# emapper version: emapper-hotfix-numpy-69-gdd722db emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/emapper//MAG.T12.39/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/Bin_prokka//MAG.T12.39/MAG.T12.39.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share3/Bin_all/emapper//MAG.T12.39/MAG.T12.39 --usemem --override # time: Fri Aug 21 04:24:32 2026 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. MAG.T12.39_00001 1292034.OR37_02035 3.6e-81 308.5 Caulobacterales corA GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 iAF987.Gmet_0134,iYL1228.KPN_04313 Bacteria 1MWMP@1224,2KGHK@204458,2TQQD@28211,COG0598@1,COG0598@2 NA|NA|NA P PFAM Mg2 transporter protein CorA family protein MAG.T12.39_00002 450851.PHZ_c3330 1.1e-76 293.1 Caulobacterales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1N0K8@1224,2KGHY@204458,2UDGN@28211,COG3942@1,COG3942@2 NA|NA|NA S PFAM CHAP domain containing protein MAG.T12.39_00003 1229204.AMYY01000027_gene1742 3.3e-93 348.2 unclassified Alphaproteobacteria terC Bacteria 1MWC9@1224,2TTT6@28211,4BQ37@82117,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family MAG.T12.39_00004 450851.PHZ_c3332 0.0 1077.0 Caulobacterales priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUUZ@1224,2KEXZ@204458,2TQTQ@28211,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA MAG.T12.39_00005 450851.PHZ_c3333 2.3e-95 355.1 Caulobacterales tal 1.1.1.343,1.1.1.44,2.2.1.2 ko:K00033,ko:K00616 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00006,M00007 R01528,R01827,R10221 RC00001,RC00439,RC00539,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWQ8@1224,2KFGI@204458,2TQJB@28211,COG0176@1,COG0176@2 NA|NA|NA F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway MAG.T12.39_00006 1449049.JONW01000006_gene2966 8.9e-39 167.2 Caulobacterales yigA ko:K09921 ko00000 Bacteria 1PSS8@1224,2KGK8@204458,2V4V4@28211,COG3159@1,COG3159@2 NA|NA|NA S Protein of unknown function, DUF484 MAG.T12.39_00007 450851.PHZ_c3335 1.5e-124 452.6 Caulobacterales xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1QU6A@1224,2KFYX@204458,2TS7W@28211,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T12.39_00008 1446473.JHWH01000029_gene2129 9.6e-21 107.5 Alphaproteobacteria ko:K03286,ko:K12976,ko:K16079 ko00000,ko01000,ko01005,ko02000 1.B.4.2.1,1.B.6 Bacteria 1R94P@1224,2U4PW@28211,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T12.39_00009 450851.PHZ_c3337 7.7e-210 736.5 Caulobacterales lpd3 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU2U@1224,2KG5Y@204458,2TRN7@28211,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase MAG.T12.39_00010 1292034.OR37_02048 2.8e-152 545.0 Caulobacterales sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 Bacteria 1MUJD@1224,2KFE3@204458,2TS5N@28211,COG0508@1,COG0508@2 NA|NA|NA C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) MAG.T12.39_00011 1449049.JONW01000006_gene2956 0.0 1576.2 Caulobacterales sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 1MVBF@1224,2KFCE@204458,2TRBQ@28211,COG0567@1,COG0567@2 NA|NA|NA C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate MAG.T12.39_00012 450851.PHZ_c0159 5.6e-150 537.0 Caulobacterales sucD 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUGA@1224,2KFBH@204458,2TQKB@28211,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit MAG.T12.39_00013 450851.PHZ_c0158 6.7e-194 683.3 Caulobacterales sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVCE@1224,2KEYZ@204458,2TRXK@28211,COG0045@1,COG0045@2 NA|NA|NA F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit MAG.T12.39_00014 69395.JQLZ01000006_gene2128 1.8e-37 162.5 Caulobacterales Bacteria 1N0CF@1224,2KGXU@204458,2UC5R@28211,COG5395@1,COG5395@2 NA|NA|NA S Predicted membrane protein (DUF2306) MAG.T12.39_00015 190650.CC_0330 1e-49 203.8 Caulobacterales lytT ko:K02477,ko:K07705 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko02022 Bacteria 1N903@1224,2KGNN@204458,2U7W7@28211,COG3279@1,COG3279@2 NA|NA|NA KT LytTr DNA-binding domain MAG.T12.39_00016 450851.PHZ_c0152 1.4e-152 545.8 Caulobacterales mdh GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV57@1224,2KEZF@204458,2TSV6@28211,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate MAG.T12.39_00017 450851.PHZ_c0151 6.3e-44 183.7 Caulobacterales MA20_21960 Bacteria 1MZVD@1224,2KHF5@204458,2UC00@28211,COG0537@1,COG0537@2 NA|NA|NA FG PFAM histidine triad (HIT) protein MAG.T12.39_00018 509190.Cseg_4150 6e-16 91.3 Caulobacterales Bacteria 1P95J@1224,2DDC2@1,2KJP1@204458,2UWDH@28211,2ZHGE@2 NA|NA|NA MAG.T12.39_00019 1382303.JPOM01000001_gene1449 8.9e-84 317.0 Caulobacterales citE 3.1.2.30,4.1.3.25,4.1.3.34 ko:K01644,ko:K14451,ko:K18292 ko00630,ko00660,ko01100,ko01120,ko01200,ko02020,map00630,map00660,map01100,map01120,map01200,map02020 M00373 R00237,R00362,R10612 RC00004,RC00014,RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0A@1224,2KG0Q@204458,2TTC0@28211,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family MAG.T12.39_00020 450851.PHZ_c0149 2.9e-50 204.5 Caulobacterales ko:K09966 ko00000 Bacteria 1RH68@1224,2KINW@204458,2U9D3@28211,COG3651@1,COG3651@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2237) MAG.T12.39_00021 450851.PHZ_c3338 5.2e-109 401.0 Caulobacterales fieF GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874 ko:K13283 ko00000,ko02000 2.A.4.7.1 Bacteria 1MUDS@1224,2KG2B@204458,2TT78@28211,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family MAG.T12.39_00022 190650.CC_3639 3.2e-97 361.3 Caulobacterales gst 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1MXM4@1224,2KG34@204458,2TTXD@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase MAG.T12.39_00023 450851.PHZ_c3340 1.1e-145 523.1 Caulobacterales queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1MV1H@1224,2KFPP@204458,2TR5E@28211,COG1600@1,COG1600@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) MAG.T12.39_00024 450851.PHZ_c1130 9.5e-104 383.3 Caulobacterales MA20_16345 Bacteria 1PJ4R@1224,2KIC2@204458,2TSSU@28211,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_00025 450851.PHZ_c1129 1.1e-92 346.7 Alphaproteobacteria 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1P71B@1224,2U1A5@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase MAG.T12.39_00026 402881.Plav_2850 3.3e-91 341.7 Rhodobiaceae tesB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1JMZB@119043,1MV9R@1224,2TRFD@28211,COG1946@1,COG1946@2 NA|NA|NA I Thioesterase-like superfamily MAG.T12.39_00027 450851.PHZ_c3341 9.6e-79 299.7 Caulobacterales rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1R9YD@1224,2KGN5@204458,2U7G8@28211,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose MAG.T12.39_00028 366602.Caul_4940 2.8e-92 345.5 Caulobacterales wbbL_2 ko:K07011 ko00000 Bacteria 1R6SJ@1224,2KFG0@204458,2U47V@28211,COG1216@1,COG1216@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T12.39_00029 450851.PHZ_c3344 1.5e-46 192.6 Caulobacterales 5.2.1.8 ko:K01802,ko:K03773 ko00000,ko01000,ko03110 Bacteria 1RDA1@1224,2KK30@204458,2U9XK@28211,COG0545@1,COG0545@2 NA|NA|NA M Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MAG.T12.39_00030 450851.PHZ_c3345 3.3e-177 627.9 Caulobacterales ilvA 1.1.1.3,1.1.1.399,1.1.1.95,2.7.6.5,3.1.7.2,4.3.1.19 ko:K00003,ko:K00058,ko:K01139,ko:K01754 ko00230,ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00336,R00429,R00996,R01513,R01773,R01775 RC00002,RC00031,RC00078,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 iLJ478.TM0356 Bacteria 1MVWJ@1224,2KF3J@204458,2TQN9@28211,COG0317@1,COG0317@2,COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA MAG.T12.39_00031 1161401.ASJA01000017_gene1294 9.7e-213 746.5 Bacteria ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria COG1123@1,COG4172@2 NA|NA|NA P ATPase activity MAG.T12.39_00032 450851.PHZ_c3346 2.5e-65 255.0 Caulobacterales gmhB 2.7.7.71,3.1.3.82,3.1.3.83 ko:K03273,ko:K15669 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771,R09772 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1RDGR@1224,2KG4X@204458,2TRW1@28211,COG0241@1,COG0241@2 NA|NA|NA E D,D-heptose 1,7-bisphosphate phosphatase MAG.T12.39_00033 450851.PHZ_c3349 2.7e-39 168.3 Caulobacterales MA20_04725 ko:K02614 ko00360,map00360 R09840 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1RHK6@1224,2KH0A@204458,2U72Z@28211,COG2050@1,COG2050@2 NA|NA|NA Q thioesterase MAG.T12.39_00034 1449049.JONW01000005_gene1896 1.1e-44 186.0 Caulobacterales yigI Bacteria 1RITB@1224,2KGZU@204458,2U58S@28211,COG2050@1,COG2050@2 NA|NA|NA Q PFAM thioesterase superfamily MAG.T12.39_00035 450851.PHZ_c3351 7.2e-109 400.6 Caulobacterales ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1MXD8@1224,2KG73@204458,2TQMQ@28211,COG3221@1,COG3221@2 NA|NA|NA P phosphonate ABC transporter, periplasmic MAG.T12.39_00036 450851.PHZ_c3352 2.7e-257 894.4 Caulobacterales lysS 6.1.1.6 ko:K04566 ko00970,map00970 M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV32@1224,2KF89@204458,2TQYH@28211,COG1384@1,COG1384@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T12.39_00037 450851.PHZ_c0446 5e-214 750.7 Caulobacterales 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUV6@1224,2KFS8@204458,2TR49@28211,COG0405@1,COG0405@2 NA|NA|NA M gamma-glutamyltransferase MAG.T12.39_00038 450851.PHZ_c0447 1.5e-136 492.7 Caulobacterales dmpA 3.4.11.19 ko:K01266 ko00000,ko01000,ko01002 Bacteria 1MWDP@1224,2KFJX@204458,2TRDC@28211,COG3191@1,COG3191@2 NA|NA|NA EQ Peptidase family S58 MAG.T12.39_00040 1211114.ALIP01000012_gene1405 4.1e-119 434.9 Xanthomonadales Bacteria 1MV69@1224,1RRCR@1236,1X5H9@135614,COG3177@1,COG3177@2 NA|NA|NA S Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins MAG.T12.39_00042 1449049.JONW01000006_gene2704 3.1e-19 100.9 Bacteria Bacteria 2C4HP@1,33HN5@2 NA|NA|NA MAG.T12.39_00043 235985.BBPN01000036_gene643 4.9e-26 124.4 Streptacidiphilus cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974,ko:K07276,ko:K19545 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko01504,ko03016,ko03019 Bacteria 2IFKR@201174,2NIQF@228398,COG0617@1,COG0617@2 NA|NA|NA J Aminoglycoside-2''-adenylyltransferase MAG.T12.39_00046 391600.ABRU01000056_gene520 2.8e-75 288.5 Caulobacterales Bacteria 1MUZE@1224,2KF5S@204458,2TT6M@28211,COG1814@1,COG1814@2 NA|NA|NA S VIT family MAG.T12.39_00047 450851.PHZ_c2807 1.3e-12 78.2 Caulobacterales ccoS Bacteria 1PUQW@1224,2KHFC@204458,2VATU@28211,COG3197@1,COG3197@2 NA|NA|NA P cytochrome oxidase maturation protein cbb3-type MAG.T12.39_00048 450851.PHZ_c2808 3.9e-248 864.4 Caulobacterales ccoI 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1MU08@1224,2KEZ4@204458,2TR80@28211,COG2217@1,COG2217@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T12.39_00049 450851.PHZ_c2809 1.2e-43 183.0 Caulobacterales fixH Bacteria 1Q37U@1224,2KH73@204458,2VA6V@28211,COG5456@1,COG5456@2 NA|NA|NA P PFAM FixH family protein MAG.T12.39_00050 450851.PHZ_c2810 3.6e-189 667.9 Caulobacterales ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MVFY@1224,2KFHG@204458,2TRYB@28211,COG0348@1,COG0348@2 NA|NA|NA C Cytochrome c oxidase accessory protein MAG.T12.39_00051 190650.CC_1404 5.3e-116 424.1 Caulobacterales ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1MUCW@1224,2KG0I@204458,2TQW1@28211,COG2010@1,COG2010@2 NA|NA|NA C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex MAG.T12.39_00052 633149.Bresu_2097 8.2e-16 89.0 Caulobacterales ccoQ ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1NGV0@1224,2KJJM@204458,2UJBS@28211,COG4736@1,COG4736@2 NA|NA|NA O PFAM Cbb3-type cytochrome oxidase component MAG.T12.39_00053 1292034.OR37_02845 1.8e-104 385.6 Caulobacterales ccoO 1.9.3.1 ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0145 Bacteria 1MXEY@1224,2KFH7@204458,2TRGW@28211,COG2993@1,COG2993@2 NA|NA|NA C TIGRFAM cytochrome c oxidase, cbb3-type, subunit II MAG.T12.39_00054 633149.Bresu_2095 5.6e-260 903.3 Caulobacterales ccoN 1.9.3.1 ko:K00404,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144 Bacteria 1MU18@1224,2KFC3@204458,2TR2C@28211,COG3278@1,COG3278@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T12.39_00057 1449049.JONW01000002_gene2420 9e-260 902.9 Caulobacterales Bacteria 1MUJ3@1224,2KGA1@204458,2U3RR@28211,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase family MAG.T12.39_00058 450851.PHZ_c1999 8.4e-159 567.0 Caulobacterales gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,2KFFS@204458,2TQR1@28211,COG1012@1,COG1012@2 NA|NA|NA C belongs to the aldehyde dehydrogenase family MAG.T12.39_00059 450851.PHZ_c0473 1.3e-187 662.9 Caulobacterales wxcD Bacteria 1NPA5@1224,2KHRJ@204458,2TSGM@28211,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T12.39_00060 1382303.JPOM01000001_gene422 4.2e-80 304.7 Caulobacterales iphP 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1R4XF@1224,2KGDH@204458,2U0KA@28211,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family MAG.T12.39_00061 1161401.ASJA01000002_gene2575 1.9e-33 149.8 Hyphomonadaceae 1.14.13.238 ko:K22342 ko00000,ko01000 Bacteria 1N6CK@1224,2DB9X@1,2U2ME@28211,2Z7ZS@2,43XMS@69657 NA|NA|NA S Protein of unknown function (DUF3445) MAG.T12.39_00062 450851.PHZ_c0076 1.6e-85 322.4 Caulobacterales MA20_23095 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 ko:K07025 ko00000 Bacteria 1Q69X@1224,2KF6K@204458,2TTTP@28211,COG1011@1,COG1011@2 NA|NA|NA S subfamily IA, variant 3 MAG.T12.39_00063 450851.PHZ_c0077 1.1e-28 132.5 Caulobacterales phhB 4.2.1.96 ko:K01724 ko00790,map00790 R04734 RC01208 ko00000,ko00001,ko01000,ko04147 Bacteria 1MZ5Q@1224,2KH11@204458,2UBWN@28211,COG2154@1,COG2154@2 NA|NA|NA H pterin-4-alpha-carbinolamine dehydratase MAG.T12.39_00064 1229204.AMYY01000024_gene2920 7.1e-18 97.1 Alphaproteobacteria Bacteria 1N7PH@1224,2E8W9@1,2UI6X@28211,3336G@2 NA|NA|NA MAG.T12.39_00065 450851.PHZ_c0080 7.9e-143 513.5 Caulobacterales pseB 4.2.1.115 ko:K13013,ko:K15894 ko00520,map00520 R09697 RC02609 ko00000,ko00001,ko01000,ko01005 Bacteria 1MWKY@1224,2KFU2@204458,2TT4K@28211,COG1086@1,COG1086@2 NA|NA|NA N Flagellin modification protein FlmA MAG.T12.39_00066 450851.PHZ_c0081 3.8e-146 524.6 Caulobacterales pseC 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1MUPN@1224,2KF7K@204458,2TRIQ@28211,COG0399@1,COG0399@2 NA|NA|NA M Belongs to the DegT DnrJ EryC1 family MAG.T12.39_00067 450851.PHZ_c0083 3.7e-112 411.0 Caulobacterales Bacteria 1MVCB@1224,2KFT7@204458,2TR43@28211,COG0745@1,COG0745@2 NA|NA|NA K Two component transcriptional regulator, winged helix family MAG.T12.39_00068 450851.PHZ_c0084 1.3e-165 589.7 Caulobacterales chvG 2.7.13.3 ko:K14980 ko02020,map02020 M00520 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1QU7C@1224,2KFU6@204458,2TWBW@28211,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase MAG.T12.39_00069 1292034.OR37_03881 9.8e-35 153.3 Caulobacterales hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1NNN5@1224,2KH6M@204458,2UFPB@28211,COG1493@1,COG1493@2 NA|NA|NA T PFAM HPr serine kinase MAG.T12.39_00070 69395.JQLZ01000004_gene836 1.1e-55 222.6 Caulobacterales manX 2.7.1.191,2.7.1.194 ko:K02793,ko:K02794,ko:K02821 ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060 M00276,M00283,M00550 R02630,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.7.1 Bacteria 1RHH7@1224,2KGF3@204458,2U9E5@28211,COG2893@1,COG2893@2 NA|NA|NA G PFAM PTS system fructose subfamily IIA component MAG.T12.39_00071 450851.PHZ_c0087 1.2e-29 135.6 Caulobacterales ptsO GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 2.7.1.121 ko:K05881,ko:K08485,ko:K11189 ko00561,ko02060,map00561,map02060 R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 4.A.2.1 Bacteria 1N6RM@1224,2KHC3@204458,2UC0H@28211,COG1925@1,COG1925@2 NA|NA|NA G TIGRFAM phosphocarrier, HPr family MAG.T12.39_00072 190650.CC_3522 5.3e-41 175.6 Alphaproteobacteria ygiF 3.6.1.25,4.6.1.1 ko:K01768,ko:K18446 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY43@1224,2TQRV@28211,COG3025@1,COG3025@2,COG5607@1,COG5607@2 NA|NA|NA S PFAM CHAD domain containing protein MAG.T12.39_00073 588932.JHOF01000001_gene455 4.3e-245 853.6 Caulobacterales ahcY GO:0000096,GO:0000097,GO:0000098,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0035375,GO:0035635,GO:0036094,GO:0036293,GO:0040007,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0070482,GO:0071268,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 1MUQ2@1224,2KF3V@204458,2TSJY@28211,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine MAG.T12.39_00074 1449049.JONW01000005_gene1792 1.4e-54 219.9 Caulobacterales pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MVC9@1224,2KGNA@204458,2U2CH@28211,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase MAG.T12.39_00075 288000.BBta_7675 7.7e-169 600.1 Bradyrhizobiaceae MA20_23445 1.14.13.107 ko:K14733 ko00903,map00903 R06398,R09385,R09389,R09393 RC01506 ko00000,ko00001,ko01000 Bacteria 1NKS6@1224,2TT87@28211,3JRJ6@41294,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase MAG.T12.39_00076 450851.PHZ_c0098 4e-98 364.8 Caulobacterales rarD ko:K05786 ko00000,ko02000 2.A.7.7 Bacteria 1MX5G@1224,2KG4P@204458,2TV8D@28211,COG2962@1,COG2962@2 NA|NA|NA S TIGRFAM RarD protein, DMT superfamily transporter MAG.T12.39_00077 450851.PHZ_c0099 6.7e-171 606.7 Caulobacterales asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1523 Bacteria 1MUHG@1224,2KF5P@204458,2TSRD@28211,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate MAG.T12.39_00078 450851.PHZ_c0897 1.3e-42 179.9 Bacteria Bacteria COG4338@1,COG4338@2 NA|NA|NA U Protein conserved in bacteria MAG.T12.39_00079 450851.PHZ_c0104 2.7e-154 551.6 Caulobacterales leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MUH4@1224,2KEY4@204458,2TQKG@28211,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate MAG.T12.39_00080 450851.PHZ_c0105 4.3e-88 330.9 Caulobacterales leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MVXB@1224,2KGIH@204458,2TRRS@28211,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate MAG.T12.39_00081 1280944.HY17_00100 3.9e-41 175.3 Hyphomonadaceae MA20_16915 Bacteria 1MXZ4@1224,2TUBZ@28211,43XQV@69657,COG0346@1,COG0346@2 NA|NA|NA E COG0346 Lactoylglutathione lyase and related lyases MAG.T12.39_00082 450851.PHZ_c0107 2e-229 801.6 Caulobacterales leuC 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MVYR@1224,2KF2D@204458,2TR6K@28211,COG0065@1,COG0065@2 NA|NA|NA H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate MAG.T12.39_00083 426117.M446_6571 2.7e-167 595.1 Methylobacteriaceae wbpA 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 Bacteria 1JS0E@119045,1MUC6@1224,2TR5F@28211,COG0677@1,COG0677@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T12.39_00084 450851.PHZ_c3459 5.7e-51 207.2 Caulobacterales Bacteria 1R9XB@1224,2KGRF@204458,2U59E@28211,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family MAG.T12.39_00085 1449049.JONW01000006_gene2649 1.1e-157 562.8 Caulobacterales trpS 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV4T@1224,2KG0W@204458,2TQZX@28211,COG0180@1,COG0180@2 NA|NA|NA J Tryptophanyl-tRNA synthetase MAG.T12.39_00086 450851.PHZ_c3461 3.5e-185 654.8 Caulobacterales murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 iECO103_1326.ECO103_1114 Bacteria 1MUH0@1224,2KFYT@204458,2TS44@28211,COG0728@1,COG0728@2 NA|NA|NA S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane MAG.T12.39_00087 450851.PHZ_c3463 0.0 1376.3 Caulobacterales glnD GO:0003674,GO:0003824,GO:0006082,GO:0006355,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0045893,GO:0045935,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070569,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Bacteria 1MV54@1224,2KF01@204458,2TSV0@28211,COG2844@1,COG2844@2 NA|NA|NA O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen MAG.T12.39_00088 1035191.HMPREF0185_02919 3e-88 332.0 Caulobacterales natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1QUPV@1224,2KFE7@204458,2TWB4@28211,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter MAG.T12.39_00089 1382303.JPOM01000001_gene2304 2e-58 233.4 Caulobacterales natB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1R62N@1224,2KGCU@204458,2U1RZ@28211,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein MAG.T12.39_00090 1123240.ATVO01000009_gene742 1.3e-33 149.4 Alphaproteobacteria Bacteria 1R3EC@1224,2DWCQ@1,2U01J@28211,33ZNG@2 NA|NA|NA MAG.T12.39_00091 1282876.BAOK01000002_gene484 5.3e-103 380.9 unclassified Alphaproteobacteria Bacteria 1MXBX@1224,2U4PZ@28211,4BTDM@82117,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T12.39_00092 1040982.AXAL01000024_gene6356 9.1e-43 180.3 Phyllobacteriaceae Bacteria 1RGIB@1224,2E21J@1,2UC7C@28211,32X9B@2,43K21@69277 NA|NA|NA S Domain of unknown function (DUF4893) MAG.T12.39_00093 509190.Cseg_1892 3.2e-65 255.0 Caulobacterales ompW ko:K07275 ko00000 Bacteria 1NUZJ@1224,2KGAT@204458,2TRGI@28211,COG3047@1,COG3047@2 NA|NA|NA M PFAM OmpW family protein MAG.T12.39_00095 190650.CC_3681 9.2e-38 163.3 Caulobacterales terB ko:K05793,ko:K05795 ko00000 Bacteria 1RD4Q@1224,2KIWV@204458,2UFQW@28211,COG3793@1,COG3793@2 NA|NA|NA P Tellurite resistance protein TerB MAG.T12.39_00096 883078.HMPREF9695_01831 3.2e-67 261.9 Bradyrhizobiaceae MA20_16335 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 iAF987.Gmet_2224 Bacteria 1MWF6@1224,2TVBC@28211,3JSPF@41294,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_00097 402881.Plav_0366 3e-164 585.1 Alphaproteobacteria Bacteria 1MUQH@1224,2TRG4@28211,COG2072@1,COG2072@2 NA|NA|NA P Flavoprotein involved in K transport MAG.T12.39_00098 1122604.JONR01000011_gene3676 1.2e-98 366.7 Xanthomonadales Bacteria 1MVPR@1224,1S5WE@1236,1X3ZI@135614,COG1680@1,COG1680@2 NA|NA|NA V beta-lactamase MAG.T12.39_00099 661478.OP10G_1192 3.1e-73 282.0 Bacteria Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase MAG.T12.39_00100 1112214.AHIS01000012_gene44 4e-109 401.4 Sphingomonadales bah Bacteria 1R4BT@1224,2KCRA@204457,2U1ZH@28211,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T12.39_00101 715226.ABI_21040 3.8e-81 307.8 Caulobacterales wrbA 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1MW7N@1224,2KG63@204458,2TR4Z@28211,COG0655@1,COG0655@2 NA|NA|NA C Belongs to the WrbA family MAG.T12.39_00102 1123242.JH636434_gene5367 4.4e-97 362.1 Planctomycetes ko:K01138 ko00000,ko01000 Bacteria 2IYH5@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A MAG.T12.39_00103 450851.PHZ_c1331 1.2e-283 982.2 Caulobacterales ppcE 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 1NZ7N@1224,2KFFQ@204458,2TTAX@28211,COG1505@1,COG1505@2 NA|NA|NA E peptidase S9A prolyl oligopeptidase domain protein beta-propeller MAG.T12.39_00104 1502852.FG94_03951 2e-182 646.4 Betaproteobacteria yhcD Bacteria 1R6ZJ@1224,2VPW6@28216,COG3188@1,COG3188@2 NA|NA|NA NU usher protein MAG.T12.39_00105 270374.MELB17_03430 1.9e-68 266.2 Alteromonadaceae 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1RFSJ@1224,1S3QQ@1236,4681N@72275,COG3121@1,COG3121@2 NA|NA|NA NU COG3121 P pilus assembly protein, chaperone PapD MAG.T12.39_00109 215803.DB30_1533 8.7e-53 213.8 Myxococcales nudF1 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1QTT4@1224,2WPWK@28221,2YY1W@29,42SX4@68525,COG1051@1,COG1051@2 NA|NA|NA F Belongs to the Nudix hydrolase family MAG.T12.39_00110 572477.Alvin_2299 2.4e-108 399.4 Chromatiales Bacteria 1PMP6@1224,1TK5S@1236,1WZKE@135613,COG1397@1,COG1397@2,COG2453@1,COG2453@2 NA|NA|NA O ADP-ribosylglycohydrolase MAG.T12.39_00111 1230476.C207_00462 6.6e-97 360.5 Bradyrhizobiaceae Bacteria 1MU32@1224,2TUYY@28211,3JUT8@41294,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_00112 264198.Reut_B4295 4.5e-27 128.6 Betaproteobacteria ko:K06889 ko00000 Bacteria 1RIWI@1224,2VJF9@28216,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily MAG.T12.39_00113 1121033.AUCF01000030_gene172 9.2e-12 78.6 Bacteria Bacteria COG0457@1,COG0457@2,COG3914@1,COG3914@2 NA|NA|NA O protein N-acetylglucosaminyltransferase activity MAG.T12.39_00114 1449049.JONW01000011_gene2349 6.1e-99 367.9 Alphaproteobacteria vioA GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771 2.6.1.33 ko:K13308,ko:K20429 ko00523,ko01130,map00523,map01130 M00797 R02773 RC00006,RC00781 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPN@1224,2U51A@28211,COG0399@1,COG0399@2 NA|NA|NA M Belongs to the DegT DnrJ EryC1 family MAG.T12.39_00115 1082932.ATCR1_11138 1.2e-80 307.8 Rhizobiaceae suhR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1N9HS@1224,2U193@28211,4BE9V@82115,COG1752@1,COG1752@2 NA|NA|NA S Patatin-like phospholipase MAG.T12.39_00116 391600.ABRU01000025_gene1187 4.4e-64 251.1 Alphaproteobacteria Bacteria 1QXKQ@1224,2TXBW@28211,COG2230@1,COG2230@2 NA|NA|NA M COG0500 SAM-dependent methyltransferases MAG.T12.39_00117 547163.BN979_04234 1.4e-25 123.6 Mycobacteriaceae Bacteria 237M9@1762,2I7KM@201174,COG1946@1,COG1946@2 NA|NA|NA I Thioesterase-like superfamily MAG.T12.39_00118 450851.PHZ_c1018 1.2e-234 818.9 Caulobacterales calB 1.2.1.68 ko:K00154 ko00000,ko01000 Bacteria 1MVGW@1224,2KEXQ@204458,2TR9T@28211,COG1012@1,COG1012@2 NA|NA|NA C belongs to the aldehyde dehydrogenase family MAG.T12.39_00119 670292.JH26_01285 5.3e-11 73.2 Alphaproteobacteria Bacteria 1P8S1@1224,298XH@1,2UXWE@28211,2ZW1C@2 NA|NA|NA MAG.T12.39_00121 1430440.MGMSRv2_3766 2e-140 505.8 Alphaproteobacteria Bacteria 1R4EM@1224,28KXQ@1,2UPQE@28211,2ZADJ@2 NA|NA|NA S Evidence 4 Homologs of previously reported genes of MAG.T12.39_00122 158500.BV97_05657 6.6e-94 352.1 Sphingomonadales Bacteria 1PQ1U@1224,2KBXP@204457,2V2GY@28211,COG0323@1,COG0323@2 NA|NA|NA L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T12.39_00123 582899.Hden_0657 2.1e-18 99.0 Alphaproteobacteria Bacteria 1NQ39@1224,2CKCW@1,2UJNC@28211,2ZCTT@2 NA|NA|NA MAG.T12.39_00125 225937.HP15_650 4e-29 134.4 Gammaproteobacteria gpU ko:K06906 ko00000 Bacteria 1MZJ7@1224,1S3NI@1236,COG3499@1,COG3499@2 NA|NA|NA S P2 GpU family protein MAG.T12.39_00126 1211112.ALJC01000089_gene755 2.8e-44 185.7 Gammaproteobacteria Bacteria 1N8BU@1224,1SGVN@1236,2EAFZ@1,334JC@2 NA|NA|NA S Domain of unknown function (DUF4393) MAG.T12.39_00129 1205680.CAKO01000002_gene2870 9.8e-119 433.3 Rhodospirillales 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MWRK@1224,2JWAK@204441,2TSPW@28211,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T12.39_00130 652103.Rpdx1_2744 2.5e-88 332.0 Bradyrhizobiaceae Bacteria 1MXVZ@1224,2TVJW@28211,3JXVQ@41294,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T12.39_00131 450851.PHZ_c0461 1.1e-174 619.8 Caulobacterales pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iHN637.CLJU_RS08925 Bacteria 1MV3H@1224,2KJGW@204458,2TS24@28211,COG0213@1,COG0213@2 NA|NA|NA F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis MAG.T12.39_00132 450851.PHZ_c0462 3.4e-65 255.4 Alphaproteobacteria 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUV7@1224,2U5MQ@28211,COG0462@1,COG0462@2 NA|NA|NA F Belongs to the ribose-phosphate pyrophosphokinase family MAG.T12.39_00133 1280950.HJO_11277 2.4e-128 465.3 Hyphomonadaceae Bacteria 1MXUX@1224,2TTWF@28211,43YZF@69657,COG0604@1,COG0604@2 NA|NA|NA C NADPH quinone MAG.T12.39_00134 1280941.HY2_04335 4.2e-69 267.7 Hyphomonadaceae IV02_13550 Bacteria 1RDDV@1224,2U7JH@28211,43ZTU@69657,COG2119@1,COG2119@2 NA|NA|NA S membrane MAG.T12.39_00135 1267533.KB906733_gene2904 2e-78 299.3 Acidobacteriia salL GO:0003674,GO:0003824,GO:0016740,GO:0016765 2.5.1.63,2.5.1.94 ko:K09134,ko:K21153,ko:K22205 ko00000,ko01000 Bacteria 2JM3U@204432,3Y6D9@57723,COG1912@1,COG1912@2 NA|NA|NA S S-adenosyl-l-methionine hydroxide adenosyltransferase MAG.T12.39_00136 551789.ATVJ01000001_gene2003 1.3e-107 396.7 Hyphomonadaceae Bacteria 1MVPR@1224,2TRWZ@28211,43WQS@69657,COG1680@1,COG1680@2 NA|NA|NA V COG1680 Beta-lactamase class C and other penicillin binding proteins MAG.T12.39_00137 1192759.AKIB01000014_gene1651 1.8e-37 163.3 Sphingomonadales Bacteria 1N2XW@1224,2K1P0@204457,2U0CF@28211,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T12.39_00138 1038859.AXAU01000025_gene4127 2.6e-199 701.4 Bradyrhizobiaceae MA20_16395 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU2V@1224,2TSK3@28211,3JR07@41294,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain MAG.T12.39_00139 450851.PHZ_c3396 1.6e-82 312.4 Caulobacterales MA20_30275 ko:K12410 ko00000,ko01000 Bacteria 1MUK1@1224,2KGA0@204458,2TV1Q@28211,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form MAG.T12.39_00140 488538.SAR116_0035 1.8e-128 466.1 unclassified Alphaproteobacteria amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1NR9F@1224,2TT2J@28211,4BP5Z@82117,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family MAG.T12.39_00141 450851.PHZ_c1081 1.3e-127 462.6 Caulobacterales purU 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1MVCF@1224,2KFGR@204458,2TR4V@28211,COG0788@1,COG0788@2 NA|NA|NA F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) MAG.T12.39_00142 748727.CLJU_c24630 1.6e-31 142.5 Clostridiaceae 3.6.1.13,3.6.1.67 ko:K01515,ko:K08310 ko00230,ko00790,map00230,map00790 M00126 R01054,R04638 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1VFWX@1239,24NIQ@186801,36KKB@31979,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T12.39_00143 450851.PHZ_c3393 3e-23 114.4 Caulobacterales yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1N73Q@1224,2KH9E@204458,2UFZR@28211,COG0762@1,COG0762@2 NA|NA|NA S YGGT family MAG.T12.39_00145 311403.Arad_4259 2.7e-32 145.2 Rhizobiaceae adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1RCIS@1224,2UN30@28211,4BIWH@82115,COG0563@1,COG0563@2 NA|NA|NA F COG0563 Adenylate kinase and related kinases MAG.T12.39_00147 393921.HQ45_03770 2.6e-13 81.6 Porphyromonadaceae Bacteria 230UN@171551,2FVGZ@200643,4NTTC@976,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain MAG.T12.39_00149 13690.CP98_02673 3.5e-52 211.8 Sphingomonadales Bacteria 1RAC3@1224,2K1CU@204457,2U59H@28211,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T12.39_00150 1121022.ABENE_21490 1.2e-169 603.2 Caulobacterales Bacteria 1MU3F@1224,2KFW2@204458,2TT3C@28211,COG2303@1,COG2303@2 NA|NA|NA E Oxidoreductase MAG.T12.39_00151 369723.Strop_2533 3e-62 245.4 Micromonosporales gip 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 2GKPC@201174,4DKEP@85008,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T12.39_00152 1185766.DL1_15655 1.4e-124 453.0 Thioclava Bacteria 1MVVF@1224,2TR6B@28211,2XPA7@285107,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T12.39_00153 1122929.KB908222_gene2366 2.8e-156 558.1 Alphaproteobacteria Bacteria 1MVSJ@1224,2TV5J@28211,COG1082@1,COG1082@2 NA|NA|NA G AP endonuclease MAG.T12.39_00154 414684.RC1_2776 2e-59 235.7 Rhodospirillales kynB GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1P8U5@1224,2JS2X@204441,2U7KU@28211,COG1878@1,COG1878@2 NA|NA|NA S Putative cyclase MAG.T12.39_00155 383381.EH30_12260 1.8e-106 392.9 Sphingomonadales kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUKN@1224,2K1KR@204457,2TR62@28211,COG3844@1,COG3844@2 NA|NA|NA E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively MAG.T12.39_00156 450851.PHZ_c2314 8.3e-178 630.2 Caulobacterales Bacteria 1R4SE@1224,2KG1A@204458,2U0Q5@28211,COG1387@1,COG1387@2 NA|NA|NA E PHP domain protein MAG.T12.39_00157 1120951.AUBG01000013_gene2701 3.2e-149 535.4 Flavobacteriia Bacteria 1HZ70@117743,4NFMV@976,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T12.39_00158 450851.PHZ_c3388 0.0 1359.7 Caulobacterales polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1MU31@1224,2KF96@204458,2TRJF@28211,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity MAG.T12.39_00159 1292034.OR37_00741 3.9e-21 107.1 Caulobacterales MA20_32275 Bacteria 1N7F4@1224,2KH74@204458,2UFVF@28211,COG4391@1,COG4391@2 NA|NA|NA S Zinc-finger domain MAG.T12.39_00160 450851.PHZ_c3466 4e-141 507.7 Caulobacterales yadG ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 Bacteria 1MUW7@1224,2KFJM@204458,2TR2Q@28211,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T12.39_00161 375286.mma_1189 1.9e-24 119.0 Oxalobacteraceae Bacteria 1NFBV@1224,2E3QW@1,2VWPZ@28216,32YNQ@2,477JM@75682 NA|NA|NA S Periplasmic lysozyme inhibitor of I-type lysozyme MAG.T12.39_00162 1122614.JHZF01000014_gene2718 2.6e-109 401.7 Proteobacteria 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 Bacteria 1MVQN@1224,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase MAG.T12.39_00163 1121949.AQXT01000002_gene191 1.2e-106 393.3 Hyphomonadaceae Bacteria 1R7XK@1224,2TTWB@28211,43XYD@69657,COG3173@1,COG3173@2 NA|NA|NA S Aminoglycoside phosphotransferase MAG.T12.39_00164 1280952.HJA_10820 2.5e-43 181.4 Alphaproteobacteria Bacteria 1NHKV@1224,2UTI1@28211,COG4319@1,COG4319@2 NA|NA|NA S SnoaL-like domain MAG.T12.39_00165 1280944.HY17_04340 3.4e-156 558.1 Hyphomonadaceae pltD 1.14.19.49 ko:K14257 ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130 M00790,M00823 R05456,R11106,R11478 RC00949 ko00000,ko00001,ko00002,ko01000 Bacteria 1R7NX@1224,2UN05@28211,43Z1V@69657,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T12.39_00166 1411123.JQNH01000001_gene640 1.6e-39 169.1 Alphaproteobacteria aroQ 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 iIT341.HP1038 Bacteria 1RDDT@1224,2U9BV@28211,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate MAG.T12.39_00167 1282360.ABAC460_00805 1.5e-22 113.2 Bacteria Bacteria COG3548@1,COG3548@2 NA|NA|NA S protein homotetramerization MAG.T12.39_00168 1245471.PCA10_24270 1e-32 146.4 Pseudomonas aeruginosa group yhbS GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 ko:K03824 ko00000,ko01000 Bacteria 1RA42@1224,1S2G0@1236,1YGNX@136841,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) domain MAG.T12.39_00170 69395.JQLZ01000009_gene1803 1e-135 490.3 Caulobacterales hemY ko:K02498 ko00000 Bacteria 1P5RR@1224,2KFSN@204458,2TT5Q@28211,COG3898@1,COG3898@2 NA|NA|NA S PFAM HemY domain protein MAG.T12.39_00171 1449049.JONW01000006_gene2774 2e-30 139.8 Caulobacterales 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 1Q3YR@1224,2KH47@204458,2VAHG@28211,COG4223@1,COG4223@2 NA|NA|NA DZ transferase activity, transferring acyl groups other than amino-acyl groups MAG.T12.39_00172 69395.JQLZ01000009_gene1805 1.2e-33 150.2 Caulobacterales hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K02496,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0187,iSBO_1134.SBO_3815 Bacteria 1NMTP@1224,2KH06@204458,2U1Y2@28211,COG1587@1,COG1587@2 NA|NA|NA H PFAM Uroporphyrinogen III synthase HEM4 MAG.T12.39_00173 509190.Cseg_0063 5.2e-103 380.9 Caulobacterales hemC 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU56@1224,2KF8V@204458,2TS3D@28211,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps MAG.T12.39_00174 1449049.JONW01000006_gene2771 2.5e-139 501.9 Caulobacterales tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1MU6S@1224,2KFVE@204458,2TSF7@28211,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction MAG.T12.39_00175 69395.JQLZ01000009_gene1808 8.2e-129 466.8 Caulobacterales gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1MUU3@1224,2KFVM@204458,2TT75@28211,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase MAG.T12.39_00176 450851.PHZ_c3408 1.7e-23 115.2 Caulobacterales ko:K09780 ko00000 Bacteria 1MZ9Z@1224,2KHD9@204458,2UF4X@28211,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain MAG.T12.39_00177 450851.PHZ_c3409 8.1e-42 176.4 Caulobacterales 2.7.1.3 ko:K00846,ko:K05710 ko00051,ko00360,ko01100,ko01120,ko01220,map00051,map00360,map01100,map01120,map01220 M00545 R00866,R03819,R06782,R06783 RC00002,RC00017,RC00098,RC00608 br01602,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1N72F@1224,2KJUD@204458,2UFDN@28211,COG2146@1,COG2146@2 NA|NA|NA P PFAM Rieske 2Fe-2S iron-sulphur domain MAG.T12.39_00178 1219035.NT2_06_02100 1.2e-116 426.0 Sphingomonadales 3.5.2.10 ko:K01470 ko00330,map00330 R01884 RC00615 ko00000,ko00001,ko01000 Bacteria 1MXR9@1224,2KB4V@204457,2TUFR@28211,COG1402@1,COG1402@2 NA|NA|NA S Creatinine amidohydrolase MAG.T12.39_00179 450851.PHZ_c3413 0.0 1115.5 Caulobacterales acsA 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MUF5@1224,2KG2R@204458,2TRKS@28211,COG0365@1,COG0365@2 NA|NA|NA H Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA MAG.T12.39_00180 622637.KE124774_gene1516 3.7e-73 282.0 Methylocystaceae Bacteria 1MWMM@1224,2TQX8@28211,36Y95@31993,COG5459@1,COG5459@2 NA|NA|NA J Mitochondrial small ribosomal subunit Rsm22 MAG.T12.39_00182 450851.PHZ_c3505 2.3e-291 1008.1 Caulobacterales ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1MVPI@1224,2KFXJ@204458,2TR48@28211,COG1674@1,COG1674@2 NA|NA|NA D cell division protein FtsK MAG.T12.39_00183 450851.PHZ_c3507 7.4e-59 233.8 Caulobacterales lolA Bacteria 1RA1S@1224,2KGFT@204458,2U58W@28211,COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) MAG.T12.39_00184 59538.XP_005978946.1 6.6e-113 413.7 Eukaryota 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Eukaryota COG0708@1,KOG1294@2759 NA|NA|NA L double-stranded DNA 3'-5' exodeoxyribonuclease activity MAG.T12.39_00185 450851.PHZ_c3509 2.4e-87 328.6 Caulobacterales Bacteria 1MU3A@1224,2KFEM@204458,2TR97@28211,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00186 1382303.JPOM01000001_gene997 2.1e-56 225.3 Caulobacterales ddpX 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1RH22@1224,2KGWD@204458,2U992@28211,COG3786@1,COG3786@2 NA|NA|NA S L,D-transpeptidase catalytic domain MAG.T12.39_00187 450851.PHZ_c3513 1.3e-82 312.8 Caulobacterales yggS ko:K06997 ko00000 Bacteria 1MWN7@1224,2KFJ9@204458,2TR5Z@28211,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MAG.T12.39_00188 190650.CC_3747 9.8e-20 103.2 Caulobacterales Bacteria 1N8R5@1224,2E3XQ@1,2KHDG@204458,2UHB5@28211,32YUR@2 NA|NA|NA MAG.T12.39_00189 190650.CC_3748 1.1e-49 203.0 Caulobacterales Bacteria 1RHAH@1224,2C2J5@1,2KGNX@204458,2U94W@28211,315UG@2 NA|NA|NA S Domain of unknown function (DUF3576) MAG.T12.39_00190 450851.PHZ_c3517 0.0 1344.7 Caulobacterales leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 Bacteria 1MV47@1224,2KFX5@204458,2TQPK@28211,COG0495@1,COG0495@2 NA|NA|NA J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm MAG.T12.39_00191 450851.PHZ_c3518 5.5e-41 174.1 Caulobacterales ko:K03643 ko00000,ko02000 1.B.42.1 Bacteria 1N14E@1224,2KGXB@204458,2UDSE@28211,COG5468@1,COG5468@2 NA|NA|NA S Lipopolysaccharide-assembly MAG.T12.39_00192 450851.PHZ_c3519 1.7e-129 469.2 Caulobacterales holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1R8PA@1224,2KFTW@204458,2U1KQ@28211,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III MAG.T12.39_00193 1248916.ANFY01000005_gene2644 3.8e-91 341.3 Sphingomonadales Bacteria 1R439@1224,2K92J@204457,2U0N2@28211,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T12.39_00194 1382303.JPOM01000001_gene76 8.8e-79 300.4 Caulobacterales parB ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1MW2E@1224,2KFXZ@204458,2TSTN@28211,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family MAG.T12.39_00195 450851.PHZ_c3521 8.1e-119 433.3 Caulobacterales parA ko:K03496,ko:K12055 ko00000,ko02044,ko03036,ko04812 3.A.7.11.1 Bacteria 1MV43@1224,2KFAA@204458,2TSWH@28211,COG1192@1,COG1192@2 NA|NA|NA D Chromosome partitioning protein ParA MAG.T12.39_00196 450851.PHZ_c3522 1.4e-71 276.2 Caulobacterales rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1MY0K@1224,2KGDV@204458,2U9T9@28211,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA MAG.T12.39_00197 450851.PHZ_c3526 1.2e-287 995.3 Caulobacterales gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1MU6F@1224,2KF86@204458,2TRJS@28211,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 MAG.T12.39_00198 450851.PHZ_c3527 7.3e-141 507.3 Caulobacterales mnmE ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1MUCQ@1224,2KFRG@204458,2TQZW@28211,COG0486@1,COG0486@2 NA|NA|NA J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 MAG.T12.39_00199 69395.JQLZ01000009_gene1963 6.5e-27 126.3 Caulobacterales ko:K15539 ko00000 Bacteria 1NC0S@1224,2KHA3@204458,2UG0A@28211,COG3266@1,COG3266@2 NA|NA|NA S domain, Protein MAG.T12.39_00200 1449049.JONW01000006_gene2582 1.2e-81 309.7 Caulobacterales clcD 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1MW88@1224,2KG13@204458,2U1D8@28211,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T12.39_00201 450851.PHZ_c3530 8.8e-112 410.2 Caulobacterales qor 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MWBD@1224,2KF2V@204458,2TS3Z@28211,COG0604@1,COG0604@2 NA|NA|NA C PFAM Alcohol dehydrogenase zinc-binding domain protein MAG.T12.39_00202 450851.PHZ_c3531 6.8e-225 786.6 Caulobacterales rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 1MUCF@1224,2KFVG@204458,2TRB4@28211,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T12.39_00203 1382303.JPOM01000001_gene67 6.3e-52 210.3 Caulobacterales MA20_24805 ko:K08973 ko00000 Bacteria 1RHGS@1224,2KGYK@204458,2U987@28211,COG1981@1,COG1981@2 NA|NA|NA S Uncharacterised protein family (UPF0093) MAG.T12.39_00204 450851.PHZ_c3533 1.9e-144 518.8 Caulobacterales hemH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVR1@1224,2KEZC@204458,2TSMS@28211,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX MAG.T12.39_00205 450851.PHZ_c3534 2.1e-141 508.8 Caulobacterales hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUG1@1224,2KFZ4@204458,2TQQV@28211,COG0407@1,COG0407@2 NA|NA|NA H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III MAG.T12.39_00206 450851.PHZ_c0001 5.1e-124 450.7 Caulobacterales yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1MUHU@1224,2KFUV@204458,2TT66@28211,COG1806@1,COG1806@2 NA|NA|NA S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation MAG.T12.39_00207 450851.PHZ_c0002 6.8e-51 207.2 Caulobacterales maf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030312,GO:0044464,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1RDA9@1224,2KGRS@204458,2U9H5@28211,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T12.39_00208 69395.JQLZ01000009_gene1954 5.6e-78 297.7 Caulobacterales aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVH4@1224,2KGD9@204458,2TS99@28211,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) MAG.T12.39_00209 450851.PHZ_c0004 2.7e-69 268.5 Caulobacterales coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,3.2.2.23,4.2.99.18,5.4.99.23 ko:K00859,ko:K06180,ko:K10563 ko00770,ko01100,ko03410,map00770,map01100,map03410 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko03009,ko03400 Bacteria 1RCXT@1224,2KGDA@204458,2U765@28211,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A MAG.T12.39_00210 450851.PHZ_c0005 5.4e-87 327.4 Caulobacterales dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MV8Z@1224,2KG17@204458,2TTFF@28211,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease MAG.T12.39_00211 450851.PHZ_c0006 4.7e-61 240.7 Caulobacterales secB GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 Bacteria 1RI75@1224,2KGQP@204458,2UBTB@28211,COG1952@1,COG1952@2 NA|NA|NA U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA MAG.T12.39_00212 509190.Cseg_4247 3.6e-42 178.3 Caulobacterales MA20_24770 ko:K15539 ko00000 Bacteria 1NCIX@1224,2KGES@204458,2TTDQ@28211,COG4395@1,COG4395@2 NA|NA|NA S PFAM import inner membrane translocase subunit Tim44 MAG.T12.39_00213 1292034.OR37_01745 1.1e-88 333.2 Caulobacterales mltA GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K08304 ko00000,ko01000,ko01011 GH102 iECABU_c1320.ECABU_c30840 Bacteria 1MXD4@1224,2KGQH@204458,2TS5S@28211,COG2821@1,COG2821@2 NA|NA|NA M MltA specific insert domain MAG.T12.39_00214 450851.PHZ_c0009 1.6e-46 192.6 Caulobacterales yfcN GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 Bacteria 1RH34@1224,2KH0U@204458,2UCM1@28211,COG2840@1,COG2840@2 NA|NA|NA S PFAM Smr protein MutS2 MAG.T12.39_00215 1192759.AKIB01000004_gene470 1.5e-84 320.1 Sphingomonadales Bacteria 1MVID@1224,2K09V@204457,2TUR0@28211,COG1301@1,COG1301@2 NA|NA|NA C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family MAG.T12.39_00216 349102.Rsph17025_2253 6.3e-25 120.2 Rhodobacter hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria 1FBXX@1060,1MZEE@1224,2UBU3@28211,COG0140@1,COG0140@2 NA|NA|NA F PFAM phosphoribosyl-ATP pyrophosphohydrolase MAG.T12.39_00217 450851.PHZ_c0043 9.2e-104 383.3 Caulobacterales hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUS0@1224,2KG32@204458,2TQXD@28211,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit MAG.T12.39_00218 450851.PHZ_c0042 6.3e-107 393.7 Caulobacterales hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1MW6S@1224,2KGSM@204458,2TRSG@28211,COG0106@1,COG0106@2 NA|NA|NA E Histidine biosynthesis protein MAG.T12.39_00219 450851.PHZ_c0041 7.5e-80 303.5 Caulobacterales hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4X@1224,2KGF8@204458,2TTT4@28211,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR MAG.T12.39_00220 190650.CC_3734 9.8e-82 309.7 Caulobacterales hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1MWBS@1224,2KG4T@204458,2TTVV@28211,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase MAG.T12.39_00221 450851.PHZ_c0039 6e-124 450.7 Caulobacterales frk 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MUUC@1224,2KG1B@204458,2TS9D@28211,COG0524@1,COG0524@2 NA|NA|NA G PFAM PfkB domain protein MAG.T12.39_00222 450851.PHZ_c0797 3.8e-68 265.0 Caulobacterales 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1QCY4@1224,2KIK8@204458,2UR9G@28211,COG0652@1,COG0652@2 NA|NA|NA O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MAG.T12.39_00223 450851.PHZ_c0038 1.2e-88 332.8 Caulobacterales nth GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUYQ@1224,2KFH8@204458,2TRI2@28211,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T12.39_00224 1280950.HJO_08517 9.5e-73 280.8 Hyphomonadaceae GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 ko:K21785 ko00333,ko01130,map00333,map01130 M00837,M00838 R11668,R11669 ko00000,ko00001,ko00002 Bacteria 1NTK9@1224,2TR3E@28211,43Z5Y@69657,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase MAG.T12.39_00225 1282876.BAOK01000001_gene2803 1.3e-22 112.8 Alphaproteobacteria ywoH ko:K06075 ko00000,ko03000 Bacteria 1RD9U@1224,2U7NF@28211,COG1846@1,COG1846@2 NA|NA|NA K transcriptional regulator MAG.T12.39_00226 1280950.HJO_08522 4.8e-28 131.0 Alphaproteobacteria ywoH ko:K06075 ko00000,ko03000 Bacteria 1RD9U@1224,2U7NF@28211,COG1846@1,COG1846@2 NA|NA|NA K transcriptional regulator MAG.T12.39_00227 450851.PHZ_c0037 1.6e-29 136.0 Caulobacterales Bacteria 1MZF1@1224,2KH4N@204458,2UE6Q@28211,COG5488@1,COG5488@2 NA|NA|NA S Integral membrane protein (DUF2244) MAG.T12.39_00228 509190.Cseg_4263 3.8e-97 361.3 Caulobacterales moeB 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 1MW7H@1224,2KF6H@204458,2TRWY@28211,COG0476@1,COG0476@2 NA|NA|NA H PFAM UBA THIF-type NAD FAD binding protein MAG.T12.39_00229 190650.CC_0745 2.9e-213 748.0 Caulobacterales ydaH ko:K12942 ko00000 Bacteria 1MUJ1@1224,2KFNM@204458,2U1AP@28211,COG2978@1,COG2978@2 NA|NA|NA H PFAM AbgT MAG.T12.39_00230 450851.PHZ_c0031 4.5e-156 557.4 Caulobacterales gyaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 Bacteria 1MU2D@1224,2KF6Y@204458,2TSM8@28211,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family MAG.T12.39_00231 450851.PHZ_c0030 8.5e-51 206.8 Caulobacterales MA20_24010 3.2.1.96,3.4.17.14,3.5.1.28,6.1.1.12 ko:K01227,ko:K01447,ko:K01448,ko:K01876,ko:K06385,ko:K07260,ko:K11060,ko:K11062 ko00511,ko00550,ko00970,ko01100,ko01502,ko01503,ko02020,map00511,map00550,map00970,map01100,map01502,map01503,map02020 M00359,M00360,M00651,M00727 R04112,R05577 RC00055,RC00064,RC00141,RC00523 ko00000,ko00001,ko00002,ko01000,ko01002,ko01007,ko01011,ko01504,ko02042,ko03016,ko03029,ko03036 Bacteria 1RHM2@1224,2KGPB@204458,2UA1R@28211,COG3807@1,COG3807@2 NA|NA|NA S Bacterial SH3 domain MAG.T12.39_00232 1292034.OR37_01411 2.9e-77 294.7 Caulobacterales fabA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090 Bacteria 1MWV8@1224,2KF8H@204458,2TV8S@28211,COG0764@1,COG0764@2 NA|NA|NA I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length MAG.T12.39_00233 450851.PHZ_c0028 1.8e-191 675.2 Caulobacterales fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Bacteria 