# emapper version: emapper-hotfix-numpy-45-g001c4bf emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share_mix/Bin_all/emapper//MAG.T2.42/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share_mix/Bin_all/Bin_prokka//MAG.T2.42/MAG.T2.42.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share_mix/Bin_all/emapper//MAG.T2.42/MAG.T2.42 --usemem --override # time: Sat Jun 6 08:09:15 2026 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. MAG.T2.42_00004 314230.DSM3645_05525 1.2e-102 381.7 Planctomycetes addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 2IX1B@203682,COG1074@1,COG1074@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily MAG.T2.42_00005 314230.DSM3645_05530 1.2e-74 288.5 Planctomycetes addB 3.1.11.5,3.6.4.12 ko:K01144,ko:K02259,ko:K16899 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko01000,ko03029,ko03400 3.D.4.4 Bacteria 2IYGU@203682,COG2887@1,COG2887@2,COG3893@1,COG3893@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily MAG.T2.42_00008 1142394.PSMK_03120 5.4e-136 491.1 Planctomycetes 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IX8X@203682,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T2.42_00009 1142394.PSMK_03130 7.8e-103 380.9 Planctomycetes 2.3.1.179,2.3.1.235,2.3.1.260 ko:K05551,ko:K09458 ko00061,ko00253,ko00780,ko01056,ko01100,ko01130,ko01212,map00061,map00253,map00780,map01056,map01100,map01130,map01212 M00083,M00572,M00778 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R06635,R06637,R06641,R06643,R06644,R06645,R07762,R09258,R09259,R10115,R10119,R10960,R11516 RC00004,RC00039,RC02545,RC02728,RC02729,RC02888,RC02931,RC02932,RC02947 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Bacteria 2IY1N@203682,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T2.42_00010 1211114.ALIP01000127_gene572 8.7e-176 623.2 Xanthomonadales dhs1 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUWF@1224,1RRMM@1236,1X2YX@135614,COG3200@1,COG3200@2 NA|NA|NA E phospho-2-dehydro-3-deoxyheptonate aldolase MAG.T2.42_00013 1123277.KB893172_gene856 7.6e-89 334.0 Cytophagia 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47M10@768503,4NG0V@976,COG3622@1,COG3622@2 NA|NA|NA G Belongs to the hyi family MAG.T2.42_00016 234267.Acid_6565 6.1e-90 337.8 Acidobacteria 3.1.1.17 ko:K01053,ko:K13735 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05100,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map05100 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 3Y6WN@57723,COG3386@1,COG3386@2 NA|NA|NA G PFAM SMP-30 Gluconolaconase MAG.T2.42_00017 1499967.BAYZ01000068_gene1935 3.4e-15 90.5 unclassified Bacteria ko:K12685,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000,ko02044 1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2NS5M@2323,COG3266@1,COG3266@2,COG3420@1,COG3420@2,COG4733@1,COG4733@2 NA|NA|NA P Fibronectin type 3 domain MAG.T2.42_00018 1142394.PSMK_04940 4.5e-29 135.2 Bacteria 3.5.1.28 ko:K01448,ko:K07273 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria COG5632@1,COG5632@2 NA|NA|NA M N-Acetylmuramoyl-L-alanine amidase MAG.T2.42_00020 240015.ACP_3331 5e-18 97.4 Acidobacteriia Bacteria 29E6W@1,2JJ83@204432,3014W@2,3Y4JR@57723 NA|NA|NA MAG.T2.42_00022 1142394.PSMK_10690 1.5e-93 349.7 Planctomycetes galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY22@203682,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family MAG.T2.42_00023 91464.S7335_4149 5.9e-21 107.8 Cyanobacteria pagN ko:K12980 ko00000,ko01005 Bacteria 1GDS8@1117,COG3637@1,COG3637@2 NA|NA|NA M Lipid A 3-O-deacylase (PagL) MAG.T2.42_00024 1192034.CAP_6382 6.6e-50 204.1 Myxococcales 1.2.5.3,1.3.99.16 ko:K03518,ko:K07302,ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 Bacteria 1RD8C@1224,2WV9K@28221,2Z3A1@29,4309M@68525,COG2080@1,COG2080@2 NA|NA|NA C [2Fe-2S] binding domain MAG.T2.42_00025 1192034.CAP_6381 9.4e-122 444.5 Myxococcales 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUEA@1224,2WIYV@28221,2YXQ7@29,42MER@68525,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MAG.T2.42_00026 1267533.KB906733_gene3131 2.1e-60 239.6 Acidobacteriia 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 Bacteria 2JI4K@204432,3Y3NU@57723,COG1319@1,COG1319@2 NA|NA|NA C Molybdopterin dehydrogenase MAG.T2.42_00028 314230.DSM3645_20252 5e-54 218.4 Planctomycetes xdhC ko:K07402 ko00000 Bacteria 2IXRN@203682,COG1975@1,COG1975@2 NA|NA|NA O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family MAG.T2.42_00029 877414.ATWA01000007_gene169 2.3e-08 66.2 Clostridia nboR 1.1.1.328,2.7.7.76 ko:K07141,ko:K19190 ko00760,ko00790,ko01120,map00760,map00790,map01120 R10131,R10132,R11582 RC03053 ko00000,ko00001,ko01000 Bacteria 1UY6E@1239,249PV@186801,COG2068@1,COG2068@2 NA|NA|NA G HD domain MAG.T2.42_00031 1469245.JFBG01000034_gene1426 3.6e-51 208.8 Chromatiales 2.1.1.72 ko:K00571,ko:K07316 ko00000,ko01000,ko02048 Bacteria 1MX9M@1224,1T62C@1236,1X1WS@135613,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase MAG.T2.42_00032 869210.Marky_1688 3.1e-103 382.1 Deinococcus-Thermus purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 1WITC@1297,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) MAG.T2.42_00033 1211114.ALIP01000044_gene2021 1.5e-57 229.2 Xanthomonadales purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1RCWJ@1224,1S3VN@1236,1X58Z@135614,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T2.42_00034 713587.THITH_09765 1.3e-14 89.0 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG3055@1,COG3055@2,COG5640@1,COG5640@2 NA|NA|NA G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.42_00035 1123257.AUFV01000015_gene3552 3.6e-131 475.7 Xanthomonadales pykF4 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1NNNX@1224,1RYF5@1236,1X9M9@135614,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase, barrel domain MAG.T2.42_00036 383372.Rcas_0336 5.5e-25 122.9 Chloroflexia Bacteria 2GACY@200795,375GK@32061,COG0515@1,COG0515@2 NA|NA|NA KLT SMART tyrosine protein kinase MAG.T2.42_00037 313628.LNTAR_17423 2.7e-15 87.4 Bacteria cspA ko:K03704 ko00000,ko03000 Bacteria COG1278@1,COG1278@2 NA|NA|NA K Cold shock MAG.T2.42_00038 404589.Anae109_4248 2.5e-21 107.5 Proteobacteria Bacteria 1NADT@1224,2E3AG@1,32Y9Z@2 NA|NA|NA MAG.T2.42_00039 45157.CMB151CT 1.6e-56 226.1 Eukaryota MET14 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0055114,GO:0071704,GO:1901564 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iMM904.YKL001C,iND750.YKL001C Eukaryota COG0529@1,KOG0635@2759 NA|NA|NA F adenylylsulfate kinase activity MAG.T2.42_00040 335283.Neut_1189 6.3e-119 434.5 Nitrosomonadales cysN GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUD9@1224,2VHYV@28216,371VC@32003,COG2895@1,COG2895@2 NA|NA|NA H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily MAG.T2.42_00041 1124780.ANNU01000028_gene952 1.5e-113 416.0 Cytophagia cysD GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 47JCC@768503,4NEPD@976,COG0175@1,COG0175@2 NA|NA|NA EH TIGRFAM sulfate adenylyltransferase, small subunit MAG.T2.42_00042 522306.CAP2UW1_0778 5.9e-104 384.4 Betaproteobacteria cysA GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 3.6.3.25,3.6.3.29 ko:K02017,ko:K02045,ko:K10112 ko00920,ko02010,map00920,map02010 M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.6.1,3.A.1.6.3,3.A.1.8 Bacteria 1QTTT@1224,2VH92@28216,COG1118@1,COG1118@2 NA|NA|NA P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system MAG.T2.42_00043 717785.HYPMC_0719 1.3e-93 349.7 Hyphomicrobiaceae cysW ko:K02047 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 Bacteria 1MV8X@1224,2TQR8@28211,3N668@45401,COG4208@1,COG4208@2 NA|NA|NA P Sulfate ABC transporter inner membrane subunit CysW MAG.T2.42_00044 269796.Rru_A3401 1.1e-91 343.2 Rhodospirillales cysT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02018,ko:K02046 ko00920,ko02010,map00920,map02010 M00185,M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3,3.A.1.8 iJN746.PP_5170 Bacteria 1QTTU@1224,2JPE0@204441,2TTET@28211,COG0555@1,COG0555@2 NA|NA|NA O sulfate transport system, permease MAG.T2.42_00045 1120973.AQXL01000115_gene650 3.9e-118 431.4 Bacilli sbp ko:K02048 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 Bacteria 1TS25@1239,4HD5R@91061,COG1613@1,COG1613@2 NA|NA|NA P COG1613 ABC-type sulfate transport system, periplasmic component MAG.T2.42_00046 867903.ThesuDRAFT_00610 2.6e-125 455.7 Clostridiales incertae sedis hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 1TPNH@1239,248II@186801,3WCHX@538999,COG0001@1,COG0001@2 NA|NA|NA H Aminotransferase class-III MAG.T2.42_00047 1121438.JNJA01000009_gene4116 1.9e-88 332.8 Desulfovibrionales hemB GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 iECABU_c1320.ECABU_c04500,iEcSMS35_1347.EcSMS35_0398,iJN746.PP_2913,ic_1306.c0477 Bacteria 1MWMW@1224,2M85A@213115,2WJE8@28221,42N17@68525,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family MAG.T2.42_00048 264732.Moth_1248 3.3e-84 319.3 Thermoanaerobacterales cobA GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.2.1.75 ko:K01719,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS15755 Bacteria 1TQNH@1239,2487I@186801,42ES8@68295,COG0007@1,COG0007@2,COG1587@1,COG1587@2 NA|NA|NA H Belongs to the precorrin methyltransferase family MAG.T2.42_00049 1120934.KB894425_gene1204 6.8e-40 172.9 Pseudonocardiales hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0510 Bacteria 2GMWI@201174,4DYAU@85010,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps MAG.T2.42_00050 926550.CLDAP_18800 9.3e-152 543.9 Chloroflexi cysI GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0020037,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0097159,GO:1901363 1.7.7.1,1.8.1.2,1.8.7.1 ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_3037,iECH74115_1262.ECH74115_4017,iECIAI1_1343.ECIAI1_2867,iECNA114_1301.ECNA114_2794,iECO103_1326.ECO103_3307,iECSE_1348.ECSE_3019,iECSF_1327.ECSF_2552,iECSP_1301.ECSP_3712,iECUMN_1333.ECUMN_3091,iECW_1372.ECW_m2971,iECs_1301.ECs3618,iEKO11_1354.EKO11_1005,iEcE24377_1341.EcE24377A_3065,iSFV_1184.SFV_2742,iSbBS512_1146.SbBS512_E3112,iWFL_1372.ECW_m2971,iZ_1308.Z4073 Bacteria 2G7ZA@200795,COG0155@1,COG0155@2 NA|NA|NA C Nitrite and sulphite reductase 4Fe-4S domain MAG.T2.42_00051 562970.Btus_0193 3.7e-55 221.9 Alicyclobacillaceae cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 ko:K00390,ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R02021,R04928 RC00002,RC00007,RC00078,RC02862 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSMI@1239,277XK@186823,4HA9E@91061,COG0175@1,COG0175@2 NA|NA|NA EH Belongs to the PAPS reductase family. CysH subfamily MAG.T2.42_00052 1210884.HG799464_gene10872 2.6e-59 236.1 Bacteria ko:K07159 ko00000 Bacteria COG2047@1,COG2047@2 NA|NA|NA S protein (ATP-grasp superfamily) MAG.T2.42_00053 1198114.AciX9_3708 1.2e-08 66.2 Bacteria Bacteria COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 MAG.T2.42_00054 1126627.BAWE01000004_gene1801 2.3e-13 81.6 Bradyrhizobiaceae ko:K07075 ko00000 Bacteria 1N81V@1224,2UGQ6@28211,3K4GB@41294,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T2.42_00055 1142394.PSMK_22160 1.8e-215 755.4 Planctomycetes guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2IX19@203682,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP MAG.T2.42_00057 335543.Sfum_2452 4.7e-17 94.7 Proteobacteria 2.7.11.1 ko:K04757 ko00000,ko01000,ko01001,ko03021 Bacteria 1N9EJ@1224,COG2172@1,COG2172@2 NA|NA|NA T Histidine kinase-like ATPase domain MAG.T2.42_00058 1244869.H261_16957 4.1e-16 90.9 Alphaproteobacteria 2.4.1.187 ko:K04749,ko:K05946,ko:K06378 ko05111,map05111 ko00000,ko00001,ko01000,ko01003,ko03021 GT26 Bacteria 1N6U1@1224,2UFPK@28211,COG1366@1,COG1366@2 NA|NA|NA T Belongs to the anti-sigma-factor antagonist family MAG.T2.42_00059 1142394.PSMK_21940 1.2e-48 200.3 Planctomycetes ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IX01@203682,COG0767@1,COG0767@2 NA|NA|NA Q Belongs to the MlaE permease family MAG.T2.42_00060 1142394.PSMK_14850 1.1e-134 486.9 Planctomycetes mqnC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX1I@203682,COG1060@1,COG1060@2 NA|NA|NA H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.42_00062 661478.OP10G_0899 1.8e-26 127.5 Bacteria 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria COG1470@1,COG1470@2 NA|NA|NA S cell adhesion involved in biofilm formation MAG.T2.42_00064 351627.Csac_0835 5.1e-82 311.2 Thermoanaerobacterales ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPY2@1239,25CC3@186801,42F8X@68295,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family MAG.T2.42_00065 469383.Cwoe_2865 1.7e-69 270.8 Rubrobacteria ko:K07071 ko00000 Bacteria 2GJS0@201174,4CQ48@84995,COG1090@1,COG1090@2 NA|NA|NA S Domain of unknown function (DUF1731) MAG.T2.42_00066 1142394.PSMK_10290 1.9e-103 383.3 Planctomycetes rpoN ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 2IXGU@203682,COG1508@1,COG1508@2 NA|NA|NA K rna polymerase sigma-54 factor MAG.T2.42_00067 1142394.PSMK_28440 4.9e-123 448.0 Planctomycetes nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXB1@203682,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate MAG.T2.42_00069 530564.Psta_4579 4.6e-53 215.7 Planctomycetes Bacteria 2IXDR@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.42_00070 292564.Cyagr_1476 1.3e-91 344.7 Cyanobium prcA 3.4.11.10,3.4.24.25 ko:K05994,ko:K08604 ko05110,ko05111,map05110,map05111 ko00000,ko00001,ko01000,ko01002 Bacteria 1G04W@1117,22TFY@167375,COG1404@1,COG1404@2,COG4935@1,COG4935@2 NA|NA|NA E Belongs to the peptidase S8 family MAG.T2.42_00074 1123242.JH636435_gene1310 3.3e-62 245.7 Planctomycetes argK 5.4.99.2 ko:K01849,ko:K07588 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 2J2GB@203682,COG1703@1,COG1703@2,COG2185@1,COG2185@2 NA|NA|NA E ArgK protein MAG.T2.42_00075 1297742.A176_04257 4.1e-17 95.9 Proteobacteria Bacteria 1R9DA@1224,2EH3D@1,33AVD@2 NA|NA|NA S Protein of unknown function (DUF3592) MAG.T2.42_00076 1304885.AUEY01000061_gene2832 1.6e-22 114.4 Desulfobacterales Bacteria 1MZHI@1224,2MN6K@213118,2WUM4@28221,43BRC@68525,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats MAG.T2.42_00077 1142394.PSMK_27970 5e-26 124.4 Planctomycetes dinB Bacteria 2IZUW@203682,COG2318@1,COG2318@2 NA|NA|NA S DinB family MAG.T2.42_00078 1210884.HG799467_gene13387 1.4e-98 366.3 Planctomycetes tdcB 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYNJ@203682,COG1171@1,COG1171@2 NA|NA|NA E Threonine dehydratase MAG.T2.42_00079 497964.CfE428DRAFT_2280 2.3e-59 236.5 Verrucomicrobia Bacteria 46SS8@74201,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T2.42_00081 1210884.HG799462_gene8899 4.3e-55 222.6 Planctomycetes Bacteria 2J2KX@203682,COG2382@1,COG2382@2 NA|NA|NA P Putative esterase MAG.T2.42_00082 1333507.AUTQ01000094_gene505 2e-11 75.9 Pseudoalteromonadaceae ybaY ko:K03668,ko:K09914 ko00000 Bacteria 1N9XV@1224,1S4T0@1236,2Q2E3@267888,COG3126@1,COG3126@2,COG3187@1,COG3187@2 NA|NA|NA O Type III secretion system lipoprotein chaperone (YscW) MAG.T2.42_00083 1283300.ATXB01000002_gene2888 5.2e-31 141.7 Bacteria Bacteria 2DP87@1,330Z8@2 NA|NA|NA MAG.T2.42_00084 394221.Mmar10_1145 5.8e-55 220.7 Hyphomonadaceae Bacteria 1REJ6@1224,29KMP@1,2UAW7@28211,307IZ@2,43XXB@69657 NA|NA|NA S Domain of unknown function (DUF4287) MAG.T2.42_00085 575540.Isop_0388 3.4e-41 176.0 Planctomycetes hpaIM 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 2IWRP@203682,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family MAG.T2.42_00086 1379270.AUXF01000002_gene1182 2.2e-63 248.8 Gemmatimonadetes upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1ZT1C@142182,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate MAG.T2.42_00087 246197.MXAN_1432 2.2e-94 352.4 Myxococcales ltaA 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 1MWCR@1224,2WIQP@28221,2YUBW@29,42MZS@68525,COG2008@1,COG2008@2 NA|NA|NA E Threonine aldolase MAG.T2.42_00088 1210884.HG799462_gene9224 3.1e-54 219.9 Planctomycetes Bacteria 2BZKQ@1,2J2ZU@203682,32S71@2 NA|NA|NA MAG.T2.42_00089 314230.DSM3645_11247 3.2e-18 99.0 Planctomycetes Bacteria 2ERTX@1,2J34S@203682,33JD4@2 NA|NA|NA MAG.T2.42_00091 1142394.PSMK_03630 3.1e-78 298.9 Planctomycetes neuC GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576 3.2.1.184,5.1.3.14 ko:K01791,ko:K18429 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R10187 RC00005,RC00288,RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2J0I1@203682,COG0381@1,COG0381@2 NA|NA|NA M UDP-N-acetylglucosamine 2-epimerase MAG.T2.42_00093 1142394.PSMK_12550 5.9e-62 244.6 Planctomycetes ko:K03496 ko00000,ko03036,ko04812 Bacteria 2IX5Z@203682,COG1192@1,COG1192@2 NA|NA|NA D involved in chromosome partitioning MAG.T2.42_00094 886293.Sinac_5925 3.5e-102 379.0 Planctomycetes rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 2IWTE@203682,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 MAG.T2.42_00095 521674.Plim_2876 7.4e-32 144.4 Planctomycetes ko:K02282 ko00000,ko02035,ko02044 Bacteria 2J0EY@203682,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T2.42_00096 460265.Mnod_6162 5.6e-48 199.1 Alphaproteobacteria 2.7.13.3 ko:K07708 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1NC9X@1224,2TXEG@28211,COG0784@1,COG0784@2,COG3852@1,COG3852@2 NA|NA|NA T histidine kinase A domain protein MAG.T2.42_00098 326427.Cagg_3085 5.3e-31 141.4 Chloroflexia nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2G6MY@200795,375PN@32061,COG1057@1,COG1057@2 NA|NA|NA F Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) MAG.T2.42_00099 1150469.RSPPHO_00430 2.3e-09 69.7 Rhodospirillales MA20_16045 1.17.7.4,3.2.2.9 ko:K01243,ko:K03527 ko00270,ko00900,ko01100,ko01110,ko01130,ko01230,map00270,map00900,map01100,map01110,map01130,map01230 M00034,M00096,M00609 R00194,R01401,R05884,R08210 RC00063,RC00318,RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 Bacteria 1PETT@1224,2JU46@204441,2TTTB@28211,COG0775@1,COG0775@2 NA|NA|NA F Phosphorylase superfamily MAG.T2.42_00102 383372.Rcas_2885 1.1e-33 149.8 Bacteria ycfB Bacteria COG1598@1,COG1598@2 NA|NA|NA N PFAM Uncharacterised protein family UPF0150 MAG.T2.42_00103 118161.KB235922_gene1511 2.1e-17 94.4 Pleurocapsales ko:K07339 ko00000,ko01000,ko02048 Bacteria 1G91K@1117,3VKRB@52604,COG1724@1,COG1724@2 NA|NA|NA N HicA toxin of bacterial toxin-antitoxin, MAG.T2.42_00104 443598.AUFA01000013_gene6694 2.6e-46 193.4 Proteobacteria 2.3.1.43 ko:K00650 ko00564,ko04979,map00564,map04979 R02114 RC00037,RC00055 ko00000,ko00001,ko01000 Bacteria 1R0B6@1224,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T2.42_00105 1458357.BG58_31745 1.5e-70 274.6 Proteobacteria Bacteria 1RD7A@1224,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like MAG.T2.42_00106 94624.Bpet0419 2.3e-83 316.2 Alcaligenaceae ampG ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria 1QTSE@1224,2WGIZ@28216,3T20Z@506,COG2211@1,COG2211@2 NA|NA|NA G Major facilitator superfamily MAG.T2.42_00107 391625.PPSIR1_34707 8.3e-86 324.3 Proteobacteria Bacteria 1R5KK@1224,COG0491@1,COG0491@2 NA|NA|NA S COG0491 Zn-dependent hydrolases, including glyoxylases MAG.T2.42_00108 1142394.PSMK_05650 9.1e-21 106.3 Planctomycetes rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0XA@203682,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 MAG.T2.42_00109 1396141.BATP01000020_gene105 1.8e-251 876.3 Verrucomicrobiae hyuA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016885,GO:0017144,GO:0018710,GO:0042180,GO:0043443,GO:0044237,GO:0044281,GO:0071704,GO:1901568,GO:1902224 3.5.2.14,3.5.2.9,6.4.1.6,6.4.1.8 ko:K01469,ko:K01473,ko:K01474,ko:K10701,ko:K10855 ko00330,ko00480,ko00642,ko01100,ko01120,ko01220,map00330,map00480,map00642,map01100,map01120,map01220 R00251,R03187,R05453 RC00040,RC00553,RC00632 ko00000,ko00001,ko01000 iNJ661.Rv0266c Bacteria 2IU32@203494,46UMR@74201,COG0145@1,COG0145@2,COG0146@1,COG0146@2 NA|NA|NA EQ Hydantoinase B/oxoprolinase MAG.T2.42_00110 15368.BRADI3G45977.1 5e-09 67.4 Poales CNX7 GO:0006464,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009719,GO:0009725,GO:0009733,GO:0009734,GO:0009755,GO:0009987,GO:0010033,GO:0018315,GO:0019538,GO:0023052,GO:0032870,GO:0036211,GO:0042040,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071365,GO:0071495,GO:0071704,GO:1901564 2.8.1.12 ko:K03635,ko:K21232 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Viridiplantae 37WD6@33090,3GKBW@35493,3IJ47@38820,3M0W9@4447,KOG3474@1,KOG3474@2759 NA|NA|NA C Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin MAG.T2.42_00111 395019.Bmul_5398 3.6e-47 196.1 Burkholderiaceae moeA GO:0001941,GO:0003674,GO:0003824,GO:0005102,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006605,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0007399,GO:0007416,GO:0008092,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009898,GO:0009987,GO:0015031,GO:0015631,GO:0015833,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0019897,GO:0019898,GO:0022607,GO:0030425,GO:0030674,GO:0031234,GO:0032324,GO:0032501,GO:0032502,GO:0032947,GO:0033036,GO:0034613,GO:0034641,GO:0036211,GO:0036477,GO:0042040,GO:0042278,GO:0042802,GO:0042803,GO:0042886,GO:0042995,GO:0043005,GO:0043113,GO:0043170,GO:0043226,GO:0043412,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045202,GO:0045211,GO:0046039,GO:0046128,GO:0046483,GO:0046907,GO:0046983,GO:0048731,GO:0048856,GO:0050808,GO:0051179,GO:0051186,GO:0051188,GO:0051189,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0051649,GO:0051668,GO:0055086,GO:0060077,GO:0060090,GO:0061024,GO:0061598,GO:0061599,GO:0065003,GO:0070566,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072521,GO:0072578,GO:0072579,GO:0072657,GO:0090407,GO:0097060,GO:0097112,GO:0097447,GO:0097458,GO:0098552,GO:0098562,GO:0098590,GO:0098794,GO:0099173,GO:0099572,GO:0120025,GO:0120038,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 1K5C9@119060,1MVD5@1224,2VIFK@28216,COG0303@1,COG0303@2 NA|NA|NA H Molybdenum cofactor synthesis domain MAG.T2.42_00113 886293.Sinac_6222 2.1e-10 73.2 Planctomycetes ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2J4VP@203682,COG2165@1,COG2165@2 NA|NA|NA NU Protein of unknown function (DUF1559) MAG.T2.42_00114 933262.AXAM01000156_gene1041 1.2e-17 97.4 Deltaproteobacteria Bacteria 1NUIA@1224,2DV5M@1,2WV1Z@28221,33U68@2,42ZFX@68525 NA|NA|NA MAG.T2.42_00115 886293.Sinac_0176 1.9e-30 141.4 Planctomycetes ko:K02282 ko00000,ko02035,ko02044 Bacteria 2IZ04@203682,COG1413@1,COG1413@2,COG2199@1,COG3706@2 NA|NA|NA C GGDEF domain MAG.T2.42_00116 483219.LILAB_00570 7.4e-30 137.5 Myxococcales rimJ2 Bacteria 1RKT9@1224,2WS7R@28221,2Z14V@29,42VCK@68525,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T2.42_00117 485913.Krac_11762 8.5e-117 427.2 Chloroflexi tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN746.PP_0436,iLJ478.TM0478 Bacteria 2G64J@200795,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) MAG.T2.42_00119 94624.Bpet1873 2.4e-22 112.5 Betaproteobacteria 2.3.1.189 ko:K03824,ko:K15520 ko00000,ko01000 Bacteria 1QTXW@1224,2WGH8@28216,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) domain MAG.T2.42_00121 1210884.HG799462_gene8340 1.2e-206 726.5 Planctomycetes speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iIT341.HP0422,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Bacteria 2IX6P@203682,COG1166@1,COG1166@2 NA|NA|NA H Catalyzes the biosynthesis of agmatine from arginine MAG.T2.42_00122 671143.DAMO_2743 2.2e-46 191.8 unclassified Bacteria ko:K07064 ko00000 Bacteria 2NRZ1@2323,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T2.42_00124 1056820.KB900699_gene1312 4.8e-135 488.4 Alteromonadales genera incertae sedis 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1MVDD@1224,1T1Z4@1236,2PP37@256005,COG3391@1,COG3391@2,COG4222@1,COG4222@2 NA|NA|NA S Esterase-like activity of phytase MAG.T2.42_00125 1379270.AUXF01000001_gene1941 1.6e-79 304.3 Gemmatimonadetes Bacteria 1ZUHA@142182,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Tetratricopeptide repeat MAG.T2.42_00126 713587.THITH_15855 3.1e-73 282.3 Chromatiales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0421 Bacteria 1MUPV@1224,1RNXV@1236,1WW7U@135613,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) MAG.T2.42_00127 82654.Pse7367_2190 3.8e-27 129.8 Oscillatoriales Bacteria 1G09B@1117,1H82F@1150,COG0642@1,COG0784@1,COG0784@2,COG2202@1,COG2202@2,COG2205@2,COG3829@1,COG3829@2,COG5002@1,COG5002@2 NA|NA|NA T PhoQ Sensor MAG.T2.42_00128 1142394.PSMK_04960 1.2e-36 160.2 Planctomycetes coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 Bacteria 2IZJA@203682,COG0452@1,COG0452@2 NA|NA|NA H COG0452 Phosphopantothenoylcysteine synthetase decarboxylase MAG.T2.42_00129 1142394.PSMK_15860 1.2e-170 606.7 Planctomycetes gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXSA@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.42_00130 1142394.PSMK_15850 1.5e-144 519.2 Planctomycetes pilT ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IXRP@203682,COG2805@1,COG2805@2 NA|NA|NA NU COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT MAG.T2.42_00132 1142394.PSMK_20220 7e-200 703.7 Planctomycetes gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXGK@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.42_00133 1142394.PSMK_20230 1.3e-131 476.5 Planctomycetes pilC ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX2A@203682,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretory pathway component PulF MAG.T2.42_00141 502025.Hoch_6539 5.2e-44 187.2 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_00142 502025.Hoch_6539 1.5e-38 168.3 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_00143 1123508.JH636442_gene4137 4e-67 261.5 Planctomycetes uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2IX6Z@203682,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T2.42_00144 1142394.PSMK_01010 1.4e-126 459.9 Planctomycetes purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Bacteria 2IWZH@203682,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP MAG.T2.42_00145 1142394.PSMK_13450 5.5e-84 318.2 Planctomycetes hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2IWR5@203682,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound MAG.T2.42_00146 278957.ABEA03000041_gene2214 2.8e-32 145.2 Opitutae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 3K80H@414999,46VZR@74201,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein MAG.T2.42_00147 237368.SCABRO_01906 3.5e-12 78.2 Bacteria rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA MAG.T2.42_00148 1142394.PSMK_26360 1e-52 213.4 Planctomycetes pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2IZXT@203682,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis MAG.T2.42_00149 1142394.PSMK_26350 3.9e-26 125.2 Planctomycetes ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2J050@203682,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance MAG.T2.42_00150 1142394.PSMK_26340 4.8e-113 414.5 Planctomycetes prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 2IXI0@203682,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) MAG.T2.42_00151 1142394.PSMK_26330 2.7e-53 215.7 Planctomycetes glmU GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 Bacteria 2IXXB@203682,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain MAG.T2.42_00153 648996.Theam_0592 1.7e-09 68.6 Aquificae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2G49M@200783,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA MAG.T2.42_00154 1142394.PSMK_28330 1.9e-27 129.8 Planctomycetes ko:K07052 ko00000 Bacteria 2J06D@203682,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T2.42_00155 1123368.AUIS01000012_gene771 5.7e-61 241.1 Acidithiobacillales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4715 Bacteria 1MWK5@1224,1RM8I@1236,2NC4T@225057,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) MAG.T2.42_00157 1142394.PSMK_05130 9.2e-60 237.3 Planctomycetes yicC ko:K03316 ko00000 2.A.36 Bacteria 2IYZH@203682,COG1561@1,COG1561@2 NA|NA|NA S stress-induced protein MAG.T2.42_00158 682795.AciX8_2530 2.2e-176 625.5 Acidobacteriia glpD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2JI40@204432,3Y2YF@57723,COG0578@1,COG0578@2 NA|NA|NA C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family MAG.T2.42_00159 575540.Isop_2476 3.9e-175 621.3 Planctomycetes glpK GO:0003674,GO:0003824,GO:0004370,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0033554,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901575,GO:1901615,GO:1901616 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 iE2348C_1286.E2348C_4230,iECNA114_1301.ECNA114_4065,iECSF_1327.ECSF_3786 Bacteria 2IXQW@203682,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate MAG.T2.42_00160 1123023.JIAI01000001_gene6247 7.4e-159 568.2 Pseudonocardiales Bacteria 2GJSV@201174,4DXMY@85010,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase MAG.T2.42_00162 756272.Plabr_0465 1.3e-25 122.9 Planctomycetes accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 2IZJ6@203682,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA MAG.T2.42_00163 1142394.PSMK_21030 1.3e-158 566.2 Planctomycetes accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWZV@203682,COG0439@1,COG0439@2 NA|NA|NA I Biotin carboxylase MAG.T2.42_00165 368408.Tpen_1168 2.5e-07 63.5 Crenarchaeota Archaea 2XSH6@28889,COG1305@1,arCOG02165@2157 NA|NA|NA E Transglutaminase/protease-like homologues MAG.T2.42_00166 1142394.PSMK_01460 1.8e-68 266.2 Planctomycetes mlaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IX01@203682,COG0767@1,COG0767@2 NA|NA|NA Q Belongs to the MlaE permease family MAG.T2.42_00168 1282356.H045_21190 1.8e-07 61.2 Pseudomonas fluorescens group trkA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 ko:K03499,ko:K05571 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.63.1,2.A.63.2 iE2348C_1286.E2348C_3552 Bacteria 1MW8R@1224,1RNVQ@1236,1YP0A@136843,COG0569@1,COG0569@2 NA|NA|NA P potassium uptake MAG.T2.42_00169 1304885.AUEY01000096_gene2839 4.5e-87 329.3 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity MAG.T2.42_00170 545264.KB898745_gene1357 1.1e-37 164.9 Chromatiales Bacteria 1MVUV@1224,1RNIV@1236,1WZXR@135613,COG1943@1,COG1943@2 NA|NA|NA L COG1943 Transposase and inactivated derivatives MAG.T2.42_00172 309801.trd_A0739 7.6e-11 75.5 Thermomicrobia tlpA Bacteria 27YHJ@189775,2G72F@200795,COG0526@1,COG0526@2 NA|NA|NA CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T2.42_00173 886293.Sinac_4642 1.4e-22 114.4 Bacteria Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis MAG.T2.42_00174 1396141.BATP01000040_gene2152 3.6e-111 408.3 Verrucomicrobiae ko:K03924 ko00000,ko01000 Bacteria 2ITT6@203494,46S9V@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) MAG.T2.42_00175 575540.Isop_3568 1.3e-58 233.4 Planctomycetes Bacteria 2IXT7@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.42_00176 1396141.BATP01000040_gene2150 6.9e-16 91.7 Bacteria Bacteria 2BXEQ@1,33IN8@2 NA|NA|NA MAG.T2.42_00177 1396141.BATP01000040_gene2149 9.2e-63 247.3 Bacteria mxaC ko:K07114,ko:K16257 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria COG2304@1,COG2304@2 NA|NA|NA IU oxidoreductase activity MAG.T2.42_00178 575540.Isop_3571 7.8e-55 221.1 Bacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria COG2304@1,COG2304@2 NA|NA|NA IU oxidoreductase activity MAG.T2.42_00179 575540.Isop_3572 3.4e-09 69.3 Bacteria Bacteria 2ECWJ@1,336TU@2 NA|NA|NA MAG.T2.42_00180 1396141.BATP01000040_gene2146 1.3e-84 322.0 Bacteria Bacteria 2DUKG@1,33R4D@2 NA|NA|NA MAG.T2.42_00181 595494.Tola_1754 3.9e-64 251.9 Aeromonadales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1MW7S@1224,1RPGK@1236,1Y61V@135624,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T2.42_00182 331678.Cphamn1_2212 5.1e-88 331.6 Chlorobi Bacteria 1FEIM@1090,COG3174@1,COG3174@2 NA|NA|NA S Domain of unknown function (DUF4010) MAG.T2.42_00183 1454004.AW11_01555 2.3e-48 199.5 Betaproteobacteria Bacteria 1NMET@1224,2W6HS@28216,COG2931@1,COG2931@2 NA|NA|NA Q PEP-CTERM motif MAG.T2.42_00184 28444.JODQ01000014_gene6918 9.5e-43 181.4 Streptosporangiales ko:K03933 ko00000 AA10,CBM73 Bacteria 2GP7X@201174,4EJ0K@85012,COG3397@1,COG3397@2,COG3979@1,COG3979@2 NA|NA|NA S Lytic polysaccharide mono-oxygenase, cellulose-degrading MAG.T2.42_00185 1121957.ATVL01000011_gene3792 7.3e-115 420.6 Cytophagia namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 47JFR@768503,4NF98@976,COG1902@1,COG1902@2 NA|NA|NA C NADH flavin oxidoreductase NADH oxidase MAG.T2.42_00186 1379698.RBG1_1C00001G0247 6.5e-33 148.7 Bacteria Bacteria COG2208@1,COG2208@2 NA|NA|NA T phosphoserine phosphatase activity MAG.T2.42_00187 1230342.CTM_15148 4.4e-60 238.8 Clostridiaceae Bacteria 1UYV5@1239,24B0A@186801,36DRS@31979,COG0793@1,COG0793@2 NA|NA|NA M Peptidase, S41 MAG.T2.42_00188 243365.CV_4365 1.1e-27 130.6 Neisseriales ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1MV1C@1224,2KR9I@206351,2VKRW@28216,COG2095@1,COG2095@2 NA|NA|NA U MarC family integral membrane protein MAG.T2.42_00191 1142394.PSMK_16820 3e-174 619.0 Planctomycetes pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2IWTI@203682,COG0210@1,COG0210@2 NA|NA|NA L COG0210 Superfamily I DNA and RNA MAG.T2.42_00192 42256.RradSPS_1319 3e-35 154.8 Actinobacteria vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 2GU71@201174,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T2.42_00193 42256.RradSPS_1320 1.2e-12 79.0 Bacteria ko:K18829 ko00000,ko02048 Bacteria COG4456@1,COG4456@2 NA|NA|NA MAG.T2.42_00194 479434.Sthe_2440 4.2e-167 595.1 Chloroflexi 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 2GBNH@200795,COG1505@1,COG1505@2 NA|NA|NA E Peptidase S9, prolyl oligopeptidase active site domain protein MAG.T2.42_00195 1219581.HMPREF1628_02570 1.5e-30 141.0 Actinobacteria pknL 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2GJ1J@201174,4D3IX@85005,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.42_00196 65071.PYU1_T002902 5.7e-116 424.5 Pythiales SER33 GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0061759,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Eukaryota 1MES7@121069,COG0111@1,KOG0068@2759 NA|NA|NA E D-3-phosphoglycerate dehydrogenase. Source PGD MAG.T2.42_00198 926550.CLDAP_03880 8.8e-41 174.1 Chloroflexi map 1.17.1.1,3.4.11.18 ko:K00523,ko:K01265 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000,ko01002 Bacteria 2G6AV@200795,COG0024@1,COG0024@2 NA|NA|NA J TIGRFAM methionine aminopeptidase, type I MAG.T2.42_00199 926550.CLDAP_27470 2.6e-84 319.3 Chloroflexi hutI 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 iYO844.BSU39370 Bacteria 2G5KM@200795,COG1228@1,COG1228@2 NA|NA|NA Q PFAM amidohydrolase MAG.T2.42_00200 266117.Rxyl_2932 9.7e-22 110.2 Bacteria sixA ko:K08296 ko00000,ko01000 Bacteria COG2062@1,COG2062@2 NA|NA|NA T phosphohistidine phosphatase, SixA MAG.T2.42_00201 1142394.PSMK_16100 7.6e-123 448.7 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IXKI@203682,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.42_00203 1142394.PSMK_15110 4.6e-47 195.7 Bacteria Bacteria COG0308@1,COG0308@2 NA|NA|NA E peptide catabolic process MAG.T2.42_00206 1869.MB27_14350 1e-12 82.4 Micromonosporales 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2IBPU@201174,4DAU6@85008,COG0515@1,COG0515@2,COG2199@1,COG2203@1,COG2203@2,COG3706@2,COG3899@1,COG3899@2 NA|NA|NA T Domain present in phytochromes and cGMP-specific phosphodiesterases. MAG.T2.42_00207 768679.TTX_1496 7.1e-78 297.4 Crenarchaeota prpB 4.1.3.30 ko:K03417 ko00640,map00640 R00409 RC00286,RC00287 ko00000,ko00001,ko01000 Archaea 2XPMR@28889,COG2513@1,arCOG00581@2157 NA|NA|NA G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate MAG.T2.42_00208 1142394.PSMK_02940 0.0 1368.6 Planctomycetes nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IX3H@203682,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen MAG.T2.42_00209 1142394.PSMK_02910 2.5e-77 295.4 Planctomycetes dcd GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZ2N@203682,COG0717@1,COG0717@2 NA|NA|NA F dUTPase MAG.T2.42_00211 880073.Calab_3167 2.1e-82 314.3 Bacteria Bacteria COG1629@1,COG4771@2 NA|NA|NA P transport MAG.T2.42_00213 1122176.KB903587_gene4522 2.8e-52 213.4 Sphingobacteriia yebA ko:K08642 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Bacteria 1J0XQ@117747,4PKU5@976,COG0739@1,COG0739@2,COG3291@1,COG3291@2 NA|NA|NA M heme binding MAG.T2.42_00214 998088.B565_2532 4.4e-102 378.6 Gammaproteobacteria 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1QTZP@1224,1RPB9@1236,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T2.42_00215 1121920.AUAU01000018_gene1791 2.8e-147 528.9 Acidobacteria Bacteria 3Y3D1@57723,COG0457@1,COG0457@2 NA|NA|NA O Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T2.42_00217 502025.Hoch_6846 1.3e-31 142.5 Myxococcales pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2667 Bacteria 1MU60@1224,2WJET@28221,2YV42@29,42MGN@68525,COG0077@1,COG0077@2,COG1605@1,COG1605@2 NA|NA|NA E Prephenate dehydratase MAG.T2.42_00218 886293.Sinac_5043 2.9e-132 479.6 Planctomycetes dsbD 1.8.1.8 ko:K04084,ko:K06888 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 2IX0N@203682,COG1331@1,COG1331@2,COG4233@1,COG4233@2 NA|NA|NA O COG1331 Highly conserved protein containing a thioredoxin domain MAG.T2.42_00219 502025.Hoch_1845 1.4e-94 354.0 Myxococcales dtpT ko:K03305 ko00000 2.A.17 Bacteria 1MW6W@1224,2WKK6@28221,2YTWP@29,42NNY@68525,COG3104@1,COG3104@2 NA|NA|NA E POT family MAG.T2.42_00220 575540.Isop_1372 1.3e-173 616.7 Planctomycetes Bacteria 2IXPD@203682,COG3591@1,COG3591@2 NA|NA|NA E Peptidase S46 MAG.T2.42_00222 1142394.PSMK_14030 9.2e-69 268.9 Planctomycetes ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IX4B@203682,COG1450@1,COG1450@2 NA|NA|NA NU general secretion pathway protein D MAG.T2.42_00226 521674.Plim_3639 2.6e-18 100.5 Planctomycetes gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 ko:K02460,ko:K12286 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IXHV@203682,COG3156@1,COG3156@2 NA|NA|NA U Type II secretion system (T2SS), protein K MAG.T2.42_00230 338969.Rfer_0534 1.2e-16 93.2 Comamonadaceae lspG ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1QW3U@1224,2WHHY@28216,4AJXB@80864,COG4968@1,COG4968@2 NA|NA|NA U Type II secretion system (T2SS), protein G MAG.T2.42_00231 1142394.PSMK_16780 8.1e-57 228.0 Planctomycetes gspF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXYZ@203682,COG1459@1,COG1459@2 NA|NA|NA U Type 4 fimbrial assembly protein pilC MAG.T2.42_00232 1142394.PSMK_23890 4.5e-127 461.8 Planctomycetes xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXGK@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.42_00235 114615.BRADO1241 2e-35 156.4 Alphaproteobacteria Bacteria 1P5T7@1224,2DTVQ@1,2UW2C@28211,33MVA@2 NA|NA|NA MAG.T2.42_00237 864051.BurJ1DRAFT_0325 1.1e-147 530.4 Bacteria ko:K08162,ko:K08226,ko:K16211 ko00000,ko02000 2.A.1.2.21,2.A.1.41,2.A.2.6 Bacteria COG2270@1,COG2270@2 NA|NA|NA G Major facilitator Superfamily MAG.T2.42_00238 497964.CfE428DRAFT_6514 1.5e-74 287.0 Bacteria ko:K07098 ko00000 Bacteria COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T2.42_00239 402881.Plav_1325 2.9e-18 99.4 Rhodobiaceae ko:K06219 ko00000 Bacteria 1JQH2@119043,1NACD@1224,2VCHE@28211,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T2.42_00241 1408418.JNJH01000066_gene1745 8.4e-58 231.1 Proteobacteria 3.1.3.3 ko:K07315,ko:K16922 ko00000,ko01000,ko01002,ko03021 Bacteria 1RAA4@1224,COG1716@1,COG1716@2,COG2208@1,COG2208@2 NA|NA|NA T FHA Domain MAG.T2.42_00242 1121456.ATVA01000019_gene1265 2.4e-07 62.0 Deltaproteobacteria ko:K04749 ko00000,ko03021 Bacteria 1NECY@1224,2WWSD@28221,431WN@68525,COG1366@1,COG1366@2 NA|NA|NA T STAS domain MAG.T2.42_00243 999541.bgla_1g20800 3.1e-13 82.4 Burkholderiaceae Bacteria 1K4XG@119060,1R5V0@1224,2VRY4@28216,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) MAG.T2.42_00244 414684.RC1_0280 2.9e-46 193.0 Rhodospirillales ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MUFW@1224,2JQ7V@204441,2U2CU@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_00245 861299.J421_0677 0.0 1194.5 Bacteria acrB ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 Bacteria COG0841@1,COG0841@2 NA|NA|NA V transmembrane transporter activity MAG.T2.42_00246 96561.Dole_1704 1.6e-19 104.4 Desulfobacterales Bacteria 1MZHI@1224,2MN6K@213118,2WUM4@28221,43BRC@68525,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats MAG.T2.42_00247 1120950.KB892746_gene3462 4e-23 116.7 Propionibacteriales Bacteria 2I9D0@201174,4DSNJ@85009,COG4447@1,COG4447@2 NA|NA|NA S cellulose binding MAG.T2.42_00248 746697.Aeqsu_1982 1.4e-07 64.3 Bacteria Bacteria COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_00249 1142394.PSMK_20940 3.2e-36 158.3 Planctomycetes Bacteria 2IZAH@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.42_00250 37919.EP51_00405 5.5e-67 263.1 Nocardiaceae Bacteria 2GIZ1@201174,4FUTU@85025,COG0515@1,COG0515@2,COG3903@1,COG3903@2 NA|NA|NA K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation MAG.T2.42_00254 1142394.PSMK_11020 9.6e-128 463.8 Planctomycetes serS GO:0000049,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005524,GO:0008144,GO:0016597,GO:0017076,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0046983,GO:0070905,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IXGP@203682,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) MAG.T2.42_00256 1280954.HPO_15923 7.8e-29 133.7 Bacteria Bacteria 2EH3D@1,33AVD@2 NA|NA|NA S Protein of unknown function (DUF3592) MAG.T2.42_00257 1142394.PSMK_14460 1.1e-52 213.8 Planctomycetes nadK 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2IXD3@203682,COG0061@1,COG0061@2 NA|NA|NA H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP MAG.T2.42_00258 523850.TON_0789 1.2e-39 169.9 Thermococci pflX 1.97.1.4 ko:K04070 ko00000,ko01000 Archaea 242QN@183968,2XUM6@28890,COG1313@1,arCOG00934@2157 NA|NA|NA O 4Fe-4S single cluster domain MAG.T2.42_00260 278957.ABEA03000130_gene1701 2.4e-165 589.0 Bacteria ycf46 3.6.4.6 ko:K06027 ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962 ko00000,ko00001,ko01000,ko04131 1.F.1.1 Bacteria COG0464@1,COG0464@2 NA|NA|NA O ATPase activity MAG.T2.42_00265 278957.ABEA03000130_gene1696 6.4e-100 370.9 Opitutae ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 3K79X@414999,46S5Q@74201,COG2805@1,COG2805@2 NA|NA|NA NU twitching motility protein MAG.T2.42_00266 1340493.JNIF01000003_gene2645 5.2e-52 212.6 Acidobacteria ko:K06880 ko00000,ko01000,ko01504 Bacteria 3Y8PV@57723,COG2312@1,COG2312@2 NA|NA|NA S Erythromycin esterase MAG.T2.42_00267 1089550.ATTH01000001_gene1987 1.1e-49 204.9 Bacteroidetes Bacteria 4NKIR@976,COG2866@1,COG2866@2,COG2931@1,COG2931@2,COG3291@1,COG3291@2 NA|NA|NA Q SMART Integrin alpha beta-propellor repeat protein MAG.T2.42_00269 1142394.PSMK_27780 3.2e-15 88.6 Planctomycetes Bacteria 2E71C@1,2J130@203682,331K1@2 NA|NA|NA MAG.T2.42_00270 661478.OP10G_2392 8.6e-154 550.4 Bacteria 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase MAG.T2.42_00271 1463900.JOIX01000001_gene6449 3.2e-12 80.9 Actinobacteria Bacteria 2I9D0@201174,COG4447@1,COG4447@2 NA|NA|NA K cellulose binding MAG.T2.42_00272 448385.sce4890 1.1e-27 130.6 Proteobacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1N3BR@1224,COG1595@1,COG1595@2 NA|NA|NA K rna polymerase sigma factor MAG.T2.42_00273 1396141.BATP01000060_gene4647 2.5e-126 460.3 Verrucomicrobiae Bacteria 2IV44@203494,46UAE@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00274 926566.Terro_1486 2.2e-93 349.4 Acidobacteriia metB 4.4.1.1,4.4.1.8 ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R01001,R01286,R02408,R04770,R04930,R04941,R09366 RC00056,RC00069,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JM7U@204432,3Y6NC@57723,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T2.42_00275 1267533.KB906738_gene2239 3.2e-123 449.9 Acidobacteriia 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JHVD@204432,3Y2K5@57723,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T2.42_00276 1121920.AUAU01000008_gene1591 4.1e-21 108.2 Acidobacteria Bacteria 3Y8ZE@57723,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T2.42_00278 861299.J421_2390 1.6e-71 276.6 Gemmatimonadetes Bacteria 1ZT6R@142182,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T2.42_00280 83219.PM02_04515 5.8e-58 231.9 Sulfitobacter Bacteria 1N90Y@1224,2VE2N@28211,3ZYAZ@60136,COG4782@1,COG4782@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF900) MAG.T2.42_00281 1454004.AW11_00930 1.7e-65 256.1 unclassified Betaproteobacteria Bacteria 1KR2C@119066,1R8VC@1224,2C3WA@1,2WC2P@28216,2Z8P1@2 NA|NA|NA MAG.T2.42_00282 243090.RB8777 9.6e-89 334.0 Planctomycetes rho ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2IXBX@203682,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T2.42_00283 1121033.AUCF01000001_gene2076 2.3e-49 203.0 Rhodospirillales psuG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 4.2.1.70 ko:K16329 ko00240,map00240 R01055 RC00432,RC00433 ko00000,ko00001,ko01000 Bacteria 1MUQU@1224,2JR4R@204441,2TUKT@28211,COG2313@1,COG2313@2 NA|NA|NA Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway MAG.T2.42_00284 717605.Theco_1426 7.6e-94 351.3 Paenibacillaceae cshA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,26RXA@186822,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity MAG.T2.42_00285 1142394.PSMK_09540 6.6e-59 235.0 Planctomycetes alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 2IZJH@203682,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids MAG.T2.42_00288 1162668.LFE_1432 8.2e-38 164.5 Bacteria GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 MAG.T2.42_00290 861299.J421_6341 9.5e-19 99.8 Gemmatimonadetes Bacteria 1ZTY8@142182,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain MAG.T2.42_00291 1144275.COCOR_03031 1.8e-09 70.1 Proteobacteria ko:K07052 ko00000 Bacteria 1NID0@1224,COG1266@1,COG1266@2 NA|NA|NA S metal-dependent membrane protease MAG.T2.42_00292 595460.RRSWK_07188 5.2e-09 70.1 Bacteria 3.4.24.3 ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity MAG.T2.42_00295 391625.PPSIR1_15030 4.6e-21 109.8 Bacteria ko:K20543 ko00000,ko02000 1.B.55.3 Bacteria COG3118@1,COG3118@2 NA|NA|NA O belongs to the thioredoxin family MAG.T2.42_00296 290397.Adeh_0265 6.8e-13 81.3 Myxococcales 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1MUBN@1224,2WKX9@28221,2YUX4@29,42MBA@68525,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T2.42_00297 429009.Adeg_1835 8e-43 181.4 Thermoanaerobacterales kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016769,GO:0016874,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0070280,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.37,2.3.1.47,2.3.1.50,6.2.1.14 ko:K00639,ko:K00643,ko:K00652,ko:K00654,ko:K01906,ko:K10915,ko:K21784 ko00260,ko00333,ko00600,ko00780,ko00860,ko01100,ko01110,ko01130,ko02024,ko04071,ko04138,ko05111,map00260,map00333,map00600,map00780,map00860,map01100,map01110,map01130,map02024,map04071,map04138,map05111 M00094,M00099,M00123,M00573,M00577,M00837,M00838 R00371,R00830,R01281,R03209,R03210,R10124,R11667 RC00004,RC00014,RC00039,RC00394,RC02725,RC02815,RC02849 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 1TPUX@1239,2491D@186801,42FUG@68295,COG0156@1,COG0156@2 NA|NA|NA H PFAM Aminotransferase class I and II MAG.T2.42_00298 1142394.PSMK_07920 6.9e-38 164.9 Planctomycetes ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2IZ7X@203682,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol MAG.T2.42_00299 1267533.KB906733_gene3472 1.4e-91 344.7 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00300 1210884.HG799465_gene11805 9.6e-58 231.1 Bacteria Bacteria 2DBWE@1,2ZBGD@2 NA|NA|NA MAG.T2.42_00301 1210884.HG799465_gene11806 6.8e-146 525.0 Bacteria Bacteria COG1752@1,COG1752@2 NA|NA|NA M Esterase of the alpha-beta hydrolase superfamily MAG.T2.42_00302 66874.JOFS01000035_gene569 2e-150 539.7 Actinobacteria 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2H23J@201174,COG2303@1,COG2303@2 NA|NA|NA E GMC oxidoreductase MAG.T2.42_00303 1218075.BAYA01000044_gene6617 2.2e-135 490.3 Burkholderiaceae Bacteria 1K52M@119060,1R58S@1224,2VJWF@28216,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T2.42_00304 1121104.AQXH01000002_gene601 2e-71 276.2 Bacteria petH GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464 1.14.13.208,1.18.1.2,1.19.1.1 ko:K00528,ko:K02287,ko:K02641,ko:K15511 ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100 R09555,R10159 RC01739 ko00000,ko00001,ko00194,ko01000 iJN678.petH Bacteria COG0369@1,COG0369@2 NA|NA|NA C hydroxylamine reductase activity MAG.T2.42_00305 1382359.JIAL01000001_gene270 2.5e-103 382.5 Bacteria ko:K07133 ko00000 Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily MAG.T2.42_00306 1142394.PSMK_28350 4.9e-137 494.6 Planctomycetes murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2IWRI@203682,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine MAG.T2.42_00307 69395.JQLZ01000002_gene1332 1.4e-44 186.8 Caulobacterales spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1QQ53@1224,2KGC5@204458,2TVH5@28211,COG0566@1,COG0566@2 NA|NA|NA J PFAM tRNA rRNA methyltransferase (SpoU) MAG.T2.42_00308 1049564.TevJSym_cc00010 2.7e-40 173.3 Gammaproteobacteria Bacteria 1R5PK@1224,1RP0G@1236,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T2.42_00309 1142394.PSMK_16770 3.4e-10 73.2 Planctomycetes ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2J1FA@203682,COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents periplasmic component MAG.T2.42_00310 335543.Sfum_2449 6.6e-74 284.3 Syntrophobacterales mlaF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MUSD@1224,2MQE7@213462,2WKRT@28221,42NI4@68525,COG1127@1,COG1127@2 NA|NA|NA Q PFAM ABC transporter MAG.T2.42_00313 649638.Trad_0907 2.9e-135 488.8 Bacteria CP_1013 2.7.7.23,2.7.7.83 ko:K00972,ko:K11442 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00361,M00362 R00416 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria COG4284@1,COG4284@2 NA|NA|NA G Utp--glucose-1-phosphate uridylyltransferase MAG.T2.42_00314 62928.azo1645 4.3e-90 337.8 Rhodocyclales pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 iAF1260.b2564,iAF987.Gmet_1885,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 Bacteria 1MU9W@1224,2KV09@206389,2VHY7@28216,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate MAG.T2.42_00315 521674.Plim_1486 1.6e-27 129.8 Planctomycetes phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 ko:K02039 ko00000 Bacteria 2IYX4@203682,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake MAG.T2.42_00316 1142394.PSMK_07280 2.4e-82 312.4 Planctomycetes dapA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0032787,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.72,4.3.3.7 ko:K01714,ko:K03517 ko00261,ko00300,ko00760,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00760,map01100,map01110,map01120,map01130,map01230 M00016,M00115,M00525,M00526,M00527 R04292,R10147 RC01119,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812 Bacteria 2IXII@203682,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) MAG.T2.42_00317 1142394.PSMK_31960 2.9e-37 161.8 Planctomycetes 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2J1PQ@203682,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T2.42_00318 479434.Sthe_1657 1.2e-69 270.8 Thermomicrobia nfo GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 27XEG@189775,2G5XZ@200795,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin MAG.T2.42_00320 1142394.PSMK_11720 5.4e-38 163.7 Planctomycetes queF 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 R07605 RC01875 ko00000,ko00001,ko01000,ko03016 Bacteria 2J07W@203682,COG0780@1,COG0780@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) MAG.T2.42_00321 290397.Adeh_4264 6e-77 294.7 Myxococcales ybbD 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVAJ@1224,2WK5Q@28221,2Z31B@29,42N8K@68525,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain MAG.T2.42_00322 1142394.PSMK_15140 1.7e-176 626.3 Planctomycetes ubiD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_4669,iIT341.HP0396 Bacteria 2IYCA@203682,COG0043@1,COG0043@2 NA|NA|NA H COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and MAG.T2.42_00323 1156937.MFUM_170030 5.5e-83 314.7 unclassified Verrucomicrobia msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 37G70@326457,46TM8@74201,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T2.42_00324 1396141.BATP01000062_gene4444 2.9e-45 189.5 Verrucomicrobiae 3.2.1.35 ko:K22144 ko00000,ko00536,ko01000 Bacteria 2IVF7@203494,46WEI@74201,COG1262@1,COG1262@2,COG3794@1,COG3794@2 NA|NA|NA N Sulfatase-modifying factor enzyme 1 MAG.T2.42_00325 945713.IALB_2904 1.8e-53 217.2 Bacteria 3.4.19.5 ko:K13051 ko00000,ko01000,ko01002 Bacteria COG4242@1,COG4242@2 NA|NA|NA PQ Belongs to the peptidase S51 family MAG.T2.42_00327 926549.KI421517_gene665 2e-51 209.1 Cytophagia Bacteria 47PYG@768503,4NNH0@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T2.42_00329 1005048.CFU_1786 8.3e-41 174.1 Betaproteobacteria ko:K15256 ko00000,ko01000,ko03016 Bacteria 1R23X@1224,2WI94@28216,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain MAG.T2.42_00330 661478.OP10G_2213 2.2e-239 835.9 Bacteria Bacteria COG1621@1,COG1621@2,COG4354@1,COG4354@2 NA|NA|NA G intracellular protein transport MAG.T2.42_00331 862908.BMS_3067 3.5e-108 399.1 Deltaproteobacteria yqiK ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria 1QIR4@1224,2WJDJ@28221,42Q0N@68525,COG2268@1,COG2268@2 NA|NA|NA S Band 7 protein MAG.T2.42_00332 338963.Pcar_0143 3.9e-12 78.6 Deltaproteobacteria Bacteria 1N8YP@1224,29X52@1,2WT2G@28221,30IU1@2,42WWU@68525 NA|NA|NA MAG.T2.42_00335 1144275.COCOR_02615 1.1e-62 246.9 Deltaproteobacteria yxaA ko:K07090 ko00000 Bacteria 1NJ47@1224,2WN5M@28221,42QRS@68525,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein MAG.T2.42_00336 246197.MXAN_4781 6.4e-20 104.0 Bacteria ywjH Bacteria COG4272@1,COG4272@2 NA|NA|NA S membrane MAG.T2.42_00337 1267211.KI669560_gene2835 5.5e-137 494.6 Bacteroidetes 1.1.1.41,1.1.1.42 ko:K00030,ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R00709,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 4NGUA@976,COG0473@1,COG0473@2 NA|NA|NA CE Isocitrate isopropylmalate dehydrogenase MAG.T2.42_00338 1185876.BN8_05038 8.4e-40 170.2 Cytophagia Bacteria 2AYX9@1,31R2Z@2,47RDY@768503,4NNS4@976 NA|NA|NA S DinB superfamily MAG.T2.42_00339 622637.KE124774_gene1454 3e-235 821.2 Alphaproteobacteria Bacteria 1MUJH@1224,2TSB8@28211,COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase A MAG.T2.42_00340 1142394.PSMK_20720 9e-107 393.7 Planctomycetes pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_1415,iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176 Bacteria 2IXSW@203682,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily MAG.T2.42_00341 1142394.PSMK_23740 8.3e-36 157.1 Planctomycetes rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZD3@203682,COG0203@1,COG0203@2 NA|NA|NA J ribosomal protein l17 MAG.T2.42_00342 1142394.PSMK_23760 5.2e-105 387.9 Planctomycetes rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXPQ@203682,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.42_00343 1142394.PSMK_23770 2.3e-44 184.9 Planctomycetes rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZCP@203682,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome MAG.T2.42_00344 1142394.PSMK_23780 5.6e-38 163.7 Planctomycetes rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZK8@203682,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MAG.T2.42_00345 481448.Minf_1443 6.9e-08 62.0 Bacteria rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family MAG.T2.42_00346 1121406.JAEX01000007_gene2431 2.7e-21 107.5 Desulfovibrionales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1MZFU@1224,2MCF7@213115,2WPZK@28221,42TRU@68525,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T2.42_00347 290397.Adeh_1924 3.4e-51 208.8 Myxococcales map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1MU99@1224,2WJMN@28221,2YU2D@29,42MM5@68525,COG0024@1,COG0024@2 NA|NA|NA J TIGRFAM methionine aminopeptidase, type I MAG.T2.42_00348 1142394.PSMK_28990 9e-142 510.4 Planctomycetes secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2IXN6@203682,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently MAG.T2.42_00349 382464.ABSI01000011_gene2652 2.2e-29 135.6 Verrucomicrobiae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUE6@203494,46SSX@74201,COG0200@1,COG0200@2 NA|NA|NA J Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MAG.T2.42_00350 1142394.PSMK_29010 1.9e-47 196.1 Planctomycetes rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ7J@203682,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body MAG.T2.42_00351 289376.THEYE_A1430 7.8e-29 133.3 Nitrospirae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 3J0QF@40117,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance MAG.T2.42_00352 886293.Sinac_0470 5.3e-45 187.6 Planctomycetes rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ8X@203682,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center MAG.T2.42_00353 1142394.PSMK_29040 7.4e-33 146.7 Planctomycetes rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ8I@203682,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit MAG.T2.42_00354 373903.Hore_01300 3.3e-12 77.0 Halanaerobiales rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,24QR1@186801,3WAWA@53433,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site MAG.T2.42_00355 1121104.AQXH01000010_gene2435 3.9e-42 178.3 Sphingobacteriia rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IPX4@117747,4NEGY@976,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits MAG.T2.42_00356 1142394.PSMK_29070 2.7e-26 124.8 Bacteria rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit MAG.T2.42_00357 1142394.PSMK_29080 3.4e-43 181.0 Planctomycetes rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZMA@203682,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome MAG.T2.42_00358 575540.Isop_2088 2.3e-16 91.7 Planctomycetes rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0WD@203682,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA MAG.T2.42_00360 1142394.PSMK_29110 1.5e-47 195.7 Planctomycetes rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZPH@203682,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs MAG.T2.42_00361 1142394.PSMK_29120 1.5e-84 319.3 Planctomycetes rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IWWU@203682,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation MAG.T2.42_00362 1121403.AUCV01000025_gene2251 4.9e-22 110.5 Desulfobacterales rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RH0W@1224,2MKFE@213118,2WQBH@28221,42TRE@68525,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome MAG.T2.42_00363 314230.DSM3645_09382 8.1e-29 132.9 Planctomycetes rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0BB@203682,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA MAG.T2.42_00364 1142394.PSMK_29150 1.6e-93 349.4 Planctomycetes rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IXD9@203682,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity MAG.T2.42_00365 1142394.PSMK_29160 5.2e-17 93.6 Planctomycetes rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0VE@203682,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome MAG.T2.42_00366 1142394.PSMK_29170 4.2e-49 201.4 Planctomycetes rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IYU2@203682,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel MAG.T2.42_00367 1142394.PSMK_29180 1.2e-62 246.5 Planctomycetes rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IY9T@203682,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit MAG.T2.42_00368 1142394.PSMK_29190 1.3e-40 172.2 Planctomycetes rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZQR@203682,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes MAG.T2.42_00372 1142394.PSMK_20520 1.3e-68 266.5 Planctomycetes Bacteria 2J55H@203682,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 MAG.T2.42_00373 1298608.JCM18900_128 1e-13 82.8 Moraxellaceae ydzA Bacteria 1N9NR@1224,1SGYH@1236,3NP07@468,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.42_00374 314230.DSM3645_12451 6.3e-10 72.4 Planctomycetes Bacteria 2C7TA@1,2IXIJ@203682,2Z9TR@2 NA|NA|NA MAG.T2.42_00375 96561.Dole_1787 1.7e-16 95.1 Desulfobacterales 3.2.1.81 ko:K01219,ko:K03749,ko:K15725 ko00000,ko01000,ko02000 1.B.17.2.2 Bacteria 1N4S6@1224,2MNRP@213118,2X729@28221,43BRE@68525,COG1653@1,COG1653@2,COG3210@1,COG3210@2,COG3266@1,COG3266@2,COG5492@1,COG5492@2 NA|NA|NA G domain protein MAG.T2.42_00376 1142394.PSMK_20170 9.2e-36 157.5 Bacteria ko:K09384 ko00000 Bacteria COG1075@1,COG1075@2 NA|NA|NA KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T2.42_00379 1142394.PSMK_09570 1.9e-72 279.6 Planctomycetes yhaM ko:K03698 ko00000,ko01000,ko03019 Bacteria 2IX5B@203682,COG3481@1,COG3481@2 NA|NA|NA S Nucleic acid binding MAG.T2.42_00380 76114.ebA5163 7.9e-27 128.3 Rhodocyclales ko:K04033 ko00000,ko03000 Bacteria 1Q3UX@1224,2KWHG@206389,2VT4I@28216,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator MAG.T2.42_00381 1142394.PSMK_13700 3.9e-52 212.2 Planctomycetes nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2IYWH@203682,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T2.42_00382 247490.KSU1_C0508 1.2e-76 294.3 Planctomycetes omcB Bacteria 2IY9X@203682,COG1361@1,COG1361@2 NA|NA|NA M 60 kDa outer membrane protein