# emapper version: emapper-hotfix-numpy-69-gdd722db emapper DB: 2.0
# command: ./emapper.py  -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/emapper//MAG.T21.18/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/Bin_prokka//MAG.T21.18/MAG.T21.18.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/emapper//MAG.T21.18/MAG.T21.18 --usemem --override
# time: Fri Aug 21 05:43:29 2026
#query_name	seed_eggNOG_ortholog	seed_ortholog_evalue	seed_ortholog_score	best_tax_level	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	taxonomic scope	eggNOG OGs	best eggNOG OG	COG Functional cat.	eggNOG free text desc.
MAG.T21.18_00001	1515613.HQ37_00815	3e-74	285.8	Porphyromonadaceae	rnr			ko:K12573,ko:K12585	ko03018,map03018	M00391			ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	22VY8@171551,2FMM6@200643,4NE7T@976,COG0557@1,COG0557@2	NA|NA|NA	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAG.T21.18_00002	1408433.JHXV01000015_gene1712	1.3e-99	369.4	Cryomorphaceae				ko:K07705	ko02020,map02020	M00492			ko00000,ko00001,ko00002,ko02022				Bacteria	1I0BK@117743,2PAUQ@246874,4NKXC@976,COG3279@1,COG3279@2	NA|NA|NA	K	Response regulator of the LytR AlgR family
MAG.T21.18_00003	351160.LRC135	8.7e-65	255.8	Methanomicrobia													Archaea	2NBMQ@224756,2Y2CM@28890,COG3920@1,arCOG02335@2157,arCOG02348@1,arCOG02348@2157	NA|NA|NA	T	HWE histidine kinase
MAG.T21.18_00004	926562.Oweho_2308	1.8e-26	127.5	Cryomorphaceae				ko:K07126					ko00000				Bacteria	1I51X@117743,2PBM8@246874,4NMDX@976,COG2849@1,COG2849@2	NA|NA|NA	S	MORN repeat variant
MAG.T21.18_00005	867902.Ornrh_0947	3e-43	181.4	Flavobacteriia	rpiB		5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000				Bacteria	1I24B@117743,4NNSU@976,COG0698@1,COG0698@2	NA|NA|NA	G	Ribose 5-phosphate isomerase
MAG.T21.18_00006	1356852.N008_06480	9.7e-102	377.5	Cytophagia													Bacteria	47M5P@768503,4NFDJ@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.18_00007	1313421.JHBV01000030_gene2200	2.2e-85	322.8	Sphingobacteriia			1.11.1.15	ko:K03564					ko00000,ko01000				Bacteria	1INVF@117747,4NEEA@976,COG1225@1,COG1225@2	NA|NA|NA	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.18_00009	1313301.AUGC01000012_gene1357	1.5e-60	240.0	Bacteroidetes													Bacteria	4NGVF@976,COG2227@1,COG2227@2	NA|NA|NA	H	Methyltransferase
MAG.T21.18_00010	1094466.KQS_00060	3.8e-236	824.3	Flavobacterium	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363		ko:K03495			R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036				Bacteria	1HWN4@117743,2NTS5@237,4NFNH@976,COG0445@1,COG0445@2	NA|NA|NA	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAG.T21.18_00012	393921.HQ45_07785	1.6e-22	112.5	Bacteroidia	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029				Bacteria	2FS5C@200643,4NS93@976,COG0319@1,COG0319@2	NA|NA|NA	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAG.T21.18_00013	1124780.ANNU01000015_gene1983	1.4e-32	146.0	Cytophagia	rsbW		2.7.11.1	ko:K04757,ko:K08282					ko00000,ko01000,ko01001,ko03021				Bacteria	47QUX@768503,4NRAA@976,COG2172@1,COG2172@2	NA|NA|NA	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_00014	929556.Solca_3842	7.8e-139	501.9	Sphingobacteriia													Bacteria	1J0XD@117747,4NF7P@976,COG1196@1,COG1196@2	NA|NA|NA	D	protein involved in exopolysaccharide biosynthesis
MAG.T21.18_00015	1122176.KB903531_gene2984	6.5e-20	105.9	Bacteria													Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_00017	485917.Phep_3439	2.9e-11	74.7	Sphingobacteriia				ko:K06975					ko00000				Bacteria	1ITR0@117747,4NST0@976,COG2388@1,COG2388@2	NA|NA|NA	S	GCN5-related N-acetyl-transferase
MAG.T21.18_00018	1124780.ANNU01000017_gene1877	5.4e-161	574.3	Cytophagia	gltX		6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016				Bacteria	47K3J@768503,4NEED@976,COG0008@1,COG0008@2	NA|NA|NA	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAG.T21.18_00019	755732.Fluta_1540	1.1e-19	102.8	Cryomorphaceae	folB		1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000				Bacteria	1I2V4@117743,2PB44@246874,4NQ53@976,COG1539@1,COG1539@2	NA|NA|NA	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAG.T21.18_00021	1168034.FH5T_08385	2.4e-134	486.5	Bacteroidia													Bacteria	2FQ6Y@200643,4NDWE@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller
MAG.T21.18_00022	1004149.AFOE01000036_gene834	9.2e-26	124.0	Flavobacteriia	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03584	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1I1E3@117743,4NIBQ@976,COG1381@1,COG1381@2	NA|NA|NA	L	Involved in DNA repair and RecF pathway recombination
MAG.T21.18_00023	929556.Solca_3240	6.9e-229	800.4	Sphingobacteriia	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143				ko00000,ko00001,ko01000,ko01002				Bacteria	1IQQY@117747,4NEQS@976,COG1770@1,COG1770@2	NA|NA|NA	E	Peptidase S9, prolyl oligopeptidase, catalytic domain
MAG.T21.18_00026	1408473.JHXO01000001_gene2290	1.6e-47	196.8	Bacteroidia	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2FNVF@200643,4NGEV@976,COG0322@1,COG0322@2	NA|NA|NA	L	COG NOG11654 non supervised orthologous group
MAG.T21.18_00027	926562.Oweho_2456	1.7e-103	383.3	Cryomorphaceae	mltD			ko:K08307,ko:K12204					ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1			Bacteria	1HYXP@117743,2PACQ@246874,4NEKW@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2	NA|NA|NA	M	Transglycosylase SLT domain
MAG.T21.18_00028	755732.Fluta_1464	4.6e-154	551.2	Cryomorphaceae	gatA		6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	1HXBS@117743,2PA8A@246874,4NF8C@976,COG0154@1,COG0154@2	NA|NA|NA	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAG.T21.18_00029	1127692.HMPREF9075_01557	3.8e-11	73.6	Capnocytophaga	tatA			ko:K03116	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1ESFF@1016,1I54R@117743,4NUNH@976,COG1826@1,COG1826@2	NA|NA|NA	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MAG.T21.18_00030	755732.Fluta_1631	1.2e-52	214.2	Cryomorphaceae	envC												Bacteria	1HWW3@117743,2PAWC@246874,4NH2T@976,COG4942@1,COG4942@2	NA|NA|NA	D	Peptidase family M23
MAG.T21.18_00031	742817.HMPREF9449_02429	1.3e-16	94.0	Bacteria													Bacteria	2C1B9@1,32R9M@2	NA|NA|NA	S	Domain of unknown function (DUF4292)
MAG.T21.18_00032	929556.Solca_4341	9.1e-91	341.3	Sphingobacteriia													Bacteria	1IR0N@117747,4NDVW@976,COG0457@1,COG0457@2	NA|NA|NA	S	PFAM Tetratricopeptide
MAG.T21.18_00033	1107311.Q767_11445	2.4e-101	375.6	Flavobacterium			2.3.1.157,2.7.7.23,2.7.7.24	ko:K00973,ko:K04042	ko00520,ko00521,ko00523,ko00525,ko01100,ko01130,map00520,map00521,map00523,map00525,map01100,map01130	M00362,M00793	R00416,R02328,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000				Bacteria	1IJF6@117743,2P0PR@237,4PKUB@976,COG1209@1,COG1209@2	NA|NA|NA	M	Nucleotidyl transferase
MAG.T21.18_00034	667015.Bacsa_1919	5.9e-50	203.8	Bacteroidaceae	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	2FR7A@200643,4AP3D@815,4NNI4@976,COG0756@1,COG0756@2	NA|NA|NA	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MAG.T21.18_00035	686340.Metal_0735	1.9e-105	389.8	Methylococcales	cap												Bacteria	1R512@1224,1RZ0F@1236,1XE8D@135618,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
MAG.T21.18_00036	1123008.KB905694_gene1721	5.2e-23	113.6	Bacteroidia				ko:K19092					ko00000,ko02048				Bacteria	2G03Q@200643,4NQ43@976,COG3668@1,COG3668@2	NA|NA|NA	S	ParE toxin of type II toxin-antitoxin system, parDE
MAG.T21.18_00037	1121286.AUMT01000003_gene2122	7e-21	106.3	Chryseobacterium				ko:K07746					ko00000,ko02048				Bacteria	1I46W@117743,3ZSXX@59732,4NSHD@976,COG3609@1,COG3609@2	NA|NA|NA	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
MAG.T21.18_00038	1317124.DW2_03604	4.9e-36	158.7	Alphaproteobacteria													Bacteria	1NTWC@1224,2EXSJ@1,2UPGU@28211,33R1U@2	NA|NA|NA		
MAG.T21.18_00040	385682.AFSL01000053_gene460	2e-121	444.1	Marinilabiliaceae	zraS_1												Bacteria	2FRVJ@200643,3XIZ5@558415,4NE49@976,COG5000@1,COG5000@2	NA|NA|NA	T	GHKL domain
MAG.T21.18_00041	153721.MYP_3535	0.0	2304.2	Cytophagia			3.2.1.89	ko:K01224					ko00000,ko01000				Bacteria	47Q40@768503,4PHTS@976,COG2152@1,COG2152@2,COG3291@1,COG3291@2,COG4932@1,COG4932@2	NA|NA|NA	M	Leucine-rich repeat (LRR) protein
MAG.T21.18_00042	700598.Niako_4554	1.7e-38	166.8	Sphingobacteriia				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	1IQ3Y@117747,4NIU4@976,COG2067@1,COG2067@2	NA|NA|NA	I	protein CHP03519, membrane, Bacteroidetes
MAG.T21.18_00043	1484460.JSWG01000009_gene218	2e-86	325.9	Flavobacteriia	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	Bacteria	1HX6V@117743,4NECM@976,COG0224@1,COG0224@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAG.T21.18_00044	1453500.AT05_03545	4.6e-243	847.0	Flavobacteriia	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iSB619.SA_RS10975	Bacteria	1HXGV@117743,4NFZW@976,COG0056@1,COG0056@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAG.T21.18_00045	1124780.ANNU01000006_gene2924	8e-41	173.7	Cytophagia	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	Bacteria	47QGS@768503,4NSNF@976,COG0712@1,COG0712@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAG.T21.18_00046	926562.Oweho_2371	1.5e-30	139.4	Cryomorphaceae	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664	Bacteria	1I239@117743,2PB2M@246874,4NQKA@976,COG0711@1,COG0711@2	NA|NA|NA	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAG.T21.18_00047	760192.Halhy_3256	2.2e-11	74.7	Sphingobacteriia	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iHN637.CLJU_RS01165	Bacteria	1ITY0@117747,4NURW@976,COG0636@1,COG0636@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAG.T21.18_00048	1408813.AYMG01000014_gene1578	6.8e-92	344.4	Sphingobacteriia	atpB			ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1			Bacteria	1IPTF@117747,4NEPK@976,COG0356@1,COG0356@2	NA|NA|NA	C	it plays a direct role in the translocation of protons across the membrane
MAG.T21.18_00051	886379.AEWI01000022_gene108	4.5e-26	124.4	Marinilabiliaceae													Bacteria	2FUPU@200643,3XK7D@558415,4NUZA@976,COG1664@1,COG1664@2	NA|NA|NA	M	Polymer-forming cytoskeletal
MAG.T21.18_00052	926562.Oweho_2365	1.3e-117	431.0	Flavobacteriia				ko:K02453	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	1IKHB@117743,4PKGA@976,COG1729@1,COG1729@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_00053	1189619.pgond44_12827	1.2e-54	220.3	Psychroflexus	nlpD_1												Bacteria	1HXBC@117743,4C3BQ@83612,4NFZN@976,COG0739@1,COG0739@2	NA|NA|NA	M	Peptidase family M23
MAG.T21.18_00054	929704.Myrod_1677	2.4e-169	602.1	Myroides													Bacteria	1HXTW@117743,47HCE@76831,4NDYR@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	GH3 auxin-responsive promoter
MAG.T21.18_00055	290397.Adeh_3146	1.6e-09	69.3	Bacteria													Bacteria	COG0723@1,COG0723@2	NA|NA|NA	C	oxidoreductase activity, acting on diphenols and related substances as donors
MAG.T21.18_00056	1121373.KB903643_gene3500	1.1e-93	350.1	Cytophagia	sua5	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	47KX9@768503,4NF5U@976,COG0009@1,COG0009@2	NA|NA|NA	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAG.T21.18_00057	1239962.C943_01996	8.9e-20	103.2	Cytophagia	arsC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537					ko00000,ko01000				Bacteria	47SWP@768503,4NXD1@976,COG1393@1,COG1393@2	NA|NA|NA	P	ArsC family
MAG.T21.18_00058	1121859.KB890760_gene2061	4.5e-147	527.7	Cytophagia	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	Bacteria	47K0A@768503,4NG0S@976,COG0743@1,COG0743@2	NA|NA|NA	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MAG.T21.18_00059	1408433.JHXV01000002_gene463	1.9e-125	456.1	Cryomorphaceae	rseP			ko:K11749	ko02024,ko04112,map02024,map04112				ko00000,ko00001,ko01000,ko01002				Bacteria	1HXEV@117743,2PAA1@246874,4NEAR@976,COG0750@1,COG0750@2	NA|NA|NA	M	Peptidase family M50
MAG.T21.18_00060	1045855.DSC_04335	2.1e-18	98.6	Xanthomonadales													Bacteria	1N0YI@1224,1RQQ3@1236,1X485@135614,COG0745@1,COG0745@2	NA|NA|NA	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.18_00061	1280380.KR100_02380	1.8e-14	87.4	Synechococcus			3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503		R06200,R11307,R11308		ko00000,ko00001,ko01000,ko01002		GH5,GH9		Bacteria	1G1I0@1117,1GZV9@1129,COG2931@1,COG2931@2,COG3420@1,COG3420@2	NA|NA|NA	Q	Hemolysin-type calcium-binding repeat (2 copies)
MAG.T21.18_00062	313596.RB2501_09025	1.5e-48	200.3	Flavobacteriia	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61	ko:K15461			R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016				Bacteria	1HWR8@117743,4NFCD@976,COG0665@1,COG0665@2	NA|NA|NA	E	fad dependent oxidoreductase
MAG.T21.18_00063	1120966.AUBU01000013_gene461	2.7e-255	888.6	Cytophagia				ko:K09800					ko00000,ko02000				Bacteria	47KTA@768503,4NHD3@976,COG2982@1,COG2982@2	NA|NA|NA	M	AsmA-like C-terminal region
MAG.T21.18_00064	313606.M23134_07479	0.0	1293.9	Cytophagia													Bacteria	47MEM@768503,4NED2@976,COG2373@1,COG2373@2	NA|NA|NA	S	Alpha-2-macroglobulin family
MAG.T21.18_00066	1111730.ATTM01000006_gene2615	6.4e-44	184.1	Flavobacterium				ko:K09164					ko00000				Bacteria	1I2RJ@117743,2NUQ6@237,4NNWJ@976,COG3358@1,COG3358@2	NA|NA|NA	S	Protein of unknown function (DUF1684)
MAG.T21.18_00067	927658.AJUM01000037_gene2191	3.6e-71	275.0	Marinilabiliaceae													Bacteria	29UMW@1,2G24N@200643,30FZE@2,3XJR5@558415,4NP3W@976	NA|NA|NA		
MAG.T21.18_00068	1249997.JHZW01000002_gene1112	1.2e-49	202.6	Maribacter	mce		5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000				Bacteria	1I1YS@117743,2PHQD@252356,4NNGG@976,COG0346@1,COG0346@2	NA|NA|NA	E	Glyoxalase-like domain
MAG.T21.18_00069	440512.C211_19634	5.9e-15	87.0	Bacteria				ko:K07343					ko00000				Bacteria	COG3070@1,COG3070@2	NA|NA|NA	K	positive regulation of type IV pilus biogenesis
MAG.T21.18_00070	1140.Synpcc7942_1005	6.6e-44	184.1	Cyanobacteria	yihX		3.1.3.10,3.8.1.2	ko:K01560,ko:K07025,ko:K20866	ko00010,ko00361,ko00625,ko01100,ko01120,map00010,map00361,map00625,map01100,map01120		R00947,R05287	RC00078,RC00697	ko00000,ko00001,ko01000				Bacteria	1G87B@1117,COG1011@1,COG1011@2	NA|NA|NA	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED
MAG.T21.18_00071	36874.HQ34_06930	9.7e-13	80.9	Bacteroidia													Bacteria	29A5Q@1,2FPGZ@200643,2ZX6Q@2,4NP43@976	NA|NA|NA		
MAG.T21.18_00073	1121373.KB903621_gene1893	6.1e-50	205.7	Bacteroidetes													Bacteria	4P3UD@976,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAG.T21.18_00074	761193.Runsl_2369	9.6e-112	410.2	Cytophagia	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	47JM5@768503,4NEM9@976,COG1087@1,COG1087@2	NA|NA|NA	M	PFAM NAD dependent epimerase dehydratase family
MAG.T21.18_00075	1227739.Hsw_0120	2.1e-18	99.4	Cytophagia													Bacteria	47PT7@768503,4NUPJ@976,COG0671@1,COG0671@2	NA|NA|NA	I	phosphoesterase, PA-phosphatase related
MAG.T21.18_00076	755732.Fluta_1775	1.5e-147	529.6	Cryomorphaceae	rpoN			ko:K03092	ko02020,ko05111,map02020,map05111				ko00000,ko00001,ko03021				Bacteria	1HX2W@117743,2PAMH@246874,4NE5B@976,COG1508@1,COG1508@2	NA|NA|NA	K	PFAM Sigma-54 factor, Activator interacting domain (AID)
MAG.T21.18_00077	1408433.JHXV01000018_gene3807	5.4e-38	166.4	Cryomorphaceae													Bacteria	1I891@117743,2E09V@1,2PA81@246874,32VXB@2,4NY12@976	NA|NA|NA		
MAG.T21.18_00078	1121899.Q764_08910	9e-30	136.3	Flavobacterium	yffB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1I450@117743,2NWAM@237,4NSAW@976,COG1393@1,COG1393@2	NA|NA|NA	P	Belongs to the ArsC family
MAG.T21.18_00079	926559.JoomaDRAFT_0554	2.3e-122	445.3	Flavobacteriia	ygiD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114	1.13.11.8	ko:K04100,ko:K15777	ko00362,ko00624,ko00627,ko00965,ko01120,map00362,map00624,map00627,map00965,map01120		R01632,R03550,R04280,R08836,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000				Bacteria	1HX1P@117743,4NFGT@976,COG3384@1,COG3384@2	NA|NA|NA	S	in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine
MAG.T21.18_00080	1408473.JHXO01000012_gene293	1.1e-61	243.0	Bacteroidia													Bacteria	2FVBK@200643,4NNMD@976,COG2353@1,COG2353@2	NA|NA|NA	S	YceI-like domain
MAG.T21.18_00081	1121898.Q766_16495	4e-93	347.8	Flavobacterium				ko:K06911					ko00000				Bacteria	1HYY2@117743,2NSN5@237,4NGJ5@976,COG1741@1,COG1741@2	NA|NA|NA	S	Belongs to the pirin family
MAG.T21.18_00082	1538644.KO02_14420	6.2e-90	337.4	Bacteroidetes													Bacteria	4NMRA@976,COG2207@1,COG2207@2	NA|NA|NA	K	transcriptional regulator (AraC family)
MAG.T21.18_00083	1237149.C900_05328	2.3e-64	252.7	Cytophagia	rbn			ko:K03303,ko:K07058					ko00000,ko02000	2.A.14			Bacteria	47MBC@768503,4NFG8@976,COG1295@1,COG1295@2	NA|NA|NA	S	Virulence factor BrkB
MAG.T21.18_00085	1492738.FEM21_19780	4.3e-23	114.0	Flavobacterium	hxlR												Bacteria	1I4BG@117743,2P07X@237,4NU8W@976,COG1733@1,COG1733@2	NA|NA|NA	K	HxlR-like helix-turn-helix
MAG.T21.18_00086	1408433.JHXV01000002_gene274	1.4e-87	329.7	Cryomorphaceae		GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944											Bacteria	1HX28@117743,2PBGB@246874,4NI0H@976,COG2761@1,COG2761@2	NA|NA|NA	Q	Thioredoxin
MAG.T21.18_00087	1121373.KB903663_gene1210	4.1e-73	282.7	Cytophagia													Bacteria	47YII@768503,4PP7E@976,COG0823@1,COG0823@2,COG3386@1,COG3386@2	NA|NA|NA	G	C-terminal domain of CHU protein family
MAG.T21.18_00088	1121012.AUKX01000009_gene2884	1.1e-21	109.8	Arenibacter				ko:K13993	ko04141,map04141				ko00000,ko00001,ko03110				Bacteria	1I382@117743,23HCK@178469,4NQXY@976,COG0071@1,COG0071@2	NA|NA|NA	O	Hsp20/alpha crystallin family
MAG.T21.18_00089	1408473.JHXO01000002_gene3904	3.1e-10	72.0	Bacteroidetes													Bacteria	2AU1F@1,31JMK@2,4NQUW@976	NA|NA|NA		
MAG.T21.18_00091	926562.Oweho_2780	1.9e-78	300.1	Cryomorphaceae													Bacteria	1HXJ9@117743,2PBC1@246874,4NEH3@976,COG1538@1,COG1538@2	NA|NA|NA	MU	Outer membrane efflux protein
MAG.T21.18_00092	1288963.ADIS_3702	5.9e-106	391.3	Cytophagia	cvaA												Bacteria	47JV7@768503,4NFEK@976,COG0845@1,COG0845@2	NA|NA|NA	M	Biotin-lipoyl like
MAG.T21.18_00093	1121931.AUHG01000012_gene2502	1.1e-141	510.4	Flavobacteriia				ko:K02021					ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	1HWYH@117743,4NFJF@976,COG2274@1,COG2274@2	NA|NA|NA	V	ABC transporter
MAG.T21.18_00094	686340.Metal_0288	2.1e-35	156.0	Bacteria													Bacteria	COG1309@1,COG1309@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.18_00095	143224.JQMD01000002_gene3726	8.4e-183	646.7	Flavobacteriia	asnS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iSDY_1059.SDY_2327	Bacteria	1HWYW@117743,4NDY4@976,COG0017@1,COG0017@2	NA|NA|NA	J	Asparaginyl-tRNA synthetase
MAG.T21.18_00096	755732.Fluta_1546	3.5e-68	265.0	Cryomorphaceae				ko:K07705	ko02020,map02020	M00492			ko00000,ko00001,ko00002,ko02022				Bacteria	1I0BK@117743,2PAUQ@246874,4NKXC@976,COG3279@1,COG3279@2	NA|NA|NA	K	Response regulator of the LytR AlgR family
MAG.T21.18_00097	218284.CCDN010000001_gene1426	6e-60	237.7	Bacillus	frnE												Bacteria	1TZ1N@1239,1ZD4M@1386,4HEBF@91061,COG2761@1,COG2761@2	NA|NA|NA	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis
MAG.T21.18_00098	926562.Oweho_0543	2.1e-84	320.5	Cryomorphaceae			4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYQY@117743,2PBN1@246874,4NEVN@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2	NA|NA|NA	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family
MAG.T21.18_00099	1121481.AUAS01000006_gene877	2e-211	743.4	Cytophagia													Bacteria	47S7V@768503,4NKIR@976,COG1520@1,COG1520@2,COG2931@1,COG2931@2,COG5184@1,COG5184@2	NA|NA|NA	Q	SMART Integrin alpha beta-propellor repeat protein
MAG.T21.18_00100	945713.IALB_0186	6.5e-40	173.3	Bacteria			3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503				ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2			Bacteria	COG4675@1,COG4675@2,COG5276@1,COG5276@2	NA|NA|NA	M	tail collar domain protein
MAG.T21.18_00101	926562.Oweho_2163	1.8e-14	85.9	Cryomorphaceae													Bacteria	1IG79@117743,29Y6M@1,2PB8M@246874,30K04@2,4PI08@976	NA|NA|NA		
MAG.T21.18_00102	945713.IALB_3157	1.2e-86	327.8	Bacteria													Bacteria	COG4733@1,COG4733@2	NA|NA|NA	S	cellulase activity
MAG.T21.18_00103	945713.IALB_3159	1.5e-184	654.8	Bacteria				ko:K02057		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	COG0419@1,COG0419@2	NA|NA|NA	L	ATPase involved in DNA repair
MAG.T21.18_00104	1168289.AJKI01000002_gene2519	1.2e-84	320.9	Marinilabiliaceae													Bacteria	2FX2H@200643,3XK71@558415,4NHCJ@976,COG3188@1,COG3188@2	NA|NA|NA	NU	usher protein
MAG.T21.18_00105	485918.Cpin_6992	5.4e-44	186.8	Bacteroidetes	xynX1		3.1.3.8	ko:K01083	ko00562,map00562		R03371	RC00078	ko00000,ko00001,ko01000				Bacteria	4NHFV@976,COG2374@1,COG2374@2	NA|NA|NA	O	PFAM SMP-30 Gluconolaconase
MAG.T21.18_00106	1122176.KB903563_gene3457	2.7e-47	196.1	Bacteroidetes			2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	4NKVR@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_00107	1122179.KB890421_gene2551	2.5e-26	125.6	Bacteroidetes													Bacteria	4NKVR@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_00108	1122176.KB903563_gene3457	4.5e-70	272.3	Bacteroidetes			2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	4NKVR@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_00109	485918.Cpin_3102	3.6e-45	188.3	Sphingobacteriia													Bacteria	1ITQW@117747,4NHTM@976,COG2197@1,COG2197@2	NA|NA|NA	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.18_00110	761193.Runsl_3135	7.1e-30	139.4	Cytophagia													Bacteria	47Q3Z@768503,4NI1V@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_00111	700598.Niako_0691	1.6e-25	124.8	Bacteroidetes													Bacteria	4NI1V@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_00112	1408433.JHXV01000036_gene261	1.5e-38	166.4	Cryomorphaceae				ko:K09017					ko00000,ko03000				Bacteria	1I0I9@117743,2PBX4@246874,4NQ99@976,COG1309@1,COG1309@2	NA|NA|NA	K	Bacterial regulatory proteins, tetR family
MAG.T21.18_00113	1122179.KB890436_gene1412	4.5e-15	89.7	Sphingobacteriia		GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	3.2.1.35,3.2.1.96	ko:K01197,ko:K01227	ko00511,ko00531,ko01100,map00511,map00531,map01100	M00076,M00077	R07824,R07825,R10905		ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042				Bacteria	1IWYC@117747,4NEAB@976,COG1361@1,COG1361@2,COG3055@1,COG3055@2,COG3291@1,COG3291@2,COG5492@1,COG5492@2	NA|NA|NA	N	Domain of unknown function (DUF5060)
MAG.T21.18_00115	755732.Fluta_3404	1.3e-183	649.4	Cryomorphaceae	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12,4.1.1.32	ko:K00134,ko:K01596	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03320,ko04066,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,ko05010,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map03320,map04066,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R00431,R00726,R01061	RC00002,RC00149,RC02741	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147			iIT341.HP0921,iIT341.HP1346	Bacteria	1HXX7@117743,2PAGG@246874,4NG5C@976,COG0057@1,COG0057@2	NA|NA|NA	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
MAG.T21.18_00116	709991.Odosp_1601	1.2e-125	456.1	Porphyromonadaceae	rpoD			ko:K03086					ko00000,ko03021				Bacteria	22XDM@171551,2FNVQ@200643,4NEBF@976,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MAG.T21.18_00117	1168289.AJKI01000035_gene3580	7e-121	441.0	Marinilabiliaceae	htrA		3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	2FMUA@200643,3XJ0M@558415,4NFCS@976,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin
MAG.T21.18_00118	1166018.FAES_1877	2.2e-52	212.6	Cytophagia	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000			iIT341.HP0566,iLJ478.TM1522	Bacteria	47KR3@768503,4NF26@976,COG0253@1,COG0253@2	NA|NA|NA	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAG.T21.18_00119	1120965.AUBV01000005_gene1811	9.1e-75	287.3	Cytophagia	mltG			ko:K07082					ko00000				Bacteria	47J93@768503,4NG17@976,COG1559@1,COG1559@2	NA|NA|NA	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MAG.T21.18_00120	755732.Fluta_4067	7.6e-181	640.2	Cryomorphaceae	femD		5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWVH@117743,2PBCM@246874,4NG3H@976,COG1109@1,COG1109@2	NA|NA|NA	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
MAG.T21.18_00121	391603.FBALC1_10252	3.1e-66	258.8	Flavobacteriia	yfiM			ko:K05811					ko00000				Bacteria	1HZYF@117743,4NGNB@976,COG5544@1,COG5544@2	NA|NA|NA	S	Predicted periplasmic lipoprotein (DUF2279)
MAG.T21.18_00122	1408813.AYMG01000037_gene53	6.4e-54	217.2	Sphingobacteriia	nudF		3.6.1.13	ko:K01515	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000				Bacteria	1ISBJ@117747,4NMHV@976,COG0494@1,COG0494@2	NA|NA|NA	L	NUDIX domain
MAG.T21.18_00123	1227739.Hsw_0188	2.1e-19	102.8	Bacteria													Bacteria	COG0810@1,COG0810@2	NA|NA|NA	M	energy transducer activity
MAG.T21.18_00124	216432.CA2559_08606	2.2e-23	115.9	Flavobacteriia	mutS2			ko:K07456	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1I1ZP@117743,4NNNV@976,COG1193@1,COG1193@2	NA|NA|NA	L	DNA mismatch repair protein
MAG.T21.18_00125	1408433.JHXV01000005_gene2427	4.9e-27	128.3	Cryomorphaceae													Bacteria	1ICQT@117743,2BUW8@1,2PBTB@246874,32Q8B@2,4PBQS@976	NA|NA|NA		
MAG.T21.18_00126	485918.Cpin_1909	1.5e-41	176.8	Sphingobacteriia													Bacteria	1IP54@117747,2CA60@1,2Z88P@2,4NJRW@976	NA|NA|NA		
MAG.T21.18_00127	1168289.AJKI01000035_gene3567	7.6e-66	257.7	Marinilabiliaceae	btuC			ko:K02015	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	2FNDK@200643,3XIIQ@558415,4NEDU@976,COG0609@1,COG0609@2	NA|NA|NA	P	FecCD transport family
MAG.T21.18_00128	1227739.Hsw_PA0252	4.5e-50	204.9	Cytophagia	fecE		3.6.3.34	ko:K02013	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14			Bacteria	47KI0@768503,4NG1Q@976,COG1120@1,COG1120@2	NA|NA|NA	HP	ABC transporter
MAG.T21.18_00129	1380384.JADN01000004_gene2378	5.9e-33	147.1	Flavobacteriia	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066		ko:K03282					ko00000,ko02000	1.A.22.1			Bacteria	1I33I@117743,4NQ49@976,COG1970@1,COG1970@2	NA|NA|NA	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MAG.T21.18_00130	1453498.LG45_03095	2.1e-14	85.9	Flavobacterium													Bacteria	1I5PD@117743,2NU9F@237,4NR5W@976,COG2350@1,COG2350@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.18_00131	502025.Hoch_5175	2.4e-24	118.6	Myxococcales	fcbC			ko:K07107					ko00000,ko01000				Bacteria	1MZTU@1224,2WT0J@28221,2Z1TJ@29,42WZM@68525,COG0824@1,COG0824@2	NA|NA|NA	S	Thioesterase-like superfamily
MAG.T21.18_00132	1408433.JHXV01000006_gene2720	5e-89	335.5	Cryomorphaceae													Bacteria	1IKD1@117743,2PAST@246874,4NEPG@976,COG5107@1,COG5107@2	NA|NA|NA	A	Domain of Unknown Function (DUF349)
MAG.T21.18_00133	1313301.AUGC01000003_gene1975	3.1e-52	213.0	Bacteroidetes	rsbP		3.1.3.3	ko:K02660,ko:K07315,ko:K17763	ko02020,ko02025,map02020,map02025				ko00000,ko00001,ko01000,ko02035,ko02044,ko03021				Bacteria	4NIXZ@976,COG2202@1,COG2202@2,COG2203@1,COG2203@2,COG2208@1,COG2208@2	NA|NA|NA	T	Sigma factor PP2C-like phosphatases
MAG.T21.18_00134	1124780.ANNU01000048_gene2121	6e-214	750.4	Cytophagia	pruA		1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100		R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000				Bacteria	47JZ2@768503,4NFTW@976,COG1012@1,COG1012@2	NA|NA|NA	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1
MAG.T21.18_00135	1267211.KI669560_gene370	1.3e-79	302.8	Sphingobacteriia	ybcF		4.2.1.1	ko:K01673	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000			iNJ661.Rv3273	Bacteria	1IQ7Q@117747,4NEJT@976,COG0288@1,COG0288@2	NA|NA|NA	P	Reversible hydration of carbon dioxide
MAG.T21.18_00136	926562.Oweho_0570	3.6e-142	511.9	Cryomorphaceae	ychM			ko:K03321					ko00000,ko02000	2.A.53.3			Bacteria	1HYXB@117743,2PAJA@246874,4NE9G@976,COG0659@1,COG0659@2	NA|NA|NA	P	PFAM Sulfate transporter family
MAG.T21.18_00138	1356852.N008_13700	5.5e-27	127.1	Cytophagia	apaG			ko:K06195					ko00000				Bacteria	47PP3@768503,4NNRA@976,COG2967@1,COG2967@2	NA|NA|NA	P	protein affecting Mg2 Co2 transport
MAG.T21.18_00139	1484460.JSWG01000009_gene275	1.7e-33	150.2	Bacteria			3.4.24.40	ko:K01406	ko01503,map01503				ko00000,ko00001,ko01000,ko01002				Bacteria	COG3391@1,COG3391@2	NA|NA|NA	CO	amine dehydrogenase activity
MAG.T21.18_00141	1121896.JMLU01000003_gene2231	5.3e-41	176.4	Flavobacterium	bhp												Bacteria	1IKR6@117743,2P0US@237,4NDZQ@976,COG3291@1,COG3291@2,COG4935@1,COG4935@2,COG5492@1,COG5492@2,COG5604@1,COG5604@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.18_00142	926562.Oweho_3400	1.9e-80	306.6	Flavobacteriia													Bacteria	1HY3Q@117743,28HE2@1,2Z7QJ@2,4NFBA@976	NA|NA|NA	S	Domain of unknown function (DUF5103)
MAG.T21.18_00143	1408433.JHXV01000001_gene920	4.5e-144	518.1	Cryomorphaceae	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346					ko00000,ko01000				Bacteria	1HWV3@117743,2PBAX@246874,4NEDQ@976,COG1726@1,COG1726@2	NA|NA|NA	C	Na(+)-translocating NADH-quinone reductase subunit A (NQRA)
MAG.T21.18_00144	1189620.AJXL01000030_gene2805	1.8e-138	499.2	Flavobacterium	nqrB		1.6.5.8	ko:K00347					ko00000,ko01000				Bacteria	1HXYV@117743,2NVU4@237,4NFGW@976,COG4658@1,COG4658@2	NA|NA|NA	C	NQR2, RnfD, RnfE family
MAG.T21.18_00145	1189620.AJXL01000030_gene2806	7.8e-48	197.6	Flavobacterium	nqrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.6.5.8	ko:K00348					ko00000,ko01000				Bacteria	1HZG0@117743,2NWMX@237,4NF7A@976,COG2869@1,COG2869@2	NA|NA|NA	C	FMN_bind
MAG.T21.18_00146	926562.Oweho_3404	9.5e-81	306.6	Cryomorphaceae	nqrD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.8	ko:K00349					ko00000,ko01000				Bacteria	1HXGP@117743,2PBGM@246874,4NGD9@976,COG1347@1,COG1347@2	NA|NA|NA	C	Rnf-Nqr subunit, membrane protein
MAG.T21.18_00147	926562.Oweho_3405	6.6e-81	307.0	Cryomorphaceae	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350					ko00000,ko01000				Bacteria	1HX59@117743,2PBFJ@246874,4NEU0@976,COG2209@1,COG2209@2	NA|NA|NA	C	Rnf-Nqr subunit, membrane protein
MAG.T21.18_00148	1453500.AT05_07580	4.7e-201	707.2	Flavobacteriia	nqrF		1.6.5.8	ko:K00351					ko00000,ko01000				Bacteria	1HWV9@117743,4NFKC@976,COG2871@1,COG2871@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
MAG.T21.18_00149	1453500.AT05_07585	8.9e-57	227.6	Flavobacteriia	apbE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564	1.8.1.2,2.7.1.180	ko:K00380,ko:K03734	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXDG@117743,4NGEK@976,COG1477@1,COG1477@2	NA|NA|NA	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAG.T21.18_00150	755732.Fluta_0646	5.6e-178	630.6	Cryomorphaceae	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441			R10652	RC00003,RC03217	ko00000,ko01000,ko03009				Bacteria	1HXRF@117743,2PAK2@246874,4NEJK@976,COG0621@1,COG0621@2	NA|NA|NA	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
MAG.T21.18_00151	1227739.Hsw_4210	5.3e-47	195.7	Bacteria													Bacteria	COG3391@1,COG3391@2	NA|NA|NA	CO	amine dehydrogenase activity
MAG.T21.18_00152	1121889.AUDM01000002_gene448	7.6e-74	285.4	Flavobacteriia	xadA			ko:K15125,ko:K21449	ko05133,map05133				ko00000,ko00001,ko00536,ko02000	1.B.40.2			Bacteria	1HZNB@117743,4NJTK@976,COG3210@1,COG3210@2,COG4675@1,COG4675@2,COG5295@1,COG5295@2	NA|NA|NA	UW	surface antigen
MAG.T21.18_00153	485918.Cpin_3102	2.4e-41	175.6	Sphingobacteriia													Bacteria	1ITQW@117747,4NHTM@976,COG2197@1,COG2197@2	NA|NA|NA	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.18_00154	1122179.KB890461_gene2164	4.6e-29	136.3	Bacteroidetes													Bacteria	4NS8E@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_00155	497964.CfE428DRAFT_5731	3.2e-46	191.8	Verrucomicrobia													Bacteria	46UBU@74201,COG2197@1,COG2197@2	NA|NA|NA	T	PFAM regulatory protein LuxR
MAG.T21.18_00156	755732.Fluta_4062	8.6e-52	212.6	Flavobacteriia			2.7.13.3	ko:K07778	ko02020,map02020	M00479			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1IINS@117743,4NPAJ@976,COG3292@1,COG3292@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_00157	929556.Solca_3976	2.6e-124	452.6	Sphingobacteriia													Bacteria	1INPA@117747,4NGK1@976,COG4870@1,COG4870@2	NA|NA|NA	O	Papain family cysteine protease
MAG.T21.18_00158	1122179.KB890451_gene4532	2.9e-38	167.2	Bacteria													Bacteria	COG3210@1,COG3210@2	NA|NA|NA	U	domain, Protein
MAG.T21.18_00159	1408433.JHXV01000001_gene1029	1.2e-31	143.7	Cryomorphaceae													Bacteria	1ICSQ@117743,2BPRN@1,2PC0H@246874,32IIX@2,4PEDZ@976	NA|NA|NA		
MAG.T21.18_00161	1408433.JHXV01000001_gene1031	5.1e-54	217.6	Cryomorphaceae	ydjA												Bacteria	1I1BE@117743,2PB0W@246874,4NMUE@976,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase family
MAG.T21.18_00163	880070.Cycma_5098	5.6e-21	107.8	Bacteroidetes				ko:K07052					ko00000				Bacteria	2E9TR@1,333ZQ@2,4NVUY@976	NA|NA|NA	S	CAAX protease self-immunity
MAG.T21.18_00165	992406.RIA_1376	7.5e-107	393.7	Flavobacteriia													Bacteria	1HWS3@117743,4NE45@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	short-chain dehydrogenase
MAG.T21.18_00166	1121904.ARBP01000007_gene3099	4.8e-34	151.8	Cytophagia	CP_1117		2.1.1.294,2.7.1.181	ko:K18827			R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005				Bacteria	47WA7@768503,4NMT7@976,COG4372@1,COG4372@2	NA|NA|NA	S	Transposase
MAG.T21.18_00168	385682.AFSL01000003_gene1912	6.3e-21	107.1	Marinilabiliaceae													Bacteria	2AD7J@1,2G24U@200643,312WH@2,3XK3Q@558415,4NR1A@976	NA|NA|NA	S	Domain of unknown function (DUF1987)
MAG.T21.18_00169	1408433.JHXV01000038_gene2198	1.4e-95	357.5	Bacteroidetes													Bacteria	4NRRF@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_00171	45351.EDO26512	2.1e-89	335.5	Opisthokonta													Opisthokonta	2QT54@2759,3AN9F@33154,COG1611@1	NA|NA|NA	S	Possible lysine decarboxylase
MAG.T21.18_00172	1250232.JQNJ01000001_gene3467	0.0	1199.1	Flavobacteriia	uvrA			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1HXMR@117743,4NFQU@976,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAG.T21.18_00173	927658.AJUM01000022_gene979	6.1e-89	334.3	Marinilabiliaceae	mltD_2												Bacteria	2FM9R@200643,3XJI8@558415,4NH4W@976,COG0741@1,COG0741@2	NA|NA|NA	M	Transglycosylase SLT domain
MAG.T21.18_00174	755732.Fluta_2051	1.3e-58	233.8	Cryomorphaceae			2.7.8.33,2.7.8.35	ko:K02851			R08856	RC00002	ko00000,ko01000,ko01003,ko01005				Bacteria	1HZEV@117743,2PBMM@246874,4NGKM@976,COG0472@1,COG0472@2	NA|NA|NA	M	Glycosyl transferase family 4
MAG.T21.18_00175	926549.KI421517_gene591	2.6e-49	201.8	Cytophagia	rfbC		5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	47PQR@768503,4NNKW@976,COG1898@1,COG1898@2	NA|NA|NA	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MAG.T21.18_00176	1408433.JHXV01000044_gene3184	8.2e-130	471.5	Cryomorphaceae	wzc	GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576		ko:K16692					ko00000,ko01000,ko01001				Bacteria	1HXKJ@117743,2PA6D@246874,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2	NA|NA|NA	DM	Chain length determinant protein
MAG.T21.18_00177	1408433.JHXV01000044_gene3183	1.3e-52	213.4	Cryomorphaceae				ko:K01991	ko02026,map02026				ko00000,ko00001,ko02000	1.B.18			Bacteria	1ICQF@117743,2PBRF@246874,4NPJB@976,COG1596@1,COG1596@2	NA|NA|NA	M	Polysaccharide biosynthesis/export protein
MAG.T21.18_00178	1122605.KB893647_gene420	2.2e-107	396.0	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.18_00179	1279009.ADICEAN_02019	3.2e-142	512.3	Cytophagia			6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	47JSF@768503,4NFQ3@976,COG0367@1,COG0367@2	NA|NA|NA	E	Asparagine synthase
MAG.T21.18_00180	96561.Dole_0976	2.5e-11	75.1	delta/epsilon subdivisions													Bacteria	1NF9M@1224,2CH0Y@1,3309M@2,42VBP@68525	NA|NA|NA		
MAG.T21.18_00181	1189612.A33Q_3001	2.8e-09	67.0	Cytophagia													Bacteria	2EGPU@1,33AFZ@2,47S90@768503,4NXYH@976	NA|NA|NA		
MAG.T21.18_00182	761193.Runsl_3794	9.2e-235	819.7	Cytophagia	nolO			ko:K00612					ko00000,ko01000				Bacteria	47JR5@768503,4NEV9@976,COG2192@1,COG2192@2	NA|NA|NA	O	PFAM Carbamoyltransferase
MAG.T21.18_00183	926556.Echvi_4609	2.3e-206	724.9	Cytophagia	lpdA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	47JS2@768503,4NDVC@976,COG1249@1,COG1249@2	NA|NA|NA	C	dihydrolipoamide dehydrogenase
MAG.T21.18_00184	649349.Lbys_0225	5e-15	87.8	Cytophagia													Bacteria	2CBZZ@1,32QA1@2,47QN2@768503,4NQPJ@976	NA|NA|NA		
MAG.T21.18_00185	1313421.JHBV01000043_gene3172	5.9e-64	251.1	Sphingobacteriia				ko:K07017					ko00000				Bacteria	1IWWR@117747,4NGAG@976,COG2819@1,COG2819@2	NA|NA|NA	S	Putative esterase
MAG.T21.18_00186	485917.Phep_0156	2e-27	128.6	Sphingobacteriia	tdcF		3.5.99.10	ko:K09022			R11098,R11099	RC03275,RC03354	ko00000,ko01000				Bacteria	1ISZW@117747,4NQ8M@976,COG0251@1,COG0251@2	NA|NA|NA	J	endoribonuclease L-PSP
MAG.T21.18_00187	1168289.AJKI01000012_gene310	3.1e-40	172.6	Bacteroidetes	tuaG	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.305	ko:K16698,ko:K21363					ko00000,ko01000,ko01003,ko01005		GT2		Bacteria	4NRHZ@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_00188	1380394.JADL01000007_gene4620	1.4e-102	380.6	Rhodospirillales			6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	1MW4E@1224,2JQXF@204441,2TSCY@28211,COG0367@1,COG0367@2	NA|NA|NA	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)
MAG.T21.18_00189	1346330.M472_15025	1.1e-88	333.2	Sphingobacteriia	surE		3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1IP3M@117747,4NEJ5@976,COG0496@1,COG0496@2	NA|NA|NA	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MAG.T21.18_00191	929713.NIASO_18530	8.3e-106	390.6	Sphingobacteriia	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005		GT19		Bacteria	1IPZM@117747,4NDW3@976,COG0763@1,COG0763@2	NA|NA|NA	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAG.T21.18_00192	755732.Fluta_1203	2.4e-58	233.0	Cryomorphaceae	lytB	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464		ko:K06381					ko00000				Bacteria	1I7GW@117743,2PAW4@246874,4NG21@976,COG2385@1,COG2385@2	NA|NA|NA	D	Stage II sporulation protein
MAG.T21.18_00193	696281.Desru_1792	1.8e-106	392.9	Peptococcaceae	rlmI		2.1.1.191,2.1.1.72	ko:K00571,ko:K06969					ko00000,ko01000,ko02048,ko03009				Bacteria	1TRAJ@1239,247TI@186801,261AH@186807,COG1092@1,COG1092@2	NA|NA|NA	J	SAM-dependent methyltransferase
MAG.T21.18_00194	330214.NIDE2695	4.5e-31	142.5	Bacteria				ko:K20306					ko00000,ko04131				Bacteria	COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
MAG.T21.18_00195	1120966.AUBU01000002_gene2016	2.8e-46	193.7	Cytophagia	comEC			ko:K02238		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	47K9X@768503,4NEJH@976,COG0658@1,COG0658@2	NA|NA|NA	S	TIGRFAM ComEC Rec2-related protein
MAG.T21.18_00196	525373.HMPREF0766_13567	1.4e-113	416.0	Sphingobacteriia	ytnP												Bacteria	1INUA@117747,4NE98@976,COG0491@1,COG0491@2	NA|NA|NA	S	beta-lactamase
MAG.T21.18_00197	1120951.AUBG01000006_gene460	2.2e-153	548.9	Flavobacteriia	murC		6.3.2.4,6.3.2.45,6.3.2.8	ko:K01921,ko:K01924,ko:K02558	ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502		R01150,R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1HXZ0@117743,4NF99@976,COG0773@1,COG0773@2	NA|NA|NA	M	Peptidoglycan synthetase
MAG.T21.18_00199	1380600.AUYN01000009_gene1739	4.4e-33	147.5	Flavobacteriia													Bacteria	1I2SM@117743,2AFHA@1,315HT@2,4NQ5F@976	NA|NA|NA	S	S23 ribosomal protein
MAG.T21.18_00200	755732.Fluta_3632	1.1e-171	610.1	Cryomorphaceae	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576		ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021				Bacteria	1HX0N@117743,2PA7C@246874,4NEFP@976,COG1158@1,COG1158@2	NA|NA|NA	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MAG.T21.18_00201	1120968.AUBX01000017_gene1889	8.8e-09	67.0	Cytophagia													Bacteria	2AVDM@1,31M58@2,47RZW@768503,4P9SJ@976	NA|NA|NA	S	Domain of unknown function (DUF4293)
MAG.T21.18_00202	1121957.ATVL01000010_gene234	5.4e-80	304.3	Cytophagia			4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000				Bacteria	47MIJ@768503,4NEH4@976,COG1024@1,COG1024@2	NA|NA|NA	I	Enoyl-CoA hydratase/isomerase
MAG.T21.18_00203	929562.Emtol_0629	1.1e-82	313.2	Cytophagia				ko:K02477					ko00000,ko02022				Bacteria	47N62@768503,4NFWA@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator of the LytR AlgR family
MAG.T21.18_00204	1124780.ANNU01000006_gene2947	2.9e-55	222.6	Cytophagia													Bacteria	47K66@768503,4NI09@976,COG2972@1,COG2972@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_00205	1223410.KN050846_gene331	9.1e-40	170.2	Flavobacteriia	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770		R01623		ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	Bacteria	1I1CI@117743,4NHQK@976,COG3124@1,COG3124@2	NA|NA|NA	S	phosphodiesterase
MAG.T21.18_00206	517418.Ctha_0374	5.4e-41	175.6	Chlorobi	mltF			ko:K18691					ko00000,ko01000,ko01011				Bacteria	1FEDF@1090,COG4623@1,COG4623@2	NA|NA|NA	M	Bacterial periplasmic substrate-binding proteins
MAG.T21.18_00207	880073.Calab_2100	1.4e-131	476.9	Bacteria			3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100		R01416	RC00177	ko00000,ko00001,ko01000				Bacteria	COG2957@1,COG2957@2	NA|NA|NA	E	agmatine deiminase activity
MAG.T21.18_00208	1304885.AUEY01000028_gene2795	1.4e-19	103.2	Proteobacteria													Bacteria	1QV5J@1224,COG4339@1,COG4339@2	NA|NA|NA	S	protein conserved in bacteria
MAG.T21.18_00209	925409.KI911562_gene1163	1e-133	483.8	Sphingobacteriia													Bacteria	1IPWT@117747,4NFFC@976,COG4102@1,COG4102@2	NA|NA|NA	S	Protein of unknown function (DUF1501)
MAG.T21.18_00210	1267211.KI669560_gene865	1.4e-104	387.1	Sphingobacteriia													Bacteria	1IQIN@117747,4NHSB@976,COG5267@1,COG5267@2	NA|NA|NA	S	Protein of unknown function (DUF1800)
MAG.T21.18_00211	426355.Mrad2831_0981	5.8e-14	84.7	Methylobacteriaceae			2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000				Bacteria	1JUE8@119045,1RKQD@1224,2UAAJ@28211,COG0500@1,COG2226@2	NA|NA|NA	Q	Protein of unknown function (DUF1698)
MAG.T21.18_00212	869213.JCM21142_104319	6.7e-81	307.4	Cytophagia	exoA		3.1.11.2	ko:K01142	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	47THR@768503,4NEY3@976,COG0708@1,COG0708@2	NA|NA|NA	L	Endonuclease/Exonuclease/phosphatase family
MAG.T21.18_00213	491205.JARQ01000001_gene501	1.2e-25	122.9	Chryseobacterium													Bacteria	1I2Z7@117743,2CWCM@1,32SZF@2,3ZS20@59732,4NSAZ@976	NA|NA|NA	S	Domain of unknown function (DUF4260)
MAG.T21.18_00214	760192.Halhy_1057	5.1e-39	167.2	Sphingobacteriia				ko:K06996					ko00000				Bacteria	1IT82@117747,4NSBC@976,COG3324@1,COG3324@2	NA|NA|NA	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAG.T21.18_00215	470145.BACCOP_03998	1.1e-48	199.9	Bacteroidaceae	trpG		2.4.2.18,2.6.1.85,4.1.3.27	ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	2FM5F@200643,4AMY7@815,4NE4I@976,COG0512@1,COG0512@2	NA|NA|NA	EH	Glutamine amidotransferase, class I
MAG.T21.18_00216	1313301.AUGC01000004_gene2236	7.1e-32	144.8	Bacteria			1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214				ko00000,ko00001,ko01000,ko01002,ko04147				Bacteria	COG1225@1,COG1225@2	NA|NA|NA	O	peroxiredoxin activity
MAG.T21.18_00217	1313301.AUGC01000004_gene2235	7.6e-71	274.6	Bacteria	srrB												Bacteria	COG2208@1,COG2208@2	NA|NA|NA	T	phosphoserine phosphatase activity
MAG.T21.18_00218	880526.KE386488_gene1899	5.6e-84	317.8	Rikenellaceae	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110		R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016				Bacteria	22U40@171550,2FNES@200643,4NEAE@976,COG0324@1,COG0324@2	NA|NA|NA	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAG.T21.18_00220	926559.JoomaDRAFT_3222	6.5e-23	113.6	Flavobacteriia													Bacteria	1I189@117743,29CCT@1,2ZZB9@2,4NM9K@976	NA|NA|NA	S	Pfam Plasmid pRiA4b ORF-3-like protein
MAG.T21.18_00221	1124780.ANNU01000065_gene456	1.7e-175	622.5	Cytophagia	cca		2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018		R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019				Bacteria	47KFG@768503,4NF1S@976,COG0617@1,COG0617@2	NA|NA|NA	J	Poly A polymerase head domain
MAG.T21.18_00223	1122201.AUAZ01000037_gene3834	2.4e-49	201.8	Alteromonadaceae	paaD	GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575		ko:K02612	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001			iECSE_1348.ECSE_1476	Bacteria	1RF3S@1224,1S4FY@1236,46ARE@72275,COG2151@1,COG2151@2	NA|NA|NA	L	metal-sulfur cluster biosynthetic enzyme
MAG.T21.18_00224	1411123.JQNH01000001_gene1832	1.2e-87	329.7	Alphaproteobacteria	paaC		1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001,ko01000				Bacteria	1MVYQ@1224,2TRYF@28211,COG3396@1,COG3396@2	NA|NA|NA	S	phenylacetic acid degradation protein
MAG.T21.18_00225	1121957.ATVL01000010_gene240	2.2e-34	151.4	Bacteroidetes	paaB			ko:K02610	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	4NQFV@976,COG3460@1,COG3460@2	NA|NA|NA	Q	Phenylacetate-CoA oxygenase
MAG.T21.18_00226	1313421.JHBV01000008_gene4327	6.9e-146	523.5	Sphingobacteriia	paaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001,ko01000			iEC55989_1330.EC55989_1524,iECO111_1330.ECO111_1782,iECO26_1355.ECO26_1992,iEcE24377_1341.EcE24377A_1573	Bacteria	1IVM8@117747,4NFJN@976,COG3396@1,COG3396@2	NA|NA|NA	S	Phenylacetic acid catabolic protein
MAG.T21.18_00227	926562.Oweho_2268	2.8e-98	365.5	Cryomorphaceae	paaE			ko:K02613	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1HX5B@117743,2PA8I@246874,4NF24@976,COG1018@1,COG1018@2	NA|NA|NA	C	PFAM 2Fe-2S iron-sulfur cluster binding domain
MAG.T21.18_00229	709986.Deima_2226	1.3e-61	244.2	Bacteria			2.7.13.3	ko:K11527					ko00000,ko01000,ko01001,ko02022				Bacteria	COG3437@1,COG3437@2,COG4251@1,COG4251@2	NA|NA|NA	T	response regulator, receiver
MAG.T21.18_00230	509635.N824_03095	1.1e-138	500.7	Sphingobacteriia	pgtB												Bacteria	1IQHK@117747,4NEJX@976,COG4191@1,COG4191@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_00231	388413.ALPR1_07485	3.6e-25	122.1	Cytophagia													Bacteria	28IFK@1,2Z8HB@2,47NVI@768503,4NH1P@976	NA|NA|NA		
MAG.T21.18_00232	509635.N824_03085	2.3e-166	592.8	Sphingobacteriia	moeY			ko:K02453	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	1IPCC@117747,4NHWN@976,COG0476@1,COG0476@2,COG0778@1,COG0778@2	NA|NA|NA	H	UBA THIF-type NAD FAD binding
MAG.T21.18_00233	929713.NIASO_00035	4e-27	127.9	Sphingobacteriia													Bacteria	1ISQ7@117747,4NP14@976,COG3437@1,COG3437@2	NA|NA|NA	T	cheY-homologous receiver domain
MAG.T21.18_00234	926562.Oweho_0783	3.7e-91	342.4	Cryomorphaceae	bshC			ko:K22136					ko00000				Bacteria	1HXWQ@117743,2PANK@246874,4NGCF@976,COG4365@1,COG4365@2	NA|NA|NA	S	Bacillithiol biosynthesis BshC
MAG.T21.18_00235	927658.AJUM01000047_gene2810	3.9e-208	731.1	Marinilabiliaceae	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009			iLJ478.TM1820	Bacteria	2FM3V@200643,3XJRE@558415,4NESX@976,COG0519@1,COG0519@2	NA|NA|NA	F	GMP synthase C terminal domain
MAG.T21.18_00236	1408433.JHXV01000001_gene1062	9.3e-43	181.8	Cryomorphaceae	ratA		3.5.1.28	ko:K01449,ko:K01999,ko:K13735	ko02010,ko02024,ko05100,map02010,map02024,map05100	M00237	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4			Bacteria	1HY84@117743,2PB0J@246874,4NG96@976,COG0683@1,COG0683@2,COG1388@1,COG1388@2	NA|NA|NA	EM	Lysin motif
MAG.T21.18_00237	1279009.ADICEAN_03831	2.7e-125	455.3	Cytophagia			1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100		R07063	RC00917	ko00000,ko00001,ko01000,ko01004				Bacteria	47JP1@768503,4NERD@976,COG3239@1,COG3239@2	NA|NA|NA	I	fatty acid desaturase
MAG.T21.18_00238	1280950.HJO_10164	5e-11	73.9	Alphaproteobacteria													Bacteria	1REJV@1224,2U8BB@28211,COG3801@1,COG3801@2	NA|NA|NA	S	YjbR
MAG.T21.18_00240	857087.Metme_3122	4.5e-15	88.2	Gammaproteobacteria													Bacteria	1NJ85@1224,1SQVJ@1236,2DWHQ@1,32V1N@2	NA|NA|NA		
MAG.T21.18_00241	1313421.JHBV01000003_gene659	0.0	1170.2	Sphingobacteriia				ko:K08676					ko00000,ko01000,ko01002				Bacteria	1IRKC@117747,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2	NA|NA|NA	M	Tricorn protease homolog
MAG.T21.18_00242	700598.Niako_6871	6e-95	354.4	Sphingobacteriia	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000				Bacteria	1IVXW@117747,4NFG4@976,COG3483@1,COG3483@2	NA|NA|NA	E	Tryptophan 2,3-dioxygenase
MAG.T21.18_00244	1408433.JHXV01000030_gene1415	3.5e-126	459.1	Bacteroidetes				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	4P12F@976,COG3391@1,COG3391@2	NA|NA|NA	E	Zinc metalloprotease (Elastase)
MAG.T21.18_00245	765420.OSCT_0991	1.1e-53	216.9	Chloroflexia	pcaD												Bacteria	2G6VQ@200795,377CS@32061,COG0596@1,COG0596@2	NA|NA|NA	S	PFAM alpha beta hydrolase fold
MAG.T21.18_00247	269800.Tfu_1444	2.9e-27	129.4	Streptosporangiales				ko:K07052					ko00000				Bacteria	2IID1@201174,4EJUP@85012,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
MAG.T21.18_00248	935567.JAES01000028_gene2673	1.5e-17	95.1	Xanthomonadales	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K14761					ko00000,ko03009				Bacteria	1N7NW@1224,1SCJU@1236,1X879@135614,COG2501@1,COG2501@2	NA|NA|NA	S	RNA-binding protein
MAG.T21.18_00249	1123234.AUKI01000004_gene58	1.8e-42	179.1	Flavobacteriia	greA			ko:K03624,ko:K04760					ko00000,ko03021				Bacteria	1I2YK@117743,4NM9C@976,COG0782@1,COG0782@2	NA|NA|NA	K	Transcription elongation factor
MAG.T21.18_00250	743722.Sph21_3286	8e-118	430.3	Sphingobacteriia	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110			iNJ661.Rv3913	Bacteria	1IQ1P@117747,4NEVX@976,COG0492@1,COG0492@2	NA|NA|NA	C	Thioredoxin reductase
MAG.T21.18_00251	1120951.AUBG01000007_gene63	1.2e-33	149.4	Flavobacteriia													Bacteria	1I37T@117743,4NSEK@976,COG2259@1,COG2259@2	NA|NA|NA	S	DoxX family
MAG.T21.18_00252	755732.Fluta_3294	8e-57	227.6	Bacteroidetes													Bacteria	2BG4X@1,33858@2,4NW0E@976	NA|NA|NA	S	Domain of unknown function (DUF4249)
MAG.T21.18_00253	755732.Fluta_3295	4e-230	804.7	Flavobacteriia													Bacteria	1IN1U@117743,4PM6D@976,COG4206@1,COG4206@2	NA|NA|NA	H	CarboxypepD_reg-like domain
MAG.T21.18_00254	1340493.JNIF01000003_gene4830	7.3e-38	164.1	Bacteria				ko:K02282					ko00000,ko02035,ko02044				Bacteria	COG2197@1,COG2197@2	NA|NA|NA	K	response regulator
MAG.T21.18_00255	1121889.AUDM01000003_gene2208	3.6e-132	478.4	Flavobacterium			2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	1HXAI@117743,2NVFA@237,4NFYY@976,COG3550@1,COG3550@2	NA|NA|NA	S	Pfam:HipA_N
MAG.T21.18_00256	269798.CHU_3780	1.5e-16	92.4	Bacteroidetes													Bacteria	4PM2T@976,COG3620@1,COG3620@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.18_00257	935863.AWZR01000006_gene1348	5e-21	107.8	Xanthomonadales													Bacteria	1QVVF@1224,1T2K8@1236,1XDCD@135614,COG2062@1,COG2062@2	NA|NA|NA	T	Phosphoglycerate mutase family
MAG.T21.18_00258	1121286.AUMT01000004_gene844	5.5e-26	124.0	Chryseobacterium													Bacteria	1I196@117743,3ZRRU@59732,4NP44@976,COG0346@1,COG0346@2,COG0454@1,COG0456@2	NA|NA|NA	K	GCN5 family acetyltransferase
MAG.T21.18_00259	1296415.JACC01000001_gene3612	1.2e-38	165.6	Aquimarina				ko:K06147,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1HWRN@117743,2YHZC@290174,4PKCT@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
MAG.T21.18_00260	946077.W5A_01135	3e-170	604.7	Flavobacteriia	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007			iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896	Bacteria	1HY5U@117743,4NFBU@976,COG0156@1,COG0156@2	NA|NA|NA	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
MAG.T21.18_00261	1237149.C900_02118	2.5e-16	93.2	Cytophagia				ko:K07052					ko00000				Bacteria	47SVF@768503,4NVAP@976,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
MAG.T21.18_00262	761193.Runsl_1550	2.8e-10	73.6	Cytophagia													Bacteria	47JT4@768503,4NI5M@976,COG4409@1,COG4409@2	NA|NA|NA	G	BNR repeat-like domain
MAG.T21.18_00263	926556.Echvi_4562	4.8e-38	164.9	Bacteria				ko:K05303					ko00000,ko01000				Bacteria	COG4122@1,COG4122@2	NA|NA|NA	E	O-methyltransferase activity
MAG.T21.18_00264	1123248.KB893359_gene2118	4.4e-22	110.5	Sphingobacteriia	gatC		6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029			iAF987.Gmet_0076	Bacteria	1ITUB@117747,4NV0A@976,COG0721@1,COG0721@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAG.T21.18_00265	1408433.JHXV01000016_gene1862	2.2e-52	212.6	Cryomorphaceae	plsC		2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1HXST@117743,2PB5B@246874,4NG5R@976,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
MAG.T21.18_00266	592029.DDD_1493	9.4e-122	443.4	Nonlabens	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1HY8G@117743,3HJWH@363408,4NETX@976,COG0180@1,COG0180@2	NA|NA|NA	J	tRNA synthetases class I (W and Y)
MAG.T21.18_00267	1124780.ANNU01000061_gene902	1.7e-110	406.4	Cytophagia													Bacteria	47M6X@768503,4NE5U@976,COG1228@1,COG1228@2	NA|NA|NA	Q	PFAM Amidohydrolase family
MAG.T21.18_00268	504472.Slin_1771	2.2e-249	869.0	Cytophagia			3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130		R02059	RC00166,RC00300	ko00000,ko00001,ko01000				Bacteria	47JC0@768503,4NF27@976,COG1228@1,COG1228@2	NA|NA|NA	Q	PFAM amidohydrolase
MAG.T21.18_00269	1237149.C900_05872	4.9e-119	434.9	Cytophagia	arcD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	47MN0@768503,4NEUI@976,COG1288@1,COG1288@2	NA|NA|NA	S	C4-dicarboxylate anaerobic carrier
MAG.T21.18_00270	1166018.FAES_4556	4.7e-20	104.4	Cytophagia													Bacteria	29AZZ@1,2ZXYX@2,47Q19@768503,4NP6M@976	NA|NA|NA		
MAG.T21.18_00271	1121373.KB903620_gene2049	2.7e-12	78.2	Cytophagia				ko:K00406,ko:K12263	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156			ko00000,ko00001,ko00002	3.D.4.3			Bacteria	47R5S@768503,4NSUK@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome C oxidase, cbb3-type, subunit III
MAG.T21.18_00272	742725.HMPREF9450_01021	6e-142	510.8	Rikenellaceae	hflX			ko:K03665					ko00000,ko03009				Bacteria	22U3K@171550,2FM9T@200643,4NF0P@976,COG2262@1,COG2262@2	NA|NA|NA	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAG.T21.18_00273	926562.Oweho_2096	1e-148	533.9	Cryomorphaceae	msbA			ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	1HWWR@117743,2PAGR@246874,4NE2D@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC-type multidrug transport system ATPase and permease
MAG.T21.18_00274	742817.HMPREF9449_02791	4.8e-25	120.6	Porphyromonadaceae	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360		ko:K02834					ko00000,ko03009				Bacteria	22YGP@171551,2FT27@200643,4NSQJ@976,COG0858@1,COG0858@2	NA|NA|NA	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAG.T21.18_00275	1356852.N008_08405	2e-96	359.0	Cytophagia			2.1.1.187,2.1.1.197	ko:K00563,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R07233,R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	47PJZ@768503,4PP98@976,COG0500@1,COG0500@2	NA|NA|NA	Q	Methyltransferase domain
MAG.T21.18_00276	946483.Cenrod_2232	2.3e-170	605.9	Comamonadaceae	mod		2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	1MX9M@1224,2VGZB@28216,4ACWT@80864,COG2189@1,COG2189@2	NA|NA|NA	L	PFAM DNA methylase N-4 N-6 domain protein
MAG.T21.18_00277	491916.RHECIAT_PC0000109	4e-141	508.4	Rhizobiaceae			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1MXG1@1224,2U2ED@28211,4BHP1@82115,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.18_00278	552811.Dehly_1610	0.0	1276.2	Dehalococcoidia	res		3.1.21.5	ko:K01156					ko00000,ko01000,ko02048				Bacteria	2GAYU@200795,34DKW@301297,COG3587@1,COG3587@2	NA|NA|NA	L	Type III restriction enzyme, res subunit
MAG.T21.18_00279	1408473.JHXO01000001_gene1964	3.4e-68	265.8	Bacteroidia	lolE			ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255			ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5			Bacteria	2FNHB@200643,4NG04@976,COG4591@1,COG4591@2	NA|NA|NA	M	Efflux ABC transporter, permease protein
MAG.T21.18_00280	1123276.KB893260_gene2603	8.7e-131	473.4	Cytophagia	dus			ko:K05540					ko00000,ko01000,ko03016				Bacteria	47JGV@768503,4NEN4@976,COG0042@1,COG0042@2	NA|NA|NA	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAG.T21.18_00281	313595.P700755_002454	1.1e-37	162.9	Psychroflexus				ko:K03559					ko00000,ko02000	1.A.30.2.1			Bacteria	1I1CY@117743,4C2K2@83612,4NKT1@976,COG0848@1,COG0848@2	NA|NA|NA	U	Biopolymer transport protein ExbD/TolR
MAG.T21.18_00282	385682.AFSL01000006_gene2382	1.6e-36	159.8	Marinilabiliaceae				ko:K03832					ko00000,ko02000	2.C.1.1			Bacteria	2FMZ4@200643,3XJ4Z@558415,4NHYQ@976,COG0848@1,COG0848@2	NA|NA|NA	U	Biopolymer transport protein ExbD/TolR
MAG.T21.18_00283	1178825.ALIH01000003_gene2022	1.5e-09	69.3	Flavobacteriia													Bacteria	1I3WD@117743,2AT2U@1,31IIU@2,4NS9K@976	NA|NA|NA		
MAG.T21.18_00284	746697.Aeqsu_1444	5.5e-77	294.3	Flavobacteriia	exbB			ko:K03561					ko00000,ko02000	1.A.30.2.1			Bacteria	1HXZK@117743,4NEA2@976,COG0811@1,COG0811@2	NA|NA|NA	U	Mota tolq exbb proton channel
MAG.T21.18_00286	1121098.HMPREF1534_00643	6.9e-99	367.5	Bacteroidaceae	ansA		3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110		R00485	RC00010,RC02798	ko00000,ko00001,ko01000				Bacteria	2FM3E@200643,4ANB4@815,4NE2Z@976,COG0252@1,COG0252@2	NA|NA|NA	EJ	L-asparaginase, type I
MAG.T21.18_00287	1408433.JHXV01000006_gene2660	5.4e-75	287.7	Cryomorphaceae	tatD			ko:K03424					ko00000,ko01000				Bacteria	1HXDX@117743,2PAPA@246874,4NEVW@976,COG0084@1,COG0084@2	NA|NA|NA	L	TatD related DNase
MAG.T21.18_00288	468059.AUHA01000003_gene1426	1.8e-92	346.3	Sphingobacteriia				ko:K02843	ko00540,ko01100,map00540,map01100	M00080			ko00000,ko00001,ko00002,ko01000,ko01003,ko01005		GT9		Bacteria	1INZA@117747,4NEPH@976,COG0859@1,COG0859@2	NA|NA|NA	M	Glycosyl transferase, family 9
MAG.T21.18_00289	1123269.NX02_25940	9.2e-14	83.2	Bacteria													Bacteria	2ERBI@1,33IX6@2	NA|NA|NA		
MAG.T21.18_00290	1453500.AT05_07335	4e-50	204.5	Flavobacteriia	ykhA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	3.1.2.20	ko:K01073					ko00000,ko01000				Bacteria	1HZ1Y@117743,4NERA@976,COG1607@1,COG1607@2	NA|NA|NA	I	thioesterase
MAG.T21.18_00291	1249975.JQLP01000001_gene3130	1e-22	113.6	Gillisia				ko:K08973					ko00000				Bacteria	1HX86@117743,2P5KB@244698,4NEWG@976,COG1981@1,COG1981@2	NA|NA|NA	S	Uncharacterised protein family (UPF0093)
MAG.T21.18_00294	620914.JH621301_gene3553	9.9e-32	144.4	Aquimarina	ftsZ			ko:K01932,ko:K03317,ko:K03531,ko:K03980	ko04112,map04112				ko00000,ko00001,ko01000,ko01011,ko02000,ko02048,ko03036,ko04812	2.A.41,2.A.66.4			Bacteria	1HYQM@117743,2YHD7@290174,4NF9U@976,COG3087@1,COG3087@2	NA|NA|NA	D	Sporulation related domain
MAG.T21.18_00295	1166018.FAES_3907	2.4e-61	242.3	Cytophagia	kdsB		2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	47M2Z@768503,4NG4B@976,COG1212@1,COG1212@2	NA|NA|NA	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MAG.T21.18_00296	1227739.Hsw_0110	5.9e-69	268.9	Cytophagia													Bacteria	47UYH@768503,4NP7Y@976,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAG.T21.18_00297	755732.Fluta_1488	8.6e-151	541.2	Bacteroidetes				ko:K02014,ko:K16092					ko00000,ko02000	1.B.14,1.B.14.3			Bacteria	4NIJS@976,COG4206@1,COG4206@2	NA|NA|NA	H	COG4206 Outer membrane cobalamin receptor protein
MAG.T21.18_00298	1168034.FH5T_11720	1e-95	357.1	Bacteroidia	dprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496		ko:K04096					ko00000				Bacteria	2FKYE@200643,4NF7T@976,COG0758@1,COG0758@2	NA|NA|NA	LU	DNA protecting protein DprA
MAG.T21.18_00299	1380384.JADN01000004_gene2038	1.6e-196	692.2	Flavobacteriia	gdhA		1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100		R00248	RC00006,RC02799	ko00000,ko00001,ko01000				Bacteria	1HY7D@117743,4NEBH@976,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
MAG.T21.18_00300	1408433.JHXV01000018_gene3830	7.3e-58	233.0	Cryomorphaceae			3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	1IJV8@117743,2PBPE@246874,4PMMT@976,COG2706@1,COG2706@2,COG3291@1,COG3291@2,COG3292@1,COG3292@2	NA|NA|NA	GT	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
MAG.T21.18_00301	1408433.JHXV01000008_gene169	2.7e-47	194.9	Cryomorphaceae	yqiW												Bacteria	1I177@117743,28NYH@1,2PAV7@246874,2ZBVN@2,4NMB2@976	NA|NA|NA	S	Disulphide isomerase
MAG.T21.18_00302	1121007.AUML01000055_gene2942	7.5e-147	528.5	Aquimarina													Bacteria	1IKGM@117743,2YHK4@290174,4PP90@976,COG2931@1,COG2931@2,COG4733@1,COG4733@2	NA|NA|NA	Q	Fungalysin metallopeptidase (M36)
MAG.T21.18_00303	1239415.CM001837_gene977	6.2e-160	572.0	Dokdonia													Bacteria	1IJHR@117743,37EJG@326319,4PKYS@976,COG4733@1,COG4733@2	NA|NA|NA	S	Fungalysin/Thermolysin Propeptide Motif
MAG.T21.18_00304	927658.AJUM01000040_gene908	1.4e-51	209.1	Marinilabiliaceae	tadA	GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360	3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5,6.3.4.19	ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K04075,ko:K11991	ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120		R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223	RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634	ko00000,ko00001,ko01000,ko01002,ko01011,ko03016				Bacteria	2FSMJ@200643,3XK0R@558415,4NNJ2@976,COG0590@1,COG0590@2	NA|NA|NA	FJ	MafB19-like deaminase
MAG.T21.18_00305	760192.Halhy_4524	9.2e-95	354.4	Sphingobacteriia	peaA		1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120		R00606	RC00189	ko00000,ko00001,ko01000				Bacteria	1IP2H@117747,4NEEJ@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_00306	929556.Solca_4406	5.4e-168	597.8	Sphingobacteriia	recJ			ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IQ3R@117747,4NDW1@976,COG0608@1,COG0608@2	NA|NA|NA	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ
MAG.T21.18_00309	1121957.ATVL01000006_gene2990	4e-44	184.9	Cytophagia	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100		R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000			iSBO_1134.SBO_0893	Bacteria	47P8Z@768503,4NEEC@976,COG0572@1,COG0572@2	NA|NA|NA	F	Belongs to the uridine kinase family
MAG.T21.18_00310	1492738.FEM21_18030	9.9e-42	176.8	Flavobacterium	nadD		2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1HYH0@117743,2NTGU@237,4NFQI@976,COG1057@1,COG1057@2	NA|NA|NA	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAG.T21.18_00311	927658.AJUM01000044_gene659	4e-56	224.6	Marinilabiliaceae	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8,4.1.1.23	ko:K00942,ko:K01591	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00050,M00051	R00332,R00965,R02090	RC00002,RC00409	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Bacteria	2FNWA@200643,3XJYX@558415,4NEDG@976,COG0194@1,COG0194@2	NA|NA|NA	F	Guanylate kinase homologues.