1MU1X@1224,2KF15@204458,2TQYV@28211,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family MAG.T12.39_00234 450851.PHZ_c0026 8.4e-116 423.3 Caulobacterales fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MV05@1224,2KFRP@204458,2TSU4@28211,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH MAG.T12.39_00235 69395.JQLZ01000010_gene4134 3.4e-47 195.3 Caulobacterales ko:K18301 M00642 ko00000,ko00002,ko01504,ko03000 Bacteria 1QA1G@1224,2KGQ6@204458,2UAZT@28211,COG1309@1,COG1309@2 NA|NA|NA K PFAM regulatory protein TetR MAG.T12.39_00236 450851.PHZ_c0022 1.1e-167 596.3 Caulobacterales ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU6I@1224,2KF3N@204458,2TRZU@28211,COG0654@1,COG0654@2 NA|NA|NA CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family MAG.T12.39_00237 450851.PHZ_c0021 3.8e-20 103.6 Caulobacterales ycaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 ko:K00912,ko:K09791 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1N6Y2@1224,2KHAU@204458,2UF4N@28211,COG2835@1,COG2835@2 NA|NA|NA S Belongs to the UPF0434 family MAG.T12.39_00238 366602.Caul_4589 1.1e-62 246.5 Caulobacterales lonD 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1NV9N@1224,2KGDQ@204458,2TQZ4@28211,COG2802@1,COG2802@2 NA|NA|NA S Peptidase S16, lon domain protein MAG.T12.39_00239 450851.PHZ_c0019 6.1e-107 394.0 Caulobacterales trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1MV0R@1224,2KF1N@204458,2TS5X@28211,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin MAG.T12.39_00240 450851.PHZ_c0018 2.4e-55 221.9 Caulobacterales proX ko:K19055 ko00000,ko01000,ko03016 Bacteria 1RDIG@1224,2KGNT@204458,2U87T@28211,COG3760@1,COG3760@2 NA|NA|NA S YbaK prolyl-tRNA synthetase associated MAG.T12.39_00241 450851.PHZ_c0017 5.7e-119 433.7 Caulobacterales Bacteria 1NCXC@1224,28PQS@1,2KG15@204458,2U2KV@28211,2ZCCP@2 NA|NA|NA MAG.T12.39_00244 1121385.AQXW01000004_gene3329 9.1e-96 357.8 Actinobacteria Bacteria 2H3T3@201174,COG2015@1,COG2015@2 NA|NA|NA Q Alkyl sulfatase dimerisation MAG.T12.39_00246 582899.Hden_2122 1.4e-57 229.6 Alphaproteobacteria Bacteria 1RAAZ@1224,2U5A9@28211,COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase MAG.T12.39_00247 59538.XP_005965339.1 1.2e-144 519.6 Cetartiodactyla Mammalia 38D2K@33154,3BE3X@33208,3CZIP@33213,3JBET@40674,486KW@7711,496BV@7742,4IY0T@91561,COG3268@1,KOG2733@2759 NA|NA|NA S saccharopine dehydrogenase-like oxidoreductase MAG.T12.39_00248 1292034.OR37_04045 2e-47 195.7 Caulobacterales Bacteria 1RGGT@1224,2A23N@1,2KK6N@204458,2U84G@28211,30QDW@2 NA|NA|NA MAG.T12.39_00249 190650.CC_0127 5.1e-42 177.2 Alphaproteobacteria GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0042221,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1NBHH@1224,2UA0K@28211,COG3788@1,COG3788@2 NA|NA|NA S Membrane-associated protein in eicosanoid and glutathione metabolism MAG.T12.39_00250 450851.PHZ_c3064 8.4e-178 629.8 Caulobacterales wbpE 2.6.1.98 ko:K13017 ko00520,map00520 R10141 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1MUPN@1224,2KF9Y@204458,2TRIQ@28211,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T12.39_00251 450851.PHZ_c3062 3.7e-224 784.3 Caulobacterales 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1MUIC@1224,2KF80@204458,2TRRZ@28211,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_00252 1121124.JNIX01000005_gene1311 4.1e-26 124.4 Caulobacterales Bacteria 1MZHP@1224,2KGX5@204458,2UBSF@28211,COG4852@1,COG4852@2 NA|NA|NA S Predicted membrane protein (DUF2177) MAG.T12.39_00253 450851.PHZ_c3058 6.3e-153 547.4 Caulobacterales ko:K06954 ko00000 Bacteria 1MV4Z@1224,2KG31@204458,2TQUH@28211,COG2907@1,COG2907@2 NA|NA|NA S Flavin containing amine oxidoreductase MAG.T12.39_00254 450851.PHZ_c3057 5.3e-83 314.3 Caulobacterales 2.1.1.79 ko:K00574,ko:K09701 ko00000,ko01000 Bacteria 1RC56@1224,2KGJK@204458,2TUX0@28211,COG3496@1,COG3496@2 NA|NA|NA S Protein of unknown function (DUF1365) MAG.T12.39_00255 1198452.Jab_2c09340 6.2e-17 94.0 Oxalobacteraceae Bacteria 1N6RE@1224,2W8FR@28216,477KD@75682,COG4704@1,COG4704@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2141) MAG.T12.39_00256 450851.PHZ_c3071 2.1e-55 222.2 Caulobacterales apl 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1MX4M@1224,2KJ0D@204458,2U6ZF@28211,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T12.39_00257 190650.CC_0644 4.3e-103 380.9 Caulobacterales Bacteria 1MWJQ@1224,2KHUP@204458,2TVRP@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T12.39_00258 450851.PHZ_c2217 5e-81 307.4 Caulobacterales MA20_25040 Bacteria 1RA6I@1224,2KI3Y@204458,2U5JB@28211,COG3917@1,COG3917@2 NA|NA|NA Q DSBA-like thioredoxin domain MAG.T12.39_00260 450851.PHZ_c3056 4.8e-74 284.3 Caulobacterales lemA ko:K03744 ko00000 Bacteria 1MVH0@1224,2KGCG@204458,2TRJR@28211,COG1704@1,COG1704@2 NA|NA|NA S LemA family MAG.T12.39_00261 509190.Cseg_0229 8.8e-62 243.8 Caulobacterales ko:K06872 ko00000 Bacteria 1PB41@1224,2KGEM@204458,2TUVD@28211,COG1512@1,COG1512@2 NA|NA|NA S TPM domain MAG.T12.39_00262 450851.PHZ_c3054 1.3e-61 243.0 Caulobacterales ko:K08988 ko00000 Bacteria 1R61N@1224,2KGU7@204458,2U5XG@28211,COG3762@1,COG3762@2 NA|NA|NA S membrane MAG.T12.39_00263 450851.PHZ_c3052 4.7e-63 247.3 Caulobacterales 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 1RD8C@1224,2KGN6@204458,2U6Z6@28211,COG2080@1,COG2080@2 NA|NA|NA C 2Fe-2S -binding domain protein MAG.T12.39_00264 450851.PHZ_c3051 6.3e-267 926.8 Caulobacterales 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 1QTTJ@1224,2KG0Z@204458,2TQVK@28211,COG1529@1,COG1529@2 NA|NA|NA C aldehyde oxidase and xanthine dehydrogenase molybdopterin binding MAG.T12.39_00265 450851.PHZ_c3048 1.1e-160 573.2 Alphaproteobacteria MA20_34745 ko:K07161 ko00000 Bacteria 1MUHH@1224,2U05M@28211,COG3552@1,COG3552@2 NA|NA|NA S Protein containing von Willebrand factor type A (VWA) domain MAG.T12.39_00266 450851.PHZ_c3047 2.2e-139 501.9 Caulobacterales MA20_34740 Bacteria 1MV5I@1224,2KFG3@204458,2TRI8@28211,COG0714@1,COG0714@2 NA|NA|NA S AAA domain (dynein-related subfamily) MAG.T12.39_00267 450851.PHZ_c3033 8.5e-148 530.0 Caulobacterales Bacteria 1MY4M@1224,2DB8I@1,2KFQG@204458,2U2A8@28211,2Z7RY@2 NA|NA|NA MAG.T12.39_00268 1382303.JPOM01000001_gene577 1.2e-167 596.3 Caulobacterales Bacteria 1MV8Q@1224,2KFJ6@204458,2TU15@28211,COG2124@1,COG2124@2 NA|NA|NA C cytochrome P450 MAG.T12.39_00269 450851.PHZ_c3034 3.6e-121 441.4 Caulobacterales Bacteria 1MWAK@1224,2KI9G@204458,2U36X@28211,COG3173@1,COG3173@2 NA|NA|NA S Phosphotransferase enzyme family MAG.T12.39_00270 402881.Plav_2502 8.3e-14 83.6 Alphaproteobacteria Bacteria 1NMCB@1224,2EGAZ@1,2UMCZ@28211,33A2U@2 NA|NA|NA MAG.T12.39_00271 1088721.NSU_2333 5e-53 213.8 Sphingomonadales MA20_16300 ko:K07068 ko00000 Bacteria 1R44D@1224,2K682@204457,2U5BU@28211,COG1545@1,COG1545@2 NA|NA|NA S Rubredoxin-like zinc ribbon domain (DUF35_N) MAG.T12.39_00272 1282876.BAOK01000001_gene984 8e-181 639.8 Alphaproteobacteria MA20_16305 Bacteria 1MUZV@1224,2TRHF@28211,COG0183@1,COG0183@2 NA|NA|NA I acetyl-coa acetyltransferase MAG.T12.39_00273 450851.PHZ_c3042 4.4e-113 415.2 Caulobacterales 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 1MXJ5@1224,2KF71@204458,2U1RY@28211,COG0613@1,COG0613@2 NA|NA|NA S PHP domain protein MAG.T12.39_00274 450851.PHZ_c0102 2.5e-52 211.8 Caulobacterales Bacteria 1NSPI@1224,2KK8X@204458,2TYPT@28211,COG0745@1,COG0745@2 NA|NA|NA T cheY-homologous receiver domain MAG.T12.39_00275 1292034.OR37_03043 1.6e-10 72.8 Caulobacterales Bacteria 1NMHF@1224,2EJN1@1,2KHFU@204458,2UMJ4@28211,33DCY@2 NA|NA|NA MAG.T12.39_00276 573065.Astex_3082 1.6e-194 685.3 Caulobacterales adhC 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MUK4@1224,2KFG5@204458,2TT67@28211,COG1062@1,COG1062@2 NA|NA|NA C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily MAG.T12.39_00277 1280941.HY2_08900 5.6e-119 434.1 Hyphomonadaceae fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MWPC@1224,2TQRT@28211,43XYZ@69657,COG2070@1,COG2070@2 NA|NA|NA S COG2070 Dioxygenases related to 2-nitropropane dioxygenase MAG.T12.39_00279 450851.PHZ_c1330 6.6e-123 447.2 Caulobacterales ko:K13572 ko00000,ko03051 Bacteria 1NQIT@1224,2KFYC@204458,2U42Q@28211,COG2378@1,COG2378@2 NA|NA|NA K WYL domain MAG.T12.39_00280 1122604.JONR01000001_gene2032 1e-288 999.2 Xanthomonadales Bacteria 1QTTJ@1224,1RNCM@1236,1X5W8@135614,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MAG.T12.39_00281 1500304.JQKY01000018_gene729 6.5e-55 220.3 Rhizobiaceae iorA5 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 1RD8C@1224,2U6Z6@28211,4BCPG@82115,COG2080@1,COG2080@2 NA|NA|NA C [2Fe-2S] binding domain MAG.T12.39_00282 402881.Plav_0832 1.7e-116 426.0 Rhodobiaceae Bacteria 1JQ4W@119043,1MY4Y@1224,2V94H@28211,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T12.39_00283 1150864.MILUP08_46282 5.7e-100 370.9 Micromonosporales Bacteria 2GMNA@201174,4D9RZ@85008,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase MAG.T12.39_00285 450851.PHZ_c1698 5.8e-303 1046.2 Caulobacterales MA20_01050 1.97.1.9 ko:K12527 ko00450,map00450 R07229 RC02420 ko00000,ko00001,ko01000 Bacteria 1MU2H@1224,2KJRT@204458,2TQK5@28211,COG0493@1,COG0493@2,COG1143@1,COG1143@2 NA|NA|NA C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster MAG.T12.39_00286 450851.PHZ_c1697 1e-281 975.7 Alphaproteobacteria korA 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1NBSJ@1224,2TU21@28211,COG0674@1,COG0674@2,COG1014@1,COG1014@2 NA|NA|NA C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit MAG.T12.39_00287 450851.PHZ_c1696 1.6e-167 595.5 Alphaproteobacteria MA20_01040 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1R5BF@1224,2TR4R@28211,COG1013@1,COG1013@2 NA|NA|NA C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit MAG.T12.39_00288 1282876.BAOK01000001_gene1844 2.8e-88 332.0 Alphaproteobacteria Bacteria 1N22F@1224,2U2V5@28211,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_00289 1207063.P24_16165 1.1e-128 466.5 Rhodospirillales pseI 2.5.1.56,2.5.1.97 ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 R01804,R04435,R09841 RC00159 ko00000,ko00001,ko01000 Bacteria 1MWG3@1224,2JRJX@204441,2TRA6@28211,COG2089@1,COG2089@2 NA|NA|NA M COG2089 Sialic acid synthase MAG.T12.39_00290 1292034.OR37_00253 2.3e-61 242.3 Caulobacterales 5.4.3.8 ko:K01845,ko:K07257 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1RG42@1224,2KIW7@204458,2UABZ@28211,COG1861@1,COG1861@2 NA|NA|NA M Cytidylyltransferase MAG.T12.39_00291 509190.Cseg_2681 6.3e-69 267.3 Caulobacterales Bacteria 1MWFM@1224,2KGC3@204458,2U5DR@28211,COG3819@1,COG3819@2 NA|NA|NA S Protein of unknown function (DUF969) MAG.T12.39_00292 509190.Cseg_2682 3.8e-99 368.2 Caulobacterales Bacteria 1MXGD@1224,2KFGG@204458,2TUDC@28211,COG3817@1,COG3817@2 NA|NA|NA S Protein of unknown function (DUF979) MAG.T12.39_00293 450851.PHZ_c1581 2.9e-121 441.8 Caulobacterales Bacteria 1MX6G@1224,2C57D@1,2KG7G@204458,2TTDU@28211,2Z7RS@2 NA|NA|NA S Protein of unknown function (DUF2891) MAG.T12.39_00294 1292034.OR37_02731 3.9e-162 578.6 Caulobacterales Bacteria 1MVMG@1224,2KFVS@204458,2TSGE@28211,COG0457@1,COG0457@2 NA|NA|NA S Sulfotransferase MAG.T12.39_00295 1449049.JONW01000005_gene1013 3.1e-272 944.5 Caulobacterales Bacteria 1QUTW@1224,2KFR5@204458,2TW7F@28211,COG1629@1,COG1629@2 NA|NA|NA P receptor MAG.T12.39_00296 450851.PHZ_c0559 1.9e-116 425.6 Caulobacterales sua5 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1MVPM@1224,2KF1M@204458,2TRIM@28211,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine MAG.T12.39_00297 450851.PHZ_c0560 1.4e-166 592.8 Caulobacterales Bacteria 1MU6Y@1224,2KFKP@204458,2TRYI@28211,COG0277@1,COG0277@2 NA|NA|NA C PFAM FAD linked oxidase domain protein MAG.T12.39_00298 450851.PHZ_c0561 4.7e-87 327.8 Caulobacterales yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 ko:K09861 ko00000 Bacteria 1MUAF@1224,2KG6A@204458,2TS11@28211,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family MAG.T12.39_00300 69395.JQLZ01000004_gene735 2.2e-38 164.9 Caulobacterales ko:K10947 ko00000,ko03000 Bacteria 1N0PH@1224,2KGQR@204458,2UBD4@28211,COG1695@1,COG1695@2 NA|NA|NA K PFAM transcriptional regulator PadR family protein MAG.T12.39_00301 450851.PHZ_c1648 7.4e-50 203.8 Caulobacterales Bacteria 1RAQB@1224,2KG8T@204458,2U62C@28211,COG4709@1,COG4709@2 NA|NA|NA S Protein of unknown function (DUF1700) MAG.T12.39_00302 573065.Astex_1584 8.8e-35 154.1 Caulobacterales Bacteria 1REST@1224,2KGVT@204458,2U7ZP@28211,COG4709@1,COG4709@2 NA|NA|NA S Putative auto-transporter adhesin, head GIN domain MAG.T12.39_00303 1282361.ABAC402_07805 3.3e-33 148.3 Caulobacterales ko:K03098 ko00000,ko04147 Bacteria 1N0MF@1224,2KH03@204458,2UECA@28211,COG3040@1,COG3040@2 NA|NA|NA M Lipocalin-like domain MAG.T12.39_00304 366602.Caul_4412 4.8e-100 370.9 Caulobacterales Bacteria 1MWGK@1224,2KFD8@204458,2TVQ8@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_00305 450851.PHZ_c2936 1.2e-174 619.4 Caulobacterales metZ GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K10764 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 iNJ661.Rv0391 Bacteria 1MU57@1224,2KF81@204458,2TTMF@28211,COG0626@1,COG0626@2 NA|NA|NA E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide MAG.T12.39_00306 190650.CC_2237 3e-150 538.1 Caulobacterales dcd 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVDH@1224,2KFP3@204458,2TR5U@28211,COG0717@1,COG0717@2 NA|NA|NA F 2-deoxycytidine 5-triphosphate deaminase MAG.T12.39_00307 1173028.ANKO01000018_gene1175 5.3e-44 184.9 Oscillatoriales Bacteria 1G294@1117,1HA12@1150,2CA76@1,2Z8DQ@2 NA|NA|NA MAG.T12.39_00309 190650.CC_0113 8.6e-47 193.0 Caulobacterales Bacteria 1N1D4@1224,2KJTF@204458,2UGZ0@28211,COG0346@1,COG0346@2 NA|NA|NA E COG0346 Lactoylglutathione lyase and related lyases MAG.T12.39_00310 1449076.JOOE01000002_gene1451 4.7e-95 354.8 Sphingomonadales phy 3.1.3.8 ko:K01083 ko00562,map00562 R03371 RC00078 ko00000,ko00001,ko01000 Bacteria 1MVTA@1224,2JZUY@204457,2TUDJ@28211,COG4247@1,COG4247@2 NA|NA|NA I 3-phytase MAG.T12.39_00311 1449076.JOOE01000002_gene1450 0.0 1333.9 Sphingomonadales Bacteria 1MUWN@1224,2KD9E@204457,2TUC0@28211,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P Outer membrane protein beta-barrel family MAG.T12.39_00312 506534.Rhein_1694 2.3e-105 389.0 Gammaproteobacteria Bacteria 1R5UC@1224,1RUM4@1236,COG2227@1,COG2227@2 NA|NA|NA H Nodulation protein S (NodS) MAG.T12.39_00313 909663.KI867150_gene1735 1.8e-112 412.5 Deltaproteobacteria 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1PPCS@1224,2WWA6@28221,430SX@68525,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity MAG.T12.39_00314 561230.PC1_2566 1.5e-140 505.8 Pectobacterium 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1MT6T@122277,1N5AZ@1224,1T04N@1236,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity MAG.T12.39_00315 351016.RAZWK3B_05787 2e-65 255.8 Proteobacteria Bacteria 1NIE0@1224,COG4122@1,COG4122@2 NA|NA|NA S PFAM WbqC-like protein family MAG.T12.39_00316 1545915.JROG01000004_gene2463 6.4e-43 180.3 Sphingomonadales Bacteria 1RBET@1224,2K5UC@204457,2U5TM@28211,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T12.39_00317 573065.Astex_0194 6.8e-25 120.6 Alphaproteobacteria MA20_31455 2.7.13.3 ko:K02487,ko:K03407,ko:K06596 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1N0NS@1224,2TV2S@28211,COG0784@1,COG0784@2 NA|NA|NA T Response regulator receiver MAG.T12.39_00318 1081640.AGFU01000002_gene334 8.9e-87 327.0 Sphingomonadales Bacteria 1NE89@1224,2DC09@1,2JZV2@204457,2UIS7@28211,2ZC6D@2 NA|NA|NA MAG.T12.39_00319 450851.PHZ_c2775 4.7e-149 534.3 Caulobacterales Bacteria 1MUBH@1224,2KF9A@204458,2TVBB@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM acyl-CoA dehydrogenase domain protein MAG.T12.39_00320 450851.PHZ_c2774 1.2e-163 582.8 Caulobacterales Bacteria 1MVJC@1224,2KFB8@204458,2TUVB@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM acyl-CoA dehydrogenase domain protein MAG.T12.39_00321 1090320.KB900605_gene2236 9.5e-148 530.0 Sphingomonadales Bacteria 1MVJC@1224,2K24U@204457,2TUVB@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T12.39_00322 1090320.KB900605_gene2236 3.7e-144 518.1 Sphingomonadales Bacteria 1MVJC@1224,2K24U@204457,2TUVB@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T12.39_00323 450851.PHZ_c2773 3.3e-188 664.5 Caulobacterales MA20_22780 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVJC@1224,2KFB8@204458,2TUVB@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM acyl-CoA dehydrogenase domain protein MAG.T12.39_00324 450851.PHZ_c2772 2.8e-201 708.4 Caulobacterales mprF 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 Bacteria 1QVFK@1224,2KFET@204458,2TWDQ@28211,COG2898@1,COG2898@2 NA|NA|NA S Uncharacterised conserved protein (DUF2156) MAG.T12.39_00325 69395.JQLZ01000001_gene2721 5.2e-17 93.2 Caulobacterales Bacteria 1NM79@1224,2EMIR@1,2KHGP@204458,2UJTM@28211,33F7B@2 NA|NA|NA MAG.T12.39_00326 366602.Caul_1450 2.8e-37 164.1 Caulobacterales ko:K07126,ko:K13582 ko04112,map04112 ko00000,ko00001 Bacteria 1MWPA@1224,2KG2C@204458,2TR2B@28211,COG0790@1,COG0790@2 NA|NA|NA D Sel1-like repeats. MAG.T12.39_00327 69395.JQLZ01000001_gene2719 2.8e-106 391.7 Caulobacterales MA20_19835 ko:K07090 ko00000 Bacteria 1MWX2@1224,2KF93@204458,2TRIC@28211,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T12.39_00328 450851.PHZ_c2768 5.7e-57 227.6 Caulobacterales MA20_19830 Bacteria 1NHGB@1224,2AFUA@1,2KG08@204458,2TQWW@28211,315WQ@2 NA|NA|NA S Putative transmembrane protein (Alph_Pro_TM) MAG.T12.39_00329 450851.PHZ_c2767 4.3e-26 124.4 Caulobacterales VPA1252 Bacteria 1PSCU@1224,2DR7N@1,2KJCJ@204458,2UVQP@28211,33AJV@2 NA|NA|NA S Protein of unknown function (DUF3429) MAG.T12.39_00330 366602.Caul_1453 9.9e-68 263.5 Caulobacterales MA20_22045 ko:K06953 ko00000 Bacteria 1RC5G@1224,2KG9F@204458,2TU2T@28211,COG1407@1,COG1407@2 NA|NA|NA S ICC-like phosphoesterases MAG.T12.39_00331 450851.PHZ_c2761 0.0 1281.9 Caulobacterales lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1MUSW@1224,2KFMM@204458,2TR7V@28211,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase MAG.T12.39_00332 463191.SSEG_10619 5.9e-65 254.6 Actinobacteria Bacteria 2I8HN@201174,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T12.39_00333 1463820.JOGW01000012_gene3788 4.2e-27 127.1 Actinobacteria Bacteria 2DQWS@1,2IQUC@201174,32UPZ@2 NA|NA|NA MAG.T12.39_00334 450851.PHZ_c2755 0.0 1219.9 Caulobacterales dinG 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 1MVCU@1224,2KG7V@204458,2TUKS@28211,COG1199@1,COG1199@2 NA|NA|NA KL helicase MAG.T12.39_00335 1336243.JAEA01000003_gene2402 2.3e-24 118.2 Methylobacteriaceae emrE ko:K03297 ko00000,ko02000 2.A.7.1 Bacteria 1JV9C@119045,1MZ54@1224,2UBXR@28211,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein MAG.T12.39_00336 69395.JQLZ01000002_gene1173 2.3e-109 402.1 Caulobacterales aroA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 1QTZA@1224,2KGS3@204458,2TS12@28211,COG0287@1,COG0287@2 NA|NA|NA E prephenate dehydrogenase MAG.T12.39_00337 59538.XP_005973945.1 8.1e-146 523.5 Metazoa 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Metazoa 38DTP@33154,3BSZS@33208,COG0079@1,KOG0633@2759 NA|NA|NA E Aminotransferase class I and II MAG.T12.39_00338 450851.PHZ_c2750 3.7e-87 328.2 Caulobacterales 2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5 ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R03084,R03460,R06602 RC00350,RC00848,RC01549,RC02148,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWTP@1224,2KGJC@204458,2TV3Z@28211,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase MAG.T12.39_00339 1449049.JONW01000006_gene2841 1.9e-255 888.6 Caulobacterales 3.5.1.97 ko:K07116 ko00000,ko01000 Bacteria 1MVMH@1224,2KG74@204458,2TS4D@28211,COG2366@1,COG2366@2 NA|NA|NA S Penicillin amidase MAG.T12.39_00340 450851.PHZ_c1911 1.7e-207 728.8 Caulobacterales MA20_07830 ko:K10215 ko00627,ko01120,map00627,map01120 R07836,R07837 RC02100,RC03121 ko00000,ko00001,ko01000 Bacteria 1MU71@1224,2KG5Q@204458,2TV2E@28211,COG2072@1,COG2072@2 NA|NA|NA P Flavin-binding monooxygenase-like MAG.T12.39_00341 69395.JQLZ01000002_gene1170 5.2e-43 181.8 Caulobacterales MA20_20440 Bacteria 1MYJZ@1224,2KGXZ@204458,2V9PZ@28211,COG4093@1,COG4093@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2125) MAG.T12.39_00342 450851.PHZ_c0626 4.6e-65 254.2 Caulobacterales chaC ko:K07232 ko00000 Bacteria 1QA7D@1224,2KHSX@204458,2U7C6@28211,COG3703@1,COG3703@2 NA|NA|NA P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides MAG.T12.39_00343 450851.PHZ_c0627 5.7e-76 290.8 Caulobacterales plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MY51@1224,2KGAR@204458,2TT3P@28211,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T12.39_00344 450851.PHZ_c0628 5e-60 237.7 Caulobacterales MA20_20455 Bacteria 1RHMV@1224,2KGI6@204458,2U957@28211,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain MAG.T12.39_00345 1382303.JPOM01000001_gene2001 1.4e-22 113.6 Caulobacterales ftsX ko:K09811 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1MXKQ@1224,2KFRD@204458,2TSNT@28211,COG2177@1,COG2177@2 NA|NA|NA D Cell division protein MAG.T12.39_00346 1479238.JQMZ01000001_gene155 1.7e-40 172.9 Hyphomonadaceae ftsE GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1MVQ4@1224,2TS9Y@28211,43WPT@69657,COG2884@1,COG2884@2 NA|NA|NA D cell division ATP-binding protein FtsE MAG.T12.39_00347 190650.CC_2215 3.9e-29 135.6 Caulobacterales Bacteria 1N9PP@1224,2E521@1,2KGRT@204458,2UG1E@28211,32ZVA@2 NA|NA|NA S MJ0042 family finger-like MAG.T12.39_00348 1449049.JONW01000012_gene265 5.8e-47 194.1 Caulobacterales hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 Bacteria 1NRT8@1224,2KGG4@204458,2TTN7@28211,COG0634@1,COG0634@2 NA|NA|NA F phosphoribosyltransferase MAG.T12.39_00349 450851.PHZ_c0634 6e-180 637.1 Caulobacterales lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1517 Bacteria 1MUA6@1224,2KFUF@204458,2TQPB@28211,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T12.39_00351 1382303.JPOM01000001_gene374 7.1e-200 703.4 Caulobacterales argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUTU@1224,2KFRS@204458,2TR4H@28211,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase MAG.T12.39_00352 450851.PHZ_c0636 1.8e-49 202.6 Caulobacterales tlpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MZ5J@1224,2KH4D@204458,2TR0C@28211,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T12.39_00354 1996.JOFO01000048_gene2714 3.8e-81 308.9 Streptosporangiales Bacteria 2HG6N@201174,4EGR6@85012,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T12.39_00356 1333998.M2A_2255 1.4e-228 798.9 Alphaproteobacteria MA20_23085 ko:K10215 ko00627,ko01120,map00627,map01120 R07836,R07837 RC02100,RC03121 ko00000,ko00001,ko01000 Bacteria 1MU71@1224,2TV2E@28211,COG2072@1,COG2072@2 NA|NA|NA P Flavoprotein involved in K transport MAG.T12.39_00357 450851.PHZ_c2978 0.0 1117.8 Caulobacterales pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1MWKS@1224,2KG4H@204458,2TQV8@28211,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily MAG.T12.39_00358 450851.PHZ_c2977 5.4e-158 563.9 Caulobacterales pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176 Bacteria 1MVD7@1224,2KFJS@204458,2TS2T@28211,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily MAG.T12.39_00359 450851.PHZ_c2976 3.5e-50 204.1 Caulobacterales rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RGU2@1224,2KGMI@204458,2U756@28211,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit MAG.T12.39_00360 190650.CC_1046 1.3e-25 121.7 Caulobacterales rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1N6V4@1224,2KH9H@204458,2UF6K@28211,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family MAG.T12.39_00361 1382303.JPOM01000001_gene1419 4e-130 471.5 Caulobacterales ko:K08153 M00717 ko00000,ko00002,ko02000 2.A.1.2.8 Bacteria 1MVSH@1224,2KFCU@204458,2TUEW@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_00362 450851.PHZ_c2972 2.6e-86 324.7 Caulobacterales infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1RDD2@1224,2KFQQ@204458,2U58Z@28211,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins MAG.T12.39_00363 450851.PHZ_c2971 1.3e-118 433.0 Caulobacterales ko:K02849 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 1MXA2@1224,2KG40@204458,2TUTN@28211,COG0859@1,COG0859@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) MAG.T12.39_00364 69395.JQLZ01000001_gene2944 4.4e-126 458.0 Caulobacterales capM Bacteria 1MUTA@1224,2KFUU@204458,2TSPN@28211,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 MAG.T12.39_00365 1292034.OR37_03533 1.1e-93 349.7 Caulobacterales MA20_24420 ko:K06889,ko:K07000 ko00000 Bacteria 1MX88@1224,2KFTQ@204458,2TSRE@28211,COG1073@1,COG1073@2 NA|NA|NA S Alpha beta hydrolase MAG.T12.39_00366 450851.PHZ_c2967 3.2e-70 271.9 Caulobacterales yeeZ 1.5.5.1 ko:K00311 ko00000,ko01000 Bacteria 1MWVJ@1224,2KFB6@204458,2TRDY@28211,COG0451@1,COG0451@2 NA|NA|NA GM epimerase MAG.T12.39_00367 450851.PHZ_c2965 1.9e-129 468.8 Caulobacterales galU 2.7.7.9,5.4.2.8 ko:K00963,ko:K01840 ko00040,ko00051,ko00052,ko00500,ko00520,ko01100,ko01110,ko01130,map00040,map00051,map00052,map00500,map00520,map01100,map01110,map01130 M00114,M00129,M00361,M00362,M00549 R00289,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV5F@1224,2KFMW@204458,2TRT6@28211,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase MAG.T12.39_00368 864051.BurJ1DRAFT_0302 9.3e-94 350.1 unclassified Burkholderiales Bacteria 1KK8X@119065,1MUAS@1224,2VHM0@28216,COG0384@1,COG0384@2 NA|NA|NA S phenazine biosynthesis protein PhzF family MAG.T12.39_00369 1424334.W822_22455 8.1e-53 213.8 Alcaligenaceae paiB ko:K07734 ko00000,ko03000 Bacteria 1N1B9@1224,2VRAJ@28216,3T20R@506,COG2808@1,COG2808@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00370 1449049.JONW01000005_gene1779 8.7e-246 856.3 Caulobacterales glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4K@1224,2KG1W@204458,2TQPM@28211,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source MAG.T12.39_00371 450851.PHZ_c2962 4.2e-205 720.7 Caulobacterales glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSBO_1134.SBO_3206 Bacteria 1MU24@1224,2KG4R@204458,2TQWH@28211,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate MAG.T12.39_00372 1470591.BW41_02539 1.1e-109 403.7 Sphingomonadales citN ko:K03300 ko00000 2.A.11 Bacteria 1N25B@1224,2K0BJ@204457,2TT6T@28211,COG2851@1,COG2851@2 NA|NA|NA C Citrate transporter MAG.T12.39_00373 1100720.ALKN01000036_gene856 4.1e-70 272.7 Betaproteobacteria 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1QWB0@1224,2WIA8@28216,COG5549@1,COG5549@2 NA|NA|NA O Peptidoglycan-binding domain 1 protein MAG.T12.39_00374 450851.PHZ_c2961 2.4e-197 694.9 Caulobacterales rkpK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW5U@1224,2KG3N@204458,2TREV@28211,COG1004@1,COG1004@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T12.39_00375 450851.PHZ_c2960 1e-236 825.9 Caulobacterales algC 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUA5@1224,2KF2W@204458,2TRIJ@28211,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II MAG.T12.39_00376 450851.PHZ_c2959 5.1e-120 437.6 Caulobacterales kdsD 5.3.1.13 ko:K03281,ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 2.A.49 iAF987.Gmet_1278 Bacteria 1MUXD@1224,2KFTV@204458,2TU5X@28211,COG0517@1,COG0517@2,COG0794@1,COG0794@2 NA|NA|NA M Belongs to the SIS family. GutQ KpsF subfamily MAG.T12.39_00377 450851.PHZ_c2958 3.3e-13 80.9 Caulobacterales Bacteria 1NIE5@1224,2DS4A@1,2KHHT@204458,2UMCA@28211,33EG0@2 NA|NA|NA MAG.T12.39_00378 450851.PHZ_c2957 2.6e-105 388.3 Caulobacterales gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1MUVE@1224,2KEXT@204458,2TSQ0@28211,COG0588@1,COG0588@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily MAG.T12.39_00379 450851.PHZ_c2956 1.1e-39 169.5 Caulobacterales ribD 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUWT@1224,2KGZ5@204458,2TR70@28211,COG0117@1,COG0117@2 NA|NA|NA H Cytidine and deoxycytidylate deaminase zinc-binding region MAG.T12.39_00380 450851.PHZ_c2955 9.3e-29 134.8 Caulobacterales Bacteria 1N7U9@1224,2KFEQ@204458,2U1FV@28211,COG1357@1,COG1357@2 NA|NA|NA S PFAM pentapeptide repeat protein MAG.T12.39_00381 450851.PHZ_c2953 2.9e-65 254.6 Caulobacterales ibpA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K04080,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1RH2X@1224,2KGFP@204458,2U96D@28211,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T12.39_00382 450851.PHZ_c2950 6.2e-22 110.2 Caulobacterales Bacteria 1PBWT@1224,2KH6J@204458,2V6E3@28211,COG3255@1,COG3255@2 NA|NA|NA I PFAM Sterol-binding domain protein MAG.T12.39_00383 450851.PHZ_c2949 1.6e-97 362.8 Caulobacterales pldB GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049 Bacteria 1MWDA@1224,2KF0C@204458,2TSZ4@28211,COG2267@1,COG2267@2 NA|NA|NA I Alpha beta hydrolase MAG.T12.39_00384 366602.Caul_1220 2.3e-97 362.1 Caulobacterales hisN 3.1.3.15,3.1.3.25 ko:K01092,ko:K05602 ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070 M00026,M00131 R01185,R01186,R01187,R03013 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1PPJ0@1224,2KFY0@204458,2TQTX@28211,COG0483@1,COG0483@2 NA|NA|NA G Histidinol-phosphate phosphatase MAG.T12.39_00385 1121123.AUAO01000001_gene1022 7.1e-18 96.7 Caulobacterales phrR Bacteria 1RDBW@1224,2KGII@204458,2U7CY@28211,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00386 450851.PHZ_c2946 3.9e-117 427.9 Caulobacterales msbB 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MVNI@1224,2KFRE@204458,2TS2H@28211,COG1560@1,COG1560@2 NA|NA|NA M lipid A biosynthesis acyltransferase MAG.T12.39_00387 69395.JQLZ01000002_gene1206 1.6e-79 302.8 Caulobacterales 3.4.24.75 ko:K08259 ko00000,ko01000,ko01002,ko01011 Bacteria 1MY2X@1224,2KFA7@204458,2U6AR@28211,COG0739@1,COG0739@2 NA|NA|NA M peptidase MAG.T12.39_00388 450851.PHZ_c2945 9.5e-19 99.0 Caulobacterales MA20_05765 Bacteria 1N7PA@1224,2KHA8@204458,2UFTN@28211,COG3908@1,COG3908@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2093) MAG.T12.39_00389 450851.PHZ_c2944 1.1e-174 619.8 Caulobacterales xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUA4@1224,2KF2B@204458,2TR1R@28211,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T12.39_00390 450851.PHZ_c2943 1.3e-69 269.2 Caulobacterales gcrA ko:K13583 ko04112,map04112 ko00000,ko00001 Bacteria 1RHI6@1224,2KGJW@204458,2TS7F@28211,COG5352@1,COG5352@2 NA|NA|NA S PFAM GcrA cell cycle regulator MAG.T12.39_00391 702113.PP1Y_Mpl6083 1e-16 93.6 Sphingomonadales Bacteria 1RI8R@1224,2K84A@204457,2UJBV@28211,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T12.39_00392 450851.PHZ_c2942 2.3e-108 398.7 Caulobacterales yadH ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUH1@1224,2KFND@204458,2TQSY@28211,COG0842@1,COG0842@2 NA|NA|NA V Transport permease protein MAG.T12.39_00393 450851.PHZ_c2939 9.8e-169 599.7 Caulobacterales argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MV3C@1224,2KFAE@204458,2TSGT@28211,COG4992@1,COG4992@2 NA|NA|NA E acetylornithine MAG.T12.39_00394 1449049.JONW01000012_gene191 8e-131 473.4 Caulobacterales argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUFM@1224,2KFGS@204458,2TR81@28211,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline MAG.T12.39_00395 1449049.JONW01000012_gene188 6.9e-122 443.7 Caulobacterales hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1MUMU@1224,2KFP8@204458,2TTUR@28211,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress MAG.T12.39_00396 450851.PHZ_c0563 5.1e-152 543.9 Caulobacterales 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MU2F@1224,2KG4N@204458,2U3PD@28211,COG2070@1,COG2070@2 NA|NA|NA S PFAM 2-nitropropane dioxygenase NPD MAG.T12.39_00397 566466.NOR53_2549 1.8e-75 289.3 unclassified Gammaproteobacteria Bacteria 1J7N7@118884,1R413@1224,1S3TR@1236,COG1028@1,COG1028@2 NA|NA|NA IQ related to short-chain alcohol dehydrogenases MAG.T12.39_00398 366602.Caul_0437 4.7e-67 261.9 Alphaproteobacteria ko:K19577 ko00000,ko02000 2.A.1.2.65 Bacteria 1RAYQ@1224,2UABD@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily MAG.T12.39_00399 450851.PHZ_c0578 1.2e-117 429.9 Caulobacterales mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUD4@1224,2KFF7@204458,2TQVX@28211,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase MAG.T12.39_00400 450851.PHZ_c0579 2.8e-46 191.8 Caulobacterales MA20_42435 Bacteria 1RJ74@1224,2KGV4@204458,2U9CZ@28211,COG5389@1,COG5389@2 NA|NA|NA S Protein of unknown function (DUF721) MAG.T12.39_00401 450851.PHZ_c0580 1.3e-73 282.7 Caulobacterales dsbA Bacteria 1RFF4@1224,2KGJX@204458,2U5BN@28211,COG1651@1,COG1651@2 NA|NA|NA O DSBA oxidoreductase MAG.T12.39_00402 1292034.OR37_00601 4.4e-299 1034.2 Caulobacterales smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529 ko00000,ko03036 Bacteria 1MUAQ@1224,2KFD5@204458,2TRQG@28211,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T12.39_00403 450851.PHZ_c0583 9e-20 102.4 Caulobacterales atpI ko:K02116 ko00000,ko00194 3.A.2.1 Bacteria 1NHIS@1224,2KHA6@204458,2UH8M@28211,COG5336@1,COG5336@2 NA|NA|NA S function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex MAG.T12.39_00404 450851.PHZ_c0584 3.4e-90 338.2 Caulobacterales atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 1MV87@1224,2KFXM@204458,2TRNV@28211,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane MAG.T12.39_00405 450851.PHZ_c0585 2.2e-26 124.4 Caulobacterales atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1MZBU@1224,2KH88@204458,2UFPN@28211,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T12.39_00406 588932.JHOF01000027_gene1509 7e-24 117.5 Caulobacterales atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1MZGU@1224,2KGUT@204458,2UBVW@28211,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T12.39_00407 450851.PHZ_c0587 2.1e-35 155.6 Caulobacterales atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1N0P5@1224,2KGT1@204458,2U5DD@28211,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T12.39_00408 1449049.JONW01000005_gene1445 1.8e-29 135.6 Caulobacterales Bacteria 1N95H@1224,2DP00@1,2KHDE@204458,2UGPJ@28211,32ZZT@2 NA|NA|NA MAG.T12.39_00409 509190.Cseg_0338 1.2e-248 865.5 Caulobacterales gcvPB 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 Bacteria 1MUDP@1224,2KFPB@204458,2TSFF@28211,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MAG.T12.39_00410 450851.PHZ_c0590 1.4e-192 679.1 Caulobacterales gcvPA GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVC1@1224,2KFNP@204458,2TR6C@28211,COG0403@1,COG0403@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MAG.T12.39_00411 190650.CC_3354 4.4e-48 197.2 Caulobacterales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1RGV7@1224,2KGNV@204458,2U9BY@28211,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein MAG.T12.39_00412 1292034.OR37_00615 3.2e-134 485.0 Caulobacterales gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10 ko:K00600,ko:K00605 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R01221,R02300,R04125,R09099 RC00022,RC00069,RC00112,RC00183,RC01583,RC02834,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV96@1224,2KFAF@204458,2TRN4@28211,COG0404@1,COG0404@2 NA|NA|NA E Glycine cleavage system T protein MAG.T12.39_00413 450851.PHZ_c2895 3.7e-241 840.9 Caulobacterales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 1MU4J@1224,2KFTD@204458,2TS3Y@28211,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase MAG.T12.39_00414 450851.PHZ_c2894 1.5e-65 256.1 Caulobacterales Bacteria 1RBIS@1224,28PM9@1,2KGEC@204458,2U6Q4@28211,2ZCAC@2 NA|NA|NA MAG.T12.39_00415 450851.PHZ_c2893 2.2e-123 448.7 Caulobacterales ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 1MU7G@1224,2KFGM@204458,2TRNR@28211,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T12.39_00416 745776.DGo_CA0345 9e-22 110.9 Deinococcus-Thermus ymdC 2.7.1.87,2.7.1.95 ko:K00897,ko:K10673,ko:K19272,ko:K19299,ko:K19300 M00766 br01600,ko00000,ko00002,ko01000,ko01504 Bacteria 1WMRR@1297,COG3231@1,COG3231@2 NA|NA|NA J Belongs to the aminoglycoside phosphotransferase family MAG.T12.39_00417 450851.PHZ_c2890 9.7e-133 479.9 Caulobacterales thrB 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUKJ@1224,2KG5A@204458,2TS6D@28211,COG2334@1,COG2334@2 NA|NA|NA F Belongs to the pseudomonas-type ThrB family MAG.T12.39_00418 450851.PHZ_c2889 4.5e-63 247.3 Caulobacterales rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1RCZ1@1224,2KGMX@204458,2U7C4@28211,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T12.39_00419 450851.PHZ_c2885 9.2e-14 83.6 Alphaproteobacteria ywoH ko:K06075 ko00000,ko03000 Bacteria 1RD9U@1224,2U7NF@28211,COG1846@1,COG1846@2 NA|NA|NA K transcriptional regulator MAG.T12.39_00420 450851.PHZ_c0565 9.8e-29 133.3 Caulobacterales ybbJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07340 ko00000 Bacteria 1PVR4@1224,2KGY1@204458,2UEDQ@28211,COG1585@1,COG1585@2 NA|NA|NA OU NfeD-like C-terminal, partner-binding MAG.T12.39_00421 450851.PHZ_c0564 4.9e-96 357.8 Caulobacterales qmcA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MUM8@1224,2KEYR@204458,2TRUY@28211,COG0330@1,COG0330@2 NA|NA|NA O PFAM band 7 protein MAG.T12.39_00423 450851.PHZ_c2098 3.7e-71 275.0 Caulobacterales ko:K07148 ko00000 Bacteria 1MWHW@1224,2KGA8@204458,2U310@28211,COG2311@1,COG2311@2 NA|NA|NA S Protein of unknown function (DUF418) MAG.T12.39_00424 450851.PHZ_c2098 2.7e-46 191.4 Caulobacterales ko:K07148 ko00000 Bacteria 1MWHW@1224,2KGA8@204458,2U310@28211,COG2311@1,COG2311@2 NA|NA|NA S Protein of unknown function (DUF418) MAG.T12.39_00425 450851.PHZ_c0577 1.1e-179 636.0 Caulobacterales ccrM 2.1.1.72 ko:K00571,ko:K13581 ko04112,map04112 ko00000,ko00001,ko01000,ko02048 Bacteria 1MX9M@1224,2KFGB@204458,2TSW9@28211,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family MAG.T12.39_00426 1121123.AUAO01000002_gene553 7.4e-80 303.5 Caulobacterales rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1RA65@1224,2KGDU@204458,2U73X@28211,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T12.39_00427 450851.PHZ_c0575 6.4e-73 280.4 Caulobacterales tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1R9X5@1224,2KGD2@204458,2TUP5@28211,COG2818@1,COG2818@2 NA|NA|NA L DNA-3-methyladenine glycosylase MAG.T12.39_00428 450851.PHZ_c0574 2.9e-68 265.4 Caulobacterales ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 ko:K06980 ko00000,ko03016 Bacteria 1N852@1224,2KFSW@204458,2TR8J@28211,COG0354@1,COG0354@2 NA|NA|NA S Belongs to the GcvT family MAG.T12.39_00429 450851.PHZ_c0573 1e-112 413.3 Caulobacterales ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 1MXA2@1224,2KFY9@204458,2TSXD@28211,COG0859@1,COG0859@2 NA|NA|NA M PFAM glycosyl transferase family 9 MAG.T12.39_00430 1449049.JONW01000009_gene4542 0.0 2124.4 Caulobacterales yapH ko:K13735,ko:K19231 ko05100,map05100 ko00000,ko00001,ko02000 1.B.12 Bacteria 1MXIP@1224,2KI7D@204458,2TTVB@28211,COG2911@1,COG2911@2,COG3210@1,COG3210@2,COG5492@1,COG5492@2 NA|NA|NA U haemagglutination activity domain MAG.T12.39_00431 1144307.PMI04_04422 5.3e-123 448.4 Alphaproteobacteria Bacteria 1PRBP@1224,2U1SN@28211,COG2831@1,COG2831@2 NA|NA|NA U Haemolysin secretion/activation protein ShlB/FhaC/HecB MAG.T12.39_00432 1280947.HY30_16405 6e-57 228.0 Bacteria Bacteria COG5031@1,COG5031@2 NA|NA|NA H ubiquinone biosynthetic process MAG.T12.39_00436 450851.PHZ_c1209 3.3e-82 311.6 Caulobacterales rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K22132 ko00000,ko01000,ko03009,ko03016 Bacteria 1MWCM@1224,2KGAS@204458,2TUG7@28211,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T12.39_00437 1248916.ANFY01000003_gene611 3.9e-205 720.7 Sphingomonadales 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU2V@1224,2KCQC@204457,2TSK3@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain MAG.T12.39_00438 1248916.ANFY01000018_gene1570 8.1e-119 433.7 Sphingomonadales ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 1MVG0@1224,2KD7H@204457,2TRU9@28211,COG3618@1,COG3618@2 NA|NA|NA S amidohydrolase MAG.T12.39_00439 190650.CC_1237 3.9e-59 235.0 Caulobacterales terC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1PN8B@1224,2KF4E@204458,2TUV5@28211,COG0861@1,COG0861@2 NA|NA|NA P PFAM Integral membrane protein TerC MAG.T12.39_00440 450851.PHZ_c1207 6.2e-273 946.4 Caulobacterales metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MUBY@1224,2KFCM@204458,2TQKA@28211,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation MAG.T12.39_00442 1449049.JONW01000012_gene19 9e-36 156.8 Caulobacterales ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1MZGS@1224,2KGUM@204458,2UCUT@28211,COG3474@1,COG3474@2 NA|NA|NA C Cytochrome c MAG.T12.39_00443 450851.PHZ_c1187 0.0 1338.9 Caulobacterales acrB ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 Bacteria 1MU48@1224,2KFKZ@204458,2TQT0@28211,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T12.39_00444 450851.PHZ_c1186 1.2e-106 393.3 Caulobacterales ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MUFW@1224,2KFYW@204458,2U2CU@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T12.39_00445 450851.PHZ_c1185 9.4e-125 453.0 Caulobacterales 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 R02262 RC00603,RC00604 ko00000,ko00001,ko01000 Bacteria 1MWP9@1224,2KFHT@204458,2TRMV@28211,COG0235@1,COG0235@2 NA|NA|NA G PFAM class II aldolase adducin family protein MAG.T12.39_00446 1292034.OR37_02222 4.4e-187 661.0 Caulobacterales glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1MUP7@1224,2KFG4@204458,2TRD7@28211,COG0554@1,COG0554@2 NA|NA|NA H Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate MAG.T12.39_00447 450851.PHZ_c1181 5.5e-102 377.9 Caulobacterales Bacteria 1R3VY@1224,2KFYZ@204458,2TVFN@28211,COG5330@1,COG5330@2 NA|NA|NA S Uncharacterised protein conserved in bacteria (DUF2336) MAG.T12.39_00448 190650.CC_1221 2.1e-100 372.1 Caulobacterales nadK 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1MUBC@1224,2KFFH@204458,2TSKN@28211,COG0061@1,COG0061@2 NA|NA|NA H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP MAG.T12.39_00449 1121124.JNIX01000007_gene429 8.8e-35 153.3 Caulobacterales MA20_31460 Bacteria 1NENQ@1224,2KGRV@204458,2TSW1@28211,COG2198@1,COG2198@2 NA|NA|NA T Histidine kinase MAG.T12.39_00450 450851.PHZ_c1178 2.9e-97 361.7 Caulobacterales MA20_35615 Bacteria 1NTFG@1224,2KGB5@204458,2U0I4@28211,COG0494@1,COG0494@2 NA|NA|NA L Hydrolase MAG.T12.39_00451 450851.PHZ_c1177 6.2e-103 380.9 Caulobacterales MA20_31465 Bacteria 1MXBZ@1224,2KFQW@204458,2TT9C@28211,COG5330@1,COG5330@2 NA|NA|NA S Uncharacterised protein conserved in bacteria (DUF2336) MAG.T12.39_00452 450851.PHZ_c1175 1.4e-159 569.3 Caulobacterales hadA 2.8.3.17,2.8.3.24 ko:K13607,ko:K20882 ko00960,map00960 R07796,R11462 RC00014,RC00131,RC00137 ko00000,ko00001,ko01000 Bacteria 1MWPB@1224,2KFDM@204458,2U1YE@28211,COG1804@1,COG1804@2 NA|NA|NA C CoA-transferase family III MAG.T12.39_00453 450851.PHZ_c1173 1.9e-73 282.7 Caulobacterales Bacteria 1MUMA@1224,2KFYM@204458,2TSA5@28211,COG0741@1,COG0741@2 NA|NA|NA M Lytic transglycosylase MAG.T12.39_00454 450851.PHZ_c1171 7.2e-169 600.1 Caulobacterales 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVAH@1224,2KFS7@204458,2TR02@28211,COG1960@1,COG1960@2 NA|NA|NA C Acyl-CoA dehydrogenase, C-terminal domain MAG.T12.39_00455 450851.PHZ_c1170 1.3e-63 250.4 Caulobacterales 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 R07463 RC01788 ko00000,ko00001,ko01000 Bacteria 1QDE0@1224,2KGWB@204458,2V8AE@28211,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase MAG.T12.39_00459 593907.Celgi_0702 2.3e-20 105.1 Actinobacteria Bacteria 2E49F@1,2IKMB@201174,32Z57@2 NA|NA|NA S Domain of unknown function (DUF4180) MAG.T12.39_00460 640513.Entas_2683 2.9e-09 68.2 Gammaproteobacteria Bacteria 1NIBH@1224,1SGGA@1236,2DSH2@1,33G3R@2 NA|NA|NA MAG.T12.39_00461 450851.PHZ_c1322 1.3e-44 186.0 Caulobacterales yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1RDHZ@1224,2KGF1@204458,2U98Y@28211,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA MAG.T12.39_00462 450851.PHZ_c1321 2.8e-150 538.1 Caulobacterales pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1MWAB@1224,2KEZH@204458,2TRHP@28211,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family MAG.T12.39_00463 287.DR97_2274 1.7e-62 245.7 Pseudomonas aeruginosa group yvdD_1 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1RD59@1224,1S4C3@1236,1YDY7@136841,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T12.39_00464 450851.PHZ_c1320 1.9e-170 605.5 Caulobacterales pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVXY@1224,2KFWA@204458,2TSTM@28211,COG0044@1,COG0044@2 NA|NA|NA F Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides MAG.T12.39_00465 450851.PHZ_c1319 3.9e-63 248.1 Caulobacterales plsY 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1RD4Z@1224,2KGBQ@204458,2U7BZ@28211,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP MAG.T12.39_00466 450851.PHZ_c1318 1.6e-112 412.9 Caulobacterales dprA ko:K04096 ko00000 Bacteria 1MVF6@1224,2KEZD@204458,2TRQE@28211,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA MAG.T12.39_00467 450851.PHZ_c1317 0.0 1271.5 Caulobacterales topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1MUFZ@1224,2KF1P@204458,2TRGN@28211,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone MAG.T12.39_00468 1292034.OR37_02423 4.9e-302 1043.5 Caulobacterales rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1MUS6@1224,2KFHH@204458,2TRC1@28211,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs MAG.T12.39_00469 1437448.AZRT01000053_gene401 6.1e-41 173.7 Brucellaceae ko:K08978,ko:K12962 ko01503,map01503 M00721 ko00000,ko00001,ko00002,ko01005,ko02000 2.A.7.2,2.A.7.22 Bacteria 1J2WW@118882,1RJ4E@1224,2U7CK@28211,COG2510@1,COG2510@2 NA|NA|NA S EamA-like transporter family MAG.T12.39_00470 450851.PHZ_c1314 7.4e-84 317.0 Caulobacterales MA20_36340 Bacteria 1N8EV@1224,2KGJ5@204458,2TTNV@28211,COG0494@1,COG0494@2 NA|NA|NA L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes MAG.T12.39_00471 1382303.JPOM01000001_gene713 1.9e-19 100.9 Caulobacterales rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1N6QV@1224,2KH6D@204458,2UF4D@28211,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family MAG.T12.39_00472 450851.PHZ_c1310 3.9e-158 564.7 Caulobacterales pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 ko00000,ko00001,ko00002,ko01000,ko02022 Bacteria 1R7HC@1224,2KFGH@204458,2TQQM@28211,COG0745@1,COG0745@2,COG2199@1,COG3706@2 NA|NA|NA T TIGRFAM diguanylate cyclase MAG.T12.39_00473 1449049.JONW01000011_gene2307 1.1e-54 219.2 Caulobacterales Bacteria 1RD7E@1224,2KGFJ@204458,2U745@28211,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver MAG.T12.39_00474 366602.Caul_1495 1.1e-60 240.0 Caulobacterales Bacteria 1RFSZ@1224,2KGVN@204458,2UBJU@28211,COG0647@1,COG0647@2 NA|NA|NA G UMP catabolic process MAG.T12.39_00475 450851.PHZ_c1305 2.8e-96 358.6 Caulobacterales mak 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MU94@1224,2KFXS@204458,2TRRU@28211,COG1940@1,COG1940@2 NA|NA|NA GK PFAM ROK family MAG.T12.39_00476 450851.PHZ_c1304 2e-148 532.3 Caulobacterales dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1MUUH@1224,2KG55@204458,2TSJN@28211,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII MAG.T12.39_00477 450851.PHZ_c1303 2.3e-48 198.0 Caulobacterales clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 1MZU8@1224,2KGPH@204458,2U982@28211,COG2127@1,COG2127@2 NA|NA|NA S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation MAG.T12.39_00478 450851.PHZ_c1302 0.0 1373.2 Caulobacterales clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K03694 ko00000,ko03110 Bacteria 1MV8B@1224,2KFKB@204458,2TQUZ@28211,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family MAG.T12.39_00479 388739.RSK20926_02152 5.6e-83 314.3 Roseobacter Bacteria 1NHIB@1224,2P2ZK@2433,2TT95@28211,COG3440@1,COG3440@2 NA|NA|NA V Domain of unknown function (DUF3883) MAG.T12.39_00480 450851.PHZ_c1985 2.7e-122 445.7 Caulobacterales norM ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 1MUAM@1224,2KFPY@204458,2TSDU@28211,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein MAG.T12.39_00481 450851.PHZ_c1348 9.7e-130 470.3 Caulobacterales rumA 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1MV3A@1224,2KFE4@204458,2TR40@28211,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family MAG.T12.39_00483 633149.Bresu_1824 1.5e-63 249.6 Caulobacterales tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1MWP5@1224,2KGM1@204458,2TRW9@28211,COG1189@1,COG1189@2 NA|NA|NA J FtsJ-like methyltransferase MAG.T12.39_00484 392499.Swit_2478 9.7e-09 66.6 Sphingomonadales Bacteria 1NKJ2@1224,2AA4J@1,2K6SY@204457,2UK6J@28211,30ZDH@2 NA|NA|NA MAG.T12.39_00485 573065.Astex_1050 2.2e-254 885.2 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QWER@1224,2KIFQ@204458,2TWXE@28211,COG4206@1,COG4206@2 NA|NA|NA H Outer membrane protein beta-barrel family MAG.T12.39_00486 573065.Astex_1051 5.6e-120 438.0 Caulobacterales Bacteria 1MX8C@1224,2KGI5@204458,2TSQ9@28211,COG3182@1,COG3182@2 NA|NA|NA S PepSY-associated TM region MAG.T12.39_00487 876044.IMCC3088_901 6.4e-68 264.2 Gammaproteobacteria Bacteria 1QVFN@1224,1T2G5@1236,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase-like superfamily MAG.T12.39_00488 251221.35212255 3e-30 139.4 Cyanobacteria Bacteria 1GD7B@1117,COG4188@1,COG4188@2 NA|NA|NA S Platelet-activating factor acetylhydrolase, isoform II MAG.T12.39_00489 402881.Plav_2206 3.8e-213 747.7 Rhodobiaceae 6.2.1.42 ko:K00666,ko:K18688 ko00000,ko01000,ko01004 Bacteria 1JQM7@119043,1MVJ1@1224,2TUQ9@28211,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase MAG.T12.39_00490 1254432.SCE1572_19660 7.2e-20 104.4 Deltaproteobacteria Bacteria 1PFYH@1224,2WWM6@28221,431GJ@68525,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T12.39_00491 450851.PHZ_c0607 4.1e-135 488.0 Caulobacterales nylB Bacteria 1P3SQ@1224,2KGKC@204458,2TTI5@28211,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T12.39_00492 366602.Caul_2176 8.6e-205 719.9 Caulobacterales Bacteria 1MUQH@1224,2KGKD@204458,2TRG4@28211,COG2072@1,COG2072@2 NA|NA|NA C Flavin-binding monooxygenase-like MAG.T12.39_00493 1537715.JQFJ01000002_gene2187 1e-285 989.6 Sphingomonadales ko:K07263 ko00000,ko01000,ko01002 Bacteria 1MVST@1224,2K05M@204457,2TRFB@28211,COG0612@1,COG0612@2 NA|NA|NA S Peptidase, M16 MAG.T12.39_00494 1144307.PMI04_01214 2.5e-65 255.4 Sphingomonadales tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Bacteria 1RCXZ@1224,2K1U9@204457,2U74E@28211,COG2755@1,COG2755@2 NA|NA|NA E COG2755 Lysophospholipase L1 and related esterases MAG.T12.39_00495 452662.SJA_C2-00770 6.9e-87 327.0 Sphingomonadales ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MXG9@1224,2JZZV@204457,2TS0J@28211,COG4181@1,COG4181@2 NA|NA|NA Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component MAG.T12.39_00496 627192.SLG_06440 5.8e-256 890.6 Sphingomonadales MA20_43810 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MU9R@1224,2K03T@204457,2TS8V@28211,COG3127@1,COG3127@2 NA|NA|NA Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component MAG.T12.39_00497 1173027.Mic7113_0724 7.1e-34 151.0 Oscillatoriales cmoA ko:K15256 ko00000,ko01000,ko03016 Bacteria 1G290@1117,1H9JI@1150,COG4976@1,COG4976@2 NA|NA|NA S Methyltransferase domain MAG.T12.39_00498 1510531.JQJJ01000010_gene2607 1.9e-55 222.6 Bradyrhizobiaceae glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 1PPTN@1224,2TW8M@28211,3JRC9@41294,COG0580@1,COG0580@2 NA|NA|NA G Belongs to the MIP aquaporin (TC 1.A.8) family MAG.T12.39_00499 450851.PHZ_c1438 1.3e-53 216.1 Caulobacterales arsC2 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1MWYQ@1224,2KGIA@204458,2TU1U@28211,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MAG.T12.39_00500 450851.PHZ_c1028 7.8e-34 149.8 Caulobacterales cadC 1.20.4.1 ko:K03741,ko:K03892 ko00000,ko01000,ko03000 Bacteria 1MZAU@1224,2KH38@204458,2U9NV@28211,COG0640@1,COG0640@2 NA|NA|NA K arsR family MAG.T12.39_00501 366602.Caul_2688 1e-81 310.5 Caulobacterales ko:K03543 M00701 ko00000,ko00002,ko02000 8.A.1.1 Bacteria 1MU7I@1224,2KFMT@204458,2TS39@28211,COG1566@1,COG1566@2 NA|NA|NA V PFAM secretion protein HlyD family protein MAG.T12.39_00502 366602.Caul_2690 1.1e-84 320.9 Caulobacterales Bacteria 1MUA8@1224,2KJTX@204458,2TVDE@28211,COG1538@1,COG1538@2 NA|NA|NA M Outer membrane efflux protein MAG.T12.39_00503 366602.Caul_2689 1e-130 473.8 Caulobacterales emrB ko:K03446 M00701 ko00000,ko00002,ko02000 2.A.1.3 Bacteria 1MU1I@1224,2KG3U@204458,2TVXT@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_00504 1449049.JONW01000010_gene3587 1e-166 593.2 Caulobacterales Bacteria 1MWYR@1224,2KIC4@204458,2TSXW@28211,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily MAG.T12.39_00505 1101190.ARWB01000001_gene1268 2.5e-38 166.0 Methylocystaceae str 2.7.1.72 ko:K04343 M00766 R02225 RC00002,RC00078 br01600,ko00000,ko00002,ko01000,ko01504 Bacteria 1MW4R@1224,2TU3X@28211,370G6@31993,COG3570@1,COG3570@2 NA|NA|NA V Aminoglycoside/hydroxyurea antibiotic resistance kinase MAG.T12.39_00507 228405.HNE_1350 3.8e-93 348.2 Alphaproteobacteria Bacteria 1NQ1W@1224,2UHA6@28211,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T12.39_00508 450851.PHZ_c2118 3.2e-53 215.3 Caulobacterales 1.3.8.7,2.3.1.9 ko:K00249,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00410,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko03320,map00071,map00072,map00280,map00310,map00362,map00380,map00410,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map03320 M00013,M00036,M00087,M00088,M00095,M00373,M00374,M00375 R00238,R00924,R01175,R01177,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00004,RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1NQAE@1224,2KH9Y@204458,2U0TJ@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain MAG.T12.39_00509 450851.PHZ_c2119 2.6e-163 581.6 Caulobacterales 1.3.8.6,1.3.8.7 ko:K00249,ko:K00252 ko00071,ko00280,ko00310,ko00362,ko00380,ko00410,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00310,map00362,map00380,map00410,map00640,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00032,M00036,M00087 R00924,R01175,R01279,R02487,R02488,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R10074 RC00052,RC00068,RC00076,RC00095,RC00148,RC00156,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0F@1224,2KFC2@204458,2TR9I@28211,COG1960@1,COG1960@2 NA|NA|NA C Acyl-CoA dehydrogenase, middle domain MAG.T12.39_00510 314225.ELI_09710 2.4e-23 115.2 Sphingomonadales Bacteria 1N0W7@1224,2K5XY@204457,2UC83@28211,COG3791@1,COG3791@2 NA|NA|NA S Glutathione-dependent formaldehyde-activating enzyme MAG.T12.39_00511 1282876.BAOK01000001_gene1692 4.5e-96 357.8 Alphaproteobacteria Bacteria 1R8E6@1224,2UPRX@28211,COG4221@1,COG4221@2 NA|NA|NA S KR domain MAG.T12.39_00512 1282876.BAOK01000001_gene1688 8.1e-89 333.6 Alphaproteobacteria Bacteria 1R623@1224,2U5F0@28211,COG1024@1,COG1024@2 NA|NA|NA I enoyl-CoA hydratase MAG.T12.39_00513 1210884.HG799466_gene12519 4.2e-40 172.2 Planctomycetes besA ko:K07017 ko00000 Bacteria 2J320@203682,COG2819@1,COG2819@2 NA|NA|NA S Putative esterase MAG.T12.39_00514 1230476.C207_01591 1.6e-165 589.0 Bradyrhizobiaceae Bacteria 1MY4M@1224,2DB8I@1,2U2A8@28211,2Z7RY@2,3JTM4@41294 NA|NA|NA MAG.T12.39_00515 579138.Zymop_1025 9.2e-10 70.1 Sphingomonadales ko:K16260 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1PUKP@1224,2KB0J@204457,2V113@28211,COG3832@1,COG3832@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport MAG.T12.39_00516 685778.AORL01000023_gene2104 2.1e-103 382.1 Sphingomonadales ygiD 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 Bacteria 1MXJZ@1224,2K0K2@204457,2TRJT@28211,COG3384@1,COG3384@2 NA|NA|NA S dioxygenase MAG.T12.39_00517 1282876.BAOK01000001_gene2087 6.1e-23 115.2 Alphaproteobacteria Bacteria 1R6GW@1224,28M2T@1,2U25T@28211,2ZAH6@2 NA|NA|NA MAG.T12.39_00518 366602.Caul_2061 2.3e-84 318.5 Caulobacterales frnE Bacteria 1NXUB@1224,2KK1S@204458,2U1PN@28211,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain MAG.T12.39_00519 521674.Plim_1562 8.9e-53 214.2 Planctomycetes ko:K06889 ko00000 Bacteria 2IXED@203682,COG1506@1,COG1506@2 NA|NA|NA E alpha/beta hydrolase fold MAG.T12.39_00521 743721.Psesu_2019 6e-10 70.9 Proteobacteria Bacteria 1NM6B@1224,2EU5E@1,33MN2@2 NA|NA|NA MAG.T12.39_00522 366602.Caul_0430 1.8e-140 506.1 Caulobacterales ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2KJSU@204458,2TVI8@28211,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein MAG.T12.39_00524 450851.PHZ_c0451 4.7e-65 255.0 Alphaproteobacteria pfkB 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVNW@1224,2U1H0@28211,COG1105@1,COG1105@2 NA|NA|NA H belongs to the carbohydrate kinase PfkB family MAG.T12.39_00525 89187.ISM_01665 5.3e-08 64.3 Roseovarius Bacteria 1RIEJ@1224,2U7UE@28211,46RZC@74030,COG5622@1,COG5622@2 NA|NA|NA N Protein required for attachment to host cells MAG.T12.39_00527 450851.PHZ_c2800 6.5e-11 73.6 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T12.39_00528 450851.PHZ_c2796 8.6e-189 666.8 Caulobacterales ko:K07576,ko:K07577 ko00000 Bacteria 1MUDD@1224,2KF2N@204458,2TVFM@28211,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain MAG.T12.39_00529 450851.PHZ_c2798 2.6e-54 218.8 Caulobacterales fixK ko:K01420,ko:K15861 ko02020,map02020 ko00000,ko00001,ko03000 Bacteria 1MVGE@1224,2KGTB@204458,2U36S@28211,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein MAG.T12.39_00530 450851.PHZ_c2799 7.9e-53 214.2 Caulobacterales Bacteria 1MWHD@1224,2KIW2@204458,2U0GR@28211,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family MAG.T12.39_00531 450851.PHZ_c2803 1.4e-145 523.1 Caulobacterales fixL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14986 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1RCM9@1224,2KG47@204458,2TR8X@28211,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T12.39_00532 450851.PHZ_c2804 4.2e-51 208.0 Caulobacterales ko:K14987 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko02022 Bacteria 1N6WR@1224,2KGU6@204458,2TUND@28211,COG4566@1,COG4566@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T12.39_00533 450851.PHZ_c2805 2.7e-27 128.3 Caulobacterales Bacteria 1MZ7R@1224,2KJQQ@204458,2UBUU@28211,COG4566@1,COG4566@2 NA|NA|NA T cheY-homologous receiver domain MAG.T12.39_00534 1449049.JONW01000006_gene2758 4.1e-99 367.9 Caulobacterales 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1MU6N@1224,2KF2Q@204458,2TR90@28211,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T12.39_00535 450851.PHZ_c2915 5.7e-47 194.1 Caulobacterales Bacteria 1MYIE@1224,2KK98@204458,2UAH0@28211,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeats MAG.T12.39_00536 450851.PHZ_c2920 1.6e-94 352.8 Caulobacterales Bacteria 1MZXM@1224,2KJ08@204458,2TSZM@28211,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T12.39_00537 1280949.HAD_04455 7.5e-146 523.5 Hyphomonadaceae tas GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 1.1.1.91 ko:K05882 ko00000,ko01000 Bacteria 1MV2Y@1224,2TSKV@28211,43X72@69657,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase MAG.T12.39_00538 311403.Arad_8339 1.1e-178 632.9 Rhizobiaceae bioA2 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 Bacteria 1MU2N@1224,2TQND@28211,4B7KK@82115,COG0161@1,COG0161@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T12.39_00539 450851.PHZ_c2652 2.8e-126 458.4 Caulobacterales Bacteria 1NFSV@1224,2KFQK@204458,2TSMV@28211,COG0500@1,COG0640@1,COG0640@2,COG2226@2 NA|NA|NA KQ regulatory protein, arsR MAG.T12.39_00540 450851.PHZ_c2651 5.9e-142 510.4 Caulobacterales metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 1MUC9@1224,2KFWD@204458,2TQZA@28211,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase MAG.T12.39_00541 69395.JQLZ01000001_gene2992 4.9e-90 337.8 Caulobacterales 3.5.2.6 ko:K17837 ko01501,map01501 R06363 RC01499 ko00000,ko00001,ko01000 Bacteria 1P5NJ@1224,2KGA9@204458,2TRXW@28211,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_00542 450851.PHZ_c2650 2.6e-173 614.8 Caulobacterales metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 Bacteria 1NPFY@1224,2KF2K@204458,2UJRS@28211,COG0646@1,COG0646@2 NA|NA|NA H PFAM homocysteine S-methyltransferase MAG.T12.39_00543 450851.PHZ_c2649 0.0 1372.8 Caulobacterales metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV6G@1224,2KFI4@204458,2TQTG@28211,COG1410@1,COG1410@2 NA|NA|NA H Vitamin B12 dependent methionine synthase activation MAG.T12.39_00544 1254432.SCE1572_27725 1e-48 201.1 Myxococcales Bacteria 1R3YS@1224,2X5HF@28221,2YVY1@29,43B23@68525,COG0477@1,COG2814@2 NA|NA|NA EGP Transmembrane secretion effector MAG.T12.39_00545 1121124.JNIX01000015_gene2003 2.1e-291 1007.7 Caulobacterales yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 ko00000,ko01000 Bacteria 1MU37@1224,2KF1Z@204458,2TS7G@28211,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T12.39_00546 666685.R2APBS1_2361 4.3e-79 301.2 Xanthomonadales ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MU45@1224,1RR3R@1236,1X57K@135614,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T12.39_00547 991905.SL003B_1030 7.6e-154 551.2 Alphaproteobacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MW6D@1224,2TTJZ@28211,COG0577@1,COG0577@2 NA|NA|NA V COG0577 ABC-type antimicrobial peptide transport system permease component MAG.T12.39_00548 279238.Saro_3585 2.3e-66 259.6 Sphingomonadales ko:K02005 ko00000 Bacteria 1Q10W@1224,2K9U3@204457,2TSC8@28211,COG0845@1,COG0845@2 NA|NA|NA M HlyD family secretion protein MAG.T12.39_00549 450851.PHZ_c0650 4.5e-231 807.7 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1NR6X@1224,2KFAY@204458,2UQQM@28211,COG4774@1,COG4774@2 NA|NA|NA P TonB-dependent receptor MAG.T12.39_00550 450851.PHZ_c1089 0.0 1467.2 Caulobacterales Bacteria 1MX3A@1224,2KG4I@204458,2TUU6@28211,COG0823@1,COG0823@2,COG1228@1,COG1228@2 NA|NA|NA QU Amidohydrolase family MAG.T12.39_00551 450851.PHZ_c2678 2.4e-199 701.4 Caulobacterales Bacteria 1MVJC@1224,2KG25@204458,2TTRD@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain MAG.T12.39_00552 450851.PHZ_c2679 1.2e-168 599.4 Caulobacterales Bacteria 1N05C@1224,2KG3G@204458,2TT9T@28211,COG1960@1,COG1960@2 NA|NA|NA I PFAM Acyl-CoA dehydrogenase MAG.T12.39_00553 59538.XP_005973479.1 0.0 1389.4 Cetartiodactyla Mammalia 38BX5@33154,3BDDJ@33208,3CUM1@33213,3J22W@40674,481XS@7711,48Z1G@7742,4J8KK@91561,COG0525@1,KOG0432@2759 NA|NA|NA J valine--tRNA MAG.T12.39_00554 190650.CC_1048 8.2e-119 434.5 Caulobacterales Bacteria 1MUJ3@1224,2KFCI@204458,2TUZZ@28211,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase MAG.T12.39_00555 450851.PHZ_c1343 3.2e-23 115.2 Caulobacterales fimV ko:K08086,ko:K09991 ko00000 Bacteria 1MX61@1224,2KGXT@204458,2TSG8@28211,COG3827@1,COG3827@2 NA|NA|NA S Protein of unknown function (DUF2497) MAG.T12.39_00556 450851.PHZ_c1342 2.1e-133 482.6 Caulobacterales bepC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1MWCJ@1224,2KFQU@204458,2TR3S@28211,COG1538@1,COG1538@2 NA|NA|NA MU type I secretion outer membrane protein, TolC family MAG.T12.39_00557 1292034.OR37_02491 1.5e-55 222.6 Caulobacterales 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1RD6S@1224,2KGUJ@204458,2U704@28211,COG2518@1,COG2518@2 NA|NA|NA O O-methyltransferase MAG.T12.39_00559 69395.JQLZ01000001_gene3321 4e-84 318.5 Caulobacterales Bacteria 1R97X@1224,28NB7@1,2KJXZ@204458,2U16I@28211,2ZBEQ@2 NA|NA|NA MAG.T12.39_00560 69395.JQLZ01000001_gene3321 1.7e-111 409.5 Caulobacterales Bacteria 1R97X@1224,28NB7@1,2KJXZ@204458,2U16I@28211,2ZBEQ@2 NA|NA|NA MAG.T12.39_00561 1266925.JHVX01000002_gene871 9.3e-206 723.0 Nitrosomonadales yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 Bacteria 1MU7B@1224,2VKQG@28216,371QI@32003,COG0069@1,COG0069@2 NA|NA|NA E Belongs to the glutamate synthase family MAG.T12.39_00562 652103.Rpdx1_0595 2.2e-74 285.8 Bradyrhizobiaceae Bacteria 1R9XW@1224,2U6IT@28211,3K3B6@41294,COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity MAG.T12.39_00563 450851.PHZ_c2065 5.6e-244 850.1 Caulobacterales 6.2.1.42 ko:K00666,ko:K18688 ko00000,ko01000,ko01004 Bacteria 1MVJ1@1224,2KIBE@204458,2TUQ9@28211,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_00564 190650.CC_0441 9.6e-13 80.1 Caulobacterales Bacteria 1NMHF@1224,2EJN1@1,2KHFU@204458,2UMJ4@28211,33DCY@2 NA|NA|NA MAG.T12.39_00565 366602.Caul_4312 1e-51 209.9 Caulobacterales 2.7.13.3 ko:K02487,ko:K03407,ko:K06596 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1RHY1@1224,2KGPW@204458,2UATB@28211,COG0784@1,COG0784@2 NA|NA|NA T Response regulator receiver MAG.T12.39_00566 509190.Cseg_3523 1.5e-135 489.6 Caulobacterales Bacteria 1NYRF@1224,2KFIU@204458,2U0BV@28211,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T12.39_00567 450851.PHZ_c2020 7.4e-169 600.1 Caulobacterales MA20_04655 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVJC@1224,2KFKM@204458,2TQRA@28211,COG1960@1,COG1960@2 NA|NA|NA C Acyl-CoA dehydrogenase, middle domain MAG.T12.39_00568 450851.PHZ_c0933 1.3e-242 845.9 Caulobacterales cckA 2.7.13.3 ko:K13587 ko02020,ko04112,map02020,map04112 M00512 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1RCM9@1224,2KF0Z@204458,2TQQ9@28211,COG0784@1,COG0784@2,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T12.39_00569 450851.PHZ_c0932 1.5e-99 369.8 Caulobacterales flhB ko:K02401,ko:K13820 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1MUWI@1224,2KFHV@204458,2TS13@28211,COG1377@1,COG1377@2 NA|NA|NA N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin MAG.T12.39_00570 450851.PHZ_c0931 5.4e-64 251.1 Caulobacterales fliR ko:K02421,ko:K03228,ko:K13820 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 1NIF4@1224,2KFQH@204458,2TTHN@28211,COG1684@1,COG1684@2 NA|NA|NA N Role in flagellar biosynthesis MAG.T12.39_00571 450851.PHZ_c0930 5.8e-26 123.2 Caulobacterales fliQ ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1N73W@1224,2KH0I@204458,2UBX6@28211,COG1987@1,COG1987@2 NA|NA|NA N Role in flagellar biosynthesis MAG.T12.39_00572 190650.CC_0955 6.8e-18 96.7 Caulobacterales fliE ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1PM5K@1224,2KH6Y@204458,2UZT5@28211,COG1677@1,COG1677@2 NA|NA|NA N Flagellar hook-basal body complex protein FliE MAG.T12.39_00573 509190.Cseg_3340 2.3e-48 198.4 Caulobacterales flgC GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1RHI3@1224,2KGQM@204458,2U94I@28211,COG1558@1,COG1558@2 NA|NA|NA N Belongs to the flagella basal body rod proteins family MAG.T12.39_00574 1292034.OR37_02602 2.3e-30 138.7 Caulobacterales flgB ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1N1G1@1224,2KH1U@204458,2UCJ4@28211,COG1815@1,COG1815@2 NA|NA|NA N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body MAG.T12.39_00575 450851.PHZ_c0923 9.4e-19 99.4 Caulobacterales fliO ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1NBFG@1224,2KH76@204458,2UDYE@28211,COG3190@1,COG3190@2 NA|NA|NA N Flagellar biosynthesis protein, FliO MAG.T12.39_00576 190650.CC_0951 2.1e-98 365.5 Caulobacterales fliP ko:K02419,ko:K03226 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 1MVBU@1224,2KFGQ@204458,2TT93@28211,COG1338@1,COG1338@2 NA|NA|NA N Plays a role in the flagellum-specific transport system MAG.T12.39_00577 450851.PHZ_c0921 0.0 1098.6 Caulobacterales Bacteria 1N09H@1224,2KF36@204458,2TSKT@28211,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T12.39_00578 450851.PHZ_c0920 1.2e-64 253.4 Caulobacterales MA20_08460 Bacteria 1RKF6@1224,2KGJB@204458,2TRR1@28211,COG3334@1,COG3334@2 NA|NA|NA S PFAM MgtE intracellular MAG.T12.39_00579 450851.PHZ_c0919 5e-21 107.8 Caulobacterales Bacteria 1NC36@1224,2EBS9@1,2KH7N@204458,2UGE1@28211,335S3@2 NA|NA|NA MAG.T12.39_00580 1449049.JONW01000011_gene2235 1.1e-158 566.2 Caulobacterales fliM ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 Bacteria 1MX01@1224,2KFGT@204458,2TR4F@28211,COG1868@1,COG1868@2 NA|NA|NA N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation MAG.T12.39_00581 450851.PHZ_c0917 4.5e-37 161.4 Caulobacterales fliL ko:K02415 ko00000,ko02035 Bacteria 1RH5D@1224,2KGKM@204458,2U7QV@28211,COG1580@1,COG1580@2 NA|NA|NA N Controls the rotational direction of flagella during chemotaxis MAG.T12.39_00582 450851.PHZ_c0916 7.3e-76 290.4 Caulobacterales flgF ko:K02391,ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1PZ24@1224,2KGAM@204458,2U06G@28211,COG4786@1,COG4786@2 NA|NA|NA N Belongs to the flagella basal body rod proteins family MAG.T12.39_00583 450851.PHZ_c0915 3.7e-108 397.9 Caulobacterales flgG ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MVMA@1224,2KF6X@204458,2TRR4@28211,COG4786@1,COG4786@2 NA|NA|NA N flagellar basal-body rod protein FlgG MAG.T12.39_00584 366602.Caul_1430 1.7e-59 236.1 Caulobacterales flgA ko:K02279,ko:K02386 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Bacteria 1PM4C@1224,2KGV6@204458,2TRUS@28211,COG1261@1,COG1261@2 NA|NA|NA N flagella basal body P-ring formation protein FlgA MAG.T12.39_00585 69395.JQLZ01000001_gene2744 4.8e-70 271.2 Caulobacterales flgH ko:K02393 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1RDEY@1224,2KG65@204458,2TRHN@28211,COG2063@1,COG2063@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation MAG.T12.39_00586 450851.PHZ_c0912 1.2e-306 1058.5 Caulobacterales dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 Bacteria 1MUSJ@1224,2KG2J@204458,2TRDD@28211,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) MAG.T12.39_00587 450851.PHZ_c0911 1.2e-104 386.3 Caulobacterales ispA GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1MWNG@1224,2KF53@204458,2TR79@28211,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T12.39_00588 450851.PHZ_c0910 8.8e-25 119.4 Caulobacterales xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1PTYQ@1224,2KH8R@204458,2UFD6@28211,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T12.39_00589 450851.PHZ_c0906 3.1e-58 231.5 Caulobacterales paiA GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1RDH4@1224,2KJUI@204458,2VEYV@28211,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T12.39_00590 450851.PHZ_c0904 2.4e-191 674.9 Caulobacterales MA20_01305 ko:K09989 ko00000 Bacteria 1MUAJ@1224,2KG62@204458,2TS5P@28211,COG3825@1,COG3825@2 NA|NA|NA S VWA domain containing CoxE-like protein MAG.T12.39_00591 450851.PHZ_c0903 1.1e-73 283.1 Caulobacterales psrA Bacteria 1RDIM@1224,2KHV1@204458,2VEVK@28211,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T12.39_00592 450851.PHZ_c0896 4.3e-165 587.8 Alphaproteobacteria Bacteria 1QYNP@1224,2U1VX@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_00593 266834.SM_b20421 7e-110 404.1 Rhizobiaceae Bacteria 1MXB5@1224,2U26E@28211,4BCIN@82115,COG5433@1,COG5433@2 NA|NA|NA L DDE_Tnp_1-associated MAG.T12.39_00594 450851.PHZ_c2716 2.1e-62 245.0 Caulobacterales mucR Bacteria 1RGUW@1224,2KGKZ@204458,2U99M@28211,COG4957@1,COG4957@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00595 366602.Caul_1359 5.9e-48 197.2 Caulobacterales Bacteria 1MY9D@1224,2KGR9@204458,2U9P1@28211,COG5388@1,COG5388@2 NA|NA|NA S PAS domain MAG.T12.39_00596 1382303.JPOM01000001_gene420 1.1e-48 199.5 Caulobacterales sufE ko:K02426 ko00000 Bacteria 1RI8F@1224,2KGUP@204458,2U9A2@28211,COG2166@1,COG2166@2 NA|NA|NA S Fe-S metabolism associated MAG.T12.39_00597 450851.PHZ_c2712 8.5e-82 310.8 Caulobacterales Bacteria 1NRP8@1224,2KFCY@204458,2TSRP@28211,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T12.39_00598 509190.Cseg_3194 5.3e-55 221.5 Caulobacterales Bacteria 1N5FG@1224,2DZY3@1,2KH3D@204458,2UEDV@28211,32VMW@2 NA|NA|NA MAG.T12.39_00599 190650.CC_1065 4.9e-38 163.7 Caulobacterales MA20_15690 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1N1KU@1224,2KGTT@204458,2UCBQ@28211,COG5447@1,COG5447@2 NA|NA|NA S Protein of unknown function (DUF1491) MAG.T12.39_00600 69395.JQLZ01000002_gene1552 2e-19 102.1 Caulobacterales Bacteria 1NCFT@1224,2E4EG@1,2KH7B@204458,2UGWK@28211,32Z9Q@2 NA|NA|NA MAG.T12.39_00601 450851.PHZ_c2707 1.4e-242 845.5 Caulobacterales prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1MU7X@1224,2KF8G@204458,2TRP5@28211,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP MAG.T12.39_00602 450851.PHZ_c2301 1.8e-90 339.3 Caulobacterales rsmC 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1MXE9@1224,2KFQT@204458,2TSBA@28211,COG2813@1,COG2813@2 NA|NA|NA J methyltransferase small MAG.T12.39_00603 1292034.OR37_00287 4e-83 314.7 Caulobacterales rsuA 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1MU6M@1224,2KFME@204458,2TT86@28211,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T12.39_00604 450851.PHZ_c2706 1.5e-78 300.4 Caulobacterales Bacteria 1QVFY@1224,2KK77@204458,2TWEH@28211,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T12.39_00606 366602.Caul_4345 8.4e-26 123.2 Caulobacterales 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1Q1P4@1224,2KH3K@204458,2UF0J@28211,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin MAG.T12.39_00607 450851.PHZ_c2848 5.6e-71 274.2 Caulobacterales Bacteria 1MUUV@1224,2KF20@204458,2TR0A@28211,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM short-chain dehydrogenase reductase SDR MAG.T12.39_00608 450851.PHZ_c2847 4.2e-143 514.2 Alphaproteobacteria 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MVQM@1224,2U3TF@28211,COG3386@1,COG3386@2 NA|NA|NA G SMP-30/Gluconolaconase/LRE-like region MAG.T12.39_00609 450851.PHZ_c2846 4.8e-231 807.0 Caulobacterales aldh1 1.2.1.3,1.2.1.83 ko:K00128,ko:K19700 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00811 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R10105 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,2KG83@204458,2TQR1@28211,COG1012@1,COG1012@2 NA|NA|NA C belongs to the aldehyde dehydrogenase family MAG.T12.39_00610 59538.XP_005974713.1 9.1e-199 699.9 Cetartiodactyla Mammalia 3AIZB@33154,3BXNQ@33208,3DFMP@33213,3JP3T@40674,48SPA@7711,49P71@7742,4J1NF@91561,COG0318@1,KOG1176@2759 NA|NA|NA I 4-coumarate--CoA MAG.T12.39_00611 450851.PHZ_c2845 2e-100 372.5 Caulobacterales ko:K01066 ko00000,ko01000 Bacteria 1NEXK@1224,2KGT4@204458,2U5X1@28211,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T12.39_00612 1382303.JPOM01000001_gene2062 3.6e-118 431.8 Caulobacterales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 1MW15@1224,2KFF6@204458,2TSI5@28211,COG3004@1,COG3004@2 NA|NA|NA P ) H( ) antiporter that extrudes sodium in exchange for external protons MAG.T12.39_00613 450851.PHZ_c2841 6.9e-182 643.7 Caulobacterales Bacteria 1MVK3@1224,2KF22@204458,2TT84@28211,COG0397@1,COG0397@2 NA|NA|NA S Uncharacterized ACR, YdiU/UPF0061 family MAG.T12.39_00614 1229204.AMYY01000020_gene483 1.7e-85 322.8 Alphaproteobacteria Bacteria 1RCED@1224,2U66Q@28211,COG0697@1,COG0697@2 NA|NA|NA EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily MAG.T12.39_00615 450851.PHZ_c2840 2.9e-72 278.5 Caulobacterales gluQ 6.1.1.17 ko:K01885,ko:K01894 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 1MUN7@1224,2KF9H@204458,2TR2V@28211,COG0008@1,COG0008@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T12.39_00616 366602.Caul_3204 4.6e-61 241.1 Caulobacterales Bacteria 1MUUY@1224,2KHBU@204458,2TUIH@28211,COG1309@1,COG1309@2 NA|NA|NA K WHG domain MAG.T12.39_00619 450851.PHZ_c2836 1.1e-74 286.2 Caulobacterales coq7 ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 Bacteria 1RAK4@1224,2KGD3@204458,2U85I@28211,COG2941@1,COG2941@2 NA|NA|NA H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol MAG.T12.39_00620 190650.CC_2196 3e-45 188.3 Caulobacterales dsbB ko:K03611 ko00000,ko03110 5.A.2.1 Bacteria 1N89I@1224,2KH18@204458,2UE1Z@28211,COG1495@1,COG1495@2 NA|NA|NA O bond formation protein DsbB MAG.T12.39_00621 450851.PHZ_c2834 8.7e-67 260.0 Caulobacterales MA20_20865 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1MWED@1224,2KGMV@204458,2U78A@28211,COG1238@1,COG1238@2 NA|NA|NA S SNARE associated Golgi protein MAG.T12.39_00622 509190.Cseg_3670 1.3e-233 815.8 Caulobacterales feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 1MUZC@1224,2KF4N@204458,2TQSU@28211,COG0370@1,COG0370@2 NA|NA|NA P Ferrous iron transport protein B MAG.T12.39_00623 450851.PHZ_c2825 2.1e-19 101.7 Caulobacterales feoA ko:K04758 ko00000,ko02000 Bacteria 1N8DT@1224,2KH9B@204458,2UFJ3@28211,COG1918@1,COG1918@2 NA|NA|NA P FeoA MAG.T12.39_00625 69395.JQLZ01000001_gene3471 1.9e-173 615.5 Caulobacterales dctA ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 2.A.23.1.3,2.A.23.1.6,2.A.23.1.7 Bacteria 1MU0Q@1224,2KG5U@204458,2TRET@28211,COG1301@1,COG1301@2 NA|NA|NA C Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate MAG.T12.39_00626 1174684.EBMC1_14645 7.1e-67 260.4 Sphingomonadales 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1Q05U@1224,2KD17@204457,2TTDK@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain MAG.T12.39_00627 1382303.JPOM01000001_gene43 2.1e-101 375.6 Alphaproteobacteria 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1PK10@1224,2TS4M@28211,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T12.39_00628 1120983.KB894571_gene2022 3.1e-24 119.0 Rhodobiaceae ko:K06076 ko00000,ko02000 1.B.9 Bacteria 1JQBC@119043,1PT37@1224,2VCS1@28211,COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transport protein MAG.T12.39_00629 69395.JQLZ01000001_gene3468 3.4e-78 297.7 Caulobacterales carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K07736 ko00000,ko03000 Bacteria 1MWI2@1224,2KFC7@204458,2TTVP@28211,COG1329@1,COG1329@2 NA|NA|NA K CarD family MAG.T12.39_00630 1292034.OR37_01003 6.7e-59 233.0 Caulobacterales fdxA ko:K05524 ko00000 Bacteria 1RH5I@1224,2KGH9@204458,2U98K@28211,COG1146@1,COG1146@2 NA|NA|NA C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions MAG.T12.39_00631 420324.KI912060_gene5838 5.6e-285 986.9 Methylobacteriaceae penA 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 1JR0G@119045,1MVMH@1224,2TS4D@28211,COG2366@1,COG2366@2 NA|NA|NA S PFAM peptidase S45 penicillin amidase MAG.T12.39_00632 450851.PHZ_c0709 5e-31 140.2 Caulobacterales hslR ko:K04762 ko00000,ko03110 Bacteria 1PBTE@1224,2KH55@204458,2VAP7@28211,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein MAG.T12.39_00633 450851.PHZ_c0710 4.1e-294 1017.3 Caulobacterales mgpS 3.6.4.13 ko:K17675 ko00000,ko01000,ko03029 Bacteria 1MVD6@1224,2KEXN@204458,2TR7N@28211,COG4581@1,COG4581@2 NA|NA|NA L Helicase MAG.T12.39_00634 1292034.OR37_01896 5.5e-29 133.3 Caulobacterales rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ57@1224,2KGZP@204458,2UBQU@28211,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family MAG.T12.39_00635 402881.Plav_0089 2.6e-144 518.5 Rhodobiaceae 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1JPNM@119043,1MUK4@1224,2V8RZ@28211,COG1062@1,COG1062@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain MAG.T12.39_00636 1449049.JONW01000005_gene1261 2.2e-62 246.1 Caulobacterales Bacteria 1N7Y1@1224,2KH6A@204458,2TTZW@28211,COG4246@1,COG4246@2 NA|NA|NA S Esterase-like activity of phytase MAG.T12.39_00637 450851.PHZ_c0724 2.4e-281 974.5 Caulobacterales cobT 3.4.17.14,6.6.1.2 ko:K07114,ko:K07260,ko:K09883 ko00550,ko00860,ko01100,ko01502,ko02020,map00550,map00860,map01100,map01502,map02020 M00651 R05227 RC02000 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1MX11@1224,2KFC6@204458,2TS4N@28211,COG4547@1,COG4547@2 NA|NA|NA H cobalt chelatase MAG.T12.39_00638 450851.PHZ_c0726 2.2e-117 429.1 Caulobacterales pla GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 Bacteria 1QDFI@1224,2KIAB@204458,2U244@28211,COG2267@1,COG2267@2 NA|NA|NA I Protein of unknown function (DUF3089) MAG.T12.39_00639 450851.PHZ_c0727 1.1e-165 589.3 Caulobacterales cobS 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 R05227 RC02000 ko00000,ko00001,ko01000 Bacteria 1MXIW@1224,2KF2M@204458,2TS1Z@28211,COG0714@1,COG0714@2 NA|NA|NA S TIGRFAM cobalt chelatase, pCobS small subunit MAG.T12.39_00640 450851.PHZ_c0729 7.5e-123 446.8 Caulobacterales 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 R05320 RC01331 ko00000,ko00001,ko01000 Bacteria 1MV5K@1224,2KIUC@204458,2TQTZ@28211,COG2175@1,COG2175@2 NA|NA|NA Q PFAM Taurine catabolism dioxygenase TauD TfdA MAG.T12.39_00641 983920.Y88_3100 8.3e-164 584.7 Proteobacteria Bacteria 1MUME@1224,COG2982@1,COG2982@2 NA|NA|NA M Domain of Unknown Function (DUF748) MAG.T12.39_00642 450851.PHZ_c0736 1.7e-79 302.4 Caulobacterales ko:K04562 ko00000,ko02035 Bacteria 1MXTG@1224,2KG93@204458,2TRZH@28211,COG2214@1,COG2214@2 NA|NA|NA O PFAM heat shock protein DnaJ domain protein MAG.T12.39_00643 450851.PHZ_c0737 1.9e-27 128.3 Caulobacterales bolA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576 ko:K05527,ko:K22066 ko00000,ko03000,ko03029 Bacteria 1MZG5@1224,2KH96@204458,2UF6U@28211,COG0271@1,COG0271@2 NA|NA|NA T Belongs to the BolA IbaG family MAG.T12.39_00644 450851.PHZ_c0738 1.4e-68 265.8 Caulobacterales 1.3.99.16 ko:K07302,ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY3F@1224,2KGXM@204458,2TRGH@28211,COG2080@1,COG2080@2 NA|NA|NA C [2Fe-2S] binding domain MAG.T12.39_00645 450851.PHZ_c0739 4.3e-95 354.8 Caulobacterales yagS GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVJS@1224,2KGB9@204458,2TRAR@28211,COG1319@1,COG1319@2 NA|NA|NA C CO dehydrogenase flavoprotein C-terminal domain MAG.T12.39_00646 450851.PHZ_c0740 4.5e-308 1063.5 Caulobacterales yagR GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUEA@1224,2KK0P@204458,2TRFN@28211,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MAG.T12.39_00647 1449049.JONW01000002_gene2424 1.7e-171 609.0 Caulobacterales yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 1NZ99@1224,2KG4J@204458,2TVZH@28211,COG4536@1,COG4536@2 NA|NA|NA P CBS domain MAG.T12.39_00648 450851.PHZ_c0743 1.6e-149 535.8 Caulobacterales aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iIT341.HP0283,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 Bacteria 1MUBK@1224,2KFPW@204458,2TRDA@28211,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) MAG.T12.39_00649 450851.PHZ_c0744 1.8e-66 258.8 Caulobacterales aroK 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUFJ@1224,2KGME@204458,2U76C@28211,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate MAG.T12.39_00650 450851.PHZ_c0746 4.5e-121 441.0 Caulobacterales xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1MVNF@1224,2KFAZ@204458,2TRAA@28211,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily MAG.T12.39_00651 450851.PHZ_c0748 3e-136 491.5 Caulobacterales accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1MURN@1224,2KFYI@204458,2TR6V@28211,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA MAG.T12.39_00652 450851.PHZ_c0749 1.6e-153 548.9 Caulobacterales MA20_15180 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MWPC@1224,2KFXW@204458,2TQRT@28211,COG2070@1,COG2070@2 NA|NA|NA S PFAM 2-nitropropane dioxygenase NPD MAG.T12.39_00653 450851.PHZ_c0751 5.5e-125 454.1 Caulobacterales ltaE 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 1MWCR@1224,2KFPF@204458,2TSUA@28211,COG2008@1,COG2008@2 NA|NA|NA E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde MAG.T12.39_00654 450851.PHZ_c0752 6.6e-191 673.3 Caulobacterales 3.3.2.9 ko:K01253,ko:K21159 ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204 R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443 RC01447,RC01728,RC01764,RC02528 ko00000,ko00001,ko01000,ko01002 Bacteria 1MWVN@1224,2KFMH@204458,2TQVB@28211,COG0596@1,COG0596@2 NA|NA|NA S Epoxide hydrolase N terminus MAG.T12.39_00655 450851.PHZ_c0753 3.6e-44 184.9 Caulobacterales Bacteria 1RHEM@1224,2KIKR@204458,2UDIZ@28211,COG1309@1,COG1309@2 NA|NA|NA K WHG domain MAG.T12.39_00656 450851.PHZ_c0754 2.1e-191 675.2 Caulobacterales MA20_08640 ko:K11159 ko00000 Bacteria 1MY1X@1224,2KG2S@204458,2TS7A@28211,COG3670@1,COG3670@2 NA|NA|NA Q dioxygenase MAG.T12.39_00657 450851.PHZ_c0949 4.9e-109 401.4 Caulobacterales GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 1Q80V@1224,2KFYD@204458,2U155@28211,COG0121@1,COG0121@2 NA|NA|NA I Phosphoinositide phospholipase C, Ca2+-dependent MAG.T12.39_00658 1123269.NX02_01105 1.8e-09 69.7 Sphingomonadales ko:K07052 ko00000 Bacteria 1MYYZ@1224,2KCH2@204457,2UM8W@28211,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T12.39_00659 1333998.M2A_1735 1.5e-97 363.2 unclassified Alphaproteobacteria nagX 1.14.13.1 ko:K00480 ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220 R00818,R05632,R06915,R06936,R06939 RC00389 ko00000,ko00001,ko01000 Bacteria 1MWWT@1224,2TRZP@28211,4BQRX@82117,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T12.39_00660 1304883.KI912532_gene2180 3.9e-68 264.2 Rhodocyclales dps ko:K04047 ko00000,ko03036 Bacteria 1RAC5@1224,2KW76@206389,2VHJI@28216,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family MAG.T12.39_00661 1244869.H261_06651 2.6e-58 232.3 Alphaproteobacteria 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 ko:K00543,ko:K16130,ko:K18896,ko:K18897,ko:K21515 ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100 M00037 R03130,R04905,R10060,R10061 RC00003,RC00392,RC03038,RC03040 ko00000,ko00001,ko00002,ko01000,ko01008,ko03009 Bacteria 1N6WZ@1224,2TZQD@28211,COG0457@1,COG0457@2,COG2890@1,COG2890@2 NA|NA|NA J protein-(glutamine-N5) methyltransferase activity MAG.T12.39_00662 228405.HNE_3132 1.2e-104 386.0 Hyphomonadaceae Bacteria 1MWMJ@1224,2TU8B@28211,43WQK@69657,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase MAG.T12.39_00663 688245.CtCNB1_1922 1.3e-211 743.0 Comamonadaceae 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2VIFW@28216,4AB9I@80864,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T12.39_00664 450851.PHZ_c3127 2e-183 649.8 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MU9K@1224,2KEZ7@204458,2TS65@28211,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T12.39_00665 1280953.HOC_13099 7.5e-107 394.4 Hyphomonadaceae ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2TVI8@28211,43XT1@69657,COG2211@1,COG2211@2 NA|NA|NA G COG2211 Na melibiose symporter and related transporters MAG.T12.39_00666 1380355.JNIJ01000011_gene862 7.9e-166 590.1 Bradyrhizobiaceae Bacteria 1MURK@1224,2U10C@28211,3JR02@41294,COG4948@1,COG4948@2 NA|NA|NA M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAG.T12.39_00667 246200.SPOA0386 8.2e-158 563.9 Ruegeria 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV19@1224,2TQKQ@28211,4NBWG@97050,COG2303@1,COG2303@2 NA|NA|NA C Belongs to the GMC oxidoreductase family MAG.T12.39_00668 402881.Plav_0829 3.9e-79 301.6 Alphaproteobacteria 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 R05320 RC01331 ko00000,ko00001,ko01000 Bacteria 1MV5K@1224,2U38D@28211,COG2175@1,COG2175@2 NA|NA|NA Q taurine catabolism dioxygenase MAG.T12.39_00669 1157708.KB907451_gene4601 1e-36 161.0 Betaproteobacteria Bacteria 1P4M5@1224,2VY3J@28216,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T12.39_00670 745014.OMB55_00020560 1.4e-143 516.2 Gammaproteobacteria Bacteria 1NX52@1224,1RYVM@1236,COG1073@1,COG1073@2 NA|NA|NA S Alpha beta hydrolase MAG.T12.39_00671 1313172.YM304_16990 1.6e-62 246.1 Actinobacteria ko:K08234 ko00000 Bacteria 2IEKM@201174,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T12.39_00672 1280944.HY17_10010 2.1e-214 751.5 Hyphomonadaceae MA20_06720 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVJC@1224,2TTRD@28211,43ZC5@69657,COG1960@1,COG1960@2 NA|NA|NA I COG1960 Acyl-CoA dehydrogenases MAG.T12.39_00673 1280954.HPO_03909 3.4e-155 554.7 Hyphomonadaceae MA20_06725 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1N05C@1224,2TT9T@28211,43Z8N@69657,COG1960@1,COG1960@2 NA|NA|NA I COG1960 Acyl-CoA dehydrogenases MAG.T12.39_00674 69395.JQLZ01000001_gene3187 2.3e-38 164.9 Caulobacterales Bacteria 1RJJB@1224,2B9KW@1,2KGS6@204458,2UAVD@28211,322Z5@2 NA|NA|NA MAG.T12.39_00675 1346791.M529_02785 5.7e-66 257.7 Sphingomonadales Bacteria 1MV9V@1224,2C1VC@1,2K4V3@204457,2U2N5@28211,2Z83Q@2 NA|NA|NA MAG.T12.39_00676 1525715.IX54_11820 1.3e-65 256.1 Paracoccus pfs 3.2.2.1,3.2.2.9 ko:K01239,ko:K01243 ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230 M00034,M00609 R00194,R01245,R01273,R01401,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko00002,ko01000 Bacteria 1R9VR@1224,2PVXV@265,2U5H0@28211,COG0775@1,COG0775@2 NA|NA|NA F Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine MAG.T12.39_00677 366602.Caul_2472 4.4e-31 140.6 Caulobacterales ko:K22042 ko00000,ko03000 Bacteria 1N72Q@1224,2KJ72@204458,2UFSY@28211,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T12.39_00678 366602.Caul_2473 0.0 1656.0 Caulobacterales Bacteria 1MU48@1224,2KFBP@204458,2TQT0@28211,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T12.39_00679 366602.Caul_2474 1e-94 353.6 Caulobacterales Bacteria 1MXU4@1224,2KF1U@204458,2TUXB@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T12.39_00680 366602.Caul_2475 1.7e-36 158.7 Caulobacterales ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 1N2R7@1224,2KH63@204458,2U9G7@28211,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T12.39_00681 366602.Caul_2477 1.3e-203 715.7 Caulobacterales sqr GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 1QSG6@1224,2KFZB@204458,2TUP1@28211,COG0446@1,COG0446@2 NA|NA|NA S FAD-dependent pyridine MAG.T12.39_00682 366602.Caul_2479 1.5e-18 98.2 Caulobacterales ygaP Bacteria 1N6NN@1224,2KHDC@204458,2UFC1@28211,32YCZ@2,COG0607@1 NA|NA|NA P Protein of unknown function (DUF2892) MAG.T12.39_00683 1280952.HJA_03066 1.1e-188 666.4 Hyphomonadaceae phrB GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K06876 ko00000 Bacteria 1MUHX@1224,2TQP6@28211,43WER@69657,COG3046@1,COG3046@2 NA|NA|NA S protein related to deoxyribodipyrimidine photolyase MAG.T12.39_00684 190650.CC_0185 1.6e-303 1048.5 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QTXJ@1224,2KI21@204458,2TWA4@28211,COG4773@1,COG4773@2 NA|NA|NA P TonB dependent receptor MAG.T12.39_00685 349163.Acry_2762 5.9e-73 280.8 Rhodospirillales Bacteria 1RAEZ@1224,2JRXC@204441,2U7DM@28211,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MAG.T12.39_00686 450851.PHZ_c2886 5.3e-46 190.7 Caulobacterales ko:K13643 ko00000,ko03000 Bacteria 1RDA4@1224,2KGZC@204458,2U9GW@28211,COG1959@1,COG1959@2 NA|NA|NA K Rrf2 family MAG.T12.39_00687 1121123.AUAO01000001_gene909 3.4e-98 364.8 Caulobacterales ytnM ko:K07090 ko00000 Bacteria 1PGTZ@1224,2KHJX@204458,2U5IZ@28211,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T12.39_00689 1245469.S58_50480 1.1e-137 496.1 Bradyrhizobiaceae yghU GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015036,GO:0016491,GO:0016667,GO:0055114 ko:K11209 ko00000,ko01000 Bacteria 1MUN3@1224,2TTDF@28211,3JTWQ@41294,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain MAG.T12.39_00690 402881.Plav_1623 3.3e-285 987.3 Alphaproteobacteria 1.14.13.22 ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko01000 Bacteria 1NSY9@1224,2TUSD@28211,COG2072@1,COG2072@2 NA|NA|NA P Flavoprotein involved in K transport MAG.T12.39_00691 247634.GPB2148_3483 9e-114 417.2 unclassified Gammaproteobacteria Bacteria 1JBEK@118884,1MVAA@1224,1S2VM@1236,COG1073@1,COG1073@2 NA|NA|NA S Secretory lipase family protein MAG.T12.39_00692 450851.PHZ_c0728 2.5e-43 181.4 Caulobacterales 3.3.2.8 ko:K10533 ko00903,map00903 R05784,R09387 RC01473,RC02519 ko00000,ko00001,ko01000 Bacteria 1RJ3T@1224,2KJQM@204458,2UAH6@28211,COG4308@1,COG4308@2 NA|NA|NA Q Limonene-1,2-epoxide hydrolase catalytic domain MAG.T12.39_00693 292.DM42_4463 2.1e-33 149.1 Bacteria ywlE 3.1.3.48,3.9.1.2,5.3.1.6 ko:K01104,ko:K01808,ko:K20201 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MAG.T12.39_00694 1217720.ALOX01000034_gene330 7.5e-273 946.4 Rhodospirillales glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVEV@1224,2JPK5@204441,2TS9R@28211,COG2225@1,COG2225@2 NA|NA|NA C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA MAG.T12.39_00695 452662.SJA_C1-28320 4e-190 671.0 Sphingomonadales ko:K07110,ko:K21686,ko:K22300 ko00000,ko03000 Bacteria 1MU50@1224,2K126@204457,2TRKE@28211,COG1396@1,COG1396@2,COG3800@1,COG3800@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00696 1123269.NX02_24125 1.8e-271 941.4 Sphingomonadales aceA 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWIF@1224,2K0CD@204457,2TU0Q@28211,COG2224@1,COG2224@2 NA|NA|NA C Isocitrate lyase MAG.T12.39_00697 190650.CC_2257 1.7e-103 382.5 Caulobacterales Bacteria 1NNHX@1224,2KGD8@204458,2U45K@28211,COG4798@1,COG4798@2 NA|NA|NA S methyltransferase MAG.T12.39_00698 314345.SPV1_07019 2.3e-50 205.7 Proteobacteria yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1REE7@1224,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain MAG.T12.39_00699 1121949.AQXT01000002_gene1266 1.8e-115 422.2 Hyphomonadaceae 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 iAF987.Gmet_2224 Bacteria 1MVQN@1224,2UNSV@28211,43ZQ0@69657,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase isomerase family protein MAG.T12.39_00700 1123504.JQKD01000053_gene4352 1.8e-29 135.2 Comamonadaceae ko:K07726 ko00000,ko03000 Bacteria 1N05Y@1224,2VSDE@28216,4AEHH@80864,COG2944@1,COG2944@2 NA|NA|NA K Helix-turn-helix MAG.T12.39_00701 1522072.IL54_0024 8.1e-15 86.7 Bacteria ko:K07075 ko00000 Bacteria COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 MAG.T12.39_00702 1187851.A33M_4043 2.3e-15 88.2 Alphaproteobacteria ko:K07075 ko00000 Bacteria 1N8UR@1224,2UFTP@28211,COG1669@1,COG1669@2 NA|NA|NA S DNA polymerase beta MAG.T12.39_00703 450851.PHZ_c3391 1e-65 256.9 Caulobacterales Bacteria 1MVRU@1224,2KH33@204458,2TRUD@28211,COG5473@1,COG5473@2 NA|NA|NA S Predicted integral membrane protein (DUF2189) MAG.T12.39_00704 1157708.KB907458_gene1720 0.0 1553.9 Betaproteobacteria Z012_07420 3.1.21.3,3.1.21.5 ko:K01153,ko:K01156 ko00000,ko01000,ko02048 Bacteria 1MVNN@1224,2VJP7@28216,COG0610@1,COG0610@2 NA|NA|NA V Type III restriction enzyme, res subunit MAG.T12.39_00705 760117.JN27_23865 0.0 1184.1 Oxalobacteraceae 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1PJW1@1224,2W9W8@28216,477UT@75682,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase MAG.T12.39_00706 1304275.C41B8_14335 0.0 1079.7 Gammaproteobacteria Bacteria 1MX6H@1224,1RNRZ@1236,COG0553@1,COG0553@2 NA|NA|NA K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair MAG.T12.39_00708 392499.Swit_3346 2.1e-07 61.2 Sphingomonadales Bacteria 1NGJ7@1224,2EM3U@1,2K70N@204457,2UM9K@28211,33ETB@2 NA|NA|NA MAG.T12.39_00710 228405.HNE_2412 1.2e-177 629.8 Alphaproteobacteria Bacteria 1MWWY@1224,2TR1E@28211,COG3653@1,COG3653@2 NA|NA|NA Q amidohydrolase MAG.T12.39_00711 450851.PHZ_c2806 5.4e-163 580.9 Caulobacterales hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 Bacteria 1MV1I@1224,2KFVX@204458,2TRKT@28211,COG0635@1,COG0635@2 NA|NA|NA H Belongs to the anaerobic coproporphyrinogen-III oxidase family MAG.T12.39_00712 190650.CC_3120 0.0 1464.1 Caulobacterales Bacteria 1MU48@1224,2KFUZ@204458,2TQT0@28211,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T12.39_00713 1449049.JONW01000005_gene1000 1.8e-94 352.8 Alphaproteobacteria ko:K18302 M00642 ko00000,ko00002,ko01504,ko02000 2.A.6.2,8.A.1 Bacteria 1R443@1224,2U9PM@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T12.39_00714 366602.Caul_3929 6.6e-55 220.7 Caulobacterales Bacteria 1N6R3@1224,2KK2D@204458,2UIAY@28211,COG1309@1,COG1309@2 NA|NA|NA K WHG domain MAG.T12.39_00715 402881.Plav_0559 1.2e-84 319.7 Alphaproteobacteria Bacteria 1R6PG@1224,2U54K@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_00716 502025.Hoch_5418 8.7e-114 417.5 Myxococcales Bacteria 1QE2X@1224,2AR28@1,2X35Y@28221,2YUEY@29,31GB8@2,43F2T@68525 NA|NA|NA MAG.T12.39_00717 502025.Hoch_5419 4.2e-27 128.3 Myxococcales Bacteria 1Q2I1@1224,2AIX2@1,2X3EX@28221,2YVRW@29,319EQ@2,4384W@68525 NA|NA|NA MAG.T12.39_00718 502025.Hoch_5420 8.6e-146 523.9 Myxococcales Bacteria 1Q1SS@1224,2AIN7@1,2X2NH@28221,2YU01@29,3194K@2,437FX@68525 NA|NA|NA MAG.T12.39_00719 1333998.M2A_2873 4.1e-09 68.6 Bacteria Bacteria 2DS98@1,33F2N@2 NA|NA|NA MAG.T12.39_00720 1502850.FG91_02806 3.6e-71 274.6 Sphingomonadales Bacteria 1MWCV@1224,2KANC@204457,2U6HU@28211,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T12.39_00721 1537715.JQFJ01000005_gene129 4e-92 344.4 Sphingomonadales Bacteria 1PMH5@1224,2K8H1@204457,2TVAY@28211,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T12.39_00722 450851.PHZ_c3077 4.7e-122 444.5 Alphaproteobacteria Bacteria 1RCPZ@1224,28NHI@1,2UKQP@28211,2ZBJA@2 NA|NA|NA