MAG.T2.42_00383 479434.Sthe_2590 2.6e-55 223.4 Bacteria Bacteria COG0420@1,COG0420@2 NA|NA|NA L 3'-5' exonuclease activity MAG.T2.42_00386 521674.Plim_2411 6.5e-24 117.9 Planctomycetes RB9536 Bacteria 2J0V4@203682,32Y28@2,COG1226@1 NA|NA|NA P Ion channel MAG.T2.42_00387 1403819.BATR01000131_gene4676 1.3e-57 232.3 Verrucomicrobiae 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IUKA@203494,46Z3P@74201,COG1082@1,COG1082@2,COG3386@1,COG3386@2 NA|NA|NA G Arylesterase MAG.T2.42_00388 452637.Oter_3509 9e-104 384.0 Opitutae Bacteria 3K8Y2@414999,46TMZ@74201,COG0673@1,COG0673@2 NA|NA|NA S PFAM oxidoreductase domain protein MAG.T2.42_00389 388051.AUFE01000004_gene926 1.1e-16 93.2 Betaproteobacteria Bacteria 1N7MV@1224,2VUFU@28216,32YV7@2,COG1226@1 NA|NA|NA P Ion channel MAG.T2.42_00390 1288484.APCS01000023_gene465 2.2e-98 365.5 Bacteria scoA 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria COG1788@1,COG1788@2 NA|NA|NA I CoA-transferase activity MAG.T2.42_00393 261292.Nit79A3_1327 6.1e-169 600.9 Nitrosomonadales Bacteria 1R9S5@1224,2W13M@28216,37499@32003,COG0402@1,COG0402@2 NA|NA|NA F Amidohydrolase family MAG.T2.42_00394 261292.Nit79A3_1326 2.5e-72 278.9 Nitrosomonadales smuG ko:K10800 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1R207@1224,2WBUV@28216,373UC@32003,COG1573@1,COG1573@2 NA|NA|NA L Uracil DNA glycosylase superfamily MAG.T2.42_00395 861299.J421_0129 2e-55 223.4 Bacteria Bacteria COG1835@1,COG1835@2 NA|NA|NA I transferase activity, transferring acyl groups other than amino-acyl groups MAG.T2.42_00396 661478.OP10G_2546 1.2e-63 250.8 Bacteria clcA ko:K03281 ko00000 2.A.49 Bacteria COG0038@1,COG0038@2 NA|NA|NA P chloride channel MAG.T2.42_00403 1142394.PSMK_19560 8.6e-126 458.0 Planctomycetes ko:K02662 ko00000,ko02035,ko02044 Bacteria 2IWXB@203682,COG4972@1,COG4972@2 NA|NA|NA NU TIGRFAM type IV pilus assembly protein PilM MAG.T2.42_00404 314230.DSM3645_19393 2.1e-76 293.1 Planctomycetes ispH 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 2IY6M@203682,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 MAG.T2.42_00406 765420.OSCT_0770 2.9e-15 90.5 Chloroflexia Bacteria 2GB82@200795,377IZ@32061,COG5295@1,COG5295@2 NA|NA|NA UW Hep Hag repeat protein MAG.T2.42_00407 1142394.PSMK_23040 4.8e-44 186.0 Planctomycetes Bacteria 2J0FW@203682,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T2.42_00409 268407.PWYN_01440 4.3e-74 286.6 Paenibacillaceae DSE4 3.2.1.73 ko:K01216 ko00000,ko01000 Bacteria 1U7U3@1239,26SHU@186822,4IT1H@91061,COG2273@1,COG2273@2,COG5498@1,COG5498@2 NA|NA|NA M glycoside hydrolase family 81 MAG.T2.42_00410 1254432.SCE1572_43615 7.8e-27 127.1 Bacteria vapC Bacteria COG5611@1,COG5611@2 NA|NA|NA S PIN domain MAG.T2.42_00412 243231.GSU0233 3.2e-36 158.7 Desulfuromonadales yceH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K03810,ko:K09915 ko00000 Bacteria 1RA13@1224,2WP10@28221,42S8C@68525,43TU3@69541,COG3132@1,COG3132@2 NA|NA|NA S Protein of unknown function, DUF480 MAG.T2.42_00416 1121033.AUCF01000005_gene5320 7.6e-157 560.5 Rhodospirillales Bacteria 1MW20@1224,2JPHY@204441,2TQY4@28211,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T2.42_00418 1128421.JAGA01000003_gene3523 1.6e-06 62.0 unclassified Bacteria MA20_41400 Bacteria 2NR5F@2323,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase MAG.T2.42_00419 1142394.PSMK_17790 4.9e-91 341.3 Planctomycetes ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IXFI@203682,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase MAG.T2.42_00420 1123072.AUDH01000006_gene3261 6.5e-155 553.5 Rhodospirillales lipA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1427,iB21_1397.B21_00586,iBWG_1329.BWG_0499,iE2348C_1286.E2348C_0528,iEC55989_1330.EC55989_0620,iECABU_c1320.ECABU_c06820,iECBD_1354.ECBD_3023,iECB_1328.ECB_00597,iECDH10B_1368.ECDH10B_0589,iECDH1ME8569_1439.ECDH1ME8569_0597,iECD_1391.ECD_00597,iECED1_1282.ECED1_0624,iECH74115_1262.ECH74115_0716,iECIAI1_1343.ECIAI1_0611,iECIAI39_1322.ECIAI39_0603,iECNA114_1301.ECNA114_0567,iECO103_1326.ECO103_0635,iECO111_1330.ECO111_0658,iECO26_1355.ECO26_0702,iECOK1_1307.ECOK1_0638,iECP_1309.ECP_0658,iECS88_1305.ECS88_0669,iECSE_1348.ECSE_0695,iECSF_1327.ECSF_0567,iECSP_1301.ECSP_0681,iECUMN_1333.ECUMN_0720,iECW_1372.ECW_m0682,iECs_1301.ECs0666,iEKO11_1354.EKO11_3238,iETEC_1333.ETEC_0656,iEcDH1_1363.EcDH1_2998,iEcE24377_1341.EcE24377A_0652,iEcHS_1320.EcHS_A0679,iEcSMS35_1347.EcSMS35_0648,iEcolC_1368.EcolC_3017,iG2583_1286.G2583_0791,iJO1366.b0628,iLF82_1304.LF82_1199,iNRG857_1313.NRG857_02855,iSBO_1134.SBO_0492,iSDY_1059.SDY_0550,iSF_1195.SF0653,iSFxv_1172.SFxv_0720,iSSON_1240.SSON_0582,iS_1188.S0675,iSbBS512_1146.SbBS512_E0542,iUMN146_1321.UM146_14375,iUMNK88_1353.UMNK88_663,iUTI89_1310.UTI89_C0631,iWFL_1372.ECW_m0682,iY75_1357.Y75_RS03275,ic_1306.c0718 Bacteria 1MVRD@1224,2JQJB@204441,2TRP3@28211,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives MAG.T2.42_00421 1396141.BATP01000060_gene4560 1.5e-68 268.1 Verrucomicrobiae Bacteria 2IV44@203494,46UAE@74201,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00422 530564.Psta_2472 2.3e-14 86.3 Planctomycetes cmk 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2J10J@203682,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T2.42_00423 1142394.PSMK_12320 1.1e-117 430.6 Planctomycetes radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2IYD6@203682,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function MAG.T2.42_00424 1142394.PSMK_27240 1.6e-42 180.6 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.42_00425 1142394.PSMK_27240 1.1e-31 144.8 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.42_00426 1142394.PSMK_07590 1.1e-240 840.1 Planctomycetes purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IXRT@203682,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T2.42_00427 502025.Hoch_6539 1.7e-38 167.9 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_00428 452637.Oter_1389 1.3e-112 414.8 Opitutae Bacteria 3K8AK@414999,46VB0@74201,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.42_00429 232721.Ajs_2106 2.5e-21 109.0 Comamonadaceae ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1MURJ@1224,2WA1J@28216,4AFHN@80864,COG1285@1,COG1285@2 NA|NA|NA S MgtC family MAG.T2.42_00430 1142394.PSMK_20130 4.3e-48 198.4 Planctomycetes purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IYT2@203682,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T2.42_00432 237368.SCABRO_01915 1.6e-55 223.4 Planctomycetes gnnA ko:K09949 ko00000 iAF987.Gmet_2352 Bacteria 2IXAX@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T2.42_00435 1120985.AUMI01000015_gene1463 1.4e-48 201.4 Negativicutes Bacteria 1TP3F@1239,4H2BH@909932,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.42_00436 886293.Sinac_5446 5.1e-15 87.8 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2IZAB@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_00437 861299.J421_1867 0.0 1190.6 Bacteria cobN 6.6.1.2 ko:K02230 ko00860,ko01100,map00860,map01100 R05227 RC02000 ko00000,ko00001,ko01000 Bacteria COG1429@1,COG1429@2 NA|NA|NA H ligase activity, forming nitrogen-metal bonds MAG.T2.42_00438 861299.J421_1880 5.5e-41 174.1 Bacteria Bacteria COG1672@1,COG1672@2 NA|NA|NA MAG.T2.42_00439 251221.35211725 1.9e-83 316.2 Cyanobacteria Bacteria 1G29P@1117,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T2.42_00440 861299.J421_1872 6.4e-184 650.6 Bacteria Bacteria COG2303@1,COG2303@2 NA|NA|NA E choline dehydrogenase activity MAG.T2.42_00441 118173.KB235914_gene1527 3.3e-51 208.8 Oscillatoriales glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 1G3MJ@1117,1H9H5@1150,COG0580@1,COG0580@2 NA|NA|NA G Major intrinsic protein MAG.T2.42_00442 215803.DB30_0441 3.7e-109 401.7 Myxococcales gcd Bacteria 1NXSN@1224,2X3QX@28221,2YWVR@29,438FZ@68525,COG1063@1,COG1063@2 NA|NA|NA E Glucose dehydrogenase C-terminus MAG.T2.42_00443 1382306.JNIM01000001_gene3277 1.7e-24 119.4 Chloroflexi ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 Bacteria 2G6J4@200795,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin MAG.T2.42_00444 1125863.JAFN01000001_gene27 9.5e-19 100.1 Deltaproteobacteria nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03625 ko00000,ko03009,ko03021 Bacteria 1N94P@1224,2WRNH@28221,42SEA@68525,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons MAG.T2.42_00445 1142394.PSMK_00390 7.6e-89 334.0 Planctomycetes ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2IXAG@203682,COG0552@1,COG0552@2 NA|NA|NA D Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) MAG.T2.42_00446 1142394.PSMK_16020 1.1e-09 70.5 Planctomycetes Bacteria 2IY7F@203682,COG4968@1,COG4968@2 NA|NA|NA NU Pfam:N_methyl_2 MAG.T2.42_00449 1167006.UWK_01624 1.3e-118 433.7 Desulfobacterales ko:K03688 ko00000 Bacteria 1MU1Z@1224,2MHU5@213118,2WK1B@28221,42N87@68525,COG0661@1,COG0661@2 NA|NA|NA S pfam abc-1 MAG.T2.42_00450 1123508.JH636442_gene3813 5.3e-12 79.0 Planctomycetes comF 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2J03E@203682,COG1040@1,COG1040@2 NA|NA|NA S Phosphoribosyl transferase domain MAG.T2.42_00452 1122185.N792_00885 2.3e-19 104.0 Gammaproteobacteria ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1NK7B@1224,1SIMC@1236,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.42_00454 886293.Sinac_6956 4.6e-201 708.4 Planctomycetes ko:K09992 ko00000 Bacteria 2IWYB@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type MAG.T2.42_00455 1242864.D187_005351 0.0 1181.8 Myxococcales Bacteria 1MX3A@1224,2X3XW@28221,2YXIE@29,438QJ@68525,COG0823@1,COG0823@2,COG1228@1,COG1228@2 NA|NA|NA QU WD40-like Beta Propeller Repeat MAG.T2.42_00456 661478.OP10G_1529 1.8e-155 556.2 Bacteria Bacteria COG4805@1,COG4805@2 NA|NA|NA S Bacterial protein of unknown function (DUF885) MAG.T2.42_00457 1242864.D187_007737 5.6e-121 441.8 Myxococcales Bacteria 1Q3C4@1224,2X49B@28221,2YYJ7@29,4393F@68525,COG1164@1,COG1164@2 NA|NA|NA E Oligoendopeptidase f MAG.T2.42_00458 109760.SPPG_00943T0 3.5e-81 308.5 Fungi Fungi 2A301@1,2RY45@2759,39WFB@33154,3P17R@4751 NA|NA|NA MAG.T2.42_00459 344747.PM8797T_14319 1.2e-78 300.4 Planctomycetes gspF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IXYZ@203682,COG1459@1,COG1459@2 NA|NA|NA U Type 4 fimbrial assembly protein pilC MAG.T2.42_00460 287.DR97_528 2.9e-52 213.4 Pseudomonas aeruginosa group Bacteria 1N0IJ@1224,1S05Z@1236,1YICG@136841,COG5316@1,COG5316@2 NA|NA|NA S Domain of unknown function (DUF4139) MAG.T2.42_00461 205922.Pfl01_1973 5.9e-17 94.4 Pseudomonas fluorescens group gspG2 ko:K02246,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1RDX2@1224,1S69B@1236,1YURS@136843,COG2165@1,COG2165@2 NA|NA|NA U General secretion pathway MAG.T2.42_00465 314230.DSM3645_27348 4e-06 60.1 Planctomycetes ko:K02662 ko00000,ko02035,ko02044 Bacteria 2IZK7@203682,COG4972@1,COG4972@2 NA|NA|NA NU PFAM Fimbrial assembly family protein MAG.T2.42_00467 1121129.KB903359_gene1233 3.8e-89 335.9 Porphyromonadaceae GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11,2.4.1.18 ko:K16149,ko:K16150 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R00292,R02110 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GH57,GT4 Bacteria 2325F@171551,2G0CZ@200643,4PKP8@976,COG0297@1,COG0297@2 NA|NA|NA G Starch synthase catalytic domain MAG.T2.42_00469 1142394.PSMK_05400 8.4e-63 247.3 Planctomycetes prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2IYX6@203682,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif MAG.T2.42_00470 402881.Plav_1269 3.7e-46 191.4 Rhodobiaceae 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1JPC0@119043,1RDHN@1224,2U98I@28211,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain MAG.T2.42_00474 1267005.KB911259_gene3953 2.1e-32 145.6 Bacteria 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria COG2203@1,COG2203@2 NA|NA|NA T Gaf domain MAG.T2.42_00475 1183438.GKIL_2537 3.2e-52 213.0 Cyanobacteria Bacteria 1G1UY@1117,COG0457@1,COG0457@2 NA|NA|NA S Alternative locus ID MAG.T2.42_00476 706587.Desti_0562 1.4e-87 330.5 Syntrophobacterales htrA GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2MQU0@213462,2WIWE@28221,42NB6@68525,COG0265@1,COG0265@2 NA|NA|NA M PDZ domain (Also known as DHR or GLGF) MAG.T2.42_00477 391625.PPSIR1_09565 9.2e-42 176.8 Myxococcales Bacteria 1RHRU@1224,2WPB8@28221,2YV8N@29,42SRT@68525,COG2947@1,COG2947@2 NA|NA|NA S EVE domain MAG.T2.42_00478 1379270.AUXF01000002_gene1278 2.7e-22 111.3 Gemmatimonadetes ko:K07075 ko00000 Bacteria 1ZUYI@142182,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T2.42_00479 263358.VAB18032_17975 9.4e-125 454.5 Micromonosporales Bacteria 2IDGN@201174,4D9RP@85008,COG4995@1,COG4995@2 NA|NA|NA S CHAT domain MAG.T2.42_00482 521674.Plim_3967 4.1e-15 87.4 Planctomycetes 2.1.1.72 ko:K03427,ko:K07726 ko00000,ko01000,ko02048,ko03000 Bacteria 2J1EG@203682,COG2944@1,COG2944@2 NA|NA|NA K sequence-specific DNA binding MAG.T2.42_00483 861299.J421_3996 3.7e-24 118.2 Gemmatimonadetes cyaA GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1ZTYF@142182,COG2954@1,COG2954@2,COG5607@1,COG5607@2 NA|NA|NA S CYTH MAG.T2.42_00484 1142394.PSMK_07410 3.1e-45 189.5 Planctomycetes holB 2.7.7.7 ko:K02341,ko:K02343,ko:K09384 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IZ3J@203682,COG0470@1,COG0470@2 NA|NA|NA L COG2812 DNA polymerase III, gamma tau subunits MAG.T2.42_00488 292459.STH181 1.8e-11 77.0 Clostridia rpoE ko:K03088 ko00000,ko03021 Bacteria 1VBIF@1239,24P38@186801,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.42_00490 450851.PHZ_c1261 8.8e-11 75.1 Caulobacterales degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0051716,GO:0051788,GO:0061077,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2KG2P@204458,2TS6B@28211,COG0265@1,COG0265@2 NA|NA|NA M Belongs to the peptidase S1C family MAG.T2.42_00492 1142394.PSMK_04970 1.9e-82 313.2 Planctomycetes ko:K07263 ko00000,ko01000,ko01002 Bacteria 2IY7Q@203682,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 MAG.T2.42_00493 1500890.JQNL01000001_gene388 5.3e-48 198.0 Xanthomonadales dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215,ko:K03546 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0510,iLJ478.TM1520,iSbBS512_1146.SbBS512_E0035 Bacteria 1MUCT@1224,1RMCZ@1236,1X4Q0@135614,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate MAG.T2.42_00495 1283299.AUKG01000001_gene1991 1.5e-24 118.6 Rubrobacteria 1.18.1.2,1.19.1.1 ko:K00528,ko:K05524 R10159 ko00000,ko01000 Bacteria 2IKVN@201174,4CQEK@84995,COG1146@1,COG1146@2 NA|NA|NA C PFAM 4Fe-4S ferredoxin, iron-sulfur binding MAG.T2.42_00499 1142394.PSMK_18400 8.6e-11 72.8 Planctomycetes rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J05Y@203682,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit MAG.T2.42_00502 1122182.KB903825_gene245 1.4e-29 136.7 Micromonosporales ko:K07010 ko00000,ko01002 Bacteria 2GIV6@201174,4DD3J@85008,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 MAG.T2.42_00503 1142394.PSMK_12520 1.8e-45 190.3 Bacteria gcvT 1.5.99.5,2.1.2.10 ko:K00605,ko:K06980,ko:K22086 ko00260,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200 M00532 R00609,R01221,R02300,R04125 RC00022,RC00069,RC00183,RC00190,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T2.42_00505 314256.OG2516_14935 4.5e-76 291.6 Oceanicola mvaB GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUMX@1224,2PCTM@252301,2TT1R@28211,COG0119@1,COG0119@2 NA|NA|NA E HMGL-like MAG.T2.42_00506 1142394.PSMK_08290 1.9e-38 166.4 Bacteria yeaP GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 ko:K13069 R08057 ko00000,ko01000 Bacteria COG2199@1,COG2199@2 NA|NA|NA T diguanylate cyclase activity MAG.T2.42_00507 1142394.PSMK_07970 3.7e-64 252.3 Planctomycetes murG GO:0008150,GO:0040007 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2J057@203682,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) MAG.T2.42_00508 1142394.PSMK_07960 3.3e-76 292.4 Planctomycetes ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2IZT9@203682,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T2.42_00509 1142394.PSMK_18470 9.6e-162 577.0 Planctomycetes miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2IX1E@203682,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine MAG.T2.42_00512 1122179.KB890415_gene1999 2e-14 88.2 Sphingobacteriia 3.4.24.3 ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria 1IXQ8@117747,4NYN2@976,COG3291@1,COG3291@2,COG4412@1,COG4412@2 NA|NA|NA G Reprolysin (M12B) family zinc metalloprotease MAG.T2.42_00514 575540.Isop_3017 5.4e-35 155.6 Planctomycetes ko:K02005 ko00000 Bacteria 2IZ3N@203682,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_00515 292459.STH976 5.9e-79 300.8 Clostridia macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,248EZ@186801,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T2.42_00516 575540.Isop_3019 1.1e-74 287.3 Planctomycetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IY2P@203682,COG0577@1,COG0577@2 NA|NA|NA V membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides MAG.T2.42_00517 1236959.BAMT01000001_gene1729 2.8e-92 346.3 Nitrosomonadales tolC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1NEHN@1224,2KKVJ@206350,2VYWE@28216,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.42_00518 1142394.PSMK_24940 2.6e-136 492.3 Planctomycetes gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 2IXGA@203682,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 MAG.T2.42_00519 1541065.JRFE01000058_gene5539 8.5e-27 127.5 Pleurocapsales Bacteria 1G2EG@1117,3VHV3@52604,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase required for the conversion of 2- phytyl-1,4-beta-naphthoquinol to phylloquinol MAG.T2.42_00520 1123508.JH636441_gene3712 7.2e-12 77.4 Planctomycetes hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 ko:K04082,ko:K05801 ko00000,ko03029,ko03110 Bacteria 2J3FJ@203682,COG1076@1,COG1076@2 NA|NA|NA O HSCB C-terminal oligomerisation domain MAG.T2.42_00521 118166.JH976537_gene3160 2e-165 589.3 Oscillatoriales sdcS_1 Bacteria 1G0FA@1117,1H7KC@1150,COG0471@1,COG0471@2 NA|NA|NA P Di- and tricarboxylate transporters MAG.T2.42_00522 1142394.PSMK_27240 1.3e-36 161.0 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.42_00523 1123070.KB899251_gene657 8.1e-153 547.0 Verrucomicrobiae ko:K00185 ko00000 5.A.3 Bacteria 2ITS8@203494,46U15@74201,COG5557@1,COG5557@2 NA|NA|NA C Polysulphide reductase, NrfD MAG.T2.42_00524 583355.Caka_0067 8.9e-123 446.8 Opitutae ko:K00184 ko00000 5.A.3 Bacteria 3K7GM@414999,46S66@74201,COG0437@1,COG0437@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T2.42_00525 1403819.BATR01000094_gene3013 6.2e-37 160.6 Verrucomicrobiae Bacteria 2IUG7@203494,46VBT@74201,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T2.42_00526 1403819.BATR01000094_gene3015 0.0 1166.4 Verrucomicrobiae napA GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0008940,GO:0009061,GO:0009325,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016661,GO:0030151,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:1902494 ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_2447,iECABU_c1320.ECABU_c25400,iECO103_1326.ECO103_2681,iECSE_1348.ECSE_2474,iECSF_1327.ECSF_2087,iECUMN_1333.ECUMN_2541,iEcHS_1320.EcHS_A2344,iEcolC_1368.EcolC_1444,iPC815.YPO3038,iSSON_1240.SSON_2264,ic_1306.c2745 Bacteria 2ITSW@203494,46UHE@74201,COG0243@1,COG0243@2 NA|NA|NA C Molybdopterin oxidoreductase Fe4S4 domain MAG.T2.42_00527 448385.sce4701 2.5e-44 186.0 Bacteria napB ko:K02568 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798 RC02812 ko00000,ko00001,ko00002 Bacteria COG3043@1,COG3043@2 NA|NA|NA C anaerobic respiration MAG.T2.42_00528 1396141.BATP01000019_gene1679 3e-12 78.2 Verrucomicrobia napF ko:K02572,ko:K02573 ko00000 Bacteria 46WJM@74201,COG1149@1,COG1149@2 NA|NA|NA C 4Fe-4S binding domain MAG.T2.42_00530 523850.TON_1669 2e-103 383.6 Thermococci Archaea 243VV@183968,2Y2AA@28890,COG1297@1,arCOG04807@2157 NA|NA|NA P OPT oligopeptide transporter protein MAG.T2.42_00532 1341157.RF007C_11995 1.3e-42 179.5 Ruminococcaceae ppiB 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,247XN@186801,3WHRC@541000,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.42_00533 1123255.JHYS01000016_gene1091 7.9e-26 125.9 Comamonadaceae 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R14N@1224,2WHZ9@28216,4AIB3@80864,COG2340@1,COG2340@2,COG3055@1,COG3055@2,COG4447@1,COG4447@2 NA|NA|NA S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.42_00535 1142394.PSMK_22380 4.8e-68 265.4 Planctomycetes tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2IXZQ@203682,COG0472@1,COG0472@2 NA|NA|NA M UDP-N-acetylmuramyl pentapeptide MAG.T2.42_00536 926550.CLDAP_15290 2e-86 326.2 Chloroflexi arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011,ko:K12449 ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R01384,R01386,R02984,R07658,R07660 RC00026,RC00289,RC00508,RC01575,RC01811,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 iPC815.YPO2420,iSFV_1184.SFV_2325 Bacteria 2G7TT@200795,COG0451@1,COG0451@2 NA|NA|NA M Male sterility protein MAG.T2.42_00537 1142394.PSMK_22360 6.8e-59 235.7 Planctomycetes 2.7.10.2 ko:K08253,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 2J0AY@203682,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA D Capsular exopolysaccharide family MAG.T2.42_00538 1519464.HY22_02350 3.4e-07 65.1 Chlorobi Bacteria 1FDVB@1090,COG0457@1,COG0457@2 NA|NA|NA S SMART Tetratricopeptide domain protein MAG.T2.42_00539 1142394.PSMK_22340 3.8e-21 109.0 Planctomycetes epsH Bacteria 2IZU8@203682,COG1269@1,COG1269@2 NA|NA|NA C PFAM Transmembrane exosortase (Exosortase_EpsH) MAG.T2.42_00540 1142394.PSMK_22340 1.7e-38 166.8 Planctomycetes epsH Bacteria 2IZU8@203682,COG1269@1,COG1269@2 NA|NA|NA C PFAM Transmembrane exosortase (Exosortase_EpsH) MAG.T2.42_00541 1142394.PSMK_22330 2.9e-75 289.7 Bacteria ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria COG1596@1,COG1596@2 NA|NA|NA M polysaccharide export MAG.T2.42_00543 886293.Sinac_3514 3.2e-20 104.8 Planctomycetes Bacteria 2J0VA@203682,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP MAG.T2.42_00544 237609.PSAKL28_28910 9e-33 146.4 Proteobacteria Bacteria 1N3B7@1224,COG0537@1,COG0537@2 NA|NA|NA FG adenosine 5'-monophosphoramidase activity MAG.T2.42_00545 1142394.PSMK_24160 1.7e-49 202.6 Planctomycetes ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2IXHF@203682,COG1674@1,COG1674@2 NA|NA|NA D COG1674 DNA segregation ATPase FtsK SpoIIIE and related MAG.T2.42_00546 1144275.COCOR_00348 3.7e-07 63.2 Myxococcales Bacteria 1Q9XP@1224,2X4H5@28221,2YZ08@29,434PD@68525,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T2.42_00547 335543.Sfum_1617 2.7e-77 296.6 Deltaproteobacteria Bacteria 1QXGV@1224,2WNC6@28221,42RIF@68525,COG0457@1,COG0457@2 NA|NA|NA S ASPIC and UnbV MAG.T2.42_00548 1265313.HRUBRA_01076 3.5e-47 194.5 unclassified Gammaproteobacteria tadA 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 Bacteria 1JB8J@118884,1RE8P@1224,1S3V3@1236,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase MAG.T2.42_00550 1144275.COCOR_00432 1.4e-118 433.0 Myxococcales 1.1.1.91 ko:K05882 ko00000,ko01000 Bacteria 1MV2Y@1224,2X27R@28221,2YXCB@29,43475@68525,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T2.42_00551 1142394.PSMK_01430 2.5e-99 369.4 Planctomycetes 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 2IYKI@203682,COG2208@1,COG2208@2 NA|NA|NA KT PFAM Stage II sporulation protein E (SpoIIE) MAG.T2.42_00554 926566.Terro_4284 7.4e-74 284.3 Acidobacteriia wbpP 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2JHT7@204432,3Y3ZG@57723,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase MAG.T2.42_00555 1142394.PSMK_01990 3.6e-195 688.0 Planctomycetes atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2IXN5@203682,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit MAG.T2.42_00556 1142394.PSMK_01980 1.8e-25 122.9 Planctomycetes atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2J09A@203682,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T2.42_00557 243090.RB10211 9.7e-12 77.0 Planctomycetes atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2J0VZ@203682,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T2.42_00558 1077285.AGDG01000032_gene4226 1.8e-11 75.5 Bacteroidaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01165 Bacteria 2FTSZ@200643,4ARQC@815,4NURW@976,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T2.42_00559 1142394.PSMK_01950 2.3e-38 166.4 Planctomycetes atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2IZP5@203682,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane MAG.T2.42_00562 1142394.PSMK_11640 1.5e-55 222.6 Planctomycetes nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00338,ko:K02573 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IZAI@203682,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.42_00564 111781.Lepto7376_1205 1.4e-07 63.9 Cyanobacteria ko:K11016 ko03070,map03070 ko00000,ko00001,ko02042,ko02044 Bacteria 1GFRS@1117,COG3210@1,COG3210@2 NA|NA|NA U ABC-type amino acid transport signal transduction systems periplasmic component domain MAG.T2.42_00565 1370125.AUWT01000017_gene2448 2.7e-135 489.6 Mycobacteriaceae engXCA 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183,ko:K20628 ko00500,ko00520,ko01100,map00500,map00520,map01100 R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 GH18,GH5,GH9 Bacteria 2384A@1762,2GJTU@201174,COG2730@1,COG2730@2,COG3469@1,COG3469@2 NA|NA|NA G Belongs to the glycosyl hydrolase 18 family MAG.T2.42_00570 509635.N824_07835 8.1e-14 84.3 Sphingobacteriia Bacteria 1IUNH@117747,2B9NZ@1,3231D@2,4NR0T@976 NA|NA|NA S Protein of unknown function (DUF1579) MAG.T2.42_00571 1118235.CAJH01000023_gene1686 7.9e-17 95.1 Xanthomonadales Bacteria 1PJ0I@1224,1T2HB@1236,1X552@135614,COG4219@1,COG4219@2 NA|NA|NA KT BlaR1 peptidase M56 MAG.T2.42_00572 450851.PHZ_c2204 1.4e-17 96.3 Caulobacterales blaI Bacteria 1N6IF@1224,2KJ0I@204458,2VGMG@28211,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor MAG.T2.42_00573 562970.Btus_0892 1.6e-17 95.1 Firmicutes Bacteria 1VHN9@1239,COG4118@1,COG4118@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module MAG.T2.42_00574 1244869.H261_09247 3.1e-28 131.3 Alphaproteobacteria Bacteria 1N2T0@1224,2VGD6@28211,COG3744@1,COG3744@2 NA|NA|NA S PIN domain MAG.T2.42_00575 344747.PM8797T_24486 3.3e-55 222.2 Planctomycetes dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2IY4W@203682,COG0484@1,COG0484@2 NA|NA|NA O SMART Heat shock protein DnaJ MAG.T2.42_00578 1142394.PSMK_18810 1.2e-41 176.4 Planctomycetes hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 Bacteria 2IZRU@203682,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family MAG.T2.42_00579 232348.ADXL01000014_gene730 3e-24 117.9 Synechococcus Bacteria 1G6S3@1117,1H23Q@1129,COG4634@1,COG4634@2 NA|NA|NA MAG.T2.42_00580 1120956.JHZK01000022_gene1568 6.7e-67 260.8 Alphaproteobacteria yreE Bacteria 1PX74@1224,2TUV9@28211,COG0671@1,COG0671@2 NA|NA|NA I LssY C-terminus MAG.T2.42_00581 1142394.PSMK_26710 3.1e-143 515.4 Planctomycetes gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2IX3U@203682,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T2.42_00583 643867.Ftrac_0888 7e-11 75.5 Cytophagia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 47VB4@768503,4P3WU@976,COG2885@1,COG2885@2 NA|NA|NA M Protein of unknown function (DUF1573) MAG.T2.42_00584 886293.Sinac_6557 1.7e-59 236.1 Planctomycetes trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYUN@203682,COG0512@1,COG0512@2 NA|NA|NA EH TIGRFAM glutamine amidotransferase of anthranilate synthase MAG.T2.42_00585 521674.Plim_2289 1.8e-17 96.7 Planctomycetes ytpQ Bacteria 2J4H3@203682,COG4848@1,COG4848@2 NA|NA|NA S Belongs to the UPF0354 family MAG.T2.42_00586 1303518.CCALI_02907 5.8e-86 325.1 Bacteria Bacteria COG5267@1,COG5267@2 NA|NA|NA S Protein of unknown function (DUF1800) MAG.T2.42_00587 1396141.BATP01000040_gene2102 4.3e-85 322.0 Verrucomicrobiae Bacteria 2IUKB@203494,46T50@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T2.42_00589 1142394.PSMK_20750 1.4e-41 177.2 Planctomycetes nrnA GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 ko:K00974,ko:K06881 ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013 R00188,R00508,R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 2IYQ0@203682,COG0618@1,COG0618@2 NA|NA|NA S phosphoesterase RecJ domain protein MAG.T2.42_00590 314230.DSM3645_11631 3.9e-31 141.7 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_00591 1123508.JH636447_gene7881 4.1e-119 436.0 Planctomycetes Bacteria 2IXZY@203682,COG0515@1,COG0515@2 NA|NA|NA T COG0515 Serine threonine protein MAG.T2.42_00592 1142394.PSMK_20760 2.5e-58 232.6 Planctomycetes ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYZQ@203682,COG0196@1,COG0196@2 NA|NA|NA H riboflavin biosynthesis protein MAG.T2.42_00594 502025.Hoch_4376 3.6e-252 878.2 Deltaproteobacteria glnD 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371 ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020 M00017,M00018 R00243,R01773,R01775 RC00006,RC00087,RC02799 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXNV@1224,2WJWV@28221,42KZZ@68525,COG2844@1,COG2844@2,COG2902@1,COG2902@2 NA|NA|NA E PFAM Glu Leu Phe Val dehydrogenase MAG.T2.42_00595 1384054.N790_12860 9e-54 218.4 Xanthomonadales Bacteria 1MWVZ@1224,1RQBQ@1236,1XCDE@135614,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Lipopolysaccharide kinase (Kdo/WaaP) family MAG.T2.42_00596 1123242.JH636435_gene783 2.1e-11 75.9 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.42_00597 502025.Hoch_6539 5.3e-21 109.4 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_00598 530564.Psta_3105 1.6e-93 349.4 Planctomycetes ypfJ GO:0005575,GO:0005576 ko:K07054 ko00000 Bacteria 2IZ1Y@203682,COG2321@1,COG2321@2 NA|NA|NA S Putative neutral zinc metallopeptidase MAG.T2.42_00599 945713.IALB_1953 4.9e-23 115.2 Bacteria Bacteria COG2353@1,COG2353@2 NA|NA|NA O YceI-like domain MAG.T2.42_00602 1366050.N234_30845 5.5e-65 255.8 Burkholderiaceae mhpA 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 Bacteria 1K0ZF@119060,1MX9R@1224,2VISU@28216,COG0654@1,COG0654@2 NA|NA|NA CH Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) MAG.T2.42_00603 1501391.LG35_00500 5.2e-38 164.9 Rikenellaceae menG 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 22UXJ@171550,2FMI3@200643,4NEDR@976,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) MAG.T2.42_00604 926562.Oweho_0672 2.3e-71 276.2 Flavobacteriia bcsA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576 ko:K16167 ko00000,ko01008 Bacteria 1HX2P@117743,4NDZU@976,COG3424@1,COG3424@2 NA|NA|NA Q PFAM Chalcone and stilbene synthases, N-terminal domain MAG.T2.42_00605 710686.Mycsm_04787 1.4e-108 400.2 Mycobacteriaceae Bacteria 234KQ@1762,2GIUM@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily MAG.T2.42_00606 1121346.KB899810_gene1488 9e-96 357.1 Paenibacillaceae Bacteria 1TPJT@1239,26T0G@186822,4H9KJ@91061,COG1082@1,COG1082@2 NA|NA|NA G xylose isomerase MAG.T2.42_00607 886293.Sinac_1816 4e-71 276.6 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IY1T@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.42_00608 1121875.KB907550_gene945 1.7e-64 253.4 Flavobacteriia Bacteria 1HY72@117743,4NEGD@976,COG2304@1,COG2304@2 NA|NA|NA P von Willebrand factor, type A MAG.T2.42_00609 886293.Sinac_7219 2.4e-51 209.1 Planctomycetes Bacteria 2IZ9J@203682,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T2.42_00611 1267533.KB906733_gene3472 7e-101 375.6 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00612 314230.DSM3645_11631 1.4e-43 183.0 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_00613 497964.CfE428DRAFT_1974 1.1e-230 806.2 Verrucomicrobia nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 46S9D@74201,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source MAG.T2.42_00614 1123514.KB905899_gene479 1e-43 183.3 Thiotrichales dedA Bacteria 1R5SJ@1224,1S99C@1236,463J4@72273,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T2.42_00615 530564.Psta_3453 5.2e-43 181.4 Planctomycetes Bacteria 2IZY6@203682,COG1285@1,COG1285@2 NA|NA|NA S Domain of unknown function (DUF4956) MAG.T2.42_00616 530564.Psta_3452 1e-36 160.6 Planctomycetes Bacteria 2J00S@203682,COG5036@1,COG5036@2 NA|NA|NA P VTC domain MAG.T2.42_00617 1123242.JH636434_gene3999 1.2e-138 500.4 Planctomycetes Bacteria 2IYR8@203682,COG5337@1,COG5337@2 NA|NA|NA M CotH kinase protein MAG.T2.42_00620 251221.35210693 2.2e-29 135.2 Cyanobacteria ko:K06996 ko00000 Bacteria 1G8CB@1117,COG3324@1,COG3324@2 NA|NA|NA S Glyoxalase-like domain MAG.T2.42_00622 742725.HMPREF9450_01201 6.8e-144 518.5 Bacteroidia Bacteria 2FMGG@200643,4NHVP@976,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic MAG.T2.42_00623 502025.Hoch_6539 1.6e-58 235.0 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_00625 1267534.KB906756_gene576 6.6e-58 229.9 Acidobacteriia Bacteria 2JJCM@204432,3Y4PS@57723,COG3193@1,COG3193@2 NA|NA|NA S Haem-degrading MAG.T2.42_00626 1304872.JAGC01000003_gene3013 1.3e-143 516.9 Desulfovibrionales ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1MU37@1224,2M8U3@213115,2WJC1@28221,42MMK@68525,COG0488@1,COG0488@2 NA|NA|NA S PFAM ABC transporter related MAG.T2.42_00628 32057.KB217478_gene4165 6.6e-15 88.2 Nostocales Bacteria 1G2PV@1117,1HIR6@1161,COG0110@1,COG0110@2 NA|NA|NA T PFAM Bacterial transferase hexapeptide (three repeats) MAG.T2.42_00629 1121861.KB899921_gene2983 4.2e-111 407.9 Bacteria 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria COG2227@1,COG2227@2 NA|NA|NA H 3-demethylubiquinone-9 3-O-methyltransferase activity MAG.T2.42_00630 272558.10174370 2.5e-85 323.2 Bacillus ydaH ko:K12942 ko00000 Bacteria 1TPDU@1239,1ZARX@1386,4HAWR@91061,COG2978@1,COG2978@2 NA|NA|NA H AbgT putative transporter family MAG.T2.42_00631 102232.GLO73106DRAFT_00024760 8.9e-83 314.7 Cyanobacteria Bacteria 1G1RS@1117,COG2133@1,COG2133@2 NA|NA|NA G Glucose sorbosone MAG.T2.42_00632 1192034.CAP_8277 2.7e-51 210.3 Myxococcales ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1QZBM@1224,2WQPM@28221,2Z3I2@29,42TG7@68525,COG3266@1,COG3266@2 NA|NA|NA S FG-GAP repeat MAG.T2.42_00633 1267533.KB906733_gene3472 1.8e-90 341.3 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00634 314230.DSM3645_11631 7.8e-44 183.7 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_00635 1142394.PSMK_02820 3.5e-24 117.9 Planctomycetes rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 2J0AM@203682,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation MAG.T2.42_00636 575540.Isop_0679 8.3e-09 66.2 Planctomycetes rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J1A6@203682,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family MAG.T2.42_00637 1128421.JAGA01000002_gene1823 3.6e-11 75.9 unclassified Bacteria yacP ko:K06962 ko00000 Bacteria 2NQ5V@2323,COG3688@1,COG3688@2 NA|NA|NA S YacP-like NYN domain MAG.T2.42_00639 1128421.JAGA01000002_gene1529 3.3e-56 224.9 unclassified Bacteria pdxH 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 iJN678.pdxH Bacteria 2NQT9@2323,COG0259@1,COG0259@2 NA|NA|NA H Pfam:PNPOx_C MAG.T2.42_00640 314230.DSM3645_12851 2.3e-11 76.3 Planctomycetes Bacteria 2F6TW@1,2J3K7@203682,33Z9Z@2 NA|NA|NA MAG.T2.42_00643 1142394.PSMK_24270 0.0 1295.4 Planctomycetes dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IYGA@203682,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III alpha subunit MAG.T2.42_00644 1142394.PSMK_19370 1.2e-75 290.0 Planctomycetes 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IY3N@203682,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family MAG.T2.42_00646 1288826.MSNKSG1_07848 1.9e-125 456.1 Alteromonadaceae fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Bacteria 1MU1X@1224,1RMDE@1236,463YA@72275,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T2.42_00647 1142394.PSMK_22750 4.1e-21 107.1 Planctomycetes acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 2J0V5@203682,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T2.42_00648 1142394.PSMK_22760 1.4e-69 269.6 Planctomycetes Bacteria 2IXE0@203682,COG1028@1,COG1028@2 NA|NA|NA IQ with different specificities (related to short-chain alcohol MAG.T2.42_00650 1142394.PSMK_17270 2.2e-78 299.3 Planctomycetes fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IXX2@203682,COG0331@1,COG0331@2 NA|NA|NA I malonyl CoA-acyl carrier protein transacylase MAG.T2.42_00651 1142394.PSMK_17280 2.7e-82 312.4 Planctomycetes fabH GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681 2.3.1.180 ko:K00648,ko:K11608 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iNJ661.Rv0533c Bacteria 2IXBG@203682,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T2.42_00652 1142394.PSMK_17290 5.8e-106 391.0 Planctomycetes plsX 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 ko:K03621,ko:K21576,ko:K21577 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IWUY@203682,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA MAG.T2.42_00653 1142394.PSMK_17300 4.2e-10 70.1 Bacteria rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family MAG.T2.42_00654 1123508.JH636442_gene4155 1.3e-241 843.2 Planctomycetes putA 1.2.1.88,1.5.5.2 ko:K00294,ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 iAF987.Gmet_3512 Bacteria 2IX0I@203682,COG0506@1,COG0506@2,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T2.42_00655 1142394.PSMK_26830 2.7e-143 515.8 Planctomycetes comM ko:K06400,ko:K07391 ko00000 Bacteria 2IWTT@203682,COG0606@1,COG0606@2 NA|NA|NA O PFAM Magnesium chelatase, ChlI subunit MAG.T2.42_00656 1333507.AUTQ01000170_gene321 4.4e-66 258.8 Gammaproteobacteria Bacteria 1MVAD@1224,1S13M@1236,COG4782@1,COG4782@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF900) MAG.T2.42_00658 102125.Xen7305DRAFT_00025450 5.3e-68 265.8 Bacteria Bacteria COG1225@1,COG1225@2 NA|NA|NA O peroxiredoxin activity MAG.T2.42_00659 344747.PM8797T_25371 4.2e-88 332.4 Planctomycetes ko:K03455 ko00000 2.A.37 Bacteria 2J51D@203682,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T2.42_00665 886293.Sinac_6231 2.8e-102 378.6 Planctomycetes Bacteria 2IYD1@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T2.42_00666 521674.Plim_1960 7.7e-94 350.9 Planctomycetes 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2J2A0@203682,COG0578@1,COG0578@2 NA|NA|NA C FAD dependent oxidoreductase MAG.T2.42_00667 756272.Plabr_2040 4.1e-62 245.0 Planctomycetes Bacteria 2J1QQ@203682,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T2.42_00668 1171373.PACID_01310 3.3e-15 89.7 Propionibacteriales Bacteria 2GWK7@201174,4DP6W@85009,COG1652@1,COG1652@2,COG3170@1,COG3170@2 NA|NA|NA NU LysM domain MAG.T2.42_00669 1142394.PSMK_23630 8.9e-170 604.7 Planctomycetes secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2IYCQ@203682,COG0341@1,COG0341@2,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T2.42_00670 1142394.PSMK_23640 6.2e-14 84.0 Bacteria yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria COG1862@1,COG1862@2 NA|NA|NA U protein transport MAG.T2.42_00671 1142394.PSMK_23650 1.1e-114 420.2 Planctomycetes tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 Bacteria 2IWXI@203682,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) MAG.T2.42_00672 1142394.PSMK_20080 3.1e-24 118.2 Planctomycetes Bacteria 2J1JU@203682,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase MAG.T2.42_00673 671143.DAMO_2146 1.8e-74 286.2 unclassified Bacteria pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 2NNVA@2323,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate MAG.T2.42_00674 1142394.PSMK_05250 1.5e-37 162.9 Planctomycetes yggX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 Bacteria 2J0X4@203682,COG0457@1,COG0457@2,COG2924@1,COG2924@2 NA|NA|NA CO Bacterial Fe(2+) trafficking MAG.T2.42_00675 1235279.C772_02169 9.6e-11 75.1 Planococcaceae yqeZ ko:K07403 ko00000 Bacteria 1TR54@1239,26CYG@186818,4H9P9@91061,COG1030@1,COG1030@2 NA|NA|NA O NfeD-like C-terminal, partner-binding MAG.T2.42_00678 1142394.PSMK_29560 6.7e-68 265.0 Planctomycetes cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2IXYM@203682,COG0617@1,COG0617@2 NA|NA|NA H tRNA nucleotidyltransferase poly(A) polymerase MAG.T2.42_00679 330214.NIDE3611 2e-70 273.1 Bacteria yagE Bacteria COG1723@1,COG1723@2 NA|NA|NA S PFAM Uncharacterised ACR, YagE family COG1723 MAG.T2.42_00680 1142394.PSMK_15810 1.4e-62 246.5 Planctomycetes trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWYG@203682,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate MAG.T2.42_00681 344747.PM8797T_27095 5.7e-19 100.1 Planctomycetes Bacteria 2J047@203682,COG1694@1,COG1694@2 NA|NA|NA S PFAM MazG nucleotide pyrophosphohydrolase MAG.T2.42_00684 1123242.JH636435_gene793 5.2e-169 600.9 Planctomycetes phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 2IZKY@203682,COG0415@1,COG0415@2 NA|NA|NA L FAD binding domain of DNA photolyase MAG.T2.42_00685 926550.CLDAP_00750 1.2e-29 136.7 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.42_00687 926550.CLDAP_00770 1.2e-63 251.9 Chloroflexi Bacteria 2G6X4@200795,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA S PFAM TPR repeat-containing protein MAG.T2.42_00688 42256.RradSPS_0438 5.2e-42 179.1 Actinobacteria bprV ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2GIRE@201174,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_00689 1385517.N800_06325 7.8e-17 95.5 Xanthomonadales MA20_30100 Bacteria 1NMIZ@1224,1RMA2@1236,1X3KI@135614,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T2.42_00692 1268622.AVS7_02164 5.4e-14 84.7 Comamonadaceae rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 1MX7T@1224,2VHR2@28216,4AA53@80864,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.42_00693 861299.J421_0476 1.2e-59 238.4 Gemmatimonadetes Bacteria 1ZTK4@142182,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Tetratricopeptide repeat MAG.T2.42_00694 369723.Strop_2171 0.0 1113.6 Micromonosporales metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM5Q@201174,4DB0D@85008,COG0646@1,COG0646@2,COG1410@1,COG1410@2 NA|NA|NA E Methionine synthase MAG.T2.42_00695 702113.PP1Y_AT19673 8.8e-59 235.0 Sphingomonadales rsbU 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 1MXJQ@1224,2KCKF@204457,2VEZQ@28211,COG2208@1,COG2208@2 NA|NA|NA KT Stage II sporulation E family protein MAG.T2.42_00696 756067.MicvaDRAFT_2380 3.7e-18 98.6 Oscillatoriales Bacteria 1G6GH@1117,1HCJU@1150,COG1917@1,COG1917@2 NA|NA|NA S ChrR Cupin-like domain MAG.T2.42_00697 326427.Cagg_1599 3.7e-10 70.5 Chloroflexi ko:K03088 ko00000,ko03021 Bacteria 2G6UE@200795,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.42_00700 557598.LHK_02902 6.6e-37 161.0 Neisseriales ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 ko00000,ko01000,ko03009 Bacteria 1MW1C@1224,2KPGI@206351,2VIU9@28216,COG0293@1,COG0293@2 NA|NA|NA J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit MAG.T2.42_00701 713587.THITH_03355 2.5e-11 74.3 Chromatiales GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 Bacteria 1N75T@1224,1SD7P@1236,1WZRQ@135613,COG5450@1,COG5450@2 NA|NA|NA K Bacterial antitoxin of type II TA system, VapB MAG.T2.42_00702 380394.Lferr_1289 3.4e-21 107.8 Gammaproteobacteria Bacteria 1MZZ9@1224,1SDG0@1236,COG1487@1,COG1487@2 NA|NA|NA S nucleic acid-binding protein contains PIN domain MAG.T2.42_00703 96561.Dole_2043 1.7e-24 123.2 Desulfobacterales Bacteria 1MZHI@1224,2MN6K@213118,2WUM4@28221,43BRC@68525,COG1800@1,COG1800@2,COG2885@1,COG2885@2,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats MAG.T2.42_00704 240016.ABIZ01000001_gene2298 1.4e-159 569.3 Verrucomicrobiae dapL GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2ITKU@203494,46TMR@74201,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II MAG.T2.42_00705 344747.PM8797T_29178 3.2e-28 132.5 Planctomycetes Bacteria 2J4T8@203682,COG3963@1,COG3963@2 NA|NA|NA I Ribosomal RNA adenine dimethylase MAG.T2.42_00708 485913.Krac_10492 1.7e-23 117.1 Chloroflexi Bacteria 2G7AI@200795,COG4279@1,COG4279@2 NA|NA|NA S zinc finger MAG.T2.42_00709 485913.Krac_10500 1.4e-220 773.5 Chloroflexi helZ 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2G5JY@200795,COG0553@1,COG0553@2 NA|NA|NA L SNF2 Helicase protein MAG.T2.42_00711 1296416.JACB01000002_gene1267 8.3e-17 93.6 Aquimarina ko:K06893 ko00000 Bacteria 1I2R6@117743,2YJMV@290174,4NPEK@976,COG3631@1,COG3631@2 NA|NA|NA S Ketosteroid isomerase-related protein MAG.T2.42_00712 1142394.PSMK_28200 2e-95 355.9 Planctomycetes xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2IX6A@203682,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily MAG.T2.42_00714 1267211.KI669560_gene2870 1.1e-30 140.6 Sphingobacteriia Bacteria 1IXW4@117747,4NNIN@976,COG4760@1,COG4760@2 NA|NA|NA S Bax inhibitor 1 like MAG.T2.42_00716 521674.Plim_0039 9.2e-23 113.2 Planctomycetes yuxK Bacteria 2J432@203682,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 MAG.T2.42_00717 1142394.PSMK_07780 5.5e-158 564.3 Planctomycetes phoH ko:K07175 ko00000 Bacteria 2IYGC@203682,COG1875@1,COG1875@2 NA|NA|NA T PIN domain MAG.T2.42_00718 1192034.CAP_1893 7.4e-70 271.2 Myxococcales yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVUN@1224,2WM6S@28221,2Z0CP@29,42MHJ@68525,COG0327@1,COG0327@2 NA|NA|NA C NIF3 (NGG1p interacting factor 3) MAG.T2.42_00721 439235.Dalk_3029 3.7e-45 188.7 Desulfobacterales 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1MV6M@1224,2MID5@213118,2WM1R@28221,42M5P@68525,COG0553@1,COG0553@2 NA|NA|NA KL SNF2 Helicase protein MAG.T2.42_00722 234267.Acid_4431 5.6e-111 409.1 Bacteria 2.7.11.1 ko:K08884,ko:K12132 ko00000,ko01000,ko01001 Bacteria COG0515@1,COG0515@2,COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T2.42_00723 1192034.CAP_1877 2.7e-105 389.0 Myxococcales 1.3.1.45 ko:K05281 ko00943,ko01110,map00943,map01110 R06562,R06563,R07747,R07751 RC00805 ko00000,ko00001,ko01000 Bacteria 1RBSM@1224,2WTSY@28221,2YX8Q@29,42XUG@68525,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family MAG.T2.42_00724 251221.35214080 4.1e-54 218.8 Cyanobacteria ampC Bacteria 1G434@1117,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T2.42_00725 1142394.PSMK_17230 4.3e-122 445.3 Planctomycetes fleS 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IWYR@203682,COG1716@1,COG1716@2,COG2203@1,COG2203@2,COG4191@1,COG4191@2 NA|NA|NA T GAF domain MAG.T2.42_00726 35754.JNYJ01000019_gene67 2.5e-64 252.3 Actinobacteria Bacteria 2I3BB@201174,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T2.42_00727 756272.Plabr_0939 3.8e-47 194.1 Bacteria Bacteria COG4898@1,COG4898@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2200) MAG.T2.42_00728 1163407.UU7_05087 1.4e-55 222.6 Xanthomonadales csaA ko:K06878 ko00000 Bacteria 1RGC9@1224,1S3G2@1236,1X689@135614,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T2.42_00729 1142394.PSMK_18100 6.9e-67 260.4 Planctomycetes clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2IYFK@203682,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T2.42_00730 1142394.PSMK_28460 1.1e-62 246.5 Planctomycetes clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2IXQN@203682,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T2.42_00731 472759.Nhal_3072 7.6e-49 201.4 Proteobacteria Bacteria 1NGVB@1224,COG5607@1,COG5607@2 NA|NA|NA S PFAM CHAD domain containing protein MAG.T2.42_00732 886293.Sinac_2616 1.8e-123 449.1 Planctomycetes ko:K03924 ko00000,ko01000 Bacteria 2IY1M@203682,COG0714@1,COG0714@2 NA|NA|NA S ATPase associated with MAG.T2.42_00733 886293.Sinac_5609 1.9e-08 65.5 Planctomycetes Bacteria 2EUDC@1,2J1GP@203682,33MVR@2 NA|NA|NA MAG.T2.42_00734 479434.Sthe_2194 8.3e-09 67.8 Bacteria Bacteria COG1225@1,COG1225@2 NA|NA|NA O peroxiredoxin activity MAG.T2.42_00735 1379698.RBG1_1C00001G1631 1.7e-78 300.1 unclassified Bacteria pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2NP8P@2323,COG0006@1,COG0006@2 NA|NA|NA E Metallopeptidase family M24 MAG.T2.42_00736 1267533.KB906735_gene4691 1.2e-59 236.9 Acidobacteriia phhA GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 R01795,R07211 RC00490 ko00000,ko00001,ko01000 Bacteria 2JHN0@204432,3Y3K5@57723,COG3186@1,COG3186@2 NA|NA|NA E Biopterin-dependent aromatic amino acid hydroxylase MAG.T2.42_00737 266117.Rxyl_0619 4e-70 271.9 Rubrobacteria gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2RK@201174,4CPZ9@84995,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding MAG.T2.42_00738 1142394.PSMK_26100 8.7e-18 97.8 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.42_00740 1142394.PSMK_27240 2e-29 137.1 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.42_00741 452637.Oter_0260 9.3e-68 264.2 Opitutae Bacteria 3KA0E@414999,46YS9@74201,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T2.42_00742 395495.Lcho_1250 1.2e-148 533.5 unclassified Burkholderiales phrB GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K06876 ko00000 Bacteria 1KJNW@119065,1MUHX@1224,2VHTR@28216,COG3046@1,COG3046@2 NA|NA|NA S deoxyribodipyrimidine photolyase-related protein MAG.T2.42_00743 1120985.AUMI01000003_gene688 3.9e-63 248.8 Negativicutes ko:K07814 ko00000,ko02022 Bacteria 1UQJH@1239,4H4P2@909932,COG3437@1,COG3437@2 NA|NA|NA T HD domain MAG.T2.42_00744 1173023.KE650771_gene5245 1.7e-24 120.2 Cyanobacteria Bacteria 1G8MF@1117,COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T2.42_00745 240016.ABIZ01000001_gene551 2.4e-87 328.6 Verrucomicrobiae yhhW ko:K06911 ko00000 Bacteria 2IU6M@203494,46SRJ@74201,COG1741@1,COG1741@2 NA|NA|NA S Pirin MAG.T2.42_00746 1122599.AUGR01000013_gene793 9e-24 117.1 Oceanospirillales ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1RHH6@1224,1S74Q@1236,1XKPV@135619,COG1463@1,COG1463@2 NA|NA|NA Q Protein of unknown function (DUF3465) MAG.T2.42_00747 1122970.AUHC01000016_gene2605 2.1e-16 92.4 Sphingomonadales ko:K09167 ko00000 Bacteria 1N8GD@1224,2K6MN@204457,2UEFP@28211,COG3402@1,COG3402@2 NA|NA|NA S Bacterial PH domain MAG.T2.42_00748 243090.RB5057 7.2e-74 285.0 Bacteria ko:K08981 ko00000 Bacteria COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain MAG.T2.42_00749 1278073.MYSTI_01663 1.2e-27 129.4 Myxococcales apaG ko:K06195 ko00000 Bacteria 1MZ2Z@1224,2WWZ0@28221,2YVD5@29,431ED@68525,COG2967@1,COG2967@2 NA|NA|NA P ApaG domain MAG.T2.42_00750 756272.Plabr_3401 6.1e-117 427.9 Planctomycetes arsB 1.6.5.3,4.99.1.12 ko:K00341,ko:K02077,ko:K09121,ko:K09796 ko00190,ko01100,map00190,map01100 M00144,M00244 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000,ko03110 3.A.1.15,3.D.1 Bacteria 2IY4X@203682,COG1055@1,COG1055@2,COG4531@1,COG4531@2 NA|NA|NA P COG1055 Na H antiporter NhaD and related arsenite MAG.T2.42_00751 580332.Slit_0253 4.1e-18 100.1 Proteobacteria ko:K06882 ko00000 Bacteria 1R42S@1224,COG0457@1,COG0457@2,COG1305@1,COG1305@2,COG3391@1,COG3391@2,COG4733@1,COG4733@2 NA|NA|NA E fibronectin type III domain protein MAG.T2.42_00753 376733.IT41_15215 5.1e-66 258.8 Paracoccus 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1MV70@1224,2PYYA@265,2VAMY@28211,COG1858@1,COG1858@2 NA|NA|NA C Di-haem cytochrome c peroxidase MAG.T2.42_00754 1121272.KB903272_gene536 1.4e-59 238.0 Micromonosporales ko:K07004 ko00000 Bacteria 2IAAZ@201174,4DBJS@85008,COG2234@1,COG2234@2,COG5276@1,COG5276@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_00755 1142394.PSMK_25140 3.4e-52 211.8 Planctomycetes Bacteria 2IZW1@203682,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T2.42_00757 1142394.PSMK_11760 2.8e-23 114.4 Planctomycetes rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J04T@203682,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family MAG.T2.42_00758 1158292.JPOE01000002_gene3269 5e-95 354.8 unclassified Burkholderiales obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1KJGU@119065,1MUGZ@1224,2VIM2@28216,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control MAG.T2.42_00759 324602.Caur_0279 1.6e-44 186.0 Chloroflexia gmhA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2G6QD@200795,375VE@32061,COG0279@1,COG0279@2 NA|NA|NA G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate MAG.T2.42_00761 237368.SCABRO_03716 5e-25 120.9 Planctomycetes fur GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K03711 ko00000,ko03000 Bacteria 2IZJY@203682,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family MAG.T2.42_00762 653733.Selin_0600 1.1e-29 136.0 Bacteria trxA 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria COG3118@1,COG3118@2 NA|NA|NA O belongs to the thioredoxin family MAG.T2.42_00763 1142394.PSMK_03290 1.1e-58 233.8 Planctomycetes folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYYU@203682,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives MAG.T2.42_00764 1142394.PSMK_05510 6.4e-121 441.4 Planctomycetes aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 ko:K00014,ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1860 Bacteria 2IXKU@203682,COG0169@1,COG0169@2,COG0710@1,COG0710@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) MAG.T2.42_00767 344747.PM8797T_14204 4e-25 121.7 Planctomycetes Bacteria 2J0EH@203682,COG3023@1,COG3023@2 NA|NA|NA V N-acetylmuramoyl-L-alanine amidase MAG.T2.42_00768 1142394.PSMK_29780 1.5e-54 219.9 Planctomycetes Bacteria 2IZHV@203682,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00769 696747.NIES39_O00970 1.5e-32 146.7 Oscillatoriales Bacteria 1G549@1117,1HAJP@1150,28Q3B@1,2ZCKZ@2 NA|NA|NA MAG.T2.42_00770 886293.Sinac_7029 5.5e-102 377.9 Planctomycetes Bacteria 2J121@203682,COG1226@1,COG1226@2 NA|NA|NA P TrkA-N domain MAG.T2.42_00772 886293.Sinac_2556 4e-54 219.2 Planctomycetes ko:K06888,ko:K20948 ko05111,map05111 ko00000,ko00001 Bacteria 2J28Y@203682,COG0526@1,COG0526@2,COG1331@1,COG1331@2 NA|NA|NA CO Peptidase M56 MAG.T2.42_00774 869210.Marky_0532 1.2e-53 218.0 Deinococcus-Thermus nhaP iJN678.sll0556 Bacteria 1WJWE@1297,COG0025@1,COG0025@2,COG0569@1,COG0569@2 NA|NA|NA P COGs COG0025 NhaP-type Na H and K H antiporter MAG.T2.42_00775 391625.PPSIR1_41099 4.1e-89 335.5 Myxococcales atoE ko:K02106 ko02020,map02020 ko00000,ko00001 2.A.73.1 Bacteria 1MV5A@1224,2WITD@28221,2YUZH@29,42PE0@68525,COG2031@1,COG2031@2 NA|NA|NA I Short chain fatty acid transporter MAG.T2.42_00777 1254432.SCE1572_06975 4.7e-89 334.3 Myxococcales hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 1MUQ3@1224,2WMB8@28221,2YWYR@29,42P3K@68525,COG3808@1,COG3808@2 NA|NA|NA C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force MAG.T2.42_00778 1210884.HG799462_gene7906 1.5e-61 243.0 Planctomycetes Bacteria 2IZBD@203682,COG1028@1,COG1028@2 NA|NA|NA IQ Short chain dehydrogenase MAG.T2.42_00779 477974.Daud_1126 1.1e-46 194.1 Peptococcaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPMQ@1239,248QD@186801,2611J@186807,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase MAG.T2.42_00781 335543.Sfum_1456 4.2e-110 405.2 Syntrophobacterales ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 Bacteria 1MUA8@1224,2MQ56@213462,2WK44@28221,42NKZ@68525,COG1538@1,COG1538@2 NA|NA|NA M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT MAG.T2.42_00782 335543.Sfum_1457 0.0 1330.1 Syntrophobacterales ko:K03296 ko00000 2.A.6.2 Bacteria 1MU48@1224,2MR4N@213462,2WJVV@28221,42MF6@68525,COG0841@1,COG0841@2 NA|NA|NA V Protein export membrane protein MAG.T2.42_00783 204669.Acid345_4070 5.4e-87 328.2 Acidobacteriia ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 2JHUA@204432,3Y2UU@57723,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_00784 102125.Xen7305DRAFT_00025450 7.8e-66 258.5 Bacteria Bacteria COG1225@1,COG1225@2 NA|NA|NA O peroxiredoxin activity MAG.T2.42_00785 1205680.CAKO01000040_gene505 1.1e-35 157.9 Alphaproteobacteria ko:K06889 ko00000 Bacteria 1R67P@1224,2U3D5@28211,COG1073@1,COG1073@2 NA|NA|NA S COG1073 Hydrolases of the alpha beta superfamily MAG.T2.42_00786 857087.Metme_0312 6.6e-14 84.7 Gammaproteobacteria Bacteria 1RF4G@1224,1T0P6@1236,293CN@1,2ZQV6@2 NA|NA|NA MAG.T2.42_00787 1303518.CCALI_00783 2.3e-69 269.6 Bacteria Bacteria COG0673@1,COG0673@2 NA|NA|NA S inositol 2-dehydrogenase activity MAG.T2.42_00788 1303518.CCALI_00781 5.9e-25 121.7 Bacteria apbE_1 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria COG1477@1,COG1477@2 NA|NA|NA H protein flavinylation MAG.T2.42_00789 1123242.JH636435_gene2153 6.9e-115 421.0 Planctomycetes Bacteria 2IZAS@203682,COG0671@1,COG0671@2 NA|NA|NA I LssY C-terminus MAG.T2.42_00790 314230.DSM3645_23231 1.1e-46 194.5 Planctomycetes Bacteria 2IXYP@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.42_00792 398578.Daci_3757 1e-21 109.8 Comamonadaceae vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1RJDP@1224,2WGAS@28216,4AJUT@80864,COG1487@1,COG1487@2 NA|NA|NA S PIN domain MAG.T2.42_00793 266265.Bxe_C0443 3.8e-08 63.9 Burkholderiaceae ntrP ko:K18829 ko00000,ko02048 Bacteria 1KA51@119060,1PY54@1224,2WDEE@28216,COG4456@1,COG4456@2 NA|NA|NA L Virulence-associated protein MAG.T2.42_00794 1337936.IJ00_01285 2.6e-161 575.9 Nostocales 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 Bacteria 1G2AS@1117,1HS4D@1161,COG3408@1,COG3408@2 NA|NA|NA G glycogen debranching MAG.T2.42_00795 1458275.AZ34_03825 4.6e-75 288.5 Comamonadaceae gtsD ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 iJN746.PP_1018 Bacteria 1MU3I@1224,2VGZM@28216,4ABW2@80864,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily MAG.T2.42_00796 1122176.KB903532_gene2676 4.6e-23 116.7 Bacteroidetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 4NUFV@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain MAG.T2.42_00797 661478.OP10G_2783 8.4e-149 535.0 Bacteria 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T2.42_00798 760192.Halhy_3940 3.8e-81 308.5 Sphingobacteriia terC ko:K05794 ko00000 Bacteria 1IQW6@117747,4NH7P@976,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC MAG.T2.42_00799 1461577.CCMH01000037_gene100 8.3e-66 257.3 Flavobacteriia terC Bacteria 1HXRT@117743,4NFFD@976,COG0861@1,COG0861@2 NA|NA|NA P membrane protein TerC MAG.T2.42_00800 1380355.JNIJ01000004_gene2769 1.7e-25 125.2 Bacteria Bacteria COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T2.42_00801 926569.ANT_26130 2.5e-49 203.0 Chloroflexi pimB GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 ko:K13668 R11703,R11704 ko00000,ko01000,ko01003 GT4 Bacteria 2G7TE@200795,COG0438@1,COG0438@2 NA|NA|NA M PFAM glycosyl transferase group 1 MAG.T2.42_00802 349161.Dred_1396 1.5e-15 89.7 Bacteria Bacteria COG4627@1,COG4627@2 NA|NA|NA MAG.T2.42_00803 1120919.AUBI01000001_gene3380 4e-66 259.2 Rhodospirillales ko:K03328 ko00000 2.A.66.2 Bacteria 1R9I0@1224,2JURV@204441,2U3NB@28211,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T2.42_00804 497965.Cyan7822_5116 6.5e-64 252.7 Cyanothece 3.4.24.40 ko:K01406,ko:K21449 ko01503,map01503 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 Bacteria 1GC1J@1117,3KJVM@43988,COG2931@1,COG2931@2,COG3210@1,COG3210@2 NA|NA|NA QU Polymorphic membrane protein Chlamydia MAG.T2.42_00805 479434.Sthe_0221 2.7e-16 92.8 Thermomicrobia Bacteria 27YHS@189775,2GA10@200795,308WN@2,arCOG06292@1 NA|NA|NA S Protein of unknown function (DUF429) MAG.T2.42_00806 880073.Calab_0984 3.2e-59 236.1 unclassified Bacteria degQ 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2NQK9@2323,COG0265@1,COG0265@2 NA|NA|NA O Trypsin MAG.T2.42_00807 452637.Oter_3571 2.6e-13 84.3 Bacteria 3.4.21.107 ko:K04771,ko:K08372 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria COG0265@1,COG0265@2 NA|NA|NA O serine-type endopeptidase activity MAG.T2.42_00809 684949.ATTJ01000001_gene1104 4.6e-117 428.3 Bacteria dcuA GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005469,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015138,GO:0015141,GO:0015238,GO:0015291,GO:0015297,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071422,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K07791,ko:K07792 ko02020,map02020 ko00000,ko00001,ko02000 2.A.13.1 iECDH1ME8569_1439.ECDH1ME8569_3996,iEcDH1_1363.EcDH1_3854,iIT341.HP0724 Bacteria COG2704@1,COG2704@2 NA|NA|NA S C4-dicarboxylate transmembrane transporter activity MAG.T2.42_00810 521674.Plim_1395 5.9e-160 570.9 Planctomycetes aspA 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 Bacteria 2J4YC@203682,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus MAG.T2.42_00811 1267535.KB906767_gene2784 5.8e-169 601.3 Acidobacteriia Bacteria 2JIEZ@204432,3Y3QW@57723,COG3387@1,COG3387@2 NA|NA|NA G Domain of unknown function (DUF5127) MAG.T2.42_00812 237368.SCABRO_02587 4.2e-18 100.9 Bacteria fhaB GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T2.42_00813 266117.Rxyl_0133 8.3e-204 717.2 Rubrobacteria copA 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4CPA7@84995,COG2217@1,COG2217@2 NA|NA|NA P heavy metal translocating P-type ATPase MAG.T2.42_00814 1267533.KB906733_gene3472 1.9e-76 294.7 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00815 1267535.KB906767_gene4499 7.8e-47 193.7 Acidobacteriia ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2JJS7@204432,3Y589@57723,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_00816 420324.KI911934_gene170 1.8e-214 752.3 Methylobacteriaceae yfbS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1JS1S@119045,1MU0K@1224,2TSFS@28211,COG0471@1,COG0471@2,COG0490@1,COG0490@2 NA|NA|NA P TrkA-C domain MAG.T2.42_00817 1192868.CAIU01000003_gene275 8.9e-176 623.6 Phyllobacteriaceae ydaH ko:K12942 ko00000 Bacteria 1MUJ1@1224,2U1AP@28211,43NUM@69277,COG2978@1,COG2978@2 NA|NA|NA H AbgT putative transporter family MAG.T2.42_00818 1123386.AUIW01000009_gene1812 1.1e-23 116.3 Deinococcus-Thermus Bacteria 