MAG.T21.18_00312	1211813.CAPH01000005_gene1716	9.1e-68	263.8	Rikenellaceae	yicC			ko:K03316					ko00000	2.A.36			Bacteria	22V1R@171550,2FPBF@200643,4NEU4@976,COG1561@1,COG1561@2	NA|NA|NA	S	Domain of unknown function (DUF1732)
MAG.T21.18_00313	1408433.JHXV01000006_gene2680	1.8e-58	233.0	Cryomorphaceae	MA20_36650												Bacteria	1HYCJ@117743,2PBM7@246874,4NGZ3@976,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
MAG.T21.18_00314	755732.Fluta_1222	9.6e-76	290.8	Cryomorphaceae	mprF			ko:K07027					ko00000,ko02000	4.D.2			Bacteria	1IHMQ@117743,2PBIY@246874,4NIWG@976,COG0392@1,COG0392@2	NA|NA|NA	S	Lysylphosphatidylglycerol synthase TM region
MAG.T21.18_00316	927658.AJUM01000037_gene1909	1.9e-93	349.0	Marinilabiliaceae	hemD		2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000				Bacteria	2FMX9@200643,3XIXK@558415,4NEQ3@976,COG1587@1,COG1587@2	NA|NA|NA	H	Uroporphyrinogen-III synthase HemD
MAG.T21.18_00317	1408473.JHXO01000001_gene2072	1.2e-11	76.3	Bacteroidia	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998					ko00000,ko01000,ko03016				Bacteria	2FUKM@200643,4NUMM@976,COG0594@1,COG0594@2	NA|NA|NA	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAG.T21.18_00318	1406840.Q763_07365	6.7e-24	116.3	Flavobacterium	yidD			ko:K08998					ko00000				Bacteria	1I3W5@117743,2NX2C@237,4NV1N@976,COG0759@1,COG0759@2	NA|NA|NA	S	Could be involved in insertion of integral membrane proteins into the membrane
MAG.T21.18_00319	153721.MYP_2127	6e-148	531.2	Cytophagia	prc		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	47JTG@768503,4NDWU@976,COG0793@1,COG0793@2	NA|NA|NA	M	Belongs to the peptidase S41A family
MAG.T21.18_00320	1168034.FH5T_14375	3.7e-35	156.4	Bacteria				ko:K16705					ko00000				Bacteria	COG3307@1,COG3307@2	NA|NA|NA	M	-O-antigen
MAG.T21.18_00321	1121904.ARBP01000005_gene4622	3.6e-81	308.1	Cytophagia	lgtF			ko:K12984					ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2		Bacteria	47XHY@768503,4NGYU@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.18_00322	1122176.KB903565_gene3321	2.7e-105	390.2	Sphingobacteriia													Bacteria	1ITAS@117747,4NF1M@976,COG1404@1,COG1404@2	NA|NA|NA	O	Serine protease, subtilase family
MAG.T21.18_00323	1227739.Hsw_0324	7.8e-197	694.1	Cytophagia	alr		5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502		R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011				Bacteria	47JKP@768503,4NEXM@976,COG0770@1,COG0770@2,COG0787@1,COG0787@2	NA|NA|NA	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAG.T21.18_00324	742817.HMPREF9449_01584	1.7e-70	272.3	Porphyromonadaceae	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000			iLJ478.TM0401	Bacteria	22W1X@171551,2FN2K@200643,4NE5R@976,COG1435@1,COG1435@2	NA|NA|NA	F	thymidine kinase
MAG.T21.18_00325	1408433.JHXV01000022_gene3171	7.6e-07	61.2	Cryomorphaceae													Bacteria	1ICTM@117743,2A9DD@1,2PC49@246874,30YIJ@2,4PCCR@976	NA|NA|NA		
MAG.T21.18_00326	1279009.ADICEAN_01159	2.2e-86	326.2	Cytophagia													Bacteria	47NIK@768503,4NGPJ@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.18_00327	1121100.JCM6294_1298	2e-78	298.9	Bacteroidaceae	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	2FMU1@200643,4AMSW@815,4NFQM@976,COG0313@1,COG0313@2	NA|NA|NA	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAG.T21.18_00328	641524.ADICYQ_3841	1.1e-69	270.4	Cytophagia	fadB5		1.6.5.5	ko:K00344					ko00000,ko01000				Bacteria	47XCM@768503,4NF0Z@976,COG0604@1,COG0604@2	NA|NA|NA	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase
MAG.T21.18_00330	1408433.JHXV01000004_gene3413	3.5e-09	70.1	Bacteria													Bacteria	COG1520@1,COG1520@2,COG3291@1,COG3291@2	NA|NA|NA	S	amino acid activation for nonribosomal peptide biosynthetic process
MAG.T21.18_00331	1048983.EL17_22795	1e-190	673.7	Cytophagia	nhaS4												Bacteria	47NZK@768503,4NFPE@976,COG0475@1,COG0475@2	NA|NA|NA	P	Sodium/hydrogen exchanger family
MAG.T21.18_00332	929556.Solca_2600	4.3e-110	404.8	Sphingobacteriia	pheB		2.5.1.54,5.4.99.5	ko:K03856,ko:K04092,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQIZ@117747,4NDU4@976,COG1605@1,COG1605@2,COG2876@1,COG2876@2	NA|NA|NA	E	Dahp synthetase i kdsa
MAG.T21.18_00333	1122176.KB903546_gene1027	6.3e-118	432.2	Bacteroidetes			3.4.21.107	ko:K04771,ko:K20276	ko01503,ko02020,ko02024,map01503,map02020,map02024	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	4PKTY@976,COG0265@1,COG0265@2,COG3291@1,COG3291@2	NA|NA|NA	O	ASPIC and UnbV
MAG.T21.18_00335	745411.B3C1_19004	4.1e-16	91.7	unclassified Gammaproteobacteria	thiF	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008270,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_2482,iECDH1ME8569_1439.ECDH1ME8569_3852,iECDH1ME8569_1439.EcDH1_4002,iECIAI39_1322.ECIAI39_4382,iEcDH1_1363.EcDH1_4002	Bacteria	1J5KJ@118884,1MW7H@1224,1RPJ3@1236,COG0476@1,COG0476@2	NA|NA|NA	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family
MAG.T21.18_00336	1090320.KB900605_gene2300	8e-59	234.6	Sphingomonadales	moeA		2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100		R09735	RC03462	ko00000,ko00001,ko01000				Bacteria	1MVD5@1224,2K1RP@204457,2TQRI@28211,COG0303@1,COG0303@2	NA|NA|NA	H	molybdopterin biosynthesis
MAG.T21.18_00337	671143.DAMO_2576	1.1e-24	120.2	unclassified Bacteria	mobA		2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100		R11581		ko00000,ko00001,ko01000				Bacteria	2NPYD@2323,COG0746@1,COG0746@2	NA|NA|NA	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MAG.T21.18_00338	1123234.AUKI01000019_gene543	3e-07	60.8	Bacteria	moaD			ko:K03636	ko04122,map04122				ko00000,ko00001				Bacteria	COG1977@1,COG1977@2	NA|NA|NA	H	Mo-molybdopterin cofactor metabolic process
MAG.T21.18_00339	1347342.BN863_6540	1.8e-43	182.2	Flavobacteriia	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122		R09395	RC02507	ko00000,ko00001,ko01000				Bacteria	1I24D@117743,4NP1X@976,COG0314@1,COG0314@2	NA|NA|NA	H	Molybdopterin converting factor
MAG.T21.18_00340	1313421.JHBV01000014_gene3843	1.9e-95	355.9	Sphingobacteriia	moaC		4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122		R11372	RC03425	ko00000,ko00001,ko01000				Bacteria	1INZV@117747,4NHA0@976,COG0315@1,COG0315@2,COG0521@1,COG0521@2	NA|NA|NA	H	Molybdenum cofactor biosynthesis protein
MAG.T21.18_00341	1396418.BATQ01000101_gene5458	7.3e-43	183.0	Verrucomicrobiae													Bacteria	2IV8V@203494,46UI8@74201,COG3292@1,COG3292@2,COG4585@1,COG4585@2	NA|NA|NA	T	Y_Y_Y domain
MAG.T21.18_00342	1396141.BATP01000002_gene4845	1e-39	170.2	Verrucomicrobiae													Bacteria	2IVME@203494,46TQM@74201,COG2197@1,COG2197@2	NA|NA|NA	KT	helix_turn_helix, Lux Regulon
MAG.T21.18_00343	1120966.AUBU01000026_gene524	1.1e-84	320.9	Cytophagia													Bacteria	47PRM@768503,4NKVR@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_00344	1089547.KB913013_gene4561	1.6e-32	147.1	Bacteroidetes			3.4.21.50	ko:K01337,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000,ko01002				Bacteria	4NPFV@976,COG1404@1,COG1404@2,COG3209@1,COG3209@2,COG3391@1,COG3391@2,COG4935@1,COG4935@2	NA|NA|NA	MO	regulator of chromosome condensation, RCC1
MAG.T21.18_00345	1237149.C900_02937	8.8e-69	268.1	Bacteroidetes													Bacteria	4NKVR@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_00346	1123277.KB893191_gene2898	3.9e-31	142.5	Bacteria													Bacteria	COG0823@1,COG0823@2,COG5492@1,COG5492@2	NA|NA|NA	N	domain, Protein
MAG.T21.18_00347	1122621.ATZA01000035_gene3591	7e-88	330.9	Sphingobacteriia	moaA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122		R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000				Bacteria	1IPUJ@117747,4NFS9@976,COG2896@1,COG2896@2	NA|NA|NA	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MAG.T21.18_00348	1341181.FLJC2902T_15110	5.5e-81	309.3	Flavobacterium													Bacteria	1IKDI@117743,2P0DY@237,4PKPT@976,COG3386@1,COG3386@2	NA|NA|NA	G	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_00349	1038859.AXAU01000002_gene417	3.7e-54	218.0	Bradyrhizobiaceae	tag		3.2.2.20	ko:K01246	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1R9X5@1224,2TUP5@28211,3JR51@41294,COG2818@1,COG2818@2	NA|NA|NA	L	glycosylase i
MAG.T21.18_00350	575540.Isop_3576	1.2e-19	104.0	Planctomycetes													Bacteria	2J0UY@203682,COG2242@1,COG2242@2	NA|NA|NA	H	TIGRFAM methyltransferase FkbM family
MAG.T21.18_00351	1166018.FAES_3608	5.7e-75	287.7	Cytophagia	fdhD	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363		ko:K02379,ko:K18360	ko00360,map00360		R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001				Bacteria	47MUW@768503,4NFJB@976,COG1526@1,COG1526@2	NA|NA|NA	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MAG.T21.18_00352	316067.Geob_2091	2.2e-41	175.6	Desulfuromonadales													Bacteria	1RH46@1224,2WP4H@28221,42TFI@68525,43VWM@69541,COG2320@1,COG2320@2	NA|NA|NA	S	GrpB protein
MAG.T21.18_00353	1123234.AUKI01000002_gene1758	5.2e-18	97.4	Flavobacteriia													Bacteria	1I22W@117743,4NNMS@976,COG2350@1,COG2350@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.18_00359	153721.MYP_3250	3.6e-13	82.0	Bacteroidetes	amyB3												Bacteria	4NY26@976,COG4733@1,COG4733@2	NA|NA|NA	S	SPTR Putative
MAG.T21.18_00360	1168034.FH5T_20995	1.8e-11	76.3	Bacteria													Bacteria	COG0664@1,COG0664@2	NA|NA|NA	T	cyclic nucleotide binding
MAG.T21.18_00362	1454007.JAUG01000057_gene4510	1.1e-13	83.2	Sphingobacteriia													Bacteria	1IZW0@117747,2910N@1,2ZNNA@2,4P97Z@976	NA|NA|NA		
MAG.T21.18_00365	1538644.KO02_16080	4.9e-150	537.7	Sphingobacteriia	dcm		2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	1IR0T@117747,4NG9A@976,COG0270@1,COG0270@2	NA|NA|NA	H	C-5 cytosine-specific DNA methylase
MAG.T21.18_00366	402612.FP0737	2.1e-58	232.3	Bacteria													Bacteria	29UK0@1,30FX9@2	NA|NA|NA	S	Restriction endonuclease BglII
MAG.T21.18_00367	1296416.JACB01000003_gene720	0.0	1229.2	Aquimarina	fdsA		1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000				Bacteria	1IKVD@117743,2YKIF@290174,4PKV4@976,COG3383@1,COG3383@2	NA|NA|NA	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
MAG.T21.18_00369	1122176.KB903598_gene4712	1.6e-88	335.1	Bacteria													Bacteria	COG2866@1,COG2866@2	NA|NA|NA	E	metallocarboxypeptidase activity
MAG.T21.18_00370	1122176.KB903609_gene5170	1.8e-40	174.5	Bacteroidetes													Bacteria	4PNNJ@976,COG1361@1,COG1361@2	NA|NA|NA	M	Conserved repeat domain
MAG.T21.18_00372	1408433.JHXV01000011_gene2011	7e-52	211.1	Cryomorphaceae	motB			ko:K02557	ko02030,ko02040,map02030,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	1HXG8@117743,2PAWA@246874,4NGHP@976,COG1360@1,COG1360@2	NA|NA|NA	N	OmpA family
MAG.T21.18_00373	1124780.ANNU01000023_gene3189	4.8e-29	135.2	Cytophagia													Bacteria	28KKN@1,2ZA5E@2,47PT5@768503,4NMKH@976	NA|NA|NA		
MAG.T21.18_00374	517418.Ctha_2624	7.1e-109	401.4	Bacteria				ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG4166@1,COG4166@2	NA|NA|NA	E	transmembrane transport
MAG.T21.18_00375	755732.Fluta_1812	2.9e-229	802.4	Bacteroidetes													Bacteria	4PKQ9@976,COG3536@1,COG3536@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.18_00376	1408433.JHXV01000020_gene3501	1.6e-30	140.2	Cryomorphaceae				ko:K07484					ko00000				Bacteria	1IKDW@117743,2PBQB@246874,4PKE4@976,COG4372@1,COG4372@2	NA|NA|NA	S	Transposase
MAG.T21.18_00377	760192.Halhy_3954	2.3e-45	189.1	Sphingobacteriia	comF												Bacteria	1IRYV@117747,4NNI1@976,COG1040@1,COG1040@2	NA|NA|NA	S	PFAM Phosphoribosyl transferase domain
MAG.T21.18_00378	763034.HMPREF9446_03827	1.5e-43	182.6	Bacteroidaceae	msrC		1.8.4.14	ko:K08968	ko00270,map00270		R02025	RC00639	ko00000,ko00001,ko01000				Bacteria	2FS26@200643,4AQQT@815,4NM6D@976,COG1956@1,COG1956@2	NA|NA|NA	T	Psort location Cytoplasmic, score 8.96
MAG.T21.18_00379	1296415.JACC01000023_gene4293	1.3e-51	211.1	Aquimarina													Bacteria	1HWU2@117743,2YHUV@290174,4NGPF@976,COG4704@1,COG4704@2	NA|NA|NA	S	Bacterial Ig-like domain
MAG.T21.18_00380	760192.Halhy_5656	6.7e-70	273.5	Sphingobacteriia			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	1IR0W@117747,4NDZC@976,COG2373@1,COG2373@2,COG3291@1,COG3291@2,COG4386@1,COG4386@2,COG4409@1,COG4409@2	NA|NA|NA	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_00381	1168065.DOK_14759	2.4e-75	288.9	unclassified Gammaproteobacteria	yafV		3.5.1.3	ko:K13566	ko00250,map00250		R00269,R00348	RC00010	ko00000,ko00001,ko01000				Bacteria	1J9HW@118884,1MXBR@1224,1RQ4Z@1236,COG0388@1,COG0388@2	NA|NA|NA	S	amidohydrolase
MAG.T21.18_00382	1300345.LF41_905	2.1e-128	465.7	Xanthomonadales	ybdL	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.6.1.17,2.6.1.88	ko:K14267,ko:K14287	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475,R08618	RC00006,RC00025	ko00000,ko00001,ko00002,ko01000,ko01007			iNJ661.Rv0858c	Bacteria	1MW0Z@1224,1RNN0@1236,1X49S@135614,COG0436@1,COG0436@2	NA|NA|NA	E	aminotransferase
MAG.T21.18_00383	926562.Oweho_2664	9.5e-114	416.4	Cryomorphaceae	sdhB		1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2395	Bacteria	1HYVV@117743,2PAAP@246874,4NFR3@976,COG0479@1,COG0479@2	NA|NA|NA	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit
MAG.T21.18_00384	224914.BMEII0522	8.6e-23	113.6	Alphaproteobacteria			2.6.1.102	ko:K13010	ko00520,map00520		R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007				Bacteria	1N0QW@1224,2TX9R@28211,COG0399@1,COG0399@2	NA|NA|NA	M	23S rRNA-intervening sequence protein
MAG.T21.18_00385	926562.Oweho_2662	0.0	1097.4	Cryomorphaceae	sdhA		1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWUS@117743,2PA8P@246874,4NFDU@976,COG1053@1,COG1053@2	NA|NA|NA	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup
MAG.T21.18_00386	471854.Dfer_3969	1.9e-76	292.4	Cytophagia	sdhC			ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002				Bacteria	2CAZH@1,2Z7RU@2,47NEV@768503,4NGM5@976	NA|NA|NA	S	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family
MAG.T21.18_00387	1121895.Q765_10485	2.7e-28	131.7	Flavobacterium													Bacteria	1I6FE@117743,2NWFZ@237,31TV8@2,4NQJ7@976,COG2259@1	NA|NA|NA	S	DoxX-like family
MAG.T21.18_00388	755732.Fluta_1585	2.4e-24	118.6	Flavobacteriia													Bacteria	1I3WE@117743,4NQ5C@976,COG1733@1,COG1733@2	NA|NA|NA	K	HxlR family transcriptional regulator
MAG.T21.18_00389	761193.Runsl_2415	6e-92	344.4	Cytophagia	adhB												Bacteria	47N6X@768503,4NHQV@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_00390	1453505.JASY01000007_gene1036	1e-32	146.4	Flavobacterium													Bacteria	1I4BI@117743,2CHCP@1,2NWBW@237,32S5R@2,4NS9G@976	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_00391	376686.Fjoh_3533	3.9e-37	162.5	Flavobacterium													Bacteria	1IN6T@117743,2E4D5@1,2NY45@237,32Z8J@2,4NV2Y@976	NA|NA|NA		
MAG.T21.18_00392	1250278.JQNQ01000001_gene2147	3.9e-52	211.5	Flavobacteriia	acrD			ko:K18989		M00720			ko00000,ko00002,ko02000	2.A.6.2.30			Bacteria	1HX2H@117743,4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.18_00393	1379698.RBG1_1C00001G0793	4.2e-30	139.8	Bacteria													Bacteria	COG1572@1,COG1572@2	NA|NA|NA	NU	bacterial-type flagellum-dependent cell motility
MAG.T21.18_00395	866536.Belba_0485	9.5e-50	203.8	Cytophagia													Bacteria	47QFV@768503,4NF8A@976,COG3279@1,COG3279@2	NA|NA|NA	T	LytTr DNA-binding domain
MAG.T21.18_00396	1237149.C900_00070	6.4e-47	195.7	Cytophagia	pdtaS		2.7.13.3	ko:K00936		M00839			ko00000,ko00002,ko01000,ko01001,ko02022				Bacteria	47MIH@768503,4NINT@976,COG0457@1,COG0457@2,COG3920@1,COG3920@2	NA|NA|NA	T	HWE histidine kinase
MAG.T21.18_00397	1237149.C900_05697	1.4e-117	429.5	Cytophagia		GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008											Bacteria	47N0Q@768503,4NFCN@976,COG0667@1,COG0667@2	NA|NA|NA	C	PFAM Aldo keto reductase family
MAG.T21.18_00398	1380354.JIAN01000005_gene1967	1.4e-11	77.8	Actinobacteria													Bacteria	2IFM1@201174,COG1225@1,COG1225@2	NA|NA|NA	O	Alkyl hydroperoxide reductase
MAG.T21.18_00399	929703.KE386491_gene2810	8.1e-81	307.0	Cytophagia	lolD			ko:K09810	ko02010,map02010	M00255			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125			Bacteria	47KXC@768503,4NFCG@976,COG1136@1,COG1136@2	NA|NA|NA	V	Part of the ABC transporter complex LolCDE involved in the translocation of
MAG.T21.18_00400	929703.KE386491_gene2811	1.9e-135	489.2	Cytophagia	lolC			ko:K09808	ko02010,map02010	M00255			ko00000,ko00001,ko00002,ko02000	3.A.1.125			Bacteria	47MB4@768503,4NHBR@976,COG4591@1,COG4591@2	NA|NA|NA	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component
MAG.T21.18_00401	468059.AUHA01000006_gene2995	6.2e-74	284.6	Sphingobacteriia				ko:K02005					ko00000				Bacteria	1ISHH@117747,4NITE@976,COG0845@1,COG0845@2	NA|NA|NA	M	SPTR Efflux transporter, RND family, MFP subunit
MAG.T21.18_00402	1296415.JACC01000001_gene3507	3.9e-53	215.7	Aquimarina	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1I0KW@117743,2YJ8Q@290174,4NI7H@976,COG3146@1,COG3146@2	NA|NA|NA	S	8-amino-7-oxononanoate synthase
MAG.T21.18_00403	216432.CA2559_04870	8.3e-85	320.9	Flavobacteriia	XCC0762			ko:K07038					ko00000				Bacteria	1HY38@117743,4NFBT@976,COG1988@1,COG1988@2	NA|NA|NA	S	membrane-bound metal-dependent
MAG.T21.18_00404	1469557.JSWF01000028_gene2970	6.8e-34	150.6	Flavobacteriia													Bacteria	1I2ET@117743,29E7I@1,3015I@2,4NNFG@976	NA|NA|NA	S	Protein of unknown function (DUF1761)
MAG.T21.18_00405	1296415.JACC01000001_gene3510	1.2e-29	136.7	Aquimarina													Bacteria	1I8SB@117743,2YJT5@290174,4NH3F@976,COG1280@1,COG1280@2	NA|NA|NA	E	LysE type translocator
MAG.T21.18_00406	1297742.A176_03275	2.4e-58	231.5	Proteobacteria	amnD		3.5.99.5,4.1.1.77	ko:K01617,ko:K15067	ko00362,ko00380,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00621,map00622,map01100,map01120,map01220	M00569	R02602,R03887,R05374	RC00751,RC01015,RC02672	ko00000,ko00001,ko00002,ko01000				Bacteria	1MYEM@1224,COG0251@1,COG0251@2	NA|NA|NA	J	Translation initiation inhibitor, yjgF family
MAG.T21.18_00407	1410608.JNKX01000042_gene1161	7.9e-70	271.2	Bacteroidaceae				ko:K07148					ko00000				Bacteria	2FP63@200643,4AN9T@815,4NG01@976,COG2311@1,COG2311@2	NA|NA|NA	S	Protein of unknown function (DUF418)
MAG.T21.18_00408	1210045.ALNP01000013_gene1355	2.8e-93	349.4	Actinobacteria	sdcS			ko:K14445					ko00000,ko02000	2.A.47.1			Bacteria	2GVHZ@201174,COG0471@1,COG0471@2	NA|NA|NA	P	transporter
MAG.T21.18_00409	1122176.KB903546_gene1038	2.7e-21	108.2	Sphingobacteriia													Bacteria	1IUJT@117747,2DZQQ@1,32VGE@2,4NTQG@976	NA|NA|NA	S	Transmembrane family 220, helix
MAG.T21.18_00410	1434325.AZQN01000007_gene3154	4.8e-132	478.8	Cytophagia													Bacteria	47K3W@768503,4PKVH@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.18_00411	153721.MYP_2754	5.3e-07	62.0	Bacteroidetes													Bacteria	28PY8@1,2ZCHZ@2,4NMGG@976	NA|NA|NA		
MAG.T21.18_00412	1122605.KB893627_gene3022	5.4e-68	264.6	Sphingobacteriia	yniA	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237											Bacteria	1IRXQ@117747,4NEQY@976,COG3001@1,COG3001@2	NA|NA|NA	G	PFAM fructosamine kinase
MAG.T21.18_00415	1408473.JHXO01000010_gene3689	1.2e-286	993.0	Bacteroidia			3.1.3.16	ko:K06382					ko00000,ko01000				Bacteria	2G0DB@200643,4NZYS@976,COG0038@1,COG0038@2	NA|NA|NA	P	Protein of unknown function (DUF2723)
MAG.T21.18_00416	926562.Oweho_2739	3.2e-54	218.4	Cryomorphaceae	pgdA_1												Bacteria	1I1F1@117743,2PAZ8@246874,4NM7D@976,COG0726@1,COG0726@2	NA|NA|NA	G	Polysaccharide deacetylase
MAG.T21.18_00417	643867.Ftrac_1237	1.2e-103	384.4	Cytophagia				ko:K03640					ko00000,ko02000	2.C.1.2			Bacteria	47K1N@768503,4NE6G@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein
MAG.T21.18_00418	485918.Cpin_3624	5.5e-71	274.6	Sphingobacteriia													Bacteria	1IP9M@117747,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_00419	143224.JQMD01000002_gene4209	3.9e-211	743.4	Flavobacteriia	rtxA		3.2.1.4	ko:K01179,ko:K13735	ko00500,ko01100,ko05100,map00500,map01100,map05100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	1HXFW@117743,4NG93@976,COG1361@1,COG1361@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2,COG4932@1,COG4932@2	NA|NA|NA	M	regulator of chromosome condensation, RCC1
MAG.T21.18_00420	1408433.JHXV01000015_gene1745	6.2e-59	234.6	Bacteria													Bacteria	COG3064@1,COG3064@2	NA|NA|NA	M	translation initiation factor activity
MAG.T21.18_00421	1408433.JHXV01000015_gene1746	0.0	1335.9	Cryomorphaceae													Bacteria	1HY1V@117743,2PBEH@246874,4NDZC@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2	NA|NA|NA	M	SPTR CHU large protein
MAG.T21.18_00422	1408433.JHXV01000015_gene1747	1.2e-44	187.2	Cryomorphaceae													Bacteria	1INKQ@117743,2PBQE@246874,4NM6Q@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_00423	755732.Fluta_0919	6.3e-41	174.9	Bacteria													Bacteria	COG3405@1,COG3405@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MAG.T21.18_00424	1089547.KB913013_gene4561	2.2e-29	137.5	Bacteroidetes			3.4.21.50	ko:K01337,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000,ko01002				Bacteria	4NPFV@976,COG1404@1,COG1404@2,COG3209@1,COG3209@2,COG3391@1,COG3391@2,COG4935@1,COG4935@2	NA|NA|NA	MO	regulator of chromosome condensation, RCC1
MAG.T21.18_00426	927658.AJUM01000024_gene2558	4.3e-21	109.0	Marinilabiliaceae													Bacteria	2FTKQ@200643,3XJ0G@558415,4NGW4@976,COG4935@1,COG4935@2	NA|NA|NA	O	Peptide-N-glycosidase F, C terminal
MAG.T21.18_00428	1237149.C900_04830	5.2e-132	477.2	Cytophagia	menB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000				Bacteria	47JYS@768503,4NDXT@976,COG0447@1,COG0447@2	NA|NA|NA	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MAG.T21.18_00431	266762.HQ36_07950	1.1e-71	276.9	Porphyromonadaceae	czcD			ko:K16264					ko00000,ko02000	2.A.4.1			Bacteria	22W19@171551,2FNQ7@200643,4NIHB@976,COG1230@1,COG1230@2	NA|NA|NA	P	Transporter
MAG.T21.18_00434	1121897.AUGO01000004_gene997	8.4e-54	217.2	Flavobacterium													Bacteria	1I3FD@117743,2P0EI@237,4NNHE@976,COG3279@1,COG3279@2	NA|NA|NA	T	LytTR family two component system response regulatory protein
MAG.T21.18_00435	143224.JQMD01000002_gene2008	8.3e-50	204.9	Flavobacteriia													Bacteria	1HXAW@117743,4NF45@976,COG0457@1,COG0457@2,COG2972@1,COG2972@2	NA|NA|NA	T	PFAM Signal transduction histidine kinase, internal region
MAG.T21.18_00436	1392490.JHZX01000001_gene869	8.5e-57	228.8	Flavobacteriia			3.4.21.72	ko:K01347					ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1HXFW@117743,4NG93@976,COG1361@1,COG1361@2,COG4886@1,COG4886@2,COG4932@1,COG4932@2	NA|NA|NA	M	regulator of chromosome condensation, RCC1
MAG.T21.18_00439	694427.Palpr_1196	2e-35	156.4	Bacteroidetes													Bacteria	2EBPI@1,335PM@2,4NY9J@976	NA|NA|NA		
MAG.T21.18_00440	1120951.AUBG01000016_gene3562	5.6e-16	93.2	Bacteroidetes													Bacteria	4NN57@976,COG2706@1,COG2706@2,COG4412@1,COG4412@2	NA|NA|NA	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
MAG.T21.18_00441	1122621.ATZA01000008_gene936	3.9e-148	531.9	Sphingobacteriia	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576		ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1IR9Y@117747,4NENT@976,COG0358@1,COG0358@2	NA|NA|NA	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAG.T21.18_00443	1089547.KB913013_gene4379	3e-104	385.2	Cytophagia	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110		R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006			iYL1228.KPN_03597,ic_1306.c3945	Bacteria	47KFN@768503,4NET2@976,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
MAG.T21.18_00445	1124780.ANNU01000017_gene1937	1.9e-112	412.5	Cytophagia	rlmN		2.1.1.192	ko:K06941					ko00000,ko01000,ko03009				Bacteria	47KHN@768503,4NFH5@976,COG0820@1,COG0820@2	NA|NA|NA	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MAG.T21.18_00446	1254432.SCE1572_01455	1.5e-25	123.6	Myxococcales				ko:K14274	ko00040,map00040		R02427	RC00713	ko00000,ko00001,ko01000				Bacteria	1R0BF@1224,2X818@28221,2Z21M@29,43CTQ@68525,COG3386@1,COG3386@2	NA|NA|NA	G	Disaggregatase related repeat
MAG.T21.18_00447	1123008.KB905693_gene1474	1.9e-57	229.2	Porphyromonadaceae	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000				Bacteria	22XSS@171551,2FM5H@200643,4NMB5@976,COG1211@1,COG1211@2	NA|NA|NA	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MAG.T21.18_00448	755732.Fluta_0923	1.5e-154	552.4	Cryomorphaceae	queA		2.4.99.17	ko:K07568					ko00000,ko01000,ko03016				Bacteria	1HYMK@117743,2PA7J@246874,4NF2T@976,COG0809@1,COG0809@2	NA|NA|NA	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MAG.T21.18_00449	641143.HMPREF9331_00187	4.3e-53	214.9	Capnocytophaga	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177					ko00000,ko01000,ko03016				Bacteria	1EQN6@1016,1HXCG@117743,4NESK@976,COG0130@1,COG0130@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAG.T21.18_00450	929556.Solca_2954	2.5e-88	332.0	Sphingobacteriia	uppP	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944	3.6.1.27	ko:K06153	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011			iYL1228.KPN_03461	Bacteria	1IPDJ@117747,4NGIZ@976,COG1968@1,COG1968@2	NA|NA|NA	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MAG.T21.18_00451	1211813.CAPH01000013_gene568	8.1e-17	92.8	Bacteroidia	fjo13												Bacteria	2E6VD@1,2FTVZ@200643,331EZ@2,4NUSW@976	NA|NA|NA	S	Psort location CytoplasmicMembrane, score 9.82
MAG.T21.18_00452	468059.AUHA01000002_gene169	2.9e-45	189.1	Sphingobacteriia	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1INNN@117747,4NH05@976,COG2177@1,COG2177@2	NA|NA|NA	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
MAG.T21.18_00453	1313301.AUGC01000006_gene44	0.0	1177.2	Bacteroidetes	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	4NE5K@976,COG0495@1,COG0495@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
MAG.T21.18_00454	1408433.JHXV01000006_gene2725	1.3e-76	293.1	Cryomorphaceae													Bacteria	1HXT1@117743,2PAQC@246874,4NF47@976,COG3170@1,COG3170@2	NA|NA|NA	NU	Protein of unknown function (DUF3108)
MAG.T21.18_00455	1124780.ANNU01000016_gene1825	1.8e-88	333.2	Cytophagia	yebA												Bacteria	47MV0@768503,4NECF@976,COG0739@1,COG0739@2	NA|NA|NA	M	PFAM Peptidase family M23
MAG.T21.18_00456	1237149.C900_03337	1.6e-20	106.3	Cytophagia													Bacteria	295IV@1,2ZSWC@2,47W1I@768503,4NVMA@976	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
MAG.T21.18_00457	643867.Ftrac_3100	2.1e-29	134.8	Cytophagia	MA20_05735												Bacteria	47V9T@768503,4PKFS@976,COG1846@1,COG1846@2	NA|NA|NA	K	Winged helix DNA-binding domain
MAG.T21.18_00458	1185876.BN8_01289	1.6e-27	129.4	Cytophagia													Bacteria	47V8X@768503,4NTQ5@976,COG5395@1,COG5395@2	NA|NA|NA	S	Predicted membrane protein (DUF2306)
MAG.T21.18_00460	491205.JARQ01000004_gene2495	3.4e-45	188.3	Flavobacteriia	cpcT	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017006,GO:0017007,GO:0017009,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564		ko:K05383	ko00196,ko01100,map00196,map01100				ko00000,ko00001,ko00194				Bacteria	1I3KA@117743,2CCNY@1,2Z877@2,4NR3D@976	NA|NA|NA	E	CpeT/CpcT family (DUF1001)
MAG.T21.18_00461	643867.Ftrac_0021	1.9e-254	885.2	Cytophagia	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000			iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037	Bacteria	47KGW@768503,4NE63@976,COG0821@1,COG0821@2	NA|NA|NA	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MAG.T21.18_00462	760192.Halhy_2081	1.6e-26	126.3	Bacteroidetes													Bacteria	28JKT@1,2Z9DG@2,4NJJK@976	NA|NA|NA	S	Protein of unknown function (DUF4230)
MAG.T21.18_00463	1392498.JQLH01000001_gene1369	1.2e-52	213.8	Maribacter													Bacteria	1HXCW@117743,2PGBY@252356,4NE8D@976,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
MAG.T21.18_00464	517418.Ctha_1859	1.6e-174	620.2	Chlorobi	ppk		2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1FEEH@1090,COG0855@1,COG0855@2	NA|NA|NA	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MAG.T21.18_00465	1237149.C900_00377	2.1e-50	206.1	Cytophagia				ko:K09933					ko00000,ko01002				Bacteria	47QA7@768503,4NMII@976,COG3228@1,COG3228@2	NA|NA|NA	S	Glucose-regulated metallo-peptidase M90
MAG.T21.18_00466	1089547.KB913013_gene4397	2.2e-55	221.9	Cytophagia	guaD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.12,3.5.4.3,3.5.4.33	ko:K01487,ko:K01493,ko:K11991	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00429	R01663,R01676,R10223	RC00074,RC00204,RC00477	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016				Bacteria	47PPK@768503,4NNMU@976,COG0590@1,COG0590@2	NA|NA|NA	FJ	MafB19-like deaminase
MAG.T21.18_00467	929556.Solca_3515	1.4e-237	828.9	Sphingobacteriia	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iJN678.aspS,iSFV_1184.SFV_1868	Bacteria	1IR7B@117747,4NECY@976,COG0173@1,COG0173@2	NA|NA|NA	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAG.T21.18_00469	391596.PBAL39_01237	6.2e-88	330.9	Sphingobacteriia													Bacteria	1IR78@117747,4NFJ5@976,COG2326@1,COG2326@2	NA|NA|NA	S	Polyphosphate nucleotide phosphotransferase, PPK2 family
MAG.T21.18_00470	1279009.ADICEAN_02849	3.2e-79	302.0	Cytophagia				ko:K03442,ko:K22044					ko00000,ko02000	1.A.23.2,1.A.23.3			Bacteria	47KC1@768503,4NFMR@976,COG3264@1,COG3264@2	NA|NA|NA	M	Mechanosensitive ion channel
MAG.T21.18_00471	1239962.C943_00154	1.8e-55	221.9	Cytophagia													Bacteria	2AKGE@1,31B89@2,47UY0@768503,4NQ22@976	NA|NA|NA		
MAG.T21.18_00472	1313421.JHBV01000043_gene3072	2.8e-173	614.8	Sphingobacteriia	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IPBI@117747,4NFI7@976,COG3185@1,COG3185@2	NA|NA|NA	E	4-hydroxyphenylpyruvate dioxygenase
MAG.T21.18_00473	1492737.FEM08_36390	1.3e-28	132.9	Flavobacterium													Bacteria	1I3YN@117743,2CCSR@1,2NWJ9@237,32RWC@2,4NSDM@976	NA|NA|NA	S	23S rRNA-intervening sequence protein
MAG.T21.18_00474	1286632.P278_24780	1.8e-183	648.7	Flavobacteriia	hmgA		1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYHK@117743,4NEYZ@976,COG3508@1,COG3508@2	NA|NA|NA	Q	homogentisate 12-dioxygenase
MAG.T21.18_00475	926562.Oweho_2008	1.4e-90	340.1	Cryomorphaceae	yceA			ko:K07146					ko00000				Bacteria	1HX4Z@117743,2PADC@246874,4NEG6@976,COG1054@1,COG1054@2	NA|NA|NA	S	Rhodanase C-terminal
MAG.T21.18_00476	1341181.FLJC2902T_11280	6.4e-115	420.6	Flavobacterium	ltd		4.2.1.45	ko:K01709	ko00520,map00520		R02426	RC00402	ko00000,ko00001,ko01000				Bacteria	1HWX0@117743,2NT4H@237,4NE3U@976,COG0451@1,COG0451@2	NA|NA|NA	GM	NAD-dependent epimerase
MAG.T21.18_00477	755732.Fluta_1974	3.8e-13	82.4	Cryomorphaceae													Bacteria	1IMR5@117743,2PBMX@246874,4PG65@976,COG2849@1,COG2849@2	NA|NA|NA	S	MORN repeat variant
MAG.T21.18_00478	1123008.KB905696_gene2890	2.7e-176	625.2	Porphyromonadaceae	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	Bacteria	22WDE@171551,2FM9D@200643,4NE3Y@976,COG0215@1,COG0215@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
MAG.T21.18_00479	449673.BACSTE_02095	2.8e-84	318.9	Bacteroidaceae	ywaD												Bacteria	2FN1C@200643,4AKTJ@815,4NG2A@976,COG2234@1,COG2234@2	NA|NA|NA	S	glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
MAG.T21.18_00480	216432.CA2559_00200	6.3e-189	667.5	Flavobacteriia													Bacteria	1IJEU@117743,4PKTY@976,COG3291@1,COG3291@2	NA|NA|NA	O	ASPIC and UnbV
MAG.T21.18_00481	1341181.FLJC2902T_23420	1.4e-100	373.2	Flavobacterium													Bacteria	1IJZB@117743,2NU2Y@237,4PMQB@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_00482	1168034.FH5T_03525	9.3e-30	138.3	Bacteroidetes	tuaE			ko:K16705					ko00000				Bacteria	4NMYT@976,COG3307@1,COG3307@2	NA|NA|NA	M	O-Antigen ligase
MAG.T21.18_00484	755732.Fluta_1208	4.1e-306	1057.4	Cryomorphaceae	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440		R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1HXMT@117743,2PA9I@246874,4NDVA@976,COG0258@1,COG0258@2,COG0749@1,COG0749@2	NA|NA|NA	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAG.T21.18_00485	1168289.AJKI01000025_gene1466	1.2e-43	183.7	Marinilabiliaceae													Bacteria	29N3N@1,2G223@200643,32D2M@2,3XJ24@558415,4NRTM@976	NA|NA|NA		
MAG.T21.18_00486	927658.AJUM01000047_gene2832	8.8e-11	73.6	Marinilabiliaceae													Bacteria	2DXS6@1,2G27E@200643,34692@2,3XK8F@558415,4P5EX@976	NA|NA|NA		
MAG.T21.18_00487	641526.ADIWIN_1311	2.1e-20	105.5	Flavobacteriia													Bacteria	1I5TY@117743,2CKRR@1,32SCX@2,4NSV3@976	NA|NA|NA		
MAG.T21.18_00488	1408433.JHXV01000016_gene1824	8.9e-130	471.1	Cryomorphaceae													Bacteria	1I16K@117743,2PC6D@246874,4NJK3@976,COG3291@1,COG3291@2	NA|NA|NA	S	Pregnancy-associated plasma protein-A
MAG.T21.18_00489	755732.Fluta_1217	2.5e-132	479.6	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1HZ7Y@117743,2PBDM@246874,4NGRJ@976,COG3291@1,COG3291@2	NA|NA|NA	O	PFAM Pregnancy-associated plasma protein-A
MAG.T21.18_00490	755732.Fluta_1951	1.5e-121	443.7	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1I16K@117743,2PC6D@246874,4NJK3@976,COG3291@1,COG3291@2	NA|NA|NA	S	Pregnancy-associated plasma protein-A
MAG.T21.18_00491	926549.KI421517_gene39	2.5e-174	618.2	Cytophagia	metC		2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	47JY2@768503,4NF0Q@976,COG0626@1,COG0626@2	NA|NA|NA	E	PFAM Cys Met metabolism PLP-dependent enzyme
MAG.T21.18_00492	1008457.BAEX01000006_gene892	4.7e-179	634.0	Myroides	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYD3@117743,47HX2@76831,4NEKJ@976,COG1960@1,COG1960@2	NA|NA|NA	I	Acyl-CoA dehydrogenase, C-terminal domain
MAG.T21.18_00494	1121930.AQXG01000007_gene413	4.1e-33	148.3	Sphingobacteriia													Bacteria	1IY32@117747,4NQNY@976,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
MAG.T21.18_00496	1453498.LG45_04760	2.3e-158	565.5	Flavobacterium	radA			ko:K04485					ko00000,ko03400				Bacteria	1HY3T@117743,2NT19@237,4NEYA@976,COG1066@1,COG1066@2	NA|NA|NA	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAG.T21.18_00497	207559.Dde_3605	3.4e-43	181.4	Desulfovibrionales	aut		2.7.1.167,2.7.7.70	ko:K03272,ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1REW3@1224,2MBFN@213115,2WPTP@28221,42SGQ@68525,COG0615@1,COG0615@2	NA|NA|NA	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MAG.T21.18_00498	1408433.JHXV01000001_gene715	1.4e-72	280.0	Cryomorphaceae				ko:K07027					ko00000,ko02000	4.D.2			Bacteria	1HXYD@117743,2PB24@246874,4NGPD@976,COG0392@1,COG0392@2	NA|NA|NA	S	Lysylphosphatidylglycerol synthase TM region
MAG.T21.18_00499	1211813.CAPH01000018_gene941	1.9e-40	171.8	Rikenellaceae	panD		4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	22UGY@171550,2FSH0@200643,4NQ42@976,COG0853@1,COG0853@2	NA|NA|NA	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MAG.T21.18_00500	1501391.LG35_01240	9.8e-62	243.8	Rikenellaceae	panC	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25,6.3.2.1	ko:K01918,ko:K13799	ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110	M00052,M00119	R00158,R00512,R01665,R02473	RC00002,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000				Bacteria	22U3M@171550,2FN90@200643,4NFT9@976,COG0414@1,COG0414@2	NA|NA|NA	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MAG.T21.18_00501	869213.JCM21142_52114	1.5e-75	289.7	Cytophagia	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003		GT5		Bacteria	47KUD@768503,4NFP8@976,COG0297@1,COG0297@2	NA|NA|NA	G	PFAM Starch synthase catalytic domain
MAG.T21.18_00502	1408433.JHXV01000006_gene2697	1.3e-33	151.0	Cryomorphaceae													Bacteria	1IFW7@117743,2A79G@1,2PB8Y@246874,30W62@2,4P9IB@976	NA|NA|NA	S	Domain of unknown function (DUF4270)
MAG.T21.18_00503	755732.Fluta_0895	3.1e-259	901.0	Cryomorphaceae	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iAF987.Gmet_1487	Bacteria	1HX0U@117743,2PAC8@246874,4NE8Q@976,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAG.T21.18_00505	1121899.Q764_01990	1.1e-88	332.8	Flavobacterium	sodA		1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016				ko00000,ko00001,ko01000				Bacteria	1HX6F@117743,2NTCR@237,4NDZ4@976,COG0605@1,COG0605@2	NA|NA|NA	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MAG.T21.18_00507	1279009.ADICEAN_00617	5.8e-124	451.4	Cytophagia	ctp		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	47JP7@768503,4NEGV@976,COG0793@1,COG0793@2	NA|NA|NA	M	Belongs to the peptidase S41A family
MAG.T21.18_00508	555500.I215_00525	3.4e-50	204.5	Flavobacteriia	comEB		3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044				Bacteria	1I1AE@117743,4NM48@976,COG2131@1,COG2131@2	NA|NA|NA	F	deaminase
MAG.T21.18_00510	1356852.N008_06950	6.8e-29	135.2	Cytophagia													Bacteria	47R1H@768503,4NH7M@976,COG1566@1,COG1566@2	NA|NA|NA	V	Protein of unknown function (DUF3667)
MAG.T21.18_00511	755732.Fluta_1356	1.1e-111	410.6	Cryomorphaceae													Bacteria	1HXD0@117743,2PAUW@246874,4NE4D@976,COG3975@1,COG3975@2	NA|NA|NA	S	protease with the C-terminal PDZ domain
MAG.T21.18_00512	1349822.NSB1T_10170	2.3e-51	208.4	Porphyromonadaceae	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iSB619.SA_RS07880	Bacteria	22WCA@171551,2FMM2@200643,4NE1C@976,COG0423@1,COG0423@2	NA|NA|NA	J	Catalyzes the attachment of glycine to tRNA(Gly)
MAG.T21.18_00513	929703.KE386491_gene1612	7.9e-304	1049.7	Cytophagia	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	47K9H@768503,4NFA0@976,COG0587@1,COG0587@2	NA|NA|NA	L	DNA-directed DNA polymerase
MAG.T21.18_00514	714943.Mucpa_1621	8.9e-45	186.0	Sphingobacteriia	trxA			ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1ISZS@117747,4NQ5B@976,COG3118@1,COG3118@2	NA|NA|NA	O	Belongs to the thioredoxin family
MAG.T21.18_00515	929556.Solca_0526	4e-90	338.2	Sphingobacteriia													Bacteria	1IRJS@117747,4NG0C@976,COG1721@1,COG1721@2	NA|NA|NA	S	protein (some members contain a von Willebrand factor type A (vWA) domain)
MAG.T21.18_00517	755732.Fluta_3541	9.5e-55	221.1	Bacteroidetes													Bacteria	2BH02@1,32B06@2,4P6DW@976	NA|NA|NA		
MAG.T21.18_00518	929556.Solca_2902	1.6e-46	192.6	Sphingobacteriia													Bacteria	1ISGU@117747,4NQPD@976,COG1510@1,COG1510@2	NA|NA|NA	K	Belongs to the GbsR family
MAG.T21.18_00519	1157708.KB907456_gene2218	3.4e-44	185.7	Comamonadaceae			2.1.1.41	ko:K00559	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00102	R04427,R07481	RC00003,RC01154	ko00000,ko00001,ko00002,ko01000				Bacteria	1Q8SR@1224,2VZQ6@28216,4AGJP@80864,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase domain
MAG.T21.18_00520	1317122.ATO12_20920	2.7e-11	75.1	Flavobacteriia													Bacteria	1I56R@117743,2DN6W@1,32Z3V@2,4NV6A@976	NA|NA|NA		
MAG.T21.18_00521	319236.JCM19294_2200	1.4e-34	152.5	Flavobacteriia													Bacteria	1I4N4@117743,2DN31@1,32V8P@2,4NT9U@976	NA|NA|NA		
MAG.T21.18_00522	926562.Oweho_3327	1.2e-101	376.7	Flavobacteriia	VVA1500			ko:K02005					ko00000				Bacteria	1HXN4@117743,4NFT4@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.18_00523	1121931.AUHG01000010_gene851	5.3e-101	374.8	Flavobacteriia	VP1997			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1HZ09@117743,4NFUG@976,COG0577@1,COG0577@2	NA|NA|NA	V	ABC-type antimicrobial peptide transport system, permease component
MAG.T21.18_00524	502025.Hoch_3520	3.3e-95	355.5	Myxococcales	VP1997			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1PBKH@1224,2WJEU@28221,2YWC8@29,42MAR@68525,COG0577@1,COG0577@2	NA|NA|NA	V	MacB-like periplasmic core domain
MAG.T21.18_00525	203275.BFO_0464	1.2e-81	309.7	Porphyromonadaceae				ko:K02003,ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	22VW5@171551,2FNRG@200643,4NE5N@976,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
MAG.T21.18_00526	760192.Halhy_3247	4.4e-86	325.5	Sphingobacteriia			3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000				Bacteria	1INWP@117747,4NFUI@976,COG1680@1,COG1680@2	NA|NA|NA	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein
MAG.T21.18_00527	1408433.JHXV01000002_gene334	4.3e-33	149.4	Bacteria													Bacteria	COG2374@1,COG2374@2,COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_00529	96561.Dole_3112	2.9e-49	203.0	Deltaproteobacteria													Bacteria	1RGAH@1224,2DM58@1,2WWXE@28221,31S4C@2,431QP@68525	NA|NA|NA		
MAG.T21.18_00530	1122176.KB903619_gene5336	4.3e-44	184.9	Sphingobacteriia	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761					ko00000,ko01000,ko03009				Bacteria	1INQF@117747,4NE2S@976,COG1385@1,COG1385@2	NA|NA|NA	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MAG.T21.18_00531	760192.Halhy_0269	1.3e-79	302.8	Sphingobacteriia													Bacteria	1IQFD@117747,4NFMT@976,COG1657@1,COG1657@2	NA|NA|NA	I	Domain of unknown function (DUF4159)
MAG.T21.18_00532	1123277.KB893244_gene5143	1.4e-13	83.2	Cytophagia													Bacteria	2F2YC@1,33VTR@2,47V6C@768503,4P3SB@976	NA|NA|NA		
MAG.T21.18_00533	1313301.AUGC01000005_gene273	2.4e-134	485.3	Bacteroidetes	kdnB	GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.1.1.1,1.1.3.48	ko:K13954,ko:K19714	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R04880,R05233,R05234,R06917,R06927,R11394	RC00050,RC00088,RC00099,RC00116,RC00649,RC03427	ko00000,ko00001,ko01000,ko01005				Bacteria	4PKHV@976,COG1454@1,COG1454@2	NA|NA|NA	C	alcohol dehydrogenase
MAG.T21.18_00534	1008457.BAEX01000054_gene637	1.2e-128	466.1	Myroides	sucD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071973,GO:0097588,GO:1901564,GO:1902494	6.2.1.5	ko:K01902,ko:K02381	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_0608	Bacteria	1HX04@117743,47HI8@76831,4NE6B@976,COG0074@1,COG0074@2	NA|NA|NA	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MAG.T21.18_00535	926562.Oweho_0419	8.3e-70	271.2	Cryomorphaceae				ko:K08151,ko:K08153		M00668,M00717			ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8			Bacteria	1HYPP@117743,2PAJK@246874,4NFM7@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	PFAM Major Facilitator Superfamily
MAG.T21.18_00536	742743.HMPREF9453_01206	2.5e-48	199.1	Negativicutes	dpnC		3.1.21.4	ko:K01155					ko00000,ko01000,ko02048				Bacteria	1VPX7@1239,28IMK@1,2Z8N2@2,4H719@909932	NA|NA|NA	L	Dam-replacing family
MAG.T21.18_00538	1223410.KN050846_gene869	2.7e-111	409.1	Flavobacteriia	ndh		1.6.99.3	ko:K03885	ko00190,map00190				ko00000,ko00001,ko01000				Bacteria	1HXM8@117743,4NE0H@976,COG1252@1,COG1252@2	NA|NA|NA	C	NADH dehydrogenase
MAG.T21.18_00539	1122226.AUHX01000012_gene1213	1.8e-115	422.9	Flavobacteriia	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K03650			R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016				Bacteria	1HWWM@117743,4NECT@976,COG0486@1,COG0486@2	NA|NA|NA	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAG.T21.18_00540	521719.ATXQ01000001_gene720	3.5e-08	64.7	Bacteria				ko:K03569					ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1			Bacteria	COG1077@1,COG1077@2	NA|NA|NA	D	Cell shape determining protein MreB Mrl
MAG.T21.18_00541	694427.Palpr_2276	4.6e-83	315.1	Porphyromonadaceae	cyoE			ko:K06921					ko00000				Bacteria	22WF5@171551,2FM92@200643,4NGM3@976,COG1672@1,COG1672@2	NA|NA|NA	S	Pfam:Arch_ATPase
MAG.T21.18_00544	1094466.KQS_11045	5.9e-76	292.0	Flavobacterium													Bacteria	1IDGB@117743,2ABJQ@1,2NYC4@237,31114@2,4PFPZ@976	NA|NA|NA	S	PQQ-like domain
MAG.T21.18_00545	1041826.FCOL_02735	1.3e-56	226.9	Flavobacterium													Bacteria	1HZWV@117743,28IS5@1,2NSQ2@237,2Z8RB@2,4NIIH@976	NA|NA|NA		
MAG.T21.18_00546	880074.BARVI_07555	9.7e-32	143.7	Porphyromonadaceae													Bacteria	22XN5@171551,2FNPU@200643,4NM5H@976,COG0224@1,COG0224@2	NA|NA|NA	C	WbqC-like protein
MAG.T21.18_00547	553178.CAPGI0001_0655	7.7e-16	90.5	Capnocytophaga													Bacteria	1ES7Q@1016,1I6FZ@117743,2ETCB@1,33KW7@2,4NY4M@976	NA|NA|NA	S	Domain of unknown function (DUF4878)
MAG.T21.18_00548	745718.JADT01000011_gene834	2.1e-29	136.0	Flavobacteriia													Bacteria	1I2G6@117743,2A998@1,30YE4@2,4NPK8@976	NA|NA|NA	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MAG.T21.18_00549	1124780.ANNU01000061_gene910	4e-71	275.0	Cytophagia	dhaA	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.8.1.5	ko:K01563,ko:K22318	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120		R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000				Bacteria	47P83@768503,4NFBJ@976,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha/beta hydrolase family
MAG.T21.18_00550	1408433.JHXV01000003_gene229	5.3e-22	111.7	Bacteroidetes													Bacteria	4PKBQ@976,COG3209@1,COG3209@2,COG5384@1,COG5384@2	NA|NA|NA	J	extracellular matrix structural constituent
MAG.T21.18_00551	706587.Desti_0627	9.8e-35	152.9	Deltaproteobacteria													Bacteria	1N7EM@1224,2WQ28@28221,42U5G@68525,COG0614@1,COG0614@2	NA|NA|NA	P	PD-(D/E)XK nuclease superfamily
MAG.T21.18_00552	1416760.AYMS01000070_gene435	6.1e-246	856.7	Myroides	pccB		2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	1HY0V@117743,47H37@76831,4NEMJ@976,COG4799@1,COG4799@2	NA|NA|NA	I	Carboxyl transferase domain
MAG.T21.18_00553	523791.Kkor_1151	1.6e-34	152.9	Gammaproteobacteria													Bacteria	1PZAX@1224,1SEPK@1236,2CS66@1,32SQF@2	NA|NA|NA	S	Family of unknown function (DUF5343)
MAG.T21.18_00554	1120966.AUBU01000003_gene1474	2.4e-27	129.0	Bacteria													Bacteria	2B845@1,2ZIJ5@2	NA|NA|NA		
MAG.T21.18_00555	1033802.SSPSH_000547	1.5e-168	599.7	Gammaproteobacteria			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1MYDU@1224,1RNRV@1236,COG2865@1,COG2865@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.18_00556	1453500.AT05_07870	7.3e-46	191.4	Bacteria													Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_00557	1313421.JHBV01000041_gene3505	5.4e-233	814.3	Sphingobacteriia													Bacteria	1J102@117747,4NG09@976,COG3291@1,COG3291@2	NA|NA|NA	S	Fungalysin metallopeptidase (M36)
MAG.T21.18_00559	1358423.N180_07390	2.7e-59	235.0	Sphingobacteriia	paiA	GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007	2.3.1.57	ko:K22441					ko00000,ko01000				Bacteria	1IS8A@117747,4NP1E@976,COG0454@1,COG0456@2	NA|NA|NA	K	(GNAT) family
MAG.T21.18_00560	1296416.JACB01000026_gene3930	8.3e-188	663.7	Aquimarina													Bacteria	1HX0I@117743,2YKMC@290174,4NGKK@976,COG0457@1,COG0457@2,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.18_00561	1408433.JHXV01000006_gene2765	1.4e-35	157.9	Cryomorphaceae				ko:K03929					ko00000,ko01000		CE10		Bacteria	1IG13@117743,2PB7F@246874,4PI06@976,COG2272@1,COG2272@2	NA|NA|NA	I	Carboxylesterase family
MAG.T21.18_00563	657309.BXY_21720	5e-24	118.6	Bacteroidaceae													Bacteria	2G0FP@200643,4ANT5@815,4PKQ2@976,COG1680@1,COG1680@2	NA|NA|NA	V	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.18_00564	1384054.N790_09330	2.7e-35	155.2	Xanthomonadales													Bacteria	1MZ97@1224,1S8M3@1236,1XAU1@135614,2CHCP@1,32S5R@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_00566	1122176.KB903532_gene2680	5e-45	188.0	Sphingobacteriia	yiaD			ko:K02557	ko02030,ko02040,map02030,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	1IQFC@117747,4NEGF@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_00567	391937.NA2_19106	3.1e-47	194.9	Phyllobacteriaceae													Bacteria	1RDDG@1224,2U73S@28211,43K9N@69277,COG5649@1,COG5649@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_00568	307480.IW16_13765	5.7e-66	257.3	Chryseobacterium	ydeI												Bacteria	1HXYY@117743,3ZRG4@59732,4NG4C@976,COG4430@1,COG4430@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_00569	518766.Rmar_1077	2.9e-08	64.7	Bacteroidetes Order II. Incertae sedis													Bacteria	1FKEP@1100069,4NDXS@976,COG1629@1,COG1629@2,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent receptor plug
MAG.T21.18_00570	269798.CHU_2459	3.2e-110	405.2	Cytophagia	splB												Bacteria	47M4W@768503,4NE62@976,COG1533@1,COG1533@2	NA|NA|NA	L	SMART Elongator protein 3 MiaB NifB
MAG.T21.18_00571	1089547.KB913013_gene3106	1.6e-39	169.1	Cytophagia	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564		ko:K03664					ko00000				Bacteria	47QSI@768503,4NNJU@976,COG0691@1,COG0691@2	NA|NA|NA	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAG.T21.18_00572	755732.Fluta_0829	1.9e-52	214.2	Cryomorphaceae													Bacteria	1IMPV@117743,2PAU3@246874,4PAK3@976,COG5305@1,COG5305@2	NA|NA|NA	S	Dolichyl-phosphate-mannose-protein mannosyltransferase
MAG.T21.18_00573	1408433.JHXV01000006_gene2768	2.4e-61	242.7	Cryomorphaceae	ydiY			ko:K07283					ko00000				Bacteria	1HY5S@117743,2PAT9@246874,4NGB2@976,COG3137@1,COG3137@2	NA|NA|NA	M	Protein of unknown function (DUF3078)
MAG.T21.18_00574	984262.SGRA_1762	1.5e-35	156.8	Bacteroidetes	cmpX												Bacteria	4NH76@976,COG0668@1,COG0668@2	NA|NA|NA	M	Pfam Mechanosensitive ion channel
MAG.T21.18_00576	1349785.BAUG01000056_gene2481	1.8e-36	159.5	Flavobacteriia	sigX			ko:K03088					ko00000,ko03021				Bacteria	1I284@117743,4NNP4@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.18_00578	1121931.AUHG01000018_gene1380	9e-57	226.9	Flavobacteriia													Bacteria	1I0S1@117743,4NMV7@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase
MAG.T21.18_00579	755732.Fluta_2606	3.1e-104	385.2	Flavobacteriia													Bacteria	1I8RM@117743,28JI8@1,2Z9BM@2,4NE5E@976	NA|NA|NA	S	S1 P1 Nuclease
MAG.T21.18_00580	755732.Fluta_2607	9.1e-72	276.9	Cryomorphaceae	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000				Bacteria	1IMQY@117743,2PBHE@246874,4NG1A@976,COG2045@1,COG2045@2	NA|NA|NA	H	2-phosphosulpholactate phosphatase
MAG.T21.18_00581	1237149.C900_03998	2.2e-130	472.2	Cytophagia	gcvT		2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000				Bacteria	47MN7@768503,4NF7S@976,COG0404@1,COG0404@2	NA|NA|NA	E	The glycine cleavage system catalyzes the degradation of glycine
MAG.T21.18_00582	984262.SGRA_1047	5.5e-86	324.7	Bacteroidetes				ko:K07011					ko00000				Bacteria	4NJ6W@976,COG0438@1,COG0438@2	NA|NA|NA	M	Pfam Glycosyl transferases group 1
MAG.T21.18_00583	468059.AUHA01000002_gene1152	1.8e-145	523.1	Sphingobacteriia	capD		4.2.1.115,4.2.1.46	ko:K01710,ko:K15894	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPH4@117747,4NERY@976,COG1086@1,COG1086@2	NA|NA|NA	GM	Polysaccharide biosynthesis protein
MAG.T21.18_00584	1453500.AT05_06190	4.8e-40	170.6	Flavobacteriia													Bacteria	1I94U@117743,2BJ0K@1,32D95@2,4NQN9@976	NA|NA|NA		
MAG.T21.18_00585	1166018.FAES_1173	1.1e-88	333.6	Cytophagia	selU	GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360		ko:K06917					ko00000,ko01000,ko03016				Bacteria	47KFW@768503,4NH7W@976,COG2603@1,COG2603@2	NA|NA|NA	S	Rhodanese Homology Domain
MAG.T21.18_00586	754436.JCM19237_1447	3.1e-110	405.2	Vibrionales	selD	GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100		R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016			iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574	Bacteria	1MWFG@1224,1RQ5Q@1236,1XVXR@135623,COG0709@1,COG0709@2	NA|NA|NA	F	Synthesizes selenophosphate from selenide and ATP
MAG.T21.18_00588	118161.KB235922_gene2421	9.9e-34	149.8	Pleurocapsales				ko:K06149					ko00000				Bacteria	1G75A@1117,3VKQZ@52604,COG0589@1,COG0589@2	NA|NA|NA	T	Universal stress protein family
MAG.T21.18_00589	502025.Hoch_2003	2e-128	465.7	Myxococcales	MA20_25025												Bacteria	1MVK5@1224,2WKTF@28221,2YV31@29,42MU3@68525,COG2133@1,COG2133@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.18_00590	1121904.ARBP01000001_gene5713	2.3e-28	132.1	Bacteria													Bacteria	2E1HF@1,32WVJ@2	NA|NA|NA		
MAG.T21.18_00591	517418.Ctha_0665	4e-22	111.7	Chlorobi			3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	1FFPS@1090,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
MAG.T21.18_00592	515635.Dtur_1285	1.1e-10	74.7	Bacteria													Bacteria	COG1404@1,COG1404@2,COG1520@1,COG1520@2	NA|NA|NA	S	amino acid activation for nonribosomal peptide biosynthetic process
MAG.T21.18_00593	1123248.KB893321_gene465	2.2e-179	636.7	Sphingobacteriia													Bacteria	1IWJV@117747,4NF7B@976,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3391@1,COG3391@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.18_00594	1120965.AUBV01000014_gene1159	4.5e-96	358.2	Cytophagia	tolB			ko:K03641					ko00000,ko02000	2.C.1.2			Bacteria	47NVJ@768503,4NEPF@976,COG0823@1,COG0823@2	NA|NA|NA	U	WD40-like Beta Propeller Repeat
MAG.T21.18_00595	1313301.AUGC01000003_gene2076	2.5e-18	98.2	Bacteroidetes													Bacteria	2CKAK@1,32SBZ@2,4NSJ2@976	NA|NA|NA		
MAG.T21.18_00596	1118060.CAGZ01000005_gene1638	2.1e-33	148.7	Coriobacteriia	vsr		3.6.1.55	ko:K03574,ko:K07458					ko00000,ko01000,ko03400				Bacteria	2IKPY@201174,4CV6Q@84998,COG1051@1,COG1051@2,COG3727@1,COG3727@2	NA|NA|NA	L	DNA mismatch endonuclease vsr
MAG.T21.18_00597	709991.Odosp_2293	1.8e-13	84.0	Bacteroidia													Bacteria	2FYEG@200643,4P45T@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_00601	1168289.AJKI01000042_gene3700	4.7e-24	117.5	Marinilabiliaceae													Bacteria	2AD7J@1,2G24U@200643,312WH@2,3XK3Q@558415,4NR1A@976	NA|NA|NA	S	Domain of unknown function (DUF1987)
MAG.T21.18_00603	1121875.KB907548_gene1265	2e-25	122.9	Flavobacteriia													Bacteria	1HXKM@117743,2CCJ7@1,2ZA02@2,4NGH8@976	NA|NA|NA		
MAG.T21.18_00605	1506583.JQJY01000002_gene1258	1.1e-48	200.3	Flavobacterium	uspA												Bacteria	1HYE4@117743,2NT1B@237,4NFZ5@976,COG0589@1,COG0589@2	NA|NA|NA	T	Belongs to the universal stress protein A family
MAG.T21.18_00606	1279009.ADICEAN_00940	0.0	1609.0	Cytophagia				ko:K06894					ko00000				Bacteria	47MDC@768503,4NEW9@976,COG2373@1,COG2373@2	NA|NA|NA	S	Alpha-2-Macroglobulin
MAG.T21.18_00607	509635.N824_04660	2.8e-25	121.7	Sphingobacteriia													Bacteria	1IT47@117747,4NME2@976,COG0484@1,COG0484@2	NA|NA|NA	O	KTSC domain
MAG.T21.18_00609	1313421.JHBV01000031_gene1344	2.1e-84	320.1	Bacteroidetes			3.4.21.107,3.4.21.50	ko:K01337,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	4PKT1@976,COG0265@1,COG0265@2,COG3209@1,COG3209@2,COG3291@1,COG3291@2	NA|NA|NA	O	COG3209 Rhs family protein
MAG.T21.18_00610	485918.Cpin_0164	9.1e-195	687.2	Sphingobacteriia	pbpC		2.4.1.129	ko:K05367	ko00550,map00550				ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1IP6N@117747,4NEG5@976,COG4953@1,COG4953@2	NA|NA|NA	M	Penicillin-binding Protein
MAG.T21.18_00611	880074.BARVI_08080	3e-157	562.0	Porphyromonadaceae	ctpA		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	22WA5@171551,2FN98@200643,4NEGV@976,COG0793@1,COG0793@2	NA|NA|NA	M	Belongs to the peptidase S41A family
MAG.T21.18_00612	1237149.C900_03471	2.6e-23	115.5	Cytophagia													Bacteria	2CG1Y@1,31EK1@2,47XYM@768503,4NUTU@976	NA|NA|NA	S	Protein of unknown function (DUF1573)
MAG.T21.18_00613	1123276.KB893266_gene4475	4.7e-22	110.2	Cytophagia	phhB		4.2.1.96	ko:K01724	ko00790,map00790		R04734	RC01208	ko00000,ko00001,ko01000,ko04147				Bacteria	47RW0@768503,4NS9U@976,COG2154@1,COG2154@2	NA|NA|NA	H	PFAM Pterin 4 alpha carbinolamine dehydratase
MAG.T21.18_00614	1121904.ARBP01000002_gene7100	1.3e-203	716.5	Cytophagia	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03631					ko00000,ko03400				Bacteria	47YHC@768503,4PMJC@976,COG0497@1,COG0497@2	NA|NA|NA	L	Peptidase S46
MAG.T21.18_00615	1341181.FLJC2902T_15110	8.4e-55	222.2	Flavobacterium													Bacteria	1IKDI@117743,2P0DY@237,4PKPT@976,COG3386@1,COG3386@2	NA|NA|NA	G	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_00618	1122176.KB903534_gene2243	3.3e-29	135.2	Bacteroidetes				ko:K03088					ko00000,ko03021				Bacteria	4NR8J@976,COG1595@1,COG1595@2	NA|NA|NA	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
MAG.T21.18_00624	1122179.KB890436_gene1413	1.3e-52	213.8	Bacteroidetes				ko:K09992					ko00000				Bacteria	4NDVK@976,COG3828@1,COG3828@2	NA|NA|NA	C	trehalose utilisation
MAG.T21.18_00625	1223410.KN050846_gene1375	5.4e-112	411.4	Bacteroidetes				ko:K13735	ko05100,map05100				ko00000,ko00001				Bacteria	4P17V@976,COG2373@1,COG2373@2	NA|NA|NA	S	Large extracellular alpha-helical protein
MAG.T21.18_00626	383407.XOC_1694	5.6e-37	161.4	Xanthomonadales	ermC		2.1.1.137	ko:K07755					ko00000,ko01000				Bacteria	1NNRW@1224,1T8Z5@1236,1XBFC@135614,COG0500@1,COG2226@2	NA|NA|NA	Q	Nodulation protein S (NodS)
MAG.T21.18_00627	1313301.AUGC01000005_gene268	1.5e-43	183.3	Bacteroidetes													Bacteria	4NICK@976,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase domain
MAG.T21.18_00628	1237149.C900_03021	1.7e-156	559.3	Bacteroidetes			1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110		R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000				Bacteria	4NETM@976,COG1032@1,COG1032@2	NA|NA|NA	C	Fe-S oxidoreductase
MAG.T21.18_00629	1237149.C900_03022	1.6e-60	240.0	Bacteroidetes													Bacteria	4NPRU@976,COG1708@1,COG1708@2	NA|NA|NA	S	nucleotidyltransferase activity
MAG.T21.18_00630	1122176.KB903538_gene1452	8.3e-31	141.7	Bacteroidetes													Bacteria	28X89@1,2ZJ6D@2,4NM59@976	NA|NA|NA		
MAG.T21.18_00631	1122179.KB890469_gene474	1.6e-23	117.9	Bacteroidetes													Bacteria	4NWEX@976,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_00632	313606.M23134_06279	1.9e-187	662.5	Cytophagia			3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	47JGQ@768503,4NEXH@976,COG0308@1,COG0308@2	NA|NA|NA	E	PFAM Peptidase M1, membrane alanine aminopeptidase
MAG.T21.18_00633	161934.XP_010690865.1	2.5e-25	122.9	Streptophyta													Viridiplantae	37Y36@33090,3G8ZI@35493,COG0596@1,KOG1454@2759	NA|NA|NA	S	alpha/beta hydrolase fold
MAG.T21.18_00634	1122176.KB903548_gene1180	6.8e-175	621.3	Sphingobacteriia													Bacteria	1IPM9@117747,4NFQ6@976,COG2091@1,COG2091@2	NA|NA|NA	H	Carbohydrate family 9 binding domain-like
MAG.T21.18_00635	589865.DaAHT2_2072	3.7e-264	917.5	Desulfobacterales	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944		ko:K02355					ko00000,ko03012,ko03029				Bacteria	1R0V4@1224,2MHPT@213118,2WIYM@28221,42M1F@68525,COG0480@1,COG0480@2	NA|NA|NA	J	Elongation factor Tu domain 2
MAG.T21.18_00638	1500281.JQKZ01000004_gene3612	1.4e-08	67.8	Chryseobacterium													Bacteria	1HY4U@117743,3ZPCU@59732,4NESV@976,COG3391@1,COG3391@2	NA|NA|NA	S	amine dehydrogenase activity
MAG.T21.18_00640	153721.MYP_2624	3.7e-65	255.4	Cytophagia													Bacteria	47MUX@768503,4NG13@976,COG4772@1,COG4772@2	NA|NA|NA	P	TIGRFAM Bacteroidetes-specific
MAG.T21.18_00641	929556.Solca_2664	7e-121	443.0	Sphingobacteriia	htaA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.4.21.72	ko:K01347,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1IQYI@117747,4PKBQ@976,COG2374@1,COG2374@2,COG3209@1,COG3209@2,COG3210@1,COG3210@2,COG3391@1,COG3391@2,COG4886@1,COG4886@2,COG4932@1,COG4932@2,COG5492@1,COG5492@2	NA|NA|NA	M	SprB repeat
MAG.T21.18_00642	1197477.IA57_04790	8.8e-105	386.7	Flavobacteriia	zupT			ko:K07238					ko00000,ko02000	2.A.5.5			Bacteria	1HXM3@117743,4NGQ8@976,COG0428@1,COG0428@2	NA|NA|NA	P	divalent heavy-metal cations transporter
MAG.T21.18_00643	926562.Oweho_2418	3.1e-52	211.8	Cryomorphaceae	sirR			ko:K03709,ko:K11708	ko02010,map02010	M00319			ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.15			Bacteria	1HXI2@117743,2PASD@246874,4NGUP@976,COG1321@1,COG1321@2	NA|NA|NA	K	Iron dependent repressor, metal binding and dimerisation domain
MAG.T21.18_00644	485918.Cpin_0121	1.6e-236	825.9	Sphingobacteriia				ko:K02014,ko:K16089					ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10			Bacteria	1IQZ4@117747,4NF05@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.18_00647	313596.RB2501_01815	2.8e-70	271.9	Flavobacteriia	aroE		1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000				Bacteria	1HX5T@117743,4NEBJ@976,COG0169@1,COG0169@2	NA|NA|NA	E	Shikimate
MAG.T21.18_00648	1348583.ATLH01000013_gene2798	1.9e-74	286.2	Cellulophaga				ko:K08974					ko00000				Bacteria	1F91E@104264,1HYAC@117743,4NFKI@976,COG2035@1,COG2035@2	NA|NA|NA	S	Domain of unknown function (DUF368)
MAG.T21.18_00649	926549.KI421517_gene1987	3.2e-23	114.4	Cytophagia	moeB		2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122		R07459,R07461	RC00043	ko00000,ko00001,ko01000				Bacteria	47KG8@768503,4NFUD@976,COG0476@1,COG0476@2	NA|NA|NA	H	MoeZ MoeB domain
MAG.T21.18_00650	755732.Fluta_3660	5.7e-93	347.4	Cryomorphaceae	yitD		4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000				Bacteria	1IMQP@117743,2PBFH@246874,4NEHT@976,COG1809@1,COG1809@2	NA|NA|NA	S	(2R)-phospho-3-sulfolactate synthase (ComA)
MAG.T21.18_00651	860228.Ccan_12060	3.9e-36	159.5	Capnocytophaga													Bacteria	1ERJ3@1016,1HXHP@117743,4NG1I@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat protein
MAG.T21.18_00652	504472.Slin_2856	3e-161	575.1	Cytophagia	glmM		5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	47KR9@768503,4NG3H@976,COG1109@1,COG1109@2	NA|NA|NA	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I
MAG.T21.18_00653	1227739.Hsw_0361	2.9e-114	418.7	Cytophagia	iscS		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	47MAZ@768503,4NFF6@976,COG1104@1,COG1104@2	NA|NA|NA	E	PFAM aminotransferase class V
MAG.T21.18_00654	485917.Phep_1216	1.2e-52	213.0	Sphingobacteriia													Bacteria	1ISI3@117747,4NN31@976,COG0431@1,COG0431@2	NA|NA|NA	S	PFAM NADPH-dependent FMN reductase
MAG.T21.18_00655	761193.Runsl_5430	4.2e-32	144.1	Cytophagia	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02887	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	47QDB@768503,4NNKU@976,COG0292@1,COG0292@2	NA|NA|NA	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAG.T21.18_00656	1121904.ARBP01000006_gene3986	2.7e-14	84.0	Cytophagia	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02916	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	47RYG@768503,4NUVR@976,COG0291@1,COG0291@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL35 family
MAG.T21.18_00657	694427.Palpr_1224	2.4e-59	235.3	Porphyromonadaceae	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767		ko:K02520					ko00000,ko03012,ko03029				Bacteria	22X5B@171551,2FNF1@200643,4NIZ5@976,COG0290@1,COG0290@2	NA|NA|NA	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAG.T21.18_00658	1454007.JAUG01000091_gene683	1.7e-284	984.9	Sphingobacteriia	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IPWX@117747,4NEFT@976,COG0441@1,COG0441@2	NA|NA|NA	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAG.T21.18_00660	880070.Cycma_2338	5.7e-25	120.6	Cytophagia				ko:K15977					ko00000				Bacteria	47R97@768503,4NSBJ@976,COG2259@1,COG2259@2	NA|NA|NA	S	DoxX
MAG.T21.18_00661	1500281.JQKZ01000031_gene2438	2.8e-55	222.6	Chryseobacterium													Bacteria	1I8D0@117743,3ZPBH@59732,4NU2D@976,COG1215@1,COG1215@2	NA|NA|NA	M	Capsular biosynthesis protein CpsI
MAG.T21.18_00662	864073.HFRIS_012479	4.8e-33	148.7	Oxalobacteraceae	wbxA												Bacteria	1RDAK@1224,2VVXM@28216,47955@75682,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
MAG.T21.18_00663	867845.KI911784_gene1223	2.8e-36	159.5	Chloroflexi													Bacteria	2G8MG@200795,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_00664	1120963.KB894492_gene1695	5.9e-34	151.8	Pseudoalteromonadaceae	lgtA			ko:K00786					ko00000,ko01000				Bacteria	1QVAX@1224,1T3H7@1236,2Q5D3@267888,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_00665	1250006.JHZZ01000001_gene2284	3.5e-93	348.6	Polaribacter	wecB		5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1HXDA@117743,3VWNZ@52959,4NGBD@976,COG0381@1,COG0381@2	NA|NA|NA	M	UDP-N-acetylglucosamine 2-epimerase
MAG.T21.18_00666	886379.AEWI01000052_gene2670	7.3e-50	205.7	Marinilabiliaceae	rgpF			ko:K07011,ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	2G1JS@200643,3XKI2@558415,4NZMT@976,COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.18_00667	1123057.P872_01665	1.6e-89	336.3	Bacteria	galE		5.1.3.2,5.1.3.25,5.1.3.6	ko:K01784,ko:K08679,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R01385,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	COG1087@1,COG1087@2	NA|NA|NA	M	UDP-glucose 4-epimerase activity
MAG.T21.18_00668	886379.AEWI01000052_gene2669	6.1e-32	145.2	Marinilabiliaceae	tuaC	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176,ko:K16697,ko:K20430	ko00500,ko00525,ko01100,ko01110,ko01130,ko02026,ko04973,map00500,map00525,map01100,map01110,map01130,map02026,map04973	M00565,M00814	R02108,R02112,R02421,R11247,R11262	RC00005,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003		GH13,GT4,GT5	iYO844.BSU35590	Bacteria	2G144@200643,3XJT9@558415,4PP8M@976,COG0297@1,COG0297@2	NA|NA|NA	G	Glycosyltransferase Family 4
MAG.T21.18_00671	483219.LILAB_35380	2.5e-51	209.9	Deltaproteobacteria													Bacteria	1NRRA@1224,2C2BG@1,2WU3S@28221,32RA5@2,42YPP@68525	NA|NA|NA	S	CotH kinase protein
MAG.T21.18_00672	385682.AFSL01000001_gene1998	2.6e-56	226.5	Marinilabiliaceae													Bacteria	2CAAQ@1,2G24Y@200643,331TU@2,3XJU8@558415,4NTCJ@976	NA|NA|NA	S	O-antigen ligase like membrane protein
MAG.T21.18_00673	167548.EU98_1805	6.5e-66	259.2	Bacteria													Bacteria	28JA7@1,2Z951@2	NA|NA|NA		
MAG.T21.18_00675	243090.RB1819	4.7e-110	404.4	Planctomycetes			5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	2IWW0@203682,COG0451@1,COG0451@2	NA|NA|NA	GM	NAD- dependent epimerase dehydratase
MAG.T21.18_00676	880071.Fleli_1561	8e-178	630.6	Cytophagia	asnB		6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	47JSF@768503,4NFQ3@976,COG0367@1,COG0367@2	NA|NA|NA	E	Asparagine synthase
MAG.T21.18_00677	1408433.JHXV01000029_gene3118	3.5e-57	228.8	Bacteroidetes				ko:K12976					ko00000,ko01000,ko01005				Bacteria	4NQ11@976,COG3637@1,COG3637@2	NA|NA|NA	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MAG.T21.18_00678	926562.Oweho_0138	9.8e-124	449.9	Cryomorphaceae	fabK		1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1HYHD@117743,2PABG@246874,4NF8Z@976,COG2070@1,COG2070@2	NA|NA|NA	S	FMN-dependent dehydrogenase
MAG.T21.18_00679	1408433.JHXV01000004_gene3393	3.3e-92	346.3	Cryomorphaceae			1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000				Bacteria	1I7JN@117743,2PA5J@246874,4NUDC@976,COG2132@1,COG2132@2,COG3291@1,COG3291@2	NA|NA|NA	Q	C-terminal domain of CHU protein family
MAG.T21.18_00680	755732.Fluta_0943	2.6e-198	698.4	Cryomorphaceae	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147			iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	Bacteria	1HWYC@117743,2PAB5@246874,4NDXQ@976,COG0516@1,COG0516@2,COG0517@1,COG0517@2	NA|NA|NA	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MAG.T21.18_00681	1469557.JSWF01000034_gene839	7.1e-51	207.6	Flavobacteriia				ko:K06889					ko00000				Bacteria	1HYN3@117743,4NGCE@976,COG1073@1,COG1073@2	NA|NA|NA	S	Serine aminopeptidase, S33
MAG.T21.18_00682	761193.Runsl_2947	3.8e-48	198.4	Cytophagia			5.2.1.8	ko:K03772,ko:K03773					ko00000,ko01000,ko03110				Bacteria	47K8M@768503,4NDW4@976,COG0545@1,COG0545@2	NA|NA|NA	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
MAG.T21.18_00684	1382306.JNIM01000001_gene2905	1.1e-71	277.7	Chloroflexi	aceB	GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000			iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010	Bacteria	2G63R@200795,COG2225@1,COG2225@2	NA|NA|NA	H	Belongs to the malate synthase family
MAG.T21.18_00685	1121904.ARBP01000001_gene5820	5.6e-96	357.8	Cytophagia			1.14.15.3	ko:K00496,ko:K10616,ko:K15757	ko00071,ko00622,ko00623,ko00930,ko01100,ko01120,ko01220,map00071,map00622,map00623,map00930,map01100,map01120,map01220	M00419,M00537	R01347,R02281,R02550,R05266,R05288,R05442,R05443,R06945	RC00269,RC00478	ko00000,ko00001,ko00002,ko01000				Bacteria	47UEF@768503,4NIC2@976,COG3239@1,COG3239@2	NA|NA|NA	I	Fatty acid desaturase
MAG.T21.18_00686	886379.AEWI01000012_gene1067	1.7e-134	486.1	Marinilabiliaceae				ko:K07263					ko00000,ko01000,ko01002				Bacteria	2FWT4@200643,3XJC6@558415,4NEDZ@976,COG0612@1,COG0612@2	NA|NA|NA	S	Insulinase (Peptidase family M16)
MAG.T21.18_00687	886379.AEWI01000012_gene1068	3e-139	502.7	Marinilabiliaceae													Bacteria	2FX6V@200643,3XJ13@558415,4NEPT@976,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16 inactive domain
MAG.T21.18_00688	1279009.ADICEAN_01895	1.1e-97	363.6	Cytophagia	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576		ko:K03629,ko:K07459	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	47JMB@768503,4NFHN@976,COG1195@1,COG1195@2	NA|NA|NA	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAG.T21.18_00689	929703.KE386491_gene3319	4.8e-08	63.9	Cytophagia													Bacteria	47S8C@768503,4NXIK@976,COG5512@1,COG5512@2	NA|NA|NA	S	Protein of unknown function (DUF721)
MAG.T21.18_00690	760192.Halhy_0350	1.4e-44	185.7	Sphingobacteriia	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131				Bacteria	1ISC1@117747,4NM5B@976,COG0105@1,COG0105@2	NA|NA|NA	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MAG.T21.18_00691	1408433.JHXV01000010_gene508	2.9e-29	136.0	Cryomorphaceae													Bacteria	1IMS9@117743,29N3N@1,2PBW3@246874,33PNI@2,4P1TW@976	NA|NA|NA		
MAG.T21.18_00693	1249997.JHZW01000003_gene2084	2.3e-78	299.3	Maribacter	nrnA	GO:0008150,GO:0040007	2.7.7.72,3.1.13.3,3.1.3.7	ko:K00974,ko:K06881	ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013		R00188,R00508,R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03400				Bacteria	1HX3D@117743,2PH84@252356,4NEXE@976,COG0618@1,COG0618@2	NA|NA|NA	S	DHH family
MAG.T21.18_00694	755732.Fluta_0038	1.7e-18	99.4	Cryomorphaceae													Bacteria	1IC47@117743,2PB8G@246874,4NV96@976,COG0545@1,COG0545@2	NA|NA|NA	O	FKBP-type peptidyl-prolyl cis-trans isomerase
MAG.T21.18_00696	1270193.JARP01000001_gene2483	9.6e-22	111.7	Flavobacterium													Bacteria	1HY1Z@117743,2NSS7@237,4NE8J@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_00697	1356852.N008_06265	4.4e-52	211.5	Cytophagia	rsmI_1		2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	47N4G@768503,4NDXE@976,COG0313@1,COG0313@2	NA|NA|NA	H	PFAM Tetrapyrrole (Corrin Porphyrin) Methylases
MAG.T21.18_00698	311403.Arad_4382	8.5e-29	133.3	Rhizobiaceae	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104,ko:K20945	ko05111,map05111				ko00000,ko00001,ko01000				Bacteria	1RH90@1224,2U72X@28211,4BEFF@82115,COG0394@1,COG0394@2	NA|NA|NA	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAG.T21.18_00699	755732.Fluta_0001	4.5e-213	747.3	Cryomorphaceae	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837		ko:K02313	ko02020,ko04112,map02020,map04112				ko00000,ko00001,ko03032,ko03036				Bacteria	1HX45@117743,2PAFX@246874,4NE6Q@976,COG0593@1,COG0593@2	NA|NA|NA	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAG.T21.18_00700	1166018.FAES_1622	1.5e-36	159.1	Cytophagia	ybgC			ko:K07107					ko00000,ko01000				Bacteria	47Q99@768503,4NQGW@976,COG0824@1,COG0824@2	NA|NA|NA	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family
MAG.T21.18_00701	1123037.AUDE01000014_gene447	6.5e-39	167.9	Flavobacteriia													Bacteria	1HWX9@117743,4NGWA@976,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
MAG.T21.18_00702	761193.Runsl_3162	3.2e-75	288.9	Cytophagia	ribD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1624,iLJ478.TM1828	Bacteria	47KBG@768503,4NFJE@976,COG0117@1,COG0117@2,COG1985@1,COG1985@2	NA|NA|NA	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAG.T21.18_00703	385682.AFSL01000056_gene1967	1.8e-45	189.9	Marinilabiliaceae	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.297,2.1.1.298	ko:K02493,ko:K07320			R10806	RC00003,RC03279	ko00000,ko01000,ko03009,ko03012				Bacteria	2FM3H@200643,3XIW8@558415,4NDZB@976,COG2890@1,COG2890@2	NA|NA|NA	J	Ribosomal protein L11 methyltransferase (PrmA)
MAG.T21.18_00704	926562.Oweho_0750	3e-207	728.4	Cryomorphaceae	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1HXSG@117743,2PA5D@246874,4NE2X@976,COG0272@1,COG0272@2	NA|NA|NA	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAG.T21.18_00705	869213.JCM21142_73017	1.4e-13	83.2	Bacteroidetes													Bacteria	2ENX1@1,33GHZ@2,4NXFU@976	NA|NA|NA		
MAG.T21.18_00706	714943.Mucpa_1515	3.9e-98	364.8	Sphingobacteriia	dapA		4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	1INT7@117747,4NFP9@976,COG0329@1,COG0329@2	NA|NA|NA	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAG.T21.18_00707	1233950.IW22_07675	1.2e-42	179.9	Chryseobacterium	polC		2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1HXHA@117743,3ZUCP@59732,4NEQX@976,COG0847@1,COG0847@2	NA|NA|NA	L	EXOIII
MAG.T21.18_00709	1197477.IA57_07010	2.4e-18	99.0	Flavobacteriia	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360		ko:K02860					ko00000,ko03009				Bacteria	1I17F@117743,4NQF0@976,COG0806@1,COG0806@2	NA|NA|NA	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAG.T21.18_00710	1224318.DT73_25605	1.3e-40	173.3	Gammaproteobacteria	yfiC	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223,2.1.1.72	ko:K00571,ko:K15460					ko00000,ko01000,ko02048,ko03016				Bacteria	1PC8R@1224,1RM8S@1236,COG4123@1,COG4123@2	NA|NA|NA	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MAG.T21.18_00711	926562.Oweho_3166	2.7e-127	462.2	Cryomorphaceae	lys2		1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXRS@117743,2PAHF@246874,4NFM8@976,COG1748@1,COG1748@2	NA|NA|NA	E	Saccharopine dehydrogenase C-terminal domain
MAG.T21.18_00712	755732.Fluta_0866	7.5e-29	134.8	Flavobacteriia													Bacteria	1I2RK@117743,4NP4N@976,COG2913@1,COG2913@2	NA|NA|NA	J	Domain of unknown function (DUF4476)
MAG.T21.18_00713	1313301.AUGC01000001_gene1795	6.7e-57	228.4	Bacteroidetes													Bacteria	2BVGH@1,32QVC@2,4NQ4G@976	NA|NA|NA		
MAG.T21.18_00714	1313301.AUGC01000001_gene1794	1.6e-58	233.8	Bacteroidetes													Bacteria	2DMDZ@1,32QUA@2,4NSIY@976	NA|NA|NA	S	LPP20 lipoprotein
MAG.T21.18_00715	1313301.AUGC01000001_gene1771	5.9e-50	204.1	Bacteroidetes													Bacteria	2CC29@1,32RUM@2,4NS83@976	NA|NA|NA		
MAG.T21.18_00716	760192.Halhy_4884	9.2e-23	113.2	Sphingobacteriia	ywdK												Bacteria	1ITGX@117747,4NS8F@976,COG2363@1,COG2363@2	NA|NA|NA	S	small membrane protein
MAG.T21.18_00717	1408433.JHXV01000010_gene567	3.3e-220	771.2	Cryomorphaceae	pckA	GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS09060,iYO844.BSU30560	Bacteria	1HX6C@117743,2PA7A@246874,4NEGI@976,COG1866@1,COG1866@2	NA|NA|NA	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MAG.T21.18_00718	269798.CHU_2484	7.4e-22	112.1	Cytophagia			3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	47PB5@768503,4NGGJ@976,COG0793@1,COG0793@2	NA|NA|NA	M	PFAM Peptidase family S41