MAG.T12.39_00723 1123377.AUIV01000003_gene1828 1.2e-40 172.9 Xanthomonadales Bacteria 1REB4@1224,1SBNU@1236,1XAPM@135614,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein MAG.T12.39_00724 1280944.HY17_05005 1.1e-13 82.4 Alphaproteobacteria Bacteria 1N6QZ@1224,2UGR1@28211,COG3369@1,COG3369@2 NA|NA|NA S Iron-binding zinc finger CDGSH type MAG.T12.39_00725 1174684.EBMC1_16159 3e-114 418.7 Sphingomonadales nylB Bacteria 1P3SQ@1224,2K1R1@204457,2TTI5@28211,COG1680@1,COG1680@2 NA|NA|NA V COG1680 Beta-lactamase class C and other penicillin binding proteins MAG.T12.39_00727 450851.PHZ_c2774 4.3e-132 478.0 Caulobacterales Bacteria 1MVJC@1224,2KFB8@204458,2TUVB@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM acyl-CoA dehydrogenase domain protein MAG.T12.39_00728 876269.ARWA01000001_gene2353 3.3e-20 105.1 Alphaproteobacteria Bacteria 1NC0H@1224,2DPZY@1,2UM0V@28211,3345E@2 NA|NA|NA MAG.T12.39_00729 450851.PHZ_c0568 2e-226 792.0 Caulobacterales MA20_06730 6.2.1.34 ko:K12508 ko00000,ko01000 Bacteria 1MUQZ@1224,2KFYA@204458,2TRV7@28211,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase MAG.T12.39_00730 450851.PHZ_c0567 1.2e-208 732.6 Caulobacterales 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX6Q@1224,2KG23@204458,2TR5N@28211,COG0028@1,COG0028@2 NA|NA|NA EH thiamine pyrophosphate protein TPP binding domain protein MAG.T12.39_00731 450851.PHZ_c0566 2.2e-121 442.6 Caulobacterales Bacteria 1RHBH@1224,2C0IQ@1,2KGPF@204458,2UB5X@28211,32R73@2 NA|NA|NA MAG.T12.39_00732 366602.Caul_0680 2.8e-143 515.0 Caulobacterales yqjP Bacteria 1MUXF@1224,2KFGU@204458,2TSYY@28211,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_00733 1449049.JONW01000006_gene3303 3.2e-57 228.0 Caulobacterales MA20_02285 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1QTZ4@1224,2KGK3@204458,2U7E4@28211,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T12.39_00734 450851.PHZ_c2881 5.9e-61 240.7 Alphaproteobacteria Bacteria 1MZAM@1224,2US5F@28211,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T12.39_00735 1280952.HJA_06562 1.4e-109 402.9 Hyphomonadaceae Bacteria 1MXNQ@1224,2TS6G@28211,43X6G@69657,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MAG.T12.39_00736 450851.PHZ_c2880 4.9e-155 554.3 Caulobacterales entS Bacteria 1QTX0@1224,2KK7G@204458,2TUM5@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_00738 450851.PHZ_c2879 2.1e-37 162.2 Caulobacterales MA20_06530 ko:K03824 ko00000,ko01000 Bacteria 1RD0C@1224,2KH8Q@204458,2U7AS@28211,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) family MAG.T12.39_00739 69395.JQLZ01000006_gene2218 2.5e-69 268.5 Caulobacterales MA20_44640 ko:K09986 ko00000 Bacteria 1RD5Q@1224,2KGGT@204458,2U7DA@28211,COG3816@1,COG3816@2 NA|NA|NA S Protein of unknown function (DUF1285) MAG.T12.39_00740 450851.PHZ_c2877 1.1e-65 256.5 Caulobacterales nudL Bacteria 1RD2C@1224,2KGKE@204458,2TV3Q@28211,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T12.39_00741 59538.XP_005976333.1 7.9e-129 467.2 Mammalia Mammalia 38BGG@33154,3BEPH@33208,3CSTM@33213,3J4SA@40674,482M0@7711,494ZV@7742,COG0617@1,KOG2159@2759 NA|NA|NA J Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family MAG.T12.39_00742 1292034.OR37_03742 7.9e-70 270.4 Caulobacterales 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1MV9U@1224,2KGIT@204458,2TUIN@28211,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase MAG.T12.39_00743 509190.Cseg_0388 9.3e-121 439.9 Caulobacterales hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Bacteria 1MWMF@1224,2KFK0@204458,2TQNC@28211,COG0408@1,COG0408@2 NA|NA|NA H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX MAG.T12.39_00744 450851.PHZ_c2873 6e-53 213.8 Caulobacterales trmL 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1RCY4@1224,2KGWE@204458,2U78W@28211,COG0219@1,COG0219@2 NA|NA|NA J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide MAG.T12.39_00745 59538.XP_005976336.1 5.5e-79 300.4 Cetartiodactyla Mammalia 38FY0@33154,3BE7D@33208,3CTBE@33213,3J89R@40674,48A24@7711,48X95@7742,4J44T@91561,COG0723@1,KOG1671@2759 NA|NA|NA C Cytochrome b-c1 complex subunit Rieske MAG.T12.39_00746 450851.PHZ_c2871 3.4e-215 754.2 Caulobacterales petB ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 ko00000,ko00001,ko00002,ko00194,ko03029 Bacteria 1MV97@1224,2KEYE@204458,2TSZ3@28211,COG1290@1,COG1290@2 NA|NA|NA C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis MAG.T12.39_00747 450851.PHZ_c2870 1.6e-117 429.1 Caulobacterales petC ko:K00410,ko:K00412,ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 ko00000,ko00001,ko00002,ko03029 iIT341.HP1538 Bacteria 1QFU2@1224,2KG22@204458,2TUHX@28211,COG2857@1,COG2857@2 NA|NA|NA P Cytochrome C1 MAG.T12.39_00748 450851.PHZ_c2865 1.5e-168 599.0 Caulobacterales ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 1MVM4@1224,2KF21@204458,2TRAD@28211,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner MAG.T12.39_00749 450851.PHZ_c2864 1.1e-80 306.2 Caulobacterales pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1MX1P@1224,2KFUJ@204458,2TT6Q@28211,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis MAG.T12.39_00750 450851.PHZ_c2863 9.5e-77 293.1 Caulobacterales ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 1RDH0@1224,2KGBD@204458,2U5P0@28211,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance MAG.T12.39_00751 450851.PHZ_c2862 2.6e-61 242.7 Caulobacterales Bacteria 1RC8W@1224,28NKZ@1,2KGBM@204458,2U6TS@28211,2ZBMK@2 NA|NA|NA MAG.T12.39_00752 450851.PHZ_c2861 7.7e-54 216.5 Caulobacterales prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 1MW21@1224,2KFEU@204458,2TR4Y@28211,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) MAG.T12.39_00753 190650.CC_0521 2.1e-47 194.9 Caulobacterales glnK GO:0003674,GO:0005488,GO:0005515,GO:0006808,GO:0008150,GO:0042802,GO:0045848,GO:0048518,GO:0050789,GO:0065007 ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 1RGWK@1224,2KIS5@204458,2UBE2@28211,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family MAG.T12.39_00754 935261.JAGL01000011_gene1950 2.4e-116 425.2 Phyllobacteriaceae rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 1MU0X@1224,2TQPI@28211,43H3C@69277,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis MAG.T12.39_00755 426117.M446_5837 1.6e-75 289.7 Methylobacteriaceae rfbD GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 iECSF_1327.ECSF_1929,iEcHS_1320.EcHS_A2180 Bacteria 1JREW@119045,1MUXM@1224,2TSP6@28211,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose MAG.T12.39_00756 450851.PHZ_c0111 4.2e-50 204.1 Caulobacterales rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RH3A@1224,2KGTJ@204458,2U9DF@28211,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site MAG.T12.39_00757 450851.PHZ_c0112 1.7e-112 412.1 Caulobacterales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1MUN1@1224,2KFCZ@204458,2TSIZ@28211,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family MAG.T12.39_00758 450851.PHZ_c0113 2.5e-110 405.2 Caulobacterales tesB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1MV9R@1224,2KF13@204458,2TRFD@28211,COG1946@1,COG1946@2 NA|NA|NA I Acyl-CoA thioesterase MAG.T12.39_00759 450851.PHZ_c0115 8.2e-53 213.4 Caulobacterales rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1MWQR@1224,2KGQ7@204458,2U9UT@28211,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes MAG.T12.39_00760 1382303.JPOM01000001_gene727 3.2e-43 181.4 Caulobacterales rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1MZCT@1224,2KGHZ@204458,2U94X@28211,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family MAG.T12.39_00761 450851.PHZ_c0117 7.2e-209 733.4 Caulobacterales ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1MVIA@1224,2KFSK@204458,2TQSW@28211,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components MAG.T12.39_00762 450851.PHZ_c0120 5.3e-295 1020.0 Caulobacterales dcp GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5,3.4.24.70 ko:K01284,ko:K01414 ko00000,ko01000,ko01002 Bacteria 1MU1K@1224,2KFGC@204458,2TRCK@28211,COG0339@1,COG0339@2 NA|NA|NA E peptidase MAG.T12.39_00763 450851.PHZ_c0121 1.2e-125 456.1 Caulobacterales murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_0547 Bacteria 1NAI2@1224,2KFM7@204458,2TSR7@28211,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis MAG.T12.39_00764 1122603.ATVI01000010_gene1022 4.3e-51 208.0 Xanthomonadales MA20_19220 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1RHSK@1224,1S7VQ@1236,1XBYQ@135614,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain MAG.T12.39_00765 509190.Cseg_2828 2.3e-37 161.8 Caulobacterales Bacteria 1N1W9@1224,2KH0W@204458,2UBZV@28211,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) MAG.T12.39_00766 450851.PHZ_c1280 5.6e-95 354.0 Caulobacterales lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 Bacteria 1MU6A@1224,2KFEP@204458,2TRXJ@28211,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate MAG.T12.39_00767 366602.Caul_3160 7.5e-31 139.4 Caulobacterales fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1N1JC@1224,2KH20@204458,2UC3S@28211,COG1886@1,COG1886@2 NA|NA|NA NU PFAM surface presentation of antigens (SPOA) protein MAG.T12.39_00769 1292034.OR37_02384 9.9e-136 490.3 Caulobacterales mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 1MW24@1224,2KG4Z@204458,2TRWK@28211,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter MAG.T12.39_00770 1382303.JPOM01000001_gene2383 1.6e-176 625.5 Caulobacterales ivd 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUDR@1224,2KFW4@204458,2TREJ@28211,COG1960@1,COG1960@2 NA|NA|NA C Dehydrogenase MAG.T12.39_00771 69395.JQLZ01000002_gene1106 3.5e-183 648.3 Caulobacterales GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0044424,GO:0044444,GO:0044464 ko:K07001,ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1MUM9@1224,2KFNX@204458,2TVQR@28211,COG0664@1,COG0664@2,COG1752@1,COG1752@2 NA|NA|NA T cyclic nucleotide-binding MAG.T12.39_00772 450851.PHZ_c3024 2.1e-251 874.8 Caulobacterales mccB 2.1.3.15,6.4.1.3,6.4.1.4 ko:K01966,ko:K01969,ko:K15052 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01130,map01200 M00036,M00373,M00376,M00741 R01859,R04138 RC00097,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVAX@1224,2KFBN@204458,2TRA0@28211,COG4799@1,COG4799@2 NA|NA|NA I carboxyl transferase MAG.T12.39_00773 450851.PHZ_c1289 2.2e-82 312.4 Caulobacterales 4.2.1.18,4.2.1.57 ko:K13766,ko:K13779 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R02085,R03493 RC00941,RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVEC@1224,2KFX3@204458,2TRPS@28211,COG1024@1,COG1024@2 NA|NA|NA I enoyl-CoA hydratase MAG.T12.39_00774 509190.Cseg_2818 2.4e-66 259.2 Caulobacterales Bacteria 1N1WR@1224,2KHFX@204458,2UFCV@28211,COG1566@1,COG1566@2 NA|NA|NA V Protein of unknown function (DUF3667) MAG.T12.39_00775 392499.Swit_2163 1.4e-190 672.9 Sphingomonadales 6.4.1.1,6.4.1.4 ko:K01960,ko:K01968 ko00020,ko00280,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00280,map00620,map00720,map01100,map01120,map01200,map01230 M00036,M00173,M00620 R00344,R04138 RC00040,RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 Bacteria 1P6RE@1224,2K27B@204457,2TRC2@28211,COG4770@1,COG4770@2 NA|NA|NA I acetyl propionyl-CoA carboxylase, alpha subunit MAG.T12.39_00776 1292034.OR37_02397 4.1e-44 184.1 Caulobacterales MA20_36070 Bacteria 1N054@1224,2KGNY@204458,2UBY1@28211,COG5458@1,COG5458@2 NA|NA|NA S Protein of unknown function (DUF1489) MAG.T12.39_00777 450851.PHZ_c1293 1.9e-105 389.0 Caulobacterales panC GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144 Bacteria 1MV1S@1224,2KFAU@204458,2TS2D@28211,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate MAG.T12.39_00778 450851.PHZ_c1294 1.3e-100 372.9 Caulobacterales mipZ ko:K03496 ko00000,ko03036,ko04812 Bacteria 1MVKR@1224,2KF59@204458,2TRZY@28211,COG1192@1,COG1192@2 NA|NA|NA D ATPase MipZ MAG.T12.39_00779 69395.JQLZ01000002_gene1096 1.4e-11 76.3 Bacteria Bacteria COG2214@1,COG2214@2 NA|NA|NA O Heat shock protein DnaJ domain protein MAG.T12.39_00780 1280947.HY30_13840 7.5e-97 360.1 Alphaproteobacteria folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY3N@1224,2U7XT@28211,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase MAG.T12.39_00781 1280947.HY30_13835 5.3e-53 213.8 Hyphomonadaceae Bacteria 1R2KV@1224,2TZMW@28211,440DH@69657,COG3431@1,COG3431@2 NA|NA|NA S Sensors of blue-light using FAD MAG.T12.39_00782 450851.PHZ_c1296 8e-116 424.1 Caulobacterales 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1MUU7@1224,2KF54@204458,2TRCV@28211,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family MAG.T12.39_00783 450851.PHZ_c1297 1.8e-29 135.6 Caulobacterales MA20_36110 Bacteria 1MZW0@1224,2KGR7@204458,2UC4T@28211,COG5490@1,COG5490@2 NA|NA|NA S phasin family MAG.T12.39_00784 450851.PHZ_c0124 6.6e-122 443.7 Caulobacterales oxyR ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1MVA1@1224,2KFKI@204458,2TSUS@28211,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00785 450851.PHZ_c0125 3.4e-270 937.6 Caulobacterales ppcE 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 1NZ7N@1224,2KIC5@204458,2TTAX@28211,COG1505@1,COG1505@2 NA|NA|NA E Prolyl oligopeptidase, N-terminal beta-propeller domain MAG.T12.39_00786 450851.PHZ_c0127 1.4e-83 316.2 Caulobacterales dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWDH@1224,2KFK1@204458,2TUF2@28211,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan MAG.T12.39_00787 450851.PHZ_c0128 4.7e-185 654.1 Caulobacterales mtaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 R10649 RC00003,RC03221 ko00000,ko01000,ko03016 Bacteria 1MUCS@1224,2KF66@204458,2TRYD@28211,COG0621@1,COG0621@2 NA|NA|NA J Uncharacterized protein family UPF0004 MAG.T12.39_00788 450851.PHZ_c0131 3.1e-138 498.0 Caulobacterales ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1MUDU@1224,2KF7V@204458,2TS0M@28211,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components MAG.T12.39_00789 450851.PHZ_c0132 1.1e-45 189.9 Caulobacterales ispZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K06190 ko00000 Bacteria 1NWIZ@1224,2KH3J@204458,2U74X@28211,COG2917@1,COG2917@2 NA|NA|NA D probably involved in intracellular septation MAG.T12.39_00790 1229204.AMYY01000016_gene289 3.6e-26 124.8 Alphaproteobacteria ko:K06075,ko:K22296 ko00000,ko03000 Bacteria 1RJPG@1224,2TUJP@28211,COG1846@1,COG1846@2 NA|NA|NA K MarR family MAG.T12.39_00792 450851.PHZ_c0135 4.9e-53 214.2 Caulobacterales ccmG ko:K02199 ko00000,ko03110 Bacteria 1RI3N@1224,2KGTD@204458,2TSEW@28211,COG0526@1,COG0526@2 NA|NA|NA CO TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE MAG.T12.39_00794 450851.PHZ_c0136 7.1e-98 363.6 Caulobacterales ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 ko:K02195 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko02000 3.A.1.107 iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Bacteria 1MU61@1224,2KF9U@204458,2TSW8@28211,COG0755@1,COG0755@2 NA|NA|NA U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes MAG.T12.39_00795 69395.JQLZ01000009_gene1910 1e-18 100.1 Caulobacterales Bacteria 1Q8VF@1224,2AMMJ@1,2KJE3@204458,2UYYT@28211,31CHM@2 NA|NA|NA S LTXXQ motif family protein MAG.T12.39_00796 450851.PHZ_c0139 1.2e-83 316.2 Caulobacterales ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193,ko:K02194 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 iECO111_1330.ECO111_2936,iYL1228.KPN_02080 Bacteria 1NJB0@1224,2KGG3@204458,2TUSG@28211,COG2386@1,COG2386@2 NA|NA|NA U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes MAG.T12.39_00797 450851.PHZ_c0140 2.3e-62 245.4 Caulobacterales ccmA GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015232,GO:0015399,GO:0015405,GO:0015439,GO:0015886,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1901678 3.6.3.41 ko:K02193 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 Bacteria 1MZPC@1224,2KGHP@204458,2TVBT@28211,COG4133@1,COG4133@2 NA|NA|NA P once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system MAG.T12.39_00798 450851.PHZ_c0141 0.0 1588.2 Caulobacterales acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547 Bacteria 1MU9T@1224,2KFWT@204458,2TT3T@28211,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate MAG.T12.39_00799 450851.PHZ_c0142 2e-57 229.2 Caulobacterales Bacteria 1MW6R@1224,2KGK1@204458,2U33F@28211,COG5429@1,COG5429@2 NA|NA|NA S Protein of unknown function (DUF1223) MAG.T12.39_00800 450851.PHZ_c0143 6e-36 156.8 Caulobacterales MA20_43795 Bacteria 1MZHB@1224,2CCMQ@1,2KH0G@204458,2UCC9@28211,32RW3@2 NA|NA|NA S Protein of unknown function (DUF2794) MAG.T12.39_00801 450851.PHZ_c0145 2.4e-93 348.6 Caulobacterales ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1MU69@1224,2KEXB@204458,2TRSF@28211,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family MAG.T12.39_00802 1292034.OR37_01341 3.3e-47 194.9 Caulobacterales ligT 3.1.4.58 ko:K01975 ko00000,ko01000,ko03016 Bacteria 1RDB2@1224,2KGUZ@204458,2U7FV@28211,COG1514@1,COG1514@2 NA|NA|NA J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester MAG.T12.39_00803 1292034.OR37_01340 1e-89 336.7 Caulobacterales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1MX02@1224,2KI1V@204458,2TSUR@28211,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin MAG.T12.39_00804 450851.PHZ_c0167 4.4e-111 407.9 Caulobacterales MA20_24380 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 R11945 RC00061 ko00000,ko00001,ko01000 Bacteria 1MW54@1224,2KFMR@204458,2TQMD@28211,COG0702@1,COG0702@2 NA|NA|NA GM PFAM NAD-dependent epimerase dehydratase MAG.T12.39_00806 509190.Cseg_4088 1.4e-91 342.4 Caulobacterales rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 1MWFD@1224,2KG1C@204458,2TQXS@28211,COG0349@1,COG0349@2 NA|NA|NA L 3'-5' exonuclease MAG.T12.39_00807 450851.PHZ_c0172 2.1e-42 179.1 Caulobacterales ko:K11719 ko00000,ko02000 1.B.42.1 Bacteria 1N7GD@1224,2KH4U@204458,2UF6A@28211,COG5375@1,COG5375@2 NA|NA|NA S Lipopolysaccharide-assembly, LptC-related MAG.T12.39_00808 450851.PHZ_c0173 1.6e-33 149.4 Caulobacterales lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 ko:K09774 ko00000,ko02000 1.B.42.1 iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 Bacteria 1MXGA@1224,2KH0K@204458,2U6DD@28211,COG1934@1,COG1934@2 NA|NA|NA S OstA-like protein MAG.T12.39_00809 69395.JQLZ01000009_gene1833 4.6e-105 387.5 Caulobacterales lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 1MU8M@1224,2KFFX@204458,2TR7F@28211,COG1137@1,COG1137@2 NA|NA|NA S ABC transporter MAG.T12.39_00810 402881.Plav_3137 2.8e-229 801.2 Alphaproteobacteria ko:K01138 ko00000,ko01000 Bacteria 1MWY7@1224,2TV04@28211,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T12.39_00811 69395.JQLZ01000010_gene4144 1.8e-80 306.2 Caulobacterales Bacteria 1RATF@1224,2KK10@204458,2U7XH@28211,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T12.39_00812 450851.PHZ_c0178 2.6e-187 661.8 Caulobacterales rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 1MW4V@1224,2KFNY@204458,2TS41@28211,COG1508@1,COG1508@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T12.39_00813 450851.PHZ_c0180 5.9e-64 250.8 Caulobacterales hpf GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808,ko:K05809 ko00000,ko03009 Bacteria 1MZHW@1224,2KGCV@204458,2TV3J@28211,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase MAG.T12.39_00814 69395.JQLZ01000009_gene1829 5.3e-33 147.5 Caulobacterales ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 1RD0E@1224,2KGQZ@204458,2U7B0@28211,COG1762@1,COG1762@2 NA|NA|NA G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 MAG.T12.39_00815 450851.PHZ_c0182 1.2e-26 125.6 Caulobacterales MA20_24245 Bacteria 1PUFX@1224,2KH5C@204458,2V64U@28211,COG5568@1,COG5568@2 NA|NA|NA S Protein of unknown function (DUF1150) MAG.T12.39_00816 450851.PHZ_c0183 1.2e-52 212.6 Caulobacterales ibpB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0010035,GO:0010038,GO:0042221,GO:0042802,GO:0044424,GO:0044464,GO:0046688,GO:0050896,GO:0097501,GO:1990169 ko:K04080,ko:K04081,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1R9Y1@1224,2KGJ1@204458,2UA1J@28211,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T12.39_00817 1121124.JNIX01000003_gene1072 1e-144 520.4 Caulobacterales wxcD Bacteria 1NPA5@1224,2KI8A@204458,2TSGM@28211,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T12.39_00819 715226.ABI_02230 1.9e-27 129.0 Caulobacterales MA20_24185 Bacteria 1MZMM@1224,2KH09@204458,2V53M@28211,COG4530@1,COG4530@2 NA|NA|NA S Protein of unknown function (FYDLN_acid) MAG.T12.39_00820 450851.PHZ_c0188 8.8e-179 633.3 Caulobacterales aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0345 Bacteria 1MWMK@1224,2KFNC@204458,2TR6W@28211,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate MAG.T12.39_00821 190650.CC_3588 5.5e-70 270.8 Caulobacterales cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1MUUD@1224,2KGEG@204458,2U71H@28211,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily MAG.T12.39_00822 1292034.OR37_01264 1.1e-293 1015.4 Caulobacterales rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1MVAV@1224,2KF4I@204458,2TQPV@28211,COG0539@1,COG0539@2 NA|NA|NA J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence MAG.T12.39_00823 69395.JQLZ01000009_gene1821 9.3e-37 159.5 Caulobacterales himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 ko:K05788 ko00000,ko03032,ko03036,ko03400 Bacteria 1MZ7M@1224,2KGZD@204458,2UBR5@28211,COG0776@1,COG0776@2 NA|NA|NA K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control MAG.T12.39_00824 1229204.AMYY01000003_gene950 2.4e-42 178.3 unclassified Alphaproteobacteria mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1RHG8@1224,2U99Y@28211,4BQMS@82117,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell MAG.T12.39_00825 450851.PHZ_c0194 1.1e-70 273.1 Caulobacterales trpF 4.1.1.48,5.3.1.24 ko:K01817,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1RA87@1224,2KGDM@204458,2U7CH@28211,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family MAG.T12.39_00826 450851.PHZ_c0195 7e-199 699.9 Caulobacterales trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUS8@1224,2KFB5@204458,2TSHK@28211,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine MAG.T12.39_00827 450851.PHZ_c0196 1.1e-105 389.8 Caulobacterales trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXJV@1224,2KG0U@204458,2TQN2@28211,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate MAG.T12.39_00828 450851.PHZ_c0197 3.3e-132 478.0 Caulobacterales accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 1MW8G@1224,2KFRF@204458,2TRSH@28211,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA MAG.T12.39_00829 450851.PHZ_c0198 1.6e-164 585.9 Caulobacterales folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2475,iJN746.PP_1997,iSDY_1059.SDY_2514 Bacteria 1MVCH@1224,2KF63@204458,2TR64@28211,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family MAG.T12.39_00830 1292034.OR37_01605 1.6e-46 191.8 Caulobacterales trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291 Bacteria 1MZBB@1224,2KGP3@204458,2UCCR@28211,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family MAG.T12.39_00831 450851.PHZ_c0200 8.2e-285 986.9 Caulobacterales addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1MUTF@1224,2KFNF@204458,2TQJZ@28211,COG1074@1,COG1074@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily MAG.T12.39_00832 450851.PHZ_c0201 2.5e-290 1005.0 Caulobacterales addB 3.1.11.5,3.6.4.12 ko:K01144,ko:K02259,ko:K16899 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko01000,ko03029,ko03400 3.D.4.4 Bacteria 1MY2G@1224,2KG11@204458,2TS74@28211,COG2887@1,COG2887@2,COG3893@1,COG3893@2 NA|NA|NA L double-strand break repair protein AddB MAG.T12.39_00833 450851.PHZ_c0202 2.9e-88 331.6 Caulobacterales rmlA GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 ko:K00966,ko:K00973,ko:K00992 ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130 M00114,M00361,M00362,M00793 R00885,R02328,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1R9ZD@1224,2KGEF@204458,2TU2V@28211,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase MAG.T12.39_00834 69395.JQLZ01000011_gene3564 2.5e-123 448.7 Caulobacterales MA20_24090 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1MXCH@1224,2KEXH@204458,2TSJD@28211,COG3178@1,COG3178@2 NA|NA|NA S Phosphotransferase MAG.T12.39_00835 1449049.JONW01000005_gene1853 5.8e-50 203.8 Caulobacterales yjeE 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1RGYU@1224,2KH0R@204458,2UBQ9@28211,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE MAG.T12.39_00836 1382303.JPOM01000001_gene242 3.6e-101 374.8 Caulobacterales Bacteria 1QU3F@1224,2KG3R@204458,2U0QJ@28211,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T12.39_00837 1449049.JONW01000011_gene2204 2.6e-235 821.2 Caulobacterales mmsA 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUHV@1224,2KF4K@204458,2TSMD@28211,COG1012@1,COG1012@2 NA|NA|NA C Methylmalonate-semialdehyde dehydrogenase MAG.T12.39_00838 1122132.AQYH01000002_gene1438 7.3e-101 373.6 Rhizobiaceae Bacteria 1MVBT@1224,28M8G@1,2TTGC@28211,2ZAMM@2,4B7AN@82115 NA|NA|NA S RES MAG.T12.39_00839 1122132.AQYH01000002_gene1439 5.6e-38 163.7 Rhizobiaceae Bacteria 1N2DF@1224,2UAZK@28211,4BM1B@82115,COG5642@1,COG5642@2 NA|NA|NA S Protein of unknown function (DUF2384) MAG.T12.39_00840 450851.PHZ_c0207 5.1e-164 583.9 Caulobacterales zapE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 3.6.4.7 ko:K06916,ko:K18798 ko00000,ko01000,ko03029,ko03036 Bacteria 1MUUW@1224,2KF8I@204458,2TRG1@28211,COG1485@1,COG1485@2 NA|NA|NA S PFAM AFG1-family ATPase MAG.T12.39_00841 450851.PHZ_c0210 2.2e-33 148.7 Caulobacterales sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 1N02N@1224,2KH2P@204458,2UC47@28211,COG2009@1,COG2009@2 NA|NA|NA C Succinate dehydrogenase, cytochrome b556 subunit MAG.T12.39_00842 450851.PHZ_c0211 2.9e-34 151.4 Caulobacterales sdhD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 1MZND@1224,2KK3B@204458,2UC3G@28211,COG2142@1,COG2142@2 NA|NA|NA C TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein MAG.T12.39_00843 450851.PHZ_c0212 0.0 1103.2 Caulobacterales sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5M@1224,2KF7R@204458,2TQJA@28211,COG1053@1,COG1053@2 NA|NA|NA C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily MAG.T12.39_00844 190650.CC_3526 8.9e-139 499.6 Caulobacterales sdhB 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVHS@1224,2KFMG@204458,2TQYF@28211,COG0479@1,COG0479@2 NA|NA|NA C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family MAG.T12.39_00845 450851.PHZ_c0214 7.4e-172 610.1 Caulobacterales padH 1.18.1.3,1.2.1.58 ko:K00529,ko:K18359 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R02450,R06782,R06783 RC00004,RC00098,RC02860 br01601,br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 1MW58@1224,2KJVV@204458,2TW0G@28211,COG1251@1,COG1251@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase MAG.T12.39_00846 190650.CC_3524 1.5e-47 195.3 Caulobacterales fdx ko:K04755 ko00000 Bacteria 1RHDC@1224,2KGS1@204458,2U97J@28211,COG0633@1,COG0633@2 NA|NA|NA C ferredoxin MAG.T12.39_00847 450851.PHZ_c0218 3.4e-287 994.2 Caulobacterales Bacteria 1MVY8@1224,2KFFA@204458,2TS5B@28211,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T12.39_00848 450851.PHZ_c0219 2.2e-30 139.0 Caulobacterales Bacteria 1N9TQ@1224,2E8FV@1,2KH9C@204458,2UIUE@28211,332U5@2 NA|NA|NA MAG.T12.39_00849 509190.Cseg_0215 4.1e-47 194.1 Caulobacterales MA20_43655 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1N18M@1224,2KGNW@204458,2UBUK@28211,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase MAG.T12.39_00850 450851.PHZ_c0223 4.7e-38 164.5 Caulobacterales ko:K03098 ko00000,ko04147 Bacteria 1RDAI@1224,2KJ7T@204458,2U723@28211,COG3040@1,COG3040@2 NA|NA|NA M Lipocalin-like domain MAG.T12.39_00851 450851.PHZ_c0224 1.2e-46 192.6 Caulobacterales MA20_23405 Bacteria 1RDXW@1224,2KGGM@204458,2U73Y@28211,COG5321@1,COG5321@2 NA|NA|NA S DNA repair protein MmcB-like MAG.T12.39_00852 633149.Bresu_0526 7.4e-45 187.2 Caulobacterales regA GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 ko:K15012 ko02020,map02020 M00523 ko00000,ko00001,ko00002,ko02022 Bacteria 1RD7J@1224,2KG0V@204458,2TSK7@28211,COG4567@1,COG4567@2 NA|NA|NA T PFAM response regulator receiver MAG.T12.39_00853 573065.Astex_0221 7.1e-51 207.2 Caulobacterales hyaE GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 ko:K03619,ko:K07152 ko00000,ko03029 Bacteria 1RHJ8@1224,2KGHR@204458,2U9DV@28211,COG1999@1,COG1999@2 NA|NA|NA S PFAM electron transport protein SCO1 SenC MAG.T12.39_00854 450851.PHZ_c0229 1.1e-191 676.0 Caulobacterales phaZ 3.1.1.75 ko:K05973 ko00650,map00650 R05118 ko00000,ko00001,ko01000 Bacteria 1MVUH@1224,2KFHX@204458,2TQXW@28211,COG4553@1,COG4553@2 NA|NA|NA I Polyhydroxyalkanoate depolymerase, intracellular MAG.T12.39_00855 450851.PHZ_c0230 2.2e-70 272.3 Caulobacterales MA20_23375 ko:K07043 ko00000 Bacteria 1MXZU@1224,2KGKK@204458,2U1JG@28211,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 MAG.T12.39_00856 1292034.OR37_03982 1.4e-260 905.6 Caulobacterales mrcB 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1QTST@1224,2KFD2@204458,2TQQ8@28211,COG0744@1,COG0744@2 NA|NA|NA M Penicillin-binding protein, 1A family MAG.T12.39_00858 1382303.JPOM01000001_gene1276 3.8e-45 188.0 Caulobacterales atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 Bacteria 1MVRH@1224,2KGEU@204458,2U5IC@28211,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T12.39_00859 450851.PHZ_c0235 1.7e-255 888.3 Caulobacterales atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1MUG7@1224,2KG49@204458,2TQYK@28211,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit MAG.T12.39_00860 450851.PHZ_c0236 1.3e-119 436.0 Caulobacterales atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 1MU28@1224,2KFFB@204458,2TR11@28211,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex MAG.T12.39_00861 450851.PHZ_c0237 2.5e-249 867.8 Caulobacterales atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 Bacteria 1MUFU@1224,2KEYF@204458,2TRGP@28211,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits MAG.T12.39_00862 450851.PHZ_c0238 2.1e-28 131.3 Caulobacterales atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02113,ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1RHE4@1224,2KGZN@204458,2UBXX@28211,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane MAG.T12.39_00863 450851.PHZ_c0239 9.8e-21 107.1 Caulobacterales Bacteria 1P0VX@1224,2C9CE@1,2KJB7@204458,2UUUI@28211,34A8F@2 NA|NA|NA MAG.T12.39_00864 450851.PHZ_c0241 4e-75 288.1 Caulobacterales Bacteria 1RD1F@1224,2KGFW@204458,2U8TC@28211,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T12.39_00865 59538.XP_005978137.1 5.8e-56 223.8 Eukaryota GO:0003674,GO:0003824,GO:0004551,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008893,GO:0009507,GO:0009536,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016794,GO:0016817,GO:0016818,GO:0019637,GO:0034432,GO:0034641,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:1901360 Eukaryota 2QSDR@2759,COG0494@1 NA|NA|NA L guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity MAG.T12.39_00866 1382303.JPOM01000001_gene1236 7.2e-81 307.8 Caulobacterales ko:K09798 ko00000 Bacteria 1N3JP@1224,2KF3P@204458,2TUFD@28211,COG2861@1,COG2861@2 NA|NA|NA S Divergent polysaccharide deacetylase MAG.T12.39_00867 450851.PHZ_c0244 2.2e-188 665.2 Caulobacterales ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1MU39@1224,2KG4V@204458,2TRW2@28211,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T12.39_00868 1121123.AUAO01000002_gene279 1.1e-15 90.5 Caulobacterales filA ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1MY3E@1224,2KGRU@204458,2TUSP@28211,COG4942@1,COG4942@2 NA|NA|NA D Peptidase, M23 MAG.T12.39_00869 450851.PHZ_c0246 2.3e-62 245.0 Caulobacterales rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1R9Z2@1224,2KGVF@204458,2U95Q@28211,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA MAG.T12.39_00870 1280944.HY17_04370 3.7e-127 461.8 Hyphomonadaceae zhuL 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1MW3Z@1224,2TS56@28211,43X34@69657,COG0154@1,COG0154@2 NA|NA|NA J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases MAG.T12.39_00871 1121124.JNIX01000002_gene107 4.9e-35 153.3 Caulobacterales rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1MZEF@1224,2KGTH@204458,2UBSV@28211,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation MAG.T12.39_00872 69395.JQLZ01000006_gene2033 2.1e-76 292.0 Caulobacterales nadD 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1RD0J@1224,2KG6Z@204458,2U6ZC@28211,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) MAG.T12.39_00873 450851.PHZ_c0252 6.7e-186 657.1 Caulobacterales proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41,1.2.1.81 ko:K00147,ko:K15515 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iYO844.BSU13130 Bacteria 1MUGJ@1224,2KEZN@204458,2TS83@28211,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate MAG.T12.39_00874 1292034.OR37_01670 3e-277 961.1 Caulobacterales iorB 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 1QTTJ@1224,2KFXR@204458,2TQVK@28211,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MAG.T12.39_00875 1292034.OR37_01671 4.4e-58 230.7 Caulobacterales 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 1RD8C@1224,2KGN6@204458,2U6Z6@28211,COG2080@1,COG2080@2 NA|NA|NA C 2Fe-2S -binding domain protein MAG.T12.39_00876 450851.PHZ_c0286 3.2e-19 101.3 Caulobacterales ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1MZGS@1224,2KJ4S@204458,2UFAV@28211,COG3474@1,COG3474@2 NA|NA|NA C Cytochrome c MAG.T12.39_00877 450851.PHZ_c0287 8.1e-56 224.2 Caulobacterales cysG GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.1.1.131,3.7.1.12,4.2.1.75,4.99.1.3,4.99.1.4 ko:K02302,ko:K02303,ko:K02304,ko:K03795,ko:K13541,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947,R05180,R05807,R05809,R07772 RC00003,RC00871,RC01012,RC01034,RC01293,RC01545,RC01861,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158 Bacteria 1RFEE@1224,2KGHX@204458,2U73H@28211,COG0007@1,COG0007@2,COG1648@1,COG1648@2 NA|NA|NA H Sirohaem synthase dimerisation region MAG.T12.39_00878 450851.PHZ_c0289 1.3e-224 785.8 Caulobacterales ko:K03761,ko:K03762 ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 Bacteria 1MU46@1224,2KEXI@204458,2TRAP@28211,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator MAG.T12.39_00879 450851.PHZ_c0291 5.8e-198 696.8 Caulobacterales gcdH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUK0@1224,2KF9R@204458,2TSAC@28211,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T12.39_00880 450851.PHZ_c0294 1.2e-95 356.3 Caulobacterales cysQ 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1N0GY@1224,2KGGX@204458,2TT7B@28211,COG1218@1,COG1218@2 NA|NA|NA P nucleotidase MAG.T12.39_00881 450851.PHZ_c0296 2.1e-72 278.9 Caulobacterales chpT ko:K13588 ko02020,ko04112,map02020,map04112 ko00000,ko00001 Bacteria 1MVEY@1224,2KGE8@204458,2TSE6@28211,COG5385@1,COG5385@2 NA|NA|NA S Histidine phosphotransferase C-terminal domain MAG.T12.39_00882 190650.CC_3471 5.9e-37 160.2 Caulobacterales Bacteria 1QU38@1224,2KJVF@204458,2TVXD@28211,COG0745@1,COG0745@2 NA|NA|NA T cheY-homologous receiver domain MAG.T12.39_00883 366602.Caul_0095 1.7e-50 206.5 Caulobacterales cheR 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 Bacteria 1MU6W@1224,2KGDX@204458,2TRQ3@28211,COG1352@1,COG1352@2 NA|NA|NA NT Methyltransferase MAG.T12.39_00885 450851.PHZ_c0310 8.7e-16 89.7 Bacteria Bacteria COG4575@1,COG4575@2 NA|NA|NA T ribosome binding MAG.T12.39_00886 402881.Plav_2623 1.5e-96 359.4 Alphaproteobacteria hydD 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 Bacteria 1PFMC@1224,2UG1M@28211,COG2267@1,COG2267@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T12.39_00887 1054213.HMPREF9946_01700 3.5e-66 257.7 Rhodospirillales MA20_44940 Bacteria 1RB8W@1224,2JW9D@204441,2TUPM@28211,COG4101@1,COG4101@2 NA|NA|NA G Cupin MAG.T12.39_00888 69395.JQLZ01000001_gene3032 2e-109 403.3 Caulobacterales prtA 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1MU7T@1224,2KHJV@204458,2TRVY@28211,COG2931@1,COG2931@2 NA|NA|NA Q Zinc-dependent metalloprotease MAG.T12.39_00891 450851.PHZ_c0612 4.9e-227 793.9 Caulobacterales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4E@1224,2KGGB@204458,2TSCY@28211,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T12.39_00892 633149.Bresu_1756 5.3e-08 65.1 Caulobacterales Bacteria 1NB58@1224,2E7B7@1,2KJYK@204458,2UHAV@28211,331UM@2 NA|NA|NA MAG.T12.39_00893 1449049.JONW01000009_gene4363 5.8e-08 65.1 Alphaproteobacteria Bacteria 1N6KN@1224,2E7B7@1,2UD50@28211,331UM@2 NA|NA|NA MAG.T12.39_00894 450851.PHZ_c3303 5.3e-155 553.9 Caulobacterales rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5E@1224,2KF7Y@204458,2TT5T@28211,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily MAG.T12.39_00895 450851.PHZ_c3302 1.7e-160 572.8 Caulobacterales matE Bacteria 1MVRV@1224,2KHDX@204458,2TS4Z@28211,COG0534@1,COG0534@2 NA|NA|NA V MatE MAG.T12.39_00896 450851.PHZ_c3301 9.2e-159 566.6 Caulobacterales Bacteria 1MVPR@1224,2KFVB@204458,2TRWZ@28211,COG1680@1,COG1680@2 NA|NA|NA V beta-lactamase MAG.T12.39_00897 450851.PHZ_c3299 2.6e-223 781.2 Caulobacterales 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU2V@1224,2KFDE@204458,2TTUF@28211,COG1960@1,COG1960@2 NA|NA|NA C Acyl-CoA dehydrogenase, C-terminal domain MAG.T12.39_00898 450851.PHZ_c3298 2.5e-266 924.5 Caulobacterales 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1MU6G@1224,2KIKM@204458,2TR2W@28211,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_00899 450851.PHZ_c3297 4.3e-58 231.1 Caulobacterales azr 1.3.5.4,1.5.1.38,1.7.1.6 ko:K00244,ko:K00299,ko:K03206 ko00020,ko00190,ko00620,ko00650,ko00720,ko00740,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map00740,map00920,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164,R05706,R07210,R10206 RC00045,RC00126,RC01779,RC02556 ko00000,ko00001,ko00002,ko01000 Bacteria 1RBUB@1224,2KIWW@204458,2VG86@28211,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase MAG.T12.39_00900 450851.PHZ_c3296 1.7e-178 632.1 Caulobacterales ribB 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0516 Bacteria 1MU8P@1224,2KFQS@204458,2TSMA@28211,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate MAG.T12.39_00901 450851.PHZ_c3293 6.8e-89 333.6 Caulobacterales MA20_20925 ko:K09987 ko00000 Bacteria 1MVR2@1224,2KG4Q@204458,2TT8Z@28211,COG3820@1,COG3820@2 NA|NA|NA S Protein of unknown function (DUF1013) MAG.T12.39_00902 1120956.JHZK01000029_gene46 3.2e-07 60.5 Rhodobiaceae Bacteria 1JPIX@119043,1Q4FW@1224,2VAXW@28211,COG5570@1,COG5570@2 NA|NA|NA S Protein of unknown function (DUF465) MAG.T12.39_00903 1292034.OR37_00941 5.1e-12 76.6 Caulobacterales MA20_03740 Bacteria 1NG9U@1224,2KHHR@204458,2UFXJ@28211,COG5481@1,COG5481@2 NA|NA|NA S Protein of unknown function (DUF465) MAG.T12.39_00904 1292034.OR37_00939 1.1e-71 276.6 Caulobacterales 2.7.7.65 ko:K21021 ko02025,map02025 ko00000,ko00001,ko01000 Bacteria 1Q7FU@1224,2KGRI@204458,2TRE7@28211,COG2199@1,COG2199@2 NA|NA|NA T Diguanylate cyclase MAG.T12.39_00905 1229204.AMYY01000021_gene680 3.2e-62 244.6 unclassified Alphaproteobacteria purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1RCWJ@1224,2U58D@28211,4BQ8N@82117,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T12.39_00906 1035191.HMPREF0185_02924 2.4e-126 458.8 Caulobacterales purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 1MU70@1224,2KFHQ@204458,2TRSV@28211,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) MAG.T12.39_00907 1282360.ABAC460_04845 1.6e-128 465.7 Caulobacterales motA ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1MXK3@1224,2KF09@204458,2TR5A@28211,COG1291@1,COG1291@2 NA|NA|NA N With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine MAG.T12.39_00908 450851.PHZ_c3122 1.5e-162 579.3 Caulobacterales Bacteria 1MVSC@1224,2KK9A@204458,2TXB0@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T12.39_00909 450851.PHZ_c3121 1.4e-122 446.4 Caulobacterales hopAJ1 ko:K00786,ko:K08305 ko00000,ko01000,ko01011 GH103 Bacteria 1MUZ3@1224,2KFG8@204458,2TRP0@28211,COG2951@1,COG2951@2,COG3409@1,COG3409@2 NA|NA|NA M Lytic murein transglycosylase MAG.T12.39_00910 573065.Astex_1545 3.5e-13 79.7 Caulobacterales rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1NGBJ@1224,2KHEZ@204458,2UJAG@28211,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family MAG.T12.39_00911 190650.CC_3319 2.2e-28 131.3 Caulobacterales ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 1N77J@1224,2KGZ7@204458,2UFX6@28211,COG3750@1,COG3750@2 NA|NA|NA S Belongs to the UPF0335 family MAG.T12.39_00912 366602.Caul_0877 1e-25 122.9 Caulobacterales Bacteria 1N9SK@1224,2E4P4@1,2KHD4@204458,2UFQ7@28211,32ZHW@2 NA|NA|NA MAG.T12.39_00913 450851.PHZ_c3115 4e-196 691.0 Caulobacterales tacA GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 1MU0N@1224,2KFDD@204458,2TQPG@28211,COG2204@1,COG2204@2 NA|NA|NA T two component, sigma54 specific, transcriptional regulator, Fis family MAG.T12.39_00914 450851.PHZ_c3112 6.7e-298 1029.6 Caulobacterales exaA 1.1.2.8,1.1.5.5,1.1.9.1 ko:K00114,ko:K17760,ko:K22473 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 R05062,R05198,R05285,R09479 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 Bacteria 1MUQX@1224,2KF9M@204458,2TS2Q@28211,COG2010@1,COG2010@2,COG4993@1,COG4993@2 NA|NA|NA CG PQQ-like domain MAG.T12.39_00915 59538.XP_005968338.1 2.5e-29 134.4 Mammalia Mammalia 38CSR@33154,3BHTK@33208,3CS51@33213,3J5CC@40674,480T0@7711,48WVC@7742,COG0508@1,COG1249@1,KOG0557@2759,KOG1335@2759 NA|NA|NA C dihydrolipoyl dehydrogenase activity MAG.T12.39_00916 663610.JQKO01000008_gene87 3.2e-23 114.8 Alphaproteobacteria Bacteria 1R9BS@1224,28JUV@1,2TQV7@28211,2Z9JV@2 NA|NA|NA MAG.T12.39_00917 485913.Krac_4178 7.4e-12 77.4 Bacteria Bacteria 2DE8Y@1,2ZM0Q@2 NA|NA|NA S NUDIX domain MAG.T12.39_00918 450851.PHZ_c1738 2e-222 778.5 Caulobacterales aas GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008779,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019752,GO:0031224,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 iEC042_1314.EC042_3034 Bacteria 1QVGC@1224,2KFUN@204458,2TWFC@28211,COG0318@1,COG0318@2 NA|NA|NA IQ Aas bifunctional protein MAG.T12.39_00919 1382303.JPOM01000001_gene1308 3e-144 518.1 Caulobacterales lipA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1427,iB21_1397.B21_00586,iBWG_1329.BWG_0499,iE2348C_1286.E2348C_0528,iEC55989_1330.EC55989_0620,iECABU_c1320.ECABU_c06820,iECBD_1354.ECBD_3023,iECB_1328.ECB_00597,iECDH10B_1368.ECDH10B_0589,iECDH1ME8569_1439.ECDH1ME8569_0597,iECD_1391.ECD_00597,iECED1_1282.ECED1_0624,iECH74115_1262.ECH74115_0716,iECIAI1_1343.ECIAI1_0611,iECIAI39_1322.ECIAI39_0603,iECNA114_1301.ECNA114_0567,iECO103_1326.ECO103_0635,iECO111_1330.ECO111_0658,iECO26_1355.ECO26_0702,iECOK1_1307.ECOK1_0638,iECP_1309.ECP_0658,iECS88_1305.ECS88_0669,iECSE_1348.ECSE_0695,iECSF_1327.ECSF_0567,iECSP_1301.ECSP_0681,iECUMN_1333.ECUMN_0720,iECW_1372.ECW_m0682,iECs_1301.ECs0666,iEKO11_1354.EKO11_3238,iETEC_1333.ETEC_0656,iEcDH1_1363.EcDH1_2998,iEcE24377_1341.EcE24377A_0652,iEcHS_1320.EcHS_A0679,iEcSMS35_1347.EcSMS35_0648,iEcolC_1368.EcolC_3017,iG2583_1286.G2583_0791,iJO1366.b0628,iLF82_1304.LF82_1199,iNRG857_1313.NRG857_02855,iSBO_1134.SBO_0492,iSDY_1059.SDY_0550,iSF_1195.SF0653,iSFxv_1172.SFxv_0720,iSSON_1240.SSON_0582,iS_1188.S0675,iSbBS512_1146.SbBS512_E0542,iUMN146_1321.UM146_14375,iUMNK88_1353.UMNK88_663,iUTI89_1310.UTI89_C0631,iWFL_1372.ECW_m0682,iY75_1357.Y75_RS03275,ic_1306.c0718 Bacteria 1MVRD@1224,2KFRW@204458,2TRP3@28211,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives MAG.T12.39_00920 450851.PHZ_c1736 3.3e-45 188.0 Caulobacterales MA20_29700 ko:K18588 ko00000 Bacteria 1RGUH@1224,2KGPZ@204458,2U7D8@28211,COG2867@1,COG2867@2 NA|NA|NA I cyclase dehydrase MAG.T12.39_00921 450851.PHZ_c1735 1.7e-66 258.8 Caulobacterales ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1RH2Y@1224,2KGJ8@204458,2U94H@28211,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family MAG.T12.39_00922 450851.PHZ_c1733 3e-127 461.8 Caulobacterales ispF GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0008685,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0016829,GO:0016849,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.1.1.228,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00554,ko:K00991,ko:K01770,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R00597,R01525,R02921,R05633,R05637 RC00002,RC00003,RC00089,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 1MVHA@1224,2KEZB@204458,2TRQC@28211,COG0245@1,COG0245@2,COG1211@1,COG1211@2 NA|NA|NA I Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) MAG.T12.39_00923 450851.PHZ_c1732 7.6e-127 460.3 Caulobacterales dusB ko:K05539,ko:K05540 ko00000,ko01000,ko03016 Bacteria 1MV5V@1224,2KFP5@204458,2TRC8@28211,COG0042@1,COG0042@2 NA|NA|NA H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T12.39_00924 450851.PHZ_c1731 5.6e-131 474.2 Caulobacterales glnL GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07708,ko:K07710 ko02020,map02020 M00497,M00500 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MVN6@1224,2KFZV@204458,2TQS1@28211,COG3852@1,COG3852@2 NA|NA|NA T Signal transduction histidine kinase, nitrogen specific MAG.T12.39_00925 1292034.OR37_00344 1.8e-230 805.1 Caulobacterales glnG GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 ko:K07712 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KF8K@204458,2TQPG@28211,COG2204@1,COG2204@2 NA|NA|NA T nitrogen regulation protein NR(I) MAG.T12.39_00926 450851.PHZ_c1729 9.4e-234 816.6 Caulobacterales ntrY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K13598 ko02020,map02020 M00498 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWKZ@1224,2KFZT@204458,2TQTB@28211,COG5000@1,COG5000@2 NA|NA|NA T Signal transduction histidine kinase MAG.T12.39_00927 450851.PHZ_c1728 7.5e-213 746.5 Caulobacterales ntrX ko:K02481,ko:K13599 ko02020,map02020 M00498 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KFA3@204458,2TQW2@28211,COG2204@1,COG2204@2 NA|NA|NA T sigma-54 factor interaction domain-containing protein MAG.T12.39_00928 450851.PHZ_c1727 2.3e-116 425.2 Caulobacterales dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 Bacteria 1MVAT@1224,2KF88@204458,2TR7R@28211,COG0115@1,COG0115@2 NA|NA|NA EH Catalyzes the transamination of D-amino acids and their alpha-keto acids MAG.T12.39_00929 450851.PHZ_c1726 5.8e-36 156.4 Caulobacterales hfq GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 Bacteria 1MZM1@1224,2KH3P@204458,2UBTW@28211,COG1923@1,COG1923@2 NA|NA|NA J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs MAG.T12.39_00930 450851.PHZ_c1725 1.9e-170 605.5 Caulobacterales hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 ko:K03665 ko00000,ko03009 Bacteria 1MUA0@1224,2KFVT@204458,2TUXJ@28211,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis MAG.T12.39_00931 450851.PHZ_c1596 9.9e-93 346.7 Caulobacterales mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 ko:K02428,ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 Bacteria 1MVKM@1224,2KFIN@204458,2TRC9@28211,COG1694@1,COG3956@2 NA|NA|NA S TIGRFAM MazG family protein MAG.T12.39_00932 1144343.PMI41_01127 5.2e-23 112.8 Phyllobacteriaceae ko:K09946 ko00000 Bacteria 1N6P8@1224,2UGRU@28211,43M56@69277,COG3422@1,COG3422@2 NA|NA|NA S Domain of unknown function (DUF1508) MAG.T12.39_00933 426117.M446_5025 1.3e-60 239.2 Methylobacteriaceae gpo 1.11.1.22,1.11.1.9 ko:K00432,ko:K20207 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 iJN678.slr1171 Bacteria 1JUNZ@119045,1RD1R@1224,2U7R3@28211,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family MAG.T12.39_00934 1121861.KB899933_gene602 4e-33 147.9 Rhodospirillales ko:K09796 ko00000,ko03110 Bacteria 1MZ3M@1224,2JTRF@204441,2UBUR@28211,COG2847@1,COG2847@2 NA|NA|NA S protein conserved in bacteria MAG.T12.39_00936 247633.GP2143_13261 5.9e-114 417.5 unclassified Gammaproteobacteria Bacteria 1J5HH@118884,1MWAK@1224,1RNB4@1236,COG3173@1,COG3173@2 NA|NA|NA S aminoglycoside phosphotransferase