1WKJ4@1297,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T2.42_00819 1500304.JQKY01000003_gene563 1.8e-135 489.2 Rhizobiaceae MA20_17715 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1MV7D@1224,2U0U8@28211,4BDWN@82115,COG2195@1,COG2195@2 NA|NA|NA E Peptidase family M28 MAG.T2.42_00820 931627.MycrhDRAFT_5992 1.5e-12 79.0 Mycobacteriaceae Bacteria 23E41@1762,2GQXF@201174,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T2.42_00821 439496.RBY4I_2234 8.1e-09 68.2 Alphaproteobacteria Bacteria 1P17G@1224,2EQQB@1,2UY4F@28211,33IA8@2 NA|NA|NA MAG.T2.42_00824 1121946.AUAX01000009_gene4532 9.5e-18 97.8 Micromonosporales 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0N@201174,4D9QW@85008,COG1024@1,COG1024@2 NA|NA|NA I enoyl-CoA hydratase MAG.T2.42_00825 1367847.JCM7686_2359 8.6e-34 151.0 Paracoccus 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVEC@1224,2PVBR@265,2TRPS@28211,COG1024@1,COG1024@2 NA|NA|NA I Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA MAG.T2.42_00826 1120972.AUMH01000012_gene66 1.7e-82 313.5 Alicyclobacillaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,278ZW@186823,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) MAG.T2.42_00827 644966.Tmar_1672 6.6e-115 420.6 Clostridia pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iSB619.SA_RS05355,iYO844.BSU14590 Bacteria 1TP3J@1239,249UD@186801,COG0022@1,COG0022@2 NA|NA|NA C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit MAG.T2.42_00828 1000565.METUNv1_00412 7.2e-23 114.4 Betaproteobacteria 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1N0QW@1224,2VVHG@28216,COG0399@1,COG0399@2 NA|NA|NA M 23S rRNA-intervening sequence protein MAG.T2.42_00829 1232410.KI421428_gene1109 1.2e-88 333.6 Desulfuromonadales pdhA GO:0003674,GO:0005488,GO:0005515,GO:0140030,GO:0140032 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5R@1224,2WJY1@28221,42NW8@68525,43UJJ@69541,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component MAG.T2.42_00834 1121957.ATVL01000014_gene1459 6.3e-10 72.4 Cytophagia Bacteria 47VHU@768503,4PHUI@976,COG5563@1,COG5563@2 NA|NA|NA MAG.T2.42_00835 1220551.SCHR_06995 2.2e-71 276.2 Staphylococcaceae ldh 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 Bacteria 1TQU2@1239,4GYH1@90964,4HAB2@91061,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family MAG.T2.42_00836 323261.Noc_1555 2.4e-146 525.4 Chromatiales ko:K06446 ko00930,ko01100,ko01120,map00930,map01100,map01120 R06943 RC00052 ko00000,ko00001,ko01000 Bacteria 1MUDR@1224,1RMMJ@1236,1WWVA@135613,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain MAG.T2.42_00837 517433.PanABDRAFT_3397 1.5e-25 123.6 Pantoea fadJ GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c26730,iETEC_1333.ETEC_2476,iEcE24377_1341.EcE24377A_2637,ic_1306.c2886 Bacteria 1MU9P@1224,1RMZ8@1236,3VXJZ@53335,COG1024@1,COG1024@2,COG1250@1,COG1250@2 NA|NA|NA I Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities MAG.T2.42_00838 1242864.D187_003284 1.3e-52 213.4 Bacteria XK27_02315 Bacteria COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T2.42_00839 96561.Dole_2043 2.8e-10 74.3 Desulfobacterales Bacteria 1MZHI@1224,2MN6K@213118,2WUM4@28221,43BRC@68525,COG1800@1,COG1800@2,COG2885@1,COG2885@2,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats MAG.T2.42_00841 344747.PM8797T_23494 1.2e-109 403.3 Bacteria Bacteria COG1479@1,COG1479@2,COG1637@1,COG1637@2 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures MAG.T2.42_00844 497965.Cyan7822_5116 3.8e-64 253.4 Cyanothece 3.4.24.40 ko:K01406,ko:K21449 ko01503,map01503 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 Bacteria 1GC1J@1117,3KJVM@43988,COG2931@1,COG2931@2,COG3210@1,COG3210@2 NA|NA|NA QU Polymorphic membrane protein Chlamydia MAG.T2.42_00846 1210884.HG799464_gene10823 1.4e-48 199.5 Planctomycetes Bacteria 2IZC3@203682,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM Short-chain dehydrogenase reductase SDR MAG.T2.42_00848 1122222.AXWR01000004_gene1772 6.3e-31 140.6 Deinococcus-Thermus Bacteria 1WMZT@1297,2CVD4@1,32SXD@2 NA|NA|NA MAG.T2.42_00849 1142394.PSMK_23580 1.7e-22 114.0 Planctomycetes fixC 1.3.99.38 ko:K21401 ko00000,ko01000 Bacteria 2IZDK@203682,COG0644@1,COG0644@2 NA|NA|NA C FAD binding domain MAG.T2.42_00850 1142394.PSMK_13500 3.1e-50 205.7 Planctomycetes mqnA 1.21.98.1,4.2.1.151 ko:K07081,ko:K11782,ko:K11784 ko00130,ko01110,map00130,map01110 R08588,R10666 RC02329,RC03232 ko00000,ko00001,ko01000 Bacteria 2IYUW@203682,COG1427@1,COG1427@2 NA|NA|NA H Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.42_00851 314230.DSM3645_09497 5.9e-24 119.4 Planctomycetes ko:K03086,ko:K03087,ko:K03093 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 2IY72@203682,COG0568@1,COG0568@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.42_00853 644548.SCNU_13413 2.9e-38 167.5 Gordoniaceae Bacteria 2GMPZ@201174,4GAH5@85026,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_00854 661478.OP10G_3431 1.1e-103 383.6 Bacteria hipO GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009109,GO:0009111,GO:0009397,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019213,GO:0019439,GO:0019752,GO:0019877,GO:0034641,GO:0042219,GO:0042365,GO:0042558,GO:0042560,GO:0042737,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046451,GO:0046483,GO:0046655,GO:0046657,GO:0046700,GO:0046982,GO:0046983,GO:0050118,GO:0051186,GO:0051187,GO:0071704,GO:0071713,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 3.5.1.32,3.5.1.47,3.5.1.6,3.5.1.87 ko:K01436,ko:K01451,ko:K05823,ko:K06016,ko:K06048,ko:K12940,ko:K12941,ko:K21613 ko00240,ko00300,ko00360,ko01100,ko01110,ko01230,map00240,map00300,map00360,map01100,map01110,map01230 M00046,M00525 R00905,R01424,R02733,R04666 RC00064,RC00096,RC00162,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria COG1473@1,COG1473@2 NA|NA|NA S N-acetyldiaminopimelate deacetylase activity MAG.T2.42_00855 1123242.JH636437_gene6139 7.9e-33 147.1 Planctomycetes Bacteria 2IZSY@203682,COG1186@1,COG1186@2 NA|NA|NA J chain release factor MAG.T2.42_00856 1142394.PSMK_13170 2e-83 316.2 Planctomycetes tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2IXJP@203682,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction MAG.T2.42_00857 1142394.PSMK_06010 3.2e-24 119.0 Bacteria CP_0228 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria COG1579@1,COG1579@2 NA|NA|NA MAG.T2.42_00858 1142394.PSMK_16380 1.7e-27 130.2 Planctomycetes cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2J032@203682,COG4589@1,COG4589@2 NA|NA|NA S Phosphatidate cytidylyltransferase MAG.T2.42_00861 1142394.PSMK_01270 5.5e-18 97.1 Bacteria Bacteria COG3063@1,COG3063@2 NA|NA|NA NU photosynthesis MAG.T2.42_00863 240015.ACP_0707 5e-62 244.6 Acidobacteriia nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2JI6M@204432,3Y3QD@57723,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T2.42_00865 638303.Thal_0406 1.2e-24 119.8 Aquificae moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 2G551@200783,COG0314@1,COG0314@2 NA|NA|NA H molybdopterin MAG.T2.42_00867 42256.RradSPS_1118 4.3e-39 167.9 Rubrobacteria moaB 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 R09726 RC00002 ko00000,ko00001,ko01000 Bacteria 2II28@201174,4CR10@84995,COG0521@1,COG0521@2 NA|NA|NA H May be involved in the biosynthesis of molybdopterin MAG.T2.42_00868 391598.FBBAL38_12475 2.1e-26 126.3 Flavobacteriia Bacteria 1I4J7@117743,2B9NZ@1,3231D@2,4NR0T@976 NA|NA|NA S Protein of unknown function (DUF1579) MAG.T2.42_00869 243090.RB2901 2.6e-61 243.0 Planctomycetes 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IXAS@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.42_00870 1123504.JQKD01000002_gene3616 4.6e-17 94.7 Comamonadaceae rbpA Bacteria 1N6VR@1224,2VW1R@28216,4AEX6@80864,COG0724@1,COG0724@2 NA|NA|NA S PFAM RNP-1 like RNA-binding protein MAG.T2.42_00872 344747.PM8797T_07122 1.4e-35 156.4 Planctomycetes 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2J0XH@203682,COG2365@1,COG2365@2 NA|NA|NA T Protein tyrosine serine phosphatase MAG.T2.42_00873 1142394.PSMK_01710 1.1e-112 414.1 Planctomycetes ko:K02283,ko:K02454,ko:K03220,ko:K03466 ko03070,ko05111,map03070,map05111 M00331,M00332 ko00000,ko00001,ko00002,ko02035,ko02044,ko03036 3.A.12,3.A.15,3.A.6.1 Bacteria 2IXVD@203682,COG1716@1,COG1716@2,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB MAG.T2.42_00877 1142394.PSMK_20590 4.2e-56 224.9 Planctomycetes Bacteria 2CB5F@1,2IXTM@203682,2ZCDM@2 NA|NA|NA MAG.T2.42_00878 1244869.H261_15552 3.4e-18 99.0 Rhodospirillales Bacteria 1MX0S@1224,2DBJ8@1,2JWUE@204441,2TT7Z@28211,2Z9JM@2 NA|NA|NA S NAD-specific glutamate dehydrogenase MAG.T2.42_00882 1142394.PSMK_20970 4.2e-119 435.6 Planctomycetes pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IX0Q@203682,COG0072@1,COG0072@2 NA|NA|NA J Phenylalanyl-tRNA synthetase, beta subunit MAG.T2.42_00883 1449976.KALB_6706 5.4e-19 101.3 Pseudonocardiales fchA Bacteria 2IIRF@201174,4E6A4@85010,COG3404@1,COG3404@2 NA|NA|NA E Formiminotransferase-cyclodeaminase MAG.T2.42_00884 1142394.PSMK_05690 1.3e-25 123.6 Bacteria Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.42_00885 1449080.JQMV01000003_gene63 3.5e-46 193.4 Deinococcus-Thermus dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1WIHX@1297,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T2.42_00887 1142394.PSMK_22190 6.9e-103 380.9 Planctomycetes 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 2IZ4J@203682,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T2.42_00889 1122165.AUHS01000006_gene550 3.7e-279 968.0 Legionellales lmxF_2 ko:K03296 ko00000 2.A.6.2 Bacteria 1JCKK@118969,1MU48@1224,1RMBN@1236,COG0841@1,COG0841@2 NA|NA|NA U AcrB/AcrD/AcrF family MAG.T2.42_00890 1175306.GWL_00030 2.1e-44 187.2 Oxalobacteraceae acrA ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MU78@1224,2VINC@28216,472ID@75682,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_00891 391165.GbCGDNIH1_1456 7.3e-70 271.6 Rhodospirillales Bacteria 1MUA8@1224,2JW2S@204441,2TSN8@28211,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.42_00892 1356852.N008_06350 2.5e-17 96.3 Cytophagia 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 47RRS@768503,4NR16@976,COG2518@1,COG2518@2 NA|NA|NA O Methyltransferase FkbM domain MAG.T2.42_00893 1304872.JAGC01000009_gene570 1.2e-90 340.1 Desulfovibrionales exoO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K16555,ko:K16564 ko00000,ko01000,ko01003 GT2 Bacteria 1R988@1224,2M8JN@213115,2WJPU@28221,42QGX@68525,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.42_00894 1122176.KB903568_gene3477 2.9e-23 116.7 Bacteria avxIA ko:K11016 ko03070,map03070 ko00000,ko00001,ko02042,ko02044 Bacteria COG3210@1,COG3210@2,COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_00895 344747.PM8797T_23024 1.4e-59 236.1 Planctomycetes gpmB Bacteria 2IZ7M@203682,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family MAG.T2.42_00896 420324.KI912022_gene340 0.0 1290.0 Methylobacteriaceae 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 1JT1D@119045,1MW4J@1224,2TRER@28211,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties MAG.T2.42_00897 1210884.HG799475_gene15269 2.9e-227 794.7 Planctomycetes pgm GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711 Bacteria 2IYG0@203682,COG0033@1,COG0033@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, C-terminal domain MAG.T2.42_00898 344747.PM8797T_23029 1.7e-139 503.1 Planctomycetes malQ 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 iJN678.malQ Bacteria 2IXJJ@203682,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase MAG.T2.42_00902 379066.GAU_1291 1.9e-71 276.2 Gemmatimonadetes hbdA 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 ko:K00074,ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1ZSRN@142182,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MAG.T2.42_00903 880073.Calab_1754 1.3e-129 470.7 unclassified Bacteria 3.2.1.4,3.4.21.66 ko:K01179,ko:K08651 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01002,ko03110 GH5,GH9 Bacteria 2NQ6Y@2323,COG1404@1,COG1404@2,COG3291@1,COG3291@2 NA|NA|NA M PKD domain MAG.T2.42_00905 1379270.AUXF01000003_gene3484 9.2e-14 84.0 Gemmatimonadetes ko:K03088 ko00000,ko03021 Bacteria 1ZT3B@142182,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_00906 644966.Tmar_1299 1.4e-95 356.7 Clostridiales incertae sedis citZ 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPS@1239,24865@186801,3WD3X@538999,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain MAG.T2.42_00907 1239962.C943_01492 1.6e-43 183.0 Bacteroidetes cpcT GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017006,GO:0017007,GO:0017009,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K05383 ko00196,ko01100,map00196,map01100 ko00000,ko00001,ko00194 Bacteria 2CCNY@1,2Z877@2,4NR3D@976 NA|NA|NA E CpeT/CpcT family (DUF1001) MAG.T2.42_00908 661478.OP10G_2721 7.7e-90 337.4 Bacteria rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K10440 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family MAG.T2.42_00909 661478.OP10G_2720 3.4e-124 452.2 Bacteria rbsA 3.6.3.17 ko:K10441 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria COG1129@1,COG1129@2 NA|NA|NA G ABC transporter MAG.T2.42_00910 243090.RB11105 4.5e-46 191.8 Planctomycetes Bacteria 2IZ9W@203682,COG3568@1,COG3568@2 NA|NA|NA S PFAM Endonuclease Exonuclease phosphatase MAG.T2.42_00911 358681.BBR47_11890 2.2e-49 203.0 Paenibacillaceae Bacteria 1UZ6C@1239,26WER@186822,4HKQT@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T2.42_00914 243090.RB9128 6.7e-42 177.6 Bacteria Bacteria 29CWT@1,2ZZUX@2 NA|NA|NA S UPF0314 protein MAG.T2.42_00915 452637.Oter_3587 1.2e-42 180.3 Opitutae sirR ko:K03709 ko00000,ko03000 Bacteria 3K8J0@414999,46T7C@74201,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor MAG.T2.42_00916 292459.STH1506 1.5e-82 313.5 Clostridia troA GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K11707 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 1TRKU@1239,247UW@186801,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family MAG.T2.42_00917 1121033.AUCF01000038_gene629 3.2e-94 351.7 Rhodospirillales mntB ko:K11710 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 iYO844.BSU30760 Bacteria 1MW47@1224,2JRB4@204441,2TRJA@28211,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities MAG.T2.42_00918 1121405.dsmv_1926 6e-85 322.4 delta/epsilon subdivisions mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K03709,ko:K09819,ko:K11708,ko:K11709 ko02010,map02010 M00243,M00319 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.15 Bacteria 1MY5X@1224,42WKX@68525,COG1108@1,COG1108@2,COG1321@1,COG1321@2 NA|NA|NA U ABC 3 transport family MAG.T2.42_00919 644283.Micau_4957 7.4e-211 740.7 Micromonosporales otsB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K01087,ko:K16055 ko00500,ko01100,map00500,map01100 R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT20 iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495 Bacteria 2GJAD@201174,4D9PM@85008,COG1877@1,COG1877@2,COG3387@1,COG3387@2 NA|NA|NA G Trehalose-phosphatase MAG.T2.42_00920 196162.Noca_3994 1.7e-132 479.6 Propionibacteriales otsA GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K16055 ko00500,ko01100,map00500,map01100 R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT20 Bacteria 2GMX7@201174,4DNDY@85009,COG0380@1,COG0380@2 NA|NA|NA G Glycosyltransferase family 20 MAG.T2.42_00922 929562.Emtol_1087 2.3e-15 90.9 Cytophagia Bacteria 47KG1@768503,4NI2T@976,COG3292@1,COG3292@2 NA|NA|NA T PFAM Two component regulator propeller MAG.T2.42_00923 314345.SPV1_13177 2.6e-75 289.3 Proteobacteria mscS ko:K16052 ko00000,ko02000 1.A.23.4 Bacteria 1MXD2@1224,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel MAG.T2.42_00925 1123242.JH636435_gene2496 1.8e-23 116.7 Bacteria vasD ko:K11906 ko03070,map03070 M00334 ko00000,ko00001,ko00002,ko02044 3.A.23.1 Bacteria COG3521@1,COG3521@2 NA|NA|NA D Type VI secretion MAG.T2.42_00926 375451.RD1_1240 2e-62 246.9 Roseobacter Bacteria 1PSSA@1224,2P45Z@2433,2VB67@28211,COG4782@1,COG4782@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF900) MAG.T2.42_00927 335543.Sfum_1462 2.4e-26 126.7 Syntrophobacterales Bacteria 1MXPS@1224,2MQSC@213462,2WM6X@28221,42PA3@68525,COG3064@1,COG3064@2 NA|NA|NA M Protein of unknown function (DUF3300) MAG.T2.42_00928 639283.Snov_4208 2.2e-75 289.3 Alphaproteobacteria flgK ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZXB@1224,2TTM8@28211,COG4786@1,COG4786@2 NA|NA|NA N Protein of unknown function (DUF2950) MAG.T2.42_00929 1396418.BATQ01000120_gene3051 7.1e-37 161.4 Verrucomicrobiae Bacteria 2IVV8@203494,46USU@74201,COG4319@1,COG4319@2 NA|NA|NA S ketosteroid isomerase MAG.T2.42_00932 177439.DP0203 1e-06 60.5 Deltaproteobacteria ko:K03286 ko00000,ko02000 1.B.6 Bacteria 1R3Z1@1224,2WQZ1@28221,42T5M@68525,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T2.42_00933 706587.Desti_2502 0.0 1369.8 Syntrophobacterales 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2MRGT@213462,2WJRD@28221,42PRE@68525,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T2.42_00934 1038860.AXAP01000101_gene5274 0.0 1389.0 Bradyrhizobiaceae 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2TTXG@28211,3JVJZ@41294,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T2.42_00935 595460.RRSWK_01896 5.4e-92 344.7 Planctomycetes pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 2IX8W@203682,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family MAG.T2.42_00936 1163409.UUA_03883 2.6e-168 598.6 Xanthomonadales amnC 1.2.1.32,1.2.1.60,1.2.1.85 ko:K00151,ko:K10217 ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00569 R02762,R03889,R04418,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,1RMBQ@1236,1X3DG@135614,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T2.42_00937 1237149.C900_03218 8.8e-70 270.4 Cytophagia Bacteria 47JB0@768503,4NICN@976,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM Short-chain dehydrogenase reductase SDR MAG.T2.42_00938 1340493.JNIF01000003_gene2885 7.4e-21 107.1 Acidobacteria yuaD Bacteria 3Y820@57723,COG2258@1,COG2258@2 NA|NA|NA S PFAM MOSC domain MAG.T2.42_00939 1121377.KB906407_gene982 4.9e-14 84.7 Deinococcus-Thermus mobA 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 R11581 ko00000,ko00001,ko01000 Bacteria 1WIB6@1297,COG0746@1,COG0746@2 NA|NA|NA H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor MAG.T2.42_00940 1142394.PSMK_27020 5.8e-65 255.0 Bacteria Bacteria COG1363@1,COG1363@2 NA|NA|NA G aminopeptidase activity MAG.T2.42_00941 1142394.PSMK_00420 1.9e-92 346.3 Planctomycetes ribB 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0516,iJN746.PP_3813 Bacteria 2IWX5@203682,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate MAG.T2.42_00942 55207.KP22_13845 2.1e-47 196.1 Pectobacterium ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1MS99@122277,1R9ZQ@1224,1RP9U@1236,COG0652@1,COG0652@2 NA|NA|NA M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.42_00943 1142394.PSMK_15120 1.2e-49 203.8 Planctomycetes proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY5U@203682,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline MAG.T2.42_00944 1142394.PSMK_27470 2.5e-94 352.4 Planctomycetes dus Bacteria 2IYH0@203682,COG0042@1,COG0042@2 NA|NA|NA H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T2.42_00945 497964.CfE428DRAFT_2969 3.9e-117 428.7 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity MAG.T2.42_00948 1303518.CCALI_01222 2.1e-12 79.7 Bacteria Bacteria COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif MAG.T2.42_00949 40571.JOEA01000006_gene4620 5e-25 121.3 Pseudonocardiales sigK ko:K03088 ko00000,ko03021 Bacteria 2GP9D@201174,4E2NI@85010,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.42_00951 318424.EU78_27805 4.8e-14 84.7 Mycobacteriaceae ctaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 iJN678.ctaE Bacteria 233AV@1762,2GKK8@201174,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase, subunit III MAG.T2.42_00952 314230.DSM3645_01951 9.4e-18 96.7 Planctomycetes ctaF 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 ko00000,ko00001,ko00002,ko01000 3.D.4.4 Bacteria 2EAMQ@1,2J0SC@203682,338KI@2 NA|NA|NA S Prokaryotic Cytochrome C oxidase subunit IV MAG.T2.42_00953 1123242.JH636436_gene298 1.7e-57 229.9 Planctomycetes coxC 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 2IYXN@203682,COG1845@1,COG1845@2 NA|NA|NA C Heme copper-type cytochrome quinol oxidase, subunit MAG.T2.42_00954 521674.Plim_3990 2.2e-219 768.5 Planctomycetes coxA 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2IXCQ@203682,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B MAG.T2.42_00955 502025.Hoch_2419 4.3e-61 242.3 Myxococcales coxB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275,ko:K17223 ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120 M00155,M00595 R00081,R10151 RC00016,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1MWHZ@1224,2WM4F@28221,2YWGQ@29,42M7N@68525,COG1622@1,COG1622@2,COG2010@1,COG2010@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T2.42_00956 314230.DSM3645_01971 3.8e-67 261.9 Planctomycetes ko:K07152 ko00000,ko03029 Bacteria 2IYYD@203682,COG1999@1,COG1999@2 NA|NA|NA S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems MAG.T2.42_00958 521674.Plim_3986 1.6e-84 320.1 Planctomycetes actF Bacteria 2IY65@203682,COG4531@1,COG4531@2 NA|NA|NA P ABC-type Zn2 transport system, periplasmic component surface adhesin MAG.T2.42_00959 502025.Hoch_2415 1.1e-45 190.3 Myxococcales actE Bacteria 1RDVX@1224,2WT1Y@28221,2Z0GX@29,42WYA@68525,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF3341) MAG.T2.42_00960 391625.PPSIR1_01132 1.8e-41 176.0 Myxococcales Bacteria 1RDVX@1224,2WT1Y@28221,2Z0GX@29,42WYA@68525,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF3341) MAG.T2.42_00961 1123242.JH636436_gene291 2e-200 705.3 Planctomycetes actC ko:K00185 ko00000 5.A.3 Bacteria 2IWYN@203682,COG5557@1,COG5557@2 NA|NA|NA C Polysulphide reductase MAG.T2.42_00962 502025.Hoch_2413 9.3e-217 760.8 Myxococcales ko:K00184 ko00000 5.A.3 Bacteria 1MU1B@1224,2WKHA@28221,2YZ1M@29,42NEG@68525,COG0243@1,COG0243@2,COG0437@1,COG0437@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T2.42_00963 344747.PM8797T_11846 9.2e-73 280.0 Planctomycetes mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 2IYYJ@203682,COG3880@1,COG3880@2 NA|NA|NA C Cytochrome c7 and related cytochrome c MAG.T2.42_00964 509190.Cseg_4081 5.1e-07 60.5 Caulobacterales ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 1RD0E@1224,2KGQZ@204458,2U7B0@28211,COG1762@1,COG1762@2 NA|NA|NA G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 MAG.T2.42_00965 1142394.PSMK_10880 2.8e-50 205.7 Planctomycetes tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 2IZ3Q@203682,COG0084@1,COG0084@2 NA|NA|NA L COG0084 Mg-dependent DNase MAG.T2.42_00966 1142394.PSMK_07850 1.1e-27 131.0 Planctomycetes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IZ9K@203682,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes MAG.T2.42_00967 886293.Sinac_5369 4.9e-38 164.5 Planctomycetes tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K04075,ko:K11991 ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko01002,ko01011,ko03016 Bacteria 2IZCA@203682,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) MAG.T2.42_00968 661478.OP10G_1361 1.5e-30 139.8 Bacteria MA20_37750 3.1.3.10 ko:K07025,ko:K20866 ko00010,ko01120,map00010,map01120 R00947 RC00078 ko00000,ko00001,ko01000 Bacteria COG1011@1,COG1011@2 NA|NA|NA S phosphatase activity MAG.T2.42_00969 102125.Xen7305DRAFT_00001700 9.8e-22 112.5 Bacteria Bacteria COG1621@1,COG1621@2,COG3291@1,COG3291@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family MAG.T2.42_00970 62928.azo2690 4.4e-63 248.4 Rhodocyclales Bacteria 1QG9J@1224,2KUG7@206389,2VIRR@28216,COG3597@1,COG3597@2 NA|NA|NA P Tellurite resistance protein TerB MAG.T2.42_00971 1142394.PSMK_21380 8.4e-79 301.2 Planctomycetes truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 ko00000,ko01000,ko03016 Bacteria 2IYMT@203682,COG0585@1,COG0585@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs MAG.T2.42_00972 237368.SCABRO_03862 6.8e-31 140.6 Planctomycetes GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03617,ko:K08999 ko00000 Bacteria 2IZNE@203682,COG1259@1,COG1259@2 NA|NA|NA S Bifunctional nuclease MAG.T2.42_00973 1142394.PSMK_23470 1.4e-170 606.3 Planctomycetes nuoG 1.6.5.3 ko:K00184,ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,5.A.3 Bacteria 2IY04@203682,COG0243@1,COG0243@2,COG1034@1,COG1034@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region MAG.T2.42_00975 1123508.JH636443_gene4582 4.3e-76 291.6 Planctomycetes Bacteria 2IY59@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.42_00976 886293.Sinac_2616 5.1e-99 368.2 Planctomycetes ko:K03924 ko00000,ko01000 Bacteria 2IY1M@203682,COG0714@1,COG0714@2 NA|NA|NA S ATPase associated with MAG.T2.42_00977 886293.Sinac_2617 5.1e-137 495.7 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IXKI@203682,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.42_00978 243090.RB10820 2.5e-23 117.9 Planctomycetes Bacteria 2IYRP@203682,COG3391@1,COG3391@2 NA|NA|NA P RING finger protein MAG.T2.42_00981 1128421.JAGA01000002_gene165 1.6e-72 280.0 unclassified Bacteria moaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 Bacteria 2NP5R@2323,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate MAG.T2.42_00982 1142394.PSMK_07450 8.1e-19 100.5 Planctomycetes Bacteria 2DVHI@1,2J0QY@203682,32UZG@2 NA|NA|NA S PFAM PEGA domain MAG.T2.42_00983 1142394.PSMK_01830 9.7e-79 300.1 Planctomycetes lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 2IYUP@203682,COG1137@1,COG1137@2 NA|NA|NA S ABC-type (unclassified) transport system ATPase MAG.T2.42_00984 1177181.T9A_01603 1e-09 70.1 Oceanospirillales ko:K09940 ko00000 Bacteria 1RET3@1224,1S4H0@1236,1XS9A@135619,COG3296@1,COG3296@2 NA|NA|NA S protein conserved in bacteria MAG.T2.42_00985 1142394.PSMK_14480 6.4e-62 245.0 Planctomycetes tlyC ko:K06189 ko00000,ko02000 9.A.40.1.2 Bacteria 2IZAU@203682,COG1253@1,COG1253@2 NA|NA|NA S COG1253 Hemolysins and related MAG.T2.42_00986 1142394.PSMK_14490 4.7e-18 97.8 Planctomycetes ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2J0MV@203682,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA MAG.T2.42_00990 1192034.CAP_3514 4.3e-21 108.2 Myxococcales ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1RINW@1224,2X3FI@28221,2YVVV@29,4385N@68525,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_00991 1379270.AUXF01000001_gene1941 9.8e-58 232.3 Gemmatimonadetes Bacteria 1ZUHA@142182,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Tetratricopeptide repeat MAG.T2.42_00992 7739.XP_002612951.1 3.7e-35 157.1 Chordata PADI2 GO:0000323,GO:0000785,GO:0001672,GO:0001775,GO:0001959,GO:0001960,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002685,GO:0002686,GO:0002688,GO:0002689,GO:0003674,GO:0003824,GO:0004668,GO:0005102,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0006082,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006338,GO:0006355,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0006996,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009719,GO:0009725,GO:0009755,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010848,GO:0012505,GO:0014070,GO:0016043,GO:0016054,GO:0016192,GO:0016569,GO:0016570,GO:0016597,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019219,GO:0019222,GO:0019538,GO:0019546,GO:0019752,GO:0019827,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030141,GO:0030331,GO:0030334,GO:0030336,GO:0030518,GO:0030520,GO:0030522,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031406,GO:0031410,GO:0031497,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032501,GO:0032502,GO:0032870,GO:0032879,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033993,GO:0034097,GO:0034618,GO:0034622,GO:0034728,GO:0034774,GO:0035257,GO:0035258,GO:0035327,GO:0035578,GO:0036094,GO:0036211,GO:0036230,GO:0036413,GO:0036414,GO:0040012,GO:0040013,GO:0040029,GO:0042119,GO:0042221,GO:0042582,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043401,GO:0043412,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045815,GO:0045893,GO:0045935,GO:0046395,GO:0046872,GO:0046903,GO:0046983,GO:0048096,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0050922,GO:0051128,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051270,GO:0051271,GO:0051276,GO:0051427,GO:0051716,GO:0060205,GO:0060255,GO:0060759,GO:0060761,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070099,GO:0070100,GO:0070887,GO:0071103,GO:0071310,GO:0071345,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0097708,GO:0098727,GO:0099503,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901623,GO:1901624,GO:1902275,GO:1902680,GO:1903506,GO:1903508,GO:1990823,GO:1990830,GO:2000112,GO:2000145,GO:2000146,GO:2000401,GO:2000402,GO:2001141 3.5.3.15 ko:K01481 ko00000,ko01000 Metazoa 2CH50@1,2QVJA@2759,38I5H@33154,3BAGM@33208,3CTFM@33213,47YWV@7711 NA|NA|NA S protein-arginine deiminase activity MAG.T2.42_00993 1142394.PSMK_16630 2.5e-170 605.1 Planctomycetes nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IY7J@203682,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.42_00994 1142394.PSMK_16650 2.4e-42 178.7 Planctomycetes nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 ko:K00334,ko:K00335,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 2IZEQ@203682,COG1905@1,COG1905@2 NA|NA|NA C Thioredoxin-like [2Fe-2S] ferredoxin MAG.T2.42_00996 1142394.PSMK_16690 1.7e-142 512.7 Planctomycetes nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IXJ8@203682,COG1894@1,COG1894@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region MAG.T2.42_00997 1121405.dsmv_1542 5.5e-78 299.7 Desulfobacterales oprM_3 ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 Bacteria 1MUA8@1224,2MJ5Q@213118,2WK44@28221,42NKZ@68525,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.42_00998 288000.BBta_1624 4.5e-26 125.9 Bradyrhizobiaceae ko:K03543 M00701 ko00000,ko00002,ko02000 8.A.1.1 Bacteria 1MU7I@1224,2TS39@28211,3JSDA@41294,COG1566@1,COG1566@2 NA|NA|NA V Biotin-lipoyl like MAG.T2.42_00999 525373.HMPREF0766_13827 2.9e-159 568.2 Sphingobacteriia fbaB GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640 Bacteria 1IPKA@117747,4NEUM@976,COG1830@1,COG1830@2 NA|NA|NA G Aldolase MAG.T2.42_01000 1454004.AW11_03211 8e-115 420.6 Betaproteobacteria Bacteria 1MW38@1224,2VN83@28216,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase MAG.T2.42_01002 886293.Sinac_4653 4.1e-208 731.1 Planctomycetes ko:K14393 ko00000,ko02000 2.A.21.7 Bacteria 2IX2N@203682,COG4147@1,COG4147@2 NA|NA|NA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T2.42_01004 367299.JOEE01000002_gene2418 1.4e-18 99.4 Intrasporangiaceae Bacteria 2IQEW@201174,4FHPT@85021,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor MAG.T2.42_01005 479434.Sthe_0801 8.9e-76 290.8 Thermomicrobia moeB 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 27XM2@189775,2G5Q1@200795,COG0476@1,COG0476@2 NA|NA|NA H ThiF family MAG.T2.42_01006 243090.RB8387 4.1e-23 114.8 Planctomycetes Bacteria 2EPR5@1,2J16K@203682,33HBM@2 NA|NA|NA MAG.T2.42_01008 1121382.JQKG01000056_gene3769 2.8e-14 86.3 Bacteria Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T2.42_01009 1089550.ATTH01000001_gene453 1.8e-27 129.8 Bacteroidetes Bacteria 4NM9E@976,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase MAG.T2.42_01010 1142394.PSMK_14250 5.2e-185 654.8 Planctomycetes rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2IX1J@203682,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs MAG.T2.42_01011 331113.SNE_A06370 4.3e-63 248.1 Chlamydiae 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2JFYF@204428,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T2.42_01012 1142394.PSMK_05800 2.5e-106 392.1 Planctomycetes accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accA Bacteria 2IX7N@203682,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA MAG.T2.42_01013 1142394.PSMK_25130 3.2e-22 113.2 Bacteria ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria COG1734@1,COG1734@2 NA|NA|NA T zinc ion binding MAG.T2.42_01014 1142394.PSMK_25120 1.4e-31 142.9 Planctomycetes lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2J0RI@203682,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins MAG.T2.42_01015 526227.Mesil_1980 5.2e-159 567.8 Deinococcus-Thermus nrfA 1.7.2.2 ko:K03385 ko00910,ko01120,ko05132,map00910,map01120,map05132 M00530 R05712 RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 1WI15@1297,COG3303@1,COG3303@2 NA|NA|NA C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process MAG.T2.42_01016 452637.Oter_4607 3.3e-36 158.3 Opitutae nrfH ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 Bacteria 3K8D9@414999,46T0N@74201,COG3005@1,COG3005@2 NA|NA|NA C TIGRFAM cytochrome c nitrate reductase, small subunit MAG.T2.42_01017 269798.CHU_0526 6e-57 227.6 Cytophagia cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 47PCP@768503,4NH0X@976,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T2.42_01018 583355.Caka_2641 9.7e-38 164.9 Bacteria Bacteria 2C6BE@1,32XBJ@2 NA|NA|NA MAG.T2.42_01020 263358.VAB18032_01830 5.4e-50 204.9 Micromonosporales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GK3I@201174,4D8XT@85008,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T2.42_01021 1142394.PSMK_12440 2.3e-56 226.9 Planctomycetes lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 ko:K02004,ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125,3.A.1.15.3,3.A.1.15.5 Bacteria 2IY15@203682,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component MAG.T2.42_01022 404589.Anae109_2331 1.1e-30 140.2 Myxococcales nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1MU1Q@1224,2WIJS@28221,2YURF@29,42ND6@68525,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T2.42_01023 886293.Sinac_2356 2.2e-48 199.9 Planctomycetes Bacteria 2J02Q@203682,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T2.42_01024 1210884.HG799475_gene15231 2.5e-48 199.1 Planctomycetes surE 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2IXPI@203682,COG0496@1,COG0496@2 NA|NA|NA S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates MAG.T2.42_01026 1111069.TCCBUS3UF1_11240 4.7e-25 122.1 Deinococcus-Thermus mnmE ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1WI11@1297,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 MAG.T2.42_01027 1142394.PSMK_11780 1.1e-51 210.3 Planctomycetes coaX 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 Bacteria 2J0M0@203682,COG1521@1,COG1521@2 NA|NA|NA F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis MAG.T2.42_01028 1266908.AQPB01000022_gene1010 2.8e-51 209.1 Chromatiales dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 Bacteria 1MVAT@1224,1RPU0@1236,1WX40@135613,COG0115@1,COG0115@2 NA|NA|NA EH PFAM Aminotransferase, class IV MAG.T2.42_01029 1168034.FH5T_08655 1.9e-61 242.7 Bacteroidetes sgcQ ko:K06971 ko00000 Bacteria 4P0R6@976,COG0434@1,COG0434@2 NA|NA|NA S BtpA family MAG.T2.42_01031 1210884.HG799466_gene12570 3.5e-77 295.0 Bacteria Bacteria 2CEY7@1,2Z8CG@2 NA|NA|NA S membrane MAG.T2.42_01032 204669.Acid345_1384 1.1e-267 929.1 Acidobacteriia sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2JKAD@204432,3Y6IU@57723,COG1053@1,COG1053@2 NA|NA|NA C Fumarate reductase flavoprotein C-term MAG.T2.42_01033 1210884.HG799466_gene12573 9.9e-108 396.4 Planctomycetes sdhB1 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0247c Bacteria 2J136@203682,COG0479@1,COG0479@2 NA|NA|NA C 2Fe-2S iron-sulfur cluster binding domain MAG.T2.42_01034 1210884.HG799466_gene12574 1.1e-28 133.3 Bacteria Bacteria 2EDAV@1,33776@2 NA|NA|NA MAG.T2.42_01036 1123392.AQWL01000003_gene237 8.4e-40 171.4 Betaproteobacteria Bacteria 1REUR@1224,29MQ2@1,2VXQA@28216,308MT@2 NA|NA|NA MAG.T2.42_01037 661478.OP10G_2722 1.7e-105 389.4 Bacteria rbsB ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria COG1879@1,COG1879@2 NA|NA|NA G ABC-type sugar transport system periplasmic component MAG.T2.42_01038 1123070.KB899261_gene2142 5.8e-97 361.3 Bacteria Bacteria 28HII@1,2Z7TZ@2 NA|NA|NA MAG.T2.42_01039 1173024.KI912148_gene4721 1.1e-97 363.6 Stigonemataceae 1.1.3.46 ko:K16422 ko00261,ko01055,ko01130,map00261,map01055,map01130 R06633 RC00240 ko00000,ko00001,ko01000 Bacteria 1G32Y@1117,1JHC6@1189,COG1304@1,COG1304@2 NA|NA|NA C FMN-dependent dehydrogenase MAG.T2.42_01040 530564.Psta_1178 6.4e-172 610.5 Planctomycetes rafA 3.1.3.1,3.1.3.5,3.2.1.22,3.6.1.45 ko:K01077,ko:K07407,ko:K11751 ko00052,ko00230,ko00240,ko00561,ko00600,ko00603,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00052,map00230,map00240,map00561,map00600,map00603,map00730,map00760,map00790,map01100,map01110,map02020 M00126 R00183,R00511,R00963,R01101,R01103,R01104,R01126,R01194,R01227,R01329,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R02926,R03346,R03634,R04019,R04470,R04620,R05549,R05961,R06091 RC00017,RC00049,RC00059,RC00451 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2IZER@203682,COG1657@1,COG1657@2,COG3345@1,COG3345@2 NA|NA|NA G Carbohydrate esterase, sialic acid-specific acetylesterase MAG.T2.42_01041 215803.DB30_7610 1.4e-28 135.2 Myxococcales Bacteria 1QUEG@1224,2X7D7@28221,2Z3FP@29,43C2M@68525,COG0823@1,COG0823@2,COG4932@1,COG4932@2 NA|NA|NA MU PKD domain MAG.T2.42_01042 864051.BurJ1DRAFT_1891 2e-09 67.4 unclassified Burkholderiales Bacteria 1KMGR@119065,1N75D@1224,2VUBY@28216,COG3636@1,COG3636@2 NA|NA|NA K addiction module antidote protein MAG.T2.42_01045 290397.Adeh_0024 1.1e-190 672.9 Myxococcales proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MU7E@1224,2WJVC@28221,2YU5X@29,42ME5@68525,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) MAG.T2.42_01047 1142394.PSMK_00140 1.4e-46 193.0 Planctomycetes ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZBH@203682,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN MAG.T2.42_01048 502025.Hoch_6539 1.9e-28 134.8 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_01049 1142394.PSMK_06200 3.4e-90 338.6 Planctomycetes lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2IXVE@203682,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives MAG.T2.42_01050 1192124.LIG30_2051 2.8e-15 91.3 Proteobacteria Bacteria 1RB92@1224,COG2706@1,COG2706@2 NA|NA|NA G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.42_01051 1183438.GKIL_3395 2.8e-115 423.3 Cyanobacteria Bacteria 1G3GV@1117,COG0515@1,COG0515@2 NA|NA|NA T serine threonine protein kinase MAG.T2.42_01052 1123508.JH636443_gene4981 1.2e-60 240.4 Planctomycetes rsmH 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2IXPV@203682,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA MAG.T2.42_01053 502025.Hoch_2166 8.4e-15 87.8 Myxococcales Bacteria 1PG5E@1224,2X92K@28221,2Z1JU@29,434XM@68525,COG1652@1,COG1652@2 NA|NA|NA M LysM domain MAG.T2.42_01055 1142394.PSMK_21500 1.6e-83 317.4 Planctomycetes ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2IXEK@203682,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain MAG.T2.42_01056 1040982.AXAL01000015_gene2494 2e-56 226.9 Alphaproteobacteria Bacteria 1MVMG@1224,2TSGE@28211,COG0457@1,COG0457@2 NA|NA|NA U COG0457 FOG TPR repeat MAG.T2.42_01057 384676.PSEEN5405 2.9e-62 246.5 Gammaproteobacteria ydcJ Bacteria 1P16G@1224,1RR9P@1236,COG5383@1,COG5383@2 NA|NA|NA S protein conserved in bacteria MAG.T2.42_01058 1142394.PSMK_26820 1.8e-86 327.8 Planctomycetes Bacteria 2IXFV@203682,COG1452@1,COG1452@2 NA|NA|NA M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane MAG.T2.42_01059 1396141.BATP01000040_gene2109 2.3e-36 158.7 Verrucomicrobiae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU6G@203494,46WUX@74201,COG0452@1,COG0452@2 NA|NA|NA H DNA / pantothenate metabolism flavoprotein MAG.T2.42_01060 1142394.PSMK_03880 8.1e-66 256.9 Planctomycetes clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2IXHI@203682,COG0542@1,COG0542@2 NA|NA|NA O with chaperone activity ATP-binding MAG.T2.42_01061 1122604.JONR01000012_gene3431 4.6e-99 367.5 Xanthomonadales ycaC_1 Bacteria 1MU5N@1224,1RPGX@1236,1X30M@135614,COG1335@1,COG1335@2 NA|NA|NA Q Hydrolase MAG.T2.42_01062 1173263.Syn7502_01580 2.5e-24 119.0 Synechococcus ko:K09932 ko00000 Bacteria 1G5MY@1117,1H1R3@1129,COG3224@1,COG3224@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase MAG.T2.42_01063 886293.Sinac_4438 7.3e-232 810.1 Planctomycetes nfdA Bacteria 2IX0K@203682,COG1574@1,COG1574@2 NA|NA|NA S metal-dependent hydrolase with the TIM-barrel fold MAG.T2.42_01064 1479239.JQMU01000001_gene2509 7.4e-97 361.3 Sphingomonadales astD GO:0003674,GO:0003824,GO:0004029,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 R05049 RC00080 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c20030,iEcHS_1320.EcHS_A1829,ic_1306.c2146 Bacteria 1MV2I@1224,2K13M@204457,2TU8S@28211,COG1012@1,COG1012@2 NA|NA|NA C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate MAG.T2.42_01065 1278073.MYSTI_07060 3.8e-64 252.3 Myxococcales astA 1.2.1.71,2.3.1.109 ko:K00673,ko:K06447 ko00330,ko01100,map00330,map01100 R00832,R05049 RC00004,RC00064,RC00080 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_1875 Bacteria 1MWHC@1224,2WPBD@28221,2YU07@29,42SUP@68525,COG3138@1,COG3138@2 NA|NA|NA E N-succinyltransferase beta subunit MAG.T2.42_01066 1444711.CCJF01000004_gene2406 1.8e-103 383.3 Chlamydiae lat 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 ko:K00821,ko:K03918,ko:K07250,ko:K13524 ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727 M00016,M00027,M00028,M00845 R00457,R00908,R01648,R02283,R04188,R04475 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv3290c Bacteria 2JFWA@204428,COG0160@1,COG0160@2 NA|NA|NA E Aminotransferase class-III MAG.T2.42_01067 1278309.KB907100_gene2135 1.4e-53 217.2 Oceanospirillales cpg2 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 1MUSU@1224,1RNIW@1236,1XHPY@135619,COG0624@1,COG0624@2 NA|NA|NA E Acetylornithine deacetylase MAG.T2.42_01068 247490.KSU1_B0500 5.6e-82 311.2 Planctomycetes dapF 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYCH@203682,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan MAG.T2.42_01069 1142394.PSMK_18850 1.5e-27 131.0 Planctomycetes 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 2J0VM@203682,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T2.42_01071 867903.ThesuDRAFT_01723 7.4e-20 103.2 Clostridiales incertae sedis nifU Bacteria 1VAAU@1239,258QY@186801,3WDPB@538999,COG0694@1,COG0694@2 NA|NA|NA O NifU-like domain MAG.T2.42_01073 742738.HMPREF9460_03384 2.2e-12 79.0 unclassified Clostridiales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,24HB9@186801,268ZM@186813,COG2001@1,COG2001@2 NA|NA|NA K MraZ protein, putative antitoxin-like MAG.T2.42_01074 1142394.PSMK_02460 9.4e-17 93.6 Planctomycetes Bacteria 2J4S0@203682,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain MAG.T2.42_01075 1142394.PSMK_30150 1.1e-78 300.4 Planctomycetes Bacteria 2IYMW@203682,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase MAG.T2.42_01076 469371.Tbis_0161 1.1e-07 64.7 Pseudonocardiales pimB Bacteria 2GMI6@201174,4E7WC@85010,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain MAG.T2.42_01079 575540.Isop_2594 6.9e-10 70.9 Planctomycetes Bacteria 2DQ4A@1,2J0NK@203682,334NN@2 NA|NA|NA S Protein of unknown function (DUF2752) MAG.T2.42_01080 649638.Trad_2284 2e-56 226.5 Deinococcus-Thermus pvdM 3.4.13.19 ko:K01273,ko:K01274 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 1WJQ9@1297,COG2355@1,COG2355@2 NA|NA|NA E PFAM Membrane dipeptidase (Peptidase family M19) MAG.T2.42_01081 1142394.PSMK_26420 3.3e-70 272.3 Planctomycetes aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXAM@203682,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) MAG.T2.42_01082 316274.Haur_0628 9.8e-72 277.7 Chloroflexia pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2G617@200795,37528@32061,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T2.42_01083 314230.DSM3645_08612 1.2e-38 166.4 Planctomycetes rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1604 Bacteria 2IZKI@203682,COG0698@1,COG0698@2 NA|NA|NA G COG0698 Ribose 5-phosphate isomerase RpiB MAG.T2.42_01084 1122207.MUS1_01235 6.5e-13 80.9 Bacteria 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 ko:K01104,ko:K01808,ko:K07566,ko:K20201 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030,R10463 RC00376,RC00434,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 Bacteria COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MAG.T2.42_01089 1244869.H261_07398 3.2e-80 305.8 Rhodospirillales ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 1PQIJ@1224,2JW5Y@204441,2V2XG@28211,COG0859@1,COG0859@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) MAG.T2.42_01090 1123242.JH636436_gene238 1.9e-56 227.3 Planctomycetes Bacteria 2J18J@203682,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T2.42_01091 102125.Xen7305DRAFT_00004000 5.9e-40 172.2 Bacteria ko:K07267 ko00000,ko02000 1.B.19.1 Bacteria COG3659@1,COG3659@2 NA|NA|NA M wide pore channel activity MAG.T2.42_01092 639283.Snov_3895 1.9e-106 392.5 Xanthobacteraceae ansB GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.104 ko:K01424,ko:K22278 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1RCTE@1224,2VG80@28211,3EZ8J@335928,COG0252@1,COG0252@2 NA|NA|NA EJ Asparaginase MAG.T2.42_01093 521674.Plim_1504 1.2e-177 629.8 Bacteria qacA Bacteria COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.42_01094 118166.JH976537_gene77 1.9e-125 455.7 Oscillatoriales glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1G1IK@1117,1H7V2@1150,COG2066@1,COG2066@2 NA|NA|NA E Belongs to the glutaminase family MAG.T2.42_01095 207559.Dde_0670 5.6e-277 960.7 Desulfovibrionales Bacteria 1MU48@1224,2MG2S@213115,2WJ2A@28221,42MQ0@68525,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.42_01096 525897.Dbac_1916 7.3e-41 174.9 Desulfovibrionales Bacteria 1R4JA@1224,2MAGW@213115,2WP8X@28221,42SQN@68525,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_01097 644968.DFW101_3151 3.7e-88 332.8 Desulfovibrionales Bacteria 1NYAK@1224,2MA00@213115,2WMAK@28221,42Q3C@68525,COG1075@1,COG1075@2 NA|NA|NA S Alpha beta hydrolase MAG.T2.42_01098 1038859.AXAU01000002_gene644 7.8e-112 410.6 Bradyrhizobiaceae Bacteria 1MXX2@1224,2U2KZ@28211,3JS95@41294,COG1503@1,COG1503@2 NA|NA|NA J translation release factor activity MAG.T2.42_01100 1125973.JNLC01000014_gene2424 1.1e-109 404.1 Bradyrhizobiaceae Bacteria 1N6BY@1224,2TUZY@28211,3JXRH@41294,COG0651@1,COG0651@2 NA|NA|NA CP Proton-conducting membrane transporter MAG.T2.42_01101 395965.Msil_1037 8.2e-136 490.7 Beijerinckiaceae Bacteria 1MURB@1224,2TRQ2@28211,3NCZI@45404,COG0651@1,COG0651@2 NA|NA|NA CP Proton-conducting membrane transporter MAG.T2.42_01102 443598.AUFA01000006_gene3500 5.9e-21 107.1 Bradyrhizobiaceae ko:K05567 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N7TX@1224,2UHUU@28211,3JZES@41294,COG1006@1,COG1006@2 NA|NA|NA P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MAG.T2.42_01103 765911.Thivi_1376 2.7e-73 282.3 Chromatiales Bacteria 1QVK4@1224,1T2WR@1236,1X2P8@135613,COG2111@1,COG2111@2 NA|NA|NA P Domain related to MnhB subunit of Na+/H+ antiporter MAG.T2.42_01104 765911.Thivi_1375 3.7e-22 110.9 Chromatiales ko:K05564,ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N75I@1224,1SCHB@1236,1WYZC@135613,COG1320@1,COG1320@2 NA|NA|NA P PFAM Na H antiporter subunit MAG.T2.42_01105 1121127.JAFA01000002_gene1562 2.2e-07 61.6 Burkholderiaceae ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1KE8Y@119060,1N90U@1224,2W7B3@28216,COG2212@1,COG2212@2 NA|NA|NA P Multiple resistance and pH regulation protein F (MrpF / PhaF) MAG.T2.42_01106 765911.Thivi_1373 1.1e-23 117.1 Chromatiales ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N7MB@1224,1TAHN@1236,1X0YJ@135613,COG1863@1,COG1863@2 NA|NA|NA P Na+/H+ ion antiporter subunit MAG.T2.42_01107 1120949.KB903311_gene694 5.2e-67 261.9 Micromonosporales Bacteria 2IA2X@201174,4DD97@85008,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter MAG.T2.42_01108 420324.KI912022_gene338 8.1e-151 540.0 Alphaproteobacteria glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 1MU19@1224,2U1Z6@28211,COG1523@1,COG1523@2 NA|NA|NA G Alpha amylase, catalytic domain MAG.T2.42_01109 526227.Mesil_0430 7.1e-38 163.7 Deinococcus-Thermus dps GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0006950,GO:0008150,GO:0008199,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 ko:K04047 ko00000,ko03036 Bacteria 1WKH3@1297,COG0783@1,COG0783@2 NA|NA|NA P COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) MAG.T2.42_01110 378806.STAUR_6768 8.5e-260 903.3 Myxococcales lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1MUSW@1224,2WMDY@28221,2YXWJ@29,42Q75@68525,COG1201@1,COG1201@2 NA|NA|NA L DEAD/H associated MAG.T2.42_01111 1550073.JROH01000006_gene1454 5e-11 77.0 Sphingomonadales Bacteria 1N08V@1224,2K35U@204457,2TWNB@28211,COG5373@1,COG5373@2 NA|NA|NA S Predicted membrane protein (DUF2339) MAG.T2.42_01112 414684.RC1_0231 2.7e-73 282.7 Rhodospirillales ko:K14597 ko00906,map00906 R07544,R07546 RC00262 ko00000,ko00001 Bacteria 1MW1E@1224,2JV2D@204441,2U30S@28211,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 21 MAG.T2.42_01113 1231392.OCGS_2159 3.3e-35 155.6 Alphaproteobacteria 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1R787@1224,2U4Y1@28211,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T2.42_01114 1123501.KB902285_gene2135 4.2e-132 478.4 Alphaproteobacteria crtP 1.14.99.44 ko:K10210 ko00906,map00906 R07654,R09671,R09727,R09728 RC00254,RC02089,RC02626,RC02638 ko00000,ko00001,ko01000 Bacteria 1MV2R@1224,2TVAD@28211,COG1233@1,COG1233@2 NA|NA|NA Q TIGRFAM phytoene desaturase MAG.T2.42_01115 1123508.JH636445_gene6501 4.9e-61 242.3 Planctomycetes 1.2.1.3,1.2.99.10 ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZ2G@203682,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.42_01116 240015.ACP_2303 3.1e-132 478.8 Acidobacteriia carC 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 2JI78@204432,3Y3I8@57723,COG1233@1,COG1233@2 NA|NA|NA C TIGRFAM phytoene desaturase MAG.T2.42_01117 1192034.CAP_6184 1.3e-72 280.0 Myxococcales Bacteria 1MU7P@1224,2WIQD@28221,2YU20@29,42NQP@68525,COG0123@1,COG0123@2 NA|NA|NA BQ Histone deacetylase domain MAG.T2.42_01118 1122604.JONR01000025_gene4580 4e-83 314.7 Xanthomonadales kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW68@1224,1RXYM@1236,1X3GY@135614,COG3483@1,COG3483@2 NA|NA|NA E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety MAG.T2.42_01120 314230.DSM3645_09012 9.3e-36 156.8 Planctomycetes kdsC 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IZM6@203682,COG1778@1,COG1778@2 NA|NA|NA S TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family MAG.T2.42_01121 298654.FraEuI1c_5770 3.1e-95 355.5 Frankiales pntA GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2I2FZ@201174,4ERQN@85013,COG3288@1,COG3288@2 NA|NA|NA C PFAM alanine dehydrogenase PNT domain protein MAG.T2.42_01122 1499967.BAYZ01000028_gene1265 3.3e-145 521.9 unclassified Bacteria kamA 5.4.3.2 ko:K01843 ko00310,map00310 R00461 RC00303 ko00000,ko00001,ko01000 Bacteria 2NNY6@2323,COG1509@1,COG1509@2 NA|NA|NA E lysine 2,3-aminomutase activity MAG.T2.42_01123 1121406.JAEX01000011_gene2055 1.5e-103 382.9 Desulfovibrionales ddlA 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1MX3I@1224,2M8FI@213115,2WNIR@28221,42SA1@68525,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family MAG.T2.42_01124 96561.Dole_1891 1.1e-101 377.5 Desulfobacterales ddlA 2.3.1.82,6.3.2.4,6.3.5.5 ko:K01921,ko:K01955,ko:K18815 ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502 M00051 R00256,R00575,R01150,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314 br01600,ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Bacteria 1N4F5@1224,2MHWK@213118,2WKTX@28221,42NYM@68525,COG0454@1,COG0456@2,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family MAG.T2.42_01126 685727.REQ_23620 1e-12 80.9 Nocardiaceae GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K01990,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEU@201174,4FWIY@85025,COG0842@1,COG0842@2,COG1131@1,COG1131@2,COG1716@1,COG1716@2 NA|NA|NA V Forkhead associated domain MAG.T2.42_01128 1142394.PSMK_10260 4.6e-58 231.9 Planctomycetes queG 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 2IX4H@203682,COG1600@1,COG1600@2 NA|NA|NA C Fe-S protein MAG.T2.42_01129 240015.ACP_0812 4.7e-72 278.9 Acidobacteriia crtQ 1.17.8.1,1.3.5.5,1.3.5.6 ko:K00514,ko:K02293,ko:K21677 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R04786,R04787,R04798,R04800,R07510,R07511,R09652,R09653,R09654,R09656,R09658 RC01214,RC01958,RC01959,RC03092,RC03093 ko00000,ko00001,ko00002,ko01000 Bacteria 2JIW6@204432,3Y3PB@57723,COG3349@1,COG3349@2 NA|NA|NA C FAD dependent oxidoreductase MAG.T2.42_01130 240015.ACP_0813 2.9e-49 202.6 Acidobacteriia 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2JIHF@204432,3Y3YX@57723,COG1562@1,COG1562@2 NA|NA|NA I PFAM Squalene phytoene synthase MAG.T2.42_01131 530564.Psta_0881 8.4e-57 227.6 Planctomycetes hpnC 2.5.1.32,2.5.1.99,4.2.3.156 ko:K02291,ko:K21679 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IXUP@203682,COG1562@1,COG1562@2 NA|NA|NA I Squalene phytoene synthase MAG.T2.42_01132 575540.Isop_2276 1.2e-107 396.7 Planctomycetes ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2IXK4@203682,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T2.42_01133 1142394.PSMK_20090 3.4e-110 405.2 Planctomycetes rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2IXW1@203682,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T2.42_01139 478741.JAFS01000001_gene1391 8.5e-53 216.1 unclassified Verrucomicrobia iorA 1.2.7.11,1.2.7.3,1.2.7.8 ko:K00175,ko:K04090 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 37FUX@326457,46VFZ@74201,COG1014@1,COG1014@2,COG4231@1,COG4231@2 NA|NA|NA C Pyruvate ferredoxin/flavodoxin oxidoreductase MAG.T2.42_01140 1142394.PSMK_07400 1.3e-27 130.6 Planctomycetes yidA Bacteria 2J0VT@203682,COG0561@1,COG0561@2 NA|NA|NA S TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily MAG.T2.42_01143 55529.EKX55295 2.5e-79 302.8 Eukaryota Eukaryota COG0564@1,KOG1919@2759 NA|NA|NA J pseudouridine synthase activity MAG.T2.42_01145 1173023.KE650771_gene2163 1.4e-20 107.1 Cyanobacteria Bacteria 1GFR6@1117,2E8PN@1,3330T@2 NA|NA|NA MAG.T2.42_01146 1121106.JQKB01000049_gene3069 8.2e-18 98.2 Alphaproteobacteria 2.7.3.13,2.7.9.1,2.7.9.2 ko:K01006,ko:K01007,ko:K22424 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 1R7DS@1224,2U3SK@28211,COG3848@1,COG3848@2 NA|NA|NA T Pyruvate phosphate dikinase MAG.T2.42_01147 452637.Oter_4084 1.5e-101 376.7 Verrucomicrobia pepQ GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 46U30@74201,COG0006@1,COG0006@2 NA|NA|NA E Aminopeptidase P, N-terminal domain MAG.T2.42_01148 502025.Hoch_3377 1.4e-83 317.0 Deltaproteobacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1NRMT@1224,2X6HQ@28221,43B3S@68525,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein MAG.T2.42_01149 502025.Hoch_3378 3.3e-91 342.0 Myxococcales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUX3@1224,2WM7T@28221,2YUI5@29,42MV1@68525,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T2.42_01151 886293.Sinac_4829 2.9e-96 359.0 Planctomycetes 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 2IXA6@203682,COG2199@1,COG2208@1,COG2208@2,COG3706@2 NA|NA|NA T Sigma factor PP2C-like phosphatases MAG.T2.42_01152 886293.Sinac_4830 3.5e-75 288.9 Planctomycetes cheB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 ko:K03412,ko:K03413,ko:K13491 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00509 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 2IY07@203682,COG2201@1,COG2201@2 NA|NA|NA NT CheB methylesterase MAG.T2.42_01153 243233.MCA0831 1.8e-169 603.2 Methylococcales wspE GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3,2.7.7.65 ko:K03407,ko:K11444,ko:K13490 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00509 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1MUAG@1224,1RMS6@1236,1XDPM@135618,COG0643@1,COG0643@2,COG0745@1,COG0745@2,COG2198@1,COG2198@2 NA|NA|NA T Signal transduction histidine kinase, phosphotransfer (Hpt) region MAG.T2.42_01154 1003200.AXXA_27545 2.7e-17 95.5 Alcaligenaceae wspD ko:K03408,ko:K13486,ko:K13489 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 1RIUD@1224,2VSFU@28216,3T7DA@506,COG0835@1,COG0835@2 NA|NA|NA NT COG0835 Chemotaxis signal transduction protein MAG.T2.42_01155 886293.Sinac_4833 3.4e-34 152.9 Planctomycetes wspC 2.1.1.80 ko:K00575,ko:K13486 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 Bacteria 2J2YW@203682,COG0457@1,COG0457@2,COG1352@1,COG1352@2 NA|NA|NA NT Methyltransferase, chemotaxis proteins MAG.T2.42_01156 1121939.L861_06080 1.4e-07 63.2 Proteobacteria MA20_10425 ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1N0A6@1224,COG0835@1,COG0835@2 NA|NA|NA NT PFAM CheW domain protein MAG.T2.42_01157 243233.MCA1674 9.3e-79 301.6 Methylococcales wspA ko:K03406,ko:K13487 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,1S0J1@1236,1XGYS@135618,COG0840@1,COG0840@2 NA|NA|NA NT similarity to SP P39216 MAG.T2.42_01158 1396418.BATQ01000056_gene202 1.5e-26 126.7 Verrucomicrobiae resA ko:K02199 ko00000,ko03110 Bacteria 2IUST@203494,46X6Z@74201,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.42_01159 1142394.PSMK_06840 1.7e-138 499.2 Planctomycetes 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2IWTD@203682,COG0673@1,COG0673@2 NA|NA|NA S PFAM oxidoreductase MAG.T2.42_01160 1463936.JOJI01000002_gene2996 3.7e-118 431.8 Actinobacteria lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T2.42_01163 1206737.BAGF01000081_gene5267 1.2e-11 76.3 Nocardiaceae Bacteria 2EGCD@1,2GR1I@201174,33A46@2,4G2WY@85025 NA|NA|NA MAG.T2.42_01164 1192034.CAP_0445 1.3e-24 121.3 Myxococcales 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1P9A0@1224,2WKI0@28221,2Z1SA@29,42PIM@68525,COG2308@1,COG2308@2 NA|NA|NA S Evidence 4 Homologs of previously reported genes of MAG.T2.42_01165 886293.Sinac_2122 1.3e-138 500.0 Planctomycetes ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 2IXSU@203682,COG2317@1,COG2317@2 NA|NA|NA E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues MAG.T2.42_01166 1197130.BAFM01000001_gene254 2.2e-42 179.1 Halobacteria araC Archaea 23RWT@183963,2XV38@28890,COG0693@1,arCOG00769@2157 NA|NA|NA S intracellular protease amidase MAG.T2.42_01167 240016.ABIZ01000001_gene760 1.5e-31 143.7 Bacteria Bacteria COG0589@1,COG0589@2 NA|NA|NA T AMP binding MAG.T2.42_01168 867903.ThesuDRAFT_01062 2.1e-136 492.7 Clostridiales incertae sedis iolA GO:0003674,GO:0003824,GO:0004491,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,247W7@186801,3WDC3@538999,COG1012@1,COG1012@2 NA|NA|NA C PFAM Aldehyde dehydrogenase family MAG.T2.42_01171 530564.Psta_3927 9.3e-28 132.1 Planctomycetes 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IYZW@203682,COG0265@1,COG0265@2 NA|NA|NA O typically periplasmic contain C-terminal PDZ domain MAG.T2.42_01172 1174528.JH992898_gene5232 1.7e-18 101.3 Cyanobacteria Bacteria 1GFR6@1117,2E8PN@1,3330T@2 NA|NA|NA MAG.T2.42_01173 631362.Thi970DRAFT_02924 6e-61 240.7 Chromatiales can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273,iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Bacteria 1NGFN@1224,1RSY6@1236,1WY3E@135613,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T2.42_01177 530564.Psta_1982 4.2e-15 87.8 Planctomycetes ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2J3QF@203682,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR MAG.T2.42_01178 1122139.KB907872_gene2280 4e-09 68.2 Oceanospirillales exbD ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 1RI4M@1224,1S4GX@1236,1XKR8@135619,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer MAG.T2.42_01179 530564.Psta_1989 1.4e-35 156.8 Planctomycetes ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2J2RX@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family MAG.T2.42_01181 314230.DSM3645_19318 1.7e-22 113.6 Planctomycetes ko:K02674,ko:K07114 ko00000,ko02000,ko02035,ko02044 1.A.13.2.2,1.A.13.2.3 Bacteria 2J0MU@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain MAG.T2.42_01182 1142394.PSMK_22410 8.4e-75 287.0 Planctomycetes pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2IWYC@203682,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP MAG.T2.42_01183 1142394.PSMK_27240 8.1e-39 168.3 Planctomycetes Bacteria 2J4WW@203682,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T2.42_01184 1162668.LFE_1980 9.6e-17 92.8 Bacteria Bacteria COG5606@1,COG5606@2 NA|NA|NA MAG.T2.42_01185 1173020.Cha6605_1035 2.1e-13 81.3 Cyanobacteria Bacteria 1G6VG@1117,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) MAG.T2.42_01186 1123256.KB907947_gene2648 8.7e-86 323.9 Xanthomonadales int ko:K04763 ko00000,ko03036 Bacteria 1MVAN@1224,1RMSS@1236,1X3FD@135614,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.42_01188 644283.Micau_3865 2.9e-20 107.5 Micromonosporales 1.16.3.3 ko:K22350 ko00000,ko01000 Bacteria 2I71F@201174,4DKYH@85008,COG0823@1,COG0823@2,COG2304@1,COG2304@2,COG3292@1,COG3292@2,COG3391@1,COG3391@2 NA|NA|NA T Involved in the tonB-independent uptake of proteins MAG.T2.42_01189 1283300.ATXB01000002_gene2888 7.9e-32 144.4 Bacteria Bacteria 2DP87@1,330Z8@2 NA|NA|NA MAG.T2.42_01193 1142394.PSMK_31030 5.1e-80 305.4 Planctomycetes murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2IYP2@203682,COG0728@1,COG0728@2 