# emapper version: emapper-hotfix-numpy-69-gdd722db emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/emapper//MAG.T22.56/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/Bin_prokka//MAG.T22.56/MAG.T22.56.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/emapper//MAG.T22.56/MAG.T22.56 --usemem --override # time: Fri Aug 21 07:24:54 2026 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. MAG.T22.56_00001 1123248.KB893314_gene3699 3.1e-46 191.4 Sphingobacteriia Bacteria 1ITA8@117747,29AZZ@1,2ZXYX@2,4NP6M@976 NA|NA|NA MAG.T22.56_00002 1150600.ADIARSV_1116 1.1e-55 223.0 Sphingobacteriia yfiT Bacteria 1ISRY@117747,4NNQI@976,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T22.56_00003 1123248.KB893314_gene3481 1.9e-51 209.9 Sphingobacteriia Bacteria 1IT7E@117747,4NH7M@976,COG1566@1,COG1566@2 NA|NA|NA V Protein of unknown function (DUF3667) MAG.T22.56_00004 1123248.KB893314_gene3481 9e-54 217.6 Sphingobacteriia Bacteria 1IT7E@117747,4NH7M@976,COG1566@1,COG1566@2 NA|NA|NA V Protein of unknown function (DUF3667) MAG.T22.56_00005 700598.Niako_6249 3.8e-109 401.4 Sphingobacteriia Bacteria 1IQR6@117747,4NFNB@976,COG0330@1,COG0330@2 NA|NA|NA O COG0330 Membrane protease subunits stomatin prohibitin homologs MAG.T22.56_00006 1123248.KB893385_gene4857 1.6e-32 146.7 Bacteroidetes ybtA ko:K05372 ko00000,ko03000 Bacteria 4NEEQ@976,COG2207@1,COG2207@2 NA|NA|NA K transcriptional regulator (AraC family) MAG.T22.56_00007 700598.Niako_5655 9.5e-94 350.9 Sphingobacteriia cap Bacteria 1IPM6@117747,4NDZ0@976,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T22.56_00008 925409.KI911562_gene1048 4.3e-165 587.4 Sphingobacteriia korB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IZ5W@117747,4NIE0@976,COG1013@1,COG1013@2 NA|NA|NA C COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit MAG.T22.56_00009 714943.Mucpa_5874 6.1e-106 390.6 Sphingobacteriia murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_0547 Bacteria 1IPZH@117747,4NG1C@976,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis MAG.T22.56_00010 391587.KAOT1_19597 0.0 1174.1 Flavobacteriia cphA 6.3.2.13,6.3.2.29,6.3.2.30 ko:K01928,ko:K03802 ko00300,ko00550,map00300,map00550 R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1HXFG@117743,4NEDY@976,COG0189@1,COG0189@2,COG0769@1,COG0769@2 NA|NA|NA HJM cyanophycin synthetase MAG.T22.56_00011 1123248.KB893331_gene3789 1.7e-90 339.3 Sphingobacteriia cphB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0042802,GO:0042803,GO:0043170,GO:0044238,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.6 ko:K13282 R09722 RC00064,RC00141 ko00000,ko01000,ko01002 iJN678.slr2001 Bacteria 1IREV@117747,4NI55@976,COG4242@1,COG4242@2 NA|NA|NA PQ Belongs to the peptidase S51 family MAG.T22.56_00012 1430331.EP10_00650 2.5e-18 97.8 Firmicutes Bacteria 1W3D1@1239,2E3PF@1,32YMI@2 NA|NA|NA MAG.T22.56_00013 926549.KI421517_gene3965 2.4e-111 408.7 Cytophagia ybiK 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 47K5N@768503,4NF1U@976,COG1446@1,COG1446@2 NA|NA|NA E PFAM peptidase T2 asparaginase 2 MAG.T22.56_00014 485918.Cpin_0403 1.1e-309 1068.9 Sphingobacteriia gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 1IP1Y@117747,4NE0P@976,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T22.56_00015 929556.Solca_3150 1.6e-33 148.7 Bacteroidetes Bacteria 4NSDW@976,COG4551@1,COG4551@2 NA|NA|NA S Low molecular weight phosphotyrosine protein phosphatase MAG.T22.56_00016 485918.Cpin_0192 2.4e-26 125.6 Sphingobacteriia mreD Bacteria 1ISUS@117747,2AFDM@1,315DF@2,4NQ5K@976 NA|NA|NA S rod shape-determining protein MreD MAG.T22.56_00017 929556.Solca_0354 4.9e-45 188.3 Sphingobacteriia mreC ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1IPE1@117747,4NF14@976,COG1792@1,COG1792@2 NA|NA|NA M shape-determining protein MreC MAG.T22.56_00018 485918.Cpin_0194 6.7e-171 606.7 Sphingobacteriia mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1IPMZ@117747,4NETQ@976,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl MAG.T22.56_00019 761193.Runsl_4906 1.9e-26 125.9 Cytophagia ko:K17285 ko00000,ko04147 Bacteria 47QKC@768503,4NSVQ@976,COG5276@1,COG5276@2 NA|NA|NA S repeat protein MAG.T22.56_00020 700598.Niako_0209 3.7e-41 175.3 Sphingobacteriia Bacteria 1IQNH@117747,4NG4W@976,COG5276@1,COG5276@2 NA|NA|NA S LVIVD repeat MAG.T22.56_00021 1123248.KB893319_gene4078 4.8e-243 847.0 Sphingobacteriia carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0661 Bacteria 1INWJ@117747,4NEQ0@976,COG0458@1,COG0458@2 NA|NA|NA EF Carbamoyl-phosphate synthase MAG.T22.56_00022 269798.CHU_0571 2.1e-82 312.8 Cytophagia Bacteria 47MMD@768503,4NFSN@976,COG3081@1,COG3081@2 NA|NA|NA S 37-kD nucleoid-associated bacterial protein MAG.T22.56_00023 485918.Cpin_0066 7.4e-183 646.7 Sphingobacteriia 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1INR3@117747,4NHCA@976,COG0513@1,COG0513@2 NA|NA|NA L helicase superfamily c-terminal domain MAG.T22.56_00024 929703.KE386491_gene3605 2.4e-84 319.3 Cytophagia cdu2 Bacteria 47NVA@768503,4NK07@976,COG0025@1,COG0025@2 NA|NA|NA P PFAM sodium hydrogen exchanger MAG.T22.56_00025 485918.Cpin_6745 6.4e-28 131.3 Bacteroidetes Bacteria 2F6V5@1,33ZB9@2,4P45R@976 NA|NA|NA MAG.T22.56_00027 984262.SGRA_1777 4.8e-109 401.4 Sphingobacteriia 2.4.1.349 ko:K12994 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1ITGA@117747,4NETA@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 MAG.T22.56_00028 1168034.FH5T_06745 1.6e-72 280.4 Bacteroidia Bacteria 2G3BA@200643,4NPGZ@976,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T22.56_00029 743722.Sph21_1649 2e-148 531.9 Sphingobacteriia GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008 Bacteria 1IQIA@117747,4NFCN@976,COG0667@1,COG0667@2 NA|NA|NA C potassium channel beta subunit MAG.T22.56_00030 1123248.KB893348_gene137 7.2e-151 540.4 Sphingobacteriia gdh 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 1IRVU@117747,4NGQH@976,COG4198@1,COG4198@2 NA|NA|NA S Protein of unknown function (DUF1015) MAG.T22.56_00031 1270196.JCKI01000004_gene1157 1.2e-96 360.1 Sphingobacteriia serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1IP7N@117747,4NE06@976,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine MAG.T22.56_00032 1121870.AUAA01000010_gene1621 7.1e-56 223.8 Chryseobacterium YH67_14670 Bacteria 1I06H@117743,3HGSX@358033,4NR4F@976,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) MAG.T22.56_00033 1313421.JHBV01000021_gene4768 1.8e-44 186.8 Sphingobacteriia Bacteria 1J12Q@117747,28I9R@1,2Z8CE@2,4NE54@976 NA|NA|NA S Lipid A 3-O-deacylase (PagL) MAG.T22.56_00035 1123248.KB893319_gene4049 6.7e-182 643.7 Sphingobacteriia lutB ko:K18929 ko00000 Bacteria 1INSU@117747,4NEBT@976,COG1139@1,COG1139@2 NA|NA|NA C iron-sulfur cluster-binding protein MAG.T22.56_00036 1123248.KB893319_gene4048 3.7e-81 308.9 Sphingobacteriia Bacteria 1IS1E@117747,4NF79@976,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase MAG.T22.56_00037 1173020.Cha6605_0078 2e-28 132.9 Cyanobacteria Bacteria 1G6BQ@1117,COG3034@1,COG3034@2 NA|NA|NA S PFAM L,D-transpeptidase catalytic domain MAG.T22.56_00038 509635.N824_07895 1.3e-61 243.0 Sphingobacteriia sirR ko:K03709 ko00000,ko03000 Bacteria 1IRWI@117747,4NGUP@976,COG1321@1,COG1321@2 NA|NA|NA K Helix-turn-helix diphteria tox regulatory element MAG.T22.56_00039 485918.Cpin_0740 3.6e-51 208.0 Sphingobacteriia Bacteria 1IS0K@117747,28NIX@1,2ZBK6@2,4NMEI@976 NA|NA|NA S Protein of unknown function (DUF2480) MAG.T22.56_00040 1123248.KB893348_gene174 2.6e-124 453.0 Sphingobacteriia ppiD 5.2.1.8 ko:K01802,ko:K03769,ko:K03770 ko00000,ko01000,ko03110 Bacteria 1INT0@117747,4NDZZ@976,COG0760@1,COG0760@2 NA|NA|NA O peptidylprolyl isomerase MAG.T22.56_00041 700598.Niako_6341 2.3e-147 528.5 Sphingobacteriia nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919 Bacteria 1INZ3@117747,4NDVX@976,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate MAG.T22.56_00042 1408433.JHXV01000023_gene3302 1e-18 102.1 Cryomorphaceae ko:K03933 ko00000 AA10,CBM73 Bacteria 1ICPP@117743,2PBJ2@246874,4PBW3@976,COG3291@1,COG3291@2 NA|NA|NA S PA domain MAG.T22.56_00043 531844.FIC_00727 1.3e-147 530.0 Flavobacteriia Bacteria 1HYK7@117743,4NFMV@976,COG1574@1,COG1574@2 NA|NA|NA S metal-dependent hydrolase with the TIM-barrel fold MAG.T22.56_00044 485918.Cpin_0749 7.3e-272 943.0 Sphingobacteriia gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1INTV@117747,4NFNH@976,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 MAG.T22.56_00045 485918.Cpin_1022 3.7e-28 131.3 Sphingobacteriia recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1IT8A@117747,4NSAS@976,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity MAG.T22.56_00046 485918.Cpin_0222 6.9e-47 193.4 Sphingobacteriia apaG ko:K06195 ko00000 Bacteria 1ISSC@117747,4NNRA@976,COG2967@1,COG2967@2 NA|NA|NA P protein affecting Mg2 Co2 transport MAG.T22.56_00047 1121904.ARBP01000011_gene1488 7.3e-20 103.6 Cytophagia Bacteria 47RAX@768503,4NNMS@976,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain MAG.T22.56_00048 700598.Niako_6538 7.2e-285 986.1 Sphingobacteriia typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1IQXV@117747,4NDVM@976,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA MAG.T22.56_00049 694427.Palpr_2702 1.1e-30 139.4 Bacteroidia Bacteria 2FUH5@200643,4NUSE@976,COG2852@1,COG2852@2 NA|NA|NA S Protein of unknown function (DUF559) MAG.T22.56_00050 929713.NIASO_12890 1.3e-37 162.5 Sphingobacteriia hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 ko:K04762,ko:K06179,ko:K06180 ko00000,ko01000,ko03009,ko03110 Bacteria 1ISBI@117747,4NP8I@976,COG1188@1,COG1188@2 NA|NA|NA J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) MAG.T22.56_00052 700598.Niako_7055 2.1e-28 134.0 Sphingobacteriia Bacteria 1IZHZ@117747,2EU8C@1,33MQS@2,4NZBW@976 NA|NA|NA S Domain of unknown function (DUF4836) MAG.T22.56_00053 485918.Cpin_7301 4.7e-30 137.5 Sphingobacteriia Bacteria 1IU5E@117747,4PGRJ@976,COG0629@1,COG0629@2 NA|NA|NA L Domain of unknown function (DUF3127) MAG.T22.56_00055 471854.Dfer_0608 2.7e-26 125.6 Cytophagia comA ko:K07691,ko:K11624,ko:K14989 ko02020,ko02024,map02020,map02024 M00476,M00484,M00522 ko00000,ko00001,ko00002,ko02022 Bacteria 47W15@768503,4NM2A@976,COG2197@1,COG2197@2 NA|NA|NA K Two component transcriptional regulator, LuxR family MAG.T22.56_00056 272562.CA_C3391 2.4e-23 116.3 Clostridiaceae Bacteria 1V026@1239,24K7Y@186801,36VH5@31979,COG0642@1,COG2205@2 NA|NA|NA T N-terminal 7TM region of histidine kinase MAG.T22.56_00058 700598.Niako_6110 2.2e-25 122.5 Bacteroidetes Bacteria 2A7CX@1,334RT@2,4NVQR@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.56_00059 714943.Mucpa_2512 6.2e-82 310.8 Sphingobacteriia Bacteria 1IVKS@117747,2BKAK@1,32EQY@2,4NQPZ@976 NA|NA|NA MAG.T22.56_00060 925409.KI911562_gene2042 2.4e-87 328.9 Sphingobacteriia rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1IPJ5@117747,4NE1K@976,COG1234@1,COG1234@2 NA|NA|NA S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA MAG.T22.56_00061 929713.NIASO_18470 8.9e-12 76.6 Bacteria ko:K04749 ko00000,ko03021 Bacteria COG1366@1,COG1366@2 NA|NA|NA T antisigma factor binding MAG.T22.56_00062 485918.Cpin_6630 0.0 1329.7 Sphingobacteriia clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1IPYI@117747,4NE1J@976,COG0542@1,COG0542@2 NA|NA|NA O with chaperone activity ATP-binding subunit MAG.T22.56_00063 1454007.JAUG01000064_gene325 2.3e-67 263.1 Bacteroidetes Bacteria 4NGPJ@976,COG2234@1,COG2234@2 NA|NA|NA S PFAM Peptidase family M28 MAG.T22.56_00064 661367.LLO_1982 1.4e-243 849.0 Legionellales 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 1JFU3@118969,1MWYN@1224,1RS2Q@1236,COG1164@1,COG1164@2 NA|NA|NA E Angiotensin-converting enzyme MAG.T22.56_00066 1121373.KB903637_gene983 1.9e-133 482.3 Cytophagia asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1523 Bacteria 47JMK@768503,4NE4V@976,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate MAG.T22.56_00067 1313421.JHBV01000030_gene2067 1.8e-43 183.7 Bacteroidetes Bacteria 28PK5@1,2ZC9N@2,4NI1X@976 NA|NA|NA MAG.T22.56_00068 1408433.JHXV01000007_gene2926 9.3e-88 331.6 Cryomorphaceae ko:K16089 ko00000,ko02000 1.B.14.1,1.B.14.10 Bacteria 1HY46@117743,2PAD5@246874,4NET0@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug Domain MAG.T22.56_00069 485918.Cpin_5496 9.6e-181 640.2 Sphingobacteriia mdlA ko:K06147,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1IPDM@117747,4NDY6@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T22.56_00070 1492737.FEM08_02010 4.4e-24 118.2 Flavobacterium 3.1.4.58 ko:K01975 ko00000,ko01000,ko03016 Bacteria 1IC22@117743,2NTM5@237,4NTJ1@976,COG1514@1,COG1514@2 NA|NA|NA J 2',5' RNA ligase MAG.T22.56_00071 485918.Cpin_0600 1.3e-123 450.3 Sphingobacteriia Bacteria 1ISM5@117747,4NFZR@976,COG0265@1,COG0265@2,COG2234@1,COG2234@2 NA|NA|NA O Peptidase, M28 MAG.T22.56_00072 925409.KI911562_gene50 8.3e-61 240.4 Sphingobacteriia scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1IS83@117747,4NPG3@976,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves MAG.T22.56_00073 485918.Cpin_7006 5.6e-128 464.5 Sphingobacteriia nuoN 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1IP5V@117747,4NF94@976,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00074 485918.Cpin_7007 9.6e-147 526.9 Sphingobacteriia nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1IPJW@117747,4NEJ1@976,COG1008@1,COG1008@2 NA|NA|NA C proton-translocating NADH-quinone oxidoreductase, chain M MAG.T22.56_00075 485918.Cpin_7008 1.2e-229 802.7 Sphingobacteriia nuoL 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1IQ9D@117747,4NEBM@976,COG1009@1,COG1009@2 NA|NA|NA CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit MAG.T22.56_00076 485918.Cpin_7009 2.8e-32 144.4 Sphingobacteriia nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1ISXN@117747,4NTBP@976,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00077 485918.Cpin_7010 4.7e-48 197.6 Sphingobacteriia nuoJ 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1ISVB@117747,4NP2V@976,COG0839@1,COG0839@2 NA|NA|NA C Belongs to the complex I subunit 6 family MAG.T22.56_00078 700598.Niako_7070 2.9e-58 231.5 Sphingobacteriia nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00338,ko:K02573 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1IS7C@117747,4NI9I@976,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00079 714943.Mucpa_3123 2.1e-127 462.2 Sphingobacteriia nuoH 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1IR49@117747,4NGK7@976,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone MAG.T22.56_00080 1267211.KI669560_gene957 7.4e-168 596.7 Sphingobacteriia nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.12.1.2,1.12.1.3,1.17.1.9,1.6.5.3 ko:K00123,ko:K00184,ko:K00335,ko:K00336,ko:K18006,ko:K18332 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1,5.A.3 Bacteria 1IR1J@117747,4NH3P@976,COG1034@1,COG1034@2 NA|NA|NA C PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding MAG.T22.56_00081 925409.KI911562_gene208 1.8e-240 838.2 Sphingobacteriia nuoF 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1INS2@117747,4NFB5@976,COG1894@1,COG1894@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain MAG.T22.56_00082 504472.Slin_0455 3.1e-13 81.6 Cytophagia MA20_44825 Bacteria 47RCI@768503,4NSGY@976,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T22.56_00083 700598.Niako_7066 7.8e-72 276.6 Sphingobacteriia nuoE 1.6.5.3,1.6.99.3 ko:K00334,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 1IS1Q@117747,4NHIQ@976,COG1905@1,COG1905@2 NA|NA|NA C NADH-quinone oxidoreductase, E subunit MAG.T22.56_00084 700598.Niako_7065 1e-181 642.9 Sphingobacteriia nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1IR4T@117747,4NF02@976,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00085 1123248.KB893314_gene3401 5.2e-63 247.3 Sphingobacteriia ndhJ GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0050136,GO:0055114,GO:0071944 1.6.5.3 ko:K00332,ko:K05581,ko:K13378 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iJN678.ndhJ Bacteria 1ISEW@117747,4NPZH@976,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00086 1123248.KB893314_gene3402 5.3e-85 320.5 Sphingobacteriia ndhK 1.6.5.3 ko:K00331,ko:K05582 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iJN678.ndhK Bacteria 1INQ8@117747,4NFKT@976,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00087 1123248.KB893381_gene1013 5e-42 177.2 Sphingobacteriia nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1ISVI@117747,4NQJB@976,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T22.56_00088 1122176.KB903562_gene3445 6.1e-29 135.2 Bacteria Bacteria COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity MAG.T22.56_00089 700598.Niako_3019 1e-59 236.9 Bacteroidetes ubiE8 Bacteria 4NRXV@976,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain MAG.T22.56_00091 1144313.PMI10_03451 7.9e-153 547.4 Flavobacterium sulP Bacteria 1HYXB@117743,2NTIB@237,4NE9G@976,COG0659@1,COG0659@2 NA|NA|NA P Sulfate permease family MAG.T22.56_00092 1123248.KB893337_gene2374 2.3e-66 258.8 Sphingobacteriia cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1IP6Z@117747,4NH0X@976,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T22.56_00093 1122176.KB903551_gene4219 2.9e-33 149.4 Bacteria glsA 3.5.1.2 ko:K01425,ko:K13652 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000,ko03000 Bacteria COG3832@1,COG3832@2,COG4978@1,COG4978@2 NA|NA|NA J glyoxalase III activity MAG.T22.56_00094 700598.Niako_7047 1.3e-132 479.6 Sphingobacteriia rlmN 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 1IQMY@117747,4NFH5@976,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T22.56_00097 1121373.KB903632_gene586 1e-21 110.9 Cytophagia yrhL GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 Bacteria 47NBE@768503,4NPI2@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_00098 504472.Slin_3510 2.1e-19 101.3 Cytophagia Bacteria 47RTD@768503,4NSK5@976,COG3801@1,COG3801@2 NA|NA|NA S YjbR MAG.T22.56_00100 485917.Phep_1457 3.1e-25 120.9 Sphingobacteriia Bacteria 1ITIN@117747,2CUMY@1,32SVM@2,4NTF0@976 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.56_00101 391596.PBAL39_04748 4.1e-144 517.7 Sphingobacteriia fabH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IPRR@117747,4NEYH@976,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T22.56_00102 485918.Cpin_0870 1.2e-103 382.9 Sphingobacteriia Bacteria 1IPN9@117747,4NEAI@976,COG1028@1,COG1028@2 NA|NA|NA IQ COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) MAG.T22.56_00104 272559.BF9343_2888 1.3e-42 179.5 Bacteroidaceae Bacteria 2FSVY@200643,4ASQD@815,4NQJJ@976,COG4430@1,COG4430@2 NA|NA|NA S Domain of unknown function (DUF1905) MAG.T22.56_00105 1270196.JCKI01000005_gene2991 3e-19 101.7 Sphingobacteriia Bacteria 1IXV3@117747,2F4YB@1,33XK8@2,4P32D@976 NA|NA|NA MAG.T22.56_00107 421531.IX38_13185 9.9e-22 109.0 Chryseobacterium cspB ko:K03704 ko00000,ko03000 Bacteria 1I50Z@117743,3ZSRX@59732,4NURE@976,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain MAG.T22.56_00110 929562.Emtol_3498 3e-28 132.9 Cytophagia Bacteria 47JPN@768503,4NPI2@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_00112 485918.Cpin_3759 4e-112 411.4 Sphingobacteriia etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 ko:K03522 ko00000,ko04147 Bacteria 1IPHN@117747,4NFSE@976,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein MAG.T22.56_00113 1267211.KI669560_gene2219 8.6e-91 340.1 Sphingobacteriia etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K03521 ko00000 Bacteria 1IQTX@117747,4NFWB@976,COG2086@1,COG2086@2 NA|NA|NA C Electron transfer flavoprotein MAG.T22.56_00114 1267211.KI669560_gene1213 1e-67 263.5 Sphingobacteriia CP_0228 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPT2@117747,4NE36@976,COG1579@1,COG1579@2 NA|NA|NA S Zinc ribbon domain MAG.T22.56_00115 1168034.FH5T_05640 8.9e-113 413.7 Bacteroidia yqfO 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2FMW2@200643,4NF51@976,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family MAG.T22.56_00116 485918.Cpin_6931 9.1e-116 423.3 Sphingobacteriia folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQDT@117747,4NEJP@976,COG0190@1,COG0190@2 NA|NA|NA H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate MAG.T22.56_00117 485918.Cpin_6932 3.8e-78 297.7 Sphingobacteriia queE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 Bacteria 1IQ8P@117747,4NESC@976,COG0602@1,COG0602@2 NA|NA|NA H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds MAG.T22.56_00118 1122605.KB893646_gene227 2.3e-89 335.5 Sphingobacteriia uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 iYL1228.KPN_03461 Bacteria 1IPDJ@117747,4NGIZ@976,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin MAG.T22.56_00119 1216967.L100_10509 9.6e-24 116.3 Elizabethkingia Bacteria 1I2W4@117743,2BRNW@1,32KNH@2,34RH9@308865,4NQZJ@976 NA|NA|NA MAG.T22.56_00120 485918.Cpin_1259 6e-150 537.3 Sphingobacteriia ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 1INRN@117747,4NE8F@976,COG0686@1,COG0686@2 NA|NA|NA E alanine dehydrogenase MAG.T22.56_00121 485918.Cpin_0852 7.6e-179 633.6 Sphingobacteriia rpoN ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 1IQIK@117747,4NE5B@976,COG1508@1,COG1508@2 NA|NA|NA K RNA polymerase, sigma-54 factor MAG.T22.56_00123 485918.Cpin_0933 2.2e-65 255.4 Sphingobacteriia Bacteria 1IQ2V@117747,4NEPX@976,COG0727@1,COG0727@2 NA|NA|NA S Protein of unknown function (DUF3109) MAG.T22.56_00124 485918.Cpin_1048 4.4e-46 191.4 Sphingobacteriia Bacteria 1IRUD@117747,4NF8G@976,COG0517@1,COG0517@2 NA|NA|NA S CBS domain MAG.T22.56_00125 485918.Cpin_1047 6e-108 397.1 Sphingobacteriia ohpC 3.7.1.14 ko:K05714 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R02603,R06789 RC00752,RC00753,RC01337 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 1INU7@117747,4NF80@976,COG2267@1,COG2267@2 NA|NA|NA I Alpha beta hydrolase MAG.T22.56_00126 700598.Niako_6689 4.7e-269 933.7 Sphingobacteriia ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 Bacteria 1IQVN@117747,4NE63@976,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate MAG.T22.56_00127 760192.Halhy_3065 1.3e-58 234.2 Bacteroidetes ko:K16705 ko00000 Bacteria 4NMYT@976,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase MAG.T22.56_00128 1122176.KB903550_gene4325 2.7e-12 79.7 Sphingobacteriia 3.1.21.3 ko:K01153,ko:K05789,ko:K07011,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko01005,ko02000,ko02048 8.A.3.1 Bacteria 1IZTF@117747,4NWAG@976,COG3206@1,COG3206@2 NA|NA|NA M Chain length determinant protein MAG.T22.56_00129 700598.Niako_5744 1.9e-147 528.9 Sphingobacteriia prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02835,ko:K15034 ko00000,ko03012 Bacteria 1IPKJ@117747,4NF72@976,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA MAG.T22.56_00130 1121957.ATVL01000011_gene3930 7.7e-47 194.9 Bacteroidetes Bacteria 2F9D3@1,341PZ@2,4P3ZH@976 NA|NA|NA MAG.T22.56_00131 1267211.KI669560_gene653 6.2e-284 983.8 Sphingobacteriia infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1IQ0V@117747,4NGP3@976,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex MAG.T22.56_00132 485918.Cpin_0652 9.7e-188 662.9 Sphingobacteriia nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 1IQJC@117747,4NFGA@976,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination MAG.T22.56_00133 925409.KI911562_gene648 8.8e-30 136.7 Sphingobacteriia rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1ISSY@117747,4NQ32@976,COG0779@1,COG0779@2 NA|NA|NA S Required for maturation of 30S ribosomal subunits MAG.T22.56_00135 485918.Cpin_0647 1.6e-58 232.6 Sphingobacteriia yihX 3.1.3.10,3.8.1.2 ko:K01560,ko:K07025,ko:K20866 ko00010,ko00361,ko00625,ko01100,ko01120,map00010,map00361,map00625,map01100,map01120 R00947,R05287 RC00078,RC00697 ko00000,ko00001,ko01000 Bacteria 1IS3Y@117747,4NQT8@976,COG1011@1,COG1011@2 NA|NA|NA S HAD-superfamily hydrolase subfamily IA, variant 3 MAG.T22.56_00138 760192.Halhy_2725 6.7e-113 414.1 Sphingobacteriia coaB 4.1.1.36,6.3.2.5 ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPJR@117747,4NE46@976,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine MAG.T22.56_00139 1123248.KB893348_gene249 3.5e-70 271.9 Sphingobacteriia Bacteria 1IPUY@117747,28HA8@1,2Z7MQ@2,4NEJD@976 NA|NA|NA S Domain of unknown function (DUF4835) MAG.T22.56_00140 468059.AUHA01000005_gene2573 2.6e-10 71.6 Bacteroidetes Bacteria 2EK3P@1,33DU3@2,4NXK2@976 NA|NA|NA S Domain of unknown function (DUF4296) MAG.T22.56_00141 485918.Cpin_6257 1.1e-148 533.1 Sphingobacteriia aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1INY0@117747,4NENS@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.56_00142 153721.MYP_3944 6.4e-32 144.1 Cytophagia ko:K03413 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 47XYH@768503,4PKPV@976,COG2204@1,COG2204@2 NA|NA|NA T cheY-homologous receiver domain MAG.T22.56_00143 153721.MYP_3945 1.7e-101 377.5 Cytophagia Bacteria 47JK3@768503,4NDXU@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_00145 1122605.KB893646_gene134 2e-20 105.1 Bacteroidetes Bacteria 2ECRS@1,336PE@2,4NV6F@976 NA|NA|NA MAG.T22.56_00146 313606.M23134_07726 1.6e-144 520.4 Cytophagia glgE 2.4.1.18,2.4.99.16 ko:K00700,ko:K07214,ko:K16147 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110,R09994 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 47PGJ@768503,4NEZQ@976,COG0296@1,COG0296@2,COG1372@1,COG1372@2,COG1404@1,COG1404@2,COG4447@1,COG4447@2 NA|NA|NA G Participates in initiation and elongation during chromosome replication MAG.T22.56_00147 857087.Metme_0482 2.5e-21 108.6 Methylococcales rlpA ko:K03642 ko00000 Bacteria 1MZ8S@1224,1S9P2@1236,1XGYG@135618,COG0797@1,COG0797@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides MAG.T22.56_00148 1123248.KB893317_gene4326 6.3e-153 547.7 Sphingobacteriia deaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1IQEP@117747,4NEJV@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.56_00150 1121930.AQXG01000011_gene1757 5.6e-33 147.1 Sphingobacteriia ko:K06996 ko00000 Bacteria 1IZ1H@117747,4NTUQ@976,COG3324@1,COG3324@2 NA|NA|NA S Glyoxalase-like domain MAG.T22.56_00152 1267211.KI669560_gene1854 1.8e-172 612.1 Sphingobacteriia bcd 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 Bacteria 1IPN4@117747,4NEHA@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.56_00153 1121899.Q764_10105 2.6e-47 195.3 Flavobacterium 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1I4ZE@117743,2NW48@237,4NUC3@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_00155 1191523.MROS_1352 4.3e-51 208.0 Bacteria Bacteria COG2353@1,COG2353@2 NA|NA|NA O YceI-like domain MAG.T22.56_00156 1124780.ANNU01000020_gene3311 9.6e-38 163.3 Cytophagia paiA Bacteria 47QAW@768503,4NQVT@976,COG0454@1,COG0456@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase MAG.T22.56_00157 700598.Niako_5113 1.5e-109 403.7 Sphingobacteriia ko:K03286 ko00000,ko02000 1.B.6 Bacteria 1IXGD@117747,4NIV8@976,COG2885@1,COG2885@2 NA|NA|NA M OmpA MotB domain protein MAG.T22.56_00158 485918.Cpin_6988 4e-117 427.9 Sphingobacteriia ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 iYL1228.KPN_03597,ic_1306.c3945 Bacteria 1INM5@117747,4NET2@976,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T22.56_00159 485918.Cpin_0158 0.0 1421.4 Sphingobacteriia uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1INYW@117747,4NFQU@976,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T22.56_00160 316274.Haur_1970 5.3e-136 491.9 Bacteria Bacteria COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T22.56_00161 485918.Cpin_1261 1.5e-193 682.9 Sphingobacteriia copA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1IPEH@117747,4NERS@976,COG2217@1,COG2217@2 NA|NA|NA P ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter MAG.T22.56_00162 1123248.KB893331_gene3798 1.3e-31 142.9 Sphingobacteriia yjeE 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1ITMH@117747,4NS89@976,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE MAG.T22.56_00163 485918.Cpin_1030 8e-38 164.1 Sphingobacteriia Bacteria 1ITSR@117747,4NH3F@976,COG1280@1,COG1280@2 NA|NA|NA E Lysine exporter protein (Lyse ygga) MAG.T22.56_00164 485918.Cpin_0655 8.3e-236 823.2 Sphingobacteriia purF 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1INR4@117747,4NFSM@976,COG0034@1,COG0034@2 NA|NA|NA F Amidophosphoribosyltransferase MAG.T22.56_00166 269798.CHU_1442 1.1e-267 929.9 Cytophagia 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 47JGQ@768503,4NEXH@976,COG0308@1,COG0308@2 NA|NA|NA E PFAM Peptidase M1, membrane alanine aminopeptidase MAG.T22.56_00168 485918.Cpin_5443 3.2e-37 161.8 Sphingobacteriia ko:K03088,ko:K03091 ko00000,ko03021 Bacteria 1IRWR@117747,4NNEM@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_00170 1189619.pgond44_09711 1.2e-18 99.4 Psychroflexus pimB GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 ko:K13668 R11703,R11704 ko00000,ko01000,ko01003 GT4 Bacteria 1HZ9H@117743,4C45M@83612,4NI57@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain MAG.T22.56_00171 746697.Aeqsu_2253 1.2e-96 360.1 Flavobacteriia Bacteria 1HX83@117743,4NE53@976,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase MAG.T22.56_00173 1305737.JAFX01000001_gene1733 1.4e-42 180.3 Bacteroidetes Bacteria 4NGIS@976,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase MAG.T22.56_00174 1484460.JSWG01000001_gene2337 2.5e-51 209.5 Flavobacteriia 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1HWZH@117743,4NE0U@976,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 MAG.T22.56_00175 443144.GM21_2454 7.3e-67 261.5 Desulfuromonadales 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1MV1W@1224,2WMGG@28221,42PY9@68525,43VMS@69541,COG1541@1,COG1541@2 NA|NA|NA H coenzyme F390 MAG.T22.56_00176 485918.Cpin_4757 1.2e-109 403.3 Sphingobacteriia wecB 5.1.3.14,5.1.3.23 ko:K01791,ko:K13019 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R09600 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IR9A@117747,4NGBD@976,COG0381@1,COG0381@2 NA|NA|NA M Belongs to the UDP-N-acetylglucosamine 2-epimerase family MAG.T22.56_00177 1211817.CCAT010000083_gene1670 2.1e-94 352.8 Clostridiaceae ko:K00786 ko00000,ko01000 Bacteria 1UTQH@1239,24BT3@186801,36F7W@31979,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 MAG.T22.56_00178 243265.plu4833 1.2e-30 140.2 Bacteria cheW-3 2.1.1.80,3.1.1.61 ko:K00575,ko:K03408,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria COG1352@1,COG1352@2 NA|NA|NA NT protein-glutamate O-methyltransferase activity MAG.T22.56_00179 1218103.CIN01S_09_01820 1.7e-129 469.2 Chryseobacterium bplA 1.1.1.335 ko:K13020 ko00520,map00520 R10140 RC00182 ko00000,ko00001,ko01000,ko01005 Bacteria 1I19J@117743,3ZQE3@59732,4NFY3@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T22.56_00180 1338011.BD94_3278 3.3e-140 505.0 Elizabethkingia spsC 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1HZBY@117743,34S0K@308865,4NFQ8@976,COG0399@1,COG0399@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T22.56_00181 862965.PARA_02750 1.2e-58 233.0 Pasteurellales bplG Bacteria 1MV6W@1224,1RMMN@1236,1YABV@135625,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase MAG.T22.56_00182 485918.Cpin_4766 1.3e-199 703.0 Sphingobacteriia capD 4.2.1.115,4.2.1.46,5.1.3.2 ko:K01710,ko:K15894,ko:K17716 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00362,M00793 R00291,R06513,R09697 RC00289,RC00402,RC02609 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPH4@117747,4NERY@976,COG1086@1,COG1086@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T22.56_00183 485918.Cpin_1188 6.5e-58 231.9 Sphingobacteriia envC Bacteria 1INMH@117747,4NH2T@976,COG4942@1,COG4942@2 NA|NA|NA D Peptidase, M23 MAG.T22.56_00184 485918.Cpin_0676 2.5e-81 308.9 Sphingobacteriia yicC ko:K03316 ko00000 2.A.36 Bacteria 1IQ8K@117747,4NEU4@976,COG1561@1,COG1561@2 NA|NA|NA S PFAM YicC-like family, N-terminal region MAG.T22.56_00185 485918.Cpin_0675 1.5e-27 129.4 Sphingobacteriia gldH GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 Bacteria 1IU3P@117747,2ADSH@1,313I2@2,4NQMU@976 NA|NA|NA S GldH lipoprotein MAG.T22.56_00186 485918.Cpin_0674 5.2e-72 278.1 Sphingobacteriia Bacteria 1IPNM@117747,4NK58@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_00187 925409.KI911562_gene1052 7.1e-65 253.8 Sphingobacteriia rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1IRYD@117747,4NGVR@976,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T22.56_00189 929713.NIASO_09650 1.7e-14 86.7 Sphingobacteriia Bacteria 1IU0Y@117747,2C9VJ@1,335CM@2,4NVB2@976 NA|NA|NA MAG.T22.56_00190 485918.Cpin_7230 1.8e-131 475.7 Sphingobacteriia pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 Bacteria 1IPRM@117747,4NDVB@976,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor MAG.T22.56_00191 1123248.KB893322_gene607 2.6e-93 348.6 Sphingobacteriia ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1J0BP@117747,4NH6F@976,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family MAG.T22.56_00193 755732.Fluta_0998 4.7e-10 72.8 Bacteroidetes 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 4NRDA@976,COG3209@1,COG3209@2 NA|NA|NA M COG3209 Rhs family protein MAG.T22.56_00198 1313421.JHBV01000028_gene1857 5.8e-101 376.3 Bacteroidetes ko:K12287 ko00000,ko02044 Bacteria 4NJ47@976,COG1357@1,COG1357@2,COG1404@1,COG1404@2,COG3291@1,COG3291@2 NA|NA|NA U PFAM PKD domain MAG.T22.56_00199 929556.Solca_3152 9.8e-220 769.6 Sphingobacteriia fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IWIB@117747,4NG3E@976,COG2759@1,COG2759@2 NA|NA|NA F Formate--tetrahydrofolate ligase MAG.T22.56_00201 929556.Solca_1252 4e-42 177.6 Sphingobacteriia Bacteria 1ITS0@117747,2D0TH@1,32T97@2,4NQFA@976 NA|NA|NA MAG.T22.56_00202 485918.Cpin_1250 3e-109 401.7 Sphingobacteriia yneE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08994 ko00000,ko02000 1.A.46.2 Bacteria 1IPZA@117747,4NIC7@976,COG3781@1,COG3781@2 NA|NA|NA S membrane MAG.T22.56_00203 485918.Cpin_1249 7e-18 97.4 Sphingobacteriia ko:K11932 ko00000 Bacteria 1IU8F@117747,4NW6X@976,COG0589@1,COG0589@2 NA|NA|NA T response to stress MAG.T22.56_00204 485918.Cpin_1248 3.2e-115 422.2 Sphingobacteriia Bacteria 1INVU@117747,4NEIS@976,COG0642@1,COG2205@2,COG5000@1,COG5000@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_00205 485918.Cpin_1247 4.9e-72 277.7 Sphingobacteriia Bacteria 1IRU7@117747,4NHXA@976,COG0745@1,COG0745@2 NA|NA|NA K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain MAG.T22.56_00206 925409.KI911562_gene1443 1.4e-40 173.3 Sphingobacteriia lolE ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 Bacteria 1IPJE@117747,4NG04@976,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component MAG.T22.56_00207 485918.Cpin_6433 6.9e-203 713.8 Sphingobacteriia argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1IQGR@117747,4NE7Q@976,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase MAG.T22.56_00208 485918.Cpin_6518 3.8e-28 130.6 Sphingobacteriia rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISVD@117747,4NS7U@976,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome MAG.T22.56_00209 485918.Cpin_6517 5.2e-307 1060.1 Sphingobacteriia pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1INMK@117747,4NE4Q@976,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction MAG.T22.56_00211 1296416.JACB01000017_gene5123 1e-54 221.5 Flavobacteriia Bacteria 1HX4T@117743,4NI65@976,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.56_00212 153721.MYP_1722 8e-29 133.3 Bacteroidetes Bacteria 33816@2,4NUVH@976,COG2259@1 NA|NA|NA S DoxX-like family MAG.T22.56_00213 1434325.AZQN01000004_gene1771 5.4e-33 147.1 Cytophagia Bacteria 47XUK@768503,4NQ2K@976,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix MAG.T22.56_00214 1121324.CLIT_2c00560 8.9e-36 157.1 Clostridia 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1TVX4@1239,25CSK@186801,COG1647@1,COG1647@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.56_00215 1406840.Q763_15120 3.5e-14 85.1 Flavobacteriia Bacteria 1I227@117743,2A5ZF@1,30URM@2,4NP1P@976 NA|NA|NA MAG.T22.56_00216 1123248.KB893348_gene340 5.9e-123 447.6 Sphingobacteriia Bacteria 1IQP5@117747,4NETA@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 MAG.T22.56_00217 1122605.KB893626_gene2493 1.9e-205 722.2 Bacteroidetes crtI 1.3.99.23,5.2.1.13 ko:K09516,ko:K09835 ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110 M00097 R07163,R07512 RC01835,RC01960 ko00000,ko00001,ko00002,ko01000 Bacteria 4P24Z@976,COG1233@1,COG1233@2 NA|NA|NA Q FAD binding domain MAG.T22.56_00218 700598.Niako_4947 4.9e-65 254.2 Sphingobacteriia ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 iYO844.BSU23270 Bacteria 1IPZJ@117747,4NHI8@976,COG0307@1,COG0307@2 NA|NA|NA H riboflavin synthase, alpha subunit MAG.T22.56_00220 485918.Cpin_1697 4.1e-21 106.7 Sphingobacteriia rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IU0K@117747,4NUPV@976,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family MAG.T22.56_00221 700598.Niako_4945 7.4e-76 290.8 Sphingobacteriia xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1IP2Y@117747,4NGQW@976,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family. XerC subfamily MAG.T22.56_00222 485918.Cpin_1699 6.2e-32 143.3 Sphingobacteriia hpf ko:K03733,ko:K05808,ko:K05809 ko00000,ko03009,ko03036 Bacteria 1ITNJ@117747,4NUME@976,COG1544@1,COG1544@2 NA|NA|NA J PFAM Sigma 54 modulation protein S30EA ribosomal protein MAG.T22.56_00223 8469.XP_007071171.1 1.9e-09 70.5 Testudines AASDH GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006518,GO:0006520,GO:0006629,GO:0006631,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016877,GO:0016878,GO:0019184,GO:0019482,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0043038,GO:0043041,GO:0043043,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576 ko:K00142 ko00000,ko01000,ko01004 Metazoa 38HGX@33154,3BC5T@33208,3CRUU@33213,4822K@7711,48ZYN@7742,4CK7K@8459,COG1020@1,COG1520@1,KOG1178@2759,KOG4649@2759 NA|NA|NA Q PQQ-like domain MAG.T22.56_00224 485918.Cpin_7185 1.3e-63 249.2 Sphingobacteriia ftnA 1.16.3.2 ko:K02217 ko00000,ko01000 Bacteria 1ITKI@117747,4NGS7@976,COG1528@1,COG1528@2 NA|NA|NA P Iron-storage protein MAG.T22.56_00225 626522.GCWU000325_02421 5.3e-28 131.0 Alloprevotella Bacteria 1WDBY@1283313,2FSTK@200643,4NNHX@976,COG0526@1,COG0526@2 NA|NA|NA O Thioredoxin-like MAG.T22.56_00226 1122176.KB903573_gene4827 3.2e-127 462.2 Bacteroidetes Bacteria 2CIBF@1,2Z85N@2,4NF0J@976 NA|NA|NA MAG.T22.56_00227 1267211.KI669560_gene69 3.6e-235 820.8 Sphingobacteriia nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 Bacteria 1IQPX@117747,4NGUE@976,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate MAG.T22.56_00228 1122179.KB890425_gene3428 2.2e-58 233.8 Bacteroidetes Bacteria 4PPF8@976,COG1404@1,COG1404@2,COG2356@1,COG2356@2,COG3291@1,COG3291@2 NA|NA|NA O Reprolysin (M12B) family zinc metalloprotease MAG.T22.56_00229 1121481.AUAS01000002_gene3178 1.1e-245 855.9 Cytophagia msbA ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 47K10@768503,4NEBS@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T22.56_00231 573061.Clocel_0284 3e-63 248.8 Bacteria Bacteria 335UQ@2,arCOG06802@1 NA|NA|NA MAG.T22.56_00234 485918.Cpin_5457 4.2e-14 84.0 Bacteria Bacteria COG5512@1,COG5512@2 NA|NA|NA L Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives MAG.T22.56_00235 929713.NIASO_14820 2e-65 255.8 Sphingobacteriia ko:K07025 ko00000 Bacteria 1J0KR@117747,4PM7Q@976,COG0546@1,COG0546@2 NA|NA|NA S HAD-hyrolase-like MAG.T22.56_00236 485918.Cpin_6967 3.6e-33 147.5 Sphingobacteriia rpoZ Bacteria 1ISVJ@117747,2CT4B@1,32SSJ@2,4NQ76@976 NA|NA|NA K RNA polymerase MAG.T22.56_00237 485918.Cpin_6968 6.8e-57 227.6 Sphingobacteriia yfiO ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria 1IPXN@117747,4NJ5A@976,COG4105@1,COG4105@2 NA|NA|NA S outer membrane assembly lipoprotein YfiO MAG.T22.56_00238 485918.Cpin_6970 3.4e-45 188.0 Sphingobacteriia mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1IS84@117747,4NM4X@976,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family MAG.T22.56_00239 700598.Niako_7316 1.9e-100 372.5 Sphingobacteriia rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1INNA@117747,4NFQB@976,COG0275@1,COG0275@2 NA|NA|NA M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA MAG.T22.56_00240 485918.Cpin_6972 6.3e-10 70.5 Sphingobacteriia Bacteria 1ITPF@117747,2ADW0@1,313N0@2,4NSUW@976 NA|NA|NA MAG.T22.56_00241 485918.Cpin_6973 1.6e-171 609.8 Sphingobacteriia ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 2.7.11.1,3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12132,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01001,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1IQ79@117747,4NERV@976,COG0768@1,COG0768@2,COG2815@1,COG2815@2 NA|NA|NA M Cell division protein FtsI penicillin-binding protein 2 MAG.T22.56_00242 485918.Cpin_6974 3.4e-176 624.8 Sphingobacteriia murE 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1INW4@117747,4NE9W@976,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T22.56_00243 485918.Cpin_0535 9e-48 196.8 Sphingobacteriia Bacteria 1ISSQ@117747,2DEYG@1,2ZPSM@2,4NNJW@976 NA|NA|NA MAG.T22.56_00244 485918.Cpin_0723 6.1e-136 491.1 Sphingobacteriia yngK2 Bacteria 1IP9B@117747,4NFKQ@976,COG1649@1,COG1649@2 NA|NA|NA S PFAM Uncharacterised BCR, COG1649 MAG.T22.56_00246 485918.Cpin_1669 3.4e-64 252.7 Sphingobacteriia Bacteria 1IPQK@117747,4NG1I@976,COG0457@1,COG0457@2 NA|NA|NA S PFAM Tetratricopeptide repeat MAG.T22.56_00247 925409.KI911562_gene305 1.1e-293 1015.4 Sphingobacteriia korA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IYHV@117747,4NEP3@976,COG0674@1,COG0674@2,COG1014@1,COG1014@2 NA|NA|NA C PFAM Pyruvate flavodoxin ferredoxin oxidoreductase MAG.T22.56_00249 1124780.ANNU01000023_gene3157 9.3e-33 148.7 Cytophagia ywmD ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 47MRQ@768503,4NJF1@976,COG2304@1,COG2304@2 NA|NA|NA S PFAM von Willebrand factor type A domain MAG.T22.56_00250 1284352.AOIG01000007_gene2171 8.8e-27 126.7 Paenibacillaceae Bacteria 1VEHB@1239,26ZP3@186822,4HQT2@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.56_00251 1353276.JADR01000002_gene2215 4e-26 125.9 Flavobacteriia bioF2 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1I0KW@117743,4NI7H@976,COG3146@1,COG3146@2 NA|NA|NA S 8-amino-7-oxononanoate synthase MAG.T22.56_00252 926562.Oweho_0906 2.7e-30 140.2 Cryomorphaceae Bacteria 1I9QR@117743,2PBG1@246874,4NYPX@976,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T22.56_00253 700598.Niako_6289 0.0 1280.0 Sphingobacteriia polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1IPFU@117747,4NDVA@976,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity MAG.T22.56_00254 1267211.KI669560_gene2053 1.9e-41 175.6 Bacteroidetes IV02_27370 ko:K06940 ko00000 Bacteria 4NJH9@976,COG0727@1,COG0727@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0153) MAG.T22.56_00255 700598.Niako_5667 8.6e-183 647.5 Sphingobacteriia Bacteria 1IPK5@117747,4NDYT@976,COG4775@1,COG4775@2 NA|NA|NA M CarboxypepD_reg-like domain MAG.T22.56_00256 1124780.ANNU01000023_gene3159 7.3e-48 196.8 Cytophagia bcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 47PUA@768503,4NNGK@976,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.56_00257 485918.Cpin_1179 8.2e-134 484.2 Sphingobacteriia Bacteria 1INUW@117747,4NED7@976,COG0739@1,COG0739@2 NA|NA|NA M Peptidase, M23 MAG.T22.56_00259 485918.Cpin_0462 3.4e-47 195.3 Sphingobacteriia recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1IS4Q@117747,4NIBQ@976,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination MAG.T22.56_00260 700598.Niako_5741 6.2e-132 478.4 Sphingobacteriia Bacteria 1IVTD@117747,4NDWE@976,COG3292@1,COG3292@2 NA|NA|NA T Two component regulator propeller domain protein MAG.T22.56_00261 485917.Phep_3338 3.8e-22 111.7 Sphingobacteriia Bacteria 1IUGR@117747,2DPSB@1,33369@2,4NW9H@976 NA|NA|NA S Transmembrane exosortase (Exosortase_EpsH) MAG.T22.56_00262 485918.Cpin_0883 2.6e-96 358.6 Sphingobacteriia tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1IP5Z@117747,4NF03@976,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome MAG.T22.56_00263 485918.Cpin_0882 1.3e-107 396.4 Sphingobacteriia rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IQSP@117747,4NER0@976,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family MAG.T22.56_00264 485918.Cpin_0881 1.1e-44 186.0 Sphingobacteriia rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISJG@117747,4NNN1@976,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family MAG.T22.56_00265 485918.Cpin_0880 7.8e-55 219.9 Sphingobacteriia rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IS32@117747,4NNGA@976,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly MAG.T22.56_00266 1492737.FEM08_16180 5.5e-25 120.2 Flavobacterium Bacteria 1IN0S@117743,2EM7W@1,2NWXW@237,33EX0@2,4P5SH@976 NA|NA|NA MAG.T22.56_00267 1185876.BN8_04846 7.3e-83 314.7 Cytophagia 3.6.4.12 ko:K17680 ko00000,ko01000,ko03029 Bacteria 47NER@768503,4NETK@976,COG0358@1,COG0358@2 NA|NA|NA L Protein of unknown function (DUF3987) MAG.T22.56_00268 1123276.KB893263_gene4653 6e-51 208.0 Bacteroidetes Bacteria 4NRDJ@976,COG5545@1,COG5545@2 NA|NA|NA L VirE N-terminal domain MAG.T22.56_00269 926559.JoomaDRAFT_1427 6.9e-155 553.5 Flavobacteriia dcm 2.1.1.37 ko:K00558,ko:K13639,ko:K13640 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03000,ko03032,ko03036 Bacteria 1HZAK@117743,4NG9A@976,COG0270@1,COG0270@2,COG0789@1,COG0789@2 NA|NA|NA H cytosine-specific methyltransferase MAG.T22.56_00270 1189612.A33Q_2749 4.4e-68 264.6 Cytophagia 3.1.21.4 ko:K01155 ko00000,ko01000,ko02048 Bacteria 2CJP6@1,2Z7MS@2,47SIS@768503,4NJDB@976 NA|NA|NA L Eco47II restriction endonuclease MAG.T22.56_00271 485918.Cpin_1855 7.2e-170 603.6 Sphingobacteriia fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Bacteria 1IR9V@117747,4NFBN@976,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T22.56_00272 118163.Ple7327_2878 2.6e-22 113.6 Pleurocapsales Bacteria 1G2Q6@1117,28N8A@1,2ZBCR@2,3VMJF@52604 NA|NA|NA MAG.T22.56_00273 485917.Phep_3759 2.3e-131 475.3 Sphingobacteriia Bacteria 1IP0J@117747,4NGSR@976,COG4977@1,COG4977@2 NA|NA|NA K DJ-1/PfpI family MAG.T22.56_00275 485918.Cpin_0688 8.2e-81 307.4 Sphingobacteriia lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IVKB@117747,4NFXA@976,COG1044@1,COG1044@2 NA|NA|NA M glucosamine N-acyltransferase MAG.T22.56_00276 485918.Cpin_0699 3.2e-34 151.8 Sphingobacteriia rimL GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 1.1.1.25 ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1IST4@117747,4NQ4Z@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_00277 485918.Cpin_0928 1.3e-194 686.0 Sphingobacteriia purH 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IP42@117747,4NEZD@976,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH MAG.T22.56_00278 1122605.KB893626_gene2815 9.7e-76 291.6 Sphingobacteriia comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1IQH4@117747,4NEJH@976,COG0658@1,COG0658@2 NA|NA|NA S TIGRFAM ComEC Rec2-related protein MAG.T22.56_00279 929556.Solca_3346 2.8e-95 356.3 Sphingobacteriia ko:K19804 ko00000 Bacteria 1J0XE@117747,4PKMW@976,COG1729@1,COG1729@2,COG2956@1,COG2956@2 NA|NA|NA G Tetratricopeptide repeat MAG.T22.56_00281 485918.Cpin_7062 0.0 1104.7 Sphingobacteriia fadB 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782,ko:K07516 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 iYO844.BSU32840 Bacteria 1IPN0@117747,4NF9D@976,COG1024@1,COG1024@2,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase MAG.T22.56_00283 926549.KI421517_gene4073 4.2e-49 201.1 Cytophagia Bacteria 47PW3@768503,4NNK3@976,COG3034@1,COG3034@2 NA|NA|NA M ErfK YbiS YcfS YnhG family protein MAG.T22.56_00284 485918.Cpin_0692 4.4e-146 524.2 Sphingobacteriia pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1IPG1@117747,4NF8I@976,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily MAG.T22.56_00285 485918.Cpin_0690 1.1e-85 323.6 Sphingobacteriia 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 1IQ5S@117747,4NFZH@976,COG0451@1,COG0451@2 NA|NA|NA M NAD dependent epimerase dehydratase family MAG.T22.56_00286 925409.KI911562_gene783 1.1e-199 703.0 Sphingobacteriia rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 1IPNZ@117747,4NEFP@976,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T22.56_00287 1121373.KB903620_gene2129 4.9e-109 402.5 Cytophagia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 47XXU@768503,4PKBQ@976,COG3209@1,COG3209@2,COG3386@1,COG3386@2,COG4547@1,COG4547@2 NA|NA|NA M SprB repeat MAG.T22.56_00288 700598.Niako_6250 2.4e-33 147.9 Sphingobacteriia 3.4.19.5 ko:K03088,ko:K13051 ko00000,ko01000,ko01002,ko03021 Bacteria 1ITI3@117747,4NS9D@976,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T22.56_00289 485918.Cpin_0522 1.3e-268 932.2 Sphingobacteriia coxN 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 1IPZE@117747,4NEH8@976,COG0843@1,COG0843@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T22.56_00290 485918.Cpin_0523 2.1e-111 409.1 Sphingobacteriia coxM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1IPEE@117747,4NFNF@976,COG1622@1,COG1622@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T22.56_00291 700598.Niako_6473 3.6e-115 421.8 Sphingobacteriia actF Bacteria 1IPBN@117747,4NF0R@976,COG4531@1,COG4531@2 NA|NA|NA P Quinol cytochrome c oxidoreductase MAG.T22.56_00292 485918.Cpin_0525 4.4e-38 164.9 Sphingobacteriia actE Bacteria 1IRVN@117747,4NKQI@976,COG2010@1,COG2010@2 NA|NA|NA C cytochrome C MAG.T22.56_00293 925409.KI911562_gene1018 1.2e-73 282.7 Sphingobacteriia actD Bacteria 1ITKW@117747,4NEX9@976,COG2010@1,COG2010@2 NA|NA|NA C Quinol cytochrome c oxidoreductase MAG.T22.56_00294 485918.Cpin_0527 4.5e-237 827.0 Sphingobacteriia actC ko:K00185 ko00000 5.A.3 Bacteria 1INKZ@117747,4NE3X@976,COG5557@1,COG5557@2 NA|NA|NA C PFAM Polysulphide reductase, NrfD MAG.T22.56_00295 485918.Cpin_0528 0.0 1181.8 Sphingobacteriia actB ko:K00184 ko00000 5.A.3 Bacteria 1IPWZ@117747,4NE5M@976,COG0243@1,COG0243@2,COG0437@1,COG0437@2 NA|NA|NA C Oxidoreductase MAG.T22.56_00296 485918.Cpin_0529 3.4e-135 488.4 Sphingobacteriia psbV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 ko:K02720 ko00195,ko01100,map00195,map01100 ko00000,ko00001,ko00194 iJN678.psbV Bacteria 1IPBV@117747,4NF0A@976,COG2010@1,COG2010@2 NA|NA|NA C PFAM Cytochrome c, class I MAG.T22.56_00297 391587.KAOT1_22051 8.2e-84 317.0 Flavobacteriia Bacteria 1HY8Z@117743,4NICN@976,COG1028@1,COG1028@2 NA|NA|NA IQ short-chain dehydrogenase MAG.T22.56_00298 925409.KI911562_gene1627 1.2e-88 332.8 Sphingobacteriia rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1IPC1@117747,4NFQM@976,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA MAG.T22.56_00299 485918.Cpin_6927 2.2e-22 111.3 Sphingobacteriia purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1ITNI@117747,4NV1M@976,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.56_00300 485918.Cpin_6928 2.3e-54 219.2 Sphingobacteriia pssA 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISNC@117747,4NNUZ@976,COG1183@1,COG1183@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T22.56_00301 485918.Cpin_1246 3.5e-102 377.9 Sphingobacteriia Bacteria 1IP15@117747,4NF1I@976,COG0745@1,COG0745@2 NA|NA|NA T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain MAG.T22.56_00302 485918.Cpin_6913 1.8e-09 68.9 Sphingobacteriia ko:K02014,ko:K16087 ko00000,ko02000 1.B.14,1.B.14.2 Bacteria 1J0PK@117747,4NG13@976,COG4772@1,COG4772@2 NA|NA|NA P Type IX secretion system membrane protein PorP/SprF MAG.T22.56_00303 1124780.ANNU01000035_gene272 4.6e-62 245.0 Cytophagia MA20_36650 Bacteria 47PHD@768503,4NGZ3@976,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.56_00304 700598.Niako_6091 6.7e-62 244.6 Sphingobacteriia Bacteria 1IX57@117747,4NFRJ@976,COG0707@1,COG0707@2 NA|NA|NA M Glycosyl transferase family 1 MAG.T22.56_00307 1123248.KB893337_gene2401 1.6e-43 183.0 Sphingobacteriia 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 1IPIK@117747,4NIDS@976,COG1633@1,COG1633@2 NA|NA|NA S Ferritin-like domain MAG.T22.56_00308 1123248.KB893337_gene2400 1.3e-39 170.2 Sphingobacteriia 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 1IQ3Q@117747,4NHJB@976,COG1633@1,COG1633@2 NA|NA|NA S Ferritin-like domain MAG.T22.56_00309 485918.Cpin_6575 1.2e-232 813.1 Sphingobacteriia priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1IQGH@117747,4NFHB@976,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA MAG.T22.56_00310 700598.Niako_6972 1.5e-156 559.3 Sphingobacteriia clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1IP06@117747,4NE1B@976,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP MAG.T22.56_00313 700598.Niako_4591 2.5e-41 175.3 Sphingobacteriia folA 1.1.1.262,1.5.1.3 ko:K00097,ko:K00287,ko:K18589 ko00670,ko00750,ko00790,ko01100,ko01523,map00670,map00750,map00790,map01100,map01523 M00124,M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R05681,R05837,R07406,R11765 RC00089,RC00109,RC00110,RC00158,RC00675,RC01475 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1ISG3@117747,4NQ2Y@976,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis MAG.T22.56_00314 925409.KI911562_gene1573 1e-126 459.5 Sphingobacteriia thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1IRAS@117747,4NEC2@976,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis MAG.T22.56_00315 926562.Oweho_1292 2.9e-104 384.8 Cryomorphaceae Bacteria 1HYRX@117743,2PAI9@246874,4NF0S@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.56_00316 485918.Cpin_0426 3.7e-69 267.7 Sphingobacteriia dapH Bacteria 1IS18@117747,4NG6R@976,COG0663@1,COG0663@2 NA|NA|NA S COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily MAG.T22.56_00317 402612.FP2019 2.5e-26 125.9 Flavobacterium ko:K07275 ko00000 Bacteria 1IJ6I@117743,2P0JR@237,4NY5Z@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.56_00318 1237149.C900_04408 0.0 1785.8 Cytophagia icmF GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 ko00000,ko01000 Bacteria 47KS7@768503,4NFHX@976,COG1703@1,COG1703@2,COG1884@1,COG1884@2,COG2185@1,COG2185@2 