NA|NA|NA MAG.T2.48_01398 1123508.JH636444_gene5365 8.7e-43 180.6 Planctomycetes Bacteria 2J2X9@203682,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family MAG.T2.48_01399 357808.RoseRS_0010 2.8e-106 392.5 Chloroflexia Bacteria 2G8T5@200795,376FH@32061,COG0823@1,COG0823@2 NA|NA|NA U WD40-like Beta Propeller Repeat MAG.T2.48_01400 290397.Adeh_2584 9.3e-89 334.0 Myxococcales speB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFH@1224,2WIMR@28221,2Z373@29,42NBC@68525,COG0010@1,COG0010@2 NA|NA|NA E Arginase family MAG.T2.48_01401 205922.Pfl01_2158 1.2e-91 343.6 Pseudomonas fluorescens group ada 2.1.1.63,3.2.2.21 ko:K00567,ko:K10778,ko:K13529,ko:K13530,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1N2YQ@1224,1RPR3@1236,1YNZM@136843,COG0350@1,COG0350@2,COG2169@1,COG2169@2 NA|NA|NA FL Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated MAG.T2.48_01402 96561.Dole_2043 1.6e-22 114.4 Desulfobacterales Bacteria 1MZHI@1224,2MN6K@213118,2WUM4@28221,43BRC@68525,COG1800@1,COG1800@2,COG2885@1,COG2885@2,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats MAG.T2.48_01403 1123376.AUIU01000016_gene283 3.4e-20 105.9 Bacteria Bacteria COG3391@1,COG3391@2,COG4249@1,COG4249@2 NA|NA|NA S B-1 B cell differentiation MAG.T2.48_01404 1123072.AUDH01000004_gene541 3.6e-39 169.1 Rhodospirillales cheR 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 Bacteria 1MU6W@1224,2JQEI@204441,2TRQ3@28211,COG1352@1,COG1352@2 NA|NA|NA NT COG1352 Methylase of chemotaxis methyl-accepting proteins MAG.T2.48_01405 1210884.HG799468_gene13578 2e-77 296.2 Planctomycetes 3.1.1.61,3.5.1.44 ko:K03412,ko:K03413 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 2IX6F@203682,COG2201@1,COG2201@2 NA|NA|NA NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR MAG.T2.48_01406 1210884.HG799468_gene13577 4.5e-50 206.5 Planctomycetes ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 2J2K6@203682,COG0840@1,COG0840@2 NA|NA|NA NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). MAG.T2.48_01407 382464.ABSI01000012_gene2236 8.1e-14 84.0 Bacteria cheW ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria COG0835@1,COG0835@2 NA|NA|NA NT chemotaxis MAG.T2.48_01408 1210884.HG799468_gene13575 2.1e-180 639.8 Planctomycetes cheA 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 2IWWG@203682,COG0643@1,COG0643@2 NA|NA|NA T Signal transducing histidine kinase, homodimeric MAG.T2.48_01409 1210884.HG799468_gene13574 1.5e-29 136.7 Bacteria wspE 2.7.13.3 ko:K03407,ko:K13490 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00509 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria COG2198@1,COG2198@2 NA|NA|NA T Histidine kinase MAG.T2.48_01410 452637.Oter_0554 3.5e-122 445.3 Verrucomicrobia 6.5.1.1,6.5.1.6,6.5.1.7 ko:K07576,ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 46UFS@74201,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain MAG.T2.48_01411 243230.DR_1710 3.4e-21 107.5 Bacteria Bacteria 31CTK@2,arCOG05253@1 NA|NA|NA MAG.T2.48_01412 886293.Sinac_4662 1.3e-08 65.1 Planctomycetes ytjA Bacteria 2J16P@203682,COG5487@1,COG5487@2 NA|NA|NA S Protein of unknown function (DUF1328) MAG.T2.48_01413 589865.DaAHT2_0731 2.5e-65 256.1 Desulfobacterales ko:K07814 ko00000,ko02022 Bacteria 1MUB8@1224,2MIK0@213118,2WKKD@28221,42M4Y@68525,COG3437@1,COG3437@2 NA|NA|NA T HD domain MAG.T2.48_01414 518766.Rmar_0424 2.6e-48 200.3 Bacteroidetes Order II. Incertae sedis nhaP 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K03316 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.36,4.A.2.1 iJN678.sll0556 Bacteria 1FIVS@1100069,4PKJ5@976,COG0025@1,COG0025@2,COG0569@1,COG0569@2,COG1762@1,COG1762@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T2.48_01415 640081.Dsui_0423 4.3e-83 315.1 Rhodocyclales ydiK GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1MVX7@1224,2KW9W@206389,2VIIX@28216,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T2.48_01416 631362.Thi970DRAFT_04894 6.8e-36 158.3 Chromatiales Bacteria 1REG0@1224,1S9HA@1236,1WYWE@135613,295V5@1,2ZT65@2 NA|NA|NA MAG.T2.48_01418 1454004.AW11_01403 6.7e-123 448.0 Betaproteobacteria ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 1MWDF@1224,2VHKJ@28216,COG0659@1,COG0659@2 NA|NA|NA P Sulfate transporter antisigma-factor antagonist STAS MAG.T2.48_01419 595460.RRSWK_06361 1.7e-86 326.2 Planctomycetes Bacteria 2IZDI@203682,COG2335@1,COG2335@2 NA|NA|NA M COG2335 Secreted and surface protein containing fasciclin-like repeats MAG.T2.48_01420 401053.AciPR4_2363 9.1e-55 220.7 Acidobacteriia Bacteria 2JII9@204432,3Y2YB@57723,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T2.48_01423 1122164.JHWF01000014_gene1806 4.6e-282 977.6 Legionellales lmxF_2 ko:K03296 ko00000 2.A.6.2 Bacteria 1JCKK@118969,1MU48@1224,1RMBN@1236,COG0841@1,COG0841@2 NA|NA|NA U AcrB/AcrD/AcrF family MAG.T2.48_01424 1217718.ALOU01000093_gene1803 1e-50 207.6 Burkholderiaceae acrA ko:K03585,ko:K18094 ko01501,ko01503,ko02020,map01501,map01503,map02020 M00643,M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,2.A.6.2.21,2.A.6.2.24,8.A.1,8.A.1.6 Bacteria 1JZRN@119060,1MU78@1224,2VINC@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_01425 338963.Pcar_3093 1.5e-73 283.9 Deltaproteobacteria oprM_1 Bacteria 1MUA8@1224,2WIQX@28221,42MRU@68525,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM RND efflux system, outer membrane lipoprotein, NodT MAG.T2.48_01426 1198232.CYCME_1617 4.2e-20 105.9 Thiotrichales Bacteria 1NUVP@1224,1SNDK@1236,46293@72273,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function, DUF481 MAG.T2.48_01427 1142394.PSMK_05040 3.6e-35 155.2 Planctomycetes Bacteria 2IXDC@203682,COG0388@1,COG0388@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related MAG.T2.48_01428 478741.JAFS01000001_gene1893 2.2e-51 209.9 unclassified Verrucomicrobia ugtP 2.4.1.315 ko:K03429 ko00561,ko01100,map00561,map01100 R02689,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT28 Bacteria 37G9Z@326457,46SRU@74201,COG0707@1,COG0707@2 NA|NA|NA M Monogalactosyldiacylglycerol (MGDG) synthase MAG.T2.48_01429 450851.PHZ_c3310 3.8e-74 285.0 Caulobacterales lpxH_2 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MVKD@1224,2KG89@204458,2TSEB@28211,COG2908@1,COG2908@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain MAG.T2.48_01431 379066.GAU_2131 1.9e-144 518.8 Gemmatimonadetes dys 2.5.1.46 ko:K00809 ko00000,ko01000 Bacteria 1ZT1Z@142182,COG1899@1,COG1899@2 NA|NA|NA O Deoxyhypusine synthase MAG.T2.48_01434 1123508.JH636444_gene5461 8.9e-199 700.3 Planctomycetes speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iIT341.HP0422,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Bacteria 2IX6P@203682,COG1166@1,COG1166@2 NA|NA|NA H Catalyzes the biosynthesis of agmatine from arginine MAG.T2.48_01436 926566.Terro_4169 1.2e-128 467.2 Acidobacteriia hscA GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010467,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051604,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0097428,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1903506,GO:1990230,GO:1990234,GO:2001141 ko:K04043,ko:K04044 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33,1.A.33.1 Bacteria 2JIVF@204432,3Y2F8@57723,COG0443@1,COG0443@2 NA|NA|NA O heat shock protein 70 MAG.T2.48_01438 1142394.PSMK_20970 2.5e-132 479.9 Planctomycetes pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IX0Q@203682,COG0072@1,COG0072@2 NA|NA|NA J Phenylalanyl-tRNA synthetase, beta subunit MAG.T2.48_01439 390989.JOEG01000012_gene3325 1.9e-14 86.3 Micromonosporales fchA Bacteria 2IIRF@201174,4DG1Q@85008,COG3404@1,COG3404@2 NA|NA|NA E Formiminotransferase-cyclodeaminase MAG.T2.48_01440 1142394.PSMK_26980 9.1e-29 134.4 Bacteria Bacteria COG1073@1,COG1073@2 NA|NA|NA S thiolester hydrolase activity MAG.T2.48_01442 575540.Isop_2967 2.2e-70 272.7 Planctomycetes hhoA 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IYNW@203682,COG0265@1,COG0265@2 NA|NA|NA O C-terminal PDZ domain MAG.T2.48_01443 886293.Sinac_1932 6.1e-66 259.2 Planctomycetes Bacteria 2J55E@203682,COG2706@1,COG2706@2 NA|NA|NA G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.48_01444 344747.PM8797T_29778 5.1e-35 153.7 Planctomycetes ybjQ Bacteria 2J0RP@203682,COG0393@1,COG0393@2 NA|NA|NA S Putative heavy-metal-binding MAG.T2.48_01445 234267.Acid_6173 1.7e-123 449.1 Acidobacteria yhhW ko:K06911 ko00000 Bacteria 3Y367@57723,COG1741@1,COG1741@2 NA|NA|NA S Pirin C-terminal cupin domain MAG.T2.48_01446 929558.SMGD1_0008 6.9e-36 160.2 Epsilonproteobacteria ccmC Bacteria 1RG0A@1224,2YMXW@29547,42N37@68525,COG0755@1,COG0755@2,COG1333@1,COG1333@2 NA|NA|NA O Cytochrome c biogenesis protein MAG.T2.48_01447 472759.Nhal_0934 4.7e-43 181.8 Chromatiales ppiA 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1R9ZQ@1224,1S222@1236,1WYD7@135613,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.48_01448 1192034.CAP_3514 3e-32 145.2 Myxococcales ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1RINW@1224,2X3FI@28221,2YVVV@29,4385N@68525,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.48_01449 595460.RRSWK_04778 6.8e-98 365.9 Planctomycetes Bacteria 2IXZY@203682,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA T COG0515 Serine threonine protein MAG.T2.48_01450 926550.CLDAP_34280 2.4e-162 579.3 Chloroflexi pcd GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2G5JZ@200795,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T2.48_01451 344747.PM8797T_00397 1.1e-09 72.0 Bacteria Bacteria COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T2.48_01452 1142394.PSMK_22790 8.3e-81 307.4 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2IX9S@203682,COG1191@1,COG1191@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T2.48_01454 1303518.CCALI_00993 9.3e-50 204.1 Bacteria flhG ko:K02282,ko:K04562 ko00000,ko02035,ko02044 Bacteria COG0455@1,COG0455@2 NA|NA|NA D bacterial-type flagellum organization MAG.T2.48_01455 886293.Sinac_7410 2.6e-54 219.9 Planctomycetes flhF GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02404 ko00000,ko02035 Bacteria 2IYTZ@203682,COG1419@1,COG1419@2 NA|NA|NA N GTP-binding signal recognition particle SRP54 MAG.T2.48_01456 1142394.PSMK_22840 5.2e-181 641.3 Planctomycetes flhA ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 2IXQ9@203682,COG1298@1,COG1298@2 NA|NA|NA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin MAG.T2.48_01457 935863.AWZR01000004_gene518 1e-52 214.2 Xanthomonadales flhB ko:K02401,ko:K02556,ko:K03229,ko:K04061,ko:K13820 ko02020,ko02030,ko02040,ko03070,map02020,map02030,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02000,ko02035,ko02044 1.A.30.1,3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 1MUWI@1224,1RMHA@1236,1X529@135614,COG1377@1,COG1377@2 NA|NA|NA N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin MAG.T2.48_01458 1142394.PSMK_23500 1.6e-31 143.3 Planctomycetes fliR ko:K02421,ko:K13820 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 2J0P7@203682,COG1684@1,COG1684@2 NA|NA|NA N Flagellar biosynthesis pathway component FliR MAG.T2.48_01459 1142394.PSMK_23510 5.7e-11 73.6 Planctomycetes fliQ ko:K02420,ko:K03227 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2J17P@203682,COG1987@1,COG1987@2 NA|NA|NA N Bacterial export proteins, family 3 MAG.T2.48_01460 1142394.PSMK_23520 1.1e-73 283.5 Planctomycetes fliP ko:K02419,ko:K03226 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2IXMG@203682,COG1338@1,COG1338@2 NA|NA|NA N Plays a role in the flagellum-specific transport system MAG.T2.48_01462 1142394.PSMK_23540 4.8e-24 117.9 Planctomycetes fliN ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 2J00Z@203682,COG1886@1,COG1886@2 NA|NA|NA N Flagellar motor switch type III secretory pathway MAG.T2.48_01464 344747.PM8797T_10589 3.9e-17 95.9 Planctomycetes Bacteria 2IZX6@203682,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase MAG.T2.48_01465 1142394.PSMK_25110 3.1e-47 196.1 Bacteria bamD ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria COG4105@1,COG4105@2 NA|NA|NA S cell envelope organization MAG.T2.48_01466 1142394.PSMK_25100 5.8e-20 104.4 Planctomycetes lptE GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 ko:K03643 ko00000,ko02000 1.B.42.1 iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 Bacteria 2J0MT@203682,COG2980@1,COG2980@2 NA|NA|NA M Lipopolysaccharide-assembly MAG.T2.48_01467 1142394.PSMK_25340 6.4e-207 727.2 Planctomycetes ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2IWU2@203682,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins MAG.T2.48_01469 390989.JOEG01000001_gene4784 1.9e-16 92.8 Micromonosporales Bacteria 2HWUK@201174,4DKDX@85008,COG1714@1,COG1714@2 NA|NA|NA S RDD family MAG.T2.48_01471 224911.27350915 5.4e-195 687.2 Bradyrhizobiaceae Bacteria 1MWTW@1224,2TUR1@28211,3JWWF@41294,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T2.48_01472 584708.Apau_2375 5.4e-07 60.8 Bacteria Bacteria COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity MAG.T2.48_01475 1173020.Cha6605_0843 6.4e-74 283.5 Cyanobacteria 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 1G38J@1117,COG3865@1,COG3865@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase MAG.T2.48_01477 886293.Sinac_4133 1e-71 277.3 Planctomycetes Bacteria 2J2FF@203682,COG5649@1,COG5649@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T2.48_01478 1403819.BATR01000009_gene302 1.5e-219 768.8 Verrucomicrobiae 3.1.6.12 ko:K01135 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVET@203494,46TNU@74201,COG3119@1,COG3119@2 NA|NA|NA P Type I phosphodiesterase / nucleotide pyrophosphatase MAG.T2.48_01480 195253.Syn6312_3662 1.2e-93 349.7 Cyanobacteria 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 Bacteria 1G3BF@1117,COG4106@1,COG4106@2 NA|NA|NA S PFAM methyltransferase MAG.T2.48_01481 187272.Mlg_0420 1.2e-52 213.4 Gammaproteobacteria ubiG 2.1.1.294,2.7.1.181 ko:K18827 R10657,R10658 RC00002,RC00003,RC00078,RC03220 ko00000,ko01000,ko01005 Bacteria 1R9ZR@1224,1S27B@1236,COG2227@1,COG2227@2 NA|NA|NA H Methyl-transferase MAG.T2.48_01482 1122185.N792_08760 7.7e-164 583.6 Xanthomonadales cls ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1MWUW@1224,1S1J7@1236,1X5N3@135614,COG1502@1,COG1502@2 NA|NA|NA I Cardiolipin synthetase MAG.T2.48_01483 530564.Psta_0826 3.1e-31 141.7 Planctomycetes Bacteria 2IZPC@203682,COG3685@1,COG3685@2 NA|NA|NA S Domain of unknown function (DUF892) MAG.T2.48_01487 497964.CfE428DRAFT_6579 1.2e-64 252.7 Verrucomicrobia MA20_15105 Bacteria 46SRI@74201,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase MAG.T2.48_01488 1121015.N789_03900 5.6e-35 154.1 Xanthomonadales Bacteria 1QG4M@1224,1TDHA@1236,1XAQJ@135614,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain MAG.T2.48_01489 1121382.JQKG01000020_gene1204 8.4e-23 113.6 Bacteria 2.3.1.255 ko:K20791 ko00000,ko01000,ko03036 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.48_01490 1122603.ATVI01000009_gene2646 1.7e-234 818.5 Xanthomonadales Bacteria 1MXMP@1224,1RYZM@1236,1X44F@135614,COG1075@1,COG1075@2 NA|NA|NA S PGAP1-like protein MAG.T2.48_01491 1463917.JODC01000005_gene6463 2.1e-09 70.1 Actinobacteria Bacteria 2I90K@201174,COG4402@1,COG4402@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2330) MAG.T2.48_01492 373994.Riv7116_0184 5e-90 338.2 Nostocales pntA GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1G1D1@1117,1HJ2V@1161,COG3288@1,COG3288@2 NA|NA|NA C PFAM Alanine dehydrogenase PNT, C-terminal domain MAG.T2.48_01493 234267.Acid_3374 2.6e-19 101.7 Acidobacteria pntA-2 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 3Y5PH@57723,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch MAG.T2.48_01494 204669.Acid345_4185 6.1e-146 524.2 Acidobacteriia pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2JM1F@204432,3Y42H@57723,COG1282@1,COG1282@2 NA|NA|NA C NAD(P) transhydrogenase beta subunit MAG.T2.48_01496 644966.Tmar_0540 4.5e-26 124.4 Bacteria Bacteria COG2258@1,COG2258@2 NA|NA|NA C MOSC domain MAG.T2.48_01497 886293.Sinac_4835 1e-93 351.3 Planctomycetes wspA ko:K03406,ko:K13487 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 2IYQX@203682,COG0840@1,COG0840@2,COG4191@1,COG4191@2 NA|NA|NA NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). MAG.T2.48_01498 1430440.MGMSRv2_2014 9.1e-86 324.3 Rhodospirillales amiC1 ko:K01999,ko:K11959 ko02010,ko02024,map02010,map02024 M00237,M00323 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 Bacteria 1MU8V@1224,2JT2M@204441,2TS3I@28211,COG0683@1,COG0683@2 NA|NA|NA E Periplasmic binding protein domain MAG.T2.48_01499 1142394.PSMK_12640 6.7e-92 344.7 Planctomycetes pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2IXEX@203682,COG0508@1,COG0508@2 NA|NA|NA C TIGRFAM pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form MAG.T2.48_01500 1142394.PSMK_00250 2.6e-117 428.7 Planctomycetes pdhB 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2753 Bacteria 2IYRX@203682,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain MAG.T2.48_01501 1142394.PSMK_00290 3.1e-87 328.9 Planctomycetes pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2IXGM@203682,COG1071@1,COG1071@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T2.48_01502 1142394.PSMK_15360 9.9e-75 288.5 Planctomycetes ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 2IX9Q@203682,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.48_01504 38833.XP_003057912.1 1.8e-151 542.7 Chlorophyta ASA1 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009507,GO:0009536,GO:0009889,GO:0009987,GO:0010600,GO:0010817,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019222,GO:0019438,GO:0019752,GO:0031323,GO:0031326,GO:0032350,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046885,GO:0050789,GO:0050794,GO:0065007,GO:0065008,GO:0071704,GO:0090354,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Viridiplantae 34GT5@3041,37PW6@33090,COG0147@1,KOG1223@2759 NA|NA|NA E Anthranilate synthase component I, N terminal region MAG.T2.48_01505 1142394.PSMK_30320 3.8e-39 167.9 Planctomycetes ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IZJS@203682,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group MAG.T2.48_01506 595460.RRSWK_06495 1.2e-11 77.4 Planctomycetes Bacteria 2A5UW@1,2IZAT@203682,30UKM@2 NA|NA|NA MAG.T2.48_01507 1449063.JMLS01000014_gene1571 3.8e-31 142.1 Paenibacillaceae 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1UZVB@1239,26SS1@186822,4H9SV@91061,COG0720@1,COG0720@2 NA|NA|NA H 6-pyruvoyl tetrahydropterin synthase MAG.T2.48_01508 1142394.PSMK_09530 1.5e-12 79.0 Bacteria Bacteria COG3369@1,COG3369@2 NA|NA|NA I Iron-binding zinc finger CDGSH type MAG.T2.48_01509 1142394.PSMK_27450 9.7e-32 143.3 Planctomycetes Bacteria 2IZK3@203682,COG4747@1,COG4747@2 NA|NA|NA S COG4747 ACT domain-containing protein MAG.T2.48_01510 344747.PM8797T_12568 9.6e-63 247.3 Planctomycetes mqnD ko:K07083,ko:K11785 ko00130,ko01110,map00130,map01110 R08589 RC02330 ko00000,ko00001,ko01000 Bacteria 2IXIY@203682,COG2107@1,COG2107@2 NA|NA|NA S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.48_01511 1384054.N790_08345 1.7e-127 463.4 Xanthomonadales 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUBX@1224,1RMT7@1236,1X4HY@135614,COG4805@1,COG4805@2 NA|NA|NA S protein conserved in bacteria MAG.T2.48_01513 1142394.PSMK_28950 2.7e-40 172.2 Planctomycetes blaB4 1.1.1.306,3.1.2.6 ko:K00153,ko:K01069 ko00620,map00620 R01736,R09129,R10301 RC00004,RC00069,RC00137,RC01715 ko00000,ko00001,ko01000 Bacteria 2IZHE@203682,COG0491@1,COG0491@2 NA|NA|NA P COG0491 Zn-dependent hydrolases, including glyoxylases MAG.T2.48_01515 1142394.PSMK_03310 1.8e-71 276.9 Planctomycetes norM ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2IXGS@203682,COG0534@1,COG0534@2 NA|NA|NA V MatE MAG.T2.48_01516 1142394.PSMK_14850 1.2e-130 473.4 Planctomycetes mqnC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX1I@203682,COG1060@1,COG1060@2 NA|NA|NA H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.48_01517 575540.Isop_2276 1.4e-100 374.0 Planctomycetes ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2IXK4@203682,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T2.48_01518 1142394.PSMK_20090 1.6e-104 386.3 Planctomycetes rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2IXW1@203682,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T2.48_01519 1220583.GOACH_04_04370 2.1e-10 72.8 Gordoniaceae Bacteria 2E37T@1,2IIXC@201174,32Y7G@2,4GEIZ@85026 NA|NA|NA S Protein of unknown function (DUF2752) MAG.T2.48_01521 1122971.BAME01000098_gene5796 2e-08 65.9 Bacteria Bacteria COG4640@1,COG4640@2 NA|NA|NA KT response to antibiotic MAG.T2.48_01522 478741.JAFS01000001_gene1391 3.5e-46 194.1 unclassified Verrucomicrobia iorA 1.2.7.11,1.2.7.3,1.2.7.8 ko:K00175,ko:K04090 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 37FUX@326457,46VFZ@74201,COG1014@1,COG1014@2,COG4231@1,COG4231@2 NA|NA|NA C Pyruvate ferredoxin/flavodoxin oxidoreductase MAG.T2.48_01523 1142394.PSMK_07400 9.4e-28 131.0 Planctomycetes yidA Bacteria 2J0VT@203682,COG0561@1,COG0561@2 NA|NA|NA S TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily MAG.T2.48_01525 55529.EKX55295 4.8e-83 315.1 Eukaryota Eukaryota COG0564@1,KOG1919@2759 NA|NA|NA J pseudouridine synthase activity MAG.T2.48_01526 518766.Rmar_2335 1.7e-44 186.0 Bacteroidetes Order II. Incertae sedis aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 ko:K00684 R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 Bacteria 1FJ9V@1100069,4NG3A@976,COG2360@1,COG2360@2 NA|NA|NA O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine MAG.T2.48_01527 1142394.PSMK_10830 6.9e-80 304.3 Planctomycetes sbtA ko:K07086 ko00000 Bacteria 2IXB4@203682,COG3329@1,COG3329@2 NA|NA|NA S Na+-dependent bicarbonate transporter superfamily MAG.T2.48_01528 1123517.JOMR01000001_gene1663 2e-09 68.6 Bacteria ko:K04752 ko00000 Bacteria COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family MAG.T2.48_01529 247490.KSU1_C1442 2.7e-243 847.8 Planctomycetes Bacteria 2IXNZ@203682,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase MAG.T2.48_01530 1121035.AUCH01000004_gene368 1.6e-73 283.1 Rhodocyclales Bacteria 1PRWK@1224,2KZF1@206389,2WA1G@28216,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase MAG.T2.48_01533 314230.DSM3645_18466 3.4e-114 418.3 Planctomycetes yfcH ko:K07071 ko00000 Bacteria 2IYWK@203682,COG1090@1,COG1090@2 NA|NA|NA S nucleoside-diphosphate sugar epimerase MAG.T2.48_01537 502025.Hoch_2695 1.4e-129 469.9 Proteobacteria 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79,1.2.99.10 ko:K00128,ko:K00135,ko:K22445 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 1R5Y2@1224,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.48_01538 1177594.MIC448_670007 2.1e-32 146.0 Actinobacteria 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP7A@201174,COG4122@1,COG4122@2 NA|NA|NA L o-methyltransferase MAG.T2.48_01541 1254432.SCE1572_25285 2.1e-23 115.5 Bacteria Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.48_01543 87626.PTD2_06120 6.2e-54 217.6 Pseudoalteromonadaceae cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1NGFN@1224,1S237@1236,2Q4HY@267888,COG0288@1,COG0288@2 NA|NA|NA P Carbonic anhydrase MAG.T2.48_01545 1210884.HG799466_gene12573 2.2e-110 405.2 Planctomycetes sdhB1 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0247c Bacteria 2J136@203682,COG0479@1,COG0479@2 NA|NA|NA C 2Fe-2S iron-sulfur cluster binding domain MAG.T2.48_01546 204669.Acid345_1384 6.2e-260 903.3 Acidobacteriia sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2JKAD@204432,3Y6IU@57723,COG1053@1,COG1053@2 NA|NA|NA C Fumarate reductase flavoprotein C-term MAG.T2.48_01547 1210884.HG799466_gene12570 1.2e-80 306.6 Bacteria Bacteria 2CEY7@1,2Z8CG@2 NA|NA|NA S membrane MAG.T2.48_01548 497964.CfE428DRAFT_5240 1.4e-106 392.9 Verrucomicrobia Bacteria 46SAH@74201,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T2.48_01550 1142394.PSMK_26330 4e-59 235.0 Planctomycetes glmU GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 Bacteria 2IXXB@203682,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain MAG.T2.48_01551 1142394.PSMK_26340 9.2e-109 400.2 Planctomycetes prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 2IXI0@203682,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) MAG.T2.48_01552 1142394.PSMK_26350 1.4e-31 143.3 Planctomycetes ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2J050@203682,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance MAG.T2.48_01553 575540.Isop_2892 2.6e-45 188.7 Planctomycetes pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2IZXT@203682,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis MAG.T2.48_01554 237368.SCABRO_01906 2.6e-12 78.6 Bacteria rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA MAG.T2.48_01555 583355.Caka_1586 2.6e-34 151.8 Opitutae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 3K80H@414999,46VZR@74201,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein MAG.T2.48_01556 1142394.PSMK_16160 3.5e-33 148.7 Planctomycetes rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZCC@203682,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA MAG.T2.48_01557 1142394.PSMK_17450 9.9e-38 163.3 Planctomycetes nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IX3H@203682,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen MAG.T2.48_01558 1142394.PSMK_23320 1.5e-264 919.5 Planctomycetes mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 GT51 Bacteria 2IWV4@203682,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site MAG.T2.48_01559 383372.Rcas_1691 1.7e-12 79.0 Chloroflexia comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2G771@200795,377EV@32061,COG1555@1,COG1555@2 NA|NA|NA L TIGRFAM competence protein ComEA helix-hairpin-helix repeat protein MAG.T2.48_01560 1142394.PSMK_21970 1.3e-72 280.8 Planctomycetes Bacteria 2IXI6@203682,COG3693@1,COG3693@2 NA|NA|NA G PFAM glycoside hydrolase, family 10 MAG.T2.48_01561 1210884.HG799466_gene12756 3.1e-85 322.0 Planctomycetes purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2IY7D@203682,COG0152@1,COG0152@2 NA|NA|NA F SAICAR synthetase MAG.T2.48_01562 717785.HYPMC_4499 4.1e-63 248.4 Hyphomicrobiaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWU4@1224,2TRZZ@28211,3N6BF@45401,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate MAG.T2.48_01563 1123242.JH636435_gene2585 1.8e-50 206.8 Planctomycetes ko:K03671,ko:K07152 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03029,ko03110 Bacteria 2J06Z@203682,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.48_01565 1122915.AUGY01000040_gene575 2e-54 219.9 Paenibacillaceae Bacteria 1TQ72@1239,26ST6@186822,4HAGN@91061,COG0673@1,COG0673@2 NA|NA|NA K Oxidoreductase MAG.T2.48_01566 518766.Rmar_0499 5.4e-44 185.3 Bacteroidetes dadA 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 4NEUE@976,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase MAG.T2.48_01568 661478.OP10G_0856 2.1e-145 523.1 Bacteria yuxL 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T2.48_01569 1485545.JQLW01000008_gene1918 4e-68 264.6 Proteobacteria folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY3N@1224,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase MAG.T2.48_01570 28115.HR11_04060 1.4e-49 204.1 Porphyromonadaceae Bacteria 22XI6@171551,2FPY9@200643,4NJJR@976,COG4099@1,COG4099@2 NA|NA|NA S phospholipase Carboxylesterase MAG.T2.48_01572 765952.PUV_06410 1.8e-196 692.2 Bacteria glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria COG0423@1,COG0423@2 NA|NA|NA J glycyl-tRNA aminoacylation MAG.T2.48_01573 483219.LILAB_20790 4.6e-68 264.6 Bacteria ko:K09166 ko00000 Bacteria COG3361@1,COG3361@2 NA|NA|NA S conserved protein (COG2071) MAG.T2.48_01574 570268.ANBB01000013_gene3049 5.2e-13 82.4 Streptosporangiales Bacteria 2I90K@201174,4EP6S@85012,COG4402@1,COG4402@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2330) MAG.T2.48_01575 1142394.PSMK_25540 1.8e-47 196.1 Planctomycetes trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2IZJM@203682,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA MAG.T2.48_01576 1449049.JONW01000008_gene539 2.1e-75 290.4 Caulobacterales ko:K06889 ko00000 Bacteria 1R67P@1224,2KFDQ@204458,2U3D5@28211,COG1073@1,COG1073@2 NA|NA|NA S X-Pro dipeptidyl-peptidase (S15 family) MAG.T2.48_01577 1145276.T479_07635 1.8e-28 132.1 Lysinibacillus panD GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0010467,GO:0015939,GO:0015940,GO:0016053,GO:0016485,GO:0016540,GO:0016829,GO:0016830,GO:0016831,GO:0019538,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_0139,iYL1228.KPN_00139 Bacteria 1V6NQ@1239,3IY3Q@400634,4HIV1@91061,COG0853@1,COG0853@2 NA|NA|NA H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine MAG.T2.48_01578 1142394.PSMK_02820 1.1e-23 116.3 Planctomycetes rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 2J0AM@203682,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation MAG.T2.48_01579 575540.Isop_0679 2.5e-07 61.6 Planctomycetes rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J1A6@203682,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family MAG.T2.48_01581 518766.Rmar_0186 6.5e-58 230.7 Bacteroidetes Order II. Incertae sedis pdxH GO:0000166,GO:0003674,GO:0003824,GO:0004733,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016638,GO:0016641,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019842,GO:0032553,GO:0032991,GO:0034641,GO:0036094,GO:0042301,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902444 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 iJN678.pdxH,iNJ661.Rv2607 Bacteria 1FJ7D@1100069,4NFH7@976,COG0259@1,COG0259@2 NA|NA|NA H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) MAG.T2.48_01582 1142394.PSMK_24270 0.0 1266.1 Planctomycetes dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IYGA@203682,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III alpha subunit MAG.T2.48_01583 1142394.PSMK_19370 9.1e-55 220.7 Planctomycetes 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IY3N@203682,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family MAG.T2.48_01584 1142394.PSMK_18220 6.9e-143 514.6 Planctomycetes ko:K06158 ko00000,ko03012 Bacteria 2IX59@203682,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T2.48_01586 1051632.TPY_1932 1e-24 120.2 Firmicutes ko:K03088 ko00000,ko03021 Bacteria 1V8QX@1239,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.48_01587 794903.OPIT5_25660 2e-08 66.6 Opitutae Bacteria 3K9MA@414999,46VVB@74201,COG4968@1,COG4968@2 NA|NA|NA NU Prepilin-type N-terminal cleavage methylation domain MAG.T2.48_01588 1142394.PSMK_12310 3.2e-238 831.2 Planctomycetes dnaK ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2IWWS@203682,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein MAG.T2.48_01590 290397.Adeh_0155 2.7e-63 249.2 Myxococcales Bacteria 1NFSV@1224,2WP9X@28221,2YVJF@29,42SU3@68525,COG0500@1,COG0640@1,COG0640@2,COG2226@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T2.48_01594 497964.CfE428DRAFT_3494 3e-16 92.4 Bacteria omcN ko:K08999 ko00000 Bacteria COG3880@1,COG3880@2 NA|NA|NA E PFAM UvrB UvrC protein MAG.T2.48_01595 1142394.PSMK_21860 1e-80 307.0 Planctomycetes ko:K03086 ko00000,ko03021 Bacteria 2IYCB@203682,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T2.48_01596 1142394.PSMK_21250 5e-114 417.9 Planctomycetes gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 iSFV_1184.SFV_2953 Bacteria 2IWRE@203682,COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T2.48_01597 1125863.JAFN01000001_gene3410 1.6e-29 137.1 Deltaproteobacteria lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MUX6@1224,2WJJY@28221,42M4X@68525,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.48_01598 1142394.PSMK_07170 