MAG.T21.18_00719	1173021.ALWA01000033_gene4265	1.1e-27	131.0	Cyanobacteria				ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1G37R@1117,COG0614@1,COG0614@2	NA|NA|NA	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component
MAG.T21.18_00720	1237149.C900_04059	2.3e-41	175.3	Cytophagia													Bacteria	47Q6B@768503,4NQIX@976,COG4539@1,COG4539@2	NA|NA|NA	S	Protein of unknown function (DUF962)
MAG.T21.18_00721	1123277.KB893172_gene1032	6.7e-17	92.8	Cytophagia	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9	ko:K01262					ko00000,ko01000,ko01002				Bacteria	47MAV@768503,4NG40@976,COG0006@1,COG0006@2	NA|NA|NA	E	Belongs to the peptidase M24B family
MAG.T21.18_00723	1408433.JHXV01000022_gene3142	1.5e-72	280.8	Cryomorphaceae													Bacteria	1I891@117743,2E09V@1,2PA81@246874,32VXB@2,4NY12@976	NA|NA|NA		
MAG.T21.18_00726	313606.M23134_06828	5e-46	191.4	Cytophagia				ko:K02477					ko00000,ko02022				Bacteria	47PTI@768503,4NFPV@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator of the LytR AlgR family
MAG.T21.18_00727	1408433.JHXV01000016_gene1822	6.4e-76	292.7	Cryomorphaceae													Bacteria	1HX37@117743,2PBB7@246874,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2	NA|NA|NA	T	Y_Y_Y domain
MAG.T21.18_00729	1408433.JHXV01000019_gene1917	1.4e-58	234.2	Flavobacteriia													Bacteria	1HYIP@117743,4NEGK@976,COG0535@1,COG0535@2	NA|NA|NA	S	radical SAM domain protein
MAG.T21.18_00730	1122621.ATZA01000064_gene1072	6.7e-126	457.2	Sphingobacteriia	thiL		2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000			iYO844.BSU05900	Bacteria	1IQ84@117747,4NDUT@976,COG0611@1,COG0611@2	NA|NA|NA	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MAG.T21.18_00731	1237149.C900_05190	2.1e-276	958.7	Cytophagia	dnaE-2		2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	47JNI@768503,4NE2R@976,COG0587@1,COG0587@2	NA|NA|NA	L	DNA polymerase III alpha subunit
MAG.T21.18_00732	760192.Halhy_3819	2.9e-293	1015.0	Sphingobacteriia				ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IPQP@117747,4NF3R@976,COG0308@1,COG0308@2,COG0842@1,COG0842@2,COG1277@1,COG1277@2	NA|NA|NA	E	Peptidase family M1 domain
MAG.T21.18_00733	1166018.FAES_5300	2e-115	422.2	Cytophagia				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	47KHD@768503,4NFWM@976,COG1131@1,COG1131@2	NA|NA|NA	V	ABC-type multidrug transport system ATPase component
MAG.T21.18_00734	1121405.dsmv_3077	7.9e-38	165.6	Bacteria													Bacteria	COG3420@1,COG3420@2	NA|NA|NA	P	alginic acid biosynthetic process
MAG.T21.18_00735	592029.DDD_0487	5.2e-123	447.6	Flavobacteriia	yneE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K08994					ko00000,ko02000	1.A.46.2			Bacteria	1HYG9@117743,4NGJ0@976,COG3781@1,COG3781@2	NA|NA|NA	S	Multidrug transporter
MAG.T21.18_00736	558152.IQ37_13865	4.1e-29	134.4	Chryseobacterium													Bacteria	1I4T8@117743,2E5BW@1,3303Y@2,3ZSMB@59732,4NSA8@976	NA|NA|NA		
MAG.T21.18_00737	421531.IX38_21015	6.7e-38	163.3	Chryseobacterium													Bacteria	1I3K4@117743,2CIJ2@1,32S86@2,3ZSBR@59732,4NSRA@976	NA|NA|NA		
MAG.T21.18_00738	1396418.BATQ01000168_gene1822	5.9e-51	207.6	Verrucomicrobia													Bacteria	46V39@74201,COG0551@1,COG0551@2	NA|NA|NA	L	23S rRNA-intervening sequence protein
MAG.T21.18_00739	1004149.AFOE01000048_gene33	3.3e-148	531.6	Flavobacteriia	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346					ko00000,ko01000,ko03400				Bacteria	1HXFK@117743,4NE9N@976,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAG.T21.18_00740	643867.Ftrac_1573	4.1e-37	160.6	Cytophagia	sufA			ko:K13628					ko00000,ko03016				Bacteria	47QAX@768503,4NQC8@976,COG0316@1,COG0316@2	NA|NA|NA	S	Belongs to the HesB IscA family
MAG.T21.18_00741	926562.Oweho_2654	1.1e-222	779.2	Cryomorphaceae	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840		ko:K07033,ko:K09014					ko00000			iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	Bacteria	1HWKU@117743,2PA9Y@246874,4NFXH@976,COG0719@1,COG0719@2	NA|NA|NA	O	Uncharacterized protein family (UPF0051)
MAG.T21.18_00742	1270196.JCKI01000002_gene473	4e-90	338.6	Bacteroidetes	cdu2												Bacteria	4NK07@976,COG0025@1,COG0025@2	NA|NA|NA	P	Pfam Sodium hydrogen exchanger
MAG.T21.18_00743	1408473.JHXO01000013_gene605	4e-188	664.5	Bacteroidia	yhcX			ko:K11206					ko00000,ko01000				Bacteria	2FNGK@200643,4NEAQ@976,COG0388@1,COG0388@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.18_00744	1408433.JHXV01000012_gene3968	1e-10	72.8	Bacteria				ko:K03286					ko00000,ko02000	1.B.6			Bacteria	COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.18_00745	1004149.AFOE01000039_gene989	7.2e-27	127.5	Flavobacteriia	sigX			ko:K03088					ko00000,ko03021				Bacteria	1I284@117743,4NNP4@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.18_00746	649638.Trad_0565	6.7e-73	280.8	Deinococcus-Thermus	kch			ko:K10716					ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6			Bacteria	1WM74@1297,COG2126@1,COG2126@2	NA|NA|NA	J	Ion transport protein
MAG.T21.18_00747	1124780.ANNU01000012_gene3907	7e-101	373.6	Cytophagia	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840		ko:K09013					ko00000,ko02000			iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	Bacteria	47N88@768503,4NEMY@976,COG0396@1,COG0396@2	NA|NA|NA	O	TIGRFAM FeS assembly ATPase SufC
MAG.T21.18_00748	755732.Fluta_2086	4.6e-68	265.4	Cryomorphaceae	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840		ko:K07033,ko:K09015					ko00000			iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	Bacteria	1HXNA@117743,2PAU0@246874,4NFPG@976,COG0719@1,COG0719@2	NA|NA|NA	O	Uncharacterized protein family (UPF0051)
MAG.T21.18_00749	1122176.KB903541_gene168	5.1e-136	491.1	Sphingobacteriia	sufS		2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100		R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000				Bacteria	1IP7B@117747,4NDUB@976,COG0520@1,COG0520@2	NA|NA|NA	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAG.T21.18_00750	411154.GFO_3127	4.7e-44	184.1	Flavobacteriia	sufE			ko:K02426					ko00000				Bacteria	1I187@117743,4NM9N@976,COG2166@1,COG2166@2	NA|NA|NA	S	SufE protein probably involved in Fe-S center assembly
MAG.T21.18_00751	421072.IO89_04640	1.5e-31	142.5	Chryseobacterium	paaD			ko:K02612	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1I2WQ@117743,3HI9C@358033,4NSA9@976,COG2151@1,COG2151@2	NA|NA|NA	S	Pfam:DUF59
MAG.T21.18_00752	1089547.KB913013_gene2913	8.4e-53	213.4	Cytophagia													Bacteria	28NIX@1,2ZBK6@2,47MBS@768503,4NMEI@976	NA|NA|NA	S	Protein of unknown function (DUF2480)
MAG.T21.18_00753	1313421.JHBV01000039_gene2629	3.8e-11	77.0	Bacteroidetes													Bacteria	2F1WD@1,33UW2@2,4P2AY@976	NA|NA|NA		
MAG.T21.18_00754	1227739.Hsw_0105	1.4e-54	220.7	Cytophagia													Bacteria	28MIW@1,2ZAVI@2,47UX4@768503,4P3DI@976	NA|NA|NA		
MAG.T21.18_00755	926562.Oweho_2634	2.6e-240	838.2	Cryomorphaceae	purF		2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1HXZE@117743,2PAAI@246874,4NFSM@976,COG0034@1,COG0034@2	NA|NA|NA	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MAG.T21.18_00756	1408433.JHXV01000014_gene3680	3.8e-267	928.3	Cryomorphaceae													Bacteria	1IG7B@117743,2PBE8@246874,4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	S	C-terminal domain of CHU protein family
MAG.T21.18_00757	1356852.N008_07390	8.3e-137	493.4	Cytophagia			4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000				Bacteria	47KJH@768503,4NIGJ@976,COG2159@1,COG2159@2	NA|NA|NA	S	Amidohydrolase
MAG.T21.18_00758	755732.Fluta_2018	1.7e-72	278.9	Cryomorphaceae	nbaC		1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000				Bacteria	1IJAI@117743,2PAU2@246874,4PKJ0@976,COG1917@1,COG1917@2	NA|NA|NA	H	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate
MAG.T21.18_00760	760192.Halhy_6848	4.3e-114	419.9	Bacteroidetes				ko:K13735	ko05100,map05100				ko00000,ko00001				Bacteria	4NKIK@976,COG4932@1,COG4932@2	NA|NA|NA	M	domain protein
MAG.T21.18_00762	391587.KAOT1_12767	3.6e-48	200.3	Flavobacteriia													Bacteria	1HY1K@117743,4NFVP@976,COG1345@1,COG1345@2,COG3291@1,COG3291@2	NA|NA|NA	N	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MAG.T21.18_00763	926562.Oweho_2602	1.2e-71	276.6	Cryomorphaceae													Bacteria	1HY8Z@117743,2PA73@246874,4NICN@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	Enoyl-(Acyl carrier protein) reductase
MAG.T21.18_00764	1121957.ATVL01000006_gene2766	4.4e-35	155.6	Cytophagia													Bacteria	47R0V@768503,4NJHV@976,COG3291@1,COG3291@2	NA|NA|NA	S	Fibronectin type 3 domain
MAG.T21.18_00765	886377.Murru_1788	2.7e-07	62.8	Flavobacteriia				ko:K03832					ko00000,ko02000	2.C.1.1			Bacteria	1HX5H@117743,4NMG7@976,COG0810@1,COG0810@2	NA|NA|NA	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.18_00766	1236514.BAKL01000017_gene1835	8.1e-75	287.0	Bacteroidaceae													Bacteria	2FNZV@200643,4AKWQ@815,4NF1I@976,COG0745@1,COG0745@2	NA|NA|NA	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.18_00767	880071.Fleli_2412	1.5e-62	247.3	Cytophagia	rprX		2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	47MII@768503,4PKBV@976,COG5002@1,COG5002@2	NA|NA|NA	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_00768	1144275.COCOR_00871	1.2e-181	642.9	Myxococcales	amnC		1.2.1.32,1.2.1.60,1.2.1.85	ko:K00151,ko:K10217	ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00350,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00533,M00569	R02762,R03889,R04418,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000				Bacteria	1MU1V@1224,2WJQQ@28221,2YTZ3@29,42N0C@68525,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
MAG.T21.18_00769	1313301.AUGC01000003_gene1976	4.7e-10	72.4	Bacteroidetes													Bacteria	2AAU0@1,3106Q@2,4NNSV@976	NA|NA|NA		
MAG.T21.18_00771	1121918.ARWE01000001_gene2423	1.4e-37	162.9	Deltaproteobacteria	YH67_14670												Bacteria	1R79M@1224,2X5BT@28221,42N61@68525,COG2928@1,COG2928@2	NA|NA|NA	S	Protein of unknown function (DUF502)
MAG.T21.18_00772	926556.Echvi_2122	8.4e-36	156.4	Cytophagia													Bacteria	47R6I@768503,4NS6J@976,COG2315@1,COG2315@2	NA|NA|NA	S	YjbR
MAG.T21.18_00773	1317122.ATO12_07860	3.6e-68	265.0	Aquimarina													Bacteria	1HWQP@117743,2YH8K@290174,4NFXM@976,COG1878@1,COG1878@2	NA|NA|NA	S	Putative cyclase
MAG.T21.18_00774	925409.KI911562_gene1149	5.7e-80	304.7	Sphingobacteriia	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576										iNJ661.Rv2388c	Bacteria	1IR75@117747,4NFEE@976,COG0635@1,COG0635@2	NA|NA|NA	H	Involved in the biosynthesis of porphyrin-containing compound
MAG.T21.18_00775	755732.Fluta_0377	5.6e-97	361.7	Cryomorphaceae	vicK		2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035				Bacteria	1HY7G@117743,2PAKB@246874,4NEMP@976,COG4191@1,COG4191@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
MAG.T21.18_00776	926562.Oweho_2765	2.5e-76	293.9	Cryomorphaceae				ko:K09800					ko00000,ko02000				Bacteria	1HZTJ@117743,2PAS8@246874,4NHD3@976,COG2982@1,COG2982@2	NA|NA|NA	M	AsmA-like C-terminal region
MAG.T21.18_00777	1122621.ATZA01000045_gene3571	1.1e-83	317.0	Sphingobacteriia	rluB		5.4.99.19,5.4.99.22	ko:K06178,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1INNI@117747,4NEE1@976,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
MAG.T21.18_00778	1158294.JOMI01000007_gene511	6.4e-26	123.6	Bacteroidia	yraN			ko:K07460					ko00000				Bacteria	2FSN9@200643,4NS7E@976,COG0792@1,COG0792@2	NA|NA|NA	L	Belongs to the UPF0102 family
MAG.T21.18_00779	452637.Oter_2380	3.9e-07	62.0	Bacteria													Bacteria	2ETF9@1,33KZ8@2	NA|NA|NA	S	Domain of unknown function (DUF4412)
MAG.T21.18_00780	1223410.KN050846_gene1651	9.7e-84	317.0	Flavobacteriia	ykfA		3.4.17.13	ko:K01297					ko00000,ko01000,ko01002,ko01011				Bacteria	1HXC6@117743,4NF5Q@976,COG1619@1,COG1619@2	NA|NA|NA	V	proteins, homologs of microcin C7 resistance protein MccF
MAG.T21.18_00781	1124780.ANNU01000045_gene2285	9.4e-236	823.2	Cytophagia	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.20	ko:K01874,ko:K01890,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Bacteria	47JB3@768503,4NECB@976,COG0073@1,COG0073@2,COG0143@1,COG0143@2	NA|NA|NA	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAG.T21.18_00782	1322246.BN4_11207	1.3e-40	174.9	Bacteria			2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0574@1,COG0574@2	NA|NA|NA	G	Belongs to the PEP-utilizing enzyme family
MAG.T21.18_00783	468059.AUHA01000002_gene1130	3e-90	338.2	Sphingobacteriia	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRA4@117747,4NFER@976,COG0047@1,COG0047@2	NA|NA|NA	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAG.T21.18_00784	762903.Pedsa_3214	5.3e-08	65.5	Bacteroidetes													Bacteria	2EUJZ@1,33N1X@2,4NYSW@976	NA|NA|NA		
MAG.T21.18_00786	755732.Fluta_1840	1.3e-137	496.5	Cryomorphaceae	purD		6.3.4.13,6.3.5.3	ko:K01945,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04463	RC00010,RC00090,RC00166,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXGE@117743,2PA57@246874,4NEUN@976,COG0151@1,COG0151@2	NA|NA|NA	F	Phosphoribosylglycinamide synthetase, C domain
MAG.T21.18_00787	518766.Rmar_0035	1.1e-49	203.4	Bacteroidetes													Bacteria	4NMEK@976,COG1225@1,COG1225@2	NA|NA|NA	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.18_00788	1250006.JHZZ01000001_gene924	2.2e-42	179.1	Polaribacter													Bacteria	1ICD1@117743,3VX57@52959,4PIAP@976,COG2197@1,COG2197@2	NA|NA|NA	T	helix_turn_helix, Lux Regulon
MAG.T21.18_00789	760192.Halhy_1196	3.1e-43	183.3	Sphingobacteriia													Bacteria	1IRZC@117747,4NI65@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor
MAG.T21.18_00790	926562.Oweho_2126	2.6e-227	794.7	Cryomorphaceae	pccB		2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYE9@117743,2PAEZ@246874,4NEMJ@976,COG4799@1,COG4799@2	NA|NA|NA	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)
MAG.T21.18_00791	351160.RCIX1753	3.3e-38	166.8	Archaea													Archaea	COG3920@1,arCOG02335@2157	NA|NA|NA	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor
MAG.T21.18_00792	525257.HMPREF0204_10801	1.1e-66	260.0	Chryseobacterium	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1HY9V@117743,3ZPU9@59732,4NE8Y@976,COG0217@1,COG0217@2	NA|NA|NA	K	transcriptional regulatory protein
MAG.T21.18_00793	1168289.AJKI01000002_gene2694	2.7e-23	116.3	Marinilabiliaceae													Bacteria	28NPZ@1,2FPEH@200643,2ZBPQ@2,3XJXJ@558415,4NN3K@976	NA|NA|NA	S	Outer membrane protein beta-barrel domain
MAG.T21.18_00795	1408473.JHXO01000001_gene2031	1.7e-12	80.9	Bacteroidia													Bacteria	2DP4F@1,2FVZZ@200643,330H1@2,4NX9Z@976	NA|NA|NA		
MAG.T21.18_00796	1408473.JHXO01000001_gene2032	2.9e-39	168.3	Bacteroidia				ko:K03088					ko00000,ko03021				Bacteria	2FTDI@200643,4NQ7S@976,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70, region 4
MAG.T21.18_00797	1484460.JSWG01000009_gene190	3.7e-42	178.7	Bacteroidetes													Bacteria	4PNX4@976,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_00798	1173024.KI912149_gene6079	8e-40	170.2	Stigonemataceae	wcaB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.30	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000			iECW_1372.ECW_m2215,iWFL_1372.ECW_m2215	Bacteria	1GHYE@1117,1JINP@1189,COG1045@1,COG1045@2	NA|NA|NA	E	Bacterial transferase hexapeptide (six repeats)
MAG.T21.18_00799	929556.Solca_1161	3.4e-10	72.4	Bacteroidetes													Bacteria	4NW46@976,COG1280@1,COG1280@2	NA|NA|NA	E	LysE type translocator
MAG.T21.18_00800	882.DVU_0134	4.3e-77	295.0	Desulfovibrionales	exoO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	4.2.1.115	ko:K15894,ko:K16555,ko:K16564	ko00520,map00520		R09697	RC02609	ko00000,ko00001,ko01000,ko01003		GT2		Bacteria	1R988@1224,2MG4E@213115,2WM6J@28221,42QKI@68525,COG1086@1,COG1086@2,COG1215@1,COG1215@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.18_00801	1250232.JQNJ01000001_gene2276	2.6e-10	72.8	Flavobacteriia													Bacteria	1HXB0@117743,4NH7M@976,COG1566@1,COG1566@2	NA|NA|NA	V	Protein of unknown function (DUF3667)
MAG.T21.18_00802	926562.Oweho_2554	1.5e-197	696.0	Cryomorphaceae	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1HWQN@117743,2PAIQ@246874,4NE61@976,COG0322@1,COG0322@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAG.T21.18_00803	1278073.MYSTI_07731	4e-175	622.5	Proteobacteria													Bacteria	1R66T@1224,COG3391@1,COG3391@2	NA|NA|NA	C	amine dehydrogenase activity
MAG.T21.18_00804	1201288.M900_1475	1.6e-125	456.4	Bdellovibrionales			1.2.1.3,1.2.1.9	ko:K00128,ko:K00131	ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00135,M00308,M00633	R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000				Bacteria	1MU1V@1224,2MUQC@213481,2WJQQ@28221,42N0C@68525,COG1012@1,COG1012@2	NA|NA|NA	C	Aldehyde dehydrogenase family
MAG.T21.18_00805	1121904.ARBP01000053_gene482	2.8e-89	335.5	Cytophagia													Bacteria	47TR3@768503,4NGS4@976,COG4927@1,COG4927@2	NA|NA|NA	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
MAG.T21.18_00806	667015.Bacsa_0552	3.4e-30	137.9	Bacteroidaceae													Bacteria	2FTYU@200643,4ARYV@815,4NTHD@976,COG0614@1,COG0614@2	NA|NA|NA	P	PD-(D/E)XK nuclease superfamily
MAG.T21.18_00807	1120951.AUBG01000003_gene2783	9.4e-127	459.9	Flavobacteriia			6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000				Bacteria	1IKCX@117743,4PP09@976,COG0189@1,COG0189@2	NA|NA|NA	HJ	ligase activity
MAG.T21.18_00808	468059.AUHA01000005_gene2431	4e-152	544.7	Sphingobacteriia	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000			iHN637.CLJU_RS08925	Bacteria	1INX8@117747,4NFVB@976,COG0213@1,COG0213@2	NA|NA|NA	F	Glycosyl transferase family, helical bundle domain
MAG.T21.18_00809	1122176.KB903533_gene2317	1.2e-102	379.8	Sphingobacteriia			2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	1IVYQ@117747,4NFX7@976,COG0462@1,COG0462@2	NA|NA|NA	EF	Belongs to the ribose-phosphate pyrophosphokinase family
MAG.T21.18_00810	755732.Fluta_0614	2.2e-15	89.7	Cryomorphaceae													Bacteria	1I4H2@117743,2DQEZ@1,2PBW4@246874,336F0@2,4NUK8@976	NA|NA|NA	S	Reeler domain
MAG.T21.18_00811	1121875.KB907548_gene1268	1.6e-73	283.5	Flavobacteriia			1.11.1.15	ko:K03564					ko00000,ko01000				Bacteria	1HY6E@117743,4NEEA@976,COG1225@1,COG1225@2	NA|NA|NA	O	Redoxin
MAG.T21.18_00812	1121957.ATVL01000006_gene3386	6.2e-11	75.1	Cytophagia													Bacteria	2C85E@1,335NV@2,47S04@768503,4NVTV@976	NA|NA|NA		
MAG.T21.18_00813	761193.Runsl_5934	2.3e-157	562.0	Cytophagia			3.1.21.4	ko:K01155					ko00000,ko01000,ko02048				Bacteria	28HKD@1,2Z7V8@2,47KMD@768503,4NISU@976	NA|NA|NA	S	type ii restriction enzyme
MAG.T21.18_00815	761193.Runsl_1636	1.7e-53	216.9	Cytophagia	czcC			ko:K15725,ko:K15726					ko00000,ko02000	1.B.17.2.2,2.A.6.1.2			Bacteria	47Q8E@768503,4NPS6@976,COG1538@1,COG1538@2	NA|NA|NA	MU	Outer membrane efflux protein
MAG.T21.18_00816	1123276.KB893311_gene3163	3.3e-103	382.5	Cytophagia				ko:K15727					ko00000,ko02000	8.A.1.2.1			Bacteria	47PN9@768503,4NJ59@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.18_00817	925409.KI911562_gene1725	2.9e-63	249.2	Sphingobacteriia													Bacteria	1IT23@117747,4NRDG@976,COG4244@1,COG4244@2	NA|NA|NA	S	Membrane
MAG.T21.18_00818	1123276.KB893311_gene3165	0.0	1396.3	Cytophagia	czcA			ko:K07239,ko:K07787	ko02020,map02020				ko00000,ko00001,ko02000	2.A.6.1,2.A.6.1.4			Bacteria	47JFH@768503,4P36A@976,COG3696@1,COG3696@2	NA|NA|NA	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.18_00819	1122918.KB907289_gene4420	7.8e-58	231.1	Paenibacillaceae													Bacteria	1TT37@1239,271TF@186822,28HNP@1,2Z7WV@2,4HVDG@91061	NA|NA|NA	S	Psort location Cytoplasmic, score
MAG.T21.18_00821	925409.KI911562_gene1726	6.4e-15	87.4	Bacteroidetes													Bacteria	2CBQ4@1,33DR4@2,4NZ1W@976	NA|NA|NA		
MAG.T21.18_00822	1296415.JACC01000006_gene1495	3.7e-61	241.5	Bacteroidetes													Bacteria	4NS4G@976,COG0500@1,COG2226@2	NA|NA|NA	Q	ubiE/COQ5 methyltransferase family
MAG.T21.18_00823	1484460.JSWG01000008_gene1892	4e-112	412.1	Flavobacteriia			1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110		R02394	RC01983	ko00000,ko00001,ko01000				Bacteria	1HZIA@117743,4NE3N@976,COG2132@1,COG2132@2	NA|NA|NA	Q	Multicopper oxidase
MAG.T21.18_00824	926562.Oweho_1991	3.7e-77	296.2	Cryomorphaceae													Bacteria	1HZ7Y@117743,2PBDM@246874,4NGRJ@976,COG3291@1,COG3291@2	NA|NA|NA	O	PFAM Pregnancy-associated plasma protein-A
MAG.T21.18_00825	1233950.IW22_15455	2.4e-08	65.9	Chryseobacterium													Bacteria	1II89@117743,3ZNRR@59732,4NN3N@976,COG3291@1,COG3291@2	NA|NA|NA	S	PKD domain
MAG.T21.18_00826	1122176.KB903533_gene2292	1e-162	580.5	Bacteria													Bacteria	COG3055@1,COG3055@2	NA|NA|NA	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MAG.T21.18_00827	1227739.Hsw_1163	7.8e-16	90.1	Cytophagia				ko:K08364					ko00000,ko02000	1.A.72.1			Bacteria	47S0M@768503,4NUTQ@976,COG2608@1,COG2608@2	NA|NA|NA	P	PFAM Heavy metal transport detoxification protein
MAG.T21.18_00829	1408473.JHXO01000009_gene3230	2.1e-12	79.0	Bacteria													Bacteria	290IA@1,2ZN74@2	NA|NA|NA		
MAG.T21.18_00830	616991.JPOO01000001_gene3356	3.7e-157	561.6	Flavobacteriia	yibN		2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122		R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000				Bacteria	1HZ4T@117743,4NEN9@976,COG0477@1,COG0607@1,COG0607@2,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.18_00832	1229276.DI53_3440	0.0	1378.2	Sphingobacteriia	czcA			ko:K15726					ko00000,ko02000	2.A.6.1.2			Bacteria	1IQBJ@117747,4P36A@976,COG3696@1,COG3696@2	NA|NA|NA	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.18_00833	1218103.CIN01S_07_00580	2.5e-67	263.1	Chryseobacterium				ko:K15727					ko00000,ko02000	8.A.1.2.1			Bacteria	1HXZJ@117743,3ZRCW@59732,4NDW5@976,COG0845@1,COG0845@2	NA|NA|NA	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion
MAG.T21.18_00834	929556.Solca_0451	1.4e-209	736.1	Sphingobacteriia	cadA		3.6.3.3,3.6.3.5	ko:K01534					ko00000,ko01000	3.A.3.6			Bacteria	1IPUI@117747,4NERS@976,COG2217@1,COG2217@2	NA|NA|NA	P	Metal ABC transporter ATPase
MAG.T21.18_00835	1086011.HJ01_03286	1.5e-48	199.5	Flavobacteriia													Bacteria	1I33F@117743,2C1H5@1,32R8P@2,4NS5E@976	NA|NA|NA	S	Domain of unknown function (DUF4136)
MAG.T21.18_00836	1444711.CCJF01000003_gene89	1.2e-173	616.3	Chlamydiae				ko:K07576					ko00000				Bacteria	2JFRH@204428,COG1236@1,COG1236@2	NA|NA|NA	J	exonuclease of the beta-lactamase fold involved in RNA processing
MAG.T21.18_00837	1122176.KB903533_gene2302	3.3e-23	115.2	Bacteroidetes													Bacteria	2EJH1@1,33D7Y@2,4NXTD@976	NA|NA|NA		
MAG.T21.18_00838	1121011.AUCB01000013_gene236	1.6e-76	292.7	Arenibacter													Bacteria	1HWS5@117743,23GQM@178469,4NFJ5@976,COG2326@1,COG2326@2	NA|NA|NA	S	Polyphosphate kinase 2 (PPK2)
MAG.T21.18_00839	269798.CHU_1504	5.3e-165	587.4	Cytophagia	cusA	GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169		ko:K07787,ko:K15726	ko02020,map02020				ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4		iAF987.Gmet_1547,iB21_1397.B21_00525,iECBD_1354.ECBD_3087,iECB_1328.ECB_00536,iECD_1391.ECD_00536	Bacteria	47N7N@768503,4P36A@976,COG3696@1,COG3696@2	NA|NA|NA	P	AcrB/AcrD/AcrF family
MAG.T21.18_00840	761193.Runsl_5945	4.7e-226	790.8	Cytophagia	cusA	GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169		ko:K07787,ko:K15726	ko02020,map02020				ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4		iAF987.Gmet_1547,iB21_1397.B21_00525,iECBD_1354.ECBD_3087,iECB_1328.ECB_00536,iECD_1391.ECD_00536	Bacteria	47N7N@768503,4P36A@976,COG3696@1,COG3696@2	NA|NA|NA	P	AcrB/AcrD/AcrF family
MAG.T21.18_00841	1250232.JQNJ01000001_gene29	1.1e-88	334.0	Flavobacteriia													Bacteria	1HYVZ@117743,4NKP6@976,COG3174@1,COG3174@2	NA|NA|NA	S	Domain of unknown function (DUF4010)
MAG.T21.18_00842	269798.CHU_1503	9.3e-101	374.0	Cytophagia													Bacteria	47KYU@768503,4NFEC@976,COG1538@1,COG1538@2	NA|NA|NA	MU	Outer membrane efflux protein
MAG.T21.18_00843	1123248.KB893370_gene4945	9.2e-58	231.1	Sphingobacteriia	crdC			ko:K07798,ko:K15727	ko02020,map02020				ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1			Bacteria	1IS3S@117747,4NG8S@976,COG0845@1,COG0845@2	NA|NA|NA	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion
MAG.T21.18_00844	525257.HMPREF0204_14940	9.6e-84	317.4	Chryseobacterium	crdC			ko:K07798,ko:K15727	ko02020,map02020				ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1			Bacteria	1HYRA@117743,3ZPJ1@59732,4NG8S@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.18_00845	1120965.AUBV01000008_gene2020	2.1e-82	312.4	Cytophagia	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564		ko:K03694,ko:K03695	ko04213,map04213				ko00000,ko00001,ko03110				Bacteria	47KA7@768503,4NGEM@976,COG0542@1,COG0542@2	NA|NA|NA	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAG.T21.18_00846	755732.Fluta_4041	3.3e-65	255.0	Cryomorphaceae	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564		ko:K03694,ko:K03695	ko04213,map04213				ko00000,ko00001,ko03110				Bacteria	1HXRE@117743,2PAB7@246874,4NGEM@976,COG0542@1,COG0542@2	NA|NA|NA	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAG.T21.18_00847	1392490.JHZX01000001_gene1920	1.2e-110	408.7	Bacteria													Bacteria	COG3291@1,COG3291@2,COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_00848	1313421.JHBV01000014_gene4035	1.5e-129	470.3	Sphingobacteriia			3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142				ko00000,ko00001,ko01000				Bacteria	1INWW@117747,4NE7H@976,COG3250@1,COG3250@2	NA|NA|NA	G	PFAM Glycoside hydrolase family 2
MAG.T21.18_00849	1515615.HQ41_06520	1.2e-30	140.2	Porphyromonadaceae	cutC	GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771		ko:K06201					ko00000				Bacteria	22XRN@171551,2FN71@200643,4NINY@976,COG3142@1,COG3142@2	NA|NA|NA	P	Participates in the control of copper homeostasis
MAG.T21.18_00850	1185876.BN8_04054	7.9e-32	145.6	Cytophagia	pdtaS		2.7.13.3	ko:K00936		M00839			ko00000,ko00002,ko01000,ko01001,ko02022				Bacteria	47JHQ@768503,4NINT@976,COG0457@1,COG0457@2,COG3920@1,COG3920@2	NA|NA|NA	T	ATP-binding region ATPase domain protein
MAG.T21.18_00851	525373.HMPREF0766_12032	4.5e-121	441.4	Sphingobacteriia	deaD												Bacteria	1IR44@117747,4NEVI@976,COG0513@1,COG0513@2	NA|NA|NA	L	Belongs to the DEAD box helicase family
MAG.T21.18_00852	1286632.P278_19540	2.1e-64	252.3	Flavobacteriia	ppiC		5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217				ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	1HYBT@117743,4NDW4@976,COG0545@1,COG0545@2,COG0652@1,COG0652@2	NA|NA|NA	O	Peptidyl-prolyl cis-trans isomerase
MAG.T21.18_00853	1279009.ADICEAN_01347	1.2e-25	123.2	Cytophagia													Bacteria	2DZGZ@1,32VAD@2,47RS7@768503,4NSFP@976	NA|NA|NA		
MAG.T21.18_00854	760192.Halhy_3950	1.7e-43	182.6	Sphingobacteriia	plsC2												Bacteria	1IYKW@117747,4NNG7@976,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
MAG.T21.18_00855	760192.Halhy_6118	3.4e-32	145.2	Sphingobacteriia	cho	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342,ko:K03703,ko:K03763,ko:K05984	ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IQ4K@117747,4NEQX@976,COG0322@1,COG0322@2,COG0847@1,COG0847@2	NA|NA|NA	L	DNA polymerase III, epsilon subunit
MAG.T21.18_00857	485918.Cpin_6250	1.7e-38	166.0	Sphingobacteriia	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,2.7.7.87	ko:K00859,ko:K07566	ko00770,ko01100,map00770,map01100	M00120	R00130,R10463	RC00002,RC00078,RC00745	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016				Bacteria	1IS97@117747,4NQKS@976,COG0237@1,COG0237@2	NA|NA|NA	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAG.T21.18_00858	714943.Mucpa_4944	9.8e-23	112.8	Sphingobacteriia	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1ITXA@117747,4NUT4@976,COG1862@1,COG1862@2	NA|NA|NA	U	Preprotein translocase subunit YajC
MAG.T21.18_00859	1279009.ADICEAN_02163	6.7e-21	107.5	Cytophagia				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	47QE9@768503,4NRQ3@976,COG2885@1,COG2885@2	NA|NA|NA	M	Protein of unknown function (DUF1573)
MAG.T21.18_00860	755732.Fluta_3436	2.6e-68	265.8	Cryomorphaceae	nusB			ko:K03625					ko00000,ko03009,ko03021				Bacteria	1HXVJ@117743,2PAR4@246874,4NDVR@976,COG0781@1,COG0781@2	NA|NA|NA	K	NusB family
MAG.T21.18_00861	1120968.AUBX01000011_gene3013	1.1e-118	433.3	Cytophagia	ldh		1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130		R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000				Bacteria	47MHP@768503,4NF3I@976,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
MAG.T21.18_00862	1239962.C943_03080	1.3e-164	586.6	Cytophagia	mdlA			ko:K06147,ko:K18889	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21			Bacteria	47JPX@768503,4NDY6@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
MAG.T21.18_00864	927658.AJUM01000013_gene2634	1.5e-24	119.0	Marinilabiliaceae													Bacteria	2ASD9@1,2FS2B@200643,31HSR@2,3XK7R@558415,4NQ71@976	NA|NA|NA	S	Protein of unknown function (DUF3276)
MAG.T21.18_00865	1396141.BATP01000014_gene2733	2.7e-67	261.9	Verrucomicrobiae	ytkL												Bacteria	2IVIN@203494,46V9X@74201,COG2220@1,COG2220@2	NA|NA|NA	S	Beta-lactamase superfamily domain
MAG.T21.18_00866	1408433.JHXV01000010_gene614	1.8e-105	389.0	Cryomorphaceae	soj			ko:K03496					ko00000,ko03036,ko04812				Bacteria	1HXYG@117743,2PAED@246874,4NFEX@976,COG1192@1,COG1192@2	NA|NA|NA	D	PFAM CobQ CobB MinD ParA nucleotide binding domain
MAG.T21.18_00867	946077.W5A_12731	1.1e-76	293.5	Flavobacteriia	noc			ko:K03497					ko00000,ko03000,ko03036,ko04812				Bacteria	1HXJD@117743,4NFZ9@976,COG1475@1,COG1475@2	NA|NA|NA	K	Belongs to the ParB family
MAG.T21.18_00868	742725.HMPREF9450_01783	8.2e-30	137.1	Rikenellaceae													Bacteria	22UFW@171550,28PR3@1,2FTY0@200643,2ZCD0@2,4NMAF@976	NA|NA|NA		
MAG.T21.18_00870	1227266.HMPREF1551_00618	3.9e-59	235.0	Capnocytophaga	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1520	Bacteria	1EQHJ@1016,1HX1D@117743,4NDX2@976,COG0289@1,COG0289@2	NA|NA|NA	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAG.T21.18_00871	1454007.JAUG01000124_gene1073	1.8e-111	409.8	Sphingobacteriia	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1IRAK@117747,4NFTP@976,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
MAG.T21.18_00872	1347342.BN863_22540	2.6e-36	159.5	Flavobacteriia	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1HY4X@117743,4NFTP@976,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
MAG.T21.18_00874	926550.CLDAP_14660	3e-36	158.7	Chloroflexi	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818											Bacteria	2G7AT@200795,COG0494@1,COG0494@2	NA|NA|NA	L	PFAM NUDIX hydrolase
MAG.T21.18_00875	1239962.C943_02799	1.2e-90	341.7	Cytophagia													Bacteria	47MR3@768503,4NEVN@976,COG2114@1,COG2114@2,COG3292@1,COG3292@2	NA|NA|NA	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family
MAG.T21.18_00876	870187.Thini_2707	2.4e-08	67.8	Gammaproteobacteria				ko:K04043,ko:K07126	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1			Bacteria	1MWPA@1224,1RRKA@1236,COG0790@1,COG0790@2,COG4249@1,COG4249@2	NA|NA|NA	M	FOG TPR repeat SEL1 subfamily
MAG.T21.18_00878	1296415.JACC01000038_gene1898	2.2e-16	92.0	Aquimarina													Bacteria	1I3WS@117743,2CYW5@1,2YJE5@290174,32T50@2,4NS73@976	NA|NA|NA		
MAG.T21.18_00879	1121904.ARBP01000016_gene5290	2.1e-175	622.9	Cytophagia	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	47N4X@768503,4NEI1@976,COG2217@1,COG2217@2	NA|NA|NA	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC
MAG.T21.18_00880	290315.Clim_2241	1.3e-10	72.8	Bacteria													Bacteria	2CH44@1,33JG7@2	NA|NA|NA		
MAG.T21.18_00881	313596.RB2501_06115	3.4e-80	305.4	Flavobacteriia													Bacteria	1HXIA@117743,2ZA6T@2,4NGZ2@976,arCOG10456@1	NA|NA|NA		
MAG.T21.18_00883	491205.JARQ01000001_gene619	3.9e-72	278.1	Chryseobacterium	ric			ko:K07322					ko00000				Bacteria	1HXS5@117743,3ZQA0@59732,4NE9M@976,COG2846@1,COG2846@2	NA|NA|NA	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MAG.T21.18_00884	1484460.JSWG01000008_gene1892	9.8e-103	380.9	Flavobacteriia			1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110		R02394	RC01983	ko00000,ko00001,ko01000				Bacteria	1HZIA@117743,4NE3N@976,COG2132@1,COG2132@2	NA|NA|NA	Q	Multicopper oxidase
MAG.T21.18_00885	760192.Halhy_5491	2.3e-69	269.6	Sphingobacteriia													Bacteria	1IRVC@117747,4NHY4@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_00886	866536.Belba_1980	8.8e-29	133.7	Cytophagia													Bacteria	47XRG@768503,4NHY4@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_00889	929556.Solca_4202	2e-77	295.8	Sphingobacteriia													Bacteria	1IR1D@117747,4NF6D@976,COG2227@1,COG2227@2	NA|NA|NA	H	Thiopurine S-methyltransferase (TPMT)
MAG.T21.18_00890	1122176.KB903552_gene3711	5e-118	431.4	Sphingobacteriia													Bacteria	1IRTW@117747,4NGND@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.18_00891	1408433.JHXV01000005_gene2405	6.5e-35	155.2	Cryomorphaceae													Bacteria	1ICR5@117743,2A19C@1,2PBUY@246874,30PFU@2,4PC1I@976	NA|NA|NA	S	Glycosyltransferase family 87
MAG.T21.18_00893	1122604.JONR01000001_gene1981	3.1e-31	141.4	Xanthomonadales				ko:K06893					ko00000				Bacteria	1MZ0P@1224,1S7Z4@1236,1X7MA@135614,COG3631@1,COG3631@2	NA|NA|NA	S	SnoaL-like domain
MAG.T21.18_00894	118168.MC7420_3750	1.9e-49	203.4	Oscillatoriales			3.2.1.156,3.4.21.10	ko:K01317,ko:K15531					ko00000,ko01000,ko01002,ko04131		GH8		Bacteria	1GBUS@1117,1HEVI@1150,COG1572@1,COG1572@2,COG2931@1,COG2931@2,COG3291@1,COG3291@2	NA|NA|NA	Q	Haemolysin-type calcium-binding repeat (2 copies)
MAG.T21.18_00895	925409.KI911562_gene2369	3.7e-169	601.7	Bacteroidetes													Bacteria	4NGUB@976,COG0308@1,COG0308@2	NA|NA|NA	E	peptidase M1
MAG.T21.18_00896	1121957.ATVL01000012_gene775	1.3e-47	197.2	Cytophagia													Bacteria	47Q1W@768503,4PKGZ@976,COG3386@1,COG3386@2	NA|NA|NA	G	phospholipase Carboxylesterase
MAG.T21.18_00898	1121899.Q764_11825	6.6e-203	714.1	Flavobacterium			3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110		GH20		Bacteria	1HXU1@117743,2NSHE@237,4NE08@976,COG3525@1,COG3525@2	NA|NA|NA	G	Pfam Glycosyl hydrolase family 20, catalytic domain
MAG.T21.18_00899	468059.AUHA01000002_gene828	2.2e-46	192.2	Sphingobacteriia	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02959	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1IRXR@117747,4NNY8@976,COG0228@1,COG0228@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS16 family
MAG.T21.18_00900	1007103.AFHW01000017_gene5757	3.2e-18	98.6	Paenibacillaceae													Bacteria	1TYVP@1239,26YIC@186822,4I0UE@91061,COG4430@1,COG4430@2	NA|NA|NA	S	Domain of unknown function (DUF1905)
MAG.T21.18_00901	1166018.FAES_0900	6.7e-24	116.7	Cytophagia	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K03113	ko03013,map03013				ko00000,ko00001,ko03012				Bacteria	47R38@768503,4NS6M@976,COG0023@1,COG0023@2	NA|NA|NA	J	PFAM translation initiation factor SUI1
MAG.T21.18_00902	313606.M23134_00633	4.9e-30	138.7	Cytophagia													Bacteria	28MS7@1,2ZB0M@2,47JQ9@768503,4NHCQ@976	NA|NA|NA		
MAG.T21.18_00903	1313301.AUGC01000017_gene822	2e-134	485.7	Bacteroidetes	stsA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576	2.6.1.109	ko:K19715			R11395	RC00160	ko00000,ko01000,ko01005				Bacteria	4NG9W@976,COG0399@1,COG0399@2	NA|NA|NA	E	Belongs to the DegT DnrJ EryC1 family
MAG.T21.18_00904	1382306.JNIM01000001_gene2893	9.3e-43	181.0	Chloroflexi	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802			R10938	RC03309	ko00000,ko01000				Bacteria	2G8E6@200795,COG4948@1,COG4948@2	NA|NA|NA	M	PFAM Mandelate racemase muconate lactonizing protein
MAG.T21.18_00905	1122176.KB903551_gene4219	2e-50	206.5	Bacteria	glsA		3.5.1.2	ko:K01425,ko:K13652	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230		R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000,ko03000				Bacteria	COG3832@1,COG3832@2,COG4978@1,COG4978@2	NA|NA|NA	J	glyoxalase III activity
MAG.T21.18_00906	1453500.AT05_08105	3.1e-24	118.6	Bacteroidetes													Bacteria	2CC29@1,32RUM@2,4NS83@976	NA|NA|NA		
MAG.T21.18_00907	1107311.Q767_14510	1.4e-79	302.8	Flavobacterium	yugP			ko:K06973					ko00000				Bacteria	1HXAU@117743,2NSBY@237,4NDWG@976,COG2738@1,COG2738@2	NA|NA|NA	S	membrane
MAG.T21.18_00908	873517.HMPREF1977_0976	2e-152	545.4	Capnocytophaga	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464		ko:K06942					ko00000,ko03009				Bacteria	1ERCZ@1016,1HWMK@117743,4NF7N@976,COG0012@1,COG0012@2	NA|NA|NA	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAG.T21.18_00909	743722.Sph21_3915	2.2e-117	428.7	Sphingobacteriia	tktA		2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPAD@117747,4NDWK@976,COG3959@1,COG3959@2	NA|NA|NA	G	Transketolase
MAG.T21.18_00910	926562.Oweho_1341	2.6e-107	396.0	Cryomorphaceae	ywmD			ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	1I5HE@117743,2PAI7@246874,4NJF1@976,COG2304@1,COG2304@2	NA|NA|NA	S	PFAM von Willebrand factor type A domain
MAG.T21.18_00911	929556.Solca_0536	9.5e-135	486.5	Sphingobacteriia	tktC		2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000				Bacteria	1IR3A@117747,4NEI8@976,COG3958@1,COG3958@2	NA|NA|NA	G	Transketolase
MAG.T21.18_00912	929703.KE386491_gene799	1.7e-52	212.6	Cytophagia				ko:K03088					ko00000,ko03021				Bacteria	47N5B@768503,4NMC0@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.18_00914	1123234.AUKI01000011_gene1397	7e-12	77.4	Flavobacteriia													Bacteria	1I5A4@117743,2DPE1@1,331PZ@2,4NV5C@976	NA|NA|NA		
MAG.T21.18_00915	1237149.C900_00593	9.1e-127	460.3	Cytophagia	argD		2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	47JJU@768503,4NFMC@976,COG4992@1,COG4992@2	NA|NA|NA	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.18_00916	755732.Fluta_0707	2.4e-85	323.9	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1HZ7Y@117743,2PBDM@246874,4NGRJ@976,COG3291@1,COG3291@2,COG5549@1,COG5549@2	NA|NA|NA	O	PFAM Pregnancy-associated plasma protein-A
MAG.T21.18_00917	313596.RB2501_15394	8.2e-71	273.9	Flavobacteriia	nth		4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1HWQK@117743,4NE7K@976,COG0177@1,COG0177@2	NA|NA|NA	L	TIGRFAM TIGR02757 family protein
MAG.T21.18_00918	746697.Aeqsu_2655	1.3e-91	342.8	Flavobacteriia													Bacteria	1HXDZ@117743,4NEAI@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	reductase
MAG.T21.18_00919	1004149.AFOE01000041_gene1129	1.4e-200	706.1	Flavobacteriia	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1HY2B@117743,4NE7Q@976,COG0018@1,COG0018@2	NA|NA|NA	J	Arginyl-tRNA synthetase
MAG.T21.18_00920	700598.Niako_0983	2.4e-66	259.2	Sphingobacteriia													Bacteria	1IQ05@117747,4NFG3@976,COG4874@1,COG4874@2	NA|NA|NA	S	Amidinotransferase
MAG.T21.18_00921	45351.EDO26796	4.1e-74	285.0	Metazoa			3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000				Metazoa	38CCH@33154,3BCCT@33208,COG0010@1,KOG2965@2759	NA|NA|NA	E	arginase activity
MAG.T21.18_00922	755732.Fluta_0518	2.8e-19	102.4	Cryomorphaceae													Bacteria	1ICSJ@117743,2A8FU@1,2PC02@246874,30XHS@2,4PAYV@976	NA|NA|NA		
MAG.T21.18_00923	926562.Oweho_0714	9.1e-249	866.7	Cryomorphaceae	ftsK			ko:K03466					ko00000,ko03036	3.A.12			Bacteria	1HXBM@117743,2PAJ7@246874,4NE86@976,COG1674@1,COG1674@2	NA|NA|NA	D	Ftsk_gamma
MAG.T21.18_00924	1121887.AUDK01000018_gene3210	3e-46	193.4	Flavobacterium	coiA		3.6.4.12	ko:K03657,ko:K06198	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1IDH0@117743,2NYE5@237,4PC86@976,COG4469@1,COG4469@2	NA|NA|NA	S	Competence protein
MAG.T21.18_00927	1121904.ARBP01000005_gene4626	1.1e-34	152.9	Cytophagia													Bacteria	29E7I@1,3015I@2,47T83@768503,4NNFG@976	NA|NA|NA	S	Protein of unknown function (DUF1761)
MAG.T21.18_00928	762903.Pedsa_2785	1.2e-10	73.9	Sphingobacteriia													Bacteria	1IU32@117747,2BBPA@1,3257C@2,4NRAR@976	NA|NA|NA	S	Protein of unknown function (DUF3575)
MAG.T21.18_00929	1150600.ADIARSV_0200	1.5e-36	159.5	Sphingobacteriia				ko:K04750					ko00000				Bacteria	1ISV0@117747,4NQD7@976,COG2764@1,COG2764@2	NA|NA|NA	S	PFAM 3-demethylubiquinone-9 3-methyltransferase
MAG.T21.18_00930	1408433.JHXV01000009_gene1250	3.2e-19	102.8	Bacteroidetes													Bacteria	4PP7N@976,COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_00932	1049564.TevJSym_ac01880	6e-35	154.8	Bacteria	nucH		3.1.3.5	ko:K01081,ko:K07004	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	COG2374@1,COG2374@2	NA|NA|NA		
MAG.T21.18_00933	1082933.MEA186_10410	2e-14	85.5	Phyllobacteriaceae				ko:K07343					ko00000				Bacteria	1NAYG@1224,2UIGT@28211,43M3V@69277,COG3070@1,COG3070@2	NA|NA|NA	K	TfoX N-terminal domain
MAG.T21.18_00934	1408433.JHXV01000002_gene292	7.8e-20	104.4	Cryomorphaceae													Bacteria	1IMS2@117743,2A607@1,2PBUU@246874,30USF@2,4PFQT@976	NA|NA|NA		
MAG.T21.18_00935	585531.HMPREF0063_10252	1.6e-12	79.7	Propionibacteriales	tadA		3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19	ko:K01485,ko:K01563,ko:K04075,ko:K11991	ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120		R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223	RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016				Bacteria	2IM3Z@201174,4DQP2@85009,COG0590@1,COG0590@2	NA|NA|NA	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAG.T21.18_00937	234267.Acid_5969	8.3e-145	520.4	Acidobacteria	rhbB		4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	3Y365@57723,COG0076@1,COG0076@2	NA|NA|NA	E	Pyridoxal-dependent decarboxylase conserved domain
MAG.T21.18_00938	269798.CHU_1750	5.3e-72	277.7	Cytophagia			1.16.3.1	ko:K03594	ko00860,map00860		R00078	RC02758	ko00000,ko00001,ko01000				Bacteria	47VXD@768503,4NKSU@976,COG1633@1,COG1633@2	NA|NA|NA	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MAG.T21.18_00940	1121859.KB890739_gene2695	1.5e-40	173.3	Cytophagia													Bacteria	47QTA@768503,4NRJJ@976,COG4185@1,COG4185@2	NA|NA|NA	S	zeta toxin
MAG.T21.18_00941	192952.MM_2977	1.7e-21	109.8	Archaea													Archaea	COG0457@1,arCOG11981@2157	NA|NA|NA	S	peptidyl-tyrosine sulfation
MAG.T21.18_00942	1124780.ANNU01000018_gene1636	1.3e-250	872.5	Cytophagia	bfmBA		1.2.4.1,1.2.4.4	ko:K00161,ko:K00167,ko:K11381,ko:K21416,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47KFY@768503,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2	NA|NA|NA	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit
MAG.T21.18_00943	251229.Chro_0517	1.3e-30	140.6	Pleurocapsales													Bacteria	1G4JF@1117,3VME5@52604,COG0463@1,COG0463@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.18_00944	426117.M446_0944	8.7e-53	213.8	Bacteria			2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	COG2227@1,COG2227@2	NA|NA|NA	H	3-demethylubiquinone-9 3-O-methyltransferase activity
MAG.T21.18_00946	385682.AFSL01000073_gene1395	3.3e-102	379.4	Marinilabiliaceae				ko:K01138					ko00000,ko01000				Bacteria	2FNHQ@200643,3XKJM@558415,4NIAA@976,COG1368@1,COG1368@2	NA|NA|NA	M	Sulfatase
MAG.T21.18_00947	926562.Oweho_1125	1.5e-41	176.8	Cryomorphaceae	dagK												Bacteria	1HZF4@117743,2PAU5@246874,4NJWB@976,COG1597@1,COG1597@2	NA|NA|NA	I	Diacylglycerol kinase catalytic domain (presumed)
MAG.T21.18_00948	1341155.FSS13T_00640	1.1e-140	507.3	Flavobacterium													Bacteria	1IJEU@117743,2NURX@237,4PKTY@976,COG3291@1,COG3291@2	NA|NA|NA	S	ASPIC and UnbV
MAG.T21.18_00949	1296415.JACC01000036_gene1186	1.1e-81	310.1	Aquimarina	motB			ko:K02557	ko02030,ko02040,map02030,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	1HY7B@117743,2YHRJ@290174,4NF2Y@976,COG1360@1,COG1360@2	NA|NA|NA	N	OmpA family
MAG.T21.18_00950	313606.M23134_01922	3.5e-36	158.3	Cytophagia													Bacteria	47XMK@768503,4NN09@976,COG0664@1,COG0664@2	NA|NA|NA	T	Cyclic nucleotide-binding domain
MAG.T21.18_00951	700598.Niako_7037	2.3e-24	119.0	Sphingobacteriia													Bacteria	1ITXI@117747,4NP2C@976,COG2318@1,COG2318@2	NA|NA|NA	S	DinB superfamily
MAG.T21.18_00952	153721.MYP_607	7.5e-154	550.4	Cytophagia	phoH			ko:K07175					ko00000				Bacteria	47M94@768503,4NDUI@976,COG1875@1,COG1875@2	NA|NA|NA	T	PIN domain
MAG.T21.18_00953	755732.Fluta_1314	2.1e-48	200.7	Bacteria													Bacteria	COG1409@1,COG1409@2	NA|NA|NA	S	acid phosphatase activity
MAG.T21.18_00954	391587.KAOT1_08433	7.4e-92	344.7	Flavobacteriia													Bacteria	1HX9D@117743,4NF0B@976,COG2133@1,COG2133@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.18_00955	471854.Dfer_5122	1.4e-210	739.2	Cytophagia	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02837,ko:K07133					ko00000,ko03012				Bacteria	47JQE@768503,4NFEZ@976,COG4108@1,COG4108@2	NA|NA|NA	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAG.T21.18_00956	1408433.JHXV01000012_gene3988	1.9e-97	363.2	Cryomorphaceae				ko:K12057					ko00000,ko02044	3.A.7.11.1			Bacteria	1IMQS@117743,2PBFS@246874,4NHEC@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Domain of unknown function (DUF5106)
MAG.T21.18_00957	1408433.JHXV01000001_gene1064	1.9e-10	72.8	Cryomorphaceae													Bacteria	1ICRX@117743,29BEQ@1,2PBXT@246874,2ZYD2@2,4PD0R@976	NA|NA|NA		
MAG.T21.18_00958	1408433.JHXV01000010_gene536	2.4e-124	452.2	Cryomorphaceae	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757		ko:K00754					ko00000,ko01000		GT4		Bacteria	1HWYY@117743,2PA98@246874,4NFPA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferase 4-like
MAG.T21.18_00959	1408433.JHXV01000002_gene300	2e-16	91.3	Cryomorphaceae													Bacteria	1I51R@117743,2E5GR@1,2PC1K@246874,3308C@2,4NUPC@976	NA|NA|NA		
MAG.T21.18_00960	1120951.AUBG01000014_gene3203	1.8e-22	112.1	Flavobacteriia	M1-746												Bacteria	1I49Y@117743,4NUVP@976,COG4818@1,COG4818@2	NA|NA|NA	S	PFAM Chloroplast import component protein (Tic20)
MAG.T21.18_00961	929556.Solca_2878	3.3e-119	434.9	Sphingobacteriia	ftsY			ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7			Bacteria	1IPD8@117747,4NE9Z@976,COG0552@1,COG0552@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAG.T21.18_00963	1515615.HQ41_07520	7.3e-23	112.5	Porphyromonadaceae	rpmG			ko:K02913	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	22YNB@171551,2FTST@200643,4NURM@976,COG0267@1,COG0267@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL33 family
MAG.T21.18_00964	1461577.CCMH01000045_gene845	3e-21	107.5	Flavobacteriia	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02902	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I3YG@117743,4NS7Q@976,COG0227@1,COG0227@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL28 family
MAG.T21.18_00965	760192.Halhy_0377	4.9e-38	164.9	Sphingobacteriia				ko:K06219					ko00000				Bacteria	1IYVG@117747,4PNUQ@976,COG2227@1,COG2227@2	NA|NA|NA	H	PFAM Methyltransferase type 11
MAG.T21.18_00966	761193.Runsl_5365	7.7e-108	397.5	Cytophagia	cinA		3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760		R02322	RC00100	ko00000,ko00001,ko01000				Bacteria	47JN4@768503,4NDVV@976,COG1058@1,COG1058@2,COG1546@1,COG1546@2	NA|NA|NA	S	CinA-like protein
MAG.T21.18_00967	655815.ZPR_2377	4.3e-255	887.9	Flavobacteriia													Bacteria	1HYCC@117743,4NDXM@976,COG0612@1,COG0612@2	NA|NA|NA	S	Belongs to the peptidase M16 family
MAG.T21.18_00968	402612.FP0742	3.8e-63	248.1	Flavobacterium	miaE			ko:K06169					ko00000,ko01000,ko03016				Bacteria	1HYKM@117743,2NTPY@237,4NFY4@976,COG4445@1,COG4445@2	NA|NA|NA	FJ	tRNA hydroxylase
MAG.T21.18_00969	926562.Oweho_1060	9.5e-44	183.7	Cryomorphaceae													Bacteria	1IJP8@117743,2PB5D@246874,4PKF6@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_00970	1408813.AYMG01000023_gene2169	1.4e-44	186.0	Sphingobacteriia	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380	Bacteria	1ISBW@117747,4NNUC@976,COG0054@1,COG0054@2	NA|NA|NA	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MAG.T21.18_00971	1185876.BN8_05492	3.7e-08	65.5	Cytophagia													Bacteria	47Q6V@768503,4NMX1@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.18_00972	153721.MYP_2423	5.2e-68	264.2	Cytophagia	yjdF			ko:K08984					ko00000				Bacteria	47RI0@768503,4NMNV@976,COG3647@1,COG3647@2	NA|NA|NA	S	Predicted membrane protein (DUF2238)
MAG.T21.18_00973	504472.Slin_4983	6.5e-08	64.7	Cytophagia													Bacteria	47Q6V@768503,4NMX1@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.18_00974	1121918.ARWE01000001_gene57	2.7e-35	155.2	Bacteria													Bacteria	COG2050@1,COG2050@2	NA|NA|NA	Q	thiolester hydrolase activity
MAG.T21.18_00975	237368.SCABRO_03886	1.2e-16	92.8	Planctomycetes													Bacteria	2CCSR@1,2J1M5@203682,32RWC@2	NA|NA|NA	S	23S rRNA-intervening sequence protein
MAG.T21.18_00976	1223410.KN050846_gene2689	5.8e-44	183.7	Flavobacteriia	XK27_03185			ko:K16785	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1I23U@117743,4NNW2@976,COG4696@1,COG4696@2	NA|NA|NA	S	protein conserved in bacteria
MAG.T21.18_00977	509635.N824_03585	2.7e-135	488.4	Sphingobacteriia	moxR			ko:K03924					ko00000,ko01000				Bacteria	1IPXJ@117747,4NDVZ@976,COG0714@1,COG0714@2	NA|NA|NA	S	PFAM ATPase family associated with various cellular activities (AAA)
MAG.T21.18_00978	485917.Phep_1479	5.1e-101	374.4	Sphingobacteriia		GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944											Bacteria	1IR6K@117747,4NE2N@976,COG1721@1,COG1721@2	NA|NA|NA	S	protein (some members contain a von Willebrand factor type A (vWA) domain)
MAG.T21.18_00979	1123400.KB904765_gene1396	1.2e-35	158.7	Proteobacteria													Bacteria	1QUSE@1224,COG0823@1,COG0823@2,COG1361@1,COG1361@2,COG2706@1,COG2706@2,COG2834@1,COG2834@2,COG3291@1,COG3291@2,COG5384@1,COG5384@2	NA|NA|NA	G	PFAM FecR protein
MAG.T21.18_00982	755732.Fluta_0946	9.3e-122	443.4	Cryomorphaceae	moxR			ko:K03924					ko00000,ko01000				Bacteria	1HXA1@117743,2PA5W@246874,4NDVZ@976,COG0714@1,COG0714@2	NA|NA|NA	S	PFAM ATPase family associated with various cellular activities (AAA)
MAG.T21.18_00983	926562.Oweho_0145	9e-94	350.9	Cryomorphaceae	surA		5.2.1.8	ko:K03771					ko00000,ko01000,ko03110				Bacteria	1HXTE@117743,2PA5V@246874,4NEW0@976,COG0760@1,COG0760@2	NA|NA|NA	M	PPIC-type PPIASE domain
MAG.T21.18_00984	1168034.FH5T_00400	5.3e-28	131.7	Bacteroidia	epsD		5.2.1.8	ko:K03771					ko00000,ko01000,ko03110				Bacteria	2FMWD@200643,4NG2P@976,COG0760@1,COG0760@2	NA|NA|NA	O	COG NOG23400 non supervised orthologous group
MAG.T21.18_00985	755732.Fluta_0944	5.9e-132	478.4	Cryomorphaceae			5.2.1.8	ko:K03769,ko:K03771					ko00000,ko01000,ko03110				Bacteria	1HXI1@117743,2PAM4@246874,4NGIR@976,COG0760@1,COG0760@2	NA|NA|NA	M	PPIC-type PPIASE domain
MAG.T21.18_00986	1408473.JHXO01000008_gene2881	2.1e-57	229.2	Bacteroidia	djlA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944		ko:K04082,ko:K05801,ko:K11159					ko00000,ko03029,ko03110				Bacteria	2FQ12@200643,4NF1B@976,COG1076@1,COG1076@2	NA|NA|NA	O	DnaJ domain protein
MAG.T21.18_00987	385682.AFSL01000002_gene1869	1.3e-36	160.2	Marinilabiliaceae	Z012_08980		3.4.24.3	ko:K01387,ko:K06872					ko00000,ko01000,ko01002,ko02042				Bacteria	2FN0H@200643,3XJPS@558415,4NF4P@976,COG1512@1,COG1512@2	NA|NA|NA	S	TPM domain
MAG.T21.18_00988	385682.AFSL01000002_gene1868	1.2e-34	152.9	Marinilabiliaceae	Z012_08985			ko:K08988					ko00000				Bacteria	2FTHS@200643,3XK37@558415,4NQIT@976,COG3762@1,COG3762@2	NA|NA|NA	S	TPM domain
MAG.T21.18_00989	1237149.C900_00796	1.3e-44	186.4	Cytophagia	lemA			ko:K03744					ko00000				Bacteria	47JGT@768503,4NMD3@976,COG1704@1,COG1704@2	NA|NA|NA	S	PFAM LemA family
MAG.T21.18_00990	1227739.Hsw_3091	4.4e-24	119.0	Bacteroidetes													Bacteria	2DX8D@1,343UE@2,4P6Q1@976	NA|NA|NA		
MAG.T21.18_00991	485918.Cpin_2225	7e-38	164.1	Sphingobacteriia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1J0MG@117747,4PN7E@976,COG1629@1,COG4771@2	NA|NA|NA	P	CarboxypepD_reg-like domain
MAG.T21.18_00992	1408433.JHXV01000029_gene3080	1.5e-163	582.8	Cryomorphaceae	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022				Bacteria	1HXC5@117743,2PAKV@246874,4NEJ3@976,COG0764@1,COG0764@2,COG0774@1,COG0774@2	NA|NA|NA	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
MAG.T21.18_00993	1279009.ADICEAN_04067	1.7e-57	229.6	Cytophagia	lpxA		2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	47JJC@768503,4NEBA@976,COG1043@1,COG1043@2	NA|NA|NA	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAG.T21.18_00994	760192.Halhy_4707	1.4e-41	176.4	Sphingobacteriia	ccmA		3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107			Bacteria	1IS33@117747,4NN9G@976,COG1131@1,COG1131@2	NA|NA|NA	V	ABC transporter
MAG.T21.18_00995	929556.Solca_3194	6.9e-64	250.4	Sphingobacteriia													Bacteria	1IPH6@117747,28M4Q@1,2ZAIK@2,4NJC3@976	NA|NA|NA		
MAG.T21.18_00996	1267211.KI669560_gene1570	2e-28	132.1	Sphingobacteriia			3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1ISSM@117747,4NR5C@976,COG1051@1,COG1051@2	NA|NA|NA	F	pfam nudix
MAG.T21.18_00997	1408433.JHXV01000002_gene316	2.4e-23	115.2	Cryomorphaceae													Bacteria	1IGIK@117743,2PB7C@246874,4PHJK@976,COG3427@1,COG3427@2	NA|NA|NA	E	oxidoreductase activity, acting on CH-OH group of donors
MAG.T21.18_00999	926562.Oweho_1492	7e-179	634.0	Cryomorphaceae	msbA2			ko:K06147,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1HYJM@117743,2PAJ2@246874,4PKCT@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC-type multidrug transport system ATPase and permease
MAG.T21.18_01000	504472.Slin_4081	7.1e-59	233.8	Cytophagia	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501					ko00000,ko01000,ko03009,ko03036				Bacteria	47KEA@768503,4NEJG@976,COG0357@1,COG0357@2	NA|NA|NA	J	Specifically methylates the N7 position of a guanine in 16S rRNA
MAG.T21.18_01001	886379.AEWI01000030_gene300	2.6e-69	268.5	Marinilabiliaceae				ko:K03088					ko00000,ko03021				Bacteria	2FRYA@200643,3XJ8R@558415,4NIRG@976,COG1595@1,COG1595@2	NA|NA|NA	K	ECF sigma factor
MAG.T21.18_01002	485918.Cpin_6919	3e-60	239.2	Sphingobacteriia				ko:K20541					ko00000,ko02000	4.D.3.1.6			Bacteria	1IQGQ@117747,4NESG@976,COG1215@1,COG1215@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.18_01003	313596.RB2501_12357	4.9e-154	550.8	Flavobacteriia	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773			R03789,R10209	RC00063	ko00000,ko01000,ko03016				Bacteria	1HXAZ@117743,4NE15@976,COG0343@1,COG0343@2	NA|NA|NA	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MAG.T21.18_01004	1453500.AT05_02940	2.1e-82	312.8	Flavobacteriia	lptG	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K11720	ko02010,map02010	M00320			ko00000,ko00001,ko00002,ko02000	1.B.42.1		iSSON_1240.SSON_4447	Bacteria	1HWXZ@117743,4NF8Y@976,COG0795@1,COG0795@2	NA|NA|NA	S	Permease, YjgP YjgQ family
MAG.T21.18_01005	1121015.N789_02375	6.6e-43	181.0	Xanthomonadales				ko:K07090					ko00000				Bacteria	1RD5A@1224,1S6M1@1236,1XAJC@135614,COG0730@1,COG0730@2	NA|NA|NA	S	Sulfite exporter TauE/SafE
MAG.T21.18_01006	742725.HMPREF9450_00198	6.5e-30	137.1	Rikenellaceae	queD		4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	22UI1@171550,2FU4Q@200643,4NM8H@976,COG0720@1,COG0720@2	NA|NA|NA	H	6-pyruvoyl tetrahydropterin synthase
MAG.T21.18_01008	1121957.ATVL01000007_gene2399	2.6e-07	62.4	Cytophagia													Bacteria	47YQ3@768503,4NNAV@976,COG2373@1,COG2373@2,COG3291@1,COG3291@2,COG3391@1,COG3391@2,COG4719@1,COG4719@2	NA|NA|NA	G	TIGRFAM conserved repeat domain
MAG.T21.18_01009	313596.RB2501_10287	4.1e-50	204.9	Flavobacteriia													Bacteria	1HZAP@117743,28K10@1,2Z9QW@2,4NF8J@976	NA|NA|NA	S	Domain of unknown function (DUF4918)
MAG.T21.18_01010	313606.M23134_01067	1.5e-36	159.5	Bacteroidetes				ko:K03088					ko00000,ko03021				Bacteria	4NXBB@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.18_01011	194867.ALBQ01000001_gene2952	1.1e-07	64.7	Sphingomonadales													Bacteria	1N374@1224,2K1A2@204457,2UDAB@28211,COG3595@1,COG3595@2	NA|NA|NA	S	Putative auto-transporter adhesin, head GIN domain
MAG.T21.18_01014	755732.Fluta_0036	2e-51	209.5	Cryomorphaceae	yneA	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496		ko:K06194					ko00000	1.A.34.1.2			Bacteria	1HZ6D@117743,2PBE5@246874,4NGHH@976,COG0739@1,COG0739@2,COG1388@1,COG1388@2	NA|NA|NA	M	Lysin motif
MAG.T21.18_01015	709991.Odosp_2289	1.2e-154	553.5	Porphyromonadaceae													Bacteria	22XTQ@171551,2FSAD@200643,4NF25@976,COG0204@1,COG0204@2,COG3176@1,COG3176@2	NA|NA|NA	I	Phosphate acyltransferases
MAG.T21.18_01019	1453500.AT05_06150	1e-77	296.6	Flavobacteriia													Bacteria	1HWZ6@117743,4NG7D@976,COG0745@1,COG0745@2	NA|NA|NA	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.18_01021	1197477.IA57_03830	1.9e-127	462.6	Flavobacteriia	dcm		2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	1HZAK@117743,4NG9A@976,COG0270@1,COG0270@2	NA|NA|NA	H	cytosine-specific methyltransferase
MAG.T21.18_01022	700598.Niako_1031	2.8e-70	271.6	Sphingobacteriia	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K12267					ko00000,ko01000				Bacteria	1IS23@117747,4NMAJ@976,COG0225@1,COG0225@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAG.T21.18_01023	1392498.JQLH01000001_gene2621	1.8e-23	115.5	Maribacter	MA20_19755												Bacteria	1I31N@117743,2PIMS@252356,4NQ7W@976,COG5349@1,COG5349@2	NA|NA|NA	S	Protein of unknown function (DUF983)
MAG.T21.18_01024	1121875.KB907550_gene772	8.4e-16	90.9	Flavobacteriia													Bacteria	1IJN7@117743,4PM90@976,COG0500@1,COG0500@2	NA|NA|NA	Q	Protein of unknown function (DUF1698)
MAG.T21.18_01025	1408433.JHXV01000021_gene1640	2.4e-147	528.9	Cryomorphaceae	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707			R10649	RC00003,RC03221	ko00000,ko01000,ko03016				Bacteria	1HWYI@117743,2PAD9@246874,4NE0R@976,COG0621@1,COG0621@2	NA|NA|NA	J	Uncharacterized protein family UPF0004
MAG.T21.18_01026	1123248.KB893359_gene2055	2.4e-87	329.3	Sphingobacteriia													Bacteria	1INRB@117747,4NGSG@976,COG0682@1,COG0682@2	NA|NA|NA	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAG.T21.18_01027	926549.KI421517_gene1121	2.1e-74	285.8	Cytophagia	suhB		3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	47K2K@768503,4NI6D@976,COG0483@1,COG0483@2	NA|NA|NA	G	Inositol monophosphatase
MAG.T21.18_01028	1124780.ANNU01000042_gene619	4.7e-144	518.1	Cytophagia													Bacteria	47KNW@768503,4NEF3@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.18_01029	1287488.HMPREF0671_11260	8.5e-60	236.9	Bacteroidia	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K06187	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	2FM1C@200643,4NEWI@976,COG0353@1,COG0353@2	NA|NA|NA	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAG.T21.18_01030	1408433.JHXV01000002_gene372	4.7e-141	508.4	Cryomorphaceae	wbbL			ko:K07011					ko00000				Bacteria	1HWKX@117743,2PA5Z@246874,4NFW5@976,COG1216@1,COG1216@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.18_01031	1453500.AT05_03720	3.3e-141	508.4	Flavobacteriia	bfmBB		2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1HWW8@117743,4NED0@976,COG0508@1,COG0508@2	NA|NA|NA	C	dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MAG.T21.18_01032	1408433.JHXV01000026_gene3026	4.9e-126	458.8	Cryomorphaceae				ko:K02057		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1IE72@117743,2PBDD@246874,4P15I@976,COG0419@1,COG0419@2,COG0823@1,COG0823@2	NA|NA|NA	U	WD40-like Beta Propeller Repeat
MAG.T21.18_01033	272559.BF9343_2769	6.6e-62	244.2	Bacteroidaceae	dnaQ		2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2FMQF@200643,4AM2F@815,4NE82@976,COG0847@1,COG0847@2	NA|NA|NA	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
MAG.T21.18_01034	1237149.C900_02933	8.4e-45	188.7	Cytophagia													Bacteria	47QDQ@768503,4NF45@976,COG0457@1,COG0457@2,COG2972@1,COG2972@2	NA|NA|NA	T	signal transduction protein with a C-terminal ATPase domain
MAG.T21.18_01035	388413.ALPR1_10445	5.8e-44	184.5	Cytophagia				ko:K02477					ko00000,ko02022				Bacteria	47PTI@768503,4NFPV@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator of the LytR AlgR family
MAG.T21.18_01036	1191523.MROS_1311	1.4e-10	74.3	Bacteria			3.1.3.1	ko:K01113,ko:K20276	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	COG1520@1,COG1520@2,COG4932@1,COG4932@2	NA|NA|NA	S	amino acid activation for nonribosomal peptide biosynthetic process
MAG.T21.18_01037	661478.OP10G_3050	9.5e-51	206.8	Bacteria	ycgM												Bacteria	COG0179@1,COG0179@2	NA|NA|NA	Q	Fumarylacetoacetate (FAA) hydrolase
MAG.T21.18_01038	1313301.AUGC01000003_gene2099	7.9e-125	453.4	Bacteroidetes	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	4NENN@976,COG2877@1,COG2877@2	NA|NA|NA	M	Belongs to the KdsA family
MAG.T21.18_01039	1313301.AUGC01000003_gene2100	3.1e-123	448.4	Bacteroidetes	tal		1.1.1.42,1.3.1.85,2.2.1.2	ko:K00031,ko:K00616,ko:K14446	ko00020,ko00030,ko00480,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00030,map00480,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00004,M00007,M00009,M00010,M00173,M00373,M00740	R00267,R00268,R01827,R01899,R09291	RC00001,RC00084,RC00114,RC00439,RC00604,RC00626,RC02481,RC02801	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	4NIUX@976,COG0176@1,COG0176@2,COG2905@1,COG2905@2	NA|NA|NA	GT	Transaldolase/Fructose-6-phosphate aldolase
MAG.T21.18_01040	1123277.KB893239_gene1226	4.2e-47	194.9	Cytophagia	neuA		2.7.7.43,3.1.3.45	ko:K00983,ko:K03270	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	47PAE@768503,4NMFZ@976,COG1778@1,COG1778@2	NA|NA|NA	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MAG.T21.18_01041	414684.RC1_2049	1.2e-17	96.3	Rhodospirillales													Bacteria	1N6RE@1224,2JUF3@204441,2UFAH@28211,COG4704@1,COG4704@2	NA|NA|NA	S	Uncharacterized protein conserved in bacteria (DUF2141)
MAG.T21.18_01042	266117.Rxyl_1076	6e-35	154.1	Rubrobacteria	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684			R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000				Bacteria	2IFT7@201174,4CQQI@84995,COG2360@1,COG2360@2	NA|NA|NA	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MAG.T21.18_01043	1168034.FH5T_03220	2.9e-107	396.0	Bacteroidia	aprN												Bacteria	2FNT5@200643,4NEIJ@976,COG1404@1,COG1404@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_01044	755732.Fluta_4037	3e-18	99.0	Cryomorphaceae													Bacteria	1ICRH@117743,298K1@1,2PBW9@246874,32FY8@2,4PK0P@976	NA|NA|NA		
MAG.T21.18_01045	714943.Mucpa_5190	3e-129	468.4	Sphingobacteriia	mnmA		2.8.1.13	ko:K00566	ko04122,map04122		R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016				Bacteria	1IR3X@117747,4NFXZ@976,COG0482@1,COG0482@2	NA|NA|NA	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAG.T21.18_01046	1408433.JHXV01000001_gene946	3.2e-08	66.2	Cryomorphaceae				ko:K07126					ko00000				Bacteria	1I22V@117743,2PB39@246874,4NP2Z@976,COG2849@1,COG2849@2	NA|NA|NA	S	MORN repeat variant
MAG.T21.18_01047	1123234.AUKI01000011_gene1164	1.1e-128	466.8	Flavobacteriia	hutI		3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYME@117743,4NE6C@976,COG1228@1,COG1228@2	NA|NA|NA	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family
MAG.T21.18_01048	998674.ATTE01000001_gene1707	1.8e-14	86.7	Gammaproteobacteria				ko:K07052					ko00000				Bacteria	1QPQ0@1224,1S8GA@1236,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
MAG.T21.18_01049	1168034.FH5T_01095	2.1e-198	698.7	Bacteroidia	ftcD		2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100		R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147				Bacteria	2FMWT@200643,4NFE3@976,COG3404@1,COG3404@2,COG3643@1,COG3643@2	NA|NA|NA	E	Glutamate formimidoyltransferase
MAG.T21.18_01050	1279009.ADICEAN_00064	7.5e-141	508.1	Cytophagia				ko:K07001					ko00000				Bacteria	47KND@768503,4NF97@976,COG1752@1,COG1752@2	NA|NA|NA	S	Esterase of the alpha-beta hydrolase superfamily
MAG.T21.18_01051	1279009.ADICEAN_02376	8.8e-34	151.0	Cytophagia	gspK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931	2.7.1.8	ko:K18676	ko00520,ko01100,map00520,map01100		R01961	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	47MGQ@768503,4NEV4@976,COG2971@1,COG2971@2	NA|NA|NA	G	N-acetylglucosamine kinase
MAG.T21.18_01052	755732.Fluta_3942	3.4e-49	201.8	Cryomorphaceae	narL												Bacteria	1ICPE@117743,2PBHR@246874,4NNVV@976,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
MAG.T21.18_01053	525373.HMPREF0766_10327	1.8e-77	296.2	Sphingobacteriia	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013				ko00000,ko00001,ko01000,ko03016				Bacteria	1IPJ5@117747,4NE1K@976,COG1234@1,COG1234@2	NA|NA|NA	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MAG.T21.18_01054	926562.Oweho_0421	1.3e-12	80.5	Bacteroidetes													Bacteria	2DTID@1,33KGU@2,4NZE6@976	NA|NA|NA		
MAG.T21.18_01055	926549.KI421517_gene1342	8e-29	133.3	Cytophagia				ko:K04749					ko00000,ko03021				Bacteria	47R1F@768503,4NTPB@976,COG1366@1,COG1366@2	NA|NA|NA	T	Belongs to the anti-sigma-factor antagonist family
MAG.T21.18_01056	1124780.ANNU01000008_gene2623	6.3e-126	457.2	Cytophagia	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15490	Bacteria	47KS2@768503,4NFIU@976,COG0540@1,COG0540@2	NA|NA|NA	F	Belongs to the ATCase OTCase family
MAG.T21.18_01057	762903.Pedsa_1914	2.4e-51	208.8	Sphingobacteriia	pyrR	GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000,ko03000				Bacteria	1IQWE@117747,4NFI1@976,COG2065@1,COG2065@2	NA|NA|NA	F	uracil phosphoribosyltransferase
MAG.T21.18_01058	755732.Fluta_3334	2.8e-231	808.1	Cryomorphaceae	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011				Bacteria	1HXPG@117743,2PAMJ@246874,4NDW9@976,COG0539@1,COG0539@2	NA|NA|NA	J	Ribosomal protein S1-like RNA-binding domain
MAG.T21.18_01060	1122226.AUHX01000013_gene1311	8.9e-114	417.5	Flavobacteriia													Bacteria	1IJEU@117743,4PKTY@976,COG3291@1,COG3291@2	NA|NA|NA	O	ASPIC and UnbV
MAG.T21.18_01061	392500.Swoo_1180	1.3e-62	246.5	Shewanellaceae	ygdQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1MWC9@1224,1T1GE@1236,2QBAR@267890,COG0861@1,COG0861@2	NA|NA|NA	P	PFAM Integral membrane protein TerC
MAG.T21.18_01062	1408433.JHXV01000022_gene3146	9.6e-97	360.9	Cryomorphaceae													Bacteria	1IF0R@117743,2PBBM@246874,4NM44@976,COG1807@1,COG1807@2	NA|NA|NA	M	Alg9-like mannosyltransferase family
MAG.T21.18_01063	760192.Halhy_1966	6.1e-94	351.3	Sphingobacteriia													Bacteria	1ISNS@117747,4NFI8@976,COG1215@1,COG1215@2	NA|NA|NA	M	Pfam:DUF2029
MAG.T21.18_01064	1121898.Q766_10440	3.6e-221	774.6	Flavobacterium													Bacteria	1HY8A@117743,2NUMJ@237,4NFBK@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	BAAT / Acyl-CoA thioester hydrolase C terminal
MAG.T21.18_01065	1237149.C900_03556	3.1e-30	138.3	Cytophagia													Bacteria	2AN5I@1,31D3D@2,47QVV@768503,4NQTI@976	NA|NA|NA	S	Domain of unknown function (DUF4920)
MAG.T21.18_01067	1492738.FEM21_08620	4.1e-43	180.6	Flavobacterium													Bacteria	1I5HD@117743,2NXV5@237,4NUJU@976,COG0590@1,COG0590@2	NA|NA|NA	FJ	tRNA wobble adenosine to inosine editing
MAG.T21.18_01068	761193.Runsl_2680	4.5e-41	174.1	Cytophagia													Bacteria	47R22@768503,4PN8I@976,COG3153@1,COG3153@2	NA|NA|NA	S	Acetyltransferase (GNAT) domain
MAG.T21.18_01069	1034807.FBFL15_2636	2.1e-36	158.7	Flavobacteriia													Bacteria	1I984@117743,4NRI8@976,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
MAG.T21.18_01071	411154.GFO_2646	2.5e-112	412.5	Flavobacteriia				ko:K05820					ko00000,ko02000	2.A.1.27			Bacteria	1I107@117743,4NK2M@976,COG2271@1,COG2271@2	NA|NA|NA	G	Acetyl-coenzyme A transporter 1
MAG.T21.18_01072	1506583.JQJY01000005_gene2178	2.1e-273	948.3	Flavobacterium	copA2												Bacteria	1HWXY@117743,2NT1D@237,4NE3N@976,COG2132@1,COG2132@2	NA|NA|NA	Q	Multicopper oxidase
MAG.T21.18_01073	525373.HMPREF0766_12643	1.3e-46	193.7	Sphingobacteriia	mtrC			ko:K02005,ko:K13888		M00709			ko00000,ko00002,ko02000	8.A.1			Bacteria	1IP2I@117747,4PHXN@976,COG0845@1,COG0845@2,COG2608@1,COG2608@2	NA|NA|NA	MP	Protein of unknown function (DUF3347)
MAG.T21.18_01074	1122605.KB893638_gene3456	1.5e-272	945.7	Sphingobacteriia			3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1IQ0B@117747,4NERS@976,COG2217@1,COG2217@2	NA|NA|NA	P	Heavy metal translocating P-type atpase
MAG.T21.18_01075	1121899.Q764_13215	3.4e-15	88.2	Flavobacterium			3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1HWUI@117743,2NTDC@237,4NERS@976,COG2217@1,COG2217@2	NA|NA|NA	P	heavy metal translocating P-type ATPase
MAG.T21.18_01076	702438.HMPREF9431_01174	1e-43	183.3	Bacteroidia													Bacteria	2G35B@200643,4NNW7@976,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.18_01077	1121904.ARBP01000011_gene1483	3.1e-131	476.1	Cytophagia				ko:K07277					ko00000,ko02000,ko03029	1.B.33			Bacteria	47KRB@768503,4NE80@976,COG4775@1,COG4775@2	NA|NA|NA	M	Outer membrane protein protective antigen OMA87
MAG.T21.18_01078	1121904.ARBP01000011_gene1484	1.5e-154	554.7	Cytophagia													Bacteria	47JE0@768503,4NF7F@976,COG2911@1,COG2911@2	NA|NA|NA	M	PFAM Family of
MAG.T21.18_01079	1237149.C900_04091	2.8e-83	315.1	Cytophagia				ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	47KMI@768503,4NFDW@976,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter
MAG.T21.18_01080	1122176.KB903534_gene2220	7.1e-92	344.4	Sphingobacteriia				ko:K02005					ko00000				Bacteria	1IPZS@117747,4NDUH@976,COG0845@1,COG0845@2	NA|NA|NA	M	Efflux transporter, RND family, MFP subunit
MAG.T21.18_01081	1250278.JQNQ01000001_gene817	1.8e-40	172.9	Flavobacteriia	rebM												Bacteria	1HXEZ@117743,4NE6P@976,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase
MAG.T21.18_01082	755732.Fluta_2762	2.8e-121	442.2	Cryomorphaceae	pdhC		1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1HZ6M@117743,2PA4P@246874,4NFB9@976,COG0508@1,COG0508@2	NA|NA|NA	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MAG.T21.18_01083	755732.Fluta_2761	2.8e-124	451.8	Cryomorphaceae	pdhA		1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1HX15@117743,2PAKR@246874,4NF2J@976,COG1071@1,COG1071@2	NA|NA|NA	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MAG.T21.18_01084	1249997.JHZW01000003_gene3898	4.6e-29	134.4	Maribacter	cdd		2.4.2.2,3.5.4.5	ko:K00756,ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01570,R01876,R01878,R02296,R02484,R02485,R08221	RC00063,RC00074,RC00514	ko00000,ko00001,ko01000				Bacteria	1I1A3@117743,2PHG3@252356,4NQED@976,COG0295@1,COG0295@2	NA|NA|NA	F	Cytidine and deoxycytidylate deaminase zinc-binding region
MAG.T21.18_01085	1313421.JHBV01000020_gene5205	5e-45	188.0	Bacteroidetes	ygiF	GO:0003674,GO:0003824,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0046872,GO:0050355	3.6.1.25	ko:K18446					ko00000,ko01000				Bacteria	4NM6K@976,COG3025@1,COG3025@2	NA|NA|NA	S	VTC domain
MAG.T21.18_01086	313603.FB2170_11471	8.9e-44	183.7	Flavobacteriia													Bacteria	1IJ0R@117743,308PC@2,4NR4D@976,arCOG14808@1	NA|NA|NA	S	Domain of unknown function (DUF4956)
MAG.T21.18_01087	742725.HMPREF9450_02268	1.5e-51	209.1	Rikenellaceae	ispF	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.228,2.7.7.60,4.6.1.12	ko:K00554,ko:K00991,ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05633,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016			iPC815.YPO3360	Bacteria	22UEM@171550,2FNVA@200643,4NP0N@976,COG0245@1,COG0245@2	NA|NA|NA	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MAG.T21.18_01088	1408433.JHXV01000034_gene14	3.5e-100	372.1	Cryomorphaceae	porV												Bacteria	1HY15@117743,2PA6Z@246874,4NDZW@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.18_01089	755732.Fluta_2550	4.5e-231	808.5	Cryomorphaceae	porU												Bacteria	1HYJD@117743,2PAHV@246874,4NDY7@976,COG1572@1,COG1572@2	NA|NA|NA	S	Peptidase family C25
MAG.T21.18_01090	755732.Fluta_2549	1.7e-94	352.8	Cryomorphaceae													Bacteria	1HZRC@117743,2PANF@246874,4NG13@976,COG4772@1,COG4772@2	NA|NA|NA	P	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_01091	1408433.JHXV01000034_gene11	3.1e-171	608.6	Cryomorphaceae	pkn1												Bacteria	1HXGH@117743,2PA9N@246874,4NE51@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_01092	111105.HR09_08950	6.9e-104	384.4	Porphyromonadaceae	murF		6.3.2.10,6.3.2.13	ko:K01928,ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502		R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	22WG2@171551,2FN92@200643,4NDWD@976,COG0770@1,COG0770@2	NA|NA|NA	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAG.T21.18_01093	519989.ECTPHS_05395	5.8e-35	154.5	Chromatiales	erfK												Bacteria	1MYZT@1224,1S8PS@1236,1WY8E@135613,COG1376@1,COG1376@2	NA|NA|NA	S	ErfK YbiS YcfS YnhG family protein
MAG.T21.18_01094	1122176.KB903549_gene1251	5.4e-80	305.4	Sphingobacteriia				ko:K07278					ko00000,ko02000	1.B.33.2.4			Bacteria	1IS7K@117747,4PKYQ@976,COG0729@1,COG0729@2	NA|NA|NA	M	Surface antigen
MAG.T21.18_01095	926562.Oweho_1027	1.3e-80	306.2	Cryomorphaceae	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340				ko00000,ko00001,ko01000,ko03400				Bacteria	1HY4H@117743,2PARZ@246874,4NE2B@976,COG0692@1,COG0692@2	NA|NA|NA	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAG.T21.18_01096	313596.RB2501_12512	6.2e-27	127.1	Flavobacteriia	osmC			ko:K06889,ko:K07397					ko00000				Bacteria	1I2VB@117743,4NQ66@976,COG1765@1,COG1765@2	NA|NA|NA	O	redox protein regulator of disulfide bond formation
MAG.T21.18_01097	1408433.JHXV01000002_gene460	5.3e-32	144.8	Cryomorphaceae													Bacteria	1I9N3@117743,28MPU@1,2PC5G@246874,2ZAYW@2,4PJIE@976	NA|NA|NA		
MAG.T21.18_01098	755732.Fluta_2251	6.4e-122	443.7	Cryomorphaceae	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100		R07767,R07768	RC01978	ko00000,ko00001,ko01000				Bacteria	1HXXW@117743,2PADK@246874,4NEB5@976,COG0320@1,COG0320@2	NA|NA|NA	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MAG.T21.18_01099	1550091.JROE01000013_gene63	4.5e-119	434.5	Sphingobacteriia	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1IQAX@117747,4NEMF@976,COG0057@1,COG0057@2	NA|NA|NA	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAG.T21.18_01100	926562.Oweho_2422	1.7e-92	345.9	Cryomorphaceae	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005			iE2348C_1286.E2348C_0457	Bacteria	1HWZZ@117743,2PADT@246874,4NEF1@976,COG2908@1,COG2908@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