NA|NA|NA EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly MAG.T22.56_00319 760192.Halhy_0783 1.4e-144 519.6 Bacteria ko:K06889,ko:K09914 ko00000 Bacteria COG0265@1,COG0265@2,COG1073@1,COG1073@2 NA|NA|NA O serine-type endopeptidase activity MAG.T22.56_00320 755732.Fluta_2834 1.3e-182 646.7 Flavobacteriia Bacteria 1HZCD@117743,4NGBJ@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent receptor MAG.T22.56_00321 755732.Fluta_2835 2.9e-34 152.1 Flavobacteriia Bacteria 1I677@117743,2C9AB@1,2ZB91@2,4NKQ3@976 NA|NA|NA MAG.T22.56_00322 926562.Oweho_1087 2.3e-49 202.6 Cryomorphaceae Bacteria 1IFCY@117743,2DKFZ@1,2PB0S@246874,309D6@2,4PK7J@976 NA|NA|NA S Domain of unknown function (DUF4382) MAG.T22.56_00323 635013.TherJR_1409 2.7e-26 127.5 Peptococcaceae Bacteria 1V7EF@1239,24M0T@186801,265QD@186807,COG1287@1,COG1287@2 NA|NA|NA S oligosaccharyl transferase activity MAG.T22.56_00324 1121481.AUAS01000011_gene5112 1.6e-11 75.5 Bacteroidetes Bacteria 29A7B@1,2ZX8B@2,4P8BK@976 NA|NA|NA MAG.T22.56_00325 761193.Runsl_0828 4.3e-264 917.5 Cytophagia Bacteria 47Y3C@768503,4NE4M@976,COG1629@1,COG4771@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.56_00326 700598.Niako_6498 1e-161 576.6 Sphingobacteriia dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 iJN678.dgt Bacteria 1IQI8@117747,4NENM@976,COG0232@1,COG0232@2 NA|NA|NA F TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase MAG.T22.56_00327 880071.Fleli_3472 4.1e-96 357.8 Cytophagia Bacteria 47U0W@768503,4NGQY@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.56_00328 929562.Emtol_2566 1.7e-66 259.6 Bacteria 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria COG0596@1,COG0596@2 NA|NA|NA S hydrolase activity, acting on ester bonds MAG.T22.56_00329 1123248.KB893329_gene4480 7.3e-132 477.2 Sphingobacteriia queA 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1IWHH@117747,4NDZ5@976,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T22.56_00330 700598.Niako_6865 6e-101 374.0 Sphingobacteriia nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1988 Bacteria 1INNF@117747,4NDXF@976,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family MAG.T22.56_00331 1279009.ADICEAN_02922 9.3e-52 210.7 Cytophagia dagK Bacteria 47PDK@768503,4NJWB@976,COG1597@1,COG1597@2 NA|NA|NA I PFAM Diacylglycerol kinase, catalytic MAG.T22.56_00332 700598.Niako_6678 1.1e-57 230.3 Sphingobacteriia waaM 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1J0BY@117747,4NPAI@976,COG1560@1,COG1560@2 NA|NA|NA M Bacterial lipid A biosynthesis acyltransferase MAG.T22.56_00333 700598.Niako_2022 5.1e-87 327.4 Sphingobacteriia yadF 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273 Bacteria 1IPRZ@117747,4NEJT@976,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T22.56_00334 485918.Cpin_0499 6.3e-137 493.8 Sphingobacteriia fahA2 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 Bacteria 1IRA7@117747,4NGI0@976,COG0179@1,COG0179@2 NA|NA|NA Q PFAM fumarylacetoacetate (FAA) hydrolase MAG.T22.56_00337 1123248.KB893314_gene3481 2.4e-30 139.8 Sphingobacteriia Bacteria 1IT7E@117747,4NH7M@976,COG1566@1,COG1566@2 NA|NA|NA V Protein of unknown function (DUF3667) MAG.T22.56_00338 929703.KE386491_gene3827 3.9e-21 107.8 Cytophagia Bacteria 29WC5@1,30HXS@2,47SJP@768503,4NNWN@976 NA|NA|NA MAG.T22.56_00339 313606.M23134_05335 5.6e-100 372.5 Cytophagia Bacteria 47PGJ@768503,4NEZQ@976,COG1372@1,COG1372@2,COG4447@1,COG4447@2,COG5184@1,COG5184@2,COG5492@1,COG5492@2 NA|NA|NA G Participates in initiation and elongation during chromosome replication MAG.T22.56_00340 485918.Cpin_6623 2.9e-54 218.8 Sphingobacteriia ko:K02477 ko00000,ko02022 Bacteria 1IXDB@117747,4NPFH@976,COG3279@1,COG3279@2 NA|NA|NA T LytTr DNA-binding domain MAG.T22.56_00341 714943.Mucpa_5776 1.1e-97 365.5 Sphingobacteriia Bacteria 1IRJZ@117747,4NDXU@976,COG0642@1,COG0642@2,COG2205@2,COG3292@1,COG3292@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_00342 649349.Lbys_0959 5.2e-88 330.5 Cytophagia Bacteria 47P5R@768503,4NQWV@976,COG0664@1,COG0664@2 NA|NA|NA T PFAM Cyclic nucleotide-binding domain MAG.T22.56_00343 761193.Runsl_3832 1.3e-93 349.4 Cytophagia Bacteria 2CA4G@1,2Z7UW@2,47MGT@768503,4NFG9@976 NA|NA|NA MAG.T22.56_00344 1089547.KB913013_gene881 6.3e-79 300.4 Cytophagia Bacteria 2CA4G@1,2Z7UW@2,47KPW@768503,4NFG9@976 NA|NA|NA MAG.T22.56_00345 269798.CHU_1450 1.6e-47 195.7 Cytophagia Bacteria 313GU@2,47QTF@768503,4NQIM@976,arCOG06733@1 NA|NA|NA MAG.T22.56_00346 760192.Halhy_1848 1.8e-19 102.4 Bacteroidetes Bacteria 2EE0T@1,337VK@2,4NWU8@976 NA|NA|NA MAG.T22.56_00348 471854.Dfer_0990 4.3e-147 528.5 Cytophagia Bacteria 47Y64@768503,4P5EA@976,COG2202@1,COG2202@2,COG2203@1,COG2203@2 NA|NA|NA T Domain present in phytochromes and cGMP-specific phosphodiesterases. MAG.T22.56_00349 443143.GM18_2242 6.7e-82 311.6 Proteobacteria 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R4XH@1224,COG2730@1,COG2730@2 NA|NA|NA G Belongs to the glycosyl hydrolase 5 (cellulase A) family MAG.T22.56_00350 1121481.AUAS01000011_gene4973 1.3e-165 589.3 Cytophagia rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 47MFH@768503,4NFJM@976,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily MAG.T22.56_00352 1131812.JQMS01000001_gene2230 1.9e-47 195.7 Flavobacterium 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1I3AA@117743,2NVAR@237,4NNT2@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase MAG.T22.56_00353 1270196.JCKI01000005_gene2835 2.3e-31 141.0 Sphingobacteriia ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 Bacteria 1IYWT@117747,4NSK8@976,COG3369@1,COG3369@2 NA|NA|NA S Iron-binding zinc finger CDGSH type MAG.T22.56_00354 391587.KAOT1_03132 4e-17 95.5 Flavobacteriia Bacteria 1I5S9@117743,4NRSC@976,COG3076@1,COG3076@2 NA|NA|NA S TIGR01619 family MAG.T22.56_00356 1296415.JACC01000003_gene3109 3.3e-09 68.9 Aquimarina Bacteria 1I34P@117743,2YK50@290174,4NR9K@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.56_00357 485918.Cpin_3586 0.0 1078.2 Sphingobacteriia Bacteria 1IPRU@117747,4NETM@976,COG1032@1,COG1032@2 NA|NA|NA C Elongator protein 3, MiaB family, Radical SAM MAG.T22.56_00358 485918.Cpin_6821 8.2e-45 187.2 Sphingobacteriia Bacteria 1IRVH@117747,4NJW3@976,COG2197@1,COG2197@2 NA|NA|NA T Two component transcriptional regulator, LuxR family MAG.T22.56_00359 1296415.JACC01000001_gene3550 2.6e-34 152.5 Aquimarina Bacteria 1I1SW@117743,2YHIX@290174,4NNE1@976,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.56_00362 485918.Cpin_2321 6.3e-191 673.7 Sphingobacteriia pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iAF987.Gmet_0122 Bacteria 1IPRW@117747,4NEEU@976,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family MAG.T22.56_00363 1122176.KB903532_gene2638 3.5e-26 125.2 Sphingobacteriia Bacteria 1IZ79@117747,2CE7Q@1,32RZA@2,4NSYK@976 NA|NA|NA MAG.T22.56_00364 743719.PaelaDRAFT_0710 6.7e-17 94.0 Bacilli Bacteria 1V81G@1239,4HIZ9@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.56_00365 700598.Niako_1525 4.3e-70 271.6 Sphingobacteriia panC GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 ko:K01918,ko:K13799 ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110 M00052,M00119 R00158,R00512,R01665,R02473 RC00002,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ34@117747,4NFT9@976,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate MAG.T22.56_00366 468059.AUHA01000004_gene2291 2e-32 146.7 Sphingobacteriia Bacteria 1J0JA@117747,4PM6M@976,COG1572@1,COG1572@2 NA|NA|NA S Aerotolerance regulator N-terminal MAG.T22.56_00367 1123248.KB893334_gene2734 2.1e-110 406.0 Sphingobacteriia pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1IRB4@117747,4NDUZ@976,COG0044@1,COG0044@2 NA|NA|NA F Dihydroorotase, multifunctional complex type MAG.T22.56_00370 929713.NIASO_09020 3.3e-124 451.4 Sphingobacteriia arnC 2.4.1.83,2.4.2.53 ko:K00721,ko:K10012,ko:K20534 ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503 M00721,M00761 R01009,R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8,4.D.2.1.9 GT2 Bacteria 1J0R0@117747,4PKF3@976,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T22.56_00372 269798.CHU_2780 3.4e-43 183.3 Cytophagia Bacteria 47Y09@768503,4PM2F@976,COG3386@1,COG3386@2 NA|NA|NA G C-terminal domain of CHU protein family MAG.T22.56_00373 485918.Cpin_0784 4.4e-257 894.0 Sphingobacteriia feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 1IPAK@117747,4NEII@976,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system MAG.T22.56_00374 1121904.ARBP01000010_gene2447 2.4e-38 166.4 Cytophagia 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 47XY5@768503,4NMJA@976,COG4251@1,COG4251@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_00375 1500281.JQKZ01000024_gene2753 4.1e-42 179.1 Flavobacteriia ina Bacteria 1IKWB@117743,4NT37@976,COG3210@1,COG3210@2,COG4886@1,COG4886@2 NA|NA|NA U Chaperone of endosialidase MAG.T22.56_00376 1123248.KB893320_gene3930 6.5e-43 179.9 Sphingobacteriia iscA ko:K13628 ko00000,ko03016 Bacteria 1IT1Q@117747,4NQC8@976,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T22.56_00377 1356852.N008_15185 5e-64 250.4 Bacteroidetes iscU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055 Bacteria 4NM9Z@976,COG0822@1,COG0822@2 NA|NA|NA C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters MAG.T22.56_00378 925409.KI911562_gene1413 5.4e-199 700.3 Sphingobacteriia iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 iPC815.YPO2896,iYL1228.KPN_02862 Bacteria 1IQ14@117747,4NG58@976,COG1104@1,COG1104@2 NA|NA|NA E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins MAG.T22.56_00379 925409.KI911562_gene1412 9.7e-49 199.5 Sphingobacteriia 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISVM@117747,4NNGG@976,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.56_00381 391587.KAOT1_19557 5.2e-45 188.3 Flavobacteriia Bacteria 1I105@117743,4NPRU@976,COG1708@1,COG1708@2 NA|NA|NA S nucleotidyltransferase activity MAG.T22.56_00382 945713.IALB_2764 1.4e-37 163.3 Bacteria ermC 2.1.1.137 ko:K07755 ko00000,ko01000 Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase MAG.T22.56_00383 714943.Mucpa_3263 8.2e-63 247.3 Sphingobacteriia 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1ITVA@117747,4NICK@976,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family MAG.T22.56_00384 700598.Niako_4338 4.4e-165 587.8 Sphingobacteriia 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 Bacteria 1IQPV@117747,4NETM@976,COG1032@1,COG1032@2 NA|NA|NA C Elongator protein 3, MiaB family, Radical SAM MAG.T22.56_00385 700598.Niako_4334 1.5e-41 176.8 Bacteroidetes Bacteria 4PNNX@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.56_00386 279010.BL03854 1.7e-37 163.3 Bacillus gspA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 Bacteria 1V2FM@1239,1ZCME@1386,4HFSG@91061,COG1442@1,COG1442@2 NA|NA|NA M General stress MAG.T22.56_00387 1267211.KI669560_gene586 5.7e-99 367.9 Sphingobacteriia corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1INUK@117747,4NG3C@976,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions MAG.T22.56_00388 1313301.AUGC01000003_gene2144 3.6e-64 251.5 Bacteroidetes 5.2.1.8 ko:K03768 ko00000,ko01000,ko03110 Bacteria 4NGT6@976,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T22.56_00389 925409.KI911562_gene504 2.9e-89 335.1 Sphingobacteriia nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1IPPM@117747,4NE7K@976,COG0177@1,COG0177@2 NA|NA|NA L Protein of unknown function (DUF2400) MAG.T22.56_00390 925409.KI911562_gene1521 4.4e-148 531.2 Sphingobacteriia hom 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06610 Bacteria 1IPM4@117747,4NHRC@976,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase MAG.T22.56_00391 700598.Niako_0119 1.4e-159 569.3 Sphingobacteriia metC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 ko:K01739,ko:K01760,ko:K10764,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11995,iYO844.BSU11880,iYO844.BSU27250 Bacteria 1INVN@117747,4NF0Q@976,COG0626@1,COG0626@2 NA|NA|NA E PFAM Cys Met metabolism MAG.T22.56_00392 616991.JPOO01000003_gene2175 1.5e-87 329.3 Arenibacter lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 iE2348C_1286.E2348C_0457 Bacteria 1HWZZ@117743,23GYF@178469,4NEF1@976,COG2908@1,COG2908@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T22.56_00393 485918.Cpin_0656 1.1e-36 159.8 Sphingobacteriia sixA ko:K08296 ko00000,ko01000 Bacteria 1ITFC@117747,4NQFM@976,COG2062@1,COG2062@2 NA|NA|NA T Phosphoglycerate mutase family MAG.T22.56_00394 700598.Niako_6679 1.2e-125 456.8 Sphingobacteriia GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K06958,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03019 Bacteria 1IV8P@117747,4NIT0@976,COG1660@1,COG1660@2,COG3178@1,COG3178@2 NA|NA|NA S P-loop ATPase protein family MAG.T22.56_00395 1267211.KI669560_gene2753 1.1e-92 346.3 Sphingobacteriia clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1IPWN@117747,4NE20@976,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T22.56_00396 945713.IALB_3117 6.6e-26 123.6 Bacteria Bacteria 2DTJ6@1,33KM6@2 NA|NA|NA MAG.T22.56_00397 700598.Niako_1533 4.4e-95 354.8 Sphingobacteriia Bacteria 1IXEE@117747,4NFN6@976,COG2755@1,COG2755@2 NA|NA|NA E GSCFA family MAG.T22.56_00398 700598.Niako_0374 3.8e-24 117.9 Sphingobacteriia Bacteria 1IU3X@117747,4NUZA@976,COG1664@1,COG1664@2 NA|NA|NA M Integral membrane protein CcmA involved in cell shape determination MAG.T22.56_00399 485918.Cpin_6611 1.2e-136 493.8 Sphingobacteriia yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1IQAZ@117747,4NESJ@976,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins MAG.T22.56_00400 700598.Niako_1212 1.8e-87 328.9 Sphingobacteriia ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 1IPTY@117747,4NF7N@976,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner MAG.T22.56_00401 1121104.AQXH01000001_gene1751 2.6e-61 241.5 Sphingobacteriia 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1IXS6@117747,4NNPH@976,COG0110@1,COG0110@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase MAG.T22.56_00402 1121104.AQXH01000001_gene1752 1.7e-145 522.3 Sphingobacteriia bplA 1.1.1.335 ko:K13020 ko00520,map00520 R10140 RC00182 ko00000,ko00001,ko01000,ko01005 Bacteria 1IR57@117747,4NFY3@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha beta domain MAG.T22.56_00403 761193.Runsl_3966 2.2e-39 169.9 Cytophagia Bacteria 47JPN@768503,4NPI2@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_00404 1454004.AW11_02504 5.5e-69 267.7 Betaproteobacteria hisF2 ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1RA6Q@1224,2VMU2@28216,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit MAG.T22.56_00405 156889.Mmc1_3091 6e-128 464.2 Alphaproteobacteria tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1NKHX@1224,2TVKU@28211,COG0037@1,COG0037@2 NA|NA|NA D ATPase of the PP-loop superfamily implicated in cell cycle control MAG.T22.56_00406 156889.Mmc1_3090 7.5e-63 248.1 Alphaproteobacteria 2.4.1.11 ko:K16150 ko00500,ko01100,map00500,map01100 R00292 RC00005 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1MVKK@1224,2TUFG@28211,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 MAG.T22.56_00407 1347342.BN863_29230 2.4e-54 219.2 Flavobacteriia 2.4.1.293 ko:K17250 ko00000,ko01000,ko01003 GT2 Bacteria 1IKQF@117743,4PMPA@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.56_00408 156889.Mmc1_2444 1.5e-68 266.5 Alphaproteobacteria rfbN ko:K12992,ko:K20444 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1PE8Y@1224,2UIV3@28211,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.56_00409 1279009.ADICEAN_03694 2.4e-120 438.7 Cytophagia rfaD 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 47TKC@768503,4NKVH@976,COG0451@1,COG0451@2 NA|NA|NA GM NAD(P)H-binding MAG.T22.56_00410 156889.Mmc1_2447 2.2e-57 229.6 Bacteria Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 MAG.T22.56_00411 156889.Mmc1_3091 2.4e-113 415.6 Alphaproteobacteria tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1NKHX@1224,2TVKU@28211,COG0037@1,COG0037@2 NA|NA|NA D ATPase of the PP-loop superfamily implicated in cell cycle control MAG.T22.56_00412 290397.Adeh_3056 2.1e-70 272.7 delta/epsilon subdivisions 2.4.1.152,2.4.1.65 ko:K20151 ko00000,ko01000,ko01003 GT10 Bacteria 1NKGF@1224,28IN0@1,2Z8NG@2,43051@68525 NA|NA|NA H Glycosyltransferase family 10 (fucosyltransferase) C-term MAG.T22.56_00413 1396141.BATP01000003_gene5215 6.1e-29 134.4 Verrucomicrobiae 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 2IWG4@203494,46XS4@74201,COG2518@1,COG2518@2 NA|NA|NA O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins MAG.T22.56_00414 1167006.UWK_00815 1.5e-08 67.0 Bacteria Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family MAG.T22.56_00415 156889.Mmc1_3091 1.9e-97 362.8 Alphaproteobacteria tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1NKHX@1224,2TVKU@28211,COG0037@1,COG0037@2 NA|NA|NA D ATPase of the PP-loop superfamily implicated in cell cycle control MAG.T22.56_00416 1123057.P872_01490 2e-41 176.8 Cytophagia Bacteria 47S3W@768503,4NH7K@976,COG0438@1,COG0438@2 NA|NA|NA M Pfam Glycosyl transferases group 1 MAG.T22.56_00417 1120965.AUBV01000009_gene3055 4.7e-121 441.4 Cytophagia rfbB 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 47JN7@768503,4NEDM@976,COG1134@1,COG1134@2 NA|NA|NA GM ABC-type polysaccharide polyol phosphate transport system ATPase component MAG.T22.56_00418 1123248.KB893314_gene3367 1.1e-92 346.7 Sphingobacteriia ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 1IRBJ@117747,4NF36@976,COG1682@1,COG1682@2 NA|NA|NA GM COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component MAG.T22.56_00419 926549.KI421517_gene2194 1.2e-137 496.1 Cytophagia fcl 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 R05692 RC01014 ko00000,ko00001,ko01000 Bacteria 47KAF@768503,4NDV4@976,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction MAG.T22.56_00420 485918.Cpin_1090 6.9e-169 600.1 Sphingobacteriia gmd GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 R00888 RC00402 ko00000,ko00001,ko01000 Bacteria 1IQAV@117747,4NEB6@976,COG1089@1,COG1089@2 NA|NA|NA M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose MAG.T22.56_00421 1123248.KB893314_gene3368 1.1e-97 363.6 Sphingobacteriia pimB GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 ko:K13668 R11703,R11704 ko00000,ko01000,ko01003 GT4 Bacteria 1IV78@117747,4NMR6@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_00422 153721.MYP_1288 4.5e-146 525.0 Cytophagia asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 47JSF@768503,4NFQ3@976,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T22.56_00423 485918.Cpin_4764 6.6e-156 558.1 Sphingobacteriia wzc GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 ko:K16692 ko00000,ko01000,ko01001 Bacteria 1IPJ8@117747,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM PFAM lipopolysaccharide biosynthesis MAG.T22.56_00424 1048983.EL17_16205 2.7e-50 205.7 Cytophagia ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 47KQN@768503,4NNJT@976,COG1596@1,COG1596@2 NA|NA|NA M Soluble ligand binding domain MAG.T22.56_00426 485918.Cpin_5495 9.1e-44 183.0 Sphingobacteriia Bacteria 1IU9P@117747,2ASD9@1,31HSR@2,4NQ71@976 NA|NA|NA S SMART PUR-alpha beta gamma DNA RNA-binding MAG.T22.56_00427 929556.Solca_4157 2.1e-43 182.6 Sphingobacteriia mqnB GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.4.2.1,3.2.2.26,3.2.2.9 ko:K01243,ko:K03784,ko:K11783 ko00130,ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,ko01230,map00130,map00230,map00240,map00270,map00760,map01100,map01110,map01230 M00034,M00609 R00194,R01401,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R08587,R10244 RC00033,RC00063,RC00122,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1IT1C@117747,4NQVQ@976,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T22.56_00428 485918.Cpin_6957 1.3e-56 225.7 Sphingobacteriia 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1ISCG@117747,4NNY0@976,COG0720@1,COG0720@2 NA|NA|NA H 6-pyruvoyl tetrahydrobiopterin synthase MAG.T22.56_00429 485918.Cpin_6956 2.8e-84 318.2 Sphingobacteriia folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPBD@117747,4NFC2@976,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase MAG.T22.56_00431 485918.Cpin_6959 2.5e-83 315.5 Sphingobacteriia mqnD ko:K07083,ko:K11785 ko00130,ko01110,map00130,map01110 R08589 RC02330 ko00000,ko00001,ko01000 Bacteria 1INXU@117747,4NFAN@976,COG2107@1,COG2107@2 NA|NA|NA S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T22.56_00432 925409.KI911562_gene1609 4.2e-55 221.1 Sphingobacteriia hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 ko:K00760,ko:K00939,ko:K15780 ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130 M00049 R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319 RC00002,RC00063,RC00122 ko00000,ko00001,ko00002,ko01000,ko03016,ko04147 iHN637.CLJU_RS16720 Bacteria 1ISTD@117747,4NNIB@976,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family MAG.T22.56_00433 926549.KI421517_gene510 1.1e-13 85.1 Cytophagia ko:K08307 ko00000,ko01000,ko01011 Bacteria 47JZ1@768503,4NHG0@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM Transglycosylase SLT domain MAG.T22.56_00435 700598.Niako_5626 7.2e-42 176.8 Sphingobacteriia 5.4.99.13,5.4.99.2 ko:K01849,ko:K11942 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISIG@117747,4NNXP@976,COG2185@1,COG2185@2 NA|NA|NA I COGs COG2185 Methylmalonyl-CoA mutase C-terminal domain subunit (cobalamin-binding) MAG.T22.56_00436 1122605.KB893646_gene100 2e-90 339.0 Sphingobacteriia crt 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 R03026 RC00831 ko00000,ko00001,ko01000 Bacteria 1INKY@117747,4NFEM@976,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T22.56_00437 984262.SGRA_1104 1.8e-24 120.2 Sphingobacteriia Bacteria 1IXNX@117747,4PJ15@976,COG2067@1,COG2067@2 NA|NA|NA I Outer membrane protein beta-barrel domain MAG.T22.56_00438 700598.Niako_5087 8e-44 183.7 Sphingobacteriia ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1IQBR@117747,4NF4E@976,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB MAG.T22.56_00439 485918.Cpin_6946 0.0 2402.5 Sphingobacteriia greA Bacteria 1INS4@117747,4NEB8@976,COG1747@1,COG1747@2 NA|NA|NA S Motility related/secretion protein MAG.T22.56_00440 1267211.KI669560_gene742 3.8e-152 544.3 Sphingobacteriia paaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko01000 iEC55989_1330.EC55989_1524,iECO111_1330.ECO111_1782,iECO26_1355.ECO26_1992,iEcE24377_1341.EcE24377A_1573 Bacteria 1IVIY@117747,4NFJN@976,COG3396@1,COG3396@2 NA|NA|NA S Phenylacetic acid catabolic protein MAG.T22.56_00441 925409.KI911562_gene1071 1.2e-45 189.1 Sphingobacteriia paaB ko:K02610 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1IYP8@117747,4NQFV@976,COG3460@1,COG3460@2 NA|NA|NA Q Phenylacetic acid degradation B MAG.T22.56_00442 45351.EDO26068 5.3e-97 360.9 Metazoa Metazoa 2SNFW@2759,3AJRE@33154,3BZXB@33208,COG3396@1 NA|NA|NA S Phenylacetic acid catabolic protein MAG.T22.56_00443 679937.Bcop_0076 4.3e-21 107.8 Bacteroidaceae tonB ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 2FPKW@200643,4AKHT@815,4NMG7@976,COG0810@1,COG0810@2 NA|NA|NA U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.56_00444 925409.KI911562_gene1069 7.5e-51 206.8 Sphingobacteriia paaD GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 iECSE_1348.ECSE_1476 Bacteria 1IXUP@117747,4NMS0@976,COG2151@1,COG2151@2 NA|NA|NA L Pfam:DUF59 MAG.T22.56_00445 485918.Cpin_0361 1.9e-63 249.2 Sphingobacteriia rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1IPYG@117747,4NE0N@976,COG0571@1,COG0571@2 NA|NA|NA K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism MAG.T22.56_00446 1270196.JCKI01000007_gene2499 1.3e-176 625.9 Sphingobacteriia fabF 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iSB619.SA_RS04785 Bacteria 1IPBP@117747,4NEKC@976,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T22.56_00447 485918.Cpin_0363 3.1e-31 140.6 Sphingobacteriia acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1ITA3@117747,4NS6C@976,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T22.56_00448 1123248.KB893314_gene3586 1.9e-73 282.3 Sphingobacteriia lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 1IPBQ@117747,4NGDU@976,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of MAG.T22.56_00449 700598.Niako_5479 7e-33 146.0 Sphingobacteriia Bacteria 1ITH1@117747,2C8VT@1,32RN1@2,4NS78@976 NA|NA|NA S Protein of unknown function (DUF2795) MAG.T22.56_00450 700598.Niako_3021 1.4e-28 133.7 Sphingobacteriia Bacteria 1IWXM@117747,4NRDH@976,COG3291@1,COG3291@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_00451 1122176.KB903554_gene3877 4.7e-64 252.7 Bacteroidetes Bacteria 4PN79@976,COG3291@1,COG3291@2 NA|NA|NA G C-terminal domain of CHU protein family MAG.T22.56_00453 1458357.BG58_23775 2.4e-45 189.5 Burkholderiaceae yhhW_2 ko:K06911 ko00000 Bacteria 1K4AM@119060,1MWIP@1224,2VHGK@28216,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family MAG.T22.56_00454 1408433.JHXV01000020_gene3503 1.1e-36 159.8 Flavobacteriia 5.3.4.1 ko:K01829 ko00000,ko01000 Bacteria 1IJFT@117743,4PKUQ@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T22.56_00455 525373.HMPREF0766_14292 5e-26 124.4 Sphingobacteriia Bacteria 1ITTD@117747,2CN7E@1,32SGC@2,4NSFT@976 NA|NA|NA MAG.T22.56_00456 1233951.IO90_05110 5.6e-07 63.2 Flavobacteriia Bacteria 1HYN2@117743,4NRP7@976,COG4447@1,COG4447@2 NA|NA|NA S Photosynthesis system II assembly factor YCF48 MAG.T22.56_00457 485918.Cpin_1663 3.5e-300 1037.3 Sphingobacteriia purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1IR8F@117747,4NETY@976,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.56_00458 925409.KI911562_gene909 4.1e-56 224.2 Sphingobacteriia tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K04075,ko:K11991 ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko01002,ko01011,ko03016 Bacteria 1ISDN@117747,4NNJ2@976,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) MAG.T22.56_00459 925409.KI911562_gene631 5.7e-20 103.6 Sphingobacteriia MA20_19305 ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 Bacteria 1ITVU@117747,4NV9E@976,COG2146@1,COG2146@2 NA|NA|NA P Rieske (2Fe-2S) domain MAG.T22.56_00460 1158294.JOMI01000009_gene892 1.1e-44 187.6 Bacteroidetes Bacteria 28MAE@1,2ZAP3@2,4NF86@976 NA|NA|NA S YARHG MAG.T22.56_00461 1123248.KB893324_gene1747 6.6e-93 347.4 Sphingobacteriia ykfA 3.4.17.13 ko:K01297 ko00000,ko01000,ko01002,ko01011 Bacteria 1IPHC@117747,4NF5Q@976,COG1619@1,COG1619@2 NA|NA|NA V peptidase MAG.T22.56_00462 1123248.KB893324_gene1745 1.6e-16 92.0 Sphingobacteriia Bacteria 1J038@117747,4P7K2@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.56_00463 700598.Niako_6198 2.5e-154 551.6 Sphingobacteriia obg GO:0000003,GO:0000160,GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007059,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0019954,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0034622,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042254,GO:0042255,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1IP1F@117747,4NEK4@976,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control MAG.T22.56_00464 485918.Cpin_0838 5.2e-67 260.8 Sphingobacteriia adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IRJW@117747,4NG7J@976,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism MAG.T22.56_00465 1166018.FAES_3732 7.5e-60 236.9 Cytophagia rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 ko:K06178,ko:K06181 ko00000,ko01000,ko03009 Bacteria 47PFZ@768503,4NM4U@976,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T22.56_00466 509635.N824_03560 2.4e-21 109.4 Sphingobacteriia Bacteria 1ISXE@117747,4NH2K@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat MAG.T22.56_00467 485918.Cpin_0906 1.4e-91 343.2 Sphingobacteriia batB ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1IR1C@117747,4NF7Y@976,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A MAG.T22.56_00468 929713.NIASO_00620 4.4e-68 264.6 Sphingobacteriia Bacteria 1IRYA@117747,4NFC1@976,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) MAG.T22.56_00469 485918.Cpin_1021 4.1e-309 1067.0 Sphingobacteriia pcrA 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1IP3C@117747,4NDWN@976,COG0210@1,COG0210@2 NA|NA|NA L DNA helicase MAG.T22.56_00470 1111728.ATYS01000018_gene3361 1.2e-116 427.2 Gammaproteobacteria Bacteria 1N0IJ@1224,1S05Z@1236,COG5316@1,COG5316@2 NA|NA|NA S N-terminal domain of unknown function (DUF4140) MAG.T22.56_00471 929713.NIASO_19360 7.8e-15 86.7 Sphingobacteriia Bacteria 1IUJQ@117747,2E4AG@1,33IJ2@2,4P9RI@976 NA|NA|NA S Domain of unknown function (DUF4783) MAG.T22.56_00473 485918.Cpin_0475 6.9e-212 743.4 Sphingobacteriia gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 1INQA@117747,4NEQT@976,COG0696@1,COG0696@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate MAG.T22.56_00474 485918.Cpin_0460 9.8e-266 922.9 Sphingobacteriia ko:K07003 ko00000 Bacteria 1IQCU@117747,4NE0M@976,COG1033@1,COG1033@2 NA|NA|NA S of the RND superfamily MAG.T22.56_00476 700598.Niako_6323 3.3e-85 321.6 Sphingobacteriia yafV 3.5.1.3 ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 1INZJ@117747,4NE37@976,COG0388@1,COG0388@2 NA|NA|NA S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase MAG.T22.56_00478 925409.KI911562_gene2867 4.3e-111 408.7 Sphingobacteriia Bacteria 1IR4R@117747,4NE7V@976,COG1807@1,COG1807@2 NA|NA|NA M glycosyl transferase family 39 MAG.T22.56_00479 700598.Niako_2561 1.3e-116 426.4 Sphingobacteriia ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 R10938 RC03309 ko00000,ko01000 Bacteria 1IQ9P@117747,4NG8N@976,COG4948@1,COG4948@2 NA|NA|NA M Mandelate racemase muconate lactonizing enzyme MAG.T22.56_00480 485918.Cpin_6574 3.7e-105 388.3 Sphingobacteriia murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1IQP9@117747,4NE78@976,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation MAG.T22.56_00481 485918.Cpin_6300 5.6e-175 622.1 Sphingobacteriia zraS_1 Bacteria 1INZH@117747,4NE49@976,COG5000@1,COG5000@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.56_00482 485918.Cpin_6301 2.9e-94 351.7 Sphingobacteriia mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 ko:K02428,ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 iJN678.sll1005 Bacteria 1IR2F@117747,4NEA3@976,COG1694@1,COG3956@2 NA|NA|NA S PFAM MazG nucleotide pyrophosphohydrolase MAG.T22.56_00483 468059.AUHA01000003_gene1560 1.3e-57 229.2 Sphingobacteriia ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1INXX@117747,4NIBD@976,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN MAG.T22.56_00485 1313421.JHBV01000049_gene57 1.6e-40 174.9 Bacteria Bacteria COG2133@1,COG2133@2,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA G pyrroloquinoline quinone binding MAG.T22.56_00487 1346330.M472_11550 5.7e-156 557.4 Sphingobacteriia 4.1.1.11,4.1.1.25 ko:K18933 ko00350,ko00410,ko00680,ko00770,ko01100,ko01110,map00350,map00410,map00680,map00770,map01100,map01110 R00489,R00736 RC00299 ko00000,ko00001,ko01000 Bacteria 1IQ1M@117747,4NGRW@976,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain MAG.T22.56_00488 700598.Niako_6521 5.6e-192 677.2 Sphingobacteriia blh Bacteria 1IP4Z@117747,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P PFAM Metallo-beta-lactamase superfamily MAG.T22.56_00489 485918.Cpin_0678 8.6e-72 276.9 Sphingobacteriia ko:K01420,ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1IQHB@117747,4NFB1@976,COG0664@1,COG0664@2 NA|NA|NA K - catabolite gene activator and regulatory subunit of cAMP-dependent protein MAG.T22.56_00491 929556.Solca_1389 4.5e-237 827.8 Sphingobacteriia fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1IPQU@117747,4NEI1@976,COG2217@1,COG2217@2,COG2608@1,COG2608@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T22.56_00493 1123248.KB893386_gene1898 0.0 1196.0 Sphingobacteriia ccoO GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404,ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144,iIT341.HP0145 Bacteria 1IP6D@117747,4NEGM@976,COG2993@1,COG2993@2,COG3278@1,COG3278@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T22.56_00494 485918.Cpin_0682 1.1e-07 62.0 Sphingobacteriia Bacteria 1IZP1@117747,4PJ6S@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_00495 700598.Niako_1943 1e-69 270.8 Sphingobacteriia ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1IRZW@117747,4NFMJ@976,COG2010@1,COG2010@2 NA|NA|NA C PFAM Cytochrome c, class I MAG.T22.56_00496 929556.Solca_1394 3.3e-168 598.2 Sphingobacteriia ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1IP29@117747,4NFDN@976,COG0348@1,COG0348@2 NA|NA|NA C cytochrome c oxidase MAG.T22.56_00497 485918.Cpin_0685 3.3e-21 108.2 Sphingobacteriia ccoH ko:K09926 ko00000 Bacteria 1IU6K@117747,4PPZ3@976,COG3198@1,COG3198@2 NA|NA|NA S FixH family MAG.T22.56_00498 946077.W5A_08382 6.4e-35 154.5 Flavobacteriia braZ ko:K09792 ko00000 Bacteria 1HXIX@117743,4NF84@976,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome c biogenesis protein MAG.T22.56_00499 1034347.CAHJ01000066_gene2912 5.9e-11 73.9 Bacillus Bacteria 1U00Q@1239,1ZK9S@1386,2CH44@1,30Q8S@2,4IC9V@91061 NA|NA|NA MAG.T22.56_00500 760192.Halhy_3406 3.6e-55 221.9 Sphingobacteriia 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1IS2C@117747,4NMUT@976,COG4464@1,COG4464@2 NA|NA|NA GM COG4464 Capsular polysaccharide biosynthesis protein MAG.T22.56_00501 926562.Oweho_1399 2.9e-131 474.9 Bacteroidetes Bacteria 4NI4N@976,COG0451@1,COG0451@2 NA|NA|NA GM NAD-dependent epimerase MAG.T22.56_00502 266748.HY04_10090 3.8e-138 498.0 Chryseobacterium 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1HX99@117743,3ZT4N@59732,4NFAI@976,COG0399@1,COG0399@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T22.56_00503 1121912.AUHD01000001_gene2258 3.9e-105 388.3 Flavobacteriia Bacteria 1IIX7@117743,4NFDB@976,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase MAG.T22.56_00504 760192.Halhy_3411 4.8e-51 207.6 Sphingobacteriia Bacteria 1IT8B@117747,4NS23@976,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator MAG.T22.56_00505 1123234.AUKI01000015_gene2264 4.3e-30 137.9 Flavobacteriia nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601,ko:K05785 ko00000,ko03000,ko03009,ko03021 Bacteria 1I39D@117743,4NSVU@976,COG0250@1,COG0250@2 NA|NA|NA K PFAM Transcription termination factor nusG MAG.T22.56_00506 367737.Abu_0666 8.2e-158 563.1 Epsilonproteobacteria 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVI8@1224,2YNUV@29547,43AN9@68525,COG0451@1,COG0451@2 NA|NA|NA M NmrA-like family MAG.T22.56_00507 313606.M23134_05639 1.3e-157 562.8 Cytophagia Bacteria 47QH2@768503,4NFQ8@976,COG0399@1,COG0399@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T22.56_00508 1296416.JACB01000017_gene5229 2.8e-279 967.6 Aquimarina asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1HXV0@117743,2YGW5@290174,4NFQ3@976,COG0367@1,COG0367@2 NA|NA|NA E Glutamine amidotransferase domain MAG.T22.56_00509 1304888.ATWF01000002_gene377 2.5e-47 195.3 Bacteria 2.3.1.209,2.3.1.79 ko:K00661,ko:K21379 ko00000,ko01000 Bacteria COG0110@1,COG0110@2 NA|NA|NA S O-acyltransferase activity MAG.T22.56_00510 1538644.KO02_12755 5.2e-29 134.0 Sphingobacteriia oxyR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141 ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1INST@117747,4NGZ5@976,COG0583@1,COG0583@2 NA|NA|NA K transcriptional regulator MAG.T22.56_00511 760192.Halhy_2419 4.1e-20 105.1 Bacteroidetes speE 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 4NPK5@976,COG0421@1,COG0421@2 NA|NA|NA E Spermidine synthase MAG.T22.56_00512 385682.AFSL01000064_gene1700 1.3e-76 293.1 Marinilabiliaceae Bacteria 2FQJ1@200643,3XJXP@558415,4NE0J@976,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T22.56_00513 485918.Cpin_6513 1.1e-70 273.1 Sphingobacteriia plsY 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IPFE@117747,4NMU3@976,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP MAG.T22.56_00514 1123248.KB893316_gene4531 5.6e-59 234.6 Sphingobacteriia prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1IQ5D@117747,4NFRW@976,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase MAG.T22.56_00515 485918.Cpin_0547 2.5e-74 287.0 Sphingobacteriia Bacteria 1IPTT@117747,4NE6G@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2 NA|NA|NA M OmpA MotB domain protein MAG.T22.56_00516 1123248.KB893315_gene3013 2.6e-45 189.5 Sphingobacteriia ko:K02014,ko:K16087 ko00000,ko02000 1.B.14,1.B.14.2 Bacteria 1J0PK@117747,4NG13@976,COG4772@1,COG4772@2 NA|NA|NA P Type IX secretion system membrane protein PorP/SprF MAG.T22.56_00518 1123248.KB893316_gene4651 2e-232 812.4 Sphingobacteriia ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1INVI@117747,4NE86@976,COG1674@1,COG1674@2 NA|NA|NA D DNA segregation ATPase FtsK SpoIIIE and related MAG.T22.56_00519 485918.Cpin_6264 7.1e-51 207.2 Sphingobacteriia ydcC Bacteria 1ISAH@117747,4NFGN@976,COG2834@1,COG2834@2 NA|NA|NA M PFAM Outer membrane lipoprotein carrier protein LolA MAG.T22.56_00521 1237149.C900_00952 1.2e-118 433.0 Cytophagia fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47JDE@768503,4NE1D@976,COG0331@1,COG0331@2 NA|NA|NA I malonyl CoA-acyl carrier protein transacylase MAG.T22.56_00522 485918.Cpin_2343 1.9e-34 151.8 Sphingobacteriia ytxJ Bacteria 1ITHB@117747,4NSE6@976,COG3118@1,COG3118@2 NA|NA|NA O Protein of unknown function (DUF2847) MAG.T22.56_00523 485918.Cpin_6233 1.4e-115 423.3 Sphingobacteriia norM_1 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 1IXI6@117747,4NFIR@976,COG0534@1,COG0534@2 NA|NA|NA V MatE MAG.T22.56_00525 700598.Niako_0915 4.7e-54 217.6 Sphingobacteriia rsmD 2.1.1.171 ko:K08316,ko:K15257 R07234 RC00003 ko00000,ko01000,ko03009,ko03016 Bacteria 1ISB1@117747,4NM7J@976,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD MAG.T22.56_00526 485918.Cpin_6230 1.1e-51 209.5 Sphingobacteriia coaD 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISUA@117747,4NM84@976,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate MAG.T22.56_00528 755732.Fluta_2705 1.7e-59 236.9 Cryomorphaceae Bacteria 1HZC4@117743,28PK5@1,2PB4K@246874,2ZC9N@2,4NI1X@976 NA|NA|NA MAG.T22.56_00529 929562.Emtol_0347 7.7e-32 144.1 Cytophagia 2.7.7.53,3.6.1.13,3.6.1.55 ko:K01515,ko:K03574,ko:K19710 ko00230,map00230 R00126,R01054,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000,ko03400 Bacteria 47Y1R@768503,4PKI3@976,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T22.56_00530 485918.Cpin_6227 7e-70 270.4 Sphingobacteriia pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1IPI8@117747,4NEF8@976,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) MAG.T22.56_00531 485918.Cpin_1958 1.4e-50 206.8 Sphingobacteriia ubiA 2.5.1.39,2.5.1.42 ko:K03179,ko:K17105 ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110 M00117 R04520,R05000,R05615 RC00209,RC01171,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1IYC2@117747,4NFRM@976,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T22.56_00532 1123248.KB893359_gene2143 5.3e-53 214.2 Sphingobacteriia maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0022402,GO:0022607,GO:0030145,GO:0030312,GO:0030428,GO:0032506,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044085,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1ISD6@117747,4NNXV@976,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T22.56_00533 485918.Cpin_1926 2.5e-110 405.6 Sphingobacteriia puuB ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPIG@117747,4NEEY@976,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase MAG.T22.56_00536 485918.Cpin_1254 0.0 1332.0 Sphingobacteriia leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1IP89@117747,4NE5K@976,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.56_00537 485918.Cpin_0532 1.9e-43 182.6 Sphingobacteriia ypmQ ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 1IY4A@117747,4NFH2@976,COG1999@1,COG1999@2 NA|NA|NA S SCO1/SenC MAG.T22.56_00538 485918.Cpin_0970 6.4e-161 573.9 Sphingobacteriia dbpA GO:0000027,GO:0000166,GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008135,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016043,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065003,GO:0065007,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 ko:K05591,ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1IQWW@117747,4NE4Z@976,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase domain protein MAG.T22.56_00539 1166018.FAES_1400 9.1e-52 209.9 Cytophagia Bacteria 47PZE@768503,4NNRD@976,COG2318@1,COG2318@2 NA|NA|NA S DinB family MAG.T22.56_00540 929556.Solca_3660 3.4e-84 318.5 Sphingobacteriia Bacteria 1IPSW@117747,4NHIC@976,COG2378@1,COG2378@2 NA|NA|NA K PFAM HTH domain MAG.T22.56_00541 761193.Runsl_0544 1.3e-20 106.3 Cytophagia Bacteria 47R2M@768503,4NW58@976,COG4978@1,COG4978@2 NA|NA|NA KT Transcriptional regulator MAG.T22.56_00542 746697.Aeqsu_1012 2.4e-27 129.8 Bacteroidetes Bacteria 2DQEX@1,336EW@2,4PP00@976 NA|NA|NA MAG.T22.56_00543 925409.KI911562_gene839 3.1e-146 525.0 Sphingobacteriia deaD Bacteria 1IR44@117747,4NEVI@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.56_00545 468059.AUHA01000006_gene2865 9.4e-154 550.1 Sphingobacteriia rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1INY6@117747,4NEVI@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.56_00546 1122621.ATZA01000052_gene17 2.6e-98 365.5 Sphingobacteriia ltaE 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 1IRJY@117747,4NEIH@976,COG2008@1,COG2008@2 NA|NA|NA E Beta-eliminating lyase MAG.T22.56_00547 1229276.DI53_2650 1.2e-20 106.7 Sphingobacteriia comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1J0B9@117747,4NJ4A@976,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif MAG.T22.56_00548 700598.Niako_6969 9.5e-166 589.7 Sphingobacteriia yngJ GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 ko:K00248,ko:K11410,ko:K18244 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 Bacteria 1IP19@117747,4NEHA@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.56_00550 925409.KI911562_gene1444 3.3e-123 448.0 Sphingobacteriia tklA 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPAD@117747,4NDWK@976,COG3959@1,COG3959@2 NA|NA|NA G Transketolase MAG.T22.56_00551 485918.Cpin_0937 3.8e-103 381.7 Sphingobacteriia mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1IPZD@117747,4NDZY@976,COG1194@1,COG1194@2 NA|NA|NA L TIGRFAM A G-specific adenine glycosylase MAG.T22.56_00552 485918.Cpin_0936 6.5e-54 216.9 Sphingobacteriia ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1ISJD@117747,4NQBK@976,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein MAG.T22.56_00553 925409.KI911562_gene1104 5e-121 441.4 Sphingobacteriia CP_0360 Bacteria 1IVGY@117747,4NDZ7@976,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain MAG.T22.56_00554 485918.Cpin_1954 5.9e-83 314.3 Sphingobacteriia Bacteria 1IP0V@117747,4NF8R@976,COG2912@1,COG2912@2 NA|NA|NA S Transglutaminase-like superfamily MAG.T22.56_00555 485918.Cpin_1955 0.0 1158.7 Sphingobacteriia topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1IPJD@117747,4NF9S@976,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone MAG.T22.56_00556 983544.Lacal_1846 4.9e-07 62.8 Flavobacteriia 4.2.2.3 ko:K01729 ko00051,map00051 R03706 ko00000,ko00001,ko01000 Bacteria 1HX50@117743,4NIM6@976,COG3291@1,COG3291@2,COG4412@1,COG4412@2,COG4886@1,COG4886@2 NA|NA|NA M M6 family metalloprotease domain protein MAG.T22.56_00557 485918.Cpin_6455 9.2e-132 476.9 Sphingobacteriia putA ko:K00318,ko:K18318 ko00330,ko00332,ko01100,ko01110,ko01130,ko02024,map00330,map00332,map01100,map01110,map01130,map02024 R10507 RC00083 ko00000,ko00001,ko01000 Bacteria 1IQ4H@117747,4NEH5@976,COG0506@1,COG0506@2 NA|NA|NA E Proline dehydrogenase MAG.T22.56_00558 1267211.KI669560_gene2860 2e-16 91.7 Sphingobacteriia divIC ko:K05589,ko:K12065,ko:K13052 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria 1IU2I@117747,4NURQ@976,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator MAG.T22.56_00559 929713.NIASO_11525 1.4e-181 642.5 Sphingobacteriia eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1IP9V@117747,4NF5M@976,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis MAG.T22.56_00560 485918.Cpin_6834 1.4e-158 565.8 Sphingobacteriia mnmA 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1IR3X@117747,4NFXZ@976,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 MAG.T22.56_00561 1123248.KB893317_gene4329 3.7e-84 318.5 Sphingobacteriia aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ2Q@117747,4NGSS@976,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) MAG.T22.56_00563 925409.KI911562_gene2586 2.2e-38 165.6 Sphingobacteriia ko:K03088,ko:K03091 ko00000,ko03021 Bacteria 1IRWR@117747,4NNEM@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_00565 485918.Cpin_6842 4.8e-177 627.9 Sphingobacteriia Bacteria 1IQ41@117747,4NF5T@976,COG2866@1,COG2866@2 NA|NA|NA E Peptidase M14, carboxypeptidase A MAG.T22.56_00566 743722.Sph21_2825 5.1e-26 123.2 Sphingobacteriia phhB 4.2.1.96 ko:K01724 ko00790,map00790 R04734 RC01208 ko00000,ko00001,ko01000,ko04147 Bacteria 1ITUM@117747,4NS9U@976,COG2154@1,COG2154@2 NA|NA|NA H PFAM Pterin 4 alpha carbinolamine dehydratase MAG.T22.56_00567 700598.Niako_0335 5.2e-39 167.2 Sphingobacteriia CP_0991 ko:K07117 ko00000 Bacteria 1IYW5@117747,4P66M@976,COG2940@1,COG2940@2 NA|NA|NA S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain MAG.T22.56_00568 1123248.KB893315_gene3195 4e-21 108.2 Sphingobacteriia Bacteria 1ITQ8@117747,2CBKC@1,32RTJ@2,4NTE7@976 NA|NA|NA MAG.T22.56_00569 485918.Cpin_7284 0.0 1530.0 Sphingobacteriia secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1IPHM@117747,4NF7C@976,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane MAG.T22.56_00571 485918.Cpin_6903 7e-180 636.7 Sphingobacteriia rlmI 2.1.1.191,2.1.1.72 ko:K00571,ko:K06969 ko00000,ko01000,ko02048,ko03009 Bacteria 1INTU@117747,4NG9S@976,COG1092@1,COG1092@2 NA|NA|NA J PUA domain containing protein MAG.T22.56_00572 485918.Cpin_6893 1.8e-136 493.0 Sphingobacteriia recN ko:K03631,ko:K07459 ko00000,ko03400 Bacteria 1IQ2B@117747,4NE3I@976,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA MAG.T22.56_00573 313606.M23134_07726 3e-143 516.2 Cytophagia glgE 2.4.1.18,2.4.99.16 ko:K00700,ko:K07214,ko:K16147 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110,R09994 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 47PGJ@768503,4NEZQ@976,COG0296@1,COG0296@2,COG1372@1,COG1372@2,COG1404@1,COG1404@2,COG4447@1,COG4447@2 NA|NA|NA G Participates in initiation and elongation during chromosome replication MAG.T22.56_00575 1227739.Hsw_2474 6e-169 601.3 Cytophagia tcdA2 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 47YHC@768503,4PMJC@976,COG0497@1,COG0497@2 NA|NA|NA L Peptidase S46 MAG.T22.56_00576 485918.Cpin_4711 3.3e-68 266.5 Sphingobacteriia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1ISKM@117747,4NNVK@976,COG3291@1,COG3291@2 NA|NA|NA S C-terminal domain of CHU protein family MAG.T22.56_00577 1123248.KB893329_gene4479 5e-99 368.2 Sphingobacteriia rprX 2.7.13.3 ko:K02484,ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1J0U6@117747,4PKBV@976,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_00578 700598.Niako_6915 3.5e-81 308.5 Sphingobacteriia ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1J1AC@117747,4NPDD@976,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system MAG.T22.56_00579 700598.Niako_6916 1.3e-74 286.6 Bacteroidetes ko:K01992,ko:K19341 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 4NICG@976,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein MAG.T22.56_00580 1267211.KI669560_gene2804 2.5e-47 195.7 Bacteroidetes Bacteria 29C3H@1,32VP8@2,4NXVV@976 NA|NA|NA MAG.T22.56_00582 485918.Cpin_3742 3.4e-304 1050.4 Sphingobacteriia thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1IPWX@117747,4NEFT@976,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) MAG.T22.56_00583 1123248.KB893337_gene2354 7.8e-65 253.4 Sphingobacteriia infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1IRGC@117747,4NIZ5@976,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins MAG.T22.56_00584 929556.Solca_3166 8e-110 403.7 Sphingobacteriia Bacteria 1IQH3@117747,4NEBI@976,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.56_00585 156889.Mmc1_3089 1.4e-30 140.6 Proteobacteria Bacteria 1P0NT@1224,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_00586 760192.Halhy_2879 8.5e-51 208.0 Sphingobacteriia Bacteria 1IU1Q@117747,4NT2P@976,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_00587 710111.FraQA3DRAFT_3012 3.6e-32 145.2 Bacteria crtF Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase MAG.T22.56_00588 1123248.KB893314_gene3344 1.5e-156 559.3 Sphingobacteriia orfL Bacteria 1ITGW@117747,4PGC8@976,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_00589 1347342.BN863_29160 1.9e-103 382.9 Flavobacteriia Bacteria 1I6ET@117743,4NJ1W@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_00590 1347342.BN863_29150 4.4e-44 185.3 Bacteria ko:K12988 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 MAG.T22.56_00591 1123248.KB893314_gene3341 1e-39 171.4 Sphingobacteriia Bacteria 1IXUN@117747,2E1YZ@1,32X7I@2,4NTC5@976 NA|NA|NA MAG.T22.56_00592 886379.AEWI01000052_gene2661 7.5e-67 261.2 Marinilabiliaceae Bacteria 2FTK8@200643,3XK9W@558415,4NMHA@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_00593 700598.Niako_6781 5.2e-256 890.2 Sphingobacteriia ko:K00612 ko00000,ko01000 Bacteria 1IWJ0@117747,4NEV9@976,COG2192@1,COG2192@2 NA|NA|NA H COGs COG2192 carbamoyl transferase NodU family MAG.T22.56_00594 1122176.KB903558_gene4199 1e-42 181.0 Sphingobacteriia wbjE Bacteria 1IR3N@117747,4NGU7@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 MAG.T22.56_00595 992406.RIA_1504 1.4e-75 289.3 Flavobacteriia pglC GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.36 ko:K03606,ko:K15915,ko:K19428 ko05111,map05111 R10184 RC00002 ko00000,ko00001,ko01000 Bacteria 1HWQ3@117743,4NF29@976,COG2148@1,COG2148@2 NA|NA|NA M Transferase MAG.T22.56_00596 391598.FBBAL38_02570 7.6e-21 107.5 Flavobacteriia ko:K19429 ko00000,ko01000 Bacteria 1I232@117743,4NNTF@976,COG0110@1,COG0110@2 NA|NA|NA S Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family MAG.T22.56_00597 1124780.ANNU01000038_gene178 3.5e-144 518.1 Cytophagia pglE 2.6.1.102,2.6.1.34 ko:K13010,ko:K15910,ko:K19430 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 47JTR@768503,4NFAI@976,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.56_00598 700598.Niako_6937 4.9e-20 103.6 Sphingobacteriia fjo13 Bacteria 1IUJM@117747,2E6VD@1,331EZ@2,4NUSW@976 NA|NA|NA S Protein of unknown function (DUF3098) MAG.T22.56_00599 485918.Cpin_1255 3.2e-73 282.0 Sphingobacteriia ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1INNN@117747,4NH05@976,COG2177@1,COG2177@2 NA|NA|NA D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily MAG.T22.56_00600 485918.Cpin_0708 2.6e-107 395.6 Sphingobacteriia 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQD9@117747,4NE5W@976,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T22.56_00601 700598.Niako_6111 2.4e-172 611.7 Sphingobacteriia hflX ko:K03665 ko00000,ko03009 Bacteria 1IR5V@117747,4NF0P@976,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis MAG.T22.56_00603 485918.Cpin_0539 2.5e-62 245.4 Sphingobacteriia Bacteria 1ISUQ@117747,4NNS3@976,COG5587@1,COG5587@2 NA|NA|NA S TIGRFAM TIGR02453 family protein MAG.T22.56_00604 925409.KI911562_gene2590 3.4e-142 511.5 Sphingobacteriia dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 1IPQJ@117747,4NG0S@976,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) MAG.T22.56_00605 485918.Cpin_2050 4.7e-119 434.9 Sphingobacteriia rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1INRC@117747,4NEAR@976,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease MAG.T22.56_00606 485918.Cpin_0182 5.3e-123 447.6 Sphingobacteriia galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1INXE@117747,4NEM9@976,COG1087@1,COG1087@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.56_00607 1123248.KB893385_gene4879 5.7e-189 667.5 Sphingobacteriia msbA ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 1IQ58@117747,4NE2D@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T22.56_00608 929713.NIASO_14955 5.7e-90 337.4 Sphingobacteriia cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c Bacteria 1INZ2@117747,4NE3Y@976,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.56_00609 925409.KI911562_gene368 3.6e-31 140.6 Sphingobacteriia 3.2.2.21 ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1IU7D@117747,4NMMI@976,COG0122@1,COG0122@2 NA|NA|NA L PFAM HhH-GPD superfamily base excision DNA repair protein MAG.T22.56_00611 755732.Fluta_2429 2.9e-26 125.9 Bacteria Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T22.56_00612 929556.Solca_0332 2.8e-222 778.5 Sphingobacteriia nhaA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 ko:K03281,ko:K03455,ko:K03499,ko:K05571,ko:K05844,ko:K07402,ko:K11105 ko00000,ko01000,ko02000,ko03009 2.A.36.6,2.A.37,2.A.38.1,2.A.38.4,2.A.49,2.A.63.1,2.A.63.2 Bacteria 1IQ4D@117747,4NGF6@976,COG0475@1,COG0475@2,COG0490@1,COG0490@2,COG0569@1,COG0569@2 NA|NA|NA P PFAM sodium hydrogen exchanger MAG.T22.56_00613 1346330.M472_07480 9.5e-236 822.8 Sphingobacteriia pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS09060,iYO844.BSU30560 Bacteria 1INP6@117747,4NEGI@976,COG1866@1,COG1866@2 NA|NA|NA C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA MAG.T22.56_00614 1123248.KB893324_gene1752 3.6e-101 375.2 Sphingobacteriia atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 1IPTF@117747,4NEPK@976,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane MAG.T22.56_00615 1267211.KI669560_gene2816 1.2e-14 85.5 Sphingobacteriia atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01165 Bacteria 1ITY0@117747,4NURW@976,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T22.56_00616 1122605.KB893626_gene2560 8.3e-34 150.2 Sphingobacteriia atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 Bacteria 1ISAN@117747,4NQKA@976,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T22.56_00617 1122605.KB893626_gene2559 1.9e-50 205.7 