1.5e-147 530.4 Planctomycetes yaeT ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 2IWWA@203682,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein assembly complex, YaeT protein MAG.T2.48_01601 906888.JCM19314_1428 1.2e-37 164.1 Nonlabens lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1HXDW@117743,3HKYC@363408,4NH6I@976,COG1044@1,COG1044@2 NA|NA|NA I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.48_01602 1142394.PSMK_05870 2.3e-118 432.6 Planctomycetes lpxC GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 iECS88_1305.ECS88_0100 Bacteria 2IZ4S@203682,COG0764@1,COG0764@2,COG0774@1,COG0774@2 NA|NA|NA M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis MAG.T2.48_01603 1000565.METUNv1_01288 9.6e-49 200.7 Rhodocyclales lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 iIT341.HP1375 Bacteria 1MUHQ@1224,2KV6X@206389,2VHDG@28216,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.48_01606 1429851.X548_02915 1.5e-68 267.3 Xanthomonadales 2.1.1.72 ko:K07317 ko00000,ko01000,ko02048 Bacteria 1NPZV@1224,1TKDZ@1236,1XBSU@135614,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase MAG.T2.48_01607 67281.JNZZ01000026_gene4961 1.1e-15 91.3 Actinobacteria Bacteria 2H1ND@201174,COG3886@1,COG3886@2 NA|NA|NA L PLD-like domain MAG.T2.48_01608 525903.Taci_1503 1e-39 169.9 Bacteria Bacteria COG3547@1,COG3547@2 NA|NA|NA L Transposase (IS116 IS110 IS902 family) MAG.T2.48_01609 575540.Isop_2455 7.3e-140 504.2 Planctomycetes ko:K06400 ko00000 Bacteria 2IYJH@203682,COG1961@1,COG1961@2 NA|NA|NA L Site-specific recombinase, DNA invertase Pin MAG.T2.48_01610 575540.Isop_2456 2.4e-23 115.2 Planctomycetes Bacteria 2CJ67@1,2J0JF@203682,32WT5@2 NA|NA|NA MAG.T2.48_01611 1121439.dsat_0106 5.6e-34 152.1 Desulfovibrionales Bacteria 1PZM0@1224,2CDJ3@1,2MCXK@213115,2WMMY@28221,2Z7R6@2,42P6U@68525 NA|NA|NA MAG.T2.48_01614 909663.KI867149_gene3240 7.7e-12 76.6 Syntrophobacterales Bacteria 1RFD6@1224,29Y17@1,2MS7G@213462,2WNKP@28221,30JU5@2,42RYM@68525 NA|NA|NA MAG.T2.48_01615 644282.Deba_1835 3.1e-83 315.5 Deltaproteobacteria ko:K07465 ko00000 Bacteria 1R7M6@1224,2WK4C@28221,42N2C@68525,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily MAG.T2.48_01616 552811.Dehly_1693 9.2e-72 276.9 Bacteria Bacteria COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily MAG.T2.48_01618 234267.Acid_1288 9.4e-76 291.2 Acidobacteria pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 3Y33T@57723,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T2.48_01621 1123508.JH636440_gene2232 3.7e-38 164.9 Planctomycetes rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1604 Bacteria 2IZKI@203682,COG0698@1,COG0698@2 NA|NA|NA G COG0698 Ribose 5-phosphate isomerase RpiB MAG.T2.48_01622 1122207.MUS1_01235 1.5e-20 106.3 Bacteria 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 ko:K01104,ko:K01808,ko:K07566,ko:K20201 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030,R10463 RC00376,RC00434,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 Bacteria COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MAG.T2.48_01625 1142394.PSMK_03840 2.5e-92 345.9 Planctomycetes dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IY9S@203682,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria MAG.T2.48_01626 517418.Ctha_0234 2.6e-31 142.5 Chlorobi Bacteria 1FF4E@1090,COG1225@1,COG1225@2 NA|NA|NA O Redoxin MAG.T2.48_01627 426117.M446_6628 4.4e-20 105.5 Methylobacteriaceae dsbD 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 1JSKK@119045,1MU8W@1224,2TTUM@28211,COG4232@1,COG4232@2,COG4233@1,COG4233@2 NA|NA|NA CO Disulphide bond corrector protein DsbC MAG.T2.48_01629 1123508.JH636439_gene883 1.1e-57 230.3 Planctomycetes atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2IXDI@203682,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex MAG.T2.48_01630 1142394.PSMK_11890 2e-60 239.6 Planctomycetes phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 2IXEB@203682,COG1235@1,COG1235@2 NA|NA|NA S of the beta-lactamase superfamily I MAG.T2.48_01631 1142394.PSMK_18860 3.2e-59 235.7 Planctomycetes thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iJN678.thiE,iNJ661.Rv0414c Bacteria 2IY16@203682,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) MAG.T2.48_01632 379066.GAU_2048 5.2e-70 271.2 Gemmatimonadetes sodB 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 1ZT7S@142182,COG0605@1,COG0605@2 NA|NA|NA C Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T2.48_01633 1144275.COCOR_00369 1.3e-19 103.2 Myxococcales Bacteria 1NFEJ@1224,2X77S@28221,2YVY8@29,43BX0@68525,COG3386@1,COG3386@2 NA|NA|NA G PFAM SMP-30 Gluconolaconase MAG.T2.48_01634 861299.J421_4478 1.9e-61 243.4 Gemmatimonadetes Bacteria 1ZU9S@142182,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T2.48_01635 373994.Riv7116_4574 1.9e-25 122.9 Nostocales Bacteria 1G69P@1117,1HN1T@1161,COG1994@1,COG1994@2 NA|NA|NA S Peptidase family M50 MAG.T2.48_01636 1121957.ATVL01000014_gene1459 4.6e-84 319.7 Cytophagia Bacteria 47VHU@768503,4PHUI@976,COG5563@1,COG5563@2 NA|NA|NA MAG.T2.48_01637 595460.RRSWK_05002 2.7e-17 94.7 Planctomycetes rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2J0X7@203682,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family MAG.T2.48_01638 1123405.AUMM01000002_gene327 1.9e-66 259.2 Sporolactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,26NJH@186821,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J tRNA (Guanine-1)-methyltransferase MAG.T2.48_01639 1142394.PSMK_12470 5.2e-31 141.0 Planctomycetes rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZVX@203682,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site MAG.T2.48_01641 1385515.N791_08360 1.7e-36 158.7 Xanthomonadales queD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324 Bacteria 1RI4P@1224,1S3T6@1236,1X6I0@135614,COG0720@1,COG0720@2 NA|NA|NA H synthase MAG.T2.48_01642 521674.Plim_0125 9.7e-22 110.2 Planctomycetes Bacteria 2J0AU@203682,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T2.48_01643 314230.DSM3645_06149 3.2e-43 181.8 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2J0GI@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.48_01645 497964.CfE428DRAFT_2969 5.3e-86 325.1 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity MAG.T2.48_01646 1142394.PSMK_07140 2.8e-66 258.5 Planctomycetes Bacteria 2IXXW@203682,COG1403@1,COG1403@2 NA|NA|NA L PFAM HNH endonuclease MAG.T2.48_01647 1121428.DESHY_70053___1 2.5e-09 70.5 Peptococcaceae ko:K07052 ko00000 Bacteria 1V1GB@1239,25CF3@186801,2676H@186807,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T2.48_01648 446468.Ndas_5158 1.8e-39 169.1 Streptosporangiales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFG1@201174,4EIMC@85012,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly MAG.T2.48_01649 756272.Plabr_3639 2.7e-28 131.7 Planctomycetes rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J01J@203682,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family MAG.T2.48_01651 1142394.PSMK_13500 6.3e-43 181.4 Planctomycetes mqnA 1.21.98.1,4.2.1.151 ko:K07081,ko:K11782,ko:K11784 ko00130,ko01110,map00130,map01110 R08588,R10666 RC02329,RC03232 ko00000,ko00001,ko01000 Bacteria 2IYUW@203682,COG1427@1,COG1427@2 NA|NA|NA H Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.48_01652 180281.CPCC7001_1720 4.5e-56 225.3 Cyanobium bcsA Bacteria 1G098@1117,22TGN@167375,COG3424@1,COG3424@2 NA|NA|NA Q Chalcone and stilbene synthases, C-terminal domain MAG.T2.48_01653 69042.WH5701_04045 5.3e-18 99.0 Synechococcus fixC 1.3.99.38 ko:K21401 ko00000,ko01000 Bacteria 1GCGZ@1117,1GZ32@1129,COG0644@1,COG0644@2 NA|NA|NA C NAD binding site MAG.T2.48_01654 1142394.PSMK_09540 2e-63 250.0 Planctomycetes alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 2IZJH@203682,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids MAG.T2.48_01655 575540.Isop_1517 1.8e-89 336.7 Planctomycetes deaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2IX02@203682,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation MAG.T2.48_01656 1432056.X781_70 4.5e-50 205.3 Pasteurellales psuG GO:0001522,GO:0003674,GO:0003824,GO:0004730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016787,GO:0016798,GO:0016829,GO:0016835,GO:0016836,GO:0019200,GO:0022607,GO:0030145,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0090304,GO:1901360 4.2.1.70 ko:K16329 ko00240,map00240 R01055 RC00432,RC00433 ko00000,ko00001,ko01000 Bacteria 1MUQU@1224,1RQJH@1236,1Y9SC@135625,COG2313@1,COG2313@2 NA|NA|NA G Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway MAG.T2.48_01657 595460.RRSWK_00323 9e-92 344.0 Planctomycetes rho ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2IXBX@203682,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T2.48_01660 1549858.MC45_16805 1.7e-30 140.2 Sphingomonadales spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1QQ53@1224,2K2P3@204457,2TVH5@28211,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family MAG.T2.48_01661 1142394.PSMK_28350 4e-134 485.0 Planctomycetes murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2IWRI@203682,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine MAG.T2.48_01662 1121930.AQXG01000002_gene2065 3.3e-66 258.8 Bacteria petH GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464 1.14.13.208,1.18.1.2,1.19.1.1 ko:K00528,ko:K02287,ko:K02641,ko:K15511 ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100 R09555,R10159 RC01739 ko00000,ko00001,ko00194,ko01000 iJN678.petH Bacteria COG0369@1,COG0369@2 NA|NA|NA C hydroxylamine reductase activity MAG.T2.48_01663 867903.ThesuDRAFT_01213 2.2e-133 482.6 Clostridiales incertae sedis fumC 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,25F3I@186801,3WCCI@538999,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T2.48_01666 1142394.PSMK_18400 7.9e-11 72.8 Planctomycetes rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J05Y@203682,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit MAG.T2.48_01667 1142394.PSMK_12520 6.8e-41 176.0 Bacteria gcvT 1.5.99.5,2.1.2.10 ko:K00605,ko:K06980,ko:K22086 ko00260,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200 M00532 R00609,R01221,R02300,R04125 RC00022,RC00069,RC00183,RC00190,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T2.48_01669 1123247.AUIJ01000001_gene1434 2.2e-77 295.8 Alphaproteobacteria mvaB GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUMX@1224,2TT1R@28211,COG0119@1,COG0119@2 NA|NA|NA E hydroxy-methylglutaryl-CoA lyase MAG.T2.48_01670 1142394.PSMK_18790 3.4e-33 149.1 Bacteria 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria COG2908@1,COG2908@2 NA|NA|NA M Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.48_01672 1142394.PSMK_18470 1.4e-144 520.0 Planctomycetes miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2IX1E@203682,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine MAG.T2.48_01673 1142394.PSMK_07960 8e-60 238.0 Planctomycetes ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2IZT9@203682,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T2.48_01674 1142394.PSMK_07970 1.3e-56 227.3 Planctomycetes murG GO:0008150,GO:0040007 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2J057@203682,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) MAG.T2.48_01676 1396141.BATP01000027_gene1057 3.9e-20 106.7 Bacteria Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T2.48_01679 335543.Sfum_2449 7.3e-73 280.8 Syntrophobacterales mlaF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MUSD@1224,2MQE7@213462,2WKRT@28221,42NI4@68525,COG1127@1,COG1127@2 NA|NA|NA Q PFAM ABC transporter MAG.T2.48_01680 247490.KSU1_C0507 5.7e-72 278.5 Planctomycetes omcB Bacteria 2IY9X@203682,COG1361@1,COG1361@2 NA|NA|NA M 60 kDa outer membrane protein MAG.T2.48_01681 1142394.PSMK_14660 4.1e-67 262.3 Planctomycetes murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2IX53@203682,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) MAG.T2.48_01683 45157.CMT435CT 8.1e-45 186.8 Eukaryota MCS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0015994,GO:0015995,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 iRC1080.CRv4_Au5_s12_g3144_t1 Eukaryota 2QS77@2759,COG0245@1 NA|NA|NA I 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity MAG.T2.48_01684 1142394.PSMK_11820 2.1e-144 518.8 Bacteria 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria COG2019@1,COG2019@2 NA|NA|NA F adenylate kinase activity MAG.T2.48_01686 1192034.CAP_3572 1.9e-193 682.6 Myxococcales 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 1MVM7@1224,2X27Z@28221,2YWM4@29,435PV@68525,COG0296@1,COG0296@2 NA|NA|NA G Domain of unknown function (DUF3459) MAG.T2.48_01687 1396141.BATP01000034_gene4137 1.9e-09 69.7 Bacteria Bacteria COG4932@1,COG4932@2 NA|NA|NA M domain protein MAG.T2.48_01688 243231.GSU0371 2.2e-163 582.8 Desulfuromonadales glgP 2.4.1.1,2.4.1.8 ko:K00688,ko:K00691 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R01555,R02111 RC00049 ko00000,ko00001,ko01000 GH65,GT35 Bacteria 1MW4J@1224,2WIPF@28221,42MEQ@68525,43T5A@69541,COG0058@1,COG0058@2 NA|NA|NA G Protein of unknown function (DUF3417) MAG.T2.48_01689 338963.Pcar_0554 8.6e-106 391.0 Desulfuromonadales malQ 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 iJN678.malQ Bacteria 1QTVJ@1224,2WK77@28221,42PZB@68525,43STY@69541,COG1640@1,COG1640@2 NA|NA|NA G PFAM glycoside hydrolase, family 77 MAG.T2.48_01690 1142394.PSMK_19040 7.1e-145 521.5 Bacteria 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 R02112,R03122,R11262 ko00000,ko00001,ko01000 GH13 Bacteria COG0366@1,COG0366@2 NA|NA|NA G hydrolase activity, hydrolyzing O-glycosyl compounds MAG.T2.48_01691 661478.OP10G_1366 6.2e-82 312.4 Bacteria ko:K02025,ko:K02027,ko:K10201,ko:K15771 ko02010,map02010 M00205,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2 Bacteria COG1175@1,COG1175@2,COG1653@1,COG1653@2 NA|NA|NA P transmembrane transport MAG.T2.48_01692 452637.Oter_1750 3.9e-56 225.3 Opitutae ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 3K8AG@414999,46TIW@74201,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component MAG.T2.48_01693 880073.Calab_3484 1.6e-91 343.2 unclassified Bacteria msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 2NNU0@2323,COG3842@1,COG3842@2 NA|NA|NA E ATPases associated with a variety of cellular activities MAG.T2.48_01695 1408321.JNJD01000007_gene277 2e-45 189.5 unclassified Lachnospiraceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,248W2@186801,27IG7@186928,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T2.48_01697 1142394.PSMK_30190 3.5e-61 241.9 Planctomycetes bshB1 ko:K01463 ko00000,ko01000 Bacteria 2IZ0B@203682,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase MAG.T2.48_01698 886293.Sinac_3294 2.4e-112 412.5 Planctomycetes degT Bacteria 2IXRE@203682,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T2.48_01699 1236501.BAJU01000001_gene263 5.4e-40 170.6 Rhodospirillales dut GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0865,iYO844.BSU17660 Bacteria 1RA7P@1224,2JS8T@204441,2U7B5@28211,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA MAG.T2.48_01700 867903.ThesuDRAFT_01077 1e-84 320.5 Clostridiales incertae sedis oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,247NN@186801,3WCYH@538999,COG0444@1,COG0444@2 NA|NA|NA EP Belongs to the ABC transporter superfamily MAG.T2.48_01701 1123400.KB904759_gene2063 4.4e-66 259.2 Thiotrichales appC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MU26@1224,1RND6@1236,463N1@72273,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component MAG.T2.48_01702 1142394.PSMK_25080 3.4e-73 282.7 Planctomycetes oppB ko:K02033,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 2IYGR@203682,COG0601@1,COG0601@2 NA|NA|NA P transport systems MAG.T2.48_01703 713586.KB900536_gene2999 2.4e-92 346.7 Chromatiales oppA_5 ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 1MUZH@1224,1SZ84@1236,1WXUW@135613,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle MAG.T2.48_01704 1142394.PSMK_07270 7.7e-62 244.2 Planctomycetes oppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021 Bacteria 2IYF0@203682,COG1173@1,COG1173@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component MAG.T2.48_01708 1142394.PSMK_24820 3.2e-29 135.2 Planctomycetes adsA ko:K03088 ko00000,ko03021 Bacteria 2J17G@203682,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.48_01709 1142394.PSMK_13120 1.2e-123 450.3 Planctomycetes dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2IXJT@203682,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T2.48_01710 247490.KSU1_B0124 6.3e-19 100.1 Planctomycetes ko:K03530,ko:K05788 ko00000,ko03032,ko03036,ko03400 Bacteria 2J01P@203682,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family MAG.T2.48_01712 1142394.PSMK_02310 4.3e-121 441.8 Planctomycetes hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272,ko:K21345 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_0922 Bacteria 2IY6V@203682,COG0615@1,COG0615@2,COG2870@1,COG2870@2 NA|NA|NA H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose MAG.T2.48_01713 1142394.PSMK_30040 6.8e-41 174.9 Planctomycetes lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 Bacteria 2IXYX@203682,COG1663@1,COG1663@2 NA|NA|NA F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) MAG.T2.48_01714 595460.RRSWK_04332 5.1e-20 104.8 Planctomycetes maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 ko:K03215,ko:K06287 ko00000,ko01000,ko03009 Bacteria 2IZJC@203682,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T2.48_01715 1142394.PSMK_14280 8.4e-61 241.1 Planctomycetes ko:K02841,ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 2IYZS@203682,COG0859@1,COG0859@2 NA|NA|NA M COG0859 ADP-heptose LPS heptosyltransferase MAG.T2.48_01716 1142394.PSMK_24340 2.4e-101 375.9 Planctomycetes Bacteria 2IYFB@203682,COG0515@1,COG0515@2 NA|NA|NA KLT PFAM Protein kinase domain MAG.T2.48_01718 1051632.TPY_1561 8.6e-36 156.8 Clostridia Bacteria 1V6G4@1239,24IS7@186801,COG0251@1,COG0251@2 NA|NA|NA J translation initiation inhibitor, yjgF family MAG.T2.48_01719 1142394.PSMK_17880 3.6e-12 79.3 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.48_01720 1142394.PSMK_17880 4.2e-13 82.4 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.48_01721 1142394.PSMK_08030 4.8e-50 206.1 Planctomycetes ko:K07403 ko00000 Bacteria 2IWTY@203682,COG1030@1,COG1030@2 NA|NA|NA O ClpP class MAG.T2.48_01722 1142394.PSMK_30750 4.7e-17 94.7 Planctomycetes yqeZ ko:K07403 ko00000 Bacteria 2J0K3@203682,COG1030@1,COG1030@2 NA|NA|NA O Membrane-bound serine protease (ClpP class) MAG.T2.48_01723 886293.Sinac_1416 2.6e-90 339.0 Planctomycetes yqfA Bacteria 2IXDK@203682,COG4864@1,COG4864@2 NA|NA|NA S UPF0365 protein MAG.T2.48_01724 644968.DFW101_1816 8.9e-41 174.1 Desulfovibrionales Bacteria 1QU2F@1224,2M9BR@213115,2WKJA@28221,42P7H@68525,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.48_01726 521674.Plim_3505 8.3e-36 158.3 Planctomycetes ko:K18475 ko00000,ko01000,ko02035 Bacteria 2DX1R@1,2J54M@203682,34301@2 NA|NA|NA MAG.T2.48_01727 401526.TcarDRAFT_1170 6.7e-45 187.6 Negativicutes rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_1875,iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Bacteria 1V6RN@1239,4H4DD@909932,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions MAG.T2.48_01728 886293.Sinac_6119 5.3e-173 614.4 Planctomycetes accD5 Bacteria 2IY0Q@203682,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) MAG.T2.48_01729 586416.GZ22_07090 1.8e-21 108.2 Bacilli rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome MAG.T2.48_01730 756272.Plabr_4488 2.5e-191 675.6 Planctomycetes pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2IWXZ@203682,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction MAG.T2.48_01731 1089553.Tph_c24870 7e-13 79.7 Clostridia cspA ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,24QJE@186801,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein MAG.T2.48_01732 1142394.PSMK_05310 1.4e-48 200.3 Bacteria Bacteria COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T2.48_01733 215803.DB30_3357 4.1e-66 258.1 Proteobacteria pepE GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.11.2,3.4.13.21 ko:K01256,ko:K05995 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1N29W@1224,COG3340@1,COG3340@2 NA|NA|NA E Belongs to the peptidase S51 family MAG.T2.48_01734 530564.Psta_0958 2.1e-128 465.7 Planctomycetes top6A 5.99.1.3 ko:K03166 ko00000,ko01000,ko03032 Bacteria 2J34C@203682,COG1697@1,COG1697@2 NA|NA|NA L Relaxes both positive and negative superturns and exhibits a strong decatenase activity MAG.T2.48_01735 330214.NIDE2073 1.2e-140 507.3 Bacteria top6B 5.99.1.3 ko:K03167 ko00000,ko01000,ko03032 Bacteria COG1389@1,COG1389@2 NA|NA|NA L DNA topoisomerase II activity MAG.T2.48_01736 247490.KSU1_D0284 6.5e-44 183.7 Planctomycetes ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 2IZQ6@203682,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate MAG.T2.48_01737 1142394.PSMK_11590 9.8e-69 267.3 Planctomycetes ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 2IY72@203682,COG0568@1,COG0568@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.48_01738 243230.DR_A0068 1.7e-96 359.0 Deinococcus-Thermus scoA 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 1WM5K@1297,COG1788@1,COG1788@2 NA|NA|NA I Belongs to the 3-oxoacid CoA-transferase family MAG.T2.48_01740 1142394.PSMK_23890 3.7e-126 458.8 Planctomycetes xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXGK@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.48_01741 1125863.JAFN01000001_gene2968 6e-60 238.4 Deltaproteobacteria gspF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MV4U@1224,2WJE0@28221,42MH9@68525,COG1459@1,COG1459@2 NA|NA|NA U General secretion pathway protein F MAG.T2.48_01742 272630.MexAM1_META1p0038 1.4e-14 86.3 Methylobacteriaceae gspG ko:K02246,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1JXX9@119045,1RDX2@1224,2U7GY@28211,COG2165@1,COG2165@2 NA|NA|NA U Pfam:N_methyl_2 MAG.T2.48_01746 521674.Plim_3639 3.3e-27 129.8 Planctomycetes gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 ko:K02460,ko:K12286 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IXHV@203682,COG3156@1,COG3156@2 NA|NA|NA U Type II secretion system (T2SS), protein K MAG.T2.48_01750 1142394.PSMK_14030 1.8e-62 248.1 Planctomycetes ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IX4B@203682,COG1450@1,COG1450@2 NA|NA|NA NU general secretion pathway protein D MAG.T2.48_01752 1142394.PSMK_03920 9.2e-20 106.7 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process MAG.T2.48_01754 264462.Bd1010 9.5e-210 736.9 Bdellovibrionales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MUM3@1224,2MTKJ@213481,2WJG7@28221,42NN7@68525,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) MAG.T2.48_01755 644282.Deba_0423 1.6e-17 96.3 Deltaproteobacteria queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1RI4P@1224,2WQ2Z@28221,42TJ5@68525,COG0720@1,COG0720@2 NA|NA|NA H PFAM 6-pyruvoyl tetrahydropterin synthase MAG.T2.48_01756 1142394.PSMK_27380 3.5e-93 349.0 Planctomycetes glmM 5.4.2.10,5.4.2.2,5.4.2.8 ko:K01840,ko:K03431,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R02060,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXRS@203682,COG1109@1,COG1109@2 NA|NA|NA G PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain MAG.T2.48_01757 1211114.ALIP01000124_gene722 7e-08 64.3 Proteobacteria Bacteria 1NHJ1@1224,2EH3D@1,33AVD@2 NA|NA|NA S Protein of unknown function (DUF3592) MAG.T2.48_01758 1142394.PSMK_31960 3.5e-36 158.3 Planctomycetes 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2J1PQ@203682,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T2.48_01759 1142394.PSMK_07280 2.4e-80 305.8 Planctomycetes dapA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0032787,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.72,4.3.3.7 ko:K01714,ko:K03517 ko00261,ko00300,ko00760,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00760,map01100,map01110,map01120,map01130,map01230 M00016,M00115,M00525,M00526,M00527 R04292,R10147 RC01119,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812 Bacteria 2IXII@203682,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) MAG.T2.48_01760 1123487.KB892841_gene4325 1.8e-76 293.5 Rhodocyclales pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 iAF1260.b2564,iAF987.Gmet_1885,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 Bacteria 1MU9W@1224,2KV09@206389,2VHY7@28216,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate MAG.T2.48_01761 649638.Trad_0907 2.9e-110 405.6 Bacteria CP_1013 2.7.7.23,2.7.7.83 ko:K00972,ko:K11442 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00361,M00362 R00416 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria COG4284@1,COG4284@2 NA|NA|NA G Utp--glucose-1-phosphate uridylyltransferase MAG.T2.48_01762 1142394.PSMK_31510 2.1e-98 366.7 Planctomycetes recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IXVB@203682,COG0608@1,COG0608@2 NA|NA|NA L single-stranded-DNA-specific exonuclease RecJ MAG.T2.48_01763 344747.PM8797T_19602 5.2e-49 201.1 Planctomycetes adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IZRF@203682,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism MAG.T2.48_01765 1142394.PSMK_28670 6.6e-36 158.3 Bacteria mdsC 2.7.1.162,2.7.1.39 ko:K02204,ko:K13059 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771,R08962 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria COG2334@1,COG2334@2 NA|NA|NA S homoserine kinase activity MAG.T2.48_01766 1142394.PSMK_05130 3.8e-53 215.3 Planctomycetes yicC ko:K03316 ko00000 2.A.36 Bacteria 2IYZH@203682,COG1561@1,COG1561@2 NA|NA|NA S stress-induced protein MAG.T2.48_01768 290315.Clim_1670 4.9e-57 228.0 Chlorobi tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4715 Bacteria 1FDS9@1090,COG0149@1,COG0149@2 NA|NA|NA F Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) MAG.T2.48_01769 1142394.PSMK_11970 4e-245 854.7 Planctomycetes alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IX30@203682,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain MAG.T2.48_01770 1267533.KB906733_gene3359 1.6e-235 822.4 Acidobacteriia acsA 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JI3Z@204432,3Y39K@57723,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA MAG.T2.48_01774 1123371.ATXH01000013_gene1513 7.6e-37 160.6 Thermodesulfobacteria Bacteria 2GIQV@200940,COG2203@1,COG2203@2,COG2204@1,COG2204@2,COG2206@1,COG2206@2 NA|NA|NA T HD domain MAG.T2.48_01775 452637.Oter_3628 1.5e-92 346.7 Opitutae gdh 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 3K7UU@414999,46S83@74201,COG4198@1,COG4198@2 NA|NA|NA S Protein of unknown function (DUF1015) MAG.T2.48_01776 1035308.AQYY01000001_gene2783 2.2e-113 416.0 Peptococcaceae 1.1.1.399,1.1.1.95,1.17.1.9 ko:K00058,ko:K00122 ko00260,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00519,R01513 RC00031,RC02796 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,248H9@186801,260G0@186807,COG0111@1,COG0111@2 NA|NA|NA E D-isomer specific 2-hydroxyacid dehydrogenase catalytic MAG.T2.48_01777 1191523.MROS_0721 8.8e-111 407.1 Bacteria serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine MAG.T2.48_01780 530564.Psta_1744 1.6e-80 306.6 Planctomycetes ko:K02669,ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX6Y@203682,COG2805@1,COG2805@2 NA|NA|NA NU twitching motility protein MAG.T2.48_01781 309800.C498_17750 7e-43 180.6 Halobacteria araC Archaea 23RWT@183963,2XV38@28890,COG0693@1,arCOG00769@2157 NA|NA|NA S intracellular protease amidase MAG.T2.48_01782 402777.KB235903_gene2012 2.1e-90 339.3 Oscillatoriales yfbL Bacteria 1G1QW@1117,1H7N7@1150,COG2234@1,COG2234@2 NA|NA|NA S PFAM Peptidase family M28 MAG.T2.48_01783 1385935.N836_17860 1.8e-47 196.1 Oscillatoriales Bacteria 1G841@1117,1HC2N@1150,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain MAG.T2.48_01784 1158182.KB905020_gene1814 1.2e-27 129.8 Chromatiales ptpA 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1RH90@1224,1S5X6@1236,1WY50@135613,COG0394@1,COG0394@2 NA|NA|NA T low molecular weight MAG.T2.48_01785 1121378.KB899728_gene4132 4.5e-123 448.4 Deinococcus-Thermus sthA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1WI3A@1297,COG1249@1,COG1249@2 NA|NA|NA C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) MAG.T2.48_01788 756272.Plabr_3321 2.6e-57 229.6 Planctomycetes ko:K03733 ko00000,ko03036 Bacteria 2IZWA@203682,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.48_01789 521674.Plim_0989 2.8e-93 350.1 Planctomycetes traC Bacteria 2J0Z2@203682,COG0714@1,COG0714@2,COG4643@1,COG4643@2 NA|NA|NA S Protein of unknown function (DUF3987) MAG.T2.48_01793 479432.Sros_5685 7.5e-134 484.2 Streptosporangiales 1.13.12.16 ko:K00459 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000 Bacteria 2I93H@201174,4EIEF@85012,COG2070@1,COG2070@2 NA|NA|NA S 2-Nitropropane dioxygenase MAG.T2.48_01794 45157.CMM155CT 2.2e-45 189.1 Eukaryota PDX3 GO:0000166,GO:0003674,GO:0003824,GO:0004733,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0010181,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042818,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070013,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097164,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Eukaryota COG0259@1,KOG2586@2759 NA|NA|NA H pyridoxamine-phosphate oxidase activity MAG.T2.48_01795 903818.KI912268_gene2209 2.7e-12 78.2 Bacteria Bacteria COG1917@1,COG1917@2 NA|NA|NA L Cupin 2, conserved barrel domain protein MAG.T2.48_01796 240016.ABIZ01000001_gene3546 8.9e-19 100.5 Verrucomicrobiae acrA ko:K02005 ko00000 Bacteria 2IVAY@203494,46UZZ@74201,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like MAG.T2.48_01797 926550.CLDAP_07210 3.4e-23 115.9 Bacteria copM ko:K03611 ko00000,ko03110 5.A.2.1 Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T2.48_01798 518766.Rmar_2012 4.8e-248 864.0 Bacteroidetes Order II. Incertae sedis nosZ 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 Bacteria 1FIVE@1100069,4NFNE@976,COG4263@1,COG4263@2 NA|NA|NA C Nitrous oxide reductase MAG.T2.48_01799 926550.CLDAP_07160 1.1e-63 250.0 Bacteria nosL ko:K19342 ko00000 Bacteria COG4314@1,COG4314@2 NA|NA|NA C lipoprotein involved in nitrous oxide reduction MAG.T2.48_01800 926550.CLDAP_07170 5.4e-76 292.0 Bacteria nosD ko:K07218 ko00000 Bacteria COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process MAG.T2.48_01801 518766.Rmar_2015 4.3e-55 221.5 Bacteroidetes Order II. Incertae sedis ko:K01990,ko:K07218,ko:K19340 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 1FJGQ@1100069,4PER8@976,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system MAG.T2.48_01802 926550.CLDAP_07190 1.8e-53 216.5 Bacteria nosY ko:K19341 ko02010,map02010 M00762 ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 Bacteria COG1277@1,COG1277@2 NA|NA|NA MAG.T2.48_01803 309801.trd_A0190 1.6e-19 102.8 Thermomicrobia ko:K19342 ko00000 Bacteria 27ZA8@189775,2G91T@200795,COG4314@1,COG4314@2 NA|NA|NA C NosL MAG.T2.48_01804 530564.Psta_2761 1.1e-28 133.3 Planctomycetes Bacteria 2IZQA@203682,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T2.48_01805 251229.Chro_3920 6.9e-99 367.5 Cyanobacteria Bacteria 1G5KH@1117,COG3335@1,COG3335@2,COG3415@1,COG3415@2 NA|NA|NA L Winged helix-turn helix MAG.T2.48_01807 670292.JH26_03320 1.4e-22 113.6 Methylobacteriaceae ko:K07492 ko00000 Bacteria 1JW8N@119045,1REVC@1224,2U6ZB@28211,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) MAG.T2.48_01809 1120950.KB892746_gene3462 2.8e-21 110.5 Propionibacteriales Bacteria 2I9D0@201174,4DSNJ@85009,COG4447@1,COG4447@2 NA|NA|NA S cellulose binding MAG.T2.48_01811 