MAG.T21.18_01101	1408433.JHXV01000006_gene2788	3.5e-178	632.5	Cryomorphaceae													Bacteria	1HYBR@117743,2PAP0@246874,4NEXH@976,COG0308@1,COG0308@2	NA|NA|NA	E	peptidase M1
MAG.T21.18_01102	1121904.ARBP01000005_gene4844	7e-52	211.5	Cytophagia													Bacteria	47N2D@768503,4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	O	Domain of unknown function (DUF4369)
MAG.T21.18_01103	755732.Fluta_2846	1.7e-170	605.9	Cryomorphaceae	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1I8AX@117743,2PAB3@246874,4NF3B@976,COG0064@1,COG0064@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAG.T21.18_01104	755732.Fluta_2847	6e-98	364.0	Cryomorphaceae	punA		2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000				Bacteria	1HWSP@117743,2PA74@246874,4NE4J@976,COG0005@1,COG0005@2	NA|NA|NA	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MAG.T21.18_01105	1127692.HMPREF9075_01671	1.8e-57	229.9	Capnocytophaga	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005			iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	Bacteria	1ER3T@1016,1HWU8@117743,4NE2I@976,COG1663@1,COG1663@2	NA|NA|NA	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
MAG.T21.18_01106	700598.Niako_5484	1.7e-111	409.5	Sphingobacteriia	yqfO		3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP4G@117747,4NF51@976,COG0327@1,COG0327@2	NA|NA|NA	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAG.T21.18_01107	742817.HMPREF9449_02841	1.3e-31	143.7	Porphyromonadaceae	CP_0228		3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	22W5K@171551,2FPGP@200643,4NE36@976,COG1579@1,COG1579@2	NA|NA|NA	S	Zinc ribbon domain protein
MAG.T21.18_01108	1408473.JHXO01000013_gene534	1e-47	198.0	Bacteroidia													Bacteria	2FM7S@200643,4NFS7@976,COG2067@1,COG2067@2	NA|NA|NA	I	Outer membrane protein transport protein, Ompp1 FadL TodX
MAG.T21.18_01110	553175.POREN0001_0433	1.9e-219	768.5	Porphyromonadaceae	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	22X3K@171551,2FMZT@200643,4NEAF@976,COG0442@1,COG0442@2	NA|NA|NA	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
MAG.T21.18_01111	1433126.BN938_3047	5.1e-53	214.5	Rikenellaceae													Bacteria	22USQ@171550,2BB8B@1,2FXHA@200643,324R0@2,4NQG8@976	NA|NA|NA		
MAG.T21.18_01113	1121104.AQXH01000001_gene816	2.3e-90	340.5	Sphingobacteriia	rmuC			ko:K09760					ko00000				Bacteria	1INWB@117747,4NE04@976,COG1322@1,COG1322@2	NA|NA|NA	S	PFAM RmuC family
MAG.T21.18_01114	1356852.N008_12255	5.9e-60	237.7	Cytophagia	trmH		2.1.1.185	ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	47JZC@768503,4NF6H@976,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAG.T21.18_01116	1185876.BN8_00772	0.0	1278.8	Cytophagia				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	47MNQ@768503,4NDZC@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2	NA|NA|NA	O	SprB repeat
MAG.T21.18_01117	991.IW20_08645	9.8e-60	237.3	Flavobacterium													Bacteria	1HWKC@117743,2NT6M@237,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	membrane
MAG.T21.18_01118	1408813.AYMG01000039_gene2341	4.4e-99	369.0	Sphingobacteriia													Bacteria	1IPAI@117747,4NE6G@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_01119	1408433.JHXV01000038_gene2216	7.1e-156	557.4	Cryomorphaceae													Bacteria	1HYIP@117743,2PBI8@246874,4NEGK@976,COG0535@1,COG0535@2	NA|NA|NA	S	radical SAM domain protein
MAG.T21.18_01120	926562.Oweho_1031	3.1e-129	469.5	Flavobacteriia			3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1HY7M@117743,4NGTZ@976,COG0308@1,COG0308@2	NA|NA|NA	E	Aminopeptidase N
MAG.T21.18_01121	1341181.FLJC2902T_05060	2.3e-23	117.1	Flavobacterium													Bacteria	1IKDI@117743,2P0DY@237,4PKPT@976,COG3386@1,COG3386@2	NA|NA|NA	G	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_01122	1227739.Hsw_2384	3.1e-97	362.8	Cytophagia	ltaS2												Bacteria	47K4G@768503,4NFI9@976,COG1368@1,COG1368@2	NA|NA|NA	M	COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily
MAG.T21.18_01123	755732.Fluta_0750	5.7e-175	620.5	Cryomorphaceae	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147				Bacteria	1HWRR@117743,2PAAC@246874,4NF5M@976,COG0148@1,COG0148@2	NA|NA|NA	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAG.T21.18_01124	1408433.JHXV01000042_gene1443	3.4e-126	458.4	Cryomorphaceae	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1383	Bacteria	1HXZ3@117743,2PAK9@246874,4NEQI@976,COG0505@1,COG0505@2	NA|NA|NA	F	PFAM Carbamoyl-phosphate synthase small chain, CPSase domain
MAG.T21.18_01125	1461577.CCMH01000003_gene941	1.4e-44	186.0	Flavobacteriia	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904		ko:K02879	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I1B5@117743,4NNW0@976,COG0203@1,COG0203@2	NA|NA|NA	J	ribosomal protein l17
MAG.T21.18_01126	755732.Fluta_0753	7.5e-143	513.5	Cryomorphaceae	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1HX6J@117743,2PA8U@246874,4NE8W@976,COG0202@1,COG0202@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAG.T21.18_01127	929703.KE386491_gene2487	7.2e-56	223.4	Cytophagia	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112		ko:K02986	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	47K3X@768503,4NEMZ@976,COG0522@1,COG0522@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAG.T21.18_01128	1123400.KB904752_gene845	9.5e-27	128.6	Proteobacteria													Bacteria	1QWWH@1224,COG2834@1,COG2834@2,COG3420@1,COG3420@2	NA|NA|NA	P	Beta-L-arabinofuranosidase, GH127
MAG.T21.18_01129	1434325.AZQN01000001_gene207	1.7e-67	262.7	Cytophagia													Bacteria	47KWJ@768503,4NGF1@976,COG1432@1,COG1432@2	NA|NA|NA	S	OST-HTH/LOTUS domain
MAG.T21.18_01130	1122179.KB890425_gene3528	3.7e-18	97.1	Sphingobacteriia	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1ITX1@117747,4NUMZ@976,COG3237@1,COG3237@2	NA|NA|NA	S	Belongs to the UPF0337 (CsbD) family
MAG.T21.18_01131	1408433.JHXV01000015_gene1733	9.6e-88	332.0	Cryomorphaceae				ko:K06885					ko00000				Bacteria	1IKDF@117743,2PBK0@246874,4PP0F@976,COG1078@1,COG1078@2,COG2114@1,COG2114@2,COG3292@1,COG3292@2	NA|NA|NA	T	Adenylyl- / guanylyl cyclase, catalytic domain
MAG.T21.18_01132	742766.HMPREF9455_02236	1.3e-24	119.0	Porphyromonadaceae													Bacteria	22YDH@171551,2CZWI@1,2FTY4@200643,32T79@2,4NSNW@976	NA|NA|NA	S	DNA-binding protein
MAG.T21.18_01133	743722.Sph21_3878	1.2e-162	580.1	Sphingobacteriia	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1IQEP@117747,4NEJV@976,COG0513@1,COG0513@2	NA|NA|NA	L	Belongs to the DEAD box helicase family
MAG.T21.18_01135	1408473.JHXO01000010_gene3748	1.3e-142	514.2	Bacteroidia													Bacteria	2FMKE@200643,4NEE5@976,COG4485@1,COG4485@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score 10.00
MAG.T21.18_01136	1408473.JHXO01000010_gene3757	3.7e-110	405.2	Bacteroidia													Bacteria	2FS76@200643,4NE6S@976,COG0438@1,COG0438@2	NA|NA|NA	M	glycosyl transferase
MAG.T21.18_01137	1121104.AQXH01000005_gene187	1e-58	234.6	Sphingobacteriia													Bacteria	1IP8T@117747,4NEVQ@976,COG2244@1,COG2244@2	NA|NA|NA	S	Membrane protein involved in the export of O-antigen and teichoic acid
MAG.T21.18_01138	1288963.ADIS_0202	1.8e-55	222.6	Bacteria													Bacteria	COG1086@1,COG1086@2	NA|NA|NA	GM	Polysaccharide biosynthesis protein
MAG.T21.18_01139	1267534.KB906757_gene900	2.2e-30	139.4	Bacteria													Bacteria	COG4123@1,COG4123@2	NA|NA|NA	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MAG.T21.18_01140	1123057.P872_15810	1.3e-52	213.8	Cytophagia													Bacteria	47TYE@768503,4NNVW@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01141	643867.Ftrac_0772	3.7e-33	147.9	Cytophagia													Bacteria	47SAV@768503,4NQCK@976,COG4731@1,COG4731@2	NA|NA|NA	S	Uncharacterized protein conserved in bacteria (DUF2147)
MAG.T21.18_01142	1408433.JHXV01000005_gene2360	8.8e-08	65.1	Cryomorphaceae													Bacteria	1HY2Q@117743,2PBZ4@246874,4NG50@976,COG3055@1,COG3055@2	NA|NA|NA	S	PFAM Kelch motif
MAG.T21.18_01143	153721.MYP_2228	2.3e-241	842.4	Cytophagia			3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	47JGQ@768503,4NEXH@976,COG0308@1,COG0308@2	NA|NA|NA	E	PFAM Peptidase M1, membrane alanine aminopeptidase
MAG.T21.18_01144	1408473.JHXO01000010_gene3577	1.3e-46	193.7	Bacteroidetes	rbn			ko:K03466,ko:K07058					ko00000,ko03036	3.A.12			Bacteria	4NFY6@976,COG1295@1,COG1295@2	NA|NA|NA	S	ribonuclease BN
MAG.T21.18_01145	483216.BACEGG_02234	2.8e-90	338.6	Bacteroidaceae	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1988	Bacteria	2FMJM@200643,4AKC0@815,4NDXF@976,COG0157@1,COG0157@2	NA|NA|NA	H	Belongs to the NadC ModD family
MAG.T21.18_01146	391596.PBAL39_06081	5.3e-15	87.4	Sphingobacteriia													Bacteria	1IUPS@117747,2E4AG@1,32Z66@2,4NUXA@976	NA|NA|NA	S	Domain of unknown function (DUF4783)
MAG.T21.18_01147	886379.AEWI01000144_gene3271	1.4e-27	129.4	Marinilabiliaceae	rlmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.177	ko:K00783					ko00000,ko01000,ko03009				Bacteria	2FN6G@200643,3XK6H@558415,4NMFP@976,COG1576@1,COG1576@2	NA|NA|NA	J	Predicted SPOUT methyltransferase
MAG.T21.18_01148	1385935.N836_33000	4.8e-24	118.6	Oscillatoriales	crtF												Bacteria	1GQNU@1117,1HHXR@1150,COG0500@1,COG2226@2	NA|NA|NA	Q	Methionine biosynthesis protein MetW
MAG.T21.18_01149	1279009.ADICEAN_00545	4e-55	222.6	Cytophagia													Bacteria	28ICP@1,2Z8EZ@2,47N2N@768503,4NKKI@976	NA|NA|NA		
MAG.T21.18_01150	1209072.ALBT01000007_gene2745	1.8e-19	103.6	Cellvibrio													Bacteria	1FGU0@10,1NTXD@1224,1SMSD@1236,COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.18_01151	1313421.JHBV01000016_gene5472	1.8e-45	190.3	Bacteroidetes													Bacteria	4NG0D@976,COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.18_01152	74547.PMT_0086	2.7e-36	159.5	Cyanobacteria	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1G6HK@1117,COG0451@1,COG0451@2	NA|NA|NA	GM	PFAM NAD dependent epimerase dehydratase family
MAG.T21.18_01153	643867.Ftrac_2226	1.5e-53	216.5	Cytophagia													Bacteria	47YDM@768503,4P0WQ@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_01154	984262.SGRA_4063	9.8e-35	154.5	Bacteroidetes													Bacteria	4P3DN@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01155	643867.Ftrac_2222	9.4e-57	227.6	Bacteria			2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100		R00292	RC00005	ko00000,ko00001,ko01000,ko01003		GT4		Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.18_01156	1121957.ATVL01000008_gene4273	1.1e-51	211.1	Cytophagia	wzxA												Bacteria	47VIS@768503,4NR8U@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
MAG.T21.18_01157	1501391.LG35_01060	1.2e-50	206.5	Rikenellaceae	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100		R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	22UFR@171550,2FP46@200643,4NM42@976,COG0127@1,COG0127@2	NA|NA|NA	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAG.T21.18_01158	1121129.KB903367_gene2675	1.9e-58	233.0	Porphyromonadaceae	ddl		6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	22WV1@171551,2FNMC@200643,4NE9P@976,COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
MAG.T21.18_01159	886379.AEWI01000030_gene298	2.9e-36	159.1	Marinilabiliaceae	spk1		2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	2FPS4@200643,3XJ68@558415,4NSUI@976,COG2815@1,COG2815@2	NA|NA|NA	S	PASTA
MAG.T21.18_01160	755732.Fluta_2097	1.5e-74	287.7	Cryomorphaceae													Bacteria	1I8D6@117743,28M1N@1,2PARN@246874,2ZAGE@2,4NIDD@976	NA|NA|NA		
MAG.T21.18_01161	927658.AJUM01000034_gene137	5e-121	441.0	Marinilabiliaceae	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180					ko00000,ko01000,ko03009,ko03016			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	2FMD1@200643,3XJJR@558415,4NEV3@976,COG0564@1,COG0564@2	NA|NA|NA	J	S4 RNA-binding domain
MAG.T21.18_01162	1121129.KB903360_gene3347	2.4e-57	229.6	Porphyromonadaceae	menE		6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000				Bacteria	22X5D@171551,2FM16@200643,4NEXK@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	O-succinylbenzoic acid--CoA ligase
MAG.T21.18_01163	1168289.AJKI01000025_gene1462	1.1e-88	333.6	Marinilabiliaceae	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0553	Bacteria	2FMXR@200643,3XJP1@558415,4NEBX@976,COG4948@1,COG4948@2	NA|NA|NA	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
MAG.T21.18_01164	1356852.N008_14295	2.2e-72	279.3	Cytophagia	menA	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006			iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737	Bacteria	47JDA@768503,4NGCJ@976,COG1575@1,COG1575@2	NA|NA|NA	H	Belongs to the MenA family. Type 1 subfamily
MAG.T21.18_01165	1349822.NSB1T_13055	4.2e-116	425.2	Porphyromonadaceae	menD		2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000				Bacteria	22W02@171551,2FMSK@200643,4NETZ@976,COG1165@1,COG1165@2	NA|NA|NA	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MAG.T21.18_01166	313596.RB2501_15744	1.6e-42	180.3	Flavobacteriia	menF	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008909,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009233,GO:0009234,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042180,GO:0042181,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046872,GO:0050486,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901661,GO:1901663,GO:1902494	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000			iECABU_c1320.ECABU_c26010,iECIAI39_1322.ECIAI39_2413,iSF_1195.SF2344,iS_1188.S2478,ic_1306.c2809	Bacteria	1HX5V@117743,4NF6U@976,COG1169@1,COG1169@2	NA|NA|NA	HQ	Isochorismate synthase
MAG.T21.18_01167	1408433.JHXV01000001_gene939	6.8e-29	133.7	Cryomorphaceae	menI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0034641,GO:0042180,GO:0042181,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000				Bacteria	1I2BT@117743,2PB6T@246874,4NNYG@976,COG2050@1,COG2050@2	NA|NA|NA	Q	Thioesterase superfamily
MAG.T21.18_01168	925409.KI911562_gene1090	2e-65	255.8	Sphingobacteriia													Bacteria	1INQ4@117747,4NGXP@976,COG0745@1,COG0745@2	NA|NA|NA	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.18_01169	926562.Oweho_3488	1.4e-06	60.5	Bacteria													Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_01170	313596.RB2501_07485	1.6e-81	311.2	Flavobacteriia	addB		3.1.11.5,3.6.4.12	ko:K01144,ko:K02259,ko:K16899	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko01000,ko03029,ko03400	3.D.4.4			Bacteria	1HWXQ@117743,4NFZQ@976,COG2887@1,COG2887@2,COG3893@1,COG3893@2	NA|NA|NA	L	COG3893 Inactivated superfamily I helicase
MAG.T21.18_01172	755732.Fluta_0072	6e-131	475.3	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1IKD0@117743,2PAFR@246874,4NJYT@976,COG3291@1,COG3291@2	NA|NA|NA	S	C-terminal domain of CHU protein family
MAG.T21.18_01173	487796.Flav2ADRAFT_0799	3e-27	128.3	Flavobacteriia	elaA	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564		ko:K02348					ko00000				Bacteria	1I23R@117743,4NQPR@976,COG2153@1,COG2153@2	NA|NA|NA	S	(GNAT) family
MAG.T21.18_01174	313596.RB2501_07500	2e-112	414.1	Flavobacteriia	addA		3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1HWZS@117743,4NEX4@976,COG1074@1,COG1074@2	NA|NA|NA	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
MAG.T21.18_01175	468059.AUHA01000008_gene2792	1.4e-170	605.9	Sphingobacteriia	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS10830,iSB619.SA_RS08945	Bacteria	1INQM@117747,4NF6I@976,COG0108@1,COG0108@2,COG0807@1,COG0807@2	NA|NA|NA	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MAG.T21.18_01176	1121957.ATVL01000007_gene1748	2.3e-98	365.9	Cytophagia				ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	47KVT@768503,4NFD3@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01177	1408433.JHXV01000038_gene2219	5.5e-95	354.8	Cryomorphaceae													Bacteria	1IEBF@117743,2PB0Z@246874,4NFD3@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01178	929556.Solca_0221	1.8e-97	363.2	Sphingobacteriia				ko:K07091,ko:K11720	ko02010,map02010	M00320			ko00000,ko00001,ko00002,ko02000	1.B.42.1			Bacteria	1INY8@117747,4NE8B@976,COG0795@1,COG0795@2	NA|NA|NA	S	Permease, YjgP YjgQ family
MAG.T21.18_01179	867900.Celly_3183	2.9e-26	125.9	Cellulophaga													Bacteria	1F9BS@104264,1I21X@117743,4NNY1@976,COG3832@1,COG3832@2	NA|NA|NA	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_01181	1267211.KI669560_gene30	2e-20	105.5	Sphingobacteriia			3.4.19.5	ko:K03088,ko:K13051					ko00000,ko01000,ko01002,ko03021				Bacteria	1ITI3@117747,4NS9D@976,COG4319@1,COG4319@2	NA|NA|NA	S	Domain of unknown function (DUF4440)
MAG.T21.18_01182	1123276.KB893245_gene953	7.5e-43	180.6	Cytophagia													Bacteria	47N8U@768503,4NECA@976,COG0705@1,COG0705@2	NA|NA|NA	S	PFAM Rhomboid family
MAG.T21.18_01183	468059.AUHA01000003_gene1525	2.4e-33	148.7	Sphingobacteriia	gmhB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033692,GO:0034200,GO:0034637,GO:0034645,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046872,GO:0046914,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.82,3.1.3.83,6.3.2.10	ko:K01929,ko:K03273	ko00300,ko00540,ko00550,ko01100,ko01502,map00300,map00540,map00550,map01100,map01502	M00064	R04573,R04617,R05647,R09771	RC00017,RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01005,ko01011			iB21_1397.B21_00198,iEC55989_1330.EC55989_0198,iECBD_1354.ECBD_3418,iECB_1328.ECB_00199,iECD_1391.ECD_00199,iECIAI1_1343.ECIAI1_0202,iECO103_1326.ECO103_0200,iECSE_1348.ECSE_0202,iETEC_1333.ETEC_0196,iEcHS_1320.EcHS_A0204,iEcolC_1368.EcolC_3459	Bacteria	1IS1F@117747,4NNDD@976,COG0241@1,COG0241@2	NA|NA|NA	E	D,D-heptose 1,7-bisphosphate phosphatase
MAG.T21.18_01184	755732.Fluta_3488	2e-67	262.7	Cryomorphaceae	pabC		2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1HYPS@117743,2PAUN@246874,4NG0G@976,COG0115@1,COG0115@2	NA|NA|NA	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
MAG.T21.18_01185	700598.Niako_7310	4.7e-44	184.5	Sphingobacteriia	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K07735					ko00000,ko03000				Bacteria	1ISYC@117747,4NFQA@976,COG1678@1,COG1678@2	NA|NA|NA	K	acr, cog1678
MAG.T21.18_01186	118163.Ple7327_3212	2.4e-57	228.8	Pleurocapsales	pdxH		1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000			iJN678.pdxH	Bacteria	1G0HC@1117,3VJ47@52604,COG0259@1,COG0259@2	NA|NA|NA	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
MAG.T21.18_01188	1408473.JHXO01000011_gene3075	1.8e-55	222.6	Bacteroidia	trmH		2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	2FSSX@200643,4NFH3@976,COG0566@1,COG0566@2	NA|NA|NA	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA
MAG.T21.18_01189	153721.MYP_4845	1.2e-26	125.6	Cytophagia	hupB			ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	47V8W@768503,4NSK6@976,COG0776@1,COG0776@2	NA|NA|NA	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAG.T21.18_01190	1317122.ATO12_01935	9.6e-17	93.2	Aquimarina													Bacteria	1IHUF@117743,2YJQ6@290174,4NVCS@976,COG0662@1,COG0662@2	NA|NA|NA	G	Mannose-6-phosphate isomerase
MAG.T21.18_01191	313596.RB2501_13649	2e-84	319.3	Flavobacteriia	fmt		2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000				Bacteria	1HX64@117743,4NE8U@976,COG0223@1,COG0223@2	NA|NA|NA	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAG.T21.18_01192	700598.Niako_7006	2.9e-49	201.8	Sphingobacteriia	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1IS50@117747,4NP22@976,COG2094@1,COG2094@2	NA|NA|NA	L	Belongs to the DNA glycosylase MPG family
MAG.T21.18_01193	1089547.KB913013_gene2528	3.4e-141	508.8	Cytophagia	recQ2		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	47M73@768503,4NEFD@976,COG0514@1,COG0514@2	NA|NA|NA	L	ATP-dependent DNA helicase RecQ
MAG.T21.18_01194	1313301.AUGC01000006_gene166	2.2e-116	425.6	Bacteroidetes	ilvE		2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007			iAF987.Gmet_2853,iYO844.BSU38550	Bacteria	4NEJY@976,COG0115@1,COG0115@2	NA|NA|NA	E	branched-chain amino acid aminotransferase
MAG.T21.18_01195	1313265.JNIE01000001_gene240	8.9e-12	77.0	Bacteria	dnaJ			ko:K03686					ko00000,ko03029,ko03110				Bacteria	COG0484@1,COG0484@2	NA|NA|NA	O	heat shock protein binding
MAG.T21.18_01196	755732.Fluta_3578	4.4e-37	162.5	Cryomorphaceae													Bacteria	1IMR3@117743,2PBJ5@246874,4PBC0@976,COG3391@1,COG3391@2	NA|NA|NA	S	amine dehydrogenase activity
MAG.T21.18_01199	1137281.D778_00550	4.6e-27	127.5	Flavobacteriia													Bacteria	1I2Y5@117743,2DM8U@1,3273Z@2,4NQC2@976	NA|NA|NA		
MAG.T21.18_01200	1123240.ATVO01000004_gene1129	1.7e-10	72.8	Alphaproteobacteria													Bacteria	1NCVN@1224,2UGB2@28211,COG2041@1,COG2041@2	NA|NA|NA	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MAG.T21.18_01201	379066.GAU_3517	8.2e-51	206.8	Bacteria	dps			ko:K04047					ko00000,ko03036				Bacteria	COG0783@1,COG0783@2	NA|NA|NA	P	Belongs to the Dps family
MAG.T21.18_01202	926562.Oweho_0359	3.4e-34	151.8	Flavobacteriia													Bacteria	1I1SI@117743,4NUTN@976,COG2318@1,COG2318@2	NA|NA|NA	S	DinB superfamily
MAG.T21.18_01203	1237149.C900_01948	3.4e-161	575.1	Cytophagia	sulP	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039		ko:K03321					ko00000,ko02000	2.A.53.3		iSbBS512_1146.SbBS512_E1370	Bacteria	47P6B@768503,4NF1C@976,COG0659@1,COG0659@2	NA|NA|NA	P	Sulfate permease family
MAG.T21.18_01204	1492738.FEM21_12140	4.6e-75	287.7	Flavobacterium													Bacteria	1HXES@117743,2NTFP@237,4NGVV@976,COG0745@1,COG0745@2	NA|NA|NA	T	Transcriptional regulator
MAG.T21.18_01205	743722.Sph21_2559	1.5e-87	330.1	Sphingobacteriia													Bacteria	1IR05@117747,4PKDW@976,COG0642@1,COG2205@2	NA|NA|NA	T	signal transduction histidine kinase
MAG.T21.18_01206	1121899.Q764_13080	5.7e-32	144.1	Flavobacterium	ykoJ												Bacteria	1IEN1@117743,2NY22@237,4P9DA@976,COG3212@1,COG3212@2	NA|NA|NA	S	Putative beta-lactamase-inhibitor-like, PepSY-like
MAG.T21.18_01207	1408433.JHXV01000008_gene121	4.2e-69	268.9	Bacteroidetes													Bacteria	4NNIP@976,COG3204@1,COG3204@2	NA|NA|NA	S	SdiA-regulated
MAG.T21.18_01209	929556.Solca_3835	4.2e-22	110.9	Bacteroidetes													Bacteria	4NZS3@976,COG0346@1,COG0346@2	NA|NA|NA	E	lactoylglutathione lyase activity
MAG.T21.18_01210	748247.AZKH_3845	6.1e-21	106.7	Rhodocyclales	yggU			ko:K09131					ko00000				Bacteria	1MZ4E@1224,2KX5K@206389,2VWDY@28216,COG1872@1,COG1872@2	NA|NA|NA	S	DUF167
MAG.T21.18_01211	1173024.KI912151_gene2226	1.5e-54	221.1	Bacteria	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
MAG.T21.18_01212	395964.KE386496_gene636	9.7e-214	749.6	Beijerinckiaceae			2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1MW3A@1224,2TQQA@28211,3NBTH@45404,COG0286@1,COG0286@2	NA|NA|NA	L	PFAM N-6 DNA methylase
MAG.T21.18_01213	592029.DDD_0098	3.1e-43	182.2	Flavobacteriia			2.1.1.72	ko:K03556,ko:K06223	ko03430,map03430				ko00000,ko00001,ko01000,ko02048,ko03000,ko03032,ko03400				Bacteria	1I3W0@117743,4NPSQ@976,COG3177@1,COG3177@2	NA|NA|NA	S	Fic/DOC family
MAG.T21.18_01214	323098.Nwi_0270	0.0	1199.1	Bradyrhizobiaceae			3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1QTS7@1224,2TUKC@28211,3JXID@41294,COG4096@1,COG4096@2	NA|NA|NA	L	EcoEI R protein C-terminal
MAG.T21.18_01215	926556.Echvi_3330	8.8e-38	162.9	Cytophagia	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06193	ko01120,map01120				ko00000				Bacteria	47QCE@768503,4NEFZ@976,COG2824@1,COG2824@2	NA|NA|NA	P	TIGRFAM alkylphosphonate utilization operon protein PhnA
MAG.T21.18_01219	153721.MYP_3858	1.5e-16	93.2	Bacteroidetes	amyB3												Bacteria	4NY26@976,COG4733@1,COG4733@2	NA|NA|NA	S	SPTR Putative
MAG.T21.18_01220	1183438.GKIL_3088	3.2e-78	299.3	Cyanobacteria			3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	1GQFF@1117,COG4529@1,COG4529@2	NA|NA|NA	S	FAD-NAD(P)-binding
MAG.T21.18_01221	153721.MYP_1956	8.2e-74	283.5	Cytophagia	lsfA		1.11.1.15	ko:K03386,ko:K03665	ko04214,map04214				ko00000,ko00001,ko01000,ko03009,ko04147				Bacteria	47KEE@768503,4NEZZ@976,COG0450@1,COG0450@2	NA|NA|NA	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.18_01222	1124780.ANNU01000042_gene626	1.4e-38	166.0	Cytophagia				ko:K13643					ko00000,ko03000				Bacteria	47P88@768503,4NNN2@976,COG1959@1,COG1959@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.18_01223	385682.AFSL01000015_gene2659	1.1e-137	496.9	Marinilabiliaceae	cvrA			ko:K03316,ko:K11105					ko00000,ko02000	2.A.36,2.A.36.6			Bacteria	2FMZZ@200643,3XISY@558415,4NFNS@976,COG3263@1,COG3263@2	NA|NA|NA	P	Sodium/hydrogen exchanger family
MAG.T21.18_01225	985255.APHJ01000035_gene18	4.8e-107	394.8	Gillisia													Bacteria	1HX12@117743,2P7B6@244698,4NEUU@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major Facilitator Superfamily
MAG.T21.18_01226	1122604.JONR01000004_gene851	2.7e-78	300.1	Xanthomonadales													Bacteria	1MUMZ@1224,1T234@1236,1X903@135614,COG0457@1,COG0457@2,COG5616@1,COG5616@2	NA|NA|NA	S	Adenylate cyclase
MAG.T21.18_01227	1353276.JADR01000014_gene2989	4.7e-15	88.6	Flavobacteriia													Bacteria	1I52E@117743,2E3AK@1,32YA3@2,4NUYM@976	NA|NA|NA		
MAG.T21.18_01228	1121104.AQXH01000001_gene1547	1.9e-50	206.1	Sphingobacteriia													Bacteria	1IZWF@117747,2E3AK@1,32YA3@2,4PAQ0@976	NA|NA|NA		
MAG.T21.18_01229	643867.Ftrac_2459	5.2e-51	208.0	Cytophagia													Bacteria	2E3AK@1,32YA3@2,47V7P@768503,4NT88@976	NA|NA|NA		
MAG.T21.18_01230	1120965.AUBV01000014_gene1145	6.2e-17	94.7	Bacteroidetes													Bacteria	2E3AK@1,2ZC5I@2,4NMX3@976	NA|NA|NA		
MAG.T21.18_01232	543728.Vapar_1442	2e-18	98.2	Comamonadaceae	feoA			ko:K04758					ko00000,ko02000				Bacteria	1NASN@1224,2VVSY@28216,4AFGG@80864,COG1918@1,COG1918@2	NA|NA|NA	P	PFAM FeoA family protein
MAG.T21.18_01233	1123504.JQKD01000046_gene1177	3.7e-204	718.0	Comamonadaceae	feoB			ko:K04759					ko00000,ko02000	9.A.8.1			Bacteria	1MUZC@1224,2VIRG@28216,4A9RM@80864,COG0370@1,COG0370@2	NA|NA|NA	P	Ferrous iron transport protein B
MAG.T21.18_01234	1492737.FEM08_29150	8.5e-30	136.7	Flavobacterium				ko:K07107					ko00000,ko01000				Bacteria	1I43T@117743,2NUI9@237,4NR2W@976,COG0824@1,COG0824@2	NA|NA|NA	S	Thioesterase-like superfamily
MAG.T21.18_01236	504472.Slin_0182	2e-31	143.3	Bacteria													Bacteria	2DN5F@1,32VNB@2	NA|NA|NA		
MAG.T21.18_01237	483219.LILAB_10430	1.4e-106	394.8	Myxococcales				ko:K17713					ko00000,ko02000	1.B.33.1			Bacteria	1R504@1224,2WKUI@28221,2YY0K@29,42QHC@68525,COG1520@1,COG1520@2,COG5184@1,COG5184@2	NA|NA|NA	DZ	Putative metal-binding motif
MAG.T21.18_01238	1123008.KB905704_gene478	9e-152	543.9	Bacteroidetes													Bacteria	4NH87@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01240	1121904.ARBP01000001_gene5713	4.6e-32	144.4	Bacteria													Bacteria	2E1HF@1,32WVJ@2	NA|NA|NA		
MAG.T21.18_01241	742817.HMPREF9449_00893	5.3e-15	87.4	Porphyromonadaceae	rbpA												Bacteria	22YT2@171551,2G2C1@200643,4NV5J@976,COG0724@1,COG0724@2	NA|NA|NA	S	Pfam:RRM_6
MAG.T21.18_01242	547559.Nmag_3075	6e-14	84.0	Halobacteria													Archaea	23W6P@183963,2XXZ5@28890,arCOG10953@1,arCOG10953@2157	NA|NA|NA		
MAG.T21.18_01243	760192.Halhy_4775	3.5e-12	79.7	Bacteria													Bacteria	COG4447@1,COG4447@2	NA|NA|NA	S	cellulose binding
MAG.T21.18_01244	468059.AUHA01000004_gene2392	1.4e-34	152.1	Bacteroidetes													Bacteria	4NSJX@976,COG4323@1,COG4323@2	NA|NA|NA	S	membrane
MAG.T21.18_01245	1122179.KB890413_gene4717	5.5e-30	138.7	Bacteroidetes													Bacteria	4NIC1@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller
MAG.T21.18_01246	864069.MicloDRAFT_00051220	1.9e-57	229.6	Methylobacteriaceae													Bacteria	1JX36@119045,1NWX3@1224,2TURQ@28211,COG0500@1,COG2226@2	NA|NA|NA	Q	ubiE/COQ5 methyltransferase family
MAG.T21.18_01247	714943.Mucpa_1801	5.8e-53	214.5	Sphingobacteriia	exsA	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141		ko:K20968	ko02025,map02025				ko00000,ko00001,ko03000				Bacteria	1ITYF@117747,4NGWC@976,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.18_01248	1492737.FEM08_18420	7.2e-13	80.5	Flavobacterium													Bacteria	1HYNI@117743,28HRC@1,2NUNX@237,2Z7YT@2,4NKDD@976	NA|NA|NA		
MAG.T21.18_01249	28229.ND2E_3536	1.6e-10	72.8	Gammaproteobacteria													Bacteria	1NKP8@1224,1SISV@1236,2DSYW@1,33HZI@2	NA|NA|NA		
MAG.T21.18_01250	1185876.BN8_04103	3e-97	363.6	Cytophagia													Bacteria	47N0D@768503,4NJ2Y@976,COG0745@1,COG0745@2,COG3292@1,COG3292@2,COG5002@1,COG5002@2	NA|NA|NA	T	Y_Y_Y domain
MAG.T21.18_01251	1356852.N008_05320	2.5e-43	182.2	Cytophagia													Bacteria	47PWE@768503,4NHTM@976,COG2197@1,COG2197@2	NA|NA|NA	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.18_01252	1408433.JHXV01000008_gene120	7.5e-38	164.5	Cryomorphaceae													Bacteria	1I2A1@117743,2PBKP@246874,4NNIP@976,COG3204@1,COG3204@2	NA|NA|NA	S	SdiA-regulated
MAG.T21.18_01254	1121904.ARBP01000017_gene5123	2.3e-55	223.0	Bacteria				ko:K06889					ko00000				Bacteria	COG1073@1,COG1073@2	NA|NA|NA	S	thiolester hydrolase activity
MAG.T21.18_01255	448385.sce6223	3.9e-81	308.5	Myxococcales			1.6.5.5	ko:K00344					ko00000,ko01000				Bacteria	1MX8A@1224,2WM4P@28221,2Z037@29,42QBD@68525,COG0604@1,COG0604@2	NA|NA|NA	C	Zinc-binding dehydrogenase
MAG.T21.18_01256	1121930.AQXG01000002_gene1974	1.4e-56	226.1	Sphingobacteriia													Bacteria	1IXRH@117747,4NQWV@976,COG0664@1,COG0664@2	NA|NA|NA	T	Cyclic nucleotide-monophosphate binding domain
MAG.T21.18_01257	1122179.KB890433_gene4058	9.6e-31	141.0	Sphingobacteriia	nsr		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	1IXGI@117747,4NIQJ@976,COG0793@1,COG0793@2	NA|NA|NA	M	Peptidase family S41
MAG.T21.18_01260	153721.MYP_3858	8.1e-10	70.9	Bacteroidetes	amyB3												Bacteria	4NY26@976,COG4733@1,COG4733@2	NA|NA|NA	S	SPTR Putative
MAG.T21.18_01265	414684.RC1_0095	7.6e-307	1059.7	Alphaproteobacteria	resA		3.1.21.5	ko:K01156					ko00000,ko01000,ko02048				Bacteria	1MX92@1224,2U18S@28211,COG1061@1,COG1061@2	NA|NA|NA	KL	Type III restriction enzyme, res subunit
MAG.T21.18_01266	1328313.DS2_14734	1.8e-224	785.4	Alteromonadaceae			2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	1MX9M@1224,1RNHM@1236,468AR@72275,COG2189@1,COG2189@2	NA|NA|NA	L	COG2189 Adenine specific DNA methylase Mod
MAG.T21.18_01267	292415.Tbd_0934	3.5e-71	276.2	Betaproteobacteria													Bacteria	1MVIU@1224,2VM71@28216,2Z7VT@2,arCOG06613@1	NA|NA|NA	S	AIPR protein
MAG.T21.18_01268	414684.RC1_0099	8.7e-301	1039.6	Rhodospirillales			2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	1MX6H@1224,2JR41@204441,2TUMR@28211,COG0553@1,COG0553@2	NA|NA|NA	L	SNF2 family N-terminal domain
MAG.T21.18_01269	1121481.AUAS01000007_gene1025	4.8e-34	151.8	Cytophagia	pssA		2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000				Bacteria	47PCF@768503,4NNUZ@976,COG1183@1,COG1183@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAG.T21.18_01270	1408433.JHXV01000029_gene3072	4.5e-112	411.4	Cryomorphaceae													Bacteria	1HZ3R@117743,2PA70@246874,4NE43@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.18_01271	1408433.JHXV01000029_gene3073	2.8e-281	975.7	Cryomorphaceae													Bacteria	1IMQK@117743,2PBES@246874,4NFAX@976,COG1572@1,COG1572@2	NA|NA|NA	S	Peptidase family C25
MAG.T21.18_01272	1124780.ANNU01000005_gene2363	6.6e-107	394.8	Cytophagia	lnt			ko:K03820					ko00000,ko01000		GT2		Bacteria	47JV8@768503,4NG4X@976,COG0815@1,COG0815@2	NA|NA|NA	M	Carbon-nitrogen hydrolase
MAG.T21.18_01273	1356852.N008_09270	5.4e-19	102.4	Cytophagia													Bacteria	47V9V@768503,4NSPG@976,COG2911@1,COG2911@2,COG3391@1,COG3391@2	NA|NA|NA	O	Protein conserved in bacteria
MAG.T21.18_01274	1123035.ARLA01000021_gene804	5.6e-71	275.0	Psychroflexus	pabB		2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1HY8U@117743,4C35S@83612,4NECR@976,COG0147@1,COG0147@2	NA|NA|NA	EH	Anthranilate synthase component I, N terminal region
MAG.T21.18_01275	1123276.KB893313_gene3843	6e-71	275.0	Cytophagia	tilS		6.3.4.19	ko:K04075			R09597	RC02633,RC02634	ko00000,ko01000,ko03016				Bacteria	47M2U@768503,4NEJS@976,COG0037@1,COG0037@2	NA|NA|NA	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAG.T21.18_01276	755732.Fluta_0406	1.5e-11	75.5	Cryomorphaceae													Bacteria	1IIF3@117743,2ENZ2@1,2PC5A@246874,33GJY@2,4NZ6P@976	NA|NA|NA		
MAG.T21.18_01277	762903.Pedsa_3600	9.5e-21	106.7	Sphingobacteriia			1.8.1.8	ko:K04084					ko00000,ko01000,ko03110	5.A.1.1			Bacteria	1ISZ1@117747,4NQID@976,COG4232@1,COG4232@2	NA|NA|NA	CO	Disulphide bond corrector protein DsbC
MAG.T21.18_01278	216432.CA2559_09878	4.1e-191	674.9	Flavobacteriia	dsbD		1.8.1.8	ko:K04084					ko00000,ko01000,ko03110	5.A.1.1			Bacteria	1HX34@117743,4NEW6@976,COG4232@1,COG4232@2	NA|NA|NA	CO	Thiol disulfide interchange protein
MAG.T21.18_01279	1121957.ATVL01000010_gene576	1.5e-66	259.2	Cytophagia	gmhA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	47KZ6@768503,4NJX7@976,COG0279@1,COG0279@2	NA|NA|NA	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
MAG.T21.18_01280	929556.Solca_3990	4.1e-204	717.6	Sphingobacteriia	comM			ko:K07391					ko00000				Bacteria	1INNX@117747,4NE0G@976,COG0606@1,COG0606@2	NA|NA|NA	O	chelatase, subunit chli
MAG.T21.18_01281	679189.HMPREF9019_1979	1.4e-13	83.6	Bacteroidia	tonB			ko:K03832					ko00000,ko02000	2.C.1.1			Bacteria	2FM72@200643,4NFH6@976,COG0810@1,COG0810@2	NA|NA|NA	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.18_01282	1168034.FH5T_18730	0.0	1340.5	Bacteroidia	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680		ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	2FMVF@200643,4NF7C@976,COG0653@1,COG0653@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAG.T21.18_01283	1517682.HW49_09525	4.2e-30	136.7	Porphyromonadaceae													Bacteria	22YD9@171551,2C8VT@1,2FTSK@200643,32RN1@2,4NS78@976	NA|NA|NA	S	Protein of unknown function (DUF2795)
MAG.T21.18_01284	927658.AJUM01000022_gene995	2.3e-48	198.7	Marinilabiliaceae	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.2.1.88,1.5.5.2,2.5.1.17	ko:K00798,ko:K13821	ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130	M00122	R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268	RC00080,RC00083,RC00216,RC00242,RC00255,RC00533	ko00000,ko00001,ko00002,ko01000,ko03000				Bacteria	2FQJ0@200643,3XK0P@558415,4NFHQ@976,COG2096@1,COG2096@2	NA|NA|NA	S	Cobalamin adenosyltransferase
MAG.T21.18_01285	1123248.KB893385_gene4872	2.6e-31	144.1	Bacteroidetes													Bacteria	4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	U	PFAM PKD domain
MAG.T21.18_01286	468059.AUHA01000002_gene443	9.5e-64	250.4	Sphingobacteriia													Bacteria	1IRXU@117747,4NG1S@976,COG4122@1,COG4122@2	NA|NA|NA	S	Methyltransferase domain
MAG.T21.18_01287	1434325.AZQN01000001_gene284	4.9e-47	194.1	Cytophagia	crtZ		1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000				Bacteria	47PV8@768503,4NMA9@976,COG3000@1,COG3000@2	NA|NA|NA	I	PFAM Fatty acid hydroxylase
MAG.T21.18_01290	761193.Runsl_1396	2.5e-146	525.4	Cytophagia	phr		4.1.99.3	ko:K01669					ko00000,ko01000,ko03400				Bacteria	47MVE@768503,4NEDW@976,COG0415@1,COG0415@2	NA|NA|NA	L	DNA photolyase
MAG.T21.18_01291	118173.KB235914_gene2162	2.3e-45	188.7	Cyanobacteria	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576	4.1.1.33,5.3.3.2	ko:K01597,ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01121,R01123	RC00453,RC00455	ko00000,ko00001,ko00002,ko01000				Bacteria	1GDFS@1117,COG1443@1,COG1443@2	NA|NA|NA	I	NUDIX domain
MAG.T21.18_01292	313606.M23134_07222	2e-91	342.4	Cytophagia	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99	ko:K00801,ko:K02291,ko:K10208	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	47J9F@768503,4NEIK@976,COG1562@1,COG1562@2	NA|NA|NA	I	PFAM Squalene phytoene synthase
MAG.T21.18_01293	926562.Oweho_3541	2.2e-154	552.4	Cryomorphaceae	crtI		1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37	ko:K10027,ko:K20611	ko00906,ko01100,ko01110,map00906,map01100,map01110		R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000				Bacteria	1HWP8@117743,2PAC9@246874,4NF7K@976,COG1233@1,COG1233@2	NA|NA|NA	Q	Flavin containing amine oxidoreductase
MAG.T21.18_01294	927658.AJUM01000017_gene3118	5.6e-33	147.5	Marinilabiliaceae	sigR_3			ko:K03088					ko00000,ko03021				Bacteria	2FNH5@200643,3XJ3Z@558415,4NMM3@976,COG1595@1,COG1595@2	NA|NA|NA	K	ECF sigma factor
MAG.T21.18_01297	714943.Mucpa_1462	5e-112	411.4	Sphingobacteriia	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0166,iSB619.SA_RS08370	Bacteria	1IQU2@117747,4NES8@976,COG0285@1,COG0285@2	NA|NA|NA	H	Belongs to the folylpolyglutamate synthase family
MAG.T21.18_01298	926562.Oweho_1778	5.4e-08	65.1	Flavobacteriia				ko:K03646,ko:K03832					ko00000,ko02000	2.C.1.1,2.C.1.2			Bacteria	1HX6B@117743,4NG4I@976,COG0810@1,COG0810@2	NA|NA|NA	M	TonB family domain protein
MAG.T21.18_01299	1168034.FH5T_19545	5.8e-22	110.5	Bacteroidia	exbD			ko:K03559					ko00000,ko02000	1.A.30.2.1			Bacteria	2FRY4@200643,4NNI6@976,COG0848@1,COG0848@2	NA|NA|NA	U	Transport energizing protein, ExbD TolR family
MAG.T21.18_01300	385682.AFSL01000064_gene1720	1.1e-63	250.0	Marinilabiliaceae	exbB			ko:K03561					ko00000,ko02000	1.A.30.2.1			Bacteria	2FNG0@200643,3XIUJ@558415,4NFIX@976,COG0811@1,COG0811@2	NA|NA|NA	U	MotA/TolQ/ExbB proton channel family
MAG.T21.18_01301	1151061.CAJY01000017_gene250	7.1e-159	567.0	Actinobacteria	gdhA2		1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GKXG@201174,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
MAG.T21.18_01302	1168034.FH5T_20310	4.6e-87	328.2	Bacteroidia	anmK		2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100		R08555	RC00397,RC00746	ko00000,ko00001,ko01000				Bacteria	2FQSQ@200643,4NFZU@976,COG2377@1,COG2377@2	NA|NA|NA	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MAG.T21.18_01303	929556.Solca_3491	3.1e-180	637.9	Sphingobacteriia	bcd		1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212		R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000				Bacteria	1IPN4@117747,4NEHA@976,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
MAG.T21.18_01304	1279009.ADICEAN_00921	2.5e-43	182.6	Cytophagia				ko:K01991	ko02026,map02026				ko00000,ko00001,ko02000	1.B.18			Bacteria	47VPS@768503,4NQV1@976,COG1596@1,COG1596@2	NA|NA|NA	M	Polysaccharide biosynthesis/export protein
MAG.T21.18_01305	1237149.C900_00335	9.5e-120	438.0	Cytophagia	wzc	GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576		ko:K16692					ko00000,ko01000,ko01001				Bacteria	47JQC@768503,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2	NA|NA|NA	DM	TIGRFAM capsular exopolysaccharide family
MAG.T21.18_01306	1237149.C900_00336	1.5e-93	350.1	Cytophagia	rfbX			ko:K03328					ko00000	2.A.66.2			Bacteria	47QZ9@768503,4NI21@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis C-terminal domain
MAG.T21.18_01307	1237149.C900_00337	2.5e-90	339.3	Cytophagia													Bacteria	28MJC@1,2ZAVX@2,47Q3J@768503,4NP81@976	NA|NA|NA		
MAG.T21.18_01308	1392498.JQLH01000001_gene571	2.6e-66	259.2	Maribacter													Bacteria	1I0UB@117743,2PHZ2@252356,4NK0K@976,COG1216@1,COG1216@2	NA|NA|NA	S	Psort location Cytoplasmic, score
MAG.T21.18_01310	1185876.BN8_06375	2.4e-66	260.8	Cytophagia													Bacteria	47NUN@768503,4NJDV@976,COG4625@1,COG4625@2	NA|NA|NA	E	PFAM Di-glucose binding within endoplasmic reticulum
MAG.T21.18_01311	762982.HMPREF9442_02458	4.7e-57	228.4	Bacteroidia			5.1.3.26	ko:K19997					ko00000,ko01000				Bacteria	2FNQG@200643,4PHT4@976,COG0451@1,COG0451@2	NA|NA|NA	M	COG0451 Nucleoside-diphosphate-sugar
MAG.T21.18_01312	1227739.Hsw_2797	5.8e-53	214.5	Cytophagia	wecG		2.4.1.187	ko:K05946	ko05111,map05111				ko00000,ko00001,ko01000,ko01003		GT26		Bacteria	47NEK@768503,4NJGT@976,COG1922@1,COG1922@2	NA|NA|NA	M	Belongs to the glycosyltransferase 26 family
MAG.T21.18_01313	1121904.ARBP01000024_gene6668	4.7e-88	331.6	Cytophagia				ko:K03606	ko05111,map05111				ko00000,ko00001				Bacteria	47N5W@768503,4NER4@976,COG2148@1,COG2148@2	NA|NA|NA	M	sugar transferase
MAG.T21.18_01314	983544.Lacal_0344	9.9e-23	112.5	Flavobacteriia	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02968	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I3XI@117743,4NSB1@976,COG0268@1,COG0268@2	NA|NA|NA	J	Binds directly to 16S ribosomal RNA
MAG.T21.18_01315	929562.Emtol_2898	4.2e-68	264.6	Cytophagia	radC			ko:K03630					ko00000				Bacteria	47KTY@768503,4NFBF@976,COG2003@1,COG2003@2	NA|NA|NA	E	Belongs to the UPF0758 family
MAG.T21.18_01316	1487923.DP73_14530	1.7e-103	382.9	Peptococcaceae	wecB		5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1TQZT@1239,247N7@186801,263DZ@186807,COG0381@1,COG0381@2	NA|NA|NA	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAG.T21.18_01317	926562.Oweho_3334	5.2e-59	235.3	Cryomorphaceae													Bacteria	1HWXT@117743,2PAVE@246874,4NF79@976,COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
MAG.T21.18_01318	1168034.FH5T_04905	5.3e-34	151.8	Bacteroidia													Bacteria	2FT4P@200643,4NQN5@976,COG5653@1,COG5653@2	NA|NA|NA	M	Protein involved in cellulose biosynthesis
MAG.T21.18_01319	755732.Fluta_2237	3.3e-70	271.6	Cryomorphaceae	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000			iSB619.SA_RS11010	Bacteria	1HX32@117743,2PBNQ@246874,4NFZM@976,COG0035@1,COG0035@2	NA|NA|NA	F	Uracil phosphoribosyltransferase
MAG.T21.18_01321	1288963.ADIS_0699	6.3e-43	181.0	Cytophagia	yjjG	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723,ko:K20862	ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120	M00125	R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_4614	Bacteria	47Q1Q@768503,4NM66@976,COG1011@1,COG1011@2	NA|NA|NA	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E
MAG.T21.18_01323	649349.Lbys_2286	2.3e-63	248.8	Cytophagia	psd		4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	47MWN@768503,4NFU1@976,COG0688@1,COG0688@2	NA|NA|NA	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MAG.T21.18_01324	762968.HMPREF9441_00402	6.9e-60	238.0	Bacteroidia													Bacteria	2FPXN@200643,4NGSA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
MAG.T21.18_01326	1233950.IW22_18365	1.4e-15	91.3	Bacteroidetes													Bacteria	4PNEQ@976,COG4733@1,COG4733@2	NA|NA|NA	S	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_01327	1227739.Hsw_4095	1.3e-33	150.2	Cytophagia	cdsA		2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	47KPM@768503,4NIPM@976,COG4589@1,COG4589@2	NA|NA|NA	S	Belongs to the CDS family
MAG.T21.18_01329	1137281.D778_01045	1.2e-229	802.7	Flavobacteriia	ftsH			ko:K03798		M00742			ko00000,ko00002,ko01000,ko01002,ko03110				Bacteria	1HXSC@117743,4NF0E@976,COG0465@1,COG0465@2	NA|NA|NA	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAG.T21.18_01330	1286632.P278_02830	1e-31	142.9	Flavobacteriia	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	1I1ZH@117743,4NSKK@976,COG0799@1,COG0799@2	NA|NA|NA	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAG.T21.18_01331	1158294.JOMI01000007_gene513	7.8e-28	131.0	Bacteroidia	birA		6.3.4.15	ko:K03523,ko:K03524	ko00780,ko01100,ko02010,map00780,map01100,map02010	M00581,M00582	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.88.1,2.A.88.2			Bacteria	2FMM7@200643,4NHCH@976,COG0340@1,COG0340@2	NA|NA|NA	H	biotin acetyl-CoA-carboxylase ligase
MAG.T21.18_01332	1313421.JHBV01000026_gene419	2.2e-12	77.4	Sphingobacteriia	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02914	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IU87@117747,4NUTV@976,COG0230@1,COG0230@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL34 family
MAG.T21.18_01333	1185876.BN8_06096	2.7e-37	162.5	Cytophagia													Bacteria	47PDP@768503,4PM2G@976,COG0596@1,COG0596@2	NA|NA|NA	S	alpha/beta hydrolase fold
MAG.T21.18_01335	313606.M23134_08062	3.6e-25	122.5	Bacteroidetes													Bacteria	4PMES@976,COG4977@1,COG4977@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.18_01336	1250232.JQNJ01000001_gene3553	4.4e-48	199.1	Flavobacteriia			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1HZV1@117743,4NNBR@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.18_01337	1121373.KB903654_gene1654	1.4e-30	139.4	Cytophagia													Bacteria	47QQ9@768503,4NMVC@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.18_01338	592029.DDD_2891	1.1e-51	209.9	Flavobacteriia	fic			ko:K04095					ko00000,ko03036				Bacteria	1HYYF@117743,4NM5F@976,COG2184@1,COG2184@2	NA|NA|NA	D	Fic/DOC family
MAG.T21.18_01340	926562.Oweho_1705	0.0	1131.3	Cryomorphaceae	mfd		2.4.1.129,3.4.16.4	ko:K03723,ko:K05365	ko00550,ko03420,map00550,map03420		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011,ko03400		GT51		Bacteria	1HWS4@117743,2PA9W@246874,4NEPA@976,COG1197@1,COG1197@2	NA|NA|NA	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAG.T21.18_01341	1313421.JHBV01000039_gene2715	3.5e-95	355.1	Sphingobacteriia	yneE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K08994					ko00000,ko02000	1.A.46.2			Bacteria	1IVEN@117747,4NGJ0@976,COG3781@1,COG3781@2	NA|NA|NA	S	Bestrophin, RFP-TM, chloride channel
MAG.T21.18_01342	512565.AMIS_58080	2.4e-33	149.4	Bacteria	wcfH												Bacteria	COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
MAG.T21.18_01344	1158294.JOMI01000007_gene395	1.3e-116	426.0	Bacteroidia	vanW			ko:K18346	ko01502,ko02020,map01502,map02020	M00651			ko00000,ko00001,ko00002,ko01504				Bacteria	2FTAQ@200643,4NMJR@976,COG2720@1,COG2720@2	NA|NA|NA	V	VanW like protein
MAG.T21.18_01345	946077.W5A_08047	1.1e-14	88.2	Bacteroidetes													Bacteria	4PNC5@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01346	946077.W5A_08047	1.9e-14	87.4	Bacteroidetes													Bacteria	4PNC5@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01347	946077.W5A_08047	3.1e-17	96.7	Bacteroidetes													Bacteria	4PNC5@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01348	946077.W5A_08047	6.3e-13	82.4	Bacteroidetes													Bacteria	4PNC5@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01349	1535422.ND16A_1503	2e-75	289.3	Gammaproteobacteria	mscS			ko:K03442					ko00000,ko02000	1.A.23.2			Bacteria	1N596@1224,1RQZP@1236,COG0668@1,COG0668@2	NA|NA|NA	M	Mechanosensitive Ion channel
MAG.T21.18_01350	485918.Cpin_5873	4.6e-32	144.4	Bacteroidetes													Bacteria	4PN8K@976,COG0500@1,COG0500@2	NA|NA|NA	H	Methyltransferase domain
MAG.T21.18_01351	743722.Sph21_1488	1.1e-163	583.2	Sphingobacteriia													Bacteria	1INMD@117747,4NDZK@976,COG1538@1,COG1538@2	NA|NA|NA	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT
MAG.T21.18_01352	1392490.JHZX01000001_gene3407	0.0	1650.6	Flavobacteriia				ko:K03296					ko00000	2.A.6.2			Bacteria	1HX2H@117743,4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.18_01353	743722.Sph21_1486	1.1e-116	426.8	Sphingobacteriia	acrA			ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718			ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6			Bacteria	1IQ3F@117747,4NEXN@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.18_01355	1210884.HG799464_gene10754	2.1e-71	275.8	Planctomycetes			3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	2IZCH@203682,COG1611@1,COG1611@2	NA|NA|NA	NOU	Possible lysine decarboxylase
MAG.T21.18_01356	926549.KI421517_gene2206	1.1e-202	713.8	Cytophagia													Bacteria	47JSW@768503,4NEIE@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.18_01357	926549.KI421517_gene2207	1.1e-121	443.7	Cytophagia													Bacteria	47MBP@768503,4NH7Q@976,COG5492@1,COG5492@2	NA|NA|NA	N	domain, Protein
MAG.T21.18_01358	161528.ED21_21054	5.9e-07	63.2	Sphingomonadales													Bacteria	1MU7T@1224,2K5QE@204457,2TRVY@28211,COG2931@1,COG2931@2	NA|NA|NA	Q	Peptidase M10 serralysin C terminal
MAG.T21.18_01359	886379.AEWI01000012_gene1148	6.3e-25	120.6	Marinilabiliaceae	yqaA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	2FRY9@200643,3XK2Z@558415,4NQAX@976,COG1238@1,COG1238@2	NA|NA|NA	S	SNARE-like domain protein
MAG.T21.18_01360	313606.M23134_06790	9.7e-07	60.8	Bacteroidetes													Bacteria	2B2YN@1,31VJM@2,4NXAT@976	NA|NA|NA		
MAG.T21.18_01361	929556.Solca_0356	5.9e-179	634.0	Sphingobacteriia	purH		2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IP42@117747,4NEZD@976,COG0138@1,COG0138@2	NA|NA|NA	F	Bifunctional purine biosynthesis protein PurH
MAG.T21.18_01362	755732.Fluta_1895	1.7e-161	575.5	Cryomorphaceae	mreB			ko:K03569					ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1			Bacteria	1HXDD@117743,2PACA@246874,4NETQ@976,COG1077@1,COG1077@2	NA|NA|NA	D	TIGRFAM cell shape determining protein, MreB Mrl family
MAG.T21.18_01363	1122226.AUHX01000003_gene229	1.5e-43	183.3	Flavobacteriia	mreC			ko:K03570					ko00000,ko03036	9.B.157.1			Bacteria	1HWJM@117743,4NF14@976,COG1792@1,COG1792@2	NA|NA|NA	M	shape-determining protein MreC
MAG.T21.18_01364	1168289.AJKI01000011_gene653	2.6e-25	122.1	Marinilabiliaceae	mreD												Bacteria	2AFDM@1,2FPJA@200643,315DF@2,3XK2I@558415,4NQ5K@976	NA|NA|NA	S	rod shape-determining protein MreD
MAG.T21.18_01365	1121373.KB903636_gene816	6.7e-169	600.9	Cytophagia	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501				ko00000,ko00001,ko01000,ko01011			iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	Bacteria	47JSM@768503,4NE47@976,COG0768@1,COG0768@2	NA|NA|NA	M	Penicillin-binding protein, dimerisation domain
MAG.T21.18_01366	1408433.JHXV01000006_gene2631	1.3e-105	390.2	Cryomorphaceae	rodA			ko:K05837					ko00000,ko03036				Bacteria	1HXI4@117743,2PAKS@246874,4NDZD@976,COG0772@1,COG0772@2	NA|NA|NA	D	Cell cycle protein
MAG.T21.18_01367	1408473.JHXO01000001_gene2471	1.9e-87	330.5	Bacteroidia	ppiD		5.2.1.8	ko:K01802,ko:K03769,ko:K03770					ko00000,ko01000,ko03110				Bacteria	2FN8C@200643,4NDZZ@976,COG0760@1,COG0760@2	NA|NA|NA	O	peptidylprolyl isomerase
MAG.T21.18_01368	926562.Oweho_0085	1.4e-91	343.6	Cryomorphaceae	tlyC												Bacteria	1HWV0@117743,2PA4U@246874,4NG0I@976,COG1253@1,COG1253@2	NA|NA|NA	S	Transporter associated domain
MAG.T21.18_01370	1453500.AT05_10925	8e-17	94.0	Bacteroidetes	lptC			ko:K09774,ko:K11719					ko00000,ko02000	1.B.42.1			Bacteria	4NV8G@976,COG3117@1,COG3117@2	NA|NA|NA	S	Lipopolysaccharide-assembly, LptC-related
MAG.T21.18_01371	886379.AEWI01000018_gene1256	6.4e-52	211.8	Marinilabiliaceae													Bacteria	2FP0S@200643,3XJQ1@558415,4NF7U@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat protein
MAG.T21.18_01372	485917.Phep_4028	3.7e-37	162.9	Sphingobacteriia													Bacteria	1IPB7@117747,4NEP1@976,COG2067@1,COG2067@2	NA|NA|NA	I	membrane
MAG.T21.18_01373	1123277.KB893217_gene4525	8.6e-43	180.6	Cytophagia	coaX		2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000				Bacteria	47K36@768503,4NE9E@976,COG1521@1,COG1521@2	NA|NA|NA	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MAG.T21.18_01375	1185876.BN8_03731	1.4e-48	199.5	Cytophagia	yueE			ko:K06950					ko00000				Bacteria	47PQZ@768503,4NFAG@976,COG1418@1,COG1418@2	NA|NA|NA	S	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAG.T21.18_01376	485918.Cpin_0674	2.8e-46	192.6	Sphingobacteriia													Bacteria	1IPNM@117747,4NK58@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.18_01377	1124780.ANNU01000005_gene2353	1.5e-169	602.8	Cytophagia	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056	Bacteria	47K1F@768503,4NEQT@976,COG0696@1,COG0696@2	NA|NA|NA	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAG.T21.18_01378	755732.Fluta_2021	1.2e-76	294.7	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1ICPB@117743,2PBH6@246874,4PFQY@976,COG3291@1,COG3291@2	NA|NA|NA	S	Calx-beta domain
MAG.T21.18_01379	755732.Fluta_2021	5.1e-93	349.4	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1ICPB@117743,2PBH6@246874,4PFQY@976,COG3291@1,COG3291@2	NA|NA|NA	S	Calx-beta domain
MAG.T21.18_01380	1237149.C900_00754	1.8e-187	662.1	Cytophagia	dapE		3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	47JN6@768503,4NFGE@976,COG0624@1,COG0624@2	NA|NA|NA	E	PFAM Peptidase family M20 M25 M40
MAG.T21.18_01383	929556.Solca_1191	1.7e-186	659.4	Sphingobacteriia	yyaL			ko:K06888					ko00000				Bacteria	1IQ72@117747,4NFE2@976,COG1331@1,COG1331@2	NA|NA|NA	O	COG1331 Highly conserved protein containing a thioredoxin domain
MAG.T21.18_01386	445970.ALIPUT_01525	3.5e-32	145.2	Rikenellaceae	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564		ko:K14742					ko00000,ko03016				Bacteria	22UD1@171550,2FPYK@200643,4NDUR@976,COG1214@1,COG1214@2	NA|NA|NA	O	Glycoprotease family
MAG.T21.18_01387	1121904.ARBP01000028_gene1712	4.5e-56	225.7	Cytophagia	tolC			ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821			ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2			Bacteria	47M95@768503,4NEEN@976,COG1538@1,COG1538@2	NA|NA|NA	MU	PFAM Outer membrane efflux protein
MAG.T21.18_01388	1408433.JHXV01000001_gene651	8.8e-32	144.8	Cryomorphaceae													Bacteria	1ICSE@117743,2PBZT@246874,4PISD@976,COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.18_01389	926549.KI421517_gene355	0.0	1128.6	Cytophagia	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0030312,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13,2.1.1.245,2.1.1.258	ko:K00197,ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00357,M00377,M00422	R00946,R02289,R09096,R09365,R10219,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000			iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	Bacteria	47K8Q@768503,4NFRF@976,COG0646@1,COG0646@2,COG1410@1,COG1410@2	NA|NA|NA	E	Vitamin B12 dependent methionine synthase activation
MAG.T21.18_01390	926554.KI912657_gene4306	1.1e-13	82.4	Bacteria													Bacteria	2E3PF@1,32YMI@2	NA|NA|NA		
MAG.T21.18_01392	1408433.JHXV01000020_gene3552	8e-33	147.1	Cryomorphaceae				ko:K03088					ko00000,ko03021				Bacteria	1IG88@117743,2PB14@246874,4NKHT@976,COG1595@1,COG1595@2	NA|NA|NA	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family
MAG.T21.18_01393	1313421.JHBV01000046_gene248	7.2e-19	102.4	Bacteria			3.2.1.14	ko:K01183,ko:K03933	ko00520,ko01100,map00520,map01100		R01206,R02334	RC00467	ko00000,ko00001,ko01000		AA10,CBM73,GH18		Bacteria	COG3227@1,COG3227@2,COG3291@1,COG3291@2	NA|NA|NA	E	Zinc metalloprotease (Elastase)
MAG.T21.18_01395	1313421.JHBV01000016_gene5579	3.3e-294	1017.3	Sphingobacteriia	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_0688	Bacteria	1IPYP@117747,4NF2P@976,COG2987@1,COG2987@2	NA|NA|NA	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MAG.T21.18_01396	1313421.JHBV01000044_gene2943	3.5e-11	76.6	Bacteroidetes													Bacteria	2DFI2@1,2ZRXQ@2,4P736@976	NA|NA|NA		
MAG.T21.18_01397	926562.Oweho_1891	1.7e-14	84.7	Cryomorphaceae													Bacteria	1I511@117743,2E5CT@1,2PB9K@246874,3304V@2,4NUT8@976	NA|NA|NA		
MAG.T21.18_01398	869213.JCM21142_73060	3.7e-65	255.4	Cytophagia	lytG			ko:K02395,ko:K14196	ko05150,map05150				ko00000,ko00001,ko02035				Bacteria	47WJ6@768503,4NEER@976,COG1388@1,COG1388@2,COG1705@1,COG1705@2	NA|NA|NA	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAG.T21.18_01399	266748.HY04_05475	1.3e-23	115.9	Chryseobacterium	ctb			ko:K06886					ko00000				Bacteria	1IJ52@117743,3ZUM8@59732,4NQCV@976,COG2346@1,COG2346@2	NA|NA|NA	S	Bacterial-like globin
MAG.T21.18_01400	1008457.BAEX01000044_gene2840	1.6e-51	209.5	Myroides	ktrA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1HYTE@117743,47HX7@76831,4NGRQ@976,COG0569@1,COG0569@2	NA|NA|NA	P	TrkA-N domain
MAG.T21.18_01401	1249975.JQLP01000005_gene1423	7.4e-117	427.9	Flavobacteriia	ktrB			ko:K03498					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1HY9Z@117743,4NF7R@976,COG0168@1,COG0168@2	NA|NA|NA	P	potassium uptake protein, TrkH family
MAG.T21.18_01402	927658.AJUM01000037_gene2023	3.6e-34	153.7	Marinilabiliaceae													Bacteria	2FQ6V@200643,3XJUS@558415,4NHQ3@976,COG1520@1,COG1520@2	NA|NA|NA	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAG.T21.18_01403	926562.Oweho_1848	1.3e-63	249.6	Cryomorphaceae	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1HWSB@117743,2PASI@246874,4NGVR@976,COG0164@1,COG0164@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAG.T21.18_01404	1408433.JHXV01000009_gene1297	1.2e-99	370.2	Cryomorphaceae			2.4.1.349	ko:K12994					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1HZ9Z@117743,2PC6E@246874,4NETA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase Family 4
MAG.T21.18_01406	1408473.JHXO01000001_gene2296	1.4e-92	347.1	Bacteroidia													Bacteria	2G3BA@200643,4NPGZ@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
MAG.T21.18_01407	926562.Oweho_1845	1.7e-57	229.9	Cryomorphaceae			3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111				ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1			Bacteria	1I785@117743,2PAYX@246874,4NWAG@976,COG3206@1,COG3206@2	NA|NA|NA	M	Chain length determinant protein
MAG.T21.18_01408	1168034.FH5T_03520	1.1e-37	164.1	Bacteroidetes				ko:K07011,ko:K16554,ko:K20998	ko02025,ko05111,map02025,map05111				ko00000,ko00001,ko02000	8.A.3.1			Bacteria	4NSFM@976,COG3206@1,COG3206@2	NA|NA|NA	M	protein involved in exopolysaccharide biosynthesis
MAG.T21.18_01409	1408433.JHXV01000009_gene1254	1.4e-102	380.2	Cryomorphaceae	tuaE			ko:K16705					ko00000				Bacteria	1I79G@117743,2PAI6@246874,4NMYT@976,COG3307@1,COG3307@2	NA|NA|NA	M	O-Antigen ligase
MAG.T21.18_01410	1120951.AUBG01000007_gene37	1.7e-28	133.7	Flavobacteriia			3.4.21.121	ko:K07004,ko:K20755					ko00000,ko01000,ko01002				Bacteria	1HWT9@117743,4NF3C@976,COG4935@1,COG4935@2	NA|NA|NA	O	Outer membrane protein Omp28
MAG.T21.18_01412	1042375.AFPL01000016_gene23	5.9e-29	134.4	Alteromonadaceae	sigX			ko:K03088					ko00000,ko03021				Bacteria	1RHKM@1224,1S48U@1236,46B93@72275,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70, region 4
MAG.T21.18_01413	313595.P700755_003235	5.2e-93	348.6	Flavobacteriia													Bacteria	1I4B1@117743,4NF1M@976,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
MAG.T21.18_01414	1168034.FH5T_15140	3.1e-181	641.7	Bacteroidia	algI			ko:K19294					ko00000				Bacteria	2FM3F@200643,4NFK5@976,COG1696@1,COG1696@2	NA|NA|NA	M	Psort location CytoplasmicMembrane, score 10.00
MAG.T21.18_01415	1168034.FH5T_15135	5.8e-76	291.6	Bacteroidia	Z012_00180		3.1.1.5	ko:K10804	ko01040,map01040				ko00000,ko00001,ko01000,ko01004				Bacteria	2FN21@200643,4NGW6@976,COG2755@1,COG2755@2	NA|NA|NA	E	COG NOG14456 non supervised orthologous group
MAG.T21.18_01416	1168034.FH5T_15130	5.3e-84	318.5	Bacteroidia	Z012_00180		3.1.1.5	ko:K10804	ko01040,map01040				ko00000,ko00001,ko01000,ko01004				Bacteria	2G37X@200643,4NHT6@976,COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
MAG.T21.18_01417	869213.JCM21142_104181	2.3e-58	233.4	Cytophagia	mltD			ko:K08307,ko:K12204					ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1			Bacteria	47KJK@768503,4NEKW@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2	NA|NA|NA	M	PFAM Transglycosylase SLT domain
MAG.T21.18_01418	483219.LILAB_23965	3.3e-30	139.4	Myxococcales													Bacteria	1REU1@1224,2X9CR@28221,2Z1T7@29,43AB0@68525,COG1835@1,COG1835@2	NA|NA|NA	I	Acyltransferase family
MAG.T21.18_01419	1121899.Q764_11630	9.4e-112	410.2	Flavobacterium	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYIB@117743,2NTIR@237,4NE01@976,COG0010@1,COG0010@2	NA|NA|NA	E	Belongs to the arginase family
MAG.T21.18_01420	755732.Fluta_1216	1.2e-46	194.9	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1HZ7Y@117743,2PBDM@246874,4NGRJ@976,COG3291@1,COG3291@2	NA|NA|NA	O	PFAM Pregnancy-associated plasma protein-A
MAG.T21.18_01422	1286632.P278_13420	6.3e-42	177.2	Flavobacteriia	ysmA			ko:K07107,ko:K12500					ko00000,ko01000,ko01004				Bacteria	1I2SF@117743,4NK6Y@976,COG0824@1,COG0824@2	NA|NA|NA	S	Thioesterase-like superfamily
MAG.T21.18_01426	1034807.FBFL15_1546	6.5e-12	77.4	Flavobacterium													Bacteria	1HZZE@117743,2NVDA@237,4NFKA@976,COG1002@1,COG1002@2	NA|NA|NA	V	Type II restriction enzyme, methylase subunits
MAG.T21.18_01432	1499967.BAYZ01000091_gene3427	1.4e-25	125.2	unclassified Bacteria													Bacteria	2NRSS@2323,COG4249@1,COG4249@2	NA|NA|NA	S	Peptidase C13 family
MAG.T21.18_01433	1353276.JADR01000001_gene279	5.4e-144	517.7	Flavobacteriia	hisS		6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1HX0E@117743,4NE8N@976,COG0124@1,COG0124@2	NA|NA|NA	J	histidyl-tRNA synthetase
MAG.T21.18_01434	1203611.KB894544_gene2217	1.8e-164	585.9	Rikenellaceae	hutH		4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000				Bacteria	22UX6@171550,2FMCF@200643,4NE0D@976,COG2986@1,COG2986@2	NA|NA|NA	E	Histidine ammonia-lyase
MAG.T21.18_01435	1035193.HMPREF9073_02024	3.4e-27	128.6	Capnocytophaga			3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000				Bacteria	1ERUP@1016,1IJBZ@117743,4PKKR@976,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha/beta hydrolase family
MAG.T21.18_01436	755732.Fluta_2885	0.0	1176.8	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1IGQE@117743,2PBJ6@246874,4PI0H@976,COG3291@1,COG3291@2	NA|NA|NA	S	PKD domain
MAG.T21.18_01437	1223410.KN050846_gene1382	1.4e-57	231.1	Flavobacteriia													Bacteria	1I1UJ@117743,4NN21@976,COG2885@1,COG2885@2,COG5295@1,COG5295@2	NA|NA|NA	UW	arginyl-trna synthetase
MAG.T21.18_01438	926562.Oweho_3015	3.7e-170	604.7	Cryomorphaceae	glcD		1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130		R00475	RC00042	ko00000,ko00001,ko01000				Bacteria	1HXIK@117743,2PB4N@246874,4NEK3@976,COG0277@1,COG0277@2	NA|NA|NA	C	FAD linked oxidases, C-terminal domain
MAG.T21.18_01439	641526.ADIWIN_1390	3.7e-56	225.3	Flavobacteriia	merR			ko:K21089,ko:K21972,ko:K22491	ko02026,map02026				ko00000,ko00001,ko03000				Bacteria	1HWT4@117743,4NERC@976,COG0789@1,COG0789@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.18_01440	1406840.Q763_12715	1.4e-149	536.6	Flavobacterium													Bacteria	1IKCE@117743,2DBTS@1,2NY7R@237,2ZB0P@2,4NGP7@976	NA|NA|NA	S	Domain of unknown function (DUF4397)
MAG.T21.18_01441	755732.Fluta_1892	5.4e-231	807.7	Bacteroidetes				ko:K06880					ko00000,ko01000,ko01504				Bacteria	4PP0J@976,COG1520@1,COG1520@2,COG2312@1,COG2312@2,COG4386@1,COG4386@2	NA|NA|NA	E	CotH kinase protein
MAG.T21.18_01442	1121904.ARBP01000002_gene6681	1.5e-31	142.9	Bacteroidetes													Bacteria	4NQEI@976,COG2318@1,COG2318@2	NA|NA|NA	S	Protein of unknown function (DUF1572)
MAG.T21.18_01444	743722.Sph21_1609	2.3e-165	588.6	Sphingobacteriia	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141		ko:K02600					ko00000,ko03009,ko03021				Bacteria	1IQJC@117747,4NFGA@976,COG0195@1,COG0195@2	NA|NA|NA	K	Participates in both transcription termination and antitermination
MAG.T21.18_01445	1122971.BAME01000007_gene979	6.4e-20	104.0	Porphyromonadaceae	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576		ko:K09748					ko00000,ko03009				Bacteria	22Y41@171551,2FSM9@200643,4NQ32@976,COG0779@1,COG0779@2	NA|NA|NA	S	Required for maturation of 30S ribosomal subunits
MAG.T21.18_01447	1122176.KB903546_gene1028	6.6e-143	514.6	Bacteria	manA5		3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024		R01332	RC00467	ko00000,ko00001,ko01000,ko04147		GH26,GH29		Bacteria	COG2133@1,COG2133@2	NA|NA|NA	G	pyrroloquinoline quinone binding
MAG.T21.18_01448	485918.Cpin_0141	9.5e-64	250.4	Sphingobacteriia	ycbX	GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754		ko:K07140					ko00000				Bacteria	1IPTU@117747,4NG33@976,COG3217@1,COG3217@2	NA|NA|NA	S	MOSC domain containing protein
MAG.T21.18_01449	700598.Niako_3010	7.5e-69	267.3	Sphingobacteriia	CP_0807			ko:K09125					ko00000				Bacteria	1IQJP@117747,4NFP3@976,COG1738@1,COG1738@2	NA|NA|NA	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MAG.T21.18_01450	1123248.KB893315_gene3130	6.6e-29	134.0	Sphingobacteriia			2.3.1.128	ko:K03790					ko00000,ko01000,ko03009				Bacteria	1IYVQ@117747,4NV0H@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.18_01452	1392488.JHZY01000004_gene2667	2.3e-152	545.4	Leeuwenhoekiella	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1HY1I@117743,2XIG9@283735,4NF19@976,COG0162@1,COG0162@2	NA|NA|NA	J	tRNA synthetases class I (W and Y)
MAG.T21.18_01453	926562.Oweho_1982	1.3e-97	363.2	Cryomorphaceae				ko:K00666					ko00000,ko01000,ko01004				Bacteria	1IJB2@117743,2PA5N@246874,4NDXK@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	Acyl-protein synthetase, LuxE
MAG.T21.18_01454	1453500.AT05_05240	1.2e-18	99.8	Flavobacteriia													Bacteria	1IC33@117743,2A5B1@1,30U0G@2,4PHGE@976	NA|NA|NA		
MAG.T21.18_01455	1237149.C900_04445	1.2e-145	523.5	Cytophagia	phoU_1			ko:K03324					ko00000,ko02000	2.A.58.2			Bacteria	47N3M@768503,4NHMY@976,COG1283@1,COG1283@2	NA|NA|NA	P	Na+/Pi-cotransporter
MAG.T21.18_01456	755732.Fluta_2306	9.2e-75	287.3	Cryomorphaceae	phoR		2.7.13.3	ko:K07636	ko02020,map02020	M00434			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1HXVZ@117743,2PA7P@246874,4NETP@976,COG5002@1,COG5002@2	NA|NA|NA	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_01457	984262.SGRA_1027	4.6e-97	361.7	Sphingobacteriia	nucA		3.1.3.5	ko:K01081,ko:K01173,ko:K06931	ko00230,ko00240,ko00760,ko01100,ko01110,ko04210,map00230,map00240,map00760,map01100,map01110,map04210		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000,ko03029				Bacteria	1IY0Z@117747,4NFYJ@976,COG1864@1,COG1864@2,COG4085@1,COG4085@2	NA|NA|NA	F	DNA/RNA non-specific endonuclease
MAG.T21.18_01458	485918.Cpin_0710	3.6e-61	242.3	Sphingobacteriia													Bacteria	1IX57@117747,4NFRJ@976,COG0707@1,COG0707@2	NA|NA|NA	M	Glycosyl transferase family 1
MAG.T21.18_01459	1035197.HMPREF9999_01801	2.2e-61	242.3	Alloprevotella	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.297,2.1.1.33	ko:K02493,ko:K03439			R10806	RC00003,RC03279	ko00000,ko01000,ko03012,ko03016				Bacteria	1WCTY@1283313,2FN8Z@200643,4NG4V@976,COG0220@1,COG0220@2	NA|NA|NA	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAG.T21.18_01460	927677.ALVU02000001_gene2013	1.2e-48	200.3	Synechocystis			3.5.2.6	ko:K17838,ko:K22351	ko01501,map01501		R06363	RC01499	ko00000,ko00001,ko01000,ko01504				Bacteria	1GBHT@1117,1H6NW@1142,COG2602@1,COG2602@2	NA|NA|NA	V	Penicillin binding protein transpeptidase domain
MAG.T21.18_01461	1122605.KB893628_gene4449	3.3e-33	147.9	Sphingobacteriia	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	2.1.1.63	ko:K00567,ko:K07443					ko00000,ko01000,ko03400				Bacteria	1IT8P@117747,4NQ34@976,COG3695@1,COG3695@2	NA|NA|NA	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain
MAG.T21.18_01463	1122176.KB903587_gene4484	2.7e-114	419.5	Sphingobacteriia			3.4.11.10	ko:K05994					ko00000,ko01000,ko01002				Bacteria	1IPRF@117747,4NENF@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.18_01464	1380600.AUYN01000012_gene2971	2.9e-55	224.6	Bacteroidetes													Bacteria	4NQIK@976,COG0464@1,COG0464@2	NA|NA|NA	O	growth
MAG.T21.18_01465	1279009.ADICEAN_00227	1e-08	66.6	Cytophagia													Bacteria	2DTRU@1,33MEF@2,47XTM@768503,4NYGC@976	NA|NA|NA		
MAG.T21.18_01466	1166018.FAES_3879	6.4e-102	378.6	Cytophagia				ko:K03640					ko00000,ko02000	2.C.1.2			Bacteria	47K1N@768503,4NE6G@976,COG2885@1,COG2885@2	NA|NA|NA	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein
MAG.T21.18_01467	1121890.AUDO01000023_gene2867	1.4e-64	253.4	Flavobacterium													Bacteria	1HWKC@117743,2NT6M@237,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	membrane
MAG.T21.18_01468	313606.M23134_02237	0.0	1223.4	Cytophagia				ko:K14274,ko:K20276	ko00040,ko02024,map00040,map02024		R02427	RC00713	ko00000,ko00001,ko01000				Bacteria	47N8F@768503,4NJ9V@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2,COG3386@1,COG3386@2,COG4932@1,COG4932@2	NA|NA|NA	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_01470	485918.Cpin_2394	1.7e-30	140.2	Bacteroidetes													Bacteria	4NKYH@976,COG3266@1,COG3266@2	NA|NA|NA	S	domain, Protein
MAG.T21.18_01471	1317122.ATO12_01115	5.2e-192	677.6	Aquimarina	fdsB		1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1			Bacteria	1HYZ9@117743,2YIWZ@290174,4NFB5@976,COG1894@1,COG1894@2	NA|NA|NA	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
MAG.T21.18_01472	700598.Niako_0889	1.8e-10	73.9	Sphingobacteriia													Bacteria	1IYX8@117747,2EPP0@1,33H9M@2,4NXT6@976	NA|NA|NA		
MAG.T21.18_01473	1408433.JHXV01000020_gene3566	1.1e-40	174.1	Bacteria													Bacteria	COG4886@1,COG4886@2	NA|NA|NA	S	regulation of response to stimulus
MAG.T21.18_01474	755732.Fluta_1300	6.1e-134	484.2	Cryomorphaceae	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	Bacteria	1HWNW@117743,2PAA5@246874,4NF33@976,COG0508@1,COG0508@2	NA|NA|NA	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MAG.T21.18_01475	1408813.AYMG01000014_gene1686	0.0	1092.8	Sphingobacteriia	sucA	GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732	Bacteria	1IQYB@117747,4NEU9@976,COG0567@1,COG0567@2	NA|NA|NA	C	2-oxoglutarate dehydrogenase, E1
MAG.T21.18_01478	1313421.JHBV01000037_gene2908	9.8e-44	185.3	Bacteroidetes													Bacteria	4NRQS@976,COG1404@1,COG1404@2,COG3209@1,COG3209@2	NA|NA|NA	M	Beta-galactosidase
MAG.T21.18_01479	313606.M23134_05848	3e-66	258.8	Cytophagia	yfcH			ko:K07071					ko00000				Bacteria	47KA1@768503,4NINM@976,COG1090@1,COG1090@2	NA|NA|NA	S	PFAM NAD dependent epimerase dehydratase family
MAG.T21.18_01480	762903.Pedsa_1243	1.9e-66	259.6	Sphingobacteriia	idsA		2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1INSC@117747,4NEGQ@976,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
MAG.T21.18_01481	755732.Fluta_0901	8.3e-130	469.9	Cryomorphaceae	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0334	Bacteria	1HWWH@117743,2PAM5@246874,4NE1U@976,COG1209@1,COG1209@2	NA|NA|NA	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MAG.T21.18_01482	1168034.FH5T_06920	4.2e-187	661.8	Bacteroidia				ko:K07003					ko00000				Bacteria	2G2YH@200643,4NE0M@976,COG1033@1,COG1033@2	NA|NA|NA	S	Sterol-sensing domain of SREBP cleavage-activation
MAG.T21.18_01483	926562.Oweho_2016	4.7e-125	455.7	Bacteroidetes													Bacteria	4NFFZ@976,COG4775@1,COG4775@2	NA|NA|NA	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAG.T21.18_01484	1123276.KB893245_gene1333	2.4e-128	465.3	Cytophagia													Bacteria	47K59@768503,4NGWY@976,COG0535@1,COG0535@2	NA|NA|NA	C	Radical SAM
MAG.T21.18_01485	1121957.ATVL01000008_gene4538	5.2e-36	158.3	Cytophagia													Bacteria	47JGU@768503,4NJB3@976,COG2067@1,COG2067@2	NA|NA|NA	I	Protein of unknown function (DUF2490)
MAG.T21.18_01486	1168289.AJKI01000002_gene2616	2.2e-54	218.8	Marinilabiliaceae	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576		ko:K02838					ko00000,ko03012				Bacteria	2FPZE@200643,3XJMJ@558415,4NF95@976,COG0233@1,COG0233@2	NA|NA|NA	J	Ribosome recycling factor
MAG.T21.18_01487	929556.Solca_3454	1.3e-96	359.4	Sphingobacteriia	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100		R00158	RC00002	ko00000,ko00001,ko01000			iSB619.SA_RS06240	Bacteria	1IPN7@117747,4NE8Z@976,COG0528@1,COG0528@2	NA|NA|NA	F	Catalyzes the reversible phosphorylation of UMP to UDP
MAG.T21.18_01488	755732.Fluta_2476	5.1e-21	107.1	Cryomorphaceae	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065		ko:K02357					ko00000,ko03012,ko03029				Bacteria	1HWYJ@117743,2PATD@246874,4NF03@976,COG0264@1,COG0264@2	NA|NA|NA	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAG.T21.18_01489	865937.Gilli_0558	6.5e-36	159.8	Gillisia													Bacteria	1HWKJ@117743,2P5SV@244698,4PKD0@976,COG1520@1,COG1520@2,COG2304@1,COG2304@2,COG3391@1,COG3391@2	NA|NA|NA	U	C-terminal domain of CHU protein family
MAG.T21.18_01490	485918.Cpin_3624	2.2e-56	226.1	Sphingobacteriia													Bacteria	1IP9M@117747,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_01491	869213.JCM21142_41900	5.9e-79	302.4	Cytophagia				ko:K03641					ko00000,ko02000	2.C.1.2			Bacteria	47K1N@768503,4NE6G@976,COG0823@1,COG0823@2,COG2885@1,COG2885@2,COG3291@1,COG3291@2	NA|NA|NA	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein
MAG.T21.18_01492	755732.Fluta_2423	2.4e-212	746.1	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1I7ZV@117743,2PAMN@246874,4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	S	PFAM PKD domain
MAG.T21.18_01493	1408433.JHXV01000018_gene3849	9.3e-51	207.6	Cryomorphaceae				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	1ICQ4@117743,2PBNE@246874,4NIU4@976,COG2067@1,COG2067@2	NA|NA|NA	I	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_01494	1408433.JHXV01000018_gene3850	2.3e-86	327.0	Cryomorphaceae													Bacteria	1IMQT@117743,2PBGH@246874,4P0PU@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.18_01495	1211813.CAPH01000018_gene1083	3.9e-61	241.5	Rikenellaceae	purN	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	2.1.2.2,3.4.13.21,6.3.2.6,6.3.4.13	ko:K05995,ko:K11175,ko:K13713	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04144,R04325,R04326,R04591	RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	22U8N@171550,2FQTC@200643,4NEXW@976,COG0299@1,COG0299@2,COG3340@1,COG3340@2	NA|NA|NA	E	Belongs to the peptidase S51 family
MAG.T21.18_01496	1121904.ARBP01000003_gene6287	8.2e-69	267.3	Cytophagia													Bacteria	47P8R@768503,4NF28@976,COG0668@1,COG0668@2	NA|NA|NA	M	Mechanosensitive ion channel
MAG.T21.18_01497	572547.Amico_1281	9.4e-83	313.9	Synergistetes	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830		ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	3TARI@508458,COG0598@1,COG0598@2	NA|NA|NA	P	Mediates influx of magnesium ions
MAG.T21.18_01498	1227739.Hsw_3802	5.5e-41	174.5	Cytophagia													Bacteria	47PYR@768503,4NMX5@976,COG2197@1,COG2197@2	NA|NA|NA	KT	helix_turn_helix, Lux Regulon
MAG.T21.18_01500	1250005.PHEL85_3394	5.6e-47	196.1	Flavobacteriia													Bacteria	1HX4T@117743,4NI65@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_01501	1250005.PHEL85_3394	1.2e-46	194.9	Flavobacteriia													Bacteria	1HX4T@117743,4NI65@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_01502	471854.Dfer_2050	2.7e-221	776.5	Cytophagia													Bacteria	47S7V@768503,4NKIR@976,COG2831@1,COG2831@2,COG2931@1,COG2931@2	NA|NA|NA	Q	SMART Integrin alpha beta-propellor repeat protein
MAG.T21.18_01503	376686.Fjoh_3246	0.0	1096.3	Flavobacterium				ko:K13735	ko05100,map05100				ko00000,ko00001				Bacteria	1IMWQ@117743,2NVU6@237,4PCAF@976,COG2373@1,COG2373@2	NA|NA|NA	S	CARDB