Sphingobacteriia atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 Bacteria 1ITDM@117747,4NSNF@976,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T22.56_00618 1267211.KI669560_gene2813 6.4e-261 906.4 Sphingobacteriia atpA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10975 Bacteria 1IP4E@117747,4NFZW@976,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit MAG.T22.56_00619 1296416.JACB01000029_gene4248 3.5e-23 114.8 Aquimarina phnO GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019634,GO:0019637,GO:0033051,GO:0044237,GO:0044424,GO:0044464,GO:0071704,GO:1901564 ko:K09994 ko00440,map00440 R11479 RC00096 ko00000,ko00001,ko01000 Bacteria 1I9KP@117743,2YJJU@290174,4NSKG@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.56_00621 762903.Pedsa_1437 1.3e-282 978.8 Sphingobacteriia Bacteria 1IPU6@117747,4NFIY@976,COG0457@1,COG0457@2 NA|NA|NA S Peptidase family M49 MAG.T22.56_00623 485918.Cpin_2036 0.0 1117.1 Sphingobacteriia lon 3.4.21.53 ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1IQDQ@117747,4NE1G@976,COG0466@1,COG0466@2 NA|NA|NA O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner MAG.T22.56_00624 485918.Cpin_0240 4.8e-41 174.9 Bacteroidetes Bacteria 2DICZ@1,32UAY@2,4NU7D@976 NA|NA|NA MAG.T22.56_00625 485918.Cpin_0452 9.5e-65 254.2 Sphingobacteriia Bacteria 1IQ9Z@117747,4NEX3@976,COG0526@1,COG0526@2 NA|NA|NA O Domain of unknown function (DUF4369) MAG.T22.56_00626 755732.Fluta_2711 1.5e-42 180.3 Cryomorphaceae Bacteria 1IHII@117743,2AXDY@1,2PB08@246874,31PDA@2,4PJH6@976 NA|NA|NA S HmuY protein MAG.T22.56_00627 715451.ambt_03035 4e-42 178.7 Alteromonadaceae 3.2.1.17 ko:K01185 ko00000,ko01000 Bacteria 1R3WD@1224,1SNI1@1236,46AKD@72275,COG3772@1,COG3772@2 NA|NA|NA S lysozyme MAG.T22.56_00629 546275.FUSPEROL_01630 5.2e-08 65.5 Fusobacteria Bacteria 37AI5@32066,COG2849@1,COG2849@2 NA|NA|NA S MORN repeat variant MAG.T22.56_00630 1267211.KI669560_gene1169 1e-255 889.0 Sphingobacteriia atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 1IPG7@117747,4NF1Q@976,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits MAG.T22.56_00631 1123248.KB893385_gene4773 9.5e-26 122.5 Sphingobacteriia atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1ITVV@117747,4NUYG@976,COG0355@1,COG0355@2 NA|NA|NA C ATP synthase MAG.T22.56_00633 1396418.BATQ01000140_gene3219 1.8e-11 74.7 Bacteria ko:K07729 ko00000,ko03000 Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding MAG.T22.56_00634 1122176.KB903538_gene1506 1.1e-126 460.7 Sphingobacteriia wbbL ko:K07011 ko00000 Bacteria 1IV9F@117747,4NFW5@976,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.56_00639 1121904.ARBP01000008_gene3375 3.6e-144 518.5 Cytophagia Bacteria 47K44@768503,4NFKR@976,COG4636@1,COG4636@2 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T22.56_00640 926562.Oweho_2626 1.1e-168 600.1 Cryomorphaceae ko:K07093 ko00000 Bacteria 1IESW@117743,2PBJA@246874,4NJ5V@976,COG3211@1,COG3211@2 NA|NA|NA S Bacterial protein of unknown function (DUF839) MAG.T22.56_00641 1121904.ARBP01000008_gene3377 1.4e-166 593.2 Cytophagia 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 47KXQ@768503,4NE50@976,COG1858@1,COG1858@2 NA|NA|NA C cytochrome c peroxidase MAG.T22.56_00642 313606.M23134_04012 1.2e-50 207.2 Cytophagia Bacteria 47Y2C@768503,4NMUN@976,COG0729@1,COG0729@2 NA|NA|NA M Surface antigen MAG.T22.56_00644 1267211.KI669560_gene723 4.4e-27 128.3 Bacteroidetes Bacteria 4NJW3@976,COG2197@1,COG2197@2 NA|NA|NA T Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.56_00646 762903.Pedsa_2526 2.9e-97 362.1 Sphingobacteriia hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 1IR75@117747,4NFEE@976,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound MAG.T22.56_00648 485918.Cpin_0487 6e-27 128.3 Sphingobacteriia Bacteria 1IUMD@117747,2CEK0@1,321UV@2,4NUC9@976 NA|NA|NA S Domain of unknown function (DUF4271) MAG.T22.56_00649 485918.Cpin_0486 1.5e-96 359.4 Sphingobacteriia hemD 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPP4@117747,4NEQ3@976,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase MAG.T22.56_00650 925409.KI911562_gene1153 3.9e-178 631.7 Sphingobacteriia yyaL ko:K06888 ko00000 Bacteria 1IQ72@117747,4NFE2@976,COG1331@1,COG1331@2 NA|NA|NA O COG1331 Highly conserved protein containing a thioredoxin domain MAG.T22.56_00651 485918.Cpin_0483 1.2e-124 453.4 Sphingobacteriia gldK Bacteria 1IP8A@117747,4NGY2@976,COG1262@1,COG1262@2 NA|NA|NA S PFAM Formylglycine-generating sulfatase enzyme MAG.T22.56_00652 485918.Cpin_0481 1.6e-50 206.5 Sphingobacteriia gldL Bacteria 1ISRG@117747,28IG3@1,2Z8HM@2,4NFJR@976 NA|NA|NA S TIGRFAM gliding motility-associated protein GldL MAG.T22.56_00653 485918.Cpin_0480 9.8e-89 334.3 Sphingobacteriia gldM Bacteria 1IR4A@117747,4PKZS@976,COG4219@1,COG4219@2 NA|NA|NA KT Gliding motility-associated protein GldM MAG.T22.56_00654 485918.Cpin_0479 3e-53 215.7 Sphingobacteriia gldN Bacteria 1IQ08@117747,28H74@1,2Z7JF@2,4NFR0@976 NA|NA|NA S TIGRFAM gliding motility associated MAG.T22.56_00655 485918.Cpin_1245 8.6e-97 360.1 Sphingobacteriia Bacteria 1IS3D@117747,4NF47@976,COG3170@1,COG3170@2 NA|NA|NA NU Protein of unknown function (DUF3108) MAG.T22.56_00656 485918.Cpin_1244 8e-41 174.5 Sphingobacteriia mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1IP3F@117747,4NI8Y@976,COG0392@1,COG0392@2 NA|NA|NA S Lysylphosphatidylglycerol synthase TM region MAG.T22.56_00657 700598.Niako_6930 1.9e-47 195.7 Sphingobacteriia ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1ISJU@117747,4NDV6@976,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group MAG.T22.56_00658 471854.Dfer_0398 4.8e-40 171.4 Cytophagia Bacteria 2DG7I@1,32U6S@2,47XS1@768503,4NUFD@976 NA|NA|NA MAG.T22.56_00659 485918.Cpin_1242 3.6e-75 288.1 Sphingobacteriia Bacteria 1IXKQ@117747,4NM5Q@976,COG0745@1,COG0745@2 NA|NA|NA K Two component transcriptional regulator, winged helix family MAG.T22.56_00660 485918.Cpin_6900 1.5e-72 280.0 Sphingobacteriia ko:K06076 ko00000,ko02000 1.B.9 Bacteria 1IQ3Y@117747,4NIU4@976,COG2067@1,COG2067@2 NA|NA|NA I protein CHP03519, membrane, Bacteroidetes MAG.T22.56_00661 700598.Niako_4480 2.2e-246 860.1 Sphingobacteriia 3.2.1.91 ko:K19668 ko00500,ko01100,ko02020,map00500,map01100,map02020 R02886,R11308 RC00799 ko00000,ko00001,ko01000 GH6 Bacteria 1IW61@117747,4NPDM@976,COG3291@1,COG3291@2 NA|NA|NA G PFAM PKD domain MAG.T22.56_00662 700598.Niako_0353 5e-96 357.5 Sphingobacteriia pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ0U@117747,4NF4Z@976,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate MAG.T22.56_00663 485918.Cpin_4041 4.4e-159 568.2 Sphingobacteriia ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1IRBF@117747,4NFT5@976,COG4166@1,COG4166@2 NA|NA|NA E PFAM Bacterial extracellular solute-binding proteins, family 5 Middle MAG.T22.56_00664 431947.PGN_1628 3.1e-93 348.6 Porphyromonadaceae ykcC 2.4.1.83 ko:K00721,ko:K20534 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 22Y10@171551,2FMW6@200643,4NGGM@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.56_00665 700598.Niako_5074 4.8e-177 627.5 Sphingobacteriia phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1IQZJ@117747,4NEDW@976,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase MAG.T22.56_00666 1123248.KB893337_gene2406 4.4e-230 803.9 Sphingobacteriia comM ko:K07391 ko00000 Bacteria 1INNX@117747,4NE0G@976,COG0606@1,COG0606@2 NA|NA|NA O chelatase, subunit chli MAG.T22.56_00667 383381.EH30_11370 1.8e-18 99.8 Sphingomonadales Bacteria 1MV2W@1224,2K2Y2@204457,2TRT8@28211,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_00668 391587.KAOT1_08849 4.8e-52 211.8 Flavobacteriia Bacteria 1I2DF@117743,29ZGM@1,30MGC@2,4NNY9@976 NA|NA|NA MAG.T22.56_00669 1267211.KI669560_gene738 5.1e-86 324.3 Sphingobacteriia paaG GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 iECO103_1326.ECO103_1531,iJN746.PP_3283,iYL1228.KPN_01475 Bacteria 1IV58@117747,4NHRF@976,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T22.56_00670 1229276.DI53_2927 3.7e-116 424.9 Sphingobacteriia Bacteria 1IPCN@117747,4NFYF@976,COG1819@1,COG1819@2 NA|NA|NA CG Glycosyl transferase family 1 MAG.T22.56_00671 143224.JQMD01000002_gene3015 4.7e-104 384.4 Flavobacteriia lpxH 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1HY0C@117743,4NFD8@976,COG2908@1,COG2908@2 NA|NA|NA S Phosphoesterase MAG.T22.56_00672 925409.KI911562_gene472 2.6e-115 421.8 Sphingobacteriia metH 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1IR6C@117747,4NFRF@976,COG0646@1,COG0646@2 NA|NA|NA E Methionine synthase MAG.T22.56_00673 485918.Cpin_6975 1.8e-120 439.1 Sphingobacteriia mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1IQU9@117747,4NE0T@976,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan MAG.T22.56_00674 1123248.KB893329_gene4487 7.4e-165 587.0 Sphingobacteriia murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1INPJ@117747,4NEFF@976,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) MAG.T22.56_00675 925409.KI911562_gene107 8.6e-117 427.2 Sphingobacteriia ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1IPWG@117747,4NFIM@976,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T22.56_00676 485918.Cpin_6978 7.1e-118 430.6 Sphingobacteriia murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1IPF4@117747,4NE6D@976,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) MAG.T22.56_00677 485918.Cpin_6979 1.3e-169 602.8 Sphingobacteriia murC 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1INTF@117747,4NE1V@976,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family MAG.T22.56_00678 700598.Niako_7325 2.7e-35 156.4 Sphingobacteriia ftsQ ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1IRV2@117747,4NGPN@976,COG1589@1,COG1589@2 NA|NA|NA M Cell division protein MAG.T22.56_00679 485918.Cpin_6981 4e-166 591.3 Sphingobacteriia ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1IQJQ@117747,4NE0V@976,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring MAG.T22.56_00680 485918.Cpin_6982 8.8e-160 570.5 Sphingobacteriia ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1IR5B@117747,4NF8N@976,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity MAG.T22.56_00681 1313421.JHBV01000027_gene1773 7.3e-07 60.1 Bacteroidetes Bacteria 2EIBB@1,33C2R@2,4NYRT@976 NA|NA|NA MAG.T22.56_00682 1227739.Hsw_2447 4.5e-206 724.9 Cytophagia 3.1.3.8 ko:K01083 ko00562,map00562 R03371 RC00078 ko00000,ko00001,ko01000 Bacteria 47KH5@768503,4NGDH@976,COG2356@1,COG2356@2,COG3391@1,COG3391@2 NA|NA|NA M alkaline phosphatase MAG.T22.56_00684 1267211.KI669560_gene2683 2.4e-56 225.3 Sphingobacteriia rpoE ko:K03088 ko00000,ko03021 Bacteria 1INYP@117747,4NF93@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_00685 700598.Niako_5589 2.7e-49 202.2 Sphingobacteriia rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1INQF@117747,4NE2S@976,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit MAG.T22.56_00686 760192.Halhy_0269 5.1e-79 300.8 Sphingobacteriia Bacteria 1IQFD@117747,4NFMT@976,COG1657@1,COG1657@2 NA|NA|NA I Domain of unknown function (DUF4159) MAG.T22.56_00687 1121904.ARBP01000004_gene1077 2.5e-65 256.1 Cytophagia Bacteria 47PB0@768503,4NFD3@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_00689 1111069.TCCBUS3UF1_2000 4.4e-15 87.4 Deinococcus-Thermus isdG 1.14.99.48,1.14.99.57 ko:K07145,ko:K21481 ko00860,ko01110,map00860,map01110 R10468,R10510 RC03185 ko00000,ko00001,ko01000 Bacteria 1WK6V@1297,COG2329@1,COG2329@2 NA|NA|NA S involved in biosynthesis of extracellular polysaccharides MAG.T22.56_00690 485918.Cpin_7095 5.7e-47 194.5 Sphingobacteriia porT Bacteria 1ISMS@117747,2C52N@1,2Z7U1@2,4NEZW@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.56_00691 1239962.C943_02440 5.2e-37 160.6 Bacteroidetes 3.1.21.7 ko:K05982,ko:K07452 ko00000,ko01000,ko02048,ko03400 Bacteria 4NZHS@976,COG3695@1,COG3695@2 NA|NA|NA L enzyme binding MAG.T22.56_00692 485918.Cpin_0867 3.3e-119 434.9 Sphingobacteriia metF 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQZ5@117747,4NDY0@976,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase MAG.T22.56_00693 485918.Cpin_0868 3.4e-111 407.9 Sphingobacteriia lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 1IQQ1@117747,4NDUG@976,COG1137@1,COG1137@2 NA|NA|NA S ABC transporter MAG.T22.56_00694 485918.Cpin_0869 5.6e-198 697.2 Sphingobacteriia Bacteria 1INYG@117747,4PKJY@976,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM GH3 auxin-responsive promoter MAG.T22.56_00695 880071.Fleli_3570 1.1e-69 270.0 Cytophagia ko:K07090 ko00000 Bacteria 47RU3@768503,4NFTT@976,COG0730@1,COG0730@2 NA|NA|NA S PFAM Sulfite exporter TauE SafE MAG.T22.56_00696 929562.Emtol_0844 1.4e-15 89.4 Cytophagia Bacteria 2AXFQ@1,31PF8@2,47SZR@768503,4NQN3@976 NA|NA|NA MAG.T22.56_00697 485918.Cpin_7093 3.9e-73 281.2 Sphingobacteriia engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1ISQ4@117747,4NEA9@976,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation MAG.T22.56_00698 700598.Niako_3669 1.1e-100 373.6 Sphingobacteriia clsB GO:0003674,GO:0003824,GO:0004620,GO:0004630,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016298,GO:0016740,GO:0016772,GO:0016780,GO:0016787,GO:0016788,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 iECED1_1282.ECED1_0754 Bacteria 1J0D9@117747,4P0CZ@976,COG1502@1,COG1502@2 NA|NA|NA I Phospholipase D. Active site motifs. MAG.T22.56_00699 1123248.KB893316_gene4610 3.9e-102 378.3 Sphingobacteriia XCC0762 ko:K07038 ko00000 Bacteria 1IYQQ@117747,4NFBT@976,COG1988@1,COG1988@2 NA|NA|NA S LexA-binding, inner membrane-associated putative hydrolase MAG.T22.56_00701 700598.Niako_5143 7.7e-106 391.0 Sphingobacteriia Bacteria 1IV5S@117747,4NH6T@976,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T22.56_00702 714943.Mucpa_4009 1.1e-52 213.4 Sphingobacteriia ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1ISA7@117747,4NFJI@976,COG3201@1,COG3201@2 NA|NA|NA H TIGRFAM Nicotinamide mononucleotide transporter PnuC MAG.T22.56_00703 929562.Emtol_1029 1e-46 193.4 Cytophagia 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 47RME@768503,4NQ5M@976,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily MAG.T22.56_00704 485918.Cpin_0719 7.7e-54 216.9 Sphingobacteriia nadR Bacteria 1ISIF@117747,4NFNZ@976,COG3172@1,COG3172@2 NA|NA|NA H ATPase kinase involved in NAD metabolism MAG.T22.56_00705 485918.Cpin_0717 1.1e-80 306.2 Sphingobacteriia yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1IQWM@117747,4NDZR@976,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family MAG.T22.56_00706 485918.Cpin_1066 3.5e-267 927.5 Sphingobacteriia ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K04096 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1IQAI@117747,4NE2X@976,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T22.56_00707 504472.Slin_4013 1e-13 83.2 Bacteroidetes Bacteria 2EHXW@1,33BPD@2,4NYG9@976 NA|NA|NA MAG.T22.56_00708 700598.Niako_6019 0.0 1382.9 Sphingobacteriia metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13,2.1.1.245,2.1.1.258 ko:K00197,ko:K00548,ko:K15023 ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230 M00017,M00357,M00377,M00422 R00946,R02289,R09096,R09365,R10219,R10243 RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977 ko00000,ko00001,ko00002,ko01000 Bacteria 1J0KU@117747,4PKI8@976,COG1410@1,COG1410@2 NA|NA|NA E B12 binding domain MAG.T22.56_00709 485918.Cpin_0853 8e-32 144.1 Sphingobacteriia 3.6.1.27 ko:K12977,ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01005,ko01011 Bacteria 1IUI6@117747,4NUPJ@976,COG0671@1,COG0671@2 NA|NA|NA I phosphoesterase, PA-phosphatase related MAG.T22.56_00710 1123248.KB893323_gene1642 7.1e-229 799.7 Sphingobacteriia ahcY GO:0000096,GO:0000097,GO:0000098,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0035375,GO:0035635,GO:0036094,GO:0036293,GO:0040007,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0070482,GO:0071268,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 1IQTE@117747,4NEKE@976,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine MAG.T22.56_00711 1408813.AYMG01000017_gene5519 4.1e-84 318.2 Sphingobacteriia dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1INT7@117747,4NFP9@976,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) MAG.T22.56_00712 485918.Cpin_6634 1.3e-131 476.1 Sphingobacteriia accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN678.accA,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 Bacteria 1IP0K@117747,4NEVU@976,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA MAG.T22.56_00713 865937.Gilli_3386 5.4e-154 550.8 Gillisia Bacteria 1HZ4T@117743,2P7FZ@244698,4NEN9@976,COG0477@1,COG2814@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T22.56_00714 760192.Halhy_1754 6.2e-57 227.3 Sphingobacteriia Bacteria 1IXYV@117747,4NSMK@976,COG0664@1,COG0664@2 NA|NA|NA T cyclic nucleotide-binding domain MAG.T22.56_00715 700598.Niako_4610 1e-286 992.3 Sphingobacteriia yhcR 3.1.3.5,3.6.1.45 ko:K01081,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_4246,iECS88_1305.ECS88_4396,iLF82_1304.LF82_624 Bacteria 1IVAT@117747,4NESM@976,COG0737@1,COG0737@2 NA|NA|NA F COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase MAG.T22.56_00716 1123248.KB893326_gene1441 3.6e-113 414.8 Sphingobacteriia petA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009512,GO:0009579,GO:0016491,GO:0016667,GO:0016669,GO:0032991,GO:0044424,GO:0044436,GO:0044464,GO:0050338,GO:0055114,GO:0070069 1.8.2.2 ko:K02634,ko:K19713 ko00195,ko01100,map00195,map01100 M00162 ko00000,ko00001,ko00002,ko00194,ko01000 Bacteria 1IRZ3@117747,4NGIH@976,COG3258@1,COG3258@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III MAG.T22.56_00717 1123248.KB893326_gene1438 5.7e-76 290.4 Sphingobacteriia ko:K07112 ko00000 Bacteria 1IS9I@117747,4NQ9C@976,COG2391@1,COG2391@2 NA|NA|NA S PFAM YeeE YedE family (DUF395) MAG.T22.56_00718 1123248.KB893326_gene1439 6.3e-78 297.0 Sphingobacteriia ko:K07112 ko00000 Bacteria 1IS2D@117747,4NM6E@976,COG2391@1,COG2391@2 NA|NA|NA S PFAM YeeE YedE family (DUF395) MAG.T22.56_00719 1120951.AUBG01000019_gene1720 1.4e-37 163.3 Flavobacteriia ko:K02477 ko00000,ko02022 Bacteria 1HYS4@117743,4NGX6@976,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain MAG.T22.56_00720 688270.Celal_4005 2.4e-46 194.5 Cellulophaga Bacteria 1FAH3@104264,1HX37@117743,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2 NA|NA|NA T PFAM Signal transduction histidine kinase, internal region MAG.T22.56_00724 313595.P700755_003235 2.6e-81 309.7 Flavobacteriia Bacteria 1I4B1@117743,4NF1M@976,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T22.56_00725 388413.ALPR1_13225 1.4e-16 91.7 Cytophagia ko:K07729 ko00000,ko03000 Bacteria 47S1R@768503,4NV53@976,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.56_00728 1250278.JQNQ01000001_gene2744 2.2e-10 72.4 Flavobacteriia Bacteria 1I1QQ@117743,2DBZ0@1,2ZBZ5@2,4NMKQ@976 NA|NA|NA MAG.T22.56_00729 1089548.KI783301_gene839 1.3e-57 229.9 Bacillales incertae sedis Bacteria 1TSND@1239,3WF8E@539002,4HAU2@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.56_00730 1121481.AUAS01000015_gene2184 4.2e-29 136.3 Cytophagia Bacteria 47N3J@768503,4NKED@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_00732 1123248.KB893370_gene4979 4.3e-31 141.4 Sphingobacteriia ko:K03088 ko00000,ko03021 Bacteria 1ISH7@117747,4NQCH@976,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog MAG.T22.56_00736 714943.Mucpa_5472 2.6e-52 211.8 Sphingobacteriia 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1ISAM@117747,4NQEC@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_00737 153721.MYP_2859 2.5e-30 138.3 Cytophagia Bacteria 47R0R@768503,4NSDH@976,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.56_00738 991.IW20_20205 2e-61 242.3 Flavobacterium Bacteria 1I10P@117743,2NUSY@237,4NJ5M@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase MAG.T22.56_00739 1499967.BAYZ01000040_gene2239 7.3e-43 181.8 Bacteria 3.4.16.4 ko:K01286 ko00000,ko01000 Bacteria COG1680@1,COG1680@2 NA|NA|NA V peptidase activity MAG.T22.56_00741 760192.Halhy_1874 2.4e-15 89.0 Sphingobacteriia Bacteria 1IPRK@117747,28HMX@1,2Z7WB@2,4NFY2@976 NA|NA|NA MAG.T22.56_00742 929556.Solca_3924 3.1e-190 671.8 Sphingobacteriia pepN Bacteria 1IRPT@117747,4NFT0@976,COG0308@1,COG0308@2 NA|NA|NA E Leukotriene A4 hydrolase, C-terminal MAG.T22.56_00743 760192.Halhy_2333 2.6e-116 425.6 Sphingobacteriia sotB Bacteria 1IPF0@117747,4NESW@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.56_00745 1185876.BN8_02321 4e-57 228.0 Cytophagia Bacteria 47PAQ@768503,4NN09@976,COG0664@1,COG0664@2 NA|NA|NA T Transcriptional regulator, Crp Fnr family MAG.T22.56_00746 700598.Niako_7037 4.2e-34 151.4 Sphingobacteriia Bacteria 1ITXI@117747,4NP2C@976,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T22.56_00747 1089547.KB913013_gene1640 9.5e-311 1072.4 Cytophagia maeB GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 ko:K00027,ko:K00029,ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020 M00169,M00172,M00357,M00579 R00214,R00216,R00230,R00921 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1637 Bacteria 47JSR@768503,4NFUJ@976,COG0280@1,COG0280@2,COG0281@1,COG0281@2 NA|NA|NA C Phosphate acetyl butaryl transferase MAG.T22.56_00748 1267211.KI669560_gene1339 2e-129 469.2 Sphingobacteriia yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07007 ko00000 Bacteria 1IP0F@117747,4NFME@976,COG2081@1,COG2081@2 NA|NA|NA S HI0933 family MAG.T22.56_00749 1123277.KB893212_gene9 2.4e-105 389.0 Cytophagia fimY ko:K08088 ko00000 Bacteria 47NH3@768503,4NES9@976,COG2197@1,COG2197@2 NA|NA|NA KT AAA domain MAG.T22.56_00750 1122226.AUHX01000014_gene522 3.2e-133 482.3 Bacteroidetes Bacteria 4PPPE@976,COG3950@1,COG3950@2 NA|NA|NA S AAA ATPase domain MAG.T22.56_00751 468059.AUHA01000010_gene2827 2.6e-17 95.1 Bacteria Bacteria 2CANF@1,2ZEC5@2 NA|NA|NA MAG.T22.56_00752 700598.Niako_6491 2e-104 386.0 Sphingobacteriia dppC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1IQI5@117747,4NGTQ@976,COG1173@1,COG1173@2 NA|NA|NA EP PFAM Binding-protein-dependent transport system inner membrane component MAG.T22.56_00753 491205.JARQ01000001_gene754 1.7e-129 469.5 Chryseobacterium pgcp Bacteria 1HXV2@117743,3ZPM8@59732,4NE66@976,COG2234@1,COG2234@2 NA|NA|NA S Peptidase, M28 MAG.T22.56_00754 1229276.DI53_2454 3.4e-12 77.8 Bacteroidetes Bacteria 4NXZT@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_00755 485918.Cpin_1189 1.5e-147 529.3 Sphingobacteriia bshA GO:0003674,GO:0003824,GO:0016740,GO:0016757 ko:K00754 ko00000,ko01000 GT4 Bacteria 1IPP6@117747,4NFPA@976,COG0438@1,COG0438@2 NA|NA|NA M N-acetyl-alpha-D-glucosaminyl L-malate synthase MAG.T22.56_00756 485918.Cpin_1032 5.2e-51 206.8 Sphingobacteriia rnhA 3.1.26.4,4.1.1.44 ko:K01607,ko:K03469 ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030 R03470 RC00938 ko00000,ko00001,ko01000,ko03032 Bacteria 1ISNQ@117747,4NNRB@976,COG0599@1,COG0599@2 NA|NA|NA S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T22.56_00757 925409.KI911562_gene2936 8e-57 226.5 Sphingobacteriia fkpB 5.2.1.8 ko:K03772,ko:K03773 ko00000,ko01000,ko03110 Bacteria 1IXT3@117747,4NDW4@976,COG0545@1,COG0545@2 NA|NA|NA O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MAG.T22.56_00758 1123248.KB893381_gene1046 1.6e-72 278.9 Sphingobacteriia ko:K07095 ko00000 Bacteria 1IRXF@117747,4NM4G@976,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase MAG.T22.56_00759 1123248.KB893315_gene3130 1.1e-25 123.2 Sphingobacteriia 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1IYVQ@117747,4NV0H@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_00760 929556.Solca_4124 9.4e-38 163.3 Sphingobacteriia Bacteria 1IYJ7@117747,4NPKI@976,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein MAG.T22.56_00761 485918.Cpin_5469 2.7e-51 208.0 Sphingobacteriia ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1ISC1@117747,4NM5B@976,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate MAG.T22.56_00762 700598.Niako_2016 1.7e-97 362.8 Sphingobacteriia nrnA GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 ko:K00974,ko:K06881 ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013 R00188,R00508,R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 1IPG0@117747,4NEXE@976,COG0618@1,COG0618@2 NA|NA|NA S phosphoesterase RecJ domain protein MAG.T22.56_00763 700598.Niako_6428 5.3e-166 590.5 Sphingobacteriia gcvT 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPCZ@117747,4NF7S@976,COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T22.56_00764 1122176.KB903531_gene2958 3.9e-68 266.2 Bacteroidetes Bacteria 4NPS7@976,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family MAG.T22.56_00765 485918.Cpin_0884 1e-105 389.8 Sphingobacteriia pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1IPN7@117747,4NE8Z@976,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP MAG.T22.56_00766 925409.KI911562_gene2874 1.7e-156 558.9 Sphingobacteriia GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1INMN@117747,4NFMA@976,COG4867@1,COG4867@2 NA|NA|NA S von Willebrand factor, type A MAG.T22.56_00767 485918.Cpin_0897 8.9e-46 189.9 Sphingobacteriia ko:K07071 ko00000 Bacteria 1ISKP@117747,4NQJG@976,COG4276@1,COG4276@2 NA|NA|NA S SRPBCC domain-containing protein MAG.T22.56_00768 1267211.KI669560_gene804 3.6e-72 278.5 Sphingobacteriia ycgE ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1IS5U@117747,4NERC@976,COG0789@1,COG0789@2,COG5012@1,COG5012@2 NA|NA|NA K MerR family MAG.T22.56_00769 1267211.KI669560_gene805 3.5e-48 198.0 Sphingobacteriia sigR_3 ko:K03088 ko00000,ko03021 Bacteria 1IPYA@117747,4NMM3@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_00770 313606.M23134_07221 8.3e-178 630.2 Cytophagia crtI 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 ko:K10027,ko:K20611 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 47JMY@768503,4NF7K@976,COG1233@1,COG1233@2 NA|NA|NA Q TIGRFAM phytoene desaturase MAG.T22.56_00771 1267211.KI669560_gene807 3.9e-36 157.5 Sphingobacteriia crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10208 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1IP80@117747,4NEIK@976,COG1562@1,COG1562@2 NA|NA|NA I Squalene phytoene synthase MAG.T22.56_00772 1267211.KI669560_gene807 7.4e-39 166.8 Sphingobacteriia crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10208 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1IP80@117747,4NEIK@976,COG1562@1,COG1562@2 NA|NA|NA I Squalene phytoene synthase MAG.T22.56_00773 485918.Cpin_4731 1.4e-50 206.1 Sphingobacteriia idi GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576 4.1.1.33,5.3.3.2 ko:K01597,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01121,R01123 RC00453,RC00455 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISDP@117747,4NFJV@976,COG1443@1,COG1443@2 NA|NA|NA I TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1 MAG.T22.56_00774 1267211.KI669560_gene809 2.3e-135 489.2 Sphingobacteriia crtD 1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9 ko:K01854,ko:K09845,ko:K10027 ko00052,ko00520,ko00906,ko01100,ko01110,map00052,map00520,map00906,map01100,map01110 R00505,R04787,R04798,R04800,R07517,R07520,R07523,R07534,R09009,R09691,R09692 RC00317,RC01214,RC02080,RC02088,RC02396,RC02605 ko00000,ko00001,ko01000 Bacteria 1IR1U@117747,4NG7V@976,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase MAG.T22.56_00775 700598.Niako_5799 1.7e-82 313.5 Sphingobacteriia Bacteria 1ISIT@117747,2DB82@1,2Z7PX@2,4NEW5@976 NA|NA|NA MAG.T22.56_00776 1122605.KB893625_gene2339 1e-39 170.6 Sphingobacteriia fjo14 ko:K22205 ko00000,ko01000 Bacteria 1IQEU@117747,4NG9Y@976,COG1912@1,COG1912@2 NA|NA|NA S S-adenosyl-l-methionine hydroxide adenosyltransferase MAG.T22.56_00777 1296415.JACC01000036_gene1179 3.2e-25 120.9 Aquimarina 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1I40Y@117743,2YJYM@290174,4NSV0@976,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase MAG.T22.56_00778 1267211.KI669560_gene2794 1.5e-49 202.2 Sphingobacteriia hit ko:K02503 ko00000,ko04147 Bacteria 1ISWH@117747,4NQ4X@976,COG0537@1,COG0537@2 NA|NA|NA FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family MAG.T22.56_00779 485918.Cpin_1240 9.7e-56 223.0 Sphingobacteriia greA ko:K03624 ko00000,ko03021 Bacteria 1IS01@117747,4NNH6@976,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides MAG.T22.56_00780 1122176.KB903565_gene3246 1.5e-67 263.5 Sphingobacteriia Bacteria 1IYUI@117747,4NWE8@976,COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transport protein MAG.T22.56_00781 1453500.AT05_08795 4e-211 742.3 Bacteroidetes Bacteria 2E09V@1,32VXB@2,4NY12@976 NA|NA|NA MAG.T22.56_00782 1453500.AT05_08790 8.3e-14 83.2 Bacteroidetes Bacteria 4NTQD@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T22.56_00784 700598.Niako_1568 4.3e-240 838.2 Sphingobacteriia smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 1IPD0@117747,4NHWQ@976,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T22.56_00785 1123248.KB893317_gene4262 3.9e-33 147.1 Sphingobacteriia smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 1IPD0@117747,4NHWQ@976,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T22.56_00786 880071.Fleli_1987 2.1e-50 206.5 Cytophagia Bacteria 47JPN@768503,4NPI2@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_00788 1123248.KB893314_gene3624 8e-247 859.8 Sphingobacteriia hscA GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010467,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051604,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0097428,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1903506,GO:1990230,GO:1990234,GO:2001141 ko:K04043,ko:K04044 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33,1.A.33.1 Bacteria 1IQ1C@117747,4NEHZ@976,COG0443@1,COG0443@2 NA|NA|NA O heat shock protein 70 MAG.T22.56_00789 485918.Cpin_3064 1.3e-115 423.3 Sphingobacteriia lysC 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ3C@117747,4NF0M@976,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family MAG.T22.56_00790 1123248.KB893331_gene3749 1e-176 626.3 Sphingobacteriia 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1IPI0@117747,4NFPR@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.56_00791 1123248.KB893326_gene1423 1e-48 201.4 Sphingobacteriia lptD Bacteria 1IP5G@117747,4NDU3@976,COG1452@1,COG1452@2 NA|NA|NA M OstA-like protein MAG.T22.56_00792 485918.Cpin_6192 3.4e-39 169.1 Sphingobacteriia ttg2C ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1IQZY@117747,4NHT9@976,COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents periplasmic component MAG.T22.56_00793 485918.Cpin_0419 5.6e-166 592.0 Sphingobacteriia ko:K03641,ko:K07277 ko00000,ko02000,ko03029 1.B.33,2.C.1.2 Bacteria 1J0KM@117747,4NERT@976,COG0823@1,COG0823@2,COG4775@1,COG4775@2 NA|NA|NA M PFAM WD40-like beta Propeller MAG.T22.56_00794 929713.NIASO_12450 9.4e-62 243.4 Sphingobacteriia ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1J079@117747,4NE2Y@976,COG0491@1,COG0491@2 NA|NA|NA P beta-lactamase domain protein MAG.T22.56_00795 700598.Niako_5732 6.6e-27 128.3 Bacteria 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria COG0265@1,COG0265@2 NA|NA|NA O serine-type endopeptidase activity MAG.T22.56_00796 485918.Cpin_0597 1e-80 306.6 Sphingobacteriia comB GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPNP@117747,4NG1A@976,COG2045@1,COG2045@2 NA|NA|NA H Belongs to the ComB family MAG.T22.56_00797 485918.Cpin_2046 1.6e-31 141.7 Sphingobacteriia rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IT8M@117747,4NS7T@976,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family MAG.T22.56_00798 1122621.ATZA01000048_gene982 5e-26 123.6 Sphingobacteriia rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISXI@117747,4NSHE@976,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 MAG.T22.56_00799 700598.Niako_0577 3.8e-212 744.2 Sphingobacteriia Bacteria 1IP9C@117747,4PKJA@976,COG1541@1,COG1541@2 NA|NA|NA H GH3 auxin-responsive promoter MAG.T22.56_00800 485918.Cpin_4069 3.2e-121 443.0 Bacteroidetes Bacteria 4PKNV@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent receptor MAG.T22.56_00801 700598.Niako_4359 8.9e-62 243.8 Sphingobacteriia Bacteria 1IQC4@117747,2C8XG@1,2Z7PK@2,4NEU8@976 NA|NA|NA S Protein of unknown function (DUF4197) MAG.T22.56_00802 679937.Bcop_0706 8.7e-40 171.8 Bacteroidaceae Bacteria 2FNHC@200643,4AKEY@815,4NEPG@976,COG5107@1,COG5107@2 NA|NA|NA A Psort location Cytoplasmic, score 8.96 MAG.T22.56_00803 1267211.KI669560_gene2539 1.8e-23 115.9 Bacteria Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis MAG.T22.56_00804 153721.MYP_1853 7.7e-242 844.0 Cytophagia dnaQ2 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 47UJ0@768503,4NIIR@976,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Exodeoxyribonuclease V, gamma subunit MAG.T22.56_00805 1121887.AUDK01000004_gene258 7.7e-74 285.4 Flavobacterium Bacteria 1HY1Z@117743,2NSS7@237,4NE8J@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.56_00806 1313301.AUGC01000010_gene899 1.8e-51 208.8 Bacteroidetes rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 4NNSU@976,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase MAG.T22.56_00807 1123248.KB893322_gene626 2.1e-69 269.2 Sphingobacteriia tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1INR5@117747,4NEKM@976,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes MAG.T22.56_00808 485918.Cpin_1934 9.4e-59 234.2 Sphingobacteriia htrA_1 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1IPPQ@117747,4NGA4@976,COG0265@1,COG0265@2 NA|NA|NA O peptidase S1 and S6 chymotrypsin Hap MAG.T22.56_00809 1122605.KB893625_gene1823 1.8e-40 172.6 Sphingobacteriia ko:K03088,ko:K03091 ko00000,ko03021 Bacteria 1IRKZ@117747,4NM40@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_00811 1122605.KB893646_gene47 2e-62 245.7 Sphingobacteriia Bacteria 1IQZH@117747,28H5J@1,2Z7I5@2,4NHK6@976 NA|NA|NA S Domain of unknown function (DUF4290) MAG.T22.56_00812 485918.Cpin_1015 6.4e-182 643.7 Sphingobacteriia murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1IPZR@117747,4NDV8@976,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine MAG.T22.56_00814 1121373.KB903652_gene1472 1.4e-33 151.0 Bacteroidetes Bacteria 4PPK0@976,COG3291@1,COG3291@2,COG5184@1,COG5184@2 NA|NA|NA G amine dehydrogenase activity MAG.T22.56_00815 1122179.KB890470_gene428 1.9e-36 160.6 Bacteroidetes Bacteria 4PPD5@976,COG5305@1,COG5305@2 NA|NA|NA S Membrane MAG.T22.56_00818 1121285.AUFK01000013_gene2527 2.5e-305 1054.3 Chryseobacterium paaN GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.77,1.2.1.91,3.3.2.12 ko:K02618,ko:K15514 ko00360,ko00362,ko01120,map00360,map00362,map01120 R09554,R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 iEC55989_1330.EC55989_1523,iECO111_1330.ECO111_1781,iECO26_1355.ECO26_1991 Bacteria 1HXAQ@117743,3ZNRY@59732,4NI68@976,COG1012@1,COG1012@2,COG2030@1,COG2030@2 NA|NA|NA CI Phenylacetic acid degradation protein PaaN MAG.T22.56_00819 755732.Fluta_1273 1e-54 221.1 Cryomorphaceae Bacteria 1HYN2@117743,2PC2Y@246874,4NRP7@976,COG4447@1,COG4447@2 NA|NA|NA S Photosynthesis system II assembly factor YCF48 MAG.T22.56_00820 1408433.JHXV01000001_gene668 8.1e-92 343.6 Cryomorphaceae 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 1HXB6@117743,2PA9D@246874,4NEH4@976,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T22.56_00821 391596.PBAL39_02710 7.4e-123 447.2 Sphingobacteriia rgpA ko:K12996 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1IPXH@117747,4NEJ6@976,COG0438@1,COG0438@2 NA|NA|NA M Domain of unknown function (DUF1972) MAG.T22.56_00822 700598.Niako_5571 6e-85 321.2 Bacteroidetes ko:K00786 ko00000,ko01000 Bacteria 4NMZ6@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_00823 714943.Mucpa_3258 2.2e-75 289.3 Sphingobacteriia Bacteria 1IT9V@117747,4PKM6@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.56_00824 1046627.BZARG_1638 1e-19 105.1 Flavobacteriia Bacteria 1I6CC@117743,2DQB6@1,335RR@2,4NV0W@976 NA|NA|NA MAG.T22.56_00825 714943.Mucpa_3256 6.1e-40 172.2 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process MAG.T22.56_00826 688270.Celal_1573 2.3e-19 103.6 Bacteria ko:K02847 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 Bacteria COG3307@1,COG3307@2 NA|NA|NA M -O-antigen MAG.T22.56_00827 391603.FBALC1_00330 7.1e-53 214.2 Flavobacteriia wcaJ ko:K03606 ko05111,map05111 ko00000,ko00001 Bacteria 1HXT6@117743,4NER4@976,COG2148@1,COG2148@2 NA|NA|NA M sugar transferase MAG.T22.56_00828 925409.KI911562_gene2539 4.4e-32 145.2 Bacteria Bacteria COG0589@1,COG0589@2 NA|NA|NA T AMP binding MAG.T22.56_00829 1267211.KI669560_gene226 7.9e-27 126.3 Sphingobacteriia sdpR ko:K03892 ko00000,ko03000 Bacteria 1IZ7N@117747,4NS8H@976,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T22.56_00830 925409.KI911562_gene2097 2e-119 435.6 Sphingobacteriia fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 iUTI89_1310.UTI89_C4836,ic_1306.c5329 Bacteria 1IQAD@117747,4NG06@976,COG0158@1,COG0158@2 NA|NA|NA G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 MAG.T22.56_00831 485918.Cpin_4695 2.7e-118 431.8 Sphingobacteriia corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1IWM4@117747,4NGM7@976,COG0598@1,COG0598@2 NA|NA|NA P Mg2 transporter protein, CorA family protein MAG.T22.56_00832 755732.Fluta_2321 2.4e-26 125.2 Cryomorphaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1I3JR@117743,2PB60@246874,4NR5C@976,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.56_00833 760192.Halhy_6179 1.7e-15 90.5 Bacteroidetes Bacteria 2CA1R@1,3391I@2,4NXBJ@976 NA|NA|NA MAG.T22.56_00834 485918.Cpin_6430 2.3e-289 1001.1 Sphingobacteriia dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1IPCI@117747,4NERF@976,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein MAG.T22.56_00836 485918.Cpin_6952 4e-28 131.3 Bacteroidetes dinB Bacteria 4NPSF@976,COG2318@1,COG2318@2 NA|NA|NA S Pfam DinB family MAG.T22.56_00837 925409.KI911562_gene1496 1.3e-144 519.6 Sphingobacteriia 4.4.1.11,4.4.1.8 ko:K01760,ko:K01761 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00654,R00782,R01286,R02408,R04770,R04941 RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 1IP3G@117747,4NJRK@976,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.56_00838 700598.Niako_7050 1e-157 563.1 Sphingobacteriia pcaF 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K00632,ko:K02615 ko00071,ko00072,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00360,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095,R09839 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IVK0@117747,4NE3Q@976,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T22.56_00839 1278073.MYSTI_00936 2.3e-123 448.7 Deltaproteobacteria 4.1.1.45,4.1.1.46 ko:K03392,ko:K14333 ko00362,ko00380,ko00627,ko01100,ko01120,map00362,map00380,map00627,map01100,map01120 M00038 R00821,R04323 RC00390,RC00779 ko00000,ko00001,ko00002,ko01000 Bacteria 1R5PG@1224,2WW88@28221,431I4@68525,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase MAG.T22.56_00840 1123277.KB893173_gene1687 1.6e-178 633.3 Cytophagia Bacteria 47JAS@768503,4P4MW@976,COG1629@1,COG1629@2 NA|NA|NA P TonB-dependent receptor MAG.T22.56_00841 760192.Halhy_1458 4.7e-116 426.0 Sphingobacteriia Bacteria 1J053@117747,4NJX0@976,COG3292@1,COG3292@2,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.56_00842 760192.Halhy_1457 6.2e-74 283.9 Sphingobacteriia Bacteria 1IVHE@117747,4NR4G@976,COG2197@1,COG2197@2 NA|NA|NA K COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.56_00845 485918.Cpin_2868 5.1e-34 151.0 Bacteroidetes IV02_27370 ko:K06940 ko00000 Bacteria 4P5VP@976,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T22.56_00848 485918.Cpin_2780 5.1e-205 721.1 Sphingobacteriia mutS2 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1IP8R@117747,4NFE6@976,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity MAG.T22.56_00851 485918.Cpin_6305 1.2e-19 104.0 Sphingobacteriia Bacteria 1IYEP@117747,4NN7U@976,COG1566@1,COG1566@2 NA|NA|NA V Protein of unknown function (DUF3667) MAG.T22.56_00852 649349.Lbys_1081 1.5e-155 556.2 Cytophagia ydcR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 2.7.7.65 ko:K00375,ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000,ko03000 Bacteria 47NBW@768503,4NGKQ@976,COG1167@1,COG1167@2 NA|NA|NA K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs MAG.T22.56_00853 1406840.Q763_09625 2.7e-65 255.8 Flavobacterium Bacteria 1HWKK@117743,2P065@237,4NGJR@976,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.56_00854 1406840.Q763_09640 3.3e-112 411.8 Flavobacterium ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iAF987.Gmet_2853,iYO844.BSU38550 Bacteria 1HY87@117743,2NTB0@237,4NEJY@976,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family MAG.T22.56_00855 649349.Lbys_1075 1.5e-37 162.5 Cytophagia Bacteria 47Y1I@768503,4PKSA@976,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.56_00856 1121287.AUMU01000005_gene3146 2e-63 248.8 Chryseobacterium Bacteria 1I1AG@117743,3ZPIY@59732,4NMJ9@976,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF1572) MAG.T22.56_00857 714943.Mucpa_2724 6.7e-20 103.6 Sphingobacteriia Bacteria 1IU65@117747,2EFPT@1,339FT@2,4NV1V@976 NA|NA|NA MAG.T22.56_00858 468059.AUHA01000002_gene940 3.9e-35 154.8 Sphingobacteriia ko:K03088 ko00000,ko03021 Bacteria 1J06I@117747,4NP02@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.56_00860 485918.Cpin_6618 9.9e-51 206.8 Bacteroidetes yniC GO:0000287,GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050084,GO:0050286,GO:0050308,GO:0050309 3.1.3.23 ko:K19270 ko00000,ko01000 Bacteria 4NID6@976,COG0637@1,COG0637@2 NA|NA|NA S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 MAG.T22.56_00861 1191523.MROS_1246 3.7e-161 574.7 Bacteria ko:K07263 ko00000,ko01000,ko01002 Bacteria COG0612@1,COG0612@2 NA|NA|NA L Peptidase, M16 MAG.T22.56_00862 1191523.MROS_1247 2.6e-169 602.4 Bacteria ko:K07263 ko00000,ko01000,ko01002 Bacteria COG0612@1,COG0612@2,COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) MAG.T22.56_00866 468059.AUHA01000006_gene2853 6.7e-141 506.9 Sphingobacteriia mdh 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 1IP11@117747,4NEJ7@976,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate MAG.T22.56_00867 1121895.Q765_01075 5.3e-12 78.2 Flavobacterium Bacteria 1IDXE@117743,2BVHW@1,2NZES@237,30Z9V@2,4PDF6@976 NA|NA|NA MAG.T22.56_00872 485918.Cpin_6777 1.3e-110 406.8 Sphingobacteriia Bacteria 1IT3V@117747,4NI1Z@976,COG1680@1,COG1680@2 NA|NA|NA V COGs COG1680 Beta-lactamase class C and other penicillin binding protein MAG.T22.56_00874 143224.JQMD01000002_gene1534 2.2e-88 332.4 Flavobacteriia Bacteria 1HZD2@117743,28HDX@1,2Z7QG@2,4NFID@976 NA|NA|NA MAG.T22.56_00875 531844.FIC_00770 9.6e-07 60.5 Flavobacteriia Bacteria 1I76I@117743,2EJJA@1,33DA8@2,4NXRS@976 NA|NA|NA S Peptidoglycan-binding protein LysM MAG.T22.56_00876 746697.Aeqsu_1797 2.2e-08 67.4 Flavobacteriia Bacteria 1HZTN@117743,4NJHN@976,COG1520@1,COG1520@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_00877 746697.Aeqsu_1797 1e-10 75.1 Flavobacteriia Bacteria 1HZTN@117743,4NJHN@976,COG1520@1,COG1520@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_00878 1121373.KB903632_gene508 1.3e-178 634.4 Cytophagia Bacteria 47Q36@768503,4NNUN@976,COG1520@1,COG1520@2 NA|NA|NA G Belongs to the glycosyl hydrolase 8 (cellulase D) family MAG.T22.56_00879 926556.Echvi_2895 8e-43 180.3 Cytophagia pagC ko:K07804 ko02020,map02020 ko00000,ko00001 Bacteria 47NZ9@768503,4NE33@976,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.56_00880 700598.Niako_3685 4.9e-24 117.9 Sphingobacteriia porQ Bacteria 1IXQD@117747,4NHNC@976,COG2067@1,COG2067@2 NA|NA|NA I penicillin-binding protein MAG.T22.56_00881 485918.Cpin_1175 1.5e-83 316.2 Sphingobacteriia terC ko:K05794 ko00000 Bacteria 1IQSJ@117747,4NGCD@976,COG0861@1,COG0861@2 NA|NA|NA P COG0861 Membrane protein TerC possibly involved in tellurium resistance MAG.T22.56_00882 1227739.Hsw_2017 1.8e-103 383.6 Cytophagia pepN1 Bacteria 47JW1@768503,4NG5Q@976,COG0308@1,COG0308@2 NA|NA|NA E Peptidase M1, membrane alanine aminopeptidase MAG.T22.56_00883 1356852.N008_18825 1.7e-117 430.3 Cytophagia pepN1 Bacteria 47JW1@768503,4NG5Q@976,COG0308@1,COG0308@2 NA|NA|NA E Peptidase M1, membrane alanine aminopeptidase MAG.T22.56_00885 1235813.JCM10003_3456 4.9e-14 84.0 Bacteroidaceae ko:K19449,ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2FVXQ@200643,4ASRH@815,4PA0W@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.56_00886 485918.Cpin_5856 6.8e-16 92.4 Bacteroidetes Bacteria 2CBRF@1,34BWR@2,4P5HF@976 NA|NA|NA MAG.T22.56_00887 700598.Niako_0937 0.0 1512.3 Sphingobacteriia gcvP GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3318 Bacteria 1INQX@117747,4NEDE@976,COG0403@1,COG0403@2,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MAG.T22.56_00888 925409.KI911562_gene867 6.1e-73 280.8 Bacteria soj ko:K03496 ko00000,ko03036,ko04812 Bacteria COG1192@1,COG1192@2 NA|NA|NA D plasmid maintenance MAG.T22.56_00889 1443665.JACA01000041_gene1612 5.8e-58 230.7 Aquimarina Bacteria 1IIW5@117743,2YHMK@290174,4NGQJ@976,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-monophosphate binding domain MAG.T22.56_00890 926562.Oweho_0527 7.5e-74 283.5 Cryomorphaceae 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1I0BM@117743,2PAT0@246874,4NGIK@976,COG2249@1,COG2249@2 NA|NA|NA S NADPH-quinone reductase (modulator of drug activity B) MAG.T22.56_00892 1123248.KB893359_gene2053 5.4e-125 454.1 Sphingobacteriia ko:K03924 ko00000,ko01000 Bacteria 1IPUZ@117747,4NDVZ@976,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) MAG.T22.56_00893 700598.Niako_6963 9.5e-109 399.8 Sphingobacteriia porX ko:K03413 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 1IP34@117747,4NE72@976,COG2204@1,COG2204@2 NA|NA|NA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains MAG.T22.56_00894 485918.Cpin_1874 1.4e-90 340.1 Sphingobacteriia 1.3.99.23 ko:K09516 ko00830,map00830 R07163 RC01835 ko00000,ko00001,ko01000 Bacteria 1IPAE@117747,4NG5Y@976,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase MAG.T22.56_00895 1122621.ATZA01000016_gene3796 3.3e-22 110.9 Sphingobacteriia ko:K07461 ko00000 Bacteria 1ITK9@117747,4NUYX@976,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain MAG.T22.56_00896 700598.Niako_6577 1.7e-176 625.2 Sphingobacteriia dys 2.5.1.46 ko:K00809 ko00000,ko01000 Bacteria 1IPCP@117747,4NEZ0@976,COG1899@1,COG1899@2 NA|NA|NA O Deoxyhypusine synthase MAG.T22.56_00897 485918.Cpin_6916 7.8e-196 689.9 Sphingobacteriia gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IQX9@117747,4NFXK@976,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family MAG.T22.56_00898 1270196.JCKI01000005_gene3114 3.1e-84 318.9 Sphingobacteriia recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1IP1J@117747,4NFHN@976,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP MAG.T22.56_00899 485918.Cpin_5455 1.3e-147 529.3 Sphingobacteriia pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IPU9@117747,4NF2J@976,COG1071@1,COG1071@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T22.56_00900 700598.Niako_2026 7.6e-41 174.1 Sphingobacteriia cpoB 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1IYXS@117747,4NEM2@976,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_00901 485918.Cpin_5453 6e-51 207.2 Sphingobacteriia ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 Bacteria 1ISBW@117747,4NNUC@976,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin MAG.T22.56_00902 485918.Cpin_5452 1.1e-98 366.3 Sphingobacteriia lutA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K18928 ko00000 iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338 Bacteria 1IPJX@117747,4NIMP@976,COG0247@1,COG0247@2 NA|NA|NA C Fe-S oxidoreductase MAG.T22.56_00903 925409.KI911562_gene2640 5.7e-44 183.7 Sphingobacteriia osmC ko:K04063 ko00000 Bacteria 1IT1Y@117747,4NQKB@976,COG1764@1,COG1764@2 NA|NA|NA O TIGRFAM Peroxiredoxin, osmotically inducible protein C, subgroup MAG.T22.56_00904 485918.Cpin_1533 3.3e-140 504.6 Sphingobacteriia prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 1INUM@117747,4NEVF@976,COG0462@1,COG0462@2 NA|NA|NA EF Ribose-phosphate pyrophosphokinase MAG.T22.56_00905 485918.Cpin_1534 6.8e-67 260.4 Sphingobacteriia ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 1IST6@117747,4NEN6@976,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance MAG.T22.56_00906 1313421.JHBV01000039_gene2760 2.4e-88 333.6 Bacteroidetes 1.11.1.7 ko:K19511,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 4NFV5@976,COG2931@1,COG2931@2 NA|NA|NA Q PFAM FG-GAP repeat MAG.T22.56_00907 485918.Cpin_4665 4.2e-91 341.3 Sphingobacteriia Bacteria 1INZY@117747,4NEMK@976,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.56_00908 338963.Pcar_1033 4.2e-32 144.4 Desulfuromonadales purE 5.4.99.18,6.3.4.13 ko:K01588,ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R07405 RC00090,RC00166,RC01947 ko00000,ko00001,ko00002,ko01000 Bacteria 1RCWJ@1224,2WPG2@28221,42QTK@68525,43UKG@69541,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T22.56_00909 485918.Cpin_5436 5e-134 484.2 Sphingobacteriia phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1INQV@117747,4NDYV@976,COG1702@1,COG1702@2 NA|NA|NA T Phosphate starvation-inducible protein PhoH MAG.T22.56_00912 485918.Cpin_6855 1.6e-36 160.6 Sphingobacteriia ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1ISIQ@117747,4PMPE@976,COG0683@1,COG0683@2 NA|NA|NA E leucine binding MAG.T22.56_00913 509635.N824_13440 5.1e-58 231.9 Sphingobacteriia wecA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008963,GO:0009058,GO:0009059,GO:0009103,GO:0009246,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046378,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.8.33,2.7.8.35,5.1.3.14 ko:K01791,ko:K02851 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R08856 RC00002,RC00290 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 iAF987.Gmet_1505,iECSF_1327.ECSF_3624 Bacteria 1INPS@117747,4NGKM@976,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase, family 4 MAG.T22.56_00914 743722.Sph21_1828 8.4e-71 274.2 Sphingobacteriia wecB 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IR9A@117747,4NGBD@976,COG0381@1,COG0381@2 NA|NA|NA M Belongs to the UDP-N-acetylglucosamine 2-epimerase family MAG.T22.56_00915 1267211.KI669560_gene203 4.2e-87 328.2 Sphingobacteriia argK ko:K07588 ko00000,ko01000 Bacteria 1IQ92@117747,4NE7Y@976,COG1703@1,COG1703@2 NA|NA|NA E LAO AO transport system ATPase MAG.T22.56_00916 269798.CHU_0602 1.6e-28 134.0 Cytophagia GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 ko:K02847 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 Bacteria 47R1I@768503,4NU0S@976,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase MAG.T22.56_00917 485918.Cpin_0508 2.5e-62 245.4 Sphingobacteriia lonD 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1IY3D@117747,4NEJU@976,COG2802@1,COG2802@2 NA|NA|NA S Peptidase S16 lon domain protein MAG.T22.56_00918 1267211.KI669560_gene207 1.4e-53 216.5 Sphingobacteriia coaX 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISYG@117747,4NE9E@976,COG1521@1,COG1521@2 NA|NA|NA K Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis MAG.T22.56_00919 1123248.KB893348_gene286 6e-60 238.4 Sphingobacteriia Bacteria 1IPB7@117747,4NEP1@976,COG2067@1,COG2067@2 NA|NA|NA I membrane MAG.T22.56_00920 485918.Cpin_0507 2.8e-28 132.1 Sphingobacteriia lptC ko:K09774,ko:K11719 ko00000,ko02000 1.B.42.1 Bacteria 1IU6N@117747,4NV8G@976,COG3117@1,COG3117@2 NA|NA|NA S Lipopolysaccharide-assembly, LptC-related MAG.T22.56_00921 929556.Solca_1313 1.7e-208 732.6 Sphingobacteriia dpp7 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 Bacteria 1IPZY@117747,4NEAK@976,COG3591@1,COG3591@2 NA|NA|NA E Peptidase S46 MAG.T22.56_00922 925409.KI911562_gene1148 2.9e-97 362.1 Sphingobacteriia gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1IQF4@117747,4NF4R@976,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase MAG.T22.56_00923 1123248.KB893321_gene470 1.5e-90 340.1 Sphingobacteriia ko:K02005,ko:K16922 ko00000,ko01002 Bacteria 1J0U2@117747,4PMCY@976,COG1566@1,COG1566@2 NA|NA|NA V Biotin-lipoyl like MAG.T22.56_00924 700598.Niako_7335 0.0 1100.5 Sphingobacteriia metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Bacteria 1IPA1@117747,4NECB@976,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation MAG.T22.56_00926 485918.Cpin_1641 5.3e-83 313.9 Sphingobacteriia rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1INSQ@117747,4NEMZ@976,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit MAG.T22.56_00927 1122605.KB893647_gene436 8.2e-56 223.0 Sphingobacteriia rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISSN@117747,4NNHA@976,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome MAG.T22.56_00928 485918.Cpin_1639 2.5e-54 218.0 Sphingobacteriia rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISH0@117747,4NNGZ@976,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MAG.T22.56_00929 216432.CA2559_05830 3.9e-11 72.8 Flavobacteriia rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1I6A2@117743,4NXGE@976,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family MAG.T22.56_00930 485918.Cpin_1637 1.3e-30 138.7 Sphingobacteriia infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1IT95@117747,4NS6S@976,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T22.56_00931 700598.Niako_2550 1.1e-45 189.9 Sphingobacteriia gmhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 2.7.7.71,3.1.3.15,3.1.3.82,3.1.3.83,4.2.1.19 ko:K01089,ko:K03273,ko:K15669 ko00340,ko00540,ko01100,ko01110,ko01230,map00340,map00540,map01100,map01110,map01230 M00026,M00064 R03013,R03457,R05647,R09771,R09772 RC00002,RC00017,RC00932 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IU3D@117747,4NR54@976,COG0241@1,COG0241@2 NA|NA|NA E D,D-heptose 1,7-bisphosphate phosphatase MAG.T22.56_00932 700598.Niako_2548 4.2e-69 267.7 Sphingobacteriia gmhA 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IRJQ@117747,4NJX7@976,COG0279@1,COG0279@2 NA|NA|NA G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate MAG.T22.56_00933 485918.Cpin_1529 4.2e-176 624.0 Sphingobacteriia queA 