107635.AZUO01000001_gene3329 1.8e-15 87.8 Alphaproteobacteria ko:K09858 ko00000 Bacteria 1NGS9@1224,2UJIM@28211,COG3012@1,COG3012@2 NA|NA|NA S SEC-C motif MAG.T2.48_01812 268407.PWYN_01440 2.3e-67 264.2 Paenibacillaceae DSE4 3.2.1.73 ko:K01216 ko00000,ko01000 Bacteria 1U7U3@1239,26SHU@186822,4IT1H@91061,COG2273@1,COG2273@2,COG5498@1,COG5498@2 NA|NA|NA M glycoside hydrolase family 81 MAG.T2.48_01813 395494.Galf_2697 8.6e-219 766.5 Nitrosomonadales IV02_08645 ko:K07137 ko00000 Bacteria 1MV6P@1224,2VHGJ@28216,44V1K@713636,COG2509@1,COG2509@2 NA|NA|NA S fad dependent oxidoreductase MAG.T2.48_01815 177437.HRM2_46060 6.8e-66 260.0 Proteobacteria Bacteria 1QWP7@1224,COG2885@1,COG2885@2 NA|NA|NA M chlorophyll binding MAG.T2.48_01819 234267.Acid_4971 1.6e-45 189.5 Acidobacteria Bacteria 3Y7KD@57723,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) MAG.T2.48_01820 344747.PM8797T_15686 1.2e-44 188.0 Planctomycetes Bacteria 2IZDI@203682,COG2335@1,COG2335@2 NA|NA|NA M COG2335 Secreted and surface protein containing fasciclin-like repeats MAG.T2.48_01821 595460.RRSWK_01896 6.5e-77 294.7 Planctomycetes pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 2IX8W@203682,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family MAG.T2.48_01822 443143.GM18_0728 6.8e-224 783.5 Deltaproteobacteria yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 ko00000,ko01000 Bacteria 1MU37@1224,2WJC1@28221,42MMK@68525,COG0488@1,COG0488@2 NA|NA|NA S PFAM ABC transporter related MAG.T2.48_01823 42256.RradSPS_1875 1.3e-13 82.4 Actinobacteria ko:K07075 ko00000 Bacteria 2IQTT@201174,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T2.48_01824 237368.SCABRO_02331 1.3e-15 89.0 Bacteria Bacteria COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 MAG.T2.48_01825 472759.Nhal_3601 1.1e-09 70.5 Chromatiales terC ko:K05794 ko00000 Bacteria 1MUNR@1224,1RP9Y@1236,1WWGU@135613,COG0861@1,COG0861@2 NA|NA|NA P PFAM Integral membrane protein TerC MAG.T2.48_01827 324602.Caur_3430 8.7e-47 194.9 Chloroflexi ko:K07148 ko00000 Bacteria 2G8B7@200795,COG2311@1,COG2311@2 NA|NA|NA S Protein of unknown function (DUF418) MAG.T2.48_01828 1210884.HG799464_gene10604 1.2e-20 108.6 Planctomycetes Bacteria 2A5PP@1,2J4IH@203682,30UEI@2 NA|NA|NA MAG.T2.48_01829 240292.Ava_4728 1.5e-82 313.5 Nostocales nucH 3.4.21.50,3.4.24.40 ko:K01337,ko:K01406,ko:K07004 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1GQ21@1117,1HJBD@1161,COG2374@1,COG2374@2,COG2931@1,COG2931@2,COG3591@1,COG3591@2 NA|NA|NA L Belongs to the TPP enzyme family MAG.T2.48_01830 861299.J421_6033 3.4e-40 172.2 Gemmatimonadetes ko:K06996 ko00000 Bacteria 1ZU3H@142182,COG3324@1,COG3324@2 NA|NA|NA E translation initiation factor activity MAG.T2.48_01831 332101.JIBU02000027_gene2778 6.4e-49 201.8 Clostridiaceae Bacteria 1UYV5@1239,24B0A@186801,36DRS@31979,COG0793@1,COG0793@2 NA|NA|NA M Peptidase, S41 MAG.T2.48_01832 330214.NIDE3611 1.3e-59 237.3 Bacteria yagE Bacteria COG1723@1,COG1723@2 NA|NA|NA S PFAM Uncharacterised ACR, YagE family COG1723 MAG.T2.48_01833 312153.Pnuc_1484 1.7e-45 190.7 Burkholderiaceae Bacteria 1K11H@119060,1MXPS@1224,2VKTY@28216,COG3064@1,COG3064@2 NA|NA|NA M Protein of unknown function (DUF3300) MAG.T2.48_01834 1054213.HMPREF9946_03876 9.8e-68 263.8 Rhodospirillales flgK ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZXB@1224,2JWNT@204441,2TTM8@28211,COG4786@1,COG4786@2 NA|NA|NA N Protein of unknown function (DUF2950) MAG.T2.48_01835 316274.Haur_1906 1.2e-15 90.1 Chloroflexia Bacteria 2G7D8@200795,376E5@32061,COG2128@1,COG2128@2 NA|NA|NA S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T2.48_01836 420324.KI911943_gene5274 5.1e-18 98.6 Methylobacteriaceae ko:K03088 ko00000,ko03021 Bacteria 1JV56@119045,1MX7T@1224,2U182@28211,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.48_01837 1282362.AEAC466_06660 1.7e-16 92.4 Caulobacterales 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1MZ80@1224,2KGYX@204458,2UDE8@28211,COG0599@1,COG0599@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T2.48_01838 1121861.KB899927_gene1568 1.2e-32 146.7 Rhodospirillales ygaP Bacteria 1PFDA@1224,2JUW6@204441,2UKXF@28211,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T2.48_01839 765911.Thivi_1373 1.3e-31 143.3 Chromatiales ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N7MB@1224,1TAHN@1236,1X0YJ@135613,COG1863@1,COG1863@2 NA|NA|NA P Na+/H+ ion antiporter subunit MAG.T2.48_01840 768671.ThimaDRAFT_2824 3.2e-08 64.3 Chromatiales ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N90U@1224,1SCXI@1236,1WZ9H@135613,COG2212@1,COG2212@2 NA|NA|NA P Multiple resistance and pH regulation protein F MAG.T2.48_01841 189753.AXAS01000001_gene3772 7.9e-16 89.7 Bradyrhizobiaceae ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N75I@1224,2UETR@28211,3K0FE@41294,COG1320@1,COG1320@2 NA|NA|NA P Na+/H+ antiporter subunit MAG.T2.48_01842 765911.Thivi_1376 8.4e-65 254.2 Chromatiales Bacteria 1QVK4@1224,1T2WR@1236,1X2P8@135613,COG2111@1,COG2111@2 NA|NA|NA P Domain related to MnhB subunit of Na+/H+ antiporter MAG.T2.48_01843 1038860.AXAP01000001_gene6333 2e-20 105.1 Bradyrhizobiaceae ko:K05567 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N7TX@1224,2UHUU@28211,3JZES@41294,COG1006@1,COG1006@2 NA|NA|NA P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MAG.T2.48_01844 395965.Msil_1037 1.4e-132 479.9 Beijerinckiaceae Bacteria 1MURB@1224,2TRQ2@28211,3NCZI@45404,COG0651@1,COG0651@2 NA|NA|NA CP Proton-conducting membrane transporter MAG.T2.48_01845 1502851.FG93_03099 6.5e-120 438.0 Bradyrhizobiaceae Bacteria 1N6BY@1224,2TUZY@28211,3JXRH@41294,COG0651@1,COG0651@2 NA|NA|NA CP Proton-conducting membrane transporter MAG.T2.48_01846 1117319.PSPO_18436 6.7e-39 168.3 Pseudoalteromonadaceae ttgA Bacteria 1R4JA@1224,1RPS5@1236,2PZKY@267888,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_01847 207559.Dde_0670 1.7e-265 922.5 Desulfovibrionales Bacteria 1MU48@1224,2MG2S@213115,2WJ2A@28221,42MQ0@68525,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.48_01848 118166.JH976537_gene77 1.8e-123 449.1 Oscillatoriales glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1G1IK@1117,1H7V2@1150,COG2066@1,COG2066@2 NA|NA|NA E Belongs to the glutaminase family MAG.T2.48_01849 521674.Plim_1504 4.1e-178 631.3 Bacteria qacA Bacteria COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.48_01850 639283.Snov_3895 1.1e-101 376.7 Xanthobacteraceae ansB GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.104 ko:K01424,ko:K22278 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1RCTE@1224,2VG80@28211,3EZ8J@335928,COG0252@1,COG0252@2 NA|NA|NA EJ Asparaginase MAG.T2.48_01851 102125.Xen7305DRAFT_00004000 5e-34 152.5 Bacteria ko:K07267 ko00000,ko02000 1.B.19.1 Bacteria COG3659@1,COG3659@2 NA|NA|NA M wide pore channel activity MAG.T2.48_01855 379066.GAU_2866 3.8e-106 392.9 Gemmatimonadetes bvgS 2.7.13.3 ko:K07677,ko:K07679 ko02020,ko02026,ko05133,map02020,map02026,map05133 M00474,M00477 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1ZUEC@142182,COG0642@1,COG0642@2,COG0745@1,COG0745@2,COG2198@1,COG2198@2,COG2202@1,COG2202@2 NA|NA|NA T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) MAG.T2.48_01856 794903.OPIT5_06705 1.8e-142 513.1 Opitutae ybaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03455 ko00000 2.A.37 Bacteria 3K8Q4@414999,46UN8@74201,COG1226@1,COG1226@2,COG4651@1,COG4651@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T2.48_01857 1216007.AOPM01000025_gene3292 1e-15 89.7 Pseudoalteromonadaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1MZNH@1224,1S8RQ@1236,2Q2HZ@267888,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity MAG.T2.48_01858 1173022.Cri9333_2288 1.1e-18 99.0 Oscillatoriales rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0040007,GO:0042594,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1G7SA@1117,1HC43@1150,COG0254@1,COG0254@2 NA|NA|NA J Binds the 23S rRNA MAG.T2.48_01859 1142394.PSMK_19340 6.2e-85 321.2 Planctomycetes prfB GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.1.80,3.1.1.61 ko:K02835,ko:K02836,ko:K02839,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03012 Bacteria 2IY77@203682,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA MAG.T2.48_01862 1085623.GNIT_1102 5.1e-142 511.1 Alteromonadaceae glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 iG2583_1286.G2583_3081,iIT341.HP0183 Bacteria 1MUIS@1224,1RMHQ@1236,4641N@72275,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism MAG.T2.48_01864 351160.RCIA88 2.5e-19 102.1 Methanomicrobia ogt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.1.63,3.1.21.7 ko:K00567,ko:K05982 ko00000,ko01000,ko03400 Archaea 2N9ZT@224756,2XZSR@28890,COG0350@1,arCOG02724@2157 NA|NA|NA L PFAM Methylated-DNA- protein -cysteine S-methyltransferase MAG.T2.48_01865 1121878.AUGL01000024_gene3725 9.5e-143 514.6 Bacteria 3.2.1.31,3.2.1.45 ko:K01195,ko:K01201,ko:K07107,ko:K20276 ko00040,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko02024,ko04142,map00040,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map02024,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R01498,R04979,R07818,R08127,R08260,R10830 RC00055,RC00059,RC00171,RC00451,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 GH30 Bacteria COG0824@1,COG0824@2,COG1520@1,COG1520@2,COG2133@1,COG2133@2,COG2273@1,COG2273@2,COG3291@1,COG3291@2,COG3507@1,COG3507@2,COG3866@1,COG3866@2,COG4733@1,COG4733@2 NA|NA|NA G Pectate lyase MAG.T2.48_01866 1142394.PSMK_01450 7.9e-143 513.8 Planctomycetes ugd 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXM4@203682,COG1004@1,COG1004@2 NA|NA|NA C Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T2.48_01867 498211.CJA_2465 1.3e-16 92.4 Cellvibrio hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1FHCB@10,1RFWH@1224,1S5GE@1236,COG0776@1,COG0776@2 NA|NA|NA L Bacterial DNA-binding protein MAG.T2.48_01868 32051.SynWH7803_1249 9.9e-65 253.8 Synechococcus murQ GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009254,GO:0016787,GO:0016801,GO:0016803,GO:0016829,GO:0016835,GO:0030203,GO:0043170,GO:0046348,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901575 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 iECH74115_1262.ECH74115_3658,iECSP_1301.ECSP_3375,iECs_1301.ECs3299,iG2583_1286.G2583_2959 Bacteria 1G1DR@1117,1GYHZ@1129,COG2103@1,COG2103@2 NA|NA|NA H Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate MAG.T2.48_01869 1210884.HG799469_gene14157 2e-135 490.0 Bacteria 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T2.48_01870 1142394.PSMK_02040 1.4e-90 339.7 Planctomycetes adoK GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2683 Bacteria 2IXGC@203682,COG0524@1,COG0524@2 NA|NA|NA H PFAM PfkB MAG.T2.48_01872 1128421.JAGA01000001_gene2194 3.4e-134 485.3 unclassified Bacteria hutH 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 2NNRU@2323,COG2986@1,COG2986@2 NA|NA|NA E Aromatic amino acid lyase MAG.T2.48_01873 44056.XP_009034826.1 8.8e-37 161.8 Eukaryota Eukaryota 2E3BA@1,2SAF2@2759 NA|NA|NA S FG-GAP repeat MAG.T2.48_01874 468059.AUHA01000002_gene706 3.1e-207 728.0 Sphingobacteriia hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_0688 Bacteria 1IR41@117747,4NF2P@976,COG2987@1,COG2987@2 NA|NA|NA E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate MAG.T2.48_01875 765420.OSCT_2703 1.5e-27 131.3 Chloroflexia 2.7.13.3 ko:K02482 ko00000,ko01000,ko01001,ko02022 Bacteria 2G7Y4@200795,374VX@32061,COG0745@1,COG0745@2,COG4191@1,COG4191@2 NA|NA|NA T histidine kinase A domain protein MAG.T2.48_01876 1267533.KB906738_gene2403 1.2e-30 141.0 Bacteria 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria COG2208@1,COG2208@2,COG3437@1,COG3437@2 NA|NA|NA T response regulator, receiver MAG.T2.48_01877 1000565.METUNv1_01028 7.1e-69 267.7 Rhodocyclales sua5 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1MVPM@1224,2KUUI@206389,2VIFT@28216,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine MAG.T2.48_01878 1142394.PSMK_18420 1.1e-80 307.8 Planctomycetes tolC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 2IZ8Q@203682,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T2.48_01881 1123242.JH636434_gene4351 1.2e-21 110.5 Planctomycetes rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 2IZRM@203682,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit MAG.T2.48_01882 1268237.G114_14746 4.9e-30 138.3 Aeromonadales rsmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 ko:K15984 ko00000,ko01000,ko03009 Bacteria 1MX8Z@1224,1RMIB@1236,1Y46C@135624,COG0742@1,COG0742@2 NA|NA|NA J Specifically methylates the guanosine in position 1516 of 16S rRNA MAG.T2.48_01883 767434.Fraau_2990 1.1e-158 566.6 Xanthomonadales cbs 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738,ko:K12339,ko:K18926 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338,M00715 R00891,R00897,R01290,R03132,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.3.30 Bacteria 1MUBE@1224,1RN6J@1236,1X4GC@135614,COG0031@1,COG0031@2,COG0517@1,COG0517@2 NA|NA|NA E Cystathionine beta-synthase MAG.T2.48_01884 454957.IA64_02780 1.7e-131 476.1 Xanthomonadales metC GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU57@1224,1RMCV@1236,1X4AH@135614,COG0626@1,COG0626@2 NA|NA|NA E cystathionine MAG.T2.48_01887 530564.Psta_1981 6.4e-11 76.6 Planctomycetes Bacteria 2EZEY@1,2J226@203682,33SK3@2 NA|NA|NA MAG.T2.48_01888 530564.Psta_1982 1.4e-10 72.8 Planctomycetes ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2J3QF@203682,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR MAG.T2.48_01889 1485545.JQLW01000010_gene1521 2.1e-09 68.9 Proteobacteria exbD2 ko:K03559,ko:K03560 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1N0ZA@1224,COG0848@1,COG0848@2 NA|NA|NA U biopolymer transport protein MAG.T2.48_01890 530564.Psta_1989 3.7e-35 155.2 Planctomycetes ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2J2RX@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family MAG.T2.48_01892 314230.DSM3645_19318 6.6e-18 98.6 Planctomycetes ko:K02674,ko:K07114 ko00000,ko02000,ko02035,ko02044 1.A.13.2.2,1.A.13.2.3 Bacteria 2J0MU@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain MAG.T2.48_01893 1142394.PSMK_22410 3.9e-70 271.6 Planctomycetes pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2IWYC@203682,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP MAG.T2.48_01894 1142394.PSMK_22400 8.8e-40 170.2 Planctomycetes frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2IYYY@203682,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another MAG.T2.48_01895 661478.OP10G_1178 4.4e-77 296.2 Bacteria Bacteria COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process MAG.T2.48_01896 401526.TcarDRAFT_0564 4.5e-35 154.5 Negativicutes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,4H4DR@909932,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes MAG.T2.48_01897 338966.Ppro_3639 2.6e-215 755.4 Deltaproteobacteria 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1MU08@1224,2WJ4J@28221,42M2R@68525,COG2217@1,COG2217@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T2.48_01899 1396141.BATP01000007_gene5791 1.1e-13 84.3 Bacteria 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria COG0265@1,COG0265@2 NA|NA|NA O serine-type endopeptidase activity MAG.T2.48_01900 446470.Snas_0032 3e-06 60.1 Bacteria Bacteria COG5563@1,COG5563@2 NA|NA|NA MAG.T2.48_01901 518766.Rmar_2319 2.9e-08 66.2 Bacteroidetes Bacteria 4PMRI@976,COG1319@1,COG1319@2 NA|NA|NA C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM MAG.T2.48_01902 497965.Cyan7822_0583 3.1e-11 76.3 Cyanothece 3.2.1.22,3.4.24.40 ko:K01406,ko:K07407,ko:K21449 ko00052,ko00561,ko00600,ko00603,ko01503,map00052,map00561,map00600,map00603,map01503 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 Bacteria 1GC1J@1117,3KJVM@43988,COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG5492@1,COG5492@2 NA|NA|NA QU Polymorphic membrane protein Chlamydia MAG.T2.48_01903 1142394.PSMK_25560 1.3e-240 839.3 Planctomycetes thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IXFR@203682,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) MAG.T2.48_01904 1142394.PSMK_16260 2.5e-37 162.5 Planctomycetes infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2IZ68@203682,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins MAG.T2.48_01905 1223543.GP2_040_00060 7.9e-19 100.5 Gordoniaceae argR GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0032991,GO:0032993,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140110,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 2GKA5@201174,4GAM7@85026,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes MAG.T2.48_01906 1202962.KB907177_gene2793 1.5e-75 290.0 Gammaproteobacteria argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1MVJ6@1224,1RNMX@1236,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde MAG.T2.48_01907 243277.VC_2643 3e-45 189.1 Vibrionales argB GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 Bacteria 1MU17@1224,1RNKK@1236,1XSF2@135623,COG0548@1,COG0548@2 NA|NA|NA F Belongs to the acetylglutamate kinase family. ArgB subfamily MAG.T2.48_01908 1236541.BALL01000036_gene3624 1e-80 307.0 Shewanellaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUFM@1224,1RQ59@1236,2Q9YD@267890,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline MAG.T2.48_01909 1128912.GMES_0132 6.4e-153 547.4 Alteromonadaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1MV0Y@1224,1RMEC@1236,464YE@72275,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily MAG.T2.48_01910 283942.IL0616 2.6e-192 678.7 Idiomarinaceae argH GO:0003674,GO:0003824,GO:0004042,GO:0004056,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K00619,ko:K01755,ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844,M00845 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iAF987.Gmet_0946 Bacteria 1MUTU@1224,1RMA3@1236,2QFCX@267893,COG0165@1,COG0165@2,COG1246@1,COG1246@2 NA|NA|NA E belongs to the lyase 1 family. Argininosuccinate lyase subfamily MAG.T2.48_01911 552811.Dehly_0926 3.2e-74 285.8 Dehalococcoidia argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 2G64K@200795,34CYK@301297,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate MAG.T2.48_01913 1142394.PSMK_20720 1.2e-111 409.8 Planctomycetes pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_1415,iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176 Bacteria 2IXSW@203682,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily MAG.T2.48_01914 1142394.PSMK_23740 2.2e-39 169.1 Planctomycetes rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZD3@203682,COG0203@1,COG0203@2 NA|NA|NA J ribosomal protein l17 MAG.T2.48_01915 1142394.PSMK_23760 4.4e-114 417.9 Planctomycetes rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXPQ@203682,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.48_01916 1142394.PSMK_23770 2e-43 181.8 Planctomycetes rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZCP@203682,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome MAG.T2.48_01917 1142394.PSMK_23780 1.7e-31 142.1 Planctomycetes rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZK8@203682,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MAG.T2.48_01918 481448.Minf_1443 1.5e-07 60.8 Bacteria rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family MAG.T2.48_01919 883.DvMF_2132 1.2e-21 108.6 Desulfovibrionales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1MZFU@1224,2MCF7@213115,2WPZK@28221,42TRU@68525,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T2.48_01920 1245475.ANAE01000199_gene2780 6.7e-53 214.5 Streptosporangiales map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKKB@201174,4EIBF@85012,COG0024@1,COG0024@2 NA|NA|NA J Metallopeptidase family M24 MAG.T2.48_01921 1142394.PSMK_28990 3.9e-137 495.0 Planctomycetes secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2IXN6@203682,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently MAG.T2.48_01922 1142394.PSMK_29000 6e-23 114.0 Planctomycetes rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZM0@203682,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA MAG.T2.48_01923 1142394.PSMK_29010 1.4e-43 183.3 Planctomycetes rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ7J@203682,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body MAG.T2.48_01924 926692.AZYG01000040_gene1579 3.1e-30 137.9 Halanaerobiales rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,24JCS@186801,3WBWI@53433,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance MAG.T2.48_01925 1142394.PSMK_29030 1.4e-37 162.9 Planctomycetes rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ8X@203682,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center MAG.T2.48_01926 1203606.HMPREF1526_02683 8.2e-32 143.3 Clostridiaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,24HCP@186801,36I6W@31979,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit MAG.T2.48_01927 521674.Plim_0490 2.6e-12 77.4 Planctomycetes rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0QE@203682,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site MAG.T2.48_01928 1142394.PSMK_29060 3.7e-47 195.3 Planctomycetes rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZCM@203682,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits MAG.T2.48_01929 981383.AEWH01000035_gene862 1.7e-20 105.5 Bacilli rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit MAG.T2.48_01930 1142394.PSMK_29080 3e-39 167.9 Planctomycetes rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZMA@203682,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome MAG.T2.48_01931 1142394.PSMK_29090 1.8e-18 98.6 Planctomycetes rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0WD@203682,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA MAG.T2.48_01933 1142394.PSMK_29110 1.1e-47 196.1 Planctomycetes rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZPH@203682,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs MAG.T2.48_01934 1142394.PSMK_29120 6.4e-80 303.9 Planctomycetes rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IWWU@203682,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation MAG.T2.48_01935 1142394.PSMK_29130 9.8e-26 122.9 Planctomycetes rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J023@203682,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome MAG.T2.48_01936 530564.Psta_2604 1.2e-27 129.0 Planctomycetes rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0BB@203682,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA MAG.T2.48_01937 1142394.PSMK_29150 8.9e-92 343.6 Planctomycetes rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IXD9@203682,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity MAG.T2.48_01938 93060.P9215_18281 7.7e-13 79.7 Cyanobacteria rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1G7XC@1117,1MMMB@1212,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome MAG.T2.48_01939 1142394.PSMK_29170 9.5e-49 200.3 Planctomycetes rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IYU2@203682,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel MAG.T2.48_01940 1142394.PSMK_29180 4.7e-51 208.0 Planctomycetes rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IY9T@203682,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit MAG.T2.48_01941 1142394.PSMK_29190 4.8e-40 170.2 Planctomycetes rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZQR@203682,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes MAG.T2.48_01944 1142394.PSMK_20520 2.2e-62 245.7 Planctomycetes Bacteria 2J55H@203682,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 MAG.T2.48_01945 1123508.JH636439_gene614 6.2e-13 82.4 Planctomycetes Bacteria 2C7TA@1,2IXIJ@203682,2Z9TR@2 NA|NA|NA MAG.T2.48_01946 1142394.PSMK_09570 2.4e-78 299.3 Planctomycetes yhaM ko:K03698 ko00000,ko01000,ko03019 Bacteria 2IX5B@203682,COG3481@1,COG3481@2 NA|NA|NA S Nucleic acid binding MAG.T2.48_01947 493475.GARC_5284 1.4e-62 247.7 Alteromonadaceae ko:K02660 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko02035,ko02044 Bacteria 1MV70@1224,1RPPQ@1236,465BG@72275,COG1858@1,COG1858@2 NA|NA|NA P Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.48_01948 1142394.PSMK_13700 2.4e-55 222.6 Planctomycetes nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2IYWH@203682,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T2.48_01949 344747.PM8797T_12373 1.8e-24 120.9 Planctomycetes Bacteria 2IYTT@203682,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T2.48_01950 1142394.PSMK_12460 5.7e-127 461.5 Planctomycetes lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2IXHX@203682,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family MAG.T2.48_01951 635013.TherJR_2349 3.7e-109 401.7 Peptococcaceae pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iJN678.pfkA Bacteria 1TPF4@1239,249AM@186801,2607Y@186807,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T2.48_01952 1142394.PSMK_26450 1.2e-40 173.7 Planctomycetes 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2J080@203682,COG0241@1,COG0241@2 NA|NA|NA E HAD-hyrolase-like MAG.T2.48_01953 1142394.PSMK_06170 1.8e-47 196.8 Planctomycetes rfaF 2.7.1.167,2.7.7.70 ko:K02841,ko:K02843,ko:K02849,ko:K03272 ko00540,ko01100,map00540,map01100 M00064,M00080 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 2IXD5@203682,COG0859@1,COG0859@2 NA|NA|NA M PFAM glycosyl transferase family 9 MAG.T2.48_01956 595460.RRSWK_02101 4.5e-63 249.6 Planctomycetes Bacteria 2IWUD@203682,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA T Serine threonine protein kinase MAG.T2.48_01957 234267.Acid_1209 5.7e-21 107.8 Acidobacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 3Y589@57723,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.48_01958 1142394.PSMK_15030 9.5e-39 167.2 Planctomycetes plsY 2.3.1.15 ko:K03977,ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko03009 Bacteria 2J0DJ@203682,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP MAG.T2.48_01959 1142394.PSMK_15990 7.1e-142 510.8 Planctomycetes purB 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXU4@203682,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily MAG.T2.48_01960 192875.XP_004347829.1 2.1e-29 136.0 Opisthokonta Opisthokonta 38EAH@33154,COG1335@1,KOG4044@2759 NA|NA|NA Q isochorismatase domain-containing protein MAG.T2.48_01962 247490.KSU1_C1680 3.8e-26 125.2 Planctomycetes fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 2IZNA@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) MAG.T2.48_01963 1142394.PSMK_06150 5.4e-54 218.4 Planctomycetes manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZ3A@203682,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase MAG.T2.48_01964 1121396.KB893110_gene1904 1.8e-11 77.4 Desulfobacterales Bacteria 1RJPM@1224,2MN82@213118,2WPCS@28221,42T21@68525,COG5434@1,COG5434@2 NA|NA|NA M Right handed beta helix region MAG.T2.48_01965 682795.AciX8_3759 2.7e-15 89.0 Acidobacteriia ko:K03088 ko00000,ko03021 Bacteria 2JMNZ@204432,3Y7HT@57723,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase sigma factor MAG.T2.48_01968 1142394.PSMK_30500 3e-217 761.1 Planctomycetes atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2IY7P@203682,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits MAG.T2.48_01970 1242864.D187_007737 5.1e-125 455.3 Myxococcales Bacteria 1Q3C4@1224,2X49B@28221,2YYJ7@29,4393F@68525,COG1164@1,COG1164@2 NA|NA|NA E Oligoendopeptidase f MAG.T2.48_01972 1040987.AZUY01000035_gene4221 2.1e-09 71.2 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis MAG.T2.48_01973 335543.Sfum_2158 2.2e-08 67.4 Deltaproteobacteria 2.7.11.1 ko:K08884 ko00000,ko01000,ko01001 Bacteria 1NT97@1224,2WNJD@28221,42RMY@68525,COG3391@1,COG3391@2 NA|NA|NA G NHL repeat MAG.T2.48_01975 439235.Dalk_2235 2e-70 272.3 Bacteria Bacteria COG0863@1,COG0863@2 NA|NA|NA L N-4 methylation of cytosine MAG.T2.48_01977 1142394.PSMK_07060 1.5e-34 153.3 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.48_01979 215803.DB30_2691 9.8e-69 268.1 Myxococcales MA20_40330 ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MXA3@1224,2WKAJ@28221,2YUTN@29,42PS8@68525,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like MAG.T2.48_01980 414684.RC1_1446 1.3e-48 199.9 Rhodospirillales ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MUIM@1224,2JRRR@204441,2TRHM@28211,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities MAG.T2.48_01981 118161.KB235922_gene3936 3.8e-12 79.0 Bacteria Bacteria 2C4HM@1,2ZFRV@2 NA|NA|NA MAG.T2.48_01982 1267534.KB906754_gene2559 9.4e-16 91.7 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T2.48_01983 378806.STAUR_6227 1.6e-71 276.6 Myxococcales rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264,2.1.1.72 ko:K00571,ko:K06969,ko:K12297 R07234 RC00003 ko00000,ko01000,ko02048,ko03009 Bacteria 1QW1V@1224,2WJXM@28221,2YWQY@29,42Q3P@68525,COG1092@1,COG1092@2 NA|NA|NA H Belongs to the methyltransferase superfamily MAG.T2.48_01984 452637.Oter_1547 0.0 1114.4 Opitutae hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 3K82Q@414999,46S7R@74201,COG3808@1,COG3808@2 NA|NA|NA C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force MAG.T2.48_01985 794903.OPIT5_25715 1e-16 94.4 Opitutae dedA Bacteria 3K9QN@414999,46YJH@74201,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T2.48_01986 546274.EIKCOROL_02120 2.2e-13 83.2 Neisseriales dedA Bacteria 1R6V4@1224,2KQ67@206351,2VMXP@28216,COG0586@1,COG0586@2 NA|NA|NA S Psort location CytoplasmicMembrane, score MAG.T2.48_01987 391625.PPSIR1_03638 8.4e-65 255.0 Deltaproteobacteria Bacteria 1QXGV@1224,2WNC6@28221,42RIF@68525,COG0457@1,COG0457@2 NA|NA|NA S ASPIC and UnbV MAG.T2.48_01991 1123242.JH636435_gene1286 2.4e-35 156.4 Planctomycetes ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IY79@203682,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T2.48_01992 1048834.TC41_0613 2.3e-13 82.0 Bacilli ytrA ko:K07979 ko00000,ko03000 Bacteria 1VFD0@1239,4HNIT@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional MAG.T2.48_01993 627192.SLG_10980 2e-185 655.6 Sphingomonadales rtcR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K14414 ko00000,ko03000 Bacteria 1MX6U@1224,2K2BF@204457,2U1UG@28211,COG4650@1,COG4650@2 NA|NA|NA KT regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA MAG.T2.48_01994 497964.CfE428DRAFT_5214 3.6e-69 268.1 Verrucomicrobia rsr ko:K11089 ko05322,map05322 ko00000,ko00001 Bacteria 46UN1@74201,COG2425@1,COG2425@2 NA|NA|NA S TROVE domain MAG.T2.48_01995 497964.CfE428DRAFT_5214 5.1e-93 347.8 Verrucomicrobia rsr ko:K11089 ko05322,map05322 ko00000,ko00001 Bacteria 46UN1@74201,COG2425@1,COG2425@2 NA|NA|NA S TROVE domain MAG.T2.48_01996 497964.CfE428DRAFT_5215 1.9e-201 708.8 Verrucomicrobia rtcB 6.5.1.3 ko:K14415 ko00000,ko01000,ko03016 Bacteria 46STD@74201,COG1690@1,COG1690@2 NA|NA|NA S tRNA-splicing ligase RtcB MAG.T2.48_01997 338963.Pcar_2836 6.4e-84 317.8 Desulfuromonadales rtcA GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 ko:K01974 ko00000,ko01000 Bacteria 1MX7Q@1224,2WKZ3@28221,42MZG@68525,43UBA@69541,COG0430@1,COG0430@2 NA|NA|NA H Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP MAG.T2.48_02000 525904.Tter_1994 1.8e-36 159.5 Bacteria 2.3.1.128,2.3.1.82 ko:K00663,ko:K03790 ko00000,ko01000,ko01504,ko03009 Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T2.48_02001 1280944.HY17_13165 7.7e-07 62.0 Hyphomonadaceae Bacteria 1RAI6@1224,2U6BK@28211,43ZSF@69657,COG3350@1,COG3350@2 NA|NA|NA S monooxygenase activity MAG.T2.48_02003 1142394.PSMK_24940 2.6e-195 688.7 Planctomycetes gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 2IXGA@203682,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 MAG.T2.48_02004 257310.BB4907 1.5e-22 114.4 Alcaligenaceae Bacteria 