NA|NA|NA U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane MAG.T2.42_01194 1123242.JH636437_gene5995 6e-175 620.9 Planctomycetes cstA ko:K06200 ko00000 Bacteria 2IWZE@203682,COG1966@1,COG1966@2 NA|NA|NA T Carbon starvation protein MAG.T2.42_01195 314271.RB2654_06439 6.4e-37 162.2 Alphaproteobacteria Bacteria 1MU7T@1224,2TRVY@28211,COG2931@1,COG2931@2 NA|NA|NA Q COG2931 RTX toxins and related Ca2 -binding proteins MAG.T2.42_01196 234267.Acid_1367 3.2e-31 141.7 Bacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.42_01197 1089550.ATTH01000001_gene1831 1.2e-77 298.1 Bacteroidetes Order II. Incertae sedis Bacteria 1FJI6@1100069,4NPN9@976,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01199 1267533.KB906736_gene1196 2.7e-81 309.3 Acidobacteriia argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iJN678.argJ,iLJ478.TM1783 Bacteria 2JKUJ@204432,3Y2PH@57723,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate MAG.T2.42_01200 1267533.KB906733_gene3472 2e-94 354.0 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01201 713587.THITH_09765 3.6e-17 97.4 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG3055@1,COG3055@2,COG5640@1,COG5640@2 NA|NA|NA G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.42_01202 1380391.JIAS01000014_gene2189 1.2e-51 209.5 Rhodospirillales Bacteria 1RA49@1224,2JTSQ@204441,2U2X2@28211,COG1510@1,COG1510@2 NA|NA|NA K MarR family MAG.T2.42_01203 497964.CfE428DRAFT_2363 4.2e-30 137.5 Verrucomicrobia Bacteria 2DN6W@1,32UIF@2,46WNT@74201 NA|NA|NA MAG.T2.42_01204 314230.DSM3645_18466 6.7e-117 427.2 Planctomycetes yfcH ko:K07071 ko00000 Bacteria 2IYWK@203682,COG1090@1,COG1090@2 NA|NA|NA S nucleoside-diphosphate sugar epimerase MAG.T2.42_01208 1123242.JH636435_gene2480 5.9e-21 107.8 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.42_01209 1232437.KL662020_gene700 8.7e-51 208.4 Desulfobacterales ko:K02005 ko00000 Bacteria 1MU8D@1224,2MMGU@213118,2WKAD@28221,42PAC@68525,COG0845@1,COG0845@2 NA|NA|NA M HlyD membrane-fusion protein of T1SS MAG.T2.42_01211 1267533.KB906733_gene3472 1.2e-97 364.8 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01213 1123242.JH636438_gene5844 2e-89 336.3 Planctomycetes Bacteria 2IXQ8@203682,COG1657@1,COG1657@2 NA|NA|NA I Prenyltransferase and squalene oxidase repeat MAG.T2.42_01215 1142394.PSMK_05360 1.6e-26 129.0 Bacteria Bacteria COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T2.42_01216 1142394.PSMK_05350 3.9e-103 382.9 Planctomycetes Bacteria 2IXY5@203682,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor (vWF) type A domain MAG.T2.42_01217 1142394.PSMK_28880 8.7e-36 159.1 Planctomycetes Bacteria 2IWTG@203682,COG2304@1,COG2304@2 NA|NA|NA S Aerotolerance regulator N-terminal MAG.T2.42_01218 1210884.HG799467_gene13431 2.6e-49 202.6 Planctomycetes Bacteria 2IWV6@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.42_01219 70448.A0A090M4S4 1.5e-29 137.9 Chlorophyta Viridiplantae 2CYB0@1,2S3AJ@2759,34I74@3041,37VHI@33090 NA|NA|NA S Aspartyl protease MAG.T2.42_01221 498761.HM1_0138 6.2e-08 66.6 Clostridia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1UHXK@1239,25E6U@186801,COG4733@1,COG4733@2,COG5492@1,COG5492@2 NA|NA|NA N S-layer homology domain MAG.T2.42_01222 1192034.CAP_0288 4.1e-18 98.6 Myxococcales regA GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 ko:K15012 ko02020,map02020 M00523 ko00000,ko00001,ko00002,ko02022 Bacteria 1RD7J@1224,2WV25@28221,2YV5R@29,42ZS1@68525,COG4567@1,COG4567@2 NA|NA|NA T Bacterial regulatory protein, Fis family MAG.T2.42_01223 886293.Sinac_3191 7.4e-52 211.8 Planctomycetes Bacteria 2IXRK@203682,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T2.42_01225 321327.CYA_0280 8e-27 129.4 Bacteria exbB2 ko:K03561,ko:K12287 ko00000,ko02000,ko02044 1.A.30.2.1 Bacteria COG5306@1,COG5306@2 NA|NA|NA MAG.T2.42_01228 755731.Clo1100_3357 3.7e-14 85.5 Clostridiaceae Bacteria 1UZFJ@1239,24DAB@186801,2BW4G@1,2ZAQH@2,36IC8@31979 NA|NA|NA MAG.T2.42_01229 1218084.BBJK01000037_gene3525 5.2e-115 422.2 Burkholderiaceae Bacteria 1K3DC@119060,1MX1Z@1224,2VKEC@28216,COG5164@1,COG5164@2 NA|NA|NA K regulation of DNA-templated transcription, elongation MAG.T2.42_01230 391038.Bphy_5242 6e-74 284.6 Burkholderiaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1K04I@119060,1MX8A@1224,2VJFX@28216,COG0604@1,COG0604@2 NA|NA|NA C Alcohol dehydrogenase zinc-binding domain protein MAG.T2.42_01231 861299.J421_1879 1.3e-143 516.5 Gemmatimonadetes 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1ZT8C@142182,COG1252@1,COG1252@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase MAG.T2.42_01232 1128421.JAGA01000002_gene1394 2.5e-44 185.7 unclassified Bacteria pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 2NR9V@2323,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline MAG.T2.42_01233 1142394.PSMK_07570 5.2e-32 146.4 Planctomycetes Bacteria 2A5PN@1,2J3F8@203682,30UEH@2 NA|NA|NA MAG.T2.42_01234 1142394.PSMK_07580 5.7e-27 127.1 Planctomycetes ko:K10947 ko00000,ko03000 Bacteria 2J1J6@203682,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T2.42_01235 1142394.PSMK_24880 7.9e-36 157.5 Planctomycetes pgl 3.1.1.31,3.5.99.6,5.3.1.9 ko:K01057,ko:K01810,ko:K02564 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00006,M00008,M00114 R00765,R02035,R02739,R02740,R03321 RC00163,RC00376,RC00537,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2J0I5@203682,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MAG.T2.42_01236 309801.trd_1895 5.5e-49 201.4 Thermomicrobia fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 27YBP@189775,2G6BB@200795,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates MAG.T2.42_01237 1142394.PSMK_00010 3.9e-87 328.9 Planctomycetes dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837,GO:2000112 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2IWXU@203682,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T2.42_01238 1142394.PSMK_29610 1.1e-75 290.4 Planctomycetes 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 2IWSW@203682,COG1234@1,COG1234@2 NA|NA|NA S of the beta-lactamase MAG.T2.42_01240 1286106.MPL1_10853 2.2e-29 136.7 Thiotrichales Bacteria 1NUVP@1224,1SNDK@1236,46293@72273,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function, DUF481 MAG.T2.42_01241 935567.JAES01000023_gene2527 2.4e-23 115.2 Xanthomonadales mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1RHG8@1224,1S3PD@1236,1X701@135614,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell MAG.T2.42_01242 314230.DSM3645_11631 1.2e-40 173.3 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_01243 1123508.JH636443_gene5004 9.4e-191 673.3 Planctomycetes Bacteria 2IZSQ@203682,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T2.42_01244 159450.NH14_18975 6.7e-46 191.4 Burkholderiaceae flgK ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1K5PF@119060,1MZXB@1224,2VKSZ@28216,COG4786@1,COG4786@2 NA|NA|NA N Protein of unknown function (DUF2950) MAG.T2.42_01246 635013.TherJR_2324 2.1e-59 236.9 Peptococcaceae ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1TQ2M@1239,24CD5@186801,260VW@186807,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_01249 46234.ANA_C11864 9.9e-13 79.7 Nostocales ko:K19092 ko00000,ko02048 Bacteria 1GM0N@1117,1HSNW@1161,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T2.42_01250 1519464.HY22_01920 5.6e-81 308.1 Bacteria MA20_17565 Bacteria COG0265@1,COG0265@2 NA|NA|NA O serine-type endopeptidase activity MAG.T2.42_01251 1267534.KB906755_gene4464 3.9e-54 218.4 Bacteria Bacteria 2C2X7@1,31WBU@2 NA|NA|NA MAG.T2.42_01252 489825.LYNGBM3L_04690 1.3e-28 132.9 Oscillatoriales vapC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07064 ko00000 Bacteria 1G6FV@1117,1HBMX@1150,COG1848@1,COG1848@2 NA|NA|NA S PIN domain MAG.T2.42_01255 349741.Amuc_1059 2.6e-245 855.5 Verrucomicrobiae czcA ko:K07239,ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1,2.A.6.1.4 Bacteria 2ITM5@203494,46USJ@74201,COG3696@1,COG3696@2 NA|NA|NA P AcrB/AcrD/AcrF family MAG.T2.42_01256 349741.Amuc_1060 7e-15 89.0 Bacteria czcB ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_01257 349741.Amuc_1061 3.6e-21 109.8 Bacteria ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria COG1538@1,COG1538@2 NA|NA|NA MU efflux transmembrane transporter activity MAG.T2.42_01259 926550.CLDAP_30940 1.4e-172 612.8 Chloroflexi ddc 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2G7N6@200795,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain MAG.T2.42_01260 1142394.PSMK_23400 7.8e-48 198.0 Planctomycetes anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 ko:K07106,ko:K09001 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 Bacteria 2IWTZ@203682,COG2103@1,COG2103@2,COG2377@1,COG2377@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate MAG.T2.42_01261 595460.RRSWK_04184 3.1e-157 562.0 Planctomycetes xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IYEE@203682,COG2804@1,COG2804@2 NA|NA|NA NU COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB MAG.T2.42_01265 1192034.CAP_7556 9.9e-88 330.5 Myxococcales rtcA GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 ko:K01974 ko00000,ko01000 Bacteria 1MX7Q@1224,2WKZ3@28221,2YTT5@29,42MZG@68525,COG0430@1,COG0430@2 NA|NA|NA A Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP MAG.T2.42_01266 497964.CfE428DRAFT_5215 1.1e-188 666.4 Verrucomicrobia rtcB 6.5.1.3 ko:K14415 ko00000,ko01000,ko03016 Bacteria 46STD@74201,COG1690@1,COG1690@2 NA|NA|NA S tRNA-splicing ligase RtcB MAG.T2.42_01267 267608.RSc0222 4.5e-191 674.5 Burkholderiaceae rtcR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K14414 ko00000,ko03000 Bacteria 1K578@119060,1MX6U@1224,2VHTV@28216,COG4650@1,COG4650@2 NA|NA|NA K Regulator of RNA terminal phosphate cyclase MAG.T2.42_01268 1142394.PSMK_14780 7.5e-24 118.6 Bacteria tcdA2 ko:K03497,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03000,ko03036,ko04812 Bacteria COG0497@1,COG0497@2 NA|NA|NA L DNA recombination MAG.T2.42_01269 1142394.PSMK_14770 4.1e-85 322.0 Planctomycetes waaM 2.3.1.241,2.3.1.265 ko:K02517,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IY7N@203682,COG1560@1,COG1560@2 NA|NA|NA M Lipid A biosynthesis acyltransferase MAG.T2.42_01270 1142394.PSMK_30130 1.1e-30 139.8 Planctomycetes Bacteria 2IZRH@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.42_01271 1122138.AQUZ01000042_gene3363 1.1e-35 156.4 Propionibacteriales Bacteria 2IHNE@201174,4DQIS@85009,COG0251@1,COG0251@2 NA|NA|NA J YjgF/chorismate_mutase-like, putative endoribonuclease MAG.T2.42_01273 1142394.PSMK_17880 4.3e-09 68.9 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.42_01274 1142394.PSMK_08030 6.7e-52 212.2 Planctomycetes ko:K07403 ko00000 Bacteria 2IWTY@203682,COG1030@1,COG1030@2 NA|NA|NA O ClpP class MAG.T2.42_01275 1142394.PSMK_30750 1.2e-19 103.6 Planctomycetes yqeZ ko:K07403 ko00000 Bacteria 2J0K3@203682,COG1030@1,COG1030@2 NA|NA|NA O Membrane-bound serine protease (ClpP class) MAG.T2.42_01276 696281.Desru_1145 3.3e-72 278.9 Peptococcaceae yqfA Bacteria 1TPTD@1239,24APU@186801,260UQ@186807,COG4864@1,COG4864@2 NA|NA|NA S UPF0365 protein MAG.T2.42_01277 452637.Oter_1765 5.3e-44 184.9 Opitutae Bacteria 3K7C7@414999,46SRA@74201,COG1215@1,COG1215@2 NA|NA|NA M PFAM glycosyl transferase family 2 MAG.T2.42_01280 1142394.PSMK_24810 1.2e-46 193.7 Planctomycetes pphA GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009266,GO:0009628,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:0140096,GO:1901564 3.1.3.16 ko:K07313,ko:K07314 ko00000,ko01000 Bacteria 2IZ5T@203682,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase MAG.T2.42_01281 546271.Selsp_0550 3e-11 75.9 Negativicutes yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,4H47Z@909932,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ MAG.T2.42_01282 521674.Plim_2544 3e-28 132.1 Planctomycetes Bacteria 2IY82@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.42_01283 479434.Sthe_1534 1.9e-38 165.2 Thermomicrobia rnhA 3.1.26.4,4.1.1.44 ko:K01607,ko:K03469 ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030 R03470 RC00938 ko00000,ko00001,ko01000,ko03032 Bacteria 27YG5@189775,2GA0S@200795,COG0599@1,COG0599@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T2.42_01284 1123508.JH636439_gene1032 8.8e-42 177.2 Planctomycetes psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXE7@203682,COG0688@1,COG0688@2 NA|NA|NA I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) MAG.T2.42_01287 1121920.AUAU01000006_gene293 1.2e-234 820.5 Acidobacteria ko:K08676 ko00000,ko01000,ko01002 Bacteria 3Y3BP@57723,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog MAG.T2.42_01290 1358423.N180_01905 2e-63 250.0 Sphingobacteriia 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1IVY6@117747,4NG3D@976,COG1785@1,COG1785@2 NA|NA|NA P Belongs to the alkaline phosphatase family MAG.T2.42_01291 661478.OP10G_4483 9.6e-69 267.3 Bacteria ko:K10440,ko:K17203 ko02010,map02010 M00212,M00590 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 Bacteria COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family MAG.T2.42_01292 794903.OPIT5_17290 1.4e-148 533.1 Opitutae 3.6.3.17 ko:K10441 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 3K90Q@414999,46UQP@74201,COG1129@1,COG1129@2 NA|NA|NA G ATPases associated with a variety of cellular activities MAG.T2.42_01293 1254432.SCE1572_50535 2.6e-61 242.7 Proteobacteria ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 1MU95@1224,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein LacI transcriptional regulator MAG.T2.42_01294 864073.HFRIS_021923 1.6e-22 112.5 Oxalobacteraceae 5.1.3.32 ko:K03534 R10819 RC00563 ko00000,ko01000 Bacteria 1N51C@1224,2VUCC@28216,477K0@75682,COG3254@1,COG3254@2 NA|NA|NA G Pfam:DUF718 MAG.T2.42_01295 1210884.HG799462_gene8813 1.9e-60 240.7 Planctomycetes 1.1.1.1,1.1.99.1,1.2.1.10,1.2.1.18,1.2.1.27,1.2.1.3,3.1.3.3 ko:K00108,ko:K00128,ko:K00140,ko:K04072,ko:K07315 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00562,ko00620,ko00625,ko00626,ko00640,ko00650,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00562,map00620,map00625,map00626,map00640,map00650,map00903,map00981,map01100,map01110,map01120,map01130,map01200,map01220 M00013,M00135,M00555 R00228,R00264,R00623,R00631,R00705,R00706,R00710,R00754,R00904,R00922,R00935,R01025,R01172,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04880,R04903,R05050,R05233,R05234,R05237,R05238,R05286,R06366,R06917,R06927,R08146 RC00004,RC00047,RC00050,RC00071,RC00080,RC00087,RC00088,RC00099,RC00116,RC00184,RC00186,RC00218,RC00242,RC00649,RC00816,RC01195,RC01500,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000,ko03021 Bacteria 2J30Q@203682,COG1012@1,COG1012@2,COG2208@1,COG2208@2 NA|NA|NA KT Sigma factor PP2C-like phosphatases MAG.T2.42_01296 1142394.PSMK_11820 1.4e-132 479.6 Bacteria 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria COG2019@1,COG2019@2 NA|NA|NA F adenylate kinase activity MAG.T2.42_01297 1142394.PSMK_27600 1.8e-40 172.9 Planctomycetes truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2IYSC@203682,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T2.42_01303 1166018.FAES_2922 4.3e-41 176.4 Bacteroidetes XK27_02140 ko:K07004 ko00000 Bacteria 4NHB6@976,COG2374@1,COG2374@2 NA|NA|NA G Cellulose binding domain MAG.T2.42_01304 1192034.CAP_3514 5.9e-47 194.1 Myxococcales ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1RINW@1224,2X3FI@28221,2YVVV@29,4385N@68525,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_01305 1267533.KB906733_gene3472 7.8e-90 339.7 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01306 1267533.KB906733_gene3472 4.4e-67 263.1 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01307 521674.Plim_0986 1.1e-16 93.6 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.42_01308 338963.Pcar_2781 6e-111 407.9 delta/epsilon subdivisions ynbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 ko:K01090 ko00000,ko01000 Bacteria 1QSUD@1224,42TZH@68525,COG0671@1,COG0671@2,COG2453@1,COG2453@2 NA|NA|NA IT Dual specificity phosphatase, catalytic domain MAG.T2.42_01309 323261.Noc_1728 5e-169 601.3 Gammaproteobacteria ynbC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 Bacteria 1MWF5@1224,1RNQR@1236,COG2267@1,COG2267@2 NA|NA|NA I Lysophospholipase MAG.T2.42_01310 497964.CfE428DRAFT_0666 2.5e-64 252.3 Bacteria 2.3.1.51,6.2.1.3 ko:K00655,ko:K01897 ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086,M00089 R01280,R02241,R09381 RC00004,RC00014,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria COG0204@1,COG0204@2 NA|NA|NA I Acyl-transferase MAG.T2.42_01311 1121861.KB899912_gene967 3.9e-70 271.9 Alphaproteobacteria cdsA 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX58@1224,2TT9I@28211,COG4589@1,COG4589@2 NA|NA|NA S Phosphatidate cytidylyltransferase MAG.T2.42_01312 886293.Sinac_7155 2.9e-41 175.6 Bacteria pgsAb 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T2.42_01313 1142394.PSMK_20830 7.7e-40 170.6 Planctomycetes 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2IZQ1@203682,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T2.42_01314 1316936.K678_05813 2.7e-17 95.5 Rhodospirillales pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1MZJA@1224,2JTIM@204441,2UGK6@28211,COG1267@1,COG1267@2 NA|NA|NA I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) MAG.T2.42_01316 266117.Rxyl_2770 9e-09 66.6 Bacteria frzZ Bacteria COG0784@1,COG0784@2 NA|NA|NA T Response regulator, receiver MAG.T2.42_01318 1123060.JONP01000024_gene2572 1.8e-106 393.3 Rhodospirillales aldH 1.2.1.26 ko:K13877 ko00040,ko00053,map00040,map00053 R00264 RC00080 ko00000,ko00001,ko01000 Bacteria 1MY2V@1224,2JREB@204441,2TTPR@28211,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.42_01319 1242864.D187_009349 3.2e-76 292.7 Proteobacteria 3.4.11.10 ko:K05994 ko00000,ko01000,ko01002 Bacteria 1R86D@1224,COG2133@1,COG2133@2,COG3291@1,COG3291@2 NA|NA|NA G COG2133 Glucose sorbosone dehydrogenases MAG.T2.42_01321 1038869.AXAN01000008_gene4943 3.3e-39 168.3 Burkholderiaceae Bacteria 1KBGA@119060,1RBUG@1224,2DZKR@1,2VQA7@28216,32VDB@2 NA|NA|NA MAG.T2.42_01322 468059.AUHA01000002_gene706 1.2e-212 746.1 Sphingobacteriia hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_0688 Bacteria 1IR41@117747,4NF2P@976,COG2987@1,COG2987@2 NA|NA|NA E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate MAG.T2.42_01323 1128421.JAGA01000001_gene2194 1.5e-132 479.9 unclassified Bacteria hutH 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 2NNRU@2323,COG2986@1,COG2986@2 NA|NA|NA E Aromatic amino acid lyase MAG.T2.42_01325 1142394.PSMK_02040 2.1e-86 325.9 Planctomycetes adoK GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2683 Bacteria 2IXGC@203682,COG0524@1,COG0524@2 NA|NA|NA H PFAM PfkB MAG.T2.42_01326 1123255.JHYS01000016_gene1091 9e-23 115.9 Comamonadaceae 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R14N@1224,2WHZ9@28216,4AIB3@80864,COG2340@1,COG2340@2,COG3055@1,COG3055@2,COG4447@1,COG4447@2 NA|NA|NA S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.42_01327 1463825.JNXC01000006_gene2153 9.4e-96 357.8 Pseudonocardiales ko:K13277,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2IDJM@201174,4E2D1@85010,COG2304@1,COG2304@2,COG4257@1,COG4257@2 NA|NA|NA V Calx-beta domain MAG.T2.42_01328 1210884.HG799469_gene14157 1.1e-141 510.8 Bacteria 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T2.42_01329 1280380.KR100_08915 2e-65 256.1 Synechococcus murQ GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009254,GO:0016787,GO:0016801,GO:0016803,GO:0016829,GO:0016835,GO:0030203,GO:0043170,GO:0046348,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901575 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 iECH74115_1262.ECH74115_3658,iECSP_1301.ECSP_3375,iECs_1301.ECs3299,iG2583_1286.G2583_2959 Bacteria 1G1DR@1117,1GYHZ@1129,COG2103@1,COG2103@2 NA|NA|NA H Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate MAG.T2.42_01330 649638.Trad_0088 1.1e-149 536.2 Deinococcus-Thermus dys 2.5.1.46 ko:K00809 ko00000,ko01000 Bacteria 1WI9Q@1297,COG1899@1,COG1899@2 NA|NA|NA O Deoxyhypusine synthase MAG.T2.42_01332 99598.Cal7507_4120 6.2e-08 65.5 Cyanobacteria Bacteria 1G0EK@1117,COG3210@1,COG3210@2 NA|NA|NA U TIGRFAM filamentous hemagglutinin family N-terminal domain MAG.T2.42_01333 1210884.HG799463_gene9800 7.8e-179 634.4 Planctomycetes Bacteria 28MCY@1,2IYAJ@203682,2ZAQW@2 NA|NA|NA MAG.T2.42_01334 521674.Plim_1467 6.8e-222 776.5 Planctomycetes Bacteria 2IZB8@203682,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T2.42_01335 391613.RTM1035_05660 1e-81 310.5 Roseovarius Bacteria 1MWK8@1224,2U0YM@28211,46PHJ@74030,COG1594@1,COG1594@2 NA|NA|NA K COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase MAG.T2.42_01339 448385.sce1352 9.2e-203 713.4 Myxococcales kdpA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717 Bacteria 1MV1K@1224,2WJ03@28221,2YWFC@29,42NCD@68525,COG2060@1,COG2060@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane MAG.T2.42_01340 1254432.SCE1572_09215 6.7e-266 923.3 Myxococcales kdpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iAF987.Gmet_2434,iECNA114_1301.ECNA114_0634,iECSF_1327.ECSF_0632 Bacteria 1MU7D@1224,2WJC0@28221,2YWXY@29,42NGX@68525,COG2216@1,COG2216@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system MAG.T2.42_01341 1234364.AMSF01000016_gene1734 1.7e-50 206.1 Xanthomonadales kdpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 Bacteria 1RABG@1224,1S2B0@1236,1X6DA@135614,COG2156@1,COG2156@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex MAG.T2.42_01342 671143.DAMO_0414 9.5e-218 763.8 unclassified Bacteria Bacteria 2NNNV@2323,COG0642@1,COG2205@2 NA|NA|NA T Osmosensitive K+ channel His kinase sensor domain MAG.T2.42_01343 316274.Haur_2274 2.9e-73 282.0 Chloroflexia Bacteria 2G6JP@200795,3773X@32061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal MAG.T2.42_01344 237368.SCABRO_03846 4e-18 98.6 Bacteria ko:K18480 M00669 ko00000,ko00002,ko02000 3.A.1.27.1 Bacteria COG3009@1,COG3009@2 NA|NA|NA Q Protein conserved in bacteria MAG.T2.42_01345 237368.SCABRO_03847 1.3e-45 190.7 Bacteria iamC ko:K02067,ko:K06192 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents, periplasmic component MAG.T2.42_01346 519989.ECTPHS_05085 8.3e-85 320.5 Chromatiales ttg2A ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MUSD@1224,1S1PR@1236,1WY6G@135613,COG1127@1,COG1127@2 NA|NA|NA Q ABC transporter MAG.T2.42_01347 237368.SCABRO_03849 3.3e-88 332.0 Planctomycetes ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IX01@203682,COG0767@1,COG0767@2 NA|NA|NA Q Belongs to the MlaE permease family MAG.T2.42_01348 1142394.PSMK_16160 1.4e-35 156.4 Planctomycetes rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZCC@203682,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA MAG.T2.42_01349 1121448.DGI_2182 3.2e-42 179.9 Desulfovibrionales Bacteria 1NVTE@1224,2F5QV@1,2MF8Y@213115,2WV6K@28221,33Y9Q@2,43001@68525 NA|NA|NA MAG.T2.42_01350 1142394.PSMK_17450 3.4e-39 167.9 Planctomycetes nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IX3H@203682,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen MAG.T2.42_01351 1122939.ATUD01000008_gene2520 5e-41 174.5 Rubrobacteria yjcK 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2IKZC@201174,4CQMP@84995,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T2.42_01356 1142394.PSMK_11260 8.5e-68 263.5 Planctomycetes adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IZRF@203682,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism MAG.T2.42_01357 1142394.PSMK_31510 1.5e-115 423.7 Planctomycetes recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IXVB@203682,COG0608@1,COG0608@2 NA|NA|NA L single-stranded-DNA-specific exonuclease RecJ MAG.T2.42_01358 45157.CMT435CT 5.4e-51 208.4 Eukaryota MCS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0015994,GO:0015995,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 iRC1080.CRv4_Au5_s12_g3144_t1 Eukaryota 2QS77@2759,COG0245@1 NA|NA|NA I 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity MAG.T2.42_01360 1142394.PSMK_14660 1.4e-67 263.8 Planctomycetes murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2IX53@203682,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) MAG.T2.42_01361 358396.C445_21071 9.7e-15 87.8 Halobacteria Archaea 23WPJ@183963,2XYWP@28890,COG0500@1,arCOG01402@2157 NA|NA|NA Q COG0500 SAM-dependent methyltransferases MAG.T2.42_01362 1142394.PSMK_27380 9.6e-97 360.9 Planctomycetes glmM 5.4.2.10,5.4.2.2,5.4.2.8 ko:K01840,ko:K03431,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R02060,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXRS@203682,COG1109@1,COG1109@2 NA|NA|NA G PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain MAG.T2.42_01363 1142394.PSMK_15460 2.7e-19 101.7 Bacteria queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria COG0720@1,COG0720@2 NA|NA|NA H synthase MAG.T2.42_01364 264462.Bd1010 7.9e-215 753.8 Bdellovibrionales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MUM3@1224,2MTKJ@213481,2WJG7@28221,42NN7@68525,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) MAG.T2.42_01372 1142394.PSMK_22320 3.1e-72 278.9 Planctomycetes gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2IWWN@203682,COG0240@1,COG0240@2 NA|NA|NA I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase MAG.T2.42_01373 391625.PPSIR1_04398 1e-17 96.7 Deltaproteobacteria yciA ko:K10806 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1MZAZ@1224,2WQSB@28221,42RJS@68525,COG1607@1,COG1607@2 NA|NA|NA I Thioesterase superfamily MAG.T2.42_01374 1210884.HG799462_gene8044 1e-39 170.2 Planctomycetes purN 2.1.2.2,6.3.2.6,6.3.4.13 ko:K11175,ko:K13713 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04144,R04325,R04326,R04591 RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS04225 Bacteria 2IZ96@203682,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate MAG.T2.42_01375 237368.SCABRO_03118 2.5e-08 67.4 Planctomycetes Bacteria 2J0KQ@203682,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T2.42_01376 1142394.PSMK_02370 2.4e-42 179.5 Planctomycetes Bacteria 2IZGR@203682,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) MAG.T2.42_01377 1117647.M5M_17550 1.2e-12 79.3 unclassified Gammaproteobacteria yhbH ko:K05808 ko00000,ko03009 Bacteria 1J6HN@118884,1MZHW@1224,1S8U1@1236,COG1544@1,COG1544@2 NA|NA|NA J COG1544 Ribosome-associated protein Y (PSrp-1) MAG.T2.42_01378 344747.PM8797T_06922 1.6e-29 136.0 Planctomycetes ptsN 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IZ73@203682,COG1762@1,COG1762@2 NA|NA|NA G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 MAG.T2.42_01379 1469245.JFBG01000002_gene464 2.3e-08 64.3 Gammaproteobacteria ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02784,ko:K08485,ko:K11189 ko02060,map02060 ko00000,ko00001,ko02000 4.A.2.1,8.A.8.1.1 Bacteria 1N6RM@1224,1SCXX@1236,COG1925@1,COG1925@2 NA|NA|NA G Phosphotransferase System MAG.T2.42_01380 649638.Trad_2420 1.1e-175 623.2 Deinococcus-Thermus ggt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 1WI9V@1297,COG0405@1,COG0405@2 NA|NA|NA E PFAM Gamma-glutamyltranspeptidase MAG.T2.42_01381 1142394.PSMK_00940 6.7e-111 407.5 Planctomycetes mnmA 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 2IXFF@203682,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 MAG.T2.42_01382 1142394.PSMK_19530 5.2e-43 181.8 Planctomycetes 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2J4X4@203682,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T2.42_01383 344747.PM8797T_30841 9.9e-23 113.6 Planctomycetes Bacteria 2J0J3@203682,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) MAG.T2.42_01384 449447.MAE_61030 5.6e-32 145.6 Cyanobacteria dcm GO:0003674,GO:0003824,GO:0003886,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044728,GO:0046483,GO:0071704,GO:0090116,GO:0090304,GO:0140097,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1G138@1117,COG0270@1,COG0270@2 NA|NA|NA H PFAM C-5 cytosine-specific DNA methylase MAG.T2.42_01385 1487953.JMKF01000069_gene94 2e-102 380.2 Bacteria dnaG 3.6.4.12 ko:K02314,ko:K02316 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T2.42_01386 1142394.PSMK_22290 1.3e-261 909.1 Planctomycetes ko:K02355 ko00000,ko03012,ko03029 Bacteria 2IXUD@203682,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome MAG.T2.42_01387 479434.Sthe_3419 5.2e-10 70.5 Chloroflexi ko:K07075 ko00000 Bacteria 2G76P@200795,COG1669@1,COG1669@2 NA|NA|NA L PFAM DNA polymerase, beta domain protein region MAG.T2.42_01388 394221.Mmar10_1668 9.8e-18 95.9 Hyphomonadaceae Bacteria 1PXUM@1224,2BH9T@1,2UH9D@28211,32BB9@2,43ZXG@69657 NA|NA|NA MAG.T2.42_01389 886293.Sinac_6323 1.7e-11 75.5 Planctomycetes pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01657,ko:K01665,ko:K03342,ko:K13503,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 iEC042_1314.EC042_1977 Bacteria 2IXEN@203682,COG0147@1,COG0147@2 NA|NA|NA EH component I MAG.T2.42_01393 1142394.PSMK_31050 2.4e-32 146.7 Planctomycetes Bacteria 2IZVM@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.42_01394 1142394.PSMK_31040 2.9e-41 177.2 Planctomycetes Bacteria 2IZ6E@203682,COG1305@1,COG1305@2 NA|NA|NA E transglutaminase domain protein MAG.T2.42_01396 292564.Cyagr_0949 1.1e-25 123.2 Cyanobium Bacteria 1G5AK@1117,22SX9@167375,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 MAG.T2.42_01397 1121406.JAEX01000019_gene2776 1.3e-61 244.2 Desulfovibrionales mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 1MW24@1224,2M94B@213115,2WIPC@28221,42MA7@68525,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter MAG.T2.42_01398 1349820.M707_00425 3.3e-48 198.7 Micrococcaceae spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1W83K@1268,2GJ12@201174,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family MAG.T2.42_01400 28737.XP_006886267.1 1e-60 241.1 Afrotheria GALK1 GO:0000166,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005524,GO:0005534,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006059,GO:0006066,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019388,GO:0019400,GO:0019402,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019751,GO:0019752,GO:0030246,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033499,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042866,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0048029,GO:0051186,GO:0051188,GO:0055086,GO:0061615,GO:0061620,GO:0061622,GO:0061623,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Mammalia 34Y0D@311790,38HFX@33154,3BGCU@33208,3CWGJ@33213,3JFIF@40674,4835A@7711,494MW@7742,COG0153@1,KOG0631@2759 NA|NA|NA G Galactokinase MAG.T2.42_01403 1142394.PSMK_04470 1.9e-72 279.3 Planctomycetes fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2IZCH@203682,COG1611@1,COG1611@2 NA|NA|NA NOU Possible lysine decarboxylase MAG.T2.42_01404 1142394.PSMK_11030 2.2e-127 463.0 Planctomycetes folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX24@203682,COG0285@1,COG0285@2 NA|NA|NA H folylpolyglutamate synthase MAG.T2.42_01406 857087.Metme_0413 1.4e-35 156.0 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T2.42_01407 1304885.AUEY01000096_gene2839 4.2e-192 678.3 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity MAG.T2.42_01408 1210884.HG799463_gene9416 6e-22 110.9 Planctomycetes ubiE2 Bacteria 2J382@203682,COG0500@1,COG1670@1,COG1670@2,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T2.42_01409 1356852.N008_09350 3.6e-07 63.2 Cytophagia htaA 3.4.21.72 ko:K01347 ko00000,ko01000,ko01002,ko02000,ko02044 1.B.12.3 Bacteria 47WC6@768503,4PNPJ@976,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein MAG.T2.42_01410 1123508.JH636439_gene672 3.6e-165 588.2 Planctomycetes guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IX43@203682,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth MAG.T2.42_01411 1142394.PSMK_14630 1.2e-104 386.7 Planctomycetes ko:K02669,ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX6Y@203682,COG2805@1,COG2805@2 NA|NA|NA NU twitching motility protein MAG.T2.42_01412 1142394.PSMK_14640 1.2e-84 320.9 Planctomycetes ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IZ37@203682,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase MAG.T2.42_01414 1123373.ATXI01000023_gene1785 1.8e-91 343.6 Thermodesulfobacteria Bacteria 2GHK9@200940,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T2.42_01416 1142394.PSMK_07250 1.4e-213 750.0 Planctomycetes polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2IXQR@203682,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity MAG.T2.42_01417 1142394.PSMK_32030 2.1e-44 186.8 Planctomycetes glmU 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXBV@203682,COG1207@1,COG1207@2 NA|NA|NA M Sugar nucleotidyl transferase MAG.T2.42_01420 1142394.PSMK_14530 1.2e-77 296.2 Planctomycetes mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 2IXSJ@203682,COG1077@1,COG1077@2 NA|NA|NA D COG1077 Actin-like ATPase involved in cell morphogenesis MAG.T2.42_01421 645512.GCWU000246_00108 1.2e-16 92.8 Synergistetes 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 3TBJQ@508458,COG0599@1,COG0599@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T2.42_01422 321332.CYB_1925 3.5e-34 151.8 Synechococcus ygaP GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016740,GO:0016782,GO:0016783,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 1G56U@1117,1H0R1@1129,COG0607@1,COG0607@2 NA|NA|NA P Protein of unknown function (DUF2892) MAG.T2.42_01423 483219.LILAB_00205 5.2e-23 115.2 Deltaproteobacteria ko:K03088 ko00000,ko03021 Bacteria 1MX7T@1224,2WRU7@28221,42W7K@68525,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase MAG.T2.42_01424 314230.DSM3645_17425 1.3e-147 530.4 Planctomycetes shc 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IXWT@203682,COG1657@1,COG1657@2 NA|NA|NA I COG1657 Squalene cyclase MAG.T2.42_01425 330214.NIDE0322 7.4e-76 291.2 Bacteria GO:0008150,GO:0040007 Bacteria COG4398@1,COG4398@2 NA|NA|NA E FIST C domain MAG.T2.42_01426 1536773.R70331_16820 9.8e-94 350.5 Paenibacillaceae Bacteria 1V300@1239,26TBI@186822,4HERM@91061,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase MAG.T2.42_01428 1210884.HG799465_gene11757 3.8e-109 401.7 Planctomycetes 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IY0I@203682,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T2.42_01429 756272.Plabr_3824 3.1e-94 352.1 Planctomycetes fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 iUTI89_1310.UTI89_C4836,ic_1306.c5329 Bacteria 2IWT3@203682,COG0158@1,COG0158@2 NA|NA|NA G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 MAG.T2.42_01431 661478.OP10G_1650 3.1e-202 711.4 Bacteria prpD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 R04424 RC01152 ko00000,ko00001,ko01000 Bacteria COG2079@1,COG2079@2 NA|NA|NA S 2-methylcitrate dehydratase activity MAG.T2.42_01432 1038859.AXAU01000005_gene5140 2.2e-17 95.9 Alphaproteobacteria ko:K06893 ko00000 Bacteria 1N487@1224,2UDWM@28211,COG3631@1,COG3631@2 NA|NA|NA S SnoaL-like domain MAG.T2.42_01433 1077144.AGFF01000026_gene656 1.8e-10 74.3 Actinobacteria ko:K07052 ko00000 Bacteria 2GUQM@201174,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease family protein MAG.T2.42_01434 243274.THEMA_07045 5.9e-39 167.2 Thermotogae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GD15@200918,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly MAG.T2.42_01435 1142394.PSMK_14090 1.9e-29 135.6 Planctomycetes rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J01J@203682,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family MAG.T2.42_01436 1403819.BATR01000085_gene2458 2.5e-27 129.0 Verrucomicrobiae Bacteria 2IUX8@203494,46Z4H@74201,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein MAG.T2.42_01437 1142394.PSMK_03840 3.4e-99 368.6 Planctomycetes dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IY9S@203682,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria MAG.T2.42_01438 1157708.KB907470_gene208 4.7e-35 155.2 Comamonadaceae Bacteria 1RD2X@1224,2VQ4B@28216,4ADII@80864,COG1225@1,COG1225@2 NA|NA|NA O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T2.42_01439 1142394.PSMK_07740 1.8e-35 156.0 Planctomycetes cmk 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IZVC@203682,COG0204@1,COG0204@2 NA|NA|NA I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase MAG.T2.42_01440 1142394.PSMK_08540 5.1e-54 218.0 Planctomycetes cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25 ko:K00800,ko:K00945,ko:K03977 ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230 M00022,M00052 R00158,R00512,R01665,R03460 RC00002,RC00350 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IZ6S@203682,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily MAG.T2.42_01441 1346330.M472_13380 6.7e-13 81.6 Bacteroidetes 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 4PM6P@976,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T2.42_01442 2045.KR76_16300 5.7e-30 137.1 Propionibacteriales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IKN2@201174,4DR5S@85009,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein MAG.T2.42_01443 314230.DSM3645_28492 4.6e-55 221.5 Planctomycetes ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IYZ3@203682,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner MAG.T2.42_01444 42256.RradSPS_0734 6.1e-35 156.4 Rubrobacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJTZ@201174,4CPJ5@84995,COG0577@1,COG0577@2,COG4591@1,COG4591@2 NA|NA|NA V FtsX-like permease family MAG.T2.42_01445 1142394.PSMK_19170 3.1e-237 828.2 Planctomycetes uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2IWS1@203682,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage MAG.T2.42_01446 521674.Plim_0274 5.5e-22 110.9 Planctomycetes Bacteria 2E3NE@1,2J1C2@203682,33ESP@2 NA|NA|NA S Protein of unknown function (DUF1569) MAG.T2.42_01447 1142394.PSMK_08180 6.6e-27 127.1 Planctomycetes yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2J0EV@203682,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA MAG.T2.42_01449 1382356.JQMP01000003_gene2342 3.7e-88 332.0 Thermomicrobia sufS 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 27XIH@189775,2G5T3@200795,COG0520@1,COG0520@2 NA|NA|NA E Beta-eliminating lyase MAG.T2.42_01452 1304275.C41B8_16449 3.2e-62 245.4 Gammaproteobacteria 2.1.1.334 ko:K21310 ko00920,map00920 R11546 RC02653 ko00000,ko00001,ko01000 Bacteria 1MWU6@1224,1S2PS@1236,COG2020@1,COG2020@2 NA|NA|NA O methyltransferase activity MAG.T2.42_01453 671143.DAMO_2920 2.3e-19 102.4 Bacteria Bacteria 2DRSH@1,33CVS@2 NA|NA|NA MAG.T2.42_01455 1142394.PSMK_07370 3.8e-42 178.3 Planctomycetes ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IZ2E@203682,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB MAG.T2.42_01456 1142394.PSMK_28660 1.4e-89 336.7 Planctomycetes manC 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXAR@203682,COG0836@1,COG0836@2 NA|NA|NA M Mannose-1-phosphate guanylyltransferase MAG.T2.42_01458 1142394.PSMK_22880 9.9e-86 323.9 Planctomycetes nuoH 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IXH1@203682,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone MAG.T2.42_01459 987059.RBXJA2T_12022 2.8e-64 253.1 unclassified Burkholderiales MA20_16655 Bacteria 1KNTZ@119065,1NJNA@1224,2VPNT@28216,COG1075@1,COG1075@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T2.42_01460 44060.JODL01000044_gene3976 1.8e-13 82.4 Bacteria ko:K21886,ko:K21903 ko00000,ko03000 Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity MAG.T2.42_01461 1121406.JAEX01000010_gene1341 2e-40 172.2 Desulfovibrionales arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1MWYQ@1224,2MBFG@213115,2WNEC@28221,42RQI@68525,COG0394@1,COG0394@2 NA|NA|NA T PFAM Protein-tyrosine phosphatase, low molecular weight MAG.T2.42_01462 1121445.ATUZ01000011_gene559 1.8e-81 309.7 Desulfovibrionales arsM 2.1.1.137,2.1.1.79 ko:K00574,ko:K07755 ko00000,ko01000 Bacteria 1MVXN@1224,2MGE4@213115,2WJIF@28221,42PQM@68525,COG0500@1,COG2226@2 NA|NA|NA Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MAG.T2.42_01463 504728.K649_09200 3.4e-57 228.8 Bacteria ko:K08714 ko00000,ko02000 1.A.1.14 Bacteria 2Z7ZD@2,COG1226@1 NA|NA|NA P Ion transport protein MAG.T2.42_01466 1142394.PSMK_22770 5.1e-184 651.0 Planctomycetes nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 Bacteria 2IY30@203682,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate MAG.T2.42_01467 264462.Bd2053 1e-27 131.3 Bdellovibrionales tolB ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 1MV86@1224,2MSYI@213481,2WURE@28221,42Z17@68525,COG0265@1,COG0265@2,COG0823@1,COG0823@2,COG2234@1,COG2234@2 NA|NA|NA OU Component of the Tol biopolymer transport system MAG.T2.42_01468 930166.CD58_22145 2e-56 225.7 Gammaproteobacteria rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.28,5.4.99.29 ko:K06177 ko00000,ko01000,ko03009,ko03016 Bacteria 1MVJ5@1224,1RN4N@1236,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T2.42_01470 321327.CYA_0280 9.1e-27 129.0 Bacteria exbB2 ko:K03561,ko:K12287 ko00000,ko02000,ko02044 1.A.30.2.1 Bacteria COG5306@1,COG5306@2 NA|NA|NA MAG.T2.42_01471 1123508.JH636453_gene5805 5.4e-13 82.8 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IY8U@203682,COG3391@1,COG3391@2 NA|NA|NA M Integrin alpha (beta-propellor repeats). MAG.T2.42_01472 1452536.JARE01000013_gene1651 1.5e-43 183.3 Microbacteriaceae ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 2GKC5@201174,4FNHN@85023,COG0307@1,COG0307@2 NA|NA|NA H Lumazine binding domain MAG.T2.42_01475 1142394.PSMK_31900 4.5e-72 277.7 Planctomycetes groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2IXA7@203682,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T2.42_01476 1163409.UUA_00135 8.2e-42 176.8 Xanthomonadales vsr GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 ko:K07458 ko00000,ko01000,ko03400 iB21_1397.ECBD_1686,iECD_1391.ECBD_1686 Bacteria 1RH1C@1224,1S2V3@1236,1XAV6@135614,COG3727@1,COG3727@2 NA|NA|NA L DNA mismatch endonuclease Vsr MAG.T2.42_01479 1142394.PSMK_04810 8.8e-101 374.0 Planctomycetes Bacteria 2IWSI@203682,COG0612@1,COG0612@2 NA|NA|NA S Belongs to the peptidase M16 family MAG.T2.42_01480 1142394.PSMK_01260 3.1e-28 132.5 Planctomycetes recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 ko:K03474,ko:K03584 ko00750,ko01100,ko03440,map00750,map01100,map03440 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IZU9@203682,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination MAG.T2.42_01481 1267533.KB906733_gene3472 1.3e-91 345.1 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01485 1142394.PSMK_01390 1.6e-40 174.9 Planctomycetes Bacteria 2IXP0@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A MAG.T2.42_01486 1142394.PSMK_22890 8.7e-51 208.4 Planctomycetes 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2IY6X@203682,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family MAG.T2.42_01487 530564.Psta_0115 1.7e-51 210.7 Planctomycetes tpl Bacteria 2IWZD@203682,COG1774@1,COG1774@2 NA|NA|NA S signal peptidase-like protein MAG.T2.42_01488 1142394.PSMK_08160 1.3e-103 383.6 Planctomycetes der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2IWXY@203682,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis MAG.T2.42_01489 1142394.PSMK_15330 3.3e-136 491.9 Planctomycetes fumC 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX95@203682,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T2.42_01490 1254432.SCE1572_44265 4.9e-130 471.9 Myxococcales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 1MU4J@1224,2WKII@28221,2YU3K@29,42MTY@68525,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase MAG.T2.42_01492 1123242.JH636435_gene2795 4e-36 157.9 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J3CV@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.42_01494 1142394.PSMK_23620 1.1e-126 459.9 Planctomycetes ampS5 ko:K19689 ko00000,ko01000,ko01002 Bacteria 2IXZW@203682,COG2309@1,COG2309@2 NA|NA|NA E PFAM Thermophilic metalloprotease (M29) MAG.T2.42_01495 438753.AZC_2233 3.8e-19 102.1 Alphaproteobacteria 3.6.1.27 ko:K09824,ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1MZ81@1224,2UE4K@28211,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily MAG.T2.42_01498 502025.Hoch_6539 5.8e-26 126.3 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_01499 604331.AUHY01000001_gene1225 2.9e-56 225.3 Bacteria Bacteria COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase activity MAG.T2.42_01500 864702.OsccyDRAFT_2584 7e-160 571.6 Oscillatoriales phy 3.1.3.1,3.1.3.8,3.1.4.46 ko:K01077,ko:K01083,ko:K01113,ko:K01126,ko:K07093 ko00562,ko00564,ko00730,ko00790,ko01100,ko02020,map00562,map00564,map00730,map00790,map01100,map02020 M00126 R01030,R01470,R02135,R03371,R04620 RC00017,RC00078,RC00425 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1G00S@1117,1H7VZ@1150,COG2931@1,COG2931@2,COG3540@1,COG3540@2,COG4222@1,COG4222@2,COG4247@1,COG4247@2 NA|NA|NA Q protein conserved in bacteria MAG.T2.42_01501 1403819.BATR01000104_gene3634 6.3e-197 694.1 Verrucomicrobiae Bacteria 2IV9P@203494,46TNW@74201,COG1297@1,COG1297@2 NA|NA|NA S OPT oligopeptide transporter protein MAG.T2.42_01503 391625.PPSIR1_26006 1.1e-49 205.3 Myxococcales Bacteria 1MVZN@1224,2WYZN@28221,2Z10G@29,434NC@68525,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T2.42_01504 1385515.N791_00445 5.7e-52 211.1 Gammaproteobacteria Bacteria 1QU2M@1224,1SCHV@1236,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T2.42_01505 1449976.KALB_2768 8e-68 264.2 Pseudonocardiales speB 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJA6@201174,4DZH8@85010,COG0010@1,COG0010@2 NA|NA|NA E Arginase family MAG.T2.42_01507 1286631.X805_37700 6.4e-63 248.1 Bacteria Bacteria 2DUWA@1,33SPG@2 NA|NA|NA MAG.T2.42_01509 1123508.JH636440_gene2097 2.6e-27 130.2 Planctomycetes tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 2IZDP@203682,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine MAG.T2.42_01510 1142394.PSMK_05440 3.5e-102 379.0 Planctomycetes murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2158c Bacteria 2IWUT@203682,COG0769@1,COG0769@2 NA|NA|NA M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T2.42_01511 546271.Selsp_1823 6.4e-49 201.8 Negativicutes murF GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13,6.3.2.7 ko:K01928,ko:K01929,ko:K05362,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02786,R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,4H2VD@909932,COG0769@1,COG0769@2,COG0770@1,COG0770@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T2.42_01512 1142394.PSMK_24980 3.9e-101 375.2 Planctomycetes mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2IXU1@203682,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan MAG.T2.42_01513 196490.AUEZ01000099_gene4932 2.6e-19 101.7 Bradyrhizobiaceae crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1MZNH@1224,2UBUP@28211,3K68P@41294,COG0239@1,COG0239@2 NA|NA|NA D CrcB-like protein, Camphor Resistance (CrcB) MAG.T2.42_01514 583355.Caka_2271 1.2e-29 137.1 Bacteria Bacteria 2E0WS@1,32WDT@2 NA|NA|NA S Protein of unknown function (DUF3450) MAG.T2.42_01515 452637.Oter_2347 1.9e-44 187.2 Opitutae exbB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 3K7V1@414999,46VCM@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family MAG.T2.42_01516 1156937.MFUM_1010012 7.2e-26 123.6 unclassified Verrucomicrobia ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 37GRQ@326457,46W74@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR MAG.T2.42_01517 794903.OPIT5_30225 7.7e-12 77.8 Opitutae ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 3K9EK@414999,46WRI@74201,COG0810@1,COG0810@2 NA|NA|NA M Gram-negative bacterial TonB protein C-terminal MAG.T2.42_01518 1396141.BATP01000045_gene1809 1e-63 251.1 Verrucomicrobia Bacteria 2DVY4@1,33XNN@2,46VB3@74201 NA|NA|NA MAG.T2.42_01519 502025.Hoch_6441 2.4e-41 176.8 Deltaproteobacteria 4.2.1.129,4.2.1.137,5.4.99.17 ko:K06045,ko:K18115 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 1RDNW@1224,2WNQX@28221,42S7H@68525,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.42_01520 1142394.PSMK_25520 6.4e-98 364.8 Planctomycetes 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2IY60@203682,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family MAG.T2.42_01521 1142394.PSMK_24300 6.5e-75 288.5 Planctomycetes ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 2J39X@203682,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein MAG.T2.42_01522 1142394.PSMK_12400 1.4e-58 233.4 Planctomycetes pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2IXSF@203682,COG0284@1,COG0284@2 NA|NA|NA F Belongs to the OMP decarboxylase family. Type 2 subfamily MAG.T2.42_01523 1142394.PSMK_27230 7e-24 116.7 Planctomycetes ko:K03593 ko00000,ko03029,ko03036 Bacteria 2J1DX@203682,COG3536@1,COG3536@2 NA|NA|NA S Protein of unknown function (DUF971) MAG.T2.42_01526 1142394.PSMK_16220 3.5e-110 405.2 Planctomycetes patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IX5E@203682,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T2.42_01529 1142394.PSMK_16190 1.4e-32 146.0 Planctomycetes acpS 2.7.8.7 ko:K00997,ko:K06925 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2IZSD@203682,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein MAG.T2.42_01530 314230.DSM3645_19543 4.8e-26 125.9 Planctomycetes ctaA ko:K02259,ko:K03110 ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714 M00154,M00335 R07412 RC00769 ko00000,ko00001,ko00002,ko02044,ko03029 3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4 Bacteria 2IZCQ@203682,COG1612@1,COG1612@2 NA|NA|NA O protein required for cytochrome oxidase assembly MAG.T2.42_01531 497964.CfE428DRAFT_2237 4e-62 245.4 Verrucomicrobia ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 iJN746.PP_0110,iSB619.SA_RS05465,iSFxv_1172.SFxv_0410,iYO844.BSU12080 Bacteria 46SQE@74201,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group MAG.T2.42_01532 998674.ATTE01000001_gene3400 1.3e-32 147.5 Gammaproteobacteria Bacteria 1N82C@1224,1RQQI@1236,COG2128@1,COG2128@2 NA|NA|NA S Protein of unknown function (DUF3179) MAG.T2.42_01534 1183438.GKIL_2537 2.8e-45 189.9 Cyanobacteria Bacteria 1G1UY@1117,COG0457@1,COG0457@2 NA|NA|NA S Alternative locus ID MAG.T2.42_01535 755732.Fluta_1390 1.5e-08 67.4 Flavobacteriia 3.4.21.50 ko:K01337 ko00000,ko01000,ko01002 Bacteria 1I21K@117743,4NNHP@976,COG3291@1,COG3291@2,COG3405@1,COG3405@2 NA|NA|NA U Pkd domain containing protein MAG.T2.42_01536 1183438.GKIL_0707 1.4e-12 81.3 Bacteria Bacteria COG2706@1,COG2706@2 NA|NA|NA G 6-phosphogluconolactonase activity MAG.T2.42_01539 530564.Psta_4767 1.6e-107 396.4 Planctomycetes aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 2IY2Z@203682,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system MAG.T2.42_01542 1396141.BATP01000007_gene5607 1.3e-30 142.1 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process MAG.T2.42_01543 283942.IL0616 2.6e-136 492.3 Idiomarinaceae argH GO:0003674,GO:0003824,GO:0004042,GO:0004056,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K00619,ko:K01755,ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844,M00845 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iAF987.Gmet_0946 Bacteria 1MUTU@1224,1RMA3@1236,2QFCX@267893,COG0165@1,COG0165@2,COG1246@1,COG1246@2 NA|NA|NA E belongs to the lyase 1 family. Argininosuccinate lyase subfamily MAG.T2.42_01544 1127673.GLIP_3460 3.5e-15 87.0 Alteromonadaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1MV0Y@1224,1RMEC@1236,464YE@72275,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily MAG.T2.42_01547 1121013.P873_12305 1.7e-41 176.4 Xanthomonadales Bacteria 1MUUV@1224,1RMJU@1236,1X51Z@135614,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MAG.T2.42_01549 595460.RRSWK_03438 1.7e-13 85.9 Planctomycetes Bacteria 2IYVI@203682,COG2982@1,COG2982@2 NA|NA|NA M Protein involved in outer membrane biogenesis MAG.T2.42_01550 1444711.CCJF01000005_gene155 6.8e-105 387.5 Chlamydiae fas6 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2JGZ7@204428,COG1611@1,COG1611@2 NA|NA|NA S Possible lysine decarboxylase MAG.T2.42_01551 314345.SPV1_08221 3.9e-70 271.2 Proteobacteria folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY3N@1224,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase MAG.T2.42_01552 391625.PPSIR1_02641 3.6e-59 235.0 Proteobacteria Bacteria 1N8G3@1224,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T2.42_01553 765952.PUV_06410 5.8e-190 670.6 Bacteria glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria COG0423@1,COG0423@2 NA|NA|NA J glycyl-tRNA aminoacylation MAG.T2.42_01554 1123242.JH636435_gene2591 1.2e-134 486.9 Planctomycetes ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 2IXSU@203682,COG2317@1,COG2317@2 NA|NA|NA E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues MAG.T2.42_01556 926550.CLDAP_17400 1.2e-33 151.0 Chloroflexi GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 ko:K06990 ko00000,ko04812 Bacteria 2G835@200795,COG1355@1,COG1355@2 NA|NA|NA S Memo-like protein MAG.T2.42_01557 518766.Rmar_2367 6.1e-39 167.2 Bacteroidetes Order II. Incertae sedis dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1FJDS@1100069,4NNFF@976,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality MAG.T2.42_01558 926550.CLDAP_04870 1.5e-84 320.9 Chloroflexi Bacteria 2G62S@200795,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T2.42_01560 1192034.CAP_8072 6.9e-61 241.1 Myxococcales oppB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1MU8Z@1224,2X5XK@28221,2Z2YK@29,43AFB@68525,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component MAG.T2.42_01561 1408813.AYMG01000019_gene1785 1.4e-64 253.4 Sphingobacteriia aspG GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 ko:K01424,ko:K01444,ko:K13051 ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 1IQZS@117747,4NE3D@976,COG1446@1,COG1446@2 NA|NA|NA E PFAM peptidase T2 asparaginase 2 MAG.T2.42_01562 1210884.HG799464_gene10771 1.8e-07 63.9 Bacteria Bacteria COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif MAG.T2.42_01563 1499967.BAYZ01000171_gene5617 1.6e-88 333.6 unclassified Bacteria htrA GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2NNVS@2323,COG0265@1,COG0265@2 NA|NA|NA O smart pdz dhr glgf MAG.T2.42_01564 1142394.PSMK_11490 4e-07 62.8 Planctomycetes ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IXC8@203682,COG2165@1,COG2165@2 NA|NA|NA NU TIGRFAM prepilin-type N-terminal cleavage methylation domain MAG.T2.42_01565 1142394.PSMK_11490 3.7e-08 66.2 Planctomycetes ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IXC8@203682,COG2165@1,COG2165@2 NA|NA|NA NU TIGRFAM prepilin-type N-terminal cleavage methylation domain MAG.T2.42_01566 1469607.KK073768_gene1384 1.6e-34 153.3 Nostocales 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1G6CG@1117,1HUBP@1161,COG0500@1,COG0500@2,COG0546@1,COG0546@2 NA|NA|NA Q Nodulation protein S (NodS) MAG.T2.42_01567 1142394.PSMK_01700 1e-119 436.8 Planctomycetes ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IXY1@203682,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing MAG.T2.42_01568 644282.Deba_3182 1.1e-39 171.8 Deltaproteobacteria rsbU 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 1MXJQ@1224,2WIJ4@28221,42MFQ@68525,COG2208@1,COG2208@2,COG2770@1,COG2770@2 NA|NA|NA KT SMART protein phosphatase 2C domain protein MAG.T2.42_01570 1123377.AUIV01000005_gene1688 2e-44 186.8 Xanthomonadales baeS Bacteria 1RAKD@1224,1S33T@1236,1X3EC@135614,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T2.42_01571 1120950.KB892707_gene4565 2.5e-57 228.8 Actinobacteria narP Bacteria 2GKBX@201174,COG2197@1,COG2197@2 NA|NA|NA T response regulator, receiver MAG.T2.42_01572 1313421.JHBV01000043_gene3012 2.9e-142 511.9 Sphingobacteriia kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ2Y@117747,4NECS@976,COG3844@1,COG3844@2 NA|NA|NA E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively MAG.T2.42_01573 5786.XP_003292085.1 1.8e-129 469.2 Amoebozoa ACMSD GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 Eukaryota 3XBM6@554915,COG2159@1,KOG4245@2759 NA|NA|NA S Amidohydrolase MAG.T2.42_01574 351160.RCIX1279 3.1e-42 179.5 Methanomicrobia ko:K07133 ko00000 Archaea 2NBPS@224756,2XWHF@28890,COG1373@1,arCOG03167@2157 NA|NA|NA S AAA domain MAG.T2.42_01575 1048983.EL17_13545 6.6e-47 194.1 Cytophagia nbaC 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 Bacteria 47PIW@768503,4NFU2@976,COG0662@1,COG0662@2 NA|NA|NA G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate MAG.T2.42_01576 197221.22294708 2.2e-94 352.8 Cyanobacteria tlyC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 1G16U@1117,COG1253@1,COG1253@2 NA|NA|NA S PFAM CBS domain MAG.T2.42_01578 1333998.M2A_1415 2.3e-124 452.6 unclassified Alphaproteobacteria hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV2K@1224,2TSTH@28211,4BPJZ@82117,COG0124@1,COG0124@2 NA|NA|NA J Histidyl-tRNA synthetase MAG.T2.42_01580 292564.Cyagr_1751 8.3e-17 93.2 Cyanobium Bacteria 1GMPX@1117,22TPW@167375,2BSEC@1,32MGB@2 NA|NA|NA MAG.T2.42_01581 69042.WH5701_04270 1e-13 82.4 Cyanobacteria Bacteria 1GA8J@1117,2EHRH@1,33BH9@2 NA|NA|NA S Domain of unknown function (DUF4926) MAG.T2.42_01582 1123242.JH636435_gene1401 3.5e-08 64.7 Planctomycetes Bacteria 2EGJW@1,2J4FU@203682,33AC1@2 NA|NA|NA MAG.T2.42_01583 1123242.JH636435_gene1400 7.9e-239 833.2 Planctomycetes 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY9E@203682,COG1070@1,COG1070@2 NA|NA|NA G MutL protein MAG.T2.42_01584 63737.Npun_F6328 7.9e-32 143.3 Nostocales MA20_24580 Bacteria 1G0HA@1117,1HNTY@1161,COG0431@1,COG0431@2 NA|NA|NA S Flavodoxin-like fold MAG.T2.42_01585 1142394.PSMK_28940 1.4e-99 369.8 Planctomycetes prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2IWU3@203682,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA MAG.T2.42_01587 614083.AWQR01000056_gene3579 1.4e-29 136.3 Comamonadaceae Bacteria 1N0SN@1224,2VS8Y@28216,4AJM5@80864,COG3797@1,COG3797@2 NA|NA|NA S Protein of unknown function (DUF1697) MAG.T2.42_01588 1142394.PSMK_01400 3.2e-131 474.9 Planctomycetes purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2IYCG@203682,COG0150@1,COG0150@2 NA|NA|NA F PFAM AIR synthase related protein MAG.T2.42_01589 1142394.PSMK_22870 2.7e-113 415.2 Planctomycetes sucD GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iYO844.BSU16100 Bacteria 2IWYV@203682,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit MAG.T2.42_01590 530564.Psta_1360 4.2e-53 217.2 Planctomycetes 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IX8J@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.42_01591 595460.RRSWK_05221 4.4e-16 91.3 Planctomycetes exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2J0IN@203682,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein MAG.T2.42_01592 521674.Plim_0746 5.8e-35 154.5 Planctomycetes exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IZ3U@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA TolQ ExbB proton channel MAG.T2.42_01593 309807.SRU_1584 2.6e-07 64.7 Bacteroidetes Order II. Incertae sedis bamD ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria 1FJ24@1100069,4NE4W@976,COG0457@1,COG0457@2,COG1729@1,COG1729@2,COG4105@1,COG4105@2 NA|NA|NA S Anaphase-promoting complex, cyclosome, subunit 3 MAG.T2.42_01594 886293.Sinac_1394 2e-29 138.3 Planctomycetes Bacteria 2IZRJ@203682,COG4219@1,COG4219@2 NA|NA|NA KT Antirepressor regulating drug resistance MAG.T2.42_01595 886293.Sinac_3274 1.1e-19 103.2 Planctomycetes Bacteria 2J0D9@203682,COG3682@1,COG3682@2 NA|NA|NA K penicillinase repressor MAG.T2.42_01596 1121382.JQKG01000020_gene1204 1.4e-21 109.4 Bacteria 2.3.1.255 ko:K20791 ko00000,ko01000,ko03036 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.42_01599 1210884.HG799464_gene10779 1.2e-19 103.2 Planctomycetes Bacteria 2A52F@1,2IZD2@203682,30TQU@2 NA|NA|NA MAG.T2.42_01600 1267533.KB906733_gene3472 1.9e-97 364.0 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01601 314230.DSM3645_11631 6.4e-44 184.1 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_01602 84531.JMTZ01000001_gene2271 1.3e-15 91.3 Bacteria 3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3 ko:K01337,ko:K01387,ko:K05994,ko:K08604,ko:K14645,ko:K20276 ko02024,ko05110,ko05111,map02024,map05110,map05111 ko00000,ko00001,ko01000,ko01002,ko02042,ko03110 Bacteria COG3291@1,COG3291@2,COG3420@1,COG3420@2,COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_01604 452637.Oter_1515 1.2e-108 400.2 Verrucomicrobia acrA ko:K02005 ko00000 Bacteria 46UZZ@74201,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like MAG.T2.42_01605 452637.Oter_1514 1.7e-96 359.0 Opitutae tptC ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 3K9FX@414999,46YZ8@74201,COG1136@1,COG1136@2 NA|NA|NA P PFAM ABC transporter related MAG.T2.42_01606 452637.Oter_1513 4e-127 461.5 Bacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity MAG.T2.42_01607 1396418.BATQ01000078_gene594 1.7e-149 535.8 Verrucomicrobiae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVBP@203494,46UQN@74201,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T2.42_01608 1458427.BAWN01000013_gene920 2.3e-110 406.0 Betaproteobacteria ko:K07133 ko00000 Bacteria 1R3UA@1224,2VQ1T@28216,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T2.42_01610 1129794.C427_5319 1.5e-23 117.1 Alteromonadaceae mshQ 4.2.2.3 ko:K01729,ko:K03048,ko:K07448,ko:K12287 ko00051,ko00230,ko00240,ko01100,ko03020,map00051,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443,R03706 