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1INNG@117747,4NF2T@976,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T22.56_00934 1358423.N180_18945 5.9e-208 730.3 Sphingobacteriia dapE 3.5.1.16,3.5.1.18 ko:K01436,ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1IQ95@117747,4NFGE@976,COG0624@1,COG0624@2 NA|NA|NA E Peptidase, family M20 M25 M40 MAG.T22.56_00935 485918.Cpin_6626 4e-82 311.2 Sphingobacteriia cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25,6.3.2.1 ko:K00800,ko:K00945,ko:K03977,ko:K13799 ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230 M00022,M00052,M00119 R00158,R00512,R01665,R02473,R03460 RC00002,RC00096,RC00141,RC00350 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1IRY5@117747,4NEMB@976,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily MAG.T22.56_00936 929713.NIASO_20365 7.7e-161 573.9 Sphingobacteriia polX ko:K02347,ko:K04477 ko00000,ko03400 Bacteria 1IPE5@117747,4NDX5@976,COG1387@1,COG1387@2,COG1796@1,COG1796@2 NA|NA|NA L DNA polymerase MAG.T22.56_00937 1121904.ARBP01000015_gene166 2e-55 222.2 Cytophagia clpP1 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 47K60@768503,4NE20@976,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T22.56_00938 153721.MYP_2663 3e-18 98.2 Cytophagia ko:K13638,ko:K19591 M00769 ko00000,ko00002,ko01504,ko03000 Bacteria 47X79@768503,4NW77@976,COG0789@1,COG0789@2 NA|NA|NA K MerR, DNA binding MAG.T22.56_00939 1122176.KB903536_gene1856 5.9e-48 197.6 Bacteroidetes 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 4NNNJ@976,COG4902@1,COG4902@2 NA|NA|NA S Uncharacterized protein domain (DUF2202) MAG.T22.56_00940 925409.KI911562_gene2147 1.6e-176 625.5 Sphingobacteriia atoB 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_2215 Bacteria 1IP5F@117747,4NE3Q@976,COG0183@1,COG0183@2 NA|NA|NA I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation MAG.T22.56_00941 1216967.L100_01020 1.3e-58 233.4 Elizabethkingia Bacteria 1I2D3@117743,34PQ9@308865,4NNX7@976,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain MAG.T22.56_00942 395493.BegalDRAFT_1071 6.3e-57 228.8 Gammaproteobacteria ycbB ko:K21470 ko00000,ko01002,ko01011 Bacteria 1MV14@1224,1RQR7@1236,COG2989@1,COG2989@2 NA|NA|NA M protein conserved in bacteria MAG.T22.56_00943 700598.Niako_6484 6.2e-36 156.8 Sphingobacteriia ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 ko:K00567,ko:K07443 ko00000,ko01000,ko03400 Bacteria 1IT8P@117747,4NQ34@976,COG3695@1,COG3695@2 NA|NA|NA L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain MAG.T22.56_00944 700598.Niako_6485 8.2e-12 75.9 Sphingobacteriia Bacteria 1IUKX@117747,2E5CT@1,3304V@2,4NUT8@976 NA|NA|NA MAG.T22.56_00945 485918.Cpin_1011 4e-69 268.1 Sphingobacteriia trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1ISBF@117747,4NG4V@976,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA MAG.T22.56_00946 762903.Pedsa_1587 3.8e-100 371.7 Sphingobacteriia Bacteria 1IR13@117747,2CB8G@1,2Z88H@2,4NF68@976 NA|NA|NA S Putative beta-barrel porin-2, OmpL-like. bbp2 MAG.T22.56_00947 700598.Niako_4436 1.4e-55 222.6 Sphingobacteriia spoU 2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1IS2Z@117747,4NM8C@976,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family MAG.T22.56_00948 1288963.ADIS_3596 6.2e-24 116.7 Cytophagia clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 47R8K@768503,4NS8R@976,COG2127@1,COG2127@2 NA|NA|NA S PFAM ATP-dependent Clp protease adaptor protein ClpS MAG.T22.56_00950 929556.Solca_1443 1.1e-210 740.0 Sphingobacteriia dpp 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 1IQ4I@117747,4NETS@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU peptidase MAG.T22.56_00951 700598.Niako_1186 4.8e-46 191.8 Sphingobacteriia rbn ko:K03466,ko:K07058 ko00000,ko03036 3.A.12 Bacteria 1IPC8@117747,4NFY6@976,COG1295@1,COG1295@2 NA|NA|NA S ribonuclease BN MAG.T22.56_00952 1356852.N008_04075 1.2e-74 287.3 Cytophagia peaA 1.4.9.1 ko:K08685 ko00680,ko01120,map00680,map01120 R00606 RC00189 ko00000,ko00001,ko01000 Bacteria 47M30@768503,4NEEJ@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_00953 700598.Niako_1185 6.2e-39 167.5 Bacteroidetes Bacteria 4NMEK@976,COG1225@1,COG1225@2 NA|NA|NA O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.56_00954 1123278.KB893558_gene3276 1.9e-68 266.5 Cytophagia Bacteria 28HNS@1,2Z7WY@2,47MGX@768503,4NDYC@976 NA|NA|NA S Domain of unknown function (DUF4856) MAG.T22.56_00955 1121373.KB903628_gene1409 8.3e-74 284.3 Cytophagia ko:K07338 ko00000 Bacteria 47NBA@768503,4NFAT@976,COG3489@1,COG3489@2 NA|NA|NA S Imelysin MAG.T22.56_00956 1123278.KB893558_gene3274 2.6e-149 535.4 Cytophagia Bacteria 47KZT@768503,4NE9C@976,COG3250@1,COG3250@2 NA|NA|NA G Horizontally Transferred TransMembrane Domain MAG.T22.56_00957 504472.Slin_4532 1.1e-213 750.0 Cytophagia fecA ko:K16091 ko00000,ko02000 1.B.14.1.14 Bacteria 47KFP@768503,4NH5V@976,COG4772@1,COG4772@2 NA|NA|NA P PFAM TonB-dependent Receptor MAG.T22.56_00959 700598.Niako_5173 3.1e-112 411.8 Sphingobacteriia 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 Bacteria 1IZDH@117747,4NNB2@976,COG3239@1,COG3239@2 NA|NA|NA I PFAM Fatty acid desaturase MAG.T22.56_00960 485918.Cpin_2595 7.7e-70 270.0 Sphingobacteriia waaM 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IRHE@117747,4NGQU@976,COG1560@1,COG1560@2 NA|NA|NA M PFAM Bacterial lipid A biosynthesis acyltransferase MAG.T22.56_00961 1121896.JMLU01000010_gene1401 2.7e-160 572.0 Flavobacterium hutH 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 1HX2V@117743,2NSUV@237,4NE0D@976,COG2986@1,COG2986@2 NA|NA|NA E Histidine ammonia-lyase MAG.T22.56_00962 1121373.KB903662_gene12 7.7e-99 367.1 Cytophagia Bacteria 47MB5@768503,4NEZP@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T22.56_00963 700598.Niako_6528 4e-152 545.4 Sphingobacteriia ko:K07001 ko00000 Bacteria 1IWMA@117747,4NF97@976,COG1752@1,COG1752@2 NA|NA|NA S Esterase of the alpha-beta hydrolase superfamily MAG.T22.56_00964 1123248.KB893322_gene622 5.1e-105 387.9 Sphingobacteriia ctaA ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 Bacteria 1IQDH@117747,4NIT1@976,COG1612@1,COG1612@2 NA|NA|NA O protein required for cytochrome oxidase assembly MAG.T22.56_00965 485918.Cpin_0938 4.6e-33 147.1 Sphingobacteriia hupA ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1ISXQ@117747,4NT0D@976,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family MAG.T22.56_00966 1267211.KI669560_gene768 7.2e-33 147.9 Sphingobacteriia Bacteria 1IQYF@117747,4NEV2@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_00968 700598.Niako_5795 9.9e-206 723.0 Sphingobacteriia rng 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 1IQ78@117747,4NED1@976,COG1530@1,COG1530@2 NA|NA|NA J ribonuclease, Rne Rng family MAG.T22.56_00969 755732.Fluta_2202 2.4e-14 86.3 Cryomorphaceae Bacteria 1IHVQ@117743,2A33Q@1,2PBYM@246874,30RIR@2,4PH5X@976 NA|NA|NA MAG.T22.56_00970 929562.Emtol_3051 8e-45 187.2 Cytophagia Bacteria 47QIT@768503,4NQVA@976,COG2197@1,COG2197@2 NA|NA|NA K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.56_00971 485918.Cpin_0409 0.0 1553.5 Sphingobacteriia mfd 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 GT51 Bacteria 1IPC5@117747,4NEPA@976,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site MAG.T22.56_00972 448385.sce1514 6.6e-35 154.1 Myxococcales Bacteria 1MXQ8@1224,2X6JH@28221,2Z3BE@29,43B5X@68525,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase MAG.T22.56_00974 1122176.KB903557_gene4041 1.9e-110 405.6 Sphingobacteriia paaH 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 1IURZ@117747,4NF2W@976,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MAG.T22.56_00975 700598.Niako_6017 1.1e-44 186.0 Sphingobacteriia recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1INZ4@117747,4NEWI@976,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO MAG.T22.56_00976 485918.Cpin_4694 9.7e-77 293.5 Sphingobacteriia dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 1IP6C@117747,4NF26@976,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan MAG.T22.56_00977 1408433.JHXV01000005_gene2237 1.5e-41 177.6 Cryomorphaceae Bacteria 1I8VS@117743,2ENP2@1,2PB29@246874,33GAE@2,4NZIT@976 NA|NA|NA MAG.T22.56_00978 485918.Cpin_6224 4e-39 168.3 Sphingobacteriia Bacteria 1ITPJ@117747,4NM5H@976,COG0224@1,COG0224@2 NA|NA|NA C WbqC-like protein family MAG.T22.56_00979 1122605.KB893627_gene2880 1.3e-91 342.8 Sphingobacteriia ppm1 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 1IRP1@117747,4NEHI@976,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 MAG.T22.56_00980 485918.Cpin_2340 5.3e-83 314.3 Sphingobacteriia dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1IPA8@117747,4NE82@976,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III MAG.T22.56_00981 700598.Niako_4423 5.3e-139 501.1 Sphingobacteriia murC 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1IPU5@117747,4NF99@976,COG0773@1,COG0773@2 NA|NA|NA M Mur ligase middle domain MAG.T22.56_00985 485918.Cpin_2035 2.9e-18 99.0 Bacteria Bacteria COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.56_00986 485918.Cpin_4721 4.1e-122 445.3 Sphingobacteriia bshC ko:K22136 ko00000 Bacteria 1IP68@117747,4NGCF@976,COG4365@1,COG4365@2 NA|NA|NA S Belongs to the BshC family MAG.T22.56_00987 926569.ANT_02430 7.9e-30 137.5 Chloroflexi Bacteria 2A1JS@1,2G9H1@200795,30PTP@2 NA|NA|NA MAG.T22.56_00988 1121101.HMPREF1532_01911 2.7e-15 89.7 Bacteria ko:K20274 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria COG2911@1,COG2911@2 NA|NA|NA S protein secretion MAG.T22.56_00990 485918.Cpin_3106 2.7e-48 199.1 Bacteroidetes Bacteria 2BH0I@1,32B0P@2,4P6EF@976 NA|NA|NA S Protein of unknown function MAG.T22.56_00992 1123248.KB893337_gene2491 5.1e-208 730.3 Sphingobacteriia Bacteria 1IWQT@117747,4NZSZ@976,COG0535@1,COG0535@2 NA|NA|NA S Elongator protein 3, MiaB family, Radical SAM MAG.T22.56_00994 485918.Cpin_5464 1.8e-100 372.9 Sphingobacteriia tpiA 5.3.1.1 ko:K01803,ko:K15977 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IPIJ@117747,4NGNF@976,COG1225@1,COG1225@2,COG2259@1,COG2259@2 NA|NA|NA O DoxX family MAG.T22.56_00995 929713.NIASO_04665 5.5e-55 220.7 Sphingobacteriia Bacteria 1IRWB@117747,28HFG@1,2Z7RJ@2,4NFNY@976 NA|NA|NA S Domain of Unknown Function (DUF1599) MAG.T22.56_00996 1123248.KB893325_gene1164 2.7e-88 332.0 Sphingobacteriia folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPC6@117747,4NEYJ@976,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives MAG.T22.56_00997 1122605.KB893648_gene3699 3.3e-142 511.5 Sphingobacteriia Bacteria 1INYT@117747,4NFWE@976,COG0454@1,COG0456@2 NA|NA|NA K Psort location Cytoplasmic, score 8.96 MAG.T22.56_00998 760192.Halhy_1230 1e-101 377.9 Sphingobacteriia xynX5 Bacteria 1IRAV@117747,4NER3@976,COG2304@1,COG2304@2 NA|NA|NA S oxidoreductase activity MAG.T22.56_00999 1123248.KB893359_gene2116 3e-137 495.4 Sphingobacteriia cho GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 ko:K02342,ko:K03703,ko:K03763,ko:K05984 ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1IQ4K@117747,4NEQX@976,COG0322@1,COG0322@2,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III, epsilon subunit MAG.T22.56_01000 700598.Niako_7245 6.4e-71 274.2 Sphingobacteriia dsb 5.3.4.1 ko:K01829 ko00000,ko01000 Bacteria 1IQYQ@117747,4NJ3N@976,COG2761@1,COG2761@2 NA|NA|NA Q dithiol-disulfide isomerase involved in polyketide biosynthesis MAG.T22.56_01001 1123278.KB893428_gene99 9.8e-07 62.0 Cytophagia Bacteria 47KW1@768503,4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T22.56_01002 761193.Runsl_5101 1.3e-63 250.0 Cytophagia ko:K07017 ko00000 Bacteria 47N0B@768503,4NGAG@976,COG2819@1,COG2819@2 NA|NA|NA S Putative esterase MAG.T22.56_01005 925409.KI911562_gene1555 1.9e-69 269.6 Sphingobacteriia Bacteria 1IS63@117747,4NEHG@976,COG2374@1,COG2374@2 NA|NA|NA S Endonuclease exonuclease phosphatase family MAG.T22.56_01007 925409.KI911562_gene2239 6.4e-118 430.6 Sphingobacteriia pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Bacteria 1IPUF@117747,4NF8F@976,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T22.56_01008 1121930.AQXG01000004_gene2843 4.7e-07 62.0 Sphingobacteriia xynX5 3.2.1.8 ko:K01181 ko00000,ko01000 Bacteria 1IY1S@117747,4PPNB@976,COG0737@1,COG0737@2,COG2356@1,COG2356@2 NA|NA|NA F Belongs to the 5'-nucleotidase family MAG.T22.56_01009 925409.KI911562_gene1308 4e-45 187.2 Sphingobacteriia ypjD 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 1ISAQ@117747,4NQ3H@976,COG1694@1,COG1694@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase MAG.T22.56_01010 760192.Halhy_3606 1.7e-123 449.1 Sphingobacteriia moxR ko:K03924 ko00000,ko01000 Bacteria 1INQ9@117747,4NDVZ@976,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T22.56_01011 755732.Fluta_1196 4.7e-18 97.8 Cryomorphaceae Bacteria 1IB9P@117743,2PBY4@246874,4NUTF@976,COG2030@1,COG2030@2 NA|NA|NA I Protein of unknown function (DUF1569) MAG.T22.56_01012 485918.Cpin_6194 6.5e-122 444.1 Sphingobacteriia nhaA ko:K03313 ko00000,ko02000 2.A.33.1 iIT341.HP1552 Bacteria 1INUT@117747,4NFC4@976,COG3004@1,COG3004@2 NA|NA|NA P ) H( ) antiporter that extrudes sodium in exchange for external protons MAG.T22.56_01013 1313421.JHBV01000039_gene2646 8.9e-32 143.7 Sphingobacteriia ushA 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 1ITBW@117747,4NR6D@976,COG0737@1,COG0737@2 NA|NA|NA F 5'-nucleotidase MAG.T22.56_01014 1150600.ADIARSV_4269 9.1e-98 363.6 Sphingobacteriia 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1IQB8@117747,4NESM@976,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family MAG.T22.56_01015 485918.Cpin_0001 8.7e-204 716.5 Sphingobacteriia dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1INXF@117747,4NE6Q@976,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T22.56_01016 1042376.AFPK01000034_gene1249 6.4e-14 84.3 Flavobacteriia Bacteria 1I75I@117743,2DNTN@1,32Z32@2,4NVQM@976 NA|NA|NA MAG.T22.56_01017 313606.M23134_01410 6.3e-29 134.0 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47PTY@768503,4NQCH@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.56_01021 700598.Niako_2034 2.4e-213 748.4 Sphingobacteriia rluA 5.4.99.28,5.4.99.29 ko:K06177 ko00000,ko01000,ko03009,ko03016 Bacteria 1IQQK@117747,4NE9B@976,COG0564@1,COG0564@2 NA|NA|NA J Pseudouridine synthase MAG.T22.56_01022 1121875.KB907547_gene3503 1.2e-42 179.1 Flavobacteriia ble Bacteria 1I2S1@117743,4NQRN@976,COG0346@1,COG0346@2 NA|NA|NA E bleomycin resistance protein MAG.T22.56_01023 1121287.AUMU01000001_gene1686 1e-37 162.9 Flavobacteriia Bacteria 1IJ1S@117743,4NX9B@976,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix MAG.T22.56_01024 1317122.ATO12_16510 5.1e-18 97.8 Aquimarina Bacteria 1I3CW@117743,2YI08@290174,4NRXW@976,COG0457@1,COG0457@2 NA|NA|NA S COG0457 FOG TPR repeat MAG.T22.56_01025 755732.Fluta_0090 5.6e-47 194.5 Cryomorphaceae Bacteria 1I314@117743,2PB9G@246874,4NU7A@976,COG4743@1,COG4743@2 NA|NA|NA S Protein of unknown function (DUF1616) MAG.T22.56_01026 313606.M23134_04780 4.4e-34 150.6 Cytophagia Bacteria 47QGA@768503,4NQBA@976,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T22.56_01027 1317122.ATO12_24670 2.2e-23 114.8 Aquimarina ko:K15977 ko00000 Bacteria 1I0YP@117743,2YJR6@290174,4NK73@976,COG2259@1,COG2259@2 NA|NA|NA S Doxx family MAG.T22.56_01028 485918.Cpin_5890 3.5e-51 208.0 Sphingobacteriia Bacteria 1ITP3@117747,28NRS@1,2ZBQZ@2,4NMM5@976 NA|NA|NA MAG.T22.56_01030 485918.Cpin_5887 6.2e-121 440.3 Sphingobacteriia Bacteria 1IP0Z@117747,4NDZS@976,COG0247@1,COG0247@2 NA|NA|NA C Fe-S oxidoreductase MAG.T22.56_01031 485918.Cpin_5886 2.1e-172 612.1 Sphingobacteriia Bacteria 1IQ7C@117747,4NF3K@976,COG1150@1,COG1150@2 NA|NA|NA C Fe-S oxidoreductase MAG.T22.56_01032 1123248.KB893314_gene3555 1.2e-43 183.7 Sphingobacteriia Bacteria 1IRUJ@117747,28P29@1,2ZBYD@2,4NMK6@976 NA|NA|NA MAG.T22.56_01034 305900.GV64_05840 7.7e-23 114.8 Proteobacteria ko:K07474 ko00000 Bacteria 1QYM2@1224,COG1674@1,COG1674@2 NA|NA|NA D ftsk spoiiie MAG.T22.56_01035 1454007.JAUG01000064_gene294 5.2e-61 240.7 Bacteria Bacteria 28WU8@1,2ZITQ@2 NA|NA|NA MAG.T22.56_01036 215803.DB30_8826 1.8e-77 295.4 Proteobacteria Bacteria 1RA0C@1224,28H95@1,2Z7KY@2 NA|NA|NA S Protein of unknown function (DUF4256) MAG.T22.56_01037 700598.Niako_5688 7.5e-86 323.6 Sphingobacteriia 2.3.1.178,2.3.1.57,2.3.1.82 ko:K00657,ko:K06718,ko:K18816 ko00260,ko00330,ko01100,ko01120,ko04216,map00260,map00330,map01100,map01120,map04216 M00033,M00135 R01154,R06978 RC00004,RC00096 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1IR6P@117747,4PKMC@976,COG1670@1,COG1670@2 NA|NA|NA J acetyltransferase MAG.T22.56_01038 929556.Solca_3551 4.2e-164 584.3 Sphingobacteriia argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1INXV@117747,4NE3R@976,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily MAG.T22.56_01039 925409.KI911562_gene428 5.6e-122 444.1 Sphingobacteriia argC 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPHE@117747,4NEQR@976,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde MAG.T22.56_01040 700598.Niako_5691 1.7e-162 578.9 Sphingobacteriia 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1IQUC@117747,4NE0Z@976,COG4992@1,COG4992@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T22.56_01041 700598.Niako_5692 2.2e-131 475.3 Sphingobacteriia argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.3,2.1.3.9 ko:K00611,ko:K09065,ko:K13043 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245,R08937 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ2H@117747,4NEYX@976,COG0078@1,COG0078@2 NA|NA|NA E Belongs to the ATCase OTCase family MAG.T22.56_01042 391596.PBAL39_12072 2.9e-73 282.0 Sphingobacteriia argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 Bacteria 1IPBE@117747,4NDY8@976,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily MAG.T22.56_01043 391596.PBAL39_12082 2.5e-123 448.7 Sphingobacteriia argE 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQBT@117747,4NE2G@976,COG0624@1,COG0624@2 NA|NA|NA E PFAM Peptidase family M20 M25 M40 MAG.T22.56_01046 269798.CHU_3522 2e-98 366.3 Cytophagia Bacteria 47NWX@768503,4NGTK@976,COG2755@1,COG2755@2 NA|NA|NA E GDSL family lipolytic protein MAG.T22.56_01047 1121373.KB903621_gene1880 2.4e-98 365.9 Cytophagia fadL ko:K06076 ko00000,ko02000 1.B.9 Bacteria 47NDV@768503,4NFFF@976,COG2067@1,COG2067@2 NA|NA|NA I Outer membrane protein transport protein (OMPP1/FadL/TodX) MAG.T22.56_01048 1313421.JHBV01000024_gene4965 1.4e-50 206.5 Sphingobacteriia comF Bacteria 1IRYV@117747,4NNI1@976,COG1040@1,COG1040@2 NA|NA|NA S PFAM Phosphoribosyl transferase domain MAG.T22.56_01049 485918.Cpin_0878 1.1e-179 636.3 Sphingobacteriia radA ko:K04485 ko00000,ko03400 Bacteria 1IQC6@117747,4NEYA@976,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function MAG.T22.56_01050 485918.Cpin_0534 1.5e-223 782.3 Sphingobacteriia pepF ko:K08602 ko00000,ko01000,ko01002 Bacteria 1INVA@117747,4NFYH@976,COG1164@1,COG1164@2 NA|NA|NA E Oligoendopeptidase F MAG.T22.56_01051 700598.Niako_6681 4.4e-68 264.6 Sphingobacteriia hddC 2.7.7.13,2.7.7.24 ko:K00966,ko:K00973 ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130 M00114,M00361,M00362,M00793 R00885,R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1IXAV@117747,4NMJ5@976,COG1208@1,COG1208@2 NA|NA|NA JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) MAG.T22.56_01052 1267211.KI669560_gene745 3.1e-141 508.1 Sphingobacteriia adoK GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2683 Bacteria 1INMS@117747,4NFJ9@976,COG0524@1,COG0524@2 NA|NA|NA G PFAM pfkB family carbohydrate kinase MAG.T22.56_01053 485918.Cpin_6989 2.4e-205 721.8 Sphingobacteriia recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1IQ3R@117747,4NDW1@976,COG0608@1,COG0608@2 NA|NA|NA L TIGRFAM single-stranded-DNA-specific exonuclease RecJ MAG.T22.56_01054 926549.KI421517_gene809 2.3e-126 459.1 Cytophagia kmo GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 Bacteria 47KM9@768503,4NGIU@976,COG0654@1,COG0654@2 NA|NA|NA H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid MAG.T22.56_01055 485918.Cpin_6436 1.1e-116 426.8 Sphingobacteriia lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1IRAK@117747,4NFTP@976,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family MAG.T22.56_01056 1408433.JHXV01000006_gene2623 6.9e-80 304.3 Cryomorphaceae pgi 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1I8JM@117743,2PANV@246874,4NIX0@976,COG2222@1,COG2222@2 NA|NA|NA G PFAM Bacterial phospho-glucose isomerase C-terminal region MAG.T22.56_01057 984262.SGRA_3385 1.8e-22 112.1 Sphingobacteriia yraN ko:K07460 ko00000 Bacteria 1ITWJ@117747,4NS7E@976,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family MAG.T22.56_01058 760192.Halhy_1966 3.3e-33 149.4 Sphingobacteriia Bacteria 1ISNS@117747,4NFI8@976,COG1215@1,COG1215@2 NA|NA|NA M Pfam:DUF2029 MAG.T22.56_01059 435591.BDI_2812 3.9e-43 181.8 Porphyromonadaceae Bacteria 230NM@171551,2FQJ6@200643,4NQWJ@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.56_01060 1123277.KB893188_gene5299 1.9e-64 252.7 Cytophagia Bacteria 47P11@768503,4NHXH@976,COG0726@1,COG0726@2 NA|NA|NA G Domain of unknown function (DUF3473) MAG.T22.56_01062 1034807.FBFL15_2376 5.9e-95 354.4 Flavobacterium luxE 6.2.1.19 ko:K06046 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Bacteria 1HX4F@117743,2NSIU@237,4PKAN@976,COG1541@1,COG1541@2 NA|NA|NA H acyl transferase MAG.T22.56_01064 1408473.JHXO01000001_gene1945 1.3e-127 463.0 Bacteroidia yghO Bacteria 2FNG4@200643,4NFWE@976,COG0454@1,COG0456@2 NA|NA|NA K Psort location Cytoplasmic, score 8.96 MAG.T22.56_01065 313606.M23134_02889 2.1e-168 598.6 Cytophagia hmgA 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 Bacteria 47JCV@768503,4NEYZ@976,COG3508@1,COG3508@2 NA|NA|NA Q Homogentisate 12-dioxygenase MAG.T22.56_01066 1313421.JHBV01000043_gene3072 2.4e-180 638.3 Sphingobacteriia hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IPBI@117747,4NFI7@976,COG3185@1,COG3185@2 NA|NA|NA E 4-hydroxyphenylpyruvate dioxygenase MAG.T22.56_01067 565045.NOR51B_1998 2.4e-133 481.9 unclassified Gammaproteobacteria paaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko01000 iEC55989_1330.EC55989_1524,iECO111_1330.ECO111_1782,iECO26_1355.ECO26_1992,iEcE24377_1341.EcE24377A_1573 Bacteria 1J7JU@118884,1MVQ7@1224,1RNRN@1236,COG3396@1,COG3396@2 NA|NA|NA S Phenylacetic acid catabolic protein MAG.T22.56_01068 479433.Caci_1745 1.9e-25 121.7 Actinobacteria paaB ko:K02610 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 2IKMJ@201174,COG3460@1,COG3460@2 NA|NA|NA Q Phenylacetate-CoA oxygenase MAG.T22.56_01069 1411123.JQNH01000001_gene1832 4.5e-79 301.2 Alphaproteobacteria paaC 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko01000 Bacteria 1MVYQ@1224,2TRYF@28211,COG3396@1,COG3396@2 NA|NA|NA S phenylacetic acid degradation protein MAG.T22.56_01070 709797.CSIRO_3114 2e-43 182.2 Bradyrhizobiaceae paaD ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1RF3S@1224,2TRQW@28211,3JSNZ@41294,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein MAG.T22.56_01071 1121286.AUMT01000003_gene2098 6.5e-10 70.5 Chryseobacterium Bacteria 1IJ6S@117743,3ZURP@59732,4NDZJ@976,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase SAM-like domain MAG.T22.56_01072 1443665.JACA01000019_gene4860 6.4e-22 112.1 Aquimarina ko:K04763 ko00000,ko03036 Bacteria 1HZR0@117743,2YKD4@290174,4NI9Q@976,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase SAM-like domain MAG.T22.56_01073 1205908.AKXW01000017_gene2648 6e-09 68.2 Gammaproteobacteria Bacteria 1NRBC@1224,1RY6F@1236,COG1479@1,COG1479@2 NA|NA|NA S Protein of unknown function (DUF1524) MAG.T22.56_01074 700598.Niako_2020 3.5e-51 207.6 Sphingobacteriia dppB ko:K02033,ko:K13890 ko02010,ko02024,map02010,map02024 M00239,M00348 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 Bacteria 1IRI6@117747,4NGIJ@976,COG0601@1,COG0601@2 NA|NA|NA P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components MAG.T22.56_01076 468059.AUHA01000002_gene20 5.6e-164 583.9 Sphingobacteriia Bacteria 1INUQ@117747,4NG5Z@976,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T22.56_01077 1267211.KI669560_gene2848 1.2e-56 226.5 Sphingobacteriia ko:K07220 ko00000 Bacteria 1INNB@117747,4NI25@976,COG1392@1,COG1392@2 NA|NA|NA P COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) MAG.T22.56_01078 1122605.KB893628_gene4483 2.2e-102 379.8 Sphingobacteriia pit ko:K03306 ko00000 2.A.20 Bacteria 1IPR3@117747,4NE7J@976,COG0306@1,COG0306@2 NA|NA|NA P phosphate transporter MAG.T22.56_01079 485918.Cpin_0596 0.0 1305.8 Sphingobacteriia helZ 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1IPUE@117747,4NG6P@976,COG0553@1,COG0553@2,COG4715@1,COG4715@2 NA|NA|NA L PFAM Helicase conserved C-terminal domain MAG.T22.56_01080 760192.Halhy_0214 3.4e-127 463.4 Bacteroidetes 3.2.1.4,5.2.1.8 ko:K01179,ko:K03768,ko:K08738 ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R06200,R10151,R11307,R11308 RC03151,RC03152 ko00000,ko00001,ko00002,ko01000,ko03110 3.D.4.6 GH5,GH9 Bacteria 4PN79@976,COG3291@1,COG3291@2,COG3386@1,COG3386@2 NA|NA|NA G C-terminal domain of CHU protein family MAG.T22.56_01081 545694.TREPR_0011 3.4e-62 245.0 Bacteria ko:K05303 ko00000,ko01000 Bacteria COG4122@1,COG4122@2 NA|NA|NA E O-methyltransferase activity MAG.T22.56_01082 1123248.KB893322_gene570 3.7e-92 345.5 Sphingobacteriia surA 5.2.1.8 ko:K03771 ko00000,ko01000,ko03110 Bacteria 1IQB4@117747,4NEW0@976,COG0760@1,COG0760@2 NA|NA|NA O peptidylprolyl isomerase MAG.T22.56_01083 485918.Cpin_1137 3.2e-24 118.6 Bacteroidetes Bacteria 4NME3@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_01084 761193.Runsl_4000 4.6e-230 804.7 Cytophagia Bacteria 47Y2Y@768503,4PKFW@976,COG4206@1,COG4206@2 NA|NA|NA H Outer membrane protein beta-barrel family MAG.T22.56_01085 261292.Nit79A3_2578 3e-43 183.3 Nitrosomonadales speE 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 1N1PJ@1224,2W9WV@28216,373PI@32003,COG0421@1,COG0421@2 NA|NA|NA E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine MAG.T22.56_01086 1345697.M493_10890 1.3e-28 132.5 Geobacillus Bacteria 1V57E@1239,1WGGI@129337,4HI64@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.56_01087 236814.IX39_04580 1.3e-29 136.3 Flavobacteriia Bacteria 1I2KM@117743,2E30A@1,32Y0V@2,4NPVG@976 NA|NA|NA MAG.T22.56_01088 485918.Cpin_0397 2e-57 229.9 Sphingobacteriia dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 1IS92@117747,4NNID@976,COG1734@1,COG1734@2 NA|NA|NA T Molecular chaperone DnaK MAG.T22.56_01089 925409.KI911562_gene1439 0.0 1666.7 Sphingobacteriia ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1IPPT@117747,4NEYT@976,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) MAG.T22.56_01091 153721.MYP_1501 7.3e-23 112.5 Cytophagia Bacteria 47QIY@768503,4NQ4W@976,COG4898@1,COG4898@2 NA|NA|NA S protein conserved in bacteria MAG.T22.56_01092 1121896.JMLU01000016_gene1701 1.7e-83 315.8 Flavobacterium Bacteria 1HZ1U@117743,2NUSH@237,4NE6W@976,COG1814@1,COG1814@2 NA|NA|NA S VIT family MAG.T22.56_01093 762903.Pedsa_1463 6.3e-16 90.5 Bacteroidetes Bacteria 2DF5F@1,32U4P@2,4NTSC@976 NA|NA|NA MAG.T22.56_01094 1297569.MESS2_510038 1.8e-26 125.6 Proteobacteria Bacteria 1NDRQ@1224,2AJZ7@1,31ANF@2 NA|NA|NA MAG.T22.56_01096 700598.Niako_6991 2.4e-09 69.7 Sphingobacteriia sixA-2 ko:K08296 ko00000,ko01000 Bacteria 1J02E@117747,4P7SQ@976,COG5607@1,COG5607@2 NA|NA|NA S PFAM CHAD domain MAG.T22.56_01097 926569.ANT_26140 1.2e-62 247.7 Bacteria Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T22.56_01098 926569.ANT_26150 1e-64 254.2 Chloroflexi ko:K16703 ko00000,ko01000,ko01003 GT4 Bacteria 2G9B8@200795,COG0438@1,COG0438@2 NA|NA|NA M PFAM glycosyl transferase group 1 MAG.T22.56_01099 1123035.ARLA01000022_gene680 6.3e-52 212.2 Psychroflexus 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1IA9Q@117743,4C48I@83612,4NKKP@976,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T22.56_01100 1121889.AUDM01000008_gene813 1.9e-41 176.8 Flavobacteriia csaB Bacteria 1HXIZ@117743,4NKJN@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T22.56_01101 1296416.JACB01000017_gene5217 1.7e-51 210.3 Bacteroidetes ko:K09691 ko02010,map02010 M00250 ko00000,ko00001,ko00002,ko02000 3.A.1.103 Bacteria 4P88Y@976,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_01102 1121889.AUDM01000008_gene810 1.8e-52 213.8 Flavobacterium Bacteria 1HZ63@117743,2NVNY@237,4NFKD@976,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T22.56_01103 411479.BACUNI_04312 6e-68 263.8 Bacteroidaceae wbpD 2.3.1.201 ko:K13018 ko00520,map00520 R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 Bacteria 2FP5Y@200643,4AQ60@815,4NENC@976,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide repeat protein MAG.T22.56_01104 1034807.FBFL15_0740 3.3e-175 621.3 Flavobacterium wbpO ko:K02474 ko00520,map00520 R06894 RC00291 ko00000,ko00001,ko01000,ko01005 Bacteria 1HWYT@117743,2NTDW@237,4NDTW@976,COG0677@1,COG0677@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T22.56_01105 485918.Cpin_4764 5.7e-181 641.3 Sphingobacteriia wzc GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 ko:K16692 ko00000,ko01000,ko01001 Bacteria 1IPJ8@117747,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM PFAM lipopolysaccharide biosynthesis MAG.T22.56_01106 1121456.ATVA01000017_gene120 1.4e-26 127.5 Desulfovibrionales ko:K09691 ko02010,map02010 M00250 ko00000,ko00001,ko00002,ko02000 3.A.1.103 Bacteria 1Q12Q@1224,2MFNK@213115,2X1TJ@28221,4372A@68525,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_01107 443143.GM18_1442 4.3e-61 241.1 Desulfuromonadales hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4X@1224,2WMNR@28221,42QX8@68525,43TF4@69541,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR MAG.T22.56_01108 385682.AFSL01000064_gene1724 3e-11 75.1 Marinilabiliaceae ko:K03646,ko:K03832 ko00000,ko02000 2.C.1.1,2.C.1.2 Bacteria 2FM9A@200643,3XJ6S@558415,4NG4I@976,COG0810@1,COG0810@2 NA|NA|NA M TonB family domain protein MAG.T22.56_01109 929556.Solca_0669 2e-122 446.0 Sphingobacteriia folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166,iSB619.SA_RS08370 Bacteria 1IQU2@117747,4NES8@976,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family MAG.T22.56_01110 1434325.AZQN01000003_gene2583 3.7e-159 568.2 Cytophagia wcaJ GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 ko:K05946,ko:K21303 ko05111,map05111 ko00000,ko00001,ko01000,ko01003,ko01005 GT26 Bacteria 47XQ7@768503,4NFIA@976,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase MAG.T22.56_01111 760192.Halhy_1315 3.7e-29 135.6 Bacteroidetes Bacteria 2FG80@1,3484C@2,4P5E2@976 NA|NA|NA MAG.T22.56_01112 1267211.KI669560_gene2326 5.2e-112 411.0 Sphingobacteriia gnnA ko:K09949 ko00000 iAF987.Gmet_2352 Bacteria 1IX1W@117747,4NEC6@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.56_01113 926562.Oweho_3332 3e-66 258.5 Cryomorphaceae radC ko:K03630 ko00000 Bacteria 1HXJ3@117743,2PAQH@246874,4NFBF@976,COG2003@1,COG2003@2 NA|NA|NA L RadC-like JAB domain MAG.T22.56_01114 1107311.Q767_01615 1.2e-90 340.9 Flavobacterium ko:K12287,ko:K14274 ko00040,map00040 R02427 RC00713 ko00000,ko00001,ko01000,ko02044 Bacteria 1IKME@117743,2NXAD@237,4NNUN@976,COG1520@1,COG1520@2,COG3291@1,COG3291@2,COG3386@1,COG3386@2,COG5306@1,COG5306@2 NA|NA|NA G PFAM SMP-30 Gluconolaconase MAG.T22.56_01116 485918.Cpin_3078 2.9e-207 728.8 Sphingobacteriia ccmF ko:K02198 ko00000,ko02000 9.B.14.1 Bacteria 1IQAC@117747,4NGXI@976,COG1138@1,COG1138@2 NA|NA|NA O PFAM Cytochrome c assembly protein MAG.T22.56_01117 485918.Cpin_3077 1.2e-35 156.0 Sphingobacteriia ccmE ko:K02197 ko00000 Bacteria 1IT63@117747,4NN85@976,COG2332@1,COG2332@2 NA|NA|NA O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH MAG.T22.56_01118 485918.Cpin_3076 2.9e-129 468.4 Sphingobacteriia speB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 1IV0I@117747,4NE01@976,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T22.56_01119 1121899.Q764_06910 2.2e-26 125.2 Flavobacterium ko:K07090 ko00000 Bacteria 1I2UM@117743,2NWMD@237,4NTZ8@976,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T22.56_01120 700598.Niako_6418 1.8e-225 788.5 Sphingobacteriia asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iSDY_1059.SDY_2327 Bacteria 1IPJK@117747,4NDY4@976,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase MAG.T22.56_01121 761193.Runsl_0377 3e-24 118.2 Cytophagia ko:K16089 ko00000,ko02000 1.B.14.1,1.B.14.10 Bacteria 47M7Q@768503,4NDWS@976,COG0810@1,COG0810@2,COG1629@1,COG4219@1,COG4219@2,COG4771@2 NA|NA|NA KMT PFAM BlaR1 peptidase M56 MAG.T22.56_01122 1123037.AUDE01000008_gene723 2.6e-40 172.2 Flavobacteriia MA20_22045 ko:K06953 ko00000 Bacteria 1I1BT@117743,4NMCE@976,COG1407@1,COG1407@2 NA|NA|NA S metallophosphoesterase MAG.T22.56_01123 1237149.C900_03474 2e-125 455.7 Cytophagia ldh 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 Bacteria 47MHP@768503,4NF3I@976,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family MAG.T22.56_01124 485918.Cpin_5497 7.1e-135 486.9 Sphingobacteriia purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K03566,ko:K13713 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1INM8@117747,4NF1Z@976,COG0152@1,COG0152@2 NA|NA|NA F Phosphoribosylaminoimidazolesuccinocarboxamide synthase MAG.T22.56_01125 468059.AUHA01000002_gene706 1e-248 865.9 Sphingobacteriia hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_0688 Bacteria 1IR41@117747,4NF2P@976,COG2987@1,COG2987@2 NA|NA|NA E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate MAG.T22.56_01126 485918.Cpin_1184 4.9e-54 217.2 Sphingobacteriia ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K00991,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iPC815.YPO3360 Bacteria 1IS13@117747,4NP0N@976,COG0245@1,COG0245@2 NA|NA|NA I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) MAG.T22.56_01127 313606.M23134_00128 1.2e-97 362.8 Cytophagia Bacteria 47N2B@768503,4NFTU@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.56_01128 485918.Cpin_4033 2e-282 978.0 Sphingobacteriia lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1IQMU@117747,4NEJ9@976,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner MAG.T22.56_01129 468059.AUHA01000002_gene313 1.4e-64 253.1 Sphingobacteriia ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1ISUF@117747,4NR2U@976,COG0670@1,COG0670@2 NA|NA|NA S Inhibitor of apoptosis-promoting Bax1 MAG.T22.56_01130 1123278.KB893387_gene4368 1.8e-57 229.2 Cytophagia ypmQ ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 47PXC@768503,4NFH2@976,COG1999@1,COG1999@2 NA|NA|NA S PFAM SCO1 SenC MAG.T22.56_01131 929562.Emtol_3109 1.3e-06 60.1 Cytophagia Bacteria 47R1D@768503,4NSKP@976,COG2849@1,COG2849@2 NA|NA|NA S PFAM MORN repeat variant MAG.T22.56_01132 504472.Slin_5144 1.1e-93 349.7 Cytophagia lppC GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06910 ko00000 Bacteria 47KC4@768503,4NGHZ@976,COG1881@1,COG1881@2 NA|NA|NA S YHYH protein MAG.T22.56_01133 1123277.KB893179_gene3112 1.1e-14 86.7 Cytophagia Bacteria 47SNS@768503,4NWN1@976,COG3678@1,COG3678@2 NA|NA|NA NPTU ATP-independent chaperone mediated protein folding MAG.T22.56_01135 761193.Runsl_1457 7e-48 197.2 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47QT5@768503,4NQTP@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.56_01136 1048983.EL17_02215 3e-33 149.4 Cytophagia Bacteria 47M9V@768503,4NGA8@976,COG5661@1,COG5661@2 NA|NA|NA O secreted Zn-dependent protease MAG.T22.56_01137 700598.Niako_5804 2.5e-125 454.9 Sphingobacteriia Bacteria 1IW51@117747,4NFNA@976,COG2013@1,COG2013@2 NA|NA|NA S Mitochondrial biogenesis AIM24 MAG.T22.56_01138 313628.LNTAR_13667 7e-27 126.7 Bacteria 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria COG1607@1,COG1607@2 NA|NA|NA I acyl-coa hydrolase MAG.T22.56_01140 926556.Echvi_2137 8.4e-107 394.8 Bacteroidetes Bacteria 4PNUK@976,COG0265@1,COG0265@2 NA|NA|NA O PFAM Peptide-N-glycosidase F, C terminal MAG.T22.56_01141 925409.KI911562_gene2129 3.7e-80 304.7 Sphingobacteriia Bacteria 1IWJZ@117747,4NE77@976,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal MAG.T22.56_01142 925409.KI911562_gene2128 9.4e-83 314.3 Bacteroidetes Bacteria 4NEIS@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_01143 1356852.N008_13930 3.4e-12 79.3 Cytophagia Bacteria 2C85E@1,335NV@2,47S04@768503,4NVTV@976 NA|NA|NA MAG.T22.56_01144 925409.KI911562_gene3002 5.8e-53 213.8 Bacteroidetes 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 4NNHI@976,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.56_01145 1123248.KB893314_gene3656 6.4e-39 166.4 Sphingobacteriia groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1ITF1@117747,4NS7D@976,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T22.56_01146 485918.Cpin_6245 7.8e-254 882.9 Sphingobacteriia groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1INP2@117747,4NDZM@976,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T22.56_01147 1123248.KB893337_gene2408 1e-32 148.7 Bacteria Bacteria COG0729@1,COG0729@2,COG3210@1,COG3210@2 NA|NA|NA M surface antigen MAG.T22.56_01148 700598.Niako_2442 3.9e-22 112.8 Sphingobacteriia Bacteria 1IR3V@117747,4NDXU@976,COG0642@1,COG0745@1,COG0745@2,COG2205@2,COG3292@1,COG3292@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_01149 1123277.KB893174_gene5927 1.4e-62 247.7 Cytophagia Bacteria 47XEG@768503,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2 NA|NA|NA T Histidine kinase MAG.T22.56_01150 886377.Murru_1682 5.1e-51 208.0 Flavobacteriia ko:K02477 ko00000,ko02022 Bacteria 1I0QN@117743,4NFPV@976,COG3279@1,COG3279@2 NA|NA|NA T LytTr DNA-binding domain MAG.T22.56_01151 700598.Niako_5578 1.2e-23 115.9 Sphingobacteriia MA20_19755 Bacteria 1ITU7@117747,4NQ87@976,COG5349@1,COG5349@2 NA|NA|NA S Protein of unknown function (DUF983) MAG.T22.56_01152 485918.Cpin_0477 4.5e-218 764.2 Sphingobacteriia uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1IPMR@117747,4NE61@976,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision MAG.T22.56_01154 485918.Cpin_1851 6.8e-51 207.6 Sphingobacteriia zupT ko:K07238,ko:K11021,ko:K16267 ko00000,ko02000,ko02042 2.A.5.4.11,2.A.5.5 Bacteria 1ITHR@117747,4NG1R@976,COG0428@1,COG0428@2 NA|NA|NA P PFAM zinc iron permease MAG.T22.56_01155 504472.Slin_6313 6.3e-53 214.5 Cytophagia ko:K09973 ko00000 Bacteria 47PD6@768503,4NN4U@976,COG3735@1,COG3735@2 NA|NA|NA S TraB family MAG.T22.56_01157 1353529.M899_1701 3.2e-29 134.8 Deltaproteobacteria fcbC2 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 R01301 RC00004,RC00174 ko00000,ko00001,ko01000 Bacteria 1RF7Q@1224,2WS5R@28221,42W9H@68525,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T22.56_01158 485918.Cpin_1536 1.7e-73 282.3 Sphingobacteriia ycgM Bacteria 1INU6@117747,4NGCT@976,COG0179@1,COG0179@2 NA|NA|NA Q PFAM fumarylacetoacetate (FAA) hydrolase MAG.T22.56_01159 468059.AUHA01000002_gene562 2.2e-106 392.1 Sphingobacteriia yneE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08994 ko00000,ko02000 1.A.46.2 Bacteria 1IQHC@117747,4NEB1@976,COG3781@1,COG3781@2 NA|NA|NA S COGs COG3781 membrane protein MAG.T22.56_01160 1123355.JHYO01000012_gene688 2.6e-31 141.4 Methylocystaceae emrE ko:K03297 ko00000,ko02000 2.A.7.1 Bacteria 1MZ54@1224,2UBXR@28211,36YRH@31993,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein MAG.T22.56_01162 700598.Niako_1226 1.6e-88 332.4 Sphingobacteriia ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1IQ5P@117747,4NE2B@976,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine MAG.T22.56_01163 700598.Niako_1225 2.4e-64 252.3 Sphingobacteriia plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IS1B@117747,4NG5R@976,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T22.56_01164 1408473.JHXO01000004_gene271 3.8e-41 175.3 Bacteroidia Bacteria 2FMCQ@200643,4NI4M@976,COG5495@1,COG5495@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent MAG.T22.56_01165 1107311.Q767_07470 9.4e-19 99.8 Flavobacterium fabZ 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1I431@117743,2NWCD@237,4NSGQ@976,COG0764@1,COG0764@2 NA|NA|NA I dehydratase MAG.T22.56_01166 929713.NIASO_13475 4.2e-25 121.7 Sphingobacteriia Bacteria 1IZER@117747,29ETG@1,301R8@2,4NSXB@976 NA|NA|NA MAG.T22.56_01167 485918.Cpin_1869 4.5e-40 171.4 Sphingobacteriia lolA ko:K03634 ko00000 Bacteria 1IU2D@117747,4NT30@976,COG2834@1,COG2834@2 NA|NA|NA M Outer membrane lipoprotein carrier protein LolA MAG.T22.56_01168 485918.Cpin_1868 6.8e-48 197.6 Sphingobacteriia pgdA 3.5.1.104,3.5.1.41 ko:K01452,ko:K22278 ko00520,ko01100,map00520,map01100 R02333 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1ISZA@117747,4NM7D@976,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase MAG.T22.56_01169 1123248.KB893319_gene4032 2.5e-35 155.6 Sphingobacteriia kdsB 1.1.3.48,2.7.7.38 ko:K00979,ko:K19714 ko00540,ko01100,map00540,map01100 M00063 R03351,R11394,R11396 RC00152,RC00910,RC03427 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IXQH@117747,4NG4B@976,COG1212@1,COG1212@2 NA|NA|NA M Cytidylyltransferase MAG.T22.56_01170 1268072.PSAB_04320 1.2e-21 110.2 Paenibacillaceae ybbK 2.4.2.1,6.3.2.4 ko:K01921,ko:K03783 ko00230,ko00240,ko00473,ko00550,ko00760,ko01100,ko01110,ko01502,map00230,map00240,map00473,map00550,map00760,map01100,map01110,map01502 R01150,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00064,RC00122,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1V700@1239,26XN7@186822,4HJH0@91061,COG1683@1,COG1683@2 NA|NA|NA S Protein of unknown function (DUF523) MAG.T22.56_01171 509635.N824_06525 1.9e-127 462.6 Sphingobacteriia IV02_00930 Bacteria 1INVZ@117747,4NI22@976,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like MAG.T22.56_01173 485918.Cpin_6846 1.1e-104 387.1 Sphingobacteriia ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1ISKA@117747,4NGFA@976,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter MAG.T22.56_01174 485918.Cpin_6847 1.4e-77 296.2 Sphingobacteriia ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IRV1@117747,4NFW9@976,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T22.56_01175 1123499.KB908019_gene2376 2.8e-108 398.7 Betaproteobacteria kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 ko:K00453,ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R00678,R04323 RC00356,RC00779 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW68@1224,2VJG3@28216,COG3483@1,COG3483@2 NA|NA|NA E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety MAG.T22.56_01177 1347393.HG726025_gene2818 2.9e-13 82.0 Bacteroidaceae Bacteria 2B168@1,2FQYC@200643,31TKA@2,4ANPC@815,4NRRZ@976 NA|NA|NA S Psort location Cytoplasmic, score 8.96 MAG.T22.56_01178 1144313.PMI10_02477 5.7e-22 111.7 Flavobacterium Bacteria 1HXVY@117743,2NTUH@237,4NHRP@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.56_01179 743722.Sph21_4523 9.5e-40 170.2 Sphingobacteriia Bacteria 1IYFF@117747,4NMI9@976,COG0664@1,COG0664@2 NA|NA|NA K Cyclic nucleotide-binding domain MAG.T22.56_01180 1122176.KB903598_gene4712 1.7e-106 393.7 Bacteria Bacteria COG2866@1,COG2866@2 NA|NA|NA E metallocarboxypeptidase activity MAG.T22.56_01182 880073.Calab_2100 4e-49 203.0 Bacteria 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 R01416 RC00177 ko00000,ko00001,ko01000 Bacteria COG2957@1,COG2957@2 NA|NA|NA E agmatine deiminase activity MAG.T22.56_01185 1356852.N008_03630 4.1e-151 541.6 Cytophagia PGCP Bacteria 47M14@768503,4NE66@976,COG2234@1,COG2234@2 NA|NA|NA G Peptidase, M28 MAG.T22.56_01186 1313421.JHBV01000008_gene4350 9.5e-86 324.3 Bacteria Bacteria 2C7KZ@1,32RJE@2 NA|NA|NA MAG.T22.56_01187 485918.Cpin_2621 3.5e-43 182.2 Sphingobacteriia Bacteria 1IT5U@117747,28PX6@1,2ZCH8@2,4NNE6@976 NA|NA|NA S Domain of unknown function (DUF4349) MAG.T22.56_01189 1550091.JROE01000002_gene1135 9.2e-105 386.7 Bacteroidetes Bacteria 4NE62@976,COG1533@1,COG1533@2 NA|NA|NA L Radical SAM MAG.T22.56_01190 1550091.JROE01000002_gene1136 3.3e-63 248.4 Bacteroidetes Bacteria 2F271@1,33V57@2,4P2I3@976 NA|NA|NA MAG.T22.56_01191 1033732.CAHI01000009_gene1637 3.9e-17 95.1 Bacteroidia rbpA Bacteria 2G2C1@200643,4NV5J@976,COG0724@1,COG0724@2 NA|NA|NA S RNA recognition motif MAG.T22.56_01192 468059.AUHA01000003_gene1774 6.8e-21 108.2 Sphingobacteriia ttg2C ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1IQZY@117747,4NHT9@976,COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents periplasmic component MAG.T22.56_01193 1168034.FH5T_09290 2.4e-12 79.3 Bacteroidetes Bacteria 4NYY3@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.56_01194 1408473.JHXO01000001_gene2187 5.6e-14 84.7 Bacteroidetes Bacteria 4NYY3@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.56_01195 1408473.JHXO01000012_gene295 5.1e-40 170.6 Bacteroidia ko:K07107 ko00000,ko01000 Bacteria 2G03W@200643,4PQ2U@976,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T22.56_01196 153721.MYP_239 1.7e-11 76.6 Bacteroidetes Bacteria 4NYY3@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.56_01197 1122176.KB903534_gene2146 1e-21 109.4 Sphingobacteriia Bacteria 1ITUK@117747,2E4YQ@1,32ZSH@2,4NVKX@976 NA|NA|NA MAG.T22.56_01198 929556.Solca_0803 3.1e-88 331.6 Sphingobacteriia phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 1INS0@117747,4NDWB@976,COG1235@1,COG1235@2 NA|NA|NA S of the beta-lactamase superfamily I MAG.T22.56_01199 761193.Runsl_0191 4.1e-34 151.4 Cytophagia Bacteria 47JZP@768503,4NEX3@976,COG0526@1,COG0526@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.56_01200 485918.Cpin_1321 3e-173 615.1 Sphingobacteriia Bacteria 1IWP1@117747,4NE7V@976,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T22.56_01201 485918.Cpin_1322 4.2e-25 121.7 Sphingobacteriia 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1ITA7@117747,4NV5Q@976,COG0671@1,COG0671@2 NA|NA|NA I PFAM Phosphatidic acid phosphatase type 2 haloperoxidase MAG.T22.56_01202 485918.Cpin_1323 7.7e-112 411.0 Sphingobacteriia ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 1INY8@117747,4NE8B@976,COG0795@1,COG0795@2 NA|NA|NA S Permease, YjgP YjgQ family MAG.T22.56_01203 700598.Niako_7032 1.9e-41 175.3 Sphingobacteriia Bacteria 1ISF1@117747,4NNY1@976,COG3832@1,COG3832@2 NA|NA|NA S Pfam Activator of Hsp90 ATPase homolog 1-like protein MAG.T22.56_01205 485918.Cpin_1326 2.3e-135 488.4 Sphingobacteriia rpoD ko:K03086 ko00000,ko03021 Bacteria 1INNM@117747,4NEBF@976,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T22.56_01206 1408813.AYMG01000008_gene4016 3.2e-51 208.4 Sphingobacteriia ko:K09164 ko00000 Bacteria 1ITID@117747,4NNWJ@976,COG3358@1,COG3358@2 NA|NA|NA S Protein of unknown function (DUF1684) MAG.T22.56_01207 1123248.KB893348_gene194 7.4e-62 245.0 Sphingobacteriia Bacteria 1IWR7@117747,4NJMF@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2 NA|NA|NA T Y_Y_Y domain MAG.T22.56_01208 485918.Cpin_6223 4.1e-243 847.0 Sphingobacteriia lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1IQUN@117747,4NFHV@976,COG0019@1,COG0019@2 NA|NA|NA E decarboxylase MAG.T22.56_01209 700598.Niako_4420 1.2e-52 213.4 Sphingobacteriia Bacteria 1IP6X@117747,4NE8D@976,COG0697@1,COG0697@2 NA|NA|NA EG PFAM EamA-like transporter family MAG.T22.56_01211 714943.Mucpa_3082 2.9e-19 102.8 Bacteroidetes Bacteria 2DUN4@1,32UXH@2,4NTVE@976 NA|NA|NA MAG.T22.56_01212 391598.FBBAL38_09802 1.2e-30 140.6 Flavobacteriia Bacteria 1I4D0@117743,2DUN4@1,32UXH@2,4NTVE@976 NA|NA|NA MAG.T22.56_01214 925409.KI911562_gene2778 2.9e-77 295.4 Sphingobacteriia gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 R01961 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1ISQ1@117747,4NEV4@976,COG2971@1,COG2971@2 NA|NA|NA G N-acetylglucosamine kinase MAG.T22.56_01215 485917.Phep_1274 1.1e-46 194.5 Bacteroidetes 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 ko:K07315,ko:K12132,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021 Bacteria 4NRUV@976,COG3290@1,COG3290@2 NA|NA|NA T PAS domain MAG.T22.56_01216 485918.Cpin_6314 6e-12 77.4 Bacteroidetes Bacteria 2DM52@1,32UG7@2,4NSYJ@976 NA|NA|NA MAG.T22.56_01217 1313421.JHBV01000028_gene1857 5.8e-127 462.6 Bacteroidetes ko:K12287 ko00000,ko02044 Bacteria 4NJ47@976,COG1357@1,COG1357@2,COG1404@1,COG1404@2,COG3291@1,COG3291@2 NA|NA|NA U PFAM PKD domain MAG.T22.56_01218 1123248.KB893322_gene568 3e-41 177.2 Sphingobacteriia Bacteria 1IV4S@117747,4NDZC@976,COG1361@1,COG1361@2,COG3291@1,COG3291@2,COG4386@1,COG4386@2 NA|NA|NA M Immunoglobulin MAG.T22.56_01219 1121373.KB903652_gene1472 1.4e-46 194.9 Bacteroidetes Bacteria 4PPK0@976,COG3291@1,COG3291@2,COG5184@1,COG5184@2 NA|NA|NA G amine dehydrogenase activity MAG.T22.56_01228 929713.NIASO_17725 3.4e-74 285.4 Sphingobacteriia VP2476 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1IRKY@117747,4NIB3@976,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.56_01229 485918.Cpin_0791 5e-67 260.8 Sphingobacteriia nadD 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1IRZ1@117747,4NFQI@976,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) MAG.T22.56_01230 485918.Cpin_0745 7.5e-15 86.3 Sphingobacteriia feoA ko:K03709,ko:K04758 ko00000,ko02000,ko03000 Bacteria 1IU0B@117747,4NUWI@976,COG1918@1,COG1918@2 NA|NA|NA P FeoA MAG.T22.56_01231 485918.Cpin_0746 7.3e-34 150.2 Sphingobacteriia ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1ISZQ@117747,4NS93@976,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA MAG.T22.56_01232 1123248.KB893314_gene3415 6.9e-69 267.3 Sphingobacteriia 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 ko:K06177,ko:K06179,ko:K06180 ko00000,ko01000,ko03009,ko03016 Bacteria 1IQTT@117747,4NHKH@976,COG0564@1,COG0564@2 NA|NA|NA J Pseudouridine synthase MAG.T22.56_01233 1122605.KB893646_gene45 3.1e-27 127.9 Sphingobacteriia gldC Bacteria 1ISTG@117747,2AGY9@1,3176X@2,4NQD4@976 NA|NA|NA S TIGRFAM Gliding motility-associated protein, GldC MAG.T22.56_01234 485918.Cpin_1045 4.2e-42 177.6 Sphingobacteriia yqeY ko:K09117 ko00000 Bacteria 1IT3W@117747,4NQFI@976,COG1610@1,COG1610@2 NA|NA|NA S PFAM Yqey-like protein MAG.T22.56_01235 700598.Niako_6587 3.1e-21 108.6 Sphingobacteriia cvpA ko:K03558 ko00000 Bacteria 1IZI5@117747,4P9DM@976,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein MAG.T22.56_01236 156889.Mmc1_1121 2.1e-49 202.2 Alphaproteobacteria pabA GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135 Bacteria 1MV5Y@1224,2TU3N@28211,COG0512@1,COG0512@2 NA|NA|NA EH Anthranilate synthase MAG.T22.56_01237 1150600.ADIARSV_2227 1.7e-48 199.5 Sphingobacteriia Bacteria 1IRYT@117747,2ZZTD@2,4NNMY@976,arCOG05416@1 NA|NA|NA S TIGRFAM lycopene cyclase domain MAG.T22.56_01238 1123248.KB893348_gene313 5.2e-55 220.7 Sphingobacteriia crtZ 1.14.15.24 ko:K15746 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00372 R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747 RC00478,RC00704,RC02629 ko00000,ko00001,ko00002,ko01000 Bacteria 1IT6S@117747,4NMA9@976,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase MAG.T22.56_01239 1454007.JAUG01000020_gene1619 2.6e-32 145.6 Sphingobacteriia cruF 5.5.1.19 ko:K22502 ko00906,map00906 R03824,R05341 RC01004 ko00000,ko00001,ko01000 Bacteria 1IT8X@117747,4NQR7@976,COG2324@1,COG2324@2 NA|NA|NA S Carotenoid biosynthesis protein MAG.T22.56_01240 45351.EDO25493 2.5e-70 273.5 Eukaryota Eukaryota COG0457@1,KOG1124@2759 NA|NA|NA O cellular component assembly MAG.T22.56_01241 1123248.KB893319_gene4074 3.5e-39 168.7 Sphingobacteriia birA 6.3.4.15 ko:K03523,ko:K03524 ko00780,ko01100,ko02010,map00780,map01100,map02010 M00581,M00582 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 2.A.88.1,2.A.88.2 Bacteria 1IS0E@117747,4NHCH@976,COG0340@1,COG0340@2 NA|NA|NA H PFAM Biotin lipoate A B protein ligase MAG.T22.56_01242 485918.Cpin_0467 1.5e-35 155.6 Sphingobacteriia rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1ISS0@117747,4NSKK@976,COG0799@1,COG0799@2 NA|NA|NA S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation MAG.T22.56_01244 485918.Cpin_5841 2.5e-144 519.2 Sphingobacteriia sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 ko:K04773 ko00000,ko01000,ko01002 Bacteria 1IP6H@117747,4NES1@976,COG0616@1,COG0616@2 NA|NA|NA OU signal peptide peptidase SppA, 67K type MAG.T22.56_01246 1406840.Q763_12480 3.7e-62 244.6 Flavobacterium Bacteria 1I17E@117743,2NSUH@237,4NMAH@976,COG2335@1,COG2335@2 NA|NA|NA M Fasciclin MAG.T22.56_01247 925409.KI911562_gene2360 2.9e-204 718.0 Sphingobacteriia sdaA GO:0003674,GO:0003824,GO:0003941,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 iECSP_1301.ECSP_4084,iECUMN_1333.ECUMN_2106 Bacteria 1IQ2K@117747,4NENR@976,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase MAG.T22.56_01248 1122605.KB893625_gene2083 1.3e-107 396.7 Sphingobacteriia waaA GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016 GT30 Bacteria 1IQKA@117747,4NESA@976,COG1519@1,COG1519@2 NA|NA|NA M transferase MAG.T22.56_01249 761193.Runsl_3570 7e-167 593.6 Cytophagia stsA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 ko:K19715 R11395 RC00160 ko00000,ko01000,ko01005 Bacteria 47MSW@768503,4NG9W@976,COG0399@1,COG0399@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.56_01250 761193.Runsl_3569 1.2e-165 589.3 Cytophagia kdnB GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.1,1.1.3.48 ko:K13954,ko:K19714 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R04880,R05233,R05234,R06917,R06927,R11394 RC00050,RC00088,RC00099,RC00116,RC00649,RC03427 ko00000,ko00001,ko01000,ko01005 Bacteria 47NV0@768503,4PKHV@976,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase MAG.T22.56_01251 1313301.AUGC01000003_gene2099 4.6e-125 454.1 Bacteroidetes kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 4NENN@976,COG2877@1,COG2877@2 NA|NA|NA M Belongs to the KdsA family MAG.T22.56_01252 761193.Runsl_0202 9.4e-133 479.9 Cytophagia tal 2.2.1.2 ko:K00616,ko:K07003 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 47KKQ@768503,4NIUX@976,COG0176@1,COG0176@2,COG2905@1,COG2905@2 NA|NA|NA GT Transaldolase/Fructose-6-phosphate aldolase MAG.T22.56_01253 1123277.KB893239_gene1226 3e-53 215.3 Cytophagia neuA 2.7.7.43,3.1.3.45 ko:K00983,ko:K03270 ko00520,ko00540,ko01100,map00520,map00540,map01100 M00063 R01117,R03350,R04215 RC00017,RC00152 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 47PAE@768503,4NMFZ@976,COG1778@1,COG1778@2 NA|NA|NA S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate MAG.T22.56_01254 761193.Runsl_3684 1.7e-86 325.9 Cytophagia kdsB 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 47M2Z@768503,4NG4B@976,COG1212@1,COG1212@2 NA|NA|NA M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria MAG.T22.56_01257 760192.Halhy_3019 3.7e-26 125.9 Bacteroidetes Bacteria 4NJWY@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_01259 649349.Lbys_2141 1.6e-11 77.0 Cytophagia Bacteria 2BXF6@1,33RKG@2,47U2X@768503,4P1F5@976 NA|NA|NA MAG.T22.56_01261 929556.Solca_2223 3e-49 201.8 Sphingobacteriia ko:K03088 ko00000,ko03021 Bacteria 1IS89@117747,4NNBY@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_01262 929556.Solca_2224 3.1e-77 295.4 Sphingobacteriia Bacteria 1IS2K@117747,4NMA2@976,COG3712@1,COG3712@2 NA|NA|NA PT PFAM FecR protein MAG.T22.56_01263 485918.Cpin_3939 1.7e-71 277.3 Sphingobacteriia Bacteria 1INXJ@117747,4NIGK@976,COG3078@1,COG3078@2 NA|NA|NA P TonB-dependent receptor MAG.T22.56_01264 929556.Solca_2226 7.8e-35 154.8 Sphingobacteriia Bacteria 1IRTZ@117747,4NK7M@976,COG3078@1,COG3078@2 NA|NA|NA S GTPase activator activity MAG.T22.56_01266 926549.KI421517_gene1008 1.9e-171 609.8 Cytophagia Bacteria 47K3W@768503,4PKVH@976,COG1629@1,COG1629@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.56_01267 362418.IW19_00060 4.8e-13 81.6 Flavobacterium Bacteria 1I1B3@117743,2NTX1@237,4NSAQ@976,COG3595@1,COG3595@2 NA|NA|NA S Putative auto-transporter adhesin, head GIN domain MAG.T22.56_01268 1121104.AQXH01000001_gene1263 1.8e-58 233.0 Sphingobacteriia Bacteria 1IQ4P@117747,4NDXU@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_01269 925409.KI911562_gene5 1.9e-67 261.9 Sphingobacteriia rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IRJ7@117747,4NEEM@976,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA MAG.T22.56_01271 925409.KI911562_gene7 3.3e-35 157.5 Bacteroidetes Bacteria 4NKIP@976,COG2374@1,COG2374@2,COG2911@1,COG2911@2 NA|NA|NA U Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_01272 1122621.ATZA01000020_gene3988 9.9e-283 979.2 Sphingobacteriia ko:K16089 ko00000,ko02000 1.B.14.1,1.B.14.10 Bacteria 1IQZ4@117747,4NF05@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent receptor MAG.T22.56_01273 700598.Niako_1728 7.4e-192 677.2 Bacteroidetes Bacteria 2CM4J@1,2Z7U5@2,4NK94@976 NA|NA|NA MAG.T22.56_01274 485918.Cpin_0854 1.2e-151 542.7 Sphingobacteriia recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1INW2@117747,4NEXT@976,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage MAG.T22.56_01275 1267211.KI669560_gene2058 1.6e-270 939.1 Sphingobacteriia pqqL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07263 ko00000,ko01000,ko01002 Bacteria 1IP4P@117747,4NFY0@976,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 MAG.T22.56_01276 1121373.KB903652_gene1472 4.8e-84 320.1 Bacteroidetes Bacteria 4PPK0@976,COG3291@1,COG3291@2,COG5184@1,COG5184@2 NA|NA|NA G amine dehydrogenase activity MAG.T22.56_01277 1120966.AUBU01000005_gene3545 3.4e-103 382.1 Cytophagia Bacteria 47M48@768503,4NF4G@976,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V MAG.T22.56_01278 1341181.FLJC2902T_01520 3.8e-55 221.9 Flavobacterium Bacteria 1HY86@117743,2NVPE@237,4NJN9@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_01279 1223410.KN050846_gene2418 2.9e-06 60.5 Flavobacteriia Bacteria 1HZTN@117743,4NJHN@976,COG1520@1,COG1520@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_01280 768706.Desor_2727 2.4e-38 166.0 Peptococcaceae ko:K07124 ko00000 Bacteria 1UZHA@1239,248C8@186801,265H8@186807,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.56_01281 1288963.ADIS_1228 8.5e-32 143.3 Cytophagia Bacteria 2DMYZ@1,32UGH@2,47R9K@768503,4NTDD@976 NA|NA|NA S Domain of unknown function (DUF4345) MAG.T22.56_01283 700598.Niako_2186 4e-12 79.0 Sphingobacteriia Bacteria 1IYX8@117747,2EPP0@1,33H9M@2,4NXT6@976 NA|NA|NA MAG.T22.56_01284 1443665.JACA01000058_gene1078 4.6e-50 204.1 Aquimarina Bacteria 1I1QV@117743,2YIRZ@290174,4NP23@976,COG0251@1,COG0251@2 NA|NA|NA J YjgF/chorismate_mutase-like, putative endoribonuclease MAG.T22.56_01285 929556.Solca_2252 1.2e-40 172.9 Bacteroidetes Bacteria 4NQBY@976,COG2318@1,COG2318@2 NA|NA|NA S Damage-inducible protein DinB MAG.T22.56_01287 485918.Cpin_6612 3.4e-249 867.5 Sphingobacteriia pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 1IP4J@117747,4NEWT@976,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates MAG.T22.56_01288 1123248.KB893320_gene3844 7.5e-191 674.5 Sphingobacteriia Bacteria 1IQ3X@117747,4NF88@976,COG1629@1,COG1629@2 NA|NA|NA P Outer membrane protein beta-barrel family MAG.T22.56_01289 1123248.KB893381_gene1093 4.7e-57 228.0 Sphingobacteriia Bacteria 1IS37@117747,28NAE@1,2ZBE7@2,4NJNX@976 NA|NA|NA S Protein of unknown function (Porph_ging) MAG.T22.56_01290 485918.Cpin_0494 1.3e-178 632.5 Sphingobacteriia metC 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K10764 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1INVN@117747,4NF0Q@976,COG0626@1,COG0626@2 NA|NA|NA E PFAM Cys Met metabolism MAG.T22.56_01291 1267211.KI669560_gene2776 1.4e-144 519.2 Sphingobacteriia ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1IR3Y@117747,4NEB9@976,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing MAG.T22.56_01292 1168034.FH5T_09110 2e-123 449.1 Bacteroidia Bacteria 2FQFD@200643,4NEZI@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein MAG.T22.56_01293 1122605.KB893637_gene3156 1.8e-66 259.2 Sphingobacteriia gmhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83 ko:K00966,ko:K03273,ko:K15669 ko00051,ko00520,ko00540,ko01100,ko01110,map00051,map00520,map00540,map01100,map01110 M00064,M00114,M00361,M00362 R00885,R05647,R09771,R09772 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IPMP@117747,4NFDB@976,COG0241@1,COG0241@2,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase MAG.T22.56_01294 700598.Niako_2547 9.5e-133 479.9 Sphingobacteriia hddA 2.7.1.168 ko:K07031 ko00540,map00540 R09770 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1IU21@117747,4NHEN@976,COG2605@1,COG2605@2 NA|NA|NA S GHMP kinases N terminal domain MAG.T22.56_01295 485918.Cpin_0437 8.2e-11 73.6 Sphingobacteriia fjo27 Bacteria 1ITWF@117747,4NVME@976,COG5652@1,COG5652@2 NA|NA|NA S VanZ like family MAG.T22.56_01296 485918.Cpin_0436 1.5e-47 195.7 Sphingobacteriia gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1IT1E@117747,4NQ35@976,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein MAG.T22.56_01297 485918.Cpin_2195 1.5e-35 156.8 Sphingobacteriia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1IXWG@117747,4NJQN@976,COG3291@1,COG3291@2 NA|NA|NA M PKD domain containing protein MAG.T22.56_01299 485918.Cpin_3684 5.6e-105 387.5 Sphingobacteriia ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1IQKP@117747,4NEI0@976,COG0248@1,COG0248@2 NA|NA|NA FP PFAM Ppx GppA phosphatase MAG.T22.56_01300 485918.Cpin_3685 9e-247 859.8 Sphingobacteriia ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iSbBS512_1146.SbBS512_E2875 Bacteria 1IPGC@117747,4NE3P@976,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) MAG.T22.56_01301 1150600.ADIARSV_1954 5.8e-43 180.6 Sphingobacteriia hldE 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1ISYY@117747,4NNKK@976,COG0615@1,COG0615@2 NA|NA|NA IM Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose MAG.T22.56_01302 485918.Cpin_3687 1.4e-64 253.4 Sphingobacteriia ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1ISJK@117747,4NGPD@976,COG0392@1,COG0392@2 NA|NA|NA S Lysylphosphatidylglycerol synthase TM region MAG.T22.56_01303 925409.KI911562_gene2668 4.4e-42 177.2 Sphingobacteriia panD 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1IT2H@117747,4NQ42@976,COG0853@1,COG0853@2 NA|NA|NA H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine MAG.T22.56_01304 1123248.KB893324_gene1767 5.4e-48 197.2 Sphingobacteriia rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IRUM@117747,4NNRP@976,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA MAG.T22.56_01305 485918.Cpin_6994 9.3e-32 142.5 Sphingobacteriia rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISSH@117747,4NSAR@976,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit MAG.T22.56_01306 485918.Cpin_6993 6.9e-38 163.3 Sphingobacteriia rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1ISJI@117747,4NQ9W@976,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA MAG.T22.56_01307 1122225.AULQ01000004_gene1978 1.8e-06 60.8 Flavobacteriia Bacteria 1HXFZ@117743,4NI6H@976,COG3391@1,COG3391@2 NA|NA|NA DZ Conserved repeat domain MAG.T22.56_01308 1121904.ARBP01000013_gene449 4.2e-36 157.9 Cytophagia Bacteria 2DVQJ@1,32UZZ@2,47RBJ@768503,4P9HJ@976 NA|NA|NA MAG.T22.56_01309 925409.KI911562_gene2169 0.0 1101.3 Sphingobacteriia yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1IPB3@117747,4NETD@976,COG2183@1,COG2183@2 NA|NA|NA K Tex-like protein N-terminal domain MAG.T22.56_01310 1183438.GKIL_2649 3.6e-93 348.6 Bacteria Bacteria COG3503@1,COG3503@2 NA|NA|NA J Membrane MAG.T22.56_01311 1123248.KB893323_gene1622 1.9e-30 138.3 Sphingobacteriia aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 ko:K00684 R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 Bacteria 1IP1V@117747,4NG3A@976,COG2360@1,COG2360@2 NA|NA|NA O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine MAG.T22.56_01312 1229487.AMYW01000016_gene2477 1.2e-12 78.6 Flavobacterium Bacteria 1I6KH@117743,2EG5P@1,2NY4R@237,339XJ@2,4NY3A@976 NA|NA|NA MAG.T22.56_01313 638303.Thal_0347 3.8e-24 119.8 Aquificae speC 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2G3J8@200783,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T22.56_01314 760192.Halhy_0879 0.0 1473.8 Sphingobacteriia Bacteria 1IVGI@117747,4P0UI@976,COG0823@1,COG0823@2,COG1228@1,COG1228@2 NA|NA|NA QU Amidohydrolase family MAG.T22.56_01315 402612.FP0881 6.5e-114 417.5 Flavobacterium ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 1HXZJ@117743,2NSC3@237,4NDW5@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.56_01316 925409.KI911562_gene1947 0.0 1712.2 Bacteroidetes ko:K15726 ko00000,ko02000 2.A.6.1.2 Bacteria 4P36A@976,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.56_01317 525257.HMPREF0204_13169 9.8e-12 76.3 Chryseobacterium Bacteria 1I5CE@117743,2EAT9@1,334V5@2,3ZSK6@59732,4NUP8@976 NA|NA|NA MAG.T22.56_01318 1406840.Q763_09065 1e-82 314.7 Flavobacterium Bacteria 1I3IV@117743,2NSFE@237,4NRYC@976,COG1520@1,COG1520@2,COG3291@1,COG3291@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_01319 1121898.Q766_06970 1.2e-188 667.9 Flavobacterium Bacteria 1I0VP@117743,2NTV3@237,4NFRR@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain MAG.T22.56_01320 925409.KI911562_gene1505 8.5e-42 177.2 Bacteroidetes Bacteria 4NN4D@976,COG2197@1,COG2197@2 NA|NA|NA T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.56_01326 485918.Cpin_0365 0.0 1369.0 Sphingobacteriia bepE_4 ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 Bacteria 1IP63@117747,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.56_01327 1123248.KB893348_gene202 2.5e-88 331.6 Sphingobacteriia sodB 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 1IQF9@117747,4NDZ4@976,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T22.56_01329 926562.Oweho_0645 1.3e-12 80.1 Bacteroidetes Bacteria 2CHA0@1,2ZMNX@2,4P7XE@976 NA|NA|NA MAG.T22.56_01330 1313421.JHBV01000035_gene2506 4.1e-137 495.4 Sphingobacteriia Bacteria 1IPV6@117747,4NDTY@976,COG0457@1,COG0457@2 NA|NA|NA S Cytochrome c554 and c-prime MAG.T22.56_01331 925409.KI911562_gene2834 1.8e-160 572.4 Sphingobacteriia tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1IPGT@117747,4NF19@976,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) MAG.T22.56_01332 485918.Cpin_3365 3.2e-39 169.1 Sphingobacteriia ko:K12976 ko00000,ko01000,ko01005 Bacteria 1IYEN@117747,4NQ11@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.56_01333 929556.Solca_4227 2.5e-152 545.4 Sphingobacteriia hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1IQNJ@117747,4NE8N@976,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase MAG.T22.56_01334 700598.Niako_7057 8.5e-52 209.9 Sphingobacteriia ptpA 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1IYAU@117747,4NNQZ@976,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphotyrosine protein phosphatase MAG.T22.56_01336 760192.Halhy_5095 0.0 1258.8 Sphingobacteriia katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 1IQZ2@117747,4NG30@976,COG0376@1,COG0376@2 NA|NA|NA P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity MAG.T22.56_01338 880071.Fleli_3464 3.4e-113 414.8 Cytophagia oxyR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141 ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 47JGK@768503,4NGZ5@976,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family MAG.T22.56_01339 926556.Echvi_3269 2.1e-18 100.1 Cytophagia 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 47Q56@768503,4NP9G@976,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family MAG.T22.56_01341 118161.KB235922_gene1926 2.6e-07 63.9 Pleurocapsales Bacteria 1GP04@1117,3VMQ4@52604,COG1520@1,COG1520@2,COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T22.56_01342 1178825.ALIH01000001_gene2581 1e-11 77.8 Flavobacteriia 3.4.24.28 ko:K01400 ko00000,ko01000,ko01002 Bacteria 1HY9Y@117743,4NF8H@976,COG3227@1,COG3227@2 NA|NA|NA E Thermolysin metallopeptidase, alpha-helical domain MAG.T22.56_01343 1270196.JCKI01000002_gene298 4.6e-35 154.1 Sphingobacteriia Bacteria 1ISR5@117747,2ATIR@1,31J2R@2,4NR1Z@976 NA|NA|NA S Domain of unknown function (DUF4268) MAG.T22.56_01344 1121895.Q765_18450 1.3e-06 60.5 Flavobacterium ko:K13735 ko05100,map05100 ko00000,ko00001 Bacteria 1I00F@117743,2NUTP@237,4NFXV@976,COG2911@1,COG2911@2,COG4886@1,COG4886@2,COG4935@1,COG4935@2 NA|NA|NA O Pkd domain containing protein MAG.T22.56_01347 1144312.PMI09_00559 1.2e-55 223.8 Rhizobiaceae 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 Bacteria 1PFCX@1224,2VAZ7@28211,4BHPX@82115,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T22.56_01348 113395.AXAI01000003_gene5857 1.8e-85 322.8 Bacteria Bacteria COG2227@1,COG2227@2 NA|NA|NA H 3-demethylubiquinone-9 3-O-methyltransferase activity MAG.T22.56_01349 1124780.ANNU01000044_gene504 3.6e-103 381.7 Cytophagia 1.14.15.3 ko:K00496,ko:K10616,ko:K15757 ko00071,ko00622,ko00623,ko00930,ko01100,ko01120,ko01220,map00071,map00622,map00623,map00930,map01100,map01120,map01220 M00419,M00537 R01347,R02281,R02550,R05266,R05288,R05442,R05443,R06945 RC00269,RC00478 ko00000,ko00001,ko00002,ko01000 Bacteria 47UEF@768503,4NIC2@976,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T22.56_01350 485918.Cpin_4710 3.8e-40 170.6 Sphingobacteriia trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1ISZS@117747,4NQ5B@976,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family MAG.T22.56_01351 1267211.KI669560_gene1821 0.0 1600.1 Sphingobacteriia dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1IR52@117747,4NFA0@976,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III alpha subunit MAG.T22.56_01353 1122605.KB893626_gene2825 5.5e-10 70.9 Sphingobacteriia Bacteria 1IZMC@117747,2DI7A@1,30289@2,4PJ60@976 NA|NA|NA MAG.T22.56_01354 1349785.BAUG01000004_gene357 4.5e-09 68.6 Bacteroidetes Bacteria 28UV9@1,2ZGZ9@2,4P8CI@976 NA|NA|NA MAG.T22.56_01355 471854.Dfer_5094 1.6e-15 90.1 Cytophagia Bacteria 2DE6B@1,2ZKPA@2,47WPC@768503,4P8R5@976 NA|NA|NA MAG.T22.56_01356 700598.Niako_5601 4.3e-114 418.3 Sphingobacteriia pabB 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1IPYM@117747,4NECR@976,COG0147@1,COG0147@2 NA|NA|NA EH PFAM chorismate binding MAG.T22.56_01358 5207.AAW42427 2.6e-20 104.8 Tremellales ADE12 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0004019,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006106,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034404,GO:0034641,GO:0034654,GO:0042221,GO:0042278,GO:0042451,GO:0042455,GO:0043436,GO:0043565,GO:0043648,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046686,GO:0050896,GO:0051716,GO:0055086,GO:0061483,GO:0070887,GO:0071241,GO:0071248,GO:0071276,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1990837 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Fungi 38HVH@33154,3NWD9@4751,3UZ9B@5204,3VDCH@5234,COG0104@1,KOG1355@2759 NA|NA|NA F Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first MAG.T22.56_01360 742817.HMPREF9449_01124 1.1e-81 309.7 Porphyromonadaceae rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1718 Bacteria 22WA0@171551,2FM7Z@200643,4NDXB@976,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family MAG.T22.56_01361 700598.Niako_0350 6.9e-54 217.6 Sphingobacteriia Bacteria 1IQUU@117747,4PKY5@976,COG4206@1,COG4206@2 NA|NA|NA H PFAM TonB-dependent Receptor Plug Domain MAG.T22.56_01362 700598.Niako_0350 1e-125 457.2 Sphingobacteriia Bacteria 1IQUU@117747,4PKY5@976,COG4206@1,COG4206@2 NA|NA|NA H PFAM TonB-dependent Receptor Plug Domain MAG.T22.56_01363 374847.Kcr_0638 1.9e-13 84.3 Archaea 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Archaea arCOG02559@1,arCOG02559@2157 NA|NA|NA P by modhmm MAG.T22.56_01364 999419.HMPREF1077_01654 5.8e-39 167.9 Porphyromonadaceae Bacteria 22ZYW@171551,2FUZW@200643,4NNHE@976,COG3279@1,COG3279@2 NA|NA|NA T LytTr DNA-binding domain MAG.T22.56_01369 485918.Cpin_6945 6.3e-10 70.5 Sphingobacteriia Bacteria 1ITZI@117747,2EGFG@1,33A7G@2,4P9MA@976 NA|NA|NA MAG.T22.56_01370 1166018.FAES_1983 1.4e-36 160.2 Cytophagia Bacteria 47P1E@768503,4NIIB@976,COG4313@1,COG4313@2 NA|NA|NA C Protein involved in meta-pathway of phenol degradation MAG.T22.56_01373 485918.Cpin_0862 8.7e-169 600.1 Sphingobacteriia rumA 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1IQPD@117747,4NFP1@976,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family MAG.T22.56_01374 485918.Cpin_0863 2.2e-98 366.3 Sphingobacteriia Bacteria 1IXCQ@117747,4NHEC@976,COG0526@1,COG0526@2 NA|NA|NA CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.56_01375 485918.Cpin_0863 6.1e-93 348.2 Sphingobacteriia Bacteria 1IXCQ@117747,4NHEC@976,COG0526@1,COG0526@2 NA|NA|NA CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.56_01376 1237149.C900_03125 6.1e-112 411.8 Cytophagia 5.2.1.8 ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 47K78@768503,4NGIR@976,COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl isomerase MAG.T22.56_01377 485918.Cpin_1417 5.3e-174 617.5 Sphingobacteriia ko:K07576,ko:K07577 ko00000 Bacteria 1IQ1N@117747,4NESD@976,COG1236@1,COG1236@2 NA|NA|NA J exonuclease of the beta-lactamase fold involved in RNA processing MAG.T22.56_01378 485918.Cpin_3671 9.5e-233 813.1 Sphingobacteriia rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1IPGD@117747,4NE7T@976,COG0557@1,COG0557@2 NA|NA|NA K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs MAG.T22.56_01379 925409.KI911562_gene2496 2.9e-91 342.0 Sphingobacteriia idsA 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1INSC@117747,4NEGQ@976,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T22.56_01380 1168034.FH5T_01205 1.7e-67 263.5 Bacteroidia Bacteria 2FQT6@200643,4NFD3@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_01381 485918.Cpin_5934 2.5e-193 681.4 Sphingobacteriia ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 1INQM@117747,4NF6I@976,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate MAG.T22.56_01382 1191523.MROS_0300 1.7e-64 253.4 Bacteria ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_01383 485918.Cpin_5933 1.8e-237 830.1 Sphingobacteriia Bacteria 1IPAB@117747,4NF7F@976,COG2911@1,COG2911@2 NA|NA|NA S TamB, inner membrane protein subunit of TAM complex MAG.T22.56_01384 1123248.KB893314_gene3538 1e-306 1058.9 Sphingobacteriia pep GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 1IRD1@117747,4NFJS@976,COG1505@1,COG1505@2 NA|NA|NA E Prolyl endopeptidase MAG.T22.56_01385 865938.Weevi_1696 4.3e-69 267.7 Flavobacteriia punA 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1HWSP@117743,4NE4J@976,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate MAG.T22.56_01386 1123248.KB893318_gene4162 4.7e-72 279.3 Sphingobacteriia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1ISVQ@117747,4NI2R@976,COG4206@1,COG4206@2 NA|NA|NA H Putative porin MAG.T22.56_01387 485918.Cpin_6840 0.0 1248.8 Sphingobacteriia sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 1IQYB@117747,4NEU9@976,COG0567@1,COG0567@2 NA|NA|NA C 2-oxoglutarate dehydrogenase, E1 MAG.T22.56_01388 485918.Cpin_6845 5.3e-24 116.7 Sphingobacteriia acpP-1 ko:K02078 ko00000,ko00001 Bacteria 1IYTB@117747,4NSFU@976,COG0236@1,COG0236@2 NA|NA|NA IQ Phosphopantetheine attachment site MAG.T22.56_01389 485918.Cpin_6844 7.1e-119 434.1 Sphingobacteriia fabF-1 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458,ko:K11054 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IRGP@117747,4NFC8@976,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T22.56_01390 485918.Cpin_6843 2.8e-66 259.2 Sphingobacteriia Bacteria 1ISE9@117747,4NEU6@976,COG0304@1,COG0304@2 NA|NA|NA IQ Beta-ketoacyl synthase, N-terminal domain MAG.T22.56_01391 1122226.AUHX01000010_gene1562 2e-56 225.7 Flavobacteriia sanA ko:K03748 ko00000 Bacteria 1I1DV@117743,4NNQS@976,COG2949@1,COG2949@2 NA|NA|NA S membrane MAG.T22.56_01392 1121373.KB903642_gene3692 9e-33 147.5 Cytophagia Bacteria 47M55@768503,4NI2H@976,COG5343@1,COG5343@2 NA|NA|NA S PFAM Anti-sigma-K factor RskA MAG.T22.56_01393 643867.Ftrac_3318 5.3e-45 187.6 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47QEF@768503,4NMIY@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_01394 485918.Cpin_1904 2.4e-72 278.5 Sphingobacteriia def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 1IRF3@117747,4NFB4@976,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions MAG.T22.56_01395 1122605.KB893645_gene1034 2.2e-40 171.8 Sphingobacteriia yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1ISBS@117747,4NQ8B@976,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA MAG.T22.56_01396 700598.Niako_2629 1.6e-12 80.1 Sphingobacteriia dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1IR9Y@117747,4NENT@976,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication MAG.T22.56_01397 929713.NIASO_05390 1.4e-98 365.9 Sphingobacteriia carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383 Bacteria 1IPSN@117747,4NEQI@976,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family MAG.T22.56_01398 485918.Cpin_2021 1.9e-127 462.2 Sphingobacteriia ltd 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 1IQ61@117747,4NE3U@976,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.56_01399 700598.Niako_2054 1.2e-91 342.8 Sphingobacteriia cobB ko:K12410 ko00000,ko01000 Bacteria 1INTC@117747,4NE9Q@976,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form MAG.T22.56_01400 234267.Acid_7379 8.8e-08 65.1 Bacteria Bacteria 2A08G@1,33ENC@2 NA|NA|NA MAG.T22.56_01402 485918.Cpin_3090 7.4e-135 486.9 Sphingobacteriia ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1IPD8@117747,4NE9Z@976,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) MAG.T22.56_01403 1210884.HG799464_gene10433 1.1e-28 134.4 Bacteria hetM Bacteria COG0451@1,COG0451@2 NA|NA|NA GM ADP-glyceromanno-heptose 6-epimerase activity MAG.T22.56_01404 925409.KI911562_gene2249 2.3e-218 764.6 Sphingobacteriia icd 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1INSE@117747,4NDY2@976,COG0538@1,COG0538@2 NA|NA|NA C Belongs to the isocitrate and isopropylmalate dehydrogenases family MAG.T22.56_01407 714943.Mucpa_6153 4.1e-90 339.3 Sphingobacteriia ladS ko:K20971 ko02025,map02025 ko00000,ko00001,ko01001,ko02022 Bacteria 1INXK@117747,4NF5X@976,COG0457@1,COG0457@2,COG4251@1,COG4251@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_01408 485918.Cpin_0934 1.4e-51 209.5 Sphingobacteriia gldD Bacteria 1ISN4@117747,293VW@1,2ZRB2@2,4NMK7@976 NA|NA|NA S TIGRFAM gliding motility-associated lipoprotein GldD MAG.T22.56_01409 485918.Cpin_6876 1.4e-31 142.1 Sphingobacteriia 2.7.11.1,4.6.1.1 ko:K01768,ko:K12132 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001 Bacteria 1ISVX@117747,4NSNP@976,COG4191@1,COG4191@2 NA|NA|NA T Protein of unknown function (DUF3467) MAG.T22.56_01410 1267211.KI669560_gene834 1.6e-50 205.7 Sphingobacteriia dps GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K04047 ko00000,ko03036 Bacteria 1ISAY@117747,4NQDD@976,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family MAG.T22.56_01411 1267211.KI669560_gene835 3.8e-43 181.8 Sphingobacteriia Bacteria 1IZJQ@117747,2CZCF@1,32T62@2,4NT3B@976 NA|NA|NA MAG.T22.56_01412 755732.Fluta_3723 9.5e-60 236.1 Bacteroidetes Bacteria 2B9TV@1,3236R@2,4P2DP@976 NA|NA|NA MAG.T22.56_01414 1123248.KB893330_gene450 2.1e-35 155.6 Sphingobacteriia hscB ko:K03686,ko:K04082,ko:K05516,ko:K05801 ko00000,ko03029,ko03036,ko03110 Bacteria 1ITFJ@117747,4NSI9@976,COG0484@1,COG0484@2 NA|NA|NA O HSCB C-terminal oligomerisation domain MAG.T22.56_01415 925409.KI911562_gene2512 4.9e-128 464.5 Sphingobacteriia sdh 1.5.1.7,1.5.1.8,1.5.1.9 ko:K00290,ko:K14157 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R00716,R02313 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 Bacteria 1IWHP@117747,4NF46@976,COG0686@1,COG0686@2 NA|NA|NA E Alanine dehydrogenase/PNT, N-terminal domain MAG.T22.56_01416 1453498.LG45_09625 5.2e-128 464.2 Flavobacterium yneE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08994 ko00000,ko02000 1.A.46.2 Bacteria 1HYG9@117743,2NVTB@237,4NGJ0@976,COG3781@1,COG3781@2 NA|NA|NA S Bestrophin, RFP-TM, chloride channel MAG.T22.56_01417 1123248.KB893386_gene1980 2.5e-76 292.4 Sphingobacteriia yfcH ko:K07071 ko00000 Bacteria 1IQB7@117747,4NINM@976,COG1090@1,COG1090@2 NA|NA|NA S PFAM NAD dependent epimerase dehydratase family MAG.T22.56_01419 700598.Niako_1147 5.6e-127 461.1 Sphingobacteriia ko:K07098 ko00000 Bacteria 1IPSC@117747,4NFCH@976,COG1408@1,COG1408@2 NA|NA|NA S DNA mismatch repair protein MutT MAG.T22.56_01420 700598.Niako_1146 7.1e-41 173.7 Sphingobacteriia Bacteria 1IRZM@117747,4NQV9@976,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase MAG.T22.56_01421 1536772.R70723_07490 4.5e-07 62.4 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis MAG.T22.56_01422 1121889.AUDM01000017_gene2155 1.4e-28 131.7 Flavobacterium ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1I408@117743,2NX67@237,4NSRJ@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T22.56_01423 869213.JCM21142_73029 9.2e-24 115.9 Cytophagia Bacteria 3320J@2,47RW3@768503,4NV34@976,arCOG08720@1 NA|NA|NA S Domain of unknown function (DUF2024) MAG.T22.56_01424 1041826.FCOL_01805 5.8e-70 270.8 Flavobacterium yggS ko:K06997 ko00000 Bacteria 1HZ24@117743,2NT6J@237,4NE42@976,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MAG.T22.56_01425 1408473.JHXO01000008_gene2851 1.8e-63 249.2 Bacteroidia 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2FS4D@200643,4NMFC@976,COG0518@1,COG0518@2 NA|NA|NA F Glutamine amidotransferase class-I MAG.T22.56_01426 743722.Sph21_2247 6.1e-134 484.2 Sphingobacteriia ko:K03294 ko00000 2.A.3.2 Bacteria 1IPW4@117747,4NH7J@976,COG0531@1,COG0531@2 NA|NA|NA E amino acid MAG.T22.56_01427 700598.Niako_4928 8e-92 344.0 Sphingobacteriia rfaE 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IQQ3@117747,4NHUV@976,COG2870@1,COG2870@2 NA|NA|NA M Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose MAG.T22.56_01428 714943.Mucpa_3534 2.2e-211 742.3 Sphingobacteriia recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1IQU0@117747,4NG10@976,COG0514@1,COG0514@2 NA|NA|NA L RQC MAG.T22.56_01429 485918.Cpin_1029 5.5e-217 760.4 Sphingobacteriia Bacteria 1IVSR@117747,4PKQG@976,COG0318@1,COG0318@2 NA|NA|NA IQ GH3 auxin-responsive promoter MAG.T22.56_01430 470145.BACCOP_02209 1.3e-51 209.1 Bacteroidaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2FR7A@200643,4AP3D@815,4NNI4@976,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA MAG.T22.56_01431 153721.MYP_977 5.4e-104 384.4 Cytophagia rffH 2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8 ko:K00973,ko:K04042,ko:K16881 ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130 M00114,M00362,M00793 R00416,R00885,R01818,R02328,R05332 RC00002,RC00004,RC00166,RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 47ND5@768503,4NE97@976,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase MAG.T22.56_01432 485918.Cpin_1186 1e-70 274.6 Sphingobacteriia Bacteria 1IR0N@117747,4NDVW@976,COG0457@1,COG0457@2 NA|NA|NA S PFAM Tetratricopeptide MAG.T22.56_01433 700598.Niako_6998 3.2e-20 105.9 Sphingobacteriia Bacteria 1ITXE@117747,4NFYQ@976,COG2834@1,COG2834@2 NA|NA|NA M Domain of unknown function (DUF4292) MAG.T22.56_01434 1123371.ATXH01000036_gene1572 9.2e-96 356.7 Thermodesulfobacteria rfbF 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 R00956 RC00002 ko00000,ko00001,ko01000 Bacteria 2GHN7@200940,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase MAG.T22.56_01436 926549.KI421517_gene3605 7.5e-53 215.7 Cytophagia ladS ko:K20971 ko02025,map02025 ko00000,ko00001,ko01001,ko02022 Bacteria 47KZN@768503,4NI29@976,COG0457@1,COG0457@2,COG4251@1,COG4251@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.56_01446 509635.N824_00975 2.8e-08 67.0 Sphingobacteriia Bacteria 1IUJX@117747,2ZXVP@2,4NNWP@976,arCOG06169@1 NA|NA|NA S Arylsulfotransferase (ASST) MAG.T22.56_01447 1229487.AMYW01000020_gene2547 1.4e-62 246.1 Flavobacterium petA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009512,GO:0009579,GO:0016491,GO:0016667,GO:0016669,GO:0032991,GO:0044424,GO:0044436,GO:0044464,GO:0050338,GO:0055114,GO:0070069 1.8.2.2 ko:K02634,ko:K19713 ko00195,ko01100,map00195,map01100 M00162 ko00000,ko00001,ko00002,ko00194,ko01000 Bacteria 1HZDH@117743,2NVMW@237,4NGIH@976,COG3258@1,COG3258@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III MAG.T22.56_01448 1123248.KB893314_gene3577 8.1e-137 494.2 Sphingobacteriia Bacteria 1IQA3@117747,2DBCF@1,2Z8DB@2,4NG6B@976 NA|NA|NA MAG.T22.56_01449 485918.Cpin_7096 1.8e-184 652.1 Sphingobacteriia pyrC 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQSD@117747,4NE3T@976,COG0044@1,COG0044@2 NA|NA|NA F Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides MAG.T22.56_01450 700598.Niako_5550 3.1e-83 315.8 Sphingobacteriia mutS ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1IPHP@117747,4NEXA@976,COG0249@1,COG0249@2 NA|NA|NA L DNA mismatch repair protein MutS MAG.T22.56_01451 485918.Cpin_0861 6.7e-74 284.3 Sphingobacteriia 3.4.21.105 ko:K09650 ko00000,ko01000,ko01002,ko03029 Bacteria 1IS1R@117747,4NIYR@976,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family MAG.T22.56_01452 1123248.KB893331_gene3772 3.5e-30 139.0 Sphingobacteriia Bacteria 1IS2B@117747,4NGVJ@976,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family MAG.T22.56_01453 1408473.JHXO01000010_gene3598 1.7e-37 163.7 Bacteroidia Bacteria 2FNIX@200643,4NGUV@976,COG3568@1,COG3568@2 NA|NA|NA S endonuclease exonuclease phosphatase family protein MAG.T22.56_01454 485918.Cpin_7286 2.6e-13 82.0 Sphingobacteriia Bacteria 1IUP5@117747,2AFPJ@1,315RB@2,4PJWT@976 NA|NA|NA S Sporulation related domain MAG.T22.56_01455 485918.Cpin_7287 3.3e-129 468.4 Sphingobacteriia ko:K01436,ko:K12941 ko00000,ko01000,ko01002 Bacteria 1INTB@117747,4NGBI@976,COG1473@1,COG1473@2 NA|NA|NA S amidohydrolase MAG.T22.56_01456 485918.Cpin_1861 4.1e-84 318.5 Sphingobacteriia cfa3 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IPY4@117747,4NE8K@976,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T22.56_01457 929713.NIASO_13530 8.7e-40 169.9 Sphingobacteriia fcbC ko:K07107 ko00000,ko01000 Bacteria 1ITSJ@117747,4NRHH@976,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T22.56_01458 153721.MYP_190 3.8e-31 141.7 Cytophagia Bacteria 2E7GE@1,331Z7@2,47RY7@768503,4NWN3@976 NA|NA|NA MAG.T22.56_01459 1122605.KB893647_gene250 8e-30 136.7 Sphingobacteriia fabZ2 Bacteria 1IU4J@117747,4NSB5@976,COG4706@1,COG4706@2 NA|NA|NA I dehydratase MAG.T22.56_01460 485918.Cpin_1857 1.6e-80 306.2 Sphingobacteriia ycdQ Bacteria 1IT2S@117747,4NF49@976,COG4261@1,COG4261@2 NA|NA|NA S Bacterial lipid A biosynthesis acyltransferase MAG.T22.56_01461 485918.Cpin_1856 1.7e-22 111.7 Sphingobacteriia acpP_2 ko:K02078 ko00000,ko00001 Bacteria 1ITYS@117747,4NV57@976,COG0236@1,COG0236@2 NA|NA|NA IQ Phosphopantetheine attachment site MAG.T22.56_01462 929713.NIASO_13180 7.2e-24 116.3 Sphingobacteriia Bacteria 1ITNM@117747,2E46C@1,335XM@2,4NX4H@976 NA|NA|NA MAG.T22.56_01463 1121481.AUAS01000006_gene650 1.5e-13 83.2 Cytophagia Bacteria 29TMV@1,30EVG@2,47RB5@768503,4NNPM@976 NA|NA|NA MAG.T22.56_01464 1123278.KB893522_gene2524 1.9e-152 546.6 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47JDS@768503,4PKF2@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug MAG.T22.56_01465 1121373.KB903654_gene1493 2.7e-40 172.6 Cytophagia Bacteria 28IS5@1,2Z8RB@2,47R7X@768503,4NIIH@976 NA|NA|NA MAG.T22.56_01466 700598.Niako_5586 1.2e-120 439.5 Sphingobacteriia fadA 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 Bacteria 1INYF@117747,4NE3Q@976,COG0183@1,COG0183@2 NA|NA|NA I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation MAG.T22.56_01467 925409.KI911562_gene2070 7.5e-27 127.5 Sphingobacteriia acpT GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006553,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0019878,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.8.7 ko:K00997,ko:K06133 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_3584 Bacteria 1ITW4@117747,4NSBI@976,COG2091@1,COG2091@2 NA|NA|NA H Belongs to the P-Pant transferase superfamily MAG.T22.56_01468 485918.Cpin_1662 0.0 1127.5 Sphingobacteriia glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1INRQ@117747,4NG2B@976,COG3968@1,COG3968@2 NA|NA|NA S glutamine synthetase MAG.T22.56_01469 1123277.KB893206_gene3333 7.5e-45 187.2 Cytophagia 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 47RI6@768503,4NPIE@976,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain MAG.T22.56_01471 925409.KI911562_gene2475 1.7e-52 212.2 Sphingobacteriia ymaD Bacteria 1ISAI@117747,4NNF7@976,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein MAG.T22.56_01472 509635.N824_26125 2e-60 239.2 Sphingobacteriia blm GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0008270,GO:0008800,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0016999,GO:0017001,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046872,GO:0046914 3.5.2.6 ko:K17837 ko01501,map01501 R06363 RC01499 ko00000,ko00001,ko01000 Bacteria 1IS3P@117747,4NPPW@976,COG0491@1,COG0491@2 NA|NA|NA E Metallo-beta-lactamase superfamily MAG.T22.56_01473 929556.Solca_2021 2.4e-111 408.3 Sphingobacteriia scoA 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 1IQP0@117747,4NF3T@976,COG1788@1,COG1788@2 NA|NA|NA I PFAM Coenzyme A transferase MAG.T22.56_01474 1123248.KB893370_gene5070 2.3e-100 371.7 Sphingobacteriia scoB 2.8.3.5 ko:K01027,ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 1IQBC@117747,4NG9J@976,COG2057@1,COG2057@2 NA|NA|NA I PFAM Coenzyme A transferase MAG.T22.56_01475 1454007.JAUG01000060_gene784 1.4e-21 109.0 Sphingobacteriia arsC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 ko00000,ko01000 Bacteria 1IU09@117747,4NSA6@976,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family MAG.T22.56_01477 700598.Niako_2922 2.7e-192 678.3 Sphingobacteriia chlI 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 R03877 RC01012 ko00000,ko00001,ko01000 iNJ661.Rv0958 Bacteria 1IQK5@117747,4NF1J@976,COG1239@1,COG1239@2 NA|NA|NA H Sigma-54 interaction domain MAG.T22.56_01479 1218108.KB908298_gene3447 3.2e-28 131.3 Flavobacteriia yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 ko:K15034 ko00000,ko03012 Bacteria 1I3Z8@117743,4NQ41@976,COG1186@1,COG1186@2 NA|NA|NA J chain release factor MAG.T22.56_01480 700598.Niako_0184 2.7e-288 997.7 Sphingobacteriia bfmBAB 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IV4C@117747,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type MAG.T22.56_01481 929713.NIASO_09530 2.2e-64 252.3 Bacteroidetes sanA Bacteria 4NNUT@976,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain MAG.T22.56_01482 485918.Cpin_1900 0.0 1167.9 Sphingobacteriia mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1IR7Y@117747,4NEGB@976,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity MAG.T22.56_01483 1122605.KB893637_gene3106 5.6e-151 541.2 Bacteroidetes Bacteria 4NGUB@976,COG0308@1,COG0308@2 NA|NA|NA E peptidase M1 MAG.T22.56_01484 1185876.BN8_05462 1.7e-46 193.4 Cytophagia Bacteria 47KIJ@768503,4NDW4@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.56_01485 1166018.FAES_1220 1e-45 190.7 Cytophagia Bacteria 47KIJ@768503,4NDW4@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.56_01486 1166018.FAES_1220 1.7e-41 176.4 Cytophagia Bacteria 47KIJ@768503,4NDW4@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.56_01487 1178825.ALIH01000014_gene1979 1.3e-06 60.5 Flavobacteriia Bacteria 1I0JW@117743,2DBVI@1,2ZBB6@2,4NE5V@976 NA|NA|NA MAG.T22.56_01488 485918.Cpin_1058 4.5e-156 558.1 Sphingobacteriia prc 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1IQA9@117747,4NDWU@976,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T22.56_01489 1123248.KB893323_gene1608 1.6e-08 65.9 Bacteroidetes Bacteria 4PKV1@976,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase MAG.T22.56_01490 1317122.ATO12_04435 4.1e-13 80.9 Flavobacteriia Bacteria 1I551@117743,2E372@1,32Y6U@2,4NUUI@976 NA|NA|NA S Protein of unknown function (DUF2752) MAG.T22.56_01491 1392490.JHZX01000001_gene3093 1.7e-23 115.5 Flavobacteriia Bacteria 1I49R@117743,2DMKZ@1,32SAQ@2,4NS7K@976 NA|NA|NA MAG.T22.56_01492 1267211.KI669560_gene98 1.6e-37 163.3 Bacteria Bacteria 28NPZ@1,2ZBPQ@2 NA|NA|NA MAG.T22.56_01494 700598.Niako_6667 3.1e-41 174.9 Bacteroidetes ko:K03088 ko00000,ko03021 Bacteria 4NQ7S@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.56_01495 485918.Cpin_1203 2.3e-85 323.2 Sphingobacteriia rluB 5.4.99.19,5.4.99.20,5.4.99.22 ko:K06178,ko:K06181,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1INNI@117747,4NEE1@976,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T22.56_01496 700598.Niako_5743 2.2e-85 322.8 Sphingobacteriia ssnA 3.5.4.40 ko:K20810 ko00130,ko01110,map00130,map01110 R10695 RC00477 ko00000,ko00001,ko01000 Bacteria 1IPAQ@117747,4NJVU@976,COG0402@1,COG0402@2 NA|NA|NA F amidohydrolase MAG.T22.56_01498 1121373.KB903626_gene3247 1e-68 267.3 Cytophagia Bacteria 2EEY9@1,338RN@2,47SKR@768503,4NVB1@976 NA|NA|NA MAG.T22.56_01499 762903.Pedsa_3038 1.1e-50 206.8 Sphingobacteriia Bacteria 1J0Y7@117747,4PM2J@976,COG5373@1,COG5373@2 NA|NA|NA S membrane MAG.T22.56_01501 1123248.KB893315_gene3142 2.7e-92 345.1 Sphingobacteriia Bacteria 1IR78@117747,4NFJ5@976,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate nucleotide phosphotransferase, PPK2 family MAG.T22.56_01502 1237149.C900_03519 4.3e-54 218.4 Bacteroidetes 3.1.1.24 ko:K01055,ko:K02014 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.14 Bacteria 4PNDE@976,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.56_01503 880071.Fleli_1811 7.8e-106 390.6 Cytophagia phaC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 ko:K03821 ko00650,map00650 R04254 RC00004 ko00000,ko00001,ko01000 iJN678.phbC Bacteria 47TSY@768503,4P0GQ@976,COG3243@1,COG3243@2 NA|NA|NA I PHB de-polymerase C-terminus MAG.T22.56_01505 700598.Niako_5597 9.1e-46 189.5 Sphingobacteriia rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ITCV@117747,4NNPW@976,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site MAG.T22.56_01506 1123248.KB893323_gene1626 1.1e-97 362.8 Sphingobacteriia trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1IQ54@117747,4NF2Q@976,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family MAG.T22.56_01507 700598.Niako_7036 5.6e-25 120.9 Sphingobacteriia rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1ISWU@117747,4NQF0@976,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes MAG.T22.56_01509 485918.Cpin_6897 3.8e-162 578.2 Sphingobacteriia ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 1IVUK@117747,4NK5Q@976,COG2317@1,COG2317@2 NA|NA|NA E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues MAG.T22.56_01510 485918.Cpin_7051 1.1e-201 709.5 Sphingobacteriia relA 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 1IQ2F@117747,4NESY@976,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance MAG.T22.56_01511 1408433.JHXV01000012_gene3975 9.2e-08 64.7 Cryomorphaceae Bacteria 1IG1J@117743,2ABBW@1,2PBZZ@246874,310SM@2,4PFE8@976 NA|NA|NA MAG.T22.56_01512 925409.KI911562_gene2583 6.2e-49 201.1 Sphingobacteriia ykfC 3.4.14.13 ko:K20742,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1IRW3@117747,4NE2T@976,COG0791@1,COG0791@2 NA|NA|NA M PFAM NlpC P60 family MAG.T22.56_01513 485918.Cpin_7243 1.8e-207 728.8 Sphingobacteriia rny ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1IQZ1@117747,4NE3V@976,COG1418@1,COG1418@2 NA|NA|NA M Endoribonuclease that initiates mRNA decay MAG.T22.56_01514 1123248.KB893359_gene2047 5.5e-142 510.8 Sphingobacteriia romA Bacteria 1IQQV@117747,4NENZ@976,COG2220@1,COG2220@2 NA|NA|NA S beta-lactamase MAG.T22.56_01515 208439.AJAP_25800 6.6e-92 344.0 Pseudonocardiales yneD Bacteria 2GRRV@201174,4EDSG@85010,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase MAG.T22.56_01516 760192.Halhy_5203 4.6e-49 201.1 Sphingobacteriia Bacteria 1ITM5@117747,4NFR4@976,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.56_01517 1380600.AUYN01000009_gene1700 1.1e-21 110.5 Flavobacteriia Bacteria 1HZSG@117743,2B5D2@1,31Y78@2,4NHI5@976 NA|NA|NA MAG.T22.56_01518 929713.NIASO_13295 3.5e-140 505.0 Sphingobacteriia paaK 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1IP0X@117747,4NGRR@976,COG1541@1,COG1541@2 NA|NA|NA H AMP-binding enzyme MAG.T22.56_01519 1267211.KI669560_gene2672 3.7e-202 711.1 Sphingobacteriia guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1IPBW@117747,4NDXQ@976,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth MAG.T22.56_01520 485918.Cpin_3751 6.7e-47 193.7 Sphingobacteriia Bacteria 1IQ1K@117747,4NFMQ@976,COG1680@1,COG1680@2 NA|NA|NA V beta-lactamase MAG.T22.56_01521 929556.Solca_3278 4.5e-80 304.3 Sphingobacteriia pyc GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18410 Bacteria 1IQ37@117747,4NFHU@976,COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second MAG.T22.56_01522 1123278.KB893542_gene5506 1.3e-149 536.2 Cytophagia ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 47KQ3@768503,4NDUX@976,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T22.56_01523 485918.Cpin_0364 9.9e-69 267.3 Sphingobacteriia ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1IQN0@117747,4NERP@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.56_01524 485918.Cpin_6294 6.4e-42 178.3 Sphingobacteriia Bacteria 1ISCP@117747,28HHD@1,2Z7T3@2,4NGWB@976 NA|NA|NA S Protein of unknown function (DUF3810) MAG.T22.56_01525 485918.Cpin_6260 1.2e-232 812.4 Sphingobacteriia bhbA 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPCT@117747,4PN0H@976,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase MAG.T22.56_01526 1124780.ANNU01000030_gene1166 3.5e-25 121.7 Cytophagia Bacteria 28NWP@1,2ZBUH@2,47M02@768503,4NNPT@976 NA|NA|NA MAG.T22.56_01527 1356852.N008_01175 9e-97 360.1 Cytophagia 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 47PF7@768503,4NF6D@976,COG2227@1,COG2227@2 NA|NA|NA H ubiE/COQ5 methyltransferase family MAG.T22.56_01528 700598.Niako_5071 7.3e-296 1023.1 Sphingobacteriia lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1INS9@117747,4NGQ0@976,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase MAG.T22.56_01529 1279009.ADICEAN_03932 4.7e-18 98.2 Cytophagia ko:K06142 ko00000 Bacteria 47MRT@768503,4NQGG@976,COG2825@1,COG2825@2 NA|NA|NA M PFAM Outer membrane chaperone Skp (OmpH) MAG.T22.56_01530 485918.Cpin_1429 1e-38 167.2 Sphingobacteriia tonB ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1ISCX@117747,4NFH6@976,COG0810@1,COG0810@2 NA|NA|NA U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.56_01531 485918.Cpin_1428 1.1e-45 189.9 Sphingobacteriia exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 1ITNF@117747,4NMQ8@976,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR MAG.T22.56_01532 485918.Cpin_1427 3.3e-54 218.4 Sphingobacteriia exbD1 Bacteria 1IRXT@117747,4NMT4@976,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR MAG.T22.56_01533 485918.Cpin_1426 1.1e-83 316.6 Sphingobacteriia exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 1INP5@117747,4NE8M@976,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel MAG.T22.56_01534 319236.JCM19294_199 1.5e-68 265.8 Nonlabens ppa 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1HX3R@117743,3HJJI@363408,4NGBU@976,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions MAG.T22.56_01535 1123248.KB893317_gene4379 3.7e-161 574.7 Sphingobacteriia yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 1INX9@117747,4NEKI@976,COG2270@1,COG2270@2 NA|NA|NA S COGs COG2270 Permease of the major facilitator superfamily MAG.T22.56_01536 700598.Niako_6934 9.2e-102 376.7 Sphingobacteriia ytnP Bacteria 1INUA@117747,4NE98@976,COG0491@1,COG0491@2 NA|NA|NA S beta-lactamase MAG.T22.56_01537 1137281.D778_02364 7.1e-10 71.2 Flavobacteriia Bacteria 1HZ4C@117743,28MKG@1,2ZAWQ@2,4NIYN@976 NA|NA|NA MAG.T22.56_01538 999550.KI421507_gene1184 3.1e-22 112.5 Alphaproteobacteria Bacteria 1R6Z5@1224,2U3VI@28211,COG2520@1,COG2520@2 NA|NA|NA J Methyltransferase FkbM family MAG.T22.56_01539 1123248.KB893319_gene4004 5.9e-26 122.9 Sphingobacteriia Bacteria 1IZGJ@117747,2BZQY@1,2ZVH4@2,4P73I@976 NA|NA|NA MAG.T22.56_01540 1267211.KI669560_gene2082 1.7e-98 366.3 Bacteria tolB ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T22.56_01541 485918.Cpin_5958 6.4e-62 243.8 Sphingobacteriia sua5 2.7.7.87,3.5.2.3 ko:K01465,ko:K07566 ko00240,ko01100,map00240,map01100 M00051 R01993,R10463 RC00632,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 Bacteria 1IRXH@117747,4NM43@976,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family MAG.T22.56_01542 1227739.Hsw_1483 3e-28 131.7 Cytophagia Bacteria 2CG1Y@1,31NHZ@2,47QC0@768503,4NQ9Z@976 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T22.56_01543 929556.Solca_2632 2.8e-22 111.7 Sphingobacteriia Bacteria 1ITEJ@117747,2CG1Y@1,31NHZ@2,4NQ9Z@976 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T22.56_01544 700598.Niako_0287 4.5e-174 617.5 Sphingobacteriia aspC 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS10450 Bacteria 1IPSR@117747,4NG6G@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.56_01545 485918.Cpin_1198 2.1e-190 672.2 Sphingobacteriia ade GO:0000034,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0006040,GO:0006044,GO:0006046,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008448,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016787,GO:0016810,GO:0016811,GO:0016814,GO:0018130,GO:0019213,GO:0019239,GO:0019438,GO:0019439,GO:0030145,GO:0034641,GO:0042221,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046348,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070887,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0097237,GO:0098754,GO:0098869,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1990748 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 R01244 RC00477 ko00000,ko00001,ko01000 iECUMN_1333.ECUMN_4192,iSFV_1184.SFV_3844,iYO844.BSU14520 Bacteria 1IQD0@117747,4NFD9@976,COG1001@1,COG1001@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family MAG.T22.56_01546 992406.RIA_1414 1.5e-28 132.5 Flavobacteriia ctb ko:K06886 ko00000 Bacteria 1I3FR@117743,4NRK9@976,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin MAG.T22.56_01547 1123277.KB893174_gene5927 7.8e-37 162.9 Cytophagia Bacteria 47XEG@768503,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2 NA|NA|NA T Histidine kinase MAG.T22.56_01548 1223410.KN050846_gene173 4.8e-41 174.9 Flavobacteriia ko:K02477 ko00000,ko02022 Bacteria 1HZ0B@117743,4NEXZ@976,COG3279@1,COG3279@2 NA|NA|NA T COG3279 Response regulator of the LytR AlgR family MAG.T22.56_01549 925409.KI911562_gene885 1.1e-46 193.4 Sphingobacteriia lutC ko:K00782 ko00000 Bacteria 1IRJ2@117747,4NIGX@976,COG1556@1,COG1556@2 NA|NA|NA S PFAM Uncharacterised ACR, YkgG family COG1556 MAG.T22.56_01550 762903.Pedsa_2739 1.7e-62 246.9 Sphingobacteriia ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1IQF2@117747,4NI7Q@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.56_01551 411476.BACOVA_01583 2e-105 389.0 Bacteroidaceae glk 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2FNGN@200643,4AMRT@815,4NFZ1@976,COG1940@1,COG1940@2 NA|NA|NA GK Psort location Cytoplasmic, score 9.26 MAG.T22.56_01552 865937.Gilli_2079 1.9e-122 446.0 Gillisia Bacteria 1HY8N@117743,2P5TK@244698,4NEYR@976,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily MAG.T22.56_01554 1123248.KB893315_gene3145 5.4e-189 667.2 Sphingobacteriia gcdH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 Bacteria 1INZ7@117747,4NEKJ@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.56_01555 929713.NIASO_06540 2.4e-137 495.0 Sphingobacteriia rpoD ko:K03086 ko00000,ko03021 Bacteria 1INNM@117747,4NEBF@976,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T22.56_01557 700598.Niako_3976 1.1e-33 149.8 Sphingobacteriia rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1ISE3@117747,4NMFP@976,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA MAG.T22.56_01558 1163408.UU9_01024 5.4e-51 207.6 Xanthomonadales Bacteria 1RB4A@1224,1S2UY@1236,1X43K@135614,COG0705@1,COG0705@2 NA|NA|NA S membrane protein (homolog of Drosophila rhomboid) MAG.T22.56_01559 485918.Cpin_3762 4.3e-109 401.7 Sphingobacteriia tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1IQ7X@117747,4NEJS@976,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine MAG.T22.56_01560 925409.KI911562_gene1988 3.3e-28 131.0 Sphingobacteriia Bacteria 1J0N6@117747,4PKQM@976,COG3063@1,COG3063@2 NA|NA|NA NU Type IV pilus biogenesis stability protein PilW MAG.T22.56_01562 468059.AUHA01000003_gene1569 2.3e-13 81.3 Sphingobacteriia cusB ko:K13888,ko:K18990 M00709,M00720 ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 Bacteria 1IP8S@117747,4NERP@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.56_01563 509635.N824_13300 0.0 1318.5 Sphingobacteriia acrD ko:K18989 M00720 ko00000,ko00002,ko02000 2.A.6.2.30 Bacteria 1IQYT@117747,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.56_01564 153721.MYP_3446 4e-110 404.8 Bacteroidetes crtF Bacteria 4NGN8@976,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase MAG.T22.56_01565 485918.Cpin_1863 5.5e-151 540.8 Sphingobacteriia fixC Bacteria 1INQ3@117747,4NEI6@976,COG0644@1,COG0644@2 NA|NA|NA C Tryptophan halogenase MAG.T22.56_01566 714943.Mucpa_6802 6.3e-31 141.0 Sphingobacteriia Bacteria 1ITHW@117747,4NMSI@976,COG0304@1,COG0304@2 NA|NA|NA IQ 3-oxoacyl-ACP synthase MAG.T22.56_01567 714943.Mucpa_6801 7.2e-124 450.7 Sphingobacteriia fabF-1 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458,ko:K11054 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IRGP@117747,4NFC8@976,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T22.56_01568 485918.Cpin_1867 1.3e-60 240.4 Sphingobacteriia Bacteria 1ISE9@117747,4NEU6@976,COG0304@1,COG0304@2 NA|NA|NA IQ Beta-ketoacyl synthase, N-terminal domain MAG.T22.56_01569 925409.KI911562_gene1310 3.6e-86 324.7 Sphingobacteriia poxF 1.17.1.1 ko:K00523 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000 Bacteria 1IXDV@117747,4PN6Y@976,COG1018@1,COG1018@2 NA|NA|NA C Oxidoreductase FAD-binding domain MAG.T22.56_01570 485918.Cpin_1933 2.1e-11 75.9 Bacteria Bacteria COG1629@1,COG1629@2 NA|NA|NA P transport MAG.T22.56_01571 485918.Cpin_1217 6.7e-267 926.4 Sphingobacteriia aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN678.aspS,iSFV_1184.SFV_1868 Bacteria 1IR7B@117747,4NECY@976,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) MAG.T22.56_01573 700598.Niako_5264 1.1e-52 214.5 Sphingobacteriia Bacteria 1IPSE@117747,4NE8J@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.56_01574 1122605.KB893637_gene3108 3.3e-180 637.9 Sphingobacteriia sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ0Q@117747,4NFHA@976,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit MAG.T22.56_01575 929556.Solca_1401 2.7e-83 315.5 Sphingobacteriia Bacteria 1IP8N@117747,4NHAD@976,COG1801@1,COG1801@2 NA|NA|NA S Protein of unknown function DUF72 MAG.T22.56_01576 1042376.AFPK01000039_gene1990 2e-10 72.0 Flavobacteriia Bacteria 1I25X@117743,2APBA@1,31EDH@2,4NPIT@976 NA|NA|NA S Putative prokaryotic signal transducing protein MAG.T22.56_01577 172045.KS04_01985 2.6e-26 124.8 Flavobacteriia ko:K07343 ko00000 Bacteria 1I4CE@117743,4NSGZ@976,COG3070@1,COG3070@2 NA|NA|NA K TfoX N-terminal domain MAG.T22.56_01578 313603.FB2170_10259 1.1e-08 67.0 Flavobacteriia Bacteria 1I8FX@117743,2ETC6@1,33KW3@2,4P061@976 NA|NA|NA MAG.T22.56_01579 526222.Desal_2107 1.8e-54 219.5 Bacteria Bacteria 2FABJ@1,342K4@2 NA|NA|NA MAG.T22.56_01581 925409.KI911562_gene22 2.6e-70 271.6 Sphingobacteriia pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IPGS@117747,4NFW2@976,COG0126@1,COG0126@2 NA|NA|NA G Belongs to the phosphoglycerate kinase family MAG.T22.56_01583 1123276.KB893245_gene1003 1.1e-78 300.8 Cytophagia 3.6.4.12 ko:K17680 ko00000,ko01000,ko03029 Bacteria 47NER@768503,4NETK@976,COG0358@1,COG0358@2 NA|NA|NA L Protein of unknown function (DUF3987) MAG.T22.56_01584 1122605.KB893649_gene3840 1.1e-69 269.2 Sphingobacteriia rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IRUT@117747,4NM60@976,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors MAG.T22.56_01585 700598.Niako_4938 1.1e-103 382.9 Sphingobacteriia rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IPE4@117747,4NEIC@976,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release MAG.T22.56_01586 925409.KI911562_gene2820 7.4e-66 256.9 Sphingobacteriia rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IS1J@117747,4NFFK@976,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors MAG.T22.56_01587 485918.Cpin_1709 1.8e-36 158.7 Bacteroidetes rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 4NQAQ@976,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation MAG.T22.56_01588 1313421.JHBV01000041_gene3473 7.7e-10 70.5 Bacteroidetes Bacteria 29S5K@1,30DA3@2,4NP0H@976 NA|NA|NA MAG.T22.56_01589 1239415.CM001837_gene332 1.1e-79 303.1 Dokdonia aqpZ ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 1HXX1@117743,37FP6@326319,4NFW4@976,COG0580@1,COG0580@2 NA|NA|NA G Major intrinsic protein MAG.T22.56_01590 485918.Cpin_7300 6.8e-191 673.7 Sphingobacteriia IV02_08645 ko:K07137 ko00000 Bacteria 1IQIE@117747,4NEUQ@976,COG2509@1,COG2509@2 NA|NA|NA S FAD-dependent dehydrogenase MAG.T22.56_01591 929713.NIASO_07775 2.1e-174 619.4 Sphingobacteriia dsbD 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 1IQXN@117747,4NEW6@976,COG4232@1,COG4232@2 NA|NA|NA CO Cytochrome c biogenesis protein transmembrane region MAG.T22.56_01592 929713.NIASO_11345 4.7e-91 340.9 Sphingobacteriia purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1IRA4@117747,4NFER@976,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.56_01593 926549.KI421517_gene1707 3.7e-87 328.2 Cytophagia 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 47JSF@768503,4NFQ3@976,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T22.56_01594 1122605.KB893647_gene420 6e-105 387.9 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_01595 926549.KI421517_gene838 2.8e-113 415.2 Cytophagia wbpP 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 47M4Q@768503,4NEKA@976,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.56_01597 485918.Cpin_0888 3.8e-31 140.6 Sphingobacteriia hupB ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1IYVW@117747,4NSK6@976,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions MAG.T22.56_01598 485918.Cpin_0889 2e-30 138.3 Sphingobacteriia Bacteria 1IU5M@117747,2C9BK@1,32RP1@2,4NSPA@976 NA|NA|NA S Domain of unknown function (DUF4286) MAG.T22.56_01599 1123248.KB893386_gene1984 1.5e-100 372.9 Sphingobacteriia rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1IQE6@117747,4NE5H@976,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit MAG.T22.56_01600 485918.Cpin_7003 1.4e-93 350.1 Sphingobacteriia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IR3W@117747,4NEBD@976,COG0577@1,COG0577@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, permease component MAG.T22.56_01601 926562.Oweho_2578 4.2e-94 352.4 Cryomorphaceae fitD ko:K19615 ko02020,map02020 ko00000,ko00001,ko02042 Bacteria 1I8WB@117743,2PBTD@246874,4P2B3@976,COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T22.56_01602 1123248.KB893314_gene3638 4.5e-107 394.4 Sphingobacteriia atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 1IQEQ@117747,4NECM@976,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex MAG.T22.56_01603 1313421.JHBV01000008_gene4315 9.4e-08 64.3 Bacteria Bacteria COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity MAG.T22.56_01604 1123277.KB893186_gene5428 1.1e-29 137.9 Cytophagia Bacteria 47KYM@768503,4NJQV@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.56_01605 760192.Halhy_1397 3.9e-84 318.5 Sphingobacteriia Bacteria 1ISHH@117747,4NITE@976,COG0845@1,COG0845@2 NA|NA|NA M SPTR Efflux transporter, RND family, MFP subunit MAG.T22.56_01606 760192.Halhy_1396 3.1e-133 481.9 Sphingobacteriia lolC ko:K09808 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125 Bacteria 1IRPD@117747,4NHBR@976,COG4591@1,COG4591@2 NA|NA|NA M COGs COG4591 ABC-type transport system involved in lipoprotein release permease component MAG.T22.56_01607 761193.Runsl_1629 2.6e-89 335.1 Cytophagia lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 47KXC@768503,4NFCG@976,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of MAG.T22.56_01608 760192.Halhy_1394 1.5e-75 290.0 Sphingobacteriia Bacteria 1ISFM@117747,4NFDP@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.56_01609 760192.Halhy_1393 4.1e-80 304.7 Bacteroidetes lytT ko:K02477,ko:K07705,ko:K11641 ko02020,map02020 M00492,M00494 ko00000,ko00001,ko00002,ko02022 Bacteria 4NHDT@976,COG3279@1,COG3279@2 NA|NA|NA T Two component transcriptional regulator, lyttr family MAG.T22.56_01610 643867.Ftrac_2367 1.7e-45 189.9 Cytophagia 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 47XAU@768503,4PNPN@976,COG0596@1,COG0596@2 NA|NA|NA S Ndr family MAG.T22.56_01611 1121904.ARBP01000002_gene6780 1.3e-17 98.2 Bacteroidetes Bacteria 4NGV7@976,COG3291@1,COG3291@2,COG4733@1,COG4733@2 NA|NA|NA L PKD domain protein MAG.T22.56_01612 929556.Solca_2447 4e-15 88.2 Sphingobacteriia Bacteria 1ISFV@117747,2CI1G@1,2Z7JA@2,4NF1T@976 NA|NA|NA S Domain of unknown function (DUF4294) MAG.T22.56_01617 485918.Cpin_5705 1.2e-47 196.1 Sphingobacteriia purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iJN678.purE,iNJ661.Rv3275c Bacteria 1IRVT@117747,4NME9@976,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T22.56_01618 485918.Cpin_5706 8.4e-122 443.7 Sphingobacteriia purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 1IQSA@117747,4NEGE@976,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) MAG.T22.56_01619 686340.Metal_0288 1.7e-68 266.2 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator MAG.T22.56_01620 1123248.KB893337_gene2381 1.6e-98 366.7 Sphingobacteriia Bacteria 1IRU6@117747,4NEH3@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.56_01621 468059.AUHA01000002_gene1345 2.8e-137 495.4 Sphingobacteriia ko:K03543 M00701 ko00000,ko00002,ko02000 8.A.1.1 Bacteria 1J0IM@117747,4PM5Z@976,COG1566@1,COG1566@2 NA|NA|NA V Biotin-lipoyl like MAG.T22.56_01622 468059.AUHA01000002_gene1344 2.9e-155 555.4 Sphingobacteriia ko:K02021 ko00000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 1IQD5@117747,4NFJF@976,COG2274@1,COG2274@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.56_01625 45351.EDO26887 3.3e-77 295.0 Metazoa 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Metazoa 38ETQ@33154,3B9YV@33208,COG0149@1,KOG1643@2759 NA|NA|NA G triose-phosphate isomerase activity MAG.T22.56_01627 1123248.KB893370_gene4996 1.1e-45 189.5 Sphingobacteriia elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1ITI2@117747,4NQPR@976,COG2153@1,COG2153@2 NA|NA|NA S Gnat family MAG.T22.56_01628 485917.Phep_2526 1.3e-167 596.7 Sphingobacteriia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1INSR@117747,4NHH8@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent receptor MAG.T22.56_01630 485918.Cpin_0169 2e-08 65.1 Bacteria tmoA GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1,3.2.2.10 ko:K00688,ko:K06966,ko:K07089,ko:K07402,ko:K15760,ko:K16157,ko:K16242,ko:K18223,ko:K22353,ko:K22357 ko00230,ko00240,ko00361,ko00362,ko00500,ko00623,ko00625,ko00640,ko00680,ko01100,ko01110,ko01120,ko01200,ko01220,ko02026,ko04217,ko04910,ko04922,ko04931,map00230,map00240,map00361,map00362,map00500,map00623,map00625,map00640,map00680,map01100,map01110,map01120,map01200,map01220,map02026,map04217,map04910,map04922,map04931 M00174,M00538,M00548 R00182,R00510,R01142,R02111,R02550,R03560,R03562,R03608,R05444,R05666,R10042,R10043,R10702,R11901 RC00046,RC00063,RC00173,RC00269,RC00318,RC00490,RC01383,RC03249 ko00000,ko00001,ko00002,ko01000 GT35 Bacteria COG3350@1,COG3350@2 NA|NA|NA T monooxygenase activity MAG.T22.56_01631 1267211.KI669560_gene2468 3.1e-63 248.1 Sphingobacteriia ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1IS80@117747,4NERA@976,COG1607@1,COG1607@2 NA|NA|NA I PFAM thioesterase superfamily MAG.T22.56_01632 1123248.KB893348_gene232 1.3e-115 423.3 Sphingobacteriia ko:K07263 ko00000,ko01000,ko01002 Bacteria 1IQAH@117747,4NEPT@976,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 MAG.T22.56_01633 313603.FB2170_06940 1.1e-132 479.9 Flavobacteriia ko:K07240 ko00000,ko02000 2.A.51.1 Bacteria 1HXXV@117743,4NNZ1@976,COG2059@1,COG2059@2 NA|NA|NA P chromate transporter, chromate ion transporter (CHR) family MAG.T22.56_01634 485918.Cpin_4998 1.4e-165 589.3 Sphingobacteriia cat2 3.1.2.1 ko:K01067 ko00620,map00620 R00227 RC00004,RC00012 ko00000,ko00001,ko01000 Bacteria 1IPAZ@117747,4NFS3@976,COG0427@1,COG0427@2 NA|NA|NA C acetyl-CoA hydrolase MAG.T22.56_01635 485918.Cpin_6049 9.1e-63 246.5 Sphingobacteriia msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 1J0CH@117747,4NP9M@976,COG0229@1,COG0229@2 NA|NA|NA O SelR domain MAG.T22.56_01636 485918.Cpin_1159 9e-84 316.6 Sphingobacteriia nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1IPXY@117747,4NFF3@976,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T22.56_01637 926549.KI421517_gene3432 5.3e-35 154.5 Cytophagia Bacteria 47Q2D@768503,4NM6B@976,COG2143@1,COG2143@2 NA|NA|NA O Protein of unknown function, DUF255 MAG.T22.56_01638 929556.Solca_3984 8.7e-207 726.5 Sphingobacteriia gltX 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 1IPV4@117747,4NEED@976,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) MAG.T22.56_01639 1313421.JHBV01000032_gene1682 1.1e-20 107.8 Bacteroidetes ko:K12057 ko00000,ko02044 3.A.7.11.1 Bacteria 4NNXC@976,COG0526@1,COG0526@2,COG1404@1,COG1404@2,COG3291@1,COG3291@2 NA|NA|NA CO Outer membrane protein Omp28 MAG.T22.56_01640 700598.Niako_5647 9.7e-224 782.7 Sphingobacteriia glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 1IPE0@117747,4NE1C@976,COG0423@1,COG0423@2 NA|NA|NA J Catalyzes the attachment of glycine to tRNA(Gly) MAG.T22.56_01642 1227739.Hsw_1186 1.1e-45 190.3 Cytophagia Bacteria 2DBUB@1,2ZB53@2,47P3Z@768503,4NMWS@976 NA|NA|NA MAG.T22.56_01643 504472.Slin_3489 1.6e-95 356.3 Cytophagia yhjA 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 47K55@768503,4NE4P@976,COG1858@1,COG1858@2 NA|NA|NA C cytochrome c peroxidase MAG.T22.56_01645 485918.Cpin_0673 2.1e-94 352.1 Sphingobacteriia Bacteria 1INQ4@117747,4NGXP@976,COG0745@1,COG0745@2 NA|NA|NA T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain MAG.T22.56_01647 485918.Cpin_1295 5.2e-118 431.4 Sphingobacteriia tig ko:K03545 ko00000 Bacteria 1ISDW@117747,4NE99@976,COG0544@1,COG0544@2 NA|NA|NA O COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) MAG.T22.56_01648 1122139.KB907875_gene2575 1.4e-24 118.6 Oceanospirillales Bacteria 1N72W@1224,1S8YP@1236,1XMJZ@135619,COG2261@1,COG2261@2 NA|NA|NA S membrane MAG.T22.56_01651 485918.Cpin_1419 1.1e-33 149.8 Sphingobacteriia pccA 6.4.1.3 ko:K01965,ko:K02160 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859 RC00040,RC00097,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 1ITD7@117747,4NQ86@976,COG4770@1,COG4770@2 NA|NA|NA I Biotin lipoyl attachment domain-containing protein MAG.T22.56_01652 485918.Cpin_1418 4.3e-153 548.9 Sphingobacteriia pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1INM2@117747,4NFTN@976,COG0308@1,COG0308@2,COG1413@1,COG1413@2 NA|NA|NA CE PFAM Peptidase M1 membrane alanine aminopeptidase MAG.T22.56_01653 1123248.KB893314_gene3659 3.5e-50 204.9 Sphingobacteriia coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 ko:K00859,ko:K07566 ko00770,ko01100,map00770,map01100 M00120 R00130,R10463 RC00002,RC00078,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 Bacteria 1IS7R@117747,4NQKS@976,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A MAG.T22.56_01654 1267211.KI669560_gene1835 1.5e-21 109.0 Sphingobacteriia yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1ITXA@117747,4NUT4@976,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit YajC MAG.T22.56_01655 1122226.AUHX01000004_gene1754 4.6e-27 127.9 Flavobacteriia Bacteria 1IJMJ@117743,2CG1Y@1,31EK1@2,4NUTU@976 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T22.56_01656 485918.Cpin_6247 8e-78 297.4 Sphingobacteriia nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1ISHE@117747,4NDVR@976,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons MAG.T22.56_01657 1346330.M472_07945 2.4e-45 188.7 Sphingobacteriia Bacteria 1ITCQ@117747,4NPQC@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_01658 1107311.Q767_15550 2.4e-79 302.8 Flavobacterium Bacteria 1HZBQ@117743,2NWPI@237,4NFYX@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_01659 518766.Rmar_2008 2.1e-151 542.3 Bacteroidetes Order II. Incertae sedis gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1FJ1P@1100069,4NEB7@976,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T22.56_01660 1454007.JAUG01000004_gene2661 5.9e-58 230.7 Sphingobacteriia Bacteria 1ISBC@117747,4NNIC@976,COG2755@1,COG2755@2 NA|NA|NA E COG2755 Lysophospholipase L1 and related MAG.T22.56_01662 1124780.ANNU01000040_gene393 1.2e-27 129.4 Cytophagia Bacteria 47VXQ@768503,4P643@976,COG5496@1,COG5496@2 NA|NA|NA S Thioesterase MAG.T22.56_01664 1121887.AUDK01000002_gene2113 2.1e-11 75.1 Flavobacterium Bacteria 1IN4F@117743,2P0SY@237,4PPKN@976,COG2608@1,COG2608@2 NA|NA|NA P mercury ion transmembrane transporter activity MAG.T22.56_01665 1267211.KI669560_gene90 4.8e-168 598.2 Sphingobacteriia ko:K16089 ko00000,ko02000 1.B.14.1,1.B.14.10 Bacteria 1IP85@117747,4NE7A@976,COG1629@1,COG2608@1,COG2608@2,COG4771@2 NA|NA|NA P TonB-dependent receptor MAG.T22.56_01666 1408813.AYMG01000023_gene2046 3.7e-150 538.1 Sphingobacteriia Bacteria 1IPF3@117747,2CD20@1,2Z7SQ@2,4NEQ1@976 NA|NA|NA MAG.T22.56_01667 485917.Phep_0703 7.1e-97 360.9 Sphingobacteriia ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IQSZ@117747,4NKB0@976,COG0842@1,COG0842@2 NA|NA|NA V transport, permease protein MAG.T22.56_01668 468059.AUHA01000002_gene291 4.7e-100 371.3 Sphingobacteriia iaaA 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 1IQI3@117747,4NF1U@976,COG1446@1,COG1446@2 NA|NA|NA E Asparaginase MAG.T22.56_01669 700598.Niako_2958 1.6e-18 99.0 Sphingobacteriia Bacteria 1IXGM@117747,4NJYT@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain containing protein MAG.T22.56_01670 1336803.PHEL49_1624 2.9e-139 501.9 Polaribacter hutI 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 1HYME@117743,3VV52@52959,4NE6C@976,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T22.56_01671 485918.Cpin_1658 1.2e-79 302.8 Sphingobacteriia efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1IP45@117747,4NDXA@976,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase MAG.T22.56_01672 485918.Cpin_1659 1.5e-46 192.6 Sphingobacteriia accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1ISET@117747,4NM8U@976,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA MAG.T22.56_01673 925409.KI911562_gene1538 1.5e-231 808.5 Sphingobacteriia accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1INM0@117747,4NFEQ@976,COG0439@1,COG0439@2 NA|NA|NA I acetyl-CoA carboxylase, biotin carboxylase MAG.T22.56_01674 1453498.LG45_07370 3.1e-163 581.3 Flavobacterium rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1HX7N@117743,2NTNX@237,4NE9V@976,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily MAG.T22.56_01675 1233951.IO90_01765 1.6e-133 482.3 Chryseobacterium rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 1HWWH@117743,3HHTJ@358033,4NE1U@976,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis MAG.T22.56_01676 1267211.KI669560_gene2004 6.4e-65 253.8 Sphingobacteriia yheB Bacteria 1IZQF@117747,4NIDM@976,COG4399@1,COG4399@2 NA|NA|NA S Belongs to the UPF0754 family MAG.T22.56_01677 485918.Cpin_5427 1.8e-188 665.2 Sphingobacteriia hmgA 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPEN@117747,4NEYZ@976,COG3508@1,COG3508@2 NA|NA|NA Q homogentisate 12-dioxygenase MAG.T22.56_01678 485918.Cpin_7294 3.3e-106 391.7 Sphingobacteriia 2.3.1.157,2.7.7.23,2.7.7.24 ko:K00973,ko:K02414,ko:K04042,ko:K21449 ko00520,ko00521,ko00523,ko00525,ko01100,ko01130,ko02040,map00520,map00521,map00523,map00525,map01100,map01130,map02040 M00362,M00793 R00416,R02328,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko02000,ko02035 1.B.40.2 Bacteria 1J0PR@117747,4PMCK@976,COG1044@1,COG1044@2,COG1209@1,COG1209@2 NA|NA|NA M Nucleotidyl transferase MAG.T22.56_01679 1313421.JHBV01000003_gene656 3.8e-45 187.6 Sphingobacteriia 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1IT31@117747,4NNNG@976,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.56_01680 700598.Niako_1562 1.9e-267 928.3 Sphingobacteriia ubiD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_4669,iIT341.HP0396 Bacteria 1IR14@117747,4NHHV@976,COG0043@1,COG0043@2 NA|NA|NA H Belongs to the UbiD family MAG.T22.56_01681 1122605.KB893647_gene486 2.3e-25 122.5 Bacteroidetes Bacteria 2DQH4@1,336TE@2,4NXA3@976 NA|NA|NA S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family MAG.T22.56_01682 1227266.HMPREF1551_01896 1e-14 86.7 Capnocytophaga Bacteria 1ES7Q@1016,1I6FZ@117743,2ETCB@1,33KW7@2,4NY4M@976 NA|NA|NA S Domain of unknown function (DUF4878) MAG.T22.56_01683 391596.PBAL39_18399 1.3e-170 606.3 Sphingobacteriia spmB ko:K06373,ko:K06374 ko00000 Bacteria 1IP2N@117747,4NFUN@976,COG0700@1,COG0700@2,COG2715@1,COG2715@2 NA|NA|NA S membrane protein required for spore maturation in B.subtilis MAG.T22.56_01684 391596.PBAL39_14589 1.2e-60 239.6 Sphingobacteriia yvdD 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1IS44@117747,4NGWU@976,COG1611@1,COG1611@2 NA|NA|NA S Cytokinin riboside 5'-monophosphate phosphoribohydrolase MAG.T22.56_01685 700598.Niako_5271 7e-191 673.3 Sphingobacteriia lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1INXN@117747,4NE7X@976,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T22.56_01686 485918.Cpin_3664 1.2e-123 449.5 Sphingobacteriia accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 1IPMT@117747,4NFMH@976,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA MAG.T22.56_01687 485918.Cpin_5487 2.3e-133 481.9 Sphingobacteriia pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1IP8Y@117747,4NFIU@976,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family MAG.T22.56_01688 700598.Niako_1166 2.8e-59 235.0 Sphingobacteriia pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1IQWE@117747,4NFI1@976,COG2065@1,COG2065@2 NA|NA|NA F uracil phosphoribosyltransferase MAG.T22.56_01689 485918.Cpin_5072 1.1e-105 390.2 Sphingobacteriia yhaZ Bacteria 1IR7N@117747,4NH5H@976,COG4335@1,COG4335@2 NA|NA|NA L DNA alkylation repair MAG.T22.56_01690 1121481.AUAS01000002_gene3229 3.7e-62 244.6 Cytophagia Bacteria 47PQT@768503,4NIP0@976,COG0664@1,COG0664@2 NA|NA|NA T cyclic nucleotide-binding MAG.T22.56_01691 1296416.JACB01000001_gene3581 4.1e-27 127.5 Aquimarina Bacteria 1I2Z7@117743,2CWCM@1,2YJMU@290174,32SZF@2,4NSAZ@976 NA|NA|NA S Domain of unknown function (DUF4260) MAG.T22.56_01692 1267211.KI669560_gene2044 6e-101 374.0 Sphingobacteriia cvfB ko:K00243 ko00000 Bacteria 1IS7G@117747,4NGS6@976,COG2996@1,COG2996@2 NA|NA|NA S S1 domain MAG.T22.56_01693 1408473.JHXO01000007_gene936 7.1e-11 74.7 Bacteroidia Bacteria 2DQZ0@1,2FXN5@200643,339GF@2,4NWV9@976 NA|NA|NA MAG.T22.56_01695 1121896.JMLU01000031_gene2260 1.2e-35 156.4 Flavobacterium Bacteria 1IBTE@117743,2E12W@1,2NSE3@237,32WIH@2,4NTHQ@976 NA|NA|NA MAG.T22.56_01696 485918.Cpin_0160 3.5e-22 112.1 Sphingobacteriia Bacteria 1IZ4B@117747,28JHY@1,2Z9BE@2,4NGKG@976 NA|NA|NA MAG.T22.56_01697 485918.Cpin_0233 2e-269 935.3 Sphingobacteriia alr 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1IP9R@117747,4NEXM@976,COG0770@1,COG0770@2,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids MAG.T22.56_01698 760192.Halhy_6385 5.7e-35 155.2 Bacteroidetes Bacteria 2E7J5@1,3321E@2,4NWSR@976 NA|NA|NA MAG.T22.56_01699 485918.Cpin_0232 1.5e-127 463.4 Sphingobacteriia gldG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IR8V@117747,4NF62@976,COG3225@1,COG3225@2 NA|NA|NA N transport system involved in gliding motility, auxiliary component MAG.T22.56_01700 485918.Cpin_0231 1.6e-69 269.6 Sphingobacteriia ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IRI4@117747,4NG5G@976,COG1277@1,COG1277@2 NA|NA|NA S TIGRFAM Gliding motility-associated ABC transporter permease protein GldF MAG.T22.56_01701 485918.Cpin_0445 6.6e-98 364.4 Sphingobacteriia ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1IRSG@117747,4NGHH@976,COG0739@1,COG0739@2 NA|NA|NA M PFAM Peptidase family M23 MAG.T22.56_01703 485918.Cpin_0907 3.8e-58 231.9 Sphingobacteriia bla 3.5.2.6 ko:K17838,ko:K18793,ko:K18794,ko:K18973,ko:K18976,ko:K19210,ko:K19211,ko:K19212,ko:K19318,ko:K19321,ko:K21277,ko:K22333,ko:K22334,ko:K22351 ko01501,map01501 R06363 RC01499 br01600,ko00000,ko00001,ko01000,ko01504 Bacteria 1IYF8@117747,4NH11@976,COG2602@1,COG2602@2 NA|NA|NA V Penicillin binding protein transpeptidase domain MAG.T22.56_01704 643867.Ftrac_2976 1.9e-55 222.2 Cytophagia menG 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 47JXK@768503,4NEDR@976,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) MAG.T22.56_01705 215803.DB30_7176 4.1e-81 307.8 Myxococcales amnC 1.2.1.32,1.2.1.60,1.2.1.85 ko:K00151,ko:K10217 ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00569 R02762,R03889,R04418,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,2X1X6@28221,2YWKW@29,42N0C@68525,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T22.56_01706 755732.Fluta_1229 8.7e-61 239.6 Cryomorphaceae amnD 3.5.99.5,4.1.1.77 ko:K01617,ko:K15067 ko00362,ko00380,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R03887,R05374 RC00751,RC01015,RC02672 ko00000,ko00001,ko00002,ko01000 Bacteria 1I1II@117743,2PARM@246874,4NMHF@976,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP MAG.T22.56_01708 1267211.KI669560_gene2871 6.6e-176 623.6 Sphingobacteriia bfmBA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00167,ko:K11381,ko:K21416,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IP3Q@117747,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type MAG.T22.56_01709 1267211.KI669560_gene2871 1.3e-96 359.4 Sphingobacteriia bfmBA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00167,ko:K11381,ko:K21416,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IP3Q@117747,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type MAG.T22.56_01710 485918.Cpin_0839 1.8e-243 849.4 Sphingobacteriia nagA 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1IP6G@117747,4NET8@976,COG1472@1,COG1472@2,COG1680@1,COG1680@2 NA|NA|NA G PFAM glycoside hydrolase family 3 MAG.T22.56_01711 925409.KI911562_gene1092 5e-183 647.9 Sphingobacteriia mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1IPN2@117747,4NDWJ@976,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex MAG.T22.56_01712 700598.Niako_1111 1.1e-72 281.6 Sphingobacteriia Bacteria 1IT0V@117747,4NS69@976,COG3291@1,COG3291@2 NA|NA|NA M C-terminal domain of CHU protein family MAG.T22.56_01713 1218103.CIN01S_12_00170 3.5e-50 204.9 Chryseobacterium ydaF_1 Bacteria 1I1MN@117743,3ZSTN@59732,4NM3W@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_01714 1313421.JHBV01000049_gene57 9.1e-36 159.1 Bacteria Bacteria COG2133@1,COG2133@2,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA G pyrroloquinoline quinone binding MAG.T22.56_01715 925409.KI911562_gene2257 5.7e-101 375.6 Sphingobacteriia Bacteria 1IPPH@117747,4NE4W@976,COG0457@1,COG0457@2,COG1729@1,COG1729@2 NA|NA|NA S PFAM Tetratricopeptide MAG.T22.56_01716 1123248.KB893316_gene4577 3.1e-59 236.5 Sphingobacteriia Bacteria 1IPFQ@117747,4PKB3@976,COG1629@1,COG4771@2 NA|NA|NA P receptor MAG.T22.56_01718 700598.Niako_6870 7e-157 560.5 Sphingobacteriia purD 6.3.4.13,6.3.5.3 ko:K01945,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04463 RC00010,RC00090,RC00166,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPBB@117747,4NEUN@976,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family MAG.T22.56_01719 1341155.FSS13T_09480 3.8e-208 731.1 Flavobacterium ko:K03305 ko00000 2.A.17 Bacteria 1HY6B@117743,2NUAF@237,4NGWH@976,COG3104@1,COG3104@2 NA|NA|NA U Amino acid transporter MAG.T22.56_01721 1123248.KB893333_gene2782 8.5e-242 843.2 Sphingobacteriia ko:K07386 ko00000,ko01000,ko01002 Bacteria 1IQ1D@117747,4NEYB@976,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 MAG.T22.56_01722 1185876.BN8_02012 6.9e-58 230.7 Bacteria Bacteria 2F4UR@1,33XH2@2 NA|NA|NA MAG.T22.56_01723 1123248.KB893315_gene3165 2.4e-255 887.9 Sphingobacteriia prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1IP50@117747,4NFEZ@976,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP MAG.T22.56_01725 929703.KE386491_gene3786 1.1e-43 184.9 Cytophagia Bacteria 47Q7U@768503,4NJEF@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.56_01726 929556.Solca_2027 3.2e-58 231.5 Sphingobacteriia Bacteria 1ISGA@117747,4PM4N@976,COG1247@1,COG1247@2 NA|NA|NA M Gnat family MAG.T22.56_01728 700598.Niako_6592 2.9e-58 232.3 Sphingobacteriia ko:K12976,ko:K21572 ko00000,ko01000,ko01005,ko02000 8.A.46.1,8.A.46.3 Bacteria 1ISTC@117747,4NNPF@976,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.56_01729 485918.Cpin_1049 2.7e-99 368.6 Sphingobacteriia nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1IPBF@117747,4NFG5@976,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP MAG.T22.56_01730 1279009.ADICEAN_01784 9.2e-70 271.2 Cytophagia Bacteria 47KUK@768503,4NF9Y@976,COG4775@1,COG4775@2 NA|NA|NA M PFAM surface antigen variable number repeat MAG.T22.56_01731 945713.IALB_1082 5e-29 136.0 Bacteria 3.1.3.1,3.1.3.5,3.1.3.8,3.6.1.45 ko:K01077,ko:K01083,ko:K07004,ko:K11751 ko00230,ko00240,ko00562,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00562,map00730,map00760,map00790,map01100,map01110,map02020 M00126 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R03371,R04620 RC00017,RC00078 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.56_01732 468059.AUHA01000003_gene1950 4.5e-07 60.8 Sphingobacteriia folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1ITVJ@117747,4NQ53@976,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin MAG.T22.56_01733 509635.N824_16945 1.3e-65 255.8 Sphingobacteriia Bacteria 1IS82@117747,4NQI7@976,COG2128@1,COG2128@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T22.56_01734 929556.Solca_0770 2e-31 141.7 Sphingobacteriia Bacteria 1ITPC@117747,4NS2I@976,COG3795@1,COG3795@2 NA|NA|NA S PFAM YCII-related domain MAG.T22.56_01735 485917.Phep_1213 1.3e-152 546.2 Sphingobacteriia ko:K03088 ko00000,ko03021 Bacteria 1IPXA@117747,4NGCS@976,COG4941@1,COG4941@2 NA|NA|NA K RNA polymerase sigma factor MAG.T22.56_01737 485918.Cpin_0431 5.5e-42 178.3 Sphingobacteriia ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018 R05712 RC00176 ko00000,ko02000 9.B.14.1 Bacteria 1ISTW@117747,4NGHU@976,COG3088@1,COG3088@2 NA|NA|NA O Psort location CytoplasmicMembrane, score MAG.T22.56_01738 485918.Cpin_0430 4.1e-120 438.0 Sphingobacteriia batA ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1IP6P@117747,4NDUC@976,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A MAG.T22.56_01739 485918.Cpin_0542 0.0 1083.2 Sphingobacteriia uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1INSY@117747,4NE6E@976,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage MAG.T22.56_01741 1121875.KB907549_gene1887 1.4e-11 77.4 Flavobacteriia Bacteria 1I22B@117743,28PUA@1,2ZCJB@2,4NMQI@976 NA|NA|NA MAG.T22.56_01742 485918.Cpin_0500 3.4e-110 404.8 Sphingobacteriia Bacteria 1IQ9R@117747,4NF4H@976,COG1853@1,COG1853@2 NA|NA|NA S flavin reductase MAG.T22.56_01743 649349.Lbys_2494 1.6e-35 156.0 Cytophagia Bacteria 47YES@768503,4PN8J@976,COG0457@1,COG0457@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.56_01744 1166018.FAES_1455 3.8e-17 96.3 Cytophagia Bacteria 47WA8@768503,4P8TK@976,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain MAG.T22.56_01745 1250006.JHZZ01000001_gene2170 2.4e-29 135.6 Polaribacter 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1I4PX@117743,3VWQP@52959,4NSIH@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.56_01746 1223410.KN050846_gene2532 6.9e-28 131.7 Flavobacteriia Bacteria 1I8V8@117743,4P2SE@976,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity MAG.T22.56_01747 929704.Myrod_1120 1.3e-99 369.8 Myroides fieF Bacteria 1HY4C@117743,47HW2@76831,4NEID@976,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family MAG.T22.56_01748 1121481.AUAS01000003_gene3943 5.6e-08 63.9 Cytophagia Bacteria 2E8WY@1,33373@2,47RXW@768503,4NV40@976 NA|NA|NA MAG.T22.56_01749 485918.Cpin_2999 2.3e-193 682.6 Sphingobacteriia quiP 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 1IPU7@117747,4NEIX@976,COG2366@1,COG2366@2 NA|NA|NA S COG2366 Protein related to penicillin acylase MAG.T22.56_01750 945713.IALB_3172 1.7e-72 279.6 Bacteria mltD_2 Bacteria COG0741@1,COG0741@2 NA|NA|NA M lytic transglycosylase activity MAG.T22.56_01751 1121373.KB903621_gene1739 1.2e-57 229.6 Bacteroidetes Bacteria 2DMTA@1,32TIJ@2,4NT58@976 NA|NA|NA MAG.T22.56_01755 1144313.PMI10_01170 7.9e-49 199.9 Flavobacterium Bacteria 1I8RV@117743,298UU@1,2NWGH@237,2ZVYZ@2,4NPH1@976 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.56_01756 485918.Cpin_6196 1.1e-15 90.1 Bacteria Bacteria 2DM4T@1,31QCU@2 NA|NA|NA MAG.T22.56_01757 762903.Pedsa_0006 4.6e-63 247.7 Sphingobacteriia lemA ko:K03744 ko00000 Bacteria 1IS2G@117747,4NMD3@976,COG1704@1,COG1704@2 NA|NA|NA S LemA family MAG.T22.56_01758 1267211.KI669560_gene1266 7e-35 153.7 Sphingobacteriia Z012_08985 ko:K08988 ko00000 Bacteria 1IT0H@117747,4NQIT@976,COG3762@1,COG3762@2 NA|NA|NA S TPM domain MAG.T22.56_01759 1239962.C943_00919 7.8e-42 177.6 Cytophagia Z012_08980 3.4.24.3 ko:K01387,ko:K06872 ko00000,ko01000,ko01002,ko02042 Bacteria 47NDD@768503,4NF4P@976,COG1512@1,COG1512@2 NA|NA|NA S Beta-propeller domains of methanol dehydrogenase type MAG.T22.56_01760 1123248.KB893319_gene3967 5.2e-82 311.2 Sphingobacteriia ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Bacteria 1IRUR@117747,4NF5A@976,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group MAG.T22.56_01761 925409.KI911562_gene1024 4.6e-52 211.1 Sphingobacteriia ctaE 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 1IST1@117747,4NFA7@976,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase subunit III MAG.T22.56_01762 485918.Cpin_0519 7e-85 320.5 Sphingobacteriia coxP 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 1INPX@117747,4NDYG@976,COG1845@1,COG1845@2 NA|NA|NA C oxidase subunit III MAG.T22.56_01763 485918.Cpin_0518 2.8e-14 85.1 Sphingobacteriia coxQ Bacteria 1IU6V@117747,4PGS2@976,COG5605@1,COG5605@2 NA|NA|NA S Prokaryotic Cytochrome C oxidase subunit IV MAG.T22.56_01764 485918.Cpin_0517 2.5e-52 212.2 Bacteroidetes ypmQ ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 4NFH2@976,COG1999@1,COG1999@2 NA|NA|NA S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems MAG.T22.56_01765 929713.NIASO_13350 1.4e-58 232.6 Sphingobacteriia yozB ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 1ITGM@117747,4NM5N@976,COG2322@1,COG2322@2 NA|NA|NA S Protein of unknown function (DUF420) MAG.T22.56_01766 1123248.KB893348_gene123 3.7e-10 70.5 Sphingobacteriia Bacteria 1IUFE@117747,2ACEV@1,3120D@2,4PGV7@976 NA|NA|NA MAG.T22.56_01767 226186.BT_1007 1.5e-10 73.6 Bacteroidaceae Bacteria 2FPF9@200643,4AMYW@815,4NSAQ@976,COG3595@1,COG3595@2 NA|NA|NA S Putative auto-transporter adhesin, head GIN domain MAG.T22.56_01768 1124780.ANNU01000012_gene3934 3.6e-36 157.9 Cytophagia Bacteria 47R93@768503,4NQCK@976,COG4731@1,COG4731@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2147) MAG.T22.56_01769 693979.Bache_0659 5.8e-50 203.8 Bacteroidaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 2FNMW@200643,4AP5M@815,4NNFF@976,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality MAG.T22.56_01770 700598.Niako_7085 4.9e-161 574.3 Sphingobacteriia mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1IPFD@117747,4NECT@976,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 MAG.T22.56_01771 1121870.AUAA01000056_gene1158 4e-30 137.5 Chryseobacterium Bacteria 1IM6Y@117743,3HJ44@358033,4PK3D@976,COG2452@1,COG2452@2 NA|NA|NA L Helix-turn-helix domain MAG.T22.56_01772 1123248.KB893334_gene2741 2.3e-124 452.2 Sphingobacteriia Bacteria 1IPVQ@117747,4PKC8@976,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase SAM-like domain MAG.T22.56_01773 1189612.A33Q_2767 1.2e-133 482.6 Cytophagia dinD ko:K07741,ko:K14623 ko00000,ko03400 Bacteria 47TBU@768503,4NJ37@976,COG3645@1,COG3645@2 NA|NA|NA S DNA-damage-inducible protein D MAG.T22.56_01774 449447.MAE_08180 8.5e-310 1069.7 Cyanobacteria Bacteria 1G36A@1117,COG0286@1,COG0286@2 NA|NA|NA V helicase MAG.T22.56_01775 1408813.AYMG01000020_gene2987 3.9e-82 312.4 Sphingobacteriia Bacteria 1IYDU@117747,2EU5P@1,33MNA@2,4NYQG@976 NA|NA|NA MAG.T22.56_01776 1454007.JAUG01000005_gene2824 3e-85 323.9 Sphingobacteriia 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1IYB8@117747,4P4P6@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA M COG3209 Rhs family protein MAG.T22.56_01777 357276.EL88_18555 2e-165 588.6 Bacteroidaceae fbaB GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640 Bacteria 2FKZ7@200643,4APQV@815,4NEUM@976,COG1830@1,COG1830@2 NA|NA|NA G COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes MAG.T22.56_01778 386456.JQKN01000010_gene700 1.1e-31 144.8 Archaea 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 GT66 Archaea arCOG00567@1,arCOG00567@2157 NA|NA|NA S glycosyl transferase family MAG.T22.56_01779 1227739.Hsw_0498 7.5e-18 98.2 Bacteria Bacteria COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase activity MAG.T22.56_01781 743722.Sph21_4485 1.2e-87 329.7 Sphingobacteriia desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 1IRSQ@117747,4NE0I@976,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase MAG.T22.56_01782 244581.IM40_01185 1.9e-10 72.0 Alphaproteobacteria yffH Bacteria 1N317@1224,2UDZ1@28211,COG0494@1,COG0494@2 NA|NA|NA L nUDIX hydrolase MAG.T22.56_01783 929562.Emtol_3458 3.9e-36 157.5 Cytophagia 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 47R6X@768503,4NQRK@976,COG0346@1,COG0346@2 NA|NA|NA E bleomycin resistance protein MAG.T22.56_01784 485918.Cpin_3666 1.1e-74 286.6 Sphingobacteriia fecB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1IRZV@117747,4NI2Y@976,COG0614@1,COG0614@2 NA|NA|NA P PFAM periplasmic binding protein MAG.T22.56_01786 485918.Cpin_3667 4.1e-161 574.3 Sphingobacteriia cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQU6@117747,4NDZ9@976,COG0031@1,COG0031@2,COG3620@1,COG3620@2 NA|NA|NA E Cystathionine beta-synthase MAG.T22.56_01787 1453500.AT05_01190 2.9e-15 89.0 Flavobacteriia Bacteria 1HYX0@117743,4NESV@976,COG3391@1,COG3391@2 NA|NA|NA G Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_01788 153721.MYP_4104 4.7e-80 305.8 Cytophagia btuB ko:K02014,ko:K16092 ko00000,ko02000 1.B.14,1.B.14.3 Bacteria 47M0G@768503,4NED9@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug MAG.T22.56_01789 153721.MYP_4447 6e-24 119.0 Cytophagia arnT Bacteria 47R5I@768503,4NQJA@976,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T22.56_01791 760192.Halhy_5636 2.2e-38 165.6 Sphingobacteriia ko:K03088 ko00000,ko03021 Bacteria 1IS8X@117747,4NP5U@976,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase sigma factor, sigma-70 family MAG.T22.56_01793 485918.Cpin_4697 2.4e-99 368.6 Sphingobacteriia CP_0807 ko:K09125 ko00000 Bacteria 1IQJP@117747,4NFP3@976,COG1738@1,COG1738@2 NA|NA|NA S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage MAG.T22.56_01794 391587.KAOT1_11186 1.8e-28 133.3 Flavobacteriia Bacteria 1HZ7Z@117743,4NI8N@976,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit MAG.T22.56_01795 1121285.AUFK01000017_gene3166 2e-24 119.0 Chryseobacterium Bacteria 1IF2G@117743,2AARW@1,3104A@2,3ZT1B@59732,4PEH7@976 NA|NA|NA MAG.T22.56_01796 755732.Fluta_3714 0.0 1629.0 Bacteroidetes ko:K03296 ko00000 2.A.6.2 Bacteria 4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.56_01797 1267211.KI669560_gene841 3.8e-116 424.9 Sphingobacteriia Bacteria 1IQVF@117747,4NF23@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.56_01798 755732.Fluta_3716 2.6e-138 498.8 Flavobacteriia ko:K03287 ko00000 1.B.17 Bacteria 1HYW1@117743,4NF4X@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.56_01799 755732.Fluta_3717 5.4e-25 120.2 Cryomorphaceae Bacteria 1ID52@117743,2PC1N@246874,4P6B6@976,COG1917@1,COG1917@2 NA|NA|NA S Cupin 2, conserved barrel domain protein MAG.T22.56_01800 755732.Fluta_3718 3.2e-35 154.8 Cryomorphaceae Bacteria 1IFB5@117743,2BFVS@1,2PC3U@246874,32WJ0@2,4PGMC@976 NA|NA|NA MAG.T22.56_01801 1267211.KI669560_gene837 3.6e-32 144.4 Bacteroidetes Bacteria 2AQ4B@1,32TV2@2,4NT63@976 NA|NA|NA MAG.T22.56_01802 700598.Niako_5598 1.1e-11 75.5 Sphingobacteriia tatA ko:K03116 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1IUFV@117747,4NUNH@976,COG1826@1,COG1826@2 NA|NA|NA U Sec-independent protein translocase protein TatA MAG.T22.56_01803 485918.Cpin_1334 2.6e-51 209.5 Sphingobacteriia ko:K08307 ko00000,ko01000,ko01011 Bacteria 1IRNH@117747,4NEKW@976,COG0741@1,COG0741@2 NA|NA|NA M PFAM Transglycosylase SLT domain MAG.T22.56_01804 925409.KI911562_gene2988 1.5e-23 115.2 Sphingobacteriia rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ITAU@117747,4NSB1@976,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA MAG.T22.56_01805 926562.Oweho_0827 1.3e-19 104.0 Cryomorphaceae tlpB 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 Bacteria 1IGAY@117743,2PC14@246874,4PIJN@976,COG0526@1,COG0526@2 NA|NA|NA CO COG0526, thiol-disulfide isomerase and thioredoxins MAG.T22.56_01807 445961.IW15_14765 9.2e-89 334.0 Chryseobacterium Bacteria 1HZBQ@117743,3ZR3X@59732,4NFYX@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_01808 1313421.JHBV01000030_gene2227 4.1e-100 372.5 Bacteroidetes ko:K05286 ko00563,ko01100,map00563,map01100 M00065 R05922 ko00000,ko00001,ko00002,ko01000,ko01003 GT22 Bacteria 4NKCK@976,COG0457@1,COG0457@2,COG1807@1,COG1807@2 NA|NA|NA M Tetratricopeptide repeat MAG.T22.56_01809 1122621.ATZA01000003_gene1340 2.3e-59 235.7 Bacteroidetes Bacteria 4NEZS@976,COG2227@1,COG2227@2 NA|NA|NA H Methionine biosynthesis protein MetW MAG.T22.56_01810 485918.Cpin_1328 2.9e-45 188.3 Sphingobacteriia rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1IRXR@117747,4NNY8@976,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family MAG.T22.56_01811 485918.Cpin_1327 1.1e-109 402.9 Sphingobacteriia ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1INMC@117747,4NDZ2@976,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY MAG.T22.56_01812 1123008.KB905696_gene3087 9.9e-157 559.7 Porphyromonadaceae yceA ko:K07146 ko00000 Bacteria 22WJZ@171551,2FRHQ@200643,4NEG6@976,COG1054@1,COG1054@2 NA|NA|NA S Rhodanase C-terminal MAG.T22.56_01814 555500.I215_06892 3.1e-07 63.2 Flavobacteriia Bacteria 1I6JV@117743,2E5D4@1,33GE1@2,4NY94@976 NA|NA|NA MAG.T22.56_01816 743722.Sph21_3658 1.4e-49 203.0 Sphingobacteriia ko:K03424 ko00000,ko01000 Bacteria 1ITD3@117747,4NSGW@976,COG0084@1,COG0084@2 NA|NA|NA L PFAM TatD related DNase MAG.T22.56_01817 743722.Sph21_3659 1.6e-94 352.4 Sphingobacteriia ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029,ko:K22132 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000,ko03016 Bacteria 1IRVV@117747,4NEKB@976,COG1179@1,COG1179@2 NA|NA|NA H UBA THIF-type NAD FAD binding MAG.T22.56_01818 700598.Niako_4481 0.0 1249.2 Sphingobacteriia acnA 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1INUB@117747,4NDZT@976,COG1048@1,COG1048@2 NA|NA|NA C aconitate hydratase MAG.T22.56_01820 485918.Cpin_6591 9.2e-194 682.9 Sphingobacteriia icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Bacteria 1IPFB@117747,4PKW6@976,COG0538@1,COG0538@2 NA|NA|NA C Isocitrate dehydrogenase MAG.T22.56_01821 485918.Cpin_1223 1.3e-103 383.3 Sphingobacteriia phoR 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1IQ3E@117747,4NETP@976,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase MAG.T22.56_01822 485918.Cpin_1224 3e-85 321.6 Sphingobacteriia Bacteria 1IPM8@117747,4NG7D@976,COG0745@1,COG0745@2 NA|NA|NA T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain MAG.T22.56_01823 485918.Cpin_6526 1.1e-58 233.8 Sphingobacteriia ko:K09892 ko00000,ko03036 Bacteria 1ISCQ@117747,4PN6S@976,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T22.56_01824 575590.HMPREF0156_01457 1.5e-63 249.6 Bacteroidetes polB 2.7.7.7 ko:K02336,ko:K07501 ko00000,ko01000,ko03400 Bacteria 4PKQ5@976,COG0417@1,COG0417@2 NA|NA|NA L 3'-5' exonuclease related to the exonuclease domain of PolB MAG.T22.56_01825 485918.Cpin_6524 2.6e-74 285.8 Sphingobacteriia holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1IQ3N@117747,4NEIB@976,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit MAG.T22.56_01826 1408473.JHXO01000010_gene3568 1.1e-28 132.9 Bacteroidia ribF 2.7.1.26,2.7.7.2 ko:K07011,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2FM7A@200643,4NEI9@976,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family MAG.T22.56_01827 700598.Niako_0903 1.9e-37 162.2 Sphingobacteriia ribF 2.7.1.26,2.7.7.2 ko:K07011,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQGU@117747,4NEI9@976,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family MAG.T22.56_01828 1191523.MROS_1276 2.4e-22 113.6 Bacteria ydbH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria COG2304@1,COG2304@2,COG2911@1,COG2911@2 NA|NA|NA S protein secretion MAG.T22.56_01829 929713.NIASO_01705 1.5e-212 746.1 Sphingobacteriia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1J0SA@117747,4NEHN@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug Domain MAG.T22.56_01830 391596.PBAL39_16806 1.2e-78 299.7 Sphingobacteriia yugP ko:K06973 ko00000 Bacteria 1IRD0@117747,4NDWG@976,COG2738@1,COG2738@2 NA|NA|NA S PFAM Peptidase, membrane zinc metallopeptidase MAG.T22.56_01831 485918.Cpin_0946 1.5e-176 625.9 Bacteroidetes blh 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 4NE2Y@976,COG0491@1,COG0491@2,COG2897@1,COG2897@2 NA|NA|NA P COGs COG0491 Zn-dependent hydrolase including glyoxylase MAG.T22.56_01832 925409.KI911562_gene1624 5.5e-170 604.0 Sphingobacteriia pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 1IPMC@117747,4NG40@976,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family MAG.T22.56_01833 1121481.AUAS01000003_gene3676 1.3e-29 138.7 Cytophagia ko:K11016 ko03070,map03070 ko00000,ko00001,ko02042,ko02044 Bacteria 47SGA@768503,4PKQC@976,COG2831@1,COG2831@2,COG3227@1,COG3227@2 NA|NA|NA E Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_01834 1267211.KI669560_gene2848 4e-28 131.7 Sphingobacteriia ko:K07220 ko00000 Bacteria 1INNB@117747,4NI25@976,COG1392@1,COG1392@2 NA|NA|NA P COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) MAG.T22.56_01835 755732.Fluta_2865 3.9e-64 251.5 Cryomorphaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,2.7.7.80,2.8.1.11,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196,ko:K21147 ko04122,ko04621,ko05418,map04122,map04621,map05418 R07459,R07461 RC00043 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1I51Q@117743,2PC0A@246874,4NUPH@976,COG0526@1,COG0526@2,COG0607@1,COG0607@2 NA|NA|NA COP COGs COG0607 Rhodanese-related sulfurtransferase MAG.T22.56_01836 1121285.AUFK01000018_gene667 8.1e-44 183.3 Chryseobacterium ymaD Bacteria 1I3KT@117743,3ZUDM@59732,4PK2I@976,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein MAG.T22.56_01837 468059.AUHA01000003_gene1508 1.4e-36 158.7 Sphingobacteriia trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1ITPA@117747,4PKQI@976,COG0526@1,COG0526@2 NA|NA|NA O Thioredoxin MAG.T22.56_01839 694427.Palpr_2541 2.2e-32 144.8 Porphyromonadaceae ko:K03972 ko00000 Bacteria 22YT4@171551,2FV0P@200643,4NSD1@976,COG0607@1,COG0607@2 NA|NA|NA P Sulfurtransferase MAG.T22.56_01840 700598.Niako_3260 7.5e-93 347.4 Sphingobacteriia Bacteria 1IVAD@117747,4NPIX@976,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.56_01841 1131812.JQMS01000001_gene2157 4.2e-114 418.7 Flavobacterium rpoD ko:K03086,ko:K03324 ko00000,ko02000,ko03021 2.A.58.2 Bacteria 1HYFK@117743,2NWFB@237,4NHMY@976,COG1283@1,COG1283@2 NA|NA|NA P Na+/Pi-cotransporter MAG.T22.56_01843 700598.Niako_1983 3.7e-108 397.9 Sphingobacteriia dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1INN5@117747,4NEWD@976,COG2171@1,COG2171@2 NA|NA|NA E Belongs to the transferase hexapeptide repeat family MAG.T22.56_01844 761193.Runsl_2929 7.1e-224 783.5 Cytophagia 1.13.12.16 ko:K00459 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000 Bacteria 47JXU@768503,4NEGW@976,COG2070@1,COG2070@2 NA|NA|NA S 2-Nitropropane dioxygenase MAG.T22.56_01845 926562.Oweho_3448 2e-28 132.9 Cryomorphaceae Bacteria 1ICTS@117743,28JFU@1,2PC4T@246874,30YB4@2,4PC31@976 NA|NA|NA MAG.T22.56_01846 926562.Oweho_3447 4.5e-90 338.2 Flavobacteriia mauG 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1HXUF@117743,4NE4P@976,COG1858@1,COG1858@2 NA|NA|NA C cytochrome C peroxidase MAG.T22.56_01847 1313421.JHBV01000033_gene2357 8.3e-40 171.0 Sphingobacteriia Bacteria 1IPT3@117747,4NIIB@976,COG4313@1,COG4313@2 NA|NA|NA C Protein involved in meta-pathway of phenol degradation MAG.T22.56_01849 1123248.KB893386_gene1909 3.3e-43 181.4 Sphingobacteriia 1.9.3.1 ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 Bacteria 1ISPY@117747,4NMD5@976,COG2010@1,COG2010@2 NA|NA|NA C PFAM cytochrome c MAG.T22.56_01850 1121896.JMLU01000024_gene2536 1.3e-303 1048.5 Flavobacterium nosZ GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 ko:K00376,ko:K02275 ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120 M00155,M00529 R00081,R02804 RC00016,RC02861 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1HYUT@117743,2NSJJ@237,4NFNE@976,COG4263@1,COG4263@2 NA|NA|NA C Nitrous oxide reductase MAG.T22.56_01851 1123248.KB893385_gene4878 4.1e-36 157.5 Sphingobacteriia rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1ISV5@117747,4NSQJ@976,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA MAG.T22.56_01852 1313421.JHBV01000026_gene436 5.1e-24 118.6 Bacteroidetes Bacteria 2DMY7@1,32UCK@2,4NSK3@976 NA|NA|NA S Outer membrane protein Omp28 MAG.T22.56_01854 153721.MYP_2617 1.1e-213 750.0 Cytophagia ko:K02014,ko:K16087 ko00000,ko02000 1.B.14,1.B.14.2 Bacteria 47M16@768503,4NFZY@976,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T22.56_01855 1267211.KI669560_gene1047 4.1e-54 218.0 Sphingobacteriia lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1IQPW@117747,4NEZN@976,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins MAG.T22.56_01856 485918.Cpin_7242 3e-12 77.8 Sphingobacteriia zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 1ITBU@117747,4NSA5@976,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division MAG.T22.56_01857 485918.Cpin_2195 8.5e-31 142.5 Sphingobacteriia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1IXWG@117747,4NJQN@976,COG3291@1,COG3291@2 NA|NA|NA M PKD domain containing protein MAG.T22.56_01858 1538644.KO02_19820 7.1e-122 443.7 Sphingobacteriia glt Bacteria 1IREF@117747,4NFKH@976,COG0069@1,COG0069@2 NA|NA|NA E Belongs to the glutamate synthase family MAG.T22.56_01859 485918.Cpin_7065 8.2e-29 133.3 Sphingobacteriia rnk ko:K03624,ko:K06140 ko00000,ko03000,ko03021 Bacteria 1ITY1@117747,4NW1R@976,COG0782@1,COG0782@2 NA|NA|NA J transcription elongation factor GreA MAG.T22.56_01862 743722.Sph21_2758 1.5e-73 282.7 Sphingobacteriia dedA 3.6.1.27 ko:K03975,ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1J08G@117747,4NMBP@976,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T22.56_01863 1121481.AUAS01000006_gene724 1.8e-121 443.0 Cytophagia Bacteria 47KN4@768503,4NDZK@976,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family MAG.T22.56_01864 743722.Sph21_2563 8.4e-20 102.8 Sphingobacteriia ko:K09981 ko00000 Bacteria 1IUHP@117747,4NWSY@976,COG3809@1,COG3809@2 NA|NA|NA S Transcription factor zinc-finger MAG.T22.56_01865 485918.Cpin_3339 0.0 1529.2 Sphingobacteriia ko:K03296,ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1IR3K@117747,4NDZG@976,COG0841@1,COG0841@2,COG1538@1,COG1538@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.56_01866 700598.Niako_5685 0.0 1712.6 Sphingobacteriia nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1IRF8@117747,4NEHQ@976,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen MAG.T22.56_01867 485917.Phep_1451 6.3e-28 130.6 Sphingobacteriia greA ko:K03624 ko00000,ko03021 Bacteria 1ITI1@117747,4NQAD@976,COG0782@1,COG0782@2 NA|NA|NA K Transcription elongation factor MAG.T22.56_01868 1406840.Q763_12715 1.2e-124 453.8 Flavobacterium Bacteria 1IKCE@117743,2DBTS@1,2NY7R@237,2ZB0P@2,4NGP7@976 NA|NA|NA S Domain of unknown function (DUF4397) MAG.T22.56_01869 1270196.JCKI01000008_gene1617 1.6e-43 183.7 Sphingobacteriia Bacteria 1IYN9@117747,2DMVN@1,32TYQ@2,4NSRQ@976 NA|NA|NA S Protein of unknown function (DUF3298) MAG.T22.56_01870 497965.Cyan7822_3696 6.3e-123 448.0 Bacteria 1.17.99.1 ko:K05797 ko00623,ko01100,ko01120,map00623,map01100,map01120 R02675,R11194 RC00769 ko00000,ko00001,ko01000 Bacteria COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidase domain protein MAG.T22.56_01871 1434325.AZQN01000007_gene3172 8.5e-64 250.4 Cytophagia Bacteria 28IFK@1,2Z8HB@2,47NVI@768503,4NH1P@976 NA|NA|NA MAG.T22.56_01873 1550091.JROE01000031_gene4209 7.3e-56 223.4 Sphingobacteriia Bacteria 1ISQ7@117747,4NP14@976,COG3437@1,COG3437@2 NA|NA|NA T cheY-homologous receiver domain MAG.T22.56_01874 1121904.ARBP01000005_gene4622 3.8e-65 255.0 Cytophagia lgtF ko:K12984 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 Bacteria 47XHY@768503,4NGYU@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.56_01875 1121324.CLIT_4c01720 2.7e-86 325.5 Clostridia rluF GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,248UG@186801,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T22.56_01876 269798.CHU_0286 7.4e-23 113.6 Cytophagia Bacteria 29WC5@1,30HXS@2,47SJP@768503,4NNWN@976 NA|NA|NA MAG.T22.56_01877 558152.IQ37_11810 3.1e-55 221.5 Flavobacteriia Bacteria 1I8KU@117743,2AYX9@1,31R2Z@2,4NNS4@976 NA|NA|NA S DinB superfamily MAG.T22.56_01883 929703.KE386491_gene3794 3.2e-44 186.4 Cytophagia Bacteria 47MXC@768503,4NEVQ@976,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T22.56_01884 1279009.ADICEAN_01130 4.5e-46 191.8 Cytophagia ko:K07011 ko00000 Bacteria 47KWP@768503,4NFW5@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 MAG.T22.56_01885 700598.Niako_3018 8.6e-56 223.8 Sphingobacteriia Bacteria 1IYVG@117747,4PNUQ@976,COG2227@1,COG2227@2 NA|NA|NA H PFAM Methyltransferase type 11 MAG.T22.56_01886 700598.Niako_3020 5.9e-25 120.6 Sphingobacteriia Bacteria 1IZ0H@117747,4NKMR@976,COG1216@1,COG1216@2 NA|NA|NA S involved in cell wall biogenesis MAG.T22.56_01891 290317.Cpha266_1872 1.9e-14 86.3 Chlorobi dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 ko:K03686 ko00000,ko03029,ko03110 Bacteria 1FD9R@1090,COG0484@1,COG0484@2 NA|NA|NA J ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T22.56_01892 1453505.JASY01000001_gene3485 1.1e-10 75.1 Flavobacterium Bacteria 1HZTN@117743,2NXZV@237,4NJHN@976,COG1520@1,COG1520@2 NA|NA|NA L Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.56_01896 485918.Cpin_3108 0.0 1180.2 Sphingobacteriia parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1IQ9E@117747,4NERI@976,COG0188@1,COG0188@2 NA|NA|NA L COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit MAG.T22.56_01897 929713.NIASO_05450 6.4e-68 263.8 Sphingobacteriia yqdE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03617,ko:K08999 ko00000 Bacteria 1IRH8@117747,4NGSW@976,COG1259@1,COG1259@2 NA|NA|NA S PFAM Uncharacterised ACR, COG1259 MAG.T22.56_01898 1227739.Hsw_3790 3.1e-46 193.0 Cytophagia Bacteria 47JD6@768503,4NGRJ@976,COG3227@1,COG3227@2,COG3291@1,COG3291@2 NA|NA|NA O PFAM Pregnancy-associated plasma protein-A MAG.T22.56_01899 485918.Cpin_4713 1.5e-158 565.8 Sphingobacteriia mqnE GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_3391 Bacteria 1IPM7@117747,4NGDN@976,COG1060@1,COG1060@2 NA|NA|NA H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate MAG.T22.56_01900 977880.RALTA_A2384 5.9e-26 125.6 Burkholderiaceae Bacteria 1KAWW@119060,1N5XI@1224,2B90Y@1,2VZG0@28216,322BP@2 NA|NA|NA MAG.T22.56_01901 700598.Niako_0298 2e-27 128.3 Sphingobacteriia Bacteria 1J0M5@117747,4PKN6@976,COG0477@1,COG0477@2 NA|NA|NA EGP PFAM Major Facilitator Superfamily MAG.T22.56_01902 700598.Niako_1997 5.7e-81 308.5 Sphingobacteriia Bacteria 1IP2Z@117747,4NFS7@976,COG2067@1,COG2067@2 NA|NA|NA I membrane protein involved in aromatic hydrocarbon degradation MAG.T22.56_01904 1122605.KB893626_gene2714 5.6e-227 793.5 Sphingobacteriia proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1IQ4M@117747,4NEAF@976,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) MAG.T22.56_01905 1229487.AMYW01000002_gene1505 1.3e-17 96.3 Flavobacterium Bacteria 1I4Z6@117743,2E6Q3@1,2NWBJ@237,331AC@2,4NUP2@976 NA|NA|NA MAG.T22.56_01906 1034807.FBFL15_0698 1.4e-24 120.6 Flavobacterium ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 1I8F6@117743,2P0DN@237,4NV9S@976,COG5295@1,COG5295@2 NA|NA|NA UW Hep Hag repeat protein MAG.T22.56_01907 1313421.JHBV01000138_gene1207 8e-08 63.9 Sphingobacteriia Bacteria 1IU7V@117747,2DPQ3@1,332XU@2,4NX0W@976 NA|NA|NA MAG.T22.56_01908 1313421.JHBV01000026_gene395 4.9e-115 421.0 Bacteroidetes pepA 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 4NDWT@976,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T22.56_01909 700598.Niako_6924 1.3e-119 436.4 Sphingobacteriia pdxA 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 Bacteria 1IP2F@117747,4NEUR@976,COG1995@1,COG1995@2 NA|NA|NA H Belongs to the PdxA family MAG.T22.56_01910 1122605.KB893646_gene232 3e-165 588.2 Sphingobacteriia ko:K07263 ko00000,ko01000,ko01002 Bacteria 1INSD@117747,4NEDZ@976,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 MAG.T22.56_01911 925409.KI911562_gene1482 5.3e-125 454.1 Sphingobacteriia fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IRN3@117747,4NF8Z@976,COG2070@1,COG2070@2 NA|NA|NA S 2-nitropropane dioxygenase MAG.T22.56_01912 485918.Cpin_4711 9.7e-37 161.8 Sphingobacteriia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1ISKM@117747,4NNVK@976,COG3291@1,COG3291@2 NA|NA|NA S C-terminal domain of CHU protein family MAG.T22.56_01913 714943.Mucpa_1196 3.2e-108 398.7 Sphingobacteriia Bacteria 1IQMR@117747,4NGZ9@976,COG4487@1,COG4487@2 NA|NA|NA S protein conserved in bacteria MAG.T22.56_01915 700598.Niako_1599 2.2e-162 578.6 Sphingobacteriia ntrX Bacteria 1IPCA@117747,4NE89@976,COG2204@1,COG2204@2 NA|NA|NA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains MAG.T22.56_01916 485918.Cpin_0616 9.2e-129 466.8 Sphingobacteriia dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1IP8C@117747,4NESB@976,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria MAG.T22.56_01917 700598.Niako_5730 0.0 1271.1 Sphingobacteriia alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1INPU@117747,4NFHW@976,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain MAG.T22.56_01918 714943.Mucpa_1977 1.2e-41 176.8 Bacteroidetes Bacteria 29XSJ@1,30JIE@2,4NPEJ@976 NA|NA|NA MAG.T22.56_01919 1121373.KB903627_gene2952 3.6e-40 171.8 Cytophagia ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 47KRB@768503,4NE80@976,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein protective antigen OMA87 MAG.T22.56_01920 45351.EDO26796 3e-141 508.1 Metazoa 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Metazoa 38CCH@33154,3BCCT@33208,COG0010@1,KOG2965@2759 NA|NA|NA E arginase activity MAG.T22.56_01922 925409.KI911562_gene2165 0.0 1220.7 Sphingobacteriia valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1IPEY@117747,4NETB@976,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner MAG.T22.56_01923 443143.GM18_2242 2.2e-76 292.7 Proteobacteria 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1R4XH@1224,COG2730@1,COG2730@2 NA|NA|NA G Belongs to the glycosyl hydrolase 5 (cellulase A) family MAG.T22.56_01924 1120963.KB894501_gene235 3.1e-42 178.3 Pseudoalteromonadaceae ada 2.1.1.63,3.2.2.21 ko:K00567,ko:K10778,ko:K13529,ko:K13530,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1N2YQ@1224,1RPR3@1236,2Q5DQ@267888,COG0350@1,COG0350@2,COG2169@1,COG2169@2 NA|NA|NA FL 6-O-methylguanine DNA methyltransferase, DNA binding domain MAG.T22.56_01925 485918.Cpin_2506 1.5e-16 92.4 Bacteria ko:K04786 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Bacteria COG3319@1,COG3319@2 NA|NA|NA Q amino acid activation for nonribosomal peptide biosynthetic process MAG.T22.56_01926 1123248.KB893386_gene1906 1e-42 179.5 Sphingobacteriia nosD ko:K07218 ko00000 Bacteria 1IRBN@117747,4NEGT@976,COG3420@1,COG3420@2 NA|NA|NA P PFAM Periplasmic copper-binding protein (NosD) MAG.T22.56_01927 1123248.KB893386_gene1905 5.3e-77 294.3 Sphingobacteriia nosF ko:K01990,ko:K19340 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 1IPBT@117747,4NG9T@976,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase component MAG.T22.56_01928 468059.AUHA01000007_gene2676 4.9e-65 254.6 Sphingobacteriia nosY ko:K01992,ko:K19341 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 1IPGQ@117747,4NGGR@976,COG1277@1,COG1277@2 NA|NA|NA S nitrous oxide MAG.T22.56_01929 700598.Niako_4173 5.1e-85 321.2 Sphingobacteriia scdA ko:K07322 ko00000 Bacteria 1IQS1@117747,4NE9M@976,COG2846@1,COG2846@2,COG4309@1,COG4309@2 NA|NA|NA D Di-iron-containing protein involved in the repair of iron-sulfur clusters MAG.T22.56_01930 1150600.ADIARSV_3474 2e-44 186.8 Sphingobacteriia Bacteria 1IRVC@117747,4NHY4@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_01931 641524.ADICYQ_4385 1.3e-41 176.0 Cytophagia Bacteria 47QPE@768503,4NQGU@976,COG1959@1,COG1959@2 NA|NA|NA K TIGRFAM Rrf2 family protein MAG.T22.56_01932 1089547.KB913013_gene4646 3.3e-39 168.3 Cytophagia Bacteria 47XS3@768503,4NMPI@976,COG2335@1,COG2335@2 NA|NA|NA M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. MAG.T22.56_01933 985255.APHJ01000039_gene91 1.3e-26 126.3 Gillisia Bacteria 1I24Y@117743,2P7N5@244698,4NP8M@976,COG5592@1,COG5592@2 NA|NA|NA S Hemerythrin HHE cation binding domain MAG.T22.56_01934 929556.Solca_0518 1.1e-120 440.3 Sphingobacteriia 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 1IP1A@117747,4NIGA@976,COG3278@1,COG3278@2 NA|NA|NA O Cytochrome C and Quinol oxidase polypeptide I MAG.T22.56_01935 929556.Solca_0519 3.1e-31 141.4 Sphingobacteriia ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 Bacteria 1IU8D@117747,4NQE3@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III MAG.T22.56_01936 485918.Cpin_0191 1.7e-179 636.0 Sphingobacteriia mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 Bacteria 1IQ2C@117747,4NE47@976,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding protein 2 MAG.T22.56_01937 485918.Cpin_0190 9.8e-114 417.2 Sphingobacteriia rodA ko:K05837 ko00000,ko03036 Bacteria 1INPB@117747,4NDZD@976,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T22.56_01938 1267211.KI669560_gene23 4.9e-70 271.2 Sphingobacteriia Bacteria 1IQ1J@117747,4NHW8@976,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase MAG.T22.56_01939 468059.AUHA01000006_gene2867 3.7e-17 94.7 Sphingobacteriia Bacteria 1ITXJ@117747,2DPE1@1,331PZ@2,4NV5C@976 NA|NA|NA MAG.T22.56_01941 700598.Niako_6880 1e-64 253.1 Sphingobacteriia rpoE ko:K03088 ko00000,ko03021 Bacteria 1IQKN@117747,4NMC0@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.56_01942 700598.Niako_4582 1.4e-104 386.3 Sphingobacteriia fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria 1IPT6@117747,4NE8U@976,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus MAG.T22.56_01943 1267211.KI669560_gene2071 1.4e-40 172.6 Sphingobacteriia aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 3.4.13.9,4.2.1.10 ko:K01271,ko:K03785,ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000,ko01002 iIT341.HP1038,iJN746.PP_0560 Bacteria 1ISBR@117747,4NNHU@976,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate MAG.T22.56_01944 1288963.ADIS_0694 9.4e-32 143.3 Cytophagia Bacteria 47RS5@768503,4NQ5T@976,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein MAG.T22.56_01945 485918.Cpin_1675 4.9e-54 218.0 Sphingobacteriia spoU 2.1.1.170,2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437,ko:K03501 ko00000,ko01000,ko03009,ko03016,ko03036 Bacteria 1IQKS@117747,4NG1U@976,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T22.56_01946 1123277.KB893217_gene4459 1.2e-07 63.9 Cytophagia Bacteria 47SPM@768503,4NYC2@976,COG2913@1,COG2913@2 NA|NA|NA J Domain of unknown function (DUF4476) MAG.T22.56_01947 485918.Cpin_1850 1.8e-46 192.6 Sphingobacteriia ybjG 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1ISC5@117747,4NNVQ@976,COG0671@1,COG0671@2 NA|NA|NA I Phosphoesterase PA-phosphatase related MAG.T22.56_01948 762903.Pedsa_2075 7.7e-60 237.3 Sphingobacteriia yccK Bacteria 1IPHK@117747,4NFKM@976,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase MAG.T22.56_01950 929713.NIASO_12765 2.7e-32 145.6 Bacteria Bacteria COG3063@1,COG3063@2 NA|NA|NA NU photosynthesis MAG.T22.56_01953 929556.Solca_1335 2.2e-68 265.4 Sphingobacteriia Bacteria 1IY10@117747,4NNFN@976,COG3863@1,COG3863@2 NA|NA|NA S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family MAG.T22.56_01954 391625.PPSIR1_05583 4.6e-26 127.1 Myxococcales 3.1.3.64 ko:K07004,ko:K21302 ko00562,ko01100,ko05152,map00562,map01100,map05152 ko00000,ko00001,ko01000 Bacteria 1Q6DC@1224,2WYJ7@28221,2Z34H@29,432XR@68525,COG3227@1,COG3227@2 NA|NA|NA E Zinc metalloprotease (Elastase) MAG.T22.56_01956 236814.IX39_01785 2.2e-73 282.3 Chryseobacterium ko:K09797 ko00000 Bacteria 1HZJF@117743,3ZP79@59732,4NI76@976,COG2859@1,COG2859@2 NA|NA|NA S Protein of unknown function (DUF541) MAG.T22.56_01958 929703.KE386491_gene3345 1.6e-22 113.2 Cytophagia Bacteria 2D6MI@1,32TMJ@2,47Q9V@768503,4NPMS@976 NA|NA|NA S PAP2 superfamily C-terminal MAG.T22.56_01959 391596.PBAL39_03055 1.2e-96 359.8 Sphingobacteriia motB ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1IR4D@117747,4NF2Y@976,COG1360@1,COG1360@2 NA|NA|NA N OmpA MotB domain protein MAG.T22.56_01960 700598.Niako_0829 1e-116 426.8 Sphingobacteriia ko:K13292 ko00000,ko01000 Bacteria 1INRB@117747,4NGSG@976,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T22.56_01961 1267211.KI669560_gene1574 3.4e-94 351.7 Sphingobacteriia udp 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1INVP@117747,4NG5S@976,COG2820@1,COG2820@2 NA|NA|NA F phosphorylase MAG.T22.56_01964 485918.Cpin_4667 1e-262 913.3 Sphingobacteriia Bacteria 1IPDR@117747,4PKJX@976,COG1807@1,COG1807@2 NA|NA|NA M Protein of unknown function (DUF2723) MAG.T22.56_01965 929713.NIASO_16345 3.8e-14 84.7 Sphingobacteriia Bacteria 1ITIX@117747,2DRKN@1,33C6H@2,4NZAT@976 NA|NA|NA MAG.T22.56_01977 945713.IALB_3197 8.6e-45 186.4 Bacteria ko:K07032 ko00000 Bacteria COG3607@1,COG3607@2 NA|NA|NA MAG.T22.56_01978 929556.Solca_3684 1.1e-130 473.0 Sphingobacteriia Bacteria 1IP57@117747,4NGSR@976,COG4977@1,COG4977@2 NA|NA|NA K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain MAG.T22.56_01979 755732.Fluta_3177 2.5e-61 242.3 Cryomorphaceae Bacteria 1IGD0@117743,2DBUB@1,2PBPS@246874,2ZB53@2,4NMWS@976 NA|NA|NA MAG.T22.56_01980 926549.KI421517_gene1617 2.1e-90 339.3 Cytophagia 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 47K55@768503,4NE4P@976,COG1858@1,COG1858@2 NA|NA|NA C cytochrome c peroxidase MAG.T22.56_01981 926562.Oweho_3447 8e-74 284.3 Flavobacteriia mauG 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1HXUF@117743,4NE4P@976,COG1858@1,COG1858@2 NA|NA|NA C cytochrome C peroxidase MAG.T22.56_01982 504472.Slin_0596 6.5e-82 311.2 Cytophagia Bacteria 2ZA6T@2,47PN1@768503,4NGZ2@976,arCOG10456@1 NA|NA|NA MAG.T22.56_01983 1123248.KB893322_gene568 1.8e-15 90.5 Sphingobacteriia Bacteria 1IV4S@117747,4NDZC@976,COG1361@1,COG1361@2,COG3291@1,COG3291@2,COG4386@1,COG4386@2 NA|NA|NA M Immunoglobulin MAG.T22.56_01984 273121.WS0046 4.3e-121 441.8 Epsilonproteobacteria asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4E@1224,2YND5@29547,42MEI@68525,COG0367@1,COG0367@2 NA|NA|NA E asparagine MAG.T22.56_01985 1267533.KB906738_gene2154 1.6e-17 97.4 Acidobacteriia Bacteria 2JIV5@204432,3Y2VM@57723,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 MAG.T22.56_01986 1227739.Hsw_0816 3e-69 269.2 Cytophagia pglJ GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.291 ko:K17248 ko00000,ko01000,ko01003 GT4 Bacteria 47SF0@768503,4NQKE@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T22.56_01987 1227739.Hsw_0817 6.3e-66 258.1 Cytophagia cps2I Bacteria 47UKE@768503,4PAVB@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_01988 1356852.N008_03895 9.2e-102 377.1 Cytophagia ko:K07011 ko00000 Bacteria 47N47@768503,4NJ6W@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.56_01989 1122605.KB893647_gene419 1.8e-102 379.4 Bacteroidetes Bacteria 28ICP@1,2Z8EZ@2,4NKKI@976 NA|NA|NA MAG.T22.56_01990 1349785.BAUG01000066_gene2624 1e-09 71.2 Flavobacteriia Bacteria 1I6XH@117743,2BUJI@1,32PVZ@2,4NYYN@976 NA|NA|NA MAG.T22.56_01991 515635.Dtur_0436 2.6e-25 123.2 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process MAG.T22.56_01992 755732.Fluta_2429 9.6e-17 95.5 Bacteria Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T22.56_01994 525257.HMPREF0204_12757 1.2e-55 222.6 Chryseobacterium ko:K04750 ko00000 Bacteria 1I2AQ@117743,3ZPQ0@59732,4NQD7@976,COG2764@1,COG2764@2 NA|NA|NA S Glyoxalase MAG.T22.56_01995 153721.MYP_3109 3.9e-48 197.6 Cytophagia Bacteria 47RED@768503,4NQGY@976,COG4898@1,COG4898@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.56_01996 945713.IALB_1082 1.4e-15 91.3 Bacteria 3.1.3.1,3.1.3.5,3.1.3.8,3.6.1.45 ko:K01077,ko:K01083,ko:K07004,ko:K11751 ko00230,ko00240,ko00562,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00562,map00730,map00760,map00790,map01100,map01110,map02020 M00126 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R03371,R04620 RC00017,RC00078 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.56_01998 313606.M23134_05227 9.4e-17 94.4 Cytophagia Bacteria 47KZM@768503,4PM4C@976,COG1404@1,COG1404@2,COG4733@1,COG4733@2 NA|NA|NA O Subtilase family MAG.T22.56_01999 1035197.HMPREF9999_01416 6.7e-66 257.3 Alloprevotella Bacteria 1WCSI@1283313,2FNZV@200643,4NF1I@976,COG0745@1,COG0745@2 NA|NA|NA K Psort location Cytoplasmic, score 9.97 MAG.T22.56_02000 1267211.KI669560_gene1180 6.2e-59 235.3 Sphingobacteriia rprX 2.7.13.3 ko:K02484,ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1J0U6@117747,4PKBV@976,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_02001 1121285.AUFK01000009_gene788 9.2e-10 70.9 Chryseobacterium Bacteria 1HZTN@117743,3ZR9J@59732,4NJHN@976,COG1520@1,COG1520@2 NA|NA|NA S Leucine-rich repeat (LRR) protein MAG.T22.56_02002 1406840.Q763_15680 6.3e-32 143.3 Flavobacteriia Bacteria 1I4K8@117743,4NTKH@976,COG0477@1,COG2814@2 NA|NA|NA EGP Domain of unknown function (DUF3817) MAG.T22.56_02003 485918.Cpin_5476 1e-55 223.4 Sphingobacteriia Bacteria 1IT3A@117747,4NKAD@976,COG2197@1,COG2197@2 NA|NA|NA K Two component transcriptional regulator, LuxR family MAG.T22.56_02004 1123248.KB893324_gene1762 2.8e-36 159.1 Sphingobacteriia Bacteria 1IXIC@117747,4NN4R@976,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.56_02018 537007.BLAHAN_04212 2.8e-35 156.8 Blautia 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 ko00000,ko01000,ko02048 Bacteria 1TR56@1239,248NR@186801,3Y19M@572511,COG0863@1,COG0863@2 NA|NA|NA L DNA methylase MAG.T22.56_02021 1123248.KB893317_gene4363 1.4e-59 237.3 Sphingobacteriia Bacteria 1ISHB@117747,4NDZJ@976,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase SAM-like domain MAG.T22.56_02022 985255.APHJ01000039_gene144 4.8e-19 101.3 Gillisia ycgE ko:K19591,ko:K22491 M00769 ko00000,ko00002,ko01504,ko03000 Bacteria 1I2UP@117743,2P6TF@244698,4NSBD@976,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance MAG.T22.56_02023 1123248.KB893348_gene235 1.2e-176 625.9 Sphingobacteriia mqnC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQI2@117747,4NGTU@976,COG1060@1,COG1060@2 NA|NA|NA H Radical SAM MAG.T22.56_02024 1122604.JONR01000001_gene1803 3.2e-61 241.9 Xanthomonadales yfcA ko:K07090 ko00000 Bacteria 1MXNM@1224,1RRH4@1236,1X686@135614,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein MAG.T22.56_02025 485918.Cpin_0778 1.2e-123 449.9 Sphingobacteriia ybdL GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.6.1.17,2.6.1.88 ko:K14267,ko:K14287 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475,R08618 RC00006,RC00025 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0858c Bacteria 1IP0R@117747,4NES3@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.56_02026 485918.Cpin_0777 4.4e-144 517.7 Sphingobacteriia manC 2.7.7.13,5.3.1.8,5.4.2.8 ko:K00971,ko:K01840,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01818,R01819 RC00002,RC00376,RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1INM4@117747,4NE1Y@976,COG0836@1,COG0836@2 NA|NA|NA M mannose-1-phosphate guanylyltransferase MAG.T22.56_02027 700598.Niako_6306 9.5e-85 319.7 Sphingobacteriia nifU Bacteria 1IQ4T@117747,4NG0Q@976,COG0694@1,COG0694@2 NA|NA|NA O PFAM Scaffold protein Nfu NifU N terminal MAG.T22.56_02029 485918.Cpin_3371 8.6e-94 350.9 Sphingobacteriia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IR94@117747,4NECN@976,COG0577@1,COG0577@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, permease component MAG.T22.56_02030 929713.NIASO_00860 9e-36 156.8 Sphingobacteriia pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1ISDB@117747,4NNRI@976,COG2065@1,COG2065@2 NA|NA|NA F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase MAG.T22.56_02031 1267211.KI669560_gene2330 4.4e-108 397.9 Sphingobacteriia ybiK 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 1IQI3@117747,4NF1U@976,COG1446@1,COG1446@2 NA|NA|NA E Asparaginase MAG.T22.56_02033 485918.Cpin_6851 6.1e-86 324.3 Sphingobacteriia darA Bacteria 1ISM3@117747,4NHTB@976,COG0716@1,COG0716@2 NA|NA|NA C Dialkylrecorsinol condensing enzyme DarA MAG.T22.56_02034 485918.Cpin_6850 8.7e-127 460.3 Sphingobacteriia darB 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IPV9@117747,4NE5Q@976,COG0332@1,COG0332@2 NA|NA|NA I PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III MAG.T22.56_02036 1144313.PMI10_01181 3.2e-44 184.9 Flavobacterium 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1I1XF@117743,2NWAI@237,4NNNG@976,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase MAG.T22.56_02038 1121875.KB907547_gene3395 3.4e-26 124.4 Flavobacteriia Bacteria 1I2VI@117743,2AFVV@1,315YK@2,4NQ4S@976 NA|NA|NA MAG.T22.56_02039 1189612.A33Q_1405 1.6e-88 333.2 Bacteroidetes Bacteria 4NIEB@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.56_02040 525373.HMPREF0766_13639 3.3e-29 135.2 Sphingobacteriia Bacteria 1J00N@117747,4NJCE@976,COG0664@1,COG0664@2 NA|NA|NA T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein MAG.T22.56_02043 509635.N824_21890 1e-42 180.3 Sphingobacteriia Bacteria 1ISUG@117747,4NS2T@976,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T22.56_02044 929556.Solca_0570 3.2e-25 122.1 Sphingobacteriia Bacteria 1J0DQ@117747,2D0I5@1,32T8N@2,4NSMU@976 NA|NA|NA S Four helix bundle sensory module for signal transduction MAG.T22.56_02045 1185876.BN8_02012 2.8e-09 68.6 Bacteria Bacteria 2F4UR@1,33XH2@2 NA|NA|NA MAG.T22.56_02046 485918.Cpin_0874 3e-89 335.5 Sphingobacteriia yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1IQGD@117747,4NENX@976,COG1774@1,COG1774@2 NA|NA|NA S PFAM PSP1 C-terminal conserved region MAG.T22.56_02047 1041826.FCOL_11900 1.9e-91 343.2 Flavobacterium aaxA ko:K16080 ko00000,ko02000 1.B.4.2.2 Bacteria 1I7GH@117743,2NVH9@237,4NHN1@976,COG3659@1,COG3659@2 NA|NA|NA M Carbohydrate-selective porin, OprB family MAG.T22.56_02048 485918.Cpin_0775 0.0 1077.0 Sphingobacteriia recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1IQ8E@117747,4NEB4@976,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ MAG.T22.56_02049 1123300.AUIN01000009_gene303 1.1e-36 159.8 Bacilli folK 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6PR@1239,4HIMG@91061,COG0801@1,COG0801@2 NA|NA|NA H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase MAG.T22.56_02051 485918.Cpin_0242 6e-179 633.6 Sphingobacteriia glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECIAI39_1322.ECIAI39_0637 Bacteria 1IQC9@117747,4NFCC@976,COG0008@1,COG0008@2 NA|NA|NA J Glutaminyl-tRNA synthetase MAG.T22.56_02052 929556.Solca_2903 5.2e-30 137.5 Bacteria Bacteria COG1257@1,COG1257@2 NA|NA|NA I hydroxymethylglutaryl-CoA reductase (NADPH) activity MAG.T22.56_02053 485918.Cpin_0942 4.5e-46 190.7 Sphingobacteriia tdcF 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 1IT12@117747,4NQ8M@976,COG0251@1,COG0251@2 NA|NA|NA J endoribonuclease L-PSP MAG.T22.56_02054 1121129.KB903360_gene3315 8.9e-26 124.0 Porphyromonadaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 ko:K14742 ko00000,ko03016 Bacteria 22WRV@171551,2FPYK@200643,4NDUR@976,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ MAG.T22.56_02055 485918.Cpin_0945 1.8e-38 165.2 Sphingobacteriia bigR ko:K03892,ko:K07721,ko:K22042,ko:K22491 ko00000,ko03000 Bacteria 1IYKV@117747,4P4RQ@976,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T22.56_02056 700598.Niako_6200 3e-86 324.7 Sphingobacteriia paaY GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009437,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0044237,GO:0071704,GO:0097164,GO:1901564 ko:K02617,ko:K08279 ko00000 Bacteria 1IVF8@117747,4NG5P@976,COG0663@1,COG0663@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase MAG.T22.56_02058 485918.Cpin_1055 1.1e-13 81.6 Sphingobacteriia rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IU87@117747,4NUTV@976,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family MAG.T22.56_02059 485918.Cpin_7021 1.7e-30 140.6 Sphingobacteriia Bacteria 1IPR2@117747,4NIEU@976,COG0457@1,COG0457@2 NA|NA|NA NU PFAM Tetratricopeptide MAG.T22.56_02060 1267211.KI669560_gene2446 1.8e-63 249.2 Sphingobacteriia exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 1IQAP@117747,4NFIX@976,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel MAG.T22.56_02061 1123248.KB893323_gene1604 6.7e-48 196.8 Sphingobacteriia slyD 5.2.1.8 ko:K01802,ko:K03774,ko:K03775 ko00000,ko01000,ko03110 Bacteria 1ITWU@117747,4NM29@976,COG1047@1,COG1047@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.56_02062 1313301.AUGC01000016_gene864 7.5e-116 424.1 Bacteroidetes Bacteria 4NEXD@976,COG3876@1,COG3876@2 NA|NA|NA S PFAM uncharacterised conserved protein UCP016719 MAG.T22.56_02065 269798.CHU_0938 1.3e-117 431.8 Cytophagia Bacteria 47Q36@768503,4NNUN@976,COG1520@1,COG1520@2 NA|NA|NA G Belongs to the glycosyl hydrolase 8 (cellulase D) family MAG.T22.56_02066 485918.Cpin_6900 9.8e-69 267.3 Sphingobacteriia ko:K06076 ko00000,ko02000 1.B.9 Bacteria 1IQ3Y@117747,4NIU4@976,COG2067@1,COG2067@2 NA|NA|NA I protein CHP03519, membrane, Bacteroidetes MAG.T22.56_02067 700598.Niako_5493 1.7e-43 182.6 Sphingobacteriia 3.2.1.91 ko:K19668 ko00500,ko01100,ko02020,map00500,map01100,map02020 R02886,R11308 RC00799 ko00000,ko00001,ko01000 GH6 Bacteria 1IW61@117747,4NPDM@976,COG3291@1,COG3291@2 NA|NA|NA G PFAM PKD domain MAG.T22.56_02068 1288963.ADIS_2124 3.7e-07 62.8 Cytophagia Bacteria 47KAA@768503,4NE5D@976,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T22.56_02070 1237149.C900_00612 2.8e-15 89.7 Cytophagia ywmD ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 47MRQ@768503,4NJF1@976,COG2304@1,COG2304@2 NA|NA|NA S PFAM von Willebrand factor type A domain MAG.T22.56_02071 1313421.JHBV01000006_gene376 1.6e-19 103.6 Sphingobacteriia Bacteria 1IYAK@117747,28MPU@1,2ZAYW@2,4NXA9@976 NA|NA|NA MAG.T22.56_02075 1408813.AYMG01000007_gene4346 1.4e-251 875.9 Sphingobacteriia mca ko:K22136 ko00000 Bacteria 1IPTV@117747,4NE9K@976,COG2120@1,COG2120@2 NA|NA|NA G LmbE family MAG.T22.56_02076 929562.Emtol_1681 6.5e-71 274.2 Cytophagia Bacteria 47PGN@768503,4P246@976,COG0457@1,COG0457@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.56_02077 485918.Cpin_3718 3.1e-20 104.4 Bacteroidetes M1-594 Bacteria 4NVNG@976,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein MAG.T22.56_02078 485918.Cpin_2230 7e-99 367.1 Sphingobacteriia pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 1IQ9S@117747,4NE12@976,COG0284@1,COG0284@2 NA|NA|NA F Orotidine 5''-phosphate decarboxylase MAG.T22.56_02079 45351.EDO26062 6.5e-108 397.1 Metazoa Metazoa 38DZE@33154,3BA0D@33208,COG1028@1,KOG0725@2759 NA|NA|NA Q Hydroxysteroid dehydrogenase-like protein MAG.T22.56_02080 1124780.ANNU01000074_gene731 6.4e-56 223.8 Cytophagia Bacteria 47P9R@768503,4NNMD@976,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family MAG.T22.56_02081 1267211.KI669560_gene655 2.5e-40 171.8 Sphingobacteriia Bacteria 1IT21@117747,4NQ5T@976,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator MAG.T22.56_02084 485918.Cpin_1208 1.3e-14 86.3 Sphingobacteriia Bacteria 1IUDD@117747,2AVDM@1,31M58@2,4NUN6@976 NA|NA|NA S Domain of unknown function (DUF4293) MAG.T22.56_02085 1267211.KI669560_gene718 6.6e-168 597.0 Sphingobacteriia serS 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1IQMK@117747,4NED6@976,COG0172@1,COG0172@2 NA|NA|NA J seryl-tRNA synthetase MAG.T22.56_02086 485918.Cpin_0433 5e-150 537.3 Sphingobacteriia moxR ko:K03924 ko00000,ko01000 Bacteria 1IPXJ@117747,4NDVZ@976,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T22.56_02087 485918.Cpin_0434 4.5e-28 130.6 Sphingobacteriia Bacteria 1ISQF@117747,29D8R@1,3006P@2,4NNGD@976 NA|NA|NA MAG.T22.56_02088 1121286.AUMT01000001_gene459 2.7e-64 253.4 Chryseobacterium ko:K12057 ko00000,ko02044 3.A.7.11.1 Bacteria 1ICV8@117743,3ZQ83@59732,4NT9C@976,COG0526@1,COG0526@2 NA|NA|NA CO Outer membrane protein Omp28 MAG.T22.56_02090 485917.Phep_0043 2.6e-67 261.9 Sphingobacteriia psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1INZC@117747,4NFU1@976,COG0688@1,COG0688@2 NA|NA|NA I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) MAG.T22.56_02091 925409.KI911562_gene521 3e-44 185.7 Sphingobacteriia cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 ko:K00981,ko:K07098,ko:K19664 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799,R08966 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1J13D@117747,4PPXI@976,COG0575@1,COG0575@2 NA|NA|NA I Cytidylyltransferase family MAG.T22.56_02092 700598.Niako_6618 2.5e-18 99.8 Sphingobacteriia ko:K07052 ko00000 Bacteria 1ITS1@117747,4NHE1@976,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T22.56_02093 485918.Cpin_0376 6.3e-287 993.0 Sphingobacteriia dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 Bacteria 1INUN@117747,4NDY5@976,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) MAG.T22.56_02095 1089547.KB913013_gene2172 5.5e-29 134.0 Cytophagia Bacteria 47QJ6@768503,4NIXX@976,COG4232@1,COG4232@2 NA|NA|NA CO Protein of unknown function, DUF255 MAG.T22.56_02099 1123057.P872_12450 8.1e-29 134.4 Cytophagia Bacteria 47N8W@768503,4PM1Y@976,COG0745@1,COG0745@2 NA|NA|NA T Response regulator receiver domain MAG.T22.56_02101 925409.KI911562_gene2837 4e-92 345.1 Bacteria ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria COG2333@1,COG2333@2 NA|NA|NA N competence protein COMEC MAG.T22.56_02102 925409.KI911562_gene2838 5.3e-19 101.3 Bacteria Bacteria 2EMZW@1,33FN2@2 NA|NA|NA MAG.T22.56_02104 700598.Niako_6994 8.9e-245 854.0 Sphingobacteriia porU Bacteria 1IW9T@117747,4NDY7@976,COG1572@1,COG1572@2 NA|NA|NA S Peptidase family C25 MAG.T22.56_02105 485918.Cpin_1181 3.6e-144 518.5 Sphingobacteriia pkn1 Bacteria 1IQK8@117747,4NE51@976,COG1262@1,COG1262@2 NA|NA|NA S gliding motility-associated lipoprotein GldJ MAG.T22.56_02106 1267211.KI669560_gene1987 2.2e-21 109.0 Sphingobacteriia aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1ITC4@117747,4NQ73@976,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate MAG.T22.56_02107 925409.KI911562_gene2253 4.6e-105 388.3 Sphingobacteriia cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1INYU@117747,4NDVV@976,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family MAG.T22.56_02108 485918.Cpin_2329 4.2e-47 194.1 Sphingobacteriia ybgC ko:K07107 ko00000,ko01000 Bacteria 1IT5E@117747,4NQGW@976,COG0824@1,COG0824@2 NA|NA|NA S thioesterase MAG.T22.56_02109 485918.Cpin_6941 8.1e-84 317.0 Sphingobacteriia ydfG 1.1.1.276 ko:K05886 ko00000,ko01000 Bacteria 1INN2@117747,4NE1R@976,COG4221@1,COG4221@2 NA|NA|NA NU Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.56_02110 485918.Cpin_6940 1.8e-103 383.6 Sphingobacteriia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1IXKI@117747,4NICC@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain containing protein MAG.T22.56_02111 485918.Cpin_6938 5.1e-52 211.5 Sphingobacteriia yfbB Bacteria 1IXNU@117747,4NHA9@976,COG2267@1,COG2267@2 NA|NA|NA I Ndr family MAG.T22.56_02112 1107311.Q767_06910 9.2e-20 103.2 Flavobacterium yvaZ ko:K06889 ko00000 Bacteria 1I1PF@117743,2NU47@237,4NNCF@976,COG5658@1,COG5658@2 NA|NA|NA S Protein of unknown function (DUF1648) MAG.T22.56_02113 1107311.Q767_03030 2.7e-101 375.9 Flavobacterium ko:K06889 ko00000 Bacteria 1HWSK@117743,2NUEG@237,4NFRN@976,COG1073@1,COG1073@2 NA|NA|NA S BAAT / Acyl-CoA thioester hydrolase C terminal MAG.T22.56_02114 485918.Cpin_1227 6.1e-220 770.4 Sphingobacteriia MdlB ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1IQFU@117747,4NEAG@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T22.56_02115 485918.Cpin_5492 5.7e-168 597.0 Sphingobacteriia prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1IP7G@117747,4NEN1@976,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA MAG.T22.56_02116 1379698.RBG1_1C00001G0702 1.3e-34 153.7 Bacteria Bacteria COG3586@1,COG3586@2 NA|NA|NA L endonuclease activity MAG.T22.56_02117 1122621.ATZA01000007_gene800 4.3e-38 164.5 Sphingobacteriia Bacteria 1ITAX@117747,4NSQN@976,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein MAG.T22.56_02119 153721.MYP_1941 1.6e-92 345.9 Cytophagia 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 47KCT@768503,4NF20@976,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T22.56_02120 714943.Mucpa_4880 6.3e-92 344.7 Sphingobacteriia Bacteria 1IQST@117747,4NK1I@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.56_02121 1122176.KB903587_gene4484 5.5e-157 561.2 Sphingobacteriia 3.4.11.10 ko:K05994 ko00000,ko01000,ko01002 Bacteria 1IPRF@117747,4NENF@976,COG2234@1,COG2234@2 NA|NA|NA S Peptidase family M28 MAG.T22.56_02125 485918.Cpin_1670 7.3e-117 426.8 Sphingobacteriia yitD 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPYS@117747,4NEHT@976,COG1809@1,COG1809@2 NA|NA|NA S PFAM (2R)-phospho-3-sulfolactate synthase ComA MAG.T22.56_02126 485918.Cpin_1671 5e-75 287.7 Sphingobacteriia aroE 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPMJ@117747,4NEBJ@976,COG0169@1,COG0169@2 NA|NA|NA E PFAM Shikimate dehydrogenase substrate binding MAG.T22.56_02127 485918.Cpin_1672 9.4e-88 330.1 Sphingobacteriia Bacteria 1IW68@117747,4NJ5I@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T22.56_02128 1313301.AUGC01000006_gene147 1.8e-110 406.0 Bacteroidetes aroF 2.5.1.54,5.4.99.5 ko:K03856,ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 4NDU4@976,COG2876@1,COG2876@2 NA|NA|NA E 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase MAG.T22.56_02129 929713.NIASO_18205 4.9e-72 277.7 Sphingobacteriia truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 1IPMS@117747,4NESK@976,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs MAG.T22.56_02130 1313421.JHBV01000041_gene3558 3.6e-32 144.4 Bacteroidetes Bacteria 4NNJS@976,COG0454@1,COG0456@2 NA|NA|NA K gnat family MAG.T22.56_02131 1123288.SOV_5c03000 1.1e-42 179.5 Negativicutes 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYP1@1239,4H1V4@909932,COG0289@1,COG0289@2 NA|NA|NA E Dihydrodipicolinate reductase, C-terminus MAG.T22.56_02132 485918.Cpin_0545 8.4e-164 583.6 Sphingobacteriia Bacteria 1IQJT@117747,4NDUF@976,COG0534@1,COG0534@2 NA|NA|NA V Mate efflux family protein MAG.T22.56_02133 714943.Mucpa_4875 3.6e-103 382.5 Sphingobacteriia Bacteria 1J0UU@117747,4NJVF@976,COG0642@1,COG0642@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_02135 925409.KI911562_gene2438 6.3e-218 763.5 Sphingobacteriia pruA 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 Bacteria 1IWY5@117747,4NFTW@976,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T22.56_02136 1123248.KB893319_gene4045 2.5e-193 681.4 Sphingobacteriia carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0661 Bacteria 1INWJ@117747,4NEQ0@976,COG0458@1,COG0458@2 NA|NA|NA EF Carbamoyl-phosphate synthase MAG.T22.56_02139 1122621.ATZA01000007_gene834 6e-37 161.0 Sphingobacteriia nudL GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 Bacteria 1IT9X@117747,4NM6C@976,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T22.56_02140 1123278.KB893577_gene1326 1.2e-52 212.6 Cytophagia yjdI 1.6.3.4 ko:K22405 ko00000,ko01000 Bacteria 47QRI@768503,4NVG3@976,COG3369@1,COG3369@2,COG3592@1,COG3592@2 NA|NA|NA S Divergent 4Fe-4S mono-cluster MAG.T22.56_02141 1218108.KB908292_gene1546 1.5e-44 186.4 Flavobacteriia Bacteria 1HYXZ@117743,4NH74@976,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) MAG.T22.56_02142 929562.Emtol_2416 1.1e-38 166.4 Cytophagia yhhW ko:K06911 ko00000 Bacteria 47N6P@768503,4NGJ5@976,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family MAG.T22.56_02143 929562.Emtol_2416 1.5e-24 118.2 Cytophagia yhhW ko:K06911 ko00000 Bacteria 47N6P@768503,4NGJ5@976,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family MAG.T22.56_02144 485918.Cpin_1953 6.3e-166 591.3 Sphingobacteriia 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1IP25@117747,4NFK4@976,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T22.56_02145 153721.MYP_2336 1.8e-25 122.9 Cytophagia Bacteria 28PR3@1,2ZCD0@2,47RVI@768503,4NMAF@976 NA|NA|NA MAG.T22.56_02146 925409.KI911562_gene2887 4.1e-84 317.8 Sphingobacteriia pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1IQ1X@117747,4NFCU@976,COG2518@1,COG2518@2 NA|NA|NA O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins MAG.T22.56_02148 1123248.KB893359_gene2066 2.7e-126 458.4 Sphingobacteriia queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1IP9F@117747,4NFCJ@976,COG1600@1,COG1600@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) MAG.T22.56_02149 485918.Cpin_2223 8e-63 246.9 Sphingobacteriia yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1IQV2@117747,4NF0D@976,COG1739@1,COG1739@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0029, Impact, N-terminal MAG.T22.56_02150 1296416.JACB01000004_gene1060 1.2e-15 89.0 Aquimarina Bacteria 1HWX9@117743,2YJ5X@290174,4NGWA@976,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.56_02151 700598.Niako_2665 5.7e-80 304.3 Sphingobacteriia Bacteria 1IR6D@117747,4NDVI@976,COG1235@1,COG1235@2 NA|NA|NA S COGs COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I MAG.T22.56_02153 929556.Solca_0752 2.5e-15 87.4 Sphingobacteriia Bacteria 1IZQ7@117747,2EKY3@1,33EMM@2,4NXXP@976 NA|NA|NA MAG.T22.56_02154 402612.FP1556 3.9e-43 182.2 Flavobacterium Bacteria 1I3RE@117743,2NX7E@237,4NSR1@976,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease MAG.T22.56_02155 402612.FP1531 1.4e-97 364.0 Flavobacteriia Bacteria 1I283@117743,4PMP9@976,COG3593@1,COG3593@2 NA|NA|NA L DNA synthesis involved in DNA repair MAG.T22.56_02156 1313421.JHBV01000016_gene5497 5.3e-34 152.1 Bacteria 3.4.17.22 ko:K07752 ko00000,ko01000,ko01002 Bacteria COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides MAG.T22.56_02157 1123248.KB893318_gene4247 5.2e-12 78.2 Bacteria Bacteria COG2849@1,COG2849@2 NA|NA|NA MAG.T22.56_02158 1267211.KI669560_gene1847 3.2e-40 171.0 Sphingobacteriia nfuA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K07400,ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 1ISU6@117747,4NS6K@976,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T22.56_02160 485918.Cpin_0389 8.8e-64 250.0 Sphingobacteriia frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1IRU0@117747,4NF95@976,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another MAG.T22.56_02161 700598.Niako_0938 2e-89 335.9 Sphingobacteriia Bacteria 1IQSK@117747,4NI60@976,COG3000@1,COG3000@2 NA|NA|NA I PFAM Fatty acid hydroxylase superfamily MAG.T22.56_02162 485918.Cpin_5451 1.2e-46 192.6 Sphingobacteriia MA20_25125 Bacteria 1ISGG@117747,4NNQG@976,COG2947@1,COG2947@2 NA|NA|NA S EVE domain MAG.T22.56_02163 153721.MYP_3392 2.7e-41 175.6 Cytophagia rebM Bacteria 47K6K@768503,4NE6P@976,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T22.56_02164 1007103.AFHW01000001_gene4866 2.7e-30 138.7 Paenibacillaceae Bacteria 1VJ1T@1239,274WH@186822,4HQ2E@91061,COG3797@1,COG3797@2 NA|NA|NA S Protein of unknown function (DUF1697) MAG.T22.56_02165 1123278.KB893571_gene2214 1.9e-63 248.8 Cytophagia ko:K04767,ko:K07168 ko00000 Bacteria 47P6M@768503,4NMHI@976,COG3448@1,COG3448@2 NA|NA|NA T HPP family MAG.T22.56_02166 700598.Niako_5482 4.4e-97 362.1 Sphingobacteriia Bacteria 1IP1E@117747,4NG8A@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat-containing protein MAG.T22.56_02167 485918.Cpin_1604 1.1e-118 433.3 Sphingobacteriia ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iAF987.Gmet_2853,iYO844.BSU38550 Bacteria 1IP2X@117747,4NEJY@976,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase MAG.T22.56_02168 1121007.AUML01000031_gene2691 8.5e-10 71.2 Aquimarina Bacteria 1IAG9@117743,2EFGC@1,2YH27@290174,33991@2,4NW4T@976 NA|NA|NA MAG.T22.56_02169 1120966.AUBU01000008_gene2565 4.6e-50 205.3 Cytophagia 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 47PTG@768503,4NFEN@976,COG0793@1,COG0793@2 NA|NA|NA M PFAM Peptidase family S41 MAG.T22.56_02170 700598.Niako_2069 2e-229 802.0 Sphingobacteriia msbA2 ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1IQ3V@117747,4PKCT@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T22.56_02172 700598.Niako_4943 9.5e-14 81.6 Sphingobacteriia tuf GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 iSB619.SA_RS02960 Bacteria 1IPDP@117747,4NEWS@976,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis MAG.T22.56_02173 929713.NIASO_15320 4.7e-90 338.2 Sphingobacteriia Bacteria 1INY2@117747,4NJEQ@976,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V MAG.T22.56_02175 1123008.KB905694_gene1890 5.7e-10 69.7 Porphyromonadaceae secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 22YRZ@171551,2FUTR@200643,4NUSJ@976,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation MAG.T22.56_02176 485918.Cpin_1702 2.6e-71 275.0 Sphingobacteriia nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1INR8@117747,4NF2X@976,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination MAG.T22.56_02178 1150600.ADIARSV_3064 3.2e-13 84.3 Sphingobacteriia Bacteria 1ISZ3@117747,28JMZ@1,2Z9EE@2,4NKS8@976 NA|NA|NA MAG.T22.56_02179 1123248.KB893323_gene1608 1.6e-107 397.1 Bacteroidetes Bacteria 4PKV1@976,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase MAG.T22.56_02180 1123248.KB893326_gene1400 1.7e-78 299.3 Sphingobacteriia mlaE ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1IQDU@117747,4NEZ8@976,COG0767@1,COG0767@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents permease component MAG.T22.56_02181 1123248.KB893317_gene4278 7.1e-290 1003.4 Sphingobacteriia secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1IP7W@117747,4NE1X@976,COG0341@1,COG0341@2,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T22.56_02182 485918.Cpin_1872 3.1e-111 408.7 Sphingobacteriia ko:K09928 ko00000 Bacteria 1IS4P@117747,4NETR@976,COG1216@1,COG1216@2,COG3216@1,COG3216@2 NA|NA|NA M Uncharacterized protein conserved in bacteria (DUF2062) MAG.T22.56_02183 509635.N824_03760 1.5e-51 209.5 Bacteroidetes Bacteria 4NIEZ@976,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T22.56_02184 761193.Runsl_4819 1.1e-35 156.4 Cytophagia cspA ko:K03704 ko00000,ko03000 Bacteria 47QKE@768503,4NNNH@976,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain MAG.T22.56_02186 700598.Niako_5590 3.6e-152 545.0 Sphingobacteriia dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1IPIQ@117747,4NF8P@976,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T22.56_02187 700598.Niako_3678 1e-15 90.9 Bacteria ispH 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 Bacteria COG0382@1,COG0382@2 NA|NA|NA H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate MAG.T22.56_02188 468059.AUHA01000002_gene1347 1.7e-237 828.6 Sphingobacteriia pccB 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ23@117747,4NEMJ@976,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) MAG.T22.56_02189 1227739.Hsw_2367 1.6e-29 136.0 Cytophagia trxC Bacteria 47RGU@768503,4NQ9U@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T22.56_02190 755732.Fluta_3302 1.3e-62 248.1 Cryomorphaceae Bacteria 1HXYW@117743,2PB35@246874,4NG4J@976,COG1289@1,COG1289@2 NA|NA|NA S PFAM Fusaric acid resistance protein family MAG.T22.56_02191 925409.KI911562_gene1808 1.3e-65 256.9 Sphingobacteriia lolE_1 ko:K09808 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125 Bacteria 1IPU4@117747,4NFWZ@976,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component MAG.T22.56_02192 153721.MYP_1071 2.6e-36 159.5 Bacteroidetes Bacteria 4NQ1R@976,COG2348@1,COG2348@2 NA|NA|NA V Acetyltransferase (GNAT) domain MAG.T22.56_02193 1123248.KB893385_gene4801 1e-57 229.9 Sphingobacteriia grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 1ISPN@117747,4NQ6M@976,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MAG.T22.56_02194 1267211.KI669560_gene1356 8.9e-151 540.0 Sphingobacteriia dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 ko:K03686 ko00000,ko03029,ko03110 Bacteria 1IQ7V@117747,4NF41@976,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T22.56_02195 1454007.JAUG01000145_gene1365 6.9e-97 360.5 Sphingobacteriia 3.1.4.55 ko:K06136,ko:K06167 ko00440,map00440 R10205 RC00296 ko00000,ko00001,ko01000 Bacteria 1IWBX@117747,4NGB4@976,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T22.56_02196 1267211.KI669560_gene414 3.5e-71 274.2 Sphingobacteriia acsA GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 iE2348C_1286.E2348C_4392,iYL1228.KPN_04478 Bacteria 1IPSM@117747,4NEAD@976,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA MAG.T22.56_02197 1121896.JMLU01000004_gene2612 1.5e-20 107.1 Flavobacterium ko:K12057 ko00000,ko02044 3.A.7.11.1 Bacteria 1I7HY@117743,2P0PI@237,4NK8C@976,COG0526@1,COG0526@2 NA|NA|NA CO COG0526, thiol-disulfide isomerase and thioredoxins MAG.T22.56_02199 760192.Halhy_0279 2.7e-91 342.0 Sphingobacteriia Bacteria 1IRJS@117747,4NG0C@976,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T22.56_02200 485918.Cpin_6297 1.9e-45 189.1 Sphingobacteriia yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1ISWG@117747,4NMQT@976,COG1399@1,COG1399@2 NA|NA|NA S acr, cog1399 MAG.T22.56_02201 485918.Cpin_6298 4.5e-21 106.7 Sphingobacteriia rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1IU0H@117747,4NUXU@976,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family MAG.T22.56_02202 485918.Cpin_6299 1.3e-104 386.3 Sphingobacteriia plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1IPMW@117747,4NHEX@976,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA MAG.T22.56_02203 700598.Niako_2052 4.2e-27 127.9 Sphingobacteriia yfbK ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1IP2T@117747,4NFX3@976,COG2304@1,COG2304@2 NA|NA|NA P von Willebrand factor, type A MAG.T22.56_02204 485918.Cpin_1119 4.8e-57 227.6 Sphingobacteriia marC ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1IRXN@117747,4NG94@976,COG2095@1,COG2095@2 NA|NA|NA U PFAM MarC family integral membrane protein MAG.T22.56_02205 700598.Niako_4577 3.4e-164 584.7 Sphingobacteriia pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1INZR@117747,4NE7N@976,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides MAG.T22.56_02206 1121373.KB903643_gene3479 2.2e-21 109.0 Cytophagia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 47R1B@768503,4NP5H@976,COG2885@1,COG2885@2 NA|NA|NA M Protein of unknown function (DUF1573) MAG.T22.56_02207 929556.Solca_0551 1.7e-98 365.9 Sphingobacteriia ubiA 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1IP3B@117747,4NEE3@976,COG0382@1,COG0382@2 NA|NA|NA H 4-hydroxybenzoate polyprenyltransferase MAG.T22.56_02208 1123248.KB893337_gene2343 3e-80 305.1 Sphingobacteriia dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1520 Bacteria 1IP8Q@117747,4NDX2@976,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate MAG.T22.56_02209 1168034.FH5T_08300 5.7e-15 87.4 Bacteria Bacteria COG1716@1,COG1716@2 NA|NA|NA T histone H2A K63-linked ubiquitination MAG.T22.56_02210 1123058.KB894223_gene859 7.9e-62 243.0 Flavobacteriia ptpA 3.4.14.12,3.4.14.5 ko:K01278,ko:K06889,ko:K18574 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 1HXW2@117743,4NF7I@976,COG1506@1,COG1506@2 NA|NA|NA E peptidase MAG.T22.56_02211 929703.KE386491_gene687 6.5e-42 177.6 Cytophagia wzc GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 ko:K16692 ko00000,ko01000,ko01001 Bacteria 47JQC@768503,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM TIGRFAM capsular exopolysaccharide family MAG.T22.56_02212 385682.AFSL01000049_gene505 2.8e-87 329.7 Marinilabiliaceae pglK GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008643,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015772,GO:0015920,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0034645,GO:0036211,GO:0042623,GO:0042626,GO:0043170,GO:0043412,GO:0043413,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0051179,GO:0051234,GO:0055085,GO:0070085,GO:0071702,GO:0071704,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2FMUK@200643,3XJSM@558415,4NE2D@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.56_02213 192952.MM_1141 1.3e-27 130.6 Methanomicrobia Archaea 2N9V5@224756,2XVM0@28890,COG0463@1,arCOG01381@2157 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.56_02214 1237149.C900_02871 1.3e-67 263.8 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_02216 1122605.KB893635_gene3502 3.2e-34 151.0 Sphingobacteriia Bacteria 1IT89@117747,4NS6J@976,COG2315@1,COG2315@2 NA|NA|NA S YjbR MAG.T22.56_02217 290317.Cpha266_2335 3.8e-45 189.5 Bacteria Bacteria COG2931@1,COG2931@2,COG3209@1,COG3209@2,COG3468@1,COG3468@2 NA|NA|NA MU cell adhesion MAG.T22.56_02219 865938.Weevi_2084 6e-156 557.4 Flavobacteriia ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1HXM8@117743,4NE0H@976,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase MAG.T22.56_02220 1492737.FEM08_35000 1.6e-11 74.7 Flavobacteriia Bacteria 1IAXW@117743,2AF0Z@1,314Z9@2,4P7CF@976 NA|NA|NA MAG.T22.56_02221 102129.Lepto7375DRAFT_0160 3.5e-10 71.2 Bacteria Bacteria 2EPF5@1,33H1T@2 NA|NA|NA MAG.T22.56_02222 485918.Cpin_6587 3.2e-59 235.7 Sphingobacteriia Bacteria 1INSV@117747,4NHG3@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.56_02223 700598.Niako_7015 5.9e-07 60.5 Sphingobacteriia Bacteria 1IU01@117747,2EC7G@1,33661@2,4NWXP@976 NA|NA|NA S Domain of unknown function (DUF4288) MAG.T22.56_02224 1122605.KB893644_gene1349 2.1e-33 149.4 Sphingobacteriia Bacteria 1ITT6@117747,4NQRE@976,COG4758@1,COG4758@2 NA|NA|NA S membrane protein (DUF2154) MAG.T22.56_02225 1122176.KB903619_gene5438 1.5e-93 349.7 Sphingobacteriia ribF 2.7.1.26,2.7.7.2 ko:K07011,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1IP9Q@117747,4NFP0@976,COG0196@1,COG0196@2,COG1216@1,COG1216@2 NA|NA|NA H glycosyl transferase family 2 MAG.T22.56_02227 485918.Cpin_2245 1.2e-107 396.7 Sphingobacteriia vicK 2.1.1.80,2.7.13.3,3.1.1.61 ko:K07709,ko:K13924 ko02020,ko02030,map02020,map02030 M00499,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1J0MH@117747,4NEMP@976,COG4191@1,COG4191@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_02230 925409.KI911562_gene2792 2.8e-126 458.4 Sphingobacteriia aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iIT341.HP0663 Bacteria 1IQ18@117747,4NDXJ@976,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system MAG.T22.56_02232 743722.Sph21_2535 1.6e-45 189.9 Sphingobacteriia amiA 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1IQTV@117747,4NGKC@976,COG0860@1,COG0860@2 NA|NA|NA M Ami_3 MAG.T22.56_02237 700598.Niako_4587 1.6e-189 669.1 Sphingobacteriia pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1IPVT@117747,4NHGZ@976,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane MAG.T22.56_02238 468059.AUHA01000003_gene1894 3.6e-33 147.5 Sphingobacteriia pntAA 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1ITS9@117747,4NT78@976,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch MAG.T22.56_02239 700598.Niako_4589 5.1e-135 487.6 Sphingobacteriia pntA GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1IPTC@117747,4NGH1@976,COG3288@1,COG3288@2 NA|NA|NA C PFAM Alanine dehydrogenase PNT MAG.T22.56_02240 700598.Niako_0299 5.8e-122 444.1 Sphingobacteriia ko:K02843 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 1INZA@117747,4NEPH@976,COG0859@1,COG0859@2 NA|NA|NA M Glycosyl transferase, family 9 MAG.T22.56_02241 485918.Cpin_6487 1e-22 114.4 Sphingobacteriia ydjM ko:K03642 ko00000 Bacteria 1ISAE@117747,4PFVG@976,COG0797@1,COG0797@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM Peptidoglycan-binding lysin domain MAG.T22.56_02242 929703.KE386491_gene485 6.2e-84 317.8 Cytophagia rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 47KID@768503,4NEV7@976,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J RNA-binding PUA-like domain of methyltransferase RsmF MAG.T22.56_02244 485918.Cpin_6607 1.6e-18 99.4 Sphingobacteriia nlpD_1 Bacteria 1IT7G@117747,4NFZN@976,COG0739@1,COG0739@2 NA|NA|NA M peptidase M23 MAG.T22.56_02247 485918.Cpin_6604 1.6e-48 199.5 Sphingobacteriia sprT ko:K02742 ko00000 Bacteria 1IS5M@117747,4NDXX@976,COG3091@1,COG3091@2 NA|NA|NA S PFAM SprT-like family MAG.T22.56_02248 700598.Niako_0416 9.7e-99 366.7 Sphingobacteriia xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1IP1B@117747,4NE0E@976,COG4974@1,COG4974@2 NA|NA|NA L Tyrosine recombinase XerC MAG.T22.56_02249 742766.HMPREF9455_00543 2.9e-120 438.7 Porphyromonadaceae nhaS4 Bacteria 22VV7@171551,2FN0I@200643,4NF11@976,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family MAG.T22.56_02250 1185876.BN8_05731 1.4e-98 365.9 Cytophagia 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 47M5U@768503,4NID9@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.56_02251 504472.Slin_6291 5.2e-158 563.9 Cytophagia 5.1.3.10,5.1.3.2 ko:K01784,ko:K12454 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984,R04266 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 Bacteria 47NBZ@768503,4NDX8@976,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase MAG.T22.56_02252 1121373.KB903620_gene2204 3.3e-37 162.9 Cytophagia Bacteria 47V26@768503,4P3SP@976,COG1269@1,COG1269@2 NA|NA|NA C ATP hydrolysis coupled proton transport MAG.T22.56_02253 1358423.N180_01915 3.6e-76 291.2 Sphingobacteriia phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 1ITDP@117747,4NEFZ@976,COG2824@1,COG2824@2 NA|NA|NA P PhnA protein MAG.T22.56_02255 1111730.ATTM01000002_gene1265 2e-62 245.7 Flavobacterium Bacteria 1HX5Z@117743,2NTHQ@237,4NFXD@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.56_02256 925409.KI911562_gene437 8.8e-34 150.6 Sphingobacteriia ko:K03973 ko00000,ko02048,ko03000 Bacteria 1IPE9@117747,4NG3T@976,COG1983@1,COG1983@2 NA|NA|NA KT PFAM PspC domain MAG.T22.56_02257 929713.NIASO_15240 1e-35 156.0 Sphingobacteriia padR ko:K10947 ko00000,ko03000 Bacteria 1IT3H@117747,4NSI4@976,COG1695@1,COG1695@2 NA|NA|NA K transcriptional regulator MAG.T22.56_02258 314345.SPV1_07426 1.7e-84 320.1 Proteobacteria Bacteria 1N7XE@1224,2DBWF@1,2ZBGE@2 NA|NA|NA S Arylsulfotransferase (ASST) MAG.T22.56_02259 1120965.AUBV01000009_gene3113 1.9e-35 156.4 Cytophagia ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 47NFE@768503,4NF36@976,COG1682@1,COG1682@2 NA|NA|NA GM PFAM ABC-2 type transporter MAG.T22.56_02260 485918.Cpin_3081 3e-41 175.3 Sphingobacteriia Bacteria 1ISFV@117747,2CI1G@1,2Z7JA@2,4NF1T@976 NA|NA|NA S Domain of unknown function (DUF4294) MAG.T22.56_02261 880070.Cycma_3135 1.8e-77 295.8 Cytophagia bshB1 ko:K01463 ko00000,ko01000 Bacteria 47K51@768503,4NEDJ@976,COG2120@1,COG2120@2 NA|NA|NA S PFAM GlcNAc-PI de-N-acetylase MAG.T22.56_02262 929713.NIASO_08935 6.1e-27 126.3 Sphingobacteriia rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IUBT@117747,4NS7Q@976,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family MAG.T22.56_02263 1453500.AT05_05450 9.2e-23 112.1 Flavobacteriia rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1I55D@117743,4NURM@976,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family MAG.T22.56_02264 1123248.KB893323_gene1572 2.8e-13 80.5 Sphingobacteriia Bacteria 1IUGW@117747,2ACFD@1,31210@2,4PGVP@976 NA|NA|NA S Domain of unknown function (DUF4295) MAG.T22.56_02265 1341155.FSS13T_18820 1.1e-25 122.5 Flavobacterium Bacteria 1I581@117743,2E3VP@1,2NX4S@237,32YSV@2,4NV28@976 NA|NA|NA MAG.T22.56_02266 880070.Cycma_2022 2.3e-107 396.0 Cytophagia creD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06143 ko00000 Bacteria 47NWS@768503,4NGKY@976,COG4452@1,COG4452@2 NA|NA|NA V Inner membrane protein CreD MAG.T22.56_02267 1123248.KB893359_gene2172 2.7e-32 144.4 Sphingobacteriia MA20_05735 Bacteria 1J0KN@117747,4PKFS@976,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain MAG.T22.56_02268 1270196.JCKI01000009_gene3211 1.1e-46 193.4 Sphingobacteriia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IXH3@117747,4NN8S@976,COG3127@1,COG3127@2 NA|NA|NA Q membrane MAG.T22.56_02269 1123248.KB893355_gene4714 1.8e-229 802.0 Sphingobacteriia nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPN6@117747,4NEXG@976,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source MAG.T22.56_02270 1358423.N180_08125 4.7e-21 108.6 Sphingobacteriia Bacteria 1ITX6@117747,2CJVV@1,336VZ@2,4NW8G@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.56_02271 485918.Cpin_0219 2.8e-58 232.6 Sphingobacteriia gldB Bacteria 1IPUT@117747,4NFZP@976,COG5504@1,COG5504@2 NA|NA|NA O Gliding motility protein, GldB MAG.T22.56_02272 1123248.KB893325_gene1140 3.4e-45 189.1 Sphingobacteriia ydiY ko:K07283 ko00000 Bacteria 1IPAT@117747,4NGB2@976,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function (DUF3078) MAG.T22.56_02273 485918.Cpin_0384 3.1e-25 120.6 Sphingobacteriia scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1IPTD@117747,4NJQE@976,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves MAG.T22.56_02274 700598.Niako_4408 2.9e-43 181.8 Sphingobacteriia 2.3.2.5 ko:K00683 ko00000,ko01000 Bacteria 1IPTM@117747,4NF2M@976,COG3823@1,COG3823@2 NA|NA|NA O Glutamine cyclotransferase MAG.T22.56_02277 700598.Niako_4078 5.9e-36 156.8 Sphingobacteriia Bacteria 1IT08@117747,4NQK3@976,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family protein MAG.T22.56_02278 1150600.ADIARSV_0117 1.9e-123 448.7 Sphingobacteriia arsM 2.1.1.137,2.1.1.79 ko:K00574,ko:K07755 ko00000,ko01000 Bacteria 1IP66@117747,4NEUC@976,COG0500@1,COG2226@2 NA|NA|NA Q Methylase involved in ubiquinone menaquinone biosynthesis MAG.T22.56_02279 743722.Sph21_0231 3.1e-150 538.1 Sphingobacteriia arsB 1.20.4.1 ko:K03325,ko:K03741 ko00000,ko01000,ko02000 2.A.59 Bacteria 1IP3I@117747,4NFG7@976,COG0798@1,COG0798@2 NA|NA|NA P arsenical-resistance protein MAG.T22.56_02280 925409.KI911562_gene440 3.4e-49 201.1 Bacteria arsC 1.20.4.1,2.8.4.2,3.1.3.48 ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701 ko00000,ko01000,ko02000,ko03000 2.A.59 Bacteria COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MAG.T22.56_02281 485918.Cpin_2030 1.2e-102 379.8 Sphingobacteriia noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1IPCV@117747,4NFZ9@976,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family MAG.T22.56_02282 700598.Niako_0940 1.5e-56 225.7 Sphingobacteriia XK27_05000 ko:K06940 ko00000 Bacteria 1ITJ5@117747,4NJH9@976,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T22.56_02284 491205.JARQ01000002_gene197 1.1e-129 470.3 Chryseobacterium nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1HXCP@117743,3ZP88@59732,4NG2F@976,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T22.56_02285 1123248.KB893348_gene294 2.7e-138 498.8 Sphingobacteriia gsiA ko:K02031,ko:K02032,ko:K12371,ko:K13892 ko02010,ko02024,map02010,map02024 M00239,M00324,M00348 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 Bacteria 1IQEC@117747,4NGDP@976,COG1123@1,COG4172@2 NA|NA|NA P Belongs to the ABC transporter superfamily MAG.T22.56_02286 743722.Sph21_3309 3.3e-16 91.7 Sphingobacteriia Bacteria 1IUGZ@117747,2DHK0@1,3003D@2,4PGVR@976 NA|NA|NA MAG.T22.56_02287 1268240.ATFI01000008_gene2364 3.7e-21 107.5 Bacteroidaceae ko:K06975 ko00000 Bacteria 2FT5E@200643,4ARDW@815,4NST0@976,COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase MAG.T22.56_02288 485917.Phep_2793 1.5e-48 198.7 Sphingobacteriia Bacteria 1IYYX@117747,4NS6V@976,COG0662@1,COG0662@2 NA|NA|NA G Cupin 2, conserved barrel MAG.T22.56_02289 755732.Fluta_0632 6.8e-14 