MAG.T12.39_00937 1114964.L485_16425 4e-50 204.5 Sphingomonadales Bacteria 1N19W@1224,2KDA7@204457,2UD6N@28211,COG0791@1,COG0791@2 NA|NA|NA M NLP P60 protein MAG.T12.39_00938 172088.AUGA01000009_gene1790 4.6e-50 205.3 Bradyrhizobiaceae 2.7.1.89 ko:K07251,ko:K09965 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1PDP6@1224,2VBSW@28211,3JXTF@41294,COG0510@1,COG0510@2 NA|NA|NA M Choline/ethanolamine kinase MAG.T12.39_00939 1211115.ALIQ01000040_gene3080 4.6e-17 94.4 Alphaproteobacteria Bacteria 1NAES@1224,2U9CW@28211,COG2452@1,COG2452@2 NA|NA|NA L Helix-turn-helix domain MAG.T12.39_00940 216596.RL1017 1.5e-21 109.0 Rhizobiaceae Bacteria 1NDJK@1224,2UHZX@28211,4BG6A@82115,COG1694@1,COG1694@2 NA|NA|NA S Mazg nucleotide pyrophosphohydrolase MAG.T12.39_00941 450851.PHZ_c0757 2.4e-224 784.6 Caulobacterales Bacteria 1MUQH@1224,2KG0J@204458,2TTY2@28211,COG2072@1,COG2072@2 NA|NA|NA C Flavin-binding monooxygenase-like MAG.T12.39_00942 450851.PHZ_c1601 1.4e-54 219.5 Caulobacterales purN 2.1.2.2,6.3.2.6,6.3.4.13 ko:K11175,ko:K13713 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04144,R04325,R04326,R04591 RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWN1@1224,2KGK4@204458,2TRY6@28211,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate MAG.T12.39_00943 59538.XP_005968316.1 5.5e-115 420.6 Opisthokonta GO:0003674,GO:0003824,GO:0016787 Opisthokonta 2QWBK@2759,39ZXT@33154,COG1235@1 NA|NA|NA S Beta-lactamase superfamily domain MAG.T12.39_00944 450851.PHZ_c1603 7e-112 410.2 Caulobacterales ycfH GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1MUC0@1224,2KF2R@204458,2TS88@28211,COG0084@1,COG0084@2 NA|NA|NA L Hydrolase, TatD family MAG.T12.39_00945 450851.PHZ_c1604 1.1e-112 413.3 Caulobacterales holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MY1W@1224,2KF0N@204458,2TV3E@28211,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III MAG.T12.39_00946 450851.PHZ_c1605 3.1e-73 281.6 Caulobacterales tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV9C@1224,2KGC2@204458,2U72D@28211,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis MAG.T12.39_00947 247633.GP2143_09435 7.9e-103 380.9 unclassified Gammaproteobacteria Bacteria 1J957@118884,1NU31@1224,1SJUT@1236,COG0477@1,COG2814@2 NA|NA|NA EGP COG0477 Permeases of the major facilitator superfamily MAG.T12.39_00949 450851.PHZ_c0880 9.1e-147 526.9 Caulobacterales ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2KFG7@204458,2U1DI@28211,COG2211@1,COG2211@2 NA|NA|NA G PFAM major facilitator superfamily MFS_1 MAG.T12.39_00950 1248917.ANFX01000007_gene60 2.3e-39 168.7 Sphingomonadales Bacteria 1NQFV@1224,2EC7R@1,2K7H7@204457,2UMAZ@28211,33669@2 NA|NA|NA MAG.T12.39_00951 1219035.NT2_04_02110 1.4e-134 486.5 Sphingomonadales ko:K07093 ko00000 Bacteria 1Q4XN@1224,2JZXD@204457,2VBCD@28211,COG3211@1,COG3211@2 NA|NA|NA S Bacterial protein of unknown function (DUF839) MAG.T12.39_00952 987059.RBXJA2T_18478 0.0 1165.2 unclassified Burkholderiales katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 1KK94@119065,1MUBF@1224,2VH5H@28216,COG0376@1,COG0376@2 NA|NA|NA P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity MAG.T12.39_00953 450851.PHZ_c0733 3.7e-181 641.3 Caulobacterales 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1MUIC@1224,2KHWY@204458,2TRRZ@28211,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_00954 402881.Plav_0380 2.8e-239 834.7 Rhodobiaceae yjcS ko:K01138 ko00000,ko01000 Bacteria 1JPRM@119043,1MU82@1224,2TSM1@28211,COG2015@1,COG2015@2 NA|NA|NA Q Alkyl sulfatase C-terminal MAG.T12.39_00955 1216976.AX27061_2896 2.2e-138 499.2 Alcaligenaceae dan GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.81,3.5.1.83 ko:K06015,ko:K20817 R02192 RC00064,RC00328 ko00000,ko01000 Bacteria 1MWWY@1224,2VJ3D@28216,3T3B1@506,COG3653@1,COG3653@2 NA|NA|NA Q N-acyl-D-aspartate D-glutamate deacylase MAG.T12.39_00956 1280954.HPO_03874 2.7e-249 867.8 Hyphomonadaceae Bacteria 1MU6G@1224,2TR2W@28211,43Z3R@69657,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_00957 1123257.AUFV01000003_gene1004 4.8e-242 844.0 Xanthomonadales Bacteria 1MUHZ@1224,1RZ70@1236,1X4ZJ@135614,COG3975@1,COG3975@2 NA|NA|NA S protease with the C-terminal PDZ domain MAG.T12.39_00958 450851.PHZ_c1614 3.8e-17 94.0 Caulobacterales tusA ko:K04085 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Bacteria 1MZA5@1224,2KHEX@204458,2V3HP@28211,COG0425@1,COG0425@2 NA|NA|NA O Belongs to the sulfur carrier protein TusA family MAG.T12.39_00959 366602.Caul_2706 5.4e-62 244.6 Caulobacterales ko:K07058 ko00000 Bacteria 1MXQA@1224,2KGZ8@204458,2TSFP@28211,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB MAG.T12.39_00960 450851.PHZ_c1616 5.5e-190 670.2 Caulobacterales 5.1.99.4 ko:K01796 ko00120,ko01100,ko04146,map00120,map01100,map04146 M00104 R08734,R08739 RC02345 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW1H@1224,2KFRK@204458,2TR7D@28211,COG1804@1,COG1804@2 NA|NA|NA C PFAM L-carnitine dehydratase bile acid-inducible protein F MAG.T12.39_00961 450851.PHZ_c1617 5.9e-95 354.0 Caulobacterales Bacteria 1MXWI@1224,2KGAY@204458,2TQQ6@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_00962 69395.JQLZ01000005_gene3794 2.1e-140 505.8 Caulobacterales actA ko:K13591,ko:K21025 ko02025,ko04112,map02025,map04112 M00511 ko00000,ko00001,ko00002,ko02022 Bacteria 1R56G@1224,2KF1Q@204458,2TTWV@28211,COG2199@1,COG3706@2 NA|NA|NA T Diguanylate cyclase MAG.T12.39_00963 450851.PHZ_c1619 0.0 1768.4 Caulobacterales mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUXG@1224,2KF5C@204458,2TR2H@28211,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site MAG.T12.39_00964 1382303.JPOM01000001_gene1222 1.9e-22 111.7 Caulobacterales sdhE GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 ko:K00240,ko:K09159 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 1N6SJ@1224,2KH5Y@204458,2UFF5@28211,COG2938@1,COG2938@2 NA|NA|NA S Flavinator of succinate dehydrogenase MAG.T12.39_00965 450851.PHZ_c1621 4.1e-260 904.0 Caulobacterales recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWN2@1224,2KFQP@204458,2TR86@28211,COG1200@1,COG1200@2 NA|NA|NA L ATP-dependent DNA helicase RecG MAG.T12.39_00966 450851.PHZ_c1623 1.6e-107 396.4 Caulobacterales pla GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 Bacteria 1MVDA@1224,2KEZS@204458,2TUDQ@28211,COG2267@1,COG2267@2 NA|NA|NA I Protein of unknown function (DUF3089) MAG.T12.39_00967 450851.PHZ_c1624 8.4e-150 536.6 Caulobacterales hldD 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MVE4@1224,2KF1V@204458,2TQJI@28211,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose MAG.T12.39_00968 450851.PHZ_c1625 2.7e-197 694.9 Caulobacterales hldE 2.7.1.167,2.7.7.70 ko:K03272,ko:K21344 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MV3Z@1224,2KFUY@204458,2TU12@28211,COG0615@1,COG0615@2,COG2870@1,COG2870@2 NA|NA|NA H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose MAG.T12.39_00969 1382303.JPOM01000001_gene1609 5.2e-124 450.7 Caulobacterales kdsA 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MV91@1224,2KFPM@204458,2TRJX@28211,COG2877@1,COG2877@2 NA|NA|NA M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase MAG.T12.39_00970 366602.Caul_2920 2e-156 558.9 Caulobacterales cfa GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1MX3U@1224,2KG6J@204458,2TR8K@28211,COG2230@1,COG2230@2 NA|NA|NA M Cyclopropane-fatty-acyl-phospholipid synthase MAG.T12.39_00971 1449049.JONW01000009_gene4441 1.3e-155 555.8 Caulobacterales cysB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUBE@1224,2KFMQ@204458,2TR4W@28211,COG0031@1,COG0031@2 NA|NA|NA E Cysteine synthase MAG.T12.39_00972 588932.JHOF01000018_gene794 2.5e-86 325.5 Caulobacterales sseA GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2,4.4.1.8 ko:K01011,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01120,ko01230,ko04122,map00270,map00450,map00920,map01100,map01110,map01120,map01230,map04122 M00017 R00782,R01286,R01931,R02408,R03105,R03106,R04941 RC00056,RC00069,RC00214,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 iECs_1301.ECs3387,iZ_1308.Z3788 Bacteria 1MW4B@1224,2KFH2@204458,2TR9R@28211,COG2897@1,COG2897@2 NA|NA|NA P Sulfurtransferase MAG.T12.39_00973 1292034.OR37_00388 6.8e-135 487.3 Caulobacterales metC 4.4.1.11,4.4.1.8 ko:K01760,ko:K01761 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00654,R00782,R01286,R02408,R04770,R04941 RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9E@1224,2KF9X@204458,2TS8Z@28211,COG0626@1,COG0626@2 NA|NA|NA E cystathionine beta-lyase MAG.T12.39_00974 450851.PHZ_c2066 5.1e-133 481.1 Caulobacterales cpg2_2 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 1MUSU@1224,2KK50@204458,2TTBP@28211,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T12.39_00975 402881.Plav_0092 2e-189 668.7 Alphaproteobacteria 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,2TQR1@28211,COG1012@1,COG1012@2 NA|NA|NA C belongs to the aldehyde dehydrogenase family MAG.T12.39_00976 247633.GP2143_13086 2.2e-21 109.0 Proteobacteria Bacteria 1NBAI@1224,2FIXR@1,312JV@2 NA|NA|NA S Cytochrome C' MAG.T12.39_00978 190650.CC_1389 4.1e-39 167.2 Caulobacterales MA20_30235 1.6.5.3 ko:K00329 ko00190,map00190 R11945 RC00061 ko00000,ko00001,ko01000 Bacteria 1MZK8@1224,2C7TH@1,2KGYS@204458,2UC2R@28211,32RJS@2 NA|NA|NA S ETC complex I subunit MAG.T12.39_00980 1382303.JPOM01000001_gene1158 3.9e-38 164.5 Caulobacterales Bacteria 1RJ7W@1224,2KJ2E@204458,2UAFZ@28211,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T12.39_00981 450851.PHZ_c1638 7e-41 173.7 Caulobacterales ko:K09005 ko00000 Bacteria 1MZBJ@1224,2KH17@204458,2UBSI@28211,COG1430@1,COG1430@2 NA|NA|NA S Uncharacterized ACR, COG1430 MAG.T12.39_00982 69395.JQLZ01000007_gene1640 7e-62 243.8 Caulobacterales cspB ko:K03704 ko00000,ko03000 Bacteria 1RAUE@1224,2KGHD@204458,2U0S7@28211,COG1278@1,COG1278@2 NA|NA|NA K DNA-binding MAG.T12.39_00983 420324.KI911956_gene3658 4.2e-95 355.1 Methylobacteriaceae Bacteria 1JRCZ@119045,1MU23@1224,2TS2G@28211,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T12.39_00987 716544.wcw_0673 2e-66 260.0 Chlamydiae 2.7.1.121 ko:K05878,ko:K06919,ko:K07497 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 Bacteria 2JH13@204428,COG0467@1,COG0467@2,COG2390@1,COG2390@2,COG4643@1,COG4643@2 NA|NA|NA T Transcriptional regulator MAG.T12.39_00988 1380367.JIBC01000005_gene3397 3.9e-35 154.5 Sulfitobacter Bacteria 1N8E5@1224,2E5FX@1,2UAZZ@28211,3307M@2,3ZZ17@60136 NA|NA|NA MAG.T12.39_00992 414684.RC1_0055 6.2e-271 940.6 Rhodospirillales frlR ko:K03593,ko:K03710 ko00000,ko03000,ko03029,ko03036 Bacteria 1NRCT@1224,2JVSC@204441,2UPBF@28211,COG0489@1,COG0489@2,COG2188@1,COG2188@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_00993 272568.GDI0754 1.8e-77 295.8 Rhodospirillales Bacteria 1NZ9X@1224,2CCG6@1,2JX9Q@204441,2UTBX@28211,3406N@2 NA|NA|NA MAG.T12.39_00995 575586.HMPREF0016_00851 1.1e-55 223.4 Moraxellaceae Bacteria 1RD0D@1224,1S05E@1236,29E11@1,300Z0@2,3NNB9@468 NA|NA|NA MAG.T12.39_00996 391600.ABRU01000060_gene1470 2.6e-14 84.0 Alphaproteobacteria ko:K07483,ko:K07497 ko00000 Bacteria 1MZ3D@1224,2UBSS@28211,COG2963@1,COG2963@2 NA|NA|NA L COG2801 Transposase and inactivated derivatives MAG.T12.39_00997 156889.Mmc1_0802 7.9e-172 610.5 Alphaproteobacteria ko:K02471,ko:K09384 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.203.11,3.A.1.203.4 Bacteria 1PRQ3@1224,2U2KB@28211,COG3410@1,COG3410@2,COG4178@1,COG4178@2 NA|NA|NA S Uncharacterized conserved protein (DUF2075) MAG.T12.39_00998 1449049.JONW01000005_gene1057 2.8e-30 138.3 Alphaproteobacteria Bacteria 1RKGP@1224,2DB8C@1,2UAT8@28211,2Z7R9@2 NA|NA|NA MAG.T12.39_01000 450851.PHZ_c1640 1.2e-231 809.3 Caulobacterales recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU1M@1224,2KFDH@204458,2TRZQ@28211,COG0608@1,COG0608@2 NA|NA|NA L single-stranded-DNA-specific exonuclease RecJ MAG.T12.39_01001 450851.PHZ_c1642 4.8e-147 527.3 Caulobacterales glpX 3.1.3.11,3.1.3.37 ko:K02446,ko:K11532 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUB1@1224,2KF57@204458,2TSPE@28211,COG1494@1,COG1494@2 NA|NA|NA G fructose-1,6-bisphosphatase MAG.T12.39_01002 450851.PHZ_c1643 8.3e-174 616.7 Caulobacterales hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1MUDC@1224,2KFNT@204458,2TQWS@28211,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase MAG.T12.39_01003 450851.PHZ_c1644 1.1e-212 745.7 Caulobacterales yfdZ GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 iEcSMS35_1347.EcSMS35_2531,iSBO_1134.SBO_2405 Bacteria 1MWS8@1224,2KFVH@204458,2TRE3@28211,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase MAG.T12.39_01004 450851.PHZ_c1645 9.8e-09 66.6 Caulobacterales Bacteria 1NIU0@1224,2ENFQ@1,2KHIS@204458,2UKJV@28211,33G33@2 NA|NA|NA MAG.T12.39_01005 450851.PHZ_c1646 1.3e-263 915.6 Caulobacterales phbC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03821 ko00650,map00650 R04254 RC00004 ko00000,ko00001,ko01000 Bacteria 1MU68@1224,2KF79@204458,2TR7S@28211,COG3243@1,COG3243@2 NA|NA|NA I poly(R)-hydroxyalkanoic acid synthase MAG.T12.39_01006 69395.JQLZ01000004_gene714 6.4e-13 81.6 Proteobacteria Bacteria 1RGUR@1224,2B64P@1,31Z1K@2 NA|NA|NA MAG.T12.39_01007 450851.PHZ_c1650 1e-55 223.0 Caulobacterales msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 1RGWC@1224,2KGND@204458,2U70T@28211,COG0229@1,COG0229@2 NA|NA|NA O SelR domain MAG.T12.39_01008 450851.PHZ_c1651 8.5e-131 473.4 Caulobacterales argC 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVJ6@1224,2KFA4@204458,2TRMT@28211,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde MAG.T12.39_01009 59538.XP_005969848.1 5.6e-67 260.4 Opisthokonta MRPS9 GO:0000313,GO:0000314,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0030490,GO:0031974,GO:0032543,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0098798,GO:0140053,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Opisthokonta 39SD3@33154,COG0103@1,KOG1697@2759 NA|NA|NA J structural constituent of ribosome MAG.T12.39_01010 1382303.JPOM01000001_gene1133 2.1e-74 285.0 Caulobacterales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RA11@1224,2KG9U@204458,2U5FM@28211,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly MAG.T12.39_01011 190650.CC_1374 1.3e-113 416.4 Caulobacterales ctaA ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 Bacteria 1MVJ4@1224,2KF6F@204458,2TR0M@28211,COG1612@1,COG1612@2 NA|NA|NA O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group MAG.T12.39_01012 366602.Caul_3030 9.4e-13 79.0 Alphaproteobacteria Bacteria 1NK5B@1224,2A9VG@1,2UMVQ@28211,30Z3C@2 NA|NA|NA S Protein of unknown function (DUF2842) MAG.T12.39_01014 1292034.OR37_03818 5.2e-30 137.5 Caulobacterales merR ko:K11923,ko:K22491 ko00000,ko03000 Bacteria 1RGYB@1224,2KGRA@204458,2U9A5@28211,COG0789@1,COG0789@2 NA|NA|NA K PFAM regulatory protein MerR MAG.T12.39_01015 450851.PHZ_c1658 1.9e-41 174.9 Caulobacterales himA ko:K04764 ko00000,ko03032,ko03036,ko03400 Bacteria 1RH5Z@1224,2KH01@204458,2UCDG@28211,COG0776@1,COG0776@2 NA|NA|NA K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control MAG.T12.39_01016 450851.PHZ_c1659 2.9e-147 528.1 Caulobacterales fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MU9N@1224,2KFJQ@204458,2TR60@28211,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T12.39_01017 450851.PHZ_c1660 5.2e-107 394.4 Caulobacterales plsX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695 Bacteria 1MVM3@1224,2KF5R@204458,2TR53@28211,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA MAG.T12.39_01018 450851.PHZ_c1661 2.7e-46 191.8 Caulobacterales yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1PT3A@1224,2KGXK@204458,2V51T@28211,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 MAG.T12.39_01019 450851.PHZ_c1662 1e-50 206.5 Caulobacterales ko:K17662 ko00000,ko03029 Bacteria 1N12T@1224,2KGSB@204458,2UCES@28211,COG5452@1,COG5452@2 NA|NA|NA S Ubiquinol-cytochrome C chaperone MAG.T12.39_01020 450851.PHZ_c1663 9.9e-56 223.0 Caulobacterales MA20_36760 Bacteria 1RHYM@1224,2KGSR@204458,2UBU9@28211,COG2913@1,COG2913@2 NA|NA|NA J PFAM SmpA OmlA MAG.T12.39_01021 450851.PHZ_c1664 2.5e-297 1027.7 Caulobacterales hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 1MUQ3@1224,2KFAX@204458,2TR9G@28211,COG3808@1,COG3808@2 NA|NA|NA C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force MAG.T12.39_01022 69395.JQLZ01000007_gene1614 8.2e-15 87.0 Caulobacterales Bacteria 1N7K9@1224,2E4AU@1,2KH9M@204458,2UFGR@28211,32Z6H@2 NA|NA|NA MAG.T12.39_01023 450851.PHZ_c1667 1.1e-77 297.0 Caulobacterales thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iSFV_1184.SFV_0382,iYO844.BSU05900 Bacteria 1MU9X@1224,2KF23@204458,2TTI6@28211,COG0611@1,COG0611@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 MAG.T12.39_01024 450851.PHZ_c1668 1.4e-54 219.2 Caulobacterales nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03625 ko00000,ko03009,ko03021 Bacteria 1RHFZ@1224,2KGQ3@204458,2UBQA@28211,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons MAG.T12.39_01025 450851.PHZ_c1669 5.6e-56 223.8 Caulobacterales ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 Bacteria 1RD9J@1224,2KGV0@204458,2U9IZ@28211,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin MAG.T12.39_01026 450851.PHZ_c1670 2.4e-88 331.6 Caulobacterales ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 1MUMB@1224,2KGE4@204458,2U3RS@28211,COG0307@1,COG0307@2 NA|NA|NA H Riboflavin synthase MAG.T12.39_01027 573065.Astex_2941 1.6e-56 226.1 Caulobacterales ribD 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 Bacteria 1N4VZ@1224,2KGTP@204458,2TXAC@28211,COG1985@1,COG1985@2 NA|NA|NA H RibD C-terminal domain MAG.T12.39_01028 450851.PHZ_c1674 2.5e-67 261.5 Caulobacterales nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1RE7V@1224,2KG9K@204458,2U75W@28211,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes MAG.T12.39_01029 1459636.NTE_01021 6.9e-15 87.4 Thaumarchaeota degP Archaea 41S9W@651137,COG0265@1,arCOG02833@2157 NA|NA|NA O Trypsin-like serine protease with C-terminal PDZ domain MAG.T12.39_01030 450851.PHZ_c3165 1.9e-264 918.3 Caulobacterales mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1MV61@1224,2KF4S@204458,2TR2M@28211,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex MAG.T12.39_01031 450851.PHZ_c3164 6.8e-81 307.8 Caulobacterales gumN ko:K09973 ko00000 Bacteria 1N8WD@1224,2KH5Z@204458,2UG39@28211,COG3735@1,COG3735@2 NA|NA|NA S PFAM GumN family protein MAG.T12.39_01032 1449049.JONW01000005_gene1109 3.7e-62 244.6 Caulobacterales Bacteria 1REH5@1224,2C068@1,2KGMP@204458,2U74G@28211,30N9J@2 NA|NA|NA S Protein of unknown function (DUF3035) MAG.T12.39_01033 450851.PHZ_c3162 3.9e-44 184.5 Caulobacterales lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1RGV9@1224,2KGYP@204458,2UBUC@28211,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins MAG.T12.39_01034 450851.PHZ_c3161 0.0 1632.1 Caulobacterales ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1MVBQ@1224,2KFIV@204458,2TR3N@28211,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) MAG.T12.39_01035 983920.Y88_3378 1.2e-39 169.5 Sphingomonadales doc ko:K07341 ko00000,ko02048 Bacteria 1N1FW@1224,2K6NP@204457,2U8GF@28211,COG3654@1,COG3654@2 NA|NA|NA S Fic/DOC family MAG.T12.39_01036 1522072.IL54_3521 4e-23 113.6 Sphingomonadales ko:K07172,ko:K18842 ko00000,ko02048 Bacteria 1N7UD@1224,2K74A@204457,2UFHF@28211,COG2336@1,COG2336@2 NA|NA|NA T SpoVT / AbrB like domain MAG.T12.39_01037 450851.PHZ_c3160 8.9e-117 426.8 Caulobacterales ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV9I@1224,2KEXY@204458,2TTUY@28211,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family MAG.T12.39_01038 450851.PHZ_c3159 6.7e-48 196.8 Caulobacterales phaJ1 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWPK@1224,2KGS2@204458,2U5CQ@28211,COG2030@1,COG2030@2 NA|NA|NA I dehydratase MAG.T12.39_01039 450851.PHZ_c3158 1.3e-96 359.8 Caulobacterales MA20_05625 Bacteria 1MU9Y@1224,2KF3K@204458,2TUH0@28211,COG0647@1,COG0647@2 NA|NA|NA G Hydrolase MAG.T12.39_01040 190650.CC_0710 8.4e-139 500.4 Caulobacterales MA20_05620 ko:K13593 ko04112,map04112 ko00000,ko00001 Bacteria 1MU4F@1224,2KF0R@204458,2TU9M@28211,COG2200@1,COG2200@2 NA|NA|NA T Diguanylate phosphodiesterase MAG.T12.39_01041 450851.PHZ_c3152 1.9e-134 485.3 Caulobacterales mmgB 1.1.1.157,1.1.1.35 ko:K00074,ko:K07516 ko00071,ko00360,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00360,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R01976,R04737,R04739,R04741,R04743,R04745,R04748,R05305,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9P@1224,2KFRN@204458,2TR8E@28211,COG1250@1,COG1250@2 NA|NA|NA I Dehydrogenase MAG.T12.39_01042 450851.PHZ_c3151 3.2e-127 461.5 Caulobacterales etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 ko:K03522 ko00000,ko04147 Bacteria 1MUFI@1224,2KF00@204458,2TR10@28211,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein MAG.T12.39_01043 450851.PHZ_c3150 1.8e-109 402.1 Caulobacterales etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K03521 ko00000 Bacteria 1MVH6@1224,2KF0K@204458,2TR4J@28211,COG2086@1,COG2086@2 NA|NA|NA C Electron transfer flavoprotein MAG.T12.39_01044 1121123.AUAO01000002_gene68 5.8e-08 63.5 Caulobacterales Bacteria 1NQ6P@1224,2DSTQ@1,2KHH8@204458,2UN5U@28211,33HDI@2 NA|NA|NA MAG.T12.39_01045 450851.PHZ_c3149 4.4e-63 247.7 Caulobacterales yvqK 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDUF@1224,2KGCW@204458,2U5J1@28211,COG2096@1,COG2096@2 NA|NA|NA S adenosyltransferase MAG.T12.39_01046 69395.JQLZ01000001_gene3399 4.2e-16 90.1 Caulobacterales MA20_20545 Bacteria 1NH9E@1224,2C8F7@1,2KHJ3@204458,2UJFC@28211,33A2N@2 NA|NA|NA S Hypoxia induced protein conserved region MAG.T12.39_01047 450851.PHZ_c3145 1.6e-225 788.9 Caulobacterales mcd 1.3.8.12 ko:K14448 ko00630,ko01120,ko01200,map00630,map01120,map01200 M00373 R09293 RC02483 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUDR@1224,2KFKX@204458,2TR78@28211,COG1960@1,COG1960@2 NA|NA|NA C acyl-CoA dehydrogenase MAG.T12.39_01048 450851.PHZ_c3144 2.6e-80 305.1 Caulobacterales 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1MXHH@1224,2KFYF@204458,2TVGY@28211,COG0625@1,COG0625@2 NA|NA|NA O Belongs to the GST superfamily MAG.T12.39_01049 1479238.JQMZ01000001_gene2481 5.1e-238 830.9 Hyphomonadaceae Bacteria 1MWRH@1224,2TSWZ@28211,43X9K@69657,COG1002@1,COG1002@2 NA|NA|NA V COG1002 Type II restriction enzyme, methylase subunits MAG.T12.39_01050 450851.PHZ_c3143 2.8e-79 302.0 Alphaproteobacteria Bacteria 1QY19@1224,2TXFD@28211,COG1073@1,COG1073@2 NA|NA|NA S PFAM alpha beta hydrolase fold MAG.T12.39_01051 59538.XP_005975964.1 2.5e-72 278.5 Vertebrata Metazoa 38PE0@33154,3BEPT@33208,3CVZ0@33213,47ZUG@7711,49730@7742,COG0740@1,KOG0840@2759 NA|NA|NA O serine-type endopeptidase activity MAG.T12.39_01052 450851.PHZ_c3135 3.9e-115 421.0 Caulobacterales Bacteria 1MWGC@1224,2KFQE@204458,2TSNX@28211,COG1028@1,COG1028@2 NA|NA|NA IQ short-chain dehydrogenase reductase MAG.T12.39_01053 450851.PHZ_c3134 5.6e-153 547.4 Caulobacterales ybdL GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.6.1.17,2.6.1.88 ko:K14267,ko:K14287 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475,R08618 RC00006,RC00025 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0858c Bacteria 1MW0Z@1224,2KFCV@204458,2TTGJ@28211,COG0436@1,COG0436@2 NA|NA|NA E aminotransferase class I and II MAG.T12.39_01054 1382303.JPOM01000001_gene1706 0.0 1096.6 Caulobacterales typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1MV5Q@1224,2KFB4@204458,2TR63@28211,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA MAG.T12.39_01055 1449049.JONW01000008_gene705 1e-82 313.5 Caulobacterales MA20_06380 3.5.1.68 ko:K01458 ko00340,ko00630,map00340,map00630 R00525 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1MY4D@1224,2KGJA@204458,2TUPZ@28211,COG3741@1,COG3741@2 NA|NA|NA E PFAM N-formylglutamate amidohydrolase MAG.T12.39_01056 450851.PHZ_c3129 1.4e-46 192.2 Caulobacterales Bacteria 1QUSA@1224,2KGTS@204458,2TW5G@28211,COG0745@1,COG0745@2 NA|NA|NA T Response regulator receiver MAG.T12.39_01058 450851.PHZ_c1184 1.2e-109 403.3 Caulobacterales selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K06917 ko00000,ko01000,ko03016 Bacteria 1N4T5@1224,2KHTI@204458,2TS2E@28211,COG2603@1,COG2603@2 NA|NA|NA H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA MAG.T12.39_01059 1121124.JNIX01000013_gene1639 5.8e-133 480.7 Caulobacterales selD 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 Bacteria 1MWFG@1224,2KFVK@204458,2TR91@28211,COG0709@1,COG0709@2 NA|NA|NA E AIR synthase related protein, C-terminal domain MAG.T12.39_01060 745310.G432_16785 6.5e-64 250.8 Sphingomonadales 3.6.3.20,3.6.3.29 ko:K02017,ko:K05816 ko02010,map02010 M00189,M00198 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.3,3.A.1.8 Bacteria 1RC3N@1224,2KENM@204457,2TY58@28211,COG3842@1,COG3842@2 NA|NA|NA E ABC transporter MAG.T12.39_01061 745310.G432_16790 5.2e-71 274.2 Sphingomonadales modB ko:K02018,ko:K15496 ko02010,map02010 M00189,M00423 ko00000,ko00001,ko00002,ko02000 3.A.1.6.5,3.A.1.8 Bacteria 1MUXR@1224,2K0AD@204457,2TSYJ@28211,COG4149@1,COG4149@2 NA|NA|NA P Molybdate MAG.T12.39_01062 745310.G432_16795 8.3e-52 210.7 Sphingomonadales modA ko:K02020 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria 1MVNA@1224,2K17W@204457,2U5B1@28211,COG0725@1,COG0725@2 NA|NA|NA P Molybdenum ABC transporter MAG.T12.39_01063 450851.PHZ_c3127 1e-196 694.1 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MU9K@1224,2KEZ7@204458,2TS65@28211,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T12.39_01064 69395.JQLZ01000001_gene3239 1.9e-18 99.0 Caulobacterales Bacteria 1NCA5@1224,2ED0I@1,2KHB2@204458,2UI1T@28211,336XI@2 NA|NA|NA MAG.T12.39_01065 366602.Caul_0866 2.6e-170 605.5 Caulobacterales mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 ko:K00773,ko:K07319,ko:K11782,ko:K15461 ko00130,ko01110,map00130,map01110 R00601,R03789,R08702,R10209,R10666 RC00003,RC00053,RC00060,RC00063,RC01483,RC03232 ko00000,ko00001,ko01000,ko02048,ko03016 Bacteria 1MZW5@1224,2KF4F@204458,2TUNX@28211,COG0665@1,COG0665@2,COG4121@1,COG4121@2 NA|NA|NA J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 MAG.T12.39_01066 450851.PHZ_c3326 1.9e-79 302.8 Caulobacterales Bacteria 1QTTM@1224,2KK8U@204458,2TXW1@28211,COG0596@1,COG0596@2 NA|NA|NA S Serine aminopeptidase, S33 MAG.T12.39_01067 450851.PHZ_c3325 3.1e-82 312.0 Caulobacterales ko:K07107 ko00000,ko01000 Bacteria 1RA27@1224,2KGH7@204458,2U6W6@28211,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T12.39_01068 450851.PHZ_c3324 2.4e-37 162.2 Caulobacterales ko:K03620 ko02020,map02020 ko00000,ko00001 Bacteria 1MX97@1224,2KGHG@204458,2U0ZF@28211,COG2864@1,COG2864@2,COG4117@1,COG4117@2 NA|NA|NA C Prokaryotic cytochrome b561 MAG.T12.39_01069 450851.PHZ_c3323 9.2e-88 330.1 Caulobacterales ko:K07147 ko00000,ko01000 Bacteria 1MUW0@1224,2KGY8@204458,2TS40@28211,COG2041@1,COG2041@2 NA|NA|NA S Oxidoreductase molybdopterin binding domain MAG.T12.39_01070 450851.PHZ_c3320 1.7e-180 638.6 Caulobacterales GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 ko:K00809 ko00000,ko01000 Bacteria 1MVC6@1224,2KFV1@204458,2TTRW@28211,COG1899@1,COG1899@2 NA|NA|NA O Belongs to the deoxyhypusine synthase family MAG.T12.39_01071 450851.PHZ_c3319 6.3e-180 637.1 Caulobacterales ldc 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1MZ7Y@1224,2KEZ5@204458,2TSKB@28211,COG0019@1,COG0019@2 NA|NA|NA E decarboxylase MAG.T12.39_01072 1449049.JONW01000006_gene2991 9.1e-115 419.9 Caulobacterales phnC 3.6.3.28 ko:K02041 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1MVE9@1224,2KFZF@204458,2TRR3@28211,COG3638@1,COG3638@2 NA|NA|NA P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system MAG.T12.39_01073 1292034.OR37_02019 3e-105 388.7 Caulobacterales ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1MXD8@1224,2KG73@204458,2TQMQ@28211,COG3221@1,COG3221@2 NA|NA|NA P phosphonate ABC transporter, periplasmic MAG.T12.39_01074 450851.PHZ_c3316 1.3e-100 372.9 Caulobacterales phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1MW4F@1224,2KF3M@204458,2TTXJ@28211,COG3639@1,COG3639@2 NA|NA|NA P ABC transporter MAG.T12.39_01075 1449049.JONW01000006_gene2994 4.6e-57 228.8 Caulobacterales oprP ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 1RA39@1224,2KIBB@204458,2U9KD@28211,COG3746@1,COG3746@2 NA|NA|NA P PFAM phosphate-selective porin O and P MAG.T12.39_01076 1449049.JONW01000006_gene2995 1.4e-139 502.7 Caulobacterales ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MUH9@1224,2KFPD@204458,2TR1C@28211,COG0226@1,COG0226@2 NA|NA|NA P PBP superfamily domain MAG.T12.39_01077 450851.PHZ_c3311 7.3e-176 623.6 Caulobacterales gtrA Bacteria 1MUB7@1224,2KFKC@204458,2TQQ0@28211,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 MAG.T12.39_01078 1382303.JPOM01000001_gene870 1.1e-112 412.9 Caulobacterales lpxH_2 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MVKD@1224,2KG89@204458,2TSEB@28211,COG2908@1,COG2908@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain MAG.T12.39_01079 1292034.OR37_02017 0.0 1154.8 Alphaproteobacteria Bacteria 1QTXJ@1224,2UNSU@28211,COG4773@1,COG4773@2 NA|NA|NA P PFAM TonB dependent receptor, TonB-dependent Receptor Plug Domain MAG.T12.39_01080 1449049.JONW01000006_gene3016 2.4e-41 175.6 Caulobacterales GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 Bacteria 1RI3V@1224,2KGWG@204458,2UAJ5@28211,COG1309@1,COG1309@2 NA|NA|NA K tetR family MAG.T12.39_01081 450851.PHZ_c3307 5.9e-207 727.2 Caulobacterales Bacteria 1MUBX@1224,2KEYU@204458,2TSQN@28211,COG4805@1,COG4805@2 NA|NA|NA S Bacterial protein of unknown function (DUF885) MAG.T12.39_01082 450851.PHZ_c3306 2.2e-159 568.9 Caulobacterales atrC1 ko:K03294 ko00000 2.A.3.2 Bacteria 1MXNJ@1224,2KG4Y@204458,2TRNX@28211,COG0531@1,COG0531@2 NA|NA|NA E amino acid MAG.T12.39_01083 1502851.FG93_00950 1.4e-48 199.5 Alphaproteobacteria ko:K07025 ko00000 Bacteria 1RKHU@1224,2UANU@28211,COG1011@1,COG1011@2 NA|NA|NA S Hydrolase MAG.T12.39_01084 1121124.JNIX01000010_gene852 2.2e-73 282.3 Caulobacterales 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028 ko02010,map02010 M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 1MUNG@1224,2KHNM@204458,2U7KQ@28211,COG1120@1,COG1120@2 NA|NA|NA HP ATPases associated with a variety of cellular activities MAG.T12.39_01085 1112212.JH584235_gene1151 1.3e-94 353.2 Sphingomonadales btuC ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1MV9W@1224,2K0DB@204457,2TR9A@28211,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily MAG.T12.39_01086 1292034.OR37_00332 2.5e-57 229.2 Caulobacterales ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1RAUP@1224,2KIH1@204458,2TUB0@28211,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein MAG.T12.39_01087 1449049.JONW01000013_gene4670 6.3e-130 471.5 Caulobacterales btuB ko:K02014,ko:K16092 ko00000,ko02000 1.B.14,1.B.14.3 Bacteria 1MW63@1224,2KFJZ@204458,2TT3G@28211,COG4206@1,COG4206@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T12.39_01088 450851.PHZ_c0558 1.3e-211 742.7 Caulobacterales acd 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU20@1224,2KFI7@204458,2TQJS@28211,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T12.39_01089 1500893.JQNB01000001_gene2819 1.1e-118 433.3 Xanthomonadales attH Bacteria 1MUVF@1224,1RZ65@1236,1XAMK@135614,COG5621@1,COG5621@2 NA|NA|NA S Lipocalin-like domain MAG.T12.39_01090 1248916.ANFY01000008_gene2089 1.4e-188 666.8 Sphingomonadales salY ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MVCT@1224,2K0UA@204457,2TSPH@28211,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T12.39_01091 1500893.JQNB01000001_gene2821 1.7e-69 269.2 Xanthomonadales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1NCFC@1224,1S2JJ@1236,1XCER@135614,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T12.39_01092 450851.PHZ_c2912 2.4e-136 491.9 Caulobacterales cuyA GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0034011,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.4.1.15,4.4.1.25 ko:K05396,ko:K17950 ko00270,map00270 R01874,R07634 RC00382,RC01784 ko00000,ko00001,ko01000 Bacteria 1MVYF@1224,2KF4J@204458,2TRCB@28211,COG2515@1,COG2515@2 NA|NA|NA E TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family MAG.T12.39_01093 450851.PHZ_c2913 3.6e-75 288.1 Caulobacterales 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1MV03@1224,2KGMR@204458,2U86Y@28211,COG1794@1,COG1794@2 NA|NA|NA M Belongs to the aspartate glutamate racemases family MAG.T12.39_01094 450851.PHZ_c2911 5e-21 107.5 Alphaproteobacteria Bacteria 1NCA5@1224,2ED0I@1,2UI1T@28211,336XI@2 NA|NA|NA MAG.T12.39_01095 1449049.JONW01000008_gene681 3.6e-252 877.5 Caulobacterales pepF ko:K08602 ko00000,ko01000,ko01002 Bacteria 1MXAC@1224,2KFPQ@204458,2TRPY@28211,COG1164@1,COG1164@2 NA|NA|NA E Oligoendopeptidase, pepF M3 family MAG.T12.39_01096 450851.PHZ_c1859 2.4e-123 449.1 Caulobacterales Bacteria 1MXQX@1224,2KG0S@204458,2U1V8@28211,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T12.39_01097 450851.PHZ_c1858 4.7e-178 630.9 Caulobacterales Bacteria 1MXXR@1224,2KFWI@204458,2TUMS@28211,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T12.39_01098 69395.JQLZ01000006_gene2309 1.6e-47 195.7 Caulobacterales ko:K02614 ko00360,map00360 R09840 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1RJ7W@1224,2KJ2E@204458,2UAFZ@28211,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T12.39_01099 450851.PHZ_c3105 1.1e-118 433.3 Caulobacterales ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1R9GQ@1224,2KGD4@204458,2U3YF@28211,COG2267@1,COG2267@2 NA|NA|NA I PFAM alpha beta hydrolase MAG.T12.39_01100 509190.Cseg_0617 1.2e-19 102.1 Caulobacterales Bacteria 1NHS7@1224,2EJ8V@1,2KHHZ@204458,2UNAD@28211,33D02@2 NA|NA|NA S aa3 type cytochrome c oxidase subunit IV MAG.T12.39_01101 366602.Caul_0891 4.7e-149 534.3 Caulobacterales pntAA GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1MVXU@1224,2KFZQ@204458,2TSZN@28211,COG3288@1,COG3288@2 NA|NA|NA C NADP transhydrogenase subunit alpha MAG.T12.39_01102 69395.JQLZ01000006_gene2314 1e-35 156.0 Caulobacterales pntAB GO:0008150,GO:0008152,GO:0055114 1.6.1.1,1.6.1.2 ko:K00322,ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1MZ3E@1224,2KGR0@204458,2UBXS@28211,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch MAG.T12.39_01103 190650.CC_3303 3.6e-223 780.8 Caulobacterales pntB GO:0008150,GO:0008152,GO:0055114 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1MUP4@1224,2KFJ5@204458,2TQN1@28211,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane MAG.T12.39_01105 450851.PHZ_c3096 1.2e-70 273.5 Bacteria Bacteria COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity MAG.T12.39_01106 450851.PHZ_c3095 4.4e-95 355.1 Caulobacterales tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1MU85@1224,2KGAD@204458,2TRK1@28211,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine MAG.T12.39_01107 190650.CC_3228 1.9e-18 99.8 Caulobacterales cpoB Bacteria 1MUSV@1224,2KH3Q@204458,2U6ZQ@28211,COG1729@1,COG1729@2 NA|NA|NA D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division MAG.T12.39_01108 450851.PHZ_c3093 1.2e-47 196.4 Caulobacterales pal ko:K03640 ko00000,ko02000 2.C.1.2 Bacteria 1MZTV@1224,2KGKV@204458,2U758@28211,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T12.39_01109 450851.PHZ_c3092 3.9e-99 368.6 Caulobacterales tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 1MV09@1224,2KEY1@204458,2TR03@28211,COG0823@1,COG0823@2 NA|NA|NA U Involved in the TonB-independent uptake of proteins MAG.T12.39_01110 366602.Caul_4428 1.6e-22 113.6 Proteobacteria Bacteria 1N5K2@1224,COG5373@1,COG5373@2 NA|NA|NA S membrane MAG.T12.39_01111 450851.PHZ_c3090 4.9e-45 187.6 Caulobacterales tolR ko:K03559,ko:K03560 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1MZ6M@1224,2KGV5@204458,2UA46@28211,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR MAG.T12.39_01112 450851.PHZ_c3089 3.6e-83 314.7 Caulobacterales tolQ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1NCWW@1224,2KFKH@204458,2TQXQ@28211,COG0811@1,COG0811@2 NA|NA|NA U MotA TolQ ExbB proton channel MAG.T12.39_01113 1449049.JONW01000002_gene2503 3.2e-48 198.0 Caulobacterales ybgC ko:K07107 ko00000,ko01000 Bacteria 1MZH6@1224,2KGYJ@204458,2UBYM@28211,COG0824@1,COG0824@2 NA|NA|NA S Tol-pal system-associated acyl-CoA thioesterase MAG.T12.39_01114 450851.PHZ_c3087 7.4e-149 533.5 Caulobacterales ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU38@1224,2KEYJ@204458,2TQNG@28211,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing MAG.T12.39_01115 1121123.AUAO01000001_gene1061 5e-60 237.7 Caulobacterales ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWJR@1224,2KG8V@204458,2TSKM@28211,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB MAG.T12.39_01116 1292034.OR37_00892 7.6e-51 206.8 Caulobacterales ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUJI@1224,2KGKN@204458,2U70Z@28211,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group MAG.T12.39_01117 69395.JQLZ01000001_gene3367 2.4e-285 988.4 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MU9K@1224,2KG7W@204458,2U0AK@28211,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P TonB-dependent receptor MAG.T12.39_01118 1123240.ATVO01000006_gene1288 6e-57 227.6 Sphingomonadales coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1MV3M@1224,2K64V@204457,2TS7E@28211,COG1072@1,COG1072@2 NA|NA|NA H Phosphoribulokinase / Uridine kinase family MAG.T12.39_01119 450851.PHZ_c3084 3.2e-61 241.9 Caulobacterales rip2 Bacteria 1NSFF@1224,2KGPG@204458,2TRIF@28211,COG1994@1,COG1994@2 NA|NA|NA S Peptidase M50 MAG.T12.39_01120 450851.PHZ_c3068 3.8e-99 367.9 Caulobacterales yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 1MW3X@1224,2KFPC@204458,2TRSK@28211,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein MAG.T12.39_01121 450851.PHZ_c3065 1.1e-93 349.7 Caulobacterales Bacteria 1MU3W@1224,2KGMQ@204458,2TT5X@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_01122 366602.Caul_3532 1.7e-63 249.6 Alphaproteobacteria Bacteria 1R41P@1224,2TRY2@28211,COG2267@1,COG2267@2 NA|NA|NA I Alpha beta hydrolase MAG.T12.39_01123 366602.Caul_3065 8.1e-134 483.4 Alphaproteobacteria 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MWRK@1224,2U14P@28211,COG0604@1,COG0604@2 NA|NA|NA C Alcohol dehydrogenase zinc-binding domain protein MAG.T12.39_01124 1429916.X566_07680 1.4e-79 302.8 Bradyrhizobiaceae 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1MXZY@1224,2U2AQ@28211,3JWWA@41294,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T12.39_01125 402881.Plav_2036 5.6e-69 268.9 Alphaproteobacteria Bacteria 1QV2F@1224,2U8KM@28211,COG2267@1,COG2267@2,COG2771@1,COG2771@2 NA|NA|NA IK Transcriptional regulator, LuxR family hydrolase, alpha beta fold family MAG.T12.39_01127 450851.PHZ_c2284 5.8e-170 603.6 Caulobacterales mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1MUMW@1224,2KFA1@204458,2TTQ2@28211,COG1077@1,COG1077@2 NA|NA|NA D TIGRFAM cell shape determining protein, MreB Mrl family MAG.T12.39_01128 1122604.JONR01000006_gene2731 1.5e-88 332.8 Xanthomonadales Bacteria 1QRDD@1224,1RQ6U@1236,1X93S@135614,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T12.39_01129 450851.PHZ_c2288 4.4e-86 324.7 Caulobacterales MA20_39710 Bacteria 1PHRI@1224,2KHJQ@204458,2TUAQ@28211,COG0697@1,COG0697@2 NA|NA|NA EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily MAG.T12.39_01130 450851.PHZ_c2289 2.9e-253 880.9 Caulobacterales leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS10690,iYO844.BSU28280 Bacteria 1MUNQ@1224,2KFXA@204458,2TSCJ@28211,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) MAG.T12.39_01131 1292034.OR37_03588 1.4e-79 302.8 Caulobacterales Bacteria 1QV55@1224,2KGS7@204458,2UAAB@28211,COG0398@1,COG0398@2 NA|NA|NA S PFAM SNARE associated Golgi protein MAG.T12.39_01132 257313.BP2072 2.7e-39 168.7 Alcaligenaceae Bacteria 1RH28@1224,2C852@1,2VSQ3@28216,32YB2@2,3T6ZC@506 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T12.39_01133 450851.PHZ_c2292 2.5e-188 664.8 Caulobacterales aatA 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1MW0Z@1224,2KFYV@204458,2TRPK@28211,COG0436@1,COG0436@2 NA|NA|NA E aminotransferase class I and II MAG.T12.39_01135 450851.PHZ_c1120 3e-128 464.9 Caulobacterales Bacteria 1N5ZI@1224,2KITC@204458,2TS7X@28211,COG0596@1,COG0596@2 NA|NA|NA S Serine aminopeptidase, S33 MAG.T12.39_01136 1292034.OR37_04022 2.4e-149 535.0 Caulobacterales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1MWW8@1224,2KFMS@204458,2TS53@28211,COG0596@1,COG0596@2 NA|NA|NA E Belongs to the peptidase S33 family MAG.T12.39_01137 1071679.BG57_21225 1.1e-25 122.9 Burkholderiaceae Bacteria 1KA9S@119060,1MZJ4@1224,2VWQY@28216,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) MAG.T12.39_01138 366602.Caul_1601 7.7e-127 460.3 Caulobacterales ephA GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575 2.7.10.2,3.3.2.9 ko:K01253,ko:K08253 ko00980,ko04976,ko05204,map00980,map04976,map05204 R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443 RC01447,RC01728,RC01764,RC02528 ko00000,ko00001,ko01000,ko01002 Bacteria 1QU7K@1224,2KHIG@204458,2TW27@28211,COG2267@1,COG2267@2 NA|NA|NA I PFAM alpha beta hydrolase MAG.T12.39_01139 450851.PHZ_c2276 6.6e-141 507.3 Caulobacterales ydhC ko:K07552,ko:K18552 br01600,ko00000,ko01504,ko02000 2.A.1.2,2.A.1.2.3 Bacteria 1QU36@1224,2KK93@204458,2TVXA@28211,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T12.39_01140 1415780.JPOG01000001_gene749 1.8e-73 283.1 Gammaproteobacteria lys1 Bacteria 1MXX6@1224,1S2W6@1236,COG1748@1,COG1748@2 NA|NA|NA E Saccharopine dehydrogenase MAG.T12.39_01141 1333998.M2A_2840 1.7e-25 122.9 Alphaproteobacteria Bacteria 1RG6C@1224,2U7MC@28211,COG1309@1,COG1309@2 NA|NA|NA K BetI-type transcriptional repressor, C-terminal MAG.T12.39_01142 509190.Cseg_1475 2.4e-28 131.7 Caulobacterales ygdD Bacteria 1MZX3@1224,2KHG6@204458,2UGS5@28211,COG2363@1,COG2363@2 NA|NA|NA S Protein of unknown function (DUF423) MAG.T12.39_01143 1333998.M2A_0478 6.5e-188 663.7 Alphaproteobacteria nylA 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1MWWQ@1224,2TSN9@28211,COG0154@1,COG0154@2 NA|NA|NA J Belongs to the amidase family MAG.T12.39_01144 450851.PHZ_c2273 2.8e-182 644.8 Caulobacterales GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016769,GO:0016999,GO:0017144,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046440,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 ko:K01845,ko:K21585 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272,R11607 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MUY5@1224,2KHSM@204458,2TT6G@28211,COG0001@1,COG0001@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T12.39_01145 666684.AfiDRAFT_1232 1.3e-42 179.5 Bradyrhizobiaceae Bacteria 1RIDY@1224,2U9GU@28211,3K4QG@41294,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) MAG.T12.39_01146 384765.SIAM614_25617 3.6e-42 178.7 Alphaproteobacteria ko:K07274 ko00000,ko02000 9.B.99.1 Bacteria 1REKJ@1224,2U37S@28211,COG3713@1,COG3713@2 NA|NA|NA M COG3713 Outer membrane protein V MAG.T12.39_01147 450851.PHZ_c2272 3.2e-100 372.1 Caulobacterales hcaT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.5.1.2 ko:K00286,ko:K05820 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.27 iECIAI39_1322.ECIAI39_2737,iEcSMS35_1347.EcSMS35_2688,iSFV_1184.SFV_2584,iSF_1195.SF2583,iS_1188.S2755 Bacteria 1MVZI@1224,2KFFC@204458,2U5H1@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_01148 450851.PHZ_c2270 3.6e-148 531.2 Caulobacterales adh4 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MXUX@1224,2KGCK@204458,2TTWF@28211,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T12.39_01149 1123240.ATVO01000005_gene1789 5.4e-47 194.1 Sphingomonadales ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 1N2YQ@1224,2KD23@204457,2TRRN@28211,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated MAG.T12.39_01150 450851.PHZ_c2254 5.6e-110 405.6 Caulobacterales 3.2.1.97 ko:K02004,ko:K17624 M00258 ko00000,ko00002,ko01000,ko02000 3.A.1 GH101 Bacteria 1PS7P@1224,2KFH5@204458,2V4ES@28211,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T12.39_01151 1088721.NSU_2209 2e-55 222.6 Sphingomonadales Bacteria 1MWJD@1224,2ANQE@1,2K5A1@204457,2U7P7@28211,31DQ0@2 NA|NA|NA S Domain of unknown function (DUF4163) MAG.T12.39_01152 450851.PHZ_c1095 0.0 1158.7 Caulobacterales mutB GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044464,GO:0046459,GO:0071704,GO:0071944 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUXX@1224,2KF12@204458,2TQYC@28211,COG1884@1,COG1884@2,COG2185@1,COG2185@2 NA|NA|NA I PFAM Methylmalonyl-CoA mutase MAG.T12.39_01153 450851.PHZ_c1096 4.4e-152 544.7 Caulobacterales mutA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 2.7.7.7,5.4.99.2,5.4.99.63 ko:K01847,ko:K03763,ko:K14447 ko00230,ko00240,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko03030,ko03430,ko03440,map00230,map00240,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map03030,map03430,map03440 M00260,M00373,M00376,M00741 R00375,R00376,R00377,R00378,R00833,R09292 RC00395,RC02795,RC02835 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1NR2K@1224,2KEYN@204458,2TSYT@28211,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase MAG.T12.39_01154 1207063.P24_08946 3.5e-31 140.6 Rhodospirillales stbC ko:K21495 ko00000,ko02048 Bacteria 1N8BI@1224,2JTXE@204441,2UBTT@28211,COG4691@1,COG4691@2 NA|NA|NA S Plasmid stability protein MAG.T12.39_01155 398525.KB900701_gene2974 4e-53 214.2 Bradyrhizobiaceae vapC ko:K07062 ko00000,ko01000,ko02048 Bacteria 1MZQC@1224,2U73E@28211,3JZ6X@41294,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T12.39_01156 1280954.HPO_03129 1.7e-146 525.8 Alphaproteobacteria estC Bacteria 1QD0J@1224,2U189@28211,COG1680@1,COG1680@2 NA|NA|NA V COG1680 Beta-lactamase class C and other penicillin binding proteins MAG.T12.39_01157 1280954.HPO_03129 5.6e-150 537.3 Alphaproteobacteria estC Bacteria 1QD0J@1224,2U189@28211,COG1680@1,COG1680@2 NA|NA|NA V COG1680 Beta-lactamase class C and other penicillin binding proteins MAG.T12.39_01158 190650.CC_2372 1.1e-154 552.7 Caulobacterales 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371,ko:K15329 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Bacteria 1MU0U@1224,2KFAG@204458,2TS5U@28211,COG2070@1,COG2070@2 NA|NA|NA S 2-nitropropane dioxygenase MAG.T12.39_01159 742159.HMPREF0004_1187 7.8e-125 454.1 Alcaligenaceae hsrA_2 Bacteria 1MUDA@1224,2VI2I@28216,3T23T@506,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_01161 450851.PHZ_c2222 6.8e-84 317.0 Caulobacterales Bacteria 1Q1EP@1224,2KIT4@204458,2V5ZB@28211,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair MAG.T12.39_01165 1500894.JQNN01000001_gene1559 3e-139 502.3 Betaproteobacteria ko:K03929 ko00000,ko01000 CE10 Bacteria 1MVQZ@1224,2VJ7U@28216,COG2272@1,COG2272@2 NA|NA|NA I Belongs to the type-B carboxylesterase lipase family MAG.T12.39_01166 1292034.OR37_02174 0.0 1181.4 Alphaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MUNK@1224,2TRCG@28211,COG1629@1,COG4771@2 NA|NA|NA P receptor MAG.T12.39_01167 366602.Caul_1381 2.1e-43 182.2 Caulobacterales tdcF Bacteria 1RD3E@1224,2KIW8@204458,2U888@28211,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP MAG.T12.39_01168 1292034.OR37_02169 6.6e-205 720.3 Alphaproteobacteria 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWPH@1224,2U05G@28211,COG1231@1,COG1231@2 NA|NA|NA E Monoamine oxidase MAG.T12.39_01169 1349767.GJA_3070 9e-23 113.2 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T12.39_01170 1278971.AOGF01000034_gene1751 1.3e-06 60.1 Gammaproteobacteria Bacteria 1MZRW@1224,1SF0N@1236,2D0K9@1,32T8S@2 NA|NA|NA MAG.T12.39_01171 450851.PHZ_c2212 2.5e-165 588.6 Alphaproteobacteria Bacteria 1R0EP@1224,2TYQ7@28211,COG5323@1,COG5323@2 NA|NA|NA S Terminase RNaseH-like domain MAG.T12.39_01172 1211777.BN77_4166 4.8e-166 591.3 Rhizobiaceae 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1QVEE@1224,2TWDG@28211,4BHSG@82115,COG3170@1,COG3170@2 NA|NA|NA NU Phage P22-like portal protein MAG.T12.39_01173 1331060.RLDS_06945 1.4e-28 132.1 Sphingomonadales ko:K07726 ko00000,ko03000 Bacteria 