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko02044,ko02048,ko03021,ko03400 Bacteria 1NGRY@1224,1T22S@1236,467Z0@72275,COG3343@1,COG3343@2,COG3420@1,COG3420@2 NA|NA|NA P regulator of chromosome condensation, RCC1 MAG.T2.42_01611 478801.Ksed_18670 4e-54 218.8 Bacteria wcfH Bacteria COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase MAG.T2.42_01612 391625.PPSIR1_05583 7.1e-27 129.8 Myxococcales 3.1.3.64 ko:K07004,ko:K21302 ko00562,ko01100,ko05152,map00562,map01100,map05152 ko00000,ko00001,ko01000 Bacteria 1Q6DC@1224,2WYJ7@28221,2Z34H@29,432XR@68525,COG3227@1,COG3227@2 NA|NA|NA E Zinc metalloprotease (Elastase) MAG.T2.42_01613 243090.RB621 1.4e-35 156.4 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2IZ8A@203682,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_01614 41875.XP_007511760.1 1.5e-09 70.1 Chlorophyta Viridiplantae 290BR@1,2R76S@2759,34IUP@3041,37XR2@33090 NA|NA|NA S Concanavalin A-like lectin/glucanases superfamily MAG.T2.42_01615 595460.RRSWK_04778 1.3e-115 424.9 Planctomycetes Bacteria 2IXZY@203682,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA T COG0515 Serine threonine protein MAG.T2.42_01616 1121936.AUHI01000004_gene1618 4e-22 110.5 Bacilli rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome MAG.T2.42_01617 521674.Plim_0380 1.5e-189 669.8 Planctomycetes pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2IWXZ@203682,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction MAG.T2.42_01618 381764.Fnod_1732 1.2e-12 79.0 Thermotogae cspA ko:K03704 ko00000,ko03000 Bacteria 2GDFN@200918,COG1278@1,COG1278@2 NA|NA|NA K PFAM Cold-shock protein, DNA-binding MAG.T2.42_01619 1142394.PSMK_05310 2.9e-53 215.7 Bacteria Bacteria COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T2.42_01621 446462.Amir_5433 1.5e-12 79.7 Pseudonocardiales Bacteria 2E37T@1,2GQH5@201174,32Y7G@2,4E6DF@85010 NA|NA|NA S Protein of unknown function (DUF2752) MAG.T2.42_01622 879243.Poras_0441 7.7e-11 73.9 Porphyromonadaceae Bacteria 231X5@171551,2G2JT@200643,4PNK2@976,COG4640@1,COG4640@2 NA|NA|NA S Interferon-induced transmembrane protein MAG.T2.42_01626 1142394.PSMK_15370 1.1e-156 559.7 Planctomycetes clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2IXDS@203682,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP MAG.T2.42_01628 1142394.PSMK_15390 1.2e-62 247.7 Planctomycetes tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 2IXGD@203682,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase MAG.T2.42_01629 1123371.ATXH01000013_gene1529 1e-80 307.0 Thermodesulfobacteria purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GH07@200940,COG0152@1,COG0152@2 NA|NA|NA F SAICAR synthetase MAG.T2.42_01630 1392489.JPOL01000002_gene2301 4.9e-28 131.3 Flavobacteriia Bacteria 1I20I@117743,4NP71@976,COG2930@1,COG2930@2 NA|NA|NA S Pfam Family of MAG.T2.42_01631 1142394.PSMK_21970 2.3e-90 339.7 Planctomycetes Bacteria 2IXI6@203682,COG3693@1,COG3693@2 NA|NA|NA G PFAM glycoside hydrolase, family 10 MAG.T2.42_01632 1142394.PSMK_23320 1.3e-266 926.4 Planctomycetes mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 GT51 Bacteria 2IWV4@203682,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site MAG.T2.42_01633 497964.CfE428DRAFT_1907 1.2e-48 200.7 Bacteria 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria COG2365@1,COG2365@2 NA|NA|NA T protein tyrosine phosphatase activity MAG.T2.42_01634 1123377.AUIV01000014_gene490 1.4e-44 187.2 Xanthomonadales 2.7.11.1 ko:K14949 ko05152,map05152 ko00000,ko00001,ko01000,ko01001 Bacteria 1MVEU@1224,1S0IU@1236,1X4DU@135614,COG0515@1,COG0515@2,COG5010@1,COG5010@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.42_01635 502025.Hoch_1402 3e-12 79.0 Proteobacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1N3BR@1224,COG1595@1,COG1595@2 NA|NA|NA K rna polymerase sigma factor MAG.T2.42_01637 1210884.HG799462_gene8941 1.2e-143 516.5 Planctomycetes glnN 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2IXF6@203682,COG3968@1,COG3968@2 NA|NA|NA S Glutamine synthetase type III MAG.T2.42_01638 314230.DSM3645_27331 3.5e-69 272.3 Planctomycetes gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria 2IX4B@203682,COG1450@1,COG1450@2 NA|NA|NA NU general secretion pathway protein D MAG.T2.42_01641 243090.RB13224 1.2e-147 530.0 Planctomycetes Bacteria 2IYQV@203682,COG0702@1,COG0702@2 NA|NA|NA GM PFAM NAD-dependent epimerase dehydratase MAG.T2.42_01642 313628.LNTAR_02467 8.3e-55 221.9 Bacteria Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion MAG.T2.42_01644 521674.Plim_1885 1.1e-134 486.9 Planctomycetes Bacteria 2IXY4@203682,COG1574@1,COG1574@2 NA|NA|NA Q PFAM amidohydrolase MAG.T2.42_01646 231434.JQJH01000001_gene1777 0.0 1082.4 Beijerinckiaceae 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2TTXG@28211,3NC5Q@45404,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T2.42_01647 1210884.HG799468_gene13574 1.6e-25 123.6 Bacteria wspE 2.7.13.3 ko:K03407,ko:K13490 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00509 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria COG2198@1,COG2198@2 NA|NA|NA T Histidine kinase MAG.T2.42_01648 1210884.HG799468_gene13575 7.1e-176 624.8 Planctomycetes cheA 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 2IWWG@203682,COG0643@1,COG0643@2 NA|NA|NA T Signal transducing histidine kinase, homodimeric MAG.T2.42_01649 1123242.JH636434_gene5115 2.3e-15 89.0 Planctomycetes cheW ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 2J3QK@203682,COG0835@1,COG0835@2 NA|NA|NA NT Two component signalling adaptor domain MAG.T2.42_01650 1210884.HG799468_gene13577 1.1e-59 238.4 Planctomycetes ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 2J2K6@203682,COG0840@1,COG0840@2 NA|NA|NA NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). MAG.T2.42_01651 1210884.HG799468_gene13578 1.2e-82 313.5 Planctomycetes 3.1.1.61,3.5.1.44 ko:K03412,ko:K03413 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 2IX6F@203682,COG2201@1,COG2201@2 NA|NA|NA NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR MAG.T2.42_01652 1191299.AJYX01000065_gene3729 4.3e-41 175.3 Vibrionales cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 Bacteria 1MU6W@1224,1RMFK@1236,1XSQ2@135623,COG1352@1,COG1352@2 NA|NA|NA NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP MAG.T2.42_01653 105559.Nwat_0836 8.2e-58 231.5 Proteobacteria ko:K07267 ko00000,ko02000 1.B.19.1 Bacteria 1QIBX@1224,COG3659@1,COG3659@2 NA|NA|NA M PFAM Carbohydrate-selective porin OprB MAG.T2.42_01654 1403819.BATR01000009_gene302 2.9e-196 691.4 Verrucomicrobiae 3.1.6.12 ko:K01135 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVET@203494,46TNU@74201,COG3119@1,COG3119@2 NA|NA|NA P Type I phosphodiesterase / nucleotide pyrophosphatase MAG.T2.42_01656 1089550.ATTH01000001_gene449 1.6e-13 83.6 Bacteroidetes cspBA ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria 4NTWX@976,COG1404@1,COG1404@2,COG4412@1,COG4412@2 NA|NA|NA O Peptidase, S8 S53 family MAG.T2.42_01659 382464.ABSI01000011_gene2613 1.3e-65 256.5 Verrucomicrobiae wcoQ ko:K09166 ko00000 Bacteria 2IWKA@203494,46WXC@74201,COG3361@1,COG3361@2 NA|NA|NA S Uncharacterized conserved protein (COG2071) MAG.T2.42_01661 1144319.PMI16_02675 1.5e-53 215.7 Proteobacteria ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 ko:K03829 ko00000,ko01000 Bacteria 1QUHE@1224,COG0454@1,COG0454@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases MAG.T2.42_01662 316058.RPB_0714 4.8e-23 115.5 Bradyrhizobiaceae andR Bacteria 1R81X@1224,2U1RK@28211,3JTU6@41294,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator, AraC family MAG.T2.42_01663 179408.Osc7112_0861 4.7e-34 152.9 Oscillatoriales Bacteria 1G5KY@1117,1HCKH@1150,COG2931@1,COG2931@2 NA|NA|NA Q COG2931 RTX toxins and related Ca2 -binding MAG.T2.42_01664 1142394.PSMK_20170 1.1e-39 170.6 Bacteria ko:K09384 ko00000 Bacteria COG1075@1,COG1075@2 NA|NA|NA KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T2.42_01665 314285.KT71_17596 4.3e-85 322.0 unclassified Gammaproteobacteria Bacteria 1J8UM@118884,1N90Y@1224,1TJ8Y@1236,COG4782@1,COG4782@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF900) MAG.T2.42_01666 583355.Caka_2641 6e-27 129.0 Bacteria Bacteria 2C6BE@1,32XBJ@2 NA|NA|NA MAG.T2.42_01667 314285.KT71_09307 8.8e-08 63.5 Bacteria Bacteria 2E2JB@1,32XNT@2 NA|NA|NA MAG.T2.42_01672 518766.Rmar_1508 2.6e-20 105.9 Bacteroidetes Order II. Incertae sedis maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1FJAU@1100069,4NNXV@976,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T2.42_01674 1142394.PSMK_30040 1.5e-45 190.3 Planctomycetes lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 Bacteria 2IXYX@203682,COG1663@1,COG1663@2 NA|NA|NA F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) MAG.T2.42_01675 1142394.PSMK_02310 5.9e-126 458.0 Planctomycetes hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272,ko:K21345 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_0922 Bacteria 2IY6V@203682,COG0615@1,COG0615@2,COG2870@1,COG2870@2 NA|NA|NA H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose MAG.T2.42_01676 247490.KSU1_B0124 6.8e-20 104.0 Planctomycetes ko:K03530,ko:K05788 ko00000,ko03032,ko03036,ko03400 Bacteria 2J01P@203682,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family MAG.T2.42_01678 1142394.PSMK_13120 3.6e-78 298.5 Planctomycetes dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2IXJT@203682,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T2.42_01679 1142394.PSMK_24820 5.9e-27 127.9 Planctomycetes adsA ko:K03088 ko00000,ko03021 Bacteria 2J17G@203682,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_01682 1142394.PSMK_07270 1.9e-67 263.1 Planctomycetes oppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021 Bacteria 2IYF0@203682,COG1173@1,COG1173@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component MAG.T2.42_01683 396588.Tgr7_0947 8.8e-92 344.7 Chromatiales oppA_5 ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 1MUZH@1224,1SZ84@1236,1WXUW@135613,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle MAG.T2.42_01684 1142394.PSMK_25080 4.8e-88 332.0 Planctomycetes oppB ko:K02033,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 2IYGR@203682,COG0601@1,COG0601@2 NA|NA|NA P transport systems MAG.T2.42_01685 105559.Nwat_0316 7.2e-70 271.6 Chromatiales appC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MU26@1224,1RND6@1236,1X0EV@135613,COG1173@1,COG1173@2 NA|NA|NA P PFAM binding-protein-dependent transport systems inner membrane component MAG.T2.42_01686 1123504.JQKD01000002_gene4001 7.6e-88 330.9 Comamonadaceae oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1R4KB@1224,2W0NK@28216,4AC21@80864,COG0444@1,COG0444@2 NA|NA|NA P TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit MAG.T2.42_01687 391625.PPSIR1_05583 3e-27 131.0 Myxococcales 3.1.3.64 ko:K07004,ko:K21302 ko00562,ko01100,ko05152,map00562,map01100,map05152 ko00000,ko00001,ko01000 Bacteria 1Q6DC@1224,2WYJ7@28221,2Z34H@29,432XR@68525,COG3227@1,COG3227@2 NA|NA|NA E Zinc metalloprotease (Elastase) MAG.T2.42_01689 330214.NIDE0244 6.9e-63 247.7 Nitrospirae queE 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 iAF987.Gmet_1658 Bacteria 3J0M2@40117,COG0602@1,COG0602@2 NA|NA|NA H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds MAG.T2.42_01691 1142394.PSMK_01820 1.6e-56 226.5 Planctomycetes rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2IYUS@203682,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T2.42_01692 706434.HMPREF9429_01216 2.1e-13 82.0 Negativicutes gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,4H5K1@909932,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T2.42_01693 324602.Caur_1712 1.2e-139 503.4 Chloroflexia gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2G5T0@200795,375CN@32061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) MAG.T2.42_01694 1121091.AUMP01000003_gene2532 2.7e-38 166.0 Bacilli glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKW@1239,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase MAG.T2.42_01697 1142394.PSMK_17540 5.3e-107 395.6 Planctomycetes yqfF ko:K07037 ko00000 Bacteria 2IYP7@203682,COG1480@1,COG1480@2 NA|NA|NA S PFAM Metal-dependent phosphohydrolase, HD MAG.T2.42_01698 1142394.PSMK_14600 2e-60 239.6 Planctomycetes mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IY33@203682,COG1194@1,COG1194@2 NA|NA|NA L COG1194 A G-specific DNA glycosylase MAG.T2.42_01699 1217718.ALOU01000037_gene2059 8.5e-24 116.3 Burkholderiaceae nlpD_1 3.4.24.75 ko:K08259,ko:K21472 ko00000,ko01000,ko01002,ko01011 Bacteria 1KGYV@119060,1MVTF@1224,2VKR8@28216,COG0739@1,COG0739@2 NA|NA|NA M Peptidase M23 MAG.T2.42_01700 523791.Kkor_1325 1.6e-08 67.0 Bacteria Bacteria COG4313@1,COG4313@2 NA|NA|NA MAG.T2.42_01701 68260.JOAY01000023_gene3054 9.1e-07 60.5 Actinobacteria Bacteria 2GQK5@201174,COG2608@1,COG2608@2 NA|NA|NA P PFAM Heavy metal transport detoxification protein MAG.T2.42_01703 316067.Geob_0264 2.5e-20 107.1 Deltaproteobacteria rsbP 3.1.3.3 ko:K02660,ko:K07315,ko:K17763 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko01000,ko02035,ko02044,ko03021 Bacteria 1RCHY@1224,2WMR7@28221,42R1G@68525,COG2202@1,COG2202@2,COG2208@1,COG2208@2 NA|NA|NA KT SMART protein phosphatase 2C domain protein MAG.T2.42_01704 1142394.PSMK_28390 2.9e-70 272.7 Planctomycetes ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iLJ478.TM1828,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 Bacteria 2IX5J@203682,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate MAG.T2.42_01706 102129.Lepto7375DRAFT_0845 9.4e-17 94.7 Bacteria Bacteria COG1572@1,COG1572@2,COG3209@1,COG3209@2 NA|NA|NA NU bacterial-type flagellum-dependent cell motility MAG.T2.42_01707 1121904.ARBP01000010_gene2266 4e-63 248.1 Cytophagia 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 47KCT@768503,4NF20@976,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T2.42_01709 622312.ROSEINA2194_00359 1.1e-21 112.5 Clostridia gldG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TT1J@1239,24BC2@186801,COG1277@1,COG1277@2,COG3225@1,COG3225@2 NA|NA|NA N -transport system MAG.T2.42_01710 1142394.PSMK_13820 2.6e-63 249.2 Planctomycetes gldA 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 Bacteria 2IX20@203682,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T2.42_01711 1142394.PSMK_22020 7.4e-98 364.8 Planctomycetes Bacteria 2IYBJ@203682,COG0784@1,COG0784@2,COG2203@1,COG2203@2 NA|NA|NA T response regulator receiver MAG.T2.42_01712 243090.RB12236 1.5e-07 63.9 Planctomycetes Bacteria 2J3SZ@203682,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain MAG.T2.42_01714 102125.Xen7305DRAFT_00025450 1.5e-64 254.2 Bacteria Bacteria COG1225@1,COG1225@2 NA|NA|NA O peroxiredoxin activity MAG.T2.42_01715 1392490.JHZX01000001_gene628 4.7e-51 209.5 Flavobacteriia Bacteria 1I1YW@117743,4PKTY@976,COG3291@1,COG3291@2 NA|NA|NA S ASPIC and UnbV MAG.T2.42_01717 309807.SRU_1823 7.5e-32 144.1 Bacteroidetes Order II. Incertae sedis Bacteria 1FK5W@1100069,4NQPD@976,COG1510@1,COG1510@2 NA|NA|NA K Belongs to the GbsR family MAG.T2.42_01718 391625.PPSIR1_07912 3e-29 137.5 Myxococcales ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1R5H7@1224,2WYZ0@28221,2Z0YZ@29,434MI@68525,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T2.42_01719 1142394.PSMK_02980 4.3e-120 438.3 Planctomycetes purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 Bacteria 2IX58@203682,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family MAG.T2.42_01720 344747.PM8797T_05890 3.7e-122 444.9 Planctomycetes ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2IXPP@203682,COG0686@1,COG0686@2 NA|NA|NA C Belongs to the AlaDH PNT family MAG.T2.42_01722 237368.SCABRO_02752 4.7e-97 361.3 Planctomycetes trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 2IX3E@203682,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family MAG.T2.42_01723 1123242.JH636436_gene287 4.8e-26 124.0 Planctomycetes rbpA Bacteria 2J0SR@203682,COG0724@1,COG0724@2 NA|NA|NA S RNA recognition motif MAG.T2.42_01724 521011.Mpal_1686 2.9e-64 253.4 Methanomicrobia Archaea 2N9BI@224756,2XVJN@28890,COG1404@1,arCOG02545@1,arCOG02545@2157,arCOG06823@2157 NA|NA|NA O Subtilase family MAG.T2.42_01725 1133849.O3I_032185 1.2e-09 69.7 Nocardiaceae ko:K02030,ko:K14475 ko05143,map05143 M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 2GXM1@201174,4G4J0@85025,COG5513@1,COG5513@2 NA|NA|NA S Chagasin family peptidase inhibitor I42 MAG.T2.42_01726 1267533.KB906733_gene3472 5.6e-61 243.0 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_01727 314230.DSM3645_11631 3.3e-35 155.2 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_01728 381666.H16_A3358 5.7e-136 491.9 Burkholderiaceae Bacteria 1K3DC@119060,1MX1Z@1224,2VKEC@28216,COG5164@1,COG5164@2 NA|NA|NA K regulation of DNA-templated transcription, elongation MAG.T2.42_01732 1128421.JAGA01000003_gene3134 3.2e-58 233.0 unclassified Bacteria 3.4.21.62 ko:K01342,ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2NP8X@2323,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T2.42_01733 575540.Isop_0101 9.1e-135 486.9 Planctomycetes metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXCJ@203682,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme MAG.T2.42_01734 243090.RB9985 1e-22 113.6 Planctomycetes Bacteria 28JE3@1,2J0PD@203682,2Z98B@2 NA|NA|NA MAG.T2.42_01735 1173024.KI912149_gene6446 9.9e-283 979.5 Stigonemataceae clpB GO:0003674,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0042802,GO:0043170,GO:0044238,GO:0071704,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1G04Z@1117,1JHRT@1189,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein MAG.T2.42_01736 1234364.AMSF01000013_gene639 5.7e-13 80.1 Gammaproteobacteria Bacteria 1P63I@1224,1SVPU@1236,295WS@1,2ZT7P@2 NA|NA|NA MAG.T2.42_01737 502025.Hoch_6539 4.4e-55 223.4 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_01738 448385.sce2508 4.5e-07 60.8 Myxococcales nhaS4 Bacteria 1MVGV@1224,2WQ9K@28221,2YXTM@29,42WJ6@68525,COG0475@1,COG0475@2,COG0589@1,COG0589@2 NA|NA|NA PT Sodium/hydrogen exchanger family MAG.T2.42_01740 1142394.PSMK_18920 6e-200 704.1 Planctomycetes tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2J56J@203682,COG0021@1,COG0021@2 NA|NA|NA H Transketolase, pyrimidine binding domain MAG.T2.42_01742 287986.DV20_17035 9.1e-16 90.5 Pseudonocardiales ko:K03088 ko00000,ko03021 Bacteria 2GJMX@201174,4E3X3@85010,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.42_01745 743721.Psesu_2213 4e-39 169.5 Xanthomonadales yxaH ko:K07148 ko00000 Bacteria 1MWHW@1224,1RQ08@1236,1X54V@135614,COG2311@1,COG2311@2 NA|NA|NA S membrane MAG.T2.42_01746 861299.J421_2552 6.9e-31 141.0 Gemmatimonadetes gph1 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1ZTK9@142182,COG0546@1,COG0546@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase MAG.T2.42_01747 1142394.PSMK_22310 1.3e-128 466.5 Planctomycetes sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXQU@203682,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit MAG.T2.42_01748 1142394.PSMK_16260 8.5e-38 164.1 Planctomycetes infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2IZ68@203682,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins MAG.T2.42_01749 378806.STAUR_4418 9.2e-63 248.4 Myxococcales ytfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 iAPECO1_1312.APECO1_2162,iECH74115_1262.ECH74115_5749,iECOK1_1307.ECOK1_4745,iECSF_1327.ECSF_4119,iLF82_1304.LF82_3716,iUTI89_1310.UTI89_C4834,ic_1306.c5327 Bacteria 1MUM6@1224,2WXP4@28221,2YWA2@29,432WP@68525,COG1172@1,COG1172@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family MAG.T2.42_01750 1246448.ANAZ01000035_gene165 4.9e-115 421.8 Streptosporangiales ytfR 3.6.3.17 ko:K02056 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 iECED1_1282.ECED1_5085 Bacteria 2GJ3F@201174,4EFPT@85012,COG1129@1,COG1129@2 NA|NA|NA G ATPases associated with a variety of cellular activities MAG.T2.42_01751 1122194.AUHU01000003_gene2268 5.7e-20 103.6 Gammaproteobacteria cI Bacteria 1P0VP@1224,1SSAM@1236,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain MAG.T2.42_01753 215803.DB30_6962 1.6e-108 399.4 Myxococcales ytfQ GO:0003674,GO:0005215,GO:0005488,GO:0005534,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015749,GO:0015757,GO:0016020,GO:0016021,GO:0022857,GO:0030246,GO:0030288,GO:0030313,GO:0031224,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0044425,GO:0044464,GO:0048029,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K02058 M00221 ko00000,ko00002,ko02000 3.A.1.2 iECH74115_1262.ECH74115_5745,iECSP_1301.ECSP_5328,iECs_1301.ECs5205,iG2583_1286.G2583_5057,iSSON_1240.SSON_4409,iZ_1308.Z5838 Bacteria 1MXJS@1224,2X6G0@28221,2YX15@29,42W3I@68525,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein-like domain MAG.T2.42_01754 768671.ThimaDRAFT_0223 8.7e-51 207.6 Gammaproteobacteria flgK ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZXB@1224,1RN1W@1236,COG4786@1,COG4786@2 NA|NA|NA N Protein of unknown function (DUF2950) MAG.T2.42_01755 1382359.JIAL01000001_gene104 2.2e-19 103.6 Acidobacteriia Bacteria 2JN3R@204432,3Y7SB@57723,COG3064@1,COG3064@2 NA|NA|NA M Protein of unknown function (DUF3300) MAG.T2.42_01756 82654.Pse7367_1414 3.7e-28 133.3 Oscillatoriales Bacteria 1G45J@1117,1H8ZF@1150,COG0739@1,COG0739@2 NA|NA|NA M PFAM peptidase MAG.T2.42_01757 420324.KI912031_gene2695 2.3e-102 379.4 Methylobacteriaceae ko:K03294 ko00000 2.A.3.2 Bacteria 1JR4Z@119045,1MXNJ@1224,2TRNX@28211,COG0531@1,COG0531@2 NA|NA|NA E PFAM amino acid permease-associated region MAG.T2.42_01758 575540.Isop_0689 2.1e-29 135.2 Planctomycetes thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IXFR@203682,COG0013@1,COG0013@2,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) MAG.T2.42_01760 216594.MMAR_0366 5.6e-30 140.2 Mycobacteriaceae pknK_3 Bacteria 233DM@1762,2GIZ1@201174,COG0515@1,COG0515@2,COG3903@1,COG3903@2 NA|NA|NA K involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein MAG.T2.42_01763 1415166.NONO_c36410 1.1e-24 122.5 Nocardiaceae 2.7.11.1 ko:K08282,ko:K13419 ko00000,ko01000,ko01001 Bacteria 2GIZ1@201174,4FUTU@85025,COG0515@1,COG0515@2,COG3903@1,COG3903@2 NA|NA|NA K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation MAG.T2.42_01765 1120948.KB903218_gene1921 3.8e-07 62.4 Pseudonocardiales ko:K03088 ko00000,ko03021 Bacteria 2GM8T@201174,4DY2F@85010,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.42_01766 1206720.BAFQ01000297_gene6708 4e-50 207.2 Nocardiaceae pknK_3 Bacteria 2GIZ1@201174,4FUTU@85025,COG0515@1,COG0515@2,COG3903@1,COG3903@2 NA|NA|NA K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation MAG.T2.42_01769 391625.PPSIR1_00035 3.6e-10 70.5 Deltaproteobacteria ko:K07485 ko00000 Bacteria 1MV5J@1224,2WK5I@28221,42M93@68525,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 MAG.T2.42_01770 1121946.AUAX01000005_gene5510 3.4e-19 104.4 Micromonosporales ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 2GRWY@201174,4DMB3@85008,COG3401@1,COG3401@2,COG5563@1,COG5563@2 NA|NA|NA S FG-GAP repeat protein MAG.T2.42_01772 1396418.BATQ01000189_gene762 9.3e-111 407.1 Verrucomicrobia 2.7.7.49 ko:K00986 ko00000,ko01000 Bacteria 46TQ6@74201,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) MAG.T2.42_01774 886293.Sinac_0291 8.3e-138 499.2 Planctomycetes Bacteria 2IY61@203682,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T2.42_01776 1123242.JH636434_gene4482 2.4e-53 217.2 Bacteria gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria COG1450@1,COG1450@2 NA|NA|NA NU protein transport across the cell outer membrane MAG.T2.42_01777 262724.TT_P0211 6.6e-104 384.4 Deinococcus-Thermus ko:K07133 ko00000 Bacteria 1WJIW@1297,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T2.42_01779 1123242.JH636434_gene4606 4.2e-43 182.6 Planctomycetes ko:K06940,ko:K18475 ko00000,ko01000,ko02035 Bacteria 2IZGA@203682,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T2.42_01780 748658.KB907312_gene1650 1.8e-39 169.5 Chromatiales rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Bacteria 1MUK5@1224,1S27C@1236,1WWJX@135613,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions MAG.T2.42_01781 886293.Sinac_6119 1.9e-170 605.9 Planctomycetes accD5 Bacteria 2IY0Q@203682,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) MAG.T2.42_01782 1142394.PSMK_14630 8.5e-71 274.2 Planctomycetes ko:K02669,ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IX6Y@203682,COG2805@1,COG2805@2 NA|NA|NA NU twitching motility protein MAG.T2.42_01784 661478.OP10G_2391 4.7e-179 634.8 Bacteria 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria COG1409@1,COG1409@2,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase MAG.T2.42_01785 1142394.PSMK_18220 2.6e-150 539.3 Planctomycetes ko:K06158 ko00000,ko03012 Bacteria 2IX59@203682,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T2.42_01786 1396141.BATP01000003_gene4869 4.1e-41 175.6 Verrucomicrobiae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVXU@203494,46XHK@74201,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component MAG.T2.42_01787 1396141.BATP01000003_gene4868 5.9e-74 284.6 Verrucomicrobiae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVHQ@203494,46SHV@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T2.42_01789 869210.Marky_2115 7.9e-39 167.5 Deinococcus-Thermus yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 1WI9I@1297,COG1496@1,COG1496@2 NA|NA|NA S Belongs to the multicopper oxidase YfiH RL5 family MAG.T2.42_01790 1123242.JH636435_gene2795 1.5e-24 119.4 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J3CV@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.42_01796 700598.Niako_5561 1.3e-18 100.5 Bacteria 2.1.1.243 ko:K16215 ko00000,ko01000 Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase MAG.T2.42_01797 631362.Thi970DRAFT_02815 1.8e-12 82.0 Bacteria Bacteria 2EWXB@1,33Q8Q@2 NA|NA|NA MAG.T2.42_01798 118163.Ple7327_2167 7.3e-07 63.2 Bacteria Bacteria 2EWXB@1,33Q8Q@2 NA|NA|NA MAG.T2.42_01801 3075.A0A087SNF6 2.1e-53 215.3 Viridiplantae AGT2 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0008144,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0016020,GO:0019842,GO:0030170,GO:0031090,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050896,GO:0070279,GO:0097159,GO:0098588,GO:0098805,GO:1901363 2.6.1.40,2.6.1.44 ko:K00827 ko00250,ko00260,ko00270,ko00280,ko01100,ko01110,map00250,map00260,map00270,map00280,map01100,map01110 R00369,R00372,R02050,R10992 RC00006,RC00008,RC00018,RC00160 ko00000,ko00001,ko01000,ko01007 Viridiplantae 37NZZ@33090,COG0160@1,KOG1404@2759 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T2.42_01802 1396141.BATP01000059_gene2566 1.7e-164 585.9 Verrucomicrobia dht 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 46UZF@74201,COG0044@1,COG0044@2 NA|NA|NA F Amidohydrolase family MAG.T2.42_01803 1396141.BATP01000059_gene2560 6.5e-141 507.3 Verrucomicrobia preA GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0051536,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_2293 Bacteria 46V5R@74201,COG0167@1,COG0167@2 NA|NA|NA CF Dihydroorotate dehydrogenase MAG.T2.42_01804 251221.35213566 6.2e-22 114.0 Cyanobacteria 3.2.1.4 ko:K01179,ko:K20276 ko00500,ko01100,ko02024,map00500,map01100,map02024 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1G72X@1117,COG1404@1,COG1404@2,COG5549@1,COG5549@2 NA|NA|NA O cellulose binding MAG.T2.42_01805 1121403.AUCV01000030_gene2788 1.6e-08 67.4 Bacteria Bacteria COG4447@1,COG4447@2 NA|NA|NA S cellulose binding MAG.T2.42_01807 349741.Amuc_2127 3e-57 229.6 Bacteria ko:K07267 ko00000,ko02000 1.B.19.1 Bacteria COG3659@1,COG3659@2 NA|NA|NA M wide pore channel activity MAG.T2.42_01808 1217718.ALOU01000061_gene514 7.7e-22 110.9 Burkholderiaceae Bacteria 1KC6N@119060,1RFGB@1224,2DM04@1,2VYTJ@28216,3139Z@2 NA|NA|NA S Ion channel MAG.T2.42_01809 314230.DSM3645_02138 6e-105 387.9 Planctomycetes dadA 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 2IX78@203682,COG0665@1,COG0665@2 NA|NA|NA C FAD dependent oxidoreductase MAG.T2.42_01810 1159870.KB907784_gene1916 6.6e-102 377.5 Alcaligenaceae GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 ko:K01777,ko:K12658 ko00330,ko01100,map00330,map01100 R01255,R03296 RC00479 ko00000,ko00001,ko01000 Bacteria 1NVF9@1224,2VHHY@28216,3T26R@506,COG3938@1,COG3938@2 NA|NA|NA E Proline racemase MAG.T2.42_01811 314230.DSM3645_02128 3e-93 348.6 Planctomycetes dapA2 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY4I@203682,COG0329@1,COG0329@2 NA|NA|NA EM Belongs to the DapA family MAG.T2.42_01812 1207063.P24_15836 1e-96 361.3 Rhodospirillales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MY63@1224,2JRJ2@204441,2U1SX@28211,COG3225@1,COG3225@2 NA|NA|NA N ABC-type uncharacterized transport system MAG.T2.42_01813 1384056.N787_00035 6.9e-75 287.3 Xanthomonadales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1NZZ9@1224,1RP6C@1236,1X35D@135614,COG1277@1,COG1277@2 NA|NA|NA S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component MAG.T2.42_01814 794903.OPIT5_19565 8.1e-71 273.9 Opitutae 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 Bacteria 3K7BH@414999,46UCI@74201,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter related MAG.T2.42_01816 448385.sce2344 5.4e-16 90.9 Myxococcales yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 ko:K15034 ko00000,ko03012 Bacteria 1RH75@1224,2WR6W@28221,2Z1VX@29,42UF8@68525,COG1186@1,COG1186@2 NA|NA|NA J RF-1 domain MAG.T2.42_01818 1192034.CAP_8891 6.8e-35 154.8 Myxococcales ko:K07098 ko00000 Bacteria 1MUH5@1224,2WIMQ@28221,2YYKM@29,42Q51@68525,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T2.42_01820 497964.CfE428DRAFT_0572 5.5e-61 242.3 Verrucomicrobia Bacteria 46T3U@74201,COG3488@1,COG3488@2 NA|NA|NA C Di-haem oxidoreductase, putative peroxidase MAG.T2.42_01821 1304275.C41B8_06922 1.9e-77 295.8 Gammaproteobacteria cmoA GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 2.8.1.10 ko:K03149,ko:K15256 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000,ko03016 Bacteria 1MV4M@1224,1RMWY@1236,COG0500@1,COG2226@2 NA|NA|NA Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) MAG.T2.42_01822 1304275.C41B8_06927 2.8e-55 222.6 Gammaproteobacteria Bacteria 1RJNV@1224,1SGB2@1236,COG2020@1,COG2020@2 NA|NA|NA O Phospholipid methyltransferase MAG.T2.42_01823 1142394.PSMK_30990 1.7e-149 536.6 Planctomycetes feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 2IYCI@203682,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system MAG.T2.42_01825 598467.BrE312_2861 1.8e-24 120.2 Gammaproteobacteria eutR GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009438,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019172,GO:0019243,GO:0019249,GO:0019438,GO:0019752,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042180,GO:0042182,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0046483,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617 ko:K04033 ko00000,ko03000 Bacteria 1Q3UX@1224,1RS88@1236,COG2207@1,COG2207@2 NA|NA|NA K transcriptional regulator MAG.T2.42_01826 85643.Tmz1t_3870 9e-176 623.6 Betaproteobacteria 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2VIFW@28216,COG3119@1,COG3119@2 NA|NA|NA P Pfam Sulfatase MAG.T2.42_01827 448385.sce5265 1.6e-49 203.4 Myxococcales M1-763 Bacteria 1MX4H@1224,2WJ2Y@28221,2YW6C@29,42PY0@68525,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T2.42_01828 1033743.CAES01000032_gene906 2e-58 233.0 Paenibacillaceae mhpD Bacteria 1TXA5@1239,26R3V@186822,4I67F@91061,COG0179@1,COG0179@2 NA|NA|NA Q fumarylacetoacetate hydrolase MAG.T2.42_01829 91464.S7335_1094 1.1e-28 132.9 Synechococcus pcaC 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1G6DQ@1117,1H0P3@1129,COG0599@1,COG0599@2 NA|NA|NA S homolog of gamma-carboxymuconolactone decarboxylase subunit MAG.T2.42_01830 394221.Mmar10_3054 4.6e-208 731.5 Hyphomonadaceae 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 1N75C@1224,2TVNG@28211,43ZF4@69657,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA E Alpha/beta hydrolase family MAG.T2.42_01832 261292.Nit79A3_2951 1.4e-26 127.5 Bacteria 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria COG4625@1,COG4625@2 NA|NA|NA T pathogenesis MAG.T2.42_01834 1229172.JQFA01000002_gene2105 1.6e-19 102.4 Oscillatoriales 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 Bacteria 1G57H@1117,1HATA@1150,COG4948@1,COG4948@2 NA|NA|NA M Domain of unknown function (DUF4433) MAG.T2.42_01836 857087.Metme_0414 5.6e-44 186.0 Bacteria ko:K03328 ko00000 2.A.66.2 Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process MAG.T2.42_01837 203124.Tery_2983 2.1e-19 101.7 Oscillatoriales rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0040007,GO:0042594,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1G7SA@1117,1HC43@1150,COG0254@1,COG0254@2 NA|NA|NA J Binds the 23S rRNA MAG.T2.42_01838 1142394.PSMK_19340 1.6e-85 323.2 Planctomycetes prfB GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.1.80,3.1.1.61 ko:K02835,ko:K02836,ko:K02839,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03012 Bacteria 2IY77@203682,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA MAG.T2.42_01842 987059.RBXJA2T_05318 6.6e-294 1017.7 unclassified Burkholderiales Bacteria 1KJSD@119065,1MUIQ@1224,2VKH5@28216,COG1075@1,COG1075@2,COG4995@1,COG4995@2 NA|NA|NA S CHAT domain MAG.T2.42_01843 298655.KI912266_gene6492 1.5e-20 106.3 Bacteria pntA-2 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria COG3288@1,COG3288@2 NA|NA|NA C NAD(P)+ transhydrogenase (AB-specific) activity MAG.T2.42_01847 886293.Sinac_3357 9e-120 437.2 Planctomycetes ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 2IXBA@203682,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase, FAD-containing subunit MAG.T2.42_01850 1142394.PSMK_11750 8.7e-09 68.2 Planctomycetes ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2IY62@203682,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Belongs to the GSP D family MAG.T2.42_01851 1142394.PSMK_11750 2.7e-08 66.2 Planctomycetes ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2IY62@203682,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Belongs to the GSP D family MAG.T2.42_01853 452637.Oter_1490 7.3e-11 74.3 Bacteria ko:K07337 ko00000 Bacteria COG3417@1,COG3417@2 NA|NA|NA M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) MAG.T2.42_01855 1089552.KI911559_gene1854 9.2e-13 82.0 Rhodospirillales Bacteria 1RA9U@1224,2JVW4@204441,2U5MF@28211,COG3014@1,COG3014@2 NA|NA|NA S protein conserved in bacteria MAG.T2.42_01857 118168.MC7420_150 3.2e-86 325.5 Oscillatoriales yfbL Bacteria 1G1QW@1117,1H7N7@1150,COG2234@1,COG2234@2 NA|NA|NA S PFAM Peptidase family M28 MAG.T2.42_01858 32057.KB217478_gene6503 1.7e-12 78.2 Nostocales Bacteria 1G9I1@1117,1HPTW@1161,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 MAG.T2.42_01859 485918.Cpin_6839 5e-85 321.6 Sphingobacteriia sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 Bacteria 1IP4Q@117747,4NF33@976,COG0508@1,COG0508@2 NA|NA|NA C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) MAG.T2.42_01861 1501230.ET33_10715 1.3e-40 173.3 Paenibacillaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR90@1239,26UI1@186822,4HDK0@91061,COG1136@1,COG1136@2 NA|NA|NA V ATP-binding protein MAG.T2.42_01862 1142394.PSMK_11970 3.5e-249 868.2 Planctomycetes alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IX30@203682,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain MAG.T2.42_01863 1142394.PSMK_27450 1.7e-28 132.5 Planctomycetes Bacteria 2IZK3@203682,COG4747@1,COG4747@2 NA|NA|NA S COG4747 ACT domain-containing protein MAG.T2.42_01864 530564.Psta_0999 6.4e-39 168.3 Planctomycetes 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 2IZQS@203682,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.42_01865 1142394.PSMK_29240 1.3e-34 153.7 Bacteria ygcM 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria COG0720@1,COG0720@2 NA|NA|NA H synthase MAG.T2.42_01866 314230.DSM3645_27256 6.7e-20 104.4 Planctomycetes Bacteria 2A5UW@1,2IZAT@203682,30UKM@2 NA|NA|NA MAG.T2.42_01867 1142394.PSMK_30320 5.4e-37 161.0 Planctomycetes ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IZJS@203682,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group MAG.T2.42_01868 656024.FsymDg_4258 4.2e-71 274.6 Frankiales macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GK3I@201174,4EU28@85013,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T2.42_01869 3218.PP1S154_79V6.1 2e-167 595.9 Streptophyta ASA1 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009507,GO:0009536,GO:0009889,GO:0009987,GO:0010600,GO:0010817,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019222,GO:0019438,GO:0019752,GO:0031323,GO:0031326,GO:0032350,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046885,GO:0050789,GO:0050794,GO:0065007,GO:0065008,GO:0071704,GO:0090354,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Viridiplantae 37PW6@33090,3G7PU@35493,COG0147@1,KOG1223@2759 NA|NA|NA E Anthranilate synthase MAG.T2.42_01870 1142394.PSMK_15360 5.5e-73 282.7 Planctomycetes ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 2IX9Q@203682,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.42_01871 861299.J421_2862 8.4e-75 286.6 Gemmatimonadetes ahcY GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 1ZTEF@142182,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine MAG.T2.42_01874 765912.Thimo_1760 4.4e-51 208.8 Chromatiales ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 1MUEG@1224,1RQ6Z@1236,1WWM0@135613,COG1840@1,COG1840@2 NA|NA|NA P extracellular solute-binding protein MAG.T2.42_01875 234267.Acid_1209 6.1e-47 194.1 Acidobacteria ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 3Y589@57723,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_01876 391625.PPSIR1_06878 1.7e-44 185.7 Myxococcales hit ko:K02503 ko00000,ko04147 Bacteria 1PDTP@1224,2WS0J@28221,2Z2ZP@29,42UAD@68525,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain MAG.T2.42_01878 1121123.AUAO01000002_gene490 5.7e-60 238.0 Caulobacterales nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0C@1224,2KFMV@204458,2TS7C@28211,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family MAG.T2.42_01879 1192034.CAP_0976 1.9e-20 106.7 Myxococcales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1MWCC@1224,2WMAF@28221,2YVIU@29,42P6I@68525,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor MAG.T2.42_01881 390989.JOEG01000010_gene427 2.7e-65 255.4 Micromonosporales Bacteria 2GPB4@201174,4D8DE@85008,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family MAG.T2.42_01887 1142394.PSMK_29820 3.3e-65 255.8 Planctomycetes 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2IXB8@203682,COG0472@1,COG0472@2 NA|NA|NA M PFAM Glycosyl transferase family 4 MAG.T2.42_01888 1142394.PSMK_20610 4.7e-72 278.1 Planctomycetes cdsA2 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748,ko:K09949 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 Bacteria 2IXGX@203682,COG3494@1,COG3494@2 NA|NA|NA S Protein of unknown function (DUF1009) MAG.T2.42_01889 1504672.669786243 7.1e-129 468.0 Proteobacteria Bacteria 1QVJR@1224,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_01890 365044.Pnap_1203 1.1e-131 477.6 Comamonadaceae Bacteria 1QWF7@1224,2WHK2@28216,4AJYX@80864,COG4249@1,COG4249@2 NA|NA|NA S Caspase domain MAG.T2.42_01891 1142394.PSMK_02020 1e-35 157.1 Bacteria tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA methyltransferase RrmJ FtsJ MAG.T2.42_01892 1142394.PSMK_04560 2.1e-262 912.1 Planctomycetes gyrA 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2IY0U@203682,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T2.42_01896 1142394.PSMK_22060 1.1e-170 607.1 Planctomycetes recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IX1Q@203682,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) MAG.T2.42_01898 867903.ThesuDRAFT_01096 6.3e-29 134.4 Clostridiales incertae sedis smtA 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 Bacteria 1UF4M@1239,24B70@186801,3WDHB@538999,COG4122@1,COG4122@2 NA|NA|NA S Methyltransferase domain MAG.T2.42_01899 711393.AYRX01000040_gene6092 1.5e-19 104.4 Actinobacteria Bacteria 2GJSK@201174,COG2208@1,COG2208@2 NA|NA|NA T SMART protein phosphatase 2C domain protein MAG.T2.42_01900 1229487.AMYW01000029_gene2832 5.9e-55 221.1 Flavobacterium CP_0807 ko:K09125 ko00000 Bacteria 1I2GG@117743,2NU67@237,4NNPU@976,COG1738@1,COG1738@2 NA|NA|NA U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage MAG.T2.42_01903 662479.C440_05987 5.6e-145 521.5 Archaea Archaea COG1404@1,arCOG00702@2157 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_01904 1214101.BN159_0093 8.6e-21 107.8 Actinobacteria Bacteria 2AWE2@1,2GUTW@201174,31NA4@2 NA|NA|NA MAG.T2.42_01905 1214101.BN159_0094 2.6e-76 292.4 Bacteria Bacteria COG0189@1,COG0189@2 NA|NA|NA HJ Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) MAG.T2.42_01906 471852.Tcur_2667 1.4e-184 652.9 Streptosporangiales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 2GIWX@201174,4EGY7@85012,COG1643@1,COG1643@2 NA|NA|NA L Helicase associated domain (HA2) Add an annotation MAG.T2.42_01907 1492922.GY26_19840 2.3e-19 101.3 unclassified Gammaproteobacteria Bacteria 1J72G@118884,1N72W@1224,1S8YP@1236,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein MAG.T2.42_01908 344747.PM8797T_16740 4.3e-53 214.9 Planctomycetes mtfA ko:K09933 ko00000,ko01002 Bacteria 2IZES@203682,COG3228@1,COG3228@2 NA|NA|NA S Belongs to the MtfA family MAG.T2.42_01910 159450.NH14_07080 2.3e-62 245.7 Burkholderiaceae 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1K088@119060,1MU9Q@1224,2VHIC@28216,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter MAG.T2.42_01911 378806.STAUR_2896 9.5e-77 294.7 Myxococcales ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1MWF0@1224,2X5DP@28221,2YXPR@29,42PF3@68525,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P Bacterial periplasmic substrate-binding proteins MAG.T2.42_01912 1444309.JAQG01000012_gene2066 1.2e-110 406.8 Paenibacillaceae citZ 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPS@1239,26RV3@186822,4H9YE@91061,COG0372@1,COG0372@2 NA|NA|NA C Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate MAG.T2.42_01913 1142394.PSMK_31720 1.5e-29 137.5 Planctomycetes Bacteria 2IZZY@203682,COG0705@1,COG0705@2 NA|NA|NA S PFAM Rhomboid family MAG.T2.42_01914 1215092.PA6_027_01090 3.9e-31 141.7 Pseudomonas aeruginosa group trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1RA87@1224,1S41P@1236,1YD0W@136841,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family MAG.T2.42_01915 1142394.PSMK_11750 3.5e-08 66.6 Planctomycetes ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2IY62@203682,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Belongs to the GSP D family MAG.T2.42_01916 1294143.H681_21010 3.5e-41 177.9 Gammaproteobacteria Bacteria 1MUME@1224,1RNPC@1236,COG2885@1,COG2885@2,COG2982@1,COG2982@2 NA|NA|NA M Domain of Unknown Function (DUF748) MAG.T2.42_01918 522306.CAP2UW1_3092 3.4e-55 222.2 Betaproteobacteria Bacteria 1MV5I@1224,2VH9H@28216,COG0714@1,COG0714@2 NA|NA|NA S ATPase associated with various cellular activities, AAA_5 MAG.T2.42_01919 1123399.AQVE01000043_gene1564 1.1e-11 78.2 Thiotrichales 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1R4DB@1224,1SZFQ@1236,46384@72273,COG2909@1,COG2909@2 NA|NA|NA K TIR domain MAG.T2.42_01920 1142394.PSMK_15490 1.1e-79 304.3 Planctomycetes nuoN 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IXC6@203682,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.42_01921 530564.Psta_0731 3.3e-101 375.9 Planctomycetes 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IX79@203682,COG1008@1,COG1008@2 NA|NA|NA C proton-translocating NADH-quinone oxidoreductase, chain M MAG.T2.42_01922 1142394.PSMK_15510 1.8e-123 450.3 Planctomycetes nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341,ko:K12137 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Bacteria 2IX10@203682,COG1009@1,COG1009@2 NA|NA|NA CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 MAG.T2.42_01923 1142394.PSMK_15520 8e-24 116.7 Planctomycetes nuoK 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2J0GU@203682,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.42_01924 1142394.PSMK_15530 5e-33 148.7 Planctomycetes nuoJ 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2J0MC@203682,COG0839@1,COG0839@2 NA|NA|NA C PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 MAG.T2.42_01929 497964.CfE428DRAFT_4519 1.9e-65 256.1 Verrucomicrobia yafV 3.5.1.3 ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 46T1B@74201,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase MAG.T2.42_01932 76114.ebA1220 9e-49 201.4 Rhodocyclales 3.4.21.66 ko:K08651,ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1MU3S@1224,2KXGP@206389,2VMHQ@28216,COG1404@1,COG1404@2 NA|NA|NA M Subtilase family MAG.T2.42_01934 1142394.PSMK_19550 4e-113 415.2 Planctomycetes hflX ko:K03665 ko00000,ko03009 Bacteria 2IXH5@203682,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis MAG.T2.42_01935 1142394.PSMK_23290 1e-29 137.9 Planctomycetes Bacteria 2J0D1@203682,COG0705@1,COG0705@2 NA|NA|NA S PFAM Rhomboid family MAG.T2.42_01936 1123508.JH636443_gene5132 1.1e-36 161.0 Planctomycetes ywmF Bacteria 2J04B@203682,COG1994@1,COG1994@2 NA|NA|NA S PFAM Peptidase family M50 MAG.T2.42_01937 1123288.SOV_4c01730 3.6e-30 138.3 Negativicutes nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,4H4EZ@909932,COG0494@1,COG0494@2 NA|NA|NA L Hydrolase, NUDIX family MAG.T2.42_01938 1142394.PSMK_20630 3.8e-70 271.6 Planctomycetes ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IXBY@203682,COG1127@1,COG1127@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents, ATPase component MAG.T2.42_01939 1142394.PSMK_20620 1.1e-14 87.8 Bacteria ko:K02067,ko:K06192 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents, periplasmic component MAG.T2.42_01940 1142394.PSMK_15960 5.4e-17 94.7 Bacteria ko:K02557,ko:K11892 ko02030,ko02040,ko03070,map02030,map02040,map03070 M00334 ko00000,ko00001,ko00002,ko02000,ko02035,ko02044 1.A.30.1,3.A.23.1 Bacteria COG1360@1,COG1360@2 NA|NA|NA N Flagellar Motor Protein MAG.T2.42_01941 1142394.PSMK_18480 4.8e-51 209.1 Planctomycetes pilD 3.4.23.43 ko:K02236,ko:K02278,ko:K02506,ko:K02654,ko:K10966 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 2IZQ8@203682,COG1989@1,COG1989@2 NA|NA|NA NOU Bacterial Peptidase A24 N-terminal domain MAG.T2.42_01942 1123229.AUBC01000024_gene4586 3.9e-09 67.8 Bradyrhizobiaceae xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1PTYQ@1224,2UFD6@28211,3K0ER@41294,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T2.42_01943 1142394.PSMK_07190 2e-63 249.6 Planctomycetes murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2IYGQ@203682,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation MAG.T2.42_01944 1142394.PSMK_24040 1.5e-115 423.3 Planctomycetes murC 6.3.2.4,6.3.2.8 ko:K01921,ko:K01924 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2IYEH@203682,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family MAG.T2.42_01945 1142394.PSMK_17470 2.2e-151 542.3 Planctomycetes ko:K07713 ko02020,map02020 M00499 ko00000,ko00001,ko00002,ko02022 Bacteria 2IWYY@203682,COG2204@1,COG2204@2 NA|NA|NA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains MAG.T2.42_01946 1142394.PSMK_15800 9.2e-39 167.9 Planctomycetes ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 2IZHF@203682,COG0795@1,COG0795@2 NA|NA|NA S Permease YjgP YjgQ family MAG.T2.42_01947 1142394.PSMK_20920 7.3e-34 151.4 Bacteria 3.1.3.16,5.2.1.8 ko:K03769,ko:K07533,ko:K20074 ko00000,ko01000,ko01009,ko03110 Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity MAG.T2.42_01949 1142394.PSMK_12770 1.2e-55 224.9 Planctomycetes Bacteria 2IX04@203682,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family MAG.T2.42_01950 243233.MCA2161 1.3e-128 467.6 Gammaproteobacteria ko:K03615,ko:K09690 ko02010,map02010 M00250 ko00000,ko00001,ko00002,ko02000 3.A.1.103 Bacteria 1QX0J@1224,1RZ5A@1236,COG3206@1,COG3206@2 NA|NA|NA M protein involved in exopolysaccharide biosynthesis MAG.T2.42_01951 497964.CfE428DRAFT_2609 2.4e-112 412.5 Verrucomicrobia pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 46S78@74201,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily MAG.T2.42_01953 1142394.PSMK_08320 1.2e-14 85.1 Planctomycetes rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J1HX@203682,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family MAG.T2.42_01955 1142394.PSMK_08330 8.5e-16 90.1 Planctomycetes secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2J0E7@203682,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation MAG.T2.42_01956 1142394.PSMK_08340 4.3e-70 271.6 Planctomycetes nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2IZ9N@203682,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination MAG.T2.42_01957 502025.Hoch_5894 8e-27 128.3 Myxococcales Bacteria 1MWMM@1224,2WRHR@28221,2Z341@29,42WIB@68525,COG5459@1,COG5459@2 NA|NA|NA J Mitochondrial small ribosomal subunit Rsm22 MAG.T2.42_01958 1123242.JH636438_gene5714 3.8e-31 141.4 Planctomycetes ko:K07071 ko00000 Bacteria 2J0FI@203682,COG4276@1,COG4276@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport MAG.T2.42_01959 1142394.PSMK_12790 3.6e-63 248.8 Planctomycetes Bacteria 2IY6G@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.42_01960 1120965.AUBV01000006_gene2165 1e-24 120.9 Cytophagia Bacteria 47MMC@768503,4NGYE@976,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) MAG.T2.42_01961 481448.Minf_0612 5.2e-36 157.9 unclassified Verrucomicrobia glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 37GHA@326457,46V4E@74201,COG0580@1,COG0580@2 NA|NA|NA G Major intrinsic protein MAG.T2.42_01962 335543.Sfum_0447 2.6e-101 375.9 Deltaproteobacteria Bacteria 1MUA8@1224,2WIQX@28221,42MRU@68525,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM RND efflux system, outer membrane lipoprotein, NodT MAG.T2.42_01963 247490.KSU1_D0550 6.7e-76 291.2 Planctomycetes ko:K01993 ko00000 Bacteria 2IYUX@203682,COG0845@1,COG0845@2 NA|NA|NA M PFAM secretion protein HlyD MAG.T2.42_01964 247490.KSU1_D0549 1.9e-82 312.4 Planctomycetes hrtA ko:K02003,ko:K09810,ko:K09814 ko02010,map02010 M00255,M00257,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2IYS3@203682,COG1136@1,COG1136@2 NA|NA|NA V PFAM ABC transporter MAG.T2.42_01965 247490.KSU1_D0548 1.6e-144 519.2 Planctomycetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IWXH@203682,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T2.42_01966 335543.Sfum_0446 3.6e-47 195.3 Syntrophobacterales Bacteria 1NDME@1224,2MRS7@213462,2WKKZ@28221,42MYP@68525,COG1309@1,COG1309@2 NA|NA|NA K Domain of unknown function (DUF1956) MAG.T2.42_01969 926550.CLDAP_09620 1.5e-40 173.7 Chloroflexi Bacteria 2G6J2@200795,COG4260@1,COG4260@2 NA|NA|NA S SPFH domain-Band 7 family MAG.T2.42_01970 926550.CLDAP_09630 1.7e-15 89.4 Chloroflexi Bacteria 2G9CR@200795,33AIT@2,arCOG05710@1 NA|NA|NA MAG.T2.42_01972 1142394.PSMK_02570 6.4e-68 266.2 Planctomycetes comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2IY17@203682,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S competence protein ComEC Rec2 MAG.T2.42_01973 861299.J421_0476 1.6e-27 131.7 Gemmatimonadetes Bacteria 1ZTK4@142182,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Tetratricopeptide repeat MAG.T2.42_01975 765869.BDW_03850 1.4e-64 253.4 Bdellovibrionales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1MVE3@1224,2MT7S@213481,2WMSH@28221,42M2I@68525,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T2.42_01976 502025.Hoch_6539 7.8e-23 115.9 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_01978 886293.Sinac_0207 1.2e-68 267.3 Bacteria ugtP 2.4.1.315 ko:K03429 ko00561,ko01100,map00561,map01100 R02689,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT28 Bacteria COG0707@1,COG0707@2 NA|NA|NA M undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity MAG.T2.42_01979 1142394.PSMK_20820 1.1e-107 396.7 Planctomycetes mgtA_2 Bacteria 2IYWS@203682,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T2.42_01980 1470591.BW41_01888 4.3e-78 298.1 Sphingomonadales lpxH_2 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MVKD@1224,2K0Q8@204457,2TSEB@28211,COG2908@1,COG2908@2 NA|NA|NA S protein conserved in bacteria MAG.T2.42_01981 1232683.ADIMK_3434 1.4e-46 193.0 Alteromonadaceae marC ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1MV1C@1224,1RPM8@1236,46AR2@72275,COG2095@1,COG2095@2 NA|NA|NA U MarC family integral membrane protein MAG.T2.42_01982 42256.RradSPS_0385 3.1e-70 272.7 Rubrobacteria cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2IQ8T@201174,4CPMK@84995,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Competence-damaged protein MAG.T2.42_01983 1122132.AQYH01000018_gene1110 2.8e-32 145.2 Rhizobiaceae folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940,ko:K17488 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R10348,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC02504,RC03131,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iLJ478.TM0041,iSBO_1134.SBO_0131 Bacteria 1MZH8@1224,2U8D6@28211,4BMRA@82115,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MAG.T2.42_01984 929713.NIASO_08790 3.5e-21 109.8 Sphingobacteriia Bacteria 1IRSC@117747,4NKFI@976,COG0526@1,COG0526@2 NA|NA|NA CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T2.42_01985 595460.RRSWK_02803 2.6e-21 110.2 Planctomycetes Bacteria 2IXG6@203682,COG0526@1,COG0526@2 NA|NA|NA CO Thiol-disulfide isomerase and MAG.T2.42_01986 357808.RoseRS_3858 3.1e-214 752.3 Chloroflexia MA20_43170 ko:K06911 ko00000 Bacteria 2G5ZQ@200795,376AA@32061,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidase domain protein MAG.T2.42_01988 1142394.PSMK_07940 6.8e-34 150.2 Planctomycetes ko:K07107 ko00000,ko01000 Bacteria 2J0BH@203682,COG0824@1,COG0824@2 NA|NA|NA S thioesterase MAG.T2.42_01989 1142394.PSMK_15430 8.9e-55 221.5 Planctomycetes mnmE ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 2IWUB@203682,COG0486@1,COG0486@2 NA|NA|NA J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 MAG.T2.42_01990 1142394.PSMK_15440 1.7e-81 310.8 Planctomycetes ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2IYA0@203682,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins MAG.T2.42_01991 1142394.PSMK_14290 2.1e-87 328.9 Planctomycetes apaH Bacteria 2IYH6@203682,COG0639@1,COG0639@2 NA|NA|NA T COG0639 Diadenosine tetraphosphatase and related MAG.T2.42_01992 1142394.PSMK_08090 2.9e-151 542.0 Planctomycetes lpdA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IX5H@203682,COG1249@1,COG1249@2 NA|NA|NA C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) MAG.T2.42_01993 1219035.NT2_21_00080 1.6e-70 273.5 Sphingomonadales ko:K07133 ko00000 Bacteria 1MWBT@1224,2K9E1@204457,2U050@28211,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T2.42_01994 525904.Tter_1994 5.9e-41 174.5 Bacteria 2.3.1.128,2.3.1.82 ko:K00663,ko:K03790 ko00000,ko01000,ko01504,ko03009 Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T2.42_01996 1312959.KI914647_gene104 3.7e-29 135.2 Bacteria Bacteria COG0500@1,COG0500@2 NA|NA|NA Q methyltransferase activity MAG.T2.42_01997 648996.Theam_1402 8.5e-42 177.2 Aquificae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2G3ZQ@200783,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP MAG.T2.42_01999 765911.Thivi_3036 1.1e-26 127.9 Gammaproteobacteria Bacteria 1RD10@1224,1SV6B@1236,COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T2.42_02004 886293.Sinac_6401 1.3e-61 243.8 Planctomycetes dprA ko:K04096 ko00000 Bacteria 2IX3D@203682,COG0758@1,COG0758@2,COG1948@1,COG1948@2 NA|NA|NA L TIGRFAM DNA protecting protein DprA MAG.T2.42_02006 648996.Theam_0490 8.3e-41 174.1 Aquificae Bacteria 2G41R@200783,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain MAG.T2.42_02007 756272.Plabr_3504 1.4e-108 400.2 Bacteria Bacteria COG0464@1,COG0464@2 NA|NA|NA O ATPase activity MAG.T2.42_02010 478741.JAFS01000002_gene628 3.1e-28 133.7 unclassified Verrucomicrobia ccsA Bacteria 37GGG@326457,46VBM@74201,COG0755@1,COG0755@2 NA|NA|NA O Cytochrome C assembly protein MAG.T2.42_02011 105420.BBPO01000099_gene6270 2.3e-77 296.6 Streptacidiphilus 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183 ko00500,ko00520,ko01100,map00500,map00520,map01100 R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 GH18,GH5,GH9 Bacteria 2GJTU@201174,2NFP5@228398,COG3469@1,COG3469@2 NA|NA|NA G CBD_II MAG.T2.42_02012 498761.HM1_0103 2e-102 379.4 Clostridia pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iJN678.pfkA Bacteria 1TPF4@1239,249AM@186801,COG0205@1,COG0205@2 NA|NA|NA H Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T2.42_02013 1142394.PSMK_26450 1.9e-41 176.0 Planctomycetes 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2J080@203682,COG0241@1,COG0241@2 NA|NA|NA E HAD-hyrolase-like MAG.T2.42_02015 1142394.PSMK_06170 1.3e-41 177.2 Planctomycetes rfaF 2.7.1.167,2.7.7.70 ko:K02841,ko:K02843,ko:K02849,ko:K03272 ko00540,ko01100,map00540,map01100 M00064,M00080 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 2IXD5@203682,COG0859@1,COG0859@2 NA|NA|NA M PFAM glycosyl transferase family 9 MAG.T2.42_02016 1255043.TVNIR_2165 4.3e-27 128.3 Bacteria inaA 2.7.11.1,3.6.1.27 ko:K02848,ko:K07178,ko:K19302 ko00540,ko00550,ko01100,ko03008,map00540,map00550,map01100,map03008 M00080 R05627 RC00002 ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko01011,ko03009 Bacteria COG3642@1,COG3642@2 NA|NA|NA T kinase activity MAG.T2.42_02017 690850.Desaf_0024 3.8e-38 165.2 Desulfovibrionales lgtF ko:K12984 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 Bacteria 1PVP4@1224,2MHBU@213115,2WNU9@28221,42M23@68525,COG0463@1,COG0463@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.42_02018 1142394.PSMK_15030 2.3e-37 162.5 Planctomycetes plsY 2.3.1.15 ko:K03977,ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko03009 Bacteria 2J0DJ@203682,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP MAG.T2.42_02019 1142394.PSMK_16390 8.4e-08 65.5 Bacteria Bacteria COG1714@1,COG1714@2 NA|NA|NA S RDD family MAG.T2.42_02021 530564.Psta_3007 3.3e-10 72.0 Planctomycetes Bacteria 2BWMY@1,2J0M4@203682,331GB@2 NA|NA|NA MAG.T2.42_02022 1142394.PSMK_18500 2e-53 216.1 Planctomycetes dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 2IZSP@203682,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria MAG.T2.42_02024 240016.ABIZ01000001_gene5681 2.7e-75 289.3 Verrucomicrobiae Bacteria 2IUKB@203494,46T50@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T2.42_02025 497964.CfE428DRAFT_5350 8e-24 116.7 Verrucomicrobia Bacteria 46SWV@74201,COG5267@1,COG5267@2 NA|NA|NA S Protein of unknown function (DUF1800) MAG.T2.42_02026 1142394.PSMK_23130 5.5e-142 510.8 Planctomycetes gmd GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 R00888 RC00402 ko00000,ko00001,ko01000 Bacteria 2IWZ4@203682,COG1089@1,COG1089@2 NA|NA|NA M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose MAG.T2.42_02027 1142394.PSMK_23120 3.1e-114 418.3 Planctomycetes fcl 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 R05692 RC01014 ko00000,ko00001,ko01000 Bacteria 2IYBF@203682,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction MAG.T2.42_02028 886293.Sinac_6393 1.2e-84 320.5 Planctomycetes wbjE Bacteria 2IZS5@203682,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T2.42_02029 90814.KL370892_gene2009 7.3e-50 203.8 Gammaproteobacteria wcaF 2.3.1.79 ko:K00661,ko:K03818 ko00000,ko01000 Bacteria 1R6A3@1224,1RQXV@1236,COG0110@1,COG0110@2 NA|NA|NA S colanic acid biosynthesis acetyltransferase wcaF MAG.T2.42_02030 1142394.PSMK_00740 5.4e-67 262.3 Planctomycetes waaE ko:K12984 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 Bacteria 2J11G@203682,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T2.42_02031 1115512.EH105704_03_00440 8.8e-36 157.1 Escherichia wcaF GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 2.3.1.79 ko:K00661,ko:K03818 ko00000,ko01000 Bacteria 1R6A3@1224,1RQXV@1236,3XN6J@561,COG0110@1,COG0110@2 NA|NA|NA S slime layer organization MAG.T2.42_02033 756272.Plabr_0350 3.1e-135 488.8 Planctomycetes cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IX9C@203682,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T2.42_02034 266117.Rxyl_0824 3.3e-35 155.6 Rubrobacteria prmA_2 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 Bacteria 2GTAU@201174,4CQPT@84995,COG3897@1,COG3897@2 NA|NA|NA S Lysine methyltransferase MAG.T2.42_02035 1123508.JH636451_gene5985 1.7e-36 159.5 Planctomycetes coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 ko:K00859,ko:K07566 ko00770,ko01100,map00770,map01100 M00120 R00130,R10463 RC00002,RC00078,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 Bacteria 2J02E@203682,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A MAG.T2.42_02036 247490.KSU1_C0414 9.3e-150 537.0 Planctomycetes rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 2IXV3@203682,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T2.42_02038 1142394.PSMK_03510 1.6e-42 179.5 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ91@203682,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.42_02041 344747.PM8797T_17464 1.3e-23 115.9 Planctomycetes rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J02D@203682,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit MAG.T2.42_02042 1142394.PSMK_21340 1.1e-76 293.5 Planctomycetes rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IY9P@203682,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family