84.0 Flavobacteriia Bacteria 1IA3P@117743,2EEME@1,338FB@2,4NW20@976 NA|NA|NA MAG.T22.56_02290 700598.Niako_7354 1.1e-248 865.9 Sphingobacteriia uvrA2 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1IQY4@117747,4NEHM@976,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T22.56_02291 153721.MYP_3133 4.8e-93 347.8 Cytophagia ygiD GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 1.13.11.8 ko:K04100,ko:K15777 ko00362,ko00624,ko00627,ko00965,ko01120,map00362,map00624,map00627,map00965,map01120 R01632,R03550,R04280,R08836,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 Bacteria 47KW5@768503,4NFGT@976,COG3384@1,COG3384@2 NA|NA|NA S PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase MAG.T22.56_02296 1406840.Q763_12715 1.4e-69 270.8 Flavobacterium Bacteria 1IKCE@117743,2DBTS@1,2NY7R@237,2ZB0P@2,4NGP7@976 NA|NA|NA S Domain of unknown function (DUF4397) MAG.T22.56_02297 485918.Cpin_6619 1e-273 949.1 Sphingobacteriia rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1INSH@117747,4NDW9@976,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 MAG.T22.56_02298 1122169.AREN01000008_gene728 3.4e-24 118.2 Legionellales Bacteria 1JDXC@118969,1NGQM@1224,1T6NF@1236,COG2340@1,COG2340@2 NA|NA|NA S Cysteine-rich secretory protein family MAG.T22.56_02299 485918.Cpin_6578 3.5e-193 681.0 Sphingobacteriia yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 R10649 RC00003,RC03221 ko00000,ko01000,ko03016 Bacteria 1INWM@117747,4NE0R@976,COG0621@1,COG0621@2 NA|NA|NA J 2-methylthioadenine synthetase MAG.T22.56_02300 313590.MED134_13976 3.9e-11 75.1 Dokdonia Bacteria 1I29M@117743,29VE2@1,30GUS@2,37F1F@326319,4NP29@976 NA|NA|NA MAG.T22.56_02301 1121481.AUAS01000007_gene1051 3.8e-31 142.1 Cytophagia Bacteria 2DE6B@1,2ZKPA@2,47WPC@768503,4P8R5@976 NA|NA|NA MAG.T22.56_02302 1270196.JCKI01000003_gene2252 1e-146 526.6 Sphingobacteriia purM 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ5E@117747,4NE4E@976,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase MAG.T22.56_02303 925409.KI911562_gene782 1.8e-115 422.5 Sphingobacteriia selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K06917 ko00000,ko01000,ko03016 Bacteria 1IRWP@117747,4NH7W@976,COG2603@1,COG2603@2 NA|NA|NA S Rhodanese Homology Domain MAG.T22.56_02304 1267211.KI669560_gene693 4.9e-132 477.6 Sphingobacteriia selD GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574 Bacteria 1INUS@117747,4NI4R@976,COG0709@1,COG0709@2 NA|NA|NA E Synthesizes selenophosphate from selenide and ATP MAG.T22.56_02306 485918.Cpin_1114 1.7e-190 672.5 Sphingobacteriia fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1IQD6@117747,4NEA4@976,COG1022@1,COG1022@2 NA|NA|NA I AMP-dependent synthetase MAG.T22.56_02307 760568.Desku_0904 1.3e-22 113.6 Bacteria Bacteria 2EI39@1,33BUS@2 NA|NA|NA MAG.T22.56_02312 984262.SGRA_1443 1.1e-23 117.1 Sphingobacteriia Bacteria 1IQ7T@117747,4NDUW@976,COG2932@1,COG2932@2 NA|NA|NA K transcriptional regulator MAG.T22.56_02313 700598.Niako_5028 3.3e-142 511.5 Sphingobacteriia Bacteria 1IQH3@117747,4NEBI@976,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.56_02314 984262.SGRA_0903 6.2e-62 243.8 Sphingobacteriia rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1IRUX@117747,4NNKW@976,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose MAG.T22.56_02315 485918.Cpin_6212 7.7e-56 223.4 Sphingobacteriia yajQ GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K09767 ko00000 Bacteria 1IRSS@117747,4NMBZ@976,COG1666@1,COG1666@2 NA|NA|NA S Belongs to the UPF0234 family MAG.T22.56_02316 761193.Runsl_0176 1.2e-17 97.4 Cytophagia Bacteria 47U5D@768503,4P1CD@976,COG2885@1,COG2885@2 NA|NA|NA M OmpA family MAG.T22.56_02317 485918.Cpin_3740 2.4e-84 318.9 Sphingobacteriia yheS ko:K06158 ko00000,ko03012 Bacteria 1IPB4@117747,4NG1W@976,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.56_02318 1123248.KB893325_gene1168 1e-88 333.6 Sphingobacteriia Bacteria 1J0CK@117747,4NMGT@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_02319 485918.Cpin_0165 1.5e-159 569.3 Sphingobacteriia ycaJ ko:K07478 ko00000 Bacteria 1IPEJ@117747,4NEV8@976,COG2256@1,COG2256@2 NA|NA|NA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase MAG.T22.56_02320 1123248.KB893314_gene3385 7.5e-07 60.8 Sphingobacteriia Bacteria 1IUG8@117747,4NV2M@976,COG0526@1,COG0526@2 NA|NA|NA CO AhpC/TSA family MAG.T22.56_02322 984262.SGRA_1972 4.3e-43 182.2 Sphingobacteriia Bacteria 1J0XD@117747,4NF7P@976,COG1196@1,COG1196@2 NA|NA|NA D protein involved in exopolysaccharide biosynthesis MAG.T22.56_02324 760192.Halhy_2631 2.3e-131 475.3 Sphingobacteriia glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 1IPQZ@117747,4NE8Q@976,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source MAG.T22.56_02325 1123057.P872_03275 1.3e-99 369.4 Cytophagia glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 47KVG@768503,4NE8Q@976,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source MAG.T22.56_02326 1121889.AUDM01000011_gene2759 3.2e-194 684.5 Flavobacterium metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1HX18@117743,2NSI7@237,4NG7Y@976,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme MAG.T22.56_02327 1121895.Q765_18080 2.8e-09 68.9 Flavobacterium Bacteria 1IMXD@117743,2NV4Y@237,4NJHV@976,COG3291@1,COG3291@2 NA|NA|NA O Fibronectin type 3 domain MAG.T22.56_02328 1123248.KB893321_gene544 8.3e-273 946.4 Sphingobacteriia Bacteria 1IW7P@117747,4NF4B@976,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T22.56_02329 1270196.JCKI01000003_gene1841 1.5e-56 226.9 Bacteroidetes Bacteria 28ISW@1,2Z8RZ@2,4NJ4I@976 NA|NA|NA MAG.T22.56_02330 1123248.KB893348_gene194 9e-80 304.3 Sphingobacteriia Bacteria 1IWR7@117747,4NJMF@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2 NA|NA|NA T Y_Y_Y domain MAG.T22.56_02331 1123248.KB893348_gene195 1.6e-60 239.6 Sphingobacteriia lytT ko:K02477,ko:K07705,ko:K11641 ko02020,map02020 M00492,M00494 ko00000,ko00001,ko00002,ko02022 Bacteria 1ISF2@117747,4NGBF@976,COG3279@1,COG3279@2 NA|NA|NA T Response regulator receiver domain MAG.T22.56_02332 1123248.KB893348_gene188 3.5e-22 111.3 Sphingobacteriia Bacteria 1IZ69@117747,2E3Q9@1,32YN7@2,4NWH3@976 NA|NA|NA S tRNA_anti-like MAG.T22.56_02333 760192.Halhy_2436 3.8e-43 181.8 Bacteroidetes Bacteria 4NX4D@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_02334 1121957.ATVL01000006_gene2983 2.2e-15 88.6 Cytophagia Bacteria 47SR4@768503,4NVAQ@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.56_02335 926562.Oweho_1263 1.4e-42 179.5 Cryomorphaceae Bacteria 1I2C8@117743,2PBTM@246874,4NSJH@976,COG2353@1,COG2353@2 NA|NA|NA S YceI-like domain MAG.T22.56_02336 1121904.ARBP01000004_gene927 1.1e-211 743.4 Cytophagia Bacteria 47K3W@768503,4PKVH@976,COG1629@1,COG1629@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.56_02337 1218103.CIN01S_10_02900 5.8e-50 204.9 Chryseobacterium oatA Bacteria 1I1JG@117743,3ZQ8I@59732,4NTEA@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.56_02338 485918.Cpin_6508 1e-104 386.3 Sphingobacteriia Bacteria 1IVMW@117747,4PKIQ@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.56_02339 761193.Runsl_0850 9.2e-25 120.2 Cytophagia ko:K02614 ko00360,map00360 R09840 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 47QBG@768503,4NR0Z@976,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T22.56_02340 1267211.KI669560_gene1972 2.1e-24 119.4 Sphingobacteriia Bacteria 1IUMF@117747,4NQAJ@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T22.56_02341 926562.Oweho_3488 7.9e-34 152.5 Bacteria Bacteria COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity MAG.T22.56_02342 929713.NIASO_07640 2.4e-62 246.1 Sphingobacteriia ko:K20541 ko00000,ko02000 4.D.3.1.6 Bacteria 1IQGQ@117747,4NESG@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.56_02343 45351.EDO25669 1.3e-76 292.7 Metazoa Metazoa 3AV5S@33154,3C3FS@33208,COG0217@1,KOG2972@2759 NA|NA|NA K rRNA small subunit methyltransferase G MAG.T22.56_02345 929713.NIASO_04310 5.5e-95 354.0 Sphingobacteriia yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 1IQCX@117747,4NE8Y@976,COG0217@1,COG0217@2 NA|NA|NA K transcriptional regulatory protein MAG.T22.56_02347 700598.Niako_1516 3.3e-222 777.7 Sphingobacteriia pcd GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 1INP0@117747,4NFPJ@976,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T22.56_02349 755732.Fluta_2641 6.3e-130 470.7 Flavobacteriia ko:K09930 ko00000 Bacteria 1I1TI@117743,4NJE1@976,COG3220@1,COG3220@2 NA|NA|NA S Protein of unknown function (DUF692) MAG.T22.56_02351 469617.FUAG_01630 5.3e-45 187.6 Fusobacteria rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 379FK@32066,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose MAG.T22.56_02352 700598.Niako_6219 5.2e-17 95.1 Bacteria ko:K12976,ko:K21572 ko00000,ko01000,ko01005,ko02000 8.A.46.1,8.A.46.3 Bacteria COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.56_02353 1168289.AJKI01000034_gene3542 5e-44 185.3 Bacteroidetes Bacteria 2FJBM@1,34B1H@2,4P63P@976 NA|NA|NA MAG.T22.56_02354 925409.KI911562_gene2140 1.5e-293 1015.0 Sphingobacteriia parE 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1IQV0@117747,4NF18@976,COG0187@1,COG0187@2 NA|NA|NA L Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit MAG.T22.56_02355 1239962.C943_00131 1e-26 125.9 Cytophagia hrpX GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0030260,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044403,GO:0044409,GO:0044419,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 47RUM@768503,4NVDF@976,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator MAG.T22.56_02356 468059.AUHA01000003_gene1685 9.6e-129 466.8 Sphingobacteriia blt ko:K03761 ko00000,ko02000 2.A.1.6.2 Bacteria 1IW8Q@117747,4NG3R@976,COG2271@1,COG2271@2 NA|NA|NA G MFS_1 like family MAG.T22.56_02357 1469557.JSWF01000028_gene2982 9.8e-27 127.5 Flavobacteriia Bacteria 1HXVY@117743,4NHRP@976,COG1360@1,COG1360@2,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.56_02358 925409.KI911562_gene817 5.7e-84 317.4 Sphingobacteriia mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129,3.4.16.4 ko:K03814,ko:K05365 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1IRZ0@117747,4NF90@976,COG0744@1,COG0744@2 NA|NA|NA M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors MAG.T22.56_02359 485918.Cpin_1051 2.7e-92 345.1 Sphingobacteriia uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 iLJ478.TM1398 Bacteria 1IPRJ@117747,4NF2B@976,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T22.56_02360 700598.Niako_7008 1.2e-72 279.6 Sphingobacteriia upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1IR1N@117747,4NFZM@976,COG0035@1,COG0035@2 NA|NA|NA F uracil phosphoribosyltransferase MAG.T22.56_02361 485918.Cpin_1194 1.9e-72 279.6 Sphingobacteriia ko:K06076 ko00000,ko02000 1.B.9 Bacteria 1IYCH@117747,4PN73@976,COG2067@1,COG2067@2 NA|NA|NA I Type IX secretion system membrane protein PorP/SprF MAG.T22.56_02362 1270196.JCKI01000001_gene3670 1.3e-40 172.6 Sphingobacteriia M1-1022 1.8.5.2 ko:K15977,ko:K16937 ko00920,ko01120,map00920,map01120 R07177 ko00000,ko00001,ko01000 3.D.4.9 Bacteria 1ITB2@117747,4NTM8@976,COG2259@1,COG2259@2 NA|NA|NA S DoxX MAG.T22.56_02364 485918.Cpin_1281 2.8e-131 475.3 Sphingobacteriia ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1IQIS@117747,4NE1T@976,COG1078@1,COG1078@2 NA|NA|NA S phosphohydrolase MAG.T22.56_02365 485918.Cpin_6609 5.3e-185 654.4 Sphingobacteriia ponA 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1IQ85@117747,4NECJ@976,COG5009@1,COG5009@2 NA|NA|NA M PFAM Penicillin binding protein transpeptidase domain MAG.T22.56_02366 929703.KE386491_gene1321 3.6e-21 107.5 Cytophagia Bacteria 47KG1@768503,4NI2T@976,COG3292@1,COG3292@2 NA|NA|NA T PFAM Two component regulator propeller MAG.T22.56_02367 762903.Pedsa_2281 1.9e-168 599.7 Sphingobacteriia Bacteria 1INMY@117747,4PKVH@976,COG1629@1,COG1629@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.56_02368 1122621.ATZA01000003_gene1480 8.6e-40 169.5 Sphingobacteriia sdpR ko:K03892 ko00000,ko03000 Bacteria 1ISSX@117747,4NQCU@976,COG0640@1,COG0640@2 NA|NA|NA K PFAM Bacterial regulatory protein, arsR family MAG.T22.56_02369 761193.Runsl_4430 6.1e-61 240.4 Cytophagia Bacteria 47MD3@768503,4NFVK@976,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein MAG.T22.56_02372 1121875.KB907549_gene1887 1e-10 74.7 Flavobacteriia Bacteria 1I22B@117743,28PUA@1,2ZCJB@2,4NMQI@976 NA|NA|NA MAG.T22.56_02373 1313421.JHBV01000049_gene89 4.8e-52 211.1 Sphingobacteriia Bacteria 1J0B6@117747,4NQWV@976,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-monophosphate binding domain MAG.T22.56_02374 1536774.H70357_04820 1.9e-36 159.5 Paenibacillaceae Bacteria 1V1II@1239,26T2P@186822,28PQP@1,2ZCCM@2,4HGJG@91061 NA|NA|NA S Domain of unknown function (DUF4386) MAG.T22.56_02376 700598.Niako_5136 1.2e-46 193.0 Sphingobacteriia truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1IPUQ@117747,4NFDC@976,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T22.56_02377 485918.Cpin_4031 1.2e-182 646.0 Sphingobacteriia rocD GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 ko:K00819,ko:K00821 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 iYO844.BSU40340 Bacteria 1INU3@117747,4NE93@976,COG4992@1,COG4992@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T22.56_02378 1121887.AUDK01000004_gene273 1.9e-85 322.8 Flavobacterium irk ko:K02026,ko:K08715 M00207 ko00000,ko00002,ko02000 1.A.2.2,3.A.1.1 Bacteria 1HYEP@117743,2NU97@237,4NIYE@976,COG0395@1,COG0395@2 NA|NA|NA G Inward rectifier potassium channel MAG.T22.56_02379 1227739.Hsw_3751 9e-50 204.5 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process MAG.T22.56_02380 485918.Cpin_2331 2.9e-153 548.5 Sphingobacteriia bfmBB 2.3.1.168,2.3.1.61 ko:K00658,ko:K09699 ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00036 R02570,R02571,R02662,R03174,R04097,R08549,R10998 RC00004,RC02727,RC02833,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IP3U@117747,4NED0@976,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex MAG.T22.56_02381 929562.Emtol_0401 4.7e-135 488.0 Cytophagia algI Bacteria 47KQS@768503,4NFK5@976,COG1696@1,COG1696@2 NA|NA|NA M membrane protein involved in D-alanine export MAG.T22.56_02382 1227739.Hsw_2244 7.6e-40 171.4 Cytophagia Bacteria 28KC6@1,2Z9Z6@2,47MPF@768503,4NM0M@976 NA|NA|NA MAG.T22.56_02383 743722.Sph21_2758 9.7e-63 246.9 Sphingobacteriia dedA 3.6.1.27 ko:K03975,ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1J08G@117747,4NMBP@976,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T22.56_02384 929556.Solca_1243 3.1e-174 618.2 Sphingobacteriia gltP ko:K03309,ko:K11102 ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 Bacteria 1INWV@117747,4NDUU@976,COG1301@1,COG1301@2 NA|NA|NA C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family MAG.T22.56_02385 313624.NSP_37050 1.4e-58 233.4 Nostocales acdS 3.5.99.7,4.4.1.15 ko:K01505,ko:K05396 ko00270,map00270 R00997,R01874 RC00382,RC00419 ko00000,ko00001,ko01000 Bacteria 1GFIB@1117,1HKB0@1161,COG2515@1,COG2515@2 NA|NA|NA E 1-aminocyclopropane-1-carboxylate deaminase MAG.T22.56_02386 1122605.KB893637_gene3304 2.2e-11 73.9 Sphingobacteriia era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1INM6@117747,4NES2@976,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism MAG.T22.56_02387 485918.Cpin_1279 1.9e-195 688.7 Sphingobacteriia fabZ GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 Bacteria 1IQB1@117747,4NEJ3@976,COG0764@1,COG0764@2,COG0774@1,COG0774@2 NA|NA|NA IM Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis MAG.T22.56_02388 485918.Cpin_1278 1.4e-83 316.2 Sphingobacteriia lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IQ6Z@117747,4NEBA@976,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.56_02389 929556.Solca_4083 1.3e-52 213.0 Sphingobacteriia ccmA 3.6.3.41 ko:K01990,ko:K02193 ko02010,map02010 M00254,M00259 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.107 Bacteria 1IS33@117747,4NN9G@976,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T22.56_02390 1189612.A33Q_1259 4e-29 133.7 Cytophagia hbdA 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 47NRU@768503,4NGU8@976,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MAG.T22.56_02391 485918.Cpin_7104 9.8e-22 109.8 Sphingobacteriia MA20_19755 Bacteria 1ITU7@117747,4NQ87@976,COG5349@1,COG5349@2 NA|NA|NA S Protein of unknown function (DUF983) MAG.T22.56_02392 700598.Niako_2208 2e-43 183.0 Sphingobacteriia Bacteria 1IU2K@117747,28M3Z@1,32ZEY@2,4NUZS@976 NA|NA|NA MAG.T22.56_02393 1218108.KB908297_gene2842 1.8e-46 192.6 Flavobacteriia rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_1875 Bacteria 1I1CS@117743,4NM42@976,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions MAG.T22.56_02394 925409.KI911562_gene2494 1.9e-48 199.9 Sphingobacteriia mutS2 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1IP9N@117747,4NNNV@976,COG1193@1,COG1193@2 NA|NA|NA L Smr domain MAG.T22.56_02402 1121373.KB903665_gene3122 3.9e-61 241.5 Bacteroidetes Bacteria 4NJC5@976,COG3677@1,COG3677@2 NA|NA|NA L ISXO2-like transposase domain MAG.T22.56_02403 1123248.KB893348_gene273 4.3e-86 325.1 Sphingobacteriia Bacteria 1IPRP@117747,4NG9C@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.56_02404 485918.Cpin_1039 3.3e-35 155.6 Sphingobacteriia lip 3.1.1.3,3.1.1.5,3.1.1.85 ko:K01046,ko:K01048,ko:K19560 ko00561,ko00564,ko00780,ko01100,map00561,map00564,map00780,map01100 M00098,M00572 R02250,R02687,R09725 RC00020,RC00037,RC00041,RC00094,RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria 1ITX3@117747,4NPD2@976,COG2267@1,COG2267@2 NA|NA|NA I PFAM alpha beta hydrolase fold MAG.T22.56_02406 700598.Niako_1542 5.7e-154 551.6 Sphingobacteriia Bacteria 1IPAV@117747,4NFPN@976,COG1470@1,COG1470@2 NA|NA|NA S CarboxypepD_reg-like domain MAG.T22.56_02407 1089547.KB913013_gene1353 9.9e-125 453.4 Cytophagia 5.1.3.10,5.1.3.2 ko:K01784,ko:K12454 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984,R04266 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 Bacteria 47KZ8@768503,4NJAU@976,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein MAG.T22.56_02408 755732.Fluta_2429 1.2e-31 144.8 Bacteria Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T22.56_02409 700598.Niako_0238 3.4e-19 103.2 Sphingobacteriia Bacteria 1IZ56@117747,4PJ0G@976,COG4733@1,COG4733@2,COG5492@1,COG5492@2 NA|NA|NA N cellulase activity MAG.T22.56_02410 264203.ZMO1932 3.1e-10 72.8 Sphingomonadales Bacteria 1PMS3@1224,2AAG6@1,2KA7E@204457,2V0C5@28211,30ZT4@2 NA|NA|NA MAG.T22.56_02411 867902.Ornrh_0937 6.1e-13 80.5 Flavobacteriia ropB Bacteria 1I4NY@117743,4NS7C@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.56_02414 1123248.KB893359_gene2052 1.6e-237 829.3 Bacteria Bacteria COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T22.56_02415 1123248.KB893348_gene193 3.3e-44 184.9 Sphingobacteriia Bacteria 1IXPV@117747,4NI82@976,COG2353@1,COG2353@2 NA|NA|NA S YceI-like domain MAG.T22.56_02416 445970.ALIPUT_01903 1.3e-32 146.0 Rikenellaceae ftcD 2.1.2.5,4.3.1.4 ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 Bacteria 22U9H@171550,2FMWT@200643,4NFE3@976,COG3404@1,COG3404@2,COG3643@1,COG3643@2 NA|NA|NA E Formiminotransferase domain, N-terminal subdomain MAG.T22.56_02418 700598.Niako_2176 1.5e-52 212.2 Sphingobacteriia Bacteria 1ISFT@117747,28NYH@1,2ZBVN@2,4NMB2@976 NA|NA|NA S Belongs to the UPF0403 family MAG.T22.56_02419 1122605.KB893626_gene2703 1.4e-56 226.1 Sphingobacteriia gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 1IRC3@117747,4NEDG@976,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP MAG.T22.56_02420 1267211.KI669560_gene214 2.8e-129 468.8 Sphingobacteriia tlyC Bacteria 1IX4W@117747,4NG0I@976,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain MAG.T22.56_02421 714943.Mucpa_4007 2.7e-169 602.1 Sphingobacteriia pafA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1IP8D@117747,4NE94@976,COG1524@1,COG1524@2 NA|NA|NA P type I phosphodiesterase nucleotide pyrophosphatase MAG.T22.56_02422 1267211.KI669560_gene2056 7.1e-170 603.6 Sphingobacteriia kbl 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1IQY7@117747,4NFRY@976,COG0156@1,COG0156@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.56_02423 1358423.N180_11780 4.6e-107 394.0 Sphingobacteriia hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IPBI@117747,4NFI7@976,COG3185@1,COG3185@2 NA|NA|NA E 4-hydroxyphenylpyruvate dioxygenase MAG.T22.56_02424 485918.Cpin_5418 5.7e-66 257.7 Sphingobacteriia yafK Bacteria 1ISMP@117747,4NNK3@976,COG3034@1,COG3034@2 NA|NA|NA S ErfK YbiS YcfS YnhG family protein MAG.T22.56_02425 1267211.KI669560_gene1771 4.8e-59 235.0 Sphingobacteriia Bacteria 1IUAK@117747,2BG4X@1,33858@2,4NW0E@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.56_02426 925409.KI911562_gene2353 2.8e-139 501.5 Sphingobacteriia trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 1IQ1P@117747,4NEVX@976,COG0492@1,COG0492@2 NA|NA|NA C Thioredoxin reductase MAG.T22.56_02427 485918.Cpin_5945 8.5e-50 204.1 Sphingobacteriia 2.7.11.1,6.3.2.4 ko:K01921,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01001,ko01011 Bacteria 1IRHH@117747,4NSUI@976,COG2815@1,COG2815@2 NA|NA|NA S PASTA domain containing protein MAG.T22.56_02428 485918.Cpin_5946 4.7e-122 444.5 Sphingobacteriia ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1INQY@117747,4NE9P@976,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family MAG.T22.56_02429 313606.M23134_06828 4.5e-63 248.1 Cytophagia ko:K02477 ko00000,ko02022 Bacteria 47PTI@768503,4NFPV@976,COG3279@1,COG3279@2 NA|NA|NA T Response regulator of the LytR AlgR family MAG.T22.56_02430 313606.M23134_06827 6.8e-93 348.6 Cytophagia Bacteria 47XEG@768503,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2 NA|NA|NA T Histidine kinase MAG.T22.56_02434 700598.Niako_3059 4.2e-15 88.2 Bacteria btuE GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0005575,GO:0005623,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family MAG.T22.56_02435 1443665.JACA01000001_gene2523 6.4e-37 162.5 Flavobacteriia Bacteria 1HYFY@117743,4NHYT@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA M TIGRFAM YD repeat MAG.T22.56_02437 485918.Cpin_6221 1.7e-22 112.5 Sphingobacteriia ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1IT4S@117747,4NQXY@976,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T22.56_02438 926549.KI421517_gene1336 4.1e-31 141.4 Cytophagia ompH ko:K06142 ko00000 Bacteria 47VW2@768503,4NSCM@976,COG2825@1,COG2825@2 NA|NA|NA M Outer membrane protein (OmpH-like) MAG.T22.56_02439 485918.Cpin_1053 3.8e-53 214.5 Sphingobacteriia ompH ko:K06142 ko00000 Bacteria 1IS3M@117747,4NH46@976,COG2825@1,COG2825@2 NA|NA|NA M outer membrane chaperone Skp (OmpH) MAG.T22.56_02440 925409.KI911562_gene901 1.8e-108 399.4 Sphingobacteriia bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 1IR22@117747,4NE6Z@976,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein assembly complex, YaeT protein MAG.T22.56_02441 999541.bgla_1g32760 2.6e-67 261.9 Burkholderiaceae pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1JZMU@119060,1NZUU@1224,2VIXW@28216,COG0259@1,COG0259@2 NA|NA|NA H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) MAG.T22.56_02442 1270196.JCKI01000001_gene3461 4.1e-41 175.3 Sphingobacteriia ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 1IS00@117747,4NNJT@976,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis/export protein MAG.T22.56_02443 929556.Solca_3270 1.6e-18 98.2 Sphingobacteriia cspB ko:K03704 ko00000,ko03000 Bacteria 1ITTJ@117747,4NURE@976,COG1278@1,COG1278@2 NA|NA|NA K Cold-shock protein MAG.T22.56_02444 1408433.JHXV01000002_gene281 2e-107 396.0 Cryomorphaceae 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 R07063 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 1HX6Z@117743,2PADA@246874,4NERD@976,COG3239@1,COG3239@2 NA|NA|NA I PFAM Fatty acid desaturase MAG.T22.56_02445 485918.Cpin_5445 2.7e-31 143.3 Sphingobacteriia Bacteria 1IRZE@117747,4NFHT@976,COG0457@1,COG0457@2 NA|NA|NA S tetratricopeptide repeat MAG.T22.56_02446 925409.KI911562_gene2407 3.5e-40 171.4 Sphingobacteriia gyrA 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 1IQJH@117747,4NDWQ@976,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T22.56_02447 1121904.ARBP01000044_gene2074 4.1e-18 98.2 Cytophagia Bacteria 2CB8S@1,30PE6@2,47RMQ@768503,4NU1E@976 NA|NA|NA S Protein of unknown function (DUF4199) MAG.T22.56_02448 1123248.KB893317_gene4297 1.9e-47 195.7 Sphingobacteriia 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1IR72@117747,4NQK0@976,COG0262@1,COG0262@2 NA|NA|NA H PFAM RibD C-terminal domain MAG.T22.56_02449 530564.Psta_3105 2.1e-93 349.0 Planctomycetes ypfJ GO:0005575,GO:0005576 ko:K07054 ko00000 Bacteria 2IZ1Y@203682,COG2321@1,COG2321@2 NA|NA|NA S Putative neutral zinc metallopeptidase MAG.T22.56_02450 1408433.JHXV01000004_gene3427 1.4e-30 140.2 Cryomorphaceae Bacteria 1IG0K@117743,2BQVH@1,2PBZG@246874,32JSC@2,4PA9X@976 NA|NA|NA S Putative MetA-pathway of phenol degradation MAG.T22.56_02451 485918.Cpin_2997 2.6e-35 154.8 Sphingobacteriia miaE ko:K06169 ko00000,ko01000,ko03016 Bacteria 1ISGF@117747,4NFY4@976,COG4445@1,COG4445@2 NA|NA|NA FJ COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA MAG.T22.56_02452 1123248.KB893348_gene335 2.5e-84 318.9 Sphingobacteriia miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1IPJH@117747,4NEAE@976,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) MAG.T22.56_02453 485918.Cpin_5956 1.6e-46 193.0 Sphingobacteriia Bacteria 1IRVA@117747,29CCT@1,2ZZB9@2,4NM9K@976 NA|NA|NA S Plasmid pRiA4b ORF-3-like protein MAG.T22.56_02454 485918.Cpin_3755 9.7e-18 95.5 Sphingobacteriia rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IU0V@117747,4NUVR@976,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family MAG.T22.56_02455 1267211.KI669560_gene1964 1.6e-44 185.3 Sphingobacteriia rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ISA4@117747,4NNKU@976,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit MAG.T22.56_02457 925409.KI911562_gene1983 6.9e-50 203.8 Sphingobacteriia ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iYO844.BSU00460 Bacteria 1IPQ2@117747,4NGFC@976,COG1947@1,COG1947@2 NA|NA|NA I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol MAG.T22.56_02458 700598.Niako_2637 7.5e-74 283.9 Sphingobacteriia Bacteria 1IWXG@117747,4NH7K@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T22.56_02459 592029.DDD_0446 8.4e-82 310.8 Flavobacteriia Bacteria 1I1RT@117743,4NFMB@976,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.56_02460 700598.Niako_2639 5.3e-87 327.4 Sphingobacteriia ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1IQ4U@117747,4NEP2@976,COG2884@1,COG2884@2 NA|NA|NA D ABC transporter MAG.T22.56_02462 925409.KI911562_gene2099 1.1e-106 392.9 Sphingobacteriia ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1J1AE@117747,4NMN9@976,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system MAG.T22.56_02464 929713.NIASO_14670 4.2e-188 664.5 Sphingobacteriia yjgR ko:K06915 ko00000 Bacteria 1IPH5@117747,4NF3P@976,COG0433@1,COG0433@2 NA|NA|NA S Bacterial protein of unknown function (DUF853) MAG.T22.56_02465 1123248.KB893314_gene3375 9e-196 689.5 Sphingobacteriia fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1INUJ@117747,4NE9X@976,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome MAG.T22.56_02466 929562.Emtol_0534 1.4e-22 112.8 Cytophagia Bacteria 2AN5I@1,31D3D@2,47QVV@768503,4NQTI@976 NA|NA|NA S Domain of unknown function (DUF4920) MAG.T22.56_02467 700598.Niako_4712 7.5e-119 433.7 Sphingobacteriia hldD 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1IRDN@117747,4NIZG@976,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose MAG.T22.56_02469 1267211.KI669560_gene292 1.6e-34 152.9 Sphingobacteriia ko:K09017 ko00000,ko03000 Bacteria 1ISRH@117747,4NQ99@976,COG1309@1,COG1309@2 NA|NA|NA K PFAM Bacterial regulatory proteins, tetR family MAG.T22.56_02470 485918.Cpin_0386 2.5e-34 151.8 Sphingobacteriia mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1IS4E@117747,4NQ49@976,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell MAG.T22.56_02471 485918.Cpin_0373 7.4e-82 310.5 Sphingobacteriia pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K07094 ko00000,ko01000 Bacteria 1IW5Q@117747,4NER8@976,COG1646@1,COG1646@2 NA|NA|NA I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) MAG.T22.56_02472 1123248.KB893322_gene581 5.4e-235 820.8 Sphingobacteriia pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1IPW0@117747,4NF5B@976,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily MAG.T22.56_02473 1123248.KB893348_gene347 7.2e-158 563.9 Sphingobacteriia sglT_3 Bacteria 1IQ8J@117747,4NEF3@976,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.56_02474 485918.Cpin_6912 1e-24 120.6 Bacteria Bacteria 2EB10@1,3351W@2 NA|NA|NA MAG.T22.56_02475 938709.AUSH02000068_gene2024 1.1e-39 169.1 Bacteroidetes glcD 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 4NEK3@976,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain MAG.T22.56_02476 1122179.KB890436_gene1290 1.2e-23 117.1 Bacteroidetes sagE ko:K07052 ko00000 Bacteria 4NPCK@976,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease family MAG.T22.56_02477 1449063.JMLS01000001_gene4518 7e-19 100.9 Paenibacillaceae cwlM GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1VA3V@1239,26R83@186822,4IQDT@91061,COG0860@1,COG0860@2 NA|NA|NA M Ami_3 MAG.T22.56_02478 1501230.ET33_23500 1.3e-12 80.1 Paenibacillaceae cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1TQ74@1239,26RMV@186822,4HAV3@91061,COG0860@1,COG0860@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase MAG.T22.56_02479 485918.Cpin_7085 3.6e-87 327.8 Sphingobacteriia pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IPXC@117747,4NFB9@976,COG0508@1,COG0508@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T22.56_02480 485918.Cpin_7293 2.7e-185 654.8 Sphingobacteriia glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 iG2583_1286.G2583_3081,iIT341.HP0183 Bacteria 1IPUW@117747,4NE30@976,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism MAG.T22.56_02482 866536.Belba_0068 3.1e-98 364.8 Cytophagia zupT ko:K07238 ko00000,ko02000 2.A.5.5 Bacteria 47NUB@768503,4NGQ8@976,COG0428@1,COG0428@2 NA|NA|NA P PFAM ZIP Zinc transporter MAG.T22.56_02483 485918.Cpin_0591 6.1e-224 783.9 Sphingobacteriia ptpA_1 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 1INWZ@117747,4NHS5@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU peptidase S9 prolyl oligopeptidase active site domain protein MAG.T22.56_02484 700598.Niako_5099 7.8e-50 203.4 Sphingobacteriia Bacteria 1IT2V@117747,4NSE3@976,COG2010@1,COG2010@2 NA|NA|NA C Haem-binding domain MAG.T22.56_02485 929556.Solca_2251 4.4e-63 248.1 Sphingobacteriia Bacteria 1INN1@117747,28HQ3@1,2Z7XW@2,4NF9H@976 NA|NA|NA S Protein of unknown function (DUF2851) MAG.T22.56_02486 925409.KI911562_gene2628 6.8e-42 176.8 Sphingobacteriia osmC ko:K07397 ko00000 Bacteria 1ISTX@117747,4NQ66@976,COG1765@1,COG1765@2 NA|NA|NA O PFAM OsmC-like protein MAG.T22.56_02487 485918.Cpin_1965 2.6e-48 199.1 Sphingobacteriia Bacteria 1IYAK@117747,28MPU@1,2ZAYW@2,4NXA9@976 NA|NA|NA MAG.T22.56_02488 925409.KI911562_gene2786 5.6e-119 434.1 Sphingobacteriia der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 ko:K03977 ko00000,ko03009 Bacteria 1IR18@117747,4NE2J@976,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis MAG.T22.56_02489 700598.Niako_2577 1.5e-188 665.6 Sphingobacteriia rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 1IP0Q@117747,4NEJK@976,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 MAG.T22.56_02490 1123248.KB893320_gene3871 2.1e-62 245.7 Sphingobacteriia dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1IPSK@117747,4NF7T@976,COG0758@1,COG0758@2 NA|NA|NA L DNA protecting protein DprA MAG.T22.56_02491 1408813.AYMG01000001_gene3431 6.6e-74 283.9 Sphingobacteriia ytkL Bacteria 1IRXP@117747,4NGD5@976,COG2220@1,COG2220@2 NA|NA|NA S Belongs to the UPF0173 family MAG.T22.56_02492 1336803.PHEL49_0353 8.5e-26 122.9 Flavobacteriia Bacteria 1I715@117743,4NWDK@976,COG1917@1,COG1917@2 NA|NA|NA S Cupin 2, conserved barrel domain protein MAG.T22.56_02494 313606.M23134_04293 6.5e-48 197.2 Cytophagia ytkL Bacteria 47KU7@768503,4NGD5@976,COG2220@1,COG2220@2 NA|NA|NA S Belongs to the UPF0173 family MAG.T22.56_02495 1519464.HY22_00860 1.1e-30 139.4 Bacteria ko:K06996 ko00000 Bacteria COG3324@1,COG3324@2 NA|NA|NA E translation initiation factor activity MAG.T22.56_02496 760192.Halhy_0882 2.4e-38 166.0 Sphingobacteriia Bacteria 1IWNM@117747,4NHA5@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.56_02497 485918.Cpin_6889 6.1e-65 253.8 Sphingobacteriia yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1IRY6@117747,4NFHQ@976,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase MAG.T22.56_02498 700598.Niako_5476 3.3e-100 371.3 Sphingobacteriia macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IQ8R@117747,4NE5N@976,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T22.56_02499 468059.AUHA01000002_gene732 3.9e-115 421.4 Sphingobacteriia pgtB Bacteria 1IQHK@117747,4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.56_02500 468059.AUHA01000002_gene733 2.1e-117 429.1 Sphingobacteriia Bacteria 1IPPG@117747,4NI5R@976,COG4251@1,COG4251@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.56_02501 468059.AUHA01000002_gene734 1.5e-22 112.5 Bacteria Bacteria COG0784@1,COG0784@2 NA|NA|NA T Response regulator, receiver MAG.T22.56_02502 485918.Cpin_6263 4e-214 750.7 Sphingobacteriia lpdA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IQG6@117747,4NDVC@976,COG1249@1,COG1249@2 NA|NA|NA C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) MAG.T22.56_02503 1034807.FBFL15_0213 1.7e-105 389.0 Flavobacterium ko:K03294 ko00000 2.A.3.2 Bacteria 1I02U@117743,2NSVU@237,4NDU2@976,COG0531@1,COG0531@2 NA|NA|NA E amino acid MAG.T22.56_02505 1120951.AUBG01000002_gene1135 9.3e-31 139.8 Flavobacteriia yuxK Bacteria 1I30U@117743,4NQ93@976,COG3011@1,COG3011@2 NA|NA|NA S Thiol-disulfide oxidoreductase MAG.T22.56_02506 485918.Cpin_7046 1e-47 198.0 Sphingobacteriia Bacteria 1IZE7@117747,2BV6Z@1,32QKE@2,4PCAH@976 NA|NA|NA MAG.T22.56_02507 929556.Solca_4243 3.3e-232 810.8 Sphingobacteriia fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1IPCY@117747,4NEQP@976,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T22.56_02509 1453498.LG45_12380 3.2e-31 141.4 Flavobacteriia maoC 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 Bacteria 1I5PB@117743,4NPYH@976,COG2030@1,COG2030@2 NA|NA|NA I MaoC like domain MAG.T22.56_02510 1123248.KB893318_gene4208 6.1e-132 477.2 Sphingobacteriia tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1INZZ@117747,4NE8E@976,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction MAG.T22.56_02511 929703.KE386491_gene241 4.4e-44 184.9 Cytophagia yfiC GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.223,2.1.1.72 ko:K00571,ko:K15460 ko00000,ko01000,ko02048,ko03016 Bacteria 47QFW@768503,4NG1X@976,COG4123@1,COG4123@2 NA|NA|NA J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) MAG.T22.56_02512 888059.HMPREF9071_1157 1.6e-20 105.9 Capnocytophaga Bacteria 1ERZC@1016,1I54T@117743,2ECUJ@1,336S2@2,4NXEE@976 NA|NA|NA S Psort location CytoplasmicMembrane, score 10.00 MAG.T22.56_02513 755732.Fluta_3487 7.7e-65 253.8 Flavobacteriia Bacteria 1HYJK@117743,4NFQ4@976,COG2102@1,COG2102@2 NA|NA|NA S atp-binding MAG.T22.56_02515 1492737.FEM08_06150 3.2e-42 177.6 Flavobacterium ykkD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K11741,ko:K18925 M00712 ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.5 Bacteria 1I2X4@117743,2NWN9@237,4NQ4U@976,COG2076@1,COG2076@2 NA|NA|NA P Cation transporter MAG.T22.56_02516 1313421.JHBV01000039_gene2797 1.3e-43 182.6 Sphingobacteriia 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1IQPC@117747,4NEKS@976,COG1858@1,COG1858@2 NA|NA|NA C cytochrome c peroxidase MAG.T22.56_02518 925409.KI911562_gene2222 5.5e-26 124.0 Bacteroidetes Bacteria 2EK9Y@1,33E08@2,4NXVI@976 NA|NA|NA MAG.T22.56_02519 485918.Cpin_5102 2e-60 238.8 Sphingobacteriia Bacteria 1IY9X@117747,2C984@1,32U95@2,4NSEJ@976 NA|NA|NA MAG.T22.56_02520 984262.SGRA_4096 8.7e-130 470.3 Sphingobacteriia femD 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQYY@117747,4NFU7@976,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II MAG.T22.56_02521 1122605.KB893637_gene3292 1.1e-16 92.4 Sphingobacteriia ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1IP2E@117747,4NEEN@976,COG1538@1,COG1538@2 NA|NA|NA MU outer membrane efflux protein MAG.T22.56_02522 485918.Cpin_1028 3.1e-91 341.7 Sphingobacteriia suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1IQ46@117747,4NI6D@976,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase MAG.T22.56_02523 485918.Cpin_1027 2.6e-146 525.0 Sphingobacteriia thiL 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU05900 Bacteria 1IQ84@117747,4NDUT@976,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 MAG.T22.56_02526 485918.Cpin_0246 1.3e-86 326.2 Sphingobacteriia tatD ko:K03424 ko00000,ko01000 Bacteria 1INMV@117747,4NEVW@976,COG0084@1,COG0084@2 NA|NA|NA L TIGRFAM hydrolase, TatD family MAG.T22.56_02527 1267211.KI669560_gene1055 2.6e-64 251.9 Sphingobacteriia pgdA_1 Bacteria 1IRUN@117747,4NM7D@976,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase MAG.T22.56_02529 485918.Cpin_6892 6.8e-113 413.7 Sphingobacteriia fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1INTX@117747,4NEVE@976,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH MAG.T22.56_02530 714943.Mucpa_0218 1.9e-84 320.1 Sphingobacteriia Bacteria 1IPCG@117747,4NE6G@976,COG0823@1,COG0823@2,COG2885@1,COG2885@2 NA|NA|NA MU Belongs to the ompA family MAG.T22.56_02531 1121373.KB903633_gene718 1.2e-103 384.0 Cytophagia Bacteria 47SJS@768503,4NJ39@976,COG3291@1,COG3291@2 NA|NA|NA S Domain of unknown function (DUF4465) MAG.T22.56_02532 1267211.KI669560_gene1418 5.3e-53 214.2 Sphingobacteriia trmH 2.1.1.185 ko:K03218 ko00000,ko01000,ko03009 Bacteria 1IRFD@117747,4NF6H@976,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T22.56_02533 1123248.KB893317_gene4263 1.8e-92 345.9 Sphingobacteriia mvaB 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQRT@117747,4NDZH@976,COG0119@1,COG0119@2 NA|NA|NA E Hydroxymethylglutaryl-CoA lyase MAG.T22.56_02534 700598.Niako_3023 1.4e-70 273.1 Sphingobacteriia mqnA 1.21.98.1,4.2.1.151 ko:K07081,ko:K11782,ko:K11784 ko00130,ko01110,map00130,map01110 R08588,R10666 RC02329,RC03232 ko00000,ko00001,ko01000 Bacteria 1ISCN@117747,4NN4W@976,COG1427@1,COG1427@2 NA|NA|NA S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) MAG.T22.56_02535 550540.Fbal_2648 3e-17 94.4 Gammaproteobacteria pspE GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 ko:K03972 ko00000 iE2348C_1286.E2348C_1500,iECABU_c1320.ECABU_c15910,iSDY_1059.SDY_1936,ic_1306.c1779 Bacteria 1RHVM@1224,1SD9C@1236,COG0607@1,COG0607@2 NA|NA|NA P COG0607 Rhodanese-related sulfurtransferase MAG.T22.56_02536 1120965.AUBV01000001_gene3365 3.1e-124 451.4 Cytophagia blh Bacteria 47KD4@768503,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P COGs COG0491 Zn-dependent hydrolase including glyoxylase MAG.T22.56_02543 1123248.KB893326_gene1409 6.8e-120 437.2 Sphingobacteriia tetA ko:K08151,ko:K08153 M00668,M00717 ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8 Bacteria 1INXG@117747,4NFM7@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.56_02547 485918.Cpin_2225 6.8e-52 210.7 Sphingobacteriia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1J0MG@117747,4PN7E@976,COG1629@1,COG4771@2 NA|NA|NA P CarboxypepD_reg-like domain MAG.T22.56_02548 1123248.KB893315_gene3149 6.4e-143 513.8 Sphingobacteriia mrp ko:K03593 ko00000,ko03029,ko03036 Bacteria 1IQKF@117747,4NF5I@976,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP MAG.T22.56_02551 1122216.AUHW01000001_gene715 1.5e-40 172.9 Negativicutes rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,4H2EW@909932,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA MAG.T22.56_02554 1392490.JHZX01000001_gene3064 3.7e-40 171.0 Flavobacteriia cqsS GO:0000155,GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K03413,ko:K10916 ko02020,ko02024,ko02030,ko05111,map02020,map02024,map02030,map05111 M00506,M00513 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1I463@117743,4NUT5@976,COG0784@1,COG0784@2 NA|NA|NA T response regulator, receiver MAG.T22.56_02555 1249975.JQLP01000003_gene71 1.1e-144 520.0 Gillisia Bacteria 1IJ7J@117743,2P77V@244698,4P5EA@976,COG2202@1,COG2202@2,COG3290@1,COG3290@2,COG5000@1,COG5000@2 NA|NA|NA T PAS domain MAG.T22.56_02556 485918.Cpin_0669 1.4e-103 384.0 Sphingobacteriia Bacteria 1IR9Z@117747,4NERG@976,COG0457@1,COG0457@2 NA|NA|NA S Oxygen tolerance MAG.T22.56_02557 929562.Emtol_1564 1.3e-39 169.1 Cytophagia 1.1.1.325 ko:K17745 ko00790,map00790 M00843 R09989,R09990 RC00823,RC02162 ko00000,ko00001,ko00002,ko01000 Bacteria 47M5I@768503,4NG8J@976,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.56_02558 700598.Niako_1169 1.1e-42 179.5 Sphingobacteriia menI GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0034641,GO:0042180,GO:0042181,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 Bacteria 1IT04@117747,4NNYG@976,COG2050@1,COG2050@2 NA|NA|NA Q protein possibly involved in aromatic compounds catabolism MAG.T22.56_02559 485918.Cpin_5447 1.1e-107 397.1 Sphingobacteriia lys2 1.5.1.10,1.5.1.7 ko:K00290,ko:K00293 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R02315 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ3W@117747,4NFM8@976,COG1748@1,COG1748@2 NA|NA|NA E Saccharopine dehydrogenase MAG.T22.56_02561 929713.NIASO_11985 7e-118 430.6 Sphingobacteriia murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1IQA5@117747,4NDWD@976,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein MAG.T22.56_02562 485918.Cpin_6849 1.5e-33 149.1 Sphingobacteriia Bacteria 1IT9G@117747,2CE7N@1,30Q80@2,4NNKP@976 NA|NA|NA MAG.T22.56_02563 485918.Cpin_6848 3.8e-101 374.8 Sphingobacteriia Bacteria 1IPPX@117747,4NFZX@976,COG4990@1,COG4990@2 NA|NA|NA S Domain of unknown function (DUF4872) MAG.T22.56_02564 714943.Mucpa_3855 1.4e-37 162.2 Sphingobacteriia csaA ko:K06878 ko00000 Bacteria 1J0H8@117747,4PMPM@976,COG4430@1,COG4430@2 NA|NA|NA S COG0073 EMAP domain MAG.T22.56_02565 1239962.C943_04256 3.3e-99 368.6 Cytophagia 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 R07063 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 47JP1@768503,4NERD@976,COG3239@1,COG3239@2 NA|NA|NA I fatty acid desaturase MAG.T22.56_02567 1150600.ADIARSV_1047 7e-22 109.4 Sphingobacteriia cspA ko:K03704 ko00000,ko03000 Bacteria 1ITTJ@117747,4NURE@976,COG1278@1,COG1278@2 NA|NA|NA K Cold-shock protein MAG.T22.56_02568 929713.NIASO_13245 4.7e-34 151.8 Sphingobacteriia recQ2 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1IPAP@117747,4NEFD@976,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ MAG.T22.56_02569 1121957.ATVL01000006_gene3301 1.1e-33 151.0 Bacteroidetes Bacteria 2DX8D@1,343UE@2,4P6Q1@976 NA|NA|NA MAG.T22.56_02570 755732.Fluta_3823 3.5e-31 141.4 Flavobacteriia Bacteria 1I3EM@117743,4NQSY@976,COG2197@1,COG2197@2 NA|NA|NA KT LuxR family transcriptional regulator MAG.T22.56_02571 1123057.P872_24690 1.2e-07 63.2 Cytophagia Bacteria 28M1N@1,2ZAGE@2,47JC7@768503,4NIDD@976 NA|NA|NA MAG.T22.56_02572 929713.NIASO_08670 4.8e-35 153.7 Sphingobacteriia Bacteria 1IZ3G@117747,4NVM6@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.56_02573 485918.Cpin_6537 1e-80 306.2 Sphingobacteriia Bacteria 1IPH6@117747,28M4Q@1,2ZAIK@2,4NJC3@976 NA|NA|NA MAG.T22.56_02574 471854.Dfer_3969 7.5e-70 270.4 Cytophagia sdhC ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 2CAZH@1,2Z7RU@2,47NEV@768503,4NGM5@976 NA|NA|NA S TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family MAG.T22.56_02575 485918.Cpin_6915 2.5e-233 815.1 Sphingobacteriia recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1IP0N@117747,4NDZV@976,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) MAG.T22.56_02577 1123248.KB893322_gene589 6e-232 810.1 Sphingobacteriia lysS 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1IQRC@117747,4NDZN@976,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family MAG.T22.56_02578 700598.Niako_1182 1.9e-08 64.3 Sphingobacteriia trmH GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437,ko:K15333 ko00000,ko01000,ko03009,ko03016,ko03036 Bacteria 1IXWW@117747,4NFH3@976,COG0566@1,COG0566@2 NA|NA|NA J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA MAG.T22.56_02579 1150600.ADIARSV_1195 8e-87 327.0 Sphingobacteriia CcmA5 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1IQ6J@117747,4NJ0D@976,COG1131@1,COG1131@2 NA|NA|NA V SMART ATPase, AAA type, core MAG.T22.56_02580 1123248.KB893322_gene614 6.9e-68 263.8 Sphingobacteriia 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1IYAV@117747,4NPSZ@976,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent MAG.T22.56_02581 700598.Niako_5805 2.5e-50 205.3 Sphingobacteriia pqqL ko:K07263 ko00000,ko01000,ko01002 Bacteria 1IPY5@117747,4NEDZ@976,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T22.56_02582 1122132.AQYH01000020_gene18 5.2e-146 524.2 Rhizobiaceae 1.17.1.1 ko:K12452 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000 Bacteria 1MUPN@1224,2TVTA@28211,4BIRJ@82115,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T22.56_02584 1484460.JSWG01000009_gene574 6.8e-25 121.3 Flavobacteriia Bacteria 1I0R6@117743,28MR9@1,2ZAZY@2,4NHMN@976 NA|NA|NA MAG.T22.56_02585 880073.Calab_3218 3.1e-16 91.7 Bacteria 3.6.1.15 ko:K06928 ko00230,ko00730,ko01100,map00230,map00730,map01100 R00086,R00615 RC00002 ko00000,ko00001,ko01000 Bacteria 2AK8E@1,31AYP@2 NA|NA|NA S NTPase MAG.T22.56_02586 1121481.AUAS01000001_gene4388 1.2e-31 143.3 Cytophagia mobA 2.7.7.77,4.6.1.17 ko:K03637,ko:K03752,ko:K13818 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372,R11581 RC03425 ko00000,ko00001,ko01000 Bacteria 47NQP@768503,4NMYW@976,COG0746@1,COG0746@2 NA|NA|NA H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor MAG.T22.56_02587 172045.KS04_19795 2.3e-46 191.4 Elizabethkingia Bacteria 1I2X2@117743,34RHF@308865,4NQ4W@976,COG4898@1,COG4898@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2200) MAG.T22.56_02591 391603.FBALC1_07758 4e-40 172.2 Flavobacteriia ko:K06911 ko00000 Bacteria 1HXX4@117743,4NFZD@976,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family MAG.T22.56_02592 1122605.KB893647_gene439 1.7e-51 209.1 Sphingobacteriia rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1IRYB@117747,4NNW0@976,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 MAG.T22.56_02593 1121898.Q766_06155 3.6e-114 418.3 Flavobacterium 1.6.99.1 ko:K00354,ko:K10680 ko00633,ko01120,map00633,map01120 R00282,R08014,R08017,R08042 RC00001,RC00250 ko00000,ko00001,ko01000 Bacteria 1HYAD@117743,2NU8F@237,4NF98@976,COG1902@1,COG1902@2 NA|NA|NA C NADH flavin oxidoreductase MAG.T22.56_02594 485918.Cpin_7059 1.1e-73 283.1 Sphingobacteriia surE 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1IP3M@117747,4NEJ5@976,COG0496@1,COG0496@2 NA|NA|NA S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates MAG.T22.56_02598 649349.Lbys_2467 4.5e-43 181.0 Cytophagia rfbG 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 47NEA@768503,4NFHJ@976,COG0451@1,COG0451@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T22.56_02599 1250005.PHEL85_3110 6.4e-154 550.8 Polaribacter csdA 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1HY99@117743,3VV06@52959,4NERR@976,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V MAG.T22.56_02600 700598.Niako_0238 3.3e-24 119.4 Sphingobacteriia Bacteria 1IZ56@117747,4PJ0G@976,COG4733@1,COG4733@2,COG5492@1,COG5492@2 NA|NA|NA N cellulase activity MAG.T22.56_02601 761193.Runsl_5147 7.5e-35 154.1 Cytophagia mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 47MUD@768503,4NRHK@976,COG1285@1,COG1285@2 NA|NA|NA S PFAM MgtC SapB transporter MAG.T22.56_02604 1122971.BAME01000046_gene3927 2e-18 97.8 Porphyromonadaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iLJ478.TM0401 Bacteria 22W1X@171551,2FN2K@200643,4NE5R@976,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase MAG.T22.56_02611 1121904.ARBP01000044_gene2067 1.1e-25 124.4 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG0265@1,COG0265@2,COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity MAG.T22.56_02612 1267211.KI669560_gene1575 6.9e-51 206.8 Sphingobacteriia ko:K07090 ko00000 Bacteria 1IRY3@117747,4NFWP@976,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein MAG.T22.56_02613 938709.AUSH02000031_gene1326 6.2e-98 363.6 Bacteroidetes 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 4NEZZ@976,COG0450@1,COG0450@2 NA|NA|NA O PFAM C-terminal domain of 1-Cys peroxiredoxin MAG.T22.56_02614 1280663.ATVR01000014_gene1071 1.5e-14 87.0 Butyrivibrio udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,24850@186801,4BWDS@830,COG0572@1,COG0572@2 NA|NA|NA F Phosphoribulokinase / Uridine kinase family MAG.T22.56_02616 179408.Osc7112_1623 1.5e-28 132.9 Oscillatoriales per1 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1G1KE@1117,1HAFG@1150,COG2367@1,COG2367@2 NA|NA|NA V PFAM beta-lactamase MAG.T22.56_02617 925409.KI911562_gene1163 2.1e-118 432.6 Sphingobacteriia Bacteria 1IPWT@117747,4NFFC@976,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T22.56_02618 1408433.JHXV01000001_gene841 9e-117 427.2 Flavobacteriia 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1IBEY@117743,4NKTY@976,COG1874@1,COG1874@2 NA|NA|NA G Beta-galactosidase MAG.T22.56_02619 700598.Niako_0290 7.6e-146 523.5 Sphingobacteriia pdhB 1.2.4.4,2.2.1.1 ko:K00615,ko:K11381 ko00030,ko00280,ko00640,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00280,map00640,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00036,M00165,M00167 R01067,R01641,R01830,R06590,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00032,RC00226,RC00571,RC00627,RC01560,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1IQ4X@117747,4NE4A@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type MAG.T22.56_02620 269798.CHU_1611 3.7e-61 241.5 Cytophagia mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47JIZ@768503,4NP22@976,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family MAG.T22.56_02621 700598.Niako_6883 6.2e-142 510.4 Sphingobacteriia 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1IR3A@117747,4NEI8@976,COG3958@1,COG3958@2 NA|NA|NA G Transketolase MAG.T22.56_02622 700598.Niako_1173 4.5e-21 107.8 Sphingobacteriia Bacteria 1IZWS@117747,4NVQ5@976,COG5608@1,COG5608@2 NA|NA|NA S Late embryogenesis abundant protein MAG.T22.56_02627 1189620.AJXL01000129_gene1682 1.4e-17 95.5 Flavobacterium 2.4.1.152,2.4.1.65 ko:K20151 ko00000,ko01000,ko01003 GT10 Bacteria 1HXHT@117743,28IN0@1,2NYY0@237,2Z8NG@2,4NNZ4@976 NA|NA|NA S Glycosyltransferase family 10 (fucosyltransferase) C-term MAG.T22.56_02628 1450525.JATV01000003_gene1711 9.6e-155 553.1 Flavobacterium pepC 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1HXT9@117743,2NTRT@237,4NE02@976,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase MAG.T22.56_02629 485918.Cpin_6940 3.7e-24 118.2 Sphingobacteriia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1IXKI@117747,4NICC@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain containing protein MAG.T22.56_02630 1408433.JHXV01000002_gene354 4.7e-40 172.2 Bacteria Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T22.56_02631 1124780.ANNU01000005_gene2415 6.3e-77 293.9 Cytophagia ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 ko:K02195 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko02000 3.A.1.107 iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Bacteria 47MYQ@768503,4NFUS@976,COG0755@1,COG0755@2 NA|NA|NA O PFAM Cytochrome c assembly protein MAG.T22.56_02632 925409.KI911562_gene1838 4.6e-56 224.6 Sphingobacteriia ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193,ko:K02194 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 iECO111_1330.ECO111_2936,iYL1228.KPN_02080 Bacteria 1IP2M@117747,4NFQV@976,COG2386@1,COG2386@2 NA|NA|NA O PFAM Cytochrome c-type biogenesis protein CcmB MAG.T22.56_02633 700598.Niako_5474 2e-66 258.8 Sphingobacteriia trpS 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1INYI@117747,4NETX@976,COG0180@1,COG0180@2 NA|NA|NA J Tryptophanyl-tRNA synthetase MAG.T22.56_02634 485918.Cpin_6885 1.5e-88 332.4 Sphingobacteriia dck Bacteria 1INU0@117747,4NFA8@976,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase MAG.T22.56_02635 485918.Cpin_5920 2.3e-18 98.2 Sphingobacteriia secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1ITYX@117747,4NUYQ@976,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit MAG.T22.56_02636 485918.Cpin_5921 2.5e-93 349.0 Sphingobacteriia mltG ko:K07082 ko00000 Bacteria 1IP2P@117747,4NG17@976,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation MAG.T22.56_02637 485918.Cpin_6520 1.5e-38 165.6 Sphingobacteriia Bacteria 1IT90@117747,4NNVM@976,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor MAG.T22.56_02638 866771.HMPREF9296_1209 2.7e-137 495.0 Bacteroidia Bacteria 2FNC8@200643,4NGHT@976,COG3039@1,COG3039@2 NA|NA|NA L Transposase IS4 family MAG.T22.56_02639 1288963.ADIS_3781 1.3e-08 65.5 Bacteroidetes Bacteria 28M3W@1,2ZAHX@2,4NH0V@976 NA|NA|NA MAG.T22.56_02641 643473.KB235930_gene2788 3.9e-16 92.8 Nostocales Bacteria 1G2XD@1117,1HPC2@1161,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T22.56_02645 1458357.BG58_09875 1.2e-31 143.7 Burkholderiaceae ko:K03543 M00701 ko00000,ko00002,ko02000 8.A.1.1 Bacteria 1K5Z2@119060,1NAMI@1224,2VZSW@28216,COG1566@1,COG1566@2 NA|NA|NA V Biotin-lipoyl like MAG.T22.56_02646 1317124.DW2_14945 1.2e-64 253.1 Thioclava ko:K07011 ko00000 Bacteria 1NE2P@1224,2V85T@28211,2XNTT@285107,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.56_02647 1122605.KB893637_gene3080 7.3e-21 106.7 Sphingobacteriia rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1INQF@117747,4NE2S@976,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit # 2165 queries scanned # Total time (seconds): 12.8154909611 # Rate: 168.94 q/s