1MZGM@1224,2K7M5@204457,2UB31@28211,COG2944@1,COG2944@2 NA|NA|NA K transcriptional regulator MAG.T12.39_01174 1402135.SUH3_16450 2.6e-31 141.4 Alphaproteobacteria higB-2 Bacteria 1N7N5@1224,2UGH7@28211,COG4737@1,COG4737@2 NA|NA|NA S Cytotoxic translational repressor of toxin-antitoxin stability system MAG.T12.39_01175 1211777.BN77_4167 3.4e-16 92.4 Alphaproteobacteria Bacteria 1NNPU@1224,2ENQ2@1,2UN0X@28211,33GBD@2 NA|NA|NA MAG.T12.39_01176 1211777.BN77_4169 3.8e-108 398.3 Rhizobiaceae Bacteria 1R8XM@1224,2C5GI@1,2TUME@28211,2Z8C1@2,4BJKS@82115 NA|NA|NA S P22 coat protein - gene protein 5 MAG.T12.39_01177 1211777.BN77_4171 4.2e-13 81.6 Alphaproteobacteria Bacteria 1NYD8@1224,2DWRQ@1,2UTQ9@28211,341KN@2 NA|NA|NA MAG.T12.39_01179 1304877.KI519399_gene5001 7.1e-11 74.3 Bradyrhizobiaceae Bacteria 1MYXI@1224,2V8W8@28211,3JZFN@41294,COG4675@1,COG4675@2 NA|NA|NA S Phage Tail Collar Domain MAG.T12.39_01182 595537.Varpa_1356 1.4e-52 213.0 Betaproteobacteria Bacteria 1RJW2@1224,2VSJI@28216,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase MAG.T12.39_01183 1304275.C41B8_05368 4.2e-28 132.9 Proteobacteria Bacteria 1RCNN@1224,28S81@1,2ZEJD@2 NA|NA|NA MAG.T12.39_01189 438753.AZC_0517 1.2e-29 136.7 Xanthobacteraceae ko:K09965 ko00000 Bacteria 1RK12@1224,2U9IH@28211,3F1DT@335928,COG3644@1,COG3644@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2239) MAG.T12.39_01191 366602.Caul_3601 3.4e-39 167.9 Caulobacterales MA20_21100 Bacteria 1N1FB@1224,2CN5Z@1,2KH23@204458,2UBV1@28211,32SGB@2 NA|NA|NA S Protein of unknown function (DUF2948) MAG.T12.39_01192 450851.PHZ_c2199 4.2e-178 630.9 Caulobacterales hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iYO844.BSU34910 Bacteria 1MUUF@1224,2KEYD@204458,2TSBN@28211,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine MAG.T12.39_01193 450851.PHZ_c2197 1.6e-69 268.9 Caulobacterales MA20_21090 Bacteria 1RA93@1224,2KGJ7@204458,2U741@28211,COG5328@1,COG5328@2 NA|NA|NA S Belongs to the UPF0262 family MAG.T12.39_01194 450851.PHZ_c2195 1.1e-30 138.7 Caulobacterales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1MZFU@1224,2KH0X@204458,2UBRU@28211,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T12.39_01195 1292034.OR37_01507 7.7e-55 220.3 Caulobacterales maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 ko:K03215,ko:K06287 ko00000,ko01000,ko03009 Bacteria 1RH6H@1224,2KGHH@204458,2TSS5@28211,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T12.39_01196 450851.PHZ_c2193 1.3e-100 373.2 Caulobacterales rng 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 1RG55@1224,2KGH2@204458,2U8TG@28211,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E G MAG.T12.39_01198 1280949.HAD_10490 4.3e-150 538.1 Hyphomonadaceae 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX9R@1224,2TR4U@28211,43Z0J@69657,COG0654@1,COG0654@2 NA|NA|NA C FAD binding domain MAG.T12.39_01199 1280949.HAD_10485 1.7e-103 382.5 Hyphomonadaceae Bacteria 1MUPF@1224,2TQQG@28211,43Z7C@69657,COG0179@1,COG0179@2 NA|NA|NA G Fumarylacetoacetate (FAA) hydrolase family MAG.T12.39_01200 1280949.HAD_10480 3.3e-108 398.3 Hyphomonadaceae Bacteria 1MVIQ@1224,2U460@28211,43Z4I@69657,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase bleomycin resistance protein dioxygenase MAG.T12.39_01201 383381.EH30_04450 7.6e-35 154.1 Sphingomonadales Bacteria 1N6P0@1224,2K8DB@204457,2UHTJ@28211,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T12.39_01203 450851.PHZ_c2192 8.5e-101 373.6 Caulobacterales exbB ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1MXHR@1224,2KFAK@204458,2TQNN@28211,COG0811@1,COG0811@2 NA|NA|NA U MotA TolQ ExbB proton channel MAG.T12.39_01204 450851.PHZ_c2191 6.6e-51 206.8 Caulobacterales exbD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0023052,GO:0031224,GO:0031226,GO:0031647,GO:0031992,GO:0032991,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0065008,GO:0071944,GO:0098796,GO:0098797 ko:K03559,ko:K03560 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 iPC815.YPO0683 Bacteria 1RDJZ@1224,2KGFK@204458,2U77T@28211,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR MAG.T12.39_01205 450851.PHZ_c2190 7.5e-65 253.8 Caulobacterales ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1RI3K@1224,2KGR4@204458,2UA6S@28211,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T12.39_01207 1449049.JONW01000008_gene352 4.5e-216 757.3 Caulobacterales ko:K11159 ko00000 Bacteria 1MY1X@1224,2KI00@204458,2TS7A@28211,COG3670@1,COG3670@2 NA|NA|NA Q dioxygenase MAG.T12.39_01208 1449049.JONW01000008_gene354 4.1e-91 341.3 Alphaproteobacteria yfhH 1.3.1.22 ko:K12343 ko00140,map00140 R02208,R02497,R08954,R10242 RC00145 ko00000,ko00001,ko01000 Bacteria 1MXCP@1224,2VG88@28211,COG3752@1,COG3752@2 NA|NA|NA S Protein of unknown function (DUF1295) MAG.T12.39_01209 450851.PHZ_c1155 1.7e-201 708.8 Caulobacterales matB ko:K18661 ko00280,map00280 R03383 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MU6G@1224,2KIKM@204458,2TR2W@28211,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_01211 709797.CSIRO_4121 2.4e-118 431.8 Bradyrhizobiaceae MA20_36865 Bacteria 1NR18@1224,2TVGP@28211,3JU0D@41294,COG2043@1,COG2043@2 NA|NA|NA S Uncharacterised ArCR, COG2043 MAG.T12.39_01212 450851.PHZ_c2668 2.3e-86 326.2 Caulobacterales ko:K21470,ko:K21572 ko00000,ko01002,ko01011,ko02000 8.A.46.1,8.A.46.3 Bacteria 1MV14@1224,2KF4H@204458,2TRJ9@28211,COG2989@1,COG2989@2 NA|NA|NA S L,D-transpeptidase catalytic domain MAG.T12.39_01213 335283.Neut_2531 1.7e-45 189.1 Nitrosomonadales ycbK ko:K02395 ko00000,ko02035 Bacteria 1MWW2@1224,2VRCS@28216,3737H@32003,COG3108@1,COG3108@2 NA|NA|NA S Bacterial protein of unknown function (DUF882) MAG.T12.39_01215 450851.PHZ_c0985 2.2e-172 611.7 Caulobacterales recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1MU3C@1224,2KF1D@204458,2TRPR@28211,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage MAG.T12.39_01216 450851.PHZ_c0987 0.0 1340.5 Caulobacterales alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 Bacteria 1MU9A@1224,2KFSE@204458,2TQV4@28211,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain MAG.T12.39_01217 1429916.X566_19625 1.8e-94 352.4 Alphaproteobacteria Bacteria 1R25N@1224,2TZB2@28211,COG0300@1,COG0300@2 NA|NA|NA S NAD dependent epimerase/dehydratase family MAG.T12.39_01218 450851.PHZ_c2627 3.3e-308 1063.9 Caulobacterales dpp4 3.4.14.5 ko:K01278,ko:K01990 ko04974,map04974 M00254 ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko04090,ko04147 3.A.1 Bacteria 1P6E1@1224,2KFW9@204458,2TRVE@28211,COG1506@1,COG1506@2 NA|NA|NA E peptidase S9B dipeptidylpeptidase IV domain protein MAG.T12.39_01219 450851.PHZ_c0989 1.6e-211 741.9 Caulobacterales icd 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MUIB@1224,2KFF1@204458,2TQWD@28211,COG0538@1,COG0538@2 NA|NA|NA C Belongs to the isocitrate and isopropylmalate dehydrogenases family MAG.T12.39_01220 450851.PHZ_c0991 2.4e-99 368.6 Caulobacterales trmJ GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.200,3.5.1.19,6.1.1.16 ko:K01883,ko:K02533,ko:K08281,ko:K15396 ko00760,ko00970,ko01100,map00760,map00970,map01100 M00359,M00360 R01268,R03650 RC00055,RC00100,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1N47Y@1224,2KFX7@204458,2TS8J@28211,COG0565@1,COG0565@2 NA|NA|NA J tRNA rRNA methyltransferase MAG.T12.39_01221 1449049.JONW01000006_gene3180 5.8e-148 530.8 Caulobacterales Bacteria 1MWTW@1224,2KG91@204458,2TUR1@28211,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T12.39_01222 59538.XP_005971548.1 1e-97 362.8 Eukaryota ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Eukaryota COG0522@1,KOG3301@2759 NA|NA|NA J positive regulation of translational fidelity MAG.T12.39_01223 1122603.ATVI01000006_gene117 4e-66 258.5 Xanthomonadales Bacteria 1RF0S@1224,1S53W@1236,1XBZ3@135614,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_01224 285514.JNWO01000045_gene4027 3e-21 108.2 Actinobacteria Bacteria 2INKP@201174,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_01225 450851.PHZ_c0995 1.1e-14 86.3 Caulobacterales Bacteria 1Q719@1224,2A1RM@1,2KJJX@204458,2V6Z4@28211,30Q06@2 NA|NA|NA MAG.T12.39_01226 450851.PHZ_c0998 6.1e-52 210.3 Caulobacterales ko:K07107 ko00000,ko01000 Bacteria 1N06V@1224,2KGXE@204458,2UCAQ@28211,COG0824@1,COG0824@2 NA|NA|NA S Acyl-ACP thioesterase MAG.T12.39_01227 509190.Cseg_1200 4.1e-45 187.2 Caulobacterales grlA ko:K07390 ko00000,ko03029,ko03110 Bacteria 1MZ4V@1224,2KGT5@204458,2U9QB@28211,COG0278@1,COG0278@2 NA|NA|NA C Belongs to the glutaredoxin family. Monothiol subfamily MAG.T12.39_01228 450851.PHZ_c1000 2.4e-26 124.4 Caulobacterales colA 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1R3MM@1224,2KHBP@204458,2UBUW@28211,COG0271@1,COG0271@2 NA|NA|NA T Belongs to the BolA IbaG family MAG.T12.39_01230 450851.PHZ_c1001 4.9e-184 650.6 Caulobacterales Bacteria 1MVPR@1224,2KFVB@204458,2TRWZ@28211,COG1680@1,COG1680@2 NA|NA|NA V beta-lactamase MAG.T12.39_01231 450851.PHZ_c1002 1.5e-54 219.2 Caulobacterales cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1RHXH@1224,2KISA@204458,2UACN@28211,COG1546@1,COG1546@2 NA|NA|NA S Competence-damaged protein MAG.T12.39_01232 450851.PHZ_c1010 0.0 1238.0 Caulobacterales purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1MYN4@1224,2KFW0@204458,2TRGM@28211,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T12.39_01233 1248916.ANFY01000005_gene2854 1.4e-57 229.2 Sphingomonadales Bacteria 1RG54@1224,2DKWS@1,2K5RV@204457,2UDCY@28211,30N64@2 NA|NA|NA S Domain of unknown function (DUF4188) MAG.T12.39_01234 1123267.JONN01000001_gene2307 9.8e-145 520.4 Sphingomonadales ko:K03294 ko00000 2.A.3.2 Bacteria 1MXNJ@1224,2K2U3@204457,2TRNX@28211,COG0531@1,COG0531@2 NA|NA|NA E C-terminus of AA_permease MAG.T12.39_01235 450851.PHZ_c1013 4.9e-98 364.0 Caulobacterales purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4Y@1224,2KF3E@204458,2TS67@28211,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T12.39_01236 450851.PHZ_c1015 5.4e-25 119.8 Caulobacterales purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1N83G@1224,2KHAS@204458,2UF7S@28211,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T12.39_01238 450851.PHZ_c1920 3.4e-119 434.9 Caulobacterales MA20_16375 Bacteria 1MY0Y@1224,2KFT2@204458,2TRMW@28211,COG3173@1,COG3173@2 NA|NA|NA S Phosphotransferase enzyme family MAG.T12.39_01239 450851.PHZ_c1919 1.5e-29 135.6 Caulobacterales Bacteria 1NAVB@1224,2DRHM@1,2KHB0@204458,2UFZ1@28211,33799@2 NA|NA|NA MAG.T12.39_01240 1122614.JHZF01000014_gene2717 3.4e-109 401.4 Oceanicola MA20_16335 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 iAF987.Gmet_2224 Bacteria 1PESW@1224,2PEMS@252301,2V7VH@28211,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_01241 1122929.KB908215_gene1110 2e-78 300.1 Alphaproteobacteria MA20_09520 Bacteria 1P6JE@1224,2TV39@28211,COG1807@1,COG1807@2 NA|NA|NA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family MAG.T12.39_01242 1122929.KB908215_gene1111 3.5e-104 385.2 Alphaproteobacteria MA20_09515 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 1MV8J@1224,2TTYF@28211,COG0463@1,COG0463@2,COG2246@1,COG2246@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T12.39_01243 1121123.AUAO01000001_gene957 1.8e-23 115.9 Caulobacterales Bacteria 1N7K4@1224,2EF4R@1,2KH9G@204458,2UIQW@28211,338XX@2 NA|NA|NA MAG.T12.39_01244 509190.Cseg_2808 6.8e-62 243.4 Caulobacterales Bacteria 1RHMZ@1224,2KG98@204458,2U9H4@28211,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease MAG.T12.39_01245 450851.PHZ_c1299 8.9e-104 383.3 Caulobacterales ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1MU8H@1224,2KF26@204458,2TV1D@28211,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family MAG.T12.39_01246 450851.PHZ_c1300 1.3e-181 642.5 Caulobacterales MA20_36195 ko:K09919 ko00000 Bacteria 1MU35@1224,2KFX4@204458,2TS5I@28211,COG3146@1,COG3146@2 NA|NA|NA S Peptidogalycan biosysnthesis/recognition MAG.T12.39_01247 450851.PHZ_c1301 1.2e-60 239.2 Caulobacterales hit ko:K02503 ko00000,ko04147 Bacteria 1RDCJ@1224,2KGS5@204458,2U956@28211,COG0537@1,COG0537@2 NA|NA|NA FG PFAM histidine triad (HIT) protein MAG.T12.39_01248 450851.PHZ_c1984 4e-143 514.2 Caulobacterales cbiC 5.4.99.60,5.4.99.61 ko:K06042 ko00860,ko01100,map00860,map01100 R05177,R05814 RC01292,RC01980 ko00000,ko00001,ko01000 Bacteria 1P7TI@1224,2KEZG@204458,2U1XP@28211,COG2082@1,COG2082@2 NA|NA|NA H Precorrin-8x methylmutase MAG.T12.39_01249 1280944.HY17_15135 2.8e-112 411.8 Alphaproteobacteria tadA 3.5.4.33,3.8.1.5 ko:K01563,ko:K11991 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223 RC00477,RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000,ko03016 Bacteria 1MUSF@1224,2TSK5@28211,COG0596@1,COG0596@2 NA|NA|NA S Alpha beta hydrolase MAG.T12.39_01250 450851.PHZ_c1983 4.7e-140 504.2 Caulobacterales ko:K07119 ko00000 Bacteria 1MUC2@1224,2KFCR@204458,2TQYM@28211,COG2130@1,COG2130@2 NA|NA|NA S N-terminal domain of oxidoreductase MAG.T12.39_01251 450851.PHZ_c1982 9.2e-106 390.2 Caulobacterales gnnA ko:K09949 ko00000 iAF987.Gmet_2352 Bacteria 1MV7C@1224,2KF2J@204458,2U17I@28211,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase MAG.T12.39_01252 450851.PHZ_c1981 7.2e-62 243.4 Caulobacterales btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 1RD1R@1224,2KK2X@204458,2TU17@28211,COG0386@1,COG0386@2 NA|NA|NA O Glutathione peroxidase MAG.T12.39_01253 1230476.C207_03286 9.7e-123 447.6 Bradyrhizobiaceae Bacteria 1MVMG@1224,2TRVB@28211,3JR8N@41294,COG0457@1,COG0457@2,COG3914@1,COG3914@2 NA|NA|NA O Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MAG.T12.39_01254 1090319.KE386571_gene3067 4.8e-142 511.1 Sphingomonadales kgtP ko:K03761 ko00000,ko02000 2.A.1.6.2 Bacteria 1MVZG@1224,2K1Z1@204457,2TRS1@28211,COG0477@1,COG0477@2 NA|NA|NA EGP Transporter MAG.T12.39_01255 1449049.JONW01000012_gene75 6.5e-283 979.5 Caulobacterales ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUTQ@1224,2KFUQ@204458,2TRTQ@28211,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family MAG.T12.39_01256 450851.PHZ_c1975 7.3e-52 210.7 Caulobacterales nnrU Bacteria 1RDV6@1224,2KK6X@204458,2TVWM@28211,COG4094@1,COG4094@2 NA|NA|NA S NnrU protein MAG.T12.39_01257 69395.JQLZ01000010_gene4127 2e-41 175.3 Alphaproteobacteria Bacteria 1QVGU@1224,2UTNY@28211,COG0784@1,COG0784@2 NA|NA|NA T cheY-homologous receiver domain MAG.T12.39_01258 1449076.JOOE01000002_gene1207 1.1e-102 380.6 Sphingomonadales Bacteria 1NRP8@1224,2K2UP@204457,2TRHH@28211,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T12.39_01259 1161401.ASJA01000003_gene2866 1.1e-165 590.9 Hyphomonadaceae Bacteria 1R9IJ@1224,2TQZ5@28211,43Z0I@69657,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T12.39_01260 450851.PHZ_c1973 1.7e-113 415.6 Caulobacterales xthA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVII@1224,2KG3J@204458,2TR5J@28211,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III MAG.T12.39_01261 1449049.JONW01000012_gene69 2.5e-40 171.4 Caulobacterales erpA ko:K07400,ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 1RHCW@1224,2KGPP@204458,2UBR8@28211,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T12.39_01262 450851.PHZ_c1968 4.1e-172 610.9 Caulobacterales dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 1MVQ2@1224,2KG4A@204458,2TRCD@28211,COG0232@1,COG0232@2 NA|NA|NA F dGTPase family. Type 2 subfamily MAG.T12.39_01263 450851.PHZ_c1967 1e-39 170.6 Caulobacterales Bacteria 1QVFI@1224,2KGTA@204458,2TWDN@28211,COG3087@1,COG3087@2 NA|NA|NA D PFAM Sporulation MAG.T12.39_01264 450851.PHZ_c1966 9.7e-122 443.4 Caulobacterales nagZ 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 GH3 Bacteria 1MVAJ@1224,2KF4G@204458,2TRJK@28211,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 MAG.T12.39_01265 450851.PHZ_c1965 8.8e-105 386.7 Caulobacterales scpA ko:K05896 ko00000,ko03036 Bacteria 1MVCN@1224,2KEZR@204458,2TS1V@28211,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves MAG.T12.39_01266 450851.PHZ_c1964 3.3e-84 318.2 Caulobacterales scpB ko:K06024 ko00000,ko03036 Bacteria 1PUA6@1224,2KF90@204458,2TU64@28211,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves MAG.T12.39_01267 1292034.OR37_03551 8.1e-15 85.9 Caulobacterales tatA GO:0003674,GO:0005215 ko:K03116,ko:K03425 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1PJF0@1224,2KH5H@204458,2VCG6@28211,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system MAG.T12.39_01268 69395.JQLZ01000001_gene2656 3.8e-27 127.9 Caulobacterales tatB GO:0003674,GO:0005215 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1N73F@1224,2KH39@204458,2UF4Z@28211,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation MAG.T12.39_01269 450851.PHZ_c1961 1.1e-103 383.3 Caulobacterales tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1MVAY@1224,2KFZ7@204458,2TTIX@28211,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides MAG.T12.39_01270 450851.PHZ_c1960 2.2e-179 635.2 Caulobacterales serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1MUJF@1224,2KFZC@204458,2TR4T@28211,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) MAG.T12.39_01271 450851.PHZ_c1959 7.9e-106 390.2 Caulobacterales surE 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1MVHE@1224,2KFJK@204458,2TQXZ@28211,COG0496@1,COG0496@2 NA|NA|NA S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates MAG.T12.39_01272 190650.CC_1997 7.8e-88 330.1 Caulobacterales pcm 2.1.1.77 ko:K00573,ko:K02652 ko00000,ko01000,ko02035,ko02044 3.A.15.2 Bacteria 1MXQC@1224,2KFWY@204458,2TVCY@28211,COG2518@1,COG2518@2 NA|NA|NA J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins MAG.T12.39_01273 1449049.JONW01000012_gene56 3.3e-76 293.1 Caulobacterales nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 3.4.24.75 ko:K06194,ko:K08259,ko:K12943,ko:K21471 ko00000,ko01000,ko01002,ko01011 1.A.34.1.2 Bacteria 1QV29@1224,2KK6Y@204458,2TW8Q@28211,COG0739@1,COG0739@2,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif MAG.T12.39_01274 450851.PHZ_c1956 4.5e-112 411.0 Caulobacterales MA20_41470 ko:K06923 ko00000 Bacteria 1MVMX@1224,2KFWE@204458,2TTFE@28211,COG2607@1,COG2607@2 NA|NA|NA S Protein of unknown function (DUF815) MAG.T12.39_01275 450851.PHZ_c1955 1.4e-35 155.6 Caulobacterales yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1MZT2@1224,2KGZI@204458,2UBZ6@28211,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit YajC MAG.T12.39_01276 509190.Cseg_1436 1.8e-183 649.0 Caulobacterales secD ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1MV5U@1224,2KF0Q@204458,2TQYG@28211,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T12.39_01277 1382303.JPOM01000001_gene1530 2.1e-97 362.5 Caulobacterales secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1MU74@1224,2KG2T@204458,2TSFW@28211,COG0341@1,COG0341@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T12.39_01278 450851.PHZ_c1952 1.1e-30 139.4 Caulobacterales MA20_41450 Bacteria 1N083@1224,2KH9U@204458,2U95K@28211,COG3737@1,COG3737@2 NA|NA|NA S Protein of unknown function (DUF498/DUF598) MAG.T12.39_01279 190650.CC_1988 1.8e-78 298.9 Caulobacterales Bacteria 1RFIZ@1224,2KGBT@204458,2U7B1@28211,COG3748@1,COG3748@2 NA|NA|NA S Urate oxidase N-terminal MAG.T12.39_01280 450851.PHZ_c1950 9e-50 203.8 Caulobacterales crtB 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1MX4W@1224,2KH6E@204458,2U08T@28211,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase MAG.T12.39_01281 450851.PHZ_c1949 1.6e-223 781.9 Caulobacterales trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 ko00000,ko01000,ko03016,ko03036 Bacteria 1MWNQ@1224,2KF1A@204458,2TR6M@28211,COG1206@1,COG1206@2 NA|NA|NA J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs MAG.T12.39_01282 450851.PHZ_c1948 9.9e-33 147.5 Caulobacterales Bacteria 1NA96@1224,2DNE7@1,2KH4X@204458,2UFJ0@28211,32X2M@2 NA|NA|NA MAG.T12.39_01283 450851.PHZ_c1947 1.2e-82 312.8 Caulobacterales 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1Q05U@1224,2KI2X@204458,2U5IH@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain MAG.T12.39_01284 450851.PHZ_c1946 0.0 1706.8 Caulobacterales uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1MW0W@1224,2KFTI@204458,2TQK9@28211,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T12.39_01285 1280952.HJA_06452 2.7e-90 338.6 Hyphomonadaceae MA20_06735 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXHV@1224,2TTEG@28211,43ZXQ@69657,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T12.39_01286 1549858.MC45_04540 9.8e-140 503.4 Sphingomonadales 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 1MWEW@1224,2K0GT@204457,2TR5C@28211,COG2355@1,COG2355@2 NA|NA|NA E Zn-dependent dipeptidase, microsomal dipeptidase MAG.T12.39_01287 450851.PHZ_c1937 5.2e-43 180.6 Caulobacterales flbY Bacteria 1N197@1224,2E0PV@1,2KH4C@204458,2UCAE@28211,32W8K@2 NA|NA|NA MAG.T12.39_01288 1292034.OR37_03673 3.6e-16 90.9 Caulobacterales flgJ ko:K02395,ko:K08309 ko00000,ko01000,ko01011,ko02035 GH23 Bacteria 1N7K5@1224,2KH5E@204458,2UFY2@28211,COG3951@1,COG3951@2 NA|NA|NA MNO Rod binding protein MAG.T12.39_01289 1292034.OR37_03674 7.2e-138 497.3 Caulobacterales flgI GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 ko:K02394 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MVKW@1224,2KFHS@204458,2TQNX@28211,COG1706@1,COG1706@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation MAG.T12.39_01290 450851.PHZ_c1934 2.9e-23 114.4 Caulobacterales fliX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1N7R1@1224,2E5SK@1,2KHAD@204458,2UFAX@28211,330GZ@2 NA|NA|NA N flagellar assembly MAG.T12.39_01291 450851.PHZ_c1933 1.2e-60 239.2 Caulobacterales dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 1RD08@1224,2KGGH@204458,2U74V@28211,COG1734@1,COG1734@2 NA|NA|NA T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters MAG.T12.39_01292 1120919.AUBI01000004_gene2000 1.3e-144 519.6 Rhodospirillales aspB Bacteria 1MW0Z@1224,2JPKG@204441,2TS06@28211,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase MAG.T12.39_01293 13690.CP98_01110 3.5e-29 135.6 Alphaproteobacteria Bacteria 1R8VC@1224,2C3WA@1,2U8X3@28211,2Z8P1@2 NA|NA|NA MAG.T12.39_01294 1123072.AUDH01000011_gene3638 1.8e-173 615.9 Rhodospirillales nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9U@1224,2JPMK@204441,2TRAU@28211,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source MAG.T12.39_01295 1449049.JONW01000009_gene4573 7.8e-39 167.5 Caulobacterales Bacteria 1NM0Y@1224,2ERSN@1,2KHIF@204458,2UN3K@28211,33JBV@2 NA|NA|NA MAG.T12.39_01296 450851.PHZ_c1928 3.5e-218 764.6 Caulobacterales atm1 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 ko:K06147,ko:K12531 ko02020,map02020 M00326 ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1NSKS@1224,2KF6P@204458,2UQAG@28211,COG5265@1,COG5265@2 NA|NA|NA V ABC transporter MAG.T12.39_01297 450851.PHZ_c1927 0.0 1433.7 Caulobacterales ttgE ko:K18989 M00720 ko00000,ko00002,ko02000 2.A.6.2.30 Bacteria 1MU48@1224,2KFKZ@204458,2TQT0@28211,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T12.39_01298 450851.PHZ_c1926 3.7e-103 381.7 Alphaproteobacteria ko:K18990 M00720 ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 Bacteria 1MVFN@1224,2TRSC@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T12.39_01299 626887.J057_06621 6.4e-62 243.4 Alteromonadaceae gloA GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1RCYX@1224,1S1Z9@1236,466XN@72275,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T12.39_01300 1090318.ATTI01000001_gene1619 6.2e-52 212.2 Sphingomonadales Bacteria 1MVMG@1224,2K26Q@204457,2TSGE@28211,COG0457@1,COG0457@2 NA|NA|NA S Sulfotransferase family MAG.T12.39_01301 1382303.JPOM01000001_gene1184 4.6e-122 444.5 Caulobacterales kamA GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 R00461 RC00303 ko00000,ko00001,ko01000,ko03012 iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Bacteria 1MUPJ@1224,2KHHW@204458,2TT31@28211,COG1509@1,COG1509@2 NA|NA|NA C Lysine-2,3-aminomutase MAG.T12.39_01302 509190.Cseg_3971 9.2e-139 500.0 Caulobacterales epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 ko:K04568 ko00000,ko01000,ko03012 Bacteria 1MU97@1224,2KG86@204458,2TRD4@28211,COG2269@1,COG2269@2 NA|NA|NA J class II (D K and N) MAG.T12.39_01303 1292034.OR37_00849 1.7e-83 315.5 Caulobacterales efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1MW2J@1224,2KG0A@204458,2TUWE@28211,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase MAG.T12.39_01304 509190.Cseg_1956 8.1e-136 490.3 Caulobacterales yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07007 ko00000 Bacteria 1MUGC@1224,2KF6G@204458,2TTXA@28211,COG2081@1,COG2081@2 NA|NA|NA S HI0933 family MAG.T12.39_01305 13689.BV96_03336 1.6e-23 116.3 Sphingomonadales Bacteria 1NJWW@1224,2K5ZH@204457,2UD8G@28211,COG3637@1,COG3637@2 NA|NA|NA M OmpA-like transmembrane domain MAG.T12.39_01307 450851.PHZ_c1902 1.1e-97 362.8 Caulobacterales ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MUDN@1224,2KG0M@204458,2TQJ9@28211,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_01308 450851.PHZ_c1900 9.2e-291 1006.1 Caulobacterales hrpB 3.6.4.13 ko:K03579 ko00000,ko01000 Bacteria 1MUEQ@1224,2KF9E@204458,2TRMJ@28211,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase MAG.T12.39_01309 450851.PHZ_c1898 2.7e-106 391.7 Caulobacterales spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1MWBE@1224,2KFUX@204458,2TT4Y@28211,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T12.39_01310 450851.PHZ_c1897 3.1e-119 434.9 Caulobacterales rlmI 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 1QSD4@1224,2KF6Q@204458,2TUFT@28211,COG1092@1,COG1092@2 NA|NA|NA J Belongs to the methyltransferase superfamily MAG.T12.39_01311 450851.PHZ_c1891 7.5e-196 690.6 Caulobacterales slt ko:K08309 ko00000,ko01000,ko01011 GH23 Bacteria 1MV3F@1224,2KF52@204458,2TRDB@28211,COG0741@1,COG0741@2 NA|NA|NA M Transglycosylase MAG.T12.39_01312 450851.PHZ_c1890 2.9e-130 471.5 Caulobacterales dapA GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUCM@1224,2KF17@204458,2TR5W@28211,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) MAG.T12.39_01313 190650.CC_1196 9.9e-66 256.1 Caulobacterales smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1RDFP@1224,2KGBK@204458,2U71I@28211,COG0691@1,COG0691@2 NA|NA|NA J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene MAG.T12.39_01314 450851.PHZ_c1888 1.9e-53 216.1 Alphaproteobacteria yobR GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 Bacteria 1RGJ0@1224,2U7Z3@28211,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family MAG.T12.39_01315 247633.GP2143_17716 2.9e-214 751.5 Gammaproteobacteria Bacteria 1MWWY@1224,1S1C2@1236,COG3653@1,COG3653@2 NA|NA|NA Q Amidohydrolase family MAG.T12.39_01316 450851.PHZ_c1886 8.6e-161 573.5 Caulobacterales dapE Bacteria 1MWJS@1224,2KFBQ@204458,2TUHT@28211,COG0624@1,COG0624@2 NA|NA|NA E Peptidase, M20 MAG.T12.39_01317 450851.PHZ_c1885 2.1e-96 358.6 Caulobacterales udgB GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MW91@1224,2KG7E@204458,2TSUP@28211,COG1573@1,COG1573@2 NA|NA|NA L uracil-DNA glycosylase MAG.T12.39_01318 450851.PHZ_c1884 1.6e-92 345.5 Caulobacterales Bacteria 1MUAE@1224,2KG33@204458,2TU5M@28211,COG1432@1,COG1432@2 NA|NA|NA S NYN domain MAG.T12.39_01319 194867.ALBQ01000044_gene1538 3.2e-61 241.9 Sphingomonadales gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1R6SG@1224,2K3UT@204457,2TUUY@28211,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase MAG.T12.39_01320 1216007.AOPM01000052_gene2247 2.3e-37 161.4 Pseudoalteromonadaceae sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 1MZ6P@1224,1S8TD@1236,2Q2TA@267888,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein MAG.T12.39_01321 1121948.AUAC01000003_gene2282 4.2e-74 285.0 Alphaproteobacteria Bacteria 1PQZA@1224,2UXJA@28211,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T12.39_01322 1123255.JHYS01000017_gene1411 1.6e-20 106.3 Comamonadaceae Bacteria 1RJVY@1224,29DIQ@1,2VTHH@28216,300GG@2,4AEF9@80864 NA|NA|NA S Protein of unknown function (DUF3617) MAG.T12.39_01324 13690.CP98_01302 8e-39 166.4 Sphingomonadales Bacteria 1RCZT@1224,2K4WC@204457,2U735@28211,COG3795@1,COG3795@2 NA|NA|NA S YCII-related domain MAG.T12.39_01325 506534.Rhein_1745 1.7e-177 629.0 Gammaproteobacteria map 1.17.1.1,3.4.11.18 ko:K00523,ko:K01265 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000,ko01002 Bacteria 1QXY6@1224,1T3K3@1236,COG0024@1,COG0024@2 NA|NA|NA J xaa-pro aminopeptidase MAG.T12.39_01327 1449049.JONW01000005_gene1383 1.2e-44 186.0 Caulobacterales Bacteria 1RH53@1224,2KIYZ@204458,2U9NS@28211,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T12.39_01328 1192868.CAIU01000019_gene2605 9e-137 493.4 Phyllobacteriaceae lysDH 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY1G@1224,2TU0J@28211,43JCZ@69277,COG1748@1,COG1748@2 NA|NA|NA E Saccharopine dehydrogenase MAG.T12.39_01329 1292034.OR37_02351 1.2e-203 716.1 Caulobacterales pcd GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW72@1224,2KF0T@204458,2TUN4@28211,COG1012@1,COG1012@2 NA|NA|NA C belongs to the aldehyde dehydrogenase family MAG.T12.39_01330 1208323.B30_05352 8e-69 267.7 Proteobacteria 3.4.16.4 ko:K01286 ko00000,ko01000 Bacteria 1R653@1224,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase class C and other penicillin binding proteins MAG.T12.39_01331 1240350.AMZE01000001_gene2847 3.5e-34 152.5 Gammaproteobacteria sdsB1 ko:K14057 ko00000,ko03000 Bacteria 1RI7F@1224,1S8C2@1236,COG0583@1,COG0583@2 NA|NA|NA K transcriptional regulator MAG.T12.39_01332 395963.Bind_1631 1.9e-216 759.2 Beijerinckiaceae Bacteria 1MWTW@1224,2TUR1@28211,3NBYV@45404,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) MAG.T12.39_01333 316057.RPD_2515 1.2e-20 107.1 Bradyrhizobiaceae ko:K01420,ko:K10914,ko:K21561 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1Q70G@1224,2UC77@28211,3K4MK@41294,COG0664@1,COG0664@2 NA|NA|NA K Cyclic nucleotide-monophosphate binding domain MAG.T12.39_01334 1282876.BAOK01000002_gene490 1e-11 76.6 Alphaproteobacteria Bacteria 1N7G0@1224,2UA2S@28211,COG1846@1,COG1846@2 NA|NA|NA K MarR family MAG.T12.39_01335 1282876.BAOK01000001_gene3065 3e-94 352.4 Alphaproteobacteria MA20_06615 Bacteria 1MVRV@1224,2TSMQ@28211,COG0534@1,COG0534@2 NA|NA|NA V Mate efflux family protein MAG.T12.39_01336 509190.Cseg_3938 8.9e-205 720.3 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QUVF@1224,2KJW7@204458,2TYQ1@28211,COG1629@1,COG1629@2 NA|NA|NA M TonB dependent receptor MAG.T12.39_01337 366602.Caul_2493 4.4e-11 74.3 Caulobacterales Bacteria 1NH29@1224,2EIJE@1,2KHEU@204458,2UJZ4@28211,33CAQ@2 NA|NA|NA S Psort location CytoplasmicMembrane, score MAG.T12.39_01338 1121123.AUAO01000003_gene2038 1.2e-35 156.4 Caulobacterales algT ko:K03088 ko00000,ko03021 Bacteria 1RD9G@1224,2KGJR@204458,2U92K@28211,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T12.39_01340 450851.PHZ_c1533 2.8e-101 375.2 Caulobacterales panB 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU3B@1224,2KFV2@204458,2TQT1@28211,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate MAG.T12.39_01341 450851.PHZ_c1534 4.1e-64 251.5 Caulobacterales Bacteria 1PSR3@1224,2KGIW@204458,2V4U9@28211,COG4649@1,COG4649@2 NA|NA|NA S Tetratricopeptide repeat-like domain MAG.T12.39_01342 509190.Cseg_2323 1e-137 496.9 Caulobacterales bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K17713 ko00000,ko02000 1.B.33.1 Bacteria 1MXIJ@1224,2KF7P@204458,2TUAD@28211,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain MAG.T12.39_01343 450851.PHZ_c1536 2.2e-203 715.3 Caulobacterales der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 ko:K03977 ko00000,ko03009 Bacteria 1MU9S@1224,2KF0V@204458,2TT38@28211,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis MAG.T12.39_01344 450851.PHZ_c1537 4e-88 331.3 Caulobacterales Bacteria 1MWBC@1224,2KF9W@204458,2TTQS@28211,COG1028@1,COG1028@2 NA|NA|NA IQ short-chain dehydrogenase MAG.T12.39_01345 69395.JQLZ01000008_gene2528 2e-95 355.9 Caulobacterales yfeH ko:K14347 ko00000,ko02000,ko04147 2.A.93.1 Bacteria 1MUMM@1224,2KFWM@204458,2TU7J@28211,COG0385@1,COG0385@2 NA|NA|NA S Bile acid sodium symporter MAG.T12.39_01346 450851.PHZ_c1539 2.8e-250 870.9 Caulobacterales purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1MU0V@1224,2KFPK@204458,2TR8V@28211,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine MAG.T12.39_01347 1292034.OR37_00054 9.2e-38 163.7 Caulobacterales cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1N80D@1224,2KH5A@204458,2VA4E@28211,COG1286@1,COG1286@2 NA|NA|NA S PFAM Colicin V production protein MAG.T12.39_01348 450851.PHZ_c1541 1.1e-197 696.0 Caulobacterales radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 1MUJQ@1224,2KFXB@204458,2TS6F@28211,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function MAG.T12.39_01349 366602.Caul_2506 1.1e-83 317.0 Caulobacterales alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008784,GO:0009058,GO:0009059,GO:0009078,GO:0009079,GO:0009252,GO:0009273,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0030170,GO:0030203,GO:0030632,GO:0034645,GO:0036094,GO:0036361,GO:0040007,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1MV0Q@1224,2KFTG@204458,2TQKD@28211,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids MAG.T12.39_01350 450851.PHZ_c1543 3.2e-222 777.7 Caulobacterales dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1MUG9@1224,2KFUP@204458,2TSF9@28211,COG0305@1,COG0305@2 NA|NA|NA L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins MAG.T12.39_01351 366602.Caul_2509 3e-270 937.9 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MUNK@1224,2KFMF@204458,2TRCG@28211,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T12.39_01352 1292034.OR37_00060 1.8e-75 288.9 Caulobacterales rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RD0R@1224,2KG9N@204458,2TSC9@28211,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA MAG.T12.39_01353 1292034.OR37_00061 4.1e-32 143.7 Caulobacterales rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ8U@1224,2KH2E@204458,2UC13@28211,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit MAG.T12.39_01354 450851.PHZ_c1546 6.1e-50 203.4 Caulobacterales rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 4.3.1.19 ko:K01754,ko:K02990 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,ko03010,map00260,map00290,map01100,map01110,map01130,map01200,map01230,map03010 M00178,M00570 R00220,R00996 RC00418,RC02600 br01610,ko00000,ko00001,ko00002,ko01000,ko03011,ko03029 Bacteria 1RH82@1224,2KGHW@204458,2U767@28211,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA MAG.T12.39_01355 1163409.UUA_16965 9.4e-50 203.4 Xanthomonadales bcp_2 1.11.1.15 ko:K03386,ko:K03564 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1RHSM@1224,1RQ8S@1236,1X6KF@135614,COG1225@1,COG1225@2 NA|NA|NA O Peroxiredoxin MAG.T12.39_01356 59538.XP_005977593.1 4.8e-134 484.2 Opisthokonta 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 Opisthokonta 38BXP@33154,COG0152@1,KOG2835@2759 NA|NA|NA F phosphoribosylaminoimidazolesuccinocarboxamide synthase activity MAG.T12.39_01357 1297865.APJD01000028_gene5203 1.8e-86 325.9 Bradyrhizobiaceae MA20_24410 Bacteria 1R5RX@1224,2U1DZ@28211,3JVKP@41294,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase-like superfamily MAG.T12.39_01358 1429916.X566_16385 7.5e-71 273.5 Bradyrhizobiaceae Bacteria 1MVWP@1224,2VGCN@28211,3K3SE@41294,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T12.39_01360 450851.PHZ_c1556 9.3e-163 579.7 Alphaproteobacteria MA20_17025 Bacteria 1MV9A@1224,2TTZZ@28211,COG1063@1,COG1063@2 NA|NA|NA E Zinc-binding dehydrogenase MAG.T12.39_01361 450851.PHZ_c1557 7.4e-140 503.4 Caulobacterales fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Bacteria 1MV6N@1224,2KF69@204458,2TRTT@28211,COG0331@1,COG0331@2 NA|NA|NA I malonyl CoA-acyl carrier protein transacylase MAG.T12.39_01362 450851.PHZ_c1558 1.2e-108 399.4 Caulobacterales Bacteria 1MU6X@1224,2KG6F@204458,2TQZG@28211,COG1028@1,COG1028@2 NA|NA|NA IQ 3-oxoacyl-(Acyl-carrier-protein) reductase MAG.T12.39_01363 450851.PHZ_c1559 2.6e-33 147.5 Caulobacterales acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1MZ4P@1224,2KGYW@204458,2UBWW@28211,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T12.39_01364 450851.PHZ_c1560 1.3e-200 705.7 Caulobacterales fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MU1X@1224,2KFB0@204458,2TR32@28211,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T12.39_01365 69395.JQLZ01000008_gene2549 6.5e-94 350.9 Caulobacterales mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 ko:K07082 ko00000 Bacteria 1MUQF@1224,2KFDJ@204458,2TR89@28211,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation MAG.T12.39_01366 450851.PHZ_c1562 6.9e-87 327.4 Caulobacterales yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 Bacteria 1MWRA@1224,2KF61@204458,2TS81@28211,COG1561@1,COG1561@2 NA|NA|NA S Domain of unknown function (DUF1732) MAG.T12.39_01367 450851.PHZ_c1563 1.5e-83 315.8 Caulobacterales gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 1MW92@1224,2KGBR@204458,2TSCQ@28211,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP MAG.T12.39_01368 935863.AWZR01000002_gene1099 3.9e-115 421.4 Xanthomonadales Bacteria 1MVEH@1224,1RPX5@1236,1X56H@135614,COG0667@1,COG0667@2 NA|NA|NA C oxidoreductases (related to aryl-alcohol dehydrogenases) MAG.T12.39_01370 59538.XP_005975965.1 2.2e-87 328.9 Mammalia Mammalia 38EES@33154,3BFPQ@33208,3CSHS@33213,3JCFY@40674,48A1F@7711,4940N@7742,COG0030@1,KOG0821@2759 NA|NA|NA A rRNA (adenine-N6,N6-)-dimethyltransferase activity MAG.T12.39_01371 450851.PHZ_c1709 7.1e-109 400.6 Caulobacterales pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_0056 Bacteria 1MX5W@1224,2KF73@204458,2TSKF@28211,COG1995@1,COG1995@2 NA|NA|NA H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) MAG.T12.39_01372 450851.PHZ_c1708 1e-150 540.0 Caulobacterales surA 5.2.1.8 ko:K02597,ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 1MVB3@1224,2KFBX@204458,2TSJ3@28211,COG0760@1,COG0760@2 NA|NA|NA M Chaperone SurA MAG.T12.39_01373 450851.PHZ_c1707 4.6e-223 781.2 Caulobacterales lptD ko:K04744 ko00000,ko02000 1.B.42.1 Bacteria 1MUJC@1224,2KF85@204458,2TR3B@28211,COG1452@1,COG1452@2 NA|NA|NA M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane MAG.T12.39_01374 450851.PHZ_c1706 6.7e-116 424.1 Caulobacterales lptG ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 1MVW3@1224,2KFP0@204458,2TR76@28211,COG0795@1,COG0795@2 NA|NA|NA S YjgP YjgQ family MAG.T12.39_01375 450851.PHZ_c1705 3.9e-127 461.5 Caulobacterales lptF ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 1MUF2@1224,2KF8P@204458,2TQUB@28211,COG0795@1,COG0795@2 NA|NA|NA S Permease, YjgP YjgQ family MAG.T12.39_01376 450851.PHZ_c1704 5.4e-198 697.2 Caulobacterales pepA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUF9@1224,2KFKG@204458,2TQU9@28211,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T12.39_01377 450851.PHZ_c1703 3.2e-48 198.0 Caulobacterales holC GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1RGVC@1224,2KGP1@204458,2U94V@28211,COG2927@1,COG2927@2 NA|NA|NA L DNA polymerase III MAG.T12.39_01378 509190.Cseg_2286 3.6e-14 84.3 Caulobacterales Bacteria 1NEW2@1224,2EDZQ@1,2KH82@204458,2UICH@28211,337UI@2 NA|NA|NA MAG.T12.39_01379 450851.PHZ_c1821 2.1e-242 845.1 Caulobacterales ko:K06158 ko00000,ko03012 Bacteria 1MU37@1224,2KFFN@204458,2TQRZ@28211,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T12.39_01380 3988.XP_002537979.1 2.2e-59 235.0 Eukaryota Eukaryota COG0105@1,KOG0888@2759 NA|NA|NA F Nucleoside diphosphate kinase MAG.T12.39_01381 59538.XP_005968334.1 6.2e-189 666.8 Cetartiodactyla Mammalia 38H6J@33154,3BC6X@33208,3CVK7@33213,3J1K7@40674,489NE@7711,48VKC@7742,4J3Z3@91561,COG1960@1,KOG0139@2759 NA|NA|NA I Short branched chain specific acyl-CoA dehydrogenase MAG.T12.39_01382 450851.PHZ_c3026 2.7e-166 591.7 Alphaproteobacteria mct GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016853,GO:0016866,GO:0016867,GO:0043427,GO:0071704 5.4.1.3 ko:K14470 ko00720,ko01120,ko01200,map00720,map01120,map01200 M00376 R09283 RC02480 ko00000,ko00001,ko00002,ko01000 Bacteria 1R43P@1224,2U1WN@28211,COG1804@1,COG1804@2 NA|NA|NA C acyl-CoA transferases carnitine dehydratase MAG.T12.39_01383 450851.PHZ_c3022 1.4e-83 316.2 Caulobacterales echA9 Bacteria 1MWZC@1224,2KFTA@204458,2TRYS@28211,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T12.39_01384 450851.PHZ_c1693 1.7e-150 538.9 Caulobacterales purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1MURG@1224,2KG2K@204458,2TR6G@28211,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase MAG.T12.39_01385 450851.PHZ_c1692 2.3e-178 631.7 Caulobacterales rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 1MURV@1224,2KF72@204458,2TSQM@28211,COG0349@1,COG0349@2 NA|NA|NA J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides MAG.T12.39_01386 1429916.X566_22740 5.4e-101 374.4 Bradyrhizobiaceae serA Bacteria 1MW1U@1224,2TSUU@28211,3JXSQ@41294,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MAG.T12.39_01387 450851.PHZ_c1691 6.1e-176 624.0 Caulobacterales ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1MV35@1224,2KFSF@204458,2TR1W@28211,COG0248@1,COG0248@2 NA|NA|NA FP Ppx GppA phosphatase MAG.T12.39_01388 450851.PHZ_c1690 0.0 1147.1 Caulobacterales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MUM3@1224,2KFTC@204458,2TRBP@28211,COG0855@1,COG0855@2 NA|NA|NA H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) MAG.T12.39_01389 450851.PHZ_c1689 8e-56 223.8 Caulobacterales hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 ko:K02313,ko:K10763 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1N4PG@1224,2KGSC@204458,2U96K@28211,COG0593@1,COG0593@2 NA|NA|NA L Belongs to the DnaA family MAG.T12.39_01390 450851.PHZ_c1688 4.9e-106 391.0 Caulobacterales ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 R11547,R11548 RC00064 ko00000,ko01000 Bacteria 1MW62@1224,2KF3D@204458,2TQY8@28211,COG2935@1,COG2935@2 NA|NA|NA O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate MAG.T12.39_01391 450851.PHZ_c1687 3.1e-116 424.9 Caulobacterales motB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101 ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1MW1Y@1224,2KEZ1@204458,2TTW2@28211,COG1360@1,COG1360@2 NA|NA|NA N PFAM OmpA MotB domain protein MAG.T12.39_01392 450851.PHZ_c1686 7e-116 423.7 Caulobacterales mmsB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 Bacteria 1MUGU@1224,2KFSV@204458,2TT50@28211,COG2084@1,COG2084@2 NA|NA|NA I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MAG.T12.39_01393 243365.CV_2875 9.6e-41 173.3 Neisseriales Bacteria 1PEQD@1224,2KTJW@206351,2WA5B@28216,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T12.39_01394 1122214.AQWH01000017_gene4630 2.4e-77 295.0 Alphaproteobacteria Bacteria 1RCZE@1224,2U5DQ@28211,COG1569@1,COG1569@2 NA|NA|NA S PIN domain MAG.T12.39_01395 991905.SL003B_3618 1.8e-62 245.4 Alphaproteobacteria Bacteria 1R8IB@1224,2U5Z2@28211,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain MAG.T12.39_01396 450851.PHZ_c1941 2.1e-134 486.1 Caulobacterales yheS_2 Bacteria 1MV25@1224,2KFP7@204458,2TSJ9@28211,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities MAG.T12.39_01397 78245.Xaut_4942 3.5e-23 114.4 Alphaproteobacteria Bacteria 1N3BI@1224,2UGP3@28211,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T12.39_01398 78245.Xaut_4941 4e-67 261.2 Alphaproteobacteria fic ko:K04095 ko00000,ko03036 Bacteria 1RAVF@1224,2U59F@28211,COG2184@1,COG2184@2 NA|NA|NA D Mobile mystery protein B MAG.T12.39_01399 450851.PHZ_c1682 7.6e-154 550.1 Caulobacterales hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MWMW@1224,2KEXR@204458,2TS3F@28211,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family MAG.T12.39_01400 1292034.OR37_03799 1.2e-163 582.8 Caulobacterales acdA 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUDR@1224,2KF6V@204458,2TQKE@28211,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T12.39_01401 450851.PHZ_c1679 5.7e-133 480.7 Caulobacterales hibch 3.1.2.4,4.2.1.17 ko:K01692,ko:K05605 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00013,M00032,M00087 R03026,R03045,R03158,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05064,R05595,R06411,R06412,R06942,R08093 RC00004,RC00014,RC00137,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU0B@1224,2KF3I@204458,2TQW3@28211,COG1024@1,COG1024@2 NA|NA|NA I enoyl-CoA hydratase MAG.T12.39_01402 1229204.AMYY01000023_gene2256 1.8e-111 409.1 Alphaproteobacteria mmsB 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 R05066 RC00099 ko00000,ko00001,ko01000 Bacteria 1RA7F@1224,2UVAZ@28211,COG2084@1,COG2084@2 NA|NA|NA I Belongs to the 3-hydroxyisobutyrate dehydrogenase family MAG.T12.39_01403 450851.PHZ_c2795 5.2e-202 710.3 Caulobacterales hemA 2.3.1.37,2.3.1.47 ko:K00643,ko:K00652 ko00260,ko00780,ko00860,ko01100,ko01110,map00260,map00780,map00860,map01100,map01110 M00123,M00573,M00577 R00830,R03210,R10124 RC00004,RC00039,RC02725,RC02815 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MVVH@1224,2KF5B@204458,2TQXI@28211,COG0156@1,COG0156@2 NA|NA|NA H 5-aminolevulinic acid synthase MAG.T12.39_01405 450851.PHZ_c3464 0.0 1274.2 Caulobacterales mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 Bacteria 1MUGX@1224,2KF1C@204458,2TQRR@28211,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity MAG.T12.39_01406 648885.KB316283_gene4209 2.2e-11 76.3 Methylobacteriaceae Bacteria 1JSBC@119045,1Q7XY@1224,2VE3D@28211,COG1708@1,COG1708@2 NA|NA|NA S Domain of unknown function (DUF4111) MAG.T12.39_01407 267608.RSp0780 8e-125 454.5 Proteobacteria Bacteria 1PARD@1224,COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity MAG.T12.39_01408 190650.CC_0011 6e-152 543.9 Caulobacterales dnaJ GO:0006457,GO:0008150,GO:0009987 ko:K03686 ko00000,ko03029,ko03110 Bacteria 1MVMS@1224,2KF8X@204458,2TRZ1@28211,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T12.39_01409 450851.PHZ_c0055 3.5e-306 1057.0 Caulobacterales dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1MVEN@1224,2KEZY@204458,2TR5H@28211,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein MAG.T12.39_01410 450851.PHZ_c0054 5e-42 177.6 Caulobacterales Bacteria 1R0EB@1224,2DRIM@1,2KK8W@204458,2TYPS@28211,33BYH@2 NA|NA|NA MAG.T12.39_01411 1382303.JPOM01000001_gene246 6.9e-95 354.0 Caulobacterales ysgA 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1MW7S@1224,2KGA7@204458,2TTPH@28211,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T12.39_01412 69395.JQLZ01000003_gene32 1.2e-145 523.1 Alphaproteobacteria Bacteria 1MVHG@1224,2TRA4@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_01413 1229204.AMYY01000028_gene858 1.1e-100 373.2 unclassified Alphaproteobacteria MA20_06030 Bacteria 1MW16@1224,2TRIG@28211,4BQ4Y@82117,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain MAG.T12.39_01414 450851.PHZ_c2620 3.8e-101 374.4 Caulobacterales yhhW ko:K06911 ko00000 Bacteria 1MVSW@1224,2KF5Q@204458,2TSR6@28211,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family MAG.T12.39_01415 190650.CC_0977 1.4e-151 543.1 Caulobacterales pepA 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUF9@1224,2KF6J@204458,2U2R6@28211,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T12.39_01416 450851.PHZ_c3499 6e-222 776.9 Caulobacterales purH 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUDQ@1224,2KFKT@204458,2TRMY@28211,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH MAG.T12.39_01417 450851.PHZ_c3501 1.8e-92 345.5 Caulobacterales rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUZM@1224,2KFA8@204458,2TQKR@28211,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family MAG.T12.39_01418 1449049.JONW01000006_gene2824 3.7e-137 495.0 Caulobacterales sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1MWPE@1224,2KFZY@204458,2TSIA@28211,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family MAG.T12.39_01419 450851.PHZ_c3503 2.9e-12 77.4 Caulobacterales Bacteria 1N7D3@1224,2KHD7@204458,2UF8M@28211,COG5508@1,COG5508@2 NA|NA|NA S Protein of unknown function (DUF1674) MAG.T12.39_01420 366602.Caul_4774 7.3e-84 317.0 Caulobacterales pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1MW2C@1224,2KG9V@204458,2TTB3@28211,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) MAG.T12.39_01421 450851.PHZ_c0052 9.2e-71 273.5 Caulobacterales ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1MX5T@1224,2KGDF@204458,2U59A@28211,COG2095@1,COG2095@2 NA|NA|NA U UPF0056 inner membrane protein MAG.T12.39_01422 450851.PHZ_c0051 1.7e-105 389.0 Caulobacterales ko:K07124 ko00000 Bacteria 1MWNZ@1224,2KFU5@204458,2VEWB@28211,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T12.39_01423 450851.PHZ_c0435 5.5e-69 267.7 Caulobacterales yafS Bacteria 1NA7K@1224,2KGJP@204458,2TT7T@28211,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase type 11 MAG.T12.39_01424 509190.Cseg_0398 5e-99 367.5 Caulobacterales gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MU8Q@1224,2KFV7@204458,2TSVS@28211,COG0491@1,COG0491@2 NA|NA|NA S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid MAG.T12.39_01425 450851.PHZ_c0433 5.2e-62 244.6 Caulobacterales Bacteria 1RJG7@1224,2ARAD@1,2KGQ5@204458,2UBC4@28211,31GKB@2 NA|NA|NA S Domain of unknown function (DUF4908) MAG.T12.39_01426 450851.PHZ_c0432 1.1e-111 409.5 Caulobacterales Bacteria 1MUEV@1224,2KG48@204458,2TRCF@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Acetoacetyl-CoA reductase MAG.T12.39_01427 450851.PHZ_c0431 8e-184 649.8 Caulobacterales phbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5G@1224,2KG3B@204458,2TQQ7@28211,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T12.39_01428 450851.PHZ_c0430 2.9e-63 248.4 Caulobacterales phaR Bacteria 1RHRC@1224,2KGAA@204458,2TQWQ@28211,COG5394@1,COG5394@2 NA|NA|NA S Polyhydroxyalkanoate synthesis repressor PhaR MAG.T12.39_01429 1449049.JONW01000005_gene1521 3.1e-08 64.7 Caulobacterales Bacteria 1NIG9@1224,2CH5I@1,2KHG0@204458,2UNAI@28211,33CGE@2 NA|NA|NA MAG.T12.39_01430 450851.PHZ_c0427 3.4e-103 381.3 Caulobacterales 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 1QVG6@1224,2KFY3@204458,2TWF3@28211,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T12.39_01431 450851.PHZ_c0426 1.9e-170 605.9 Caulobacterales Bacteria 1NMIZ@1224,2KEZT@204458,2TRS4@28211,COG1807@1,COG1807@2 NA|NA|NA M glycosyl transferase family 39 MAG.T12.39_01432 509190.Cseg_0532 1.1e-121 443.0 Caulobacterales GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.1.3.4,4.1.3.46 ko:K01640,ko:K18314 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090,R10674 RC00502,RC00503,RC01118,RC01205,RC01946 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUMX@1224,2KFEX@204458,2TT1R@28211,COG0119@1,COG0119@2 NA|NA|NA E Hydroxymethylglutaryl-CoA lyase MAG.T12.39_01433 450851.PHZ_c0424 4.8e-93 347.8 Caulobacterales wbbL ko:K07011 ko00000 Bacteria 1NM61@1224,2KG0N@204458,2TRZB@28211,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T12.39_01434 450851.PHZ_c0423 2.9e-292 1010.7 Caulobacterales thrS 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MUP2@1224,2KF0E@204458,2TQWI@28211,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) MAG.T12.39_01435 1121123.AUAO01000001_gene864 4.2e-27 127.1 Caulobacterales yidD ko:K08998 ko00000 Bacteria 1N6U4@1224,2KH5R@204458,2UFKH@28211,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane MAG.T12.39_01436 450851.PHZ_c0421 2.6e-50 204.9 Caulobacterales iscU ko:K04488 ko00000 Bacteria 1RDGB@1224,2KGTU@204458,2U74A@28211,COG0822@1,COG0822@2 NA|NA|NA C PFAM nitrogen-fixing NifU domain protein MAG.T12.39_01437 450851.PHZ_c0419 7.4e-36 157.1 Caulobacterales 4.4.1.22 ko:K03396 ko00680,ko01120,ko01200,map00680,map01120,map01200 R06982 RC00069,RC01707 ko00000,ko00001,ko01000 Bacteria 1N827@1224,2KH95@204458,2UHCT@28211,COG4891@1,COG4891@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport MAG.T12.39_01439 450851.PHZ_c0417 4.1e-94 350.9 Caulobacterales folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY3N@1224,2KFSC@204458,2TSZI@28211,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase MAG.T12.39_01440 450851.PHZ_c0416 1.6e-44 185.7 Caulobacterales hisI 3.5.4.19 ko:K01496 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04037 RC01055 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW67@1224,2KGN9@204458,2UCKH@28211,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP MAG.T12.39_01441 1123269.NX02_05230 1.3e-204 719.9 Sphingomonadales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QTXJ@1224,2KEEA@204457,2UQNF@28211,COG4773@1,COG4773@2 NA|NA|NA P TonB dependent receptor MAG.T12.39_01442 450851.PHZ_c0412 2.8e-182 645.2 Caulobacterales phoD 3.1.3.1 ko:K01077,ko:K01113,ko:K07004 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1MWAF@1224,2KFJ3@204458,2U0FQ@28211,COG3540@1,COG3540@2 NA|NA|NA P PhoD-like phosphatase MAG.T12.39_01443 190650.CC_0453 1.2e-116 426.4 Caulobacterales rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1MUBN@1224,2KEXS@204458,2TSBK@28211,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T12.39_01444 190650.CC_3098 1.2e-136 492.7 Caulobacterales rpoH GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141 ko:K03089 ko00000,ko03021 Bacteria 1MVWR@1224,2KFUM@204458,2TR9Q@28211,COG0568@1,COG0568@2 NA|NA|NA K RNA polymerase sigma factor RpoH MAG.T12.39_01445 1461694.ATO9_10345 3.1e-152 545.0 Oceanicola MA20_04500 Bacteria 1MV8Q@1224,2PD30@252301,2TRWW@28211,COG2124@1,COG2124@2 NA|NA|NA Q Cytochrome P450 MAG.T12.39_01446 450851.PHZ_c0976 3.1e-22 112.1 Caulobacterales Bacteria 1NB71@1224,2KHIJ@204458,2UI2W@28211,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T12.39_01447 59538.XP_005981807.1 1.7e-187 662.1 Mammalia Mammalia 38HVH@33154,3BCDJ@33208,3CTAB@33213,3JFRF@40674,481SY@7711,491WH@7742,COG0104@1,KOG1355@2759 NA|NA|NA F adenylosuccinate synthase activity MAG.T12.39_01448 450851.PHZ_c0406 5.9e-57 226.9 Caulobacterales ko:K06991 ko00000 Bacteria 1RD7C@1224,2KJCW@204458,2U78G@28211,COG3565@1,COG3565@2 NA|NA|NA S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T12.39_01449 450851.PHZ_c0405 3.4e-111 408.3 Caulobacterales 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVWJ@1224,2KF7B@204458,2TQN9@28211,COG1171@1,COG1171@2 NA|NA|NA E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit MAG.T12.39_01450 450851.PHZ_c0398 3.9e-229 800.8 Caulobacterales Bacteria 1MV86@1224,2KF25@204458,2TVJ5@28211,COG2234@1,COG2234@2 NA|NA|NA S peptidase MAG.T12.39_01451 450851.PHZ_c0396 1.2e-61 243.0 Caulobacterales Bacteria 1MYZN@1224,2KGID@204458,2UA87@28211,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T12.39_01452 190650.CC_0771 3.4e-109 401.7 Caulobacterales lipN ko:K01066 ko00000,ko01000 Bacteria 1NEXK@1224,2KFYS@204458,2U5X1@28211,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T12.39_01453 69395.JQLZ01000001_gene3340 8.8e-128 463.4 Caulobacterales MA20_32380 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MWRK@1224,2KG5N@204458,2TQMF@28211,COG0604@1,COG0604@2 NA|NA|NA C PFAM Alcohol dehydrogenase zinc-binding domain protein MAG.T12.39_01454 1121949.AQXT01000002_gene1610 2e-11 73.9 Hyphomonadaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1NGGS@1224,2UJCE@28211,43YT2@69657,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family MAG.T12.39_01455 366602.Caul_0641 9.4e-36 156.4 Caulobacterales rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1N6QY@1224,2KH2H@204458,2UFAB@28211,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme MAG.T12.39_01456 450851.PHZ_c0390 3.5e-199 701.4 Caulobacterales yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1MV5M@1224,2KF4R@204458,2TSTJ@28211,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins MAG.T12.39_01457 573065.Astex_1829 6.1e-83 313.9 Caulobacterales engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1MY3Z@1224,2KFST@204458,2U5E5@28211,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation MAG.T12.39_01458 450851.PHZ_c0388 1.7e-183 648.7 Caulobacterales 1.3.8.8 ko:K00255 ko00071,ko01100,ko01212,ko03320,map00071,map01100,map01212,map03320 M00087 R01279,R03777,R03857,R03990,R04751,R04754 RC00052 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUDR@1224,2KF2X@204458,2TR15@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM acyl-CoA dehydrogenase domain protein MAG.T12.39_01459 69395.JQLZ01000003_gene59 5.6e-167 594.0 Caulobacterales Bacteria 1MVAF@1224,2KF9Q@204458,2TTYC@28211,COG1228@1,COG1228@2 NA|NA|NA Q PFAM Amidohydrolase MAG.T12.39_01460 366602.Caul_4558 3.4e-137 494.6 Caulobacterales argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 1MU17@1224,2KFH4@204458,2TQQS@28211,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily MAG.T12.39_01461 450851.PHZ_c0385 1.1e-81 309.7 Caulobacterales ssm ko:K07025 ko00000 Bacteria 1PHPQ@1224,2KGKQ@204458,2TUDN@28211,COG1011@1,COG1011@2 NA|NA|NA S HAD-superfamily hydrolase, subfamily IA, variant 3 MAG.T12.39_01462 450851.PHZ_c0384 9e-105 386.7 Caulobacterales dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1MU0Y@1224,2KFUW@204458,2TS3H@28211,COG2171@1,COG2171@2 NA|NA|NA E Belongs to the transferase hexapeptide repeat family MAG.T12.39_01463 450851.PHZ_c0379 1.3e-167 595.9 Caulobacterales dapE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2485,iIT341.HP0212 Bacteria 1MW6G@1224,2KG1R@204458,2TT0J@28211,COG0624@1,COG0624@2 NA|NA|NA E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls MAG.T12.39_01464 450851.PHZ_c0378 9.9e-111 406.4 Caulobacterales truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1MUYI@1224,2KF4P@204458,2TR57@28211,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T12.39_01465 450851.PHZ_c0377 6.2e-123 447.2 Caulobacterales fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria 1MU4Q@1224,2KFHF@204458,2TSWX@28211,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus MAG.T12.39_01466 450851.PHZ_c0373 2.5e-73 281.6 Caulobacterales def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 1RA2P@1224,2KGBS@204458,2U797@28211,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions MAG.T12.39_01467 1292034.OR37_00655 3.4e-108 398.7 Caulobacterales rmuC ko:K09760 ko00000 Bacteria 1MWHV@1224,2KF4C@204458,2TTX6@28211,COG1322@1,COG1322@2 NA|NA|NA S RmuC family MAG.T12.39_01468 450851.PHZ_c0371 7.4e-85 320.1 Caulobacterales recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1MV9Q@1224,2KFR4@204458,2TRZM@28211,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO MAG.T12.39_01469 366602.Caul_0355 4.4e-77 295.8 Caulobacterales cybH Bacteria 1QWMC@1224,2KFWK@204458,2TSPB@28211,COG0474@1,COG0474@2 NA|NA|NA P Domain of unknown function (DUF4153) MAG.T12.39_01470 450851.PHZ_c0368 2.2e-220 771.9 Caulobacterales dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MVCK@1224,2KEY5@204458,2TRPB@28211,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity MAG.T12.39_01471 450851.PHZ_c0363 2.8e-131 474.9 Caulobacterales nudC 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 Bacteria 1QGCX@1224,2KG1N@204458,2TVMG@28211,COG2816@1,COG2816@2 NA|NA|NA L Belongs to the Nudix hydrolase family MAG.T12.39_01472 1449049.JONW01000005_gene1592 3.8e-111 407.9 Caulobacterales pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 ko:K03856,ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R00691,R01373,R01715,R01826 RC00360,RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2667 Bacteria 1MU60@1224,2KF3W@204458,2TSUT@28211,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase MAG.T12.39_01473 450851.PHZ_c0361 5.2e-91 340.9 Caulobacterales kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 Bacteria 1MUUU@1224,2KEZW@204458,2TUQM@28211,COG1212@1,COG1212@2 NA|NA|NA M Cytidylyltransferase MAG.T12.39_01474 450851.PHZ_c0360 1.3e-69 269.6 Caulobacterales cycM ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1RIDN@1224,2KGGW@204458,2U142@28211,COG3474@1,COG3474@2 NA|NA|NA C PFAM cytochrome c class I MAG.T12.39_01475 450851.PHZ_c0359 6.4e-82 310.8 Caulobacterales ykfC 3.4.14.13 ko:K20742,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1MW03@1224,2KFN6@204458,2TSFG@28211,COG0791@1,COG0791@2 NA|NA|NA M PFAM NLP P60 protein MAG.T12.39_01476 366602.Caul_4585 1.8e-155 555.8 Caulobacterales pepA 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUIN@1224,2KFPE@204458,2TSI6@28211,COG0260@1,COG0260@2 NA|NA|NA E Belongs to the peptidase M17 family MAG.T12.39_01478 450851.PHZ_c0355 1.7e-175 622.5 Caulobacterales MA20_25070 ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 1MWXB@1224,2KFQN@204458,2TSCV@28211,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like MAG.T12.39_01479 1038860.AXAP01000014_gene989 8.5e-98 363.6 Bradyrhizobiaceae Bacteria 1MXNQ@1224,2TUHP@28211,3JRVY@41294,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T12.39_01480 450851.PHZ_c3169 1.6e-50 206.1 Caulobacterales Bacteria 1MXEE@1224,2KGY6@204458,2U62V@28211,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T12.39_01481 450851.PHZ_c3174 7.2e-218 763.1 Caulobacterales MA20_31035 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU2V@1224,2KFYQ@204458,2TSK3@28211,COG1960@1,COG1960@2 NA|NA|NA C acyl-CoA dehydrogenase MAG.T12.39_01483 450851.PHZ_c3181 3.1e-41 174.1 Caulobacterales groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1MZ2X@1224,2KH3Y@204458,2U9AQ@28211,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T12.39_01485 1380355.JNIJ01000015_gene5921 1.7e-91 342.4 Bradyrhizobiaceae 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1NRB4@1224,2TU91@28211,3JUQK@41294,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T12.39_01487 450851.PHZ_c1157 5.4e-96 357.5 Caulobacterales Bacteria 1MW46@1224,2KH43@204458,2TUTU@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_01488 342113.DM82_4408 4.6e-192 677.6 Burkholderiaceae glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 Bacteria 1K3YU@119060,1MU6Y@1224,2VH8M@28216,COG0277@1,COG0277@2 NA|NA|NA C Glycolate oxidase subunit GlcD MAG.T12.39_01489 1123368.AUIS01000005_gene484 7.7e-93 347.4 Acidithiobacillales glcE ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001 Bacteria 1MVYV@1224,1RN4G@1236,2NC9T@225057,COG0277@1,COG0277@2 NA|NA|NA C FAD binding domain MAG.T12.39_01490 1192124.LIG30_4286 8.2e-107 394.0 Burkholderiaceae glcF GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001 iAPECO1_1312.glcF,iECABU_c1320.ECABU_c33760,iECIAI1_1343.ECIAI1_3119,iECIAI39_1322.ECIAI39_3465,iECNA114_1301.ECNA114_3053,iECP_1309.ECP_3055,iJN678.glcF,iJN746.PP_3747,iUTI89_1310.glcF,ic_1306.glcF Bacteria 1K0ER@119060,1MWTK@1224,2VISA@28216,COG0247@1,COG0247@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T12.39_01491 1090320.KB900605_gene2236 6.6e-149 533.9 Sphingomonadales Bacteria 1MVJC@1224,2K24U@204457,2TUVB@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T12.39_01493 69395.JQLZ01000008_gene2405 2.7e-33 148.7 Caulobacterales Bacteria 1N5X9@1224,2DC1J@1,2KK6P@204458,2VGQR@28211,32TYP@2 NA|NA|NA MAG.T12.39_01494 190650.CC_1588 2e-176 625.2 Caulobacterales tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 Bacteria 1MUCA@1224,2KFQA@204458,2TR87@28211,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) MAG.T12.39_01495 450851.PHZ_c1403 1.1e-131 476.5 Caulobacterales queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 ko:K00773,ko:K07568 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1MUH3@1224,2KEYT@204458,2TS0D@28211,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T12.39_01496 450851.PHZ_c1399 8.5e-73 279.6 Caulobacterales ppiB 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1R9ZQ@1224,2KGE2@204458,2U591@28211,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T12.39_01497 69395.JQLZ01000008_gene2399 3.8e-90 338.2 Caulobacterales 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1R62A@1224,2KG56@204458,2U3BZ@28211,COG0652@1,COG0652@2 NA|NA|NA M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T12.39_01498 450851.PHZ_c1397 4.2e-70 270.8 Caulobacterales coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1RD9F@1224,2KGDR@204458,2U74H@28211,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate MAG.T12.39_01499 450851.PHZ_c1396 0.0 1403.3 Caulobacterales gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1MUGG@1224,2KFAI@204458,2TSPQ@28211,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T12.39_01500 450851.PHZ_c1391 7.6e-72 276.6 Caulobacterales ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1RCWT@1224,2KGA6@204458,2U5BZ@28211,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism MAG.T12.39_01501 450851.PHZ_c1390 1.4e-28 132.5 Caulobacterales Bacteria 1N4RQ@1224,2DKS0@1,2KH1N@204458,2UE5H@28211,32UFH@2 NA|NA|NA MAG.T12.39_01502 450851.PHZ_c1389 2.2e-56 225.7 Caulobacterales Bacteria 1RHXC@1224,2B5IB@1,2KGUF@204458,2UAAA@28211,31YD2@2 NA|NA|NA MAG.T12.39_01503 450851.PHZ_c1388 1.6e-198 699.9 Caulobacterales Bacteria 1P31B@1224,2KFTR@204458,2U4EC@28211,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T12.39_01504 450851.PHZ_c1387 8.4e-87 327.0 Caulobacterales ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Bacteria 1MV1N@1224,2KG3Z@204458,2TUQQ@28211,COG1344@1,COG1344@2 NA|NA|NA N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella MAG.T12.39_01505 450851.PHZ_c1386 1.4e-09 68.9 Caulobacterales ko:K06603 ko00000,ko02035 Bacteria 1NM8P@1224,2EG0X@1,2KHEH@204458,2UM66@28211,339SY@2 NA|NA|NA MAG.T12.39_01506 450851.PHZ_c1385 3.5e-85 321.6 Caulobacterales fljL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Bacteria 1MV1N@1224,2KFYB@204458,2TUQQ@28211,COG1344@1,COG1344@2 NA|NA|NA N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella MAG.T12.39_01507 450851.PHZ_c1385 2.9e-79 302.0 Caulobacterales fljL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Bacteria 1MV1N@1224,2KFYB@204458,2TUQQ@28211,COG1344@1,COG1344@2 NA|NA|NA N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella MAG.T12.39_01508 1122132.AQYH01000019_gene410 1.1e-154 552.7 Rhizobiaceae 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXKV@1224,2TRM0@28211,4BA55@82115,COG0451@1,COG0451@2 NA|NA|NA GM dTDP-glucose 4-6-dehydratase MAG.T12.39_01509 509190.Cseg_1938 3.9e-36 157.5 Caulobacterales ko:K06602 ko00000,ko02035 Bacteria 1N1GT@1224,2KGYA@204458,2UCTU@28211,COG5442@1,COG5442@2 NA|NA|NA N PFAM flagellar FlaF family protein MAG.T12.39_01510 450851.PHZ_c1382 4.3e-55 220.7 Caulobacterales flbT ko:K06601 ko00000,ko02035 Bacteria 1RD3V@1224,2KGGZ@204458,2U7PK@28211,COG5443@1,COG5443@2 NA|NA|NA N Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK MAG.T12.39_01511 450851.PHZ_c1381 1.9e-168 599.4 Caulobacterales Bacteria 1MUZK@1224,2KFZX@204458,2TS0U@28211,COG0457@1,COG0457@2,COG0859@1,COG0859@2 NA|NA|NA M Tetratricopeptide repeat MAG.T12.39_01512 190650.CC_1455 8.3e-146 523.1 Caulobacterales moxR GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03924 ko00000,ko01000 Bacteria 1MV5I@1224,2KFG3@204458,2TRI8@28211,COG0714@1,COG0714@2 NA|NA|NA S AAA domain (dynein-related subfamily) MAG.T12.39_01513 450851.PHZ_c1376 8.1e-50 203.0 Caulobacterales Bacteria 1RJQD@1224,2D1BA@1,2KH16@204458,2U780@28211,32TAA@2 NA|NA|NA MAG.T12.39_01514 450851.PHZ_c1375 1e-105 389.8 Caulobacterales Bacteria 1RBYK@1224,2KGCR@204458,2U6WQ@28211,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein UspA MAG.T12.39_01515 509190.Cseg_1930 6.8e-83 313.5 Caulobacterales MA20_42120 ko:K06952 ko00000 Bacteria 1RACF@1224,2KF3T@204458,2TUK3@28211,COG1896@1,COG1896@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. MAG.T12.39_01516 450851.PHZ_c1373 1.2e-116 426.4 Caulobacterales MA20_42130 Bacteria 1MXHA@1224,2KEZQ@204458,2TQQU@28211,COG4111@1,COG4111@2 NA|NA|NA F belongs to the nudix hydrolase family MAG.T12.39_01517 1429916.X566_12620 8.6e-107 393.7 Bradyrhizobiaceae ko:K07119 ko00000 Bacteria 1MUC2@1224,2TQYM@28211,3JRF5@41294,COG2130@1,COG2130@2 NA|NA|NA S N-terminal domain of oxidoreductase MAG.T12.39_01518 190650.CC_1444 9.1e-127 459.9 Caulobacterales Bacteria 1NR7X@1224,2KG0P@204458,2TT68@28211,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase MAG.T12.39_01519 450851.PHZ_c1371 1e-22 113.2 Caulobacterales Bacteria 1P0G8@1224,2C63I@1,2KJ7I@204458,2UV9N@28211,347C8@2 NA|NA|NA MAG.T12.39_01520 59538.XP_005976087.1 1.1e-133 483.0 Cetartiodactyla Mammalia 38HSH@33154,3BBAE@33208,3CT0S@33213,3JAZF@40674,484K5@7711,49070@7742,4IZ07@91561,COG1816@1,KOG1097@2759 NA|NA|NA F adenosine deaminase MAG.T12.39_01521 1415754.JQMK01000013_gene90 3e-113 415.2 Alteromonadaceae 3.2.1.35 ko:K01197 ko00531,ko01100,map00531,map01100 M00076,M00077 R07824,R07825,R10905 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Bacteria 1QR2G@1224,1RZNM@1236,466IG@72275,COG3525@1,COG3525@2 NA|NA|NA G beta-N-acetylglucosaminidase MAG.T12.39_01522 1292034.OR37_00239 2.9e-167 594.7 Caulobacterales fabH 2.3.1.180,2.3.1.207 ko:K00648,ko:K16872 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iIT341.HP0202 Bacteria 1MU9N@1224,2KFNZ@204458,2TU94@28211,COG0332@1,COG0332@2 NA|NA|NA I PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III MAG.T12.39_01523 366602.Caul_2907 6.2e-131 474.2 Caulobacterales yhfN GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 1MUXT@1224,2KI6B@204458,2TVI9@28211,COG0501@1,COG0501@2 NA|NA|NA O CAAX prenyl protease N-terminal, five membrane helices MAG.T12.39_01524 450851.PHZ_c1366 0.0 1471.4 Caulobacterales ppdK 2.7.3.13,2.7.9.1 ko:K01006,ko:K22424 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU0R@1224,2KF8E@204458,2TR3C@28211,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family MAG.T12.39_01525 450851.PHZ_c1365 2.1e-241 842.0 Caulobacterales glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1MV2F@1224,2KFAD@204458,2TQKJ@28211,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit MAG.T12.39_01526 509190.Cseg_1639 8.2e-144 516.5 Caulobacterales glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1MVCJ@1224,2KFIR@204458,2TS2N@28211,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit MAG.T12.39_01527 509190.Cseg_1638 1.6e-22 112.8 Caulobacterales Bacteria 1RD06@1224,2KK5U@204458,2VFJR@28211,COG2335@1,COG2335@2 NA|NA|NA M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. MAG.T12.39_01528 450851.PHZ_c1361 4.2e-45 187.2 Caulobacterales glnK GO:0003674,GO:0005488,GO:0005515,GO:0006808,GO:0008150,GO:0042802,GO:0045848,GO:0048518,GO:0050789,GO:0065007 ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 1RGWK@1224,2KGQT@204458,2U952@28211,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family MAG.T12.39_01529 509190.Cseg_1635 1.6e-200 705.7 Caulobacterales amtB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015291,GO:0015292,GO:0015669,GO:0015670,GO:0015696,GO:0015893,GO:0016020,GO:0016021,GO:0019755,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098655 ko:K03320 ko00000,ko02000 1.A.11 iEcE24377_1341.EcE24377A_0487 Bacteria 1NR9F@1224,2KFYU@204458,2TT2J@28211,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter MAG.T12.39_01530 190650.CC_1336 2.7e-75 288.9 Caulobacterales ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1MVU3@1224,2KG6Q@204458,2TUFV@28211,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol MAG.T12.39_01531 450851.PHZ_c1358 2.5e-141 509.2 Caulobacterales Bacteria 1MYB8@1224,2KF7J@204458,2TQV5@28211,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeats MAG.T12.39_01532 59538.XP_005985513.1 1.2e-249 869.0 Cetartiodactyla Mammalia 38H8R@33154,3BH2N@33208,3CWV6@33213,3J1P9@40674,484PU@7711,48WYX@7742,4IYEG@91561,COG2440@1,KOG2415@2759 NA|NA|NA C Electron transfer flavoprotein-ubiquinone oxidoreductase MAG.T12.39_01533 69395.JQLZ01000005_gene3682 1.2e-77 296.6 Caulobacterales udgA 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWX1@1224,2KFNB@204458,2TT4Q@28211,COG1573@1,COG1573@2 NA|NA|NA L uracil-DNA glycosylase MAG.T12.39_01534 450851.PHZ_c1353 1e-07 63.5 Caulobacterales 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 1NGT6@1224,2KJMB@204458,2UJKZ@28211,COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T12.39_01535 1219031.BBJR01000042_gene2844 8.3e-74 284.6 Comamonadaceae clsC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 ko:K06132 ko00564,ko01100,map00564,map01100 R11062 RC00017 ko00000,ko00001,ko01000 Bacteria 1MUDJ@1224,2VHSI@28216,4AAIW@80864,COG1502@1,COG1502@2 NA|NA|NA I PFAM Phospholipase D Transphosphatidylase MAG.T12.39_01536 450851.PHZ_c1986 9.3e-224 782.7 Caulobacterales aroH GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iIT341.HP0134 Bacteria 1MUWF@1224,2KEXD@204458,2TR0E@28211,COG3200@1,COG3200@2 NA|NA|NA E phospho-2-dehydro-3-deoxyheptonate aldolase MAG.T12.39_01537 450851.PHZ_c1987 3.2e-71 275.8 Caulobacterales ko:K16567 ko00000 Bacteria 1N8BD@1224,2KGSZ@204458,2UG6G@28211,COG3307@1,COG3307@2 NA|NA|NA M O-antigen MAG.T12.39_01538 450851.PHZ_c1988 4.3e-165 587.8 Caulobacterales gor GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1MU2Z@1224,2KFW1@204458,2TQS7@28211,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family MAG.T12.39_01539 1207058.L53_09775 2.7e-80 306.2 Hyphomonadaceae dtpT ko:K03305 ko00000 2.A.17 Bacteria 1MW6W@1224,2U15C@28211,43ZHK@69657,COG3104@1,COG3104@2 NA|NA|NA P POT family MAG.T12.39_01540 450851.PHZ_c1989 4.8e-88 330.9 Caulobacterales rpiA 2.7.1.12,2.7.1.15,5.3.1.6 ko:K00851,ko:K00852,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01051,R01056,R01737,R02750 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVGR@1224,2KF95@204458,2TU68@28211,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate MAG.T12.39_01541 450851.PHZ_c1990 2.5e-165 588.6 Caulobacterales glmU 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPH@1224,2KF9G@204458,2TQPS@28211,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain MAG.T12.39_01542 450851.PHZ_c1991 6.4e-72 277.3 Caulobacterales gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1RDDY@1224,2KGHI@204458,2U79T@28211,COG0546@1,COG0546@2 NA|NA|NA G Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress MAG.T12.39_01543 450851.PHZ_c0057 7.5e-208 730.3 Alphaproteobacteria pvaA 1.1.2.6,2.7.11.1,3.1.4.53 ko:K03651,ko:K05889,ko:K12132 ko00230,ko02025,map00230,map02025 R00191,R03136 RC00296 ko00000,ko00001,ko01000,ko01001 Bacteria 1PIDE@1224,2TTS3@28211,COG1520@1,COG1520@2,COG2010@1,COG2010@2,COG4993@1,COG4993@2 NA|NA|NA C PQQ-like domain MAG.T12.39_01545 1282876.BAOK01000001_gene1319 2.7e-83 315.8 Alphaproteobacteria Bacteria 1RBGZ@1224,2U82S@28211,COG4638@1,COG4638@2 NA|NA|NA P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit MAG.T12.39_01546 1245469.S58_37940 1.9e-23 115.5 Bradyrhizobiaceae yjbI ko:K06886 ko00000 Bacteria 1RH21@1224,2VGD2@28211,3JYBS@41294,COG2346@1,COG2346@2 NA|NA|NA S Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MAG.T12.39_01547 525373.HMPREF0766_11664 3.7e-16 91.7 Sphingobacteriia Bacteria 1IZ1R@117747,2ERA8@1,33IVV@2,4P6D2@976 NA|NA|NA MAG.T12.39_01548 491916.RHECIAT_CH0000808 1.7e-116 427.9 Rhizobiaceae zapA 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1MU7T@1224,2TRVY@28211,4B9MG@82115,COG2931@1,COG2931@2 NA|NA|NA Q COG2931 RTX toxins and related Ca2 -binding proteins MAG.T12.39_01549 946362.XP_004989202.1 1.5e-32 147.1 Eukaryota Eukaryota COG0451@1,KOG1502@2759 NA|NA|NA GM dihydrokaempferol 4-reductase activity MAG.T12.39_01550 1123256.KB907925_gene1110 3e-19 101.7 Xanthomonadales Bacteria 1ND3X@1224,1SD5R@1236,1XBKZ@135614,2DNX2@1,32ZMB@2 NA|NA|NA S Protein of unknown function (DUF2834) MAG.T12.39_01551 450851.PHZ_c0959 8.3e-91 340.1 Caulobacterales Bacteria 1R8HN@1224,2KIT0@204458,2U0TG@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T12.39_01552 1219045.BV98_001398 8e-210 736.5 Sphingomonadales gltD 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iSB619.SA_RS02450 Bacteria 1MU2H@1224,2K21U@204457,2TSE2@28211,COG0493@1,COG0493@2 NA|NA|NA E Glutamate synthase MAG.T12.39_01553 110319.CF8_2503 0.0 1275.0 Propionibacteriales gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2GN09@201174,4DP8G@85009,COG0067@1,COG0067@2,COG0069@1,COG0069@2 NA|NA|NA E GXGXG motif MAG.T12.39_01554 450851.PHZ_c0624 1.7e-76 292.4 Caulobacterales Bacteria 1RANW@1224,2KHIR@204458,2U66N@28211,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family MAG.T12.39_01555 450851.PHZ_c2747 1.3e-95 356.7 Caulobacterales bphP 2.7.13.3,3.1.3.3 ko:K07315,ko:K11527,ko:K20974 ko02020,ko02025,map02020,map02025 M00820 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021 Bacteria 1NC9X@1224,2KK7A@204458,2TWEX@28211,COG0784@1,COG0784@2,COG4251@1,COG4251@2 NA|NA|NA T response regulator MAG.T12.39_01556 450851.PHZ_c2745 0.0 1160.2 Caulobacterales Bacteria 1R479@1224,2KFVU@204458,2TV3V@28211,COG1629@1,COG1629@2,COG4774@1,COG4774@2 NA|NA|NA P TonB-dependent receptor MAG.T12.39_01557 450851.PHZ_c1979 5.4e-142 511.5 Alphaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1RBA9@1224,2U0CH@28211,COG1629@1,COG4771@2 NA|NA|NA P COG1629 Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_01558 450851.PHZ_c1979 2.5e-63 248.8 Alphaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1RBA9@1224,2U0CH@28211,COG1629@1,COG4771@2 NA|NA|NA P COG1629 Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_01559 69395.JQLZ01000003_gene473 1.6e-97 362.5 Caulobacterales queC 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 R09978 RC00959 ko00000,ko00001,ko01000,ko03016 Bacteria 1MU5V@1224,2KFCC@204458,2TU7F@28211,COG0603@1,COG0603@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) MAG.T12.39_01560 450851.PHZ_c2743 8.6e-92 343.2 Caulobacterales queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 Bacteria 1MUJ2@1224,2KG37@204458,2TU1S@28211,COG0602@1,COG0602@2 NA|NA|NA H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds MAG.T12.39_01561 450851.PHZ_c2742 1.7e-47 195.3 Caulobacterales queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1RJYR@1224,2KGTE@204458,2UBK1@28211,COG0720@1,COG0720@2 NA|NA|NA H 6-pyruvoyl tetrahydropterin synthase MAG.T12.39_01562 190650.CC_1777 2.4e-90 338.6 Caulobacterales sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 1MVW2@1224,2KGAC@204458,2TQYJ@28211,COG0605@1,COG0605@2 NA|NA|NA C Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T12.39_01563 366602.Caul_3961 6.1e-178 630.2 Caulobacterales aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iIT341.HP0663,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Bacteria 1MU98@1224,2KF6T@204458,2TQY2@28211,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system MAG.T12.39_01564 317655.Sala_2285 1.6e-83 315.8 Sphingomonadales MA20_23640 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1MW7S@1224,2KDGA@204457,2TTPH@28211,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T12.39_01565 450851.PHZ_c2738 1.4e-84 319.3 Caulobacterales pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1NZUU@1224,2KFPI@204458,2TT1U@28211,COG0259@1,COG0259@2 NA|NA|NA H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) MAG.T12.39_01566 1449049.JONW01000008_gene310 3.5e-144 518.5 Caulobacterales GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 ko:K07028 ko00000 Bacteria 1MU9M@1224,2KG4B@204458,2TQJN@28211,COG0645@1,COG0645@2,COG2187@1,COG2187@2 NA|NA|NA S Phosphotransferase MAG.T12.39_01567 983920.Y88_2544 3e-50 204.9 Sphingomonadales 5.3.4.1 ko:K01829,ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 1RJK1@1224,2K4FP@204457,2UAQK@28211,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T12.39_01568 450851.PHZ_c0610 2.6e-160 571.6 Caulobacterales 1.4.3.3 ko:K00273 ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146 R00366,R02457,R02894,R02923,R04221,R07400 RC00006,RC00018,RC00135 ko00000,ko00001,ko01000 Bacteria 1N0QB@1224,2KF8B@204458,2TU6K@28211,COG0579@1,COG0579@2 NA|NA|NA S FAD dependent oxidoreductase MAG.T12.39_01569 450851.PHZ_c0604 1.3e-71 275.8 Caulobacterales ko:K03719,ko:K05800 ko00000,ko03000,ko03036 Bacteria 1RHP2@1224,2KGAI@204458,2U6ES@28211,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T12.39_01570 190650.CC_2908 1.8e-48 199.1 Caulobacterales pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325 Bacteria 1RCZ7@1224,2KGJ0@204458,2TUI7@28211,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T12.39_01571 450851.PHZ_c0599 7.3e-288 996.1 Caulobacterales uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1MV38@1224,2KFEF@204458,2TT32@28211,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision MAG.T12.39_01572 391600.ABRU01000009_gene3302 8.1e-32 142.9 Caulobacterales MA20_23570 ko:K03892 ko00000,ko03000 Bacteria 1QVFX@1224,2KH4Z@204458,2TWEG@28211,COG0640@1,COG0640@2 NA|NA|NA K Winged helix DNA-binding domain MAG.T12.39_01573 69395.JQLZ01000002_gene1291 6.3e-31 141.0 Caulobacterales Bacteria 1NE2U@1224,2EATF@1,2KHCS@204458,2UG2E@28211,334V8@2 NA|NA|NA MAG.T12.39_01574 450851.PHZ_c0597 6.2e-212 743.8 Caulobacterales ko:K00666 ko00000,ko01000,ko01004 Bacteria 1MWSD@1224,2KFP4@204458,2TU6Y@28211,COG0318@1,COG0318@2 NA|NA|NA IQ synthetase MAG.T12.39_01575 1280950.HJO_16837 1.3e-42 180.3 Hyphomonadaceae 5.2.1.8 ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 1R4ZR@1224,2U874@28211,43YY3@69657,COG0760@1,COG0760@2 NA|NA|NA O COG0760 Parvulin-like peptidyl-prolyl isomerase MAG.T12.39_01576 1280948.HY36_13700 1.9e-227 795.4 Alphaproteobacteria Bacteria 1MU3Q@1224,28HMZ@1,2TSGX@28211,2Z7WD@2 NA|NA|NA S Protein of unknown function (DUF3604) MAG.T12.39_01577 1280950.HJO_16832 6.7e-63 248.1 Hyphomonadaceae Bacteria 1MV6Z@1224,2TSX2@28211,43Y5W@69657,COG2370@1,COG2370@2 NA|NA|NA O HupE / UreJ protein MAG.T12.39_01578 450851.PHZ_c0556 3e-170 604.7 Caulobacterales Bacteria 1R4UN@1224,2KJJ3@204458,2U2QQ@28211,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase MAG.T12.39_01579 509190.Cseg_0296 1.2e-58 232.6 Caulobacterales MA20_20905 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1MU0H@1224,2KGDK@204458,2U6ZN@28211,COG0678@1,COG0678@2 NA|NA|NA O Redoxin domain protein MAG.T12.39_01580 450851.PHZ_c0553 2.6e-55 221.9 Caulobacterales MA20_18155 ko:K07735 ko00000,ko03000 Bacteria 1RCXM@1224,2KGFN@204458,2TTX4@28211,COG1678@1,COG1678@2 NA|NA|NA K Belongs to the UPF0301 (AlgH) family MAG.T12.39_01581 450851.PHZ_c0552 7.7e-233 813.1 Caulobacterales 3.1.4.52 ko:K13245 ko04112,map04112 R08991 RC00296 ko00000,ko00001,ko01000 Bacteria 1MU2C@1224,2KF2A@204458,2TQS3@28211,COG5001@1,COG5001@2 NA|NA|NA T Diguanylate cyclase MAG.T12.39_01582 450851.PHZ_c0551 1.1e-78 299.7 Caulobacterales rimJ 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1MVG4@1224,2KGBF@204458,2TUIK@28211,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T12.39_01583 450851.PHZ_c0550 2.4e-120 439.1 Caulobacterales pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MVST@1224,2KF1S@204458,2TR39@28211,COG0612@1,COG0612@2 NA|NA|NA S PFAM peptidase M16 domain protein MAG.T12.39_01584 450851.PHZ_c0549 1.5e-165 589.3 Caulobacterales thrC GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUWQ@1224,2KF1H@204458,2TT0D@28211,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase MAG.T12.39_01585 450851.PHZ_c0548 2.5e-69 268.9 Caulobacterales surf-1 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 1N5JU@1224,2KGZ3@204458,2UCJU@28211,COG3346@1,COG3346@2 NA|NA|NA S SURF1-like protein MAG.T12.39_01586 450851.PHZ_c0547 4.8e-47 193.7 Caulobacterales Bacteria 1N0WU@1224,2KH29@204458,2UCE7@28211,COG5349@1,COG5349@2 NA|NA|NA S Protein of unknown function (DUF983) MAG.T12.39_01587 450851.PHZ_c0546 1.8e-132 478.8 Caulobacterales ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 iJN678.ctaE Bacteria 1MUCK@1224,2KF31@204458,2TQWA@28211,COG1845@1,COG1845@2 NA|NA|NA C Cytochrome c oxidase subunit III MAG.T12.39_01588 69395.JQLZ01000004_gene730 8.6e-65 253.4 Caulobacterales ctaG GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 ko00000,ko00001,ko00002,ko03029 3.D.4.8 Bacteria 1RDTU@1224,2KGQI@204458,2U6ZT@28211,COG3175@1,COG3175@2 NA|NA|NA O Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I MAG.T12.39_01590 450851.PHZ_c0544 1.4e-138 499.2 Caulobacterales ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Bacteria 1MW3S@1224,2KFKK@204458,2TRD8@28211,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group MAG.T12.39_01591 450851.PHZ_c0543 3.2e-287 993.8 Caulobacterales ctaD GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 1MU7S@1224,2KFEV@204458,2TQP1@28211,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B MAG.T12.39_01592 450851.PHZ_c0542 5.3e-117 427.6 Caulobacterales ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1MWHZ@1224,2KFDC@204458,2TRK6@28211,COG1622@1,COG1622@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T12.39_01593 450851.PHZ_c0541 2.9e-220 771.2 Caulobacterales tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K03568 ko00000,ko01002 Bacteria 1MUSK@1224,2KG2M@204458,2TRSR@28211,COG0312@1,COG0312@2 NA|NA|NA S Modulator of DNA gyrase MAG.T12.39_01594 391600.ABRU01000056_gene586 2.6e-232 811.6 Caulobacterales ko:K03305 ko00000 2.A.17 Bacteria 1MW6W@1224,2KFSD@204458,2U15C@28211,COG3104@1,COG3104@2 NA|NA|NA E amino acid peptide transporter MAG.T12.39_01595 450851.PHZ_c0536 4.7e-183 647.5 Caulobacterales gshA 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU47@1224,2KFBZ@204458,2TRPT@28211,COG3572@1,COG3572@2 NA|NA|NA H glutamate--cysteine ligase MAG.T12.39_01596 450851.PHZ_c0535 2.2e-67 262.3 Caulobacterales rsmE 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1MXCU@1224,2KFXV@204458,2TS0N@28211,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit MAG.T12.39_01597 1044.EH31_04265 1.3e-13 84.0 Proteobacteria Bacteria 1NC3D@1224,COG0596@1,COG0596@2 NA|NA|NA S Alpha beta hydrolase MAG.T12.39_01598 190650.CC_3416 2.9e-89 335.1 Caulobacterales ppk2 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MVE2@1224,2KFZA@204458,2TSU8@28211,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T12.39_01599 1254432.SCE1572_48865 7e-151 540.4 Myxococcales ycaQ ko:K09927 ko00000 Bacteria 1N40B@1224,2X2RH@28221,2YVNV@29,437I2@68525,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain MAG.T12.39_01600 450851.PHZ_c0847 3.8e-68 265.0 Caulobacterales prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1QVGW@1224,2KIJD@204458,2UHE0@28211,COG2264@1,COG2264@2 NA|NA|NA J Methyltransferase small domain MAG.T12.39_01601 450851.PHZ_c0528 3.9e-238 830.9 Caulobacterales exsA ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1MUBM@1224,2KFHI@204458,2TQMR@28211,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T12.39_01602 366602.Caul_0359 6.2e-118 430.6 Caulobacterales ubiA 2.5.1.39 ko:K03179,ko:K06125 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117,M00128 R05000,R05615,R05616,R07273 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1MV4Q@1224,2KFQ0@204458,2TT3I@28211,COG0382@1,COG0382@2 NA|NA|NA H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate MAG.T12.39_01603 1280949.HAD_07965 6e-105 387.9 Alphaproteobacteria Bacteria 1MY5H@1224,2TTRR@28211,COG2124@1,COG2124@2 NA|NA|NA Q cytochrome P450 MAG.T12.39_01604 509190.Cseg_3951 1.3e-58 233.0 Caulobacterales yiaD Bacteria 1MYBP@1224,2KGBA@204458,2U787@28211,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T12.39_01605 450851.PHZ_c0530 2.3e-117 428.7 Caulobacterales MA20_28095 Bacteria 1MUHK@1224,2KG5X@204458,2TSTR@28211,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T12.39_01606 450851.PHZ_c0531 3.7e-93 347.8 Caulobacterales GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 Bacteria 1N9VC@1224,2KFN9@204458,2TV6N@28211,COG3897@1,COG3897@2 NA|NA|NA S L11 methyltransferase MAG.T12.39_01607 450851.PHZ_c0526 3.5e-61 242.7 Proteobacteria 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1RHEF@1224,COG0265@1,COG0265@2 NA|NA|NA O Trypsin MAG.T12.39_01608 450851.PHZ_c0523 1.8e-248 865.1 Caulobacterales ggt_1 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUV6@1224,2KF0J@204458,2TQWP@28211,COG0405@1,COG0405@2 NA|NA|NA E gamma-glutamyltranspeptidase MAG.T12.39_01609 366602.Caul_3996 4.3e-111 407.9 Caulobacterales ko:K07486 ko00000 Bacteria 1MXKJ@1224,2KHSD@204458,2U2G6@28211,COG3547@1,COG3547@2 NA|NA|NA L Transposase MAG.T12.39_01610 1300345.LF41_2916 9.5e-24 117.5 Gammaproteobacteria Bacteria 1R8VC@1224,1S5UD@1236,2C3WA@1,2Z8P1@2 NA|NA|NA MAG.T12.39_01611 366602.Caul_3952 4.9e-225 786.9 Caulobacterales 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1MU6V@1224,2KI74@204458,2TTPD@28211,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase MAG.T12.39_01612 1292034.OR37_02738 5e-172 610.5 Caulobacterales ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1MUYW@1224,2KHP0@204458,2TSUZ@28211,COG0687@1,COG0687@2 NA|NA|NA E Required for the activity of the bacterial periplasmic transport system of putrescine MAG.T12.39_01613 190650.CC_3136 3.9e-130 471.1 Caulobacterales ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1MVGM@1224,2KGT2@204458,2TSFD@28211,COG1176@1,COG1176@2 NA|NA|NA P PFAM binding-protein-dependent transport systems inner membrane component MAG.T12.39_01614 509190.Cseg_0819 7.6e-131 473.4 Caulobacterales potC ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1MVC5@1224,2KGW4@204458,2TRRJ@28211,COG1177@1,COG1177@2 NA|NA|NA P Spermidine putrescine ABC transporter, permease MAG.T12.39_01615 69395.JQLZ01000003_gene456 5.7e-179 633.6 Caulobacterales potA 3.6.3.31 ko:K11072,ko:K11076 ko02010,map02010 M00299,M00300 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1,3.A.1.11.2 Bacteria 1MU3I@1224,2KG68@204458,2TQMJ@28211,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system MAG.T12.39_01616 366602.Caul_3947 1.5e-103 382.5 Caulobacterales ko:K07010 ko00000,ko01002 Bacteria 1MV8E@1224,2KH8J@204458,2TSU3@28211,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 MAG.T12.39_01617 1449049.JONW01000005_gene1017 4.1e-243 847.0 Caulobacterales 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 Bacteria 1MU2N@1224,2KIGP@204458,2TQND@28211,COG0161@1,COG0161@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T12.39_01618 366602.Caul_3944 2.7e-223 781.2 Caulobacterales glnA1 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1MU6V@1224,2KIF1@204458,2TRCP@28211,COG0174@1,COG0174@2 NA|NA|NA E Belongs to the glutamine synthetase family MAG.T12.39_01619 1449049.JONW01000005_gene1015 6.8e-144 517.3 Caulobacterales ordL ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVGP@1224,2KI27@204458,2TRX9@28211,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase MAG.T12.39_01620 450851.PHZ_c2981 2e-303 1047.7 Caulobacterales lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1MVZA@1224,2KFIM@204458,2TR3H@28211,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner MAG.T12.39_01621 1174684.EBMC1_03774 6.2e-10 70.5 Sphingomonadales Bacteria 1NEAF@1224,2K7RK@204457,2UIAX@28211,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_01622 1449049.JONW01000007_gene3870 4.4e-38 163.7 Caulobacterales rpoZ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1N6TX@1224,2KGPE@204458,2U9BQ@28211,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits MAG.T12.39_01623 450851.PHZ_c1880 0.0 1178.3 Caulobacterales spoT GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475 Bacteria 1MU44@1224,2KFDI@204458,2TQNY@28211,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance MAG.T12.39_01624 450851.PHZ_c0937 1.2e-130 472.6 Caulobacterales 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 R05320 RC01331 ko00000,ko00001,ko01000 Bacteria 1MV5K@1224,2KIUC@204458,2TQTZ@28211,COG2175@1,COG2175@2 NA|NA|NA Q PFAM Taurine catabolism dioxygenase TauD TfdA MAG.T12.39_01625 1267005.KB911258_gene575 1.1e-97 363.2 Hyphomicrobiaceae eamA GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015562,GO:0015711,GO:0015804,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0032973,GO:0033228,GO:0034220,GO:0042883,GO:0044425,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0140115,GO:1903712,GO:1903825,GO:1905039 ko:K03298,ko:K15268 ko00000,ko02000 2.A.7.3,2.A.7.3.2 iECIAI39_1322.ECIAI39_1835 Bacteria 1MVKG@1224,2TVQG@28211,3N6ZR@45401,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T12.39_01626 450851.PHZ_c1877 1.2e-92 345.9 Caulobacterales pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 Bacteria 1RIC5@1224,2KFMB@204458,2TUX2@28211,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) MAG.T12.39_01627 391600.ABRU01000041_gene2534 1.6e-84 319.3 Caulobacterales pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 iAF1260.b2564,iAF987.Gmet_1885,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 Bacteria 1MU9W@1224,2KFBV@204458,2TTTF@28211,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate MAG.T12.39_01628 450851.PHZ_c1875 1.4e-55 222.2 Caulobacterales acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1MZBF@1224,2KH1G@204458,2U77S@28211,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein MAG.T12.39_01629 450851.PHZ_c1871 4.2e-85 321.2 Caulobacterales lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1MXUF@1224,2KFBG@204458,2TR9N@28211,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family MAG.T12.39_01630 450851.PHZ_c1870 2.5e-65 255.4 Caulobacterales rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1MUQ6@1224,2KGIJ@204458,2TTIA@28211,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism MAG.T12.39_01631 59538.XP_005969861.1 8.1e-131 473.4 Cetartiodactyla Mammalia 39S0I@33154,3BJ0J@33208,3CYG8@33213,3J937@40674,47ZIG@7711,49273@7742,4IZKU@91561,COG1159@1,KOG1423@2759 NA|NA|NA DT Era like 12S mitochondrial rRNA chaperone 1 MAG.T12.39_01632 450851.PHZ_c1867 3.1e-101 374.8 Caulobacterales recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 ko:K03474,ko:K03584 ko00750,ko01100,ko03440,map00750,map01100,map03440 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1MVEJ@1224,2KFSQ@204458,2TTYW@28211,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination MAG.T12.39_01633 59538.XP_005969860.1 0.0 1158.7 Metazoa Metazoa 39WG1@33154,3BNSE@33208,COG0187@1,KOG0355@2759 NA|NA|NA B DNA gyrase C-terminal domain, beta-propeller MAG.T12.39_01634 450851.PHZ_c1860 2.7e-164 585.1 Caulobacterales Bacteria 1MVPR@1224,2KIBF@204458,2TRWZ@28211,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T12.39_01635 59538.XP_005975961.1 1.5e-295 1021.5 Cetartiodactyla Mammalia 38HAY@33154,3B9K1@33208,3CVA4@33213,3J3E9@40674,489DP@7711,497DG@7742,4J4U1@91561,COG0173@1,KOG2411@2759 NA|NA|NA J aspartate--tRNA ligase MAG.T12.39_01637 1246459.KB898361_gene5576 8.6e-16 89.7 Rhizobiaceae Bacteria 1NCM1@1224,2EEKZ@1,2UFHE@28211,338ET@2,4BF3M@82115 NA|NA|NA MAG.T12.39_01638 450851.PHZ_c1855 9.1e-174 617.5 Caulobacterales nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1MUJ8@1224,2KF6U@204458,2TS2I@28211,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen MAG.T12.39_01639 366602.Caul_2561 1.9e-60 238.4 Caulobacterales MA20_29090 1.6.99.3 ko:K00356 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1RHS3@1224,2KGNZ@204458,2U95G@28211,COG3761@1,COG3761@2 NA|NA|NA C NADH ubiquinone oxidoreductase 17.2 kD subunit MAG.T12.39_01640 450851.PHZ_c1853 7.9e-43 180.6 Caulobacterales ko:K07465 ko00000 Bacteria 1RHI7@1224,2KGXI@204458,2UBR9@28211,COG4765@1,COG4765@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2155) MAG.T12.39_01641 1121123.AUAO01000003_gene2507 3.3e-54 218.4 Caulobacterales aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 ko:K00684 R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 Bacteria 1R9W8@1224,2KG9S@204458,2U59K@28211,COG2360@1,COG2360@2 NA|NA|NA O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine MAG.T12.39_01642 450851.PHZ_c1851 3.6e-228 797.3 Caulobacterales accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4H@1224,2KFCN@204458,2U25Z@28211,COG0439@1,COG0439@2 NA|NA|NA I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism MAG.T12.39_01643 450851.PHZ_c1850 1.1e-43 183.0 Caulobacterales accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.3.1.12 ko:K00627,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1RCXA@1224,2KGUG@204458,2U93Y@28211,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA MAG.T12.39_01644 366602.Caul_2567 7.4e-17 92.8 Caulobacterales thiS GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149,ko:K03154 ko00730,ko01100,ko04122,map00730,map01100,map04122 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 1NG8E@1224,2KH79@204458,2UG5I@28211,COG2104@1,COG2104@2 NA|NA|NA H thiamine biosynthesis protein ThiS MAG.T12.39_01645 450851.PHZ_c1847 6.5e-121 440.3 Caulobacterales thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 