MAG.T21.18_01505	1453500.AT05_03125	1.2e-181	642.9	Flavobacteriia	lysA		4.1.1.19,4.1.1.20	ko:K01585,ko:K01586	ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00133,M00525,M00526,M00527	R00451,R00566	RC00299	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS18870	Bacteria	1HXKA@117743,4NFHV@976,COG0019@1,COG0019@2	NA|NA|NA	E	decarboxylase
MAG.T21.18_01506	992406.RIA_1448	6.8e-147	526.9	Flavobacteriia	dys		2.5.1.46	ko:K00809					ko00000,ko01000				Bacteria	1HXQG@117743,4NEZ0@976,COG1899@1,COG1899@2	NA|NA|NA	O	Deoxyhypusine synthase
MAG.T21.18_01507	1107311.Q767_02555	2.6e-07	62.0	Flavobacterium													Bacteria	1I4E2@117743,2CJFR@1,2P0G1@237,32RQT@2,4NSHX@976	NA|NA|NA		
MAG.T21.18_01508	639030.JHVA01000001_gene1099	8e-30	136.7	Acidobacteriia				ko:K06991					ko00000				Bacteria	2JMWG@204432,3Y7MG@57723,COG3565@1,COG3565@2	NA|NA|NA	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAG.T21.18_01510	1408433.JHXV01000002_gene476	2.6e-80	305.4	Cryomorphaceae													Bacteria	1IJGW@117743,2PAZ2@246874,4PKQ7@976,COG1974@1,COG1974@2	NA|NA|NA	K	Helix-turn-helix
MAG.T21.18_01511	411154.GFO_2160	1.7e-43	182.6	Flavobacteriia													Bacteria	1I2ID@117743,4NMXS@976,COG1502@1,COG1502@2	NA|NA|NA	I	ORF6N domain
MAG.T21.18_01512	1270193.JARP01000002_gene540	4.7e-32	144.8	Flavobacterium													Bacteria	1IKR8@117743,2P0UV@237,4PM3Z@976,COG3646@1,COG3646@2	NA|NA|NA	S	ORF6N domain
MAG.T21.18_01513	391596.PBAL39_15864	3.1e-32	146.4	Sphingobacteriia			3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	1ITFP@117747,4NGGJ@976,COG0793@1,COG0793@2	NA|NA|NA	M	Peptidase family S41
MAG.T21.18_01514	926562.Oweho_1440	2.1e-204	719.2	Cryomorphaceae													Bacteria	1HZ14@117743,2PAXQ@246874,4NF6J@976,COG0507@1,COG0507@2	NA|NA|NA	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
MAG.T21.18_01515	1120966.AUBU01000001_gene751	2.4e-20	104.8	Bacteroidetes													Bacteria	2CCSR@1,32RSC@2,4NT8X@976	NA|NA|NA	S	23S rRNA-intervening sequence protein
MAG.T21.18_01518	1122179.KB890435_gene931	1.7e-129	470.3	Bacteroidetes													Bacteria	4NI4U@976,COG5337@1,COG5337@2	NA|NA|NA	M	COG5337 Spore coat assembly protein
MAG.T21.18_01519	391587.KAOT1_12237	2.1e-56	226.9	Flavobacteriia													Bacteria	1HXXS@117743,4NHPR@976,COG1520@1,COG1520@2	NA|NA|NA	G	Arylsulfotransferase (ASST)
MAG.T21.18_01520	1408433.JHXV01000010_gene537	8.2e-257	893.6	Cryomorphaceae	nagA		3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000				Bacteria	1HX49@117743,2PA7Q@246874,4NET8@976,COG1472@1,COG1472@2,COG1680@1,COG1680@2	NA|NA|NA	GV	PFAM Glycosyl hydrolase family 3 N terminal domain
MAG.T21.18_01521	755732.Fluta_0888	5.9e-30	139.4	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1ICSF@117743,2PBZU@246874,4PI05@976,COG3291@1,COG3291@2	NA|NA|NA	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_01522	714943.Mucpa_6158	2.7e-22	111.7	Sphingobacteriia				ko:K07107					ko00000,ko01000				Bacteria	1ITE5@117747,4NQ3I@976,COG0824@1,COG0824@2	NA|NA|NA	S	Thioesterase-like superfamily
MAG.T21.18_01523	755732.Fluta_2695	3.9e-56	224.9	Cryomorphaceae													Bacteria	1HY5Y@117743,2C8XG@1,2PBHM@246874,2Z7PK@2,4NEU8@976	NA|NA|NA	S	Protein of unknown function (DUF4197)
MAG.T21.18_01524	292564.Cyagr_2258	1.2e-62	246.5	Cyanobium													Bacteria	1GNA1@1117,22TIR@167375,COG3510@1,COG3510@2	NA|NA|NA	V	Cephalosporin hydroxylase
MAG.T21.18_01525	706436.HMPREF9074_08364	3.5e-78	298.5	Capnocytophaga	udp		2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000				Bacteria	1EQK6@1016,1HYDH@117743,4NG5S@976,COG2820@1,COG2820@2	NA|NA|NA	F	Phosphorylase family
MAG.T21.18_01528	468059.AUHA01000002_gene10	1.2e-22	112.5	Sphingobacteriia	hpf			ko:K05808,ko:K05809					ko00000,ko03009				Bacteria	1ITNJ@117747,4NUME@976,COG1544@1,COG1544@2	NA|NA|NA	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein
MAG.T21.18_01529	1121481.AUAS01000003_gene4015	4.1e-63	248.4	Cytophagia	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03733,ko:K04763					ko00000,ko03036				Bacteria	47JJY@768503,4NGQW@976,COG4974@1,COG4974@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
MAG.T21.18_01530	1392489.JPOL01000002_gene2562	1.1e-13	82.0	Leeuwenhoekiella	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02970	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I50J@117743,2XJJ7@283735,4NUPV@976,COG0828@1,COG0828@2	NA|NA|NA	J	Ribosomal protein S21
MAG.T21.18_01531	485918.Cpin_1288	2.1e-160	572.0	Sphingobacteriia	yngJ	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410,ko:K18244	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212		R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000				Bacteria	1IP19@117747,4NEHA@976,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
MAG.T21.18_01532	714943.Mucpa_4340	3.6e-51	208.0	Sphingobacteriia	apt		2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100		R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147				Bacteria	1IS3F@117747,4NP7K@976,COG0503@1,COG0503@2	NA|NA|NA	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAG.T21.18_01533	504472.Slin_1689	2.6e-42	179.5	Cytophagia	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	47KXV@768503,4NK4K@976,COG1555@1,COG1555@2	NA|NA|NA	L	Helix-hairpin-helix motif
MAG.T21.18_01535	1121897.AUGO01000001_gene1467	6.8e-245	853.2	Flavobacterium				ko:K03308					ko00000	2.A.22.4,2.A.22.5			Bacteria	1IFBS@117743,2NVEG@237,4NGQ5@976,COG0733@1,COG0733@2	NA|NA|NA	S	Sodium:neurotransmitter symporter family
MAG.T21.18_01536	926562.Oweho_1411	5.2e-90	337.8	Cryomorphaceae	rmlD		1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXB2@117743,2PAPS@246874,4NE3K@976,COG1091@1,COG1091@2	NA|NA|NA	M	Male sterility protein
MAG.T21.18_01537	755732.Fluta_3396	7.9e-52	211.1	Cryomorphaceae				ko:K12976					ko00000,ko01000,ko01005				Bacteria	1ICQ3@117743,2PBMQ@246874,4PJ16@976,COG3637@1,COG3637@2	NA|NA|NA	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MAG.T21.18_01538	1267211.KI669560_gene2122	7.6e-41	173.7	Sphingobacteriia	spoU		2.1.1.185	ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	1IS2Z@117747,4NM8C@976,COG0566@1,COG0566@2	NA|NA|NA	J	SpoU rRNA Methylase family
MAG.T21.18_01539	385682.AFSL01000009_gene2423	5.8e-267	927.2	Marinilabiliaceae	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K03555	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	2FMFA@200643,3XJCK@558415,4NEGB@976,COG0249@1,COG0249@2	NA|NA|NA	L	MutS domain II
MAG.T21.18_01540	1408473.JHXO01000001_gene2016	1.3e-41	178.7	Bacteroidetes													Bacteria	4P3PY@976,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein, YfhO
MAG.T21.18_01543	755732.Fluta_0839	4.7e-137	494.2	Cryomorphaceae	pdhB		1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2753	Bacteria	1HWQC@117743,2PADS@246874,4NE4N@976,COG0022@1,COG0022@2	NA|NA|NA	C	Transketolase, pyrimidine binding domain
MAG.T21.18_01544	755732.Fluta_0840	3.7e-78	298.1	Cryomorphaceae	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114		ko:K03521					ko00000				Bacteria	1HX74@117743,2PAQ1@246874,4NFWB@976,COG2086@1,COG2086@2	NA|NA|NA	C	Electron transfer flavoprotein domain
MAG.T21.18_01545	1408433.JHXV01000015_gene1753	5e-96	357.8	Cryomorphaceae	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575		ko:K03522					ko00000,ko04147				Bacteria	1HX9P@117743,2PAQ3@246874,4NFSE@976,COG2025@1,COG2025@2	NA|NA|NA	C	Electron transfer flavoprotein domain
MAG.T21.18_01546	1408433.JHXV01000015_gene1754	2e-50	205.7	Cryomorphaceae	yqdE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K03617,ko:K08999					ko00000				Bacteria	1HXCB@117743,2PAS5@246874,4NGSW@976,COG1259@1,COG1259@2	NA|NA|NA	S	Bifunctional nuclease
MAG.T21.18_01547	1121912.AUHD01000006_gene1376	8.2e-156	557.0	Flavobacteriia	yeiM			ko:K03317					ko00000	2.A.41			Bacteria	1HY0T@117743,4NEYN@976,COG1972@1,COG1972@2	NA|NA|NA	F	nucleoside transporter
MAG.T21.18_01548	880070.Cycma_1622	5.9e-12	78.6	Bacteria													Bacteria	2C9Y4@1,33CSC@2	NA|NA|NA		
MAG.T21.18_01549	1121405.dsmv_2071	4.3e-134	485.0	Desulfobacterales	algI												Bacteria	1MUXN@1224,2MJC8@213118,2WMEK@28221,42MIR@68525,COG1696@1,COG1696@2	NA|NA|NA	M	MBOAT, membrane-bound O-acyltransferase family
MAG.T21.18_01551	1121288.AULL01000013_gene1687	1.1e-107	397.1	Chryseobacterium	clcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03281					ko00000	2.A.49			Bacteria	1HWJE@117743,3ZQX2@59732,4NFCF@976,COG0038@1,COG0038@2	NA|NA|NA	P	Chloride channel protein
MAG.T21.18_01552	1313421.JHBV01000032_gene1682	8.5e-20	105.1	Bacteroidetes				ko:K12057					ko00000,ko02044	3.A.7.11.1			Bacteria	4NNXC@976,COG0526@1,COG0526@2,COG1404@1,COG1404@2,COG3291@1,COG3291@2	NA|NA|NA	CO	Outer membrane protein Omp28
MAG.T21.18_01553	926562.Oweho_0762	7e-64	251.9	Cryomorphaceae	norB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114	1.7.2.5	ko:K03973,ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000,ko02048,ko03000	3.D.4.10			Bacteria	1HX01@117743,2PAXN@246874,4NG3T@976,COG1983@1,COG1983@2,COG3256@1,COG3256@2	NA|NA|NA	KT	PspC domain
MAG.T21.18_01554	1223410.KN050846_gene888	9.3e-38	162.9	Flavobacteriia	padR			ko:K10947					ko00000,ko03000				Bacteria	1I2SA@117743,4NSI4@976,COG1695@1,COG1695@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.18_01555	1123008.KB905694_gene1671	5e-31	140.6	Porphyromonadaceae													Bacteria	22YGK@171551,2AMB7@1,2FU3Q@200643,31C6A@2,4NQ8I@976	NA|NA|NA		
MAG.T21.18_01556	926569.ANT_06550	9.7e-25	121.7	Bacteria				ko:K14340					ko00000,ko01000,ko01003				Bacteria	COG5305@1,COG5305@2	NA|NA|NA		
MAG.T21.18_01557	926562.Oweho_0933	1.4e-229	802.4	Cryomorphaceae	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020					ko00000,ko01000				Bacteria	1HXQY@117743,2PAKK@246874,4NES5@976,COG0488@1,COG0488@2	NA|NA|NA	S	TIGRFAM ATP-binding cassette protein, ChvD family
MAG.T21.18_01558	404380.Gbem_2933	6.7e-100	371.7	Deltaproteobacteria													Bacteria	1NNJ6@1224,2WKWJ@28221,42PBD@68525,COG0457@1,COG0457@2	NA|NA|NA	M	Tetratricopeptide TPR_2 repeat protein
MAG.T21.18_01559	1123400.KB904752_gene845	1.5e-37	165.2	Proteobacteria													Bacteria	1QWWH@1224,COG2834@1,COG2834@2,COG3420@1,COG3420@2	NA|NA|NA	P	Beta-L-arabinofuranosidase, GH127
MAG.T21.18_01560	1392490.JHZX01000001_gene3278	4.4e-18	101.3	Flavobacteriia				ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	1I3GX@117743,4NHCC@976,COG5295@1,COG5295@2	NA|NA|NA	UW	ubiquitin
MAG.T21.18_01561	1122179.KB890452_gene4652	8.3e-84	318.9	Bacteria													Bacteria	COG3292@1,COG3292@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_01562	1122605.KB893645_gene991	3.4e-48	198.4	Sphingobacteriia	degU												Bacteria	1J05Y@117747,4NNQH@976,COG2197@1,COG2197@2	NA|NA|NA	T	helix_turn_helix, Lux Regulon
MAG.T21.18_01564	1123035.ARLA01000019_gene2645	6.5e-106	391.7	Psychroflexus													Bacteria	1HZ43@117743,4C2D7@83612,4NDUD@976,COG5276@1,COG5276@2	NA|NA|NA	S	LVIVD repeat
MAG.T21.18_01565	279714.FuraDRAFT_2946	5.9e-130	470.3	Neisseriales	thyA		2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000				Bacteria	1MUBD@1224,2KPIK@206351,2VIIR@28216,COG0207@1,COG0207@2	NA|NA|NA	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAG.T21.18_01566	391625.PPSIR1_14870	3.2e-47	194.9	Myxococcales	folA		1.5.1.3	ko:K00287,ko:K18589	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1RH0P@1224,2WQA3@28221,2YVD7@29,42UMS@68525,COG0262@1,COG0262@2	NA|NA|NA	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAG.T21.18_01567	755732.Fluta_0947	2.3e-41	176.0	Cryomorphaceae													Bacteria	1IF21@117743,2A7NQ@1,2PBZY@246874,30WKT@2,4PA0D@976	NA|NA|NA		
MAG.T21.18_01568	861299.J421_2095	4.6e-43	182.2	Gemmatimonadetes			2.7.13.3	ko:K08082	ko02020,map02020	M00493			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1ZUX6@142182,COG2972@1,COG2972@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_01569	1317122.ATO12_04795	1.2e-58	233.4	Aquimarina													Bacteria	1IIN5@117743,2YKJJ@290174,4NEAH@976,COG3279@1,COG3279@2	NA|NA|NA	T	LytTr DNA-binding domain
MAG.T21.18_01570	1380600.AUYN01000010_gene883	4.6e-69	268.5	Flavobacteriia													Bacteria	1I0QJ@117743,4NEYK@976,COG0457@1,COG0457@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.18_01571	926549.KI421517_gene2980	1.9e-187	662.9	Cytophagia	mca			ko:K22136					ko00000				Bacteria	47KXK@768503,4NE9K@976,COG2120@1,COG2120@2	NA|NA|NA	G	PFAM GlcNAc-PI de-N-acetylase
MAG.T21.18_01572	574376.BAMA_10675	8e-48	197.2	Bacillus	alkD												Bacteria	1V4WB@1239,1ZGCX@1386,4HFXG@91061,COG4912@1,COG4912@2	NA|NA|NA	L	DNA alkylation repair
MAG.T21.18_01573	1519464.HY22_09355	3.7e-40	172.2	Bacteria													Bacteria	2ZBGR@2,arCOG09742@1	NA|NA|NA		
MAG.T21.18_01574	1519464.HY22_13125	1.2e-52	214.5	Bacteria			3.4.17.18	ko:K05996					ko00000,ko01000,ko01002				Bacteria	COG0737@1,COG0737@2,COG1520@1,COG1520@2	NA|NA|NA	F	nucleotide catabolic process
MAG.T21.18_01575	159087.Daro_3836	5.5e-233	813.5	Rhodocyclales	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110		R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000				Bacteria	1MUBF@1224,2KV5J@206389,2VH5H@28216,COG0376@1,COG0376@2	NA|NA|NA	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MAG.T21.18_01576	1286632.P278_24860	0.0	1271.9	Flavobacteriia	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_0027,iPC815.YPO0475	Bacteria	1HX3Y@117743,4NEYT@976,COG0060@1,COG0060@2	NA|NA|NA	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAG.T21.18_01577	755732.Fluta_1722	3e-39	169.1	Cryomorphaceae	dksA			ko:K06204	ko02026,map02026				ko00000,ko00001,ko03000,ko03009,ko03021				Bacteria	1I1Y4@117743,2PAZZ@246874,4NNID@976,COG1734@1,COG1734@2	NA|NA|NA	T	Molecular chaperone DnaK
MAG.T21.18_01578	869213.JCM21142_1647	2e-54	219.2	Cytophagia	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	47MEJ@768503,4NEZN@976,COG0597@1,COG0597@2	NA|NA|NA	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAG.T21.18_01580	755732.Fluta_1913	5.7e-130	470.7	Cryomorphaceae	asd		1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1523	Bacteria	1HYS3@117743,2PAC1@246874,4NE4V@976,COG0136@1,COG0136@2	NA|NA|NA	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAG.T21.18_01581	755732.Fluta_1911	1.2e-155	557.4	Cryomorphaceae													Bacteria	1I8HX@117743,2PAB4@246874,4NHM6@976,COG4288@1,COG4288@2	NA|NA|NA	S	Lamin Tail Domain
MAG.T21.18_01582	1120951.AUBG01000003_gene2787	2.4e-168	598.6	Flavobacteriia	gabT	GO:0003674,GO:0003824,GO:0003867,GO:0008483,GO:0016740,GO:0016769	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007			iHN637.CLJU_RS10045	Bacteria	1HY4F@117743,4NFWF@976,COG0160@1,COG0160@2	NA|NA|NA	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.18_01583	1250278.JQNQ01000001_gene3043	8.4e-123	446.8	Flavobacteriia	amiE												Bacteria	1HY7N@117743,4NEME@976,COG0388@1,COG0388@2	NA|NA|NA	S	Pfam Carbon-nitrogen hydrolase
MAG.T21.18_01584	1123234.AUKI01000011_gene1125	1.3e-36	159.5	Flavobacteriia				ko:K06996					ko00000				Bacteria	1I2JA@117743,4NMFV@976,COG3324@1,COG3324@2	NA|NA|NA	S	Glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.18_01585	926562.Oweho_2220	4.8e-197	694.1	Cryomorphaceae	lysS		6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1HXY4@117743,2PABR@246874,4NDZN@976,COG1190@1,COG1190@2	NA|NA|NA	J	PFAM tRNA synthetases class II (D, K and N)
MAG.T21.18_01587	1356852.N008_03135	4.5e-32	144.8	Cytophagia													Bacteria	2B5D2@1,31Y78@2,47SKV@768503,4NHI5@976	NA|NA|NA		
MAG.T21.18_01588	1408433.JHXV01000006_gene2623	1.5e-74	286.6	Cryomorphaceae	pgi		5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000				Bacteria	1I8JM@117743,2PANV@246874,4NIX0@976,COG2222@1,COG2222@2	NA|NA|NA	G	PFAM Bacterial phospho-glucose isomerase C-terminal region
MAG.T21.18_01589	1121481.AUAS01000014_gene2326	3.3e-84	318.2	Cytophagia	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100		R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000				Bacteria	47KKV@768503,4NE14@976,COG0321@1,COG0321@2	NA|NA|NA	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
MAG.T21.18_01590	643867.Ftrac_2199	2.2e-77	296.2	Cytophagia	nylB												Bacteria	47NMR@768503,4NEVS@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.18_01591	313606.M23134_07467	4.4e-33	147.5	Cytophagia													Bacteria	2AGNU@1,316WB@2,47RK1@768503,4NSNZ@976	NA|NA|NA		
MAG.T21.18_01592	755732.Fluta_1219	1.1e-66	260.0	Cryomorphaceae	wlaX			ko:K07501					ko00000				Bacteria	1HY85@117743,2PATH@246874,4NECH@976,COG3298@1,COG3298@2	NA|NA|NA	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
MAG.T21.18_01593	1408433.JHXV01000006_gene2690	2.5e-59	237.3	Bacteroidetes													Bacteria	4NUWQ@976,COG1287@1,COG1287@2	NA|NA|NA	S	oligosaccharyl transferase activity
MAG.T21.18_01594	1227739.Hsw_0103	8.6e-48	197.2	Cytophagia													Bacteria	47RH9@768503,4PP1X@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.18_01595	313606.M23134_07914	7.7e-97	360.1	Cytophagia													Bacteria	47KDC@768503,4NF0S@976,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.18_01596	886293.Sinac_0651	1e-19	105.1	Planctomycetes													Bacteria	2A5J9@1,2J2SZ@203682,30U9K@2	NA|NA|NA		
MAG.T21.18_01597	1408433.JHXV01000008_gene221	2.4e-14	87.4	Cryomorphaceae													Bacteria	1IMQ5@117743,2PB6F@246874,4NXNF@976,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAG.T21.18_01598	1122176.KB903565_gene3368	5.8e-99	367.1	Sphingobacteriia	scoB		2.8.3.5	ko:K01027,ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650		R00410	RC00014	ko00000,ko00001,ko01000				Bacteria	1IQBC@117747,4NG9J@976,COG2057@1,COG2057@2	NA|NA|NA	I	PFAM Coenzyme A transferase
MAG.T21.18_01599	1408433.JHXV01000008_gene221	5.4e-35	156.0	Cryomorphaceae													Bacteria	1IMQ5@117743,2PB6F@246874,4NXNF@976,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAG.T21.18_01600	1122176.KB903565_gene3367	4.9e-104	384.0	Sphingobacteriia	scoA		2.8.3.5	ko:K01027,ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650		R00410	RC00014	ko00000,ko00001,ko01000				Bacteria	1IQP0@117747,4NF3T@976,COG1788@1,COG1788@2	NA|NA|NA	I	PFAM Coenzyme A transferase
MAG.T21.18_01601	760192.Halhy_4524	2.6e-81	309.7	Sphingobacteriia	peaA		1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120		R00606	RC00189	ko00000,ko00001,ko01000				Bacteria	1IP2H@117747,4NEEJ@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_01602	714943.Mucpa_3213	2.6e-83	315.8	Sphingobacteriia	holB		2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1INPG@117747,4NEYF@976,COG0470@1,COG0470@2	NA|NA|NA	L	COG2812 DNA polymerase III, gamma tau subunits
MAG.T21.18_01603	742817.HMPREF9449_02253	8.2e-136	490.3	Porphyromonadaceae	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	22WBD@171551,2FM2Q@200643,4NFW2@976,COG0126@1,COG0126@2	NA|NA|NA	F	Belongs to the phosphoglycerate kinase family
MAG.T21.18_01604	1227739.Hsw_0498	4e-08	66.2	Bacteria													Bacteria	COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase activity
MAG.T21.18_01605	1168034.FH5T_03555	1.6e-19	102.8	Bacteroidia	cvpA			ko:K03558					ko00000				Bacteria	2G2B1@200643,4NRG9@976,COG1286@1,COG1286@2	NA|NA|NA	S	Colicin V production protein
MAG.T21.18_01606	398720.MED217_00300	9.5e-29	132.9	Leeuwenhoekiella													Bacteria	1I1Z8@117743,29D8R@1,2XJH9@283735,3006P@2,4NNGD@976	NA|NA|NA		
MAG.T21.18_01607	1408433.JHXV01000015_gene1774	6.4e-13	80.5	Cryomorphaceae													Bacteria	1IMTB@117743,2A5H4@1,2PC40@246874,30U7A@2,4PFFN@976	NA|NA|NA		
MAG.T21.18_01608	767031.HMPREF9137_1220	2.6e-52	212.2	Bacteroidia	ppiA		5.2.1.8	ko:K03768					ko00000,ko01000,ko03110				Bacteria	2G31W@200643,4NMKP@976,COG0652@1,COG0652@2	NA|NA|NA	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAG.T21.18_01609	1408433.JHXV01000015_gene1775	1e-118	433.3	Cryomorphaceae	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1HWWV@117743,2PAHY@246874,4NF8I@976,COG0016@1,COG0016@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAG.T21.18_01610	1356852.N008_02895	8.1e-96	357.5	Cytophagia			1.3.99.38	ko:K21401					ko00000,ko01000				Bacteria	47U5U@768503,4NKR8@976,COG0644@1,COG0644@2	NA|NA|NA	C	FAD binding domain
MAG.T21.18_01611	938709.AUSH02000073_gene1750	9.2e-79	301.2	Bacteroidetes													Bacteria	4PKMZ@976,COG3291@1,COG3291@2	NA|NA|NA	G	TIGRFAM Por secretion system C-terminal sorting domain
MAG.T21.18_01612	929556.Solca_3233	2e-104	386.0	Sphingobacteriia	pdxA		1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP2F@117747,4NEUR@976,COG1995@1,COG1995@2	NA|NA|NA	H	Belongs to the PdxA family
MAG.T21.18_01613	1408473.JHXO01000001_gene2292	2.4e-118	432.6	Bacteroidia	pepA		3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	2FMS1@200643,4NDWT@976,COG0260@1,COG0260@2	NA|NA|NA	E	Cytosol aminopeptidase family, catalytic domain
MAG.T21.18_01614	1408433.JHXV01000014_gene3628	8.3e-189	667.5	Cryomorphaceae													Bacteria	1I840@117743,2PBAC@246874,4NFCW@976,COG3291@1,COG3291@2	NA|NA|NA	Q	Fibronectin type 3 domain
MAG.T21.18_01615	980584.AFPB01000124_gene2360	2e-55	222.2	unclassified Flavobacteriaceae	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000			iYO844.BSU23270	Bacteria	1HYXC@117743,406A9@61432,4NHI8@976,COG0307@1,COG0307@2	NA|NA|NA	H	Lumazine binding domain
MAG.T21.18_01616	1279009.ADICEAN_03476	3.3e-158	565.5	Cytophagia	pepN1												Bacteria	47JW1@768503,4NG5Q@976,COG0308@1,COG0308@2	NA|NA|NA	E	Peptidase M1, membrane alanine aminopeptidase
MAG.T21.18_01617	755732.Fluta_1600	8.9e-117	426.8	Cryomorphaceae	metF		1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000				Bacteria	1HX0S@117743,2PAI3@246874,4NDY0@976,COG0685@1,COG0685@2	NA|NA|NA	C	Methylenetetrahydrofolate reductase
MAG.T21.18_01618	755732.Fluta_1778	5.1e-108	399.1	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1IG7A@117743,2PBJ3@246874,4PI0B@976,COG3291@1,COG3291@2,COG4935@1,COG4935@2	NA|NA|NA	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_01620	1349822.NSB1T_02110	2.2e-46	192.2	Porphyromonadaceae				ko:K03088					ko00000,ko03021				Bacteria	22Y21@171551,2FSRW@200643,4NQCH@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.18_01621	1469557.JSWF01000027_gene1944	2.9e-38	167.2	Flavobacteriia			3.4.21.72	ko:K01347					ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1IJT5@117743,4PMHH@976,COG1361@1,COG1361@2,COG4886@1,COG4886@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.18_01625	755732.Fluta_1658	7.5e-146	523.5	Cryomorphaceae	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	1HY3S@117743,2PAC2@246874,4NEXT@976,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAG.T21.18_01626	1408433.JHXV01000001_gene721	1.5e-24	120.6	Cryomorphaceae													Bacteria	1IMQ8@117743,2PB7I@246874,4PJHB@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01629	929562.Emtol_0587	7.5e-18	96.3	Cytophagia	pspE			ko:K03972					ko00000				Bacteria	47SAY@768503,4NSD1@976,COG0607@1,COG0607@2	NA|NA|NA	P	PFAM Rhodanese-like domain
MAG.T21.18_01630	1185876.BN8_02686	4.8e-21	107.5	Cytophagia	glpE												Bacteria	47RW1@768503,4NUPH@976,COG0607@1,COG0607@2	NA|NA|NA	P	Rhodanese Homology Domain
MAG.T21.18_01631	1120968.AUBX01000015_gene3509	1.1e-08	67.0	Bacteroidetes													Bacteria	2ETUA@1,33MBM@2,4NYNV@976	NA|NA|NA	S	Outer membrane protein beta-barrel domain
MAG.T21.18_01632	1122176.KB903531_gene3015	1.1e-47	197.6	Bacteroidetes													Bacteria	4NNWF@976,COG0657@1,COG0657@2	NA|NA|NA	I	COG0657 Esterase lipase
MAG.T21.18_01633	1313301.AUGC01000004_gene2435	1.1e-75	290.4	Bacteroidetes			3.4.24.40	ko:K01406	ko01503,map01503				ko00000,ko00001,ko01000,ko01002				Bacteria	4NEGS@976,COG2356@1,COG2356@2,COG2373@1,COG2373@2	NA|NA|NA	L	Nuclease, EndA NucM family
MAG.T21.18_01635	1121875.KB907549_gene1896	1.1e-90	340.1	Flavobacteriia													Bacteria	1IIKA@117743,4NJ5X@976,COG0604@1,COG0604@2	NA|NA|NA	C	Zinc-binding dehydrogenase
MAG.T21.18_01636	1432055.GLUCORHAEAF1_11940	2.1e-46	192.2	Rhodospirillales	yvdD		3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	1RD59@1224,2JSHV@204441,2U5DP@28211,COG1611@1,COG1611@2	NA|NA|NA	S	Belongs to the LOG family
MAG.T21.18_01637	313606.M23134_06902	7.4e-82	312.4	Bacteria													Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_01638	1123057.P872_12595	5.6e-11	74.7	Cytophagia													Bacteria	47PGW@768503,4NRJW@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.18_01639	1123277.KB893243_gene268	3.3e-18	98.2	Cytophagia													Bacteria	47YB7@768503,4NW2E@976,COG0810@1,COG0810@2	NA|NA|NA	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.18_01641	471854.Dfer_3577	7.6e-08	63.9	Bacteria													Bacteria	2EDF6@1,337BG@2	NA|NA|NA		
MAG.T21.18_01645	1048983.EL17_20265	5.1e-15	87.4	Cytophagia													Bacteria	2DS7U@1,33EX4@2,47SMW@768503,4NZKK@976	NA|NA|NA	S	Protein of unknown function (DUF2442)
MAG.T21.18_01646	1187851.A33M_0936	4.7e-14	83.6	Alphaproteobacteria													Bacteria	1N8K7@1224,2C5EY@1,2UGJ4@28211,32YQJ@2	NA|NA|NA	S	Domain of unknown function (DUF4160)
MAG.T21.18_01647	1408433.JHXV01000010_gene597	6.2e-279	966.8	Cryomorphaceae	pdhB		1.2.4.4,2.2.1.1	ko:K00615,ko:K11381	ko00030,ko00280,ko00640,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00280,map00640,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00036,M00165,M00167	R01067,R01641,R01830,R06590,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00032,RC00226,RC00571,RC00627,RC01560,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1HYUM@117743,2PA86@246874,4NE4A@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2	NA|NA|NA	C	Transketolase, pyrimidine binding domain
MAG.T21.18_01648	1122604.JONR01000008_gene2267	1.7e-140	507.3	Xanthomonadales													Bacteria	1NC9X@1224,1T3U3@1236,1XDBR@135614,COG0784@1,COG0784@2,COG3829@1,COG3829@2,COG5002@1,COG5002@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
MAG.T21.18_01651	1107311.Q767_07755	7.5e-91	341.7	Flavobacterium													Bacteria	1HX9D@117743,2P01U@237,4NF0B@976,COG2133@1,COG2133@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.18_01652	118168.MC7420_6700	1.3e-104	386.7	Oscillatoriales	sufS												Bacteria	1G15D@1117,1H76J@1150,COG0520@1,COG0520@2	NA|NA|NA	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.18_01653	358681.BBR47_04160	2.6e-29	134.8	Paenibacillaceae	algA												Bacteria	1V9DQ@1239,26YM0@186822,4HJK4@91061,COG0662@1,COG0662@2	NA|NA|NA	G	Cupin domain
MAG.T21.18_01654	471854.Dfer_2045	1.1e-79	303.5	Cytophagia													Bacteria	47PYM@768503,4NGJR@976,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
MAG.T21.18_01655	946077.W5A_06910	2.5e-58	232.3	Flavobacteriia				ko:K07090					ko00000				Bacteria	1HWXF@117743,4NFTT@976,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.18_01656	1121904.ARBP01000002_gene6745	2e-96	359.4	Cytophagia				ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111				ko00000,ko00001,ko03000				Bacteria	47JY7@768503,4NFB1@976,COG0664@1,COG0664@2,COG0745@1,COG0745@2	NA|NA|NA	K	Transcriptional regulator, Crp Fnr family
MAG.T21.18_01657	471854.Dfer_5317	1.4e-87	330.1	Cytophagia													Bacteria	47JUV@768503,4NG0Y@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.18_01658	1469557.JSWF01000014_gene2450	1.3e-21	109.8	Flavobacteriia	cdoA		1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100		R00893	RC00404	ko00000,ko00001,ko01000				Bacteria	1I45S@117743,4NSCH@976,COG5553@1,COG5553@2	NA|NA|NA	S	Cysteine dioxygenase type I
MAG.T21.18_01659	1158182.KB905021_gene667	5.2e-09	67.0	Gammaproteobacteria	copZ			ko:K07213	ko04978,map04978				ko00000,ko00001				Bacteria	1N81B@1224,1SD0H@1236,COG2608@1,COG2608@2	NA|NA|NA	P	Heavy-metal-associated domain
MAG.T21.18_01660	1121859.KB890739_gene2461	3.8e-44	184.9	Cytophagia				ko:K01420,ko:K10716					ko00000,ko02000,ko03000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6			Bacteria	47M33@768503,4NFIS@976,COG0664@1,COG0664@2	NA|NA|NA	K	PFAM Bacterial regulatory proteins, crp family
MAG.T21.18_01661	391598.FBBAL38_12760	1.4e-21	109.4	Flavobacteriia	glpE												Bacteria	1I51Q@117743,4NUPH@976,COG0607@1,COG0607@2	NA|NA|NA	P	rhodanese-related sulfurtransferase
MAG.T21.18_01662	743722.Sph21_3592	6e-31	140.2	Sphingobacteriia	trxA			ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1ITPA@117747,4PKQI@976,COG0526@1,COG0526@2	NA|NA|NA	O	Thioredoxin
MAG.T21.18_01663	1086011.HJ01_00039	1.3e-21	109.0	Flavobacterium				ko:K03972					ko00000				Bacteria	1I4FW@117743,2NX6I@237,4NSD1@976,COG0607@1,COG0607@2	NA|NA|NA	P	Rhodanese Homology Domain
MAG.T21.18_01664	679937.Bcop_1820	3.1e-12	77.4	Bacteroidaceae	yibN		2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122		R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000				Bacteria	2FUKK@200643,4AS9C@815,4NXGV@976,COG0607@1,COG0607@2	NA|NA|NA	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAG.T21.18_01665	313603.FB2170_17341	9.2e-16	89.0	Maribacter													Bacteria	1I507@117743,2DI4K@1,2PHTD@252356,3020V@2,4NV1J@976	NA|NA|NA	S	Protein of unknown function (DUF2892)
MAG.T21.18_01666	929562.Emtol_0396	1.3e-209	735.7	Cytophagia	blh		3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	47KD4@768503,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2	NA|NA|NA	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase
MAG.T21.18_01667	1250278.JQNQ01000001_gene3497	1e-45	190.3	Flavobacteriia	budA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660		R02948	RC00812	ko00000,ko00001,ko01000				Bacteria	1HX22@117743,4NKWJ@976,COG3527@1,COG3527@2	NA|NA|NA	Q	Alpha-acetolactate decarboxylase
MAG.T21.18_01668	755732.Fluta_3722	2.4e-62	245.0	Cryomorphaceae	dps	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K04047					ko00000,ko03036				Bacteria	1I1BH@117743,2PAXB@246874,4NQDD@976,COG0783@1,COG0783@2	NA|NA|NA	P	DNA-binding ferritin-like protein (Oxidative damage protectant)
MAG.T21.18_01669	1121904.ARBP01000002_gene7147	4.8e-43	181.4	Cytophagia	braZ			ko:K09792					ko00000				Bacteria	47QDS@768503,4NF84@976,COG2836@1,COG2836@2	NA|NA|NA	S	Cytochrome C biogenesis protein transmembrane region
MAG.T21.18_01670	1120965.AUBV01000012_gene1505	9.9e-15	86.7	Cytophagia	ccoH			ko:K09926					ko00000				Bacteria	47RV1@768503,4PPZ3@976,COG3198@1,COG3198@2	NA|NA|NA	S	FixH
MAG.T21.18_01671	1121904.ARBP01000002_gene7145	6.5e-151	540.8	Cytophagia	ccoG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	47KT1@768503,4NFDN@976,COG0348@1,COG0348@2	NA|NA|NA	C	TIGRFAM cytochrome c oxidase accessory protein
MAG.T21.18_01672	1107311.Q767_04210	3.5e-49	202.6	Flavobacterium	ccoP			ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156			ko00000,ko00001,ko00002	3.D.4.3			Bacteria	1HZ3Y@117743,2NSUX@237,4NFMJ@976,COG2010@1,COG2010@2	NA|NA|NA	C	cytochrome c oxidase
MAG.T21.18_01673	1227266.HMPREF1551_02254	2e-07	61.2	Capnocytophaga	ccoQ												Bacteria	1ESDZ@1016,1I51Y@117743,2E7S7@1,3327D@2,4NUQB@976	NA|NA|NA	S	PFAM Cbb3-type cytochrome oxidase component FixQ
MAG.T21.18_01674	1123248.KB893386_gene1898	0.0	1094.0	Sphingobacteriia	ccoO	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404,ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156			ko00000,ko00001,ko00002,ko01000	3.D.4.3		iIT341.HP0144,iIT341.HP0145	Bacteria	1IP6D@117747,4NEGM@976,COG2993@1,COG2993@2,COG3278@1,COG3278@2	NA|NA|NA	C	Belongs to the heme-copper respiratory oxidase family
MAG.T21.18_01676	1120999.JONM01000023_gene3164	1.4e-22	112.1	Neisseriales	yggU			ko:K09131					ko00000				Bacteria	1MZ4E@1224,2KRZB@206351,2VWDY@28216,COG1872@1,COG1872@2	NA|NA|NA	S	Belongs to the UPF0235 family
MAG.T21.18_01677	1239962.C943_00016	3.9e-43	181.4	Cytophagia													Bacteria	47XS3@768503,4NMPI@976,COG2335@1,COG2335@2	NA|NA|NA	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.
MAG.T21.18_01678	1089547.KB913013_gene4638	1.1e-51	210.3	Cytophagia	nosY			ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2			Bacteria	47KSX@768503,4NGGR@976,COG1277@1,COG1277@2	NA|NA|NA	S	ABC-2 family transporter protein
MAG.T21.18_01679	929556.Solca_1780	5.8e-50	204.5	Sphingobacteriia	nosF			ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2			Bacteria	1IPBT@117747,4NG9T@976,COG1131@1,COG1131@2	NA|NA|NA	V	ABC-type multidrug transport system ATPase component
MAG.T21.18_01680	471854.Dfer_0695	7.6e-100	370.9	Cytophagia	nosD			ko:K07218					ko00000				Bacteria	47KEF@768503,4NEGT@976,COG3420@1,COG3420@2	NA|NA|NA	P	Periplasmic copper-binding protein (NosD)
MAG.T21.18_01681	1550091.JROE01000002_gene574	3.9e-19	101.3	Sphingobacteriia	nosL			ko:K19342					ko00000				Bacteria	1IYSP@117747,4NVVP@976,COG4314@1,COG4314@2	NA|NA|NA	C	NosL
MAG.T21.18_01682	1089547.KB913013_gene4641	1.3e-49	203.0	Cytophagia	nosL			ko:K19342					ko00000				Bacteria	47NSZ@768503,4NIPU@976,COG4314@1,COG4314@2	NA|NA|NA	C	lipoprotein involved in nitrous oxide reduction
MAG.T21.18_01683	760192.Halhy_5487	1.2e-93	349.4	Sphingobacteriia	nosZ	GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234	1.7.2.4,1.9.3.1	ko:K00376,ko:K02275	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00529	R00081,R02804	RC00016,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6			Bacteria	1IQ1B@117747,4NFNE@976,COG4263@1,COG4263@2	NA|NA|NA	C	PFAM Cytochrome C oxidase subunit II, periplasmic domain
MAG.T21.18_01684	755732.Fluta_2233	1.7e-16	92.4	Cryomorphaceae			3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025		R00191	RC00296	ko00000,ko00001,ko01000				Bacteria	1ICTH@117743,2PC3S@246874,4PFBM@976,COG2146@1,COG2146@2	NA|NA|NA	P	nitrite reductase [NAD(P)H] activity
MAG.T21.18_01686	1408433.JHXV01000020_gene3544	0.0	1100.9	Cryomorphaceae													Bacteria	1IKD4@117743,2PA9C@246874,4NTQD@976,COG1629@1,COG4771@2	NA|NA|NA	P	Carboxypeptidase regulatory-like domain
MAG.T21.18_01687	1408433.JHXV01000022_gene3142	0.0	1101.3	Cryomorphaceae													Bacteria	1I891@117743,2E09V@1,2PA81@246874,32VXB@2,4NY12@976	NA|NA|NA		
MAG.T21.18_01688	1408433.JHXV01000020_gene3546	2.8e-79	302.4	Cryomorphaceae													Bacteria	1I8GR@117743,2PAP2@246874,4NWE8@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.18_01689	860228.Ccan_20680	2.3e-49	201.8	Capnocytophaga	greA			ko:K03624					ko00000,ko03021				Bacteria	1EQJG@1016,1I18I@117743,4NNH6@976,COG0782@1,COG0782@2	NA|NA|NA	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAG.T21.18_01690	880526.KE386488_gene1884	9.4e-41	172.9	Rikenellaceae	hit			ko:K02503					ko00000,ko04147				Bacteria	22UGW@171550,2FSRY@200643,4NQ4X@976,COG0537@1,COG0537@2	NA|NA|NA	FG	HIT domain
MAG.T21.18_01691	641524.ADICYQ_5941	5.7e-53	214.2	Cytophagia	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	47PA6@768503,4NDV6@976,COG0817@1,COG0817@2	NA|NA|NA	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MAG.T21.18_01692	485918.Cpin_1244	2.5e-34	152.9	Sphingobacteriia	mprF			ko:K07027					ko00000,ko02000	4.D.2			Bacteria	1IP3F@117747,4NI8Y@976,COG0392@1,COG0392@2	NA|NA|NA	S	Lysylphosphatidylglycerol synthase TM region
MAG.T21.18_01693	929556.Solca_3226	9.1e-36	157.9	Sphingobacteriia													Bacteria	1IPRP@117747,4NG9C@976,COG1215@1,COG1215@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.18_01694	926562.Oweho_2902	3.7e-21	107.8	Cryomorphaceae													Bacteria	1I1XK@117743,2PB63@246874,4NT9M@976,COG0629@1,COG0629@2	NA|NA|NA	L	Domain of unknown function (DUF3127)
MAG.T21.18_01695	1408433.JHXV01000015_gene1787	3.3e-98	365.2	Cryomorphaceae													Bacteria	1HWZA@117743,2PA79@246874,4NF4H@976,COG1853@1,COG1853@2	NA|NA|NA	S	Flavin reductase like domain
MAG.T21.18_01697	755732.Fluta_0357	1e-94	354.0	Cryomorphaceae	tig			ko:K03545					ko00000				Bacteria	1HX7I@117743,2PABE@246874,4NE99@976,COG0544@1,COG0544@2	NA|NA|NA	O	PFAM Bacterial trigger factor protein (TF)
MAG.T21.18_01698	1408433.JHXV01000011_gene2092	2.6e-94	351.7	Cryomorphaceae	clpP		3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	1HWT0@117743,2PA6J@246874,4NE20@976,COG0740@1,COG0740@2	NA|NA|NA	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAG.T21.18_01699	755732.Fluta_2301	2.9e-160	571.6	Cryomorphaceae	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575		ko:K03544	ko04112,map04112				ko00000,ko00001,ko03110				Bacteria	1HXIP@117743,2PAG8@246874,4NE1B@976,COG1219@1,COG1219@2	NA|NA|NA	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAG.T21.18_01700	1453500.AT05_05955	8.3e-53	214.2	Flavobacteriia													Bacteria	1IJIE@117743,4P246@976,COG0457@1,COG0457@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.18_01701	1122176.KB903598_gene4646	2.5e-14	87.4	Bacteria													Bacteria	COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_01702	1122176.KB903598_gene4646	2.6e-24	120.6	Bacteria													Bacteria	COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_01703	411154.GFO_1817	1.3e-150	540.0	Flavobacteriia	yidK												Bacteria	1HYVB@117743,4NEN8@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.18_01705	1313421.JHBV01000029_gene2009	1.8e-37	163.7	Bacteroidetes													Bacteria	4NKCW@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_01706	929556.Solca_2890	1.4e-139	503.1	Sphingobacteriia													Bacteria	1IQJT@117747,4NDUF@976,COG0534@1,COG0534@2	NA|NA|NA	V	Mate efflux family protein
MAG.T21.18_01707	479434.Sthe_2194	3.1e-14	85.9	Bacteria													Bacteria	COG1225@1,COG1225@2	NA|NA|NA	O	peroxiredoxin activity
MAG.T21.18_01709	755732.Fluta_0535	3.1e-141	509.2	Cryomorphaceae	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1I7MT@117743,2PAFS@246874,4NE88@976,COG1555@1,COG1555@2	NA|NA|NA	L	Psort location OuterMembrane, score
MAG.T21.18_01710	1313421.JHBV01000043_gene2974	3.9e-36	158.7	Sphingobacteriia	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1J0F4@117747,4NUGB@976,COG1555@1,COG1555@2	NA|NA|NA	L	photosystem II stabilization
MAG.T21.18_01711	1356852.N008_03865	8.2e-51	206.8	Cytophagia	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,2.7.4.3,6.3.4.19	ko:K00760,ko:K00939,ko:K15780	ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130	M00049	R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319	RC00002,RC00063,RC00122	ko00000,ko00001,ko00002,ko01000,ko03016,ko04147			iHN637.CLJU_RS16720	Bacteria	47PQ9@768503,4NNIB@976,COG0634@1,COG0634@2	NA|NA|NA	F	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAG.T21.18_01712	1046627.BZARG_903	1.9e-58	232.3	Flavobacteriia	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,2.7.4.3,6.3.4.19	ko:K00760,ko:K00939,ko:K15780	ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130	M00049	R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319	RC00002,RC00063,RC00122	ko00000,ko00001,ko00002,ko01000,ko03016,ko04147			iHN637.CLJU_RS16720	Bacteria	1HWR5@117743,4NG7J@976,COG0563@1,COG0563@2,COG0634@1,COG0634@2	NA|NA|NA	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAG.T21.18_01713	1453500.AT05_10710	1.6e-132	479.2	Flavobacteriia	obg	GO:0000003,GO:0000160,GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007059,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0019954,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0034622,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042254,GO:0042255,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1990904		ko:K03979					ko00000,ko01000,ko03009				Bacteria	1HXN1@117743,4NEK4@976,COG0536@1,COG0536@2	NA|NA|NA	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAG.T21.18_01714	886379.AEWI01000024_gene367	4.8e-36	157.9	Marinilabiliaceae	ybjG		3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	2FRKS@200643,3XK0T@558415,4NNVQ@976,COG0671@1,COG0671@2	NA|NA|NA	I	Acid phosphatase homologues
MAG.T21.18_01715	926562.Oweho_3551	1.6e-21	109.0	Cryomorphaceae	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425		ko:K06199					ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3			Bacteria	1IEE9@117743,2PBA2@246874,4P9SD@976,COG0239@1,COG0239@2	NA|NA|NA	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAG.T21.18_01716	313596.RB2501_09690	4.5e-132	478.4	Flavobacteriia	phoK		3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	1HXJR@117743,4NE94@976,COG1524@1,COG1524@2	NA|NA|NA	P	type I phosphodiesterase nucleotide pyrophosphatase
MAG.T21.18_01717	755732.Fluta_1925	1.7e-117	429.1	Cryomorphaceae	deoC		4.1.2.4	ko:K01619	ko00030,map00030		R01066	RC00436,RC00437	ko00000,ko00001,ko01000				Bacteria	1ICQK@117743,2PBS2@246874,4NGE3@976,COG0274@1,COG0274@2	NA|NA|NA	F	DeoC/LacD family aldolase
MAG.T21.18_01718	1123277.KB893174_gene5927	2.8e-87	330.5	Cytophagia													Bacteria	47XEG@768503,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_01719	1227739.Hsw_PA0072	4e-56	224.9	Cytophagia				ko:K02477					ko00000,ko02022				Bacteria	47PTI@768503,4NFPV@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator of the LytR AlgR family
MAG.T21.18_01721	1353529.M899_2569	1.1e-22	115.2	Proteobacteria				ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	1N928@1224,COG0729@1,COG0729@2,COG2911@1,COG2911@2	NA|NA|NA	M	Chaperone of endosialidase
MAG.T21.18_01722	1227739.Hsw_4210	5e-53	215.7	Bacteria													Bacteria	COG3391@1,COG3391@2	NA|NA|NA	CO	amine dehydrogenase activity
MAG.T21.18_01724	1454004.AW11_00930	3.7e-41	175.3	unclassified Betaproteobacteria													Bacteria	1KR2C@119066,1R8VC@1224,2C3WA@1,2WC2P@28216,2Z8P1@2	NA|NA|NA		
MAG.T21.18_01725	487796.Flav2ADRAFT_0265	3.5e-15	87.0	Flavobacteriia				ko:K09165					ko00000				Bacteria	1I534@117743,4NURJ@976,COG3360@1,COG3360@2	NA|NA|NA	S	Dodecin
MAG.T21.18_01726	1122179.KB890416_gene2721	2.8e-51	211.1	Sphingobacteriia													Bacteria	1J1A0@117747,4PM4C@976,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
MAG.T21.18_01727	1288963.ADIS_4677	3.3e-46	191.0	Cytophagia													Bacteria	47RKH@768503,4NWSG@976,COG2764@1,COG2764@2	NA|NA|NA	S	glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.18_01728	1487953.JMKF01000095_gene5154	5.1e-11	74.7	Bacteria													Bacteria	COG5485@1,COG5485@2	NA|NA|NA	S	SnoaL-like polyketide cyclase
MAG.T21.18_01732	886379.AEWI01000023_gene66	6.8e-20	105.1	Marinilabiliaceae													Bacteria	2E8XD@1,2FVQT@200643,3337D@2,3XKVX@558415,4NW3N@976	NA|NA|NA		
MAG.T21.18_01733	1484460.JSWG01000004_gene2569	9.1e-13	81.3	Flavobacteriia			3.4.21.96	ko:K01361,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	1I3TQ@117743,4NRWQ@976,COG1404@1,COG1404@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_01734	504487.JCM19302_142	4.3e-19	102.4	Flavobacteriia													Bacteria	1IB6C@117743,2A802@1,30X09@2,4PACI@976	NA|NA|NA		
MAG.T21.18_01735	1313421.JHBV01000028_gene1857	3.4e-193	683.7	Bacteroidetes				ko:K12287					ko00000,ko02044				Bacteria	4NJ47@976,COG1357@1,COG1357@2,COG1404@1,COG1404@2,COG3291@1,COG3291@2	NA|NA|NA	U	PFAM PKD domain
MAG.T21.18_01736	886379.AEWI01000023_gene67	1.3e-06	60.5	Bacteroidetes				ko:K03933,ko:K12287					ko00000,ko02044		AA10,CBM73		Bacteria	4NKK9@976,COG3291@1,COG3291@2,COG5306@1,COG5306@2	NA|NA|NA	S	aminopeptidase activity
MAG.T21.18_01737	1168034.FH5T_07230	5.7e-16	92.0	Bacteroidia													Bacteria	2E8XD@1,2FVQT@200643,3337D@2,4NW3N@976	NA|NA|NA		
MAG.T21.18_01738	1166018.FAES_3457	2.3e-47	195.7	Cytophagia													Bacteria	47PWE@768503,4NHTM@976,COG2197@1,COG2197@2	NA|NA|NA	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.18_01739	485918.Cpin_4159	2.4e-67	264.2	Sphingobacteriia													Bacteria	1IW62@117747,4PI9B@976,COG3292@1,COG3292@2,COG4585@1,COG4585@2	NA|NA|NA	T	Two component regulator three Y
MAG.T21.18_01740	746697.Aeqsu_1273	2.1e-23	115.9	Flavobacteriia				ko:K03088,ko:K03091					ko00000,ko03021				Bacteria	1IJ13@117743,4NRAJ@976,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70 region 2
MAG.T21.18_01741	1189612.A33Q_2651	2.8e-22	112.5	Bacteroidetes													Bacteria	4NNXW@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_01742	1223410.KN050846_gene2260	1.6e-85	324.7	Flavobacteriia													Bacteria	1HXNK@117743,4NHCZ@976,COG0457@1,COG0457@2,COG4995@1,COG4995@2	NA|NA|NA	S	CHAT domain
MAG.T21.18_01743	1121373.KB903663_gene1207	1.4e-85	323.2	Cytophagia													Bacteria	47RPD@768503,4NMHK@976,COG5285@1,COG5285@2	NA|NA|NA	Q	Phytanoyl-CoA dioxygenase (PhyH)
MAG.T21.18_01744	926562.Oweho_2644	8.9e-55	220.3	Cryomorphaceae	ypmQ			ko:K07152,ko:K08976					ko00000,ko03029				Bacteria	1HXP2@117743,2PAWG@246874,4NFH2@976,COG1999@1,COG1999@2	NA|NA|NA	S	SCO1/SenC
MAG.T21.18_01745	1121101.HMPREF1532_02648	2.5e-07	62.8	Bacteroidaceae													Bacteria	2E6TM@1,2FPEV@200643,331DG@2,4APRK@815,4NYW8@976	NA|NA|NA	S	Protein of unknown function (DUF2490)
MAG.T21.18_01746	1121899.Q764_05285	2.6e-13	81.6	Flavobacterium													Bacteria	1ICZ6@117743,2A9DB@1,2NWA7@237,30YIH@2,4PCCI@976	NA|NA|NA		
MAG.T21.18_01747	906888.JCM19314_3740	4.5e-183	647.9	Nonlabens	fadD		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	1HXQU@117743,3HJ8X@363408,4NEA4@976,COG1022@1,COG1022@2	NA|NA|NA	I	AMP-dependent synthetase
MAG.T21.18_01749	929703.KE386491_gene3827	4.6e-19	100.9	Cytophagia													Bacteria	29WC5@1,30HXS@2,47SJP@768503,4NNWN@976	NA|NA|NA		
MAG.T21.18_01750	1515615.HQ41_06750	1.2e-95	356.7	Porphyromonadaceae	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944											Bacteria	22Z0Q@171551,2FQPC@200643,4NH8V@976,COG0330@1,COG0330@2	NA|NA|NA	O	SPFH Band 7 PHB domain protein
MAG.T21.18_01751	335543.Sfum_2309	4.1e-19	101.3	Bacteria	nfeD			ko:K07340					ko00000				Bacteria	COG1585@1,COG1585@2	NA|NA|NA	OU	cellular response to DNA damage stimulus
MAG.T21.18_01752	1379698.RBG1_1C00001G1736	1.2e-40	174.9	Bacteria													Bacteria	COG2244@1,COG2244@2	NA|NA|NA	S	polysaccharide biosynthetic process
MAG.T21.18_01753	864051.BurJ1DRAFT_4143	1.8e-78	299.7	Betaproteobacteria	bplH												Bacteria	1MU9C@1224,2WERP@28216,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferase 4-like
MAG.T21.18_01754	1408433.JHXV01000024_gene1492	4.9e-68	265.0	Cryomorphaceae	exoA												Bacteria	1ICDJ@117743,2PB9X@246874,4NT9I@976,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_01755	755732.Fluta_2179	5e-22	112.5	Cryomorphaceae				ko:K02847	ko00540,ko01100,map00540,map01100	M00080			ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5			Bacteria	1ICS9@117743,2PBZ8@246874,4NXNX@976,COG3307@1,COG3307@2	NA|NA|NA	M	O-Antigen ligase
MAG.T21.18_01756	755732.Fluta_2193	1e-128	466.8	Cryomorphaceae	spsC		2.6.1.102	ko:K13010	ko00520,map00520		R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007				Bacteria	1HZBY@117743,2PBDW@246874,4NFQ8@976,COG0399@1,COG0399@2	NA|NA|NA	E	DegT/DnrJ/EryC1/StrS aminotransferase family
MAG.T21.18_01757	616991.JPOO01000001_gene4218	1.6e-55	222.6	Arenibacter	bplG												Bacteria	1I2JE@117743,23HXR@178469,4NNHR@976,COG2148@1,COG2148@2	NA|NA|NA	M	Bacterial sugar transferase
MAG.T21.18_01758	1408433.JHXV01000023_gene3302	2.8e-73	283.1	Cryomorphaceae				ko:K03933					ko00000		AA10,CBM73		Bacteria	1ICPP@117743,2PBJ2@246874,4PBW3@976,COG3291@1,COG3291@2	NA|NA|NA	S	PA domain
MAG.T21.18_01759	391596.PBAL39_09731	6e-75	287.7	Sphingobacteriia													Bacteria	1IP0V@117747,4NF8R@976,COG2912@1,COG2912@2	NA|NA|NA	S	Transglutaminase-like superfamily
MAG.T21.18_01760	1183438.GKIL_4231	5.9e-62	245.0	Cyanobacteria													Bacteria	1G1SZ@1117,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferase, group 1 family protein
MAG.T21.18_01761	338966.Ppro_1421	4.1e-34	152.5	Deltaproteobacteria													Bacteria	1PFC7@1224,2WWVJ@28221,439Z9@68525,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01762	398767.Glov_2747	5.3e-49	201.4	delta/epsilon subdivisions				ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	1RDAK@1224,42U4I@68525,COG0438@1,COG0438@2,COG1216@1,COG1216@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.18_01763	56780.SYN_02664	1.1e-60	240.4	Deltaproteobacteria													Bacteria	1RD8N@1224,2WPYH@28221,2ZC3Y@2,42SZD@68525,arCOG09486@1	NA|NA|NA	S	N-acetyllactosaminide 3-alpha-galactosyltransferase activity
MAG.T21.18_01764	765910.MARPU_05290	5.4e-34	151.8	Chromatiales													Bacteria	1MZSD@1224,1S9D2@1236,1WZ3T@135613,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
MAG.T21.18_01765	1496688.ER33_11365	1.3e-46	193.7	Cyanobium	lgtA			ko:K00786					ko00000,ko01000				Bacteria	1GHSH@1117,22T8Q@167375,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.18_01766	1232410.KI421416_gene2569	1.6e-96	359.8	Desulfuromonadales													Bacteria	1PFZM@1224,2X9QU@28221,42Z5H@68525,43VPG@69541,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01767	315749.Bcer98_1373	1.3e-46	193.4	Bacillus			2.1.1.294,2.7.1.181	ko:K18827			R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005				Bacteria	1UZT6@1239,1ZEN6@1386,4HFIA@91061,COG0438@1,COG0438@2,COG2227@1,COG2227@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_01768	243231.GSU1505	1.4e-95	356.7	Desulfuromonadales			3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103			Bacteria	1MWWC@1224,2WMWA@28221,42NNW@68525,43T6N@69541,COG1134@1,COG1134@2	NA|NA|NA	GM	ABC transporter
MAG.T21.18_01769	272134.KB731324_gene4476	1.5e-83	316.2	Oscillatoriales				ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103			Bacteria	1G23R@1117,1H8WK@1150,COG1682@1,COG1682@2	NA|NA|NA	GM	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component
MAG.T21.18_01771	1408473.JHXO01000005_gene1442	1.1e-145	523.5	Bacteroidia	rumA		2.1.1.190	ko:K03215					ko00000,ko01000,ko03009				Bacteria	2FNRC@200643,4NFP1@976,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAG.T21.18_01772	1189612.A33Q_0785	9.1e-59	233.8	Cytophagia	tpm		2.1.1.67	ko:K00569	ko00983,map00983		R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000				Bacteria	47Q1Z@768503,4NNNE@976,COG0500@1,COG0500@2	NA|NA|NA	Q	Thiopurine S-methyltransferase (TPMT)
MAG.T21.18_01773	1214101.BN159_6008	6.9e-10	70.5	Actinobacteria													Bacteria	2IMR2@201174,COG5646@1,COG5646@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_01774	616991.JPOO01000003_gene1126	2.5e-30	138.7	Arenibacter	pyrR	GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000,ko03000				Bacteria	1I2CB@117743,23GSB@178469,4NNRI@976,COG2065@1,COG2065@2	NA|NA|NA	F	Phosphoribosyl transferase domain
MAG.T21.18_01775	483216.BACEGG_03435	1.7e-24	119.4	Bacteroidaceae	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71,4.2.3.4	ko:K00891,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000				Bacteria	2FM3K@200643,4ANJB@815,4NQ73@976,COG0703@1,COG0703@2	NA|NA|NA	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MAG.T21.18_01776	926549.KI421517_gene3524	1.3e-104	386.7	Cytophagia													Bacteria	47M7W@768503,4NFWE@976,COG0454@1,COG0456@2	NA|NA|NA	K	Psort location Cytoplasmic, score 8.96
MAG.T21.18_01779	1239415.CM001837_gene2901	1.2e-07	62.0	Dokdonia													Bacteria	1IFTD@117743,2AB6S@1,310M3@2,37FTJ@326319,4PF7G@976	NA|NA|NA		
MAG.T21.18_01780	1121898.Q766_20100	1.3e-14	88.2	Flavobacterium													Bacteria	1HZNR@117743,2C5U1@1,2NSK5@237,2Z80K@2,4NG4G@976	NA|NA|NA		
MAG.T21.18_01781	984262.SGRA_0593	1.2e-85	323.6	Sphingobacteriia													Bacteria	1IQ7F@117747,4NEA8@976,COG1804@1,COG1804@2	NA|NA|NA	C	PFAM CoA-transferase family III
MAG.T21.18_01782	1408433.JHXV01000030_gene1398	4.5e-48	200.7	Cryomorphaceae													Bacteria	1ICNQ@117743,2PBCJ@246874,4P3PK@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeats
MAG.T21.18_01783	1356852.N008_07750	3.1e-76	292.4	Cytophagia	puuB			ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000				Bacteria	47JUY@768503,4NEEY@976,COG0665@1,COG0665@2	NA|NA|NA	E	Glycine D-amino acid oxidase (deaminating)
MAG.T21.18_01784	1305737.JAFX01000001_gene1081	3.2e-183	648.3	Cytophagia	yjgR			ko:K06915					ko00000				Bacteria	47M2I@768503,4NF3P@976,COG0433@1,COG0433@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF853)
MAG.T21.18_01788	491205.JARQ01000009_gene3318	8.6e-54	217.6	Chryseobacterium													Bacteria	1I8D0@117743,3ZPBH@59732,4NU2D@976,COG1215@1,COG1215@2	NA|NA|NA	M	Capsular biosynthesis protein CpsI
MAG.T21.18_01789	1121459.AQXE01000004_gene1766	4.3e-65	255.4	Desulfovibrionales				ko:K16703					ko00000,ko01000,ko01003		GT4		Bacteria	1PGDM@1224,2MCV1@213115,2X9FF@28221,4363T@68525,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferase 4-like domain
MAG.T21.18_01790	768671.ThimaDRAFT_3484	3.2e-53	215.7	Gammaproteobacteria				ko:K06219					ko00000				Bacteria	1QXQ4@1224,1T3G0@1236,COG1442@1,COG1442@2,COG2227@1,COG2227@2	NA|NA|NA	H	Methyltransferase domain
MAG.T21.18_01791	768671.ThimaDRAFT_3485	1.5e-39	170.2	Gammaproteobacteria													Bacteria	1P4F1@1224,1SV4B@1236,COG1442@1,COG1442@2	NA|NA|NA	M	glycosyl transferase family 8
MAG.T21.18_01792	1249480.B649_08590	9.8e-68	263.5	Epsilonproteobacteria	yjnA			ko:K07090					ko00000				Bacteria	1R3V4@1224,2YNYS@29547,42NFH@68525,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.18_01793	865937.Gilli_0672	1.6e-46	193.4	Gillisia		GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016740,GO:0016757,GO:0030312,GO:0044464,GO:0071944											Bacteria	1I2VG@117743,2P71U@244698,4NQNJ@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.18_01795	700598.Niako_5353	3.9e-54	218.4	Sphingobacteriia													Bacteria	1IXTP@117747,4NI1S@976,COG4122@1,COG4122@2	NA|NA|NA	S	WbqC-like protein family
MAG.T21.18_01796	211586.SO_3183	3.2e-58	232.3	Gammaproteobacteria													Bacteria	1REP8@1224,1S7G9@1236,COG0399@1,COG0399@2	NA|NA|NA	M	Belongs to the DegT DnrJ EryC1 family
MAG.T21.18_01797	880073.Calab_2795	3e-52	212.2	Bacteria													Bacteria	2BDYA@1,327NJ@2	NA|NA|NA	S	Sulfotransferase domain
MAG.T21.18_01798	1121481.AUAS01000001_gene4491	9.3e-102	377.1	Cytophagia	vioA	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308,ko:K20429	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000				Bacteria	47KCG@768503,4NGI4@976,COG0399@1,COG0399@2	NA|NA|NA	E	Belongs to the DegT DnrJ EryC1 family
MAG.T21.18_01799	1121406.JAEX01000016_gene1873	8.3e-22	111.3	Bacteria			3.5.1.104	ko:K22278					ko00000,ko01000				Bacteria	COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
MAG.T21.18_01800	118163.Ple7327_2119	4.1e-82	312.0	Pleurocapsales			3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103			Bacteria	1FZUV@1117,3VINY@52604,COG1134@1,COG1134@2	NA|NA|NA	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component
MAG.T21.18_01801	765911.Thivi_0121	8e-77	293.9	Chromatiales	kpsM			ko:K09690	ko02010,map02010	M00250			ko00000,ko00001,ko00002,ko02000	3.A.1.103			Bacteria	1N1G2@1224,1SZFG@1236,1X2K1@135613,COG1682@1,COG1682@2	NA|NA|NA	GM	PFAM ABC-2 type transporter
MAG.T21.18_01802	1408433.JHXV01000029_gene3104	8.6e-148	531.2	Cryomorphaceae	wzc	GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576		ko:K16692					ko00000,ko01000,ko01001				Bacteria	1HXKJ@117743,2PA6D@246874,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2	NA|NA|NA	DM	Chain length determinant protein
MAG.T21.18_01803	1408433.JHXV01000029_gene3101	3.8e-27	128.3	Cryomorphaceae													Bacteria	1IM56@117743,2PC15@246874,4P9XV@976,COG4083@1,COG4083@2	NA|NA|NA	S	Transmembrane exosortase (Exosortase_EpsH)
MAG.T21.18_01805	1279009.ADICEAN_00490	1.4e-181	642.5	Cytophagia	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000			iG2583_1286.G2583_3081,iIT341.HP0183	Bacteria	47JWG@768503,4NE30@976,COG0112@1,COG0112@2	NA|NA|NA	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAG.T21.18_01806	143224.JQMD01000002_gene1424	7.3e-155	553.9	Flavobacteriia													Bacteria	1HWM1@117743,4NFK5@976,COG1696@1,COG1696@2	NA|NA|NA	M	Membrane protein involved in D-alanine export
MAG.T21.18_01807	497964.CfE428DRAFT_4096	1.6e-07	63.9	Bacteria													Bacteria	2D25X@1,32TC5@2	NA|NA|NA		
MAG.T21.18_01808	929704.Myrod_2901	4.4e-13	82.0	Flavobacteriia													Bacteria	1IIAF@117743,4NQY0@976,COG3011@1,COG3011@2	NA|NA|NA	S	Vitamin K-dependent gamma-carboxylase
MAG.T21.18_01810	143224.JQMD01000002_gene592	1.9e-146	525.8	Flavobacteriia	fahA		3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1HXN9@117743,4NGI0@976,COG0179@1,COG0179@2	NA|NA|NA	Q	Fumarylacetoacetase
MAG.T21.18_01811	762903.Pedsa_2021	5.3e-253	880.6	Sphingobacteriia	relA		2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230		R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009				Bacteria	1IQ2F@117747,4NESY@976,COG0317@1,COG0317@2	NA|NA|NA	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAG.T21.18_01813	867902.Ornrh_1560	4e-25	120.9	Flavobacteriia	hslR	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.23,5.4.99.24	ko:K04762,ko:K06179,ko:K06180					ko00000,ko01000,ko03009,ko03110				Bacteria	1I22D@117743,4NP8I@976,COG1188@1,COG1188@2	NA|NA|NA	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MAG.T21.18_01814	760192.Halhy_6539	2.2e-29	137.1	Bacteroidetes	rseP			ko:K11749	ko02024,ko04112,map02024,map04112				ko00000,ko00001,ko01000,ko01002				Bacteria	4PP2A@976,COG0265@1,COG0265@2,COG0750@1,COG0750@2	NA|NA|NA	O	zinc metalloprotease
MAG.T21.18_01815	1237149.C900_05112	1.9e-17	95.5	Cytophagia	yvlD			ko:K08972					ko00000				Bacteria	47S20@768503,4NT2I@976,COG1950@1,COG1950@2	NA|NA|NA	S	PFAM Membrane protein of
MAG.T21.18_01816	1341181.FLJC2902T_02810	2.3e-102	378.6	Flavobacterium													Bacteria	1HWN1@117743,2NSWY@237,4NFNA@976,COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
MAG.T21.18_01817	1122176.KB903539_gene1381	7.4e-281	973.0	Sphingobacteriia	bfmBAB		1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IV4C@117747,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2	NA|NA|NA	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type
MAG.T21.18_01818	1356852.N008_19240	5.2e-44	184.5	Cytophagia													Bacteria	47QUH@768503,4NHWT@976,COG0400@1,COG0400@2	NA|NA|NA	S	PFAM phospholipase Carboxylesterase
MAG.T21.18_01819	1279009.ADICEAN_00512	1.4e-201	709.5	Cytophagia	pepN												Bacteria	47M3W@768503,4NFT0@976,COG0308@1,COG0308@2	NA|NA|NA	E	Leukotriene A4 hydrolase, C-terminal
MAG.T21.18_01821	1121288.AULL01000010_gene1413	3.2e-21	107.5	Chryseobacterium	yazA			ko:K07461					ko00000				Bacteria	1I58Q@117743,3ZSSH@59732,4NVHC@976,COG2827@1,COG2827@2	NA|NA|NA	L	GIY-YIG catalytic domain
MAG.T21.18_01825	991.IW20_20425	1.2e-96	360.1	Flavobacterium													Bacteria	1HYYV@117743,2CB8G@1,2NSPI@237,2Z88H@2,4NF68@976	NA|NA|NA	S	Putative beta-barrel porin-2, OmpL-like. bbp2
MAG.T21.18_01826	926562.Oweho_2290	1.4e-40	174.1	Cryomorphaceae			3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100		R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000				Bacteria	1IEIA@117743,2PBEA@246874,4NM0Q@976,COG3049@1,COG3049@2	NA|NA|NA	M	Linear amide C-N hydrolases, choloylglycine hydrolase family
MAG.T21.18_01827	1124780.ANNU01000038_gene203	1.6e-15	89.7	Bacteroidetes													Bacteria	2EMGK@1,33F59@2,4NYBS@976	NA|NA|NA		
MAG.T21.18_01828	307480.IW16_13535	6.8e-60	237.3	Chryseobacterium													Bacteria	1I0KM@117743,3ZR7D@59732,4NGMR@976,COG0702@1,COG0702@2	NA|NA|NA	GM	NAD dependent epimerase/dehydratase family
MAG.T21.18_01829	1122179.KB890440_gene1026	2.3e-117	428.7	Sphingobacteriia	yneE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K08994					ko00000,ko02000	1.A.46.2			Bacteria	1IVFH@117747,4NGJ0@976,COG3781@1,COG3781@2	NA|NA|NA	S	Bestrophin, RFP-TM, chloride channel
MAG.T21.18_01830	1227739.Hsw_1210	6.5e-87	327.0	Cytophagia	yadF		4.2.1.1	ko:K01673	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000			iNJ661.Rv3273	Bacteria	47MBG@768503,4NEJT@976,COG0288@1,COG0288@2	NA|NA|NA	P	Reversible hydration of carbon dioxide
MAG.T21.18_01831	411154.GFO_1584	1.3e-100	373.2	Flavobacteriia													Bacteria	1HWY9@117743,4NENZ@976,COG2220@1,COG2220@2	NA|NA|NA	S	beta-lactamase
MAG.T21.18_01833	1469557.JSWF01000036_gene808	1.8e-20	107.8	Bacteria	htaA		3.4.21.72	ko:K01347,ko:K03561,ko:K12287					ko00000,ko01000,ko01002,ko02000,ko02044	1.A.30.2.1,1.B.12.3			Bacteria	COG3209@1,COG3209@2,COG3291@1,COG3291@2,COG3897@1,COG3897@2,COG4886@1,COG4886@2,COG5306@1,COG5306@2,COG5492@1,COG5492@2	NA|NA|NA	P	peptidase activity, acting on L-amino acid peptides
MAG.T21.18_01835	269798.CHU_1303	5.2e-37	161.4	Bacteroidetes			1.11.1.15,2.7.13.3	ko:K03564,ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	4NXEC@976,COG1225@1,COG1225@2	NA|NA|NA	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.18_01836	1463887.KL590002_gene4233	8.2e-37	160.2	Actinobacteria													Bacteria	2AQME@1,2GJ2E@201174,31FUG@2	NA|NA|NA		
MAG.T21.18_01837	700598.Niako_5661	2.4e-63	250.0	Sphingobacteriia													Bacteria	1IPPV@117747,2DBC9@1,2Z8CA@2,4NJS4@976	NA|NA|NA	S	Domain of unknown function (DUF4173)
MAG.T21.18_01838	153721.MYP_166	2.8e-26	124.4	Cytophagia													Bacteria	47XWV@768503,4PKEM@976,COG1695@1,COG1695@2	NA|NA|NA	K	Winged helix DNA-binding domain
MAG.T21.18_01839	1279009.ADICEAN_03425	5e-43	181.4	Cytophagia				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	47P7G@768503,4NN8S@976,COG3127@1,COG3127@2	NA|NA|NA	Q	membrane
MAG.T21.18_01840	755732.Fluta_2261	1.8e-40	172.9	Cryomorphaceae	zupT			ko:K07238,ko:K11021,ko:K16267					ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5			Bacteria	1HYRJ@117743,2PB10@246874,4NG1R@976,COG0428@1,COG0428@2	NA|NA|NA	P	ZIP Zinc transporter
MAG.T21.18_01841	1227739.Hsw_0027	2e-39	169.5	Cytophagia													Bacteria	47XZB@768503,4PKUR@976,COG2227@1,COG2227@2	NA|NA|NA	H	Tellurite resistance protein TehB
MAG.T21.18_01842	755732.Fluta_2263	3.6e-33	148.3	Cryomorphaceae													Bacteria	1ICQH@117743,2AAU0@1,2PBRJ@246874,3106Q@2,4NNSV@976	NA|NA|NA		
MAG.T21.18_01843	927658.AJUM01000047_gene2816	3.9e-42	177.6	Marinilabiliaceae													Bacteria	2AD7J@1,2G24U@200643,312WH@2,3XK3Q@558415,4NR1A@976	NA|NA|NA	S	Domain of unknown function (DUF1987)
MAG.T21.18_01844	1408433.JHXV01000017_gene1629	3.4e-287	994.6	Cryomorphaceae		GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944		ko:K01990,ko:K21397		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1I942@117743,2PBH5@246874,4NHPD@976,COG0842@1,COG0842@2,COG1131@1,COG1131@2	NA|NA|NA	V	ABC-2 type transporter
MAG.T21.18_01845	1408433.JHXV01000017_gene1628	1e-24	119.8	Cryomorphaceae													Bacteria	1ICSI@117743,290ZX@1,2PC01@246874,2ZNMM@2,4P891@976	NA|NA|NA		
MAG.T21.18_01846	1408433.JHXV01000017_gene1627	9.6e-36	157.5	Cryomorphaceae													Bacteria	1ICPZ@117743,29N3N@1,2PBKH@246874,32D2M@2,4NRTM@976	NA|NA|NA		
MAG.T21.18_01847	925409.KI911562_gene606	5.8e-98	364.8	Sphingobacteriia	gluP												Bacteria	1IQFZ@117747,4NEYR@976,COG0738@1,COG0738@2	NA|NA|NA	G	PFAM Major Facilitator Superfamily
MAG.T21.18_01849	667015.Bacsa_2185	3.1e-206	725.3	Bacteroidaceae	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K04066	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2FN6Z@200643,4AM5E@815,4NFHB@976,COG1198@1,COG1198@2	NA|NA|NA	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAG.T21.18_01850	760192.Halhy_2127	2.6e-38	165.6	Sphingobacteriia			5.4.99.23	ko:K06180					ko00000,ko01000,ko03009				Bacteria	1IR96@117747,4NFS8@976,COG0564@1,COG0564@2	NA|NA|NA	J	PFAM Pseudouridine synthase, RsuA and RluB C D E F
MAG.T21.18_01851	926562.Oweho_1165	2.8e-111	408.3	Cryomorphaceae	panB		2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXEE@117743,2PAFE@246874,4NDX4@976,COG0413@1,COG0413@2	NA|NA|NA	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MAG.T21.18_01852	1408433.JHXV01000005_gene2262	5.8e-25	122.1	Cryomorphaceae													Bacteria	1I9V5@117743,2CA1R@1,2PBA8@246874,32FVT@2,4PBTZ@976	NA|NA|NA		
MAG.T21.18_01853	929556.Solca_2982	2.2e-284	984.6	Sphingobacteriia	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141		ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1			Bacteria	1IPCI@117747,4NERF@976,COG0443@1,COG0443@2	NA|NA|NA	O	Heat shock 70 kDa protein
MAG.T21.18_01855	1124780.ANNU01000056_gene3481	2.6e-144	518.8	Cytophagia	nhaC			ko:K03315					ko00000,ko02000	2.A.35			Bacteria	47KKY@768503,4NFQT@976,COG1757@1,COG1757@2	NA|NA|NA	C	TIGRFAM Na H antiporter NhaC
MAG.T21.18_01856	1121889.AUDM01000014_gene1970	3e-56	228.8	Flavobacterium		GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944											Bacteria	1IMXD@117743,2NV4Y@237,4NJHV@976,COG3227@1,COG3227@2,COG3291@1,COG3291@2,COG3391@1,COG3391@2	NA|NA|NA	O	Fibronectin type 3 domain
MAG.T21.18_01857	1123059.KB823013_gene496	8.4e-125	453.8	Alphaproteobacteria													Bacteria	1MX3S@1224,2U1KM@28211,COG3876@1,COG3876@2	NA|NA|NA	S	Protein of unknown function (DUF1343)
MAG.T21.18_01858	1408433.JHXV01000026_gene3024	1.2e-68	267.7	Cryomorphaceae	lolE_1			ko:K09808	ko02010,map02010	M00255			ko00000,ko00001,ko00002,ko02000	3.A.1.125			Bacteria	1HWT5@117743,2PATT@246874,4NFWZ@976,COG4591@1,COG4591@2	NA|NA|NA	M	ABC-type transport system involved in lipoprotein release permease component
MAG.T21.18_01859	929556.Solca_1154	8.6e-182	643.3	Sphingobacteriia	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQU6@117747,4NDZ9@976,COG0031@1,COG0031@2,COG3620@1,COG3620@2	NA|NA|NA	E	Cystathionine beta-synthase
MAG.T21.18_01861	1313421.JHBV01000029_gene1942	5.8e-77	294.3	Sphingobacteriia	fecB			ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1IPYQ@117747,4NI2Y@976,COG0614@1,COG0614@2	NA|NA|NA	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component
MAG.T21.18_01862	755732.Fluta_2733	3.7e-153	548.9	Cryomorphaceae	plpD			ko:K07001					ko00000				Bacteria	1HWZP@117743,2PBJS@246874,4NDXY@976,COG1752@1,COG1752@2	NA|NA|NA	M	Patatin-like phospholipase
MAG.T21.18_01863	1408813.AYMG01000010_gene623	5.8e-36	156.8	Sphingobacteriia			2.7.11.1,4.6.1.1	ko:K01768,ko:K12132	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001				Bacteria	1ISVX@117747,4NSNP@976,COG4191@1,COG4191@2	NA|NA|NA	T	Protein of unknown function (DUF3467)
MAG.T21.18_01864	926562.Oweho_1469	4.6e-231	807.4	Cryomorphaceae	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1HYVS@117743,2PACC@246874,4NEMW@976,COG0086@1,COG0086@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAG.T21.18_01865	485918.Cpin_1400	1.1e-13	82.8	Sphingobacteriia													Bacteria	1IPPI@117747,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2	NA|NA|NA	T	PFAM Signal transduction histidine kinase, internal region
MAG.T21.18_01866	471854.Dfer_5645	1.3e-46	193.4	Cytophagia				ko:K02477					ko00000,ko02022				Bacteria	47XDW@768503,4NK6R@976,COG3279@1,COG3279@2	NA|NA|NA	T	Two component transcriptional regulator, LytTR family
MAG.T21.18_01870	1406840.Q763_09260	5e-70	273.5	Flavobacterium													Bacteria	1HX5A@117743,2NU73@237,4NDZQ@976,COG3291@1,COG3291@2	NA|NA|NA	O	C-terminal domain of CHU protein family
MAG.T21.18_01871	1121889.AUDM01000033_gene1311	2.2e-48	199.9	Flavobacterium				ko:K15727					ko00000,ko02000	8.A.1.2.1			Bacteria	1HXZJ@117743,2NSC3@237,4NDW5@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.18_01872	1506583.JQJY01000005_gene2200	0.0	1275.0	Flavobacterium				ko:K15726					ko00000,ko02000	2.A.6.1.2			Bacteria	1IJ7V@117743,2NT81@237,4P36A@976,COG3696@1,COG3696@2	NA|NA|NA	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.18_01874	1115512.EH105704_01_01690	1.7e-28	132.1	Escherichia	yeaO												Bacteria	1MZ7H@1224,1S9PQ@1236,3XPSR@561,COG3189@1,COG3189@2	NA|NA|NA	S	Protein of unknown function, DUF488
MAG.T21.18_01875	1121889.AUDM01000017_gene2154	1.4e-101	375.9	Flavobacterium													Bacteria	1HZZK@117743,28IEW@1,2NUHR@237,2Z8GW@2,4NFZC@976	NA|NA|NA		
MAG.T21.18_01876	1122605.KB893643_gene529	3.3e-20	104.0	Sphingobacteriia				ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1ITFG@117747,4NSRJ@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin
MAG.T21.18_01877	1121957.ATVL01000008_gene4441	6.3e-30	137.5	Cytophagia													Bacteria	47QIA@768503,4NH0E@976,COG1846@1,COG1846@2	NA|NA|NA	K	MarR family
MAG.T21.18_01878	880071.Fleli_0964	4.1e-25	123.6	Cytophagia	rpfI		3.1.3.48	ko:K01104,ko:K21449,ko:K21473					ko00000,ko01000,ko01002,ko01011,ko02000	1.B.40.2			Bacteria	47TRC@768503,4NRRF@976,COG1196@1,COG1196@2,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_01879	880071.Fleli_0962	4.7e-59	235.3	Cytophagia													Bacteria	28UQ5@1,2ZGUJ@2,47TQT@768503,4NM5U@976	NA|NA|NA		
MAG.T21.18_01880	1123368.AUIS01000004_gene240	5.4e-12	78.2	Proteobacteria													Bacteria	1NMQ2@1224,2E6C6@1,330ZZ@2	NA|NA|NA		
MAG.T21.18_01881	1250232.JQNJ01000001_gene1416	1.1e-35	156.4	Flavobacteriia													Bacteria	1I9UU@117743,2DWGT@1,34096@2,4P4T6@976	NA|NA|NA	S	Domain of unknown function (DUF4440)
MAG.T21.18_01882	675812.VHA_002064	2.8e-118	431.8	Vibrionales	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147			iUTI89_1310.UTI89_C4836,ic_1306.c5329	Bacteria	1MW0E@1224,1RNFF@1236,1XT96@135623,COG0158@1,COG0158@2	NA|NA|NA	G	Belongs to the FBPase class 1 family
MAG.T21.18_01883	485917.Phep_2923	7.5e-39	166.8	Sphingobacteriia													Bacteria	1ISGA@117747,4PM4N@976,COG1247@1,COG1247@2	NA|NA|NA	M	Gnat family
MAG.T21.18_01884	1408433.JHXV01000040_gene1539	5.2e-104	384.8	Cryomorphaceae	lysC		2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWT8@117743,2PAIM@246874,4NF0M@976,COG0527@1,COG0527@2	NA|NA|NA	E	Amino acid kinase family
MAG.T21.18_01886	517418.Ctha_0575	5.2e-66	258.1	Chlorobi	glpQ		3.1.4.46	ko:K01126	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	1FDU3@1090,COG0584@1,COG0584@2	NA|NA|NA	C	PFAM glycerophosphoryl diester phosphodiesterase
MAG.T21.18_01887	755732.Fluta_1420	4.5e-68	265.0	Cryomorphaceae	serA		1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1HXGX@117743,2PAGW@246874,4NEMQ@976,COG0111@1,COG0111@2	NA|NA|NA	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MAG.T21.18_01888	991.IW20_14585	8e-98	364.4	Flavobacterium	mgtE			ko:K06213					ko00000,ko02000	1.A.26.1			Bacteria	1HX2X@117743,2NSJR@237,4NGGN@976,COG2239@1,COG2239@2	NA|NA|NA	P	Acts as a magnesium transporter
MAG.T21.18_01889	1279009.ADICEAN_02131	2e-71	275.8	Cytophagia	ksgA	GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.182	ko:K02528			R10716	RC00003,RC03257	ko00000,ko01000,ko03009				Bacteria	47KWT@768503,4NERB@976,COG0030@1,COG0030@2	NA|NA|NA	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MAG.T21.18_01890	1313301.AUGC01000001_gene1471	7e-23	113.2	Bacteroidetes													Bacteria	2C9BK@1,32RP1@2,4NSPA@976	NA|NA|NA	S	Domain of unknown function (DUF4286)
MAG.T21.18_01891	760192.Halhy_4030	8.4e-103	381.3	Sphingobacteriia				ko:K20543					ko00000,ko02000	1.B.55.3			Bacteria	1J0XE@117747,4PKMW@976,COG1729@1,COG1729@2,COG4783@1,COG4783@2	NA|NA|NA	G	Tetratricopeptide repeat
MAG.T21.18_01893	1121889.AUDM01000005_gene1743	4.8e-150	537.7	Flavobacterium	serS		6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1HY6A@117743,2NT7U@237,4NED6@976,COG0172@1,COG0172@2	NA|NA|NA	J	seryl-tRNA synthetase
MAG.T21.18_01894	1121957.ATVL01000011_gene3839	3e-30	137.5	Cytophagia	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904		ko:K02899	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	47R69@768503,4NS7T@976,COG0211@1,COG0211@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL27 family
MAG.T21.18_01895	1250232.JQNJ01000001_gene961	2.3e-31	142.1	Flavobacteriia	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02888	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1HYAI@117743,4NSHE@976,COG0261@1,COG0261@2	NA|NA|NA	J	This protein binds to 23S rRNA in the presence of protein L20
MAG.T21.18_01896	761193.Runsl_4707	1.2e-177	629.4	Cytophagia	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000				Bacteria	47JW7@768503,4NG7Y@976,COG0192@1,COG0192@2	NA|NA|NA	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAG.T21.18_01897	1453500.AT05_05120	3.1e-90	338.6	Flavobacteriia	gldA		3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115			Bacteria	1HWPM@117743,4NEH0@976,COG1131@1,COG1131@2	NA|NA|NA	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA
MAG.T21.18_01898	1034807.FBFL15_2632	5.3e-90	337.8	Flavobacterium	rsgA		3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100		R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009				Bacteria	1HX6Y@117743,2NSI6@237,4NE5H@976,COG1162@1,COG1162@2	NA|NA|NA	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAG.T21.18_01899	1237149.C900_05754	2e-48	199.5	Bacteroidetes	hel	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944											Bacteria	4NJIJ@976,COG2503@1,COG2503@2	NA|NA|NA	S	5'-nucleotidase, lipoprotein e(P4) family
MAG.T21.18_01900	1406840.Q763_10430	2.8e-44	184.9	Flavobacterium	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360		ko:K07560					ko00000,ko01000,ko03016				Bacteria	1I1XN@117743,2NW14@237,4NNFF@976,COG1490@1,COG1490@2	NA|NA|NA	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAG.T21.18_01901	1121889.AUDM01000008_gene766	8.8e-38	165.6	Flavobacterium													Bacteria	1HY1K@117743,2NSFX@237,4NFVP@976,COG1345@1,COG1345@2,COG3291@1,COG3291@2	NA|NA|NA	N	PFAM SMP-30 Gluconolaconase
MAG.T21.18_01903	553178.CAPGI0001_2346	4.7e-34	150.6	Capnocytophaga	ypjD		2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000				Bacteria	1ES25@1016,1I1Z0@117743,4NQ3H@976,COG1694@1,COG1694@2	NA|NA|NA	S	MazG nucleotide pyrophosphohydrolase domain protein
MAG.T21.18_01905	927658.AJUM01000034_gene365	1.9e-93	349.7	Marinilabiliaceae	waaA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K03439	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016		GT30		Bacteria	2FPNI@200643,3XJDE@558415,4NESA@976,COG1519@1,COG1519@2	NA|NA|NA	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
MAG.T21.18_01906	755732.Fluta_2041	1.4e-40	173.3	Cryomorphaceae													Bacteria	1IASC@117743,2EA9Q@1,2PB5U@246874,334E4@2,4NX5I@976	NA|NA|NA		
MAG.T21.18_01907	1124780.ANNU01000005_gene2419	1.5e-134	486.1	Cytophagia	degT												Bacteria	47KX7@768503,4NEBI@976,COG0399@1,COG0399@2	NA|NA|NA	M	Belongs to the DegT DnrJ EryC1 family
MAG.T21.18_01908	755732.Fluta_2059	2.2e-190	671.8	Cryomorphaceae	ugd		1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWQV@117743,2PA9Z@246874,4NE00@976,COG1004@1,COG1004@2	NA|NA|NA	C	PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain
MAG.T21.18_01909	926562.Oweho_1669	8.8e-168	596.3	Cryomorphaceae	rfbB		4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWT7@117743,2PAAK@246874,4NEZX@976,COG0451@1,COG0451@2	NA|NA|NA	M	PFAM NAD dependent epimerase dehydratase family