MAG.T2.42_02043 1142394.PSMK_21350 5.3e-49 201.4 Planctomycetes tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2IZGM@203682,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome MAG.T2.42_02044 530564.Psta_2628 2.7e-24 117.9 Planctomycetes Bacteria 2J0RB@203682,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family MAG.T2.42_02045 1142394.PSMK_13110 3e-56 225.3 Planctomycetes 5.1.3.35 ko:K19974 ko00525,ko01130,map00525,map01130 M00814 R11081 RC01519 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXZ6@203682,COG1082@1,COG1082@2 NA|NA|NA G isomerase MAG.T2.42_02046 1142394.PSMK_03830 2.2e-38 165.6 Bacteria Bacteria 2EDBD@1,3377P@2 NA|NA|NA MAG.T2.42_02047 1142394.PSMK_03820 1.6e-22 114.0 Bacteria Bacteria 2EVR7@1,33P56@2 NA|NA|NA MAG.T2.42_02048 1142394.PSMK_26160 4.6e-90 338.2 Planctomycetes mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1,2.7.3.2,2.7.3.3 ko:K00933,ko:K00934,ko:K19405 ko00330,ko01100,map00330,map01100 M00047 R00554,R01881,R11090 RC00002,RC00203 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IXJG@203682,COG3869@1,COG3869@2 NA|NA|NA H Catalyzes the specific phosphorylation of arginine residues in proteins MAG.T2.42_02049 1142394.PSMK_26150 5.1e-19 101.3 Planctomycetes CP_0046 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 2J09E@203682,COG3880@1,COG3880@2 NA|NA|NA S protein with conserved CXXC pairs MAG.T2.42_02050 1142394.PSMK_16120 4.7e-77 294.7 Planctomycetes kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IXME@203682,COG2877@1,COG2877@2 NA|NA|NA M 8-phosphate synthase MAG.T2.42_02051 755178.Cyan10605_2924 1.8e-19 102.4 Cyanobacteria phhB 3.5.4.33,4.2.1.96 ko:K01724,ko:K11991 ko00790,map00790 R04734,R10223 RC00477,RC01208 ko00000,ko00001,ko01000,ko03016,ko04147 Bacteria 1G7P9@1117,COG2154@1,COG2154@2 NA|NA|NA H pterin-4-alpha-carbinolamine dehydratase MAG.T2.42_02052 1142394.PSMK_18340 3.4e-45 188.7 Planctomycetes gluQ 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2IYG3@203682,COG0008@1,COG0008@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T2.42_02053 1142394.PSMK_18350 1.1e-14 87.0 Planctomycetes ko:K09005 ko00000 Bacteria 2J462@203682,COG1430@1,COG1430@2 NA|NA|NA S Uncharacterized ACR, COG1430 MAG.T2.42_02055 1142394.PSMK_05980 3.4e-53 216.1 Planctomycetes sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 2J09U@203682,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family MAG.T2.42_02056 1142394.PSMK_13590 1.9e-27 129.0 Planctomycetes ptsN 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IZ73@203682,COG1762@1,COG1762@2 NA|NA|NA G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 MAG.T2.42_02059 1142394.PSMK_11590 2.6e-72 279.3 Planctomycetes ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 2IY72@203682,COG0568@1,COG0568@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.42_02060 1382306.JNIM01000001_gene1981 2e-45 188.7 Chloroflexi ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 2G6NP@200795,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate MAG.T2.42_02061 1123501.KB902299_gene3662 6.4e-91 341.3 Alphaproteobacteria aatA 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1MW0Z@1224,2TRPK@28211,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase MAG.T2.42_02062 1123508.JH636453_gene5805 2.4e-13 84.0 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IY8U@203682,COG3391@1,COG3391@2 NA|NA|NA M Integrin alpha (beta-propellor repeats). MAG.T2.42_02063 1254432.SCE1572_51360 8.9e-23 115.5 Myxococcales Bacteria 1RKYF@1224,2WP82@28221,2YU4W@29,42T64@68525,COG1651@1,COG1651@2 NA|NA|NA O Thioredoxin MAG.T2.42_02064 28072.Nos7524_0910 7e-78 298.1 Nostocales Bacteria 1G3T3@1117,1HNHF@1161,COG3385@1,COG3385@2 NA|NA|NA L PFAM Transposase DDE domain MAG.T2.42_02066 1267535.KB906767_gene5535 1.4e-37 164.5 Acidobacteria rsbU 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 Bacteria 3Y4DC@57723,COG1716@1,COG1716@2,COG2203@1,COG2203@2,COG2208@1,COG2208@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain MAG.T2.42_02068 94122.Shewana3_0285 2.1e-13 81.3 Shewanellaceae yqaE GO:0008150,GO:0042221,GO:0046677,GO:0050896 Bacteria 1N7K3@1224,1SGD5@1236,2QCT8@267890,COG0401@1,COG0401@2 NA|NA|NA S Proteolipid membrane potential modulator MAG.T2.42_02072 1499967.BAYZ01000028_gene1267 1e-43 185.3 unclassified Bacteria Bacteria 2NRSS@2323,COG4249@1,COG4249@2 NA|NA|NA S Peptidase C13 family MAG.T2.42_02073 411902.CLOBOL_02415 1.1e-35 158.7 Lachnoclostridium Bacteria 1TQ2M@1239,21Z2R@1506553,24CD5@186801,COG1404@1,COG1404@2 NA|NA|NA M Subtilase family MAG.T2.42_02074 1280950.HJO_07847 6.9e-34 150.6 Hyphomonadaceae Bacteria 1Q4JU@1224,2V6I0@28211,43ZSQ@69657,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein MAG.T2.42_02075 394221.Mmar10_1143 1.1e-19 102.8 Hyphomonadaceae Bacteria 1RIJ9@1224,2UVS4@28211,4411C@69657,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T2.42_02076 794903.OPIT5_17215 4.2e-12 79.0 Bacteria Bacteria 2EGE2@1,33A5Z@2 NA|NA|NA MAG.T2.42_02079 1121918.ARWE01000001_gene1658 2.7e-57 229.2 Desulfuromonadales nodI ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 Bacteria 1MUX3@1224,2WM7T@28221,42MV1@68525,43TRG@69541,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system MAG.T2.42_02080 1304872.JAGC01000003_gene3070 3.5e-32 145.6 Desulfovibrionales nodJ ko:K09694 ko02010,map02010 M00252 ko00000,ko00001,ko00002,ko02000 3.A.1.102 Bacteria 1N55T@1224,2MA60@213115,2WK3B@28221,42N8F@68525,COG0842@1,COG0842@2 NA|NA|NA V PFAM ABC-2 type transporter MAG.T2.42_02082 682795.AciX8_2885 1.2e-146 526.2 Acidobacteriia gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2620,iNJ661.Rv1122 Bacteria 2JJT6@204432,3Y2ZP@57723,COG1023@1,COG1023@2 NA|NA|NA G 6-phosphogluconate dehydrogenase, C-terminal domain MAG.T2.42_02083 1040989.AWZU01000008_gene3776 3.6e-191 674.5 Bradyrhizobiaceae zwf 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUN0@1224,2U0D0@28211,3JURI@41294,COG0364@1,COG0364@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase, NAD binding domain MAG.T2.42_02084 404589.Anae109_0599 6.7e-69 267.3 Proteobacteria pgl 3.1.1.31,5.3.1.9 ko:K01057,ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00006,M00008,M00114 R02035,R02739,R02740,R03321 RC00376,RC00537,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1R5K6@1224,COG0363@1,COG0363@2 NA|NA|NA G 6-phosphogluconolactonase MAG.T2.42_02085 886293.Sinac_2019 5.4e-48 197.2 Planctomycetes rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2621 Bacteria 2IZSB@203682,COG0698@1,COG0698@2 NA|NA|NA G Ribose/Galactose Isomerase MAG.T2.42_02086 1380394.JADL01000007_gene4557 1.8e-308 1064.7 Rhodospirillales tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUEY@1224,2JVG7@204441,2TQUX@28211,COG0021@1,COG0021@2 NA|NA|NA G Transketolase, thiamine diphosphate binding domain MAG.T2.42_02087 1267533.KB906733_gene3472 5.3e-87 329.7 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_02088 502025.Hoch_1576 1.4e-35 156.4 Myxococcales ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1RINW@1224,2X3FI@28221,2YVVV@29,4385N@68525,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_02089 81824.XP_001747894.1 1.7e-116 426.0 Opisthokonta HOM2 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009088,GO:0009090,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Opisthokonta 38FPW@33154,COG0136@1,KOG4777@2759 NA|NA|NA E aspartate-semialdehyde dehydrogenase activity MAG.T2.42_02090 1122179.KB890451_gene4532 1.7e-15 90.1 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T2.42_02092 243090.RB8562 1.7e-33 148.7 Planctomycetes gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 2IX1K@203682,COG0696@1,COG0696@2 NA|NA|NA F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate MAG.T2.42_02093 1142394.PSMK_29570 2.5e-58 232.3 Planctomycetes yggS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 ko:K06997 ko00000 Bacteria 2IZ9R@203682,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MAG.T2.42_02096 1142394.PSMK_10320 3.1e-52 211.8 Planctomycetes tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZHI@203682,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis MAG.T2.42_02097 1396418.BATQ01000030_gene5617 1.1e-32 148.3 Bacteria Bacteria COG1538@1,COG1538@2 NA|NA|NA MU efflux transmembrane transporter activity MAG.T2.42_02098 1142394.PSMK_16410 7e-101 375.6 Bacteria 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria COG1874@1,COG1874@2 NA|NA|NA G beta-galactosidase activity MAG.T2.42_02099 1120936.KB907208_gene547 9.5e-53 213.8 Streptosporangiales 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSN@201174,4EHBQ@85012,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T2.42_02102 886293.Sinac_4624 1.2e-15 90.1 Planctomycetes Bacteria 2EDV6@1,2J12E@203682,337QB@2 NA|NA|NA MAG.T2.42_02103 886293.Sinac_6284 2.9e-28 131.0 Planctomycetes yfjA Bacteria 2J0M7@203682,COG4842@1,COG4842@2 NA|NA|NA S Proteins of 100 residues with WXG MAG.T2.42_02104 1142394.PSMK_24070 2.2e-90 340.1 Planctomycetes ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2IY5J@203682,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle MAG.T2.42_02108 1142394.PSMK_29720 3.1e-40 171.8 Planctomycetes pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZA7@203682,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) MAG.T2.42_02109 352165.HMPREF7215_1007 8.6e-121 440.7 Bacteria amyA 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH57 Bacteria COG1449@1,COG1449@2 NA|NA|NA G Belongs to the glycosyl hydrolase 57 family MAG.T2.42_02110 1142394.PSMK_10920 1e-282 979.5 Planctomycetes ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 2IWX2@203682,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) MAG.T2.42_02111 903814.ELI_3706 9.8e-14 85.1 Eubacteriaceae icfG 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 1TQY5@1239,249WB@186801,25XB2@186806,COG2208@1,COG2208@2 NA|NA|NA KT Sigma factor PP2C-like phosphatases MAG.T2.42_02112 869210.Marky_1180 7.3e-21 107.1 Deinococcus-Thermus metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1WIEF@1297,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation MAG.T2.42_02114 1142394.PSMK_07330 2.8e-68 265.0 Planctomycetes rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IYUB@203682,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit MAG.T2.42_02115 926562.Oweho_2634 5.3e-177 627.9 Cryomorphaceae purF 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1HXZE@117743,2PAAI@246874,4NFSM@976,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine MAG.T2.42_02116 1142394.PSMK_23050 1.5e-38 166.8 Planctomycetes Bacteria 2IZQK@203682,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T2.42_02117 572477.Alvin_0821 2.6e-43 182.6 Chromatiales lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1QKYH@1224,1S0N9@1236,1WXE9@135613,COG1043@1,COG1043@2 NA|NA|NA I Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.42_02120 314230.DSM3645_05355 1.3e-103 383.3 Planctomycetes ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 2IY8K@203682,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner MAG.T2.42_02121 1142394.PSMK_08120 5.8e-77 295.8 Planctomycetes 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 2IXAE@203682,COG0768@1,COG0768@2 NA|NA|NA M Penicillin binding protein transpeptidase domain MAG.T2.42_02122 1142394.PSMK_08130 3.1e-75 289.3 Planctomycetes rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2IZRI@203682,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T2.42_02123 1142394.PSMK_01050 3.3e-46 192.2 Planctomycetes rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2J158@203682,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA MAG.T2.42_02124 1142394.PSMK_14030 4.3e-57 229.9 Planctomycetes ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IX4B@203682,COG1450@1,COG1450@2 NA|NA|NA NU general secretion pathway protein D MAG.T2.42_02125 1000565.METUNv1_02114 3.8e-19 102.1 Betaproteobacteria phoD 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1NITU@1224,2W3YR@28216,COG3540@1,COG3540@2 NA|NA|NA P Laminin B (Domain IV) MAG.T2.42_02131 1254432.SCE1572_47340 2.8e-83 315.8 Myxococcales cefD 5.1.1.17 ko:K04127,ko:K11325,ko:K21174 ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130 M00673,M00825 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXH1@1224,2WWMI@28221,2YTY1@29,43203@68525,COG0520@1,COG0520@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T2.42_02133 1142394.PSMK_19750 4.4e-48 198.0 Planctomycetes lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2IZCV@203682,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair MAG.T2.42_02134 1125863.JAFN01000001_gene752 2.7e-21 108.2 Deltaproteobacteria Bacteria 1N2JS@1224,2WQ4M@28221,42TR3@68525,COG1917@1,COG1917@2 NA|NA|NA S PFAM Cupin 2, conserved barrel domain protein MAG.T2.42_02136 662479.C440_14604 2e-06 60.1 Halobacteria Archaea 23SVC@183963,2XUXY@28890,COG1413@1,arCOG04653@2157 NA|NA|NA C COG1413 FOG HEAT repeat MAG.T2.42_02137 1142394.PSMK_03310 1.7e-62 247.3 Planctomycetes norM ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2IXGS@203682,COG0534@1,COG0534@2 NA|NA|NA V MatE MAG.T2.42_02138 1142394.PSMK_08460 2.5e-39 168.3 Planctomycetes rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ97@203682,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors MAG.T2.42_02139 247490.KSU1_C1198 6.2e-64 250.8 Planctomycetes rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IYQK@203682,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release MAG.T2.42_02140 1142394.PSMK_08480 8e-38 163.7 Planctomycetes rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0R0@203682,COG0244@1,COG0244@2 NA|NA|NA J ribosomal protein l10 MAG.T2.42_02141 756272.Plabr_2007 1.1e-26 126.3 Planctomycetes rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0AK@203682,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation MAG.T2.42_02143 1300345.LF41_605 1.5e-20 106.7 Gammaproteobacteria Bacteria 1NJDG@1224,1SH8A@1236,2DR4R@1,33A5Q@2 NA|NA|NA MAG.T2.42_02144 452637.Oter_0554 8.2e-119 434.1 Verrucomicrobia 6.5.1.1,6.5.1.6,6.5.1.7 ko:K07576,ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 46UFS@74201,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain MAG.T2.42_02145 243230.DR_1710 1e-25 122.5 Bacteria Bacteria 31CTK@2,arCOG05253@1 NA|NA|NA MAG.T2.42_02146 575540.Isop_2223 8.1e-12 78.2 Bacteria hmuO GO:0003674,GO:0003824,GO:0004392,GO:0005488,GO:0005575,GO:0006725,GO:0006778,GO:0006787,GO:0006788,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016491,GO:0016705,GO:0019439,GO:0020037,GO:0033013,GO:0033015,GO:0034641,GO:0042167,GO:0042168,GO:0042440,GO:0042592,GO:0044237,GO:0044248,GO:0044270,GO:0046149,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051187,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:0098771,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.14.15.20 ko:K21480 ko00860,ko01100,ko01110,map00860,map01100,map01110 R11579 RC01270 ko00000,ko00001,ko01000 Bacteria COG5398@1,COG5398@2 NA|NA|NA P heme oxygenase MAG.T2.42_02147 661478.OP10G_4632 4.6e-122 445.7 Bacteria Bacteria COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.42_02148 713586.KB900536_gene469 1.5e-13 84.3 Proteobacteria yuxJ Bacteria 1RCII@1224,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.42_02149 880073.Calab_2079 8e-34 151.8 unclassified Bacteria natB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2NPCQ@2323,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein MAG.T2.42_02150 1047013.AQSP01000052_gene2600 2.5e-61 242.7 unclassified Bacteria natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2NQE2@2323,COG4152@1,COG4152@2 NA|NA|NA S Domain of unknown function (DUF4162) MAG.T2.42_02151 575540.Isop_1665 7e-24 118.2 Bacteria Bacteria COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) MAG.T2.42_02152 575540.Isop_1666 1.4e-72 280.8 Bacteria 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.42_02153 344747.PM8797T_03935 2.6e-32 145.6 Planctomycetes Bacteria 2IXP3@203682,COG0457@1,COG0457@2 NA|NA|NA C Cytochrome c554 and c-prime MAG.T2.42_02154 1255043.TVNIR_1306 3.6e-157 562.0 Bacteria trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria COG3118@1,COG3118@2 NA|NA|NA O belongs to the thioredoxin family MAG.T2.42_02155 1178825.ALIH01000002_gene1113 3.3e-11 77.4 Flavobacteriia Bacteria 1HX4C@117743,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S PFAM ASPIC and UnbV MAG.T2.42_02156 1122176.KB903531_gene2955 3e-15 90.9 Sphingobacteriia Bacteria 1IYS6@117747,4NDUD@976,COG5276@1,COG5276@2 NA|NA|NA S cellulase activity MAG.T2.42_02157 693444.D782_3505 2.5e-09 71.2 Gammaproteobacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1MU7T@1224,1RMZW@1236,COG2373@1,COG2373@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2,COG4932@1,COG4932@2 NA|NA|NA Q von willebrand factor, type A MAG.T2.42_02158 497964.CfE428DRAFT_0572 1.1e-64 254.6 Verrucomicrobia Bacteria 46T3U@74201,COG3488@1,COG3488@2 NA|NA|NA C Di-haem oxidoreductase, putative peroxidase MAG.T2.42_02159 1123253.AUBD01000002_gene1152 4.1e-31 141.7 Xanthomonadales xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 ko:K03733 ko00000,ko03036 Bacteria 1MUJJ@1224,1RMJG@1236,1X31C@135614,COG4973@1,COG4973@2 NA|NA|NA L Belongs to the 'phage' integrase family. XerC subfamily MAG.T2.42_02161 575540.Isop_0606 6.5e-52 211.8 Planctomycetes Bacteria 2J0ZX@203682,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) MAG.T2.42_02162 1142394.PSMK_00360 4.9e-21 108.6 Bacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria COG2304@1,COG2304@2 NA|NA|NA IU oxidoreductase activity MAG.T2.42_02163 1123278.KB893598_gene2683 3.9e-11 76.6 Cytophagia 3.2.1.14,4.2.2.2 ko:K01183,ko:K01728 ko00040,ko00520,ko01100,ko02024,map00040,map00520,map01100,map02024 R01206,R02334,R02361,R06240 RC00049,RC00467,RC00705 ko00000,ko00001,ko01000 GH18 Bacteria 47YPT@768503,4PPN6@976,COG4733@1,COG4733@2 NA|NA|NA M Fibronectin type III domain MAG.T2.42_02164 1142394.PSMK_00340 4e-37 161.8 Planctomycetes ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IYYI@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA TolQ ExbB proton channel MAG.T2.42_02166 1142394.PSMK_00320 6e-12 78.2 Bacteria exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria COG0848@1,COG0848@2 NA|NA|NA U biopolymer transport protein MAG.T2.42_02168 497964.CfE428DRAFT_3494 1.2e-40 173.7 Bacteria omcN ko:K08999 ko00000 Bacteria COG3880@1,COG3880@2 NA|NA|NA E PFAM UvrB UvrC protein MAG.T2.42_02169 344747.PM8797T_32290 2.2e-61 243.4 Planctomycetes ko:K03086 ko00000,ko03021 Bacteria 2IYCB@203682,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T2.42_02170 1125971.ASJB01000096_gene689 3.5e-59 235.7 Pseudonocardiales csd Bacteria 2I4DJ@201174,4EDZU@85010,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V MAG.T2.42_02171 1142394.PSMK_12700 2.9e-80 307.0 Planctomycetes Bacteria 2IYMX@203682,COG0457@1,COG0457@2 NA|NA|NA O Tetratricopeptide repeat MAG.T2.42_02174 1123389.ATXJ01000001_gene657 2.4e-45 188.7 Deinococcus-Thermus MMAB 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 1WJ8A@1297,COG2096@1,COG2096@2 NA|NA|NA S PFAM Cobalamin adenosyltransferase MAG.T2.42_02175 553217.ENHAE0001_2439 2.7e-71 276.2 Moraxellaceae wcaJ GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 ko:K05946,ko:K21303 ko05111,map05111 ko00000,ko00001,ko01000,ko01003,ko01005 GT26 Bacteria 1MV6W@1224,1RMMN@1236,3NKCB@468,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase MAG.T2.42_02176 1121377.KB906432_gene909 1.4e-101 376.7 Deinococcus-Thermus aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1WKYW@1297,COG0337@1,COG0337@2 NA|NA|NA E 3-dehydroquinate synthase MAG.T2.42_02177 439235.Dalk_2239 4.2e-21 110.5 Deltaproteobacteria fhaB GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K15125,ko:K20276 ko02024,ko05133,map02024,map05133 ko00000,ko00001,ko00536 Bacteria 1N837@1224,2WQFV@28221,42UYE@68525,COG0075@1,COG0075@2,COG3210@1,COG3210@2,COG4733@1,COG4733@2 NA|NA|NA U domain, Protein MAG.T2.42_02178 1142394.PSMK_03170 2.7e-46 191.4 Planctomycetes ko:K07051 ko00000 Bacteria 2IXI8@203682,COG1099@1,COG1099@2 NA|NA|NA S with the TIM-barrel fold MAG.T2.42_02179 2074.JNYD01000046_gene7290 2.4e-45 188.7 Pseudonocardiales kmo GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNR6@201174,4DX5M@85010,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T2.42_02180 269482.Bcep1808_2699 3.5e-45 188.3 Burkholderiaceae kynB GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1K19R@119060,1P8U5@1224,2VHG4@28216,COG1878@1,COG1878@2 NA|NA|NA S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation MAG.T2.42_02181 937777.Deipe_2183 6.6e-58 230.7 Bacteria Bacteria COG2013@1,COG2013@2 NA|NA|NA S Mitochondrial biogenesis AIM24 MAG.T2.42_02182 1163407.UU7_01542 1.9e-42 178.7 Xanthomonadales amnD 3.5.99.5,4.1.1.77 ko:K01617,ko:K15067 ko00362,ko00380,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R03887,R05374 RC00751,RC01015,RC02672 ko00000,ko00001,ko00002,ko01000 Bacteria 1MYEM@1224,1S5CQ@1236,1X6F2@135614,COG0251@1,COG0251@2 NA|NA|NA J translation initiation inhibitor, yjgF family MAG.T2.42_02183 1142394.PSMK_15840 7.2e-75 287.3 Planctomycetes trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2494,iJN746.PP_0422 Bacteria 2IX3M@203682,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family MAG.T2.42_02184 1142394.PSMK_17410 1.6e-09 70.5 Planctomycetes ko:K07052,ko:K09696 ko02010,ko02020,map02010,map02020 M00253 ko00000,ko00001,ko00002,ko02000 3.A.1.115 Bacteria 2J1C8@203682,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T2.42_02185 1254432.SCE1572_37315 9.2e-134 483.4 Myxococcales trpS 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV4T@1224,2WJI2@28221,2YV60@29,42MCV@68525,COG0180@1,COG0180@2 NA|NA|NA J tRNA synthetases class I (W and Y) MAG.T2.42_02186 1142394.PSMK_10300 2e-69 269.6 Planctomycetes xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2IY3V@203682,COG4974@1,COG4974@2 NA|NA|NA D tyrosine recombinase XerC MAG.T2.42_02187 867903.ThesuDRAFT_01952 2.3e-116 426.4 Clostridiales incertae sedis cadA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.3,3.6.3.5 ko:K01534,ko:K12951,ko:K21887 ko00000,ko01000 3.A.3,3.A.3.6 Bacteria 1TQ07@1239,248EH@186801,3WCD7@538999,COG2217@1,COG2217@2 NA|NA|NA P heavy metal-(Cd Co Hg Pb Zn)-translocating P-type ATPase MAG.T2.42_02188 1142394.PSMK_11000 5.3e-71 275.0 Planctomycetes dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K05540 ko00000,ko01000,ko03016 Bacteria 2IYI5@203682,COG0042@1,COG0042@2 NA|NA|NA H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T2.42_02195 1123242.JH636436_gene159 3.8e-12 78.6 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZT4@203682,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.42_02196 1267533.KB906733_gene3472 2.2e-48 201.4 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_02197 755732.Fluta_1390 2.2e-21 111.3 Flavobacteriia 3.4.21.50 ko:K01337 ko00000,ko01000,ko01002 Bacteria 1I21K@117743,4NNHP@976,COG3291@1,COG3291@2,COG3405@1,COG3405@2 NA|NA|NA U Pkd domain containing protein MAG.T2.42_02198 1142394.PSMK_05840 8.6e-96 358.2 Planctomycetes dnaX 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IX1M@203682,COG2812@1,COG2812@2 NA|NA|NA H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity MAG.T2.42_02199 1268072.PSAB_00565 2.6e-08 65.1 Paenibacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,26Y4X@186822,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection MAG.T2.42_02200 247490.KSU1_D0338 6.5e-55 220.7 Planctomycetes recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2IXK5@203682,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO MAG.T2.42_02201 314230.DSM3645_26914 2.8e-58 233.4 Planctomycetes Bacteria 2IWZ3@203682,COG0457@1,COG0457@2 NA|NA|NA S Oxygen tolerance MAG.T2.42_02202 1499967.BAYZ01000152_gene1397 1.3e-10 73.9 unclassified Bacteria Bacteria 2NP5J@2323,COG0457@1,COG0457@2 NA|NA|NA S Oxygen tolerance MAG.T2.42_02203 926569.ANT_23270 6.4e-13 81.3 Bacteria ko:K08978 ko00000,ko02000 2.A.7.2 Bacteria COG2510@1,COG2510@2 NA|NA|NA EG membrane MAG.T2.42_02204 1379698.RBG1_1C00001G1527 3.9e-70 272.7 unclassified Bacteria 3.4.21.66 ko:K08651 ko00000,ko01000,ko01002,ko03110 Bacteria 2NPDC@2323,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 MAG.T2.42_02205 1142394.PSMK_18310 2.4e-157 562.4 Planctomycetes phnV ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 2J51F@203682,COG1178@1,COG1178@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component MAG.T2.42_02206 794903.OPIT5_10485 4.7e-41 176.0 Opitutae 3.4.21.62 ko:K01342,ko:K12287,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko02044,ko03110 Bacteria 3K9SW@414999,46WMI@74201,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_02207 1397528.Q671_04185 6.9e-14 83.2 Oceanospirillales hupB ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1MZ5B@1224,1S8VH@1236,1XKNG@135619,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions MAG.T2.42_02208 1142394.PSMK_31480 1.5e-68 266.5 Planctomycetes Bacteria 2IZKG@203682,COG1052@1,COG1052@2 NA|NA|NA CH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MAG.T2.42_02209 351016.RAZWK3B_13574 2.8e-45 189.9 Alphaproteobacteria Bacteria 1RAWV@1224,2C2XI@1,2U5X3@28211,30D1S@2 NA|NA|NA MAG.T2.42_02210 109760.SPPG_01383T0 1.5e-58 234.6 Fungi Fungi 38DUK@33154,3P0M9@4751,COG2866@1,KOG2650@2759 NA|NA|NA O Allomyces macrogynus ATCC 38327 MAG.T2.42_02211 518766.Rmar_2799 2.5e-26 126.3 Bacteroidetes phuW Bacteria 4NEQ4@976,COG3016@1,COG3016@2 NA|NA|NA S Iron-regulated protein MAG.T2.42_02213 861299.J421_2861 1.3e-67 263.5 Gemmatimonadetes Bacteria 1ZTKD@142182,COG0500@1,COG0640@1,COG0640@2,COG2226@2 NA|NA|NA KQ helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T2.42_02217 1142394.PSMK_15550 7.3e-07 60.8 Planctomycetes ko:K09793 ko00000 Bacteria 2J1KN@203682,COG2839@1,COG2839@2 NA|NA|NA S Protein of unknown function (DUF456) MAG.T2.42_02220 1896.JOAU01000005_gene4782 2.5e-19 102.8 Actinobacteria mqnB GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.4.2.1,3.2.2.26,3.2.2.9 ko:K01243,ko:K03784,ko:K11783 ko00130,ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,ko01230,map00130,map00230,map00240,map00270,map00760,map01100,map01110,map01230 M00034,M00609 R00194,R01401,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R08587,R10244 RC00033,RC00063,RC00122,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNXM@201174,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.42_02221 1303518.CCALI_02306 7.2e-46 190.7 Bacteria Bacteria COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity MAG.T2.42_02223 269800.Tfu_1016 7.9e-105 386.7 Streptosporangiales ctaD GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2GJHX@201174,4EFHC@85012,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B MAG.T2.42_02224 351607.Acel_0958 2.8e-24 118.2 Frankiales ctaF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2D9MJ@1,2IFFM@201174,32TTI@2,4ETA5@85013 NA|NA|NA C Belongs to the cytochrome c oxidase bacterial subunit CtaF family MAG.T2.42_02226 469371.Tbis_1298 5.1e-92 344.7 Pseudonocardiales trpD 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM4G@201174,4DYFX@85010,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) MAG.T2.42_02227 196162.Noca_3132 6.1e-46 190.3 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 2II71@201174,4DQR3@85009,COG0784@1,COG0784@2 NA|NA|NA T cheY-homologous receiver domain MAG.T2.42_02228 1214101.BN159_6284 3.2e-70 271.6 Actinobacteria ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 iJN678.ctaE Bacteria 2GKK8@201174,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase, subunit III MAG.T2.42_02229 1504319.GM45_0765 1.2e-71 276.6 unclassified Actinobacteria (class) qcrC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K00406,ko:K03889 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00151,M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 2GKUB@201174,3UWHN@52018,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III MAG.T2.42_02230 1504319.GM45_0760 6e-103 380.9 unclassified Actinobacteria (class) qcrA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03890,ko:K15878 ko00190,ko01100,map00190,map01100 M00151 ko00000,ko00001,ko00002 iAF987.Gmet_0538 Bacteria 2GIX6@201174,3UWCF@52018,COG0723@1,COG0723@2 NA|NA|NA C Rieske [2Fe-2S] domain MAG.T2.42_02231 644107.SL1157_A0082 1.1e-116 427.2 Ruegeria gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 1MUQ1@1224,2TS6R@28211,4NAWY@97050,COG0696@1,COG0696@2 NA|NA|NA F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate MAG.T2.42_02232 272943.RSP_0932 6.1e-59 233.8 Rhodobacter ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1FBI3@1060,1MU39@1224,2TRW2@28211,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T2.42_02233 1207063.P24_14519 1.5e-53 216.9 Rhodospirillales yphC 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 iECW_1372.ECW_m2771,iWFL_1372.ECW_m2771 Bacteria 1QTU5@1224,2JQP9@204441,2TW9Q@28211,COG1063@1,COG1063@2 NA|NA|NA E Alanine dehydrogenase/PNT, C-terminal domain MAG.T2.42_02238 1142394.PSMK_07340 6.3e-11 75.9 Planctomycetes Bacteria 2FEU1@1,2J3WI@203682,346SY@2 NA|NA|NA MAG.T2.42_02239 1142394.PSMK_01780 3.1e-53 216.1 Planctomycetes lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 Bacteria 2IXXN@203682,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.42_02241 521674.Plim_2306 2.6e-112 412.1 Planctomycetes livJ ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IYKT@203682,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region MAG.T2.42_02242 521674.Plim_2307 1.4e-93 349.7 Planctomycetes livH ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IWS7@203682,COG0559@1,COG0559@2 NA|NA|NA E Branched-chain amino acid transport system / permease component MAG.T2.42_02243 521674.Plim_2308 2.4e-84 319.3 Planctomycetes ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IYM8@203682,COG4177@1,COG4177@2 NA|NA|NA E Branched-chain amino acid transport system / permease component MAG.T2.42_02244 404589.Anae109_4413 7e-81 307.4 Myxococcales livG ko:K01995 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1MUTY@1224,2WJIS@28221,2YWX6@29,42NMG@68525,COG0411@1,COG0411@2 NA|NA|NA E amino acid ABC transporter, ATP-binding protein MAG.T2.42_02245 521674.Plim_2310 9.1e-82 310.1 Planctomycetes livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2IYQW@203682,COG0410@1,COG0410@2 NA|NA|NA E ABC transporter MAG.T2.42_02247 1142394.PSMK_02410 1.2e-30 139.8 Planctomycetes ko:K06940 ko00000 Bacteria 2IZM1@203682,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T2.42_02248 46429.BV95_02237 9.2e-57 226.9 Sphingomonadales 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1MU7T@1224,2K3CC@204457,2TRVY@28211,COG0726@1,COG0726@2,COG2931@1,COG2931@2 NA|NA|NA GQ Peptidase M10 serralysin C terminal MAG.T2.42_02249 886293.Sinac_2714 2.5e-122 445.7 Planctomycetes Bacteria 2IXFW@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins MAG.T2.42_02250 886293.Sinac_1196 6.7e-48 198.4 Planctomycetes rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2IY8T@203682,COG0349@1,COG0349@2 NA|NA|NA J COG0349 Ribonuclease D MAG.T2.42_02251 595460.RRSWK_05050 5.7e-73 282.0 Bacteria Bacteria COG1409@1,COG1409@2 NA|NA|NA S acid phosphatase activity MAG.T2.42_02252 521674.Plim_1880 1.7e-101 377.1 Planctomycetes lppC GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06910 ko00000 Bacteria 2IX7Y@203682,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein MAG.T2.42_02253 595460.RRSWK_05050 9.8e-81 307.8 Bacteria Bacteria COG1409@1,COG1409@2 NA|NA|NA S acid phosphatase activity MAG.T2.42_02254 102125.Xen7305DRAFT_00048450 1.3e-24 121.3 Pleurocapsales Bacteria 1G2CB@1117,3VM5E@52604,COG2133@1,COG2133@2,COG2931@1,COG2931@2 NA|NA|NA GQ Glucose Sorbosone dehydrogenase MAG.T2.42_02256 448385.sce0270 1.5e-14 85.5 Myxococcales cas2 ko:K09951 ko00000,ko02048 Bacteria 1N27I@1224,2WSM3@28221,2Z28E@29,42Y24@68525,COG1343@1,COG1343@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette MAG.T2.42_02257 502025.Hoch_4852 3.6e-146 525.4 Myxococcales cas1 GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0030145,GO:0034641,GO:0034655,GO:0035312,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045145,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.12.1 ko:K07464,ko:K15342 ko00000,ko01000,ko02048,ko03400 Bacteria 1MUKK@1224,2X2YF@28221,2YZFB@29,43A4J@68525,COG1468@1,COG1468@2,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette MAG.T2.42_02258 765912.Thimo_1277 3.1e-21 109.4 Proteobacteria Bacteria 1NDIC@1224,2C1S9@1,32R0M@2 NA|NA|NA MAG.T2.42_02259 575540.Isop_1832 3e-246 858.6 Planctomycetes ko:K07012 ko00000,ko01000,ko02048 Bacteria 2IXEG@203682,COG1203@1,COG1203@2 NA|NA|NA L CRISPR-associated helicase, Cas3 MAG.T2.42_02260 575540.Isop_1833 4.6e-164 584.7 Planctomycetes ko:K19132 ko00000,ko02048 Bacteria 2DBH6@1,2J2FW@203682,2Z97W@2 NA|NA|NA S CRISPR-associated protein, GSU0054 family (Cas_GSU0054) MAG.T2.42_02261 575540.Isop_1834 1.6e-137 496.1 Planctomycetes csb1 ko:K19131 ko00000,ko02048 Bacteria 28KC2@1,2J1B0@203682,2Z9Z2@2 NA|NA|NA S CRISPR-associated protein GSU0053 (Cas_GSU0053) MAG.T2.42_02265 118173.KB235914_gene4149 3.1e-68 266.2 Cyanobacteria Bacteria 1G1UY@1117,COG0457@1,COG0457@2 NA|NA|NA S Alternative locus ID MAG.T2.42_02266 861299.J421_3883 0.0 1159.4 Bacteria cobN 6.6.1.2 ko:K02230 ko00860,ko01100,map00860,map01100 R05227 RC02000 ko00000,ko00001,ko01000 Bacteria COG1429@1,COG1429@2 NA|NA|NA H ligase activity, forming nitrogen-metal bonds MAG.T2.42_02267 443144.GM21_2219 8.4e-87 327.4 Deltaproteobacteria glk 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFI@1224,2WN6N@28221,42QTP@68525,COG0837@1,COG0837@2 NA|NA|NA G Belongs to the bacterial glucokinase family MAG.T2.42_02268 631362.Thi970DRAFT_03258 3.9e-124 452.6 Chromatiales Bacteria 1N7SK@1224,1RNC8@1236,1WXBI@135613,COG1297@1,COG1297@2 NA|NA|NA S oligopeptide transporter MAG.T2.42_02269 766499.C357_03565 3.4e-39 169.1 Alphaproteobacteria Bacteria 1P2CE@1224,2UVHQ@28211,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family MAG.T2.42_02271 1142394.PSMK_26530 2e-42 179.5 Planctomycetes lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 Bacteria 2J09X@203682,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate MAG.T2.42_02272 1195236.CTER_3077 7e-56 224.2 Ruminococcaceae dedA1 ko:K03975 ko00000 Bacteria 1UZ4P@1239,24FU4@186801,3WN8K@541000,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T2.42_02273 756272.Plabr_1906 3.9e-23 115.5 Planctomycetes Bacteria 2J3MF@203682,COG4978@1,COG4978@2 NA|NA|NA KT PFAM SOUL heme-binding protein MAG.T2.42_02274 861299.J421_1936 5.7e-211 740.7 Gemmatimonadetes kup ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1ZTCK@142182,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell MAG.T2.42_02275 324602.Caur_0299 1e-20 108.6 Chloroflexia tek ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 2GB82@200795,377IZ@32061,COG5295@1,COG5295@2 NA|NA|NA UW Hep Hag repeat protein MAG.T2.42_02277 525257.HMPREF0204_12361 8.5e-32 145.2 Chryseobacterium CP_1075 Bacteria 1IIHW@117743,3ZQ5Q@59732,4NRK6@976,COG2273@1,COG2273@2,COG5563@1,COG5563@2 NA|NA|NA G endonuclease I MAG.T2.42_02278 66373.JOFQ01000009_gene680 1.5e-11 75.9 Actinobacteria ko:K04749 ko00000,ko03021 Bacteria 2IH0A@201174,COG1366@1,COG1366@2 NA|NA|NA T STAS domain MAG.T2.42_02279 497964.CfE428DRAFT_6676 1.4e-51 210.3 Verrucomicrobia nhaR ko:K03717 ko00000,ko03000 Bacteria 46TZU@74201,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain MAG.T2.42_02280 390989.JOEG01000001_gene5234 3.3e-29 136.0 Micromonosporales otsB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K01087,ko:K16055 ko00500,ko01100,map00500,map01100 R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT20 iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495 Bacteria 2GJAD@201174,4D9PM@85008,COG1877@1,COG1877@2,COG3387@1,COG3387@2 NA|NA|NA G Trehalose-phosphatase MAG.T2.42_02281 794903.OPIT5_22945 9e-71 274.6 Opitutae clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 3K8QQ@414999,46U0T@74201,COG0740@1,COG0740@2 NA|NA|NA OU Clp protease MAG.T2.42_02282 264732.Moth_2025 5.1e-125 454.9 Thermoanaerobacterales xylB 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 iYO844.BSU17610 Bacteria 1TQ1I@1239,247NR@186801,42EP0@68295,COG1070@1,COG1070@2 NA|NA|NA H PFAM carbohydrate kinase MAG.T2.42_02283 264732.Moth_2026 2.2e-125 455.7 Thermoanaerobacterales xylA_2 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 Bacteria 1UD8H@1239,24HDU@186801,42FRC@68295,COG4952@1,COG4952@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T2.42_02284 525257.HMPREF0204_12135 2.2e-12 80.1 Chryseobacterium Bacteria 1IM33@117743,2A7BD@1,30W82@2,3ZSKS@59732,4PGK4@976 NA|NA|NA S Hyaluronidase MAG.T2.42_02285 1267533.KB906733_gene3472 3.8e-86 326.2 Acidobacteria Bacteria 3Y67Y@57723,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_02286 379066.GAU_3840 2.1e-44 185.7 Gemmatimonadetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1ZV2F@142182,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor MAG.T2.42_02287 452637.Oter_0261 2.2e-15 89.7 Verrucomicrobia Bacteria 2ECN9@1,336K5@2,46T7K@74201 NA|NA|NA MAG.T2.42_02288 926550.CLDAP_29660 3.8e-88 332.0 Bacteria Bacteria COG1748@1,COG1748@2 NA|NA|NA E saccharopine dehydrogenase activity MAG.T2.42_02289 1142394.PSMK_17220 1e-56 226.5 Planctomycetes ndhJ GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0050136,GO:0055114,GO:0071944 1.6.5.3 ko:K00332,ko:K05581,ko:K13378 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iJN678.ndhJ Bacteria 2IZSU@203682,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.42_02290 595460.RRSWK_03901 1.5e-08 68.6 Bacteria 3.2.1.51 ko:K15923,ko:K20276 ko00511,ko02024,map00511,map02024 ko00000,ko00001,ko01000 GH95 Bacteria COG0689@1,COG0689@2,COG1572@1,COG1572@2,COG3210@1,COG3210@2 NA|NA|NA NU bacterial-type flagellum-dependent cell motility MAG.T2.42_02291 344747.PM8797T_31223 1.4e-29 136.3 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2J3FS@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog MAG.T2.42_02292 1123257.AUFV01000005_gene1417 3.3e-45 190.7 Xanthomonadales Bacteria 1MV1P@1224,1RR36@1236,1XCDH@135614,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T2.42_02293 1123508.JH636439_gene332 1.4e-10 74.7 Planctomycetes ko:K13735 ko05100,map05100 ko00000,ko00001 Bacteria 2J3BU@203682,COG2373@1,COG2373@2,COG2931@1,COG2931@2,COG3209@1,COG3209@2 NA|NA|NA Q amine dehydrogenase activity MAG.T2.42_02294 1089550.ATTH01000001_gene1271 2.1e-53 216.1 Bacteroidetes Order II. Incertae sedis ytnP Bacteria 1FJ3N@1100069,4NE98@976,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T2.42_02295 756272.Plabr_2248 3.7e-146 525.0 Planctomycetes wbpA 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 Bacteria 2IXVX@203682,COG0677@1,COG0677@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T2.42_02298 502025.Hoch_6539 7.6e-33 149.4 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_02299 1125863.JAFN01000001_gene3571 4.1e-23 114.8 Deltaproteobacteria sigX ko:K03088 ko00000,ko03021 Bacteria 1RHKM@1224,2X6BZ@28221,43AXT@68525,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.42_02301 373994.Riv7116_5696 5.7e-89 335.1 Nostocales ko:K03929 ko00000,ko01000 CE10 Bacteria 1G5FC@1117,1HQSJ@1161,COG2931@1,COG2931@2,COG4222@1,COG4222@2 NA|NA|NA Q CHRD domain MAG.T2.42_02302 313606.M23134_00707 2.4e-33 149.4 Cytophagia Bacteria 32TPV@2,47VU6@768503,4NMI6@976,KOG3539@1 NA|NA|NA S Spondin_N MAG.T2.42_02303 1121957.ATVL01000014_gene1459 9.6e-07 61.6 Cytophagia Bacteria 47VHU@768503,4PHUI@976,COG5563@1,COG5563@2 NA|NA|NA MAG.T2.42_02304 1210884.HG799469_gene14124 5.3e-91 341.3 Planctomycetes Bacteria 2IYWN@203682,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T2.42_02305 886293.Sinac_6370 2.5e-123 449.1 Planctomycetes Bacteria 2IX87@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) MAG.T2.42_02306 521674.Plim_0287 1.2e-126 461.1 Planctomycetes Bacteria 2IXB2@203682,COG0551@1,COG0551@2 NA|NA|NA L Ca-dependent carbohydrate-binding module xylan-binding MAG.T2.42_02312 457570.Nther_0354 1.6e-09 70.5 Bacteria 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process MAG.T2.42_02316 1123508.JH636451_gene5931 6.5e-20 105.5 Planctomycetes Bacteria 2EXT5@1,2J1YC@203682,33R2E@2 NA|NA|NA MAG.T2.42_02319 1142394.PSMK_03060 1.9e-58 233.0 Planctomycetes Bacteria 2IZFB@203682,COG4783@1,COG4783@2 NA|NA|NA S Zn-dependent protease contains TPR repeats MAG.T2.42_02320 1142394.PSMK_31090 3.3e-58 232.3 Planctomycetes ko:K07045 ko00000 Bacteria 2IXTD@203682,COG2159@1,COG2159@2 NA|NA|NA S TIM-barrel fold MAG.T2.42_02322 634956.Geoth_2622 3.2e-54 218.8 Geobacillus ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TR9P@1239,1WE5D@129337,4HAV5@91061,COG1692@1,COG1692@2 NA|NA|NA S YmdB-like protein MAG.T2.42_02324 1142394.PSMK_04800 5.6e-39 168.3 Planctomycetes ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 2J1IS@203682,COG1360@1,COG1360@2 NA|NA|NA N Flagellar motor protein MAG.T2.42_02325 886293.Sinac_0081 7.9e-173 613.2 Planctomycetes Bacteria 2IXU6@203682,COG4447@1,COG4447@2 NA|NA|NA L cellulose binding MAG.T2.42_02326 240015.ACP_1949 1.3e-30 139.0 Acidobacteriia 2.7.7.80,2.8.1.11 ko:K03636,ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 2JJVU@204432,3Y5J3@57723,COG1977@1,COG1977@2 NA|NA|NA H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin MAG.T2.42_02327 1142394.PSMK_02450 3.9e-59 235.7 Planctomycetes ssnA 3.5.4.40 ko:K20810 ko00130,ko01110,map00130,map01110 R10695 RC00477 ko00000,ko00001,ko01000 Bacteria 2IYVP@203682,COG0402@1,COG0402@2 NA|NA|NA F COG0402 Cytosine deaminase and related metal-dependent MAG.T2.42_02331 1142394.PSMK_13440 1.1e-71 277.7 Planctomycetes pliT Bacteria 2IXF3@203682,COG4956@1,COG4956@2 NA|NA|NA S Integral membrane protein (PIN domain superfamily) MAG.T2.42_02333 398512.JQKC01000004_gene5235 1.2e-27 130.6 Ruminococcaceae algU ko:K03088 ko00000,ko03021 Bacteria 1TS3M@1239,24IW2@186801,3WIW4@541000,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T2.42_02334 1142394.PSMK_15990 2.9e-148 531.9 Planctomycetes purB 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXU4@203682,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily MAG.T2.42_02335 1142394.PSMK_06800 1.8e-23 115.9 Planctomycetes pncA Bacteria 2J0BP@203682,COG1335@1,COG1335@2 NA|NA|NA Q isochorismatase hydrolase MAG.T2.42_02336 247490.KSU1_C1680 5.4e-30 137.5 Planctomycetes fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 2IZNA@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) MAG.T2.42_02337 1142394.PSMK_06150 4.7e-63 248.4 Planctomycetes manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZ3A@203682,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase MAG.T2.42_02338 1047013.AQSP01000144_gene927 1.5e-142 513.8 unclassified Bacteria ko:K09955 ko00000 Bacteria 2NNW0@2323,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 MAG.T2.42_02339 439235.Dalk_2235 3.2e-81 308.9 Bacteria Bacteria COG0863@1,COG0863@2 NA|NA|NA L N-4 methylation of cytosine MAG.T2.42_02341 471852.Tcur_4487 9.8e-51 207.2 Streptosporangiales panC GO:0000166,GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0019482,GO:0019752,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033317,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042133,GO:0042364,GO:0042398,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3602c Bacteria 2GJEQ@201174,4EG66@85012,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate MAG.T2.42_02342 1461693.ATO10_09273 3.3e-75 289.3 Proteobacteria Bacteria 1R7B3@1224,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T2.42_02343 1461693.ATO10_09278 1.3e-19 104.0 Proteobacteria Bacteria 1N4NZ@1224,2E03A@1,32VS4@2 NA|NA|NA MAG.T2.42_02344 292564.Cyagr_1794 1.1e-53 216.9 Bacteria ko:K03668,ko:K09914 ko00000 Bacteria COG3187@1,COG3187@2 NA|NA|NA O response to heat MAG.T2.42_02345 926560.KE387027_gene1021 1e-106 393.7 Deinococcus-Thermus Bacteria 1WM7S@1297,2DB7V@1,2Z7NX@2 NA|NA|NA MAG.T2.42_02346 1042375.AFPL01000022_gene2676 2.4e-16 94.4 Gammaproteobacteria yapH ko:K12685,ko:K19231 ko00000,ko01000,ko02000,ko02044 1.B.12,1.B.12.5.1,1.B.12.5.3 Bacteria 1MU92@1224,1SZHZ@1236,COG3210@1,COG3210@2,COG4625@1,COG4625@2 NA|NA|NA U Autotransporter beta-domain MAG.T2.42_02348 1121957.ATVL01000006_gene2766 1.7e-10 73.9 Cytophagia Bacteria 47R0V@768503,4NJHV@976,COG3291@1,COG3291@2 NA|NA|NA S Fibronectin type 3 domain MAG.T2.42_02350 1340493.JNIF01000003_gene1637 1.1e-139 503.1 Acidobacteria yahK GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.1 ko:K13953,ko:K13979 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 3Y33B@57723,COG1064@1,COG1064@2 NA|NA|NA S PFAM Alcohol dehydrogenase MAG.T2.42_02351 1408473.JHXO01000015_gene1897 8e-09 68.6 Bacteria Bacteria COG3291@1,COG3291@2,COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_02352 1168059.KB899087_gene685 1.8e-65 255.4 Xanthobacteraceae Bacteria 1Q354@1224,2VA5H@28211,3F1SB@335928,COG0662@1,COG0662@2 NA|NA|NA G Cupin 2, conserved barrel domain protein MAG.T2.42_02355 110319.CF8_2807 1.8e-49 203.0 Propionibacteriales truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2GJZK@201174,4DPKY@85009,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs MAG.T2.42_02356 1239962.C943_00050 2.5e-100 373.2 Cytophagia 3.4.17.21 ko:K01301 ko00000,ko01000,ko01002 Bacteria 47MK3@768503,4NI5W@976,COG2234@1,COG2234@2 NA|NA|NA S glutamate carboxypeptidase MAG.T2.42_02357 479434.Sthe_2758 2.6e-92 345.9 Chloroflexi stsC Bacteria 2G5QG@200795,COG0399@1,COG0399@2 NA|NA|NA E aromatic amino acid beta-eliminating lyase threonine aldolase MAG.T2.42_02358 1379698.RBG1_1C00001G1263 8.3e-70 271.6 unclassified Bacteria aprN Bacteria 2NNSK@2323,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T2.42_02359 595460.RRSWK_03591 6.1e-20 104.4 Planctomycetes Bacteria 2J0TW@203682,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family MAG.T2.42_02360 1123237.Salmuc_00962 8.4e-19 100.5 Alphaproteobacteria grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1RH8T@1224,2U5V2@28211,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MAG.T2.42_02361 1142394.PSMK_19850 6.2e-101 374.4 Planctomycetes dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 2IXQJ@203682,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T2.42_02362 1142394.PSMK_19840 1.5e-45 189.1 Planctomycetes groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2IXJW@203682,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T2.42_02363 1122223.KB890696_gene156 8.1e-35 153.3 Deinococcus-Thermus fur ko:K03711,ko:K22297 ko00000,ko03000 Bacteria 1WJYT@1297,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family MAG.T2.42_02364 644282.Deba_0604 4.2e-60 238.4 Deltaproteobacteria znuB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K02075,ko:K09816,ko:K19976 ko02010,map02010 M00242,M00244,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1MVC2@1224,2WJAM@28221,42MYM@68525,COG1108@1,COG1108@2 NA|NA|NA P PFAM ABC-3 protein MAG.T2.42_02365 644282.Deba_0603 2.1e-58 232.6 Deltaproteobacteria znuC ko:K09817 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 1MUDW@1224,2WKMZ@28221,42NI8@68525,COG1121@1,COG1121@2 NA|NA|NA P PFAM ABC transporter MAG.T2.42_02366 1049564.TevJSym_az00390 1.1e-46 194.1 unclassified Gammaproteobacteria znuA 1.6.5.3 ko:K00341,ko:K02077,ko:K09815 ko00190,ko01100,ko02010,map00190,map01100,map02010 M00144,M00242,M00244 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.D.1 Bacteria 1JC36@118884,1MVW9@1224,1T1Q3@1236,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic MAG.T2.42_02367 886293.Sinac_4605 9.1e-111 407.1 Bacteria Bacteria COG5434@1,COG5434@2 NA|NA|NA M polygalacturonase activity MAG.T2.42_02368 1242864.D187_000949 8.7e-33 147.1 Deltaproteobacteria hutD ko:K09975 ko00000 Bacteria 1RH9G@1224,2WX79@28221,43245@68525,COG3758@1,COG3758@2 NA|NA|NA S HutD MAG.T2.42_02369 448385.sce3623 1.3e-92 348.6 Myxococcales 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWJA@1224,2WMH1@28221,2YU5N@29,42P8D@68525,COG0775@1,COG0775@2,COG2319@1,COG2319@2,COG5635@1,COG5635@2 NA|NA|NA T WD-40 repeat MAG.T2.42_02370 273677.BW34_00361 5.9e-18 97.8 Microbacteriaceae aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GRFW@201174,4FP8M@85023,COG0703@1,COG0703@2 NA|NA|NA E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate MAG.T2.42_02372 886293.Sinac_1725 9.4e-58 230.3 Planctomycetes rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2IYW1@203682,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism MAG.T2.42_02373 1142394.PSMK_30500 1.6e-221 775.4 Planctomycetes atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2IY7P@203682,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits MAG.T2.42_02375 1142394.PSMK_03230 6.1e-30 137.1 Planctomycetes nfuA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K07400,ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2J01F@203682,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T2.42_02376 1500894.JQNN01000001_gene2151 3.5e-49 201.1 Oxalobacteraceae iscU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055 Bacteria 1RD5K@1224,2VQ2I@28216,474BF@75682,COG0822@1,COG0822@2 NA|NA|NA C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters MAG.T2.42_02377 1382359.JIAL01000001_gene821 4e-144 518.1 Acidobacteriia iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 iPC815.YPO2896,iYL1228.KPN_02862 Bacteria 2JI55@204432,3Y3CG@57723,COG1104@1,COG1104@2 NA|NA|NA E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins MAG.T2.42_02378 448385.sce0519 6.5e-10 72.0 Myxococcales Bacteria 1R0BE@1224,2X817@28221,2Z05E@29,43CTP@68525,COG3391@1,COG3391@2,COG3591@1,COG3591@2 NA|NA|NA E Stigma-specific protein, Stig1 MAG.T2.42_02379 1122179.KB890451_gene4532 1.7e-13 84.0 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T2.42_02381 756272.Plabr_4524 5.8e-53 214.9 Bacteria ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T2.42_02382 1142394.PSMK_21310 1.9e-39 169.1 Planctomycetes coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZM2@203682,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate MAG.T2.42_02383 1142394.PSMK_24100 8.7e-35 153.7 Planctomycetes 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IZWX@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) MAG.T2.42_02384 1142394.PSMK_24110 5.5e-31 140.6 Planctomycetes acpP 2.7.9.2 ko:K01007,ko:K02078 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2J04I@203682,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T2.42_02385 886293.Sinac_6209 2.1e-17 95.5 Planctomycetes 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2J09I@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) MAG.T2.42_02386 867903.ThesuDRAFT_01380 3.5e-91 341.7 Clostridia ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,24C3R@186801,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily MAG.T2.42_02388 5786.XP_003285756.1 1.4e-111 409.5 Amoebozoa GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046073,GO:0046385,GO:0046483,GO:0050797,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 R06613 RC00022,RC00332 ko00000,ko00001,ko01000 Eukaryota 2SRAF@2759,3XEH7@554915,COG1351@1 NA|NA|NA H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant MAG.T2.42_02389 1242864.D187_003211 4.7e-19 101.7 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T2.42_02393 477974.Daud_1871 2.7e-28 132.1 Peptococcaceae hit GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 Bacteria 1V5CH@1239,24HFR@186801,266WR@186807,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding MAG.T2.42_02395 1142394.PSMK_28130 7e-64 251.5 Bacteria Bacteria 2DRTQ@1,32URN@2 NA|NA|NA MAG.T2.42_02396 1185876.BN8_03965 1e-24 119.4 Cytophagia ykkD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K11741,ko:K18925 M00712 ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.5 Bacteria 47R8W@768503,4NQ4U@976,COG2076@1,COG2076@2 NA|NA|NA P PFAM small multidrug resistance protein MAG.T2.42_02398 306281.AJLK01000109_gene3201 6.7e-124 451.1 Stigonemataceae hmgA 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 Bacteria 1G3C7@1117,1JJJK@1189,COG3508@1,COG3508@2 NA|NA|NA Q homogentisate 1,2-dioxygenase MAG.T2.42_02399 1111730.ATTM01000003_gene582 2.3e-109 402.5 Flavobacterium hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1HWZ3@117743,2NT3U@237,4NFI7@976,COG3185@1,COG3185@2 NA|NA|NA E 4-hydroxyphenylpyruvate dioxygenase MAG.T2.42_02400 247490.KSU1_C0318 1.2e-46 193.0 Planctomycetes apt 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 2IZ9H@203682,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis MAG.T2.42_02401 1142394.PSMK_16420 1.2e-36 159.1 Planctomycetes groES ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IZTF@203682,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T2.42_02402 1142394.PSMK_13920 6.2e-74 285.0 Planctomycetes aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXRF@203682,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate MAG.T2.42_02403 1142394.PSMK_06310 3.4e-85 322.8 Planctomycetes msbA ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2IXKY@203682,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system ATPase and permease MAG.T2.42_02405 987059.RBXJA2T_12417 4.7e-12 79.0 unclassified Burkholderiales ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1KK88@119065,1MWVF@1224,2VJ7T@28216,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein MAG.T2.42_02406 1142394.PSMK_21000 3.1e-38 166.0 Planctomycetes ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2J03D@203682,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily MAG.T2.42_02407 1142394.PSMK_18070 3.9e-93 348.6 Planctomycetes dinB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 2IZ2I@203682,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII MAG.T2.42_02410 1142394.PSMK_00130 1.5e-50 206.8 Planctomycetes ubiA 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IX4Z@203682,COG0382@1,COG0382@2 NA|NA|NA H COG0382 4-hydroxybenzoate polyprenyltransferase and related MAG.T2.42_02412 1142394.PSMK_30760 2.1e-136 492.7 Planctomycetes ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2IXSC@203682,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY MAG.T2.42_02413 926564.KI911678_gene5264 3.4e-12 80.9 Promicromonosporaceae bpr GO:0005575,GO:0005576 3.2.1.4 ko:K01179,ko:K13276 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01002,ko03110 GH5,GH9 Bacteria 2HQIW@201174,4F5H7@85017,COG1404@1,COG1404@2,COG3055@1,COG3055@2 NA|NA|NA O Subtilase family MAG.T2.42_02414 472759.Nhal_2852 1.3e-33 151.4 Bacteria tqsA ko:K03548 ko00000,ko02000 2.A.86.1 Bacteria COG0628@1,COG0628@2 NA|NA|NA D permease MAG.T2.42_02415 1142394.PSMK_01480 3.1e-22 112.1 Planctomycetes Bacteria 2E5IJ@1,2J0P5@203682,3309Y@2 NA|NA|NA MAG.T2.42_02416 10160.XP_004649037.1 1.7e-33 149.8 Rodentia MPG GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0031974,GO:0031981,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045007,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Mammalia 35CEZ@314146,39RQW@33154,3BA2R@33208,3D02F@33213,3JFKA@40674,488EB@7711,4900A@7742,4Q45E@9989,COG2094@1,COG5272@1,KOG0001@2759,KOG4486@2759 NA|NA|NA L DNA-7-methylguanine glycosylase activity MAG.T2.42_02419 1123226.KB899311_gene1786 6.6e-22 110.9 Paenibacillaceae sigW ko:K03088 ko00000,ko03021 Bacteria 1TS3M@1239,26TDT@186822,4HC17@91061,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T2.42_02422 530564.Psta_1989 9.8e-27 127.5 Planctomycetes ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2J2RX@203682,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family MAG.T2.42_02423 1449350.OCH239_10300 2.9e-11 75.1 Roseivivax ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 1N9Y7@1224,2UFRE@28211,4KNWN@93682,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR MAG.T2.42_02425 305900.GV64_22855 2.6e-13 82.8 Oceanospirillales Bacteria 1MU7T@1224,1RNK8@1236,1XRVR@135619,COG0726@1,COG0726@2,COG1361@1,COG1361@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2,COG3291@1,COG3291@2,COG3533@1,COG3533@2,COG4733@1,COG4733@2,COG5434@1,COG5434@2 NA|NA|NA MQ Dystroglycan-type cadherin-like domains. MAG.T2.42_02426 880073.Calab_1972 3.9e-30 139.0 unclassified Bacteria fkpA 5.2.1.8 ko:K01802,ko:K03772,ko:K09568 ko00000,ko01000,ko03110 Bacteria 2NPVS@2323,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans isomerase MAG.T2.42_02428 297246.lpp2955 5e-26 124.8 Gammaproteobacteria Bacteria 1N20C@1224,1SIXC@1236,2DF6E@1,32U4S@2 NA|NA|NA MAG.T2.42_02429 102129.Lepto7375DRAFT_0245 2.4e-54 219.5 Oscillatoriales tnp Bacteria 1G4RX@1117,1HHM0@1150,COG3547@1,COG3547@2 NA|NA|NA L PFAM Transposase IS116 IS110 IS902 family MAG.T2.42_02433 402777.KB235904_gene3575 3.1e-43 182.6 Oscillatoriales Bacteria 1GQVR@1117,1HI2T@1150,COG2931@1,COG2931@2 NA|NA|NA Q Domain of unknown function (DUF4394) MAG.T2.42_02435 1142394.PSMK_01110 7.9e-94 350.9 Planctomycetes splB 4.1.99.14 ko:K03716 ko00000,ko01000 Bacteria 2IX0U@203682,COG1533@1,COG1533@2 NA|NA|NA L Radical SAM MAG.T2.42_02437 1192759.AKIB01000028_gene2028 6.3e-21 110.2 Alphaproteobacteria nucA ko:K01173,ko:K07004,ko:K14274 ko00040,ko04210,map00040,map04210 R02427 RC00713 ko00000,ko00001,ko01000,ko03029 Bacteria 1MU7T@1224,2UHRC@28211,COG1572@1,COG1572@2,COG1864@1,COG1864@2,COG2931@1,COG2931@2,COG3209@1,COG3209@2,COG3210@1,COG3210@2,COG3386@1,COG3386@2,COG3391@1,COG3391@2,COG5276@1,COG5276@2 NA|NA|NA FGMQ CARDB MAG.T2.42_02440 379066.GAU_0291 1.6e-15 91.3 Gemmatimonadetes Bacteria 1ZT0C@142182,29YN3@1,30KHK@2 NA|NA|NA S Putative ABC exporter MAG.T2.42_02441 243090.RB1310 1.1e-67 263.5 Planctomycetes ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IXVN@203682,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase component MAG.T2.42_02442 344747.PM8797T_16353 3.6e-196 691.4 Planctomycetes GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IXJD@203682,COG4867@1,COG4867@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.42_02444 314230.DSM3645_18291 2e-200 705.3 Planctomycetes chlI 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 R03877 RC01012 ko00000,ko00001,ko01000 iNJ661.Rv0958 Bacteria 2IXX1@203682,COG1239@1,COG1239@2 NA|NA|NA H COG1239 Mg-chelatase subunit ChlI MAG.T2.42_02445 41431.PCC8801_0648 1.8e-77 296.6 Cyanothece corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1G1AG@1117,3KH5P@43988,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions MAG.T2.42_02446 519989.ECTPHS_04493 1.1e-152 547.0 Chromatiales sulP GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 1MVWV@1224,1RMCN@1236,1WX2K@135613,COG0659@1,COG0659@2 NA|NA|NA P sulphate transporter MAG.T2.42_02447 794903.OPIT5_30315 3.4e-20 104.8 Bacteria ko:K18831 ko00000,ko02048,ko03000 Bacteria COG5499@1,COG5499@2 NA|NA|NA K transcription regulator containing HTH domain MAG.T2.42_02450 1288494.EBAPG3_9640 3.4e-144 518.5 Nitrosomonadales MA20_16020 2.6.1.11,2.6.1.13,2.6.1.17,2.6.1.82 ko:K00819,ko:K00821,ko:K09251 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R01155,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1R6U9@1224,2VR1P@28216,371Z3@32003,COG4992@1,COG4992@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T2.42_02452 926550.CLDAP_19500 1.9e-36 160.6 Bacteria 3.1.4.46 ko:K01126,ko:K21449 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000,ko02000 1.B.40.2 Bacteria COG0584@1,COG0584@2,COG0823@1,COG0823@2,COG3210@1,COG3210@2,COG4886@1,COG4886@2 NA|NA|NA S regulation of response to stimulus MAG.T2.42_02453 1379698.RBG1_1C00001G1263 1e-59 238.0 unclassified Bacteria aprN Bacteria 2NNSK@2323,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T2.42_02454 1089550.ATTH01000002_gene11 2.4e-135 489.2 Bacteroidetes Order II. Incertae sedis baeB 3.1.2.6,3.4.21.102 ko:K01069,ko:K03797 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000,ko01002 Bacteria 1FJ2U@1100069,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T2.42_02455 1121378.KB899745_gene3732 2.2e-50 206.1 Deinococcus-Thermus ko:K07090 ko00000 Bacteria 1WIAC@1297,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein MAG.T2.42_02457 1236959.BAMT01000005_gene219 1e-09 71.6 Proteobacteria Bacteria 1P1FQ@1224,COG3055@1,COG3055@2 NA|NA|NA S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T2.42_02458 1142394.PSMK_07060 2.2e-34 152.9 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.42_02460 497964.CfE428DRAFT_5133 5.1e-147 528.1 Verrucomicrobia pepF ko:K08602 ko00000,ko01000,ko01002 Bacteria 46UYB@74201,COG1164@1,COG1164@2 NA|NA|NA E Peptidase family M3 MAG.T2.42_02463 1142394.PSMK_27400 1.9e-61 242.3 Planctomycetes Bacteria 2IY82@203682,COG0745@1,COG0745@2 NA|NA|NA T response regulator receiver MAG.T2.42_02465 439235.Dalk_1425 3.6e-62 245.0 Desulfobacterales Bacteria 1MY2Z@1224,2MJ7C@213118,2WJPD@28221,42MP1@68525,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver MAG.T2.42_02466 338963.Pcar_0654 5e-76 292.4 Desulfuromonadales phoR 2.7.13.3 ko:K02484,ko:K07636,ko:K07768 ko02020,map02020 M00434,M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWF3@1224,2WJGX@28221,42NB5@68525,43SD2@69541,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain MAG.T2.42_02468 247490.KSU1_B0329 4.2e-114 417.9 Planctomycetes pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2IYX0@203682,COG0226@1,COG0226@2 NA|NA|NA P COG0226 ABC-type phosphate transport system periplasmic MAG.T2.42_02469 313628.LNTAR_17353 2.8e-121 443.0 Bacteria pstC ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria COG4590@1,COG4590@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component