1QU8G@1224,2WGIU@28216,3T1DB@506,COG1160@1,COG1160@2 NA|NA|NA S Domain of unknown function (DUF3482) MAG.T2.48_02006 344747.PM8797T_32060 1.1e-07 62.8 Planctomycetes tatA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2J14F@203682,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system MAG.T2.48_02007 56780.SYN_02504 2.1e-63 250.0 Deltaproteobacteria mltA GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K08304 ko00000,ko01000,ko01011 GH102 iECABU_c1320.ECABU_c30840 Bacteria 1MXD4@1224,2WKKF@28221,42P7C@68525,COG2821@1,COG2821@2 NA|NA|NA M PFAM MltA domain protein MAG.T2.48_02008 1123508.JH636440_gene2098 7.8e-121 441.0 Planctomycetes purH 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IXB5@203682,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH MAG.T2.48_02010 1142394.PSMK_16100 1.7e-79 304.7 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IXKI@203682,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.48_02012 1142394.PSMK_06260 3.3e-39 169.9 Bacteria Bacteria COG0308@1,COG0308@2 NA|NA|NA E peptide catabolic process MAG.T2.48_02015 1237500.ANBA01000012_gene5255 2.6e-15 90.9 Actinobacteria Bacteria 2GIV0@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.48_02016 1303518.CCALI_01699 1.3e-78 300.1 Bacteria prpB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 ko:K03417 ko00640,map00640 R00409 RC00286,RC00287 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407 Bacteria COG2513@1,COG2513@2 NA|NA|NA G methylisocitrate lyase activity MAG.T2.48_02017 1239962.C943_01492 4.9e-40 171.4 Bacteroidetes cpcT GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017006,GO:0017007,GO:0017009,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K05383 ko00196,ko01100,map00196,map01100 ko00000,ko00001,ko00194 Bacteria 2CCNY@1,2Z877@2,4NR3D@976 NA|NA|NA E CpeT/CpcT family (DUF1001) MAG.T2.48_02018 644966.Tmar_1299 2.7e-91 342.4 Clostridiales incertae sedis citZ 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPS@1239,24865@186801,3WD3X@538999,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain MAG.T2.48_02019 880073.Calab_1754 3.3e-107 396.4 unclassified Bacteria 3.2.1.4,3.4.21.66 ko:K01179,ko:K08651 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01002,ko03110 GH5,GH9 Bacteria 2NQ6Y@2323,COG1404@1,COG1404@2,COG3291@1,COG3291@2 NA|NA|NA M PKD domain MAG.T2.48_02020 1089548.KI783301_gene3133 5.5e-73 281.2 Bacillales incertae sedis hbdA 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 1TPJS@1239,3WF7J@539002,4HA59@91061,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MAG.T2.48_02021 1463936.JOJI01000059_gene6084 9e-31 140.6 Actinobacteria Bacteria 2GRGB@201174,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase-like domain MAG.T2.48_02022 1227497.C491_01297 3.9e-71 275.4 Halobacteria solA Archaea 23S19@183963,2XUM9@28890,COG0665@1,arCOG00755@2157 NA|NA|NA E COG0665 Glycine D-amino acid oxidases (deaminating) MAG.T2.48_02024 864702.OsccyDRAFT_4565 7e-53 215.3 Oscillatoriales ampG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria 1G1K4@1117,1H9RK@1150,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.48_02025 714943.Mucpa_1894 8.6e-36 156.8 Sphingobacteriia Bacteria 1IXGY@117747,4NNH0@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T2.48_02027 1123242.JH636436_gene620 8.6e-54 218.0 Planctomycetes ko:K07814 ko00000,ko02022 Bacteria 2IXR5@203682,COG3437@1,COG3437@2 NA|NA|NA T metal-dependent phosphohydrolase HD sub domain MAG.T2.48_02031 443143.GM18_2340 2.4e-96 359.4 Proteobacteria Bacteria 1QWM9@1224,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T2.48_02032 1232410.KI421426_gene1469 3.2e-16 92.4 Desulfuromonadales Bacteria 1MZYK@1224,2WR6C@28221,32Y28@2,42TR5@68525,43UQM@69541,COG1226@1 NA|NA|NA P Ion channel MAG.T2.48_02034 404589.Anae109_2025 7.9e-262 909.8 Myxococcales tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUEY@1224,2WINJ@28221,2YUJ3@29,42M80@68525,COG0021@1,COG0021@2 NA|NA|NA H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate MAG.T2.48_02035 247490.KSU1_B0456 6.3e-45 187.2 Planctomycetes rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2621 Bacteria 2IZSB@203682,COG0698@1,COG0698@2 NA|NA|NA G Ribose/Galactose Isomerase MAG.T2.48_02036 1183438.GKIL_2779 2.9e-29 136.0 Cyanobacteria fkpA 5.2.1.8 ko:K01802,ko:K03772 ko00000,ko01000,ko03110 Bacteria 1G5T1@1117,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T2.48_02038 268407.PWYN_18480 8.6e-119 433.7 Paenibacillaceae ampS5 ko:K19689 ko00000,ko01000,ko01002 Bacteria 1TP65@1239,26SBU@186822,4HBUQ@91061,COG2309@1,COG2309@2 NA|NA|NA E aminopeptidase MAG.T2.48_02039 756272.Plabr_0503 8.7e-37 160.6 Planctomycetes 5.4.2.6 ko:K01838 ko00500,map00500 R02728,R11310 RC00408 ko00000,ko00001,ko01000 Bacteria 2IZIM@203682,COG0637@1,COG0637@2 NA|NA|NA S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED MAG.T2.48_02040 378806.STAUR_2233 1.7e-92 346.3 Myxococcales ltaA 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 1MWCR@1224,2WIQP@28221,2YUBW@29,42MZS@68525,COG2008@1,COG2008@2 NA|NA|NA E Threonine aldolase MAG.T2.48_02043 1142394.PSMK_03650 2.2e-39 171.0 Bacteria ko:K03424 ko00000,ko01000 Bacteria COG0731@1,COG0731@2 NA|NA|NA C radical SAM domain protein MAG.T2.48_02044 1382359.JIAL01000001_gene1066 5.2e-36 157.9 Acidobacteriia Bacteria 2JKRK@204432,3Y4AI@57723,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF1572) MAG.T2.48_02045 1142394.PSMK_23020 1.1e-28 134.0 Planctomycetes lonD 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 2J03T@203682,COG2802@1,COG2802@2 NA|NA|NA S Peptidase S16, lon domain protein MAG.T2.48_02046 582515.KR51_00017730 9.4e-18 97.8 Cyanobacteria ppiB 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1G5BD@1117,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.48_02047 1469607.KK073768_gene1384 8.3e-36 157.5 Nostocales 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1G6CG@1117,1HUBP@1161,COG0500@1,COG0500@2,COG0546@1,COG0546@2 NA|NA|NA Q Nodulation protein S (NodS) MAG.T2.48_02048 999415.HMPREF9943_00127 1.9e-43 182.6 Erysipelotrichia lemA ko:K03744 ko00000 Bacteria 1V3Z0@1239,3VQJK@526524,COG1704@1,COG1704@2 NA|NA|NA S LemA family MAG.T2.48_02049 1142394.PSMK_01700 2.2e-113 415.6 Planctomycetes ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IXY1@203682,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing MAG.T2.48_02050 1000565.METUNv1_02114 5.2e-19 101.7 Betaproteobacteria phoD 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1NITU@1224,2W3YR@28216,COG3540@1,COG3540@2 NA|NA|NA P Laminin B (Domain IV) MAG.T2.48_02051 1142394.PSMK_26820 3.9e-68 266.9 Planctomycetes Bacteria 2IXFV@203682,COG1452@1,COG1452@2 NA|NA|NA M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane MAG.T2.48_02052 1166018.FAES_2019 2.5e-10 73.2 Cytophagia 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 47JTB@768503,4NIXM@976,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T2.48_02053 314345.SPV1_01712 4.3e-19 101.3 Proteobacteria ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825 Bacteria 1RD9J@1224,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin MAG.T2.48_02054 177437.HRM2_31230 1.3e-14 86.3 Desulfobacterales nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1N94P@1224,2MK59@213118,2WQP9@28221,42SEA@68525,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons MAG.T2.48_02055 1142394.PSMK_00390 1.9e-92 345.9 Planctomycetes ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2IXAG@203682,COG0552@1,COG0552@2 NA|NA|NA D Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) MAG.T2.48_02056 1142394.PSMK_16020 2.6e-09 69.3 Planctomycetes Bacteria 2IY7F@203682,COG4968@1,COG4968@2 NA|NA|NA NU Pfam:N_methyl_2 MAG.T2.48_02058 583355.Caka_0944 1.3e-149 537.3 Opitutae 3.6.4.13 ko:K03579 ko00000,ko01000 Bacteria 3K7J2@414999,46TMT@74201,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase C-terminal MAG.T2.48_02060 1458427.BAWN01000006_gene464 3.1e-243 848.2 Comamonadaceae mrpA/mrpB ko:K05559,ko:K05565 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1MW2M@1224,2VK56@28216,4A9ZV@80864,COG1009@1,COG1009@2 NA|NA|NA CP Na H antiporter MnhB subunit-related protein MAG.T2.48_02061 1458427.BAWN01000006_gene465 6.1e-39 167.2 Betaproteobacteria ko:K05559,ko:K05565,ko:K05566 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1REGG@1224,2VYKD@28216,COG2111@1,COG2111@2 NA|NA|NA P Domain related to MnhB subunit of Na+/H+ antiporter MAG.T2.48_02062 1458427.BAWN01000006_gene466 1.5e-32 146.0 Betaproteobacteria mrpC ko:K05567 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1NF6Q@1224,2VYVJ@28216,COG1006@1,COG1006@2 NA|NA|NA P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MAG.T2.48_02063 1458427.BAWN01000006_gene467 1.6e-165 589.3 Comamonadaceae mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05568 ko00000,ko02000 2.A.63.1,2.A.63.2 iSB619.SA_RS04615 Bacteria 1MURB@1224,2VH1Y@28216,4AAUG@80864,COG0651@1,COG0651@2 NA|NA|NA CP NADH Ubiquinone plastoquinone (Complex I) MAG.T2.48_02064 1458427.BAWN01000006_gene468 1.3e-25 122.5 Proteobacteria ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1NAFJ@1224,2DTGD@1,33K83@2 NA|NA|NA S Na+/H+ ion antiporter subunit MAG.T2.48_02065 1458427.BAWN01000006_gene469 2.1e-16 91.7 Bacteria ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria COG2212@1,COG2212@2 NA|NA|NA P antiporter activity MAG.T2.48_02066 1458427.BAWN01000006_gene470 3.5e-23 114.4 Comamonadaceae mrpG ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1MZ6Z@1224,2VVWW@28216,4AFTX@80864,COG1320@1,COG1320@2 NA|NA|NA P Na+/H+ antiporter subunit MAG.T2.48_02067 1142394.PSMK_04470 1.3e-71 276.6 Planctomycetes fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2IZCH@203682,COG1611@1,COG1611@2 NA|NA|NA NOU Possible lysine decarboxylase MAG.T2.48_02068 1142394.PSMK_11030 2e-131 476.1 Planctomycetes folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX24@203682,COG0285@1,COG0285@2 NA|NA|NA H folylpolyglutamate synthase MAG.T2.48_02069 1123322.KB904724_gene1948 5.1e-280 970.7 Actinobacteria leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T2.48_02070 344747.PM8797T_21358 4.4e-94 352.1 Bacteria Bacteria COG0464@1,COG0464@2 NA|NA|NA O ATPase activity MAG.T2.48_02075 1142394.PSMK_31050 3.8e-26 125.9 Planctomycetes Bacteria 2IZVM@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.48_02076 1142394.PSMK_31040 5.2e-30 139.8 Planctomycetes Bacteria 2IZ6E@203682,COG1305@1,COG1305@2 NA|NA|NA E transglutaminase domain protein MAG.T2.48_02078 1131814.JAFO01000001_gene2857 2.4e-58 233.4 Xanthobacteraceae pabB 2.6.1.85 ko:K01665,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 Bacteria 1MVBJ@1224,2TRWB@28211,3EYR5@335928,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I, N terminal region MAG.T2.48_02079 1089550.ATTH01000001_gene1987 4.5e-51 209.5 Bacteroidetes Bacteria 4NKIR@976,COG2866@1,COG2866@2,COG2931@1,COG2931@2,COG3291@1,COG3291@2 NA|NA|NA Q SMART Integrin alpha beta-propellor repeat protein MAG.T2.48_02080 583355.Caka_2519 0.0 1093.6 Opitutae ppdK 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7A5@414999,46TNN@74201,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family MAG.T2.48_02083 502025.Hoch_4498 1e-32 146.4 Myxococcales hit ko:K02503 ko00000,ko04147 Bacteria 1PDTP@1224,2WS0J@28221,2Z2ZP@29,42UAD@68525,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain MAG.T2.48_02084 869210.Marky_2090 2.8e-53 216.1 Deinococcus-Thermus nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 1WIHZ@1297,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family MAG.T2.48_02085 319795.Dgeo_2140 1.1e-20 107.5 Deinococcus-Thermus birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1WJDW@1297,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor MAG.T2.48_02088 1142394.PSMK_12550 3.1e-61 242.3 Planctomycetes ko:K03496 ko00000,ko03036,ko04812 Bacteria 2IX5Z@203682,COG1192@1,COG1192@2 NA|NA|NA D involved in chromosome partitioning MAG.T2.48_02091 1142394.PSMK_31030 2.3e-80 306.6 Planctomycetes murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2IYP2@203682,COG0728@1,COG0728@2 NA|NA|NA U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane MAG.T2.48_02092 1142394.PSMK_11680 2.9e-126 458.8 Planctomycetes mqnE GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXUS@203682,COG1060@1,COG1060@2 NA|NA|NA H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate MAG.T2.48_02093 595460.RRSWK_05134 2.8e-26 127.1 Bacteria Bacteria COG2374@1,COG2374@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2 NA|NA|NA S protein secretion MAG.T2.48_02094 1128421.JAGA01000001_gene2345 4.6e-23 116.7 Bacteria Bacteria COG1572@1,COG1572@2 NA|NA|NA NU bacterial-type flagellum-dependent cell motility MAG.T2.48_02095 864051.BurJ1DRAFT_0942 6e-27 128.3 Proteobacteria Bacteria 1P0W9@1224,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T2.48_02096 1283300.ATXB01000002_gene2888 5.3e-25 121.7 Bacteria Bacteria 2DP87@1,330Z8@2 NA|NA|NA MAG.T2.48_02097 1142394.PSMK_06240 1.2e-26 128.3 Bacteria Bacteria 2DD6P@1,2ZGSW@2 NA|NA|NA S PEP-CTERM motif MAG.T2.48_02098 1142394.PSMK_06230 1.3e-42 180.3 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.48_02099 1121889.AUDM01000002_gene473 2.6e-43 182.6 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.48_02100 1121889.AUDM01000002_gene473 1.1e-45 190.3 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.48_02101 1121889.AUDM01000002_gene473 4.4e-39 168.3 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.48_02104 2903.EOD33656 6.5e-39 167.2 Eukaryota 5.2.1.8 ko:K01802 ko00000,ko01000 Eukaryota COG0652@1,KOG0881@2759 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity MAG.T2.48_02105 502025.Hoch_6539 6.8e-12 79.7 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.48_02106 661478.OP10G_2239 2e-49 203.4 Bacteria 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.48_02107 1142394.PSMK_26710 6.4e-128 464.5 Planctomycetes gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2IX3U@203682,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T2.48_02108 640132.Srot_0399 9.7e-32 143.7 Actinobacteria hpt GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GMDZ@201174,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family MAG.T2.48_02109 1123236.KB899388_gene2083 8.4e-41 174.5 Alteromonadaceae Bacteria 1R5N9@1224,1RY8I@1236,28JIP@1,2Z82C@2,465MK@72275 NA|NA|NA S S1 P1 nuclease MAG.T2.48_02110 530564.Psta_4209 5.6e-61 241.5 Planctomycetes dnaJ1 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2IY4W@203682,COG0484@1,COG0484@2,COG2214@1,COG2214@2 NA|NA|NA O SMART Heat shock protein DnaJ MAG.T2.48_02111 330214.NIDE2245 5.1e-14 86.7 Bacteria Bacteria COG0348@1,COG0348@2 NA|NA|NA C 4 iron, 4 sulfur cluster binding MAG.T2.48_02113 1121957.ATVL01000014_gene1459 5.1e-35 156.8 Cytophagia Bacteria 47VHU@768503,4PHUI@976,COG5563@1,COG5563@2 NA|NA|NA MAG.T2.48_02114 1142394.PSMK_13590 2.6e-30 138.7 Planctomycetes ptsN 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IZ73@203682,COG1762@1,COG1762@2 NA|NA|NA G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 MAG.T2.48_02115 1142394.PSMK_05980 2.9e-46 193.0 Planctomycetes sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 2J09U@203682,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family MAG.T2.48_02116 1120983.KB894577_gene3541 2e-129 469.2 Rhodobiaceae metK GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 iJN746.PP_4967,iYL1228.KPN_03375 Bacteria 1JMYV@119043,1MUFQ@1224,2TR4P@28211,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme MAG.T2.48_02117 269799.Gmet_0749 2.4e-53 216.9 Deltaproteobacteria 3.4.21.66 ko:K08651,ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1MU3S@1224,2WKJS@28221,42N7D@68525,COG1404@1,COG1404@2 NA|NA|NA M Belongs to the peptidase S8 family MAG.T2.48_02118 886293.Sinac_6056 2.1e-31 142.1 Planctomycetes GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03617,ko:K08999 ko00000 Bacteria 2IZNE@203682,COG1259@1,COG1259@2 NA|NA|NA S Bifunctional nuclease MAG.T2.48_02119 661478.OP10G_1361 4.5e-27 128.3 Bacteria MA20_37750 3.1.3.10 ko:K07025,ko:K20866 ko00010,ko01120,map00010,map01120 R00947 RC00078 ko00000,ko00001,ko01000 Bacteria COG1011@1,COG1011@2 NA|NA|NA S phosphatase activity MAG.T2.48_02120 1142394.PSMK_21380 7.1e-70 271.6 Planctomycetes truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 ko00000,ko01000,ko03016 Bacteria 2IYMT@203682,COG0585@1,COG0585@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs MAG.T2.48_02122 580340.Tlie_1187 4.9e-42 177.6 Synergistetes tadA 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 Bacteria 3TB5H@508458,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) MAG.T2.48_02123 1142394.PSMK_07850 3.4e-29 136.0 Planctomycetes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IZ9K@203682,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes MAG.T2.48_02124 1142394.PSMK_10880 5.8e-45 188.0 Planctomycetes tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 2IZ3Q@203682,COG0084@1,COG0084@2 NA|NA|NA L COG0084 Mg-dependent DNase MAG.T2.48_02125 344747.PM8797T_11846 8.1e-69 266.9 Planctomycetes mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 2IYYJ@203682,COG3880@1,COG3880@2 NA|NA|NA C Cytochrome c7 and related cytochrome c MAG.T2.48_02126 357808.RoseRS_4140 4.4e-211 741.9 Chloroflexia hmeA ko:K00184 ko00000 5.A.3 Bacteria 2G6C1@200795,376FK@32061,COG0243@1,COG0243@2,COG0437@1,COG0437@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T2.48_02127 521674.Plim_3984 2.7e-187 661.8 Planctomycetes actC ko:K00185 ko00000 5.A.3 Bacteria 2IWYN@203682,COG5557@1,COG5557@2 NA|NA|NA C Polysulphide reductase MAG.T2.48_02128 502025.Hoch_2415 1.5e-43 183.0 Myxococcales actE Bacteria 1RDVX@1224,2WT1Y@28221,2Z0GX@29,42WYA@68525,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF3341) MAG.T2.48_02129 502025.Hoch_2415 2e-46 192.6 Myxococcales actE Bacteria 1RDVX@1224,2WT1Y@28221,2Z0GX@29,42WYA@68525,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF3341) MAG.T2.48_02130 1192034.CAP_2028 4.2e-77 295.4 Myxococcales actF Bacteria 1REHQ@1224,2WQ6N@28221,2YY91@29,42TZ1@68525,COG4531@1,COG4531@2 NA|NA|NA P ABC-type Zn2 transport system, periplasmic component surface adhesin MAG.T2.48_02132 314230.DSM3645_01971 1.1e-52 213.8 Planctomycetes ko:K07152 ko00000,ko03029 Bacteria 2IYYD@203682,COG1999@1,COG1999@2 NA|NA|NA S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems MAG.T2.48_02133 1123242.JH636436_gene296 2.5e-65 256.1 Planctomycetes coxB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275,ko:K17223 ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120 M00155,M00595 R00081,R10151 RC00016,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 2IXB7@203682,COG1622@1,COG1622@2,COG2010@1,COG2010@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T2.48_02134 521674.Plim_3990 1.6e-217 762.3 Planctomycetes coxA 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2IXCQ@203682,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B MAG.T2.48_02135 1123242.JH636436_gene298 1.4e-64 253.4 Planctomycetes coxC 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 2IYXN@203682,COG1845@1,COG1845@2 NA|NA|NA C Heme copper-type cytochrome quinol oxidase, subunit MAG.T2.48_02136 1089550.ATTH01000001_gene1165 2.1e-15 89.0 Bacteroidetes Order II. Incertae sedis ctaF 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 ko00000,ko00001,ko00002,ko01000 3.D.4.4 Bacteria 1FJMS@1100069,2EAMQ@1,338KI@2,4NYZ5@976 NA|NA|NA S Prokaryotic Cytochrome C oxidase subunit IV MAG.T2.48_02137 1455608.JDTH01000006_gene2516 6.7e-15 87.8 Halobacteria soxM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.3.12,1.9.3.1 ko:K02274,ko:K02827,ko:K02828,ko:K15408 ko00190,ko01100,map00190,map01100 M00155,M00416 R00081,R09492 RC00016,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Archaea 23S4J@183963,2XTBK@28890,COG0843@1,arCOG01237@2157 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T2.48_02138 207954.MED92_00080 3.1e-36 159.5 Oceanospirillales Bacteria 1N82C@1224,1RQQI@1236,1XINZ@135619,COG2128@1,COG2128@2 NA|NA|NA S Protein of unknown function (DUF3179) MAG.T2.48_02139 497964.CfE428DRAFT_2237 5.8e-56 224.9 Verrucomicrobia ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 iJN746.PP_0110,iSB619.SA_RS05465,iSFxv_1172.SFxv_0410,iYO844.BSU12080 Bacteria 46SQE@74201,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group MAG.T2.48_02140 671143.DAMO_1660 2.3e-25 124.0 unclassified Bacteria ctaA ko:K02259,ko:K03110 ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714 M00154,M00335 R07412 RC00769 ko00000,ko00001,ko00002,ko02044,ko03029 3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4 Bacteria 2NQ3D@2323,COG1612@1,COG1612@2 NA|NA|NA O Cytochrome oxidase assembly protein MAG.T2.48_02141 521674.Plim_4048 9.4e-62 244.6 Planctomycetes 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IXAS@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.48_02142 502025.Hoch_6539 1.2e-14 88.6 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.48_02144 861299.J421_2390 4.4e-69 268.5 Gemmatimonadetes Bacteria 1ZT6R@142182,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T2.48_02146 1379698.RBG1_1C00001G1364 3.9e-42 179.5 unclassified Bacteria macA ko:K02005 ko00000 Bacteria 2NP97@2323,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_02147 292459.STH976 3.2e-75 288.5 Clostridia macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,248EZ@186801,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T2.48_02148 575540.Isop_3019 4.8e-70 271.9 Planctomycetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IY2P@203682,COG0577@1,COG0577@2 NA|NA|NA V membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides MAG.T2.48_02149 1236959.BAMT01000001_gene1729 3.2e-88 332.8 Nitrosomonadales tolC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1NEHN@1224,2KKVJ@206350,2VYWE@28216,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.48_02151 1123242.JH636434_gene4975 3.3e-16 92.4 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZZP@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.48_02152 113395.AXAI01000021_gene3525 5.7e-19 100.9 Bradyrhizobiaceae 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1NGC8@1224,2TT3U@28211,3JTKY@41294,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T2.48_02153 196490.AUEZ01000031_gene2803 1.1e-128 466.5 Bradyrhizobiaceae Bacteria 1MW38@1224,2TVAB@28211,3JUMP@41294,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase MAG.T2.48_02155 278957.ABEA03000099_gene860 1.2e-06 60.8 Opitutae Bacteria 2CAB8@1,33EYG@2,3K9KC@414999,46XII@74201 NA|NA|NA MAG.T2.48_02156 521045.Kole_0634 8.5e-12 77.0 Thermotogae Bacteria 2DQ8V@1,2GE1T@200918,32UNN@2 NA|NA|NA MAG.T2.48_02158 1210884.HG799469_gene14229 9.4e-16 89.4 Bacteria fic ko:K04095 ko00000,ko03036 Bacteria COG2184@1,COG2184@2 NA|NA|NA D nucleotidyltransferase activity MAG.T2.48_02159 1247963.JPHU01000029_gene93 5.6e-102 377.5 Alphaproteobacteria Bacteria 1MVN5@1224,2TQK0@28211,COG2801@1,COG2801@2 NA|NA|NA L COG2801 Transposase and inactivated derivatives MAG.T2.48_02160 314260.PB2503_12544 6.5e-28 129.8 Alphaproteobacteria ko:K07483,ko:K07497 ko00000 Bacteria 1RGZ5@1224,2UAIS@28211,COG2963@1,COG2963@2 NA|NA|NA L COG2801 Transposase and inactivated derivatives MAG.T2.48_02162 575540.Isop_2455 7.6e-125 454.1 Planctomycetes ko:K06400 ko00000 Bacteria 2IYJH@203682,COG1961@1,COG1961@2 NA|NA|NA L Site-specific recombinase, DNA invertase Pin MAG.T2.48_02163 525903.Taci_1503 2e-38 165.6 Bacteria Bacteria COG3547@1,COG3547@2 NA|NA|NA L Transposase (IS116 IS110 IS902 family) MAG.T2.48_02166 1458275.AZ34_11090 2.1e-119 435.6 Comamonadaceae 2.1.1.113,2.1.1.37 ko:K00558,ko:K00590 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1P97D@1224,2WGY7@28216,4AJZW@80864,COG0863@1,COG0863@2 NA|NA|NA L DNA methylase MAG.T2.48_02167 391625.PPSIR1_04418 5.6e-65 254.6 Myxococcales ko:K07497 ko00000 Bacteria 1PBHA@1224,2WJFZ@28221,2YTXG@29,42MUE@68525,COG2801@1,COG2801@2 NA|NA|NA L COG2801 Transposase and inactivated derivatives MAG.T2.48_02168 1396141.BATP01000030_gene3773 2.4e-10 70.9 Bacteria Bacteria COG3250@1,COG3250@2,COG3387@1,COG3387@2 NA|NA|NA G glucan 1,4-alpha-glucosidase activity MAG.T2.48_02169 1142394.PSMK_22870 2.4e-55 221.9 Planctomycetes sucD GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iYO844.BSU16100 Bacteria 2IWYV@203682,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit MAG.T2.48_02170 290512.Paes_2385 4.8e-50 205.3 Chlorobi Bacteria 1FF87@1090,COG1262@1,COG1262@2 NA|NA|NA O Sulfatase-modifying factor enzyme 1 MAG.T2.48_02171 290512.Paes_2385 3.9e-50 205.7 Chlorobi Bacteria 1FF87@1090,COG1262@1,COG1262@2 NA|NA|NA O Sulfatase-modifying factor enzyme 1 MAG.T2.48_02172 290512.Paes_2385 3.1e-47 196.1 Chlorobi Bacteria 1FF87@1090,COG1262@1,COG1262@2 NA|NA|NA O Sulfatase-modifying factor enzyme 1 MAG.T2.48_02174 1173028.ANKO01000106_gene309 9.6e-92 344.7 Oscillatoriales ko:K06940,ko:K18475 ko00000,ko01000,ko02035 Bacteria 1G3ZQ@1117,1HAC7@1150,COG0727@1,COG0727@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0153) MAG.T2.48_02175 383372.Rcas_2043 2.7e-71 275.4 Chloroflexia glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 2G813@200795,376PT@32061,COG0580@1,COG0580@2 NA|NA|NA G Belongs to the MIP aquaporin (TC 1.A.8) family MAG.T2.48_02176 1128421.JAGA01000002_gene1917 4.1e-165 588.2 unclassified Bacteria glpD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2NP90@2323,COG0578@1,COG0578@2 NA|NA|NA C C-terminal domain of alpha-glycerophosphate oxidase MAG.T2.48_02177 243231.GSU2762 4.3e-174 617.8 Desulfuromonadales glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1MUP7@1224,2WIYZ@28221,42M9Z@68525,43U0G@69541,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate MAG.T2.48_02179 595460.RRSWK_02350 2.2e-21 109.0 Planctomycetes Bacteria 2EPR5@1,2J16K@203682,33HBM@2 NA|NA|NA MAG.T2.48_02180 1123508.JH636442_gene3946 4.8e-67 261.9 Planctomycetes moeB 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 2IWVB@203682,COG0476@1,COG0476@2 NA|NA|NA H involved in molybdopterin and thiamine biosynthesis family 2 MAG.T2.48_02182 530564.Psta_3616 1.4e-248 865.9 Planctomycetes Bacteria 2IXVV@203682,COG0243@1,COG0243@2 NA|NA|NA C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family MAG.T2.48_02183 886293.Sinac_0492 3.7e-50 204.5 Planctomycetes rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ7I@203682,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA MAG.T2.48_02184 1142394.PSMK_26560 9.2e-52 209.5 Planctomycetes rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZR1@203682,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit MAG.T2.48_02186 880526.KE386488_gene1465 1.8e-20 107.1 Bacteroidia Bacteria 28HW2@1,2FMR4@200643,2Z825@2,4NF6G@976 NA|NA|NA S Peptide-N-glycosidase F, N terminal MAG.T2.48_02187 1232410.KI421427_gene1301 7.2e-40 170.2 Desulfuromonadales rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1RCZ1@1224,2WPJY@28221,42SIR@68525,43UU0@69541,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T2.48_02188 1142394.PSMK_17290 7.5e-98 364.0 Planctomycetes plsX 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 ko:K03621,ko:K21576,ko:K21577 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IWUY@203682,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA MAG.T2.48_02189 1142394.PSMK_17280 1.9e-80 306.2 Planctomycetes fabH GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681 2.3.1.180 ko:K00648,ko:K11608 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iNJ661.Rv0533c Bacteria 2IXBG@203682,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T2.48_02190 130081.XP_005709226.1 2.5e-64 252.7 Eukaryota MCAT GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 2.3.1.39,2.7.1.147 ko:K00645,ko:K08074,ko:K12879 ko00010,ko00061,ko00333,ko01100,ko01110,ko01130,ko01200,ko01212,ko03013,ko03040,map00010,map00061,map00333,map01100,map01110,map01130,map01200,map01212,map03013,map03040 M00001,M00082,M00405,M00406 R01626,R05804,R09085,R09086,R11671 RC00002,RC00004,RC00017,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko03019,ko03041 Eukaryota COG0331@1,KOG2926@2759 NA|NA|NA I [acyl-carrier-protein] S-malonyltransferase activity MAG.T2.48_02192 1142394.PSMK_22760 1.7e-61 242.7 Planctomycetes Bacteria 2IXE0@203682,COG1028@1,COG1028@2 NA|NA|NA IQ with different specificities (related to short-chain alcohol MAG.T2.48_02193 1142394.PSMK_22750 1.2e-20 105.5 Planctomycetes acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 2J0V5@203682,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T2.48_02194 1268239.PALB_30810 1e-128 466.8 Pseudoalteromonadaceae fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Bacteria 1MU1X@1224,1RMDE@1236,2Q0IG@267888,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T2.48_02195 1131269.AQVV01000086_gene1706 8.8e-12 76.3 Bacteria fliN ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria COG1886@1,COG1886@2 NA|NA|NA N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation MAG.T2.48_02198 404589.Anae109_4136 3.3e-98 366.3 Myxococcales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1MW8K@1224,2WKQW@28221,2Z33Y@29,42NNC@68525,COG2304@1,COG2304@2 NA|NA|NA M Von Willebrand factor type A MAG.T2.48_02200 360911.EAT1b_1495 1.1e-16 93.6 Bacillales incertae sedis ko:K03088 ko00000,ko03021 Bacteria 1V4B8@1239,3WFST@539002,4HHCY@91061,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.48_02201 502025.Hoch_3156 5.4e-24 117.9 Proteobacteria Bacteria 1NYI6@1224,2E13Z@1,32WJ8@2 NA|NA|NA MAG.T2.48_02202 247490.KSU1_C0337 3.1e-188 665.2 Planctomycetes Bacteria 2J1PN@203682,COG3387@1,COG3387@2 NA|NA|NA G Glycosyl hydrolases family 15 MAG.T2.48_02203 926549.KI421517_gene3913 4.1e-40 172.6 Cytophagia metSY ko:K22491 ko00000,ko03000 Bacteria 47UR1@768503,4NRCW@976,COG5012@1,COG5012@2 NA|NA|NA S B12 binding domain MAG.T2.48_02204 1396418.BATQ01000012_gene4410 2.1e-26 126.3 Verrucomicrobiae Bacteria 2IV4T@203494,46ZIY@74201,COG4760@1,COG4760@2 NA|NA|NA S Bax inhibitor 1 like MAG.T2.48_02205 1142394.PSMK_07780 2.4e-158 565.5 Planctomycetes phoH ko:K07175 ko00000 Bacteria 2IYGC@203682,COG1875@1,COG1875@2 NA|NA|NA T PIN domain MAG.T2.48_02209 1380394.JADL01000002_gene1168 7.4e-25 120.9 Proteobacteria ko:K03088 ko00000,ko03021 Bacteria 1NY42@1224,COG1595@1,COG1595@2 NA|NA|NA K 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' MAG.T2.48_02210 1192034.CAP_1893 4.2e-58 232.3 Myxococcales yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVUN@1224,2WM6S@28221,2Z0CP@29,42MHJ@68525,COG0327@1,COG0327@2 NA|NA|NA C NIF3 (NGG1p interacting factor 3) MAG.T2.48_02211 521674.Plim_2404 2.3e-46 193.0 Planctomycetes glkA 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY6I@203682,COG1940@1,COG1940@2 NA|NA|NA GK PFAM ROK family MAG.T2.48_02212 1142394.PSMK_30710 9.2e-259 900.2 Planctomycetes Bacteria 2IYJA@203682,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.48_02213 1142394.PSMK_30700 9.4e-48 198.0 Planctomycetes ko:K18990 M00720 ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 Bacteria 2J4ZU@203682,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_02214 1223543.GP2_013_01180 1.6e-14 85.5 Gordoniaceae gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2IQJN@201174,4GEEY@85026,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T2.48_02215 886293.Sinac_6340 3.7e-141 508.4 Planctomycetes gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2IXW5@203682,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) MAG.T2.48_02217 1142394.PSMK_17540 2.3e-92 347.1 Planctomycetes yqfF ko:K07037 ko00000 Bacteria 2IYP7@203682,COG1480@1,COG1480@2 NA|NA|NA S PFAM Metal-dependent phosphohydrolase, HD MAG.T2.48_02218 518766.Rmar_0152 1.7e-32 146.7 Bacteroidetes