MAG.T21.18_01911	1122605.KB893647_gene407	5.6e-69	267.3	Sphingobacteriia	wbpD		2.3.1.201	ko:K13018	ko00520,map00520		R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005				Bacteria	1IVB5@117747,4NENC@976,COG0110@1,COG0110@2	NA|NA|NA	S	Hexapeptide repeat of succinyl-transferase
MAG.T21.18_01912	755732.Fluta_2062	7.6e-138	496.9	Cryomorphaceae	bplA		1.1.1.335	ko:K13020	ko00520,map00520		R10140	RC00182	ko00000,ko00001,ko01000,ko01005				Bacteria	1I19J@117743,2PAIR@246874,4NFY3@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, C-terminal alpha beta domain
MAG.T21.18_01916	269798.CHU_2552	1.6e-15	90.5	Cytophagia													Bacteria	47Y04@768503,4PM26@976,COG2885@1,COG2885@2,COG5184@1,COG5184@2	NA|NA|NA	GM	C-terminal domain of CHU protein family
MAG.T21.18_01918	575615.HMPREF0670_00985	1.4e-46	193.0	Bacteroidia	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0022402,GO:0022607,GO:0030145,GO:0030312,GO:0030428,GO:0032506,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044085,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	1.1.1.25,2.1.1.190	ko:K00014,ko:K03215,ko:K06287	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	2FKYZ@200643,4NNXV@976,COG0424@1,COG0424@2	NA|NA|NA	D	Maf-like protein
MAG.T21.18_01919	1283299.AUKG01000005_gene65	6.6e-10	73.2	Rubrobacteria													Bacteria	2HQSY@201174,4CSHH@84995,COG2706@1,COG2706@2	NA|NA|NA	G	FG-GAP repeat
MAG.T21.18_01920	886379.AEWI01000016_gene1522	1.2e-45	190.7	Marinilabiliaceae	ubiA		2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	2FSPD@200643,3XIQE@558415,4NFRM@976,COG0382@1,COG0382@2	NA|NA|NA	H	UbiA prenyltransferase family
MAG.T21.18_01921	1249975.JQLP01000005_gene2479	4.4e-41	174.5	Gillisia	kdsC		3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1I1FS@117743,2P6JR@244698,4NMHD@976,COG1778@1,COG1778@2	NA|NA|NA	S	haloacid dehalogenase-like hydrolase
MAG.T21.18_01922	1211813.CAPH01000006_gene1670	2.5e-32	146.0	Bacteroidia													Bacteria	2FMCQ@200643,4NI4M@976,COG5495@1,COG5495@2	NA|NA|NA	S	NADP oxidoreductase coenzyme F420-dependent
MAG.T21.18_01923	1121904.ARBP01000016_gene5289	4.6e-201	708.4	Cytophagia	ccmF			ko:K02198					ko00000,ko02000	9.B.14.1			Bacteria	47M2N@768503,4NGXI@976,COG1138@1,COG1138@2	NA|NA|NA	O	PFAM Cytochrome c assembly protein
MAG.T21.18_01924	926562.Oweho_0193	2.6e-22	111.7	Flavobacteriia	ccmE			ko:K02197					ko00000				Bacteria	1I9YI@117743,4NN85@976,COG2332@1,COG2332@2	NA|NA|NA	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MAG.T21.18_01926	468059.AUHA01000004_gene2256	8.5e-57	227.6	Sphingobacteriia	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748		ko:K02195	ko02010,map02010	M00259			ko00000,ko00001,ko00002,ko02000	3.A.1.107		iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Bacteria	1INSK@117747,4NFUS@976,COG0755@1,COG0755@2	NA|NA|NA	O	PFAM Cytochrome c assembly protein
MAG.T21.18_01927	504472.Slin_1448	3e-37	162.2	Cytophagia	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193,ko:K02194	ko02010,map02010	M00259			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107		iECO111_1330.ECO111_2936,iYL1228.KPN_02080	Bacteria	47K0P@768503,4NFQV@976,COG2386@1,COG2386@2	NA|NA|NA	O	ABC-type transport system involved in cytochrome c biogenesis permease component
MAG.T21.18_01928	1218074.BAXZ01000010_gene2458	1.4e-24	119.4	Burkholderiaceae				ko:K08983					ko00000				Bacteria	1K72R@119060,1N3XH@1224,2VRQ4@28216,COG3556@1,COG3556@2	NA|NA|NA	S	Predicted membrane protein (DUF2214)
MAG.T21.18_01929	760192.Halhy_5803	5.1e-240	837.8	Sphingobacteriia													Bacteria	1IPS9@117747,4NDX3@976,COG1629@1,COG1629@2,COG4771@2	NA|NA|NA	P	TonB-dependent receptor plug domain
MAG.T21.18_01930	1122176.KB903531_gene2945	1.5e-71	277.3	Bacteroidetes				ko:K06889					ko00000				Bacteria	4NMVZ@976,COG1073@1,COG1073@2	NA|NA|NA	S	alpha beta
MAG.T21.18_01931	497964.CfE428DRAFT_0862	8e-25	120.9	Verrucomicrobia	acpT	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.8.7	ko:K00997,ko:K06133	ko00770,map00770		R01625	RC00002	ko00000,ko00001,ko01000				Bacteria	46T3D@74201,COG2091@1,COG2091@2	NA|NA|NA	H	Belongs to the P-Pant transferase superfamily
MAG.T21.18_01932	693979.Bache_1241	3.4e-98	365.5	Bacteroidaceae	recD2_2		3.1.11.5	ko:K01144					ko00000,ko01000				Bacteria	2FNT1@200643,4AKAI@815,4NDYK@976,COG0507@1,COG0507@2	NA|NA|NA	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
MAG.T21.18_01933	1121129.KB903374_gene554	2.3e-14	86.3	Porphyromonadaceae													Bacteria	22YIM@171551,2C0G9@1,2FN0C@200643,310GM@2,4NHU0@976	NA|NA|NA	S	COG NOG19144 non supervised orthologous group
MAG.T21.18_01935	1127696.HMPREF9134_00769	4e-40	171.4	Porphyromonadaceae	rsmD		2.1.1.171	ko:K08316,ko:K15257			R07234	RC00003	ko00000,ko01000,ko03009,ko03016				Bacteria	22XZ4@171551,2FSR0@200643,4NM7J@976,COG0742@1,COG0742@2	NA|NA|NA	L	RNA methyltransferase, RsmD family
MAG.T21.18_01936	1121895.Q765_01065	1.2e-37	162.9	Flavobacterium	coaD		2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1I1BI@117743,2NT34@237,4NM84@976,COG0669@1,COG0669@2	NA|NA|NA	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAG.T21.18_01937	755732.Fluta_2939	3.8e-13	83.2	Cryomorphaceae				ko:K12057					ko00000,ko02044	3.A.7.11.1			Bacteria	1ICQA@117743,2PBPX@246874,4NNSW@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin-like
MAG.T21.18_01938	1122605.KB893638_gene3434	4.2e-32	144.8	Sphingobacteriia			3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1ITRK@117747,4NS9I@976,COG1051@1,COG1051@2	NA|NA|NA	F	Belongs to the Nudix hydrolase family
MAG.T21.18_01939	1538644.KO02_14210	3.6e-69	268.1	Sphingobacteriia	pyrE		2.4.2.10,4.1.1.23	ko:K00762,ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15560	Bacteria	1IPI8@117747,4NEF8@976,COG0461@1,COG0461@2	NA|NA|NA	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAG.T21.18_01940	926562.Oweho_3145	5.3e-47	194.5	Cryomorphaceae	mnmC		2.1.1.61,2.4.2.29,4.2.1.151	ko:K00773,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110		R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko03016				Bacteria	1HZG3@117743,2PAWQ@246874,4NE5S@976,COG4121@1,COG4121@2	NA|NA|NA	S	S-adenosyl-L-methionine-dependent methyltransferase
MAG.T21.18_01941	984262.SGRA_2537	5.1e-188	664.8	Bacteroidetes													Bacteria	4NEZQ@976,COG3291@1,COG3291@2,COG4447@1,COG4447@2	NA|NA|NA	DZ	Hep Hag repeat protein
MAG.T21.18_01942	927658.AJUM01000034_gene253	1.8e-125	456.1	Marinilabiliaceae	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576		ko:K06885					ko00000				Bacteria	2FMCR@200643,3XIXA@558415,4NE1T@976,COG1078@1,COG1078@2	NA|NA|NA	S	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAG.T21.18_01943	1279009.ADICEAN_02139	9.8e-48	198.7	Cytophagia													Bacteria	47QM2@768503,4PKMD@976,COG1520@1,COG1520@2	NA|NA|NA	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAG.T21.18_01944	1408433.JHXV01000002_gene455	8.2e-89	333.6	Cryomorphaceae	ydfG		1.1.1.276	ko:K05886					ko00000,ko01000				Bacteria	1HY5P@117743,2PAN0@246874,4NE1R@976,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.18_01946	1121007.AUML01000003_gene2616	8.3e-43	180.3	Aquimarina													Bacteria	1I1SZ@117743,2YJ7W@290174,4NRIH@976,COG0457@1,COG0457@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.18_01947	1249975.JQLP01000005_gene2449	7.1e-75	287.7	Gillisia	lpxD		2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1HWJD@117743,2P64V@244698,4NE5G@976,COG1044@1,COG1044@2	NA|NA|NA	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD
MAG.T21.18_01949	1408433.JHXV01000005_gene2237	2.3e-55	223.4	Cryomorphaceae													Bacteria	1I8VS@117743,2ENP2@1,2PB29@246874,33GAE@2,4NZIT@976	NA|NA|NA		
MAG.T21.18_01950	1121481.AUAS01000003_gene3918	8.2e-92	344.0	Cytophagia	wbbL_2			ko:K07011					ko00000				Bacteria	47K2G@768503,4NFP0@976,COG1216@1,COG1216@2	NA|NA|NA	S	PFAM Glycosyl transferase family 2
MAG.T21.18_01951	1203611.KB894541_gene1581	3.8e-43	181.0	Rikenellaceae	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	3.4.13.9,4.2.1.10	ko:K01271,ko:K03785,ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000,ko01002			iIT341.HP1038,iJN746.PP_0560	Bacteria	22UHI@171550,2FR57@200643,4NNHU@976,COG0757@1,COG0757@2	NA|NA|NA	E	Catalyzes a trans-dehydration via an enolate intermediate
MAG.T21.18_01952	926562.Oweho_1099	3.7e-86	325.1	Cryomorphaceae	xerC			ko:K03733,ko:K04763					ko00000,ko03036				Bacteria	1HYPM@117743,2PABU@246874,4NE0E@976,COG4974@1,COG4974@2	NA|NA|NA	D	PFAM Phage integrase, N-terminal SAM-like domain
MAG.T21.18_01954	926562.Oweho_0567	2.9e-97	362.1	Cryomorphaceae													Bacteria	1HX5R@117743,28H6T@1,2PBIQ@246874,2Z7J4@2,4NE4C@976	NA|NA|NA		
MAG.T21.18_01955	1122176.KB903565_gene3200	2.3e-129	469.9	Bacteroidetes													Bacteria	4P1D6@976,COG0308@1,COG0308@2	NA|NA|NA	E	Peptidase family M1 domain
MAG.T21.18_01956	1408433.JHXV01000010_gene542	8.1e-64	251.1	Cryomorphaceae													Bacteria	1IJJS@117743,2PAXM@246874,4NGUV@976,COG3568@1,COG3568@2	NA|NA|NA	S	Endonuclease/Exonuclease/phosphatase family
MAG.T21.18_01957	926562.Oweho_1139	5.6e-62	244.6	Cryomorphaceae													Bacteria	1HZIN@117743,2PB02@246874,4NGVJ@976,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
MAG.T21.18_01958	391596.PBAL39_08906	4.6e-47	194.9	Sphingobacteriia			3.4.21.105	ko:K09650					ko00000,ko01000,ko01002,ko03029				Bacteria	1IS1R@117747,4NIYR@976,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
MAG.T21.18_01959	743722.Sph21_1476	1.1e-168	600.1	Sphingobacteriia	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K03572	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1IPN2@117747,4NDWJ@976,COG0323@1,COG0323@2	NA|NA|NA	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAG.T21.18_01961	755732.Fluta_3099	6.7e-36	156.8	Cryomorphaceae	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02884	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I1YF@117743,2PB2E@246874,4NNPW@976,COG0335@1,COG0335@2	NA|NA|NA	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAG.T21.18_01962	1166018.FAES_3466	5.5e-92	344.0	Cytophagia	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	47MGG@768503,4NF2Q@976,COG0336@1,COG0336@2	NA|NA|NA	J	Belongs to the RNA methyltransferase TrmD family
MAG.T21.18_01963	1408433.JHXV01000002_gene292	4.1e-21	108.6	Cryomorphaceae													Bacteria	1IMS2@117743,2A607@1,2PBUU@246874,30USF@2,4PFQT@976	NA|NA|NA		
MAG.T21.18_01964	886379.AEWI01000013_gene2093	3e-102	378.6	Marinilabiliaceae	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000			iIT341.HP0663,iJN678.aroC	Bacteria	2FNGP@200643,3XIUH@558415,4NDXJ@976,COG0082@1,COG0082@2	NA|NA|NA	E	Chorismate synthase
MAG.T21.18_01965	926562.Oweho_0858	7.4e-94	350.1	Cryomorphaceae	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXUY@117743,2PAIW@246874,4NFVZ@976,COG0176@1,COG0176@2	NA|NA|NA	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MAG.T21.18_01966	926562.Oweho_0859	3.1e-48	198.4	Cryomorphaceae	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	1HX8T@117743,2PASB@246874,4NDZR@976,COG0009@1,COG0009@2	NA|NA|NA	J	TIGRFAM Sua5 YciO YrdC YwlC family protein
MAG.T21.18_01967	1227739.Hsw_0294	5.7e-99	368.2	Cytophagia	nnrD		4.2.1.136,5.1.99.6	ko:K17758,ko:K17759					ko00000,ko01000				Bacteria	47JYX@768503,4NG2F@976,COG0062@1,COG0062@2,COG0063@1,COG0063@2	NA|NA|NA	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAG.T21.18_01971	411154.GFO_0668	4.1e-65	254.6	Flavobacteriia	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573					ko00000,ko01000				Bacteria	1HXFE@117743,4NFCU@976,COG2518@1,COG2518@2	NA|NA|NA	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MAG.T21.18_01972	1250005.PHEL85_0226	2.2e-91	342.4	Polaribacter	gnnA			ko:K09949					ko00000			iAF987.Gmet_2352	Bacteria	1HXSP@117743,3VVK2@52959,4NEC6@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.18_01973	1408433.JHXV01000036_gene268	5e-34	151.8	Cryomorphaceae													Bacteria	1IAKI@117743,2FG80@1,2PB7R@246874,3484C@2,4P5E2@976	NA|NA|NA		
MAG.T21.18_01974	755732.Fluta_0259	5.4e-134	484.6	Cryomorphaceae	wcaJ	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.187,2.7.8.40	ko:K05946,ko:K21303	ko05111,map05111				ko00000,ko00001,ko01000,ko01003,ko01005		GT26		Bacteria	1HXE1@117743,2PAGQ@246874,4NFIA@976,COG1086@1,COG1086@2,COG2148@1,COG2148@2	NA|NA|NA	M	CoA-binding domain
MAG.T21.18_01975	1120965.AUBV01000007_gene2564	1.4e-116	426.0	Cytophagia	hbdA		1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120		R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000				Bacteria	47NRU@768503,4NGU8@976,COG1250@1,COG1250@2	NA|NA|NA	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
MAG.T21.18_01976	1189612.A33Q_3699	1.6e-53	216.5	Cytophagia			2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000				Bacteria	47YS5@768503,4P2G2@976,COG2227@1,COG2227@2	NA|NA|NA	H	Methyltransferase domain
MAG.T21.18_01977	760192.Halhy_5504	1.4e-31	142.9	Bacteroidetes				ko:K03830					ko00000,ko01000				Bacteria	4PP1Y@976,COG1247@1,COG1247@2	NA|NA|NA	M	FR47-like protein
MAG.T21.18_01978	761193.Runsl_3972	3e-18	100.1	Cytophagia													Bacteria	47MIS@768503,4NHT8@976,COG5305@1,COG5305@2	NA|NA|NA	S	Dolichyl-phosphate-mannose-protein mannosyltransferase
MAG.T21.18_01979	1183438.GKIL_0470	4.6e-84	318.2	Cyanobacteria	arnA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315	1.1.1.305,2.1.2.13,5.1.3.2	ko:K01784,ko:K10011,ko:K12449,ko:K21332	ko00052,ko00520,ko00523,ko01100,ko01130,ko01503,map00052,map00520,map00523,map01100,map01130,map01503	M00361,M00362,M00632,M00721,M00761	R00291,R01384,R01386,R02984,R07658,R07660,R11472	RC00026,RC00289,RC00508,RC01575,RC01811,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005			iPC815.YPO2420,iSFV_1184.SFV_2325	Bacteria	1GBK7@1117,COG0451@1,COG0451@2	NA|NA|NA	M	Polysaccharide biosynthesis protein
MAG.T21.18_01980	1183438.GKIL_0471	1.1e-37	163.7	Bacteria			2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111		R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019		GT2		Bacteria	COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase, family 2
MAG.T21.18_01981	869213.JCM21142_72882	6e-33	147.9	Bacteroidetes													Bacteria	2CI1G@1,2Z7JA@2,4NF1T@976	NA|NA|NA	S	Domain of unknown function (DUF4294)
MAG.T21.18_01982	1120965.AUBV01000013_gene1362	4.9e-189	667.5	Cytophagia			6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	47M7U@768503,4NM1W@976,COG4770@1,COG4770@2	NA|NA|NA	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding
MAG.T21.18_01984	1237149.C900_05299	1.8e-34	152.9	Bacteroidetes				ko:K01175					ko00000,ko01000				Bacteria	4NP3H@976,COG1073@1,COG1073@2	NA|NA|NA	S	Alpha/beta hydrolase family
MAG.T21.18_01985	926562.Oweho_0814	1.5e-94	352.4	Cryomorphaceae	sucC		6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYKT@117743,2PA8G@246874,4NFHA@976,COG0045@1,COG0045@2	NA|NA|NA	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MAG.T21.18_01986	762903.Pedsa_1745	3e-76	291.6	Sphingobacteriia	lolD			ko:K09810	ko02010,map02010	M00255			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125			Bacteria	1IPBQ@117747,4NGDU@976,COG1136@1,COG1136@2	NA|NA|NA	V	Part of the ABC transporter complex LolCDE involved in the translocation of
MAG.T21.18_01988	929556.Solca_4457	2.1e-09	69.7	Bacteroidetes													Bacteria	2EM8X@1,33EY2@2,4NYIN@976	NA|NA|NA		
MAG.T21.18_01992	290315.Clim_2415	4.2e-33	147.9	Chlorobi	sixA			ko:K08296					ko00000,ko01000				Bacteria	1FE6K@1090,COG2062@1,COG2062@2	NA|NA|NA	T	PFAM Phosphoglycerate mutase
MAG.T21.18_01993	925409.KI911562_gene272	4.4e-27	127.5	Sphingobacteriia				ko:K06929					ko00000				Bacteria	1ITJY@117747,4NSE8@976,COG1832@1,COG1832@2	NA|NA|NA	S	CoA binding domain
MAG.T21.18_01994	1122621.ATZA01000017_gene3928	3e-86	325.1	Sphingobacteriia	lpxH		3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IQAN@117747,4NFD8@976,COG2908@1,COG2908@2	NA|NA|NA	S	Phosphoesterase
MAG.T21.18_01995	1408433.JHXV01000037_gene2580	4e-29	134.4	Cryomorphaceae													Bacteria	1I2T2@117743,2PB51@246874,4NQ3Z@976,COG4068@1,COG4068@2	NA|NA|NA		
MAG.T21.18_01996	980584.AFPB01000141_gene2902	9.5e-155	553.5	Flavobacteriia													Bacteria	1HWM1@117743,4NFK5@976,COG1696@1,COG1696@2	NA|NA|NA	M	Membrane protein involved in D-alanine export
MAG.T21.18_01997	641524.ADICYQ_5832	1.3e-46	193.7	Cytophagia													Bacteria	47TTV@768503,4NNAQ@976,COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
MAG.T21.18_01998	1250005.PHEL85_2704	8.1e-36	156.8	Polaribacter													Bacteria	1I2YC@117743,3VWFV@52959,4NQ5T@976,COG1846@1,COG1846@2	NA|NA|NA	K	helix_turn_helix multiple antibiotic resistance protein
MAG.T21.18_01999	517418.Ctha_2249	3e-115	422.2	Bacteria	phoD		3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	COG3540@1,COG3540@2	NA|NA|NA	P	PhoD-like phosphatase
MAG.T21.18_02000	1121904.ARBP01000015_gene149	9.7e-98	363.6	Cytophagia													Bacteria	47N8J@768503,4NI60@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.18_02001	1434325.AZQN01000001_gene74	2.7e-150	538.9	Cytophagia	rhlE		3.6.4.13	ko:K11927	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	47J9E@768503,4NEVI@976,COG0513@1,COG0513@2	NA|NA|NA	L	Belongs to the DEAD box helicase family
MAG.T21.18_02002	313606.M23134_02237	1.1e-45	193.0	Cytophagia				ko:K14274,ko:K20276	ko00040,ko02024,map00040,map02024		R02427	RC00713	ko00000,ko00001,ko01000				Bacteria	47N8F@768503,4NJ9V@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2,COG3386@1,COG3386@2,COG4932@1,COG4932@2	NA|NA|NA	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_02003	1123058.KB894238_gene1880	1e-28	133.3	Flavobacteriia			2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230		R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009				Bacteria	1I3TF@117743,4NRRN@976,COG0317@1,COG0317@2	NA|NA|NA	KT	Phosphohydrolase
MAG.T21.18_02004	1122176.KB903569_gene3483	4.7e-114	419.1	Bacteroidetes													Bacteria	4NEH2@976,COG5337@1,COG5337@2	NA|NA|NA	M	sodium ion export across plasma membrane
MAG.T21.18_02005	1237149.C900_03094	1.4e-231	809.3	Cytophagia													Bacteria	47MEE@768503,4NFIY@976,COG0457@1,COG0457@2	NA|NA|NA	S	Peptidase family M49
MAG.T21.18_02006	1317122.ATO12_21320	2.2e-53	215.3	Aquimarina				ko:K07095					ko00000				Bacteria	1I19W@117743,2YGXJ@290174,4NM4G@976,COG0622@1,COG0622@2	NA|NA|NA	S	Calcineurin-like phosphoesterase superfamily domain
MAG.T21.18_02007	509635.N824_06940	6.5e-13	80.1	Sphingobacteriia	divIC			ko:K05589,ko:K12065,ko:K13052					ko00000,ko02044,ko03036	3.A.7.11.1			Bacteria	1IYQM@117747,4NURQ@976,COG2919@1,COG2919@2	NA|NA|NA	D	Septum formation initiator
MAG.T21.18_02009	504472.Slin_1395	4.1e-44	184.5	Cytophagia	slyD	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042026,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03775					ko00000,ko01000,ko03110				Bacteria	47QER@768503,4NM29@976,COG1047@1,COG1047@2	NA|NA|NA	O	Peptidyl-prolyl cis-trans isomerase
MAG.T21.18_02011	1121889.AUDM01000003_gene2303	3.9e-13	81.6	Flavobacteriia													Bacteria	1I8M4@117743,4P2MC@976,COG4188@1,COG4188@2	NA|NA|NA	S	Chlorophyllase
MAG.T21.18_02012	1122176.KB903561_gene3586	1.5e-31	142.9	Sphingobacteriia													Bacteria	1IXPV@117747,4NI82@976,COG2353@1,COG2353@2	NA|NA|NA	S	YceI-like domain
MAG.T21.18_02013	1122176.KB903561_gene3587	2.9e-67	263.8	Sphingobacteriia													Bacteria	1IWR7@117747,4NJMF@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2	NA|NA|NA	T	Y_Y_Y domain
MAG.T21.18_02014	1123248.KB893348_gene195	1.1e-53	216.9	Sphingobacteriia	lytT			ko:K02477,ko:K07705,ko:K11641	ko02020,map02020	M00492,M00494			ko00000,ko00001,ko00002,ko02022				Bacteria	1ISF2@117747,4NGBF@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator receiver domain
MAG.T21.18_02016	1122176.KB903561_gene3589	1.4e-40	173.3	Sphingobacteriia													Bacteria	1IXW6@117747,4PEWN@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_02017	1279009.ADICEAN_02200	8.5e-15	86.7	Bacteria													Bacteria	COG3748@1,COG3748@2	NA|NA|NA	S	Urate oxidase N-terminal
MAG.T21.18_02018	1336803.PHEL49_1455	1.2e-07	63.2	Polaribacter													Bacteria	1I61D@117743,2E3Q9@1,32YN7@2,3VWQW@52959,4NWH3@976	NA|NA|NA	S	tRNA_anti-like
MAG.T21.18_02019	929713.NIASO_14050	2.1e-39	169.1	Sphingobacteriia													Bacteria	1IY6E@117747,4NSJH@976,COG2353@1,COG2353@2	NA|NA|NA	S	PFAM Lipid polyisoprenoid-binding, YceI-like
MAG.T21.18_02020	1122176.KB903561_gene3593	1e-88	333.6	Sphingobacteriia	pagC			ko:K07804	ko02020,map02020				ko00000,ko00001				Bacteria	1IXJN@117747,4NE33@976,COG3637@1,COG3637@2	NA|NA|NA	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MAG.T21.18_02021	452637.Oter_3626	2.5e-62	246.1	Opitutae	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K06212,ko:K06402					ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3			Bacteria	3K9SZ@414999,46SM2@74201,COG0517@1,COG0517@2,COG1994@1,COG1994@2	NA|NA|NA	S	Peptidase M50
MAG.T21.18_02022	1453500.AT05_10200	3.3e-27	129.0	Flavobacteriia													Bacteria	1HYAY@117743,4NHBB@976,COG0589@1,COG0589@2	NA|NA|NA	T	Universal stress protein
MAG.T21.18_02024	929562.Emtol_0844	8e-19	100.1	Cytophagia													Bacteria	2AXFQ@1,31PF8@2,47SZR@768503,4NQN3@976	NA|NA|NA		
MAG.T21.18_02025	755732.Fluta_2738	9.6e-189	666.4	Cryomorphaceae	gltA		2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1HWVX@117743,2PB6G@246874,4NFXK@976,COG0372@1,COG0372@2	NA|NA|NA	C	Belongs to the citrate synthase family
MAG.T21.18_02026	1453500.AT05_01715	7e-41	174.1	Flavobacteriia													Bacteria	1I16Q@117743,4NM6B@976,COG2143@1,COG2143@2	NA|NA|NA	O	COG2143 Thioredoxin-related protein
MAG.T21.18_02027	1227739.Hsw_2410	1e-178	633.3	Cytophagia	dtpT			ko:K03305					ko00000	2.A.17			Bacteria	47JX4@768503,4NE8R@976,COG3104@1,COG3104@2	NA|NA|NA	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial
MAG.T21.18_02028	1227739.Hsw_0094	3.2e-186	658.7	Cytophagia	dpp		3.4.14.5	ko:K01278	ko04974,map04974				ko00000,ko00001,ko01000,ko01002,ko04090,ko04147				Bacteria	47KF8@768503,4NETS@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MAG.T21.18_02029	762903.Pedsa_0201	4.2e-109	401.7	Sphingobacteriia													Bacteria	1J0M5@117747,4PKN6@976,COG0477@1,COG0477@2	NA|NA|NA	EGP	PFAM Major Facilitator Superfamily
MAG.T21.18_02030	926562.Oweho_3146	3.1e-08	65.1	Flavobacteriia													Bacteria	1I349@117743,2E0HI@1,32W3C@2,4NQ7D@976	NA|NA|NA		
MAG.T21.18_02031	926562.Oweho_0897	4.9e-46	191.4	Cryomorphaceae	SEN0012												Bacteria	1HXF0@117743,2PAYY@246874,4NGT3@976,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
MAG.T21.18_02032	583355.Caka_2510	3.5e-09	68.2	Bacteria	ybaY			ko:K03668,ko:K09914					ko00000				Bacteria	COG3126@1,COG3126@2,COG3187@1,COG3187@2	NA|NA|NA	S	Type III secretion system lipoprotein chaperone (YscW)
MAG.T21.18_02033	745718.JADT01000001_gene1785	2e-131	475.7	Flavobacteriia	dnaN		2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1HX2U@117743,4NESB@976,COG0592@1,COG0592@2	NA|NA|NA	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAG.T21.18_02034	1408433.JHXV01000018_gene3791	1.6e-26	127.1	Cryomorphaceae													Bacteria	1I9ID@117743,2E7J5@1,2PB0F@246874,3321E@2,4NWSR@976	NA|NA|NA		
MAG.T21.18_02035	926562.Oweho_1585	6e-103	381.7	Cryomorphaceae	gldG			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1HX9X@117743,2PAPC@246874,4NF62@976,COG3225@1,COG3225@2	NA|NA|NA	N	ABC-type uncharacterized transport system
MAG.T21.18_02036	1408473.JHXO01000011_gene3063	2.8e-54	219.2	Bacteroidia	gldG			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2FQ8Z@200643,4NF62@976,COG1277@1,COG1277@2,COG3225@1,COG3225@2	NA|NA|NA	N	ABC-type uncharacterized transport system
MAG.T21.18_02038	398720.MED217_08205	4e-23	114.0	Leeuwenhoekiella			1.5.1.40	ko:K06988					ko00000,ko01000				Bacteria	1I40Y@117743,2XJNC@283735,4NSV0@976,COG1359@1,COG1359@2	NA|NA|NA	S	Antibiotic biosynthesis monooxygenase
MAG.T21.18_02039	313596.RB2501_13584	1.2e-58	233.4	Flavobacteriia	fjo14			ko:K22205					ko00000,ko01000				Bacteria	1HX11@117743,4NG9Y@976,COG1912@1,COG1912@2	NA|NA|NA	S	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
MAG.T21.18_02040	880526.KE386488_gene1776	2.3e-104	385.6	Rikenellaceae	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06217					ko00000				Bacteria	22V0M@171550,2FMIF@200643,4NDYV@976,COG1702@1,COG1702@2	NA|NA|NA	T	Phosphate starvation-inducible protein PhoH
MAG.T21.18_02041	1008457.BAEX01000115_gene1418	1.4e-106	392.9	Myroides	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K03566,ko:K13713	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000				Bacteria	1HWM5@117743,47HHJ@76831,4NF1Z@976,COG0152@1,COG0152@2	NA|NA|NA	F	SAICAR synthetase
MAG.T21.18_02042	620914.JH621301_gene3562	3.7e-59	236.5	Aquimarina			3.4.21.107,3.4.21.50	ko:K01337,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1I89F@117743,2YGTW@290174,4PKT1@976,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like peptidase domain
MAG.T21.18_02043	1408433.JHXV01000010_gene620	7.5e-132	478.0	Cryomorphaceae													Bacteria	1HYK6@117743,2PA4T@246874,4NEGF@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_02044	509635.N824_04010	5.5e-154	552.0	Sphingobacteriia				ko:K09800					ko00000,ko02000				Bacteria	1IRAR@117747,4NEJQ@976,COG2982@1,COG2982@2	NA|NA|NA	M	AsmA-like C-terminal region
MAG.T21.18_02045	1237149.C900_02770	9.7e-136	490.3	Cytophagia	gltP												Bacteria	47KI1@768503,4NDUU@976,COG1301@1,COG1301@2	NA|NA|NA	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAG.T21.18_02046	1279009.ADICEAN_04130	7e-152	544.7	Cytophagia				ko:K07003					ko00000				Bacteria	47JQA@768503,4NE0M@976,COG1033@1,COG1033@2	NA|NA|NA	S	COGs COG1033 exporter of the RND superfamily protein
MAG.T21.18_02047	1408433.JHXV01000005_gene2290	3.2e-13	84.0	Cryomorphaceae				ko:K02453	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	1IKE6@117743,2PB2R@246874,4PMDU@976,COG1729@1,COG1729@2	NA|NA|NA	S	WG containing repeat
MAG.T21.18_02048	313606.M23134_00148	5.3e-179	636.0	Cytophagia													Bacteria	47MGN@768503,4NDZQ@976,COG3291@1,COG3291@2,COG3386@1,COG3386@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.18_02049	1356852.N008_11045	3e-23	115.5	Bacteroidetes	speE		2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000				Bacteria	4NPK5@976,COG0421@1,COG0421@2	NA|NA|NA	E	Spermidine synthase
MAG.T21.18_02050	985255.APHJ01000040_gene277	1.2e-213	749.2	Gillisia	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470					ko00000,ko01000,ko03032,ko03400				Bacteria	1HX0K@117743,2P630@244698,4NE0P@976,COG0187@1,COG0187@2	NA|NA|NA	L	TopoisomeraseII
MAG.T21.18_02052	641526.ADIWIN_0056	1.9e-179	637.9	Flavobacteriia			3.4.21.72	ko:K01347					ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1HXFW@117743,4NG93@976,COG4886@1,COG4886@2,COG4932@1,COG4932@2	NA|NA|NA	M	regulator of chromosome condensation, RCC1
MAG.T21.18_02053	755732.Fluta_2899	7.9e-74	285.8	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1HY1V@117743,2PBEH@246874,4NDZC@976,COG3291@1,COG3291@2	NA|NA|NA	M	SPTR CHU large protein
MAG.T21.18_02054	755732.Fluta_1778	7.7e-169	601.7	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1IG7A@117743,2PBJ3@246874,4PI0B@976,COG3291@1,COG3291@2,COG4935@1,COG4935@2	NA|NA|NA	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_02055	1408433.JHXV01000010_gene583	1.2e-31	144.4	Bacteria			2.1.1.72,3.1.4.46,3.2.1.1	ko:K00571,ko:K01126,ko:K01176	ko00500,ko00564,ko01100,ko04973,map00500,map00564,map01100,map04973		R01030,R01470,R02108,R02112,R11262	RC00017,RC00425	ko00000,ko00001,ko01000,ko02048		GH13		Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_02056	1408433.JHXV01000010_gene584	1.2e-40	173.3	Cryomorphaceae				ko:K03088					ko00000,ko03021				Bacteria	1I1A4@117743,2PBNV@246874,4NQCH@976,COG1595@1,COG1595@2	NA|NA|NA	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family
MAG.T21.18_02057	1453500.AT05_00665	1.7e-142	512.3	Flavobacteriia	mdh		1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWSA@117743,4NEJ7@976,COG0039@1,COG0039@2	NA|NA|NA	C	Catalyzes the reversible oxidation of malate to oxaloacetate
MAG.T21.18_02058	1408433.JHXV01000004_gene3388	6.6e-134	485.0	Cryomorphaceae			1.11.1.7	ko:K19511,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000				Bacteria	1I54C@117743,2PAIC@246874,4NFV5@976,COG2931@1,COG2931@2	NA|NA|NA	Q	PFAM FG-GAP repeat
MAG.T21.18_02059	1501391.LG35_03450	2.2e-221	776.2	Rikenellaceae	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944		ko:K03072,ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7			Bacteria	22U2I@171550,2FMPX@200643,4NE1X@976,COG0341@1,COG0341@2,COG0342@1,COG0342@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MAG.T21.18_02060	391587.KAOT1_21976	1e-07	62.8	Flavobacteriia	tatA			ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1I40K@117743,4NSAK@976,COG1826@1,COG1826@2	NA|NA|NA	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MAG.T21.18_02061	392500.Swoo_4588	1.2e-68	266.9	Shewanellaceae	yrbG			ko:K07301					ko00000,ko02000	2.A.19.5			Bacteria	1MU3R@1224,1RMRD@1236,2Q8QS@267890,COG0530@1,COG0530@2	NA|NA|NA	P	PFAM sodium calcium exchanger membrane region
MAG.T21.18_02062	755732.Fluta_3949	1.9e-308	1064.7	Cryomorphaceae	glnA		6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	1HWKZ@117743,2PA6N@246874,4NG2B@976,COG3968@1,COG3968@2	NA|NA|NA	S	Glutamine synthetase type III N terminal
MAG.T21.18_02063	1408473.JHXO01000006_gene1037	1.7e-117	430.3	Bacteroidia	pal			ko:K03640					ko00000,ko02000	2.C.1.2			Bacteria	2FPQX@200643,4NE6G@976,COG2885@1,COG2885@2	NA|NA|NA	MU	Belongs to the ompA family
MAG.T21.18_02064	203275.BFO_1374	3.8e-162	577.8	Porphyromonadaceae	purM		6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000				Bacteria	22VWI@171551,2FM0G@200643,4NE4E@976,COG0150@1,COG0150@2	NA|NA|NA	F	Phosphoribosylformylglycinamidine cyclo-ligase
MAG.T21.18_02065	742766.HMPREF9455_00018	4.5e-117	427.9	Porphyromonadaceae	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02835,ko:K15034					ko00000,ko03012				Bacteria	22VUT@171551,2FNKW@200643,4NF72@976,COG0216@1,COG0216@2	NA|NA|NA	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAG.T21.18_02066	385682.AFSL01000062_gene1601	3.8e-79	301.6	Marinilabiliaceae	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS17585	Bacteria	2FPJM@200643,3XJVW@558415,4NE12@976,COG0284@1,COG0284@2	NA|NA|NA	F	Orotidine 5'-phosphate decarboxylase / HUMPS family
MAG.T21.18_02067	1122176.KB903560_gene3540	6.6e-102	377.9	Sphingobacteriia													Bacteria	1INN1@117747,28HQ3@1,2Z7XW@2,4NF9H@976	NA|NA|NA	S	Protein of unknown function (DUF2851)
MAG.T21.18_02068	755732.Fluta_2145	5.1e-10	70.1	Bacteria	pspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944		ko:K03973					ko00000,ko02048,ko03000				Bacteria	COG1983@1,COG1983@2	NA|NA|NA	KT	positive regulation of macromolecule biosynthetic process
MAG.T21.18_02069	313603.FB2170_15533	2.8e-16	92.8	Flavobacteriia	flhB			ko:K02401,ko:K13820	ko02040,map02040				ko00000,ko00001,ko02035,ko02044	3.A.6.2			Bacteria	1I174@117743,4NMN3@976,COG1377@1,COG1377@2	NA|NA|NA	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MAG.T21.18_02070	1408433.JHXV01000001_gene732	8.8e-131	474.2	Cryomorphaceae			2.7.11.1	ko:K14949	ko05152,map05152				ko00000,ko00001,ko01000,ko01001				Bacteria	1IMQQ@117743,2PBFK@246874,4PMJW@976,COG5010@1,COG5010@2	NA|NA|NA	U	COG0457 FOG TPR repeat
MAG.T21.18_02071	1341155.FSS13T_04240	3.8e-45	188.3	Flavobacterium	folK		2.5.1.15,2.7.1.113,2.7.6.3,3.5.4.16,4.1.2.25	ko:K00796,ko:K00950,ko:K01495,ko:K13940,ko:K13941,ko:K15518	ko00230,ko00790,ko01100,map00230,map00790,map01100	M00126,M00840,M00841,M00842,M00843	R00428,R01967,R03066,R03067,R03503,R03504,R04639,R05046,R05048	RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWTH@117743,2NTCX@237,4NGE8@976,COG0801@1,COG0801@2,COG1428@1,COG1428@2	NA|NA|NA	FH	7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
MAG.T21.18_02072	1122605.KB893625_gene1587	6.1e-29	134.0	Sphingobacteriia	folK		2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0041	Bacteria	1ISW1@117747,4NGE8@976,COG0801@1,COG0801@2	NA|NA|NA	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MAG.T21.18_02073	468059.AUHA01000003_gene1428	2.3e-142	512.7	Sphingobacteriia	sppA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564		ko:K04773					ko00000,ko01000,ko01002				Bacteria	1IP6H@117747,4NES1@976,COG0616@1,COG0616@2	NA|NA|NA	OU	signal peptide peptidase SppA, 67K type
MAG.T21.18_02074	1121957.ATVL01000014_gene1459	4.3e-14	86.3	Cytophagia													Bacteria	47VHU@768503,4PHUI@976,COG5563@1,COG5563@2	NA|NA|NA		
MAG.T21.18_02075	1168034.FH5T_08365	2.6e-61	242.3	Bacteroidia	LA2027												Bacteria	2BVTQ@1,2FWJ5@200643,2Z7J9@2,4NGSY@976	NA|NA|NA	S	Protein of unknown function (DUF2797)
MAG.T21.18_02076	755732.Fluta_1040	1.1e-182	646.4	Cryomorphaceae													Bacteria	1IJBB@117743,2PAC6@246874,4PKJY@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	GH3 auxin-responsive promoter
MAG.T21.18_02078	755732.Fluta_3275	0.0	1172.9	Cryomorphaceae	clpC			ko:K03696	ko01100,map01100				ko00000,ko03110				Bacteria	1HWVR@117743,2PAAQ@246874,4NE1J@976,COG0542@1,COG0542@2	NA|NA|NA	O	ATPase family associated with various cellular activities (AAA)
MAG.T21.18_02079	1429851.X548_20065	3.2e-212	745.0	Xanthomonadales	dcp	GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414					ko00000,ko01000,ko01002				Bacteria	1MU1K@1224,1RMXI@1236,1X3Q6@135614,COG0339@1,COG0339@2	NA|NA|NA	E	Dipeptidyl carboxypeptidase
MAG.T21.18_02080	1406840.Q763_00305	2.8e-158	565.1	Flavobacterium	rarA			ko:K07478					ko00000				Bacteria	1HXHG@117743,2NSB6@237,4NEV8@976,COG2256@1,COG2256@2	NA|NA|NA	L	ATPase (AAA
MAG.T21.18_02082	1408433.JHXV01000005_gene2517	3.8e-35	156.4	Cryomorphaceae													Bacteria	1ICNC@117743,2BJHF@1,2PB7V@246874,32DUB@2,4P9RZ@976	NA|NA|NA		
MAG.T21.18_02083	153721.MYP_1564	1.7e-14	87.4	Cytophagia													Bacteria	2F2AF@1,33V8E@2,47USP@768503,4P2D9@976	NA|NA|NA		
MAG.T21.18_02084	1124780.ANNU01000008_gene2724	2.7e-33	147.9	Cytophagia	ykkD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944		ko:K11741,ko:K18925		M00712			ko00000,ko00002,ko02000	2.A.7.1,2.A.7.1.5			Bacteria	47R8W@768503,4NQ4U@976,COG2076@1,COG2076@2	NA|NA|NA	P	PFAM small multidrug resistance protein
MAG.T21.18_02085	906888.JCM19314_648	2.9e-08	65.5	Flavobacteriia													Bacteria	1IBGF@117743,2DRWH@1,33DE8@2,4NYFG@976	NA|NA|NA	S	Protein of unknown function (DUF2628)
MAG.T21.18_02086	1185876.BN8_06176	3.6e-71	275.0	Cytophagia	proC	GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000				Bacteria	47MGF@768503,4NGIG@976,COG0345@1,COG0345@2	NA|NA|NA	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MAG.T21.18_02087	755732.Fluta_3902	8.2e-149	534.3	Cryomorphaceae													Bacteria	1INKT@117743,2PA4S@246874,4NE6G@976,COG0823@1,COG0823@2,COG2885@1,COG2885@2,COG3063@1,COG3063@2	NA|NA|NA	MNU	OmpA family
MAG.T21.18_02088	761193.Runsl_0201	1.3e-73	282.7	Cytophagia	queE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100		R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016				Bacteria	47MB1@768503,4NESC@976,COG0602@1,COG0602@2	NA|NA|NA	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MAG.T21.18_02089	1349785.BAUG01000054_gene2431	4.4e-36	157.9	Flavobacteriia													Bacteria	1I08A@117743,28H8R@1,2Z7KJ@2,4NGZN@976	NA|NA|NA		
MAG.T21.18_02090	641524.ADICYQ_0491	6.6e-09	67.4	Cytophagia													Bacteria	2EN2B@1,33FQI@2,47SN0@768503,4NY51@976	NA|NA|NA		
MAG.T21.18_02091	1227739.Hsw_1973	1e-134	487.3	Cytophagia													Bacteria	47M7Z@768503,4NF5T@976,COG2866@1,COG2866@2	NA|NA|NA	E	Zinc carboxypeptidase
MAG.T21.18_02092	307480.IW16_23600	1.7e-36	160.2	Chryseobacterium													Bacteria	1IIHQ@117743,3ZNMC@59732,4NIP4@976,COG5184@1,COG5184@2	NA|NA|NA	DZ	Regulator of chromosome condensation (RCC1) repeat
MAG.T21.18_02093	1121899.Q764_12460	5.1e-24	119.0	Flavobacteriia													Bacteria	1I7UZ@117743,2EY17@1,33RA6@2,4P18T@976	NA|NA|NA		
MAG.T21.18_02095	1123277.KB893217_gene4656	1.4e-262	912.1	Cytophagia	acsA	GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004			iE2348C_1286.E2348C_4392,iYL1228.KPN_04478	Bacteria	47JMW@768503,4NEAD@976,COG0365@1,COG0365@2	NA|NA|NA	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MAG.T21.18_02096	331678.Cphamn1_1563	4.5e-47	194.9	Chlorobi													Bacteria	1FEZD@1090,COG1680@1,COG1680@2	NA|NA|NA	V	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.18_02097	1453500.AT05_05540	1.3e-56	225.7	Flavobacteriia			3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120		R03024	RC00151	ko00000,ko00001,ko01000				Bacteria	1I2FP@117743,4NNYH@976,COG0647@1,COG0647@2	NA|NA|NA	G	Phosphoheptose isomerase
MAG.T21.18_02100	1288963.ADIS_1811	1.7e-98	365.9	Cytophagia	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000				Bacteria	47K0S@768503,4NEJP@976,COG0190@1,COG0190@2	NA|NA|NA	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAG.T21.18_02102	314278.NB231_15018	2.8e-17	96.7	Gammaproteobacteria													Bacteria	1NHWC@1224,1SRH7@1236,2CM5J@1,33NXS@2	NA|NA|NA		
MAG.T21.18_02105	886379.AEWI01000058_gene2583	1.7e-13	82.0	Bacteroidia													Bacteria	2FVU0@200643,4NYCZ@976,COG3668@1,COG3668@2	NA|NA|NA	S	ParE toxin of type II toxin-antitoxin system, parDE
MAG.T21.18_02107	1452718.JBOY01000027_gene82	1.3e-184	652.9	Gammaproteobacteria	yfjM												Bacteria	1R5X1@1224,1RYM1@1236,COG1479@1,COG1479@2,COG3472@1,COG3472@2	NA|NA|NA	S	Protein of unknown function DUF262
MAG.T21.18_02108	746697.Aeqsu_0597	1.3e-177	629.4	Flavobacteriia	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9			Bacteria	1HXT4@117743,4NDZ2@976,COG0541@1,COG0541@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAG.T21.18_02109	485918.Cpin_3623	1.3e-260	907.1	Sphingobacteriia	pelX			ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	1J0N1@117747,4PKBQ@976,COG2304@1,COG2304@2,COG2373@1,COG2373@2,COG2755@1,COG2755@2,COG3209@1,COG3209@2,COG5492@1,COG5492@2	NA|NA|NA	M	conserved repeat domain protein
MAG.T21.18_02110	927658.AJUM01000022_gene1004	2e-44	186.4	Marinilabiliaceae													Bacteria	2FTFG@200643,3XJ5W@558415,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_02111	755732.Fluta_3355	7.9e-92	345.1	Cryomorphaceae				ko:K03640					ko00000,ko02000	2.C.1.2			Bacteria	1HXNY@117743,2PBHG@246874,4NE6G@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_02112	426114.THI_2725	1.1e-70	273.5	unclassified Burkholderiales	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700		ko:K09861					ko00000				Bacteria	1KIZ9@119065,1MUAF@1224,2VH23@28216,COG3022@1,COG3022@2	NA|NA|NA	S	Belongs to the UPF0246 family
MAG.T21.18_02113	760192.Halhy_3108	2.6e-25	121.7	Sphingobacteriia													Bacteria	1IZMU@117747,4NW3X@976,COG5646@1,COG5646@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_02114	1408433.JHXV01000033_gene1151	1e-57	231.1	Cryomorphaceae													Bacteria	1HXE7@117743,2PB0U@246874,4NGNF@976,COG2259@1,COG2259@2	NA|NA|NA	S	DoxX family
MAG.T21.18_02116	926556.Echvi_0679	1.9e-38	166.8	Bacteroidetes	yhjY			ko:K12287,ko:K12686					ko00000,ko02000,ko02044	1.B.12.8			Bacteria	4NMBF@976,COG5571@1,COG5571@2	NA|NA|NA	N	Psort location OuterMembrane, score
MAG.T21.18_02117	1150600.ADIARSV_2453	7.9e-11	74.7	Bacteroidetes													Bacteria	2EHJH@1,32W49@2,4NTI9@976	NA|NA|NA		
MAG.T21.18_02118	1004149.AFOE01000038_gene900	2.3e-89	335.5	Flavobacteriia	nadE		6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYCI@117743,4NEXG@976,COG0171@1,COG0171@2	NA|NA|NA	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MAG.T21.18_02119	1408813.AYMG01000003_gene2839	3.6e-30	138.7	Sphingobacteriia													Bacteria	1IX15@117747,2CJVV@1,32SAW@2,4NSKH@976	NA|NA|NA	S	Outer membrane protein beta-barrel domain
MAG.T21.18_02120	1408473.JHXO01000006_gene1089	5e-41	175.3	Bacteroidia	gldB												Bacteria	2FMM9@200643,4NFZP@976,COG5504@1,COG5504@2	NA|NA|NA	O	Psort location Cytoplasmic, score 8.96
MAG.T21.18_02121	395494.Galf_1844	5.5e-26	123.6	Bacteria	gldC												Bacteria	2AGY9@1,3176X@2	NA|NA|NA	S	Gliding motility-associated protein GldC
MAG.T21.18_02122	1279009.ADICEAN_01273	4e-57	228.0	Cytophagia	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03978					ko00000,ko03036				Bacteria	47P6H@768503,4NEA9@976,COG0218@1,COG0218@2	NA|NA|NA	D	Necessary for normal cell division and for the maintenance of normal septation
MAG.T21.18_02123	1408813.AYMG01000028_gene2431	2.7e-84	318.5	Sphingobacteriia	ohpC		3.7.1.14	ko:K05714	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R02603,R06789	RC00752,RC00753,RC01337	br01602,ko00000,ko00001,ko00002,ko01000				Bacteria	1INU7@117747,4NF80@976,COG2267@1,COG2267@2	NA|NA|NA	I	Alpha beta hydrolase
MAG.T21.18_02124	867902.Ornrh_0576	1.2e-31	142.9	Flavobacteriia	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141		ko:K03925					ko00000				Bacteria	1I198@117743,4NM4X@976,COG2001@1,COG2001@2	NA|NA|NA	K	Belongs to the MraZ family
MAG.T21.18_02125	714943.Mucpa_1530	2.8e-88	332.0	Sphingobacteriia	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438					ko00000,ko01000,ko03009				Bacteria	1INNA@117747,4NFQB@976,COG0275@1,COG0275@2	NA|NA|NA	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAG.T21.18_02127	929556.Solca_2743	4.5e-161	575.1	Sphingobacteriia	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	2.7.11.1,3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K12132,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01001,ko01011,ko03036			iSSON_1240.SSON_0092	Bacteria	1IQ79@117747,4NERV@976,COG0768@1,COG0768@2,COG2815@1,COG2815@2	NA|NA|NA	M	Cell division protein FtsI penicillin-binding protein 2
MAG.T21.18_02128	1358423.N180_11935	4.5e-160	571.2	Sphingobacteriia	murE		6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550		R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1INW4@117747,4NE9W@976,COG0769@1,COG0769@2	NA|NA|NA	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAG.T21.18_02129	929556.Solca_2741	1.4e-154	552.7	Sphingobacteriia	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502		R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146		iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Bacteria	1IQU9@117747,4NE0T@976,COG0472@1,COG0472@2	NA|NA|NA	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAG.T21.18_02130	143224.JQMD01000002_gene2244	4e-139	501.5	Flavobacteriia	murD		6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100		R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1HX80@117743,4NEFF@976,COG0771@1,COG0771@2	NA|NA|NA	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAG.T21.18_02131	1121468.AUBR01000006_gene362	4.8e-21	107.8	Thermoanaerobacterales	murD		6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100		R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1TQ3P@1239,248GS@186801,42EZQ@68295,COG0771@1,COG0771@2	NA|NA|NA	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAG.T21.18_02132	485918.Cpin_6977	5.2e-85	321.6	Sphingobacteriia	ftsW			ko:K03588	ko04112,map04112				ko00000,ko00001,ko02000,ko03036	2.A.103.1			Bacteria	1IPWG@117747,4NFIM@976,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
MAG.T21.18_02133	1121481.AUAS01000013_gene4160	4.1e-102	378.3	Cytophagia	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112		R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011		GT28	iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Bacteria	47JXF@768503,4NE6D@976,COG0707@1,COG0707@2	NA|NA|NA	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAG.T21.18_02134	393921.HQ45_00810	2.1e-111	409.5	Porphyromonadaceae	murC		6.3.2.4,6.3.2.8	ko:K01921,ko:K01924	ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502		R01150,R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	22WMY@171551,2FM6G@200643,4NE1V@976,COG0773@1,COG0773@2	NA|NA|NA	M	Belongs to the MurCDEF family
MAG.T21.18_02135	1408813.AYMG01000017_gene5511	2.3e-36	159.5	Sphingobacteriia	ftsQ			ko:K03589	ko04112,map04112				ko00000,ko00001,ko03036				Bacteria	1IRV2@117747,4NGPN@976,COG1589@1,COG1589@2	NA|NA|NA	M	Cell division protein
MAG.T21.18_02136	1408433.JHXV01000032_gene1130	2.2e-150	538.9	Cryomorphaceae	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363		ko:K03590	ko04112,map04112				ko00000,ko00001,ko03036,ko04812				Bacteria	1HY6Y@117743,2PA5T@246874,4NE0V@976,COG0849@1,COG0849@2	NA|NA|NA	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAG.T21.18_02137	1408433.JHXV01000032_gene1131	6.6e-136	491.1	Cryomorphaceae	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03531	ko04112,map04112				ko00000,ko00001,ko02048,ko03036,ko04812				Bacteria	1HWTE@117743,2PADU@246874,4NF8N@976,COG0206@1,COG0206@2	NA|NA|NA	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAG.T21.18_02138	700598.Niako_6586	1e-34	153.3	Sphingobacteriia	yqeY			ko:K09117					ko00000				Bacteria	1IT3W@117747,4NQFI@976,COG1610@1,COG1610@2	NA|NA|NA	S	PFAM Yqey-like protein
MAG.T21.18_02139	1408433.JHXV01000024_gene1478	5.1e-69	267.7	Cryomorphaceae													Bacteria	1I1SA@117743,2PBHX@246874,4NM5Q@976,COG0745@1,COG0745@2	NA|NA|NA	T	Transcriptional regulatory protein, C terminal
MAG.T21.18_02140	755732.Fluta_0821	2.1e-95	356.3	Cryomorphaceae													Bacteria	1HZ71@117743,2PBGE@246874,4NEFW@976,COG0642@1,COG2205@2	NA|NA|NA	T	GHKL domain
MAG.T21.18_02141	1313301.AUGC01000010_gene982	7.6e-89	334.7	Bacteroidetes													Bacteria	4NE7V@976,COG1807@1,COG1807@2	NA|NA|NA	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related
MAG.T21.18_02142	1408433.JHXV01000007_gene2924	1.5e-55	223.8	Bacteria			3.2.1.14,3.2.1.40	ko:K01183,ko:K05989	ko00520,ko01100,map00520,map01100		R01206,R02334	RC00467	ko00000,ko00001,ko01000		GH18		Bacteria	COG3325@1,COG3325@2	NA|NA|NA	G	chitin binding
MAG.T21.18_02143	313606.M23134_02318	1.6e-106	392.9	Cytophagia	hmuS			ko:K02016,ko:K07225	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	47MSN@768503,4NEZU@976,COG3720@1,COG3720@2	NA|NA|NA	P	heme degradation protein
MAG.T21.18_02144	1408433.JHXV01000007_gene2926	8.6e-126	458.0	Cryomorphaceae				ko:K16089					ko00000,ko02000	1.B.14.1,1.B.14.10			Bacteria	1HY46@117743,2PAD5@246874,4NET0@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB-dependent Receptor Plug Domain
MAG.T21.18_02145	1408433.JHXV01000007_gene2927	2.3e-56	226.1	Cryomorphaceae													Bacteria	1IHII@117743,2AXDY@1,2PB08@246874,31PDA@2,4PJH6@976	NA|NA|NA	S	HmuY protein
MAG.T21.18_02146	700598.Niako_2068	8.9e-124	451.4	Sphingobacteriia													Bacteria	1IVBF@117747,4NEIG@976,COG1629@1,COG4771@2	NA|NA|NA	P	Outer membrane protein beta-barrel family
MAG.T21.18_02147	1304275.C41B8_18231	3.2e-22	112.1	Gammaproteobacteria	rbpA												Bacteria	1N6VR@1224,1SCKA@1236,COG0724@1,COG0724@2	NA|NA|NA	S	RNA-binding
MAG.T21.18_02148	1304876.AZVC01000017_gene406	3.9e-12	78.2	Actinobacteria													Bacteria	2IKRU@201174,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of hsp90 atpase 1 family protein
MAG.T21.18_02149	1123278.KB893559_gene2996	5.7e-64	251.5	Cytophagia													Bacteria	47JD3@768503,4NETA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_02150	1237149.C900_02500	2.3e-71	275.4	Cytophagia			1.5.1.40	ko:K06988					ko00000,ko01000				Bacteria	47Q30@768503,4NQ1G@976,COG2085@1,COG2085@2	NA|NA|NA	S	NADP oxidoreductase coenzyme F420-dependent
MAG.T21.18_02151	1122225.AULQ01000005_gene2642	2.2e-38	165.2	Flavobacteriia	osmC			ko:K04063					ko00000				Bacteria	1I2YF@117743,4NQKB@976,COG1764@1,COG1764@2	NA|NA|NA	O	Peroxiredoxin
MAG.T21.18_02152	929703.KE386491_gene3153	4.8e-119	434.5	Cytophagia	desD		1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100		R07063	RC00917	ko00000,ko00001,ko01000,ko01004			iJN678.desD_des6_	Bacteria	47NRC@768503,4NERD@976,COG3239@1,COG3239@2	NA|NA|NA	I	fatty acid desaturase
MAG.T21.18_02153	313606.M23134_04088	2.4e-98	366.3	Cytophagia													Bacteria	47MYA@768503,4NGER@976,COG5316@1,COG5316@2	NA|NA|NA	S	N-terminal domain of unknown function (DUF4140)
MAG.T21.18_02156	1144275.COCOR_02798	0.0	2109.0	Proteobacteria	nrsA			ko:K13611,ko:K15661	ko01054,map01054				ko00000,ko00001,ko01004,ko01008				Bacteria	1QK4F@1224,COG0001@1,COG0001@2,COG1020@1,COG1020@2,COG3321@1,COG3321@2	NA|NA|NA	Q	Non-ribosomal peptide synthetase modules and related proteins
MAG.T21.18_02157	1173020.Cha6605_2830	2.9e-294	1018.5	Cyanobacteria			6.3.2.14	ko:K00612,ko:K02364,ko:K04780,ko:K19103	ko00261,ko01053,ko01110,ko01130,map00261,map01053,map01110,map01130	M00736	R07644,R10880	RC00064,RC00141,RC00162,RC03046,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002,ko01000,ko01008				Bacteria	1G0XE@1117,COG1020@1,COG1020@2,COG3319@1,COG3319@2	NA|NA|NA	Q	Amino acid adenylation domain
MAG.T21.18_02158	335659.S23_56370	7.8e-23	114.4	Bradyrhizobiaceae													Bacteria	1R89Z@1224,2UR2U@28211,3JZ58@41294,COG3321@1,COG3321@2	NA|NA|NA	Q	Ketoacyl-synthetase C-terminal extension
MAG.T21.18_02159	1408433.JHXV01000030_gene1396	1.2e-95	356.3	Cryomorphaceae	murQ		4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100		R08555	RC00397,RC00746	ko00000,ko00001,ko01000				Bacteria	1HXU4@117743,2PA99@246874,4NEPY@976,COG2103@1,COG2103@2	NA|NA|NA	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MAG.T21.18_02160	1469557.JSWF01000016_gene2208	1.6e-70	273.9	Flavobacteriia													Bacteria	1HXZZ@117743,2DB82@1,2Z7PX@2,4NEW5@976	NA|NA|NA		
MAG.T21.18_02161	313590.MED134_04364	1.2e-85	323.6	Dokdonia													Bacteria	1HWNH@117743,37DS8@326319,4NEEZ@976,COG1012@1,COG1012@2	NA|NA|NA	C	Acyl-CoA reductase (LuxC)
MAG.T21.18_02162	755732.Fluta_3569	9.3e-48	196.1	Cryomorphaceae	fdx1												Bacteria	1IJ7N@117743,2PAUC@246874,4PKCQ@976,COG1143@1,COG1143@2	NA|NA|NA	C	4Fe-4S binding domain
MAG.T21.18_02163	1150600.ADIARSV_0135	2.5e-36	159.5	Sphingobacteriia													Bacteria	1IRUJ@117747,28P29@1,2ZBYD@2,4NMK6@976	NA|NA|NA		
MAG.T21.18_02164	1121896.JMLU01000031_gene2262	4.7e-130	471.1	Flavobacterium	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1HYNV@117743,2NSH9@237,4NE06@976,COG1932@1,COG1932@2	NA|NA|NA	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MAG.T21.18_02165	1122621.ATZA01000018_gene3894	6.3e-94	350.9	Sphingobacteriia			1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147			iLJ478.TM1401	Bacteria	1INZ9@117747,4PKE3@976,COG1052@1,COG1052@2	NA|NA|NA	CH	D-isomer specific 2-hydroxyacid dehydrogenase
MAG.T21.18_02166	926562.Oweho_1600	1.1e-74	287.3	Cryomorphaceae													Bacteria	1HX17@117743,2PA8E@246874,4NGQH@976,COG4198@1,COG4198@2	NA|NA|NA	S	Protein of unknown function (DUF1015)
MAG.T21.18_02167	925409.KI911562_gene2303	2.7e-54	218.8	Sphingobacteriia	yggS			ko:K06997					ko00000				Bacteria	1INT9@117747,4NE42@976,COG0325@1,COG0325@2	NA|NA|NA	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MAG.T21.18_02168	1313421.JHBV01000022_gene4705	2.6e-13	83.2	Bacteroidetes	rpfI		3.1.3.48	ko:K01104,ko:K21449,ko:K21473					ko00000,ko01000,ko01002,ko01011,ko02000	1.B.40.2			Bacteria	4NRRF@976,COG1196@1,COG1196@2,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_02169	1168034.FH5T_15410	5e-08	64.7	Bacteroidia													Bacteria	2EQMK@1,2FVUP@200643,33I7I@2,4NY3R@976	NA|NA|NA		
MAG.T21.18_02170	929556.Solca_2919	2e-168	599.4	Sphingobacteriia	yfmR			ko:K15738					ko00000,ko02000	3.A.1.120.6			Bacteria	1IPI4@117747,4NES5@976,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
MAG.T21.18_02171	1279009.ADICEAN_03215	2.8e-68	265.8	Cytophagia													Bacteria	47MUX@768503,4NG13@976,COG4772@1,COG4772@2	NA|NA|NA	P	TIGRFAM Bacteroidetes-specific
MAG.T21.18_02172	153721.MYP_3101	5.5e-95	355.1	Cytophagia													Bacteria	47TIX@768503,4P298@976,COG0457@1,COG0457@2,COG0823@1,COG0823@2	NA|NA|NA	U	WD40-like Beta Propeller Repeat
MAG.T21.18_02173	153721.MYP_2331	9.2e-196	691.4	Cytophagia													Bacteria	47P4N@768503,4PHTU@976,COG2755@1,COG2755@2,COG3291@1,COG3291@2	NA|NA|NA	E	Repeats in polycystic kidney disease 1 (PKD1) and other proteins
MAG.T21.18_02174	755732.Fluta_3279	9.8e-163	580.1	Cryomorphaceae	lpdA		1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IGB0@117743,2PBK6@246874,4NJ2P@976,COG1249@1,COG1249@2	NA|NA|NA	C	FAD dependent oxidoreductase
MAG.T21.18_02175	983544.Lacal_1182	7e-89	334.3	Flavobacteriia			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	1HXUF@117743,4NE4P@976,COG1858@1,COG1858@2	NA|NA|NA	C	cytochrome C peroxidase
MAG.T21.18_02176	1519464.HY22_08930	2.6e-76	292.4	Chlorobi			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	1FDVA@1090,COG1858@1,COG1858@2	NA|NA|NA	C	PFAM Di-haem cytochrome c peroxidase
MAG.T21.18_02177	1408433.JHXV01000030_gene1408	2.4e-16	92.8	Cryomorphaceae													Bacteria	1IA62@117743,2DX5Q@1,2PB79@246874,343H0@2,4P5PC@976	NA|NA|NA		
MAG.T21.18_02178	1233950.IW22_18365	1.4e-13	84.3	Bacteroidetes													Bacteria	4PNEQ@976,COG4733@1,COG4733@2	NA|NA|NA	S	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02181	1123057.P872_14365	8.2e-21	108.6	Cytophagia													Bacteria	47XYW@768503,4NIJT@976,COG3386@1,COG3386@2,COG4733@1,COG4733@2	NA|NA|NA	G	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02183	926549.KI421517_gene1100	5.2e-214	750.4	Cytophagia	fumC		4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000				Bacteria	47JKQ@768503,4NEQP@976,COG0114@1,COG0114@2	NA|NA|NA	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MAG.T21.18_02184	443143.GM18_0588	2.2e-12	79.3	Deltaproteobacteria													Bacteria	1NPW3@1224,2ARAZ@1,2WY42@28221,31GKZ@2,43320@68525	NA|NA|NA	S	Domain of unknown function (DUF3332)
MAG.T21.18_02185	1123277.KB893184_gene4186	5.6e-176	624.0	Cytophagia	blh		3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	47KD4@768503,4NE2Y@976,COG0491@1,COG0491@2,COG2897@1,COG2897@2	NA|NA|NA	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase
MAG.T21.18_02186	242619.PG_1572	3e-62	245.4	Bacteroidia				ko:K07090					ko00000				Bacteria	2FVIS@200643,4NFWP@976,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.18_02187	379066.GAU_3018	1.1e-76	293.9	Gemmatimonadetes	rnd		3.1.13.5	ko:K03684					ko00000,ko01000,ko03016				Bacteria	1ZSPS@142182,COG0349@1,COG0349@2	NA|NA|NA	J	3'-5' exonuclease
MAG.T21.18_02188	1197477.IA57_00215	4.4e-19	100.9	Flavobacteriia													Bacteria	1I559@117743,2E37T@1,32Y7G@2,4NUTJ@976	NA|NA|NA	S	Protein of unknown function (DUF2752)
MAG.T21.18_02189	1454007.JAUG01000004_gene2660	9e-17	92.8	Bacteroidetes													Bacteria	2DRED@1,33BD9@2,4PNGN@976	NA|NA|NA	S	Interferon-induced transmembrane protein
MAG.T21.18_02190	391596.PBAL39_01662	1.5e-104	386.3	Sphingobacteriia	manC		2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1IV11@117747,4NE1Y@976,COG0836@1,COG0836@2	NA|NA|NA	M	mannose-1-phosphate guanylyltransferase
MAG.T21.18_02191	700598.Niako_0376	3.4e-34	152.1	Sphingobacteriia	sprT			ko:K02742					ko00000				Bacteria	1IS5M@117747,4NDXX@976,COG3091@1,COG3091@2	NA|NA|NA	S	PFAM SprT-like family
MAG.T21.18_02192	385682.AFSL01000014_gene2722	7.2e-74	283.9	Marinilabiliaceae	mlaE			ko:K02066	ko02010,map02010	M00210,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	2FNVR@200643,3XIZS@558415,4NEZ8@976,COG0767@1,COG0767@2	NA|NA|NA	Q	Permease MlaE
MAG.T21.18_02193	1408433.JHXV01000020_gene3500	2.8e-89	335.1	Cryomorphaceae	mkl			ko:K02065	ko02010,map02010	M00210,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1HXNN@117743,2PAAD@246874,4NETG@976,COG1127@1,COG1127@2	NA|NA|NA	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component
MAG.T21.18_02194	742817.HMPREF9449_01458	3.5e-08	67.0	Porphyromonadaceae													Bacteria	22W8U@171551,2FQU9@200643,4NE1H@976,COG1501@1,COG1501@2	NA|NA|NA	G	Domain of unknown function (DUF5110)
MAG.T21.18_02195	1150864.MILUP08_46540	1.7e-07	64.7	Micromonosporales	nanM	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	5.1.3.24	ko:K13276,ko:K17948					ko00000,ko01000,ko01002,ko03110				Bacteria	2IF2T@201174,4DBYG@85008,COG1404@1,COG1404@2,COG3055@1,COG3055@2	NA|NA|NA	O	Peptidase S8 and S53 subtilisin kexin sedolisin
MAG.T21.18_02196	1122176.KB903551_gene4255	6e-18	99.4	Bacteroidetes				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	4P12F@976,COG3391@1,COG3391@2	NA|NA|NA	E	Zinc metalloprotease (Elastase)
MAG.T21.18_02197	1485544.JQKP01000002_gene1533	0.0	1218.4	Nitrosomonadales	gcvP	GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_3318	Bacteria	1MUDP@1224,2VHQ6@28216,44V7J@713636,COG0403@1,COG0403@2,COG1003@1,COG1003@2	NA|NA|NA	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MAG.T21.18_02199	760192.Halhy_6289	5.4e-15	88.6	Sphingobacteriia	ispH		1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000				Bacteria	1IR8U@117747,4NM5C@976,COG0382@1,COG0382@2	NA|NA|NA	H	PFAM UbiA prenyltransferase family
MAG.T21.18_02200	755732.Fluta_1605	1.9e-143	515.8	Cryomorphaceae	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWY8@117743,2PAF8@246874,4NECS@976,COG3844@1,COG3844@2	NA|NA|NA	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
MAG.T21.18_02201	926562.Oweho_1808	5.5e-144	517.7	Cryomorphaceae	kmo	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXAE@117743,2PA4J@246874,4NGIU@976,COG0654@1,COG0654@2	NA|NA|NA	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid
MAG.T21.18_02203	880073.Calab_0585	2.1e-21	108.6	unclassified Bacteria	vapC												Bacteria	2NS13@2323,COG1487@1,COG1487@2	NA|NA|NA	S	PIN domain
MAG.T21.18_02204	436229.JOEH01000005_gene3132	7e-31	139.8	Streptacidiphilus													Bacteria	29RZY@1,2HRBH@201174,2NN8K@228398,30D49@2	NA|NA|NA		
MAG.T21.18_02205	1408433.JHXV01000011_gene1999	2.2e-18	99.8	Cryomorphaceae													Bacteria	1ICSX@117743,2BV66@1,2PC1F@246874,32QJI@2,4PC9C@976	NA|NA|NA		
MAG.T21.18_02206	1124780.ANNU01000028_gene1013	1.8e-57	229.2	Cytophagia	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	47PA3@768503,4NE2Y@976,COG0491@1,COG0491@2	NA|NA|NA	P	PFAM Metallo-beta-lactamase superfamily
MAG.T21.18_02207	1408433.JHXV01000010_gene496	5.9e-221	774.6	Cryomorphaceae				ko:K07277					ko00000,ko02000,ko03029	1.B.33			Bacteria	1I8E9@117743,2PBCC@246874,4NERT@976,COG4775@1,COG4775@2	NA|NA|NA	M	PFAM WD40-like beta Propeller
MAG.T21.18_02208	1239415.CM001837_gene43	1.6e-29	135.6	Flavobacteriia				ko:K07090					ko00000				Bacteria	1I2UM@117743,4NTZ8@976,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.18_02209	1239962.C943_03726	8.6e-109	400.6	Cytophagia	ammA			ko:K01436					ko00000,ko01000,ko01002				Bacteria	47KGA@768503,4NGBI@976,COG1473@1,COG1473@2	NA|NA|NA	S	PFAM Peptidase family M20 M25 M40
MAG.T21.18_02211	1408433.JHXV01000033_gene1144	2.6e-268	931.4	Cryomorphaceae	recQ		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	1HXCJ@117743,2PABT@246874,4NEB4@976,COG0514@1,COG0514@2	NA|NA|NA	L	RQC
MAG.T21.18_02212	926562.Oweho_3396	2.3e-71	275.8	Cryomorphaceae	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680		ko:K03118	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1HYNB@117743,2PASC@246874,4NEKM@976,COG0805@1,COG0805@2	NA|NA|NA	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MAG.T21.18_02213	153721.MYP_191	3.9e-180	638.6	Cytophagia													Bacteria	47MWA@768503,4NDYT@976,COG4775@1,COG4775@2	NA|NA|NA	M	CarboxypepD_reg-like domain
MAG.T21.18_02214	485918.Cpin_0868	1.7e-99	369.0	Sphingobacteriia	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320			ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1			Bacteria	1IQQ1@117747,4NDUG@976,COG1137@1,COG1137@2	NA|NA|NA	S	ABC transporter
MAG.T21.18_02215	1121011.AUCB01000012_gene1592	6.8e-32	145.2	Arenibacter													Bacteria	1I798@117743,23G7K@178469,2EVZZ@1,33PDF@2,4P17P@976	NA|NA|NA		
MAG.T21.18_02216	1123276.KB893245_gene1480	1.6e-83	316.2	Cytophagia				ko:K06384					ko00000				Bacteria	47MPK@768503,4NG8D@976,COG1300@1,COG1300@2	NA|NA|NA	S	Stage II sporulation protein M
MAG.T21.18_02217	1454007.JAUG01000004_gene2656	3.1e-10	72.8	Bacteroidetes	flhB			ko:K02401,ko:K13820	ko02040,map02040				ko00000,ko00001,ko02035,ko02044	3.A.6.2			Bacteria	4NMN3@976,COG1377@1,COG1377@2	NA|NA|NA	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MAG.T21.18_02218	1270196.JCKI01000001_gene4154	7.2e-23	114.4	Sphingobacteriia													Bacteria	1IT48@117747,29GF6@1,303CZ@2,4NR6I@976	NA|NA|NA	S	Domain of unknown function (DUF4129)
MAG.T21.18_02219	1279009.ADICEAN_02370	1.1e-50	207.6	Cytophagia													Bacteria	28IVH@1,2Z8TX@2,47N52@768503,4NEEW@976	NA|NA|NA		
MAG.T21.18_02220	1519464.HY22_14140	6.5e-107	394.0	Chlorobi	moxR2			ko:K03924					ko00000,ko01000				Bacteria	1FDTI@1090,COG0714@1,COG0714@2	NA|NA|NA	S	PFAM ATPase associated with various cellular activities, AAA_3
MAG.T21.18_02221	504472.Slin_4966	1e-118	433.7	Cytophagia													Bacteria	47JBI@768503,4NE10@976,COG1721@1,COG1721@2	NA|NA|NA	S	Protein of unknown function DUF58
MAG.T21.18_02222	1089547.KB913013_gene711	1e-21	109.8	Cytophagia	XK27_07670			ko:K07397					ko00000				Bacteria	47QVZ@768503,4NFWN@976,COG1765@1,COG1765@2	NA|NA|NA	O	OsmC-like protein
MAG.T21.18_02223	1121904.ARBP01000012_gene1285	5.3e-40	170.6	Cytophagia	yjdI		1.6.3.4	ko:K07397,ko:K22405					ko00000,ko01000				Bacteria	47QRI@768503,4NVG3@976,COG3369@1,COG3369@2,COG3592@1,COG3592@2	NA|NA|NA	S	Divergent 4Fe-4S mono-cluster
MAG.T21.18_02224	1453500.AT05_09780	4.6e-173	614.4	Flavobacteriia	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1HWWY@117743,4NEIR@976,COG1057@1,COG1057@2	NA|NA|NA	H	Nicotinate-nucleotide adenylyltransferase
MAG.T21.18_02225	1121129.KB903359_gene1105	1.8e-61	244.2	Porphyromonadaceae													Bacteria	22ZIC@171551,2DBB3@1,2FPU7@200643,2Z85F@2,4NKCY@976	NA|NA|NA	S	Domain of unknown function (4846)
MAG.T21.18_02226	1449353.JQMQ01000005_gene3952	1.1e-14	87.4	Actinobacteria	MA20_41110		2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000				Bacteria	2IF74@201174,COG0223@1,COG0223@2	NA|NA|NA	J	Formyl transferase
MAG.T21.18_02227	1122179.KB890432_gene4138	2.7e-22	112.8	Sphingobacteriia			2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	1J18Y@117747,4NKC3@976,COG2319@1,COG2319@2	NA|NA|NA	C	WD domain, G-beta repeat
MAG.T21.18_02228	1121898.Q766_08580	4.7e-97	361.3	Flavobacterium	wbpP		5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWQR@117743,2NSY4@237,4NEKA@976,COG0451@1,COG0451@2	NA|NA|NA	GM	Vi polysaccharide biosynthesis protein VipB TviC
MAG.T21.18_02229	755732.Fluta_3824	2.6e-41	175.6	Bacteroidetes	cheW-3		2.1.1.80,3.1.1.61	ko:K00575,ko:K03408,ko:K13924	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko01000,ko02022,ko02035				Bacteria	4P3Q6@976,COG1352@1,COG1352@2	NA|NA|NA	NT	Methyltransferase domain
MAG.T21.18_02230	755732.Fluta_2173	1.7e-181	642.5	Cryomorphaceae	rny			ko:K18682	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1HYHI@117743,2PA4M@246874,4NE3V@976,COG1418@1,COG1418@2	NA|NA|NA	S	Domain of unknown function (DUF3552)
MAG.T21.18_02231	1408433.JHXV01000024_gene1483	1.2e-08	65.9	Cryomorphaceae	zapA	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047		ko:K09888					ko00000,ko03036				Bacteria	1I41M@117743,2PB8C@246874,4NSA5@976,COG3027@1,COG3027@2	NA|NA|NA	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MAG.T21.18_02233	1168034.FH5T_20305	2.8e-92	346.3	Bacteroidia													Bacteria	2FP3N@200643,4NED7@976,COG0739@1,COG0739@2	NA|NA|NA	M	Peptidase, M23 family
MAG.T21.18_02234	880071.Fleli_2836	9.7e-17	94.0	Cytophagia			3.1.4.46	ko:K01126	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	47S2Q@768503,4NUR0@976,COG0584@1,COG0584@2	NA|NA|NA	C	Glycerophosphoryl diester phosphodiesterase family
MAG.T21.18_02235	755732.Fluta_2064	5.6e-73	282.0	Bacteria			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_02236	1089547.KB913013_gene876	6.5e-62	244.2	Cytophagia				ko:K13002					ko00000,ko01000,ko01003,ko01005		GT2		Bacteria	47N3D@768503,4NGHQ@976,COG1216@1,COG1216@2	NA|NA|NA	S	PFAM Glycosyl transferase family 2
MAG.T21.18_02238	1123234.AUKI01000014_gene2448	8.9e-56	223.4	Flavobacteriia	wcaF		2.3.1.79	ko:K00661,ko:K03818					ko00000,ko01000				Bacteria	1I1H0@117743,4NMZ2@976,COG0110@1,COG0110@2	NA|NA|NA	S	acetyltransferase, isoleucine patch superfamily
MAG.T21.18_02239	1168289.AJKI01000012_gene322	1.7e-74	286.6	Marinilabiliaceae													Bacteria	2FTK8@200643,3XK9W@558415,4NMHA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_02240	385682.AFSL01000001_gene1997	1.8e-76	293.1	Marinilabiliaceae													Bacteria	2FTR3@200643,3XK2C@558415,4NJ1W@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_02241	42256.RradSPS_2615	1e-37	163.7	Actinobacteria													Bacteria	2DBUE@1,2H9SV@201174,2ZB5Q@2	NA|NA|NA		
MAG.T21.18_02242	515635.Dtur_1285	2.3e-27	130.2	Bacteria													Bacteria	COG1404@1,COG1404@2,COG1520@1,COG1520@2	NA|NA|NA	S	amino acid activation for nonribosomal peptide biosynthetic process
MAG.T21.18_02243	269798.CHU_0078	2.6e-33	150.2	Bacteria													Bacteria	COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase activity
MAG.T21.18_02244	1168034.FH5T_16820	1.1e-95	357.1	Bacteroidia				ko:K07098					ko00000				Bacteria	2FP07@200643,4NFCH@976,COG1408@1,COG1408@2	NA|NA|NA	S	Ser Thr phosphatase family protein
MAG.T21.18_02245	903818.KI912268_gene3202	9.1e-33	146.4	Acidobacteria				ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	3Y8G5@57723,COG0614@1,COG0614@2	NA|NA|NA	P	PD-(D/E)XK nuclease superfamily
MAG.T21.18_02246	926562.Oweho_0693	4.9e-90	337.8	Cryomorphaceae	mvaB		4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWWP@117743,2PA7K@246874,4NDZH@976,COG0119@1,COG0119@2	NA|NA|NA	E	HMGL-like
MAG.T21.18_02247	1120968.AUBX01000011_gene3082	1.5e-101	376.3	Cytophagia	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000			iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	Bacteria	47KYQ@768503,4NDVB@976,COG0167@1,COG0167@2	NA|NA|NA	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MAG.T21.18_02248	886379.AEWI01000137_gene2260	9.1e-260	902.9	Marinilabiliaceae	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03702	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2FNBD@200643,3XJ69@558415,4NE6E@976,COG0556@1,COG0556@2	NA|NA|NA	L	Ultra-violet resistance protein B
MAG.T21.18_02249	1317122.ATO12_05430	1e-106	394.0	Aquimarina			3.4.21.107,3.4.21.50	ko:K01337,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1I89F@117743,2YGTW@290174,4PKT1@976,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like peptidase domain
MAG.T21.18_02250	755732.Fluta_1637	3.9e-118	431.8	Cryomorphaceae	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464											Bacteria	1HXPY@117743,2PA4Y@246874,4NENX@976,COG1774@1,COG1774@2	NA|NA|NA	S	PSP1 C-terminal conserved region
MAG.T21.18_02251	1168034.FH5T_08795	5.1e-28	131.0	Bacteroidia	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575											Bacteria	2ADSH@1,2FUJF@200643,313I2@2,4NQMU@976	NA|NA|NA	S	Gliding motility-associated lipoprotein, GldH
MAG.T21.18_02252	926562.Oweho_2448	1.9e-203	716.1	Cryomorphaceae	mrcA		2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1HXWX@117743,2PAGV@246874,4NECJ@976,COG5009@1,COG5009@2	NA|NA|NA	M	PFAM Penicillin binding protein transpeptidase domain
MAG.T21.18_02254	1123236.KB899393_gene3203	4.1e-11	76.3	Alteromonadaceae													Bacteria	1RIG3@1224,1S8BF@1236,4686A@72275,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_02255	1111730.ATTM01000004_gene2081	5.8e-34	152.5	Flavobacterium	pdtaS		2.7.13.3	ko:K00936		M00839			ko00000,ko00002,ko01000,ko01001,ko02022				Bacteria	1HWYS@117743,2NVMV@237,4NINT@976,COG0457@1,COG0457@2,COG3920@1,COG3920@2	NA|NA|NA	T	Histidine kinase
MAG.T21.18_02257	1089547.KB913013_gene3412	1.2e-103	383.3	Cytophagia	ltaA		4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230		R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000				Bacteria	47KXF@768503,4NEIH@976,COG2008@1,COG2008@2	NA|NA|NA	E	Threonine aldolase
MAG.T21.18_02258	1250278.JQNQ01000001_gene3341	1.2e-16	92.8	Flavobacteriia													Bacteria	1I3WS@117743,2CYW5@1,32T50@2,4NS73@976	NA|NA|NA		
MAG.T21.18_02259	888059.HMPREF9071_0418	1.1e-59	236.5	Capnocytophaga	yrrM		2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000				Bacteria	1EQX4@1016,1HYQJ@117743,4NH42@976,COG4122@1,COG4122@2	NA|NA|NA	S	O-methyltransferase
MAG.T21.18_02261	485917.Phep_3722	1.6e-231	808.9	Sphingobacteriia	fadE		1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212		R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000				Bacteria	1IPBZ@117747,4NG2G@976,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
MAG.T21.18_02262	1185876.BN8_02027	1.5e-17	97.4	Cytophagia													Bacteria	47KG1@768503,4NI2T@976,COG3292@1,COG3292@2	NA|NA|NA	T	PFAM Two component regulator propeller
MAG.T21.18_02264	1163408.UU9_09042	4.9e-114	417.5	Proteobacteria													Bacteria	1QG74@1224,COG5380@1,COG5380@2	NA|NA|NA	O	BRO family, N-terminal domain
MAG.T21.18_02266	755732.Fluta_2447	1.7e-173	615.5	Cryomorphaceae	fadA		2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWRC@117743,2PAEC@246874,4NE3Q@976,COG0183@1,COG0183@2	NA|NA|NA	I	Thiolase, C-terminal domain
MAG.T21.18_02267	478741.JAFS01000001_gene1614	3.4e-160	571.6	Bacteria													Bacteria	COG0827@1,COG0827@2	NA|NA|NA	L	DNA restriction-modification system
MAG.T21.18_02268	1469607.KK073768_gene590	2.3e-73	282.0	Nostocales													Bacteria	1G1A3@1117,1HM3Y@1161,COG0827@1,COG0827@2	NA|NA|NA	L	restriction enzyme NspV
MAG.T21.18_02270	1408433.JHXV01000009_gene1331	1.9e-301	1041.6	Cryomorphaceae	fadB		1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000			iYO844.BSU32840	Bacteria	1HY3C@117743,2PA69@246874,4NF9D@976,COG1024@1,COG1024@2,COG1250@1,COG1250@2	NA|NA|NA	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
MAG.T21.18_02271	1094466.KQS_04025	1.7e-30	139.0	Flavobacterium	marR												Bacteria	1I24N@117743,2NVXD@237,4NNK7@976,COG1846@1,COG1846@2	NA|NA|NA	K	MarR family transcriptional regulator
MAG.T21.18_02272	929556.Solca_3861	7.8e-78	297.4	Sphingobacteriia													Bacteria	1IVBS@117747,28IZ7@1,2Z8WQ@2,4NIAK@976	NA|NA|NA		
MAG.T21.18_02273	1235797.C816_02683	2.9e-27	129.4	Clostridia													Bacteria	1TR5U@1239,248GW@186801,COG2273@1,COG2273@2	NA|NA|NA	G	family 16
MAG.T21.18_02275	1279009.ADICEAN_01286	2.7e-11	75.5	Cytophagia													Bacteria	2AAU0@1,3106Q@2,47Q0I@768503,4NNSV@976	NA|NA|NA		
MAG.T21.18_02276	755732.Fluta_3616	1e-112	413.7	Cryomorphaceae	sdh		1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWVY@117743,2PAAA@246874,4NF46@976,COG0686@1,COG0686@2	NA|NA|NA	C	PFAM Alanine dehydrogenase PNT, C-terminal domain
MAG.T21.18_02279	1120965.AUBV01000003_gene587	7e-24	117.5	Cytophagia													Bacteria	28NMY@1,2ZBNE@2,47PGY@768503,4NN50@976	NA|NA|NA		
MAG.T21.18_02280	1123234.AUKI01000002_gene1793	1.2e-103	383.6	Flavobacteriia	dinF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	1HYBI@117743,4NG7Q@976,COG0534@1,COG0534@2	NA|NA|NA	V	Na -driven multidrug efflux pump
MAG.T21.18_02281	203275.BFO_3098	3.7e-26	126.3	Porphyromonadaceae				ko:K05286	ko00563,ko01100,map00563,map01100	M00065	R05922		ko00000,ko00001,ko00002,ko01000,ko01003		GT22		Bacteria	22ZCU@171551,2FV7D@200643,4NPIJ@976,COG1807@1,COG1807@2	NA|NA|NA	M	Alg9-like mannosyltransferase family
MAG.T21.18_02282	929703.KE386491_gene4134	2.8e-19	102.4	Bacteroidetes													Bacteria	4PKHZ@976,COG0823@1,COG0823@2,COG5384@1,COG5384@2	NA|NA|NA	J	InterPro IPR003367
MAG.T21.18_02284	927658.AJUM01000047_gene2949	1.8e-46	191.8	Marinilabiliaceae	icd		1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	2FQZ2@200643,3XJJG@558415,4NDY2@976,COG0538@1,COG0538@2	NA|NA|NA	C	Isocitrate/isopropylmalate dehydrogenase
MAG.T21.18_02286	929556.Solca_3252	3.5e-94	351.7	Sphingobacteriia	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IPMW@117747,4NHEX@976,COG0416@1,COG0416@2	NA|NA|NA	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MAG.T21.18_02287	485918.Cpin_6298	6.9e-13	79.3	Sphingobacteriia	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904		ko:K02911	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1IU0H@117747,4NUXU@976,COG0333@1,COG0333@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL32 family
MAG.T21.18_02288	927658.AJUM01000037_gene1839	3.9e-26	124.8	Marinilabiliaceae	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464		ko:K07040					ko00000				Bacteria	2FPCJ@200643,3XK60@558415,4NMQT@976,COG1399@1,COG1399@2	NA|NA|NA	S	Uncharacterized ACR, COG1399
MAG.T21.18_02289	794903.OPIT5_11735	1.9e-53	216.1	Opitutae													Bacteria	3K8BC@414999,46V7N@74201,COG0500@1,COG0500@2	NA|NA|NA	Q	methyltransferase
MAG.T21.18_02290	755732.Fluta_1910	4e-153	548.1	Cryomorphaceae	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147			iAF987.Gmet_0122	Bacteria	1HX84@117743,2PAH6@246874,4NEEU@976,COG0469@1,COG0469@2	NA|NA|NA	G	Belongs to the pyruvate kinase family
MAG.T21.18_02292	649349.Lbys_2367	1.9e-34	152.9	Cytophagia	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205				ko00000,ko00001,ko01000,ko03009,ko03019,ko03036				Bacteria	47K17@768503,4NE0N@976,COG0571@1,COG0571@2	NA|NA|NA	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAG.T21.18_02293	761193.Runsl_0725	8.8e-181	639.8	Cytophagia	fabF		2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004			iSB619.SA_RS04785	Bacteria	47MQI@768503,4NEKC@976,COG0304@1,COG0304@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MAG.T21.18_02294	755732.Fluta_1898	2.1e-27	127.9	Cryomorphaceae	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509		ko:K02078					ko00000,ko00001				Bacteria	1I3VI@117743,2PB4S@246874,4NS6C@976,COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAG.T21.18_02295	760192.Halhy_2296	2.1e-72	278.9	Sphingobacteriia													Bacteria	1IUKS@117747,4NFJK@976,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase family
MAG.T21.18_02296	1124780.ANNU01000005_gene2409	5.7e-55	220.7	Cytophagia	purN		2.1.2.2,6.3.2.6,6.3.4.13	ko:K11175,ko:K13713	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04144,R04325,R04326,R04591	RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000				Bacteria	47KTP@768503,4NNZP@976,COG0299@1,COG0299@2	NA|NA|NA	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAG.T21.18_02297	313595.P700755_002041	3.5e-50	204.9	Psychroflexus	marC			ko:K05595					ko00000,ko02000	2.A.95.1			Bacteria	1HXJM@117743,4C2N3@83612,4NG94@976,COG2095@1,COG2095@2	NA|NA|NA	U	MarC family integral membrane protein