MAG.T2.42_02470 349741.Amuc_1304 9.2e-141 507.3 Verrucomicrobiae pstA ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2ITN9@203494,46SBK@74201,COG0581@1,COG0581@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component MAG.T2.42_02471 118005.AWNK01000011_gene144 7.8e-95 354.0 Bacteria pstB GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria COG1117@1,COG1117@2 NA|NA|NA P ATPase-coupled phosphate ion transmembrane transporter activity MAG.T2.42_02473 1142394.PSMK_30780 2.3e-126 460.7 Planctomycetes smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2IY32@203682,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T2.42_02474 1142394.PSMK_18820 4.4e-41 176.4 Planctomycetes flgI ko:K02394 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 2IY0C@203682,COG1413@1,COG1413@2,COG1706@1,COG1706@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation MAG.T2.42_02478 344747.PM8797T_06040 2.1e-113 416.0 Planctomycetes yegT ko:K05820 ko00000,ko02000 2.A.1.27 Bacteria 2J534@203682,COG0477@1,COG2814@2 NA|NA|NA EGP MFS_1 like family MAG.T2.42_02479 1142394.PSMK_14220 1.3e-145 523.5 Planctomycetes ko:K02347 ko00000,ko03400 Bacteria 2IWW1@203682,COG1387@1,COG1387@2,COG1796@1,COG1796@2 NA|NA|NA L DNA polymerase MAG.T2.42_02480 1142394.PSMK_21110 3.4e-229 801.2 Planctomycetes sdhA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05640 Bacteria 2IX3A@203682,COG1053@1,COG1053@2 NA|NA|NA C succinate dehydrogenase or fumarate reductase, flavoprotein MAG.T2.42_02481 1142394.PSMK_21100 1.3e-52 213.4 Planctomycetes sdhC ko:K00241,ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 iYO844.BSU28450 Bacteria 2J0GW@203682,COG2009@1,COG2009@2 NA|NA|NA C succinate dehydrogenase MAG.T2.42_02482 314230.DSM3645_07246 1.3e-11 76.6 Planctomycetes Bacteria 2EAFJ@1,2J12W@203682,334IY@2 NA|NA|NA S Domain of unknown function (DUF1844) MAG.T2.42_02483 1142394.PSMK_25040 6.8e-11 75.1 Bacteria Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity MAG.T2.42_02484 477641.MODMU_4409 1.6e-07 62.8 Frankiales yraN ko:K07460 ko00000 Bacteria 2IQ3X@201174,4ETCV@85013,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family MAG.T2.42_02485 1125863.JAFN01000001_gene1137 9.9e-36 157.1 Deltaproteobacteria guaA_1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1MUDH@1224,2WQGN@28221,42TJM@68525,COG0518@1,COG0518@2 NA|NA|NA F PFAM Glutamine amidotransferase class-I MAG.T2.42_02487 589865.DaAHT2_0905 3.8e-65 255.4 Desulfobacterales cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFX@1224,2MIG5@213118,2WJC3@28221,42MND@68525,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) MAG.T2.42_02489 1210884.HG799466_gene12670 2.3e-125 455.3 Planctomycetes cysK 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXCX@203682,COG0031@1,COG0031@2 NA|NA|NA E cysteine synthase MAG.T2.42_02491 1442599.JAAN01000011_gene359 7.7e-11 75.9 Xanthomonadales 3.5.2.18 ko:K15358 ko00760,ko01120,map00760,map01120 R07984 RC01933 ko00000,ko00001,ko01000 Bacteria 1R40Z@1224,1S3FZ@1236,1X54C@135614,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T2.42_02492 1142394.PSMK_31070 8.6e-42 177.2 Planctomycetes scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 2IZNB@203682,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves MAG.T2.42_02494 644966.Tmar_0094 1.1e-35 156.4 Clostridia 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 1UV64@1239,24HTS@186801,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T2.42_02495 502025.Hoch_6539 1.5e-19 104.8 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_02496 1142394.PSMK_05000 3.6e-133 481.9 Planctomycetes 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2IZ5X@203682,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T2.42_02499 1267533.KB906737_gene1718 2.8e-82 313.2 Acidobacteria Bacteria 3Y3HT@57723,COG0457@1,COG0457@2 NA|NA|NA S ASPIC and UnbV MAG.T2.42_02504 768671.ThimaDRAFT_0622 8.8e-55 221.9 Chromatiales glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1MU8H@1224,1RQWX@1236,1WZGU@135613,COG0584@1,COG0584@2 NA|NA|NA C PFAM Glycerophosphoryl diester phosphodiesterase MAG.T2.42_02506 1125973.JNLC01000001_gene91 1.9e-30 139.0 Alphaproteobacteria Bacteria 1REMY@1224,2EIJF@1,2U7V3@28211,33CAS@2 NA|NA|NA S Protein of unknown function with HXXEE motif MAG.T2.42_02507 1122134.KB893650_gene1718 5.7e-13 82.4 Gammaproteobacteria Bacteria 1R75B@1224,1RQRG@1236,28MAI@1,2ZAP6@2 NA|NA|NA MAG.T2.42_02509 1173023.KE650771_gene2163 7.1e-22 112.5 Cyanobacteria Bacteria 1GFR6@1117,2E8PN@1,3330T@2 NA|NA|NA MAG.T2.42_02513 1155718.KB891887_gene6726 6.8e-08 64.7 Actinobacteria Bacteria 2GKAG@201174,COG0494@1,COG0494@2 NA|NA|NA L nUDIX hydrolase MAG.T2.42_02514 926550.CLDAP_34280 1.9e-161 575.9 Chloroflexi pcd GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2G5JZ@200795,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T2.42_02515 688269.Theth_0442 1.1e-173 616.7 Thermotogae glgP 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 2GCCY@200918,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties MAG.T2.42_02516 342610.Patl_3301 3.4e-18 100.9 Gammaproteobacteria Bacteria 1NG8A@1224,1SF0K@1236,2E9WM@1,3342C@2 NA|NA|NA MAG.T2.42_02517 396588.Tgr7_2529 5.4e-134 485.3 Chromatiales mrpA GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05559,ko:K05565,ko:K05566 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1MW2M@1224,1RNKN@1236,1WVXV@135613,COG1009@1,COG1009@2,COG2111@1,COG2111@2 NA|NA|NA CP Na H antiporter MAG.T2.42_02518 331678.Cphamn1_0075 1.3e-30 139.4 Chlorobi mnhB ko:K05559,ko:K05565,ko:K05566 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1FF8H@1090,COG2111@1,COG2111@2 NA|NA|NA P PFAM Na H antiporter MnhB subunit-related protein MAG.T2.42_02519 290512.Paes_0096 1.2e-23 115.9 Chlorobi mrpC ko:K05567 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1FF5Y@1090,COG1006@1,COG1006@2 NA|NA|NA C PFAM NADH-ubiquinone oxidoreductase chain 4L MAG.T2.42_02520 765914.ThisiDRAFT_0603 3.2e-106 392.5 Chromatiales mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05568 ko00000,ko02000 2.A.63.1,2.A.63.2 iSB619.SA_RS04615 Bacteria 1MURB@1224,1RQBG@1236,1WVZA@135613,COG0651@1,COG0651@2 NA|NA|NA CP PFAM NADH Ubiquinone plastoquinone MAG.T2.42_02521 1128421.JAGA01000003_gene2887 1e-23 116.7 Bacteria mrpE ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria COG1863@1,COG1863@2 NA|NA|NA P multisubunit Na H antiporter MnhE subunit MAG.T2.42_02522 1142394.PSMK_06560 1.8e-10 72.0 Planctomycetes mnhF ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 2J1KY@203682,COG2212@1,COG2212@2 NA|NA|NA P Multiple resistance and pH regulation protein F (MrpF / PhaF) MAG.T2.42_02523 1142394.PSMK_06550 1.1e-16 92.8 Planctomycetes mrpG ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 2J494@203682,COG1320@1,COG1320@2 NA|NA|NA P protein synonym multiple resistance and pH homeostasis protein G MAG.T2.42_02524 1114959.SZMC14600_15510 5.2e-24 118.2 Pseudonocardiales rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 2GTKX@201174,4DY8U@85010,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit MAG.T2.42_02525 232346.JHQL01000004_gene1866 1.4e-23 117.1 Oceanospirillales rsmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 ko:K15984 ko00000,ko01000,ko03009 Bacteria 1MX8Z@1224,1RMIB@1236,1XIK1@135619,COG0742@1,COG0742@2 NA|NA|NA J Specifically methylates the guanosine in position 1516 of 16S rRNA MAG.T2.42_02526 640081.Dsui_2043 5.6e-156 557.8 Rhodocyclales cbs 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738,ko:K12339,ko:K18926 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338,M00715 R00891,R00897,R01290,R03132,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.3.30 Bacteria 1MUBE@1224,2KYDB@206389,2VPRG@28216,COG0031@1,COG0031@2,COG0517@1,COG0517@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme MAG.T2.42_02527 414684.RC1_1986 4.3e-135 488.0 Rhodospirillales metC GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K10764 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU57@1224,2JPIA@204441,2TW14@28211,COG0626@1,COG0626@2 NA|NA|NA E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases MAG.T2.42_02528 1123508.JH636442_gene4220 1.4e-171 609.8 Planctomycetes 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2IX4R@203682,COG0514@1,COG0514@2 NA|NA|NA L DEAD DEAH box helicase MAG.T2.42_02529 518766.Rmar_2225 4.2e-07 60.5 Bacteroidetes Order II. Incertae sedis Bacteria 1FKBP@1100069,4PF9I@976,COG5660@1,COG5660@2 NA|NA|NA S Putative zinc-finger MAG.T2.42_02530 314230.DSM3645_06149 3.6e-44 184.9 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2J0GI@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.42_02531 1142394.PSMK_25710 4.4e-38 165.2 Planctomycetes scpA ko:K05896 ko00000,ko03036 Bacteria 2IZIR@203682,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves MAG.T2.42_02532 1142394.PSMK_25700 1.8e-68 266.5 Planctomycetes kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K02467,ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_1278,iAPECO1_1312.APECO1_3818,iECABU_c1320.ECABU_c29780,iECED1_1282.ECED1_3157,iECH74115_1262.ECH74115_4519,iECOK1_1307.ECOK1_3081,iECS88_1305.ECS88_2971,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSF_1195.SF2731,iSFxv_1172.SFxv_3550,iS_1188.S2922,iUTI89_1310.UTI89_C3070,iYL1228.KPN_03607,iZ_1308.Z4560,ic_1306.c3262 Bacteria 2IX0R@203682,COG0517@1,COG0517@2,COG0794@1,COG0794@2 NA|NA|NA M Belongs to the SIS family. GutQ KpsF subfamily MAG.T2.42_02533 1142394.PSMK_08510 4.8e-96 359.0 Planctomycetes dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2IXQ4@203682,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication MAG.T2.42_02534 1142394.PSMK_08500 3.5e-18 97.4 Planctomycetes rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J0SS@203682,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family MAG.T2.42_02535 530564.Psta_4382 6.4e-121 441.0 Planctomycetes kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 2IX0H@203682,COG0156@1,COG0156@2 NA|NA|NA H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA MAG.T2.42_02536 1142394.PSMK_11940 5.6e-94 351.3 Planctomycetes mrp ko:K03593 ko00000,ko03029,ko03036 Bacteria 2IXIF@203682,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP MAG.T2.42_02538 443143.GM18_1584 1.1e-42 181.0 Proteobacteria wcfG Bacteria 1NC1U@1224,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 MAG.T2.42_02539 314345.SPV1_00487 7.4e-33 148.3 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T2.42_02540 1142394.PSMK_15650 4.8e-35 156.4 Bacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1277@1,COG1277@2 NA|NA|NA MAG.T2.42_02541 1142394.PSMK_15640 5.4e-93 348.2 Planctomycetes pilH ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IY18@203682,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase MAG.T2.42_02542 1142394.PSMK_15630 4.7e-27 129.4 Bacteria ko:K04088,ko:K14393 M00742 ko00000,ko00002,ko01000,ko02000 2.A.21.7 Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion MAG.T2.42_02543 1218075.BAYA01000025_gene5365 2.2e-23 116.7 Burkholderiaceae hflC2 ko:K04087 M00742 ko00000,ko00002,ko01000 Bacteria 1K5EI@119060,1P392@1224,2W9W1@28216,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues MAG.T2.42_02544 1142394.PSMK_15610 3.5e-55 223.4 Bacteria Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion MAG.T2.42_02545 1142394.PSMK_15560 6.2e-39 168.3 Planctomycetes pilI Bacteria 2IYX5@203682,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component MAG.T2.42_02547 243233.MCA1674 1.1e-71 278.1 Methylococcales wspA ko:K03406,ko:K13487 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,1S0J1@1236,1XGYS@135618,COG0840@1,COG0840@2 NA|NA|NA NT similarity to SP P39216 MAG.T2.42_02552 314230.DSM3645_19478 1.5e-123 449.9 Planctomycetes 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 2IX0S@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A MAG.T2.42_02553 446466.Cfla_0890 3.5e-07 62.8 Actinobacteria wcoG Bacteria 2GN7G@201174,COG1409@1,COG1409@2,COG3291@1,COG3291@2 NA|NA|NA P PFAM PKD domain containing protein MAG.T2.42_02554 1255043.TVNIR_3073 1.6e-56 226.9 Gammaproteobacteria Bacteria 1NT1Q@1224,1RP9M@1236,COG1752@1,COG1752@2 NA|NA|NA S esterase of the alpha-beta hydrolase superfamily MAG.T2.42_02556 1142394.PSMK_25100 3.4e-21 108.6 Planctomycetes lptE GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 ko:K03643 ko00000,ko02000 1.B.42.1 iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 Bacteria 2J0MT@203682,COG2980@1,COG2980@2 NA|NA|NA M Lipopolysaccharide-assembly MAG.T2.42_02557 1142394.PSMK_25110 3.4e-57 229.2 Bacteria bamD ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria COG4105@1,COG4105@2 NA|NA|NA S cell envelope organization MAG.T2.42_02558 1246474.ANBE01000011_gene3533 2e-25 123.2 Streptosporangiales dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GK3P@201174,4EK8V@85012,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain (presumed) MAG.T2.42_02559 1142394.PSMK_22790 1.6e-61 243.0 Planctomycetes ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2IX9S@203682,COG1191@1,COG1191@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T2.42_02560 1232410.KI421428_gene1170 3.9e-84 318.5 Desulfuromonadales pilT-1 ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1MU3J@1224,2WJ28@28221,42M7F@68525,43TYQ@69541,COG2805@1,COG2805@2 NA|NA|NA NU PFAM type II secretion system protein E MAG.T2.42_02561 388467.A19Y_3529 4.1e-12 79.7 Oscillatoriales ko:K14194 ko05150,map05150 ko00000,ko00001 Bacteria 1G0MJ@1117,1H9HP@1150,COG4932@1,COG4932@2 NA|NA|NA M PFAM Collagen-binding surface protein Cna-like, B-type domain MAG.T2.42_02567 1173028.ANKO01000135_gene2487 1.9e-109 403.7 Oscillatoriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1GQAG@1117,1H979@1150,COG2304@1,COG2304@2 NA|NA|NA T protein containing a von Willebrand factor type A (vWA) domain MAG.T2.42_02568 1142394.PSMK_01040 1.7e-83 316.6 Planctomycetes ko:K03554 ko00000,ko03400 Bacteria 2IX80@203682,COG2974@1,COG2974@2 NA|NA|NA L May be involved in recombination MAG.T2.42_02571 794903.OPIT5_06705 1.9e-147 529.6 Opitutae ybaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03455 ko00000 2.A.37 Bacteria 3K8Q4@414999,46UN8@74201,COG1226@1,COG1226@2,COG4651@1,COG4651@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T2.42_02572 204669.Acid345_1015 2.4e-76 292.0 Acidobacteriia hpnH Bacteria 2JI93@204432,3Y2JV@57723,COG0535@1,COG0535@2 NA|NA|NA S TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH MAG.T2.42_02574 292564.Cyagr_1738 1.6e-19 101.7 Cyanobium Bacteria 1G97T@1117,22T49@167375,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 MAG.T2.42_02575 1278073.MYSTI_04811 5e-27 127.9 Proteobacteria Bacteria 1NWY5@1224,COG4335@1,COG4335@2 NA|NA|NA L DNA alkylation repair enzyme MAG.T2.42_02576 28072.Nos7524_4685 1.5e-17 95.1 Nostocales Bacteria 1GA44@1117,1HPUY@1161,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T2.42_02577 32057.KB217478_gene2273 4.9e-19 100.5 Nostocales Bacteria 1G6S3@1117,1HU94@1161,COG4634@1,COG4634@2 NA|NA|NA MAG.T2.42_02579 584708.Apau_0050 4.5e-07 60.8 Synergistetes Bacteria 3TCFR@508458,COG3636@1,COG3636@2 NA|NA|NA K TIGRFAM addiction module antidote protein MAG.T2.42_02580 1192034.CAP_8277 3.3e-41 176.4 Myxococcales ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1QZBM@1224,2WQPM@28221,2Z3I2@29,42TG7@68525,COG3266@1,COG3266@2 NA|NA|NA S FG-GAP repeat MAG.T2.42_02581 1211114.ALIP01000161_gene1626 2.5e-20 104.8 Xanthomonadales Bacteria 1QGHR@1224,1TDXI@1236,1XB55@135614,COG3801@1,COG3801@2 NA|NA|NA S YjbR MAG.T2.42_02582 595460.RRSWK_02990 1.1e-84 320.1 Planctomycetes yfbL Bacteria 2J035@203682,COG2234@1,COG2234@2 NA|NA|NA S Peptidase family M28 MAG.T2.42_02583 1237149.C900_01179 5.9e-46 190.3 Cytophagia Bacteria 47RED@768503,4NQGY@976,COG4898@1,COG4898@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T2.42_02586 661478.OP10G_2239 7.6e-47 194.5 Bacteria 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T2.42_02587 1121129.KB903368_gene872 5.4e-38 165.6 Bacteroidetes ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 4P759@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T2.42_02588 504472.Slin_0264 6.9e-62 244.6 Cytophagia Bacteria 47N8N@768503,4NJN7@976,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T2.42_02589 287.DR97_5888 2.2e-18 98.2 Pseudomonas aeruginosa group ysdA ko:K03704 ko00000,ko03000 Bacteria 1N6YM@1224,1SCMX@1236,1YG6J@136841,COG1278@1,COG1278@2,COG3326@1,COG3326@2 NA|NA|NA K Protein of unknown function (DUF1294) MAG.T2.42_02591 478741.JAFS01000001_gene1833 3.2e-18 99.0 unclassified Verrucomicrobia Bacteria 37G95@326457,46YWX@74201,COG2930@1,COG2930@2 NA|NA|NA S Las17-binding protein actin regulator MAG.T2.42_02592 502025.Hoch_1100 3.7e-58 233.4 Myxococcales Bacteria 1MV1P@1224,2X5YN@28221,2YUEJ@29,42PPB@68525,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.42_02593 1192034.CAP_4066 2e-10 74.3 Bacteria 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T2.42_02594 1142394.PSMK_11750 5.5e-95 355.9 Planctomycetes ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2IY62@203682,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Belongs to the GSP D family MAG.T2.42_02596 1142394.PSMK_04770 3.8e-128 464.9 Planctomycetes carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 2IWSY@203682,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family MAG.T2.42_02597 1142394.PSMK_24470 1.5e-158 567.0 Planctomycetes priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IY1F@203682,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA MAG.T2.42_02598 1123060.JONP01000024_gene2533 1.3e-59 236.9 Rhodospirillales ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 1MVG0@1224,2JVDJ@204441,2TRQX@28211,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase MAG.T2.42_02600 1142394.PSMK_12310 1.3e-228 799.3 Planctomycetes dnaK ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2IWWS@203682,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein MAG.T2.42_02602 382464.ABSI01000010_gene3658 1.4e-53 216.9 Bacteria cysQ 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria COG1218@1,COG1218@2 NA|NA|NA P 3'(2'),5'-bisphosphate nucleotidase activity MAG.T2.42_02603 1089550.ATTH01000001_gene1131 3.7e-12 79.3 Bacteroidetes Order II. Incertae sedis ko:K18353 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01504 Bacteria 1FJIP@1100069,4PESB@976,COG3021@1,COG3021@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family MAG.T2.42_02604 1142394.PSMK_29730 2.6e-43 182.6 Planctomycetes Bacteria 2IYV8@203682,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T2.42_02605 5741.EDO77369 7.1e-23 114.0 Eukaryota Eukaryota 291T2@1,2SG2C@2759 NA|NA|NA MAG.T2.42_02608 1144313.PMI10_03221 5.1e-24 119.0 Flavobacteriia dsbE ko:K02199,ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1I3CM@117743,4NQ70@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.42_02609 706587.Desti_3299 3.1e-53 216.5 Deltaproteobacteria norM-2 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 1MUAM@1224,2WM16@28221,42MX0@68525,COG0534@1,COG0534@2 NA|NA|NA V PFAM Multi antimicrobial extrusion protein MatE MAG.T2.42_02610 1210884.HG799462_gene8065 1.2e-13 83.6 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.42_02611 935863.AWZR01000011_gene83 1e-49 205.7 Gammaproteobacteria Bacteria 1MV1P@1224,1RSKR@1236,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T2.42_02612 179408.Osc7112_4861 1.4e-22 113.6 Oscillatoriales Bacteria 1G24Z@1117,1HC54@1150,COG1708@1,COG1708@2 NA|NA|NA S nucleotidyltransferase activity MAG.T2.42_02613 1142394.PSMK_02530 3.3e-52 212.2 Planctomycetes pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.5,2.7.8.8 ko:K00995,ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800,R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 2IZHR@203682,COG1183@1,COG1183@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T2.42_02615 661478.OP10G_0856 5.6e-156 558.1 Bacteria yuxL 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T2.42_02616 4792.ETI52789 1.5e-91 343.6 Peronosporales GO:0003674,GO:0003824,GO:0006508,GO:0006518,GO:0006575,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009636,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0042219,GO:0042221,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0070011,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1990748 3.5.1.16,3.5.4.3,5.3.1.23 ko:K01438,ko:K01487,ko:K08963 ko00220,ko00230,ko00270,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00230,map00270,map01100,map01110,map01130,map01210,map01230 M00028,M00034,M00845 R00669,R01676,R04420,R09107 RC00064,RC00204,RC00300,RC01151 ko00000,ko00001,ko00002,ko01000 Eukaryota 3QB7S@4776,COG0402@1,COG0624@1,KOG2275@2759,KOG3968@2759 NA|NA|NA EFQ Peptidase dimerisation domain MAG.T2.42_02617 324602.Caur_2210 7.2e-79 301.2 Chloroflexia alx GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K05794 ko00000 Bacteria 2G66P@200795,376HN@32061,COG0861@1,COG0861@2 NA|NA|NA P PFAM Integral membrane protein TerC MAG.T2.42_02618 314230.DSM3645_15985 6.7e-46 190.3 Planctomycetes trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXA5@203682,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine MAG.T2.42_02619 1379270.AUXF01000001_gene2292 3.9e-55 223.0 Bacteria Bacteria COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process MAG.T2.42_02620 661478.OP10G_2860 9.5e-284 983.4 Bacteria tri1 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08676 ko00000,ko01000,ko01002 Bacteria COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M serine-type peptidase activity MAG.T2.42_02621 1392501.JIAC01000001_gene1151 1.7e-31 142.9 Negativicutes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,4H4DR@909932,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes MAG.T2.42_02624 1142394.PSMK_22530 3.7e-33 148.7 Planctomycetes Bacteria 29XVD@1,2J4D9@203682,30JMP@2 NA|NA|NA MAG.T2.42_02625 1142394.PSMK_31540 3.7e-35 156.4 Planctomycetes ko:K06381 ko00000 Bacteria 2J08W@203682,COG2385@1,COG2385@2 NA|NA|NA D Stage II sporulation protein MAG.T2.42_02626 1142394.PSMK_16480 3.4e-70 271.9 Planctomycetes rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXMK@203682,COG0202@1,COG0202@2,COG0457@1,COG0457@2 NA|NA|NA K rna polymerase alpha MAG.T2.42_02627 237368.SCABRO_02587 5.9e-11 76.6 Bacteria fhaB GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T2.42_02629 1254432.SCE1572_22375 5.5e-12 79.7 Myxococcales 3.4.21.50,3.4.24.25 ko:K01337,ko:K08604,ko:K20276 ko02024,ko05110,ko05111,map02024,map05110,map05111 ko00000,ko00001,ko01000,ko01002 Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2,COG3227@1,COG3227@2,COG4412@1,COG4412@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_02631 1122176.KB903565_gene3379 1.6e-21 112.1 Sphingobacteriia rapB2 ko:K07004,ko:K12548 ko00000 Bacteria 1IXV1@117747,4PKD0@976,COG2304@1,COG2304@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_02632 502025.Hoch_6539 1.8e-13 84.0 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_02635 1442599.JAAN01000035_gene641 1.3e-124 453.8 Xanthomonadales Bacteria 1RCA0@1224,1S08B@1236,1X5NR@135614,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T2.42_02636 401053.AciPR4_3741 4.5e-44 184.5 Acidobacteriia Bacteria 2JKQB@204432,3Y6Y3@57723,COG2128@1,COG2128@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T2.42_02637 118166.JH976537_gene4795 3.9e-115 421.4 Oscillatoriales Bacteria 1G0CB@1117,1HAJ3@1150,COG0596@1,COG0596@2 NA|NA|NA S alpha/beta hydrolase fold MAG.T2.42_02640 1142394.PSMK_08040 1.6e-144 520.0 Planctomycetes valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Bacteria 2IWU4@203682,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner MAG.T2.42_02641 631362.Thi970DRAFT_02731 2.5e-110 406.0 Chromatiales cls ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1MWUW@1224,1RPQG@1236,1WXED@135613,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol MAG.T2.42_02642 1142394.PSMK_02080 3.2e-35 154.8 Planctomycetes greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2IZWB@203682,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides MAG.T2.42_02644 886293.Sinac_2774 2e-116 425.6 Planctomycetes Bacteria 2IXQ0@203682,COG1262@1,COG1262@2 NA|NA|NA S PFAM Formylglycine-generating sulfatase enzyme MAG.T2.42_02645 756272.Plabr_4346 2.2e-06 60.1 Planctomycetes ftsQ ko:K03589,ko:K06438 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 2J0ZH@203682,COG1589@1,COG1589@2 NA|NA|NA M Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly MAG.T2.42_02646 1142394.PSMK_20580 3.8e-44 184.9 Planctomycetes ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2IZHT@203682,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family MAG.T2.42_02649 1121459.AQXE01000006_gene118 1.1e-101 377.1 Desulfovibrionales ko:K07133 ko00000 Bacteria 1MWBT@1224,2MGF1@213115,2WJP4@28221,42NJU@68525,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T2.42_02650 497965.Cyan7822_1073 2.8e-26 127.1 Cyanothece Bacteria 1GJ01@1117,3KK5Z@43988,COG2931@1,COG2931@2 NA|NA|NA Q PFAM C-type lectin domain protein MAG.T2.42_02651 85643.Tmz1t_4068 5.8e-51 208.8 Rhodocyclales Bacteria 1RJP5@1224,2CC4B@1,2KZ3X@206389,2VU2U@28216,3267W@2 NA|NA|NA MAG.T2.42_02653 118168.MC7420_7371 3.8e-23 115.2 Bacteria Bacteria COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_02654 575540.Isop_1218 5.5e-179 634.0 Planctomycetes Bacteria 2IXQ5@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) MAG.T2.42_02655 575540.Isop_1217 1.3e-216 760.4 Planctomycetes Bacteria 2J53S@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C MAG.T2.42_02656 555779.Dthio_PD2680 3.3e-22 111.3 Desulfovibrionales vapC Bacteria 1N44Q@1224,2MFGY@213115,2WRVS@28221,42UNG@68525,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T2.42_02657 521674.Plim_0125 6.1e-24 117.5 Planctomycetes Bacteria 2J0AU@203682,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T2.42_02658 1449063.JMLS01000021_gene868 1.1e-41 176.8 Paenibacillaceae nfsA 1.5.1.38,1.5.1.39 ko:K10678,ko:K19285,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 R05705,R05706,R08014,R08017,R08042 RC00126,RC00250 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,26TNF@186822,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C NAD(P)H-dependent oxidoreductase MAG.T2.42_02659 1122185.N792_12800 2.4e-37 161.8 Xanthomonadales Bacteria 1MYT0@1224,1S70Q@1236,1XBQV@135614,2DM8U@1,3273Z@2 NA|NA|NA S Signal peptide protein MAG.T2.42_02660 439235.Dalk_1221 4.4e-06 60.1 Bacteria Bacteria COG2304@1,COG2304@2 NA|NA|NA IU oxidoreductase activity MAG.T2.42_02663 443255.SCLAV_1744 2.5e-255 888.6 Actinobacteria leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T2.42_02665 35128.Thaps11211 1.2e-23 118.6 Bacillariophyta Eukaryota 2E9TD@1,2SG44@2759,2XGW2@2836 NA|NA|NA O Metallo-peptidase family M12B Reprolysin-like MAG.T2.42_02667 1379270.AUXF01000002_gene1230 1.8e-10 73.9 Gemmatimonadetes Bacteria 1ZU68@142182,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity MAG.T2.42_02668 1298863.AUEP01000002_gene1582 1.9e-08 65.5 Actinobacteria Bacteria 2BNAP@1,2GTB3@201174,32GYA@2 NA|NA|NA MAG.T2.42_02669 886293.Sinac_6281 1.1e-117 430.3 Planctomycetes ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2IXPG@203682,COG1196@1,COG1196@2,COG1674@1,COG1674@2 NA|NA|NA D DNA segregation ATPase FtsK SpoIIIE MAG.T2.42_02671 1248916.ANFY01000007_gene2452 1e-67 264.6 Sphingomonadales imuB 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1MU5X@1224,2JZYV@204457,2TQVR@28211,COG0389@1,COG0389@2 NA|NA|NA L Nucleotidyltransferase DNA polymerase involved in DNA repair MAG.T2.42_02672 1142394.PSMK_20680 1.2e-18 100.9 Bacteria GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K14160 ko00000,ko03400 Bacteria COG4544@1,COG4544@2 NA|NA|NA L Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division MAG.T2.42_02673 1173026.Glo7428_0636 1.9e-12 78.6 Cyanobacteria ko:K07075 ko00000 Bacteria 1G90U@1117,COG1669@1,COG1669@2 NA|NA|NA S DNA polymerase beta domain protein region MAG.T2.42_02674 498848.TaqDRAFT_3958 2.5e-21 108.2 Deinococcus-Thermus Bacteria 1WKJ0@1297,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 MAG.T2.42_02677 1396141.BATP01000039_gene1267 1.1e-19 105.1 Bacteria Bacteria COG2442@1,COG2442@2 NA|NA|NA K InterPro IPR007367 MAG.T2.42_02678 1255043.TVNIR_3853 2.8e-18 98.2 Proteobacteria Bacteria 1N9QC@1224,COG4634@1,COG4634@2 NA|NA|NA MAG.T2.42_02679 1123508.JH636439_gene1006 1.1e-118 433.7 Planctomycetes yrvN ko:K07452,ko:K07478 ko00000,ko01000,ko02048 Bacteria 2IX8G@203682,COG2256@1,COG2256@2 NA|NA|NA L ATPase related to the helicase subunit of the Holliday junction resolvase MAG.T2.42_02680 1444309.JAQG01000110_gene1774 2.7e-17 95.9 Paenibacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,26ZIC@186822,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family MAG.T2.42_02681 1142394.PSMK_18550 4.7e-39 169.1 Planctomycetes enhA_2 ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2J0C4@203682,COG1376@1,COG1376@2,COG1388@1,COG1388@2 NA|NA|NA M ErfK YbiS YcfS YnhG family protein MAG.T2.42_02682 1242864.D187_009349 1.5e-65 257.3 Proteobacteria 3.4.11.10 ko:K05994 ko00000,ko01000,ko01002 Bacteria 1R86D@1224,COG2133@1,COG2133@2,COG3291@1,COG3291@2 NA|NA|NA G COG2133 Glucose sorbosone dehydrogenases MAG.T2.42_02684 1142394.PSMK_24550 5.8e-154 551.2 Planctomycetes ptsI 2.7.1.202,2.7.3.9 ko:K02768,ko:K08483,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 Bacteria 2IX08@203682,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) MAG.T2.42_02685 1142394.PSMK_24570 5.9e-133 482.6 Planctomycetes rne GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 3.1.26.12 ko:K08300 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2IWSS@203682,COG1530@1,COG1530@2 NA|NA|NA J TIGRFAM ribonuclease, Rne Rng family MAG.T2.42_02688 1142394.PSMK_10470 2.6e-22 113.2 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity MAG.T2.42_02689 575540.Isop_3432 6.7e-46 192.2 Planctomycetes lnt ko:K03820 ko00000,ko01000 GT2 Bacteria 2IWUW@203682,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins MAG.T2.42_02690 1142394.PSMK_10710 3.2e-89 335.1 Planctomycetes accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016020,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0034645,GO:0042546,GO:0042759,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,5.4.99.2,6.4.1.2 ko:K01849,ko:K01962,ko:K01963 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00375,M00376,M00741 R00742,R00833,R04386 RC00040,RC00253,RC00367,RC00395 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS20740,iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 2IXWA@203682,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA MAG.T2.42_02691 1031711.RSPO_c02892 1.4e-14 86.7 Burkholderiaceae gpmB 3.1.3.73,5.4.2.12 ko:K02226,ko:K15634 ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00122 R01518,R04594,R11173 RC00017,RC00536 ko00000,ko00001,ko00002,ko01000 Bacteria 1K3KI@119060,1NPC4@1224,2VQTE@28216,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase MAG.T2.42_02692 575540.Isop_0616 2e-29 136.7 Planctomycetes msrB 1.8.4.11,1.8.4.12 ko:K12267 ko00000,ko01000 Bacteria 2J06Z@203682,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T2.42_02693 1244869.H261_18582 1.7e-63 249.6 Alphaproteobacteria ttg2A ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MUSD@1224,2TR2I@28211,COG1127@1,COG1127@2 NA|NA|NA Q ABC transporter MAG.T2.42_02695 1146883.BLASA_1767 7.7e-07 61.2 Frankiales Bacteria 2DRPS@1,2GXSD@201174,33CHR@2,4EX0H@85013 NA|NA|NA MAG.T2.42_02696 344747.PM8797T_16233 2.9e-84 318.9 Planctomycetes 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 2J2Y8@203682,COG1622@1,COG1622@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T2.42_02697 344747.PM8797T_16238 1e-280 972.6 Planctomycetes coxA 1.9.3.1 ko:K02274,ko:K15408 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2J2GN@203682,COG0843@1,COG0843@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T2.42_02698 344747.PM8797T_16243 4.5e-48 198.4 Bacteria ko:K02862 ko00000 Bacteria COG3336@1,COG3336@2 NA|NA|NA G cytochrome c oxidase MAG.T2.42_02700 344747.PM8797T_16253 8.8e-53 213.4 Planctomycetes 1.3.5.1,1.3.5.4 ko:K00240,ko:K03886 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00151,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2J13H@203682,COG0723@1,COG0723@2 NA|NA|NA C PFAM Rieske 2Fe-2S domain MAG.T2.42_02705 1027371.GOALK_099_00060 3.6e-198 698.7 Gordoniaceae rep 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GISS@201174,4GA89@85026,COG0210@1,COG0210@2 NA|NA|NA L UvrD-like helicase C-terminal domain MAG.T2.42_02706 1121381.JNIV01000005_gene2591 3.4e-36 159.5 Bacteria Bacteria COG0551@1,COG0551@2 NA|NA|NA L DNA topological change MAG.T2.42_02714 219305.MCAG_03829 9.9e-27 126.7 Actinobacteria Bacteria 2EK9X@1,2IGXR@201174,33E07@2 NA|NA|NA MAG.T2.42_02719 1480694.DC28_05150 1.4e-44 186.4 Bacteria pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria COG1071@1,COG1071@2 NA|NA|NA C oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor MAG.T2.42_02720 1142394.PSMK_00250 9.2e-125 453.4 Planctomycetes pdhB 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2753 Bacteria 2IYRX@203682,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain MAG.T2.42_02721 1142394.PSMK_12640 5.2e-95 355.1 Planctomycetes pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2IXEX@203682,COG0508@1,COG0508@2 NA|NA|NA C TIGRFAM pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form MAG.T2.42_02722 1142394.PSMK_28950 6.5e-45 187.6 Planctomycetes blaB4 1.1.1.306,3.1.2.6 ko:K00153,ko:K01069 ko00620,map00620 R01736,R09129,R10301 RC00004,RC00069,RC00137,RC01715 ko00000,ko00001,ko01000 Bacteria 2IZHE@203682,COG0491@1,COG0491@2 NA|NA|NA P COG0491 Zn-dependent hydrolases, including glyoxylases MAG.T2.42_02724 1144275.COCOR_05683 3.5e-43 181.8 Myxococcales btuE 1.11.1.22,1.11.1.9 ko:K00432,ko:K20207 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 iJN678.slr1992 Bacteria 1RD1R@1224,2WNWS@28221,2YV4G@29,42S35@68525,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family MAG.T2.42_02725 1122614.JHZF01000013_gene4023 2.6e-12 79.0 Alphaproteobacteria Bacteria 1PC15@1224,2UHIV@28211,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein MAG.T2.42_02728 1173021.ALWA01000030_gene883 2e-74 286.2 Cyanobacteria sbtA ko:K07086 ko00000 Bacteria 1G0ST@1117,COG3329@1,COG3329@2 NA|NA|NA S Sodium-dependent bicarbonate transporter MAG.T2.42_02729 330214.NIDE4282 1.1e-73 284.3 Nitrospirae ymxG ko:K07263 ko00000,ko01000,ko01002 Bacteria 3J0I5@40117,COG0612@1,COG0612@2 NA|NA|NA S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MAG.T2.42_02730 237368.SCABRO_00906 3e-102 379.4 Planctomycetes pqqL ko:K07263 ko00000,ko01000,ko01002 Bacteria 2IYKK@203682,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T2.42_02731 595460.RRSWK_05134 4.5e-27 129.8 Bacteria Bacteria COG2374@1,COG2374@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2 NA|NA|NA S protein secretion MAG.T2.42_02732 530564.Psta_4414 2.1e-14 85.5 Planctomycetes atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2J00X@203682,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane MAG.T2.42_02733 179408.Osc7112_1824 9e-09 66.2 Oscillatoriales vapC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07064 ko00000 Bacteria 1G6FV@1117,1HBMX@1150,COG1848@1,COG1848@2 NA|NA|NA S PIN domain MAG.T2.42_02734 251221.35211948 2.8e-48 199.9 Cyanobacteria Bacteria 1G1UY@1117,COG0457@1,COG0457@2 NA|NA|NA S Alternative locus ID MAG.T2.42_02735 756272.Plabr_1665 6.2e-264 916.4 Planctomycetes 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 2IXNZ@203682,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase MAG.T2.42_02737 306281.AJLK01000117_gene4216 1.6e-23 115.9 Bacteria Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.42_02738 1298867.AUES01000040_gene988 3.3e-185 654.4 Bradyrhizobiaceae Bacteria 1NX2A@1224,2TTBA@28211,3JX1U@41294,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1214) MAG.T2.42_02741 1267535.KB906767_gene3273 4.3e-10 72.4 Acidobacteriia wapA 1.1.2.6 ko:K05889 R03136 ko00000,ko01000 Bacteria 2JP5Q@204432,3Y99I@57723,COG1520@1,COG1520@2,COG3292@1,COG3292@2,COG4733@1,COG4733@2,COG5520@1,COG5520@2 NA|NA|NA M Chitobiase/beta-hexosaminidase C-terminal domain MAG.T2.42_02742 1101191.KI912577_gene1939 6.6e-09 70.1 Methylobacteriaceae ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1JSCD@119045,1MWJA@1224,2TRIX@28211,COG2319@1,COG2319@2,COG3474@1,COG3474@2 NA|NA|NA C Cytochrome c, class I MAG.T2.42_02743 575540.Isop_2930 6.3e-30 139.0 Planctomycetes ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 2J1GU@203682,COG3258@1,COG3258@2 NA|NA|NA C Protein of unknown function (DUF3365) MAG.T2.42_02744 1403819.BATR01000067_gene2010 2.9e-118 431.8 Verrucomicrobiae ppk2 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2IVFJ@203494,46UWN@74201,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T2.42_02745 1396418.BATQ01000120_gene3055 2.3e-179 635.6 Verrucomicrobiae ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 2IVJF@203494,46TUB@74201,COG0659@1,COG0659@2 NA|NA|NA P Sulfate permease family MAG.T2.42_02746 530564.Psta_1179 1.5e-38 166.8 Planctomycetes Bacteria 28IQM@1,2IY3I@203682,2Z8QA@2 NA|NA|NA S Anti-sigma-K factor rskA MAG.T2.42_02747 1210884.HG799463_gene9989 1.3e-38 166.8 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZXS@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T2.42_02748 357804.Ping_2325 3.2e-11 73.6 Gammaproteobacteria GO:0005575,GO:0005576,GO:0005615,GO:0044421 Bacteria 1RD06@1224,1RSMY@1236,COG2335@1,COG2335@2 NA|NA|NA M Secreted and surface protein containing fasciclin-like repeats MAG.T2.42_02749 675635.Psed_6033 1e-39 169.5 Pseudonocardiales tauX ko:K07255,ko:K21700 ko00430,map00430 R01685 RC00062 ko00000,ko00001,ko01000 Bacteria 2GR1G@201174,4EDKX@85010,COG3631@1,COG3631@2 NA|NA|NA S SnoaL-like polyketide cyclase MAG.T2.42_02750 314264.ROS217_19797 1.1e-12 79.3 Alphaproteobacteria ko:K06919 ko00000 Bacteria 1MYGF@1224,2TTNY@28211,COG1199@1,COG1199@2,COG3598@1,COG3598@2 NA|NA|NA KL Phage plasmid primase, P4 family domain protein MAG.T2.42_02751 644282.Deba_2566 2.2e-44 186.0 Deltaproteobacteria Bacteria 1RE56@1224,293DJ@1,2WUVQ@28221,2ZQW1@2,42ZFY@68525 NA|NA|NA MAG.T2.42_02752 1417296.U879_13630 2.4e-145 522.7 Alphaproteobacteria queC 3.5.2.10,6.3.4.20 ko:K01470,ko:K06920 ko00330,ko00790,ko01100,map00330,map00790,map01100 R01884,R09978 RC00615,RC00959 ko00000,ko00001,ko01000,ko03016 Bacteria 1MXFU@1224,2U0CR@28211,COG0603@1,COG0603@2 NA|NA|NA F PP-loop superfamily ATPase MAG.T2.42_02753 1121271.AUCM01000027_gene96 3e-07 60.8 Alphaproteobacteria Bacteria 1N9IM@1224,2UH9G@28211,COG3311@1,COG3311@2 NA|NA|NA K Transcriptional regulator MAG.T2.42_02754 1123072.AUDH01000023_gene751 9.5e-213 746.9 Rhodospirillales ko:K06919 ko00000 Bacteria 1MV7I@1224,2JW3C@204441,2TRS2@28211,COG3378@1,COG3378@2,COG3598@1,COG3598@2 NA|NA|NA L D5 N terminal like MAG.T2.42_02755 1142394.PSMK_24340 6.4e-62 244.2 Planctomycetes Bacteria 2IYFB@203682,COG0515@1,COG0515@2 NA|NA|NA KLT PFAM Protein kinase domain MAG.T2.42_02757 493475.GARC_5284 5.4e-67 262.3 Alteromonadaceae ko:K02660 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko02035,ko02044 Bacteria 1MV70@1224,1RPPQ@1236,465BG@72275,COG1858@1,COG1858@2 NA|NA|NA P Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.42_02758 316274.Haur_1906 3.2e-18 98.6 Chloroflexia Bacteria 2G7D8@200795,376E5@32061,COG2128@1,COG2128@2 NA|NA|NA S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T2.42_02759 1142394.PSMK_21320 1.7e-250 872.5 Planctomycetes gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2IXF8@203682,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T2.42_02760 886293.Sinac_1026 4.1e-46 192.6 Planctomycetes Bacteria 2IYVB@203682,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_02761 941449.dsx2_0703 3.6e-21 108.6 Desulfovibrionales Bacteria 1PGI1@1224,2MBF3@213115,2X09X@28221,43A97@68525,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T2.42_02762 941449.dsx2_0704 3.2e-59 236.1 Deltaproteobacteria ko:K12340,ko:K15725 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,1.B.17.2.2,2.A.6.2 Bacteria 1PYD8@1224,2WKZG@28221,42P1Y@68525,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T2.42_02763 1254432.SCE1572_17235 0.0 1241.9 Deltaproteobacteria ko:K03296 ko00000 2.A.6.2 Bacteria 1MU48@1224,2WJ8D@28221,42MF6@68525,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.42_02769 265072.Mfla_2428 4.9e-54 219.2 Nitrosomonadales yjiK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1NGZM@1224,2KN1C@206350,2W33C@28216,COG3204@1,COG3204@2 NA|NA|NA S SdiA-regulated MAG.T2.42_02770 96561.Dole_2043 1.6e-27 131.0 Desulfobacterales Bacteria 1MZHI@1224,2MN6K@213118,2WUM4@28221,43BRC@68525,COG1800@1,COG1800@2,COG2885@1,COG2885@2,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats MAG.T2.42_02771 1380394.JADL01000014_gene224 1.6e-56 226.9 Rhodospirillales oxdD 4.1.1.2 ko:K01569 ko00630,ko01100,map00630,map01100 R00522 RC00321 ko00000,ko00001,ko01000 Bacteria 1MUZA@1224,2JV4E@204441,2TTMU@28211,COG2140@1,COG2140@2 NA|NA|NA G Cupin MAG.T2.42_02773 69042.WH5701_06631 3.8e-66 258.8 Synechococcus Bacteria 1GRNG@1117,1H2G8@1129,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T2.42_02775 1142394.PSMK_03930 1.3e-145 523.1 Planctomycetes glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 iG2583_1286.G2583_3081,iIT341.HP0183 Bacteria 2IXNV@203682,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism MAG.T2.42_02776 1100720.ALKN01000024_gene1443 3.5e-35 154.8 Comamonadaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1RCY4@1224,2VR5W@28216,4ADKI@80864,COG0219@1,COG0219@2 NA|NA|NA J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide MAG.T2.42_02777 1121374.KB891586_gene2632 3.4e-23 114.4 Gammaproteobacteria hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1RFWH@1224,1S5GE@1236,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family MAG.T2.42_02778 1121129.KB903360_gene3542 1.8e-79 302.8 Porphyromonadaceae speB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 22XZG@171551,2FSS3@200643,4NE01@976,COG0010@1,COG0010@2 NA|NA|NA E Arginase family MAG.T2.42_02783 1123242.JH636435_gene2962 1.5e-171 609.4 Planctomycetes Bacteria 2IX1H@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) MAG.T2.42_02784 243090.RB10051 8.3e-12 76.6 Planctomycetes Bacteria 2IYC4@203682,COG2010@1,COG2010@2,COG3748@1,COG3748@2 NA|NA|NA C Protein of unknown function (DUF1549) MAG.T2.42_02786 903818.KI912268_gene1689 3.2e-130 471.9 Bacteria ko:K07133 ko00000 Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily MAG.T2.42_02787 1206101.AZXC01000005_gene2844 4.4e-58 232.3 Actinobacteria Bacteria 2I6N2@201174,COG4188@1,COG4188@2 NA|NA|NA S Chlorophyllase enzyme MAG.T2.42_02788 589865.DaAHT2_2628 5.8e-11 73.9 Desulfobacterales Bacteria 1RJ4K@1224,2MNKV@213118,2WT5M@28221,42WUI@68525,COG3744@1,COG3744@2 NA|NA|NA S PIN domain MAG.T2.42_02790 1123377.AUIV01000024_gene120 6.2e-53 213.4 Xanthomonadales Bacteria 1N08M@1224,1SZRB@1236,1X7PV@135614,COG0346@1,COG0346@2 NA|NA|NA E COG0346 Lactoylglutathione lyase and related lyases MAG.T2.42_02791 1142394.PSMK_11680 5.5e-23 113.2 Planctomycetes mqnE GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXUS@203682,COG1060@1,COG1060@2 NA|NA|NA H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate MAG.T2.42_02792 216432.CA2559_03750 6.2e-09 67.4 Flavobacteriia ko:K07107 ko00000,ko01000 Bacteria 1I42Y@117743,4NSIG@976,COG0824@1,COG0824@2 NA|NA|NA S thioesterase MAG.T2.42_02793 1142394.PSMK_26230 5.5e-74 285.4 Planctomycetes dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2IYAC@203682,COG2027@1,COG2027@2 NA|NA|NA M D-Ala-D-Ala carboxypeptidase 3 (S13) family MAG.T2.42_02794 1038859.AXAU01000016_gene6885 7.4e-45 187.6 Bradyrhizobiaceae ko:K09992 ko00000 Bacteria 1R5XA@1224,2U51F@28211,3K5VQ@41294,COG3828@1,COG3828@2 NA|NA|NA S Trehalose utilisation MAG.T2.42_02795 575540.Isop_1161 2.5e-162 579.3 Planctomycetes ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 ko:K01972,ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378,R00382 RC00005,RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IXIC@203682,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T2.42_02797 1142394.PSMK_15780 8.7e-30 138.7 Bacteria lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 Bacteria COG0795@1,COG0795@2 NA|NA|NA M lipopolysaccharide-transporting ATPase activity MAG.T2.42_02798 525897.Dbac_2308 4.7e-119 434.5 Deltaproteobacteria Bacteria 1MWAU@1224,2WJM6@28221,42PWW@68525,COG3177@1,COG3177@2 NA|NA|NA S PFAM filamentation induced by cAMP protein Fic MAG.T2.42_02799 1122963.AUHB01000008_gene3417 7.4e-246 856.7 Methylocystaceae arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,2.1.2.9,5.1.3.2 ko:K00604,ko:K01784,ko:K10011,ko:K12449,ko:K21332 ko00052,ko00520,ko00523,ko00670,ko00970,ko01100,ko01130,ko01503,map00052,map00520,map00523,map00670,map00970,map01100,map01130,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R01384,R01386,R02984,R03940,R07658,R07660,R11472 RC00026,RC00165,RC00289,RC00508,RC01575,RC01811,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 iPC815.YPO2420,iSFV_1184.SFV_2325 Bacteria 1MU4Q@1224,2TSWX@28211,36X6M@31993,COG0223@1,COG0223@2,COG0451@1,COG0451@2 NA|NA|NA J Formyl transferase, C-terminal domain MAG.T2.42_02800 104623.Ser39006_00436 3.5e-109 401.7 Serratia arnC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0044464,GO:0071944,GO:0099621 2.4.2.53 ko:K10012 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8 GT2 iAPECO1_1312.APECO1_4307,iE2348C_1286.E2348C_2398,iECABU_c1320.ECABU_c25880,iECED1_1282.ECED1_2720,iECOK1_1307.ECOK1_2490,iECP_1309.ECP_2297,iECS88_1305.ECS88_2403,iLF82_1304.LF82_0138,iNRG857_1313.NRG857_11430,iUMN146_1321.UM146_05530,iUTI89_1310.UTI89_C2536,ic_1306.c2796 Bacteria 1MWE5@1224,1RPCE@1236,405RC@613,COG0463@1,COG0463@2 NA|NA|NA I Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides MAG.T2.42_02801 1225785.CM001983_gene2 4.3e-53 214.5 Dickeya arnB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 ko:K07806 ko00520,ko01503,ko02020,map00520,map01503,map02020 M00721,M00761 R07659 RC00006,RC01514 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 iSFxv_1172.SFxv_2574 Bacteria 1MUPN@1224,1RMCS@1236,2JDHV@204037,COG0399@1,COG0399@2 NA|NA|NA M Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides MAG.T2.42_02802 314230.DSM3645_22174 1.2e-44 186.4 Planctomycetes ko:K07007 ko00000 Bacteria 2IWW4@203682,COG2081@1,COG2081@2 NA|NA|NA S HI0933-like protein MAG.T2.42_02803 644966.Tmar_0077 1.2e-92 347.4 Clostridiales incertae sedis gltX 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 1TPJC@1239,2482P@186801,3WCIN@538999,COG0008@1,COG0008@2,COG1384@1,COG1384@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) MAG.T2.42_02804 1142394.PSMK_11180 2.7e-32 145.2 Planctomycetes ko:K07095 ko00000 Bacteria 2IZQH@203682,COG0622@1,COG0622@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain MAG.T2.42_02805 1123401.JHYQ01000043_gene762 2.8e-11 74.3 Bacteria Bacteria COG2161@1,COG2161@2 NA|NA|NA D toxin-antitoxin pair type II binding MAG.T2.42_02806 93220.LV28_00470 9.4e-123 448.0 Burkholderiaceae hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.3.1.12,2.7.11.1,3.6.4.13 ko:K00627,ko:K03310,ko:K03578,ko:K12132 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko01001 2.A.25 Bacteria 1K087@119060,1MUEQ@1224,2VI3R@28216,COG0508@1,COG0508@2,COG1643@1,COG1643@2 NA|NA|NA L Atp-dependent helicase MAG.T2.42_02807 429009.Adeg_1581 2.4e-10 70.9 Thermoanaerobacterales mqnD ko:K07083,ko:K11785 ko00130,ko01110,map00130,map01110 R08589 RC02330 ko00000,ko00001,ko01000 Bacteria 1U8UK@1239,24BT2@186801,42I6Z@68295,COG2107@1,COG2107@2 NA|NA|NA H Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T2.42_02810 595460.RRSWK_05083 2.5e-79 302.8 Planctomycetes Bacteria 2IYXX@203682,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.42_02812 1165096.ARWF01000001_gene33 3.5e-38 165.2 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.42_02813 1144275.COCOR_03792 2.8e-123 449.1 Myxococcales rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MU49@1224,2WIY6@28221,2YU80@29,42MGZ@68525,COG0513@1,COG0513@2 NA|NA|NA JKL Belongs to the DEAD box helicase family MAG.T2.42_02815 1192034.CAP_8276 1.1e-51 211.1 Myxococcales 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R0E4@1224,2X84M@28221,2YUU3@29,43EEC@68525,COG1520@1,COG1520@2,COG3055@1,COG3055@2 NA|NA|NA S FG-GAP repeat MAG.T2.42_02816 314230.DSM3645_21889 5.7e-95 354.8 Planctomycetes 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IXJ7@203682,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T2.42_02817 765869.BDW_09280 4.2e-44 184.9 Proteobacteria Bacteria 1NYWX@1224,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily C-terminal MAG.T2.42_02819 1123242.JH636436_gene646 6.5e-25 120.6 Planctomycetes Bacteria 2J081@203682,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T2.42_02820 1142394.PSMK_12470 1.7e-32 145.6 Planctomycetes rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZVX@203682,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site MAG.T2.42_02821 935863.AWZR01000003_gene2869 1.2e-65 256.5 Xanthomonadales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1MUN1@1224,1RMWC@1236,1X3NC@135614,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family MAG.T2.42_02822 1142394.PSMK_07000 4.5e-21 107.1 Planctomycetes rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2J0X7@203682,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family MAG.T2.42_02823 195250.CM001776_gene536 1.1e-31 143.7 Cyanobacteria Bacteria 1G69P@1117,COG1994@1,COG1994@2 NA|NA|NA S PFAM Peptidase family M50 MAG.T2.42_02824 1122137.AQXF01000002_gene150 8.5e-35 153.3 Alphaproteobacteria moaC GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 1RCYZ@1224,2U747@28211,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) MAG.T2.42_02825 861299.J421_4478 2.2e-70 273.5 Gemmatimonadetes Bacteria 1ZU9S@142182,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T2.42_02826 864051.BurJ1DRAFT_3550 1e-18 100.1 Proteobacteria Bacteria 1R1U7@1224,2CD7S@1,32RX7@2 NA|NA|NA MAG.T2.42_02827 926550.CLDAP_21260 2.9e-74 285.0 Chloroflexi sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 2G5Q9@200795,COG0605@1,COG0605@2 NA|NA|NA C Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T2.42_02828 4530.OS02T0787250-01 1.5e-07 64.7 Poales Viridiplantae 28ZDB@1,2R67K@2759,386Z7@33090,3GUWJ@35493,3INV8@38820,3M2HB@4447 NA|NA|NA MAG.T2.42_02830 1177154.Y5S_01761 5.7e-55 221.5 Oceanospirillales yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 ko:K06192 ko00000 Bacteria 1MU1T@1224,1RN89@1236,1XJ1N@135619,COG3008@1,COG3008@2 NA|NA|NA Q Paraquat-inducible protein B MAG.T2.42_02831 395493.BegalDRAFT_2132 1.7e-19 102.8 Thiotrichales pqiA1 ko:K03808 ko00000 Bacteria 1MWG1@1224,1RM9Z@1236,462EX@72273,COG2995@1,COG2995@2 NA|NA|NA S paraquat-inducible protein A MAG.T2.42_02832 483219.LILAB_25525 2.6e-73 282.7 Myxococcales pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1MWAB@1224,2WJQR@28221,2YU78@29,42NMR@68525,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family MAG.T2.42_02833 1173028.ANKO01000155_gene4474 1e-32 146.4 Oscillatoriales Bacteria 1G79E@1117,1HBMU@1150,COG2402@1,COG2402@2 NA|NA|NA S PIN domain MAG.T2.42_02838 1504981.KO116_3681 8.6e-42 177.6 Oceanospirillales Bacteria 1N3QR@1224,1RQTW@1236,1XR9G@135619,COG3666@1,COG3666@2 NA|NA|NA L Transposase domain (DUF772) MAG.T2.42_02839 351348.Maqu_0982 2e-13 82.0 Alteromonadaceae Bacteria 1QW5T@1224,1T44C@1236,46D6Z@72275,COG3666@1,COG3666@2 NA|NA|NA L Transposase DDE domain MAG.T2.42_02841 1173028.ANKO01000044_gene805 2.7e-13 80.9 Oscillatoriales ko:K07075 ko00000 Bacteria 1G804@1117,1HCHE@1150,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T2.42_02843 864069.MicloDRAFT_00059580 6.2e-67 261.2 Alphaproteobacteria 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1Q2N4@1224,2TZ6C@28211,COG0322@1,COG0322@2 NA|NA|NA L Domain of unknown function (DUF4357) MAG.T2.42_02845 85929.N1QLS7 5.3e-09 68.2 Dothideomycetidae Fungi 1ZYBA@147541,38HN2@33154,3MK8D@451867,3NX9N@4751,3QRB0@4890,COG0666@1,KOG4177@2759 NA|NA|NA M CorA-like Mg2+ transporter protein MAG.T2.42_02846 1142394.PSMK_07060 8.6e-11 74.7 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.42_02847 237368.SCABRO_00978 3.2e-18 99.4 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T2.42_02848 313624.NSP_32490 4.2e-38 165.2 Nostocales 2.4.1.21 ko:K00703,ko:K01990,ko:K02519,ko:K11904 ko00500,ko01100,ko01110,ko02026,ko03070,map00500,map01100,map01110,map02026,map03070 M00254,M00334,M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000,ko02044,ko03012,ko03029 3.A.1,3.A.23.1 GT5 Bacteria 1GFF5@1117,1HT8J@1161,COG3675@1,COG3675@2,COG5373@1,COG5373@2 NA|NA|NA I Lamin Tail Domain MAG.T2.42_02849 863239.AFIZ01000046_gene2180 8e-17 94.0 Corynebacteriaceae argR GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0032991,GO:0032993,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140110,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 22KU4@1653,2GKA5@201174,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes MAG.T2.42_02850 1453496.AT03_01485 1.3e-84 320.1 Gammaproteobacteria argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1MVJ6@1224,1RNMX@1236,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde MAG.T2.42_02852 309801.trd_A0115 1.1e-17 98.6 Thermomicrobia cmr2 ko:K07016,ko:K19076 ko00000,ko02048 Bacteria 27YXJ@189775,2G6PV@200795,COG1353@1,COG1353@2 NA|NA|NA S CRISPR-associated protein MAG.T2.42_02855 886293.Sinac_6103 4e-64 251.5 Planctomycetes kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 Bacteria 2IYWF@203682,COG1212@1,COG1212@2 NA|NA|NA H Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria MAG.T2.42_02856 521674.Plim_0675 6.8e-10 72.4 Planctomycetes Bacteria 2J01V@203682,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T2.42_02857 1142394.PSMK_24190 5e-35 154.5 Planctomycetes def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2IZ6R@203682,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions MAG.T2.42_02858 1142394.PSMK_29220 4.3e-55 221.9 Planctomycetes fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria 2IYU1@203682,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus MAG.T2.42_02860 595460.RRSWK_05132 5.9e-31 141.7 Bacteria ko:K07004,ko:K15125,ko:K20276 ko02024,ko05133,map02024,map05133 ko00000,ko00001,ko00536 Bacteria COG2374@1,COG2374@2,COG3210@1,COG3210@2,COG3391@1,COG3391@2,COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process MAG.T2.42_02862 497321.C664_16260 8.5e-98 364.4 Rhodocyclales Bacteria 1P0KH@1224,2KV1R@206389,2VKZE@28216,COG0486@1,COG0486@2 NA|NA|NA S GTP-binding HSR1-like protein MAG.T2.42_02863 497321.C664_16255 5.9e-45 189.5 Rhodocyclales Bacteria 1QSC2@1224,28JMK@1,2KVU9@206389,2VKUE@28216,2Z9E3@2 NA|NA|NA S Protein of unknown function (DUF2868) MAG.T2.42_02864 344747.PM8797T_32060 1.2e-11 75.9 Planctomycetes tatA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2J14F@203682,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system MAG.T2.42_02865 56780.SYN_02504 1e-67 264.2 Deltaproteobacteria mltA GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K08304 ko00000,ko01000,ko01011 GH102 iECABU_c1320.ECABU_c30840 Bacteria 1MXD4@1224,2WKKF@28221,42P7C@68525,COG2821@1,COG2821@2 NA|NA|NA M PFAM MltA domain protein MAG.T2.42_02866 886293.Sinac_1932 9.1e-78 298.5 Planctomycetes Bacteria 2J55E@203682,COG2706@1,COG2706@2 NA|NA|NA G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.42_02867 1123242.JH636435_gene1022 4.6e-67 261.9 Planctomycetes hhoA 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IYNW@203682,COG0265@1,COG0265@2 NA|NA|NA O C-terminal PDZ domain MAG.T2.42_02870 1382356.JQMP01000001_gene1018 1e-45 192.2 Thermomicrobia Bacteria 27YVB@189775,2GBD6@200795,COG3420@1,COG3420@2 NA|NA|NA P Periplasmic copper-binding protein (NosD) MAG.T2.42_02871 414684.RC1_1690 1.8e-29 135.6 Rhodospirillales Bacteria 1RDBN@1224,2JYKU@204441,2VFA9@28211,COG3335@1,COG3335@2 NA|NA|NA L Transposase and inactivated MAG.T2.42_02872 452637.Oter_1117 1.5e-07 64.3 Bacteria ko:K07666 ko02020,ko02024,map02020,map02024 M00453 ko00000,ko00001,ko00002,ko02022 Bacteria COG4625@1,COG4625@2 NA|NA|NA T pathogenesis MAG.T2.42_02875 382464.ABSI01000021_gene382 6e-146 524.2 Verrucomicrobiae Bacteria 2ITHB@203494,46UZ5@74201,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase MAG.T2.42_02876 1142394.PSMK_26480 5.1e-41 175.3 Planctomycetes holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IZVJ@203682,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III, delta' subunit MAG.T2.42_02878 234267.Acid_3620 1.1e-26 126.3 Acidobacteria Bacteria 3Y4XK@57723,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T2.42_02879 42256.RradSPS_2282 5.1e-16 90.5 Bacteria Bacteria COG4636@1,COG4636@2 NA|NA|NA D protein conserved in cyanobacteria MAG.T2.42_02880 208439.AJAP_36870 4.1e-110 405.2 Pseudonocardiales algD 1.1.1.132,1.1.1.22 ko:K00012,ko:K00066 ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020 M00014,M00129,M00361,M00362 R00286,R00880 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQB@201174,4E15T@85010,COG1004@1,COG1004@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T2.42_02881 443143.GM18_1584 5.4e-21 109.0 Proteobacteria wcfG Bacteria 1NC1U@1224,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 MAG.T2.42_02882 886293.Sinac_6796 3.7e-70 273.1 Planctomycetes Bacteria 2IX8E@203682,COG0265@1,COG0265@2,COG2234@1,COG2234@2 NA|NA|NA O PA domain MAG.T2.42_02884 1121920.AUAU01000005_gene982 3.5e-104 385.2 Acidobacteria ycaQ ko:K09927 ko00000 Bacteria 3Y96S@57723,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain MAG.T2.42_02885 314230.DSM3645_17685 8.7e-112 410.2 Planctomycetes mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1360 Bacteria 2IY7S@203682,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate MAG.T2.42_02886 1142394.PSMK_23270 2.7e-79 302.8 Planctomycetes trkA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2IXXC@203682,COG0569@1,COG0569@2 NA|NA|NA C TRK potassium uptake system protein (TrkA-2) MAG.T2.42_02887 1142394.PSMK_13210 1.5e-89 337.0 Planctomycetes trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 ko:K03498,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651 Bacteria 2IYFA@203682,COG0168@1,COG0168@2 NA|NA|NA P COG0168 Trk-type K transport systems, membrane components MAG.T2.42_02890 1121033.AUCF01000001_gene2401 1.1e-49 203.4 Rhodospirillales 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 Bacteria 1QWJU@1224,2JZ1W@204441,2TWZZ@28211,COG4106@1,COG4106@2 NA|NA|NA S Methyltransferase domain MAG.T2.42_02891 452637.Oter_2172 3.8e-120 438.3 Opitutae chrA ko:K07240 ko00000,ko02000 2.A.51.1 Bacteria 3K8DA@414999,46X82@74201,COG2059@1,COG2059@2 NA|NA|NA P TIGRFAM chromate transporter, chromate ion transporter (CHR) family MAG.T2.42_02892 717772.THIAE_08195 1.2e-95 356.7 Gammaproteobacteria Bacteria 1QPXG@1224,1S1R1@1236,COG4249@1,COG4249@2 NA|NA|NA S Caspase domain MAG.T2.42_02894 1142394.PSMK_21250 8.1e-109 400.6 Planctomycetes gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 iSFV_1184.SFV_2953 Bacteria 2IWRE@203682,COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T2.42_02895 1125863.JAFN01000001_gene3410 4.8e-34 152.1 Deltaproteobacteria lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MUX6@1224,2WJJY@28221,42M4X@68525,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.42_02896 1142394.PSMK_07170 4.2e-142 512.3 Planctomycetes yaeT ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 2IWWA@203682,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein assembly complex, YaeT protein MAG.T2.42_02897 1142394.PSMK_18860 3.3e-77 295.4 Planctomycetes thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iJN678.thiE,iNJ661.Rv0414c Bacteria 2IY16@203682,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) MAG.T2.42_02898 1142394.PSMK_11890 1e-64 253.8 Planctomycetes phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 2IXEB@203682,COG1235@1,COG1235@2 NA|NA|NA S of the beta-lactamase superfamily I MAG.T2.42_02901 886293.Sinac_0492 8e-45 186.8 Planctomycetes rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZ7I@203682,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA MAG.T2.42_02902 1142394.PSMK_26560 3e-52 211.1 Planctomycetes rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IZR1@203682,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit MAG.T2.42_02903 886293.Sinac_3183 3.4e-44 184.9 Planctomycetes rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2IZBP@203682,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T2.42_02904 1210884.HG799471_gene14582 1.8e-61 243.0 Planctomycetes atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2IXDI@203682,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex MAG.T2.42_02906 1437824.BN940_02881 1.2e-16 94.7 Alcaligenaceae Bacteria 1MWGP@1224,2VJZR@28216,3T6ZN@506,COG1783@1,COG1783@2 NA|NA|NA S to Bacillus subtilis pbsx phage terminase large subunit xtmB SWALL XTMB_BACSU (SWALL P39786) (433 aa) fasta scores E() 0.2, 21.58 id in 417 aa, and to Yersinia pestis MAG.T2.42_02907 1430331.EP10_08955 1.6e-18 99.4 Geobacillus Bacteria 1VY3D@1239,1WHEN@129337,2DRIA@1,33BX1@2,4HX43@91061 NA|NA|NA MAG.T2.42_02914 314230.DSM3645_26904 1.6e-66 260.0 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IYZ1@203682,COG2304@1,COG2304@2 