Order II. Incertae sedis yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 1FJCA@1100069,4NM9H@976,COG1496@1,COG1496@2 NA|NA|NA S Belongs to the multicopper oxidase YfiH RL5 family MAG.T2.48_02220 595460.RRSWK_03751 3.3e-19 101.7 Bacteria Bacteria 2CXV0@1,32T2Q@2 NA|NA|NA MAG.T2.48_02221 5786.XP_003285756.1 2.1e-108 399.1 Amoebozoa GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046073,GO:0046385,GO:0046483,GO:0050797,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 R06613 RC00022,RC00332 ko00000,ko00001,ko01000 Eukaryota 2SRAF@2759,3XEH7@554915,COG1351@1 NA|NA|NA H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant MAG.T2.48_02223 1142394.PSMK_27510 8.2e-93 347.1 Planctomycetes appF ko:K02031,ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2IX9Z@203682,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily MAG.T2.48_02224 1142394.PSMK_21540 4.9e-53 215.7 Planctomycetes sprI 3.4.21.107 ko:K04771,ko:K08372 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IY5I@203682,COG0265@1,COG0265@2 NA|NA|NA O PDZ domain (Also known as DHR MAG.T2.48_02225 1142394.PSMK_07540 5.5e-68 264.6 Planctomycetes panB 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXV0@203682,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate MAG.T2.48_02226 1142394.PSMK_21300 8.5e-51 207.2 Bacteria Bacteria COG0491@1,COG0491@2 NA|NA|NA GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid MAG.T2.48_02227 1142394.PSMK_21310 5e-35 154.5 Planctomycetes coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZM2@203682,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate MAG.T2.48_02230 1089547.KB913013_gene744 2.1e-42 181.0 Cytophagia ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 47QPM@768503,4NQBS@976,COG3266@1,COG3266@2 NA|NA|NA S FG-GAP repeat MAG.T2.48_02231 1123355.JHYO01000003_gene2880 6.8e-25 120.6 Methylocystaceae Bacteria 1NAZV@1224,2E3ZS@1,2UGW3@28211,32YWP@2,36YRJ@31993 NA|NA|NA MAG.T2.48_02232 1123355.JHYO01000003_gene2881 1e-11 75.1 Methylocystaceae Bacteria 1NH69@1224,2EGPU@1,2UJXH@28211,33AFZ@2,37108@31993 NA|NA|NA MAG.T2.48_02233 1430440.MGMSRv2_3467 3e-262 911.0 Rhodospirillales nolO ko:K00612 ko00000,ko01000 Bacteria 1MWBA@1224,2JRX0@204441,2TV6G@28211,COG2192@1,COG2192@2 NA|NA|NA O Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MAG.T2.48_02235 1244869.H261_13920 1.2e-147 530.4 Rhodospirillales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4E@1224,2JQXF@204441,2TSCY@28211,COG0367@1,COG0367@2 NA|NA|NA E COG0367 Asparagine synthase (glutamine-hydrolyzing) MAG.T2.48_02236 631362.Thi970DRAFT_02812 3.1e-13 84.0 Gammaproteobacteria wbpT 2.1.1.222,2.1.1.64 ko:K00568,ko:K00754,ko:K20444 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1RB4T@1224,1SAND@1236,COG0438@1,COG0438@2,COG2227@1,COG2227@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T2.48_02237 1454007.JAUG01000036_gene4377 2.7e-12 81.3 Bacteria pel 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 Bacteria COG3866@1,COG3866@2 NA|NA|NA G Pectate lyase MAG.T2.48_02238 533247.CRD_02150 1.6e-06 60.8 Cyanobacteria Bacteria 1G060@1117,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase MAG.T2.48_02240 1244869.H261_13925 1.2e-72 280.0 Rhodospirillales Bacteria 1QU2F@1224,2JPNG@204441,2U0P8@28211,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T2.48_02242 1454007.JAUG01000036_gene4377 1.2e-12 81.6 Bacteria pel 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 Bacteria COG3866@1,COG3866@2 NA|NA|NA G Pectate lyase MAG.T2.48_02244 290318.Cvib_1452 4.5e-16 92.0 Chlorobi Bacteria 1FEQ4@1090,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain MAG.T2.48_02245 1521187.JPIM01000048_gene85 4.2e-32 144.8 Chloroflexi spsF ko:K07257 ko00000 Bacteria 2G8I7@200795,COG1861@1,COG1861@2 NA|NA|NA M Cytidylyltransferase MAG.T2.48_02246 1197906.CAJQ02000023_gene2191 4.6e-66 258.5 Alphaproteobacteria Bacteria 1Q561@1224,2UPH1@28211,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T2.48_02247 1197906.CAJQ02000023_gene2190 3.3e-105 388.7 Bradyrhizobiaceae arnB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.102,2.6.1.87,2.6.1.92 ko:K07806,ko:K13010,ko:K15895,ko:K21337 ko00520,ko00523,ko01130,ko01503,ko02020,map00520,map00523,map01130,map01503,map02020 M00721,M00761 R07659,R09825,R10460,R11467 RC00006,RC00781,RC01514,RC03445 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 iSFxv_1172.SFxv_2574 Bacteria 1MUPN@1224,2TRIQ@28211,3K65W@41294,COG0399@1,COG0399@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T2.48_02248 1173264.KI913949_gene2745 2.3e-129 468.8 Bacteria Bacteria COG0451@1,COG0451@2 NA|NA|NA GM ADP-glyceromanno-heptose 6-epimerase activity MAG.T2.48_02249 1173264.KI913949_gene2744 1.1e-26 127.1 Bacteria Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.48_02250 1380394.JADL01000007_gene4593 4.8e-73 281.6 Rhodospirillales spsE 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 R01804,R04435 RC00159 ko00000,ko00001,ko01000 Bacteria 1MWG3@1224,2JRJX@204441,2TRA6@28211,COG2089@1,COG2089@2 NA|NA|NA M COG2089 Sialic acid synthase MAG.T2.48_02251 1173264.KI913949_gene2742 7.4e-152 544.3 Oscillatoriales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1G1WZ@1117,1H9W9@1150,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T2.48_02252 1380394.JADL01000007_gene4595 2.8e-125 455.3 Alphaproteobacteria pseA 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1MVXT@1224,2U8J4@28211,COG0037@1,COG0037@2 NA|NA|NA D tRNA processing MAG.T2.48_02253 1197906.CAJQ02000023_gene2184 4.2e-30 137.5 Alphaproteobacteria Bacteria 1NZBN@1224,2F6NJ@1,2UTC1@28211,33Z52@2 NA|NA|NA MAG.T2.48_02254 1197906.CAJQ02000023_gene2183 2.7e-57 229.2 Alphaproteobacteria Bacteria 1R5UC@1224,2U711@28211,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T2.48_02255 1380394.JADL01000007_gene4608 6.9e-74 284.3 Rhodospirillales Bacteria 1RHED@1224,2JX11@204441,2UBI5@28211,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain MAG.T2.48_02256 1380394.JADL01000007_gene4609 3e-58 231.9 Alphaproteobacteria Bacteria 1NR2D@1224,2EZ5V@1,2UMRG@28211,33SBX@2 NA|NA|NA S Methyltransferase domain MAG.T2.48_02257 1197906.CAJQ02000023_gene2180 2.1e-127 463.0 Bradyrhizobiaceae asnB2 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4E@1224,2TSCY@28211,3JS0Q@41294,COG0367@1,COG0367@2 NA|NA|NA E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MAG.T2.48_02258 1122164.JHWF01000011_gene2481 9.9e-114 417.2 Legionellales Bacteria 1JEJS@118969,1MUPN@1224,1RPFX@1236,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T2.48_02259 1122164.JHWF01000011_gene2482 1.9e-77 295.8 Legionellales spsF ko:K07257 ko00000 Bacteria 1JGGB@118969,1PHID@1224,1RX64@1236,COG1861@1,COG1861@2 NA|NA|NA M Cytidylyltransferase MAG.T2.48_02260 1122164.JHWF01000011_gene2483 9.1e-56 224.2 Bacteria afr 1.1.1.292 ko:K19181 ko00000,ko01000 Bacteria COG0673@1,COG0673@2 NA|NA|NA S inositol 2-dehydrogenase activity MAG.T2.48_02261 1122164.JHWF01000011_gene2484 1.2e-19 104.4 Proteobacteria Bacteria 1NEZV@1224,COG1887@1,COG1887@2 NA|NA|NA M Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC MAG.T2.48_02262 1123229.AUBC01000004_gene3015 9.6e-29 133.7 Alphaproteobacteria Bacteria 1N9TX@1224,2USFR@28211,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T2.48_02263 1144319.PMI16_02476 1.8e-13 84.7 Proteobacteria ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1P06I@1224,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T2.48_02265 1144319.PMI16_02609 9.2e-54 217.6 Proteobacteria Bacteria 1RHBC@1224,2925F@1,2ZPQC@2 NA|NA|NA MAG.T2.48_02266 435908.IDSA_01090 5.7e-85 322.0 Idiomarinaceae ko:K02022,ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1MVJD@1224,1RQDM@1236,2QGQ0@267893,COG1132@1,COG1132@2 NA|NA|NA P ABC transporter transmembrane region MAG.T2.48_02267 1144319.PMI16_04717 4e-39 168.3 Oxalobacteraceae Bacteria 1N11Z@1224,2VWZY@28216,478WS@75682,COG1196@1,COG1196@2 NA|NA|NA H Methyltransferase FkbM domain MAG.T2.48_02268 1116472.MGMO_4c00110 1.4e-50 206.8 Gammaproteobacteria Bacteria 1RAIR@1224,1S6AX@1236,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase, family 2 MAG.T2.48_02269 1126627.BAWE01000005_gene5188 6.7e-08 64.7 Bradyrhizobiaceae 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1QSZ6@1224,2U0WV@28211,3JXTI@41294,COG0500@1,COG2226@2 NA|NA|NA Q Methionine biosynthesis protein MetW MAG.T2.48_02270 319225.Plut_1849 1.6e-31 142.9 Bacteria Bacteria COG0110@1,COG0110@2 NA|NA|NA S O-acyltransferase activity MAG.T2.48_02271 525897.Dbac_3285 8.6e-33 147.1 Desulfovibrionales Bacteria 1N6SQ@1224,2MDRS@213115,2WKVK@28221,42PE2@68525,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) MAG.T2.48_02272 1123366.TH3_00405 1.8e-33 149.1 Alphaproteobacteria Bacteria 1RABY@1224,2BWTW@1,2U5VH@28211,315N7@2 NA|NA|NA MAG.T2.48_02273 1123366.TH3_00400 1.7e-127 462.6 Rhodospirillales 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1MUPN@1224,2JR9T@204441,2TVTA@28211,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T2.48_02274 1229172.JQFA01000002_gene3175 1.6e-62 246.9 Cyanobacteria Bacteria 1G23P@1117,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T2.48_02275 272123.Anacy_0456 2.9e-19 101.7 Nostocales vapC Bacteria 1GKNT@1117,1HSMZ@1161,COG4113@1,COG4113@2 NA|NA|NA S PIN domain MAG.T2.48_02279 443598.AUFA01000133_gene3465 5.2e-08 64.3 Bradyrhizobiaceae Bacteria 1MXYG@1224,2TTWJ@28211,3JUQG@41294,COG3385@1,COG3385@2 NA|NA|NA L Transposase IS4 family MAG.T2.48_02280 1197906.CAJQ02000023_gene2174 1.1e-41 177.2 Alphaproteobacteria Bacteria 1N14A@1224,2TXMR@28211,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T2.48_02281 1197906.CAJQ02000023_gene2173 1.9e-69 269.2 Bradyrhizobiaceae Bacteria 1RF23@1224,2UH95@28211,3K4GS@41294,COG0500@1,COG2226@2 NA|NA|NA Q Caenorhabditis protein of unknown function, DUF268 MAG.T2.48_02282 32057.KB217478_gene3290 2.7e-57 228.8 Nostocales Bacteria 1GK4A@1117,1HQAZ@1161,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T2.48_02283 1305735.JAFT01000005_gene3792 1.2e-29 137.1 Alphaproteobacteria Bacteria 1RD8N@1224,2U07K@28211,2ZC3Y@2,arCOG09486@1 NA|NA|NA S N-acetyllactosaminide 3-alpha-galactosyltransferase activity MAG.T2.48_02284 1144342.PMI40_03440 2.6e-40 172.6 Oxalobacteraceae Bacteria 1QVAX@1224,2WH3H@28216,4750G@75682,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase, family 2 MAG.T2.48_02285 314345.SPV1_00240 4.9e-77 295.0 Proteobacteria capM Bacteria 1N0DG@1224,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase group 1 MAG.T2.48_02286 187272.Mlg_0802 4.3e-147 528.5 Chromatiales wbpM 4.2.1.115 ko:K15894 ko00520,map00520 R09697 RC02609 ko00000,ko00001,ko01000 Bacteria 1MWKY@1224,1RNQ2@1236,1WW39@135613,COG1086@1,COG1086@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T2.48_02287 1120956.JHZK01000009_gene1693 8.4e-07 62.4 Alphaproteobacteria Bacteria 1N3Q5@1224,2ANRX@1,2UCSQ@28211,31DRT@2 NA|NA|NA MAG.T2.48_02288 1121861.KB899911_gene1188 3.8e-61 242.7 Rhodospirillales ko:K00754 ko00000,ko01000 GT4 Bacteria 1RB4T@1224,2JUWG@204441,2UD9U@28211,COG0438@1,COG0438@2,COG4122@1,COG4122@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T2.48_02289 1216976.AX27061_5922 4.5e-53 214.9 Alcaligenaceae wzm ko:K01992,ko:K09690,ko:K09691,ko:K09692 ko02010,map02010 M00250,M00251,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103,3.A.1.104 Bacteria 1N0X3@1224,2VHT7@28216,3T4TU@506,COG1682@1,COG1682@2 NA|NA|NA U ABC-2 type transporter MAG.T2.48_02290 1121861.KB899911_gene1190 9.4e-83 314.3 Rhodospirillales 3.6.3.38 ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.103 Bacteria 1MWWC@1224,2JQDY@204441,2TU3M@28211,COG1134@1,COG1134@2 NA|NA|NA GM ATPases associated with a variety of cellular activities MAG.T2.48_02291 925409.KI911562_gene150 5.9e-39 168.3 Bacteroidetes Bacteria 4NNQC@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T2.48_02292 1454007.JAUG01000036_gene4377 1.9e-13 82.4 Bacteria pel 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 Bacteria COG3866@1,COG3866@2 NA|NA|NA G Pectate lyase MAG.T2.48_02293 1121861.KB899911_gene1186 4.8e-149 535.0 Rhodospirillales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4E@1224,2JQXF@204441,2TSCY@28211,COG0367@1,COG0367@2 NA|NA|NA E COG0367 Asparagine synthase (glutamine-hydrolyzing) MAG.T2.48_02294 1121935.AQXX01000121_gene5560 6.7e-139 500.4 Oceanospirillales capI 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 R01385 RC00289 ko00000,ko00001,ko01000 Bacteria 1MU7J@1224,1RPTA@1236,1XIBG@135619,COG0451@1,COG0451@2 NA|NA|NA M Polysaccharide biosynthesis protein MAG.T2.48_02295 631362.Thi970DRAFT_02821 1.1e-143 516.9 Gammaproteobacteria Bacteria 1QR54@1224,1SMRM@1236,COG0500@1,COG1215@1,COG1215@2,COG2226@2 NA|NA|NA MQ Glycosyltransferase like family 2 MAG.T2.48_02296 1026882.MAMP_01113 5.8e-142 510.8 Thiotrichales fic Bacteria 1MV69@1224,1RM9J@1236,461RV@72273,COG3177@1,COG3177@2 NA|NA|NA S Domain of unknown function (DUF4172) MAG.T2.48_02297 631362.Thi970DRAFT_02815 2e-11 77.8 Bacteria Bacteria 2EWXB@1,33Q8Q@2 NA|NA|NA MAG.T2.48_02298 323261.Noc_2479 2.9e-61 242.7 Chromatiales wbpT ko:K13003 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1MU9C@1224,1RRWX@1236,1WYF9@135613,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 MAG.T2.48_02299 1173027.Mic7113_5255 3.2e-209 734.9 Oscillatoriales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1G1WZ@1117,1H9W9@1150,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T2.48_02300 1269813.ATUL01000048_gene2591 3.1e-77 295.8 Chromatiales 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1N0DG@1224,1S0D6@1236,1X0R1@135613,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like MAG.T2.48_02301 1232683.ADIMK_1478 8.8e-83 314.3 Alteromonadaceae wcaJ GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 ko:K05946,ko:K21303 ko05111,map05111 ko00000,ko00001,ko01000,ko01003,ko01005 GT26 Bacteria 1MV6W@1224,1RMMN@1236,464MI@72275,COG2148@1,COG2148@2 NA|NA|NA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis MAG.T2.48_02304 1379270.AUXF01000006_gene9 4e-10 72.4 Gemmatimonadetes yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1ZU16@142182,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family MAG.T2.48_02305 1142394.PSMK_24810 6.8e-55 221.1 Planctomycetes pphA GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009266,GO:0009628,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:0140096,GO:1901564 3.1.3.16 ko:K07313,ko:K07314 ko00000,ko01000 Bacteria 2IZ5T@203682,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase MAG.T2.48_02307 452637.Oter_0261 9.3e-18 97.8 Verrucomicrobia Bacteria 2ECN9@1,336K5@2,46T7K@74201 NA|NA|NA MAG.T2.48_02319 316274.Haur_1335 4.5e-23 116.3 Chloroflexia Bacteria 2G8NQ@200795,37611@32061,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease MAG.T2.48_02321 1142394.PSMK_24160 1.6e-191 676.8 Planctomycetes ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2IXHF@203682,COG1674@1,COG1674@2 NA|NA|NA D COG1674 DNA segregation ATPase FtsK SpoIIIE and related MAG.T2.48_02322 1123242.JH636436_gene228 1.6e-19 102.4 Planctomycetes 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2J09I@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) MAG.T2.48_02323 1142394.PSMK_24110 5.6e-28 130.6 Planctomycetes acpP 2.7.9.2 ko:K01007,ko:K02078 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2J04I@203682,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T2.48_02324 1142394.PSMK_24100 2.1e-32 145.6 Planctomycetes 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IZWX@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) MAG.T2.48_02325 1123255.JHYS01000016_gene1091 1.2e-17 99.0 Comamonadaceae 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R14N@1224,2WHZ9@28216,4AIB3@80864,COG2340@1,COG2340@2,COG3055@1,COG3055@2,COG4447@1,COG4447@2 NA|NA|NA S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.48_02326 530564.Psta_4579 3.4e-88 332.4 Planctomycetes Bacteria 2IXDR@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.48_02328 1142394.PSMK_27470 1.3e-85 323.6 Planctomycetes dus Bacteria 2IYH0@203682,COG0042@1,COG0042@2 NA|NA|NA H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T2.48_02329 1192034.CAP_8277 4.5e-38 166.0 Myxococcales ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1QZBM@1224,2WQPM@28221,2Z3I2@29,42TG7@68525,COG3266@1,COG3266@2 NA|NA|NA S FG-GAP repeat MAG.T2.48_02330 686340.Metal_0726 4.5e-63 248.1 Methylococcales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1NKIB@1224,1S1VI@1236,1XESX@135618,COG0412@1,COG0412@2 NA|NA|NA Q PFAM Dienelactone hydrolase MAG.T2.48_02331 768671.ThimaDRAFT_0622 1.2e-56 228.0 Chromatiales glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1MU8H@1224,1RQWX@1236,1WZGU@135613,COG0584@1,COG0584@2 NA|NA|NA C PFAM Glycerophosphoryl diester phosphodiesterase MAG.T2.48_02334 1142394.PSMK_14250 5.1e-176 625.2 Planctomycetes rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2IX1J@203682,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs MAG.T2.48_02335 713587.THITH_05240 4.1e-50 205.3 Gammaproteobacteria Bacteria 1R7GE@1224,1S7TF@1236,28JZ9@1,2Z9PC@2 NA|NA|NA MAG.T2.48_02336 1123508.JH636441_gene3292 1.6e-26 125.6 Bacteria Bacteria 2E71G@1,331K5@2 NA|NA|NA MAG.T2.48_02337 1382359.JIAL01000001_gene270 1.9e-104 386.3 Bacteria ko:K07133 ko00000 Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily MAG.T2.48_02338 344747.PM8797T_15181 1.2e-10 73.6 Planctomycetes Bacteria 2J0TW@203682,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family MAG.T2.48_02339 1336245.JAGO01000003_gene595 2.6e-16 92.4 Oceanospirillales grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1RH8T@1224,1S5W5@1236,1XK1E@135619,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MAG.T2.48_02340 1142394.PSMK_19850 6.5e-98 364.4 Planctomycetes dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 2IXQJ@203682,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T2.48_02341 1142394.PSMK_19840 2e-201 708.8 Planctomycetes groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2IXJW@203682,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T2.48_02342 247490.KSU1_B0245 4.9e-26 123.6 Planctomycetes groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2J0E5@203682,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T2.48_02343 1142394.PSMK_19820 4.1e-205 721.1 Planctomycetes groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2IWZS@203682,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T2.48_02344 398525.KB900701_gene7366 5.8e-49 201.1 Bradyrhizobiaceae Bacteria 1REJ2@1224,2U7T5@28211,3JV3K@41294,COG0500@1,COG0500@2 NA|NA|NA Q Nodulation protein S (NodS) MAG.T2.48_02346 1142394.PSMK_20470 7.1e-95 354.0 Planctomycetes moxR ko:K03924 ko00000,ko01000 Bacteria 2IYBI@203682,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T2.48_02347 391589.RGAI101_2817 4.6e-28 132.9 Roseobacter Bacteria 1PVZJ@1224,2P1NV@2433,2TRAB@28211,COG0739@1,COG0739@2 NA|NA|NA M COG0739 Membrane proteins related to metalloendopeptidases MAG.T2.48_02350 1430440.MGMSRv2_3614 4.9e-70 271.2 Rhodospirillales queC 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 R09978 RC00959 ko00000,ko00001,ko01000,ko03016 iAF987.Gmet_3075 Bacteria 1MU5V@1224,2JTE6@204441,2TU7F@28211,COG0603@1,COG0603@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) MAG.T2.48_02353 1142394.PSMK_21320 3.2e-233 815.1 Planctomycetes gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2IXF8@203682,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T2.48_02354 1142394.PSMK_04940 2e-34 152.9 Bacteria 3.5.1.28 ko:K01448,ko:K07273 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria COG5632@1,COG5632@2 NA|NA|NA M N-Acetylmuramoyl-L-alanine amidase MAG.T2.48_02355 383372.Rcas_2774 9.1e-25 120.9 Chloroflexia nucH ko:K07004 ko00000 Bacteria 2G82K@200795,374Y1@32061,COG2374@1,COG2374@2,COG3391@1,COG3391@2 NA|NA|NA S PFAM Endonuclease exonuclease phosphatase MAG.T2.48_02356 926569.ANT_24910 5.4e-148 531.2 Chloroflexi xylB 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2G5QX@200795,COG1070@1,COG1070@2 NA|NA|NA G PFAM carbohydrate kinase MAG.T2.48_02357 44056.XP_009034826.1 5.2e-17 95.9 Eukaryota Eukaryota 2E3BA@1,2SAF2@2759 NA|NA|NA S FG-GAP repeat MAG.T2.48_02359 1123508.JH636449_gene7344 2.6e-47 196.1 Planctomycetes 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2IZQ7@203682,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family MAG.T2.48_02360 1396141.BATP01000023_gene662 1.1e-14 87.0 Verrucomicrobiae Bacteria 2EANR@1,2IURH@203494,334R8@2,46W9X@74201 NA|NA|NA MAG.T2.48_02361 1396418.BATQ01000151_gene2360 4.1e-71 275.4 Verrucomicrobiae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2ITTN@203494,46UTH@74201,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T2.48_02362 240016.ABIZ01000001_gene1316 1.5e-78 300.1 Verrucomicrobiae ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 2IU3C@203494,46UT4@74201,COG4591@1,COG4591@2 NA|NA|NA M MacB-like periplasmic core domain MAG.T2.48_02363 1403819.BATR01000083_gene2432 3.9e-74 284.6 Verrucomicrobiae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2ITZH@203494,46UUF@74201,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T2.48_02364 1396141.BATP01000023_gene658 1.9e-36 160.6 Verrucomicrobiae ko:K02005 ko00000 Bacteria 2ITKT@203494,46U7W@74201,COG0845@1,COG0845@2 NA|NA|NA M HlyD family secretion protein MAG.T2.48_02366 1265502.KB905931_gene1749 1.8e-87 330.1 Comamonadaceae rmuC ko:K09760 ko00000 Bacteria 1MWHV@1224,2VJVZ@28216,4AATV@80864,COG1322@1,COG1322@2 NA|NA|NA S RmuC family MAG.T2.48_02367 521674.Plim_3896 4.1e-42 179.1 Planctomycetes yobV5 ko:K13572 ko00000,ko03051 Bacteria 2IZQB@203682,COG2378@1,COG2378@2 NA|NA|NA K WYL domain MAG.T2.48_02368 102129.Lepto7375DRAFT_0845 5.5e-16 92.0 Bacteria Bacteria COG1572@1,COG1572@2,COG3209@1,COG3209@2 NA|NA|NA NU bacterial-type flagellum-dependent cell motility MAG.T2.48_02369 118168.MC7420_8161 3.9e-63 248.1 Oscillatoriales 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1G67K@1117,1HC0C@1150,COG0572@1,COG0572@2 NA|NA|NA F uridine kinase MAG.T2.48_02370 690850.Desaf_2163 2.6e-15 88.6 Bacteria ko:K03892 ko00000,ko03000 Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity MAG.T2.48_02371 641491.DND132_1319 4.4e-46 191.8 Desulfovibrionales arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1MWYQ@1224,2MBFG@213115,2WNEC@28221,42RQI@68525,COG0394@1,COG0394@2 NA|NA|NA T PFAM Protein-tyrosine phosphatase, low molecular weight MAG.T2.48_02372 535289.Dtpsy_2139 3.4e-181 641.7 Comamonadaceae arsA 3.6.3.16 ko:K01551 ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 Bacteria 1MUTX@1224,2VK65@28216,4AD7R@80864,COG0003@1,COG0003@2 NA|NA|NA P TIGRFAM arsenite-activated ATPase ArsA MAG.T2.48_02373 290397.Adeh_1023 6.6e-132 477.2 Myxococcales arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 ko:K03325,ko:K03741 ko00000,ko01000,ko02000 2.A.59 iYO844.BSU25790 Bacteria 1MUXY@1224,2WK36@28221,2Z0TJ@29,42M0Z@68525,COG0798@1,COG0798@2 NA|NA|NA P arsenical-resistance protein MAG.T2.48_02374 261292.Nit79A3_2553 4.4e-14 85.1 Bacteria Bacteria 2AZY1@1,31S7T@2 NA|NA|NA MAG.T2.48_02377 1219065.VPR01S_04_00040 1.1e-09 70.1 Vibrionales sprT ko:K02742 ko00000 Bacteria 1RJW4@1224,1S70F@1236,1XW7P@135623,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family MAG.T2.48_02378 1038867.AXAY01000023_gene4630 4.6e-173 614.8 Bradyrhizobiaceae maeA 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU0A@1224,2TQJT@28211,3JT6H@41294,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain MAG.T2.48_02379 1485544.JQKP01000016_gene673 8e-160 570.9 Nitrosomonadales zntA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1MU08@1224,2VJBP@28216,44W7D@713636,COG2217@1,COG2217@2,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain MAG.T2.48_02380 497965.Cyan7822_3710 1.5e-54 219.5 Cyanothece coaBC 4.1.1.36,6.3.2.5 ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1G2DG@1117,3KG6V@43988,COG0452@1,COG0452@2 NA|NA|NA H TIGRFAM phosphopantothenoylcysteine decarboxylase phosphopantothenate cysteine ligase MAG.T2.48_02381 1192034.CAP_8278 6.8e-17 95.5 Myxococcales Bacteria 1R0E4@1224,2X84M@28221,2YUU3@29,43EEC@68525,COG1520@1,COG1520@2 NA|NA|NA S FG-GAP repeat MAG.T2.48_02383 243233.MCA1674 4.3e-68 266.2 Methylococcales wspA ko:K03406,ko:K13487 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,1S0J1@1236,1XGYS@135618,COG0840@1,COG0840@2 NA|NA|NA NT similarity to SP P39216 MAG.T2.48_02384 1267533.KB906733_gene3472 2e-60 240.7 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_02385 414684.RC1_0281 0.0 1181.4 Rhodospirillales acrB ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 Bacteria 1MU48@1224,2JPRP@204441,2TQT0@28211,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.48_02386 414684.RC1_0280 1.3e-46 194.1 Rhodospirillales ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MUFW@1224,2JQ7V@204441,2U2CU@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_02387 1403819.BATR01000124_gene4378 9.4e-40 170.2 Verrucomicrobiae Bacteria 2IV3S@203494,46X9E@74201,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T2.48_02388 314230.DSM3645_24020 8.9e-65 254.6 Planctomycetes ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IYHA@203682,COG1459@1,COG1459@2 NA|NA|NA U Type II secretion system (T2SS), protein F MAG.T2.48_02389 530564.Psta_3638 5.9e-138 498.0 Planctomycetes pulE ko:K02652 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX4I@203682,COG2804@1,COG2804@2 NA|NA|NA NU COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB MAG.T2.48_02399 1142394.PSMK_14360 1.2e-110 407.5 Planctomycetes ko:K02453,ko:K02666 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IY1C@203682,COG4796@1,COG4796@2 NA|NA|NA U Belongs to the GSP D family MAG.T2.48_02400 1121101.HMPREF1532_02977 6.9e-07 62.0 Bacteroidaceae ko:K09973 ko00000 Bacteria 2FMV8@200643,4AP60@815,4NJVP@976,COG0265@1,COG0265@2,COG0457@1,COG0457@2 NA|NA|NA O COG COG0457 FOG TPR repeat MAG.T2.48_02401 631454.N177_2768 9.5e-109 400.2 Rhodobiaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1JNMB@119043,1MU2D@1224,2TSM8@28211,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase MAG.T2.48_02403 497964.CfE428DRAFT_6342 1.1e-168 600.5 Verrucomicrobia Bacteria 46TMJ@74201,COG3064@1,COG3064@2 NA|NA|NA M Peptidase M60-like family MAG.T2.48_02405 497964.CfE428DRAFT_0572 2.9e-62 246.5 Verrucomicrobia Bacteria 46T3U@74201,COG3488@1,COG3488@2 NA|NA|NA C Di-haem oxidoreductase, putative peroxidase MAG.T2.48_02406 1122176.KB903531_gene2955 1.8e-20 108.2 Sphingobacteriia Bacteria 1IYS6@117747,4NDUD@976,COG5276@1,COG5276@2 NA|NA|NA S cellulase activity MAG.T2.48_02407 880072.Desac_1403 3.6e-56 225.7 Syntrophobacterales mdtA ko:K07799,ko:K21135 ko02020,map02020 M00648,M00822 ko00000,ko00001,ko00002,ko02000 2.A.6.2.35,8.A.1 Bacteria 1MW65@1224,2MR7H@213462,2WJ8R@28221,42NJG@68525,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_02408 883.DvMF_1515 0.0 1087.4 Desulfovibrionales ko:K03296 ko00000 2.A.6.2 Bacteria 1MU48@1224,2M7S1@213115,2WJ8D@28221,42MF6@68525,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.48_02411 661478.OP10G_0834 6.5e-115 421.0 Bacteria Bacteria COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine MAG.T2.48_02412 1255043.TVNIR_3073 4.1e-61 242.3 Gammaproteobacteria Bacteria 1NT1Q@1224,1RP9M@1236,COG1752@1,COG1752@2 NA|NA|NA S esterase of the alpha-beta hydrolase superfamily MAG.T2.48_02413 43989.cce_3872 3.7e-12 79.7 Cyanothece Bacteria 1GQ6G@1117,3KGFS@43988,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T2.48_02415 1211777.BN77_2526 0.0 1442.2 Rhizobiaceae 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2TTXG@28211,4B9AV@82115,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T2.48_02416 1123392.AQWL01000003_gene237 3.7e-37 162.5 Betaproteobacteria Bacteria 1REUR@1224,29MQ2@1,2VXQA@28216,308MT@2 NA|NA|NA MAG.T2.48_02417 706587.Desti_2495 2.4e-40 172.9 Bacteria Bacteria COG3631@1,COG3631@2 NA|NA|NA S light absorption MAG.T2.48_02420 558152.IQ37_02140 2.7e-29 136.0 Chryseobacterium Bacteria 1I4J7@117743,2B9NZ@1,3231D@2,3ZUFF@59732,4NR0T@976 NA|NA|NA S Protein of unknown function (DUF1579) MAG.T2.48_02421 1396141.BATP01000061_gene4533 2.9e-19 101.7 Verrucomicrobiae Bacteria 2IWEU@203494,46XRB@74201,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix MAG.T2.48_02424 903818.KI912268_gene3327 1.7e-69 270.0 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T2.48_02425 96561.Dole_1787 1e-08 68.9 Desulfobacterales 3.2.1.81 ko:K01219,ko:K03749,ko:K15725 ko00000,ko01000,ko02000 1.B.17.2.2 Bacteria 1N4S6@1224,2MNRP@213118,2X729@28221,43BRE@68525,COG1653@1,COG1653@2,COG3210@1,COG3210@2,COG3266@1,COG3266@2,COG5492@1,COG5492@2 NA|NA|NA G domain protein MAG.T2.48_02426 1142394.PSMK_04560 3.3e-267 927.9 Planctomycetes gyrA 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2IY0U@203682,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T2.48_02431 1210884.HG799475_gene15231 2.6e-48 199.1 Planctomycetes surE 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2IXPI@203682,COG0496@1,COG0496@2 NA|NA|NA S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates MAG.T2.48_02432 575540.Isop_2075 7.4e-47 194.9 Planctomycetes Bacteria 2J02Q@203682,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T2.48_02433 526218.Sterm_3823 5.6e-33 147.9 Fusobacteria nnrD 3.6.3.34,4.2.1.136,5.1.99.6 ko:K02013,ko:K17758,ko:K17759 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 37A3S@32066,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T2.48_02434 415426.Hbut_0490 1e-30 140.6 Crenarchaeota pebP ko:K06910,ko:K07032 ko00000 Archaea 2XQN7@28889,COG1881@1,arCOG04702@2157 NA|NA|NA S PFAM PEBP family protein MAG.T2.48_02435 1142394.PSMK_12440 1.5e-50 207.6 Planctomycetes lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 ko:K02004,ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125,3.A.1.15.3,3.A.1.15.5 Bacteria 2IY15@203682,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component MAG.T2.48_02436 530564.Psta_0644 7.9e-57 227.3 Planctomycetes lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 2IYZ3@203682,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner MAG.T2.48_02437 118005.AWNK01000006_gene1234 6.6e-137 494.6 Bacteria 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria COG0475@1,COG0475@2,COG1762@1,COG1762@2 NA|NA|NA P glutathione-regulated potassium exporter activity MAG.T2.48_02438 344747.PM8797T_14961 2.4e-28 133.7 Planctomycetes Bacteria 2FEU1@1,2J3WI@203682,346SY@2 NA|NA|NA MAG.T2.48_02439 1142394.PSMK_03880 0.0 1256.1 Planctomycetes clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2IXHI@203682,COG0542@1,COG0542@2 NA|NA|NA O with chaperone activity ATP-binding MAG.T2.48_02441 1142394.PSMK_22770 4e-165 588.2 Planctomycetes nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 Bacteria 2IY30@203682,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate MAG.T2.48_02442 756272.Plabr_3518 1.4e-28 134.4 Planctomycetes tolB ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 2IX8E@203682,COG0265@1,COG0265@2,COG0823@1,COG0823@2,COG2234@1,COG2234@2 NA|NA|NA O PA domain MAG.T2.48_02443 314230.DSM3645_11956 5.7e-48 198.0 Planctomycetes rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.28,5.4.99.29 ko:K06177 ko00000,ko01000,ko03009,ko03016 Bacteria 2J30R@203682,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T2.48_02444 575540.Isop_2285 1.7e-157 563.1 Planctomycetes shc 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IXWT@203682,COG1657@1,COG1657@2 NA|NA|NA I COG1657 Squalene cyclase MAG.T2.48_02446 1142394.PSMK_06840 9.6e-129 466.8 Planctomycetes 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2IWTD@203682,COG0673@1,COG0673@2 NA|NA|NA S PFAM oxidoreductase MAG.T2.48_02449 