MAG.T21.18_02298	1121889.AUDM01000005_gene1678	1.3e-52	212.6	Flavobacterium	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1I1AV@117743,2NSXK@237,4NNQX@976,COG0328@1,COG0328@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAG.T21.18_02299	1048983.EL17_05130	1.7e-26	125.9	Cytophagia	pccA		6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	47QC5@768503,4NQ86@976,COG4770@1,COG4770@2	NA|NA|NA	I	Acetyl propionyl-CoA carboxylase alpha subunit
MAG.T21.18_02300	509635.N824_28385	2.7e-73	282.0	Sphingobacteriia	sodA		1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016				ko00000,ko00001,ko01000				Bacteria	1IRYF@117747,4NK61@976,COG0605@1,COG0605@2	NA|NA|NA	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MAG.T21.18_02301	700598.Niako_6051	2.5e-111	408.7	Sphingobacteriia	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100		R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000			iAF987.Gmet_2683	Bacteria	1INMS@117747,4NFJ9@976,COG0524@1,COG0524@2	NA|NA|NA	G	PFAM pfkB family carbohydrate kinase
MAG.T21.18_02303	1296415.JACC01000030_gene2775	3.2e-72	280.0	Flavobacteriia													Bacteria	1I04H@117743,4NHBK@976,COG2982@1,COG2982@2	NA|NA|NA	M	Domain of Unknown Function (DUF748)
MAG.T21.18_02304	926562.Oweho_0234	7.8e-34	149.8	Cryomorphaceae	ssb			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1I2UG@117743,2PB27@246874,4NQBK@976,COG0629@1,COG0629@2	NA|NA|NA	L	TIGRFAM single stranded DNA-binding protein (ssb)
MAG.T21.18_02305	760192.Halhy_1685	3.7e-48	198.4	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1ISH7@117747,4NQCH@976,COG1595@1,COG1595@2	NA|NA|NA	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MAG.T21.18_02307	926562.Oweho_1402	6.6e-16	92.0	Cryomorphaceae													Bacteria	1IE9N@117743,2PB1T@246874,4PKTY@976,COG3291@1,COG3291@2	NA|NA|NA	J	ASPIC and UnbV
MAG.T21.18_02308	755732.Fluta_0803	1e-25	122.9	Cryomorphaceae	ssb			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1I2UG@117743,2PB27@246874,4NQBK@976,COG0629@1,COG0629@2	NA|NA|NA	L	TIGRFAM single stranded DNA-binding protein (ssb)
MAG.T21.18_02309	755732.Fluta_1556	9.8e-67	260.4	Cryomorphaceae													Bacteria	1IMR1@117743,2PBIA@246874,4NWVX@976,COG0589@1,COG0589@2	NA|NA|NA	T	Universal stress protein family
MAG.T21.18_02310	1408433.JHXV01000015_gene1734	3.4e-133	482.3	Bacteroidetes	srrB			ko:K20971	ko02025,map02025				ko00000,ko00001,ko01001,ko02022				Bacteria	4P03T@976,COG2203@1,COG2203@2,COG2208@1,COG2208@2	NA|NA|NA	T	Sigma factor PP2C-like phosphatases
MAG.T21.18_02311	435591.BDI_1091	2.6e-09	69.7	Porphyromonadaceae													Bacteria	22WMV@171551,2FP2Z@200643,4NIY9@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat protein
MAG.T21.18_02312	1408433.JHXV01000015_gene1736	2e-21	109.4	Bacteroidetes													Bacteria	4NX2D@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.18_02313	761193.Runsl_1462	5.8e-106	391.3	Cytophagia													Bacteria	47NBF@768503,4NE66@976,COG2234@1,COG2234@2	NA|NA|NA	S	PFAM peptidase M28
MAG.T21.18_02314	755732.Fluta_1554	1.9e-57	228.8	Cryomorphaceae	ftnA		1.16.3.2	ko:K02217					ko00000,ko01000				Bacteria	1HY16@117743,2PAVC@246874,4NGS7@976,COG1528@1,COG1528@2	NA|NA|NA	C	Ferritin-like domain
MAG.T21.18_02315	1033732.CAHI01000030_gene1261	3e-64	251.5	Rikenellaceae	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056					ko00000,ko01000,ko03012				Bacteria	22UDM@171550,2FN36@200643,4NI7N@976,COG0193@1,COG0193@2	NA|NA|NA	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAG.T21.18_02316	1349785.BAUG01000043_gene2231	3.5e-40	171.8	Flavobacteriia	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02897	ko03010,map03010	M00178			ko00000,ko00001,ko00002,ko03011				Bacteria	1HWZN@117743,4NEN6@976,COG1825@1,COG1825@2	NA|NA|NA	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MAG.T21.18_02317	1408433.JHXV01000006_gene2780	2e-116	425.6	Cryomorphaceae	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000			iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Bacteria	1HXYP@117743,2PA7D@246874,4NEVF@976,COG0462@1,COG0462@2	NA|NA|NA	EF	Phosphoribosyl synthetase-associated domain
MAG.T21.18_02318	153721.MYP_4904	2.2e-13	84.0	Cytophagia													Bacteria	47XYW@768503,4NIJT@976,COG4733@1,COG4733@2	NA|NA|NA	G	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02319	1313421.JHBV01000009_gene4138	1e-21	112.8	Bacteroidetes			3.4.24.3	ko:K01387					ko00000,ko01000,ko01002,ko02042				Bacteria	4PMDA@976,COG3291@1,COG3291@2	NA|NA|NA	O	domain protein
MAG.T21.18_02322	653733.Selin_1812	1.7e-67	263.1	Bacteria	ppx		3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	COG0248@1,COG0248@2	NA|NA|NA	FP	Ppx GppA phosphatase
MAG.T21.18_02323	1416760.AYMS01000040_gene818	9e-204	716.5	Flavobacteriia	ydaH			ko:K12942					ko00000				Bacteria	1I0S9@117743,4NH64@976,COG2978@1,COG2978@2	NA|NA|NA	H	AbgT putative transporter family
MAG.T21.18_02324	1124780.ANNU01000024_gene3108	0.0	1143.6	Cytophagia	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iLJ478.TM1817	Bacteria	47JHX@768503,4NETB@976,COG0525@1,COG0525@2	NA|NA|NA	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAG.T21.18_02325	1408433.JHXV01000033_gene1145	3.5e-34	151.4	Cryomorphaceae													Bacteria	1I375@117743,2CG1Y@1,2PAZS@246874,31NHZ@2,4NQ9Z@976	NA|NA|NA	S	Protein of unknown function (DUF1573)
MAG.T21.18_02326	1408433.JHXV01000033_gene1145	2e-36	158.7	Cryomorphaceae													Bacteria	1I375@117743,2CG1Y@1,2PAZS@246874,31NHZ@2,4NQ9Z@976	NA|NA|NA	S	Protein of unknown function (DUF1573)
MAG.T21.18_02327	1408433.JHXV01000005_gene2337	3.3e-153	548.1	Cryomorphaceae	aspC		2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007			iHN637.CLJU_RS10450	Bacteria	1HY78@117743,2PAA3@246874,4NG6G@976,COG0436@1,COG0436@2	NA|NA|NA	E	PFAM Aminotransferase class I and II
MAG.T21.18_02329	1313421.JHBV01000029_gene1879	2.2e-52	214.5	Bacteria													Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.18_02331	1408433.JHXV01000002_gene334	4.7e-36	159.8	Bacteria													Bacteria	COG2374@1,COG2374@2,COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_02333	1408433.JHXV01000002_gene334	1.3e-41	179.1	Bacteria													Bacteria	COG2374@1,COG2374@2,COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_02335	1408433.JHXV01000002_gene334	2.8e-39	171.0	Bacteria													Bacteria	COG2374@1,COG2374@2,COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_02336	1408433.JHXV01000002_gene418	3e-15	88.6	Cryomorphaceae													Bacteria	1ICT4@117743,2A9C2@1,2PC2E@246874,30YH0@2,4PCAK@976	NA|NA|NA		
MAG.T21.18_02337	1089550.ATTH01000001_gene2550	7.2e-77	294.3	Bacteroidetes Order II. Incertae sedis	argK	GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111		ko:K07588					ko00000,ko01000				Bacteria	1FJSJ@1100069,4NE7Y@976,COG1703@1,COG1703@2	NA|NA|NA	E	ArgK protein
MAG.T21.18_02338	926549.KI421517_gene1620	2.6e-25	122.1	Cytophagia													Bacteria	28NWP@1,2ZBUH@2,47M02@768503,4NNPT@976	NA|NA|NA		
MAG.T21.18_02339	1406840.Q763_13335	1.1e-119	436.8	Flavobacterium	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007			iHN637.CLJU_RS06550	Bacteria	1HYA7@117743,2NSGC@237,4NENS@976,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
MAG.T21.18_02340	1279009.ADICEAN_01994	1.2e-84	320.1	Cytophagia	rfaE		2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	47K45@768503,4NHUV@976,COG2870@1,COG2870@2	NA|NA|NA	M	pfkB family carbohydrate kinase
MAG.T21.18_02341	518766.Rmar_2332	5.4e-66	257.7	Bacteroidetes Order II. Incertae sedis	menG		2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000				Bacteria	1FJ8B@1100069,4NEDR@976,COG0500@1,COG2226@2	NA|NA|NA	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MAG.T21.18_02342	1408433.JHXV01000017_gene1597	2.6e-36	159.1	Cryomorphaceae													Bacteria	1IE9T@117743,2C52N@1,2PB34@246874,315JU@2,4PJRQ@976	NA|NA|NA	S	Outer membrane protein beta-barrel domain
MAG.T21.18_02343	1296416.JACB01000019_gene4908	9.6e-164	583.6	Aquimarina	IV02_08645			ko:K07137					ko00000				Bacteria	1HXK1@117743,2YI9A@290174,4NEUQ@976,COG2509@1,COG2509@2	NA|NA|NA	S	FAD binding domain
MAG.T21.18_02344	1117315.AHCA01000003_gene206	1.8e-35	156.4	Pseudoalteromonadaceae	spoU		2.1.1.170,2.1.1.185	ko:K03218,ko:K03437,ko:K03501					ko00000,ko01000,ko03009,ko03016,ko03036				Bacteria	1R9JA@1224,1RY04@1236,2Q18N@267888,COG0566@1,COG0566@2	NA|NA|NA	J	RNA methyltransferase, TrmH family
MAG.T21.18_02345	886379.AEWI01000146_gene3235	2.1e-109	403.7	Marinilabiliaceae				ko:K07277					ko00000,ko02000,ko03029	1.B.33			Bacteria	2FM1J@200643,3XJIH@558415,4NE80@976,COG4775@1,COG4775@2	NA|NA|NA	M	Surface antigen
MAG.T21.18_02346	926562.Oweho_1514	8.4e-156	556.6	Cryomorphaceae	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000			iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	Bacteria	1HZ0Q@117743,2PBE4@246874,4NEUM@976,COG1830@1,COG1830@2	NA|NA|NA	G	DeoC/LacD family aldolase
MAG.T21.18_02347	743722.Sph21_1608	7.2e-192	676.8	Sphingobacteriia	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.99.16,2.7.7.7	ko:K02343,ko:K02519,ko:K07114,ko:K16147	ko00230,ko00240,ko00500,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map00500,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378,R09994	RC02795	ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400	1.A.13.2.2,1.A.13.2.3	GH13		Bacteria	1IQ0V@117747,4NGP3@976,COG0532@1,COG0532@2,COG3115@1,COG3115@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAG.T21.18_02348	1408473.JHXO01000001_gene2450	7.2e-13	80.9	Bacteroidia													Bacteria	2EJD3@1,2FVDP@200643,33D44@2,4NYG1@976	NA|NA|NA		
MAG.T21.18_02349	1408433.JHXV01000014_gene3650	7.3e-85	321.2	Cryomorphaceae				ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6			Bacteria	1I8RP@117743,2PAPE@246874,4PKQA@976,COG3474@1,COG3474@2	NA|NA|NA	C	PFAM Class III cytochrome C family
MAG.T21.18_02350	1408433.JHXV01000014_gene3651	4.3e-304	1050.8	Cryomorphaceae	actB			ko:K00184					ko00000	5.A.3			Bacteria	1HWY0@117743,2PA5H@246874,4NE5M@976,COG0437@1,COG0437@2	NA|NA|NA	C	4Fe-4S dicluster domain
MAG.T21.18_02351	755732.Fluta_1182	8.1e-220	769.6	Cryomorphaceae	actC			ko:K00185					ko00000	5.A.3			Bacteria	1HY9P@117743,2PABZ@246874,4NE3X@976,COG5557@1,COG5557@2	NA|NA|NA	C	Polysulphide reductase, NrfD
MAG.T21.18_02352	755732.Fluta_1181	5.2e-66	257.3	Cryomorphaceae	actD												Bacteria	1HXN6@117743,2PAX8@246874,4NEX9@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF3341)
MAG.T21.18_02353	1408433.JHXV01000014_gene3654	1.8e-36	159.5	Cryomorphaceae				ko:K17230	ko00920,ko01120,map00920,map01120		R09499		ko00000,ko00001				Bacteria	1IG0F@117743,2PB3U@246874,4NKQI@976,COG2010@1,COG2010@2,COG2885@1,COG2885@2	NA|NA|NA	C	Cytochrome C oxidase, cbb3-type, subunit III
MAG.T21.18_02354	755732.Fluta_1179	1.6e-115	422.9	Cryomorphaceae	actF												Bacteria	1HY1X@117743,2PAAV@246874,4NF0R@976,COG4531@1,COG4531@2	NA|NA|NA	P	Quinol cytochrome c oxidoreductase
MAG.T21.18_02355	1408433.JHXV01000014_gene3656	1.8e-85	323.2	Cryomorphaceae	coxM	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6			Bacteria	1HWR6@117743,2PATF@246874,4NFNF@976,COG1622@1,COG1622@2	NA|NA|NA	C	Cytochrome C oxidase subunit II, transmembrane domain
MAG.T21.18_02356	755732.Fluta_1177	4.1e-272	943.7	Cryomorphaceae	coxN		1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6			Bacteria	1HXYZ@117743,2PAMC@246874,4NEH8@976,COG0843@1,COG0843@2	NA|NA|NA	C	PFAM Cytochrome C and Quinol oxidase polypeptide I
MAG.T21.18_02357	1041826.FCOL_09370	1.2e-13	83.6	Flavobacterium													Bacteria	1IDQF@117743,2AD0U@1,2NYYD@237,312NT@2,4PHMV@976	NA|NA|NA		
MAG.T21.18_02358	537011.PREVCOP_06257	5.8e-138	497.3	Bacteroidia	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2FNZB@200643,4NEB9@976,COG2255@1,COG2255@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAG.T21.18_02359	487796.Flav2ADRAFT_1015	1.8e-114	419.1	Flavobacteriia	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979					ko00000,ko01000,ko03016				Bacteria	1HWPH@117743,4NFCJ@976,COG1600@1,COG1600@2	NA|NA|NA	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MAG.T21.18_02361	1453500.AT05_05495	1.1e-33	150.6	Bacteroidetes													Bacteria	2DMY7@1,32UCK@2,4NSK3@976	NA|NA|NA	S	Outer membrane protein Omp28
MAG.T21.18_02362	1453500.AT05_00420	1.4e-125	456.8	Flavobacteriia													Bacteria	1HYX2@117743,2CIBF@1,2Z85N@2,4NF0J@976	NA|NA|NA		
MAG.T21.18_02363	926562.Oweho_1917	3.2e-49	201.4	Cryomorphaceae													Bacteria	1I33N@117743,2PAUY@246874,4NNHX@976,COG0526@1,COG0526@2	NA|NA|NA	CO	AhpC TSA family
MAG.T21.18_02364	755732.Fluta_1833	1.7e-58	233.8	Bacteria			1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0526@1,COG0526@2	NA|NA|NA	CO	cell redox homeostasis
MAG.T21.18_02366	84531.JMTZ01000030_gene164	1.6e-67	262.7	Xanthomonadales	cobB			ko:K12410					ko00000,ko01000				Bacteria	1MUK1@1224,1RMX5@1236,1X6B2@135614,COG0846@1,COG0846@2	NA|NA|NA	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MAG.T21.18_02367	760192.Halhy_1987	2.1e-26	125.9	Sphingobacteriia	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IQBR@117747,4NF4E@976,COG0632@1,COG0632@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAG.T21.18_02368	1408433.JHXV01000014_gene3668	0.0	2070.8	Cryomorphaceae	greA												Bacteria	1HXVQ@117743,2PA61@246874,4NEB8@976,COG1747@1,COG1747@2	NA|NA|NA	S	Motility related/secretion protein
MAG.T21.18_02369	313596.RB2501_03610	2.8e-45	188.0	Flavobacteriia	gcvH			ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002				Bacteria	1I1X5@117743,4NQ35@976,COG0509@1,COG0509@2	NA|NA|NA	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MAG.T21.18_02370	1356852.N008_10550	1e-13	83.2	Bacteria	fjo27												Bacteria	COG5652@1,COG5652@2	NA|NA|NA		
MAG.T21.18_02371	866536.Belba_0118	8.3e-37	160.6	Cytophagia	tonB			ko:K03832					ko00000,ko02000	2.C.1.1			Bacteria	47KAX@768503,4NMG7@976,COG0810@1,COG0810@2	NA|NA|NA	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.18_02372	1237149.C900_03118	9.6e-141	506.5	Cytophagia	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000				Bacteria	47KGK@768503,4NETI@976,COG2895@1,COG2895@2	NA|NA|NA	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
MAG.T21.18_02373	1408473.JHXO01000001_gene2242	1.4e-42	180.3	Bacteroidia	gldM												Bacteria	2G096@200643,4PKZS@976,COG4219@1,COG4219@2	NA|NA|NA	KT	Gliding motility-associated protein GldM
MAG.T21.18_02374	1408433.JHXV01000024_gene1509	2.7e-64	252.3	Cryomorphaceae	gldN												Bacteria	1HX8Y@117743,28H74@1,2PAWJ@246874,2Z7JF@2,4NFR0@976	NA|NA|NA	S	TIGRFAM gliding motility associated protien GldN
MAG.T21.18_02375	886379.AEWI01000013_gene2187	1.4e-148	533.5	Marinilabiliaceae				ko:K06158					ko00000,ko03012				Bacteria	2FMY5@200643,3XJA4@558415,4NG1W@976,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
MAG.T21.18_02376	1408473.JHXO01000001_gene2242	4.9e-62	245.7	Bacteroidia	gldM												Bacteria	2G096@200643,4PKZS@976,COG4219@1,COG4219@2	NA|NA|NA	KT	Gliding motility-associated protein GldM
MAG.T21.18_02378	1453500.AT05_06815	1.6e-83	316.2	Flavobacteriia	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113		ko:K03595,ko:K06883					ko00000,ko03009,ko03029				Bacteria	1HX06@117743,4NES2@976,COG1159@1,COG1159@2	NA|NA|NA	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAG.T21.18_02379	1121931.AUHG01000019_gene3025	4.3e-154	551.2	Flavobacteriia	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363		ko:K03977					ko00000,ko03009				Bacteria	1HXD2@117743,4NE2J@976,COG1160@1,COG1160@2	NA|NA|NA	S	GTPase that plays an essential role in the late steps of ribosome biogenesis
MAG.T21.18_02380	1392490.JHZX01000001_gene869	4.4e-45	189.1	Flavobacteriia			3.4.21.72	ko:K01347					ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1HXFW@117743,4NG93@976,COG1361@1,COG1361@2,COG4886@1,COG4886@2,COG4932@1,COG4932@2	NA|NA|NA	M	regulator of chromosome condensation, RCC1
MAG.T21.18_02381	1313421.JHBV01000033_gene2389	2e-07	64.7	Bacteroidetes													Bacteria	2EXKU@1,33QWR@2,4P26S@976	NA|NA|NA	S	Domain of Unknown Function with PDB structure (DUF3857)
MAG.T21.18_02383	153721.MYP_2617	6.2e-202	711.1	Cytophagia				ko:K02014,ko:K16087					ko00000,ko02000	1.B.14,1.B.14.2			Bacteria	47M16@768503,4NFZY@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.18_02384	1123073.KB899242_gene991	4.4e-118	431.4	Xanthomonadales	mdeA		4.4.1.1,4.4.1.11,4.4.1.8	ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R01001,R01286,R02408,R04770,R04930,R04941,R09366	RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1MU9E@1224,1RXD6@1236,1XAGT@135614,COG0626@1,COG0626@2	NA|NA|NA	E	Cys/Met metabolism PLP-dependent enzyme
MAG.T21.18_02385	760192.Halhy_6511	1.1e-143	516.9	Sphingobacteriia													Bacteria	1IUX1@117747,4NE7V@976,COG1807@1,COG1807@2	NA|NA|NA	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family
MAG.T21.18_02386	929562.Emtol_2551	7.1e-101	373.6	Cytophagia													Bacteria	47XX0@768503,4PKIQ@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.18_02387	1227739.Hsw_4098	1.6e-51	209.9	Cytophagia	fjo11												Bacteria	47MRR@768503,4NEHX@976,COG0697@1,COG0697@2	NA|NA|NA	EG	PFAM EamA-like transporter family
MAG.T21.18_02389	865937.Gilli_0295	5.2e-70	271.6	Gillisia	ctaA			ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4			Bacteria	1HWUP@117743,2P74E@244698,4NEBR@976,COG1612@1,COG1612@2	NA|NA|NA	O	Cytochrome oxidase assembly protein
MAG.T21.18_02390	869213.JCM21142_93422	2.5e-29	135.6	Cytophagia	gldD												Bacteria	293VW@1,2ZRB2@2,47PUM@768503,4NMK7@976	NA|NA|NA	S	TIGRFAM gliding motility-associated lipoprotein GldD
MAG.T21.18_02391	926562.Oweho_3003	2.1e-116	426.0	Cryomorphaceae	gldE												Bacteria	1HXF3@117743,2PABH@246874,4NDZ7@976,COG1253@1,COG1253@2	NA|NA|NA	S	Transporter associated domain
MAG.T21.18_02392	1237149.C900_04530	1.5e-42	179.1	Cytophagia	ssb			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	47QZT@768503,4NQBK@976,COG0629@1,COG0629@2	NA|NA|NA	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAG.T21.18_02393	742725.HMPREF9450_00527	1e-86	327.0	Rikenellaceae	mutY			ko:K03575	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	22V04@171550,2FNMQ@200643,4NDZY@976,COG1194@1,COG1194@2	NA|NA|NA	L	NUDIX domain
MAG.T21.18_02394	1107311.Q767_07160	1.6e-24	118.6	Flavobacterium	hupA			ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	1I2WI@117743,2NWNU@237,4NT0D@976,COG0776@1,COG0776@2	NA|NA|NA	L	Belongs to the bacterial histone-like protein family
MAG.T21.18_02395	1150600.ADIARSV_2095	2.4e-12	79.0	Sphingobacteriia													Bacteria	1IQYF@117747,4NEV2@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_02397	1408433.JHXV01000008_gene145	1.4e-164	586.3	Cryomorphaceae	rng		3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394			ko00000,ko00001,ko00002,ko01000,ko03009,ko03019				Bacteria	1HWJC@117743,2PAHS@246874,4NED1@976,COG1530@1,COG1530@2	NA|NA|NA	J	Ribonuclease E/G family
MAG.T21.18_02398	879212.DespoDRAFT_01005	6.3e-60	238.4	Desulfobacterales	uvrD2												Bacteria	1QCFP@1224,2MHPD@213118,2WKAR@28221,42NH5@68525,COG0507@1,COG0507@2	NA|NA|NA	L	Helix-turn-helix domain
MAG.T21.18_02399	537011.PREVCOP_06647	1.7e-16	92.0	Bacteroidia													Bacteria	2FVJ2@200643,4NV8D@976,COG2361@1,COG2361@2	NA|NA|NA	S	Protein of unknown function DUF86
MAG.T21.18_02400	1288963.ADIS_1727	5.5e-25	120.2	Cytophagia				ko:K07075					ko00000				Bacteria	47SUF@768503,4NVFY@976,COG1669@1,COG1669@2	NA|NA|NA	S	Nucleotidyltransferase domain
MAG.T21.18_02401	1538644.KO02_06415	3e-25	121.7	Sphingobacteriia	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100		R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400		GT4		Bacteria	1ITI6@117747,4NSAS@976,COG2137@1,COG2137@2	NA|NA|NA	S	Modulates RecA activity
MAG.T21.18_02402	1235803.C825_01515	3.5e-47	195.7	Porphyromonadaceae													Bacteria	22YA0@171551,2FQXS@200643,4NHPW@976,COG3177@1,COG3177@2	NA|NA|NA	K	Fic/DOC family
MAG.T21.18_02403	929556.Solca_3036	1.3e-53	215.7	Sphingobacteriia	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904		ko:K02950	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IS0J@117747,4NM3Y@976,COG0048@1,COG0048@2	NA|NA|NA	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAG.T21.18_02404	755732.Fluta_0782	4.9e-52	210.7	Cryomorphaceae	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02992	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1HWP7@117743,2PAQE@246874,4NEEM@976,COG0049@1,COG0049@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAG.T21.18_02405	926562.Oweho_0543	1.3e-19	102.1	Cryomorphaceae			4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYQY@117743,2PBN1@246874,4NEVN@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2	NA|NA|NA	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family
MAG.T21.18_02407	471854.Dfer_1121	3.1e-09	67.8	Cytophagia													Bacteria	2EKHJ@1,33E7I@2,47WYG@768503,4P6IY@976	NA|NA|NA		
MAG.T21.18_02409	1173020.Cha6605_3031	9.9e-94	351.3	Cyanobacteria	nucH		3.1.3.1	ko:K01077,ko:K07004	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	1G0YK@1117,COG2374@1,COG2374@2,COG3391@1,COG3391@2	NA|NA|NA	K	phosphatase
MAG.T21.18_02410	1288494.EBAPG3_17370	2.9e-26	125.2	Betaproteobacteria													Bacteria	1RJ1C@1224,2WEK0@28216,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02411	402881.Plav_1072	5.7e-35	153.7	Alphaproteobacteria	ybaA		3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	1RHC1@1224,2UC7A@28211,COG5507@1,COG5507@2	NA|NA|NA	S	RNA signal recognition particle 4.5S RNA
MAG.T21.18_02412	760192.Halhy_4897	2.1e-24	118.6	Sphingobacteriia													Bacteria	1J0F3@117747,31BQE@2,4PQ0A@976,COG2259@1	NA|NA|NA	S	DoxX-like family
MAG.T21.18_02413	404589.Anae109_0604	2.2e-30	138.7	Proteobacteria													Bacteria	1MZ7K@1224,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase
MAG.T21.18_02414	1292034.OR37_03705	8.5e-24	116.7	Caulobacterales													Bacteria	1NKMZ@1224,2KJ5I@204458,2UJHW@28211,COG5646@1,COG5646@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_02415	626887.J057_02365	4e-37	161.0	Gammaproteobacteria				ko:K07032					ko00000				Bacteria	1RH1T@1224,1S6FE@1236,COG3607@1,COG3607@2	NA|NA|NA	S	glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.18_02416	794846.AJQU01000029_gene4211	1e-33	149.8	Rhizobiaceae													Bacteria	1RJ7U@1224,2U9W0@28211,4BE9Z@82115,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02417	378806.STAUR_7236	1.8e-51	209.1	Myxococcales													Bacteria	1NEN6@1224,2X9ZT@28221,2YUYI@29,4386R@68525,COG4430@1,COG4430@2	NA|NA|NA	S	Bacteriocin-protection, YdeI or OmpD-Associated
MAG.T21.18_02418	530564.Psta_1705	1.8e-51	209.5	Planctomycetes													Bacteria	2IZ0C@203682,COG4912@1,COG4912@2	NA|NA|NA	L	DNA alkylation repair enzyme
MAG.T21.18_02419	697282.Mettu_0557	3.2e-35	154.8	Methylococcales													Bacteria	1N06E@1224,1SFTG@1236,1XGBH@135618,COG4978@1,COG4978@2	NA|NA|NA	KT	PFAM Bacterial transcription activator, effector binding
MAG.T21.18_02420	1254432.SCE1572_25290	4.6e-19	100.9	Myxococcales													Bacteria	1R0CX@1224,2X83I@28221,2YVP8@29,43CVJ@68525,COG5646@1,COG5646@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.18_02421	639030.JHVA01000001_gene1931	3.6e-42	177.9	Acidobacteriia				ko:K02005					ko00000				Bacteria	2JNZQ@204432,3Y7X4@57723,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02422	670307.HYPDE_36668	1.1e-31	143.3	Hyphomicrobiaceae	gstF		2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418		R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2			Bacteria	1MZXG@1224,2UBQP@28211,3N8Y8@45401,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02423	485918.Cpin_6720	6.4e-43	180.3	Sphingobacteriia													Bacteria	1ISRX@117747,4NQ4A@976,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase
MAG.T21.18_02424	1121373.KB903629_gene337	2.3e-50	204.9	Cytophagia	arr			ko:K19062,ko:K21288					ko00000,ko01504				Bacteria	2DK0G@1,30823@2,47R5W@768503,4NNIV@976	NA|NA|NA	S	Rifampin ADP-ribosyl transferase
MAG.T21.18_02425	485918.Cpin_4571	1.7e-50	205.7	Sphingobacteriia				ko:K04750					ko00000				Bacteria	1IPXU@117747,4NFVK@976,COG2764@1,COG2764@2,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02426	1210884.HG799471_gene14625	1.7e-39	169.1	Planctomycetes													Bacteria	2J16I@203682,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02427	1123073.KB899242_gene1024	2.5e-38	164.9	Xanthomonadales													Bacteria	1RH5P@1224,1S9NT@1236,1X7N9@135614,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
MAG.T21.18_02428	313606.M23134_02452	1.1e-253	883.2	Cytophagia													Bacteria	47KZ5@768503,4NDYB@976,COG3537@1,COG3537@2	NA|NA|NA	G	PFAM Glycosyl Hydrolase
MAG.T21.18_02429	903818.KI912268_gene3202	2e-33	148.7	Acidobacteria				ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	3Y8G5@57723,COG0614@1,COG0614@2	NA|NA|NA	P	PD-(D/E)XK nuclease superfamily
MAG.T21.18_02430	470145.BACCOP_00253	3.4e-63	248.8	Bacteroidaceae	glk		2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2FNGN@200643,4AMRT@815,4NFZ1@976,COG1940@1,COG1940@2	NA|NA|NA	GK	Psort location Cytoplasmic, score 9.26
MAG.T21.18_02431	946077.W5A_03724	1.1e-136	493.4	Flavobacteriia	gluP			ko:K02429					ko00000,ko02000	2.A.1.7			Bacteria	1HY8N@117743,4NEYR@976,COG0738@1,COG0738@2	NA|NA|NA	G	Transporter
MAG.T21.18_02432	525257.HMPREF0204_14584	1.4e-96	359.8	Chryseobacterium	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142		R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002				Bacteria	1HXFB@117743,3ZP3J@59732,4NE3D@976,COG1446@1,COG1446@2	NA|NA|NA	E	Glycosylasparaginase
MAG.T21.18_02435	755732.Fluta_3944	2.6e-34	152.1	Cryomorphaceae				ko:K03088					ko00000,ko03021				Bacteria	1IIVT@117743,2PBR9@246874,4NT79@976,COG1595@1,COG1595@2	NA|NA|NA	K	ECF sigma factor
MAG.T21.18_02436	1313421.JHBV01000049_gene63	8.1e-08	65.1	Bacteroidetes													Bacteria	4NW0B@976,COG1262@1,COG1262@2	NA|NA|NA	S	PFAM Formylglycine-generating sulfatase enzyme
MAG.T21.18_02437	926562.Oweho_0417	2.7e-10	71.2	Cryomorphaceae	ybeD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K09158					ko00000				Bacteria	1IGIZ@117743,2PB80@246874,4PA5G@976,COG2921@1,COG2921@2	NA|NA|NA	S	Protein of unknown function (DUF493)
MAG.T21.18_02440	1123035.ARLA01000023_gene1188	0.0	1109.4	Flavobacteriia	ppsA		2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000				Bacteria	1HY80@117743,4NEHE@976,COG0574@1,COG0574@2,COG1080@1,COG1080@2	NA|NA|NA	G	Belongs to the PEP-utilizing enzyme family
MAG.T21.18_02441	1122176.KB903537_gene1608	1e-41	178.3	Bacteria													Bacteria	COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG5184@1,COG5184@2	NA|NA|NA	DZ	guanyl-nucleotide exchange factor activity
MAG.T21.18_02443	1396141.BATP01000040_gene2069	1.7e-56	226.1	Verrucomicrobia													Bacteria	46WTT@74201,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase domain
MAG.T21.18_02444	491205.JARQ01000001_gene1074	3.9e-86	326.6	Chryseobacterium	ppiA		2.3.1.31,5.2.1.8	ko:K00641,ko:K03767,ko:K03768	ko00270,ko01100,ko01130,ko01503,ko04217,map00270,map01100,map01130,map01503,map04217		R01776	RC00004,RC00041	ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	1HZ0K@117743,3ZNHV@59732,4NHTI@976,COG0652@1,COG0652@2,COG3023@1,COG3023@2,COG3292@1,COG3292@2	NA|NA|NA	T	Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein.
MAG.T21.18_02445	411154.GFO_1541	2.3e-34	153.3	Flavobacteriia	gshA		6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXM0@117743,4NGA3@976,COG2170@1,COG2170@2	NA|NA|NA	S	Glutamate-cysteine ligase family 2(GCS2)
MAG.T21.18_02446	382464.ABSI01000011_gene2473	2.4e-23	116.3	Verrucomicrobia			3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3	ko:K01179,ko:K01361,ko:K01637,ko:K01729,ko:K09942,ko:K20276	ko00051,ko00500,ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00051,map00500,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479,R03706,R06200,R11307,R11308	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110		GH5,GH9		Bacteria	46W6Z@74201,COG0028@1,COG0028@2,COG1404@1,COG1404@2,COG2885@1,COG2885@2,COG3210@1,COG3210@2,COG3291@1,COG3291@2,COG3391@1,COG3391@2,COG3507@1,COG3507@2,COG4733@1,COG4733@2,COG4935@1,COG4935@2,COG5295@1,COG5295@2	NA|NA|NA	GMOU	Fibronectin type 3 domain
MAG.T21.18_02447	502025.Hoch_0068	1.1e-27	132.5	Myxococcales			3.4.24.25	ko:K08604	ko05110,ko05111,map05110,map05111				ko00000,ko00001,ko01000,ko01002				Bacteria	1Q6DC@1224,2WYJ7@28221,2Z34H@29,432XR@68525,COG3227@1,COG3227@2	NA|NA|NA	E	Zinc metalloprotease (Elastase)
MAG.T21.18_02448	1313301.AUGC01000004_gene2420	1.3e-78	299.7	Bacteroidetes	phnP		2.3.1.181,3.1.4.55	ko:K03801,ko:K06167	ko00440,ko00785,ko01100,map00440,map00785,map01100		R07766,R07769,R10205	RC00039,RC00296,RC00992,RC02867	ko00000,ko00001,ko01000				Bacteria	4NDWB@976,COG1235@1,COG1235@2	NA|NA|NA	S	of the beta-lactamase superfamily I
MAG.T21.18_02451	1249997.JHZW01000002_gene192	2.5e-141	508.8	Maribacter	nhaD												Bacteria	1HYB2@117743,2PGGP@252356,4NGP4@976,COG1055@1,COG1055@2	NA|NA|NA	P	Citrate transporter
MAG.T21.18_02452	1313421.JHBV01000042_gene3290	4.9e-134	484.6	Sphingobacteriia	nhaD												Bacteria	1IVHN@117747,4NGP4@976,COG1055@1,COG1055@2	NA|NA|NA	P	COG1055 Na H antiporter NhaD and related arsenite
MAG.T21.18_02454	1121957.ATVL01000006_gene2618	4.2e-44	185.7	Cytophagia			2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100		R00292	RC00005	ko00000,ko00001,ko01000,ko01003		GT4		Bacteria	47S2Z@768503,4NFPA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase Family 4
MAG.T21.18_02455	1090319.KE386571_gene2976	8.2e-27	128.6	Sphingomonadales	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000			iSFV_1184.SFV_2325	Bacteria	1NN5V@1224,2K41C@204457,2TTHZ@28211,COG0223@1,COG0223@2	NA|NA|NA	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAG.T21.18_02456	1356852.N008_10585	5e-43	182.2	Cytophagia													Bacteria	47XRY@768503,4NRKF@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis C-terminal domain
MAG.T21.18_02457	1227739.Hsw_2128	1.7e-72	279.3	Cytophagia	bshB1			ko:K01463					ko00000,ko01000				Bacteria	47K51@768503,4NEDJ@976,COG2120@1,COG2120@2	NA|NA|NA	S	PFAM GlcNAc-PI de-N-acetylase
MAG.T21.18_02458	926562.Oweho_0197	5.6e-50	204.1	Cryomorphaceae	btuE		1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918		R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000				Bacteria	1I1AR@117743,2PB07@246874,4NM6G@976,COG0386@1,COG0386@2	NA|NA|NA	O	Belongs to the glutathione peroxidase family
MAG.T21.18_02460	929562.Emtol_1785	3.1e-121	442.2	Cytophagia				ko:K07576					ko00000				Bacteria	47K9F@768503,4NESD@976,COG1236@1,COG1236@2	NA|NA|NA	J	exonuclease of the beta-lactamase fold involved in RNA processing
MAG.T21.18_02461	391587.KAOT1_18387	3.5e-19	103.2	Flavobacteriia													Bacteria	1HY1V@117743,4NDZC@976,COG3291@1,COG3291@2	NA|NA|NA	DZ	adhesin AidA-related
MAG.T21.18_02462	1121889.AUDM01000008_gene710	8.3e-46	192.2	Flavobacterium													Bacteria	1I3RW@117743,2NUN2@237,4NJQ1@976,COG2911@1,COG2911@2	NA|NA|NA	O	C-terminal domain of CHU protein family
MAG.T21.18_02463	1123248.KB893337_gene2408	5.3e-14	86.3	Bacteria													Bacteria	COG0729@1,COG0729@2,COG3210@1,COG3210@2	NA|NA|NA	M	surface antigen
MAG.T21.18_02464	1408813.AYMG01000009_gene3132	5.2e-18	98.2	Sphingobacteriia													Bacteria	1IS43@117747,4NJW3@976,COG2197@1,COG2197@2	NA|NA|NA	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.18_02466	1227352.C173_13580	1.6e-211	743.0	Paenibacillaceae			3.1.3.5,3.2.1.4	ko:K01081,ko:K01173,ko:K01179,ko:K06931	ko00230,ko00240,ko00500,ko00760,ko01100,ko01110,ko04210,map00230,map00240,map00500,map00760,map01100,map01110,map04210		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R06200,R11307,R11308	RC00017	ko00000,ko00001,ko01000,ko03029		GH5,GH9		Bacteria	1V15Q@1239,26XUP@186822,4HEHE@91061,COG2356@1,COG2356@2,COG2374@1,COG2374@2,COG3591@1,COG3591@2	NA|NA|NA	L	Endonuclease I
MAG.T21.18_02468	1453505.JASY01000003_gene2218	8.4e-86	323.6	Flavobacteriia													Bacteria	1I7X8@117743,2EB2W@1,2ZAVB@2,4NN40@976	NA|NA|NA	S	Zinc-dependent metalloprotease
MAG.T21.18_02469	880070.Cycma_0622	8.8e-17	93.6	Bacteria													Bacteria	2FI9K@1,34A21@2	NA|NA|NA		
MAG.T21.18_02471	362418.IW19_19840	3e-27	129.8	Flavobacteriia													Bacteria	1I97S@117743,2CDC2@1,339FA@2,4NWTF@976	NA|NA|NA		
MAG.T21.18_02473	767817.Desgi_1008	2.7e-240	837.8	Peptococcaceae			2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,247RY@186801,26092@186807,COG0286@1,COG0286@2	NA|NA|NA	V	PFAM N-6 DNA methylase
MAG.T21.18_02474	879212.DespoDRAFT_00358	1e-90	340.5	Desulfobacterales			3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	1MXSQ@1224,2MKV3@213118,2WQWU@28221,42UK5@68525,COG0732@1,COG0732@2	NA|NA|NA	L	PFAM Type I restriction modification DNA specificity domain
MAG.T21.18_02475	761193.Runsl_3914	3.1e-99	369.8	Cytophagia													Bacteria	2EQ7Y@1,33HU6@2,47WEW@768503,4NXWG@976	NA|NA|NA		
MAG.T21.18_02476	266264.Rmet_5467	6.5e-28	131.7	Proteobacteria													Bacteria	1NSGF@1224,2B1FR@1,31TWH@2	NA|NA|NA		
MAG.T21.18_02478	1121898.Q766_20190	9.2e-230	803.9	Bacteria													Bacteria	COG0553@1,COG0553@2	NA|NA|NA	L	helicase activity
MAG.T21.18_02479	331678.Cphamn1_0131	1.2e-62	246.9	Chlorobi													Bacteria	1FF2M@1090,COG0551@1,COG0551@2	NA|NA|NA	L	PFAM DNA topoisomerase type IA zn finger domain protein
MAG.T21.18_02480	1485544.JQKP01000005_gene337	0.0	1637.5	Nitrosomonadales	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1MU96@1224,2VHIR@28216,44VE5@713636,COG0610@1,COG0610@2	NA|NA|NA	L	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAG.T21.18_02481	1250278.JQNQ01000001_gene2041	9.9e-40	169.9	Flavobacteriia													Bacteria	1I1X8@117743,29ZD6@1,30MBZ@2,4NNZI@976	NA|NA|NA		
MAG.T21.18_02483	1223410.KN050846_gene2532	3.2e-17	96.3	Flavobacteriia													Bacteria	1I8V8@117743,4P2SE@976,COG3391@1,COG3391@2	NA|NA|NA	S	amine dehydrogenase activity
MAG.T21.18_02484	1123248.KB893328_gene941	1.2e-64	254.2	Sphingobacteriia													Bacteria	1IX26@117747,4NK33@976,COG3291@1,COG3291@2,COG3386@1,COG3386@2	NA|NA|NA	G	domain, Protein
MAG.T21.18_02486	1121007.AUML01000001_gene1414	1.1e-30	141.0	Aquimarina													Bacteria	1HWWD@117743,28I9R@1,2YI4N@290174,2Z8CE@2,4NE54@976	NA|NA|NA	S	Lipid A 3-O-deacylase (PagL)
MAG.T21.18_02487	313606.M23134_01415	1.5e-15	90.1	Cytophagia													Bacteria	47SA4@768503,4PMD5@976,COG3595@1,COG3595@2	NA|NA|NA	S	Putative auto-transporter adhesin, head GIN domain
MAG.T21.18_02488	1089550.ATTH01000001_gene1159	7.4e-55	220.7	Bacteroidetes Order II. Incertae sedis													Bacteria	1FJ9F@1100069,4NMX4@976,COG3332@1,COG3332@2	NA|NA|NA	S	Transport and Golgi organisation 2
MAG.T21.18_02490	1123248.KB893370_gene4971	6.8e-44	183.7	Sphingobacteriia	yajQ	GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K09767					ko00000				Bacteria	1IRSS@117747,4NMBZ@976,COG1666@1,COG1666@2	NA|NA|NA	S	Belongs to the UPF0234 family
MAG.T21.18_02491	1408433.JHXV01000023_gene3302	2.9e-78	299.7	Cryomorphaceae				ko:K03933					ko00000		AA10,CBM73		Bacteria	1ICPP@117743,2PBJ2@246874,4PBW3@976,COG3291@1,COG3291@2	NA|NA|NA	S	PA domain
MAG.T21.18_02492	1121129.KB903367_gene2764	1.1e-109	403.3	Porphyromonadaceae	arnC		2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100		R01009	RC00005	ko00000,ko00001,ko01000,ko01003		GT2		Bacteria	22WFA@171551,2FMV7@200643,4NEVT@976,COG0463@1,COG0463@2	NA|NA|NA	M	glycosyl transferase family 2
MAG.T21.18_02493	870187.Thini_1261	3.8e-23	116.3	Gammaproteobacteria													Bacteria	1NIAW@1224,1SGWV@1236,2DBRU@1,2ZANA@2	NA|NA|NA		
MAG.T21.18_02494	1122621.ATZA01000006_gene686	4.2e-114	418.7	Sphingobacteriia	ycbB			ko:K21470					ko00000,ko01002,ko01011				Bacteria	1IRD3@117747,4NH3J@976,COG2989@1,COG2989@2	NA|NA|NA	S	ErfK YbiS YcfS YnhG family protein
MAG.T21.18_02495	929562.Emtol_2837	1.3e-34	153.3	Cytophagia													Bacteria	47NYB@768503,4NNX7@976,COG1376@1,COG1376@2	NA|NA|NA	S	L,D-transpeptidase catalytic domain
MAG.T21.18_02496	760192.Halhy_0941	6.8e-139	500.7	Sphingobacteriia													Bacteria	1IPPF@117747,4NEZI@976,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferase, group 1
MAG.T21.18_02497	760192.Halhy_0940	5.5e-134	484.2	Bacteria			1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100		R05692	RC01014	ko00000,ko00001,ko01000				Bacteria	COG0451@1,COG0451@2	NA|NA|NA	GM	ADP-glyceromanno-heptose 6-epimerase activity
MAG.T21.18_02498	1408433.JHXV01000009_gene1349	6.6e-80	304.7	Cryomorphaceae	rsbU		3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021				Bacteria	1IMQG@117743,2PBAV@246874,4NI98@976,COG2208@1,COG2208@2	NA|NA|NA	KT	Sigma factor PP2C-like phosphatases
MAG.T21.18_02499	1127692.HMPREF9075_01003	3.4e-70	271.9	Capnocytophaga	lpxD		2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1EQUU@1016,1HXWG@117743,4NFXA@976,COG1044@1,COG1044@2	NA|NA|NA	I	UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase
MAG.T21.18_02500	153721.MYP_3528	1.8e-56	225.7	Cytophagia	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02356					ko00000,ko03012				Bacteria	47MZS@768503,4NDXA@976,COG0231@1,COG0231@2	NA|NA|NA	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAG.T21.18_02501	485917.Phep_1566	1e-33	149.1	Sphingobacteriia	rpmE2	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02909	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ITGS@117747,4NS7P@976,COG0254@1,COG0254@2	NA|NA|NA	J	Ribosomal protein L31
MAG.T21.18_02502	204669.Acid345_3121	1.7e-20	106.3	Acidobacteriia													Bacteria	2JJNK@204432,3Y5B3@57723,COG4430@1,COG4430@2	NA|NA|NA	S	Bacteriocin-protection, YdeI or OmpD-Associated
MAG.T21.18_02503	926562.Oweho_2249	1.3e-160	572.8	Cryomorphaceae	pcaF	GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016740,GO:0016746,GO:0016747,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033554,GO:0033812,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K00632,ko:K02615,ko:K07823	ko00071,ko00072,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00360,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095,R09839	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1HWZU@117743,2PA9T@246874,4NE3Q@976,COG0183@1,COG0183@2	NA|NA|NA	I	Thiolase, C-terminal domain
MAG.T21.18_02504	926562.Oweho_2251	1.9e-37	162.2	Cryomorphaceae	paaI	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790		ko:K02614	ko00360,map00360		R09840	RC00004,RC00014	ko00000,ko00001,ko01000			iBWG_1329.BWG_1225,iEC55989_1330.EC55989_1532,iECDH10B_1368.ECDH10B_1521,iECDH1ME8569_1439.EcDH1_2249,iECIAI1_1343.ECIAI1_1396,iECO103_1326.ECO103_1533,iECO111_1330.ECO111_1790,iECO26_1355.ECO26_2000,iECSE_1348.ECSE_1481,iEKO11_1354.EKO11_2417,iETEC_1333.ETEC_1471,iEcDH1_1363.EcDH1_2249,iEcE24377_1341.EcE24377A_1581,iEcHS_1320.EcHS_A1483,iEcolC_1368.EcolC_2259,iUMNK88_1353.UMNK88_1803,iY75_1357.Y75_RS07340	Bacteria	1I2P9@117743,2PB1D@246874,4NM7W@976,COG2050@1,COG2050@2	NA|NA|NA	Q	Thioesterase superfamily
MAG.T21.18_02505	768066.HELO_1506	2.4e-36	158.7	Oceanospirillales	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567,ko:K10778					ko00000,ko01000,ko03000,ko03400				Bacteria	1N2YQ@1224,1S68H@1236,1XKJA@135619,COG0350@1,COG0350@2	NA|NA|NA	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MAG.T21.18_02506	1443665.JACA01000013_gene4268	3.4e-54	218.4	Aquimarina													Bacteria	1I8TV@117743,2YIDA@290174,4NRNM@976,COG5587@1,COG5587@2	NA|NA|NA	S	Conserved hypothetical protein (DUF2461)
MAG.T21.18_02507	1121373.KB903654_gene1610	2.8e-24	119.0	Cytophagia													Bacteria	47PZ0@768503,4NMWH@976,COG2353@1,COG2353@2	NA|NA|NA	S	Belongs to the UPF0312 family
MAG.T21.18_02508	984262.SGRA_p0040	9.8e-134	483.4	Bacteroidetes	paaH		1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000				Bacteria	4NF2W@976,COG1250@1,COG1250@2	NA|NA|NA	I	Dehydrogenase
MAG.T21.18_02509	518766.Rmar_1551	6.7e-78	297.4	Bacteroidetes	paaG	GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120		R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000			iECO103_1326.ECO103_1531,iJN746.PP_3283,iYL1228.KPN_01475	Bacteria	4NHRF@976,COG1024@1,COG1024@2	NA|NA|NA	I	Belongs to the enoyl-CoA hydratase isomerase family
MAG.T21.18_02510	925409.KI911562_gene1788	8.6e-102	377.1	Sphingobacteriia				ko:K02843	ko00540,ko01100,map00540,map01100	M00080			ko00000,ko00001,ko00002,ko01000,ko01003,ko01005		GT9		Bacteria	1IWTZ@117747,4PKBY@976,COG0859@1,COG0859@2	NA|NA|NA	M	Glycosyltransferase family 9 (heptosyltransferase)
MAG.T21.18_02511	1392490.JHZX01000001_gene3250	7.6e-93	347.1	Flavobacteriia	dapD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000			iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180	Bacteria	1HWTI@117743,4NEWD@976,COG2171@1,COG2171@2	NA|NA|NA	E	Belongs to the transferase hexapeptide repeat family
MAG.T21.18_02512	1279009.ADICEAN_00615	8.5e-32	143.3	Cytophagia	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360		ko:K07447					ko00000,ko01000				Bacteria	47QCM@768503,4NQ8B@976,COG0816@1,COG0816@2	NA|NA|NA	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAG.T21.18_02516	313596.RB2501_15809	8.2e-207	727.2	Flavobacteriia	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_2160,iPC815.YPO2428	Bacteria	1HX4I@117743,4NF5B@976,COG0072@1,COG0072@2,COG0073@1,COG0073@2	NA|NA|NA	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAG.T21.18_02517	1233950.IW22_18365	3.1e-12	80.1	Bacteroidetes													Bacteria	4PNEQ@976,COG4733@1,COG4733@2	NA|NA|NA	S	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02518	509635.N824_23620	7e-111	407.5	Sphingobacteriia													Bacteria	1IXQU@117747,4NFWX@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.18_02519	1123037.AUDE01000024_gene1637	1.7e-22	113.2	Flavobacteriia													Bacteria	1I1IJ@117743,4NMZ9@976,COG3714@1,COG3714@2	NA|NA|NA	S	YhhN family
MAG.T21.18_02520	1406840.Q763_03325	1.8e-234	818.9	Flavobacterium	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1HX1Z@117743,2NT3Q@237,4NDZV@976,COG1200@1,COG1200@2	NA|NA|NA	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAG.T21.18_02522	1122176.KB903556_gene4079	2.6e-63	249.2	Sphingobacteriia													Bacteria	1J19Z@117747,4NX61@976,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_02523	1121373.KB903665_gene2976	6.4e-42	177.2	Cytophagia													Bacteria	47VH4@768503,4NNT1@976,COG4430@1,COG4430@2	NA|NA|NA	S	Domain of unknown function (DUF1905)
MAG.T21.18_02524	1123487.KB892841_gene4254	9.4e-27	127.9	Rhodocyclales			3.4.21.107	ko:K04771,ko:K07126	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1RDHW@1224,2KZ9R@206389,2VRY7@28216,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like peptidase domain
MAG.T21.18_02525	861299.J421_0700	4.9e-34	151.0	Bacteria			3.6.1.55,5.5.1.4	ko:K01858,ko:K03207,ko:K03574	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130		R07324	RC01804	ko00000,ko00001,ko01000,ko03400				Bacteria	COG0454@1,COG0456@2,COG1051@1,COG1051@2	NA|NA|NA	K	acetyltransferase
MAG.T21.18_02526	714943.Mucpa_3747	9.1e-23	114.4	Sphingobacteriia	J			ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	1IZ2D@117747,4NTXR@976,COG4733@1,COG4733@2	NA|NA|NA	S	Concanavalin A-like lectin/glucanases superfamily
MAG.T21.18_02527	285535.JOEY01000015_gene4211	9.7e-29	135.2	Actinobacteria													Bacteria	2GKNI@201174,COG1572@1,COG1572@2,COG2931@1,COG2931@2	NA|NA|NA	Q	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02528	313606.M23134_05174	1.3e-31	143.7	Bacteroidetes													Bacteria	4NHA5@976,COG2207@1,COG2207@2	NA|NA|NA	K	AraC family
MAG.T21.18_02529	435908.IDSA_09340	9.5e-28	129.8	Idiomarinaceae													Bacteria	1NCJP@1224,1SB4D@1236,29E7I@1,2QGVA@267893,3015I@2	NA|NA|NA	S	Protein of unknown function (DUF1761)
MAG.T21.18_02530	1223410.KN050846_gene2286	1.4e-69	270.0	Flavobacteriia				ko:K03641					ko00000,ko02000	2.C.1.2			Bacteria	1IIJA@117743,4NN6B@976,COG0823@1,COG0823@2	NA|NA|NA	U	WD40-like Beta Propeller Repeat
MAG.T21.18_02531	1107311.Q767_01615	2.9e-65	257.3	Flavobacterium				ko:K12287,ko:K14274	ko00040,map00040		R02427	RC00713	ko00000,ko00001,ko01000,ko02044				Bacteria	1IKME@117743,2NXAD@237,4NNUN@976,COG1520@1,COG1520@2,COG3291@1,COG3291@2,COG3386@1,COG3386@2,COG5306@1,COG5306@2	NA|NA|NA	G	PFAM SMP-30 Gluconolaconase
MAG.T21.18_02532	1317122.ATO12_18560	5.6e-33	147.5	Aquimarina			1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000				Bacteria	1I2QW@117743,2YID3@290174,4NNNU@976,COG1053@1,COG1053@2	NA|NA|NA	C	ankyrin repeats
MAG.T21.18_02533	1123400.KB904765_gene1396	8.5e-29	135.6	Proteobacteria													Bacteria	1QUSE@1224,COG0823@1,COG0823@2,COG1361@1,COG1361@2,COG2706@1,COG2706@2,COG2834@1,COG2834@2,COG3291@1,COG3291@2,COG5384@1,COG5384@2	NA|NA|NA	G	PFAM FecR protein
MAG.T21.18_02534	1237149.C900_04154	1.8e-97	362.5	Cytophagia	dinD			ko:K07741,ko:K14623					ko00000,ko03400				Bacteria	47TBU@768503,4NJ37@976,COG3645@1,COG3645@2	NA|NA|NA	S	DNA-damage-inducible protein D
MAG.T21.18_02535	452637.Oter_2612	1.9e-40	172.6	Verrucomicrobia													Bacteria	46VCW@74201,COG0457@1,COG0457@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.18_02536	1122225.AULQ01000001_gene1833	9.3e-100	370.2	Flavobacteriia													Bacteria	1HWV1@117743,4NHAD@976,COG1801@1,COG1801@2	NA|NA|NA	S	Protein of unknown function DUF72
MAG.T21.18_02537	1144275.COCOR_07194	2e-17	94.7	Proteobacteria													Bacteria	1N4FB@1224,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
MAG.T21.18_02538	84531.JMTZ01000012_gene3007	7.8e-49	200.3	Xanthomonadales													Bacteria	1RHJJ@1224,1S850@1236,1X741@135614,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.18_02539	927658.AJUM01000044_gene656	2.1e-93	349.4	Marinilabiliaceae													Bacteria	2FNH4@200643,3XINX@558415,4NEHG@976,COG2374@1,COG2374@2	NA|NA|NA	S	Endonuclease exonuclease phosphatase family
MAG.T21.18_02541	1408433.JHXV01000007_gene2956	2.8e-55	222.2	Cryomorphaceae	ybfF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689		ko:K01175					ko00000,ko01000				Bacteria	1HXF6@117743,2PAPJ@246874,4NDZI@976,COG0596@1,COG0596@2	NA|NA|NA	S	Serine aminopeptidase, S33
MAG.T21.18_02542	880526.KE386488_gene1494	1e-83	316.6	Rikenellaceae	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000				Bacteria	22U2C@171550,2FM21@200643,4NF4Z@976,COG0854@1,COG0854@2	NA|NA|NA	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MAG.T21.18_02543	1408433.JHXV01000007_gene2958	4.7e-48	198.0	Cryomorphaceae													Bacteria	1HXW4@117743,2PAZY@246874,4NF8G@976,COG0517@1,COG0517@2	NA|NA|NA	S	CBS domain
MAG.T21.18_02544	1237149.C900_01627	1.5e-72	280.4	Cytophagia													Bacteria	47KUK@768503,4NF9Y@976,COG4775@1,COG4775@2	NA|NA|NA	M	PFAM surface antigen variable number repeat
MAG.T21.18_02545	1358423.N180_14765	5.3e-68	264.6	Sphingobacteriia	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100		R00104	RC00002,RC00078	ko00000,ko00001,ko01000			iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	Bacteria	1IPBF@117747,4NFG5@976,COG0061@1,COG0061@2	NA|NA|NA	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAG.T21.18_02546	1408433.JHXV01000001_gene693	4.7e-45	188.3	Cryomorphaceae				ko:K12976					ko00000,ko01000,ko01005				Bacteria	1IC3X@117743,2PB1K@246874,4NUEN@976,COG3637@1,COG3637@2	NA|NA|NA	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MAG.T21.18_02547	760192.Halhy_2492	1.2e-79	303.1	Sphingobacteriia	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110		R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006			iLJ478.TM1398	Bacteria	1IPRJ@117747,4NF2B@976,COG0020@1,COG0020@2	NA|NA|NA	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAG.T21.18_02548	926562.Oweho_2775	2.5e-214	752.3	Cryomorphaceae	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063		ko:K07277					ko00000,ko02000,ko03029	1.B.33			Bacteria	1HWVA@117743,2PAC5@246874,4NE6Z@976,COG4775@1,COG4775@2	NA|NA|NA	M	TIGRFAM outer membrane protein assembly complex, YaeT protein
MAG.T21.18_02549	485918.Cpin_1053	7.9e-35	154.1	Sphingobacteriia	ompH			ko:K06142					ko00000				Bacteria	1IS3M@117747,4NH46@976,COG2825@1,COG2825@2	NA|NA|NA	M	outer membrane chaperone Skp (OmpH)
MAG.T21.18_02550	929556.Solca_0564	7.1e-23	114.0	Sphingobacteriia	ompH			ko:K06142					ko00000				Bacteria	1ITN8@117747,4NSCM@976,COG2825@1,COG2825@2	NA|NA|NA	M	PFAM outer membrane chaperone Skp (OmpH)
MAG.T21.18_02551	926569.ANT_04560	1.5e-72	279.6	Chloroflexi	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100		R00260	RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	2G8GN@200795,COG0796@1,COG0796@2	NA|NA|NA	M	Provides the (R)-glutamate required for cell wall biosynthesis
MAG.T21.18_02552	313596.RB2501_03445	5.5e-52	210.7	Flavobacteriia	dapH												Bacteria	1HYG2@117743,4NG6R@976,COG0663@1,COG0663@2	NA|NA|NA	S	isoleucine patch superfamily
MAG.T21.18_02553	1089547.KB913013_gene3743	1.4e-14	85.9	Cytophagia				ko:K08364					ko00000,ko02000	1.A.72.1			Bacteria	47S0M@768503,4NUTQ@976,COG2608@1,COG2608@2	NA|NA|NA	P	PFAM Heavy metal transport detoxification protein
MAG.T21.18_02554	1121129.KB903360_gene3187	3.9e-134	485.7	Porphyromonadaceae				ko:K16089					ko00000,ko02000	1.B.14.1,1.B.14.10			Bacteria	22X8W@171551,2FQ61@200643,4NE7A@976,COG1629@1,COG4771@2	NA|NA|NA	P	CarboxypepD_reg-like domain
MAG.T21.18_02556	1408433.JHXV01000001_gene1087	2.4e-293	1014.6	Cryomorphaceae	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYI9@117743,2PB53@246874,4NETY@976,COG0046@1,COG0046@2	NA|NA|NA	F	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
MAG.T21.18_02557	246196.MSMEI_3398	1.1e-33	149.8	Mycobacteriaceae	tpx	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K11065					ko00000,ko01000				Bacteria	233ZP@1762,2II20@201174,COG2077@1,COG2077@2	NA|NA|NA	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAG.T21.18_02558	411477.PARMER_03297	7.3e-27	127.1	Porphyromonadaceae				ko:K03088					ko00000,ko03021				Bacteria	22Y4K@171551,2FMT6@200643,4NSVA@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.18_02559	1168034.FH5T_01410	2.2e-07	62.0	Bacteroidetes													Bacteria	2EFPT@1,339FT@2,4NV1V@976	NA|NA|NA		
MAG.T21.18_02560	746697.Aeqsu_1125	3.4e-48	198.7	Flavobacteriia	mtgA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.129,3.4.16.4	ko:K03814,ko:K05365	ko00550,map00550		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1HXMN@117743,4NF90@976,COG0744@1,COG0744@2	NA|NA|NA	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MAG.T21.18_02561	313628.LNTAR_24319	1.5e-67	263.5	Bacteria	mscS			ko:K16052					ko00000,ko02000	1.A.23.4			Bacteria	COG0668@1,COG0668@2	NA|NA|NA	M	transmembrane transport
MAG.T21.18_02562	1122621.ATZA01000012_gene3078	3.1e-39	168.7	Sphingobacteriia			1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IQYU@117747,4NEFB@976,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.18_02563	1121904.ARBP01000007_gene2906	8.7e-22	110.5	Bacteroidetes	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564		ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018			R05712	RC00176	ko00000,ko02000	9.B.14.1			Bacteria	4NGHU@976,COG3088@1,COG3088@2	NA|NA|NA	O	Psort location CytoplasmicMembrane, score
MAG.T21.18_02564	1122931.AUAE01000001_gene770	2.8e-79	302.4	Porphyromonadaceae	batA			ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	22XC0@171551,2FNXM@200643,4NDUC@976,COG2304@1,COG2304@2	NA|NA|NA	S	Von Willebrand factor type A domain
MAG.T21.18_02565	1408473.JHXO01000004_gene63	1.2e-75	290.4	Bacteroidia	batB			ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	2FN4B@200643,4NF7Y@976,COG2304@1,COG2304@2	NA|NA|NA	S	Von Willebrand factor type A domain
MAG.T21.18_02568	714943.Mucpa_6112	2.3e-86	326.6	Sphingobacteriia													Bacteria	1IR9Z@117747,4NERG@976,COG0457@1,COG0457@2	NA|NA|NA	S	Oxygen tolerance
MAG.T21.18_02569	1501391.LG35_05925	3.6e-28	132.1	Rikenellaceae													Bacteria	22V8H@171550,2FP54@200643,4NF5V@976,COG0457@1,COG0457@2	NA|NA|NA	T	Tetratricopeptide repeat
MAG.T21.18_02570	1121373.KB903627_gene2950	1.5e-80	308.9	Cytophagia													Bacteria	47NB2@768503,4NIJA@976,COG2133@1,COG2133@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.18_02574	700598.Niako_1583	2.5e-153	548.5	Sphingobacteriia	atoB		2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147			iJN746.PP_2215	Bacteria	1IP5F@117747,4NE3Q@976,COG0183@1,COG0183@2	NA|NA|NA	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MAG.T21.18_02575	926562.Oweho_1079	1.6e-55	223.0	Cryomorphaceae	ykfC		3.4.14.13	ko:K20742,ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	1HX9E@117743,2PAUH@246874,4NE2T@976,COG0791@1,COG0791@2	NA|NA|NA	M	NlpC/P60 family
MAG.T21.18_02577	1237149.C900_01101	6.1e-191	674.5	Cytophagia													Bacteria	47K3W@768503,4PKVH@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.18_02578	700598.Niako_4597	8.9e-26	125.6	Sphingobacteriia													Bacteria	1INXJ@117747,4NIGK@976,COG3078@1,COG3078@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.18_02579	1237149.C900_01099	9.6e-34	151.0	Cytophagia													Bacteria	47PEK@768503,4NMA2@976,COG3712@1,COG3712@2	NA|NA|NA	PT	Domain of unknown function (DUF4974)
MAG.T21.18_02580	1408473.JHXO01000007_gene954	1.8e-32	146.0	Bacteroidia				ko:K03088					ko00000,ko03021				Bacteria	2FNRK@200643,4NNBY@976,COG1595@1,COG1595@2	NA|NA|NA	K	RNA polymerase sigma-70 factor
MAG.T21.18_02581	755732.Fluta_3674	3.2e-109	404.1	Bacteroidetes			3.2.1.136,3.4.21.50	ko:K01337,ko:K15924					ko00000,ko01000,ko01002		GH5		Bacteria	4NNUN@976,COG1520@1,COG1520@2,COG2133@1,COG2133@2,COG3291@1,COG3291@2	NA|NA|NA	P	domain protein
MAG.T21.18_02583	153721.MYP_3250	9.4e-14	84.0	Bacteroidetes	amyB3												Bacteria	4NY26@976,COG4733@1,COG4733@2	NA|NA|NA	S	SPTR Putative
MAG.T21.18_02584	1401067.HMPREF0872_04270	3.8e-09	67.8	Firmicutes													Bacteria	1VN9X@1239,2DNMU@1,32Y5V@2	NA|NA|NA		
MAG.T21.18_02585	1550091.JROE01000002_gene514	2.2e-09	69.7	Bacteroidetes													Bacteria	4NQGR@976,COG4552@1,COG4552@2	NA|NA|NA	S	Acetyltransferase (GNAT) family
MAG.T21.18_02587	925409.KI911562_gene1505	1e-31	143.7	Bacteroidetes													Bacteria	4NN4D@976,COG2197@1,COG2197@2	NA|NA|NA	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.18_02588	700598.Niako_3302	2.6e-14	87.8	Bacteria													Bacteria	COG1520@1,COG1520@2	NA|NA|NA	S	amino acid activation for nonribosomal peptide biosynthetic process
MAG.T21.18_02589	1121904.ARBP01000063_gene2836	5.6e-17	94.0	Cytophagia													Bacteria	47JQ1@768503,4NHCZ@976,COG0457@1,COG0457@2,COG4995@1,COG4995@2	NA|NA|NA	S	CHAT domain
MAG.T21.18_02593	906968.Trebr_0433	5e-71	275.8	Spirochaetes													Bacteria	2J6HA@203691,COG2114@1,COG2114@2	NA|NA|NA	T	Guanylate cyclase
MAG.T21.18_02594	44251.PDUR_01350	8.7e-26	124.0	Paenibacillaceae													Bacteria	1VJB0@1239,26ZHW@186822,2C6ZK@1,32VSY@2,4HZ34@91061	NA|NA|NA		
MAG.T21.18_02595	1032480.MLP_36630	3.6e-30	139.4	Propionibacteriales				ko:K09703					ko00000				Bacteria	2HJF5@201174,4DSA5@85009,COG3535@1,COG3535@2	NA|NA|NA	S	Protein of unknown function (DUF917)
MAG.T21.18_02596	1296416.JACB01000003_gene685	1.8e-19	102.4	Aquimarina													Bacteria	1II1C@117743,2ENSF@1,2YKH3@290174,33GDN@2,4P5JA@976	NA|NA|NA		
MAG.T21.18_02597	1137281.D778_02741	2.5e-120	438.3	Flavobacteriia				ko:K07045					ko00000				Bacteria	1HXKV@117743,4NJP9@976,COG2159@1,COG2159@2	NA|NA|NA	S	Amidohydrolase
MAG.T21.18_02598	760192.Halhy_0843	2.9e-137	495.7	Sphingobacteriia													Bacteria	1IRYN@117747,4NF52@976,COG0471@1,COG0471@2	NA|NA|NA	P	Sodium:sulfate symporter transmembrane region
MAG.T21.18_02600	471854.Dfer_1325	4.5e-48	198.4	Cytophagia													Bacteria	47PZR@768503,4NGXX@976,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
MAG.T21.18_02601	1358423.N180_17025	8.8e-17	94.0	Sphingobacteriia													Bacteria	1ISD0@117747,294ZR@1,2ZSCK@2,4NNYY@976	NA|NA|NA	S	COG NOG27188 non supervised orthologous group
MAG.T21.18_02602	760192.Halhy_1552	4.4e-49	201.4	Bacteroidetes				ko:K15256					ko00000,ko01000,ko03016				Bacteria	4PNE0@976,COG0500@1,COG0500@2	NA|NA|NA	Q	Methyltransferase domain
MAG.T21.18_02603	1089547.KB913013_gene816	2.2e-39	170.2	Cytophagia													Bacteria	47NK0@768503,4NGEP@976,COG2885@1,COG2885@2,COG3291@1,COG3291@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.18_02604	153721.MYP_925	2.3e-20	105.9	Cytophagia													Bacteria	28Q4C@1,2ZCMM@2,47PKB@768503,4NM6S@976	NA|NA|NA		
MAG.T21.18_02607	755732.Fluta_2360	1.3e-14	87.4	Flavobacteriia													Bacteria	1I1KX@117743,4NI2T@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller
MAG.T21.18_02608	1408473.JHXO01000003_gene2586	1e-13	84.0	Bacteroidia													Bacteria	2DRHS@1,2FXQ0@200643,33BTF@2,4NXHD@976	NA|NA|NA		
MAG.T21.18_02609	1121896.JMLU01000011_gene1531	1.7e-49	202.2	Flavobacterium	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377	Bacteria	1HWP2@117743,2NSQP@237,4NEWT@976,COG0504@1,COG0504@2	NA|NA|NA	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAG.T21.18_02613	1121895.Q765_13805	2.3e-15	89.7	Flavobacterium													Bacteria	1I6VF@117743,2EPIV@1,2NZSN@237,33H5H@2,4NXHG@976	NA|NA|NA	S	RES domain
MAG.T21.18_02614	886379.AEWI01000009_gene707	6.4e-127	461.5	Marinilabiliaceae	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150		ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	2FN3A@200643,3XJ5F@558415,4NESJ@976,COG0706@1,COG0706@2	NA|NA|NA	U	YidC periplasmic domain
MAG.T21.18_02615	1237149.C900_04437	3.9e-13	81.6	Bacteria			2.8.1.1,2.8.1.2	ko:K01011,ko:K06867	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122		R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000				Bacteria	COG0666@1,COG0666@2	NA|NA|NA	G	response to abiotic stimulus
MAG.T21.18_02616	1279009.ADICEAN_01785	7.8e-212	743.8	Cytophagia	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575											Bacteria	47MF3@768503,4NEAK@976,COG3591@1,COG3591@2	NA|NA|NA	E	Peptidase S46
MAG.T21.18_02617	1484460.JSWG01000012_gene1461	2.8e-52	213.0	Flavobacteriia													Bacteria	1HZVF@117743,4NIK7@976,COG4872@1,COG4872@2	NA|NA|NA	S	Predicted membrane protein (DUF2157)
MAG.T21.18_02618	1406840.Q763_04430	1.9e-25	122.9	Flavobacterium													Bacteria	1I3Q6@117743,2NZ2B@237,4NQB4@976,COG4929@1,COG4929@2	NA|NA|NA	S	GDYXXLXY protein
MAG.T21.18_02619	869213.JCM21142_104477	3.8e-26	125.6	Cytophagia	cysZ	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600		ko:K06203					ko00000			iJR904.b2413,iYL1228.KPN_02760	Bacteria	47SCF@768503,4NHXY@976,COG2981@1,COG2981@2	NA|NA|NA	E	Etoposide-induced protein 2.4 (EI24)
MAG.T21.18_02620	153721.MYP_3395	8.5e-161	573.5	Cytophagia	purB	GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000			iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510	Bacteria	47KAQ@768503,4NFY8@976,COG0015@1,COG0015@2	NA|NA|NA	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAG.T21.18_02621	1004149.AFOE01000055_gene126	1.4e-50	206.5	Flavobacteriia	sanA			ko:K03748					ko00000				Bacteria	1I1DV@117743,4NNQS@976,COG2949@1,COG2949@2	NA|NA|NA	S	membrane
MAG.T21.18_02622	1379698.RBG1_1C00001G0743	1.4e-17	96.3	unclassified Bacteria	dinB			ko:K07552					ko00000,ko02000	2.A.1.2			Bacteria	2NRHG@2323,COG2318@1,COG2318@2	NA|NA|NA	S	DinB superfamily
MAG.T21.18_02623	755732.Fluta_0691	3.5e-25	121.7	Cryomorphaceae													Bacteria	1IFSM@117743,2A21C@1,2PBPD@246874,30QBC@2,4PGY1@976	NA|NA|NA		
MAG.T21.18_02624	755732.Fluta_4031	2.5e-156	558.5	Cryomorphaceae	lhgO		1.1.99.2	ko:K00109,ko:K15736	ko00650,map00650		R03534	RC00031	ko00000,ko00001,ko01000				Bacteria	1HZQJ@117743,2PACG@246874,4NE0B@976,COG0579@1,COG0579@2	NA|NA|NA	S	FAD dependent oxidoreductase
MAG.T21.18_02625	1185876.BN8_02817	3e-113	415.6	Cytophagia	yxiO			ko:K06902	ko04138,map04138				ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1			Bacteria	47JQM@768503,4NEKI@976,COG2270@1,COG2270@2	NA|NA|NA	S	PFAM Vacuole effluxer Atg22 like
MAG.T21.18_02626	143224.JQMD01000002_gene2736	1.4e-22	112.5	Flavobacteriia			2.6.1.102	ko:K13010	ko00520,map00520		R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007				Bacteria	1I4HI@117743,4NVFZ@976,COG0399@1,COG0399@2	NA|NA|NA	M	23S rRNA-intervening sequence protein
MAG.T21.18_02627	1408433.JHXV01000017_gene1609	7.2e-60	238.0	Cryomorphaceae													Bacteria	1HXSH@117743,2PBE6@246874,4NKCW@976,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA family
MAG.T21.18_02628	1237149.C900_00006	6.3e-22	111.3	Cytophagia													Bacteria	47QK5@768503,4NR9K@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.18_02629	1120966.AUBU01000003_gene1641	0.0	1196.8	Cytophagia	acnA		4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47KF9@768503,4NDZT@976,COG1048@1,COG1048@2	NA|NA|NA	C	aconitate hydratase
MAG.T21.18_02630	153721.MYP_294	3.5e-12	79.0	Bacteria													Bacteria	2DQAI@1,335NH@2	NA|NA|NA		
MAG.T21.18_02631	1123008.KB905694_gene1735	2e-39	168.7	Porphyromonadaceae	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02939	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	22XP0@171551,2FSTU@200643,4NNRP@976,COG0359@1,COG0359@2	NA|NA|NA	J	binds to the 23S rRNA
MAG.T21.18_02633	746697.Aeqsu_1753	1.5e-06	60.5	Flavobacteriia				ko:K15977					ko00000				Bacteria	1I0YP@117743,4NK73@976,COG2259@1,COG2259@2	NA|NA|NA	S	Doxx family
MAG.T21.18_02635	1519464.HY22_14405	2.1e-13	81.6	Bacteria				ko:K03286					ko00000,ko02000	1.B.6			Bacteria	COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.18_02636	1242864.D187_001577	3.9e-68	265.8	Proteobacteria													Bacteria	1R5QH@1224,COG3420@1,COG3420@2	NA|NA|NA	P	lipolytic protein G-D-S-L family
MAG.T21.18_02637	391596.PBAL39_16324	9.1e-107	394.0	Sphingobacteriia	nhaA			ko:K03313					ko00000,ko02000	2.A.33.1			Bacteria	1INUT@117747,4NFC4@976,COG3004@1,COG3004@2	NA|NA|NA	P	) H( ) antiporter that extrudes sodium in exchange for external protons
MAG.T21.18_02638	742766.HMPREF9455_02117	2.5e-12	77.8	Porphyromonadaceae													Bacteria	22Y31@171551,2FTXH@200643,4NQB5@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.18_02640	742766.HMPREF9455_02117	5.8e-35	154.1	Porphyromonadaceae													Bacteria	22Y31@171551,2FTXH@200643,4NQB5@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.18_02642	1453505.JASY01000001_gene3542	4.4e-80	305.8	Flavobacterium			4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYQY@117743,2NUIW@237,4NEVN@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2	NA|NA|NA	T	Adenylyl- / guanylyl cyclase, catalytic domain
MAG.T21.18_02643	1237149.C900_00129	6.8e-304	1049.7	Cytophagia													Bacteria	47KZ5@768503,4NDYB@976,COG3537@1,COG3537@2	NA|NA|NA	G	PFAM Glycosyl Hydrolase
MAG.T21.18_02644	929562.Emtol_0648	1.9e-97	362.5	Cytophagia	yhhW_1			ko:K06911					ko00000				Bacteria	47MY1@768503,4NFZD@976,COG1741@1,COG1741@2	NA|NA|NA	S	Belongs to the pirin family
MAG.T21.18_02645	1356852.N008_05645	4.6e-42	179.1	Cytophagia													Bacteria	47NWE@768503,4NH6T@976,COG2133@1,COG2133@2	NA|NA|NA	CG	Glucose / Sorbosone dehydrogenase
MAG.T21.18_02646	861299.J421_2010	4.1e-54	218.4	Bacteria	vdlC												Bacteria	COG4221@1,COG4221@2	NA|NA|NA	IQ	oxidoreductase activity
MAG.T21.18_02647	468059.AUHA01000002_gene562	3.3e-94	351.7	Sphingobacteriia	yneE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K08994					ko00000,ko02000	1.A.46.2			Bacteria	1IQHC@117747,4NEB1@976,COG3781@1,COG3781@2	NA|NA|NA	S	COGs COG3781 membrane protein
MAG.T21.18_02649	1341181.FLJC2902T_05060	2e-14	87.4	Flavobacterium													Bacteria	1IKDI@117743,2P0DY@237,4PKPT@976,COG3386@1,COG3386@2	NA|NA|NA	G	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02650	984262.SGRA_2219	9.3e-53	214.2	Bacteroidetes													Bacteria	4NKAQ@976,COG2968@1,COG2968@2	NA|NA|NA	S	Protein of unknown function (DUF541)
MAG.T21.18_02651	869213.JCM21142_93814	4.3e-151	541.2	Cytophagia	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007			iYO844.BSU40340	Bacteria	47K80@768503,4NE93@976,COG4992@1,COG4992@2	NA|NA|NA	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.18_02652	926562.Oweho_1575	7.5e-97	360.9	Cryomorphaceae	glmU		2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWW0@117743,2PA85@246874,4NDZP@976,COG1207@1,COG1207@2	NA|NA|NA	M	Sugar nucleotidyl transferase
MAG.T21.18_02653	929556.Solca_4126	1.1e-166	592.8	Sphingobacteriia	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535		ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147				Bacteria	1INP2@117747,4NDZM@976,COG0459@1,COG0459@2	NA|NA|NA	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAG.T21.18_02654	1237149.C900_03131	9e-23	115.9	Cytophagia													Bacteria	47UW8@768503,4NUV8@976,COG2353@1,COG2353@2	NA|NA|NA	S	YceI-like domain
MAG.T21.18_02656	926562.Oweho_1042	8.5e-43	182.2	Cryomorphaceae													Bacteria	1HX4T@117743,2PC63@246874,4NI65@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_02657	1122917.KB899662_gene2118	1e-29	136.3	Paenibacillaceae	yuxK												Bacteria	1V7DJ@1239,26YKY@186822,4HIUD@91061,COG3011@1,COG3011@2	NA|NA|NA	S	Thiol-disulfide oxidoreductase DCC
MAG.T21.18_02658	1211813.CAPH01000013_gene553	1.7e-96	359.4	Rikenellaceae	natA			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	22V5K@171550,2FMK3@200643,4NEJE@976,COG4152@1,COG4152@2	NA|NA|NA	S	Domain of unknown function (DUF4162)
MAG.T21.18_02659	1123278.KB893388_gene5725	2.4e-83	316.2	Cytophagia	natB			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	47JCK@768503,4NFSZ@976,COG1668@1,COG1668@2	NA|NA|NA	CP	COGs COG1668 ABC-type Na efflux pump permease component
MAG.T21.18_02660	926562.Oweho_3041	4.2e-55	221.9	Cryomorphaceae	gppA-2		3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	1IMPX@117743,2PAVM@246874,4NH03@976,COG0248@1,COG0248@2	NA|NA|NA	FP	Ppx/GppA phosphatase family
MAG.T21.18_02661	1123400.KB904752_gene845	1.5e-27	131.3	Proteobacteria													Bacteria	1QWWH@1224,COG2834@1,COG2834@2,COG3420@1,COG3420@2	NA|NA|NA	P	Beta-L-arabinofuranosidase, GH127
MAG.T21.18_02662	869213.JCM21142_93635	7.1e-140	503.8	Cytophagia	ntrX												Bacteria	47JKI@768503,4NE89@976,COG2204@1,COG2204@2	NA|NA|NA	T	CheY-like receiver AAA-type ATPase and DNA-binding domains
MAG.T21.18_02663	911239.CF149_09437	6e-20	105.5	Gammaproteobacteria	IV02_13120												Bacteria	1NYS1@1224,1RPR2@1236,28IQ1@1,2Z8PV@2	NA|NA|NA		
MAG.T21.18_02664	177439.DP2559	4e-19	101.7	Desulfobacterales													Bacteria	1Q4QD@1224,2AJFK@1,2MP3H@213118,2WYIU@28221,31A1X@2,4326M@68525	NA|NA|NA		
MAG.T21.18_02665	1089550.ATTH01000001_gene2193	1e-72	282.0	Bacteria				ko:K03546					ko00000,ko03400				Bacteria	COG0419@1,COG0419@2	NA|NA|NA	L	ATPase involved in DNA repair
MAG.T21.18_02668	411477.PARMER_01030	2.1e-85	322.8	Porphyromonadaceae													Bacteria	22XBH@171551,2FMJE@200643,4NFMB@976,COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.18_02669	694427.Palpr_1191	5.8e-91	341.3	Bacteroidia													Bacteria	2FSCQ@200643,4NH7K@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.18_02670	485918.Cpin_6574	2.7e-103	382.1	Sphingobacteriia	murB		1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100		R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011				Bacteria	1IQP9@117747,4NE78@976,COG0812@1,COG0812@2	NA|NA|NA	M	Cell wall formation
MAG.T21.18_02671	504487.JCM19302_3837	4.8e-74	285.0	Flavobacteriia			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	1HXUF@117743,4NE4P@976,COG1858@1,COG1858@2	NA|NA|NA	C	cytochrome C peroxidase
MAG.T21.18_02672	1197477.IA57_06430	1.4e-73	283.5	Flavobacteriia			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	1HXUF@117743,4NE4P@976,COG1858@1,COG1858@2	NA|NA|NA	C	cytochrome C peroxidase
MAG.T21.18_02673	1356852.N008_03025	1.8e-173	616.3	Cytophagia	ptpA		3.4.14.12,3.4.14.5	ko:K01278,ko:K06889,ko:K18574	ko04974,map04974				ko00000,ko00001,ko01000,ko01002,ko04090,ko04147				Bacteria	47P67@768503,4NF7I@976,COG1506@1,COG1506@2	NA|NA|NA	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MAG.T21.18_02675	945713.IALB_0147	1.2e-73	283.9	Bacteria			3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000,ko01002				Bacteria	COG2234@1,COG2234@2,COG4412@1,COG4412@2	NA|NA|NA	S	peptidase activity, acting on L-amino acid peptides
MAG.T21.18_02676	1122176.KB903546_gene1028	5.8e-142	511.5	Bacteria	manA5		3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024		R01332	RC00467	ko00000,ko00001,ko01000,ko04147		GH26,GH29		Bacteria	COG2133@1,COG2133@2	NA|NA|NA	G	pyrroloquinoline quinone binding
MAG.T21.18_02677	1203611.KB894552_gene1080	1.9e-26	125.9	Rikenellaceae													Bacteria	22UI7@171550,2DEYG@1,2FTAK@200643,2ZPSM@2,4NNJW@976	NA|NA|NA	S	COG NOG14473 non supervised orthologous group
MAG.T21.18_02678	755732.Fluta_0650	1.9e-162	578.9	Cryomorphaceae													Bacteria	1HXI3@117743,2CD20@1,2PAEU@246874,2Z7SQ@2,4NEQ1@976	NA|NA|NA		
MAG.T21.18_02679	1408433.JHXV01000002_gene467	2.7e-163	582.0	Cryomorphaceae	dnaB		3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112				ko00000,ko00001,ko01000,ko03032				Bacteria	1HWS1@117743,2PAKC@246874,4NF8P@976,COG0305@1,COG0305@2	NA|NA|NA	L	Participates in initiation and elongation during chromosome replication
MAG.T21.18_02681	926562.Oweho_1753	6.9e-128	463.8	Cryomorphaceae	accA	GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000			iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN678.accA,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197	Bacteria	1HXWT@117743,2PAAG@246874,4NEVU@976,COG0825@1,COG0825@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MAG.T21.18_02682	641524.ADICYQ_5674	2.2e-61	242.7	Cytophagia	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.1.1.182,2.7.1.148	ko:K00919,ko:K02528,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634,R10716	RC00002,RC00003,RC01439,RC03257	ko00000,ko00001,ko00002,ko01000,ko02000,ko03009	3.A.1.29		iYO844.BSU00460	Bacteria	47JG4@768503,4NGFC@976,COG1947@1,COG1947@2	NA|NA|NA	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MAG.T21.18_02683	926549.KI421517_gene3596	3.6e-15	89.7	Cytophagia													Bacteria	47JZP@768503,4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.18_02685	1453500.AT05_07745	1.7e-86	325.5	Flavobacteriia	atpD		3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1			Bacteria	1HWM2@117743,4NF1Q@976,COG0055@1,COG0055@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAG.T21.18_02686	1121472.AQWN01000008_gene2005	4.5e-14	83.6	Peptococcaceae	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	Bacteria	1VA89@1239,24ND7@186801,2629N@186807,COG0355@1,COG0355@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane
MAG.T21.18_02687	1121897.AUGO01000005_gene101	5.1e-28	134.4	Flavobacterium		GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944											Bacteria	1IJYE@117743,2P0PK@237,4PMS8@976,COG3391@1,COG3391@2,COG4412@1,COG4412@2	NA|NA|NA	S	Fibronectin type 3 domain
MAG.T21.18_02688	1492737.FEM08_17900	1.7e-09	69.3	Flavobacterium	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1HY4X@117743,2NUE4@237,4NFTP@976,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
MAG.T21.18_02689	929556.Solca_2077	1.5e-294	1018.8	Sphingobacteriia	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1INPU@117747,4NFHW@976,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAG.T21.18_02690	1453500.AT05_06130	5.9e-92	344.4	Flavobacteriia				ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	1HX46@117743,4NGHH@976,COG0739@1,COG0739@2	NA|NA|NA	M	Peptidase, M23
MAG.T21.18_02691	926562.Oweho_1873	6.9e-20	103.6	Cryomorphaceae	ycgE			ko:K19591,ko:K22491		M00769			ko00000,ko00002,ko01504,ko03000				Bacteria	1I2UP@117743,2PB5G@246874,4NSBD@976,COG0789@1,COG0789@2	NA|NA|NA	K	helix_turn_helix, mercury resistance
MAG.T21.18_02692	319225.Plut_1793	2.2e-32	146.4	Bacteria													Bacteria	COG4123@1,COG4123@2	NA|NA|NA	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MAG.T21.18_02693	1089547.KB913013_gene3562	3.1e-133	481.5	Cytophagia	hldD		5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	47KEK@768503,4NIZG@976,COG0451@1,COG0451@2	NA|NA|NA	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose
MAG.T21.18_02694	207559.Dde_2886	1.6e-37	163.3	Desulfovibrionales													Bacteria	1RF4D@1224,2MDUX@213115,2X9I3@28221,42UGX@68525,COG0438@1,COG0438@2	NA|NA|NA	H	TIGRFAM methyltransferase FkbM
MAG.T21.18_02695	319225.Plut_1793	8.3e-32	144.4	Bacteria													Bacteria	COG4123@1,COG4123@2	NA|NA|NA	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MAG.T21.18_02696	1358423.N180_16770	7.8e-41	173.3	Sphingobacteriia			4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1ISCG@117747,4NNY0@976,COG0720@1,COG0720@2	NA|NA|NA	H	6-pyruvoyl tetrahydrobiopterin synthase
MAG.T21.18_02697	1122621.ATZA01000010_gene143	2.6e-83	315.1	Sphingobacteriia	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPBD@117747,4NFC2@976,COG0302@1,COG0302@2	NA|NA|NA	H	GTP cyclohydrolase
MAG.T21.18_02698	468059.AUHA01000002_gene313	4.3e-47	194.9	Sphingobacteriia	ybhL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06890					ko00000				Bacteria	1ISUF@117747,4NR2U@976,COG0670@1,COG0670@2	NA|NA|NA	S	Inhibitor of apoptosis-promoting Bax1
MAG.T21.18_02699	1410613.JNKF01000014_gene2190	4.9e-109	401.0	Bacteroidia	fabD		2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	2FM9P@200643,4NE1D@976,COG0331@1,COG0331@2	NA|NA|NA	I	malonyl CoA-acyl carrier protein transacylase
MAG.T21.18_02702	1408433.JHXV01000024_gene1451	4.6e-59	235.0	Cryomorphaceae													Bacteria	1I2CE@117743,2PBPQ@246874,4NMUT@976,COG4464@1,COG4464@2	NA|NA|NA	GM	COG4464 Capsular polysaccharide biosynthesis protein
MAG.T21.18_02703	679935.Alfi_1224	1.4e-51	209.1	Rikenellaceae	kbl		2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	22U6I@171550,2FNXA@200643,4NFRY@976,COG0156@1,COG0156@2	NA|NA|NA	E	Aminotransferase class I and II