NA|NA|NA A von Willebrand factor, type A MAG.T2.42_02915 595460.RRSWK_05520 1.7e-79 303.1 Planctomycetes batA ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IYWC@203682,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A MAG.T2.42_02916 1278073.MYSTI_06256 1.4e-14 87.4 Myxococcales Bacteria 1NKJH@1224,2DQMB@1,2WSJT@28221,2YVNT@29,337KD@2,42X0X@68525 NA|NA|NA MAG.T2.42_02917 243090.RB8767 1.9e-84 319.3 Planctomycetes GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2IXT7@203682,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T2.42_02918 595460.RRSWK_05517 5e-68 264.2 Planctomycetes moxR ko:K03924 ko00000,ko01000 Bacteria 2IX23@203682,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T2.42_02919 1142394.PSMK_25340 6.5e-174 617.1 Planctomycetes ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2IWU2@203682,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins MAG.T2.42_02920 1502852.FG94_04661 1.9e-52 213.4 Oxalobacteraceae cls ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1MWUW@1224,2VI41@28216,47327@75682,COG1502@1,COG1502@2 NA|NA|NA M Phospholipase D. Active site motifs. MAG.T2.42_02921 396595.TK90_1056 2.6e-11 74.7 Gammaproteobacteria ko:K09131 ko00000 Bacteria 1QKJ0@1224,1SDPY@1236,COG1872@1,COG1872@2 NA|NA|NA S DUF167 MAG.T2.42_02922 1142394.PSMK_29910 1.1e-161 576.6 Planctomycetes uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2IWVR@203682,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision MAG.T2.42_02925 1121861.KB899911_gene1188 7.2e-43 181.4 Rhodospirillales ko:K00754 ko00000,ko01000 GT4 Bacteria 1RB4T@1224,2JUWG@204441,2UD9U@28211,COG0438@1,COG0438@2,COG4122@1,COG4122@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T2.42_02926 1121861.KB899911_gene1190 9.7e-88 330.9 Rhodospirillales 3.6.3.38 ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.103 Bacteria 1MWWC@1224,2JQDY@204441,2TU3M@28211,COG1134@1,COG1134@2 NA|NA|NA GM ATPases associated with a variety of cellular activities MAG.T2.42_02927 1121861.KB899911_gene1188 2e-53 217.6 Rhodospirillales ko:K00754 ko00000,ko01000 GT4 Bacteria 1RB4T@1224,2JUWG@204441,2UD9U@28211,COG0438@1,COG0438@2,COG4122@1,COG4122@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T2.42_02928 1123060.JONP01000010_gene2187 1.4e-21 109.4 Rhodospirillales ko:K00754 ko00000,ko01000 GT4 Bacteria 1N0DG@1224,2JUG7@204441,2V85C@28211,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T2.42_02929 1142394.PSMK_11090 0.0 1461.0 Planctomycetes carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2IXR6@203682,COG0458@1,COG0458@2 NA|NA|NA F Carbamoylphosphate synthase large subunit MAG.T2.42_02930 1183438.GKIL_3357 1.1e-96 360.5 Cyanobacteria entS ko:K08225 ko00000,ko02000 2.A.1.38 Bacteria 1G1NG@1117,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily MFS_1 MAG.T2.42_02932 1379698.RBG1_1C00001G1377 1e-25 125.2 unclassified Bacteria Bacteria 2NRD7@2323,COG4409@1,COG4409@2 NA|NA|NA G exo-alpha-(2->6)-sialidase activity MAG.T2.42_02934 1142394.PSMK_15730 3.6e-104 386.0 Planctomycetes Bacteria 2IXIT@203682,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane MAG.T2.42_02935 903818.KI912268_gene2712 3.4e-108 398.7 Bacteria ko:K07133 ko00000 Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily MAG.T2.42_02936 765912.Thimo_1120 3.5e-37 164.1 Chromatiales ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1PGVW@1224,1RX2X@1236,1X1RA@135613,COG1100@1,COG1100@2,COG4886@1,COG4886@2 NA|NA|NA G Leucine Rich repeats (2 copies) MAG.T2.42_02937 118173.KB235914_gene335 1e-25 124.0 Bacteria Bacteria COG1262@1,COG1262@2,COG4249@1,COG4249@2 NA|NA|NA S B-1 B cell differentiation MAG.T2.42_02938 1142394.PSMK_05790 2.2e-163 582.0 Planctomycetes ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2IXN9@203682,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate MAG.T2.42_02939 1142394.PSMK_26100 7.2e-20 104.8 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.42_02940 234267.Acid_6143 4.4e-36 160.2 Bacteria apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria COG1477@1,COG1477@2 NA|NA|NA H protein flavinylation MAG.T2.42_02943 1532558.JL39_02045 8e-41 174.9 Rhizobiaceae bme6 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1MWEM@1224,2U1NW@28211,4BCPY@82115,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain MAG.T2.42_02944 56107.Cylst_2426 1.1e-13 84.0 Cyanobacteria ko:K16260 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1GQ8T@1117,COG2304@1,COG2304@2 NA|NA|NA S PFAM Lectin C-type domain MAG.T2.42_02946 56107.Cylst_2426 6.8e-16 91.3 Cyanobacteria ko:K16260 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1GQ8T@1117,COG2304@1,COG2304@2 NA|NA|NA S PFAM Lectin C-type domain MAG.T2.42_02947 1458427.BAWN01000017_gene1127 4.9e-51 207.2 Proteobacteria Bacteria 1N9J5@1224,COG1487@1,COG1487@2 NA|NA|NA S PIN domain MAG.T2.42_02948 1458427.BAWN01000017_gene1128 2.1e-20 104.4 Betaproteobacteria Bacteria 1Q0B5@1224,2W539@28216,COG5450@1,COG5450@2 NA|NA|NA K Bacterial antitoxin of type II TA system, VapB MAG.T2.42_02951 1502851.FG93_01719 7.6e-30 139.4 Bradyrhizobiaceae glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 Bacteria 1MU6Y@1224,2TSG6@28211,3JUJH@41294,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain MAG.T2.42_02953 760192.Halhy_1128 5.1e-08 65.5 Sphingobacteriia Bacteria 1INSI@117747,4NFUE@976,COG3209@1,COG3209@2 NA|NA|NA M COG3209 Rhs family protein MAG.T2.42_02955 1142394.PSMK_15660 2.5e-58 233.8 Planctomycetes 2.7.7.7 ko:K02343,ko:K03749 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IXFB@203682,COG3147@1,COG3147@2 NA|NA|NA S Non-essential cell division protein that could be required for efficient cell constriction MAG.T2.42_02956 1185876.BN8_03085 9.8e-60 237.7 Cytophagia Bacteria 47UIX@768503,4NJ0F@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T2.42_02957 1173023.KE650771_gene2163 1.3e-36 160.2 Cyanobacteria Bacteria 1GFR6@1117,2E8PN@1,3330T@2 NA|NA|NA MAG.T2.42_02958 1125863.JAFN01000001_gene2832 2.8e-61 241.9 Deltaproteobacteria 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPF@1224,2WNQ5@28221,42NS5@68525,COG0179@1,COG0179@2 NA|NA|NA Q PFAM fumarylacetoacetate (FAA) hydrolase MAG.T2.42_02959 314230.DSM3645_04685 3.5e-50 204.5 Planctomycetes aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN678.aspS,iSFV_1184.SFV_1868 Bacteria 2IX6U@203682,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) MAG.T2.42_02960 768671.ThimaDRAFT_0223 5.8e-55 221.5 Gammaproteobacteria flgK ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZXB@1224,1RN1W@1236,COG4786@1,COG4786@2 NA|NA|NA N Protein of unknown function (DUF2950) MAG.T2.42_02961 639283.Snov_4209 1.5e-35 157.5 Xanthobacteraceae dacC 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1QVM5@1224,2TWI6@28211,3F18E@335928,COG3115@1,COG3115@2 NA|NA|NA D Protein of unknown function (DUF3300) MAG.T2.42_02962 1089550.ATTH01000001_gene1987 7.2e-52 212.2 Bacteroidetes Bacteria 4NKIR@976,COG2866@1,COG2866@2,COG2931@1,COG2931@2,COG3291@1,COG3291@2 NA|NA|NA Q SMART Integrin alpha beta-propellor repeat protein MAG.T2.42_02963 502025.Hoch_6539 6.9e-08 66.2 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_02965 1168065.DOK_15134 1.5e-07 64.3 unclassified Gammaproteobacteria sca4 Bacteria 1J519@118884,1PS4F@1224,1RZWB@1236,COG5183@1,COG5183@2 NA|NA|NA A domain, Protein MAG.T2.42_02966 344747.PM8797T_15326 1.8e-52 213.0 Planctomycetes Bacteria 2IZ2K@203682,2ZBM3@2,arCOG08211@1 NA|NA|NA MAG.T2.42_02968 1234364.AMSF01000015_gene3245 5.4e-15 88.6 Xanthomonadales 5.2.1.8 ko:K03773 ko00000,ko01000,ko03110 Bacteria 1RDA1@1224,1RPMP@1236,1X5YQ@135614,COG0545@1,COG0545@2 NA|NA|NA M Peptidyl-prolyl cis-trans MAG.T2.42_02970 330214.NIDE0577 2.2e-268 931.8 Bacteria Bacteria COG0433@1,COG0433@2 NA|NA|NA S helicase activity MAG.T2.42_02971 326427.Cagg_1635 1.3e-23 116.7 Chloroflexia yjeE 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 2G6YV@200795,375TA@32061,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE MAG.T2.42_02972 1142394.PSMK_26870 1.6e-49 203.4 Planctomycetes thiL GO:0008150,GO:0040007 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2977c,iYO844.BSU05900 Bacteria 2IZG9@203682,COG0611@1,COG0611@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 MAG.T2.42_02973 1142394.PSMK_14960 4.6e-95 355.1 Planctomycetes kdtA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 iECNA114_1301.ECNA114_3778,iIT341.HP0957,iUMNK88_1353.UMNK88_4417 Bacteria 2IYCJ@203682,COG1519@1,COG1519@2 NA|NA|NA M transferase MAG.T2.42_02975 1142394.PSMK_20480 2.9e-116 426.0 Planctomycetes mutL GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 2IXI2@203682,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex MAG.T2.42_02976 1123242.JH636435_gene2431 3.9e-39 168.3 Bacteria Bacteria COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.42_02977 1173028.ANKO01000195_gene5941 3.8e-29 136.0 Oscillatoriales Bacteria 1GQP5@1117,1HHYB@1150,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively MAG.T2.42_02978 118166.JH976537_gene1210 3.6e-16 94.4 Oscillatoriales 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1G1QI@1117,1H6XA@1150,COG0457@1,COG0457@2,COG2815@1,COG2815@2 NA|NA|NA O Tetratricopeptide repeat MAG.T2.42_02979 172088.AUGA01000004_gene3801 5.2e-47 193.7 Bradyrhizobiaceae ko:K06996 ko00000 Bacteria 1NDRR@1224,2UTK9@28211,3K4GV@41294,COG3324@1,COG3324@2 NA|NA|NA E translation initiation factor activity MAG.T2.42_02980 172088.AUGA01000004_gene3800 1.2e-211 742.3 Bradyrhizobiaceae 2.3.1.247 ko:K18013 ko00310,map00310 R10564 RC02728,RC03199 ko00000,ko00001,ko01000 Bacteria 1MXGN@1224,2U4WZ@28211,3K30S@41294,COG3246@1,COG3246@2 NA|NA|NA S beta-keto acid cleavage enzyme MAG.T2.42_02981 1496688.ER33_14860 3.6e-28 131.7 Bacteria Bacteria 2E06S@1,32VUR@2 NA|NA|NA MAG.T2.42_02982 398525.KB900701_gene5677 7.9e-71 273.9 Alphaproteobacteria 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1N0Z6@1224,2VGPU@28211,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T2.42_02983 1403819.BATR01000009_gene302 1.1e-206 726.1 Verrucomicrobiae 3.1.6.12 ko:K01135 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVET@203494,46TNU@74201,COG3119@1,COG3119@2 NA|NA|NA P Type I phosphodiesterase / nucleotide pyrophosphatase MAG.T2.42_02984 1397527.Q670_05870 2.7e-185 654.8 Oceanospirillales ko:K19172 ko00000,ko02048 Bacteria 1MWTW@1224,1TJAF@1236,1XP37@135619,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T2.42_02985 85643.Tmz1t_2841 5.6e-23 113.2 Rhodocyclales ko:K21495 ko00000,ko02048 Bacteria 1N09T@1224,2KZ82@206389,2VVBK@28216,COG4691@1,COG4691@2 NA|NA|NA S Arc-like DNA binding domain MAG.T2.42_02989 525903.Taci_1503 1.4e-36 159.5 Bacteria Bacteria COG3547@1,COG3547@2 NA|NA|NA L Transposase (IS116 IS110 IS902 family) MAG.T2.42_02990 671143.DAMO_2020 1.9e-22 111.7 Bacteria ko:K07483,ko:K07497 ko00000 Bacteria COG2963@1,COG2963@2 NA|NA|NA L transposase activity MAG.T2.42_02991 671143.DAMO_2019 1.5e-69 269.6 Bacteria Bacteria COG2801@1,COG2801@2 NA|NA|NA L transposition MAG.T2.42_02996 1142394.PSMK_08400 6e-107 394.4 Planctomycetes ko:K19689 ko00000,ko01000,ko01002 Bacteria 2IWWD@203682,COG2309@1,COG2309@2 NA|NA|NA E Thermophilic metalloprotease (M29) MAG.T2.42_02998 1192034.CAP_3742 7.1e-190 670.2 Myxococcales icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Bacteria 1MW3J@1224,2WJ8W@28221,2YYDJ@29,42M56@68525,COG0538@1,COG0538@2 NA|NA|NA C Isocitrate/isopropylmalate dehydrogenase MAG.T2.42_03000 756272.Plabr_3052 1.1e-185 656.4 Planctomycetes ccoO GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404,ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144,iIT341.HP0145 Bacteria 2IY0E@203682,COG2993@1,COG2993@2,COG3278@1,COG3278@2 NA|NA|NA C COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 MAG.T2.42_03002 243090.RB6353 7.5e-41 174.1 Planctomycetes ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 2J0TE@203682,COG2010@1,COG2010@2 NA|NA|NA C N-terminal domain of cytochrome oxidase-cbb3, FixP MAG.T2.42_03003 756272.Plabr_3049 5.2e-133 481.5 Planctomycetes ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IXC7@203682,COG0348@1,COG0348@2 NA|NA|NA C IG-like fold at C-terminal of FixG, putative oxidoreductase MAG.T2.42_03004 379066.GAU_3780 1.2e-30 140.6 Gemmatimonadetes braZ ko:K09792 ko00000 Bacteria 1ZUDX@142182,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome C biogenesis protein transmembrane region MAG.T2.42_03005 344747.PM8797T_06717 6.6e-117 427.6 Planctomycetes pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSbBS512_1146.SbBS512_E3351 Bacteria 2IYIS@203682,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family MAG.T2.42_03006 1142394.PSMK_18690 1.4e-72 280.0 Planctomycetes miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2IYY6@203682,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) MAG.T2.42_03009 1142394.PSMK_30700 6.3e-58 231.9 Planctomycetes ko:K18990 M00720 ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 Bacteria 2J4ZU@203682,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T2.42_03010 1142394.PSMK_30710 5.3e-286 990.7 Planctomycetes Bacteria 2IYJA@203682,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T2.42_03012 344747.PM8797T_23696 7.2e-105 387.5 Planctomycetes Bacteria 28II6@1,2IXG8@203682,2Z8JB@2 NA|NA|NA MAG.T2.42_03013 1123242.JH636435_gene2227 9.3e-89 333.6 Planctomycetes Bacteria 28MEN@1,2IZ1H@203682,2ZASA@2 NA|NA|NA MAG.T2.42_03014 344747.PM8797T_23686 4.3e-62 244.6 Planctomycetes Bacteria 29ZH8@1,2J0G3@203682,30MGZ@2 NA|NA|NA MAG.T2.42_03015 756272.Plabr_3383 1.2e-91 343.2 Planctomycetes Bacteria 28MYQ@1,2IZUC@203682,2ZB5K@2 NA|NA|NA MAG.T2.42_03016 344747.PM8797T_23676 4e-70 271.9 Planctomycetes Bacteria 2ANS9@1,2IZX5@203682,31DS7@2 NA|NA|NA MAG.T2.42_03017 888055.HMPREF9015_02229 4.9e-07 61.2 Fusobacteria ko:K03668,ko:K09914 ko00000 Bacteria 37B3Z@32066,COG3187@1,COG3187@2 NA|NA|NA O META domain protein MAG.T2.42_03018 1142394.PSMK_10130 7.1e-94 351.7 Planctomycetes clcA ko:K03281 ko00000 2.A.49 Bacteria 2IY1G@203682,COG0038@1,COG0038@2,COG0517@1,COG0517@2 NA|NA|NA P COG0038 Chloride channel protein EriC MAG.T2.42_03019 1142394.PSMK_11150 1.7e-12 78.6 Planctomycetes rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2J0KS@203682,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits MAG.T2.42_03020 1538295.JY96_19930 7.1e-40 170.6 unclassified Burkholderiales coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1KJ4Q@119065,1MVQP@1224,2VI4X@28216,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine MAG.T2.42_03022 1142394.PSMK_22080 4.7e-85 322.0 Planctomycetes dsbD 1.8.1.8 ko:K04084,ko:K08344 ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.5 Bacteria 2IXJF@203682,COG4232@1,COG4232@2 NA|NA|NA CO Cytochrome c biogenesis protein transmembrane region MAG.T2.42_03024 991905.SL003B_0807 3.4e-88 332.4 unclassified Alphaproteobacteria sdcS ko:K14445 ko00000,ko02000 2.A.47.1 Bacteria 1MUSA@1224,2TU0C@28211,4BR97@82117,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region MAG.T2.42_03025 448385.sce5045 1.2e-49 203.8 Myxococcales Bacteria 1RKSW@1224,2X3K1@28221,2YWDB@29,438AQ@68525,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase MAG.T2.42_03026 1120950.KB892793_gene2350 4.5e-12 79.0 Propionibacteriales 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2I0CJ@201174,4DS0V@85009,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain MAG.T2.42_03027 330214.NIDE0660 3.6e-102 378.6 Nitrospirae ko:K07133 ko00000 Bacteria 3J14P@40117,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T2.42_03030 426114.THI_0108 8.5e-71 273.9 unclassified Burkholderiales htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1KJAQ@119065,1MUV4@1224,2VIVB@28216,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family MAG.T2.42_03037 1142394.PSMK_20470 8.5e-96 357.1 Planctomycetes moxR ko:K03924 ko00000,ko01000 Bacteria 2IYBI@203682,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T2.42_03039 1142394.PSMK_19820 1.5e-212 745.7 Planctomycetes groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2IWZS@203682,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T2.42_03040 653733.Selin_0743 3.2e-25 120.9 Bacteria groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 ko:K04078 ko00000,ko03029,ko03110 Bacteria COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T2.42_03046 575540.Isop_3356 4.3e-105 389.8 Planctomycetes Bacteria 2IY7X@203682,COG0457@1,COG0457@2 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T2.42_03047 1121861.KB899911_gene1186 3.9e-140 505.4 Rhodospirillales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4E@1224,2JQXF@204441,2TSCY@28211,COG0367@1,COG0367@2 NA|NA|NA E COG0367 Asparagine synthase (glutamine-hydrolyzing) MAG.T2.42_03048 762903.Pedsa_0831 2.5e-14 85.5 Sphingobacteriia pel 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 Bacteria 1ITHX@117747,4NQRC@976,COG3866@1,COG3866@2 NA|NA|NA G Amb_all MAG.T2.42_03049 925409.KI911562_gene150 4.4e-39 168.7 Bacteroidetes Bacteria 4NNQC@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T2.42_03050 1121861.KB899911_gene1188 8e-58 231.5 Rhodospirillales ko:K00754 ko00000,ko01000 GT4 Bacteria 1RB4T@1224,2JUWG@204441,2UD9U@28211,COG0438@1,COG0438@2,COG4122@1,COG4122@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T2.42_03051 754035.Mesau_00703 7.4e-17 96.3 Phyllobacteriaceae Bacteria 1N482@1224,2D4E5@1,2UE4H@28211,32TGX@2,43I07@69277 NA|NA|NA MAG.T2.42_03052 536227.CcarbDRAFT_0601 6.7e-46 191.8 Clostridiaceae Bacteria 1UYV5@1239,24B0A@186801,36DRS@31979,COG0793@1,COG0793@2 NA|NA|NA M Peptidase, S41 MAG.T2.42_03053 1142394.PSMK_22400 5.9e-47 194.1 Planctomycetes frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2IYYY@203682,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another MAG.T2.42_03054 1142394.PSMK_21540 1.7e-61 243.8 Planctomycetes sprI 3.4.21.107 ko:K04771,ko:K08372 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IY5I@203682,COG0265@1,COG0265@2 NA|NA|NA O PDZ domain (Also known as DHR MAG.T2.42_03055 1142394.PSMK_07540 3.2e-66 258.8 Planctomycetes panB 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXV0@203682,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate MAG.T2.42_03057 595460.RRSWK_03474 8.5e-104 384.8 Bacteria Bacteria COG4030@1,COG4030@2 NA|NA|NA M Protein of unknown function (DUF2961) MAG.T2.42_03058 740709.A10D4_04670 4.1e-30 138.7 Idiomarinaceae Bacteria 1MUBQ@1224,1RQJT@1236,2QFPB@267893,COG1028@1,COG1028@2 NA|NA|NA IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis MAG.T2.42_03059 382464.ABSI01000010_gene3727 9.6e-79 300.8 Bacteria phaC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 ko:K03821 ko00650,map00650 R04254 RC00004 ko00000,ko00001,ko01000 iJN678.phbC Bacteria COG3243@1,COG3243@2 NA|NA|NA I poly(R)-hydroxyalkanoic acid synthase MAG.T2.42_03062 382464.ABSI01000010_gene3723 4.2e-10 72.8 Bacteria phaR Bacteria COG5394@1,COG5394@2 NA|NA|NA T Polyhydroxyalkanoate synthesis repressor PhaR MAG.T2.42_03063 1142394.PSMK_22080 1.1e-14 87.0 Planctomycetes dsbD 1.8.1.8 ko:K04084,ko:K08344 ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.5 Bacteria 2IXJF@203682,COG4232@1,COG4232@2 NA|NA|NA CO Cytochrome c biogenesis protein transmembrane region MAG.T2.42_03065 1142394.PSMK_13860 9.3e-144 516.9 Planctomycetes nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 2IWY3@203682,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination MAG.T2.42_03067 1379270.AUXF01000004_gene2937 6.5e-22 111.7 Gemmatimonadetes Bacteria 1ZV2W@142182,2E902@1,3339H@2 NA|NA|NA MAG.T2.42_03068 1121889.AUDM01000027_gene15 3.4e-07 62.4 Bacteria Bacteria COG3291@1,COG3291@2,COG4932@1,COG4932@2 NA|NA|NA M domain protein MAG.T2.42_03069 1081640.AGFU01000011_gene1303 1e-181 643.3 Alphaproteobacteria Bacteria 1MY2Y@1224,2TUIT@28211,COG1032@1,COG1032@2 NA|NA|NA C SMART Elongator protein 3 MiaB NifB MAG.T2.42_03070 983917.RGE_37670 8.2e-123 446.8 unclassified Burkholderiales rocF GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 ko:K01476,ko:K01480 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00133,M00134 R00551,R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 1KIWQ@119065,1MVFH@1224,2VJU2@28216,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T2.42_03071 382464.ABSI01000012_gene2217 1.4e-46 195.3 Bacteria Bacteria COG2374@1,COG2374@2 NA|NA|NA MAG.T2.42_03072 448385.sce9032 1e-23 117.5 Myxococcales Bacteria 1MZIX@1224,2X7PI@28221,2YVQH@29,43CDM@68525,COG0500@1,COG2226@2 NA|NA|NA Q Mycolic acid cyclopropane synthetase MAG.T2.42_03073 296587.XP_002503729.1 7.9e-15 88.2 Chlorophyta Viridiplantae 2CYB0@1,2S3AJ@2759,34I74@3041,37VHI@33090 NA|NA|NA S Aspartyl protease MAG.T2.42_03074 1142394.PSMK_22010 2e-66 259.6 Planctomycetes 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 2IXUE@203682,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T2.42_03075 765911.Thivi_0229 2.9e-72 279.3 Chromatiales 2.1.1.242,2.1.1.303,2.1.1.319 ko:K11434,ko:K15984,ko:K20421 ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922 M00830 R10963,R11216,R11217,R11219 RC00003,RC00392,RC02120,RC03388,RC03390 ko00000,ko00001,ko00002,ko01000,ko03009,ko03036 Bacteria 1R79F@1224,1RY3Z@1236,1WX5D@135613,COG2242@1,COG2242@2 NA|NA|NA H protein methyltransferase activity MAG.T2.42_03076 62928.azo2566 2.1e-37 163.3 Betaproteobacteria Bacteria 1MXWM@1224,2WEG3@28216,COG4916@1,COG4916@2 NA|NA|NA S TIR domain MAG.T2.42_03077 1142394.PSMK_05610 1.4e-95 356.7 Planctomycetes manB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321 Bacteria 2IXRS@203682,COG1109@1,COG1109@2 NA|NA|NA G PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain MAG.T2.42_03078 1189612.A33Q_3040 1.2e-52 214.2 Cytophagia 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 47P16@768503,4NF9J@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T2.42_03079 1142394.PSMK_14160 3.5e-101 374.8 Planctomycetes thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 Bacteria 2IY2Y@203682,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S MAG.T2.42_03080 270374.MELB17_02625 4.4e-11 73.6 Alteromonadaceae thiS GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149,ko:K03154 ko00730,ko01100,ko04122,map00730,map01100,map04122 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 1NG8E@1224,1SGCU@1236,46CFZ@72275,COG2104@1,COG2104@2 NA|NA|NA H ThiS family MAG.T2.42_03082 1142394.PSMK_27960 1.8e-87 330.5 Bacteria Bacteria COG1277@1,COG1277@2 NA|NA|NA MAG.T2.42_03083 1142394.PSMK_10520 2.6e-124 452.6 Planctomycetes rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2IX35@203682,COG1196@1,COG1196@2,COG1418@1,COG1418@2 NA|NA|NA D Endoribonuclease that initiates mRNA decay MAG.T2.42_03084 118161.KB235922_gene3936 7e-13 81.6 Bacteria Bacteria 2C4HM@1,2ZFRV@2 NA|NA|NA MAG.T2.42_03085 1267534.KB906754_gene2559 2.1e-10 73.6 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T2.42_03086 521674.Plim_0986 5.7e-21 108.6 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 MAG.T2.42_03089 338966.Ppro_2803 3.9e-23 114.0 Desulfuromonadales groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1MZ2X@1224,2WPZP@28221,42U7E@68525,43V9Q@69541,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T2.42_03096 761193.Runsl_3132 3.2e-52 213.4 Cytophagia ko:K14054 ko00000 Bacteria 47MR4@768503,4NHBS@976,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase MAG.T2.42_03098 215803.DB30_8779 1.7e-45 189.5 Myxococcales MA20_22045 ko:K06953 ko00000 Bacteria 1RC5G@1224,2X36F@28221,2YZDK@29,43F2X@68525,COG1407@1,COG1407@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T2.42_03099 545695.TREAZ_3035 4.9e-40 172.9 Spirochaetes rluD 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 Bacteria 2J5Z9@203691,COG0564@1,COG0564@2 NA|NA|NA J Pseudouridine synthase MAG.T2.42_03100 1192034.CAP_8033 4.1e-64 252.3 Myxococcales Bacteria 1N7SK@1224,2X37C@28221,2YUQZ@29,42PMM@68525,COG1297@1,COG1297@2 NA|NA|NA S OPT oligopeptide transporter protein MAG.T2.42_03101 252305.OB2597_05210 5.7e-10 68.9 Oceanicola Bacteria 1MZ9V@1224,2PFB9@252301,2UC0B@28211,COG3019@1,COG3019@2 NA|NA|NA S Protein of unknown function, DUF MAG.T2.42_03103 666684.AfiDRAFT_0765 8.7e-38 162.9 Bradyrhizobiaceae ychN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 ko:K06039 ko00000 Bacteria 1RDFR@1224,2U9F0@28211,3K4C9@41294,COG1553@1,COG1553@2 NA|NA|NA P DsrE/DsrF-like family MAG.T2.42_03104 1337093.MBE-LCI_1852 4.9e-185 654.1 Alphaproteobacteria Bacteria 1R2KY@1224,2TR2U@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T2.42_03105 187303.BN69_0140 3.7e-102 377.9 Alphaproteobacteria 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MUDN@1224,2U247@28211,COG0491@1,COG0491@2 NA|NA|NA P COG0491 Zn-dependent hydrolases, including glyoxylases MAG.T2.42_03106 1231185.BAMP01000161_gene4616 4e-79 301.2 Alphaproteobacteria M1-798 ko:K03892 ko00000,ko03000 Bacteria 1R71B@1224,2TVMK@28211,COG0607@1,COG0607@2,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional MAG.T2.42_03116 243090.RB6221 1.1e-189 670.6 Planctomycetes Bacteria 2IXDX@203682,COG5549@1,COG5549@2 NA|NA|NA O Domain of unknown function (DUF5117) MAG.T2.42_03117 292564.Cyagr_1403 1.2e-22 112.1 Cyanobium Bacteria 1GKGU@1117,22TRK@167375,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T2.42_03118 316067.Geob_3261 9.4e-38 164.1 Deltaproteobacteria yfhR ko:K06889 ko00000 Bacteria 1RFAF@1224,2X601@28221,43AJV@68525,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T2.42_03121 243090.RB12551 1.6e-78 299.7 Planctomycetes 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2IY69@203682,COG1398@1,COG1398@2 NA|NA|NA I COG1398 Fatty-acid desaturase MAG.T2.42_03122 379066.GAU_2094 2.7e-62 245.7 Gemmatimonadetes fieF Bacteria 1ZTCD@142182,COG0053@1,COG0053@2 NA|NA|NA U Dimerisation domain of Zinc Transporter MAG.T2.42_03123 1123508.JH636442_gene4086 2.7e-91 342.0 Planctomycetes desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2IZ45@203682,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase MAG.T2.42_03124 1122179.KB890452_gene4648 6e-07 62.4 Bacteroidetes Bacteria 4NI94@976,COG3291@1,COG3291@2,COG5563@1,COG5563@2 NA|NA|NA DZ COG3210 Large exoproteins involved in heme utilization or adhesion MAG.T2.42_03127 1192034.CAP_8276 5e-38 166.4 Myxococcales 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R0E4@1224,2X84M@28221,2YUU3@29,43EEC@68525,COG1520@1,COG1520@2,COG3055@1,COG3055@2 NA|NA|NA S FG-GAP repeat MAG.T2.42_03129 1121918.ARWE01000001_gene2378 5.1e-80 304.3 Deltaproteobacteria pcaJ 2.8.3.6 ko:K01032 ko00362,ko01100,ko01120,map00362,map01100,map01120 R02990 RC00014 ko00000,ko00001,ko01000 Bacteria 1RA4V@1224,2WJ9V@28221,42PZY@68525,COG2057@1,COG2057@2 NA|NA|NA I Acyl CoA acetate 3-ketoacid CoA transferase beta subunit MAG.T2.42_03130 1121918.ARWE01000001_gene2379 5.3e-90 337.4 Deltaproteobacteria pcaI 2.8.3.6 ko:K01031 ko00362,ko01100,ko01120,map00362,map01100,map01120 R02990 RC00014 ko00000,ko00001,ko01000 Bacteria 1MVEI@1224,2WMDH@28221,42QMC@68525,COG1788@1,COG1788@2 NA|NA|NA I 3-oxoacid CoA-transferase MAG.T2.42_03131 314254.OA2633_12730 6.6e-95 354.8 Hyphomonadaceae 5.4.3.2 ko:K01843 ko00310,map00310 R00461 RC00303 ko00000,ko00001,ko01000 Bacteria 1MUPJ@1224,2U1WH@28211,440RX@69657,COG1509@1,COG1509@2 NA|NA|NA E 4Fe-4S single cluster domain MAG.T2.42_03132 756272.Plabr_0265 5.6e-77 295.0 Planctomycetes ko:K08218,ko:K08223 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25,2.A.1.35 Bacteria 2IY9C@203682,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator Superfamily MAG.T2.42_03133 1469613.JT55_16070 4.4e-08 66.6 Bacteria ko:K14340 ko00000,ko01000,ko01003 Bacteria COG5305@1,COG5305@2 NA|NA|NA MAG.T2.42_03134 1142394.PSMK_25540 1.3e-58 233.0 Planctomycetes trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2IZJM@203682,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA MAG.T2.42_03135 153721.MYP_3421 5.5e-82 312.0 Cytophagia 3.1.3.1,3.1.3.8 ko:K01077,ko:K01083,ko:K01113,ko:K07093 ko00562,ko00730,ko00790,ko01100,ko02020,map00562,map00730,map00790,map01100,map02020 M00126 R02135,R03371,R04620 RC00017,RC00078 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 47QCY@768503,4NJ6G@976,COG4222@1,COG4222@2 NA|NA|NA S Esterase-like activity of phytase MAG.T2.42_03136 502025.Hoch_4790 1.9e-23 117.1 Myxococcales 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2WIWE@28221,2YYCB@29,42NB6@68525,COG0265@1,COG0265@2 NA|NA|NA M Domain present in PSD-95, Dlg, and ZO-1/2. MAG.T2.42_03138 1123508.JH636439_gene1751 3.1e-51 209.5 Planctomycetes ko:K07267 ko00000,ko02000 1.B.19.1 Bacteria 2IXZU@203682,COG3659@1,COG3659@2 NA|NA|NA M Belongs to the OprB family MAG.T2.42_03139 1419583.V466_02345 4.7e-53 214.5 Proteobacteria Bacteria 1R469@1224,COG1814@1,COG1814@2 NA|NA|NA S membrane MAG.T2.42_03140 460265.Mnod_2274 3.8e-203 714.5 Methylobacteriaceae ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 1JR06@119045,1MWDF@1224,2TT0G@28211,COG0659@1,COG0659@2 NA|NA|NA P PFAM Sulfate transporter antisigma-factor antagonist STAS MAG.T2.42_03141 867903.ThesuDRAFT_00874 1.2e-10 73.6 Bacteria luxR ko:K10913 ko02020,ko02024,ko05111,map02020,map02024,map05111 ko00000,ko00001,ko03000 Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator MAG.T2.42_03144 869210.Marky_1004 5e-90 337.8 Deinococcus-Thermus icmA 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 1WIX7@1297,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase MAG.T2.42_03145 1142394.PSMK_15250 2.2e-88 332.4 Planctomycetes sdhB GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX7J@203682,COG0479@1,COG0479@2 NA|NA|NA C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein MAG.T2.42_03149 243231.GSU1644 7.4e-160 570.1 Desulfuromonadales yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 ko00000,ko01000 Bacteria 1MU37@1224,2WJC1@28221,42MMK@68525,43RZT@69541,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T2.42_03150 1379270.AUXF01000001_gene2448 7.3e-53 215.3 Bacteria Bacteria COG2706@1,COG2706@2 NA|NA|NA G 6-phosphogluconolactonase activity MAG.T2.42_03151 794903.OPIT5_17495 1.3e-48 199.9 Opitutae Bacteria 28NM7@1,2ZBMT@2,3K8X8@414999,46VIC@74201 NA|NA|NA S Protein of unknown function (DUF2959) MAG.T2.42_03153 521674.Plim_1742 2.9e-27 127.9 Planctomycetes thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c45100,iYO844.BSU08790 Bacteria 2IWV7@203682,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction MAG.T2.42_03154 1142394.PSMK_28670 2.4e-54 219.5 Bacteria mdsC 2.7.1.162,2.7.1.39 ko:K02204,ko:K13059 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771,R08962 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria COG2334@1,COG2334@2 NA|NA|NA S homoserine kinase activity MAG.T2.42_03156 765913.ThidrDRAFT_0474 1.3e-50 207.2 Chromatiales MA20_23265 ko:K03446 M00701 ko00000,ko00002,ko02000 2.A.1.3 Bacteria 1RGPN@1224,1T1M7@1236,1X2VK@135613,COG0477@1,COG0477@2 NA|NA|NA U Sugar (and other) transporter MAG.T2.42_03157 1123052.AUDF01000005_gene1162 5.6e-73 280.4 Microbacteriaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM0V@201174,4FKC5@85023,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors MAG.T2.42_03158 1254432.SCE1572_30435 6.3e-88 330.9 Myxococcales deoC 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 Bacteria 1N8AG@1224,2WNEY@28221,2YYRJ@29,42S16@68525,COG0274@1,COG0274@2 NA|NA|NA H Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate MAG.T2.42_03165 243090.RB12202 1.8e-61 243.4 Planctomycetes Bacteria 2J2X9@203682,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family MAG.T2.42_03168 1463934.JOCF01000058_gene1817 4.7e-93 347.8 Actinobacteria Bacteria 2GJU1@201174,COG1028@1,COG1028@2 NA|NA|NA IQ Short-chain dehydrogenase reductase sdr MAG.T2.42_03170 330214.NIDE0660 3.8e-17 94.0 Nitrospirae ko:K07133 ko00000 Bacteria 3J14P@40117,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T2.42_03172 765420.OSCT_1185 3.2e-164 586.3 Chloroflexia tri ko:K08676 ko00000,ko01000,ko01002 Bacteria 2G64C@200795,376K3@32061,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog MAG.T2.42_03174 1123242.JH636436_gene81 8.7e-36 157.9 Planctomycetes lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IY8X@203682,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T2.42_03178 1408428.JNJP01000003_gene3518 3.2e-18 99.4 Desulfovibrionales Bacteria 1R40R@1224,2M9SG@213115,2WNW2@28221,42P0H@68525,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein MAG.T2.42_03184 1142394.PSMK_10550 4.4e-100 372.1 Planctomycetes ragB 2.7.13.3 ko:K02484,ko:K03406,ko:K07638,ko:K07639,ko:K07640,ko:K07641,ko:K07642,ko:K07644,ko:K07650,ko:K07653,ko:K07654,ko:K07711,ko:K10819,ko:K14980,ko:K18072,ko:K18143,ko:K18345,ko:K18351,ko:K19609,ko:K20487 ko01501,ko01502,ko01503,ko02020,ko02024,ko02026,ko02030,map01501,map01502,map01503,map02020,map02024,map02026,map02030 M00445,M00446,M00447,M00448,M00449,M00450,M00452,M00460,M00461,M00502,M00520,M00645,M00646,M00648,M00649,M00651,M00654,M00655,M00656,M00658,M00721,M00727,M00728,M00742,M00743,M00745,M00770,M00816 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022,ko02035 Bacteria 2IXA1@203682,COG0642@1,COG2205@2,COG2770@1,COG2770@2 NA|NA|NA T PhoQ Sensor MAG.T2.42_03186 1142394.PSMK_06230 8.3e-22 110.5 Bacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein MAG.T2.42_03190 575540.Isop_2445 5.4e-168 597.4 Planctomycetes 2.1.1.72 ko:K07319 ko00000,ko01000,ko02048 Bacteria 2IY0Z@203682,COG0863@1,COG0863@2,COG1475@1,COG1475@2 NA|NA|NA KL ParB-like nuclease domain MAG.T2.42_03191 370438.PTH_0349 1.8e-07 63.2 Peptococcaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,248DS@186801,2601K@186807,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.42_03193 1403819.BATR01000081_gene2344 1.1e-21 109.8 Bacteria rusA GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.1.22.4 ko:K01160 ko00000,ko01000,ko03400 Bacteria COG4570@1,COG4570@2 NA|NA|NA L crossover junction endodeoxyribonuclease activity MAG.T2.42_03195 1184607.AUCHE_08_00520 3e-07 60.8 Dermatophilaceae moaD 2.8.1.12 ko:K03636,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 2HSVC@201174,4F7BG@85018,COG1977@1,COG1977@2 NA|NA|NA H ThiS family MAG.T2.42_03196 478801.Ksed_19270 2e-81 309.7 Actinobacteria ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 2H1V9@201174,COG0659@1,COG0659@2 NA|NA|NA P Molybdate transporter of MFS superfamily MAG.T2.42_03197 326424.FRAAL5456 2.9e-75 289.3 Frankiales ko:K14059 ko00000 Bacteria 2GMMI@201174,4ESQP@85013,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T2.42_03202 861299.J421_2570 4.6e-75 288.5 Gemmatimonadetes queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 ko:K00773,ko:K07568 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1ZSV2@142182,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T2.42_03203 330214.NIDE2242 1.7e-88 332.8 Bacteria Bacteria COG0535@1,COG0535@2 NA|NA|NA I radical SAM domain protein MAG.T2.42_03208 1142394.PSMK_27630 1.3e-205 723.0 Planctomycetes dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYHC@203682,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) MAG.T2.42_03209 1142394.PSMK_27640 2.2e-57 229.6 Planctomycetes ispA GO:0003674,GO:0003824,GO:0004161,GO:0004311,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 iPC815.YPO3176,iSFV_1184.SFV_0386 Bacteria 2IX56@203682,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T2.42_03210 485915.Dret_2330 7.1e-21 107.5 Deltaproteobacteria Bacteria 1MZ60@1224,2WW9K@28221,431TK@68525,COG3952@1,COG3952@2 NA|NA|NA S PFAM lipid A biosynthesis domain protein MAG.T2.42_03211 1142394.PSMK_18210 1.2e-47 196.8 Planctomycetes arnC 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2IXAV@203682,COG0463@1,COG0463@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T2.42_03212 1210884.HG799462_gene8097 2.9e-21 108.2 Planctomycetes fdx GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 ko:K04755 ko00000 Bacteria 2J33M@203682,COG0633@1,COG0633@2 NA|NA|NA C 2Fe-2S iron-sulfur cluster binding domain MAG.T2.42_03213 546274.EIKCOROL_00297 2.3e-15 87.8 Neisseriales iscX GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 Bacteria 1N7C1@1224,2KRVE@206351,2VVQU@28216,COG2975@1,COG2975@2 NA|NA|NA S Iron-sulphur cluster assembly MAG.T2.42_03214 926569.ANT_16550 2e-105 389.4 Chloroflexi ltd 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 2G8B1@200795,COG0451@1,COG0451@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T2.42_03218 102232.GLO73106DRAFT_00026910 6.5e-22 112.5 Cyanobacteria ko:K11016 ko03070,map03070 ko00000,ko00001,ko02042,ko02044 Bacteria 1GC1J@1117,COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG3291@1,COG3291@2 NA|NA|NA QU Polymorphic membrane protein, Chlamydia MAG.T2.42_03219 1121920.AUAU01000001_gene2168 3.1e-44 185.7 Acidobacteria Bacteria 3Y5T2@57723,COG2519@1,COG2519@2 NA|NA|NA J Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MAG.T2.42_03220 903818.KI912268_gene3327 2.9e-64 252.7 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T2.42_03223 1205680.CAKO01000002_gene2449 1.1e-133 483.0 Rhodospirillales ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1MUCW@1224,2JPRY@204441,2TQW1@28211,COG2010@1,COG2010@2 NA|NA|NA C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex MAG.T2.42_03224 420662.Mpe_A1633 1.7e-27 128.3 unclassified Burkholderiales copB ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1KJX5@119065,1MWB0@1224,2VIIW@28216,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T2.42_03225 1499967.BAYZ01000173_gene5798 6.9e-61 241.1 unclassified Bacteria ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2NPUE@2323,COG1172@1,COG1172@2 NA|NA|NA U Branched-chain amino acid transport system / permease component MAG.T2.42_03226 502025.Hoch_6539 9.3e-18 99.4 Myxococcales Bacteria 1QT4U@1224,2X4KF@28221,2YZ72@29,437RQ@68525,COG3055@1,COG3055@2 NA|NA|NA E M6 family metalloprotease domain protein MAG.T2.42_03227 1188256.BASI01000005_gene2114 6.1e-98 363.6 Rhodovulum ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1MW12@1224,2TS4S@28211,3FCK7@34008,COG1692@1,COG1692@2 NA|NA|NA S YmdB-like protein MAG.T2.42_03228 371731.Rsw2DRAFT_2606 2.6e-83 315.5 Alphaproteobacteria Bacteria 1PDMU@1224,2U0T9@28211,COG0697@1,COG0697@2 NA|NA|NA EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily MAG.T2.42_03231 1440774.Y900_024240 1.1e-29 137.5 Mycobacteriaceae tsnR 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 234FP@1762,2GJI6@201174,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T2.42_03235 485914.Hmuk_3141 1.7e-85 323.9 Halobacteria pop Archaea 23RYH@183963,2XU9I@28890,COG1506@1,arCOG01646@2157 NA|NA|NA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases MAG.T2.42_03236 1303518.CCALI_02364 1.7e-73 283.1 Bacteria sua5 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria COG0009@1,COG0009@2 NA|NA|NA J L-threonylcarbamoyladenylate synthase MAG.T2.42_03238 1121904.ARBP01000007_gene3005 1.8e-10 74.7 Cytophagia shlA 3.1.4.46,4.2.1.118 ko:K01126,ko:K09483,ko:K11016,ko:K15125 ko00400,ko00564,ko01110,ko01130,ko03070,ko05133,map00400,map00564,map01110,map01130,map03070,map05133 R01030,R01470,R01627 RC00017,RC00425,RC00568 ko00000,ko00001,ko00536,ko01000,ko02042,ko02044 Bacteria 47SD5@768503,4PHVF@976,COG2911@1,COG2911@2,COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG3391@1,COG3391@2,COG3420@1,COG3420@2,COG4733@1,COG4733@2,COG4886@1,COG4886@2 NA|NA|NA U Leucine rich repeat MAG.T2.42_03241 880073.Calab_1105 1.3e-10 74.7 Bacteria ko:K17713,ko:K20952 ko05111,map05111 ko00000,ko00001,ko02000 1.B.33.1 Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process MAG.T2.42_03242 314266.SKA58_11960 1.3e-25 123.6 Proteobacteria Bacteria 1QTR4@1224,2E4RD@1,331HW@2 NA|NA|NA MAG.T2.42_03243 196164.23493346 1.5e-28 134.8 Bacteria Bacteria 2E4RD@1,33NSC@2 NA|NA|NA MAG.T2.42_03246 1142394.PSMK_14590 3.7e-78 298.5 Planctomycetes uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2J02W@203682,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin MAG.T2.42_03247 1123253.AUBD01000011_gene2025 8.5e-75 287.3 Xanthomonadales ilvC 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV7M@1224,1RNA8@1236,1X35R@135614,COG0059@1,COG0059@2 NA|NA|NA EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate MAG.T2.42_03250 1223410.KN050846_gene39 2.4e-12 80.1 Flavobacteriia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1IJKK@117743,4NQIZ@976,COG1404@1,COG1404@2,COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T2.42_03252 1122176.KB903542_gene405 1.1e-49 203.0 Bacteria ko:K07025 ko00000 Bacteria COG1011@1,COG1011@2 NA|NA|NA S phosphatase activity MAG.T2.42_03253 1380394.JADL01000004_gene5750 2.1e-30 139.0 Rhodospirillales ko:K09705 ko00000 Bacteria 1RAD7@1224,2JY7V@204441,2U6RX@28211,COG3542@1,COG3542@2 NA|NA|NA S Cupin superfamily (DUF985) MAG.T2.42_03254 391625.PPSIR1_22374 2.6e-85 322.8 Deltaproteobacteria ko:K03294,ko:K13868 ko04974,map04974 ko00000,ko00001,ko02000 2.A.3.2,2.A.3.8.15 Bacteria 1MXNJ@1224,2WSUN@28221,42MGQ@68525,COG0531@1,COG0531@2 NA|NA|NA E PFAM amino acid permease-associated region MAG.T2.42_03255 518766.Rmar_2175 5.5e-95 354.8 Bacteroidetes Order II. Incertae sedis gdh 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 1FIYD@1100069,4NGQH@976,COG4198@1,COG4198@2 NA|NA|NA S Protein of unknown function (DUF1015) MAG.T2.42_03256 1191523.MROS_0721 4.2e-92 345.1 Bacteria serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine MAG.T2.42_03257 64471.sync_0484 1.6e-37 162.5 Synechococcus ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1G5U8@1117,1H0MJ@1129,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MAG.T2.42_03258 1142394.PSMK_02400 6.4e-22 110.5 Planctomycetes ko:K06940 ko00000 Bacteria 2J0KU@203682,COG0727@1,COG0727@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0153) MAG.T2.42_03259 1142394.PSMK_24440 1.7e-229 802.4 Planctomycetes rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXGN@203682,COG0086@1,COG0086@2,COG2190@1,COG2190@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.42_03260 1379270.AUXF01000007_gene901 1.1e-70 274.2 Gemmatimonadetes fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1ZU8D@142182,COG2217@1,COG2217@2,COG2608@1,COG2608@2 NA|NA|NA P Putative metal-binding domain of cation transport ATPase MAG.T2.42_03262 314230.DSM3645_28142 4.6e-15 87.4 Planctomycetes Bacteria 2J4XX@203682,COG3316@1,COG3316@2 NA|NA|NA L IS66 C-terminal element MAG.T2.42_03263 1449976.KALB_5740 3.1e-42 178.7 Pseudonocardiales MA20_32325 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 2GMH2@201174,4DYSC@85010,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T2.42_03264 1142394.PSMK_13900 8e-22 110.9 Bacteria nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T2.42_03265 1142394.PSMK_13890 5.7e-12 77.8 Bacteria rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria COG0858@1,COG0858@2 NA|NA|NA J rRNA processing MAG.T2.42_03266 1142394.PSMK_13870 2.4e-125 455.7 Planctomycetes infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2IXYU@203682,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex MAG.T2.42_03270 595460.RRSWK_03471 4.5e-07 62.0 Planctomycetes GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 4.2.1.129,5.4.99.17,5.5.1.16 ko:K06045,ko:K17811 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2J1Q5@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase MAG.T2.42_03271 1123508.JH636440_gene2177 4.1e-35 155.2 Planctomycetes ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21030,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS20335 Bacteria 2IYXJ@203682,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) MAG.T2.42_03272 1121861.KB899911_gene1187 8.2e-112 410.6 Rhodospirillales prmA 2.1.1.222,2.1.1.64 ko:K00568,ko:K02687 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1RCZ3@1224,2JYC6@204441,2TZKH@28211,COG2264@1,COG2264@2 NA|NA|NA J Protein of unknown function (DUF1698) MAG.T2.42_03274 1348657.M622_05065 1.7e-50 206.1 Rhodocyclales Bacteria 1RAXF@1224,2KXH2@206389,2VY6I@28216,COG3381@1,COG3381@2 NA|NA|NA S Nitrate reductase delta subunit MAG.T2.42_03275 913325.N799_06630 4.9e-11 74.7 Xanthomonadales wzt 3.6.3.38 ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.103 Bacteria 1MWWC@1224,1RN2T@1236,1X3C5@135614,COG1134@1,COG1134@2 NA|NA|NA GM Wzt C-terminal domain MAG.T2.42_03276 1173027.Mic7113_5261 1.6e-32 147.1 Oscillatoriales Bacteria 1G9RY@1117,1HDSS@1150,COG2227@1,COG2227@2 NA|NA|NA H PFAM Methyltransferase MAG.T2.42_03277 1123508.JH636447_gene7762 9.9e-84 317.0 Planctomycetes desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2IZ45@203682,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase MAG.T2.42_03278 243090.RB10165 1e-99 370.5 Planctomycetes ko:K03932 ko00000 CE1 Bacteria 2IX6R@203682,COG1305@1,COG1305@2,COG3509@1,COG3509@2 NA|NA|NA Q depolymerase MAG.T2.42_03279 69042.WH5701_02174 1.3e-28 132.9 Bacteria Bacteria 2DGG3@1,32U75@2 NA|NA|NA MAG.T2.42_03280 1415780.JPOG01000001_gene64 5.5e-40 171.0 Gammaproteobacteria yuaD Bacteria 1RE2Q@1224,1SEFF@1236,COG2258@1,COG2258@2 NA|NA|NA S MOSC domain MAG.T2.42_03281 1121468.AUBR01000004_gene176 1.4e-38 167.2 Thermoanaerobacterales Bacteria 1TRQS@1239,24E3C@186801,42FVK@68295,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain MAG.T2.42_03282 1234364.AMSF01000005_gene806 5.3e-22 110.9 Xanthomonadales ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.21 ko:K00567,ko:K13529,ko:K13531 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1N2YQ@1224,1S68H@1236,1X6DF@135614,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated MAG.T2.42_03284 4533.OB12G19310.1 1.2e-09 70.9 Poales Viridiplantae 28ZS9@1,2R6KX@2759,3878K@33090,3GV84@35493,3INCB@38820,3M57G@4447 NA|NA|NA MAG.T2.42_03288 314230.DSM3645_06971 5.5e-80 303.9 Planctomycetes uxs 4.1.1.35,4.2.1.46 ko:K01710,ko:K08678 ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00793 R01384,R06513 RC00402,RC00508 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWW0@203682,COG0451@1,COG0451@2 NA|NA|NA GM NAD- dependent epimerase dehydratase MAG.T2.42_03291 502025.Hoch_5079 2.6e-07 62.4 Myxococcales Bacteria 1QVA0@1224,2WM47@28221,2YXTN@29,42P8X@68525,COG3203@1,COG3203@2 NA|NA|NA M SMART Integrin alpha beta-propellor repeat protein MAG.T2.42_03292 1194165.CAJF01000036_gene1702 1.4e-92 345.9 Microbacteriaceae oppD ko:K02031,ko:K02032,ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,4FQYT@85023,COG0444@1,COG0444@2 NA|NA|NA EP Oligopeptide/dipeptide transporter, C-terminal region MAG.T2.42_03293 279238.Saro_0379 8.7e-81 306.2 Sphingomonadales Bacteria 1R6DA@1224,28IUK@1,2K6QK@204457,2U2K0@28211,2Z8T9@2 NA|NA|NA MAG.T2.42_03294 279238.Saro_0378 2.5e-155 554.7 Sphingomonadales Bacteria 1PQ6C@1224,28IFN@1,2K0VI@204457,2U2GK@28211,2Z8HC@2 NA|NA|NA MAG.T2.42_03295 1128421.JAGA01000001_gene2399 8.1e-127 460.7 Bacteria fahA 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4620 Bacteria COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase MAG.T2.42_03296 204669.Acid345_2006 1.4e-55 223.4 Acidobacteriia hisZ 6.1.1.21 ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JMV1@204432,3Y4H5@57723,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase MAG.T2.42_03297 1382306.JNIM01000001_gene770 2.4e-63 248.8 Chloroflexi rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2G6EU@200795,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family MAG.T2.42_03298 936455.KI421499_gene689 2.1e-254 884.8 Bradyrhizobiaceae pgi 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUFP@1224,2TQKP@28211,3JWSI@41294,COG0166@1,COG0166@2 NA|NA|NA G Phosphoglucose isomerase MAG.T2.42_03301 1396141.BATP01000023_gene661 3.2e-84 318.9 Verrucomicrobiae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2ITTN@203494,46UTH@74201,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T2.42_03302 344747.PM8797T_27225 2.7e-18 99.8 Planctomycetes Bacteria 2EP6R@1,2J43T@203682,33GTH@2 NA|NA|NA MAG.T2.42_03305 1142394.PSMK_22930 1.5e-91 343.2 Planctomycetes fbpC 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 Bacteria 2IZ1J@203682,COG3842@1,COG3842@2 NA|NA|NA P PFAM ABC transporter MAG.T2.42_03306 13689.BV96_04376 3.6e-27 127.9 Sphingomonadales lagD ko:K02021,ko:K03497,ko:K06147,ko:K13409 ko02010,ko04626,map02010,map04626 M00339 ko00000,ko00001,ko00002,ko02000,ko02044,ko03000,ko03036,ko04812 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 1QUIQ@1224,2K7D6@204457,2TW5U@28211,COG0497@1,COG0497@2,COG2274@1,COG2274@2 NA|NA|NA LV DNA recombination MAG.T2.42_03307 497965.Cyan7822_3776 4.2e-09 70.1 Cyanothece Bacteria 1GBP2@1117,2EWXB@1,33Q8Q@2,3KJC6@43988 NA|NA|NA MAG.T2.42_03308 1142394.PSMK_07140 3.1e-68 265.0 Planctomycetes Bacteria 2IXXW@203682,COG1403@1,COG1403@2 NA|NA|NA L PFAM HNH endonuclease MAG.T2.42_03310 207559.Dde_2502 2.8e-32 145.2 Desulfovibrionales Bacteria 1REIP@1224,2MB4S@213115,2WNWG@28221,42S29@68525,COG4843@1,COG4843@2 NA|NA|NA S protein conserved in bacteria (DUF2179) MAG.T2.42_03311 240016.ABIZ01000001_gene2614 1.7e-14 87.4 Bacteria 3.1.4.3 ko:K01114,ko:K12287,ko:K15125,ko:K16191,ko:K20276 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,ko05133,map00562,map00564,map00565,map01100,map01110,map02024,map04919,map05133 R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko00536,ko01000,ko02000,ko02042,ko02044 1.B.6.1.3 Bacteria COG2373@1,COG2373@2,COG2885@1,COG2885@2,COG3210@1,COG3210@2,COG5563@1,COG5563@2 NA|NA|NA U Large extracellular alpha-helical protein MAG.T2.42_03312 1142394.PSMK_30190 5.2e-66 257.7 Planctomycetes bshB1 ko:K01463 ko00000,ko01000 Bacteria 2IZ0B@203682,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase MAG.T2.42_03313 102232.GLO73106DRAFT_00026910 1.3e-27 131.7 Cyanobacteria ko:K11016 ko03070,map03070 ko00000,ko00001,ko02042,ko02044 Bacteria 1GC1J@1117,COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG3291@1,COG3291@2 NA|NA|NA QU Polymorphic membrane protein, Chlamydia MAG.T2.42_03314 1144319.PMI16_00592 1.8e-111 409.5 Oxalobacteraceae Bacteria 1MVZN@1224,2WEEM@28216,477X8@75682,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T2.42_03315 237368.SCABRO_01642 2.1e-15 89.0 Planctomycetes hsp ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2J11X@203682,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T2.42_03320 1379270.AUXF01000006_gene68 6.2e-90 338.6 Gemmatimonadetes mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1ZSWM@142182,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity MAG.T2.42_03321 1205680.CAKO01000010_gene3775 2.6e-45 187.6 Rhodospirillales nuoD GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MVIN@1224,2JPC7@204441,2TQZ0@28211,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T2.42_03327 69279.BG36_04825 7.1e-40 169.9 Phyllobacteriaceae Bacteria 1REG3@1224,2U71R@28211,32ZUE@2,43QCA@69277,arCOG05205@1 NA|NA|NA MAG.T2.42_03328 864069.MicloDRAFT_00027330 2.1e-154 552.0 Methylobacteriaceae Bacteria 1JSGY@119045,1MUVI@1224,2TSA7@28211,COG3039@1,COG3039@2 NA|NA|NA L Transposase domain (DUF772) MAG.T2.42_03335 935567.JAES01000011_gene1096 7.9e-50 203.0 Xanthomonadales yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 ko:K15034 ko00000,ko03012 Bacteria 1RH75@1224,1S5YQ@1236,1X6MZ@135614,COG1186@1,COG1186@2 NA|NA|NA J Protein chain release factor B MAG.T2.42_03336 743721.Psesu_0133 8.8e-86 323.2 Xanthomonadales plsC2 Bacteria 1RJMS@1224,1S71V@1236,1X64J@135614,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T2.42_03337 1123320.KB889730_gene5868 5.1e-66 257.7 Actinobacteria Bacteria 2GJRT@201174,COG0546@1,COG0546@2 NA|NA|NA S hydrolase MAG.T2.42_03338 1437882.AZRU01000002_gene2391 4.7e-104 384.8 Pseudomonas aeruginosa group phnW GO:0003674,GO:0003824 2.6.1.37,3.11.1.1 ko:K03430,ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 R00747,R04152 RC00008,RC00062,RC00368 ko00000,ko00001,ko01000,ko01007 Bacteria 1MWHJ@1224,1RNNI@1236,1YF2A@136841,COG0075@1,COG0075@2 NA|NA|NA E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily MAG.T2.42_03339 716544.wcw_0790 3.2e-47 195.3 Chlamydiae rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192,2.1.1.224 ko:K06941,ko:K15632 ko00000,ko01000,ko01504,ko03009 Bacteria 2JFUQ@204428,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T2.42_03340 644968.DFW101_3416 8.5e-36 157.5 Desulfovibrionales modA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 ko:K02020 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria 1MVNA@1224,2M98T@213115,2WKJB@28221,42MZE@68525,COG0725@1,COG0725@2 NA|NA|NA P molybdenum ABC transporter, periplasmic MAG.T2.42_03345 298655.KI912267_gene7755 1.2e-122 446.8 Actinobacteria ko:K07133 ko00000 Bacteria 2GK1Q@201174,COG1373@1,COG1373@2 NA|NA|NA J Domain of unknown function (DUF4143) MAG.T2.42_03347 1449058.JQKT01000010_gene2060 1.4e-128 465.7 Microbacteriaceae rfbA ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 2GP5K@201174,4FMSK@85023,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter MAG.T2.42_03348 1123354.AUDR01000016_gene1414 6.7e-111 407.5 Hydrogenophilales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1KSJ0@119069,1MW4E@1224,2VHBY@28216,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T2.42_03349 1205680.CAKO01000040_gene653 3.4e-26 125.2 Rhodospirillales merA Bacteria 1MU2U@1224,2JPMT@204441,2TU0K@28211,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family MAG.T2.42_03350 1142394.PSMK_20510 3.3e-45 188.7 Planctomycetes ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2IYD7@203682,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits MAG.T2.42_03353 1142394.PSMK_27110 1.3e-33 151.0 Planctomycetes rbn GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07058 ko00000 Bacteria 2J0M6@203682,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB MAG.T2.42_03354 661478.OP10G_4048 7.2e-143 513.8 Bacteria 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA MAG.T2.42_03355 1123393.KB891317_gene2416 7e-71 273.9 Hydrogenophilales copB 3.6.3.4 ko:K01533 R00086 RC00002 ko00000,ko01000 3.A.3.5 Bacteria 1KSDX@119069,1MU08@1224,2VMF6@28216,COG2217@1,COG2217@2 NA|NA|NA P haloacid dehalogenase-like hydrolase MAG.T2.42_03356 365044.Pnap_1254 7.3e-11 73.2 Comamonadaceae Bacteria 1NGRW@1224,2DVDD@1,2VY85@28216,32UZ7@2,4AEXN@80864 NA|NA|NA S Protein of unknown function (DUF2933) MAG.T2.42_03357 158500.BV97_02960 7.7e-83 313.5 Sphingomonadales Bacteria 1MUBZ@1224,2K3T3@204457,2TQZQ@28211,COG2020@1,COG2020@2 NA|NA|NA O Isoprenylcysteine carboxyl methyltransferase MAG.T2.42_03358 1123242.JH636437_gene6004 4.6e-30 139.4 Planctomycetes Bacteria 2IYTT@203682,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T2.42_03359 1380355.JNIJ01000058_gene176 2e-267 927.9 Bradyrhizobiaceae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,2TQQA@28211,3JZM1@41294,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain MAG.T2.42_03360 344747.PM8797T_13922 3.8e-148 531.2 Planctomycetes tal 1.1.1.343,1.1.1.44,2.2.1.2 ko:K00033,ko:K00616 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00006,M00007 R01528,R01827,R10221 RC00001,RC00439,RC00539,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY2M@203682,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway MAG.T2.42_03364 864702.OsccyDRAFT_1522 4.2e-40 172.2 Oscillatoriales tnp Bacteria 1G4RX@1117,1HHM0@1150,COG3547@1,COG3547@2 NA|NA|NA L PFAM Transposase IS116 IS110 IS902 family MAG.T2.42_03365 243164.DET0166 4.8e-69 268.1 Dehalococcoidia ko:K07497 ko00000 Bacteria 2G8GQ@200795,34DDP@301297,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic region MAG.T2.42_03366 1379270.AUXF01000001_gene2374 3.8e-20 104.0 Gemmatimonadetes ko:K07483,ko:K07497 ko00000 Bacteria 1ZVAG@142182,COG2963@1,COG2963@2 NA|NA|NA L Transposase MAG.T2.42_03369 1142394.PSMK_24450 5.6e-103 380.6 Planctomycetes rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IXVZ@203682,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T2.42_03373 661478.OP10G_0834 5.3e-122 444.5 Bacteria Bacteria COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine MAG.T2.42_03374 1469613.JT55_09215 8.7e-186 656.4 Proteobacteria Bacteria 1QVDX@1224,COG3598@1,COG3598@2 NA|NA|NA L PFAM TOPRIM domain protein MAG.T2.42_03380 886293.Sinac_1701 5.7e-114 417.5 Planctomycetes Bacteria 2IYR5@203682,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase MAG.T2.42_03382 391616.OA238_c45480 3.4e-109 401.7 Alphaproteobacteria Bacteria 1R8M9@1224,2UI32@28211,COG3385@1,COG3385@2 NA|NA|NA L Transposase MAG.T2.42_03383 1142394.PSMK_02310 5.2e-50 204.5 Planctomycetes hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272,ko:K21345 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_0922 Bacteria 2IY6V@203682,COG0615@1,COG0615@2,COG2870@1,COG2870@2 NA|NA|NA H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose MAG.T2.42_03384 395494.Galf_2176 1.4e-116 426.4 Betaproteobacteria cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1MU08@1224,2VHKE@28216,COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase MAG.T2.42_03386 861299.J421_0560 1.2e-07 64.3 Gemmatimonadetes yjfP GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0034338,GO:0052689 ko:K06889 ko00000 Bacteria 1ZV0K@142182,COG1073@1,COG1073@2 NA|NA|NA S alpha beta MAG.T2.42_03387 756272.Plabr_2790 7.5e-106 390.6 Planctomycetes Bacteria 2IXN8@203682,COG1520@1,COG1520@2 NA|NA|NA S serine threonine protein kinase afsK MAG.T2.42_03389 1313172.YM304_15330 5.6e-63 248.1 Acidimicrobiia Bacteria 2GIZF@201174,4CNHH@84992,COG5001@1,COG5001@2 NA|NA|NA T Putative diguanylate phosphodiesterase MAG.T2.42_03393 1280948.HY36_13300 2e-08 64.3 Hyphomonadaceae cynT GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1NGFN@1224,2TRPD@28211,43XQ6@69657,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T2.42_03395 1449357.JQLK01000001_gene2096 1e-16 92.8 Deinococcus-Thermus ko:K07075 ko00000 Bacteria 1WKBN@1297,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T2.42_03397 529884.Rhola_00012660 5.8e-38 164.5 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HSNY@201174,4FPMD@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T2.42_03398 1194165.CAJF01000018_gene3579 3.6e-15 87.8 Microbacteriaceae Bacteria 2EQHU@1,2GS7Q@201174,33I3U@2,4FQ3G@85023 NA|NA|NA MAG.T2.42_03402 1122962.AULH01000008_gene2270 6.8e-100 370.5 Alphaproteobacteria Bacteria 1MXZ6@1224,28JVF@1,2TR1P@28211,2Z9KD@2 NA|NA|NA MAG.T2.42_03403 525897.Dbac_1474 1.9e-12 78.6 Desulfovibrionales Bacteria 1N6ZA@1224,2ME0Z@213115,2WRAZ@28221,42WEK@68525,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 MAG.T2.42_03405 1121091.AUMP01000024_gene3023 7.4e-09 66.6 Bacilli argH GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K00619,ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000 Bacteria 1V9RI@1239,4HK7W@91061,COG1246@1,COG1246@2 NA|NA|NA E Acetyltransferase (GNAT) domain MAG.T2.42_03406 1380390.JIAT01000014_gene6124 7.4e-49 200.3 Rubrobacteria cysM GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 ko:K01883,ko:K12339,ko:K21148 ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122 M00021,M00359,M00360 R00897,R03132,R03601,R03650,R04859,R10610 RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIXE@201174,4CPXX@84995,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme MAG.T2.42_03407 1033730.CAHG01000007_gene2775 6e-56 224.2 Propionibacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4DNFB@85009,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T2.42_03408 1446473.JHWH01000008_gene157 4.6e-23 113.6 Paracoccus attL 1.1.1.1 ko:K00001,ko:K19954 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MVPH@1224,2PWVE@265,2TSX8@28211,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase MAG.T2.42_03409 460265.Mnod_2072 6.7e-51 206.8 Methylobacteriaceae aspA 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 Bacteria 1JTKV@119045,1R9JY@1224,2TVZD@28211,COG1027@1,COG1027@2 NA|NA|NA E PFAM fumarate lyase MAG.T2.42_03411 626887.J057_17235 4.9e-24 117.1 Alteromonadaceae Bacteria 1MXUW@1224,1RRXK@1236,464KW@72275,COG3488@1,COG3488@2 NA|NA|NA C Di-haem oxidoreductase, putative peroxidase MAG.T2.42_03413 1313172.YM304_33140 2.1e-43 182.6 Acidimicrobiia 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 Bacteria 2GNKC@201174,4CN31@84992,COG1694@1,COG3956@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase domain MAG.T2.42_03414 526224.Bmur_2108 9.4e-22 109.8 Bacteria ko:K09922 ko00000 Bacteria COG3169@1,COG3169@2 NA|NA|NA S Protein conserved in bacteria MAG.T2.42_03416 1510531.JQJJ01000009_gene464 1.3e-34 151.8 Bradyrhizobiaceae MA20_24570 Bacteria 1N7JA@1224,2UBQW@28211,3JZD7@41294,COG5470@1,COG5470@2 NA|NA|NA S Domain of unknown function (DUF1330) MAG.T2.42_03418 1313172.YM304_25790 4.6e-20 104.8 Acidimicrobiia MA20_40105 6.2.1.7 ko:K15868 ko00121,map00121 ko00000,ko00001,ko01000 Bacteria 2GJAA@201174,4CP51@84992,COG0318@1,COG0318@2 NA|NA|NA IQ Protein synonym acyl-CoA synthetase MAG.T2.42_03420 1100720.ALKN01000033_gene631 1.7e-46 191.8 Comamonadaceae can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273,iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Bacteria 1NGFN@1224,2VIBS@28216,4AJ5V@80864,COG0288@1,COG0288@2 NA|NA|NA P Carbonic anhydrase MAG.T2.42_03424 1229780.BN381_310036 5e-15 86.7 Actinobacteria Bacteria 2IA3C@201174,COG4638@1,COG4638@2 NA|NA|NA P Rieske 2Fe-2S MAG.T2.42_03427 1429916.X566_22060 2.2e-53 214.9 Bradyrhizobiaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1RDFP@1224,2U71I@28211,3JSGD@41294,COG0691@1,COG0691@2 NA|NA|NA O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene MAG.T2.42_03428 880071.Fleli_2311 2.9e-13 82.0 Cytophagia Bacteria 47JSW@768503,4NEIE@976,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug # 2422 queries scanned # Total time (seconds): 32.7024979591 # Rate: 74.06 q/s