1210884.HG799462_gene7967 5.6e-59 234.2 Planctomycetes trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYUN@203682,COG0512@1,COG0512@2 NA|NA|NA EH TIGRFAM glutamine amidotransferase of anthranilate synthase MAG.T2.48_02450 383372.Rcas_1796 1e-17 97.4 Chloroflexia ytpQ Bacteria 2GAD2@200795,375H8@32061,COG4848@1,COG4848@2 NA|NA|NA S Protein of unknown function (DUF1444) MAG.T2.48_02451 1142394.PSMK_16120 1.7e-71 276.2 Planctomycetes kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IXME@203682,COG2877@1,COG2877@2 NA|NA|NA M 8-phosphate synthase MAG.T2.48_02452 1142394.PSMK_26150 5.5e-29 134.4 Planctomycetes CP_0046 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 2J09E@203682,COG3880@1,COG3880@2 NA|NA|NA S protein with conserved CXXC pairs MAG.T2.48_02453 1142394.PSMK_26160 8.4e-76 290.8 Planctomycetes mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1,2.7.3.2,2.7.3.3 ko:K00933,ko:K00934,ko:K19405 ko00330,ko01100,map00330,map01100 M00047 R00554,R01881,R11090 RC00002,RC00203 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IXJG@203682,COG3869@1,COG3869@2 NA|NA|NA H Catalyzes the specific phosphorylation of arginine residues in proteins MAG.T2.48_02454 1382359.JIAL01000001_gene2698 1.8e-20 105.1 Acidobacteriia phhB 3.5.4.33,4.2.1.96 ko:K01724,ko:K11991 ko00790,map00790 R04734,R10223 RC00477,RC01208 ko00000,ko00001,ko01000,ko03016,ko04147 Bacteria 2JNDN@204432,3Y5UG@57723,COG2154@1,COG2154@2 NA|NA|NA H Pterin 4 alpha carbinolamine dehydratase MAG.T2.48_02455 1298863.AUEP01000012_gene3742 2.2e-44 185.7 Propionibacteriales ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 2GKC5@201174,4DQ6E@85009,COG0307@1,COG0307@2 NA|NA|NA H riboflavin synthase, alpha MAG.T2.48_02456 1142394.PSMK_31540 2.4e-39 170.2 Planctomycetes ko:K06381 ko00000 Bacteria 2J08W@203682,COG2385@1,COG2385@2 NA|NA|NA D Stage II sporulation protein MAG.T2.48_02457 1142394.PSMK_16480 1.7e-75 289.7 Planctomycetes rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXMK@203682,COG0202@1,COG0202@2,COG0457@1,COG0457@2 NA|NA|NA K rna polymerase alpha MAG.T2.48_02458 690850.Desaf_1546 3.3e-54 219.5 Desulfovibrionales norM-2 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 1MUAM@1224,2M98N@213115,2WM16@28221,42MX0@68525,COG0534@1,COG0534@2 NA|NA|NA V PFAM Multi antimicrobial extrusion protein MatE MAG.T2.48_02459 1242864.D187_006688 2.2e-28 131.7 Deltaproteobacteria sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 1MZ6P@1224,2WQK6@28221,42TM1@68525,COG2076@1,COG2076@2 NA|NA|NA P PFAM small multidrug resistance protein MAG.T2.48_02460 863365.XHC_4065 2.4e-18 100.1 Xanthomonadales Bacteria 1MY4C@1224,1SETF@1236,1X3XM@135614,COG1073@1,COG1073@2 NA|NA|NA S Alpha beta MAG.T2.48_02461 761193.Runsl_2577 6.8e-25 120.6 Cytophagia Bacteria 2CHCP@1,32S5R@2,47RF4@768503,4NS9G@976 NA|NA|NA S Domain of unknown function (DU1801) MAG.T2.48_02463 1472716.KBK24_0123485 5.6e-27 129.0 Burkholderiaceae ko:K19123 ko00000,ko02048 Bacteria 1K5MV@119060,1RFMJ@1224,2W2GG@28216,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.48_02464 360094.PXO_03125 7.6e-09 68.9 Xanthomonadales ybjY ko:K02005 ko00000 Bacteria 1NQDN@1224,1RRFE@1236,1X3QX@135614,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.48_02465 349741.Amuc_1059 1.3e-215 756.9 Verrucomicrobiae czcA ko:K07239,ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1,2.A.6.1.4 Bacteria 2ITM5@203494,46USJ@74201,COG3696@1,COG3696@2 NA|NA|NA P AcrB/AcrD/AcrF family MAG.T2.48_02467 493475.GARC_5284 2.4e-75 290.0 Alteromonadaceae ko:K02660 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko02035,ko02044 Bacteria 1MV70@1224,1RPPQ@1236,465BG@72275,COG1858@1,COG1858@2 NA|NA|NA P Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.48_02468 1071679.BG57_05105 9.1e-61 240.4 Burkholderiaceae cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1K68T@119060,1QX11@1224,2VSEU@28216,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T2.48_02469 1304275.C41B8_09896 7.8e-50 203.8 Gammaproteobacteria tdsD Bacteria 1RA6E@1224,1S460@1236,COG0778@1,COG0778@2 NA|NA|NA C Pfam Nitroreductase MAG.T2.48_02470 1142394.PSMK_23470 4.4e-167 594.7 Planctomycetes nuoG 1.6.5.3 ko:K00184,ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,5.A.3 Bacteria 2IY04@203682,COG0243@1,COG0243@2,COG1034@1,COG1034@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region MAG.T2.48_02472 1142394.PSMK_03120 1.5e-141 509.6 Planctomycetes 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IX8X@203682,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T2.48_02473 1142394.PSMK_03130 4.3e-93 348.6 Planctomycetes 2.3.1.179,2.3.1.235,2.3.1.260 ko:K05551,ko:K09458 ko00061,ko00253,ko00780,ko01056,ko01100,ko01130,ko01212,map00061,map00253,map00780,map01056,map01100,map01130,map01212 M00083,M00572,M00778 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R06635,R06637,R06641,R06643,R06644,R06645,R07762,R09258,R09259,R10115,R10119,R10960,R11516 RC00004,RC00039,RC02545,RC02728,RC02729,RC02888,RC02931,RC02932,RC02947 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Bacteria 2IY1N@203682,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T2.48_02475 864051.BurJ1DRAFT_1887 1.3e-34 152.1 unclassified Burkholderiales ko:K09803 ko00000 Bacteria 1KP5J@119065,1N6QP@1224,2WAXH@28216,COG2929@1,COG2929@2 NA|NA|NA S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system MAG.T2.48_02476 864051.BurJ1DRAFT_1886 4.3e-30 136.7 Proteobacteria Bacteria 1NAV1@1224,COG3514@1,COG3514@2 NA|NA|NA S BrnA antitoxin of type II toxin-antitoxin system MAG.T2.48_02479 1205753.A989_13474 4.8e-167 594.3 Xanthomonadales dhs1 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUWF@1224,1RRMM@1236,1X2YX@135614,COG3200@1,COG3200@2 NA|NA|NA E phospho-2-dehydro-3-deoxyheptonate aldolase MAG.T2.48_02481 391600.ABRU01000050_gene159 5.7e-07 61.6 Proteobacteria ko:K15977 ko00000 Bacteria 1N1TY@1224,COG2259@1,COG2259@2 NA|NA|NA S DoxX MAG.T2.48_02482 1142394.PSMK_00360 1e-20 107.8 Bacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria COG2304@1,COG2304@2 NA|NA|NA IU oxidoreductase activity MAG.T2.48_02483 1142394.PSMK_00340 3e-37 162.2 Planctomycetes ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IYYI@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA TolQ ExbB proton channel MAG.T2.48_02485 1142394.PSMK_00320 6.7e-08 64.7 Bacteria exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria COG0848@1,COG0848@2 NA|NA|NA U biopolymer transport protein MAG.T2.48_02487 1089550.ATTH01000001_gene1987 7.5e-46 192.2 Bacteroidetes Bacteria 4NKIR@976,COG2866@1,COG2866@2,COG2931@1,COG2931@2,COG3291@1,COG3291@2 NA|NA|NA Q SMART Integrin alpha beta-propellor repeat protein MAG.T2.48_02488 443143.GM18_3755 1.4e-22 113.2 Deltaproteobacteria mqnB GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.4.2.1,3.2.2.26,3.2.2.9 ko:K01243,ko:K03784,ko:K11783 ko00130,ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,ko01230,map00130,map00230,map00240,map00270,map00760,map01100,map01110,map01230 M00034,M00609 R00194,R01401,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R08587,R10244 RC00033,RC00063,RC00122,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1NDXU@1224,2WQX3@28221,42TU4@68525,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.48_02489 1142394.PSMK_07030 3.6e-111 408.7 Planctomycetes hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IY1U@203682,COG0124@1,COG0124@2 NA|NA|NA J tRNA synthetase class II MAG.T2.48_02491 1122223.KB890696_gene428 1e-176 626.7 Deinococcus-Thermus icmA 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 1WIX7@1297,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase MAG.T2.48_02494 1396418.BATQ01000016_gene4273 2.6e-52 212.6 Verrucomicrobiae Bacteria 2IVMP@203494,46T3I@74201,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T2.48_02496 1238182.C882_1217 4.4e-310 1070.8 Rhodospirillales metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV6G@1224,2JQ1S@204441,2TQTG@28211,COG0646@1,COG0646@2,COG1410@1,COG1410@2 NA|NA|NA E Methionine synthase MAG.T2.48_02499 575540.Isop_1666 2.9e-75 289.7 Bacteria 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.48_02500 379066.GAU_1101 6e-27 128.6 Gemmatimonadetes lolA ko:K03634 ko00000 Bacteria 1ZUW4@142182,COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) MAG.T2.48_02501 1234364.AMSF01000024_gene3768 6.9e-64 251.1 Xanthomonadales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1QUPV@1224,1T47Q@1236,1XD8K@135614,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter MAG.T2.48_02502 448385.sce9075 2.4e-35 156.8 Proteobacteria natB ko:K01992,ko:K09696 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.115 Bacteria 1R62N@1224,COG1668@1,COG1668@2 NA|NA|NA CP COG1668 ABC-type Na efflux pump, permease component MAG.T2.48_02504 429009.Adeg_0187 3.5e-31 141.7 Thermoanaerobacterales hit GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 Bacteria 1V5CH@1239,24HFR@186801,42IAH@68295,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding MAG.T2.48_02506 1142394.PSMK_28130 3e-54 219.5 Bacteria Bacteria 2DRTQ@1,32URN@2 NA|NA|NA MAG.T2.48_02507 1142394.PSMK_26660 1.4e-219 769.2 Planctomycetes rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 Bacteria 2IXPK@203682,COG0539@1,COG0539@2,COG2183@1,COG2183@2 NA|NA|NA J Ribosomal protein S1 MAG.T2.48_02509 1142394.PSMK_11750 2e-08 67.0 Planctomycetes ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2IY62@203682,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Belongs to the GSP D family MAG.T2.48_02510 756272.Plabr_0265 1.4e-71 277.3 Planctomycetes ko:K08218,ko:K08223 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25,2.A.1.35 Bacteria 2IY9C@203682,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator Superfamily MAG.T2.48_02511 991905.SL003B_1325 9.5e-16 92.0 Proteobacteria Bacteria 1R9UF@1224,COG5305@1,COG5305@2 NA|NA|NA S membrane MAG.T2.48_02512 1142394.PSMK_10550 1.6e-72 280.8 Planctomycetes ragB 2.7.13.3 ko:K02484,ko:K03406,ko:K07638,ko:K07639,ko:K07640,ko:K07641,ko:K07642,ko:K07644,ko:K07650,ko:K07653,ko:K07654,ko:K07711,ko:K10819,ko:K14980,ko:K18072,ko:K18143,ko:K18345,ko:K18351,ko:K19609,ko:K20487 ko01501,ko01502,ko01503,ko02020,ko02024,ko02026,ko02030,map01501,map01502,map01503,map02020,map02024,map02026,map02030 M00445,M00446,M00447,M00448,M00449,M00450,M00452,M00460,M00461,M00502,M00520,M00645,M00646,M00648,M00649,M00651,M00654,M00655,M00656,M00658,M00721,M00727,M00728,M00742,M00743,M00745,M00770,M00816 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022,ko02035 Bacteria 2IXA1@203682,COG0642@1,COG2205@2,COG2770@1,COG2770@2 NA|NA|NA T PhoQ Sensor MAG.T2.48_02513 290317.Cpha266_0257 1e-120 439.9 Chlorobi int ko:K04763 ko00000,ko03036 Bacteria 1FESB@1090,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.48_02515 671143.DAMO_1287 1.8e-143 515.8 unclassified Bacteria ko:K07497 ko00000 Bacteria 2NQ4I@2323,COG2801@1,COG2801@2 NA|NA|NA L Homeodomain-like domain MAG.T2.48_02516 468059.AUHA01000009_gene2809 3.6e-22 111.3 Bacteroidetes Bacteria 2B5U2@1,31YPU@2,4P49N@976 NA|NA|NA S Family of unknown function (DUF695) MAG.T2.48_02517 1121382.JQKG01000029_gene2690 3.2e-55 221.9 Bacteria 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria COG1091@1,COG1091@2 NA|NA|NA M dTDP-4-dehydrorhamnose reductase activity MAG.T2.48_02521 69042.WH5701_04205 2.4e-61 241.5 Synechococcus 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1G3YH@1117,1GZJQ@1129,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification MAG.T2.48_02522 1144275.COCOR_06346 1e-09 71.6 Proteobacteria ko:K07052,ko:K09696 ko02010,ko02020,map02010,map02020 M00253 ko00000,ko00001,ko00002,ko02000 3.A.1.115 Bacteria 1RI59@1224,COG1266@1,COG1266@2 NA|NA|NA S PFAM Abortive infection protein MAG.T2.48_02524 1122137.AQXF01000005_gene1270 2.6e-11 75.1 Alphaproteobacteria Bacteria 1NB0A@1224,2E42N@1,2UHGU@28211,32YZ4@2 NA|NA|NA MAG.T2.48_02526 1279019.ARQK01000049_gene16 2.4e-19 103.2 Chromatiales corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1MX09@1224,1T05M@1236,1WXY2@135613,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions MAG.T2.48_02527 1142394.PSMK_31800 4.6e-13 82.0 Bacteria Bacteria COG0398@1,COG0398@2 NA|NA|NA M Pfam SNARE associated Golgi protein MAG.T2.48_02528 1049564.TevJSym_ab01230 1.7e-70 273.1 unclassified Gammaproteobacteria 2.1.1.242,2.1.1.303,2.1.1.319 ko:K11434,ko:K15984,ko:K20421 ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922 M00830 R10963,R11216,R11217,R11219 RC00003,RC00392,RC02120,RC03388,RC03390 ko00000,ko00001,ko00002,ko01000,ko03009,ko03036 Bacteria 1J8AJ@118884,1R79F@1224,1RY3Z@1236,COG2242@1,COG2242@2 NA|NA|NA H protein methyltransferase activity MAG.T2.48_02530 575540.Isop_0271 1.4e-59 236.9 Planctomycetes ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 iYL1228.KPN_03597,ic_1306.c3945 Bacteria 2IXUE@203682,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T2.48_02531 1346330.M472_01855 7.6e-23 115.2 Sphingobacteriia dsbE ko:K02199,ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1IXI5@117747,4NQ70@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like domain MAG.T2.48_02532 530564.Psta_2024 1.7e-46 193.4 Planctomycetes panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYUG@203682,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate MAG.T2.48_02533 1267534.KB906754_gene3751 4.7e-142 511.1 Acidobacteriia iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 iPC815.YPO2896,iYL1228.KPN_02862 Bacteria 2JI55@204432,3Y3CG@57723,COG1104@1,COG1104@2 NA|NA|NA E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins MAG.T2.48_02534 278963.ATWD01000001_gene2224 9.4e-50 203.0 Acidobacteriia iscU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055 Bacteria 2JJ45@204432,3Y4B9@57723,COG0822@1,COG0822@2 NA|NA|NA C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters MAG.T2.48_02535 1142394.PSMK_03230 5.3e-38 164.1 Planctomycetes nfuA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K07400,ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2J01F@203682,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T2.48_02536 313612.L8106_14825 2.7e-115 422.2 Oscillatoriales desD 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 R07063 RC00917 ko00000,ko00001,ko01000,ko01004 iJN678.desD_des6_ Bacteria 1G2GY@1117,1H9RP@1150,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T2.48_02537 886293.Sinac_7219 9.9e-60 236.9 Planctomycetes Bacteria 2IZ9J@203682,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T2.48_02538 886293.Sinac_7220 4.7e-74 285.8 Planctomycetes Bacteria 2IZC4@203682,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T2.48_02539 411463.EUBVEN_00667 2.8e-13 82.4 Eubacteriaceae yocH ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VGG7@1239,25NR6@186801,25XCK@186806,COG3584@1,COG3584@2 NA|NA|NA N 3D domain MAG.T2.48_02540 1122179.KB890415_gene1999 8.2e-18 99.8 Sphingobacteriia 3.4.24.3 ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria 1IXQ8@117747,4NYN2@976,COG3291@1,COG3291@2,COG4412@1,COG4412@2 NA|NA|NA G Reprolysin (M12B) family zinc metalloprotease MAG.T2.48_02542 1142394.PSMK_26830 1.3e-134 486.9 Planctomycetes comM ko:K06400,ko:K07391 ko00000 Bacteria 2IWTT@203682,COG0606@1,COG0606@2 NA|NA|NA O PFAM Magnesium chelatase, ChlI subunit MAG.T2.48_02543 1123508.JH636442_gene4155 2.4e-235 822.4 Planctomycetes putA 1.2.1.88,1.5.5.2 ko:K00294,ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 iAF987.Gmet_3512 Bacteria 2IX0I@203682,COG0506@1,COG0506@2,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T2.48_02544 1121459.AQXE01000005_gene1549 6.2e-96 358.2 Desulfovibrionales GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11,2.4.1.18 ko:K16149,ko:K16150 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R00292,R02110 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GH57,GT4 Bacteria 1R6U0@1224,2M8ZZ@213115,2WJXW@28221,42Q1W@68525,COG0297@1,COG0297@2 NA|NA|NA G Starch synthase catalytic domain MAG.T2.48_02546 1142394.PSMK_05400 5e-51 208.4 Planctomycetes prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2IYX6@203682,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif MAG.T2.48_02547 1142394.PSMK_22020 1.3e-77 297.4 Planctomycetes Bacteria 2IYBJ@203682,COG0784@1,COG0784@2,COG2203@1,COG2203@2 NA|NA|NA T response regulator receiver MAG.T2.48_02548 1121481.AUAS01000003_gene3694 1.7e-51 209.5 Cytophagia gldA 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 Bacteria 47KF6@768503,4NEH0@976,COG1131@1,COG1131@2 NA|NA|NA V TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA MAG.T2.48_02549 1256908.HMPREF0373_02673 1.5e-10 75.5 Eubacteriaceae gldG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TT1J@1239,24BC2@186801,25VKY@186806,COG1277@1,COG1277@2,COG3225@1,COG3225@2 NA|NA|NA N ABC-type uncharacterized transport system MAG.T2.48_02550 478741.JAFS01000001_gene1166 1.7e-10 74.3 unclassified Verrucomicrobia Bacteria 2DN50@1,32VJ4@2,37FXR@326457,46V62@74201 NA|NA|NA S Domain of unknown function (DUF4340) MAG.T2.48_02551 589865.DaAHT2_1279 4.2e-65 255.4 Desulfobacterales ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iLJ478.TM1828 Bacteria 1MUWT@1224,2MIE9@213118,2WIP2@28221,42NBS@68525,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate MAG.T2.48_02552 1340493.JNIF01000003_gene4082 3.8e-19 103.2 Bacteria 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria COG2204@1,COG2204@2,COG2208@1,COG2208@2 NA|NA|NA T phosphoserine phosphatase activity MAG.T2.48_02553 1142394.PSMK_22290 1.2e-249 869.4 Planctomycetes ko:K02355 ko00000,ko03012,ko03029 Bacteria 2IXUD@203682,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome MAG.T2.48_02554 1142394.PSMK_19530 2.7e-42 179.5 Planctomycetes 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2J4X4@203682,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T2.48_02555 1123242.JH636434_gene4709 1.3e-24 119.4 Planctomycetes rbpA Bacteria 2IZPY@203682,COG0724@1,COG0724@2 NA|NA|NA S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAG.T2.48_02556 1142394.PSMK_00940 5.4e-116 424.5 Planctomycetes mnmA 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 2IXFF@203682,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 MAG.T2.48_02557 525373.HMPREF0766_13827 2.5e-152 545.0 Sphingobacteriia fbaB GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640 Bacteria 1IPKA@117747,4NEUM@976,COG1830@1,COG1830@2 NA|NA|NA G Aldolase MAG.T2.48_02559 290315.Clim_0660 1.8e-36 158.7 Bacteria ko:K09922 ko00000 Bacteria COG3169@1,COG3169@2 NA|NA|NA S Protein conserved in bacteria MAG.T2.48_02560 1487953.JMKF01000006_gene5843 3.2e-35 155.6 Oscillatoriales Bacteria 1GQX4@1117,1HI3P@1150,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain MAG.T2.48_02561 313628.LNTAR_12671 1.1e-114 421.0 Bacteria cadA 3.6.3.3,3.6.3.5,3.6.3.54 ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 Bacteria COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase MAG.T2.48_02562 1304885.AUEY01000096_gene2839 8.2e-188 664.1 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity MAG.T2.48_02563 1142394.PSMK_23340 1.6e-55 223.4 Planctomycetes 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 2J3F6@203682,COG2208@1,COG2208@2 NA|NA|NA KT Sigma factor PP2C-like phosphatases MAG.T2.48_02564 1142394.PSMK_22320 7.3e-85 320.9 Planctomycetes gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2IWWN@203682,COG0240@1,COG0240@2 NA|NA|NA I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase MAG.T2.48_02565 1121472.AQWN01000008_gene1877 1.1e-14 85.9 Peptococcaceae ptsH ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,24QIP@186801,2634E@186807,COG1925@1,COG1925@2 NA|NA|NA G TIGRFAM Phosphotransferase System MAG.T2.48_02566 314230.DSM3645_09087 4.6e-29 134.4 Planctomycetes ptsN 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IZ73@203682,COG1762@1,COG1762@2 NA|NA|NA G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 MAG.T2.48_02567 545276.KB898725_gene790 4.9e-16 90.5 Chromatiales raiA ko:K05808 ko00000,ko03009 Bacteria 1MZHW@1224,1S8U1@1236,1WYWY@135613,COG1544@1,COG1544@2 NA|NA|NA J Sigma 54 modulation protein MAG.T2.48_02569 575540.Isop_0337 2.1e-35 156.0 Planctomycetes purN 2.1.2.2,6.3.2.6,6.3.4.13 ko:K11175,ko:K13713 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04144,R04325,R04326,R04591 RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS04225 Bacteria 2IZ96@203682,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate MAG.T2.48_02570 1167006.UWK_02191 6.7e-18 97.1 Bacteria yciA ko:K10806 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria COG1607@1,COG1607@2 NA|NA|NA I acyl-coa hydrolase MAG.T2.48_02571 1173023.KE650771_gene5252 2.3e-24 119.8 Cyanobacteria Bacteria 1G8MF@1117,COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T2.48_02572 1142394.PSMK_29200 0.0 1210.3 Planctomycetes ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2IXFK@203682,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T2.48_02574 1142394.PSMK_19170 3.3e-244 851.3 Planctomycetes uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2IWS1@203682,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage MAG.T2.48_02577 1449336.JQLO01000001_gene738 2.5e-16 91.7 Carnobacteriaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,27FPN@186828,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage MAG.T2.48_02580 357808.RoseRS_0010 1.1e-68 267.7 Chloroflexia Bacteria 2G8T5@200795,376FH@32061,COG0823@1,COG0823@2 NA|NA|NA U WD40-like Beta Propeller Repeat MAG.T2.48_02581 243090.RB11027 7.7e-38 166.0 Planctomycetes lolE-2 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IYEX@203682,COG0577@1,COG0577@2,COG4591@1,COG4591@2 NA|NA|NA V ABC transport system integral membrane protein MAG.T2.48_02582 314230.DSM3645_28492 2.1e-52 212.6 Planctomycetes ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IYZ3@203682,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner MAG.T2.48_02583 1396141.BATP01000007_gene5666 3.8e-29 134.4 Verrucomicrobiae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IUJ1@203494,46VKU@74201,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein MAG.T2.48_02585 1142394.PSMK_08540 2.2e-48 199.1 Planctomycetes cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25 ko:K00800,ko:K00945,ko:K03977 ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230 M00022,M00052 R00158,R00512,R01665,R03460 RC00002,RC00350 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IZ6S@203682,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily MAG.T2.48_02586 1142394.PSMK_07740 2.5e-37 162.5 Planctomycetes cmk 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IZVC@203682,COG0204@1,COG0204@2 NA|NA|NA I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase MAG.T2.48_02587 1142394.PSMK_29560 4.8e-73 282.0 Planctomycetes cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2IXYM@203682,COG0617@1,COG0617@2 NA|NA|NA H tRNA nucleotidyltransferase poly(A) polymerase MAG.T2.48_02589 1078085.HMPREF1210_00371 3.8e-10 73.2 Planococcaceae yqeZ ko:K07403 ko00000 Bacteria 1TR54@1239,26CYG@186818,4H9P9@91061,COG1030@1,COG1030@2 NA|NA|NA O NfeD-like C-terminal, partner-binding MAG.T2.48_02590 1142394.PSMK_15560 5e-42 178.7 Planctomycetes pilI Bacteria 2IYX5@203682,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component MAG.T2.48_02591 1142394.PSMK_15610 1.7e-49 204.5 Bacteria Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion MAG.T2.48_02592 1218075.BAYA01000025_gene5365 9.7e-21 107.8 Burkholderiaceae hflC2 ko:K04087 M00742 ko00000,ko00002,ko01000 Bacteria 1K5EI@119060,1P392@1224,2W9W1@28216,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues MAG.T2.48_02593 1142394.PSMK_15630 5e-22 112.8 Bacteria ko:K04088,ko:K14393 M00742 ko00000,ko00002,ko01000,ko02000 2.A.21.7 Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion MAG.T2.48_02594 313628.LNTAR_12676 1.4e-85 323.6 Bacteria pilH ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1131@1,COG1131@2 NA|NA|NA V ATPase activity MAG.T2.48_02595 1142394.PSMK_15650 9.3e-42 178.7 Bacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1277@1,COG1277@2 NA|NA|NA MAG.T2.48_02596 1142394.PSMK_15660 7.3e-60 238.8 Planctomycetes 2.7.7.7 ko:K02343,ko:K03749 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IXFB@203682,COG3147@1,COG3147@2 NA|NA|NA S Non-essential cell division protein that could be required for efficient cell constriction MAG.T2.48_02597 1496688.ER33_11770 1.3e-58 233.0 Cyanobium 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 Bacteria 1G06Y@1117,22TKF@167375,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family MAG.T2.48_02599 1142394.PSMK_27100 4.5e-13 80.9 Bacteria rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria COG0594@1,COG0594@2 NA|NA|NA J ribonuclease P activity MAG.T2.48_02600 1142394.PSMK_10130 1.8e-102 380.2 Planctomycetes clcA ko:K03281 ko00000 2.A.49 Bacteria 2IY1G@203682,COG0038@1,COG0038@2,COG0517@1,COG0517@2 NA|NA|NA P COG0038 Chloride channel protein EriC MAG.T2.48_02601 521674.Plim_2053 6.7e-08 63.2 Planctomycetes rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2J0KS@203682,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits MAG.T2.48_02603 1385517.N800_00780 8.5e-181 640.6 Xanthomonadales fusA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1MVVY@1224,1RYCE@1236,1X4EX@135614,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G MAG.T2.48_02606 96561.Dole_2531 3.9e-10 71.6 Bacteria ko:K08978 ko00000,ko02000 2.A.7.2 Bacteria COG2510@1,COG2510@2 NA|NA|NA EG membrane MAG.T2.48_02607 216432.CA2559_02120 7.2e-12 78.2 Flavobacteriia ygiM ko:K07184 ko00000 Bacteria 1HYKU@117743,4NF5V@976,COG0457@1,COG0457@2,COG3807@1,COG3807@2 NA|NA|NA T tetratricopeptide repeat MAG.T2.48_02608 344747.PM8797T_13992 1.4e-39 171.4 Planctomycetes Bacteria 2IWZ3@203682,COG0457@1,COG0457@2 NA|NA|NA S Oxygen tolerance MAG.T2.48_02609 497964.CfE428DRAFT_3460 4.1e-09 69.7 Verrucomicrobia batB ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 46SP8@74201,COG0457@1,COG0457@2,COG2304@1,COG2304@2 NA|NA|NA J von Willebrand factor (vWF) type A domain MAG.T2.48_02610 344747.PM8797T_13987 1.5e-61 243.4 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IYZ1@203682,COG0457@1,COG0457@2,COG2304@1,COG2304@2 NA|NA|NA A von Willebrand factor, type A MAG.T2.48_02611 344747.PM8797T_13982 2.3e-76 292.7 Planctomycetes batA ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IYWC@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.48_02612 502025.Hoch_0521 5e-23 115.5 Bacteria Bacteria 2DQN8@1,337RD@2 NA|NA|NA MAG.T2.48_02613 344747.PM8797T_13972 4.1e-87 328.2 Planctomycetes GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2IXT7@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.48_02614 237368.SCABRO_02223 3.2e-64 251.5 Planctomycetes moxR ko:K03924 ko00000,ko01000 Bacteria 2IX23@203682,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T2.48_02615 886293.Sinac_0339 1.7e-09 70.1 Planctomycetes Bacteria 2IWU6@203682,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T2.48_02617 861299.J421_2862 4.6e-203 714.1 Gemmatimonadetes ahcY GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 1ZTEF@142182,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine MAG.T2.48_02618 278957.ABEA03000157_gene621 4.5e-43 182.6 Opitutae Bacteria 2F18R@1,33U9V@2,3K9D4@414999,46V4A@74201 NA|NA|NA MAG.T2.48_02619 278957.ABEA03000157_gene614 4.5e-80 305.1 Opitutae phnT 3.6.3.30 ko:K02010 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 Bacteria 3K8TY@414999,46UMI@74201,COG3842@1,COG3842@2 NA|NA|NA E ATPases associated with a variety of cellular activities MAG.T2.48_02620 794903.OPIT5_20100 4.1e-62 245.4 Opitutae ftpB ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 3K8V1@414999,46V2H@74201,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein MAG.T2.48_02621 794903.OPIT5_20090 2.4e-133 482.6 Opitutae ftpA ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 3K8P9@414999,46U4B@74201,COG1178@1,COG1178@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component MAG.T2.48_02622 1033732.CAHI01000030_gene827 4.8e-07 62.0 Rikenellaceae Bacteria 22UZB@171550,2CG1Y@1,2FPRX@200643,2Z9QX@2,4NJI6@976 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T2.48_02623 1231185.BAMP01000090_gene2462 1.5e-45 188.7 Phyllobacteriaceae Bacteria 1RHWU@1224,2UA4V@28211,43RCI@69277,COG0662@1,COG0662@2 NA|NA|NA G Cupin MAG.T2.48_02624 497965.Cyan7822_5347 1.4e-65 256.1 Cyanothece marC ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1G6S9@1117,3KIGD@43988,COG2095@1,COG2095@2 NA|NA|NA U PFAM multiple antibiotic resistance (MarC)-related protein MAG.T2.48_02625 1125973.JNLC01000010_gene1554 2.7e-07 60.8 Bradyrhizobiaceae Bacteria 1RECR@1224,2U6MH@28211,3JYJP@41294,COG2020@1,COG2020@2 NA|NA|NA O Isoprenylcysteine carboxyl methyltransferase MAG.T2.48_02626 379066.GAU_0037 2.8e-35 154.8 Bacteria Bacteria COG4430@1,COG4430@2 NA|NA|NA F Bacteriocin-protection, YdeI or OmpD-Associated MAG.T2.48_02628 1454004.AW11_02123 2.6e-42 178.3 Proteobacteria 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1RK5M@1224,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T2.48_02629 530564.Psta_1178 7.6e-222 776.5 Planctomycetes rafA 3.1.3.1,3.1.3.5,3.2.1.22,3.6.1.45 ko:K01077,ko:K07407,ko:K11751 ko00052,ko00230,ko00240,ko00561,ko00600,ko00603,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00052,map00230,map00240,map00561,map00600,map00603,map00730,map00760,map00790,map01100,map01110,map02020 M00126 R00183,R00511,R00963,R01101,R01103,R01104,R01126,R01194,R01227,R01329,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R02926,R03346,R03634,R04019,R04470,R04620,R05549,R05961,R06091 RC00017,RC00049,RC00059,RC00451 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2IZER@203682,COG1657@1,COG1657@2,COG3345@1,COG3345@2 NA|NA|NA G Carbohydrate esterase, sialic acid-specific acetylesterase MAG.T2.48_02630 1123508.JH636446_gene6214 6.5e-109 401.0 Planctomycetes 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IY0I@203682,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T2.48_02631 1142394.PSMK_06290 2.2e-89 335.9 Planctomycetes fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 iUTI89_1310.UTI89_C4836,ic_1306.c5329 Bacteria 2IWT3@203682,COG0158@1,COG0158@2 NA|NA|NA G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 MAG.T2.48_02632 1454004.AW11_01224 1.8e-17 95.9 Betaproteobacteria Bacteria 1QW8Y@1224,2DMII@1,2WHFR@28216,32RTH@2 NA|NA|NA S CHRD domain MAG.T2.48_02633 1382306.JNIM01000001_gene1561 2.5e-148 533.5 Chloroflexi tri ko:K08676 ko00000,ko01000,ko01002 Bacteria 2G64C@200795,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog MAG.T2.48_02634 575540.Isop_2474 6.9e-07 61.2 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2J123@203682,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.48_02635 551275.KB899544_gene1610 7.7e-27 129.0 Alphaproteobacteria Bacteria 1MV1P@1224,2VF7J@28211,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.48_02638 661478.OP10G_1650 5.1e-194 684.1 Bacteria prpD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 R04424 RC01152 ko00000,ko00001,ko01000 Bacteria COG2079@1,COG2079@2 NA|NA|NA S 2-methylcitrate dehydratase activity MAG.T2.48_02639 1123242.JH636435_gene1310 1e-63 250.8 Planctomycetes argK 5.4.99.2 ko:K01849,ko:K07588 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 2J2GB@203682,COG1703@1,COG1703@2,COG2185@1,COG2185@2 NA|NA|NA E ArgK protein MAG.T2.48_02641 1041159.AZUW01000009_gene4548 2.1e-105 390.2 Proteobacteria Bacteria 1R7H7@1224,COG2304@1,COG2304@2 NA|NA|NA O von Willebrand factor type A domain MAG.T2.48_02644 1142394.PSMK_02940 0.0 1417.5 Planctomycetes nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IX3H@203682,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen MAG.T2.48_02645 1142394.PSMK_02910 4.5e-79 300.8 Planctomycetes dcd GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZ2N@203682,COG0717@1,COG0717@2 NA|NA|NA F dUTPase MAG.T2.48_02646 1142394.PSMK_16820 2.1e-147 530.0 Planctomycetes pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2IWTI@203682,COG0210@1,COG0210@2 NA|NA|NA L COG0210 Superfamily I DNA and RNA MAG.T2.48_02649 479434.Sthe_2440 2.2e-148 533.1 Chloroflexi 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 2GBNH@200795,COG1505@1,COG1505@2 NA|NA|NA E Peptidase S9, prolyl oligopeptidase active site domain protein MAG.T2.48_02650 1123072.AUDH01000009_gene432 5.7e-116 424.5 Rhodospirillales serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 iYL1228.KPN_03348 Bacteria 1MU5Z@1224,2JPYH@204441,2TR0F@28211,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family MAG.T2.48_02651 926550.CLDAP_03880 1.6e-45 189.9 Chloroflexi map 1.17.1.1,3.4.11.18 ko:K00523,ko:K01265 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000,ko01002 Bacteria 2G6AV@200795,COG0024@1,COG0024@2 NA|NA|NA J TIGRFAM methionine aminopeptidase, type I MAG.T2.48_02652 292459.STH3191 4.6e-73 282.0 Clostridia hutI 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2J@1239,24AGR@186801,COG1228@1,COG1228@2 NA|NA|NA Q Belongs to the metallo-dependent hydrolases superfamily. HutI family MAG.T2.48_02656 298386.PBPRA2792 2.5e-25 123.2 Vibrionales phuW Bacteria 1RAAM@1224,1T1A0@1236,1Y31C@135623,COG3016@1,COG3016@2 NA|NA|NA S Haem-binding uptake, Tiki superfamily, ChaN MAG.T2.48_02657 8496.XP_006265195.1 5e-60 239.6 Vertebrata CPA5 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.11.17,3.4.17.1,3.4.17.15,3.4.17.2,3.4.17.20 ko:K01291,ko:K01298,ko:K01300,ko:K04515,ko:K08779,ko:K08780,ko:K08781 ko04012,ko04020,ko04024,ko04066,ko04114,ko04217,ko04261,ko04310,ko04360,ko04610,ko04614,ko04713,ko04720,ko04722,ko04725,ko04728,ko04740,ko04745,ko04750,ko04911,ko04912,ko04916,ko04921,ko04922,ko04925,ko04934,ko04971,ko04972,ko04974,ko05031,ko05152,ko05200,ko05205,ko05214,map04012,map04020,map04024,map04066,map04114,map04217,map04261,map04310,map04360,map04610,map04614,map04713,map04720,map04722,map04725,map04728,map04740,map04745,map04750,map04911,map04912,map04916,map04921,map04922,map04925,map04934,map04971,map04972,map04974,map05031,map05152,map05200,map05205,map05214 ko00000,ko00001,ko01000,ko01001,ko01002,ko03110 Metazoa 38DUK@33154,3BA6U@33208,3CUQS@33213,481VD@7711,490AY@7742,COG2866@1,KOG2650@2759 NA|NA|NA O Carboxypeptidase MAG.T2.48_02658 886293.Sinac_6200 1.5e-47 196.1 Planctomycetes efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2IZ4X@203682,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase MAG.T2.48_02659 269799.Gmet_1031 4.4e-09 69.3 Desulfuromonadales Bacteria 1N01A@1224,2CG1Y@1,2WQED@28221,32WID@2,42UK0@68525,43SMQ@69541 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T2.48_02660 1142394.PSMK_20910 8.2e-76 290.4 Planctomycetes fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IYD3@203682,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH MAG.T2.48_02661 1142394.PSMK_11800 3.8e-34 152.5 Planctomycetes ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 2IZ5M@203682,COG0486@1,COG0486@2 NA|NA|NA S Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family MAG.T2.48_02662 1142394.PSMK_11780 2.9e-57 228.8 Planctomycetes coaX 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 Bacteria 2J0M0@203682,COG1521@1,COG1521@2 NA|NA|NA F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis MAG.T2.48_02663 1283300.ATXB01000002_gene2824 5.9e-51 208.0 Methylococcales dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 Bacteria 1MVAT@1224,1RPU0@1236,1XE1X@135618,COG0115@1,COG0115@2 NA|NA|NA EH PFAM Aminotransferase, class IV MAG.T2.48_02664 1168034.FH5T_08655 5.8e-61 241.1 Bacteroidetes sgcQ ko:K06971 ko00000 Bacteria 4P0R6@976,COG0434@1,COG0434@2 NA|NA|NA S BtpA family MAG.T2.48_02666 469383.Cwoe_5648 1.7e-11 76.3 Rubrobacteria 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2HQKA@201174,4CS5Q@84995,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase MAG.T2.48_02667 1142394.PSMK_29730 3.9e-39 168.7 Planctomycetes Bacteria 2IYV8@203682,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T2.48_02668 449447.MAE_34890 3.2e-128 464.9 Cyanobacteria gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12,1.2.1.59 ko:K00134,ko:K00150 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061,R01063 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 Bacteria 1G1CS@1117,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family MAG.T2.48_02669 306281.AJLK01000092_gene3050 3.3e-20 105.5 Cyanobacteria Bacteria 1G6XJ@1117,2BV24@1,32QEZ@2 NA|NA|NA S TIGRFAM PEP-CTERM protein sorting domain MAG.T2.48_02671 661478.OP10G_0724 6.4e-86 324.7 Bacteria ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis MAG.T2.48_02672 1123508.JH636450_gene7224 9.1e-122 443.7 Planctomycetes lhgO 1.1.99.2 ko:K00109,ko:K15736 ko00650,map00650 R03534 RC00031 ko00000,ko00001,ko01000 Bacteria 2IX3W@203682,COG0579@1,COG0579@2 NA|NA|NA S FAD dependent oxidoreductase MAG.T2.48_02673 313628.LNTAR_05151 1.3e-12 80.1 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.48_02674 1267533.KB906733_gene3472 2.5e-60 240.7 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.48_02675 530564.Psta_1242 7.8e-157 560.5 Planctomycetes 1.5.99.6 ko:K00316 ko00330,ko00410,ko01100,map00330,map00410,map01100 R01914,R01915 RC00053,RC00225 ko00000,ko00001,ko01000 Bacteria 2J2DT@203682,COG1231@1,COG1231@2 NA|NA|NA E Prenylcysteine lyase MAG.T2.48_02676 530564.Psta_1241 2.6e-54 219.2 Planctomycetes Bacteria 2A5VV@1,2J4JR@203682,30UMQ@2 NA|NA|NA MAG.T2.48_02677 530564.Psta_1240 8.3e-106 390.6 Bacteria Bacteria COG3503@1,COG3503@2 NA|NA|NA J Membrane MAG.T2.48_02678 530564.Psta_4391 2e-32 145.6 Planctomycetes Bacteria 2ECSD@1,2J168@203682,336PY@2 NA|NA|NA MAG.T2.48_02679 1415779.JOMH01000001_gene1098 9e-25 120.6 Gammaproteobacteria Bacteria 1NA3F@1224,1SF94@1236,2E64M@1,330TG@2 NA|NA|NA MAG.T2.48_02680 1112214.AHIS01000050_gene2409 5.5e-78 298.1 Sphingomonadales 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1R953@1224,2K8W0@204457,2V1TG@28211,COG0332@1,COG0332@2 NA|NA|NA I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MAG.T2.48_02681 452637.Oter_1515 5.8e-105 387.9 Verrucomicrobia acrA ko:K02005 ko00000 Bacteria 46UZZ@74201,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like MAG.T2.48_02682 1403819.BATR01000150_gene5076 9.8e-97 359.8 Verrucomicrobiae tptC ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVI3@203494,46UWZ@74201,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T2.48_02683 452637.Oter_1513 8.3e-133 480.3 Bacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity MAG.T2.48_02684 452637.Oter_1512 1.2e-147 529.6 Opitutae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 3K9RN@414999,46YY4@74201,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T2.48_02685 1123242.JH636434_gene4709 7.3e-22 109.8 Planctomycetes rbpA Bacteria 2IZPY@203682,COG0724@1,COG0724@2 NA|NA|NA S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAG.T2.48_02687 296591.Bpro_0678 0.0 1205.7 Comamonadaceae katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 1MUBF@1224,2VH5H@28216,4A9PE@80864,COG0376@1,COG0376@2 NA|NA|NA P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity MAG.T2.48_02688 926550.CLDAP_32510 1.8e-43 182.6 Chloroflexi furA ko:K03711,ko:K22297 ko00000,ko03000 Bacteria 2G9HJ@200795,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family MAG.T2.48_02689 118166.JH976537_gene4234 4.6e-112 412.1 Oscillatoriales 3.1.4.46 ko:K01126,ko:K07093 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1GQ3P@1117,1HI0H@1150,COG3211@1,COG3211@2,COG4222@1,COG4222@2 NA|NA|NA Q Glycerophosphoryl diester phosphodiesterase family MAG.T2.48_02690 864051.BurJ1DRAFT_0942 3.2e-36 159.1 Proteobacteria Bacteria 1P0W9@1224,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T2.48_02692 994573.T472_0209550 2e-20 105.5 Clostridiaceae ko:K09707 ko00000 Bacteria 1V9Y8@1239,24JKN@186801,36K09@31979,COG3603@1,COG3603@2 NA|NA|NA S ACT domain MAG.T2.48_02693 640081.Dsui_1569 1.5e-171 609.4 Rhodocyclales pap Bacteria 1MVE2@1224,2KU63@206389,2VGZV@28216,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T2.48_02694 1170562.Cal6303_2073 9.9e-15 88.2 Bacteria Bacteria COG5563@1,COG5563@2 NA|NA|NA MAG.T2.48_02695 382464.ABSI01000010_gene3721 3.8e-70 271.6 Verrucomicrobiae Bacteria 2ITSE@203494,46SNA@74201,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T2.48_02696 740709.A10D4_04670 1.4e-25 123.6 Idiomarinaceae Bacteria 1MUBQ@1224,1RQJT@1236,2QFPB@267893,COG1028@1,COG1028@2 NA|NA|NA IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis MAG.T2.48_02697 382464.ABSI01000010_gene3727 1.3e-93 350.1 Bacteria phaC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 ko:K03821 ko00650,map00650 R04254 RC00004 ko00000,ko00001,ko01000 iJN678.phbC Bacteria COG3243@1,COG3243@2 NA|NA|NA I poly(R)-hydroxyalkanoic acid synthase MAG.T2.48_02700 177437.HRM2_42080 6.7e-10 71.2 Desulfobacterales phaR Bacteria 1RHRC@1224,2MKS1@213118,2WQ0S@28221,42WB9@68525,COG5394@1,COG5394@2 NA|NA|NA S PHB/PHA accumulation regulator DNA-binding domain MAG.T2.48_02701 743720.Psefu_2713 6e-41 174.9 Gammaproteobacteria Bacteria 1QV4H@1224,1T280@1236,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T2.48_02702 671143.DAMO_1499 1.5e-117 429.9 unclassified Bacteria mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 2NP6V@2323,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter MAG.T2.48_02703 1156937.MFUM_1010016 5.9e-27 127.1 unclassified Verrucomicrobia mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 37HBV@326457,46WPW@74201,COG1970@1,COG1970@2 NA|NA|NA M Large-conductance mechanosensitive channel, MscL MAG.T2.48_02704 1183438.GKIL_3357 9.9e-82 310.8 Cyanobacteria entS ko:K08225 ko00000,ko02000 2.A.1.38 Bacteria 1G1NG@1117,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily MFS_1 MAG.T2.48_02705 1192868.CAIU01000015_gene1928 4.8e-84 318.2 Phyllobacteriaceae 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 1MVE0@1224,2TQPY@28211,43H9K@69277,COG1902@1,COG1902@2 NA|NA|NA C NADH flavin oxidoreductase NADH oxidase MAG.T2.48_02706 1121899.Q764_09130 1.9e-25 121.3 Flavobacterium Bacteria 1I3HF@117743,2NX4C@237,4NSVZ@976,COG2314@1,COG2314@2 NA|NA|NA S Pfam TM2 domain MAG.T2.48_02708 1234364.AMSF01000037_gene215 5.9e-11 73.6 Xanthomonadales Bacteria 1QB3Z@1224,1T6MV@1236,1XABE@135614,29A04@1,31DSZ@2 NA|NA|NA MAG.T2.48_02709 1121481.AUAS01000003_gene3874 3.7e-08 64.7 Cytophagia Bacteria 2DM9Y@1,32AJ6@2,47PRQ@768503,4NQQC@976 NA|NA|NA MAG.T2.48_02715 270374.MELB17_10873 1.7e-12 78.6 Gammaproteobacteria Bacteria 1N74C@1224,1SCNC@1236,COG3657@1,COG3657@2 NA|NA|NA S addiction module killer protein MAG.T2.48_02716 864051.BurJ1DRAFT_1922 2e-29 135.2 unclassified Burkholderiales Bacteria 1KMGR@119065,1N75D@1224,2VUBY@28216,COG3636@1,COG3636@2 NA|NA|NA K addiction module antidote protein MAG.T2.48_02718 1142394.PSMK_24550 1.9e-157 562.8 Planctomycetes ptsI 2.7.1.202,2.7.3.9 ko:K02768,ko:K08483,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 Bacteria 2IX08@203682,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) MAG.T2.48_02719 1142394.PSMK_24570 1.8e-135 490.7 Planctomycetes rne GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 3.1.26.12 ko:K08300 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2IWSS@203682,COG1530@1,COG1530@2 NA|NA|NA J TIGRFAM ribonuclease, Rne Rng family MAG.T2.48_02720 1142394.PSMK_24580 3e-93 349.0 Planctomycetes dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2IY3M@203682,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) MAG.T2.48_02721 1142394.PSMK_24590 1.5e-95 357.5 Planctomycetes rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 2IXWE@203682,COG0265@1,COG0265@2,COG0750@1,COG0750@2 NA|NA|NA M PDZ domain (Also known as DHR MAG.T2.48_02722 1142394.PSMK_26050 1.3e-30 140.2 Bacteria fabG7 1.1.1.100,1.1.1.401 ko:K00059,ko:K07535,ko:K21883 ko00051,ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00051,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220 M00083,M00540,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11339,R11671 RC00029,RC00089,RC00117,RC00154 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria COG4221@1,COG4221@2 NA|NA|NA IQ oxidoreductase activity MAG.T2.48_02723 1463856.JOHY01000001_gene541 4.5e-11 75.5 Actinobacteria yoaK Bacteria 2GKDV@201174,COG3619@1,COG3619@2 NA|NA|NA S membrane MAG.T2.48_02724 1121423.JONT01000017_gene94 1.6e-29 136.0 Peptococcaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,24HD6@186801,261PA@186807,COG0691@1,COG0691@2 NA|NA|NA J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene MAG.T2.48_02725 391625.PPSIR1_05583 5.4e-29 136.7 Myxococcales 3.1.3.64 ko:K07004,ko:K21302 ko00562,ko01100,ko05152,map00562,map01100,map05152 ko00000,ko00001,ko01000 Bacteria 1Q6DC@1224,2WYJ7@28221,2Z34H@29,432XR@68525,COG3227@1,COG3227@2 NA|NA|NA E Zinc metalloprotease (Elastase) MAG.T2.48_02727 292459.STH1783 4e-52 212.2 Clostridia rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,248UG@186801,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T2.48_02729 595460.RRSWK_07188 8.5e-13 82.4 Bacteria 3.4.24.3 ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity MAG.T2.48_02730 757424.Hsero_3305 2.9e-24 119.4 Oxalobacteraceae rbn GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07058 ko00000 Bacteria 1QICW@1224,2VJNM@28216,472DM@75682,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB MAG.T2.48_02734 1142394.PSMK_19510 5.3e-80 303.9 Planctomycetes nuoB 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IZ30@203682,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_02735 1123060.JONP01000014_gene4171 6.8e-67 260.8 Rhodospirillales cobB GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 ko:K12410 ko00000,ko01000 Bacteria 1MUK1@1224,2JR75@204441,2TV1Q@28211,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form MAG.T2.48_02736 981383.AEWH01000059_gene2180 1.7e-08 65.9 Bacilli Bacteria 1UYI5@1239,4HF86@91061,COG4312@1,COG4312@2 NA|NA|NA S Bacterial protein of unknown function (DUF899) MAG.T2.48_02737 1336208.JADY01000002_gene352 1.2e-81 310.5 Rhodospirillales aatA 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1MW0Z@1224,2JQGR@204441,2TRPK@28211,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase MAG.T2.48_02738 794903.OPIT5_20120 4.8e-36 158.3 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.48_02739 1142394.PSMK_28940 1.7e-100 372.9 Planctomycetes prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2IWU3@203682,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA MAG.T2.48_02740 1122614.JHZF01000001_gene365 1.2e-48 200.7 Oceanicola ko:K11080 ko02010,map02010 M00301 ko00000,ko00001,ko00002,ko02000 3.A.1.11.3 Bacteria 1MU3I@1224,2PDGR@252301,2TQMJ@28211,COG3842@1,COG3842@2 NA|NA|NA E import. Responsible for energy coupling to the transport system MAG.T2.48_02741 448385.sce2296 1.1e-151 543.9 Myxococcales 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 Bacteria 1MW01@1224,2WJF7@28221,2YX9T@29,42NSN@68525,COG3408@1,COG3408@2 NA|NA|NA G High confidence in function and specificity MAG.T2.48_02743 861299.J421_5672 0.0 1129.4 Bacteria 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria COG2334@1,COG2334@2 NA|NA|NA S homoserine kinase activity MAG.T2.48_02744 530564.Psta_4267 1.6e-13 84.0 Planctomycetes sagS 2.7.13.3 ko:K03320,ko:K20973 ko02020,ko02025,map02020,map02025 M00820 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 1.A.11 Bacteria 2IX1S@203682,COG0004@1,COG0004@2,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T2.48_02745 1210884.HG799463_gene9989 2.7e-37 162.2 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZXS@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.48_02746 497964.CfE428DRAFT_3010 1.6e-246 859.8 Verrucomicrobia ko:K08676 ko00000,ko01000,ko01002 Bacteria 46TRH@74201,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease PDZ domain MAG.T2.48_02752 1123377.AUIV01000014_gene490 9.6e-19 102.4 Xanthomonadales 2.7.11.1 ko:K14949 ko05152,map05152 ko00000,ko00001,ko01000,ko01001 Bacteria 1MVEU@1224,1S0IU@1236,1X4DU@135614,COG0515@1,COG0515@2,COG5010@1,COG5010@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.48_02753 1142394.PSMK_00820 2.4e-38 165.6 Planctomycetes Bacteria 2J12F@203682,COG0500@1,COG2226@2 NA|NA|NA Q PFAM methyltransferase MAG.T2.48_02754 926564.KI911678_gene5264 3.2e-10 74.3 Promicromonosporaceae bpr GO:0005575,GO:0005576 3.2.1.4 ko:K01179,ko:K13276 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01002,ko03110 GH5,GH9 Bacteria 2HQIW@201174,4F5H7@85017,COG1404@1,COG1404@2,COG3055@1,COG3055@2 NA|NA|NA O Subtilase family MAG.T2.48_02755 1123389.ATXJ01000003_gene320 4.5e-52 211.8 Deinococcus-Thermus fprA1 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1WJ5P@1297,COG0491@1,COG0491@2 NA|NA|NA S COGs COG0491 Zn-dependent hydrolase including glyoxylase MAG.T2.48_02756 1121440.AUMA01000010_gene310 2.8e-10 72.8 Desulfovibrionales Bacteria 1QTTN@1224,2MBAK@213115,2X6XU@28221,43BJZ@68525,COG0596@1,COG0596@2 NA|NA|NA S Serine aminopeptidase, S33 MAG.T2.48_02757 1307759.JOMJ01000003_gene1736 4.2e-18 99.0 Desulfovibrionales Bacteria 1N0N6@1224,2MAB9@213115,2WS8I@28221,42V8E@68525,COG2982@1,COG2982@2 NA|NA|NA M Protein involved in outer membrane biogenesis MAG.T2.48_02758 448385.sce2225 1.1e-51 210.7 Myxococcales galK 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MVQD@1224,2WSYZ@28221,2YV2T@29,42Y39@68525,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family. GalK subfamily MAG.T2.48_02760 1121015.N789_11970 1.7e-89 337.0 Xanthomonadales pcpB Bacteria 1MUN4@1224,1RRWV@1236,1X75V@135614,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T2.48_02761 1301098.PKB_4827 1e-17 99.0 Gammaproteobacteria ko:K15547 ko00000,ko02000 2.A.85.6.1 Bacteria 1R0HK@1224,1RQSH@1236,COG1289@1,COG1289@2 NA|NA|NA S Resistance protein MAG.T2.48_02762 1304885.AUEY01000002_gene294 3.6e-95 355.9 Desulfobacterales ko:K07814 ko00000,ko02022 Bacteria 1RGKE@1224,2MI92@213118,2WIV3@28221,42QI9@68525,COG2203@1,COG2203@2,COG3437@1,COG3437@2 NA|NA|NA T GAF domain MAG.T2.48_02764 195105.CN97_09215 1.6e-34 153.3 Alphaproteobacteria ko:K06996 ko00000 Bacteria 1R81W@1224,2U6BE@28211,COG3324@1,COG3324@2 NA|NA|NA S glyoxalase bleomycin resistance protein dioxygenase MAG.T2.48_02765 378806.STAUR_1279 8.2e-79 300.8 Myxococcales ybbD 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVAJ@1224,2WN0Z@28221,2YUJN@29,42N8K@68525,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain MAG.T2.48_02766 335543.Sfum_3682 2.5e-17 95.9 Syntrophobacterales Bacteria 1RHV6@1224,2MQM3@213462,2WQ75@28221,42TN0@68525,COG2930@1,COG2930@2 NA|NA|NA S Las17-binding protein actin regulator MAG.T2.48_02767 448385.sce3935 1.4e-61 243.8 Myxococcales mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUD4@1224,2WJ60@28221,2YURG@29,42PDR@68525,COG1194@1,COG1194@2 NA|NA|NA L A G-specific MAG.T2.48_02769 344747.PM8797T_11299 4.5e-30 138.3 Planctomycetes psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXE7@203682,COG0688@1,COG0688@2 NA|NA|NA I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) MAG.T2.48_02770 240016.ABIZ01000001_gene2614 2.4e-10 73.6 Bacteria 3.1.4.3 ko:K01114,ko:K12287,ko:K15125,ko:K16191,ko:K20276 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,ko05133,map00562,map00564,map00565,map01100,map01110,map02024,map04919,map05133 R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko00536,ko01000,ko02000,ko02042,ko02044 1.B.6.1.3 Bacteria COG2373@1,COG2373@2,COG2885@1,COG2885@2,COG3210@1,COG3210@2,COG5563@1,COG5563@2 NA|NA|NA U Large extracellular alpha-helical protein MAG.T2.48_02773 398580.Dshi_2382 2.1e-09 69.3 Alphaproteobacteria ko:K15256 ko00000,ko01000,ko03016 Bacteria 1N2EQ@1224,2UC80@28211,COG0500@1,COG0500@2 NA|NA|NA Q methyltransferase MAG.T2.48_02774 1235792.C808_01936 1.2e-06 60.8 unclassified Lachnospiraceae Bacteria 1VAVV@1239,24N42@186801,27MMS@186928,COG2604@1,COG2604@2 NA|NA|NA S Protein of unknown function DUF115 MAG.T2.48_02775 376686.Fjoh_2054 1.9e-08 67.0 Bacteria Bacteria COG1372@1,COG1372@2 NA|NA|NA L intein-mediated protein splicing MAG.T2.48_02777 1388763.O165_013230 9e-36 158.3 Pseudomonas putida group czcC ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1NEZC@1224,1S1F9@1236,1YX6K@136845,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.48_02779 886293.Sinac_2095 8.7e-66 258.1 Planctomycetes ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 2IYDV@203682,COG0845@1,COG0845@2 NA|NA|NA M Barrel-sandwich domain of CusB or HlyD membrane-fusion MAG.T2.48_02780 448385.sce2737 0.0 1207.2 Myxococcales ko:K07787,ko:K15726 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 Bacteria 1NUIV@1224,2WTZ0@28221,2YUKM@29,42M0A@68525,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.48_02781 395494.Galf_2176 3.3e-207 728.4 Betaproteobacteria cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1MU08@1224,2VHKE@28216,COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase MAG.T2.48_02783 671143.DAMO_2664 5.7e-99 367.5 Bacteria Bacteria 2C205@1,30AGG@2 NA|NA|NA MAG.T2.48_02784 292414.TM1040_1587 4.5e-91 341.3 Ruegeria dam 2.1.1.72 ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Bacteria 1PQQV@1224,2V332@28211,4ND4P@97050,COG0338@1,COG0338@2 NA|NA|NA H D12 class N6 adenine-specific DNA methyltransferase MAG.T2.48_02785 525903.Taci_1503 3.9e-36 157.9 Bacteria Bacteria COG3547@1,COG3547@2 NA|NA|NA L Transposase (IS116 IS110 IS902 family) MAG.T2.48_02786 575540.Isop_2455 3e-134 485.3 Planctomycetes ko:K06400 ko00000 Bacteria 2IYJH@203682,COG1961@1,COG1961@2 NA|NA|NA L Site-specific recombinase, DNA invertase Pin MAG.T2.48_02787 575540.Isop_2456 7.3e-28 130.2 Planctomycetes Bacteria 2CJ67@1,2J0JF@203682,32WT5@2 NA|NA|NA MAG.T2.48_02789 1244869.H261_10467 1.2e-19 103.2 Rhodospirillales Bacteria 1RE56@1224,293DJ@1,2JX13@204441,2UDPW@28211,2ZQW1@2 NA|NA|NA MAG.T2.48_02790 1265502.KB905934_gene3176 4e-97 362.5 Comamonadaceae 3.5.2.10,6.3.4.20 ko:K01470,ko:K06920 ko00330,ko00790,ko01100,map00330,map00790,map01100 R01884,R09978 RC00615,RC00959 ko00000,ko00001,ko01000,ko03016 Bacteria 1MXFU@1224,2VJZT@28216,4AG1C@80864,COG0603@1,COG0603@2 NA|NA|NA F PP-loop superfamily ATPase MAG.T2.48_02792 679192.HMPREF9013_1318 1.3e-17 97.1 Erysipelotrichia Bacteria 1TR3B@1239,28HHC@1,2Z7T2@2,3VQ9J@526524 NA|NA|NA S AAA domain MAG.T2.48_02793 575540.Isop_2441 5.2e-44 184.1 Planctomycetes Bacteria 2CEI6@1,2J3S1@203682,2ZED5@2 NA|NA|NA S Protein of unknown function (DUF669) MAG.T2.48_02794 1218352.B597_019440 2.2e-11 74.3 Pseudomonas stutzeri group rusA GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.1.22.4 ko:K01160 ko00000,ko01000,ko03400 Bacteria 1N92D@1224,1TA3B@1236,1Z47G@136846,COG4570@1,COG4570@2 NA|NA|NA L Endodeoxyribonuclease RusA MAG.T2.48_02795 575540.Isop_2443 1.2e-193 682.9 Planctomycetes yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K19789 ko00000,ko03400 Bacteria 2J0ES@203682,COG1061@1,COG1061@2 NA|NA|NA L COGs COG1061 DNA or RNA helicase of superfamily II MAG.T2.48_02796 575540.Isop_2444 2.3e-107 396.7 Bacteria ko:K06919 ko00000 Bacteria COG3598@1,COG3598@2 NA|NA|NA L Psort location Cytoplasmic, score MAG.T2.48_02797 575540.Isop_2445 4.8e-185 654.1 Planctomycetes 2.1.1.72 ko:K07319 ko00000,ko01000,ko02048 Bacteria 2IY0Z@203682,COG0863@1,COG0863@2,COG1475@1,COG1475@2 NA|NA|NA KL ParB-like nuclease domain MAG.T2.48_02801 1403946.Q615_SPAC00131G0030 1.9e-08 64.7 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity MAG.T2.48_02805 575540.Isop_2452 4.3e-298 1030.4 Planctomycetes Bacteria 2IXN3@203682,COG5525@1,COG5525@2 NA|NA|NA S Phage terminase large subunit (GpA) MAG.T2.48_02807 1123247.AUIJ01000029_gene3181 2.5e-30 138.7 Alphaproteobacteria Bacteria 1RJ52@1224,2AUQT@1,2U6V7@28211,31KDR@2 NA|NA|NA MAG.T2.48_02809 575540.Isop_2435 1.4e-169 602.8 Planctomycetes B Bacteria 2IZFA@203682,COG5511@1,COG5511@2 NA|NA|NA S Phage portal protein, lambda family MAG.T2.48_02810 575540.Isop_2434 1.6e-128 466.8 Planctomycetes ftsZ ko:K01932,ko:K03531,ko:K03980 ko04112,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko02048,ko03036,ko04812 2.A.66.4 Bacteria 2IX3F@203682,COG3087@1,COG3087@2 NA|NA|NA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides MAG.T2.48_02811 1370121.AUWS01000080_gene750 1e-18 100.1 Bacteria Bacteria 28R8P@1,2ZDNC@2 NA|NA|NA MAG.T2.48_02812 331678.Cphamn1_0117 1.1e-95 356.7 Chlorobi 2.1.1.113 ko:K00590 ko00000,ko01000,ko02048 Bacteria 1FFNP@1090,COG0863@1,COG0863@2 NA|NA|NA H DNA methylase N-4 N-6 domain protein MAG.T2.48_02813 1968.JOEV01000010_gene1596 8.9e-32 144.1 Actinobacteria Bacteria 2B7HE@1,2H4D0@201174,320ME@2 NA|NA|NA MAG.T2.48_02815 756272.Plabr_3649 3.4e-112 412.5 Bacteria Bacteria COG3740@1,COG3740@2 NA|NA|NA OU Phage prohead protease, HK97 family MAG.T2.48_02816 575540.Isop_2444 1.5e-103 384.0 Bacteria ko:K06919 ko00000 Bacteria COG3598@1,COG3598@2 NA|NA|NA L Psort location Cytoplasmic, score MAG.T2.48_02818 1224318.DT73_09755 3.5e-29 136.7 Gammaproteobacteria Bacteria 1MV0C@1224,1RSUU@1236,COG1961@1,COG1961@2 NA|NA|NA L Recombinase MAG.T2.48_02819 575540.Isop_2433 2.5e-26 124.8 Planctomycetes Bacteria 2J1PT@203682,COG5471@1,COG5471@2 NA|NA|NA S Uncharacterized conserved protein (DUF2190) MAG.T2.48_02820 575540.Isop_2432 7.2e-20 103.6 Planctomycetes Bacteria 2ETQX@1,2J1E8@203682,33M8I@2 NA|NA|NA MAG.T2.48_02824 1210884.HG799462_gene8269 7.1e-08 63.9 Planctomycetes Bacteria 298NR@1,2J4Q1@203682,2ZVTA@2 NA|NA|NA MAG.T2.48_02825 575540.Isop_2427 1.4e-25 122.9 Planctomycetes Bacteria 2CBV8@1,2J0Q1@203682,335SS@2 NA|NA|NA MAG.T2.48_02827 575540.Isop_2430 5.4e-20 104.4 Planctomycetes Bacteria 2EQKH@1,2J1DT@203682,33I6I@2 NA|NA|NA MAG.T2.48_02828 575540.Isop_2425 1.8e-55 224.2 Planctomycetes Bacteria 2J1F5@203682,COG5283@1,COG5283@2 NA|NA|NA MAG.T2.48_02829 575540.Isop_2424 2.5e-51 209.1 Planctomycetes Bacteria 2DN68@1,2J012@203682,32UID@2 NA|NA|NA MAG.T2.48_02834 886293.Sinac_0717 1.4e-93 352.4 Planctomycetes Bacteria 2IY61@203682,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T2.48_02836 525897.Dbac_0889 1.1e-12 80.5 Desulfovibrionales Bacteria 1NAEJ@1224,2E3KB@1,2MFN6@213115,2WY3J@28221,32YIK@2,432FM@68525 NA|NA|NA MAG.T2.48_02837 521000.PROVRETT_07930 1e-64 254.2 Gammaproteobacteria Bacteria 1R441@1224,1S7QP@1236,COG0775@1,COG0775@2 NA|NA|NA F SEFIR domain MAG.T2.48_02839 530564.Psta_3730 4.6e-21 107.5 Planctomycetes yegJ Bacteria 2J1PD@203682,COG3779@1,COG3779@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2314) MAG.T2.48_02841 1122164.JHWF01000023_gene390 1.2e-55 224.2 Legionellales Bacteria 1JD6M@118969,1N01S@1224,1S0RI@1236,COG0457@1,COG0457@2 NA|NA|NA S COG0457 FOG TPR repeat MAG.T2.48_02842 1121936.AUHI01000016_gene108 1.4e-29 136.0 Firmicutes Bacteria 1W5V2@1239,28XTZ@1,2ZJQD@2 NA|NA|NA MAG.T2.48_02845 1123242.JH636434_gene3678 2e-59 235.3 Bacteria Bacteria COG2110@1,COG2110@2 NA|NA|NA P phosphatase homologous to the C-terminal domain of histone macroH2A1 MAG.T2.48_02846 1382306.JNIM01000001_gene1019 1.4e-98 366.7 Chloroflexi Bacteria 2G84N@200795,COG0154@1,COG0154@2 NA|NA|NA J Amidase MAG.T2.48_02847 1071679.BG57_06245 9.8e-07 60.8 Burkholderiaceae hemO 1.14.99.58 ko:K07215 ko00860,map00860 ko00000,ko00001,ko01000 Bacteria 1K5VK@119060,1N9VG@1224,2VVRM@28216,COG3230@1,COG3230@2 NA|NA|NA P Heme oxygenase MAG.T2.48_02848 555793.WSK_0647 3.6e-93 349.0 Sphingomonadales astD 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 R05049 RC00080 ko00000,ko00001,ko01000 Bacteria 1MV2I@1224,2K2Y7@204457,2TU8S@28211,COG1012@1,COG1012@2 NA|NA|NA C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate MAG.T2.48_02849 1184267.A11Q_2359 9.7e-62 244.2 Bdellovibrionales astA 1.2.1.71,2.3.1.109 ko:K00673,ko:K06447 ko00330,ko01100,map00330,map01100 R00832,R05049 RC00004,RC00064,RC00080 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_1875 Bacteria 1MWHC@1224,2MSRG@213481,2WPBD@28221,42SUP@68525,COG3138@1,COG3138@2 NA|NA|NA E Arginine N-succinyltransferase beta subunit MAG.T2.48_02850 756272.Plabr_4327 1.6e-101 376.7 Planctomycetes lat 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 ko:K00821,ko:K03918,ko:K07250,ko:K13524 ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727 M00016,M00027,M00028,M00845 R00457,R00908,R01648,R02283,R04188,R04475 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv3290c Bacteria 2IX55@203682,COG0160@1,COG0160@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T2.48_02851 595460.RRSWK_03050 5.8e-74 284.6 Planctomycetes apaH 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 2J0RZ@203682,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase MAG.T2.48_02852 1142394.PSMK_22160 7.4e-214 750.0 Planctomycetes guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2IX19@203682,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP MAG.T2.48_02854 1123355.JHYO01000008_gene2681 4.6e-15 87.8 Alphaproteobacteria rsbU 2.7.11.1,3.1.3.3 ko:K01079,ko:K04757,ko:K07315 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01001,ko01009,ko03021 Bacteria 1PFBR@1224,2U1RE@28211,COG2172@1,COG2172@2,COG2203@1,COG2203@2,COG2208@1,COG2208@2 NA|NA|NA T Sigma factor PP2C-like phosphatases MAG.T2.48_02855 1244869.H261_16957 1.7e-12 79.0 Alphaproteobacteria 2.4.1.187 ko:K04749,ko:K05946,ko:K06378 ko05111,map05111 ko00000,ko00001,ko01000,ko01003,ko03021 GT26 Bacteria 1N6U1@1224,2UFPK@28211,COG1366@1,COG1366@2 NA|NA|NA T Belongs to the anti-sigma-factor antagonist family MAG.T2.48_02856 1142394.PSMK_21940 3.1e-49 202.2 Planctomycetes ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IX01@203682,COG0767@1,COG0767@2 NA|NA|NA Q Belongs to the MlaE permease family MAG.T2.48_02861 314230.DSM3645_17685 1.5e-108 399.4 Planctomycetes mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1360 Bacteria 2IY7S@203682,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate MAG.T2.48_02862 1121920.AUAU01000005_gene982 3.4e-95 355.5 Acidobacteria ycaQ ko:K09927 ko00000 Bacteria 3Y96S@57723,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain MAG.T2.48_02865 1142394.PSMK_27360 5.5e-37 161.8 Planctomycetes Bacteria 2J0AW@203682,COG1253@1,COG1253@2 NA|NA|NA S COG1253 Hemolysins and related MAG.T2.48_02866 645512.GCWU000246_01886 5.6e-34 152.1 Synergistetes tlyC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06189 ko00000,ko02000 9.A.40.1.2 Bacteria 3T9V3@508458,COG1253@1,COG1253@2 NA|NA|NA P SMART CBS domain containing protein MAG.T2.48_02867 1158292.JPOE01000002_gene1568 3.5e-07 62.0 unclassified Burkholderiales hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 ko:K04082,ko:K05801 ko00000,ko03029,ko03110 Bacteria 1KKTV@119065,1RHZX@1224,2VSD5@28216,COG1076@1,COG1076@2 NA|NA|NA O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA MAG.T2.48_02868 1142394.PSMK_01710 1e-118 434.1 Planctomycetes ko:K02283,ko:K02454,ko:K03220,ko:K03466 ko03070,ko05111,map03070,map05111 M00331,M00332 ko00000,ko00001,ko00002,ko02035,ko02044,ko03036 3.A.12,3.A.15,3.A.6.1 Bacteria 2IXVD@203682,COG1716@1,COG1716@2,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.48_02873 1142394.PSMK_19560 2.5e-108 399.8 Planctomycetes ko:K02662 ko00000,ko02035,ko02044 Bacteria 2IWXB@203682,COG4972@1,COG4972@2 NA|NA|NA NU TIGRFAM type IV pilus assembly protein PilM MAG.T2.48_02874 344747.PM8797T_18856 4.8e-66 258.8 Planctomycetes ispH 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 2IY6M@203682,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 MAG.T2.48_02877 1121033.AUCF01000005_gene5320 9e-158 563.5 Rhodospirillales