MAG.T21.18_02704	1150600.ADIARSV_1602	1.4e-59	236.5	Sphingobacteriia	truA	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.12	ko:K06173					ko00000,ko01000,ko03016				Bacteria	1IPUQ@117747,4NFDC@976,COG0101@1,COG0101@2	NA|NA|NA	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAG.T21.18_02705	762903.Pedsa_2486	1.4e-179	636.3	Sphingobacteriia	MdlB			ko:K06147,ko:K18890	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21			Bacteria	1IQFU@117747,4NEAG@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter
MAG.T21.18_02706	1408433.JHXV01000022_gene3138	2.2e-183	650.2	Flavobacteriia													Bacteria	1I7ZV@117743,4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	S	PFAM PKD domain
MAG.T21.18_02707	1453500.AT05_00970	7.3e-177	628.2	Bacteroidetes													Bacteria	4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	U	PFAM PKD domain
MAG.T21.18_02708	1408473.JHXO01000004_gene131	0.0	1124.8	Bacteroidia	uvrA2			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2FNFZ@200643,4NEHM@976,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAG.T21.18_02709	1250006.JHZZ01000001_gene2876	1.4e-62	246.1	Polaribacter	rpoE			ko:K03088					ko00000,ko03021				Bacteria	1HX2Z@117743,3VVZ7@52959,4NF93@976,COG1595@1,COG1595@2	NA|NA|NA	K	ECF sigma factor
MAG.T21.18_02711	700598.Niako_5173	5.2e-97	361.3	Sphingobacteriia			1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020				ko00000,ko00001,ko01000,ko01004				Bacteria	1IZDH@117747,4NNB2@976,COG3239@1,COG3239@2	NA|NA|NA	I	PFAM Fatty acid desaturase
MAG.T21.18_02712	485918.Cpin_2595	2.6e-89	335.5	Sphingobacteriia	waaM		2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IRHE@117747,4NGQU@976,COG1560@1,COG1560@2	NA|NA|NA	M	PFAM Bacterial lipid A biosynthesis acyltransferase
MAG.T21.18_02713	1107311.Q767_04705	1.3e-76	292.7	Flavobacterium	nth		4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1HX6E@117743,2NTCV@237,4NFF3@976,COG0177@1,COG0177@2	NA|NA|NA	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAG.T21.18_02714	1034807.FBFL15_0414	7.6e-54	217.2	Flavobacteriia													Bacteria	1IAZQ@117743,2C3W4@1,32ZTW@2,4NWCI@976	NA|NA|NA		
MAG.T21.18_02715	1286632.P278_20050	1.6e-13	82.8	Flavobacteriia													Bacteria	1I2EY@117743,2AE6H@1,3140B@2,4NSDV@976	NA|NA|NA		
MAG.T21.18_02716	313598.MED152_05710	3.5e-18	97.8	Polaribacter													Bacteria	1IGJJ@117743,29X26@1,30IQM@2,3VWW1@52959,4P9J9@976	NA|NA|NA	S	23S rRNA-intervening sequence protein
MAG.T21.18_02718	521674.Plim_3466	1.1e-35	155.6	Planctomycetes	lepA			ko:K03596	ko05134,map05134				ko00000,ko00001				Bacteria	2IXI5@203682,COG0481@1,COG0481@2	NA|NA|NA	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAG.T21.18_02719	1121904.ARBP01000007_gene3099	7.1e-30	138.3	Cytophagia	CP_1117		2.1.1.294,2.7.1.181	ko:K18827			R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005				Bacteria	47WA7@768503,4NMT7@976,COG4372@1,COG4372@2	NA|NA|NA	S	Transposase
MAG.T21.18_02723	504472.Slin_0750	4.2e-22	110.9	Cytophagia													Bacteria	47R2J@768503,4NTZU@976,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulator receiver domain
MAG.T21.18_02724	1237149.C900_05339	3.9e-129	468.4	Cytophagia				ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499			ko00000,ko00001,ko00002,ko02022				Bacteria	47N6B@768503,4NE89@976,COG2204@1,COG2204@2	NA|NA|NA	T	two component, sigma54 specific, transcriptional regulator, Fis family
MAG.T21.18_02725	1089547.KB913013_gene1733	1.6e-47	197.6	Cytophagia			2.7.13.3	ko:K14986	ko02020,map02020	M00524			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	47MZF@768503,4NFFM@976,COG0784@1,COG0784@2,COG5000@1,COG5000@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
MAG.T21.18_02727	926562.Oweho_3360	2e-31	143.3	Bacteroidetes													Bacteria	4PM2M@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_02728	929556.Solca_0272	1.1e-104	386.7	Sphingobacteriia	gpsA		1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110		R00842,R00844	RC00029	ko00000,ko00001,ko01000				Bacteria	1IQF4@117747,4NF4R@976,COG0240@1,COG0240@2	NA|NA|NA	I	Glycerol-3-phosphate dehydrogenase
MAG.T21.18_02729	926562.Oweho_2547	3.7e-126	458.8	Cryomorphaceae													Bacteria	1HXXH@117743,2PBDE@246874,4NFZR@976,COG0265@1,COG0265@2,COG2234@1,COG2234@2	NA|NA|NA	O	Peptidase family M28
MAG.T21.18_02730	338963.Pcar_1365	3.5e-11	73.9	Deltaproteobacteria													Bacteria	1P7A9@1224,2ESM6@1,2WXY5@28221,33K5R@2,4326F@68525	NA|NA|NA	S	Protein of unknown function (DUF1232)
MAG.T21.18_02731	926549.KI421517_gene1746	5.5e-46	192.6	Cytophagia			5.2.1.8	ko:K01802,ko:K03768					ko00000,ko01000,ko03110				Bacteria	47MDR@768503,4PM5K@976,COG0652@1,COG0652@2,COG1413@1,COG1413@2	NA|NA|NA	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
MAG.T21.18_02732	1250278.JQNQ01000001_gene3045	3.7e-311	1073.9	Flavobacteriia	yaaO		4.1.1.19	ko:K01584,ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	1I0X3@117743,4NHSM@976,COG1982@1,COG1982@2	NA|NA|NA	E	PFAM Orn Lys Arg decarboxylase, C-terminal domain
MAG.T21.18_02733	616991.JPOO01000001_gene4614	6e-39	166.8	Flavobacteriia													Bacteria	1I2AG@117743,2AY99@1,31QBJ@2,4NNSA@976	NA|NA|NA		
MAG.T21.18_02734	1356852.N008_06520	1.2e-10	75.5	Cytophagia				ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	47YR2@768503,4NDZC@976,COG3291@1,COG3291@2	NA|NA|NA	S	Pkd domain containing protein
MAG.T21.18_02737	521674.Plim_1242	1.6e-09	68.9	Planctomycetes	agmK		1.8.1.8,1.8.1.9	ko:K00384,ko:K03671,ko:K03672,ko:K12574	ko00450,ko03018,ko04621,ko05418,map00450,map03018,map04621,map05418		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03019,ko03110				Bacteria	2J0WY@203682,COG3118@1,COG3118@2	NA|NA|NA	O	belongs to the thioredoxin family
MAG.T21.18_02738	1408473.JHXO01000009_gene3352	2.2e-130	473.4	Bacteroidia													Bacteria	2FM9F@200643,4NFWD@976,COG1452@1,COG1452@2	NA|NA|NA	M	Psort location OuterMembrane, score
MAG.T21.18_02739	926562.Oweho_0210	1.3e-82	313.5	Cryomorphaceae	amiA		3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036				Bacteria	1HX7G@117743,2PAR3@246874,4NGKC@976,COG0860@1,COG0860@2	NA|NA|NA	M	Ami_3
MAG.T21.18_02740	504487.JCM19302_2410	2.1e-47	196.4	Flavobacteriia	ttg2C			ko:K02067	ko02010,map02010	M00210,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1HXN5@117743,4NHT9@976,COG1463@1,COG1463@2	NA|NA|NA	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component
MAG.T21.18_02741	929556.Solca_0345	4.7e-148	531.2	Sphingobacteriia													Bacteria	1IQ7C@117747,4NF3K@976,COG1150@1,COG1150@2	NA|NA|NA	C	Fe-S oxidoreductase
MAG.T21.18_02742	313590.MED134_03739	3e-118	431.4	Dokdonia													Bacteria	1HXAY@117743,37DR5@326319,4NDZS@976,COG0247@1,COG0247@2	NA|NA|NA	C	Cysteine-rich domain
MAG.T21.18_02743	1123037.AUDE01000032_gene2255	6e-26	124.0	Flavobacteriia													Bacteria	1HYDM@117743,28NRS@1,2ZBQZ@2,4NMM5@976	NA|NA|NA		
MAG.T21.18_02744	926562.Oweho_0344	2e-86	326.6	Cryomorphaceae	lptA			ko:K09774					ko00000,ko02000	1.B.42.1			Bacteria	1IKDV@117743,2PAQU@246874,4PKT4@976,COG1934@1,COG1934@2	NA|NA|NA	S	OstA-like protein
MAG.T21.18_02745	1349822.NSB1T_08400	5.7e-23	114.4	Porphyromonadaceae													Bacteria	22XT2@171551,2CGY7@1,2FPIK@200643,2ZGS8@2,4NREX@976	NA|NA|NA	S	Domain of unknown function (DUF4924)
MAG.T21.18_02746	700598.Niako_4930	7.9e-08	64.3	Sphingobacteriia				ko:K06142					ko00000				Bacteria	1IU3T@117747,4NQGG@976,COG2825@1,COG2825@2	NA|NA|NA	M	Outer membrane chaperone Skp
MAG.T21.18_02747	102125.Xen7305DRAFT_00016350	3e-16	94.0	Pleurocapsales				ko:K03641					ko00000,ko02000	2.C.1.2			Bacteria	1GJ0J@1117,3VIZ2@52604,COG0823@1,COG0823@2	NA|NA|NA	QU	calcium- and calmodulin-responsive adenylate cyclase activity
MAG.T21.18_02749	926562.Oweho_1183	7.3e-93	347.1	Cryomorphaceae	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100		R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036			iJN678.sll1005	Bacteria	1HWKT@117743,2PAC4@246874,4NEA3@976,COG1694@1,COG3956@2	NA|NA|NA	S	MazG nucleotide pyrophosphohydrolase domain
MAG.T21.18_02753	1239415.CM001837_gene2104	4.8e-10	70.9	Dokdonia													Bacteria	1I5TJ@117743,2DNRU@1,32YUJ@2,37FHZ@326319,4NVE3@976	NA|NA|NA		
MAG.T21.18_02754	517417.Cpar_0379	4.2e-09	69.3	Bacteria													Bacteria	28IAZ@1,2Z8DG@2	NA|NA|NA	S	DGQHR domain
MAG.T21.18_02755	755732.Fluta_2885	7.3e-26	126.3	Cryomorphaceae			3.4.21.50	ko:K01337					ko00000,ko01000,ko01002				Bacteria	1IGQE@117743,2PBJ6@246874,4PI0H@976,COG3291@1,COG3291@2	NA|NA|NA	S	PKD domain
MAG.T21.18_02756	926562.Oweho_0540	4.3e-24	118.6	Bacteria													Bacteria	COG0589@1,COG0589@2	NA|NA|NA	T	AMP binding
MAG.T21.18_02757	1408433.JHXV01000005_gene2349	1.8e-145	523.5	Cryomorphaceae													Bacteria	1HZ43@117743,2PBIN@246874,4NDUD@976,COG5276@1,COG5276@2	NA|NA|NA	S	LVIVD repeat
MAG.T21.18_02759	1189612.A33Q_0007	1.4e-104	386.3	Cytophagia	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	47JX0@768503,4NE8E@976,COG0533@1,COG0533@2	NA|NA|NA	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAG.T21.18_02760	1408473.JHXO01000004_gene166	2.2e-165	590.5	Bacteroidia													Bacteria	2FNBJ@200643,4NF7F@976,COG2911@1,COG2911@2	NA|NA|NA	S	Psort location OuterMembrane, score 9.49
MAG.T21.18_02761	1123276.KB893246_gene561	5.4e-28	132.9	Cytophagia	nosZ		1.7.2.4,3.2.1.22	ko:K00376,ko:K07407	ko00052,ko00561,ko00600,ko00603,ko00910,ko01120,map00052,map00561,map00600,map00603,map00910,map01120	M00529	R01101,R01103,R01104,R01194,R01329,R02804,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451,RC02861	ko00000,ko00001,ko00002,ko01000				Bacteria	47NUN@768503,4NJDV@976,COG2010@1,COG2010@2,COG3345@1,COG3345@2,COG4625@1,COG4625@2	NA|NA|NA	E	PFAM Di-glucose binding within endoplasmic reticulum
MAG.T21.18_02763	1122605.KB893637_gene3389	2.5e-48	198.4	Sphingobacteriia	bepE_4			ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718			ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2			Bacteria	1IP63@117747,4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.18_02764	518766.Rmar_0903	4.4e-58	232.3	Bacteroidetes Order II. Incertae sedis	tolC												Bacteria	1FIV8@1100069,4NEMI@976,COG1538@1,COG1538@2	NA|NA|NA	MU	Outer membrane efflux protein
MAG.T21.18_02765	880073.Calab_2264	7.8e-75	287.7	Bacteria	lpqC		3.2.1.4	ko:K01179,ko:K03932	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		CE1,GH5,GH9		Bacteria	COG2730@1,COG2730@2,COG3509@1,COG3509@2	NA|NA|NA	Q	xylan catabolic process
MAG.T21.18_02766	1434325.AZQN01000003_gene1939	2.1e-20	105.5	Cytophagia				ko:K13993	ko04141,map04141				ko00000,ko00001,ko03110				Bacteria	47R7Q@768503,4NQXY@976,COG0071@1,COG0071@2	NA|NA|NA	O	Belongs to the small heat shock protein (HSP20) family
MAG.T21.18_02767	926562.Oweho_2276	1.2e-42	181.8	Flavobacteriia													Bacteria	1I00F@117743,4NFXV@976,COG4886@1,COG4886@2	NA|NA|NA	O	Tetratricopeptide repeat
MAG.T21.18_02768	216432.CA2559_05580	2.6e-34	154.1	Flavobacteriia													Bacteria	1I00F@117743,4NFXV@976,COG4886@1,COG4886@2	NA|NA|NA	O	Tetratricopeptide repeat
MAG.T21.18_02769	746697.Aeqsu_2200	1.4e-43	184.9	Flavobacteriia													Bacteria	1I00F@117743,4NFXV@976,COG4886@1,COG4886@2	NA|NA|NA	O	Tetratricopeptide repeat
MAG.T21.18_02770	926562.Oweho_2276	5.2e-38	166.4	Flavobacteriia													Bacteria	1I00F@117743,4NFXV@976,COG4886@1,COG4886@2	NA|NA|NA	O	Tetratricopeptide repeat
MAG.T21.18_02774	1392490.JHZX01000001_gene2056	3.2e-66	258.1	Flavobacteriia													Bacteria	1I1AG@117743,4NMJ9@976,COG2318@1,COG2318@2	NA|NA|NA	S	Protein of unknown function (DUF1572)
MAG.T21.18_02775	391587.KAOT1_12877	4.6e-63	248.8	Flavobacteriia	pqiA1			ko:K03808					ko00000				Bacteria	1I22G@117743,4PQ19@976,COG2995@1,COG2995@2	NA|NA|NA	S	Paraquat-inducible protein A
MAG.T21.18_02776	926549.KI421517_gene2007	2e-109	403.3	Cytophagia				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	47JJN@768503,4NDUK@976,COG0577@1,COG0577@2	NA|NA|NA	V	FtsX-like permease family
MAG.T21.18_02777	755732.Fluta_4076	3.7e-114	417.9	Cryomorphaceae	parE		5.99.1.3	ko:K02470,ko:K02622					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1HWNY@117743,2PAF4@246874,4NF18@976,COG0187@1,COG0187@2	NA|NA|NA	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
MAG.T21.18_02780	1453500.AT05_03930	6.8e-295	1020.0	Flavobacteriia	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1HWVT@117743,4NERI@976,COG0188@1,COG0188@2	NA|NA|NA	L	Belongs to the type II topoisomerase GyrA ParC subunit family
MAG.T21.18_02781	765911.Thivi_1503	4.9e-12	77.4	Bacteria				ko:K07171					ko00000,ko01000,ko02048				Bacteria	COG2337@1,COG2337@2	NA|NA|NA	T	Toxic component of a toxin-antitoxin (TA) module
MAG.T21.18_02783	690850.Desaf_2628	1.2e-58	233.4	Desulfovibrionales				ko:K07090					ko00000				Bacteria	1RBHH@1224,2MAXH@213115,2WNRJ@28221,42R9E@68525,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.18_02784	641524.ADICYQ_1379	4.8e-56	224.6	Cytophagia			1.20.4.1	ko:K03741					ko00000,ko01000				Bacteria	47PXK@768503,4NE8C@976,COG0394@1,COG0394@2	NA|NA|NA	T	PFAM Low molecular weight phosphotyrosine protein phosphatase
MAG.T21.18_02786	1121288.AULL01000019_gene1529	3.1e-100	371.7	Flavobacteriia	arsM		2.1.1.137,2.1.1.79	ko:K00574,ko:K07755					ko00000,ko01000				Bacteria	1HYS0@117743,4NEUC@976,COG0500@1,COG2226@2	NA|NA|NA	Q	ubiE/COQ5 methyltransferase family
MAG.T21.18_02787	743722.Sph21_0235	3e-32	144.4	Sphingobacteriia													Bacteria	1IY9H@117747,4NQK3@976,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
MAG.T21.18_02788	700598.Niako_6183	6.6e-12	77.8	Sphingobacteriia	amyB3												Bacteria	1IUCS@117747,4NY26@976,COG4733@1,COG4733@2	NA|NA|NA	S	SPTR Putative
MAG.T21.18_02793	1227266.HMPREF1551_01926	1.6e-64	253.1	Capnocytophaga	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147			iJN746.PP_4715	Bacteria	1EQ1B@1016,1HY7Y@117743,4NE2F@976,COG0149@1,COG0149@2	NA|NA|NA	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAG.T21.18_02794	445961.IW15_08965	4e-60	238.4	Chryseobacterium	prmA			ko:K02687					ko00000,ko01000,ko03009				Bacteria	1HXXE@117743,3ZNXZ@59732,4NFRW@976,COG2264@1,COG2264@2	NA|NA|NA	J	Methylates ribosomal protein L11
MAG.T21.18_02795	926562.Oweho_3351	2e-243	849.7	Cryomorphaceae													Bacteria	1I791@117743,28I1Q@1,2PA5S@246874,2Z869@2,4NH2E@976	NA|NA|NA		
MAG.T21.18_02796	1300143.CCAV010000005_gene3779	3.6e-22	112.5	Chryseobacterium	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005			ic_1306.c0216	Bacteria	1IJH1@117743,3ZSN9@59732,4P1AA@976,COG1044@1,COG1044@2	NA|NA|NA	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAG.T21.18_02797	760192.Halhy_5276	3e-12	81.3	Bacteroidetes			3.2.1.78	ko:K19355	ko00051,map00051		R01332	RC00467	ko00000,ko00001,ko01000				Bacteria	4NJJS@976,COG3934@1,COG3934@2	NA|NA|NA	G	Pkd domain containing protein
MAG.T21.18_02798	1408433.JHXV01000030_gene1416	1.3e-13	84.7	Flavobacteriia													Bacteria	1IJFE@117743,4NEVC@976,COG1520@1,COG1520@2	NA|NA|NA	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAG.T21.18_02799	742725.HMPREF9450_01421	7.1e-49	200.7	Rikenellaceae	plsY		2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	22V7V@171550,2FVDT@200643,4NMU3@976,COG0344@1,COG0344@2	NA|NA|NA	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAG.T21.18_02801	1385935.N836_10990	7.6e-43	179.9	Oscillatoriales			3.4.21.26	ko:K01322	ko04614,map04614				ko00000,ko00001,ko01000,ko01002				Bacteria	1G1B7@1117,1H87F@1150,COG1505@1,COG1505@2	NA|NA|NA	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain
MAG.T21.18_02802	1317122.ATO12_24670	6.9e-88	330.9	Aquimarina				ko:K15977					ko00000				Bacteria	1I0YP@117743,2YJR6@290174,4NK73@976,COG2259@1,COG2259@2	NA|NA|NA	S	Doxx family
MAG.T21.18_02803	1121373.KB903662_gene156	1.5e-37	162.5	Cytophagia	ymaD												Bacteria	47QD5@768503,4NNF7@976,COG1764@1,COG1764@2	NA|NA|NA	O	redox protein regulator of disulfide bond formation
MAG.T21.18_02804	1166018.FAES_1638	6.5e-100	370.5	Cytophagia	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	47KZ9@768503,4NEVE@976,COG0623@1,COG0623@2	NA|NA|NA	I	Enoyl- acyl-carrier-protein reductase NADH
MAG.T21.18_02805	1122176.KB903551_gene4274	1.8e-109	404.4	Bacteria			3.2.1.14	ko:K01183,ko:K20274	ko00520,ko01100,ko02024,map00520,map01100,map02024		R01206,R02334	RC00467	ko00000,ko00001,ko01000,ko01002		GH18		Bacteria	COG3227@1,COG3227@2	NA|NA|NA	E	Zinc metalloprotease (Elastase)
MAG.T21.18_02806	984262.SGRA_2830	6e-118	432.2	Sphingobacteriia			3.4.21.107,3.4.21.50	ko:K01337,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1IW78@117747,4PKT1@976,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like peptidase domain
MAG.T21.18_02807	985255.APHJ01000019_gene559	2e-77	297.4	Gillisia													Bacteria	1HZTV@117743,2P665@244698,4NHWZ@976,COG1572@1,COG1572@2	NA|NA|NA	E	endonuclease I
MAG.T21.18_02808	1211813.CAPH01000003_gene1354	8.2e-102	377.9	Rikenellaceae	recN			ko:K03631					ko00000,ko03400				Bacteria	22U97@171550,2FMIG@200643,4NE3I@976,COG0497@1,COG0497@2	NA|NA|NA	L	May be involved in recombinational repair of damaged DNA
MAG.T21.18_02809	886379.AEWI01000024_gene341	6.3e-64	251.1	Marinilabiliaceae													Bacteria	28HA8@1,2FP92@200643,2Z7MQ@2,3XISK@558415,4NEJD@976	NA|NA|NA	S	Domain of unknown function (DUF4835)
MAG.T21.18_02810	657309.BXY_43330	6.7e-109	401.0	Bacteroidaceae	coaBC		4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000				Bacteria	2FNDG@200643,4AKAP@815,4NE46@976,COG0452@1,COG0452@2	NA|NA|NA	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAG.T21.18_02811	509635.N824_05600	3.6e-28	131.0	Sphingobacteriia	rpoZ												Bacteria	1IY6M@117747,2CT4B@1,32SSJ@2,4NQ76@976	NA|NA|NA	S	RNA polymerase Rpb6
MAG.T21.18_02812	1453500.AT05_04920	3e-47	195.7	Flavobacteriia	yfiO			ko:K05807,ko:K08309					ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23		Bacteria	1HYEQ@117743,4NJ5A@976,COG4105@1,COG4105@2	NA|NA|NA	S	Outer membrane assembly lipoprotein YfiO
MAG.T21.18_02813	755732.Fluta_2289	9.1e-75	287.0	Cryomorphaceae	gldL												Bacteria	1HYV7@117743,28IG3@1,2PAW7@246874,2Z8HM@2,4NFJR@976	NA|NA|NA	S	Gliding motility protein GldL
MAG.T21.18_02814	755732.Fluta_2288	3.9e-158	564.7	Cryomorphaceae	gldK												Bacteria	1HXXN@117743,2PAKH@246874,4NGY2@976,COG1262@1,COG1262@2	NA|NA|NA	S	Sulfatase-modifying factor enzyme 1
MAG.T21.18_02815	926562.Oweho_2802	2.7e-49	202.6	Bacteroidetes													Bacteria	4PKGM@976,COG0226@1,COG0226@2	NA|NA|NA	P	Type IX secretion system membrane protein PorP/SprF
MAG.T21.18_02816	929556.Solca_4041	6.7e-106	391.0	Sphingobacteriia			3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQD9@117747,4NE5W@976,COG0010@1,COG0010@2	NA|NA|NA	E	Belongs to the arginase family
MAG.T21.18_02817	1166018.FAES_4496	1e-263	916.4	Cytophagia	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168					ko00000,ko01000,ko03032,ko03400				Bacteria	47K7C@768503,4NF9S@976,COG0550@1,COG0550@2,COG1754@1,COG1754@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAG.T21.18_02818	760192.Halhy_1443	6.9e-53	213.8	Sphingobacteriia	msrB		1.8.4.12	ko:K07305					ko00000,ko01000				Bacteria	1J0CH@117747,4NP9M@976,COG0229@1,COG0229@2	NA|NA|NA	O	SelR domain
MAG.T21.18_02820	484018.BACPLE_00813	1.9e-11	75.9	Bacteroidaceae													Bacteria	295Z7@1,2FPCX@200643,2ZTA0@2,4AK6F@815,4NP7A@976	NA|NA|NA	S	COG NOG14441 non supervised orthologous group
MAG.T21.18_02823	755732.Fluta_2284	1.1e-160	573.2	Cryomorphaceae	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168			R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016				Bacteria	1HX6T@117743,2PAFK@246874,4NDU6@976,COG0621@1,COG0621@2	NA|NA|NA	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MAG.T21.18_02824	926549.KI421517_gene3104	5.1e-125	454.5	Cytophagia	nifA			ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512			ko00000,ko00001,ko00002,ko02022,ko02035				Bacteria	47JXW@768503,4NDWI@976,COG2204@1,COG2204@2	NA|NA|NA	K	sigma54 specific, transcriptional regulator, Fis family
MAG.T21.18_02825	926562.Oweho_2808	6.5e-32	144.1	Cryomorphaceae													Bacteria	1IGJ9@117743,2CADI@1,2PB9D@246874,315ID@2,4PJQG@976	NA|NA|NA	S	Lipopolysaccharide-assembly
MAG.T21.18_02826	1408813.AYMG01000001_gene3687	8.6e-13	81.6	Sphingobacteriia													Bacteria	1ISZD@117747,28HHN@1,2Z7TA@2,4NEXR@976	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.18_02827	1453498.LG45_06530	1.6e-14	85.5	Flavobacterium	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1I418@117743,2NX2F@237,4NUYQ@976,COG1314@1,COG1314@2	NA|NA|NA	U	Preprotein translocase subunit SecG
MAG.T21.18_02828	1356852.N008_16760	2.5e-30	137.9	Cytophagia	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220		ko:K04078					ko00000,ko03029,ko03110				Bacteria	47QCW@768503,4NS7D@976,COG0234@1,COG0234@2	NA|NA|NA	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAG.T21.18_02830	1392490.JHZX01000001_gene869	1.3e-134	488.0	Flavobacteriia			3.4.21.72	ko:K01347					ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1HXFW@117743,4NG93@976,COG1361@1,COG1361@2,COG4886@1,COG4886@2,COG4932@1,COG4932@2	NA|NA|NA	M	regulator of chromosome condensation, RCC1
MAG.T21.18_02831	1239962.C943_04524	3.1e-104	385.2	Cytophagia	pfkA		2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019				Bacteria	47JHZ@768503,4NF8F@976,COG0205@1,COG0205@2	NA|NA|NA	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MAG.T21.18_02834	1121904.ARBP01000002_gene6983	7.9e-154	551.2	Cytophagia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	47JDS@768503,4PKF2@976,COG4206@1,COG4206@2	NA|NA|NA	H	TonB-dependent Receptor Plug
MAG.T21.18_02835	1122176.KB903535_gene2036	9.8e-34	150.2	Sphingobacteriia													Bacteria	1IZHS@117747,29TMV@1,30EVG@2,4NNPM@976	NA|NA|NA		
MAG.T21.18_02836	391587.KAOT1_10501	5.1e-41	174.5	Bacteria													Bacteria	COG1376@1,COG1376@2	NA|NA|NA	D	ErfK ybiS ycfS ynhG family protein
MAG.T21.18_02837	118166.JH976537_gene1161	8.2e-30	136.7	Oscillatoriales				ko:K06934					ko00000				Bacteria	1G86Y@1117,1HBMJ@1150,COG1661@1,COG1661@2	NA|NA|NA	S	DNA-binding protein with PD1-like DNA-binding motif
MAG.T21.18_02838	485917.Phep_1897	3.2e-54	218.0	Sphingobacteriia	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000			iJN678.purE,iNJ661.Rv3275c	Bacteria	1IRVT@117747,4NME9@976,COG0041@1,COG0041@2	NA|NA|NA	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAG.T21.18_02839	246195.DNO_0078	2e-94	352.8	Gammaproteobacteria	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000			iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	Bacteria	1MU70@1224,1RQEI@1236,COG0026@1,COG0026@2	NA|NA|NA	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MAG.T21.18_02840	1202532.FF52_09007	5.8e-17	94.7	Flavobacterium													Bacteria	1I34P@117743,2NWCZ@237,4NR9K@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.18_02841	938709.AUSH02000045_gene473	7e-73	280.4	Bacteroidetes	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1718	Bacteria	4NDXB@976,COG0036@1,COG0036@2	NA|NA|NA	G	Belongs to the ribulose-phosphate 3-epimerase family
MAG.T21.18_02842	1453500.AT05_04545	2.6e-113	415.2	Flavobacteriia	rpoD			ko:K03086					ko00000,ko03021				Bacteria	1HWSN@117743,4NEBF@976,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MAG.T21.18_02843	886379.AEWI01000122_gene1860	6e-74	284.3	Marinilabiliaceae	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	2FN5H@200643,3XJ8Y@558415,4NE4Q@976,COG1185@1,COG1185@2	NA|NA|NA	J	Polyribonucleotide nucleotidyltransferase, RNA binding domain
MAG.T21.18_02844	1408433.JHXV01000017_gene1592	6.2e-43	179.9	Cryomorphaceae	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0661	Bacteria	1HWPA@117743,2PAI4@246874,4NEQ0@976,COG0458@1,COG0458@2	NA|NA|NA	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain
MAG.T21.18_02845	866536.Belba_2754	4.9e-21	107.5	Cytophagia													Bacteria	2CRSQ@1,32SPK@2,47RXT@768503,4NR94@976	NA|NA|NA	S	DoxX-like family
MAG.T21.18_02846	1122605.KB893646_gene209	1.4e-57	229.2	Sphingobacteriia													Bacteria	1IXSB@117747,29XQK@1,30JGA@2,4NNS6@976	NA|NA|NA		
MAG.T21.18_02847	762903.Pedsa_1654	8.5e-41	173.3	Sphingobacteriia	emrR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141											Bacteria	1IT2W@117747,4NNK0@976,COG1846@1,COG1846@2	NA|NA|NA	K	Regulatory protein MarR
MAG.T21.18_02848	592029.DDD_3272	1.7e-23	115.2	Nonlabens	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0661	Bacteria	1HWPA@117743,3HKYT@363408,4NEQ0@976,COG0458@1,COG0458@2	NA|NA|NA	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MAG.T21.18_02852	671143.DAMO_0449	3.8e-45	189.5	Bacteria													Bacteria	COG1572@1,COG1572@2	NA|NA|NA	NU	bacterial-type flagellum-dependent cell motility
MAG.T21.18_02853	1463900.JOIX01000002_gene5244	4e-46	191.0	Actinobacteria			3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100		R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000				Bacteria	2IFKS@201174,COG0346@1,COG0346@2	NA|NA|NA	E	glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.18_02856	926562.Oweho_0665	2.3e-15	88.6	Bacteria			1.1.9.1	ko:K17760					ko00000,ko01000				Bacteria	COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.18_02858	1121931.AUHG01000010_gene525	3e-65	255.0	Flavobacteriia													Bacteria	1I5UF@117743,28PQP@1,2ZCCM@2,4NSQ2@976	NA|NA|NA	S	Domain of unknown function (DUF4386)
MAG.T21.18_02859	329726.AM1_3891	1.8e-10	72.4	Cyanobacteria	atmc2												Bacteria	1GHQ3@1117,COG4249@1,COG4249@2	NA|NA|NA	S	Agenet domain
MAG.T21.18_02863	1379270.AUXF01000007_gene966	4.6e-65	254.6	Gemmatimonadetes			1.1.1.219	ko:K00091					ko00000,ko01000				Bacteria	1ZUPC@142182,COG0702@1,COG0702@2	NA|NA|NA	GM	epimerase
MAG.T21.18_02864	385682.AFSL01000040_gene257	2.8e-67	262.3	Marinilabiliaceae	oxyR	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141		ko:K04761	ko02026,map02026				ko00000,ko00001,ko03000				Bacteria	2FNH6@200643,3XJM8@558415,4NGZ5@976,COG0583@1,COG0583@2	NA|NA|NA	K	Bacterial regulatory helix-turn-helix protein, lysR family
MAG.T21.18_02865	1506583.JQJY01000004_gene2921	1.7e-223	782.3	Flavobacterium	ptpA												Bacteria	1HY8A@117743,2NTHN@237,4NFBK@976,COG1506@1,COG1506@2	NA|NA|NA	E	Peptidase S9
MAG.T21.18_02866	1343740.M271_36280	7.8e-21	108.6	Actinobacteria				ko:K14340					ko00000,ko01000,ko01003				Bacteria	2GN7C@201174,COG5305@1,COG5305@2	NA|NA|NA	S	Dolichyl-phosphate-mannose-protein mannosyltransferase
MAG.T21.18_02867	1385511.N783_15690	5.6e-26	124.0	Bacilli	yitI												Bacteria	1V7CI@1239,4HJ4S@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
MAG.T21.18_02869	525373.HMPREF0766_12073	8.1e-155	553.5	Sphingobacteriia	frvX		3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	1INSP@117747,4NG97@976,COG1363@1,COG1363@2	NA|NA|NA	G	peptidase M42
MAG.T21.18_02870	1356852.N008_12215	2.1e-125	456.4	Cytophagia													Bacteria	47NZ4@768503,4NHCE@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	MU	OmpA family
MAG.T21.18_02871	755732.Fluta_2592	6.6e-189	667.2	Cryomorphaceae	porX			ko:K03413	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko02022,ko02035				Bacteria	1HY11@117743,2PAEX@246874,4NE72@976,COG2204@1,COG2204@2	NA|NA|NA	T	CheY-like receiver AAA-type ATPase and DNA-binding domains
MAG.T21.18_02873	1550091.JROE01000004_gene1413	1.7e-28	132.5	Sphingobacteriia	yjeE		2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100		R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016				Bacteria	1ISTA@117747,4NS89@976,COG0802@1,COG0802@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0079, ATPase
MAG.T21.18_02874	755732.Fluta_2594	1.8e-141	509.2	Cryomorphaceae	ald		1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000				Bacteria	1HWYE@117743,2PAIE@246874,4NE8F@976,COG0686@1,COG0686@2	NA|NA|NA	C	PFAM Alanine dehydrogenase PNT, C-terminal domain
MAG.T21.18_02876	1173264.KI913949_gene167	4.5e-11	74.3	Oscillatoriales													Bacteria	1GAUQ@1117,1HFHI@1150,2EHW5@1,33BMQ@2	NA|NA|NA		
MAG.T21.18_02877	509635.N824_03480	1.8e-114	419.5	Sphingobacteriia	putA			ko:K00318,ko:K18318	ko00330,ko00332,ko01100,ko01110,ko01130,ko02024,map00330,map00332,map01100,map01110,map01130,map02024		R10507	RC00083	ko00000,ko00001,ko01000				Bacteria	1IQ4H@117747,4NEH5@976,COG0506@1,COG0506@2	NA|NA|NA	E	Proline dehydrogenase
MAG.T21.18_02878	1392490.JHZX01000001_gene869	4.5e-81	309.3	Flavobacteriia			3.4.21.72	ko:K01347					ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3			Bacteria	1HXFW@117743,4NG93@976,COG1361@1,COG1361@2,COG4886@1,COG4886@2,COG4932@1,COG4932@2	NA|NA|NA	M	regulator of chromosome condensation, RCC1
MAG.T21.18_02879	997829.HMPREF1121_00317	9.8e-84	316.6	Porphyromonadaceae	ppm1		2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100		R01009	RC00005	ko00000,ko00001,ko01000,ko01003		GT2		Bacteria	22WKN@171551,2FM3A@200643,4NEHI@976,COG1216@1,COG1216@2	NA|NA|NA	S	Dolichyl-phosphate beta-D-mannosyltransferase
MAG.T21.18_02880	762903.Pedsa_1710	1.8e-147	529.3	Sphingobacteriia	pyrC		3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQSD@117747,4NE3T@976,COG0044@1,COG0044@2	NA|NA|NA	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
MAG.T21.18_02882	926562.Oweho_1972	6e-66	258.1	Cryomorphaceae			1.1.1.219	ko:K00091					ko00000,ko01000				Bacteria	1HX0P@117743,2PAN2@246874,4NFZH@976,COG0451@1,COG0451@2	NA|NA|NA	M	NAD(P)H-binding
MAG.T21.18_02883	1122176.KB903576_gene5010	8.6e-64	251.5	Sphingobacteriia													Bacteria	1IVY8@117747,4NF0B@976,COG2133@1,COG2133@2,COG4886@1,COG4886@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.18_02886	1122176.KB903543_gene584	8.8e-32	144.1	Sphingobacteriia													Bacteria	1J0YX@117747,2CG1Y@1,31EK1@2,4NUTU@976	NA|NA|NA	S	Protein of unknown function (DUF1573)
MAG.T21.18_02887	743722.Sph21_1401	1e-33	149.4	Sphingobacteriia													Bacteria	1IT90@117747,4NNVM@976,COG3682@1,COG3682@2	NA|NA|NA	K	Penicillinase repressor
MAG.T21.18_02888	1185876.BN8_00370	1.5e-46	193.7	Cytophagia													Bacteria	47YB7@768503,4NW2E@976,COG0810@1,COG0810@2	NA|NA|NA	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.18_02889	1237149.C900_01299	7.8e-22	109.8	Cytophagia				ko:K07461					ko00000				Bacteria	47RSS@768503,4NUYX@976,COG2827@1,COG2827@2	NA|NA|NA	L	GIY-YIG catalytic domain
MAG.T21.18_02890	412597.AEPN01000025_gene338	3e-30	137.9	Paracoccus				ko:K07483					ko00000				Bacteria	1NH66@1224,2PXKS@265,2UD9V@28211,COG2963@1,COG2963@2	NA|NA|NA	L	Associated with IS66-like transposable element, conserved
MAG.T21.18_02891	1410620.SHLA_14c000720	1.4e-178	632.5	Rhizobiaceae	fabF	GO:0006996,GO:0008150,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0016043,GO:0061024,GO:0071840	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1MU1X@1224,2TSNN@28211,4BASW@82115,COG0304@1,COG0304@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MAG.T21.18_02892	311403.Arad_2402	8.5e-58	229.9	Rhizobiaceae													Bacteria	1RHQK@1224,2UAWX@28211,4BAMB@82115,COG1733@1,COG1733@2	NA|NA|NA	K	HxlR-like helix-turn-helix
MAG.T21.18_02893	1116369.KB890024_gene706	4.5e-180	637.1	Phyllobacteriaceae													Bacteria	1PM16@1224,2U1M0@28211,43GTS@69277,COG0583@1,COG0583@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.18_02894	1122605.KB893628_gene4483	3.5e-112	411.8	Sphingobacteriia	pit			ko:K03306					ko00000	2.A.20			Bacteria	1IPR3@117747,4NE7J@976,COG0306@1,COG0306@2	NA|NA|NA	P	phosphate transporter
MAG.T21.18_02895	1122605.KB893628_gene4482	3e-47	195.3	Sphingobacteriia				ko:K07220					ko00000				Bacteria	1INNB@117747,4NI25@976,COG1392@1,COG1392@2	NA|NA|NA	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)
MAG.T21.18_02896	1120965.AUBV01000001_gene3273	8.9e-119	433.7	Cytophagia													Bacteria	47K0B@768503,4NH24@976,COG3746@1,COG3746@2	NA|NA|NA	P	Phosphate-selective porin O and P
MAG.T21.18_02897	1121930.AQXG01000008_gene197	2.1e-79	302.0	Bacteroidetes	paaY	GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009437,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0044237,GO:0071704,GO:0097164,GO:1901564		ko:K02617,ko:K08279					ko00000				Bacteria	4NG5P@976,COG0663@1,COG0663@2	NA|NA|NA	S	Bacterial transferase hexapeptide repeat
MAG.T21.18_02898	1121373.KB903643_gene3662	1.1e-21	109.4	Cytophagia													Bacteria	2E3V1@1,32YSA@2,47S3J@768503,4NV88@976	NA|NA|NA		
MAG.T21.18_02899	471854.Dfer_2981	2.4e-38	164.9	Cytophagia				ko:K09922					ko00000				Bacteria	47QJ9@768503,4NQH4@976,COG3169@1,COG3169@2	NA|NA|NA	S	Putative member of DMT superfamily (DUF486)
MAG.T21.18_02900	1279009.ADICEAN_00402	1.1e-161	577.0	Cytophagia	kefC			ko:K03455					ko00000	2.A.37			Bacteria	47NEG@768503,4NGF6@976,COG0475@1,COG0475@2,COG1226@1,COG1226@2	NA|NA|NA	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MAG.T21.18_02901	643473.KB235930_gene1520	8.1e-114	417.5	Nostocales													Bacteria	1G1RZ@1117,1HMJF@1161,COG4402@1,COG4402@2	NA|NA|NA	S	protein conserved in bacteria (DUF2330)
MAG.T21.18_02902	118173.KB235914_gene1431	1.6e-56	226.5	Oscillatoriales	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347,ko:K21163	ko01059,ko01130,map01059,map01130	M00824			ko00000,ko00001,ko00002,ko01000				Bacteria	1G382@1117,1H8UQ@1150,COG1805@1,COG1805@2	NA|NA|NA	U	Belongs to the NqrB RnfD family
MAG.T21.18_02903	983917.RGE_36740	3.9e-15	87.8	unclassified Burkholderiales													Bacteria	1KNT2@119065,1N8Z8@1224,2VW99@28216,COG0745@1,COG0745@2	NA|NA|NA	KT	cheY-homologous receiver domain
MAG.T21.18_02904	700598.Niako_1503	1.2e-16	92.8	Sphingobacteriia				ko:K07705	ko02020,map02020	M00492			ko00000,ko00001,ko00002,ko02022				Bacteria	1J0BD@117747,4NF8A@976,COG3279@1,COG3279@2	NA|NA|NA	T	SMART Signal transduction response regulator, receiver
MAG.T21.18_02905	1035191.HMPREF0185_02413	1.8e-21	109.8	Caulobacterales			2.7.13.3	ko:K11527					ko00000,ko01000,ko01001,ko02022				Bacteria	1R5EN@1224,2KJWT@204458,2TW7J@28211,COG3437@1,COG3437@2,COG5002@1,COG5002@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
MAG.T21.18_02906	1122176.KB903535_gene1979	6.5e-77	294.3	Bacteroidetes													Bacteria	4NHGS@976,COG1278@1,COG1278@2,COG1432@1,COG1432@2	NA|NA|NA	K	Cold-shock DNA-binding domain protein
MAG.T21.18_02908	1220534.B655_0979	1.3e-36	161.0	Archaea													Archaea	COG2203@1,arCOG02361@2157	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.18_02909	926562.Oweho_2853	2.1e-08	64.3	Cryomorphaceae	pcrB	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576		ko:K07094					ko00000,ko01000				Bacteria	1HYFZ@117743,2PASJ@246874,4NER8@976,COG1646@1,COG1646@2	NA|NA|NA	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)
MAG.T21.18_02910	1453505.JASY01000001_gene3542	5.9e-83	315.5	Flavobacterium			4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYQY@117743,2NUIW@237,4NEVN@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2	NA|NA|NA	T	Adenylyl- / guanylyl cyclase, catalytic domain
MAG.T21.18_02911	1313421.JHBV01000022_gene4763	1.6e-09	71.6	Sphingobacteriia			3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100		R01206,R02334	RC00467	ko00000,ko00001,ko01000		GH18		Bacteria	1IW8E@117747,4PI1D@976,COG3227@1,COG3227@2,COG3291@1,COG3291@2	NA|NA|NA	E	Pregnancy-associated plasma protein-A
MAG.T21.18_02912	1122176.KB903536_gene1806	1.2e-194	686.8	Sphingobacteriia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1IPNU@117747,4PKTE@976,COG4772@1,COG4772@2	NA|NA|NA	P	PFAM TonB-dependent Receptor
MAG.T21.18_02913	1279009.ADICEAN_02215	1.6e-28	132.9	Cytophagia	nadR												Bacteria	47QMU@768503,4NFNZ@976,COG3172@1,COG3172@2	NA|NA|NA	H	ATPase kinase involved in NAD metabolism
MAG.T21.18_02914	926562.Oweho_2152	2.9e-39	170.2	Cryomorphaceae	CP_1076			ko:K07126,ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	1IKH9@117743,2PC6A@246874,4PPAG@976,COG0666@1,COG0666@2,COG5563@1,COG5563@2	NA|NA|NA	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MAG.T21.18_02915	1120968.AUBX01000015_gene3728	3.1e-55	221.9	Cytophagia													Bacteria	2ZZTD@2,47Q57@768503,4NNMY@976,arCOG05416@1	NA|NA|NA	S	lycopene cyclase
MAG.T21.18_02916	929556.Solca_3514	4.4e-23	114.8	Sphingobacteriia	pnuC			ko:K03811					ko00000,ko02000	4.B.1.1			Bacteria	1IYHJ@117747,4NFJI@976,COG3201@1,COG3201@2	NA|NA|NA	H	Nicotinamide mononucleotide transporter
MAG.T21.18_02918	929556.Solca_2956	8.6e-89	334.0	Sphingobacteriia	ribF		2.7.1.26,2.7.7.2	ko:K07011,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQGU@117747,4NEI9@976,COG0196@1,COG0196@2	NA|NA|NA	H	Belongs to the ribF family
MAG.T21.18_02919	1286632.P278_10940	1.4e-129	469.5	Flavobacteriia	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02836					ko00000,ko03012				Bacteria	1HXZY@117743,4NEN1@976,COG1186@1,COG1186@2	NA|NA|NA	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAG.T21.18_02921	1121373.KB903665_gene3061	3.7e-79	302.0	Cytophagia	nosF			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	47TVR@768503,4NFJD@976,COG1131@1,COG1131@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
MAG.T21.18_02923	1408433.JHXV01000034_gene18	3e-249	868.2	Cryomorphaceae	pcrA		3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1HWYD@117743,2PAG3@246874,4NDWN@976,COG0210@1,COG0210@2	NA|NA|NA	L	UvrD-like helicase C-terminal domain
MAG.T21.18_02924	1408433.JHXV01000002_gene418	8.8e-11	73.9	Cryomorphaceae													Bacteria	1ICT4@117743,2A9C2@1,2PC2E@246874,30YH0@2,4PCAK@976	NA|NA|NA		
MAG.T21.18_02925	1453500.AT05_07775	1.5e-44	186.4	Flavobacteriia													Bacteria	1HXIU@117743,28H5J@1,2Z7I5@2,4NHK6@976	NA|NA|NA	S	Domain of unknown function (DUF4290)
MAG.T21.18_02926	388413.ALPR1_19828	2.3e-179	635.2	Cytophagia	murA		2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011				Bacteria	47JQ7@768503,4NDV8@976,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAG.T21.18_02927	926562.Oweho_3049	1.8e-48	199.1	Cryomorphaceae													Bacteria	1HY1W@117743,2PBV2@246874,4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	CO	PFAM AhpC TSA family
MAG.T21.18_02928	761193.Runsl_3072	5e-39	167.9	Cytophagia	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363		ko:K02652,ko:K03687					ko00000,ko02035,ko02044,ko03029,ko03110	3.A.15.2			Bacteria	47QCT@768503,4NQ6M@976,COG0576@1,COG0576@2	NA|NA|NA	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAG.T21.18_02929	755732.Fluta_0235	8.1e-117	427.2	Cryomorphaceae	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141		ko:K03686					ko00000,ko03029,ko03110				Bacteria	1HXKY@117743,2PAIS@246874,4NF41@976,COG0484@1,COG0484@2	NA|NA|NA	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAG.T21.18_02930	886377.Murru_2406	1.8e-143	515.8	Flavobacteriia	lon		3.4.21.53	ko:K01338	ko04112,map04112				ko00000,ko00001,ko01000,ko01002				Bacteria	1HX2R@117743,4NE1G@976,COG0466@1,COG0466@2	NA|NA|NA	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MAG.T21.18_02932	886377.Murru_1766	1e-36	159.8	Flavobacteriia													Bacteria	1I26C@117743,4NPKP@976,COG4914@1,COG4914@2	NA|NA|NA		
MAG.T21.18_02933	1408433.JHXV01000001_gene768	3.1e-173	615.5	Bacteroidetes													Bacteria	4NTWX@976,COG1404@1,COG1404@2	NA|NA|NA	O	Peptidase, S8 S53 family
MAG.T21.18_02934	1356852.N008_13335	3.2e-111	408.7	Cytophagia	queA		2.4.99.17	ko:K07568					ko00000,ko01000,ko03016				Bacteria	47KMT@768503,4NDZ5@976,COG0809@1,COG0809@2	NA|NA|NA	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MAG.T21.18_02935	926562.Oweho_1573	2.7e-66	259.2	Flavobacteriia	porQ												Bacteria	1HZFD@117743,4NHNC@976,COG2067@1,COG2067@2	NA|NA|NA	I	penicillin-binding protein
MAG.T21.18_02936	1121897.AUGO01000006_gene845	2.9e-64	251.9	Flavobacterium	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.19,2.7.4.25,6.3.2.1	ko:K00800,ko:K00945,ko:K03977,ko:K13799	ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230	M00022,M00052,M00119	R00158,R00512,R01665,R02473,R03460	RC00002,RC00096,RC00141,RC00350	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	1HXBA@117743,2NS6J@237,4NEMB@976,COG0283@1,COG0283@2	NA|NA|NA	F	Belongs to the cytidylate kinase family. Type 1 subfamily
MAG.T21.18_02937	1157634.KB912966_gene2047	9.4e-07	61.2	Actinobacteria													Bacteria	2IB4N@201174,COG4403@1,COG4403@2	NA|NA|NA	V	Lanthionine synthetase C family protein
MAG.T21.18_02938	1237149.C900_00764	2.5e-140	505.4	Cytophagia	ispH		1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011			iIT341.HP0400,iLJ478.TM1444	Bacteria	47M0Y@768503,4NDUX@976,COG0761@1,COG0761@2	NA|NA|NA	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MAG.T21.18_02939	314264.ROS217_04804	4.2e-94	351.3	Alphaproteobacteria				ko:K07480					ko00000				Bacteria	1MV8R@1224,2TURN@28211,COG1662@1,COG1662@2	NA|NA|NA	L	PFAM IS1 transposase
MAG.T21.18_02940	575540.Isop_1349	4.1e-12	79.0	Planctomycetes													Bacteria	2A7FI@1,2J21R@203682,30WD3@2	NA|NA|NA		
MAG.T21.18_02942	391587.KAOT1_19597	5.4e-115	421.0	Flavobacteriia	cphA		6.3.2.13,6.3.2.29,6.3.2.30	ko:K01928,ko:K03802	ko00300,ko00550,map00300,map00550		R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011				Bacteria	1HXFG@117743,4NEDY@976,COG0189@1,COG0189@2,COG0769@1,COG0769@2	NA|NA|NA	HJM	cyanophycin synthetase
MAG.T21.18_02943	313624.NSP_41030	2.8e-123	448.7	Nostocales			2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	1GJPA@1117,1HSWM@1161,COG0270@1,COG0270@2	NA|NA|NA	L	C-5 cytosine-specific DNA methylase
MAG.T21.18_02944	313624.NSP_41020	6e-83	314.7	Nostocales				ko:K07451,ko:K07452					ko00000,ko01000,ko02048				Bacteria	1GKB4@1117,1HTM0@1161,COG3183@1,COG3183@2	NA|NA|NA	L	HNH nucleases
MAG.T21.18_02946	153721.MYP_3250	2.4e-17	95.9	Bacteroidetes	amyB3												Bacteria	4NY26@976,COG4733@1,COG4733@2	NA|NA|NA	S	SPTR Putative
MAG.T21.18_02948	1111069.TCCBUS3UF1_17270	1.9e-47	197.2	Deinococcus-Thermus													Bacteria	1WM7M@1297,COG1572@1,COG1572@2	NA|NA|NA	S	Domain of unknown function (DUF5122) beta-propeller
MAG.T21.18_02949	762903.Pedsa_1149	2e-79	302.4	Sphingobacteriia			3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130		R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000				Bacteria	1IQ0X@117747,4NKMA@976,COG0412@1,COG0412@2	NA|NA|NA	Q	dienelactone hydrolase
MAG.T21.18_02953	1434325.AZQN01000001_gene58	1.3e-21	109.0	Cytophagia	hrpX	GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0030260,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044403,GO:0044409,GO:0044419,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141											Bacteria	47RUM@768503,4NVDF@976,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.18_02954	926551.KB900715_gene2155	3.2e-71	275.0	Capnocytophaga	fhs	GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1EREB@1016,1HXR5@117743,4NG3E@976,COG2759@1,COG2759@2	NA|NA|NA	H	Formyltetrahydrofolate synthetase
MAG.T21.18_02957	1280380.KR100_02380	3.6e-28	133.3	Synechococcus			3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503		R06200,R11307,R11308		ko00000,ko00001,ko01000,ko01002		GH5,GH9		Bacteria	1G1I0@1117,1GZV9@1129,COG2931@1,COG2931@2,COG3420@1,COG3420@2	NA|NA|NA	Q	Hemolysin-type calcium-binding repeat (2 copies)
MAG.T21.18_02958	867900.Celly_2033	1.6e-17	95.1	Flavobacteriia	cspB			ko:K03704					ko00000,ko03000				Bacteria	1I50Z@117743,4NURE@976,COG1278@1,COG1278@2	NA|NA|NA	K	cold-shock protein
MAG.T21.18_02959	471854.Dfer_5355	3.3e-111	408.7	Cytophagia													Bacteria	47M87@768503,4NIE2@976,COG2982@1,COG2982@2	NA|NA|NA	M	Domain of Unknown Function (DUF748)
MAG.T21.18_02960	153721.MYP_4438	5.6e-16	90.9	Cytophagia	hosA			ko:K03575,ko:K06075,ko:K22296,ko:K22489	ko03410,map03410				ko00000,ko00001,ko01000,ko03000,ko03400				Bacteria	47WKE@768503,4NWHB@976,COG1846@1,COG1846@2	NA|NA|NA	K	helix_turn_helix multiple antibiotic resistance protein
MAG.T21.18_02961	1121930.AQXG01000001_gene1272	3.9e-76	292.0	Sphingobacteriia				ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718			ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6			Bacteria	1IQN0@117747,4NERP@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.18_02964	984262.SGRA_2830	9.1e-128	464.5	Sphingobacteriia			3.4.21.107,3.4.21.50	ko:K01337,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1IW78@117747,4PKT1@976,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like peptidase domain
MAG.T21.18_02965	1396418.BATQ01000166_gene1914	7e-17	94.4	Bacteria													Bacteria	COG1434@1,COG1434@2	NA|NA|NA	S	Gram-negative-bacterium-type cell wall biogenesis
MAG.T21.18_02966	929556.Solca_0293	4.5e-121	442.2	Sphingobacteriia	xynX5												Bacteria	1IRAV@117747,4NER3@976,COG2304@1,COG2304@2	NA|NA|NA	S	oxidoreductase activity
MAG.T21.18_02967	929556.Solca_0931	2.1e-102	380.2	Sphingobacteriia													Bacteria	1J0JA@117747,4PM6M@976,COG1572@1,COG1572@2	NA|NA|NA	S	Aerotolerance regulator N-terminal
MAG.T21.18_02968	761193.Runsl_1787	6.5e-94	351.3	Cytophagia	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	47KKP@768503,4NDUZ@976,COG0044@1,COG0044@2	NA|NA|NA	F	TIGRFAM dihydroorotase, multifunctional complex type
MAG.T21.18_02969	1408433.JHXV01000001_gene927	3.2e-13	82.0	Cryomorphaceae				ko:K05807					ko00000,ko02000	1.B.33.1			Bacteria	1IBBB@117743,2PC55@246874,4P7J6@976,COG1729@1,COG1729@2	NA|NA|NA	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MAG.T21.18_02970	313590.MED134_02985	1e-62	246.5	Dokdonia	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462					ko00000,ko01000				Bacteria	1HX7M@117743,37DXU@326319,4NFB4@976,COG0242@1,COG0242@2	NA|NA|NA	J	Polypeptide deformylase
MAG.T21.18_02971	313595.P700755_002644	1e-27	131.0	Psychroflexus				ko:K08642	ko02024,map02024				ko00000,ko00001,ko01000,ko01002				Bacteria	1IDCY@117743,4C4FG@83612,4PCUY@976,COG0739@1,COG0739@2	NA|NA|NA	M	heme binding
MAG.T21.18_02972	1189612.A33Q_2508	2.3e-281	974.5	Cytophagia	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000			iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	Bacteria	47JUB@768503,4NDY5@976,COG1154@1,COG1154@2	NA|NA|NA	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAG.T21.18_02974	1239962.C943_01555	3.1e-10	72.0	Bacteroidetes													Bacteria	2DD3M@1,2ZGBQ@2,4P80Y@976	NA|NA|NA		
MAG.T21.18_02975	459495.SPLC1_S081700	3.4e-16	93.2	Oscillatoriales													Bacteria	1GR6P@1117,1HAH3@1150,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAG.T21.18_02977	760192.Halhy_5351	2.4e-75	290.0	Bacteroidetes													Bacteria	4NPS7@976,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAG.T21.18_02978	925409.KI911562_gene1538	2.3e-19	100.9	Sphingobacteriia	accC		6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000				Bacteria	1INM0@117747,4NFEQ@976,COG0439@1,COG0439@2	NA|NA|NA	I	acetyl-CoA carboxylase, biotin carboxylase
MAG.T21.18_02980	509635.N824_17220	6.8e-38	163.3	Bacteroidetes													Bacteria	4NNNG@976,COG0346@1,COG0346@2	NA|NA|NA	E	glyoxalase
MAG.T21.18_02982	385682.AFSL01000110_gene2854	2.5e-39	168.7	Marinilabiliaceae													Bacteria	2FQUU@200643,3XJYR@558415,4NGFR@976,COG1230@1,COG1230@2	NA|NA|NA	P	Cation efflux family
MAG.T21.18_02983	1550091.JROE01000002_gene1118	4.2e-43	180.6	Sphingobacteriia													Bacteria	1ISFJ@117747,4NQ4W@976,COG4898@1,COG4898@2	NA|NA|NA	S	Uncharacterized protein conserved in bacteria (DUF2200)
MAG.T21.18_02984	1123008.KB905704_gene478	5.6e-152	544.7	Bacteroidetes													Bacteria	4NH87@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_02986	1245469.S58_44520	1.2e-48	199.9	Bradyrhizobiaceae													Bacteria	1N8RQ@1224,2CUGC@1,2UIPV@28211,32SV9@2,3K5EP@41294	NA|NA|NA		
MAG.T21.18_02987	388399.SSE37_10038	2.1e-101	375.9	Alphaproteobacteria													Bacteria	1R63V@1224,2U1N6@28211,COG1479@1,COG1479@2	NA|NA|NA	S	Protein of unknown function DUF262
MAG.T21.18_02988	755732.Fluta_1926	4.3e-82	310.8	Cryomorphaceae	aldA		1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWQG@117743,2PBC6@246874,4NEB7@976,COG1012@1,COG1012@2	NA|NA|NA	C	Aldehyde dehydrogenase family
MAG.T21.18_02992	760192.Halhy_5161	9.5e-198	697.2	Sphingobacteriia	tbpA			ko:K02014,ko:K16087					ko00000,ko02000	1.B.14,1.B.14.2			Bacteria	1IQ77@117747,4NFW1@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.18_02993	760192.Halhy_5160	1.3e-43	184.1	Sphingobacteriia													Bacteria	1ITET@117747,4NIB0@976,COG4085@1,COG4085@2	NA|NA|NA	S	PHP domain protein
MAG.T21.18_02994	880073.Calab_3627	1.1e-27	131.3	Bacteria	gnl	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	1.15.1.1,2.7.11.1,3.1.1.17,3.1.1.2,3.1.3.8,3.1.8.1,3.2.1.4,4.3.3.2	ko:K01045,ko:K01053,ko:K01083,ko:K01179,ko:K01757,ko:K02057,ko:K04565,ko:K08884,ko:K13735	ko00030,ko00053,ko00500,ko00562,ko00901,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko04146,ko04213,ko05014,ko05016,ko05020,ko05100,map00030,map00053,map00500,map00562,map00901,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map04146,map04213,map05014,map05016,map05020,map05100	M00129,M00221	R01519,R02933,R03371,R03738,R03751,R06200,R11307,R11308	RC00078,RC00537,RC00983,RC01072,RC01568	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko04147	3.A.1.2	GH5,GH9		Bacteria	COG2374@1,COG2374@2,COG2911@1,COG2911@2,COG3386@1,COG3386@2	NA|NA|NA	S	protein secretion
MAG.T21.18_02995	1459636.NTE_03059	5.1e-11	72.8	Thaumarchaeota													Archaea	41SWG@651137,arCOG07442@1,arCOG07442@2157	NA|NA|NA		
MAG.T21.18_02996	657309.BXY_16270	5.3e-68	264.6	Bacteroidaceae	cysQ		3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130		R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016				Bacteria	2FP00@200643,4AMGH@815,4NFHY@976,COG1218@1,COG1218@2	NA|NA|NA	P	3'(2'),5'-bisphosphate nucleotidase
MAG.T21.18_02997	1356852.N008_16500	1.1e-98	366.7	Cytophagia	ybiK		3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110		R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002				Bacteria	47K5N@768503,4NF1U@976,COG1446@1,COG1446@2	NA|NA|NA	E	PFAM peptidase T2 asparaginase 2
MAG.T21.18_02998	1046627.BZARG_2853	3.4e-59	236.1	Flavobacteriia													Bacteria	1HZM8@117743,4NH1D@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_02999	760192.Halhy_1611	3.6e-69	268.9	Sphingobacteriia													Bacteria	1ISG1@117747,4NFHZ@976,COG0628@1,COG0628@2	NA|NA|NA	S	Pfam:UPF0118
MAG.T21.18_03003	1120968.AUBX01000009_gene246	1.3e-20	105.5	Cytophagia													Bacteria	47S3H@768503,4NUYS@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.18_03004	867900.Celly_1475	7.3e-13	79.7	Cellulophaga				ko:K06872					ko00000				Bacteria	1F9JM@104264,1I3XE@117743,4NS9C@976,COG1512@1,COG1512@2	NA|NA|NA	S	COGs COG1512 Beta-propeller domains of methanol dehydrogenase type
MAG.T21.18_03005	485917.Phep_0677	3.6e-40	171.4	Sphingobacteriia	yyaP		1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000				Bacteria	1IWPD@117747,4NJIQ@976,COG0262@1,COG0262@2	NA|NA|NA	H	bifunctional deaminase-reductase domain protein
MAG.T21.18_03006	1403819.BATR01000066_gene1947	1.2e-44	186.0	Verrucomicrobiae				ko:K07491					ko00000				Bacteria	2IVSQ@203494,46VP6@74201,COG1943@1,COG1943@2	NA|NA|NA	L	Transposase IS200 like
MAG.T21.18_03007	1123248.KB893331_gene3789	1e-79	303.5	Sphingobacteriia	cphB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0042802,GO:0042803,GO:0043170,GO:0044238,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.15.6	ko:K13282			R09722	RC00064,RC00141	ko00000,ko01000,ko01002			iJN678.slr2001	Bacteria	1IREV@117747,4NI55@976,COG4242@1,COG4242@2	NA|NA|NA	PQ	Belongs to the peptidase S51 family
MAG.T21.18_03009	1227739.Hsw_4210	9.7e-41	175.6	Bacteria													Bacteria	COG3391@1,COG3391@2	NA|NA|NA	CO	amine dehydrogenase activity
MAG.T21.18_03013	1123057.P872_14980	2.5e-151	542.3	Cytophagia													Bacteria	47KZC@768503,4NFMV@976,COG1574@1,COG1574@2	NA|NA|NA	S	PFAM Amidohydrolase family
MAG.T21.18_03014	1122605.KB893648_gene3660	3.2e-24	119.8	Sphingobacteriia													Bacteria	1IZ0B@117747,28ICP@1,314Q6@2,4PIZD@976	NA|NA|NA		
MAG.T21.18_03015	755732.Fluta_0875	1.9e-48	199.1	Cryomorphaceae	nifU												Bacteria	1HWKF@117743,2PAXI@246874,4NG0Q@976,COG0694@1,COG0694@2	NA|NA|NA	O	PFAM Scaffold protein Nfu NifU N terminal
MAG.T21.18_03016	926562.Oweho_2865	8.4e-25	120.9	Bacteria				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	COG4206@1,COG4206@2,COG4772@1,COG4772@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.18_03017	1279009.ADICEAN_02557	8.6e-27	127.1	Cytophagia				ko:K03088,ko:K03091					ko00000,ko03021				Bacteria	47P9F@768503,4NNEM@976,COG1595@1,COG1595@2	NA|NA|NA	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family
MAG.T21.18_03018	1408433.JHXV01000047_gene2801	5.8e-16	92.0	Cryomorphaceae				ko:K01999,ko:K08309	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko01000,ko01011,ko02000	3.A.1.4	GH23		Bacteria	1ICSH@117743,2PC00@246874,4PIUE@976,COG1729@1,COG1729@2	NA|NA|NA	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MAG.T21.18_03019	1408433.JHXV01000001_gene671	3.1e-118	431.8	Cryomorphaceae	mrp			ko:K03593					ko00000,ko03029,ko03036				Bacteria	1HWR0@117743,2PA6F@246874,4NF5I@976,COG0489@1,COG0489@2	NA|NA|NA	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MAG.T21.18_03020	391603.FBALC1_07573	8e-79	300.8	Flavobacteriia	holA		2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1HXIE@117743,4NEIB@976,COG1466@1,COG1466@2	NA|NA|NA	L	DNA polymerase III
MAG.T21.18_03021	1123253.AUBD01000010_gene2155	5.6e-101	374.0	Xanthomonadales	amn		2.4.2.3,3.2.2.4	ko:K00757,ko:K01241	ko00230,ko00240,ko00983,ko01100,map00230,map00240,map00983,map01100		R00182,R01876,R02484,R08229	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	1QVR4@1224,1T2HJ@1236,1X3C6@135614,COG2820@1,COG2820@2	NA|NA|NA	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
MAG.T21.18_03022	762982.HMPREF9442_01900	2.1e-34	152.1	Bacteroidia													Bacteria	2FPFZ@200643,4PKFE@976,COG0610@1,COG0610@2	NA|NA|NA	V	type I restriction enzyme
MAG.T21.18_03023	1408433.JHXV01000012_gene3977	1.6e-136	493.8	Cryomorphaceae	cspBA												Bacteria	1I4GV@117743,2PBAJ@246874,4NTWX@976,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
MAG.T21.18_03024	313606.M23134_00430	8e-20	104.8	Bacteroidetes													Bacteria	4NKCW@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.18_03025	1163408.UU9_12678	3.5e-63	248.4	Gammaproteobacteria			2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000				Bacteria	1RAVE@1224,1SYY8@1236,COG0223@1,COG0223@2	NA|NA|NA	J	Formyl transferase
MAG.T21.18_03026	1163409.UUA_02116	3.4e-46	191.4	Gammaproteobacteria													Bacteria	1QEJU@1224,1S598@1236,COG0726@1,COG0726@2	NA|NA|NA	G	Polysaccharide deacetylase
MAG.T21.18_03027	1122176.KB903598_gene4712	1.3e-58	235.7	Bacteria													Bacteria	COG2866@1,COG2866@2	NA|NA|NA	E	metallocarboxypeptidase activity
MAG.T21.18_03030	1237149.C900_05572	3.4e-37	162.5	Cytophagia	cya		4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	47QPA@768503,4NG5A@976,COG2114@1,COG2114@2	NA|NA|NA	T	Adenylate and Guanylate cyclase catalytic domain
MAG.T21.18_03031	755732.Fluta_3989	1.1e-12	81.3	Cryomorphaceae													Bacteria	1IG1J@117743,2ABBW@1,2PBZZ@246874,310SM@2,4PFE8@976	NA|NA|NA		
MAG.T21.18_03032	1237149.C900_00739	5.7e-64	251.5	Cytophagia	cya		4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	47QPA@768503,4NG5A@976,COG2114@1,COG2114@2	NA|NA|NA	T	Adenylate and Guanylate cyclase catalytic domain
MAG.T21.18_03033	697282.Mettu_4065	3.2e-24	117.9	Gammaproteobacteria													Bacteria	1P98F@1224,1SW8T@1236,2E373@1,32ZYW@2	NA|NA|NA		
MAG.T21.18_03035	1408813.AYMG01000027_gene5335	1.6e-77	296.2	Sphingobacteriia	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPC6@117747,4NEYJ@976,COG0294@1,COG0294@2	NA|NA|NA	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MAG.T21.18_03036	1380384.JADN01000006_gene2411	2.6e-60	238.4	Flavobacteriia													Bacteria	1HWSC@117743,28HFG@1,2Z7RJ@2,4NFNY@976	NA|NA|NA	S	Domain of Unknown Function (DUF1599)
MAG.T21.18_03041	1123277.KB893191_gene2897	1.8e-24	120.6	Bacteria													Bacteria	COG2911@1,COG2911@2	NA|NA|NA	S	protein secretion
MAG.T21.18_03042	929703.KE386491_gene4134	2.7e-34	153.3	Bacteroidetes													Bacteria	4PKHZ@976,COG0823@1,COG0823@2,COG5384@1,COG5384@2	NA|NA|NA	J	InterPro IPR003367
MAG.T21.18_03043	1123277.KB893191_gene2895	6.1e-29	135.6	Cytophagia													Bacteria	2DBH5@1,2Z97Q@2,47YKW@768503,4NK7F@976	NA|NA|NA		
MAG.T21.18_03044	1123277.KB893191_gene2895	2.1e-31	143.7	Cytophagia													Bacteria	2DBH5@1,2Z97Q@2,47YKW@768503,4NK7F@976	NA|NA|NA		
MAG.T21.18_03045	1517416.IDAT_03840	8e-21	108.2	Gammaproteobacteria													Bacteria	1QU1E@1224,1T1M0@1236,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha beta hydrolase
MAG.T21.18_03046	1282362.AEAC466_11310	1.4e-260	905.6	Caulobacterales	ptpA_1	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575											Bacteria	1MWGR@1224,2KFZ6@204458,2TUXY@28211,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	peptidase
MAG.T21.18_03049	929713.NIASO_13350	1.6e-49	202.6	Sphingobacteriia	yozB			ko:K07152,ko:K08976					ko00000,ko03029				Bacteria	1ITGM@117747,4NM5N@976,COG2322@1,COG2322@2	NA|NA|NA	S	Protein of unknown function (DUF420)
MAG.T21.18_03050	1408433.JHXV01000001_gene696	5.2e-43	181.4	Cryomorphaceae	ypmQ			ko:K07152,ko:K08976					ko00000,ko03029				Bacteria	1I3NA@117743,2PB1N@246874,4NFH2@976,COG1999@1,COG1999@2	NA|NA|NA	S	SCO1/SenC
MAG.T21.18_03051	755732.Fluta_1918	5.1e-28	130.6	Cryomorphaceae	coxQ												Bacteria	1IC4B@117743,2PB81@246874,4P9DD@976,COG5605@1,COG5605@2	NA|NA|NA	S	Prokaryotic Cytochrome C oxidase subunit IV
MAG.T21.18_03052	755732.Fluta_1919	3.7e-80	305.1	Cryomorphaceae	coxP		1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6			Bacteria	1HWXP@117743,2PAN3@246874,4NDYG@976,COG1845@1,COG1845@2	NA|NA|NA	C	Heme copper-type cytochrome quinol oxidase subunit 3
MAG.T21.18_03053	1202532.FF52_16714	2.4e-21	109.4	Flavobacterium	ctaE		1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6			Bacteria	1I1D8@117743,2NTRK@237,4NFA7@976,COG1845@1,COG1845@2	NA|NA|NA	C	oxidase subunit III
MAG.T21.18_03054	1408433.JHXV01000001_gene701	8.2e-72	277.3	Cryomorphaceae	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029				Bacteria	1HXXM@117743,2PAS3@246874,4NF5A@976,COG0109@1,COG0109@2	NA|NA|NA	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MAG.T21.18_03055	762903.Pedsa_1061	6.7e-231	807.0	Sphingobacteriia	gyrA		5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1IQJH@117747,4NDWQ@976,COG0188@1,COG0188@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAG.T21.18_03056	1408473.JHXO01000007_gene856	6.6e-29	135.2	Bacteroidia				ko:K20543					ko00000,ko02000	1.B.55.3			Bacteria	2G0E9@200643,4P1TE@976,COG4783@1,COG4783@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.18_03057	880526.KE386488_gene1125	3.3e-10	72.4	Rikenellaceae				ko:K03646,ko:K03832					ko00000,ko02000	2.C.1.1,2.C.1.2			Bacteria	22UKT@171550,2G0KV@200643,4NWAV@976,COG0810@1,COG0810@2	NA|NA|NA	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.18_03058	1124780.ANNU01000005_gene2515	2.2e-92	346.3	Cytophagia	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392					ko00000,ko01000,ko03009				Bacteria	47KID@768503,4NEV7@976,COG0144@1,COG0144@2,COG3270@1,COG3270@2	NA|NA|NA	J	RNA-binding PUA-like domain of methyltransferase RsmF
MAG.T21.18_03059	755732.Fluta_2440	9.6e-159	566.6	Cryomorphaceae	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWP1@117743,2PAIG@246874,4NGRZ@976,COG0104@1,COG0104@2	NA|NA|NA	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAG.T21.18_03060	880071.Fleli_4058	1.5e-11	75.9	Cytophagia	rsbV			ko:K04749,ko:K06378					ko00000,ko03021				Bacteria	47R73@768503,4NTNE@976,COG1366@1,COG1366@2	NA|NA|NA	T	Belongs to the anti-sigma-factor antagonist family
MAG.T21.18_03062	927658.AJUM01000034_gene567	8.5e-59	235.0	Bacteroidetes													Bacteria	29X8I@1,30IXV@2,4P0MB@976	NA|NA|NA		
MAG.T21.18_03063	1341155.FSS13T_21560	1.3e-66	260.4	Bacteroidetes													Bacteria	4NQ4R@976,COG0535@1,COG0535@2	NA|NA|NA	C	4Fe-4S single cluster domain
MAG.T21.18_03064	1121904.ARBP01000001_gene5647	2.9e-137	495.0	Cytophagia	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47KXJ@768503,4NIE0@976,COG1013@1,COG1013@2	NA|NA|NA	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
MAG.T21.18_03065	1121904.ARBP01000001_gene5646	2.1e-133	482.3	Cytophagia	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47KM5@768503,4NEP3@976,COG0674@1,COG0674@2,COG1014@1,COG1014@2	NA|NA|NA	C	Pyruvate ferredoxin/flavodoxin oxidoreductase
MAG.T21.18_03066	680646.RMDY18_00050	5.8e-30	138.7	Actinobacteria													Bacteria	2DXS1@1,2HAC0@201174,32V40@2	NA|NA|NA		
MAG.T21.18_03067	755732.Fluta_1586	1.5e-61	244.2	Cryomorphaceae													Bacteria	1HXIR@117743,2PB19@246874,4PKTX@976,COG4773@1,COG4773@2	NA|NA|NA	P	Receptor
MAG.T21.18_03068	1408473.JHXO01000011_gene3152	1.2e-151	544.3	Bacteroidia													Bacteria	2FM3C@200643,4NE4W@976,COG0457@1,COG0457@2,COG1729@1,COG1729@2	NA|NA|NA	G	Tetratricopeptide repeat protein
MAG.T21.18_03069	1408433.JHXV01000001_gene706	2.1e-56	225.3	Flavobacteriia	gmd		4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100		R00888	RC00402	ko00000,ko00001,ko01000				Bacteria	1HY1Q@117743,4NEB6@976,COG1089@1,COG1089@2	NA|NA|NA	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MAG.T21.18_03070	1123277.KB893193_gene3895	4.3e-140	504.2	Cytophagia	fcl		1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100		R05692	RC01014	ko00000,ko00001,ko01000				Bacteria	47KAF@768503,4NDV4@976,COG0451@1,COG0451@2	NA|NA|NA	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
MAG.T21.18_03071	929556.Solca_4329	6.2e-51	208.8	Sphingobacteriia													Bacteria	1IQA3@117747,2DBCF@1,2Z8DB@2,4NG6B@976	NA|NA|NA		
MAG.T21.18_03072	1408433.JHXV01000001_gene703	8.6e-95	354.0	Cryomorphaceae	wecA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008963,GO:0009058,GO:0009059,GO:0009103,GO:0009246,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046378,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.8.33,2.7.8.35,5.1.3.14	ko:K01791,ko:K02851	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R08856	RC00002,RC00290	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005			iAF987.Gmet_1505,iECSF_1327.ECSF_3624	Bacteria	1HZEV@117743,2PC5X@246874,4NGKM@976,COG0472@1,COG0472@2	NA|NA|NA	M	Glycosyl transferase family 4
MAG.T21.18_03073	153721.MYP_1295	8.2e-78	298.1	Cytophagia													Bacteria	2DBCF@1,2Z8DB@2,47NKW@768503,4NG6B@976	NA|NA|NA		
MAG.T21.18_03080	1121896.JMLU01000016_gene1710	2.1e-07	62.8	Flavobacterium													Bacteria	1IDAB@117743,2ECI3@1,2NXVI@237,30Z6H@2,4NXXS@976	NA|NA|NA		
MAG.T21.18_03081	301.JNHE01000018_gene3868	3.1e-42	179.1	Pseudomonas aeruginosa group													Bacteria	1N40I@1224,1S1R3@1236,1YIGG@136841,COG4714@1,COG4714@2	NA|NA|NA	S	Protein of unknown function (DUF2167)
MAG.T21.18_03082	700598.Niako_7023	6.2e-187	660.6	Sphingobacteriia	ade	GO:0000034,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0006040,GO:0006044,GO:0006046,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008448,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016787,GO:0016810,GO:0016811,GO:0016814,GO:0018130,GO:0019213,GO:0019239,GO:0019438,GO:0019439,GO:0030145,GO:0034641,GO:0042221,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046348,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070887,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0097237,GO:0098754,GO:0098869,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1990748	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100		R01244	RC00477	ko00000,ko00001,ko01000			iECUMN_1333.ECUMN_4192,iSFV_1184.SFV_3844,iYO844.BSU14520	Bacteria	1IQD0@117747,4NFD9@976,COG1001@1,COG1001@2	NA|NA|NA	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MAG.T21.18_03084	926556.Echvi_2874	9.2e-49	200.7	Cytophagia	gluQ		6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016				Bacteria	47Q0Q@768503,4NP0Y@976,COG0008@1,COG0008@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
MAG.T21.18_03089	1089549.AZUQ01000001_gene1559	5.4e-29	133.3	Glycomycetales	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K07456	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	2I4QA@201174,4EYUQ@85014,COG1193@1,COG1193@2	NA|NA|NA	L	Smr domain
MAG.T21.18_03090	649349.Lbys_1223	7.4e-19	99.8	Cytophagia	yjdJ			ko:K06975					ko00000				Bacteria	47RZM@768503,4NUS6@976,COG2388@1,COG2388@2	NA|NA|NA	S	GCN5-related N-acetyl-transferase
MAG.T21.18_03091	1476583.DEIPH_ctg025orf0105	2.2e-64	252.3	Bacteria			2.1.1.113,2.1.1.72	ko:K00590,ko:K07319					ko00000,ko01000,ko02048				Bacteria	COG2521@1,COG2521@2	NA|NA|NA	AJ	methyltransferase
MAG.T21.18_03092	700598.Niako_0956	1.5e-26	125.9	Sphingobacteriia													Bacteria	1IT22@117747,4NP44@976,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
MAG.T21.18_03093	128390.XP_009465617.1	1.2e-08	65.1	Aves	MUT	GO:0000096,GO:0003674,GO:0003824,GO:0003924,GO:0004494,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009235,GO:0009791,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017111,GO:0017144,GO:0019752,GO:0019842,GO:0031419,GO:0031974,GO:0032501,GO:0032502,GO:0033013,GO:0036094,GO:0042802,GO:0042803,GO:0043085,GO:0043087,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043547,GO:0044093,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046906,GO:0046983,GO:0048037,GO:0048856,GO:0050667,GO:0050790,GO:0051186,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901605	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000				Metazoa	2QQ7X@2759,38HNY@33154,3BABU@33208,3CTUG@33213,482MI@7711,4904P@7742,4GQZW@8782,COG1884@1	NA|NA|NA	I	methylmalonyl-CoA mutase, mitochondrial
MAG.T21.18_03095	1499967.BAYZ01000148_gene1724	1.8e-10	71.6	unclassified Bacteria													Bacteria	2C5EY@1,2NREI@2323,32YQJ@2	NA|NA|NA	S	Evidence 4 Homologs of previously reported genes of
MAG.T21.18_03096	761193.Runsl_5646	4.4e-212	744.2	Cytophagia	mutB		5.4.99.13,5.4.99.2	ko:K01847,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000				Bacteria	47JW5@768503,4NFS0@976,COG1884@1,COG1884@2,COG2185@1,COG2185@2	NA|NA|NA	I	Methylmalonyl-CoA mutase
MAG.T21.18_03098	385682.AFSL01000064_gene1700	7.3e-88	330.5	Marinilabiliaceae													Bacteria	2FQJ1@200643,3XJXP@558415,4NE0J@976,COG0501@1,COG0501@2	NA|NA|NA	O	Peptidase family M48
MAG.T21.18_03099	391598.FBBAL38_12625	3.2e-22	110.9	Flavobacteriia	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087		ko:K06891					ko00000				Bacteria	1I3WR@117743,4NS8R@976,COG2127@1,COG2127@2	NA|NA|NA	S	Belongs to the ClpS family
MAG.T21.18_03100	1408433.JHXV01000033_gene1155	3.1e-48	200.7	Cryomorphaceae	ftsK		2.1.1.72	ko:K03427,ko:K03466,ko:K03546,ko:K19171					ko00000,ko01000,ko02048,ko03036,ko03400	3.A.12			Bacteria	1ICPT@117743,2PBJT@246874,4PP0U@976,COG0419@1,COG0419@2,COG1196@1,COG1196@2,COG3391@1,COG3391@2	NA|NA|NA	DL	nuclear chromosome segregation
MAG.T21.18_03103	1121957.ATVL01000010_gene235	3.9e-18	97.4	Cytophagia	paaN	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.2.1.77,1.2.1.91,3.3.2.12	ko:K02618,ko:K15514	ko00360,ko00362,ko01120,map00360,map00362,map01120		R09554,R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000			iEC55989_1330.EC55989_1523,iECO111_1330.ECO111_1781,iECO26_1355.ECO26_1991	Bacteria	47UEK@768503,4NI68@976,COG1012@1,COG1012@2,COG2030@1,COG2030@2	NA|NA|NA	CI	MaoC like domain
MAG.T21.18_03104	1469557.JSWF01000014_gene2525	1.5e-52	213.8	Flavobacteriia													Bacteria	1I0CF@117743,4NM0P@976,COG3291@1,COG3291@2	NA|NA|NA	M	PFAM PKD domain
MAG.T21.18_03105	926562.Oweho_0543	2e-31	141.4	Cryomorphaceae			4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYQY@117743,2PBN1@246874,4NEVN@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2	NA|NA|NA	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family
MAG.T21.18_03106	421072.IO89_14255	9.4e-77	293.1	Chryseobacterium				ko:K03316					ko00000	2.A.36			Bacteria	1HXPI@117743,3HH9F@358033,4NFHG@976,COG0025@1,COG0025@2	NA|NA|NA	P	Sodium/hydrogen exchanger family
MAG.T21.18_03107	1233951.IO90_13965	1.9e-96	359.4	Chryseobacterium				ko:K03316					ko00000	2.A.36			Bacteria	1HXPI@117743,3HH9F@358033,4NFHG@976,COG0025@1,COG0025@2	NA|NA|NA	P	Sodium/hydrogen exchanger family
MAG.T21.18_03109	290317.Cpha266_1975	1.9e-12	79.0	Bacteria													Bacteria	2ESXY@1,33KG8@2	NA|NA|NA		
MAG.T21.18_03110	1185876.BN8_06440	3.7e-205	721.8	Cytophagia	pacL		3.6.3.8	ko:K01537					ko00000,ko01000	3.A.3.2			Bacteria	47JYI@768503,4NERM@976,COG0474@1,COG0474@2	NA|NA|NA	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC
MAG.T21.18_03111	468059.AUHA01000005_gene2433	2.5e-48	198.4	Sphingobacteriia													Bacteria	1J0JE@117747,4NHXI@976,COG1327@1,COG1327@2	NA|NA|NA	K	Restriction endonuclease
MAG.T21.18_03114	1239962.C943_00813	2.6e-74	285.0	Cytophagia	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147			iUTI89_1310.UTI89_C4836,ic_1306.c5329	Bacteria	47KNQ@768503,4NG06@976,COG0158@1,COG0158@2	NA|NA|NA	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MAG.T21.18_03115	1122621.ATZA01000008_gene884	2.2e-142	512.7	Sphingobacteriia	dnaX		2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IQ35@117747,4NE8A@976,COG2812@1,COG2812@2	NA|NA|NA	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAG.T21.18_03116	1122176.KB903598_gene4712	3.5e-87	329.3	Bacteria													Bacteria	COG2866@1,COG2866@2	NA|NA|NA	E	metallocarboxypeptidase activity
MAG.T21.18_03118	468059.AUHA01000002_gene1303	2e-177	628.6	Sphingobacteriia	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02355					ko00000,ko03012,ko03029				Bacteria	1INUJ@117747,4NE9X@976,COG0480@1,COG0480@2	NA|NA|NA	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAG.T21.18_03119	755732.Fluta_0780	1.9e-44	184.9	Cryomorphaceae	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141		ko:K02946	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I2VK@117743,2PAXU@246874,4NQ65@976,COG0051@1,COG0051@2	NA|NA|NA	J	Involved in the binding of tRNA to the ribosomes
MAG.T21.18_03122	1519464.HY22_07700	3.2e-53	215.3	Bacteria	Z012_00180		3.1.1.5	ko:K10804	ko01040,map01040				ko00000,ko00001,ko01000,ko01004				Bacteria	COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
MAG.T21.18_03123	1168034.FH5T_04200	6e-65	253.8	Bacteroidia	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141		ko:K02601					ko00000,ko03009,ko03021				Bacteria	2FNJ6@200643,4NF2X@976,COG0250@1,COG0250@2	NA|NA|NA	K	Participates in transcription elongation, termination and antitermination
MAG.T21.18_03124	1408433.JHXV01000007_gene2900	1.1e-15	89.0	Cryomorphaceae	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1IC4N@117743,2PB91@246874,4PFHS@976,COG0690@1,COG0690@2	NA|NA|NA	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MAG.T21.18_03126	755732.Fluta_2153	1.1e-114	419.5	Cryomorphaceae	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484		ko:K02358,ko:K15771	ko02010,map02010	M00491			ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2		iSB619.SA_RS02960	Bacteria	1HWMU@117743,2PA6H@246874,4NEWS@976,COG0050@1,COG0050@2	NA|NA|NA	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAG.T21.18_03127	1123276.KB893311_gene3164	2.9e-08	64.3	Cytophagia													Bacteria	47URK@768503,4NRDG@976,COG4244@1,COG4244@2	NA|NA|NA	S	Membrane
MAG.T21.18_03128	1122621.ATZA01000029_gene2758	3.5e-64	251.5	Sphingobacteriia	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564		ko:K03694,ko:K03695	ko04213,map04213				ko00000,ko00001,ko03110				Bacteria	1IQP6@117747,4NGEM@976,COG0542@1,COG0542@2	NA|NA|NA	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAG.T21.18_03129	1470593.BW43_02852	3.6e-23	115.5	Bacteria													Bacteria	2EJ0Q@1,33CRW@2	NA|NA|NA		
MAG.T21.18_03130	525373.HMPREF0766_12286	2.6e-43	181.8	Sphingobacteriia	accB		2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1			Bacteria	1ISET@117747,4NM8U@976,COG0511@1,COG0511@2	NA|NA|NA	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MAG.T21.18_03131	1454007.JAUG01000001_gene3696	4.2e-51	207.2	Sphingobacteriia	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IPRR@117747,4NEYH@976,COG0332@1,COG0332@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAG.T21.18_03132	1123501.KB902293_gene3465	1.5e-29	135.6	Alphaproteobacteria	recQ		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	1MVGG@1224,2TS8B@28211,COG0514@1,COG0514@2	NA|NA|NA	L	DNA helicase
MAG.T21.18_03133	1353537.TP2_05720	4.6e-140	504.6	Thioclava	gacS		2.7.13.3	ko:K07678,ko:K11527	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1R5EN@1224,2TZRB@28211,2XKXQ@285107,COG0642@1,COG0642@2,COG5002@1,COG5002@2	NA|NA|NA	T	PAS fold
MAG.T21.18_03134	118168.MC7420_7019	1.4e-34	153.7	Bacteria				ko:K14645	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	COG1404@1,COG1404@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.18_03140	1408433.JHXV01000014_gene3654	1.6e-40	172.9	Cryomorphaceae				ko:K17230	ko00920,ko01120,map00920,map01120		R09499		ko00000,ko00001				Bacteria	1IG0F@117743,2PB3U@246874,4NKQI@976,COG2010@1,COG2010@2,COG2885@1,COG2885@2	NA|NA|NA	C	Cytochrome C oxidase, cbb3-type, subunit III
MAG.T21.18_03141	755732.Fluta_1181	1.2e-62	246.1	Cryomorphaceae	actD												Bacteria	1HXN6@117743,2PAX8@246874,4NEX9@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF3341)
MAG.T21.18_03147	929556.Solca_0226	3.4e-78	297.7	Sphingobacteriia	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	1INW2@117747,4NEXT@976,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAG.T21.18_03148	643867.Ftrac_3323	3.6e-20	105.1	Cytophagia													Bacteria	47YDS@768503,4PNPU@976,COG2353@1,COG2353@2	NA|NA|NA	S	YceI-like domain
MAG.T21.18_03151	1229780.BN381_210087	1.7e-38	165.2	unclassified Actinobacteria (class)	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100		R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000				Bacteria	2GIVK@201174,3UWF9@52018,COG0520@1,COG0520@2	NA|NA|NA	E	Aminotransferase class-V
MAG.T21.18_03153	929562.Emtol_3010	1e-07	63.2	Cytophagia													Bacteria	47TYA@768503,4PPBJ@976,COG0823@1,COG0823@2,COG1361@1,COG1361@2,COG2373@1,COG2373@2	NA|NA|NA	M	Conserved repeat domain
# 2627 queries scanned
# Total time (seconds): 26.8657829762
# Rate: 97.78 q/s