Bacteria 1MW20@1224,2JPHY@204441,2TQY4@28211,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T2.48_02879 1142394.PSMK_17790 5.8e-92 344.4 Planctomycetes ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IXFI@203682,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase MAG.T2.48_02880 1142394.PSMK_14460 1.3e-47 196.8 Planctomycetes nadK 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2IXD3@203682,COG0061@1,COG0061@2 NA|NA|NA H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP MAG.T2.48_02881 1142394.PSMK_11020 9.1e-134 483.8 Planctomycetes serS GO:0000049,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005524,GO:0008144,GO:0016597,GO:0017076,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0046983,GO:0070905,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IXGP@203682,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) MAG.T2.48_02882 452637.Oter_3587 7.4e-40 171.0 Opitutae sirR ko:K03709 ko00000,ko03000 Bacteria 3K8J0@414999,46T7C@74201,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor MAG.T2.48_02883 1131814.JAFO01000001_gene1620 7.7e-21 108.6 Alphaproteobacteria oprB ko:K07267 ko00000,ko02000 1.B.19.1 Bacteria 1QMC3@1224,2TU5Q@28211,COG3659@1,COG3659@2 NA|NA|NA M PFAM Carbohydrate-selective porin OprB MAG.T2.48_02884 595460.RRSWK_03060 1.3e-81 310.1 Planctomycetes troA GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K11707 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 2IXZP@203682,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family MAG.T2.48_02885 243090.RB12438 8.6e-89 333.6 Planctomycetes mntB ko:K11710 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 iYO844.BSU30760 Bacteria 2IYC3@203682,COG1121@1,COG1121@2 NA|NA|NA P COG1121 ABC-type Mn Zn transport systems ATPase component MAG.T2.48_02886 344747.PM8797T_06862 4.5e-91 342.0 Planctomycetes mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09819,ko:K11708 ko02010,map02010 M00243,M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 2IY19@203682,COG1108@1,COG1108@2,COG1321@1,COG1321@2 NA|NA|NA P COG1108 ABC-type Mn2 Zn2 transport systems permease MAG.T2.48_02887 344747.PM8797T_06867 6.4e-81 307.8 Planctomycetes mntD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09819,ko:K11709 ko02010,map02010 M00243,M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 2IWW2@203682,COG1108@1,COG1108@2,COG1321@1,COG1321@2 NA|NA|NA P COG1108 ABC-type Mn2 Zn2 transport systems permease MAG.T2.48_02888 1242864.D187_001730 3.4e-30 139.0 Bacteria ko:K08981 ko00000 Bacteria COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain MAG.T2.48_02889 1242864.D187_001731 4.3e-34 151.8 Bacteria ydbT ko:K08981 ko00000 Bacteria COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain MAG.T2.48_02893 1121877.JQKF01000010_gene710 2.9e-12 79.3 Actinobacteria Bacteria 2DMRS@1,2IQ7Q@201174,32T8Q@2 NA|NA|NA MAG.T2.48_02896 575540.Isop_2454 3.7e-40 171.4 Planctomycetes Bacteria 2IZU2@203682,COG3547@1,COG3547@2 NA|NA|NA L Protein of unknown function (DUF2924) MAG.T2.48_02898 1122164.JHWF01000006_gene240 2.9e-96 359.4 Legionellales cueO Bacteria 1JDVG@118969,1MU0J@1224,1RQ4N@1236,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase MAG.T2.48_02899 335543.Sfum_3255 3.7e-18 98.6 Syntrophobacterales Bacteria 1RJNV@1224,2MRXW@213462,2WQ1R@28221,42TNF@68525,COG2020@1,COG2020@2 NA|NA|NA O Isoprenylcysteine carboxyl methyltransferase (ICMT) family MAG.T2.48_02900 1123242.JH636438_gene5714 2.1e-37 162.2 Planctomycetes ko:K07071 ko00000 Bacteria 2J0FI@203682,COG4276@1,COG4276@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport MAG.T2.48_02902 1142394.PSMK_01110 4.6e-115 421.4 Planctomycetes splB 4.1.99.14 ko:K03716 ko00000,ko01000 Bacteria 2IX0U@203682,COG1533@1,COG1533@2 NA|NA|NA L Radical SAM MAG.T2.48_02904 1500281.JQKZ01000022_gene841 8.5e-14 83.6 Chryseobacterium Bacteria 1IKYU@117743,2DSUT@1,33HH9@2,3ZSBM@59732,4PQ2D@976 NA|NA|NA MAG.T2.48_02905 1265313.HRUBRA_01076 6.6e-55 220.3 unclassified Gammaproteobacteria tadA 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 Bacteria 1JB8J@118884,1RE8P@1224,1S3V3@1236,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase MAG.T2.48_02906 448385.sce3760 3.2e-70 272.3 Myxococcales wbpP 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU7J@1224,2WJCH@28221,2YZUS@29,42MRN@68525,COG0451@1,COG0451@2 NA|NA|NA M Polysaccharide biosynthesis protein MAG.T2.48_02907 1123508.JH636442_gene4086 2.3e-79 302.8 Planctomycetes desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2IZ45@203682,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase MAG.T2.48_02908 1142394.PSMK_01990 1.8e-191 675.6 Planctomycetes atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2IXN5@203682,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit MAG.T2.48_02909 1142394.PSMK_01980 1.5e-21 109.8 Planctomycetes atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2J09A@203682,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T2.48_02910 1236504.HMPREF2132_10775 6.5e-08 64.3 Bacteroidia atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 Bacteria 2FQWH@200643,4NQKA@976,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T2.48_02911 1077285.AGDG01000032_gene4226 1.5e-12 79.0 Bacteroidaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01165 Bacteria 2FTSZ@200643,4ARQC@815,4NURW@976,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T2.48_02912 1142394.PSMK_01950 1.2e-33 150.6 Planctomycetes atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2IZP5@203682,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane MAG.T2.48_02917 1142394.PSMK_11640 1.2e-52 213.0 Planctomycetes nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00338,ko:K02573 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IZAI@203682,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.48_02918 1123508.JH636447_gene7857 2.9e-07 65.5 Planctomycetes Bacteria 2IZ0P@203682,COG2931@1,COG2931@2,COG3291@1,COG3291@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) MAG.T2.48_02919 1379698.RBG1_1C00001G1527 1.3e-48 201.8 unclassified Bacteria 3.4.21.66 ko:K08651 ko00000,ko01000,ko01002,ko03110 Bacteria 2NPDC@2323,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 MAG.T2.48_02920 522306.CAP2UW1_0334 6.7e-40 173.7 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T2.48_02922 70448.A0A090M683 2.6e-22 113.6 Eukaryota Eukaryota 28JEB@1,2QRTB@2759 NA|NA|NA S FG-GAP repeat MAG.T2.48_02925 1242864.D187_006689 3.4e-27 129.8 Proteobacteria GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 ko:K06955 ko00000 Bacteria 1R5C0@1224,COG3380@1,COG3380@2 NA|NA|NA S Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers MAG.T2.48_02926 575540.Isop_2143 5.6e-45 187.2 Planctomycetes Bacteria 2DGKH@1,2J55R@203682,2ZWDA@2 NA|NA|NA MAG.T2.48_02927 42256.RradSPS_1152 3.6e-25 121.3 Actinobacteria Bacteria 2B5Y2@1,2H193@201174,31YU2@2 NA|NA|NA MAG.T2.48_02928 1267534.KB906758_gene2500 1.4e-14 88.2 Bacteria Bacteria COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T2.48_02929 1210884.HG799464_gene11142 4e-80 305.1 Planctomycetes desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2IZ45@203682,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase MAG.T2.48_02933 521674.Plim_0989 2e-91 344.0 Planctomycetes traC Bacteria 2J0Z2@203682,COG0714@1,COG0714@2,COG4643@1,COG4643@2 NA|NA|NA S Protein of unknown function (DUF3987) MAG.T2.48_02934 344747.PM8797T_17102 1.2e-51 210.7 Planctomycetes ko:K03733 ko00000,ko03036 Bacteria 2IZWA@203682,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.48_02937 314230.DSM3645_22566 2.7e-29 135.6 Planctomycetes nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IZMU@203682,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) MAG.T2.48_02939 530564.Psta_4551 5.2e-77 294.3 Planctomycetes livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IYQW@203682,COG0410@1,COG0410@2 NA|NA|NA E ABC transporter MAG.T2.48_02940 1210884.HG799465_gene11945 2.5e-75 289.3 Planctomycetes livG ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IX2P@203682,COG0411@1,COG0411@2 NA|NA|NA E Branched-chain amino acid ATP-binding cassette transporter MAG.T2.48_02941 530564.Psta_4549 2.7e-71 275.8 Planctomycetes livM ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IYM8@203682,COG4177@1,COG4177@2 NA|NA|NA E Branched-chain amino acid transport system / permease component MAG.T2.48_02942 1210884.HG799465_gene11947 9.2e-88 330.5 Planctomycetes ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IWS7@203682,COG0559@1,COG0559@2 NA|NA|NA E Branched-chain amino acid transport system / permease component MAG.T2.48_02943 530564.Psta_4547 2e-116 426.0 Planctomycetes ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IYKT@203682,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region MAG.T2.48_02944 1142394.PSMK_01780 1.2e-52 214.2 Planctomycetes lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 Bacteria 2IXXN@203682,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.48_02945 370438.PTH_1049 1.1e-168 600.1 Peptococcaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,247Z3@186801,260AT@186807,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) MAG.T2.48_02946 861299.J421_3590 6.9e-91 340.9 Gemmatimonadetes trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 1ZTEH@142182,COG0492@1,COG0492@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase MAG.T2.48_02948 344747.PM8797T_05890 2.8e-122 445.3 Planctomycetes ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2IXPP@203682,COG0686@1,COG0686@2 NA|NA|NA C Belongs to the AlaDH PNT family MAG.T2.48_02949 1142394.PSMK_02980 1.6e-117 429.9 Planctomycetes purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 Bacteria 2IX58@203682,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family MAG.T2.48_02950 314265.R2601_20696 4.7e-12 80.9 Alphaproteobacteria ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1R5H7@1224,2UEP3@28211,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T2.48_02952 1356852.N008_11050 5.7e-63 247.7 Cytophagia dedA ko:K03975 ko00000 Bacteria 47NAX@768503,4NHQA@976,COG0586@1,COG0586@2 NA|NA|NA S PFAM SNARE associated Golgi protein MAG.T2.48_02953 1142394.PSMK_22310 1.5e-116 426.4 Planctomycetes sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXQU@203682,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit MAG.T2.48_02954 706587.Desti_2333 3e-35 155.6 Deltaproteobacteria gph1 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1P1EG@1224,2WWM2@28221,431YQ@68525,COG0546@1,COG0546@2 NA|NA|NA S HAD-hyrolase-like MAG.T2.48_02955 1142394.PSMK_20590 8.4e-54 217.2 Planctomycetes Bacteria 2CB5F@1,2IXTM@203682,2ZCDM@2 NA|NA|NA MAG.T2.48_02959 1387312.BAUS01000004_gene1446 1.1e-97 363.2 Betaproteobacteria yhaZ Bacteria 1P0C1@1224,2VISN@28216,COG4335@1,COG4335@2 NA|NA|NA L DNA alkylation repair MAG.T2.48_02960 633147.Olsu_1111 2.4e-28 132.5 Coriobacteriia tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 2GJVT@201174,4CVCW@84998,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J MAG.T2.48_02961 1142394.PSMK_20610 3.8e-69 268.5 Planctomycetes cdsA2 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748,ko:K09949 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 Bacteria 2IXGX@203682,COG3494@1,COG3494@2 NA|NA|NA S Protein of unknown function (DUF1009) MAG.T2.48_02962 1121448.DGI_0783 6.6e-39 167.5 Desulfovibrionales yvdD_1 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1RD59@1224,2MAYK@213115,2WNMI@28221,42SVS@68525,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T2.48_02963 1142394.PSMK_29820 3.6e-64 252.3 Planctomycetes 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2IXB8@203682,COG0472@1,COG0472@2 NA|NA|NA M PFAM Glycosyl transferase family 4 MAG.T2.48_02964 886293.Sinac_1306 1.5e-08 68.6 Planctomycetes Bacteria 2IZXM@203682,COG0457@1,COG0457@2,COG3307@1,COG3307@2 NA|NA|NA M PFAM O-Antigen MAG.T2.48_02965 1142394.PSMK_22080 7.3e-102 378.3 Planctomycetes dsbD 1.8.1.8 ko:K04084,ko:K08344 ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.5 Bacteria 2IXJF@203682,COG4232@1,COG4232@2 NA|NA|NA CO Cytochrome c biogenesis protein transmembrane region MAG.T2.48_02966 1142394.PSMK_19810 7.5e-77 294.3 Planctomycetes fliM ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 Bacteria 2IY74@203682,COG1868@1,COG1868@2 NA|NA|NA N flagellar motor switch protein MAG.T2.48_02967 1142394.PSMK_13860 1.7e-142 512.7 Planctomycetes nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 2IWY3@203682,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination MAG.T2.48_02968 1142394.PSMK_13870 5.5e-195 688.3 Planctomycetes infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2IXYU@203682,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex MAG.T2.48_02970 1142394.PSMK_13900 1.4e-19 104.8 Bacteria nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T2.48_02971 358220.C380_04890 2.4e-13 85.1 Comamonadaceae Bacteria 1MYB8@1224,2VI6C@28216,4ABFF@80864,COG0457@1,COG0457@2 NA|NA|NA S SMART Tetratricopeptide domain protein MAG.T2.48_02972 266117.Rxyl_1318 5.3e-61 241.1 Rubrobacteria yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2GJ4G@201174,4CPAM@84995,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulator MAG.T2.48_02974 1192034.CAP_3742 9.4e-190 669.8 Myxococcales icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Bacteria 1MW3J@1224,2WJ8W@28221,2YYDJ@29,42M56@68525,COG0538@1,COG0538@2 NA|NA|NA C Isocitrate/isopropylmalate dehydrogenase MAG.T2.48_02976 314345.SPV1_13679 3.8e-49 201.1 Proteobacteria Bacteria 1RAPV@1224,28TYB@1,2ZG4Y@2 NA|NA|NA S Domain of unknown function (DUF4145) MAG.T2.48_02977 96561.Dole_2506 2.7e-134 485.3 delta/epsilon subdivisions Bacteria 1PE61@1224,431F8@68525,COG0515@1,COG0515@2 NA|NA|NA KLT Serine Threonine protein kinase MAG.T2.48_02979 69042.WH5701_04165 1.1e-271 942.2 Synechococcus hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1G0GY@1117,1GZ79@1129,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain MAG.T2.48_02980 1509405.GV67_19470 8e-42 177.2 Rhizobiaceae Bacteria 1MWFQ@1224,2U8F9@28211,4BMX4@82115,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family MAG.T2.48_02981 1337936.IJ00_10200 8.2e-16 90.9 Nostocales Bacteria 1GEDZ@1117,1HRT4@1161,2FAQN@1,342Y2@2 NA|NA|NA MAG.T2.48_02982 1267533.KB906738_gene2239 3.3e-98 365.5 Acidobacteriia 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JHVD@204432,3Y2K5@57723,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T2.48_02983 394221.Mmar10_1098 5.8e-90 338.6 Hyphomonadaceae thrA GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4,4.1.1.20 ko:K00003,ko:K00928,ko:K12524,ko:K12525,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00451,R00480,R01773,R01775 RC00002,RC00043,RC00087,RC00299 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_0002,iEcDH1_1363.EcDH1_3594,iSFV_1184.SFV_0001,iUMNK88_1353.UMNK88_4778,iYL1228.KPN_04234 Bacteria 1MUDC@1224,2TQWS@28211,43WRR@69657,COG0460@1,COG0460@2,COG0527@1,COG0527@2 NA|NA|NA E homoserine dehydrogenase MAG.T2.48_02984 248742.XP_005647031.1 2e-95 356.3 Chlorophyta CBL GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019346,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0050667,GO:0070279,GO:0071265,GO:0071266,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 iRC1080.CRv4_Au5_s16_g6444_t1 Viridiplantae 34JPF@3041,37HJ8@33090,COG0626@1,KOG0053@2759 NA|NA|NA E cystathionine beta-lyase MAG.T2.48_02985 521674.Plim_3918 4.8e-258 896.7 Planctomycetes Bacteria 2IYY0@203682,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1214) MAG.T2.48_02986 861299.J421_1087 9.5e-09 67.0 Bacteria Bacteria 2BHPS@1,32BT1@2 NA|NA|NA MAG.T2.48_02987 237368.SCABRO_01739 3.3e-12 80.1 Planctomycetes Bacteria 2DBYC@1,2IZ15@203682,2ZBUF@2 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T2.48_02988 1192034.CAP_7232 2.8e-41 175.6 Myxococcales mtfA ko:K09933 ko00000,ko01002 Bacteria 1RAHF@1224,2WUIA@28221,2YV7F@29,42QKQ@68525,COG3228@1,COG3228@2 NA|NA|NA S Belongs to the MtfA family MAG.T2.48_02989 595460.RRSWK_02582 2e-66 260.4 Planctomycetes ko:K13963 ko05146,map05146 ko00000,ko00001 Bacteria 2J2TV@203682,COG4826@1,COG4826@2 NA|NA|NA O SERine Proteinase INhibitors MAG.T2.48_02990 314254.OA2633_12730 8.6e-95 354.4 Hyphomonadaceae 5.4.3.2 ko:K01843 ko00310,map00310 R00461 RC00303 ko00000,ko00001,ko01000 Bacteria 1MUPJ@1224,2U1WH@28211,440RX@69657,COG1509@1,COG1509@2 NA|NA|NA E 4Fe-4S single cluster domain MAG.T2.48_02991 1121918.ARWE01000001_gene2379 3e-93 348.2 Deltaproteobacteria pcaI 2.8.3.6 ko:K01031 ko00362,ko01100,ko01120,map00362,map01100,map01120 R02990 RC00014 ko00000,ko00001,ko01000 Bacteria 1MVEI@1224,2WMDH@28221,42QMC@68525,COG1788@1,COG1788@2 NA|NA|NA I 3-oxoacid CoA-transferase MAG.T2.48_02992 1121918.ARWE01000001_gene2378 3.6e-88 331.3 Deltaproteobacteria pcaJ 2.8.3.6 ko:K01032 ko00362,ko01100,ko01120,map00362,map01100,map01120 R02990 RC00014 ko00000,ko00001,ko01000 Bacteria 1RA4V@1224,2WJ9V@28221,42PZY@68525,COG2057@1,COG2057@2 NA|NA|NA I Acyl CoA acetate 3-ketoacid CoA transferase beta subunit MAG.T2.48_02993 458817.Shal_2957 1.7e-153 549.3 Shewanellaceae 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MUY5@1224,1SM2G@1236,2QAAP@267890,COG0001@1,COG0001@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T2.48_02994 1382306.JNIM01000001_gene329 3.9e-141 508.1 Chloroflexi pcaF 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K00632,ko:K02615 ko00071,ko00072,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00360,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095,R09839 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2G5YW@200795,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T2.48_02996 525257.HMPREF0204_12361 7e-34 151.8 Chryseobacterium CP_1075 Bacteria 1IIHW@117743,3ZQ5Q@59732,4NRK6@976,COG2273@1,COG2273@2,COG5563@1,COG5563@2 NA|NA|NA G endonuclease I MAG.T2.48_02997 411471.SUBVAR_06509 1.2e-10 75.5 Ruminococcaceae ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 1TQ0K@1239,24AVI@186801,3WJSD@541000,COG4219@1,COG4219@2,COG4942@1,COG4942@2 NA|NA|NA KT Peptidase, M56 MAG.T2.48_02998 344747.PM8797T_13243 1.3e-18 99.4 Bacteria Bacteria COG3682@1,COG3682@2 NA|NA|NA K negative regulation of transcription, DNA-templated MAG.T2.48_02999 41431.PCC8801_4097 1.8e-69 270.8 Cyanobacteria 3.2.1.8 ko:K01181 ko00000,ko01000 Bacteria 1GGBS@1117,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase MAG.T2.48_03002 1123242.JH636434_gene4482 2.3e-62 247.3 Bacteria gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria COG1450@1,COG1450@2 NA|NA|NA NU protein transport across the cell outer membrane MAG.T2.48_03003 1125863.JAFN01000001_gene2969 9.1e-108 397.5 Deltaproteobacteria gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MU7V@1224,2WIPP@28221,42M51@68525,COG2804@1,COG2804@2 NA|NA|NA NU PFAM Type II secretion system protein E MAG.T2.48_03004 1112217.PPL19_12838 5.2e-26 125.9 Gammaproteobacteria pilC GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1MV4U@1224,1RNV0@1236,COG1459@1,COG1459@2 NA|NA|NA U type II secretion system MAG.T2.48_03005 1245471.PCA10_50040 9.8e-22 110.2 Pseudomonas aeruginosa group gspG2 ko:K02246,ko:K02456,ko:K02457,ko:K02458 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1RDX2@1224,1S69B@1236,1YJG1@136841,COG2165@1,COG2165@2 NA|NA|NA NU Type II secretion system (T2SS), protein G MAG.T2.48_03013 314230.DSM3645_15325 8.9e-95 354.0 Planctomycetes Bacteria 2J4TW@203682,COG4924@1,COG4924@2 NA|NA|NA S Uncharacterized protein conserved in bacteria C-term(DUF2220) MAG.T2.48_03014 314230.DSM3645_15320 6.7e-263 914.1 Planctomycetes Bacteria 2J34J@203682,COG4913@1,COG4913@2 NA|NA|NA S Putative exonuclease SbcCD, C subunit MAG.T2.48_03015 314230.DSM3645_15315 4e-49 201.4 Bacteria Bacteria 2CB46@1,31GHU@2 NA|NA|NA S Domain of unknown function (DUF4194) MAG.T2.48_03016 314230.DSM3645_15310 2.3e-127 462.6 Bacteria Bacteria COG4942@1,COG4942@2 NA|NA|NA D peptidase MAG.T2.48_03022 864051.BurJ1DRAFT_1894 2.8e-50 205.3 Bacteria 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T2.48_03023 1178825.ALIH01000002_gene973 7.7e-43 179.9 Flavobacteriia MA20_06535 Bacteria 1I2BQ@117743,4NPT7@976,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP MAG.T2.48_03026 1142394.PSMK_28440 8.2e-129 467.2 Planctomycetes nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXB1@203682,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate MAG.T2.48_03029 1142394.PSMK_07920 1e-34 154.1 Planctomycetes ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2IZ7X@203682,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol MAG.T2.48_03030 886293.Sinac_1523 1.3e-156 560.1 Planctomycetes pepF ko:K08602 ko00000,ko01000,ko01002 Bacteria 2IYTJ@203682,COG1164@1,COG1164@2 NA|NA|NA E TIGRFAM oligoendopeptidase, M3 family MAG.T2.48_03031 1292034.OR37_02353 7.2e-107 394.0 Caulobacterales lysDH 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY1G@1224,2KHR6@204458,2TU0J@28211,COG1748@1,COG1748@2 NA|NA|NA E Saccharopine dehydrogenase C-terminal domain MAG.T2.48_03032 926550.CLDAP_30940 4.8e-158 564.7 Chloroflexi ddc 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2G7N6@200795,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain MAG.T2.48_03033 1089549.AZUQ01000001_gene1613 1.9e-65 255.8 Glycomycetales Bacteria 2GPB4@201174,4EZ6I@85014,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family MAG.T2.48_03034 498761.HM1_0407 4e-27 129.0 Clostridia ko:K07098 ko00000 Bacteria 1UU17@1239,25CIK@186801,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T2.48_03036 744872.Spica_2859 5.5e-17 94.4 Spirochaetes yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 ko:K15034 ko00000,ko03012 Bacteria 2J8DU@203691,COG1186@1,COG1186@2 NA|NA|NA J PFAM Class I peptide chain release factor MAG.T2.48_03038 376686.Fjoh_2054 1.7e-09 70.5 Bacteria Bacteria COG1372@1,COG1372@2 NA|NA|NA L intein-mediated protein splicing MAG.T2.48_03039 85643.Tmz1t_3179 3.7e-190 671.4 Rhodocyclales yfjM Bacteria 1R5X1@1224,2KZMY@206389,2VQ73@28216,COG1479@1,COG1479@2,COG3472@1,COG3472@2 NA|NA|NA S Protein of unknown function DUF262 MAG.T2.48_03040 525903.Taci_1498 1.1e-12 79.0 Synergistetes ko:K02806 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 Bacteria 3TCF2@508458,COG3311@1,COG3311@2 NA|NA|NA L TIGRFAM DNA binding domain protein, excisionase family MAG.T2.48_03041 1158762.KB898043_gene1012 0.0 1085.5 Chromatiales hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,1RMRA@1236,1WVVZ@135613,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain MAG.T2.48_03042 443144.GM21_0429 8.4e-91 340.9 Deltaproteobacteria hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1RHRY@1224,2WPTG@28221,42SEC@68525,COG0732@1,COG0732@2 NA|NA|NA L PFAM restriction modification system DNA specificity domain MAG.T2.48_03043 1269813.ATUL01000015_gene117 0.0 1492.6 Gammaproteobacteria hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1MU96@1224,1RP2Q@1236,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification MAG.T2.48_03044 459495.SPLC1_S531840 5.9e-70 270.8 Oscillatoriales ko:K07043 ko00000 Bacteria 1G4YB@1117,1HDXD@1150,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 MAG.T2.48_03048 671143.DAMO_2725 5.7e-14 83.2 Bacteria ko:K07172,ko:K18842 ko00000,ko02048 Bacteria COG2336@1,COG2336@2 NA|NA|NA T PFAM SpoVT AbrB MAG.T2.48_03049 715226.ABI_41910 5.3e-19 103.6 Bacteria ko:K13277,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria COG4257@1,COG4257@2 NA|NA|NA V antibiotic catabolic process MAG.T2.48_03050 497964.CfE428DRAFT_6631 1e-40 174.5 Bacteria ko:K14274,ko:K20276 ko00040,ko02024,map00040,map02024 R02427 RC00713 ko00000,ko00001,ko01000 Bacteria COG3386@1,COG3386@2,COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T2.48_03054 272123.Anacy_0456 2.9e-19 101.7 Nostocales vapC Bacteria 1GKNT@1117,1HSMZ@1161,COG4113@1,COG4113@2 NA|NA|NA S PIN domain MAG.T2.48_03055 626887.J057_16165 1.7e-37 162.9 Gammaproteobacteria Bacteria 1RDDZ@1224,1S277@1236,COG2865@1,COG2865@2 NA|NA|NA MAG.T2.48_03057 861299.J421_1503 6.1e-35 154.1 Gemmatimonadetes Bacteria 1ZU0D@142182,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T2.48_03058 1116472.MGMO_20c00060 3e-50 204.5 Methylococcales Bacteria 1MZWT@1224,1T747@1236,1XGP9@135618,2D8VC@1,32TS1@2 NA|NA|NA MAG.T2.48_03060 1128421.JAGA01000002_gene1136 2.3e-44 185.3 unclassified Bacteria Bacteria 2NQX2@2323,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T2.48_03061 379066.GAU_0081 1e-35 156.0 Gemmatimonadetes Bacteria 1ZV8M@142182,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T2.48_03062 379066.GAU_0082 2e-64 251.9 Bacteria Bacteria COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity MAG.T2.48_03063 1385515.N791_10920 7.3e-46 189.9 Gammaproteobacteria Bacteria 1N57Z@1224,1SFU9@1236,COG2764@1,COG2764@2 NA|NA|NA S glyoxalase bleomycin resistance protein dioxygenase MAG.T2.48_03064 102232.GLO73106DRAFT_00023250 4.3e-24 119.0 Bacteria Bacteria 2DNTV@1,32Z41@2 NA|NA|NA MAG.T2.48_03065 1267535.KB906767_gene637 4.4e-185 654.4 Acidobacteria yedY ko:K07147 ko00000,ko01000 Bacteria 3Y3AI@57723,COG2041@1,COG2041@2,COG4117@1,COG4117@2 NA|NA|NA C Oxidoreductase molybdopterin binding domain MAG.T2.48_03066 1163409.UUA_18219 1.3e-78 300.1 Gammaproteobacteria Bacteria 1RGPG@1224,1T3Q2@1236,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T2.48_03067 1128421.JAGA01000002_gene875 2.3e-86 325.1 unclassified Bacteria Bacteria 2NRFC@2323,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain MAG.T2.48_03068 1123508.JH636451_gene6006 2.5e-60 238.0 Planctomycetes Bacteria 2J2FF@203682,COG5649@1,COG5649@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T2.48_03070 1163408.UU9_13383 1.6e-40 172.6 Gammaproteobacteria adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1RK1A@1224,1SZQY@1236,COG0563@1,COG0563@2 NA|NA|NA F AAA domain MAG.T2.48_03075 1120959.ATXF01000005_gene1448 2e-37 162.5 Microbacteriaceae Bacteria 2IN0C@201174,4FKDA@85023,COG2020@1,COG2020@2 NA|NA|NA O Phospholipid methyltransferase MAG.T2.48_03076 1523503.JPMY01000010_gene2773 3.3e-10 71.6 Proteobacteria secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1P9KU@1224,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T2.48_03077 378806.STAUR_0352 5.7e-61 241.5 Myxococcales Bacteria 1PPKI@1224,2X9W2@28221,2Z1KJ@29,43A74@68525,COG0500@1,COG2226@2 NA|NA|NA Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MAG.T2.48_03078 870187.Thini_3083 2.4e-45 189.1 Gammaproteobacteria yafK Bacteria 1MXY6@1224,1RPXT@1236,COG3034@1,COG3034@2 NA|NA|NA S ErfK YbiS YcfS YnhG family protein MAG.T2.48_03079 575540.Isop_2454 6.5e-36 157.1 Planctomycetes Bacteria 2IZU2@203682,COG3547@1,COG3547@2 NA|NA|NA L Protein of unknown function (DUF2924) MAG.T2.48_03080 575540.Isop_2455 1.1e-93 349.7 Planctomycetes ko:K06400 ko00000 Bacteria 2IYJH@203682,COG1961@1,COG1961@2 NA|NA|NA L Site-specific recombinase, DNA invertase Pin MAG.T2.48_03081 240016.ABIZ01000001_gene885 1.4e-77 297.0 Bacteria Bacteria COG1409@1,COG1409@2 NA|NA|NA S acid phosphatase activity MAG.T2.48_03082 1280001.BAOA01000157_gene4752 3.5e-82 312.0 Vibrionales rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1MUEF@1224,1RMMB@1236,1XSIW@135623,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit MAG.T2.48_03083 1541065.JRFE01000050_gene2947 1.5e-41 176.0 Pleurocapsales 2.3.1.189 ko:K15520 ko00000,ko01000 Bacteria 1GCIE@1117,3VKF6@52604,COG0454@1,COG0456@2 NA|NA|NA K PFAM Acetyltransferase (GNAT) family MAG.T2.48_03084 1123242.JH636434_gene5201 1e-07 62.8 Bacteria Bacteria COG4453@1,COG4453@2 NA|NA|NA K Protein conserved in bacteria MAG.T2.48_03085 1232410.KI421426_gene1398 5.1e-182 644.4 Desulfuromonadales Bacteria 1MWP2@1224,2WPCI@28221,42SMD@68525,43U6S@69541,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T2.48_03086 420324.KI911985_gene5107 1.7e-19 101.7 Methylobacteriaceae Bacteria 1JV63@119045,1MWFQ@1224,2TUZG@28211,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family MAG.T2.48_03087 761193.Runsl_3914 1.1e-10 74.3 Cytophagia Bacteria 2EQ7Y@1,33HU6@2,47WEW@768503,4NXWG@976 NA|NA|NA MAG.T2.48_03088 69042.WH5701_04205 0.0 1435.2 Synechococcus 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1G3YH@1117,1GZJQ@1129,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification MAG.T2.48_03090 946483.Cenrod_2251 2.4e-16 91.3 Bacteria ko:K07726,ko:K13655 ko00000,ko02048,ko03000 Bacteria COG2944@1,COG2944@2 NA|NA|NA K sequence-specific DNA binding MAG.T2.48_03091 1304885.AUEY01000096_gene2839 2.5e-177 629.0 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity MAG.T2.48_03092 45351.EDO29185 2.1e-20 104.8 Eukaryota SRR GO:0000166,GO:0000287,GO:0002237,GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005509,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008721,GO:0009058,GO:0009069,GO:0009070,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010033,GO:0010243,GO:0014070,GO:0014072,GO:0016020,GO:0016043,GO:0016053,GO:0016594,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017076,GO:0017144,GO:0018114,GO:0019752,GO:0019842,GO:0019904,GO:0022607,GO:0030165,GO:0030170,GO:0030378,GO:0030554,GO:0031406,GO:0032496,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033993,GO:0035639,GO:0036094,GO:0036361,GO:0036477,GO:0042165,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0042866,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043207,GO:0043278,GO:0043279,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044297,GO:0044424,GO:0044444,GO:0044464,GO:0045177,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0048513,GO:0048731,GO:0048856,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051704,GO:0051707,GO:0060322,GO:0060359,GO:0065003,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072347,GO:0097159,GO:0097367,GO:0097458,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901700 2.7.10.2,4.3.1.19,5.1.1.18 ko:K01754,ko:K12235,ko:K17538,ko:K21851 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00589,R00996 RC00302,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko01001,ko04131 Eukaryota COG1171@1,KOG1251@2759 NA|NA|NA E serine racemase MAG.T2.48_03093 639030.JHVA01000001_gene3482 2.6e-44 186.8 Acidobacteriia Bacteria 2JHIN@204432,3Y31A@57723,COG3391@1,COG3391@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T2.48_03098 1205680.CAKO01000027_gene4745 2.8e-90 337.8 Proteobacteria phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1RG4D@1224,COG0415@1,COG0415@2 NA|NA|NA L PFAM DNA photolyase, FAD-binding MAG.T2.48_03099 1205680.CAKO01000027_gene4746 1.9e-195 688.3 Rhodospirillales ko:K13574 ko00000,ko01000 Bacteria 1MWQY@1224,2JV8F@204441,2TR37@28211,COG2055@1,COG2055@2 NA|NA|NA C Malate/L-lactate dehydrogenase MAG.T2.48_03100 1205680.CAKO01000027_gene4747 2.6e-71 274.6 Alphaproteobacteria MA20_43565 Bacteria 1MUF8@1224,2TTNG@28211,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T2.48_03101 228410.NE2030 1.3e-30 138.7 Nitrosomonadales glgC GO:0000166,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016043,GO:0016051,GO:0016208,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0022607,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046872,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_3027,iUTI89_1310.UTI89_C3939,iYL1228.KPN_03796 Bacteria 1MVTC@1224,2VIP2@28216,372V3@32003,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans MAG.T2.48_03109 983917.RGE_34080 2.3e-74 285.0 unclassified Burkholderiales livM ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1KJ88@119065,1MV66@1224,2VH43@28216,COG4177@1,COG4177@2 NA|NA|NA E Belongs to the binding-protein-dependent transport system permease family # 2275 queries scanned # Total time (seconds): 23.1435070038 # Rate: 98.30 q/s