1N0N5@1224,2KFEW@204458,2TSXS@28211,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S MAG.T12.39_01646 59538.XP_005973943.1 3.5e-95 354.8 Eukaryota Eukaryota COG1028@1,KOG0725@2759 NA|NA|NA IQ oxidation-reduction process MAG.T12.39_01648 450851.PHZ_c1845 7.3e-174 617.1 Alphaproteobacteria GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R01298 RC00046 ko00000,ko00001,ko01000 Bacteria 1QNRY@1224,2TWKF@28211,COG0654@1,COG0654@2 NA|NA|NA CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases MAG.T12.39_01649 450851.PHZ_c1844 1.3e-59 236.5 Caulobacterales dsbA Bacteria 1MY3H@1224,2KGNC@204458,2TTXR@28211,COG1651@1,COG1651@2 NA|NA|NA O DSBA-like thioredoxin domain MAG.T12.39_01650 450851.PHZ_c1843 5.8e-165 587.4 Caulobacterales MA20_29180 Bacteria 1MVFV@1224,2KEZZ@204458,2TTV2@28211,COG4783@1,COG4783@2 NA|NA|NA S Peptidase M48 MAG.T12.39_01651 450851.PHZ_c1842 4.1e-241 841.3 Caulobacterales rne 3.1.26.12 ko:K08300 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 1MV65@1224,2KFBU@204458,2TRX2@28211,COG1530@1,COG1530@2 NA|NA|NA J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs MAG.T12.39_01652 450851.PHZ_c1841 9.2e-98 363.6 Caulobacterales amiC 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1MUQK@1224,2KF5N@204458,2U0K2@28211,COG0860@1,COG0860@2 NA|NA|NA M cell wall hydrolase MAG.T12.39_01653 1292034.OR37_00209 1.2e-308 1065.4 Caulobacterales mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1MU5A@1224,2KFW7@204458,2USBB@28211,COG5009@1,COG5009@2 NA|NA|NA M penicillin-binding protein 1A MAG.T12.39_01654 450851.PHZ_c1839 1.7e-175 622.1 Caulobacterales prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1MUAW@1224,2KEZ8@204458,2TR9V@28211,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA MAG.T12.39_01655 190650.CC_1873 3.2e-35 154.8 Caulobacterales Bacteria 1MZN0@1224,2KGZV@204458,2U5DW@28211,COG1664@1,COG1664@2 NA|NA|NA M Polymer-forming cytoskeletal MAG.T12.39_01656 450851.PHZ_c1837 2.9e-109 402.1 Caulobacterales Bacteria 1MVTF@1224,2KG3H@204458,2TQZE@28211,COG0739@1,COG0739@2 NA|NA|NA M peptidase MAG.T12.39_01657 450851.PHZ_c1836 1.4e-51 209.1 Caulobacterales bcp 1.11.1.15,2.7.7.42,2.7.7.89 ko:K00982,ko:K03564 ko00000,ko01000 Bacteria 1RD4R@1224,2KGSV@204458,2U6Z9@28211,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T12.39_01658 59538.XP_005972051.1 2.8e-163 581.6 Cetartiodactyla Mammalia 38DXN@33154,3BB3U@33208,3CR76@33213,3JDYW@40674,483UT@7711,48VAR@7742,4IY00@91561,COG0162@1,KOG2623@2759 NA|NA|NA J tyrosine--tRNA ligase MAG.T12.39_01659 450851.PHZ_c1834 5.5e-110 404.4 Caulobacterales anmK 2.7.1.170 ko:K09001 ko00000,ko01000 Bacteria 1MV4E@1224,2KFIB@204458,2TS4G@28211,COG2377@1,COG2377@2 NA|NA|NA F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling MAG.T12.39_01660 450851.PHZ_c1723 3e-108 397.9 Caulobacterales MA20_30730 ko:K07018 ko00000 Bacteria 1MUDY@1224,2KFQZ@204458,2TRMI@28211,COG2945@1,COG2945@2 NA|NA|NA S Alpha beta hydrolase MAG.T12.39_01661 450851.PHZ_c1722 3.9e-51 207.6 Caulobacterales iscR GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.8.1.7 ko:K04487,ko:K13643 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03000,ko03016,ko03029 Bacteria 1RDA4@1224,2KGVJ@204458,2U5B9@28211,COG1959@1,COG1959@2 NA|NA|NA K Rrf2 family MAG.T12.39_01662 366602.Caul_2587 1.7e-101 376.3 Caulobacterales nifS GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1MU1C@1224,2KFCA@204458,2TSQE@28211,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase, class V MAG.T12.39_01663 450851.PHZ_c1720 2.3e-252 877.9 Caulobacterales sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 ko:K07033,ko:K09014 ko00000 iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 Bacteria 1MVKY@1224,2KF2C@204458,2TRU6@28211,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufB MAG.T12.39_01665 450851.PHZ_c1719 3.2e-114 417.9 Caulobacterales sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1MUGK@1224,2KFZD@204458,2TS8T@28211,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC MAG.T12.39_01666 450851.PHZ_c1718 5e-85 321.2 Caulobacterales sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 1MVK0@1224,2KG18@204458,2TTK9@28211,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) MAG.T12.39_01667 59538.XP_005973385.1 5.6e-156 557.4 Vertebrata Metazoa 38E7D@33154,3BC56@33208,3CWJG@33213,481PR@7711,492J8@7742,COG1104@1,KOG1549@2759 NA|NA|NA E Cysteine desulfurase MAG.T12.39_01668 1449049.JONW01000013_gene4786 4.2e-48 197.2 Caulobacterales paaD ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1MZ9Y@1224,2KGNU@204458,2U72U@28211,COG2151@1,COG2151@2 NA|NA|NA S FeS assembly SUF system protein MAG.T12.39_01669 1382303.JPOM01000001_gene1391 3.3e-49 201.1 Caulobacterales iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 ko:K13628,ko:K15724,ko:K22063 ko00000,ko03016,ko03029 Bacteria 1RH6T@1224,2KGJ4@204458,2UBWJ@28211,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T12.39_01670 190650.CC_1851 6e-98 364.0 Caulobacterales MA20_16380 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 Bacteria 1MVQN@1224,2KG43@204458,2TUXD@28211,COG1024@1,COG1024@2 NA|NA|NA I PFAM Enoyl-CoA hydratase isomerase MAG.T12.39_01671 1292034.OR37_00234 6.8e-94 350.9 Caulobacterales 2.7.7.65 ko:K13590 ko04112,map04112 ko00000,ko00001,ko01000 Bacteria 1NC00@1224,2KFHZ@204458,2TU9T@28211,COG2199@1,COG3706@2 NA|NA|NA T Diguanylate cyclase MAG.T12.39_01672 450851.PHZ_c1711 6.6e-178 630.6 Caulobacterales rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MU49@1224,2KG79@204458,2TR6Q@28211,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T12.39_01673 450851.PHZ_c1569 0.0 1111.7 Caulobacterales parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1MVH1@1224,2KF3A@204458,2TQZV@28211,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule MAG.T12.39_01674 1292034.OR37_00113 2.6e-261 907.5 Caulobacterales glnA GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016853,GO:0016866,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0034022,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050486,GO:0050896,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.4.4.3,6.3.1.2 ko:K01915,ko:K20712 ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253,R06988,R09284 RC00010,RC01754,RC02798 ko00000,ko00001,ko01000,ko04147 iJN746.PP_5046 Bacteria 1MUGQ@1224,2KFXF@204458,2TSCR@28211,COG0174@1,COG0174@2 NA|NA|NA E highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues MAG.T12.39_01675 59538.XP_005973389.1 1.8e-48 198.4 Metazoa Metazoa 2RUKA@2759,3APS3@33154,3C2Y2@33208,COG0347@1 NA|NA|NA K Nitrogen regulatory protein P-II MAG.T12.39_01676 450851.PHZ_c1574 2.2e-205 721.8 Caulobacterales 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MVPC@1224,2KF3X@204458,2VEVD@28211,COG0183@1,COG0183@2 NA|NA|NA I acetyl-coa acetyltransferase MAG.T12.39_01677 450851.PHZ_c1575 3.1e-64 251.5 Caulobacterales yrgI 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1MYD7@1224,2KGUQ@204458,2TVST@28211,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family MAG.T12.39_01678 450851.PHZ_c1576 3.3e-163 581.6 Caulobacterales nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1MU1Q@1224,2KFFE@204458,2TT58@28211,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T12.39_01680 266264.Rmet_2148 3.4e-28 132.5 Burkholderiaceae ko:K14057 ko00000,ko03000 Bacteria 1K7DU@119060,1R785@1224,2VR27@28216,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain MAG.T12.39_01681 375286.mma_2430 9.5e-230 802.7 Oxalobacteraceae aslA 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MUJH@1224,2VNDQ@28216,4780B@75682,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T12.39_01682 1449049.JONW01000006_gene2883 1.2e-22 114.0 Proteobacteria ko:K03453 ko00000 2.A.28 Bacteria 1N9IH@1224,COG0385@1,COG0385@2 NA|NA|NA S Bile acid MAG.T12.39_01683 745310.G432_12925 9.3e-25 120.6 Sphingomonadales Bacteria 1Q0YA@1224,2CA7I@1,2KA4P@204457,2V5W7@28211,30E5G@2 NA|NA|NA MAG.T12.39_01684 1300345.LF41_3090 1.3e-20 105.9 Xanthomonadales Bacteria 1RM43@1224,1TFHB@1236,1X94Y@135614,COG4828@1,COG4828@2 NA|NA|NA S Protein of unknown function (DUF1622) MAG.T12.39_01685 1134912.AJTV01000015_gene382 3e-14 85.1 Alphaproteobacteria ko:K00389 ko00000 Bacteria 1RKB3@1224,2UEIP@28211,COG2149@1,COG2149@2 NA|NA|NA S Domain of unknown function (DUF202) MAG.T12.39_01686 1336243.JAEA01000001_gene1977 2.6e-124 451.8 Methylobacteriaceae Bacteria 1JRMU@119045,1MZ25@1224,2TRJH@28211,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 MAG.T12.39_01687 13690.CP98_03996 1.4e-125 456.4 Bacteria ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria COG3746@1,COG3746@2 NA|NA|NA MAG.T12.39_01688 450851.PHZ_c1700 1.6e-183 649.0 Caulobacterales tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 ko:K03545 ko00000 Bacteria 1MUJP@1224,2KFJJ@204458,2TS8W@28211,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase MAG.T12.39_01689 366602.Caul_2848 1.3e-89 335.9 Caulobacterales clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1MV46@1224,2KFYR@204458,2TR5M@28211,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T12.39_01690 1292034.OR37_00121 1.7e-62 246.1 Caulobacterales cicA 2.3.1.51,3.1.3.27,3.1.3.3 ko:K00655,ko:K01079,ko:K18697 ko00260,ko00561,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00561,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020,M00089 R00582,R02029,R02241,R09381 RC00004,RC00017,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004,ko01009 Bacteria 1MXGP@1224,2KGC8@204458,2U7SG@28211,COG0560@1,COG0560@2 NA|NA|NA E TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 MAG.T12.39_01693 450851.PHZ_c1814 2.2e-113 415.2 Caulobacterales clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1MVQK@1224,2KF7Z@204458,2TS3R@28211,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP MAG.T12.39_01694 247633.GP2143_16186 3.4e-29 135.6 Gammaproteobacteria ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1MWDK@1224,1RZ89@1236,COG0834@1,COG0834@2 NA|NA|NA ET belongs to the bacterial solute-binding protein 3 family MAG.T12.39_01695 1384056.N787_00550 9e-15 87.4 Xanthomonadales Bacteria 1NQ6H@1224,1TAA9@1236,1X8NS@135614,2DKZK@1,310GY@2 NA|NA|NA S Protein of unknown function (DUF3011) MAG.T12.39_01696 450851.PHZ_c1812 0.0 1248.8 Caulobacterales lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUV2@1224,2KFS4@204458,2TR4E@28211,COG0466@1,COG0466@2 NA|NA|NA O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner MAG.T12.39_01698 450851.PHZ_c1808 1.1e-87 330.1 Alphaproteobacteria Bacteria 1PDY4@1224,2U9ZA@28211,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T12.39_01699 1280949.HAD_02670 8.9e-173 613.2 Alphaproteobacteria Bacteria 1MV8Q@1224,2TRWW@28211,COG2124@1,COG2124@2 NA|NA|NA Q cytochrome P-450 MAG.T12.39_01700 450851.PHZ_c1807 4.9e-271 940.3 Caulobacterales 1.14.13.84 ko:K14520 ko00363,ko01100,ko01120,map00363,map01100,map01120 R06892 RC01644 ko00000,ko00001,ko01000 Bacteria 1MUQH@1224,2KIUB@204458,2TRG4@28211,COG2072@1,COG2072@2 NA|NA|NA C Flavin-binding monooxygenase-like MAG.T12.39_01701 435908.IDSA_07515 9.1e-61 240.0 Gammaproteobacteria Bacteria 1MXQ8@1224,1S5GX@1236,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase MAG.T12.39_01703 1449049.JONW01000007_gene4175 1.2e-56 225.7 Caulobacterales nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1RGUT@1224,2KGFI@204458,2U72Q@28211,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01704 450851.PHZ_c1804 1.7e-99 368.6 Caulobacterales nuoB GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 ko:K00331,ko:K03940 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 1MUI2@1224,2KFZS@204458,2TQK3@28211,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01705 450851.PHZ_c1803 8.9e-78 296.6 Caulobacterales nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MX4B@1224,2KGAJ@204458,2TSMT@28211,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01706 366602.Caul_2833 8.5e-205 719.5 Caulobacterales nuoD GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MVIN@1224,2KF7I@204458,2TQZ0@28211,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01707 450851.PHZ_c1801 7.5e-29 133.3 Caulobacterales ko:K07023 ko00000 Bacteria 1N60B@1224,2KHFQ@204458,2UEVR@28211,COG4538@1,COG4538@2 NA|NA|NA S SnoaL-like domain MAG.T12.39_01708 1229204.AMYY01000001_gene2839 5.9e-86 323.9 unclassified Alphaproteobacteria nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 ko:K00334,ko:K00335,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 1MWS2@1224,2TSEJ@28211,4BQ6K@82117,COG1905@1,COG1905@2 NA|NA|NA C TIGRFAM NADH-quinone oxidoreductase, E subunit MAG.T12.39_01709 59538.XP_005968363.1 4.5e-220 770.4 Cetartiodactyla Mammalia 38DDI@33154,3BA1E@33208,3CXVA@33213,3J83S@40674,483QH@7711,496VQ@7742,4J2F1@91561,COG1894@1,KOG2658@2759 NA|NA|NA C NADH dehydrogenase (ubiquinone) flavoprotein 1 MAG.T12.39_01710 69395.JQLZ01000005_gene3748 1.2e-304 1052.0 Caulobacterales nuoG 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1P8MN@1224,2KFE8@204458,2TS97@28211,COG1034@1,COG1034@2 NA|NA|NA C NADH-quinone oxidoreductase MAG.T12.39_01711 59538.XP_005968361.1 1.2e-157 562.8 Mammalia ND1 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204 1.6.5.3 ko:K03878 ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012 M00142 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko03029 3.D.1.6 Mammalia 39SC3@33154,3BGSE@33208,3D3H4@33213,3JDU5@40674,48BEV@7711,499PZ@7742,COG1005@1,KOG4770@2759 NA|NA|NA C NADH dehydrogenase (ubiquinone) activity MAG.T12.39_01713 366602.Caul_2824 4.4e-59 234.2 Caulobacterales nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 ko:K00338,ko:K03941 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 1MV90@1224,2KFX6@204458,2TRFE@28211,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01714 450851.PHZ_c1795 7.7e-77 293.5 Caulobacterales nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MWJV@1224,2KGD7@204458,2TRB2@28211,COG0839@1,COG0839@2 NA|NA|NA C Belongs to the complex I subunit 6 family MAG.T12.39_01715 1449049.JONW01000007_gene4189 3.1e-39 167.5 Caulobacterales nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1RH0S@1224,2KGNR@204458,2U93P@28211,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01716 59538.XP_005968358.1 1.8e-284 984.9 Cetartiodactyla ND5 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009636,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010257,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0046677,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0070482,GO:0071704,GO:0071840,GO:0072521,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:1901135,GO:1901360,GO:1901564,GO:1901698,GO:1901700,GO:1902494,GO:1990204 1.6.5.3 ko:K03883 ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012 M00142 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko03029 3.D.1.6 Mammalia 38F5W@33154,3BEVW@33208,3CTS4@33213,3JBRY@40674,48A2B@7711,48WJ8@7742,4J1M8@91561,COG1007@1,KOG4668@2759 NA|NA|NA C Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone MAG.T12.39_01717 190650.CC_1938 1.5e-219 768.8 Caulobacterales nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MV7V@1224,2KFV4@204458,2TSNK@28211,COG1008@1,COG1008@2 NA|NA|NA C NADH ubiquinone oxidoreductase MAG.T12.39_01718 450851.PHZ_c1791 6.4e-167 594.0 Caulobacterales nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MV56@1224,2KG7D@204458,2TQMX@28211,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient MAG.T12.39_01719 450851.PHZ_c1790 4.7e-73 281.2 Caulobacterales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03523,ko:K03524 ko00770,ko00780,ko01100,ko02010,map00770,map00780,map01100,map02010 M00120,M00581,M00582 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 2.A.88.1,2.A.88.2 iLJ478.TM0224 Bacteria 1MWCC@1224,2KFF4@204458,2TS82@28211,COG0340@1,COG0340@2 NA|NA|NA H biotin lipoate A B protein ligase MAG.T12.39_01720 450851.PHZ_c1789 4.9e-113 414.1 Caulobacterales coaX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1986 Bacteria 1MUYA@1224,2KFJA@204458,2TS5A@28211,COG1521@1,COG1521@2 NA|NA|NA F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis MAG.T12.39_01721 450851.PHZ_c1788 4e-245 854.0 Caulobacterales rnj GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MUGV@1224,2KFKR@204458,2TQTR@28211,COG0595@1,COG0595@2 NA|NA|NA S beta-lactamase MAG.T12.39_01722 326424.FRAAL3522 3.5e-143 515.8 Actinobacteria Bacteria 2IHED@201174,COG1804@1,COG1804@2 NA|NA|NA C CoA-transferase family III MAG.T12.39_01723 450851.PHZ_c1787 6.2e-62 243.4 Caulobacterales mce 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 Bacteria 1RCYU@1224,2KGKT@204458,2U728@28211,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T12.39_01724 69395.JQLZ01000005_gene3761 2.1e-20 104.8 Caulobacterales MA20_37275 Bacteria 1PQAF@1224,2KH83@204458,2V2Q0@28211,COG5454@1,COG5454@2 NA|NA|NA S Protein of unknown function (DUF1467) MAG.T12.39_01725 450851.PHZ_c1784 1.9e-154 552.4 Caulobacterales lolC ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 1MVV7@1224,2KFSM@204458,2TRBX@28211,COG4591@1,COG4591@2 NA|NA|NA M lipoprotein releasing system, transmembrane protein, LolC E family MAG.T12.39_01726 450851.PHZ_c1783 5.3e-79 300.8 Caulobacterales lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043167,GO:0043168,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351,GO:1990778 ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 1MVSQ@1224,2KF1X@204458,2TSBE@28211,COG1136@1,COG1136@2 NA|NA|NA P Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner MAG.T12.39_01728 450851.PHZ_c1782 0.0 1723.4 Caulobacterales dnaE GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MUIF@1224,2KFFJ@204458,2TSCN@28211,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase MAG.T12.39_01729 190650.CC_1923 2.9e-113 414.8 Caulobacterales rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MU33@1224,2KFB2@204458,2TRXE@28211,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family MAG.T12.39_01730 59538.XP_005968352.1 5.1e-133 480.7 Bilateria Metazoa 39Q3J@33154,3CQZ6@33208,3E74H@33213,COG0264@1,KOG1071@2759 NA|NA|NA J Elongation factor Ts 1, mitochondrial-like MAG.T12.39_01731 450851.PHZ_c1778 1.3e-104 386.0 Caulobacterales pyrH GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0033862,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 Bacteria 1MV3N@1224,2KFEK@204458,2TQYN@28211,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP MAG.T12.39_01732 59538.XP_005968350.1 1.3e-67 262.7 Eukaryota RRF1 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006996,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032543,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0070126,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 ko:K02838,ko:K03283 ko03040,ko04010,ko04141,ko04144,ko04213,ko04612,ko04915,ko05134,ko05145,ko05162,ko05164,ko05169,map03040,map04010,map04141,map04144,map04213,map04612,map04915,map05134,map05145,map05162,map05164,map05169 M00353,M00355 ko00000,ko00001,ko00002,ko01009,ko03009,ko03012,ko03029,ko03041,ko03051,ko03110,ko04131,ko04147,ko04516 1.A.33.1 Eukaryota COG0233@1,KOG4759@2759 NA|NA|NA J ribosomal large subunit binding MAG.T12.39_01733 450851.PHZ_c1776 4.9e-100 370.9 Caulobacterales uppS GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880 Bacteria 1MVP1@1224,2KFIA@204458,2TTVJ@28211,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T12.39_01734 450851.PHZ_c1775 8e-93 347.1 Caulobacterales cdsA 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWSV@1224,2KJX8@204458,2U9ED@28211,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family MAG.T12.39_01735 1292034.OR37_00166 3e-130 471.9 Caulobacterales dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 1MU4G@1224,2KFI8@204458,2TSD1@28211,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) MAG.T12.39_01736 450851.PHZ_c1773 1.3e-128 466.5 Caulobacterales rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 ko:K04771,ko:K11749 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU91@1224,2KG52@204458,2TQXJ@28211,COG0750@1,COG0750@2 NA|NA|NA M TIGRFAM membrane-associated zinc metalloprotease MAG.T12.39_01737 450851.PHZ_c1772 0.0 1137.9 Caulobacterales bamA ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 1MU0D@1224,2KEXW@204458,2TR7W@28211,COG4775@1,COG4775@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T12.39_01738 450851.PHZ_c1771 4.2e-46 191.4 Caulobacterales ompH ko:K06142 ko00000 Bacteria 1N3FR@1224,2KH1Z@204458,2UDBZ@28211,COG2825@1,COG2825@2 NA|NA|NA M Outer membrane protein (OmpH-like) MAG.T12.39_01739 450851.PHZ_c1770 1.3e-76 293.5 Caulobacterales lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MUX6@1224,2KFNW@204458,2TS8U@28211,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T12.39_01740 450851.PHZ_c1769 8.7e-57 226.5 Caulobacterales fabZ GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1RH2T@1224,2KGJJ@204458,2U7G4@28211,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs MAG.T12.39_01741 69395.JQLZ01000005_gene3782 1.5e-61 243.0 Caulobacterales lpxA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 iIT341.HP1375,iPC815.YPO1056 Bacteria 1MUHQ@1224,2KFFI@204458,2TRK9@28211,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T12.39_01742 450851.PHZ_c1767 7.4e-99 367.1 Caulobacterales cdsA2 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748,ko:K09949 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 Bacteria 1MWTH@1224,2KFXI@204458,2U4AB@28211,COG3494@1,COG3494@2 NA|NA|NA S Protein of unknown function (DUF1009) MAG.T12.39_01743 450851.PHZ_c1766 6.6e-122 444.1 Caulobacterales lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478,iIT341.HP0867 Bacteria 1MVBI@1224,2KFQ6@204458,2TSEA@28211,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T12.39_01744 450851.PHZ_c1765 6.2e-230 803.1 Caulobacterales gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 iIT341.HP0026 Bacteria 1MUKX@1224,2KFUK@204458,2TS63@28211,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family MAG.T12.39_01745 450851.PHZ_c1764 2.8e-204 718.0 Caulobacterales gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iEC042_1314.EC042_2616,iIT341.HP0476 Bacteria 1MUCR@1224,2KFES@204458,2TRSU@28211,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) MAG.T12.39_01746 450851.PHZ_c1763 3.9e-200 704.9 Caulobacterales comA ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1MUKF@1224,2KF82@204458,2TRD5@28211,COG0658@1,COG0658@2 NA|NA|NA S ComEC Rec2-related protein MAG.T12.39_01747 450851.PHZ_c1762 3.1e-106 391.3 Caulobacterales lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1MW80@1224,2KF4D@204458,2TT7W@28211,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair MAG.T12.39_01748 1449049.JONW01000007_gene4237 2.1e-103 382.1 Caulobacterales trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2494 Bacteria 1MW5K@1224,2KFCQ@204458,2TSZE@28211,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family MAG.T12.39_01749 450851.PHZ_c1760 1e-126 459.9 Caulobacterales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPV@1224,2KFBY@204458,2TR8S@28211,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) MAG.T12.39_01750 69395.JQLZ01000005_gene3911 2.7e-84 318.2 Caulobacterales trpG 2.4.2.18,4.1.3.27 ko:K01658,ko:K13497 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV5Y@1224,2KF9T@204458,2TU3N@28211,COG0512@1,COG0512@2 NA|NA|NA EH Anthranilate synthase MAG.T12.39_01752 1248916.ANFY01000017_gene1379 2.7e-70 272.3 Sphingomonadales ydiY ko:K07283 ko00000 Bacteria 1MWI4@1224,2KCGR@204457,2UBFT@28211,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function, DUF481 MAG.T12.39_01753 450851.PHZ_c1757 1.1e-238 832.4 Caulobacterales trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVBJ@1224,2KFAR@204458,2TRWB@28211,COG0147@1,COG0147@2 NA|NA|NA E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia MAG.T12.39_01754 450851.PHZ_c1756 1.6e-168 599.7 Caulobacterales 5.2.1.8 ko:K01802,ko:K03770,ko:K03771 ko00000,ko01000,ko03110 Bacteria 1MWV0@1224,2KF7G@204458,2TRYU@28211,COG0760@1,COG0760@2 NA|NA|NA O SurA N-terminal domain MAG.T12.39_01755 450851.PHZ_c1755 8.5e-91 340.1 Caulobacterales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MWK5@1224,2KFU7@204458,2TS6I@28211,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) MAG.T12.39_01756 649638.Trad_1633 4.9e-202 710.7 Deinococcus-Thermus icd 1.1.1.41,1.1.1.42 ko:K00030,ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R00709,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1WIRG@1297,COG0473@1,COG0473@2 NA|NA|NA C Isocitrate isopropylmalate dehydrogenase MAG.T12.39_01757 1449049.JONW01000006_gene2698 5.4e-41 174.5 Caulobacterales ygfJ 2.7.7.76 ko:K07141,ko:K07402 ko00790,map00790 R11582 ko00000,ko00001,ko01000 Bacteria 1MW0X@1224,2KHJ5@204458,2TR5D@28211,COG2068@1,COG2068@2 NA|NA|NA S Molybdopterin MAG.T12.39_01758 450851.PHZ_c0280 6e-143 513.8 Caulobacterales moaA 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394 RC03420 ko00000,ko00001,ko01000 Bacteria 1MW3W@1224,2KFTM@204458,2TQQP@28211,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate MAG.T12.39_01759 1292034.OR37_01666 3.1e-18 97.4 Caulobacterales moaD 2.7.7.77,2.8.1.12,4.6.1.17 ko:K03636,ko:K03637,ko:K03752,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395,R11372,R11581 RC02507,RC03425 ko00000,ko00001,ko01000 Bacteria 1NC2A@1224,2KHCE@204458,2UG29@28211,COG1977@1,COG1977@2 NA|NA|NA H TIGRFAM molybdopterin converting factor, subunit 1 MAG.T12.39_01760 1292034.OR37_01665 2.9e-54 218.0 Caulobacterales moaE 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 1RGUX@1224,2KGU8@204458,2U73K@28211,COG0314@1,COG0314@2 NA|NA|NA H Molybdopterin MAG.T12.39_01761 450851.PHZ_c0277 9.7e-79 299.7 Caulobacterales moaB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 R09726 RC00002 ko00000,ko00001,ko01000 Bacteria 1R9W2@1224,2KG9Q@204458,2TTA8@28211,COG0521@1,COG0521@2 NA|NA|NA H May be involved in the biosynthesis of molybdopterin MAG.T12.39_01762 450851.PHZ_c0276 4.9e-60 237.3 Caulobacterales moaC GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 1RCYZ@1224,2KGJZ@204458,2U747@28211,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) MAG.T12.39_01763 450851.PHZ_c0275 5.3e-135 487.6 Caulobacterales 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 1MVD5@1224,2KFZN@204458,2TQRI@28211,COG0303@1,COG0303@2 NA|NA|NA H TIGRFAM molybdenum cofactor synthesis domain MAG.T12.39_01764 1346791.M529_21730 3.6e-35 154.8 Sphingomonadales Bacteria 1QU5E@1224,2K6A0@204457,2TW0B@28211,COG2771@1,COG2771@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T12.39_01765 1292034.OR37_01910 1.1e-52 213.4 Caulobacterales Bacteria 1RF4V@1224,2KIU7@204458,2U6ZE@28211,COG3658@1,COG3658@2 NA|NA|NA C Prokaryotic cytochrome b561 MAG.T12.39_01766 1449049.JONW01000006_gene2705 1.3e-102 379.8 Caulobacterales ko:K07402 ko00000 Bacteria 1MXKU@1224,2KF94@204458,2TUF3@28211,COG1975@1,COG1975@2 NA|NA|NA O XdhC and CoxI family MAG.T12.39_01767 450851.PHZ_c0273 5.7e-105 387.5 Caulobacterales ko:K07257 ko00000 Bacteria 1RC4U@1224,2KGCP@204458,2U6NK@28211,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase MAG.T12.39_01768 509190.Cseg_4059 2.5e-150 538.5 Caulobacterales ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 1QTX1@1224,2KFIP@204458,2TQQC@28211,COG0686@1,COG0686@2 NA|NA|NA C Belongs to the AlaDH PNT family MAG.T12.39_01769 509190.Cseg_3830 7.6e-83 313.5 Caulobacterales mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129,3.4.16.4 ko:K03814,ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1RDAQ@1224,2KG9J@204458,2U0NP@28211,COG0744@1,COG0744@2 NA|NA|NA M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors MAG.T12.39_01770 450851.PHZ_c0268 1.2e-104 386.0 Caulobacterales Bacteria 1PG8V@1224,2KHYX@204458,2U59W@28211,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family MAG.T12.39_01771 450851.PHZ_c0269 1.2e-124 453.0 Caulobacterales MA20_06560 Bacteria 1MV7S@1224,2KK7E@204458,2TTNW@28211,COG2319@1,COG2319@2 NA|NA|NA S WD40 repeats MAG.T12.39_01772 450851.PHZ_c0270 5.9e-52 210.3 Caulobacterales exbD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0023052,GO:0031224,GO:0031226,GO:0031647,GO:0031992,GO:0032991,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0065008,GO:0071944,GO:0098796,GO:0098797 ko:K03559,ko:K03560 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 iPC815.YPO0683 Bacteria 1RJEF@1224,2KGS4@204458,2U9AW@28211,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein, ExbD MAG.T12.39_01773 450851.PHZ_c3369 3.5e-154 551.2 Caulobacterales cobW Bacteria 1MVZV@1224,2KFAH@204458,2TS4B@28211,COG0523@1,COG0523@2 NA|NA|NA S Cobalamin synthesis protein MAG.T12.39_01774 450851.PHZ_c3368 2.3e-50 206.1 Caulobacterales czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1MVQB@1224,2KGSQ@204458,2TSE3@28211,COG1230@1,COG1230@2 NA|NA|NA P Cation efflux family MAG.T12.39_01775 450851.PHZ_c3367 6.2e-79 301.6 Caulobacterales 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1NMW4@1224,2KGVQ@204458,2TX7R@28211,COG2367@1,COG2367@2 NA|NA|NA V beta-lactamase MAG.T12.39_01776 1449049.JONW01000006_gene2926 6.7e-51 207.2 Caulobacterales rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZEW@1224,2KGHU@204458,2UBT3@28211,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 MAG.T12.39_01777 1282360.ABAC460_02490 7e-32 142.9 Caulobacterales rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZGH@1224,2KGZX@204458,2UBUX@28211,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family MAG.T12.39_01778 450851.PHZ_c0256 5.8e-41 174.1 Caulobacterales MA20_44020 Bacteria 1N6Q1@1224,2KGT3@204458,2UG72@28211,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T12.39_01779 1292034.OR37_00580 4.9e-153 547.4 Caulobacterales obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1MUGZ@1224,2KF3Z@204458,2TR5I@28211,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control MAG.T12.39_01780 450851.PHZ_c0253 1.2e-141 509.6 Caulobacterales proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_3198 Bacteria 1MUBG@1224,2KF6W@204458,2TRKB@28211,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate MAG.T12.39_01781 450851.PHZ_c0312 2.1e-179 635.2 Caulobacterales GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008410,GO:0015977,GO:0016740,GO:0016782,GO:0043427,GO:0071704 2.8.3.16,2.8.3.20 ko:K07749,ko:K18313 R10640,R10641 RC00014 ko00000,ko01000 Bacteria 1MU2K@1224,2KFXD@204458,2TR7Q@28211,COG1804@1,COG1804@2 NA|NA|NA C CoA-transferase family III MAG.T12.39_01782 450851.PHZ_c0313 1.2e-92 346.3 Caulobacterales nagK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0008948,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0018773,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 3.7.1.20 ko:K16165 ko00350,ko01100,ko01120,map00350,map01100,map01120 R01085 RC00326,RC00446 ko00000,ko00001,ko01000 Bacteria 1MVFA@1224,2KGG6@204458,2TRTM@28211,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family MAG.T12.39_01783 450851.PHZ_c0314 1.2e-72 279.6 Caulobacterales maiA 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 Bacteria 1RA4Y@1224,2KG8Y@204458,2U5B6@28211,COG0625@1,COG0625@2 NA|NA|NA O maleylacetoacetate isomerase MAG.T12.39_01784 450851.PHZ_c0315 1.2e-88 332.8 Caulobacterales can 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273 Bacteria 1NGFN@1224,2KG20@204458,2TRPD@28211,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T12.39_01785 366602.Caul_0182 1.3e-123 449.5 Caulobacterales Bacteria 1MUNT@1224,2KFIE@204458,2TU3Y@28211,COG3491@1,COG3491@2 NA|NA|NA C Belongs to the iron ascorbate-dependent oxidoreductase family MAG.T12.39_01786 509190.Cseg_3946 3.6e-102 377.9 Caulobacterales scoA 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 1MVEI@1224,2KF55@204458,2TTE6@28211,COG1788@1,COG1788@2 NA|NA|NA I TIGRFAM 3-oxoacid CoA-transferase, A subunit MAG.T12.39_01787 366602.Caul_4700 4.5e-96 357.5 Caulobacterales scoB 2.8.3.5 ko:K01027,ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 1RA4V@1224,2KFWH@204458,2TQS5@28211,COG2057@1,COG2057@2 NA|NA|NA I TIGRFAM 3-oxoacid CoA-transferase, B subunit MAG.T12.39_01788 450851.PHZ_c0321 7.4e-53 213.8 Caulobacterales msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1NC84@1224,2KGVE@204458,2TTDD@28211,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T12.39_01789 69395.JQLZ01000004_gene800 0.0 1384.8 Caulobacterales Bacteria 1PSM0@1224,2KHTG@204458,2U3MX@28211,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T12.39_01790 450851.PHZ_c0324 3.7e-129 468.0 Caulobacterales 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 R01416 RC00177 ko00000,ko00001,ko01000 Bacteria 1MX65@1224,2KF87@204458,2U0RR@28211,COG2957@1,COG2957@2 NA|NA|NA E Belongs to the agmatine deiminase family MAG.T12.39_01791 450851.PHZ_c0325 1.1e-148 532.7 Caulobacterales aguB 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 R01152 RC00096 ko00000,ko00001,ko01000 Bacteria 1MXG5@1224,2KF05@204458,2TVCS@28211,COG0388@1,COG0388@2 NA|NA|NA S N-carbamoylputrescine amidase MAG.T12.39_01792 190650.CC_0213 1.4e-42 179.5 Alphaproteobacteria Bacteria 1RCX2@1224,2U97G@28211,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T12.39_01793 450851.PHZ_c0327 4.1e-124 451.1 Caulobacterales MA20_35600 Bacteria 1MUR2@1224,2KHN2@204458,2TUM7@28211,COG2030@1,COG2030@2 NA|NA|NA I N-terminal half of MaoC dehydratase MAG.T12.39_01794 450851.PHZ_c0328 2.4e-107 395.2 Caulobacterales Bacteria 1Q227@1224,2KFMI@204458,2U2IQ@28211,COG1262@1,COG1262@2 NA|NA|NA S SapC MAG.T12.39_01795 1449049.JONW01000005_gene1663 2e-54 218.4 Caulobacterales 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 Bacteria 1RHKJ@1224,2KGQ1@204458,2U999@28211,COG2030@1,COG2030@2 NA|NA|NA I dehydratase MAG.T12.39_01796 509190.Cseg_3935 2.2e-211 742.3 Caulobacterales dsbD 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 1MU8W@1224,2KF2F@204458,2TTUM@28211,COG4232@1,COG4232@2,COG4233@1,COG4233@2 NA|NA|NA CO cytochrome c biogenesis protein MAG.T12.39_01797 450851.PHZ_c0331 3.6e-171 608.2 Caulobacterales pgi GO:0001701,GO:0001704,GO:0001707,GO:0002262,GO:0002376,GO:0002637,GO:0002639,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007369,GO:0007498,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009410,GO:0009435,GO:0009438,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010466,GO:0010594,GO:0010595,GO:0010605,GO:0010632,GO:0010634,GO:0010941,GO:0010951,GO:0014070,GO:0014072,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0016866,GO:0017144,GO:0018130,GO:0019222,GO:0019242,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030246,GO:0030334,GO:0030335,GO:0031090,GO:0031253,GO:0031323,GO:0031324,GO:0031625,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0032880,GO:0033500,GO:0034101,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0040012,GO:0040017,GO:0042180,GO:0042181,GO:0042221,GO:0042493,GO:0042592,GO:0042593,GO:0042866,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043278,GO:0043279,GO:0043281,GO:0043436,GO:0043523,GO:0043524,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045861,GO:0046031,GO:0046034,GO:0046184,GO:0046185,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048029,GO:0048332,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048598,GO:0048646,GO:0048729,GO:0048856,GO:0048872,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051023,GO:0051024,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051156,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060170,GO:0060255,GO:0060359,GO:0060548,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0071704,GO:0071944,GO:0072330,GO:0072347,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097458,GO:0098588,GO:0098590,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901214,GO:1901215,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1903530,GO:1903532,GO:1904951,GO:2000116,GO:2000117,GO:2000145,GO:2000147 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUFP@1224,2KFKJ@204458,2TQKP@28211,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family MAG.T12.39_01798 1366050.N234_07345 2e-187 662.1 Burkholderiaceae ko:K00666 ko00000,ko01000,ko01004 Bacteria 1K4JS@119060,1MUIC@1224,2VI72@28216,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_01799 402881.Plav_2714 4.2e-97 361.3 Alphaproteobacteria Bacteria 1MVYG@1224,2TSTP@28211,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T12.39_01800 450851.PHZ_c0332 5.6e-206 723.8 Caulobacterales hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV2K@1224,2KFHM@204458,2TSTH@28211,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase MAG.T12.39_01801 450851.PHZ_c0333 1.1e-89 337.0 Caulobacterales hisZ ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 Bacteria 1MWIG@1224,2KF5X@204458,2TTQ4@28211,COG3705@1,COG3705@2 NA|NA|NA E Histidyl-tRNA synthetase MAG.T12.39_01802 450851.PHZ_c0334 8.1e-110 403.7 Caulobacterales hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUCY@1224,2KFUA@204458,2TT0H@28211,COG0040@1,COG0040@2 NA|NA|NA F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity MAG.T12.39_01804 1122132.AQYH01000008_gene2491 1.7e-125 456.1 Rhizobiaceae ko:K07007 ko00000 Bacteria 1MUGC@1224,2TR1K@28211,4B85K@82115,COG2081@1,COG2081@2 NA|NA|NA S HI0933-like protein MAG.T12.39_01805 59538.XP_005961488.1 8e-216 756.9 Cetartiodactyla Mammalia 38BNF@33154,3B9I2@33208,3CW8Q@33213,3JBKD@40674,481YV@7711,49434@7742,4IY13@91561,COG3590@1,KOG3624@2759 NA|NA|NA E Endothelin-converting enzyme MAG.T12.39_01806 1449049.JONW01000005_gene1641 7.4e-181 640.6 Caulobacterales kefB ko:K03455 ko00000 2.A.37 Bacteria 1MV34@1224,2KG6X@204458,2TRC5@28211,COG0475@1,COG0475@2,COG1226@1,COG1226@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T12.39_01807 450851.PHZ_c0337 4.7e-147 527.7 Caulobacterales Bacteria 1N6EM@1224,2KFB3@204458,2U17R@28211,COG2885@1,COG2885@2,COG3637@1,COG3637@2 NA|NA|NA M Belongs to the ompA family MAG.T12.39_01808 450851.PHZ_c0341 0.0 1116.7 Caulobacterales nrdA 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1MUJ8@1224,2KFII@204458,2TS19@28211,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides MAG.T12.39_01809 450851.PHZ_c0344 2.3e-179 634.8 Caulobacterales nrdB 1.17.4.1 ko:K00526,ko:K03676 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03110,ko03400 Bacteria 1MWUS@1224,2KFA5@204458,2TS3X@28211,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides MAG.T12.39_01810 450851.PHZ_c0349 2.2e-106 392.1 Caulobacterales htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1MUV4@1224,2KG3X@204458,2TS3N@28211,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family MAG.T12.39_01811 450851.PHZ_c0352 6.4e-147 527.3 Caulobacterales gltP ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7 Bacteria 1MU0Q@1224,2KG1F@204458,2TUFB@28211,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family MAG.T12.39_01812 450851.PHZ_c0353 4e-225 787.3 Caulobacterales amn GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008714,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464 3.2.2.4 ko:K01241 ko00230,map00230 R00182 RC00063,RC00318 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c22520,iECOK1_1307.ECOK1_2159,iECP_1309.ECP_1955,iETEC_1333.ETEC_2095,iNRG857_1313.NRG857_09950,iUMN146_1321.UM146_07225,ic_1306.c2444 Bacteria 1MUMQ@1224,2KF3S@204458,2TSX1@28211,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations MAG.T12.39_01813 1244869.H261_14485 1.7e-125 456.1 Rhodospirillales spt 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MWHJ@1224,2JRAI@204441,2TQSN@28211,COG0075@1,COG0075@2 NA|NA|NA E Aminotransferase class-V MAG.T12.39_01814 366602.Caul_0145 4e-79 301.6 Caulobacterales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1NRB4@1224,2KHT8@204458,2TU91@28211,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T12.39_01815 1382303.JPOM01000001_gene267 3.6e-58 231.1 Caulobacterales tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5 ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K11991 ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223 RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000,ko01002,ko01011,ko03016 Bacteria 1RGU0@1224,2KGJF@204458,2U77Q@28211,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) MAG.T12.39_01816 450851.PHZ_c3167 3e-117 428.7 Caulobacterales rluB 5.4.99.19,5.4.99.20,5.4.99.21,5.4.99.22 ko:K06178,ko:K06181,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1MUCE@1224,2KFBW@204458,2TQP2@28211,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T12.39_01817 1280944.HY17_04235 1.6e-55 223.0 Alphaproteobacteria 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 R03026 RC00831 ko00000,ko00001,ko01000 Bacteria 1RG4N@1224,2U8TJ@28211,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_01818 450851.PHZ_c3166 3.9e-75 287.7 Caulobacterales rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1MXKW@1224,2KGBU@204458,2U70Y@28211,COG0742@1,COG0742@2 NA|NA|NA L Methyltransferase MAG.T12.39_01819 190650.CC_3510 1.2e-113 416.4 Caulobacterales Bacteria 1PR6U@1224,2KGDZ@204458,2TUC6@28211,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family MAG.T12.39_01820 633149.Bresu_0679 7.1e-77 294.3 Caulobacterales sbtA ko:K07086 ko00000 Bacteria 1N85P@1224,2KGKU@204458,2TRK2@28211,COG3329@1,COG3329@2 NA|NA|NA S Na+-dependent bicarbonate transporter superfamily MAG.T12.39_01821 1120963.KB894508_gene3916 3.8e-29 135.6 Gammaproteobacteria Bacteria 1R3KZ@1224,1T69B@1236,2DM87@1,32549@2 NA|NA|NA MAG.T12.39_01822 450851.PHZ_c0777 1.1e-170 605.9 Caulobacterales ilvC 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iJN746.PP_4678,iLJ478.TM0550 Bacteria 1MV7M@1224,2KF0A@204458,2TRXI@28211,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate MAG.T12.39_01823 450851.PHZ_c0821 1.5e-21 110.2 Caulobacterales cigR Bacteria 1RJVB@1224,2KHA5@204458,2U9H6@28211,COG5455@1,COG5455@2 NA|NA|NA D Nickel/cobalt transporter regulator MAG.T12.39_01824 366602.Caul_3383 5.3e-61 240.7 Caulobacterales Bacteria 1RHYI@1224,2KH45@204458,2U7AN@28211,COG3803@1,COG3803@2 NA|NA|NA S Bacterial protein of unknown function (DUF924) MAG.T12.39_01825 1382303.JPOM01000001_gene2059 8.8e-124 449.9 Caulobacterales thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUBD@1224,2KFFT@204458,2TQSB@28211,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis MAG.T12.39_01826 1382303.JPOM01000001_gene1980 4.2e-68 264.2 Caulobacterales folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1RH0P@1224,2KGH5@204458,2U9GC@28211,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis MAG.T12.39_01827 450851.PHZ_c0815 1.8e-150 539.3 Caulobacterales 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MXVD@1224,2KFUI@204458,2TVCW@28211,COG3386@1,COG3386@2 NA|NA|NA G SMP-30/Gluconolaconase/LRE-like region MAG.T12.39_01828 1038866.KB902824_gene1213 5e-164 583.9 Bradyrhizobiaceae Bacteria 1MVIX@1224,2TT2F@28211,3JX03@41294,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family MAG.T12.39_01829 366602.Caul_5296 2.3e-197 694.9 Caulobacterales MA20_04500 Bacteria 1MV8Q@1224,2KHW8@204458,2TRWW@28211,COG2124@1,COG2124@2 NA|NA|NA C cytochrome P450 MAG.T12.39_01830 1121106.JQKB01000003_gene2491 5.9e-91 341.3 Rhodospirillales ko:K18372 ko00640,map00640 R10705 RC00460,RC00461 ko00000,ko00001,ko01000 Bacteria 1MVPR@1224,2JUZ6@204441,2TRWZ@28211,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T12.39_01831 450851.PHZ_c0810 1e-197 696.0 Caulobacterales Bacteria 1MVJC@1224,2KF8U@204458,2TVJ8@28211,COG1960@1,COG1960@2 NA|NA|NA C Acyl-CoA dehydrogenase, middle domain MAG.T12.39_01832 450851.PHZ_c0809 5e-31 140.2 Caulobacterales Bacteria 1N65K@1224,2KHAJ@204458,2UE49@28211,COG1359@1,COG1359@2 NA|NA|NA S PFAM Antibiotic biosynthesis monooxygenase MAG.T12.39_01834 398578.Daci_1652 4.7e-09 68.2 Comamonadaceae Bacteria 1MVXW@1224,2VRGU@28216,4AHQM@80864,COG3926@1,COG3926@2 NA|NA|NA S Predicted Peptidoglycan domain MAG.T12.39_01835 2074.JNYD01000015_gene4570 1e-33 151.0 Actinobacteria Bacteria 2DUKN@1,2GNCZ@201174,33R4Y@2 NA|NA|NA MAG.T12.39_01836 1217714.F975_01652 8.9e-10 72.0 Proteobacteria Bacteria 1R710@1224,28MV6@1,2ZB2T@2 NA|NA|NA MAG.T12.39_01837 1449049.JONW01000010_gene3642 2.4e-79 302.0 Caulobacterales hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 ko:K04082,ko:K05801 ko00000,ko03029,ko03110 Bacteria 1N270@1224,2KGEP@204458,2TTX1@28211,COG1076@1,COG1076@2 NA|NA|NA O Molecular chaperone DnaJ MAG.T12.39_01838 450851.PHZ_c0802 0.0 1585.1 Caulobacterales hyuB 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473,ko:K01474 ko00330,ko00480,ko01100,map00330,map00480,map01100 R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 iNJ661.Rv0266c Bacteria 1MU2Y@1224,2KFQR@204458,2TQZ6@28211,COG0145@1,COG0145@2,COG0146@1,COG0146@2 NA|NA|NA EQ Hydantoinase/oxoprolinase N-terminal region MAG.T12.39_01839 450851.PHZ_c0801 5.1e-37 161.4 Caulobacterales Bacteria 1NDX6@1224,2EJIP@1,2KH6H@204458,2UMN5@28211,33D9K@2 NA|NA|NA MAG.T12.39_01840 450851.PHZ_c1818 3.7e-82 311.2 Alphaproteobacteria VP2116 ko:K07396 ko00000 Bacteria 1RIN9@1224,2UBM6@28211,COG3531@1,COG3531@2 NA|NA|NA O DSBA-like thioredoxin domain MAG.T12.39_01841 402881.Plav_3012 1.9e-35 155.2 Alphaproteobacteria Bacteria 1N5IW@1224,2E1KM@1,2UDKY@28211,32WY3@2 NA|NA|NA S Methylmuconolactone methyl-isomerase MAG.T12.39_01842 450851.PHZ_c2680 0.0 1307.4 Caulobacterales pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 Bacteria 1MUCI@1224,2KFB1@204458,2TRUM@28211,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase N MAG.T12.39_01843 450851.PHZ_c2681 6.2e-111 407.9 Caulobacterales MA20_15195 2.7.13.3 ko:K07716 ko02020,ko04112,map02020,map04112 M00511 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1NRP8@1224,2KFU3@204458,2TRHH@28211,COG0642@1,COG2202@1,COG2202@2,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T12.39_01845 1458357.BG58_38110 9.3e-09 67.0 Burkholderiaceae Bacteria 1K7Y4@119060,1NG8N@1224,2EG2K@1,2VYZR@28216,339UJ@2 NA|NA|NA MAG.T12.39_01846 1035191.HMPREF0185_00136 1.8e-57 228.8 Caulobacterales sigW ko:K03088 ko00000,ko03021 Bacteria 1MX7T@1224,2KGEK@204458,2U5A1@28211,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T12.39_01848 450851.PHZ_c2686 0.0 1264.6 Caulobacterales glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 1MU4I@1224,2KG2V@204458,2TRY7@28211,COG1391@1,COG1391@2 NA|NA|NA H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell MAG.T12.39_01849 450851.PHZ_c2687 6.8e-169 600.5 Caulobacterales ragB Bacteria 1MW8M@1224,2KJVK@204458,2TUSJ@28211,COG0642@1,COG2205@2,COG2770@1,COG2770@2 NA|NA|NA T HAMP domain MAG.T12.39_01850 1121123.AUAO01000005_gene1807 7e-100 370.2 Caulobacterales Bacteria 1MU67@1224,2KF7M@204458,2TRTZ@28211,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_01851 450851.PHZ_c2689 2.3e-167 595.5 Caulobacterales dop GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2KF74@204458,2TQPZ@28211,COG0265@1,COG0265@2 NA|NA|NA O Belongs to the peptidase S1C family MAG.T12.39_01852 450851.PHZ_c2690 1.4e-36 159.5 Caulobacterales ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018 R05712 RC00176 ko00000,ko02000 9.B.14.1 Bacteria 1MZZ5@1224,2KGYD@204458,2U96P@28211,COG3088@1,COG3088@2 NA|NA|NA O subunit of a heme lyase MAG.T12.39_01853 450851.PHZ_c2691 7.4e-267 926.4 Caulobacterales ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 ko:K02198,ko:K04016 R05712 RC00176 ko00000,ko02000 9.B.14.1 Bacteria 1MUQS@1224,2KF11@204458,2TRNG@28211,COG1138@1,COG1138@2 NA|NA|NA O Cytochrome c-type biogenesis protein MAG.T12.39_01854 450851.PHZ_c2692 3.6e-58 231.1 Caulobacterales ccmE GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 ko:K02197 ko00000 iSSON_1240.SSON_2255 Bacteria 1RHN5@1224,2KGSW@204458,2U99J@28211,COG2332@1,COG2332@2 NA|NA|NA O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH MAG.T12.39_01855 450851.PHZ_c2693 1.8e-76 293.1 Caulobacterales cycH ko:K02200 ko00000 Bacteria 1MY4J@1224,2KH42@204458,2TSI7@28211,COG4235@1,COG4235@2 NA|NA|NA O Cytochrome c-type biogenesis protein MAG.T12.39_01856 450851.PHZ_c2695 6.9e-126 457.6 Caulobacterales phoQ 2.7.13.3 ko:K07637,ko:K07638,ko:K07717 ko01503,ko02020,ko02026,map01503,map02020,map02026 M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Bacteria 1QU2S@1224,2KJWA@204458,2TWVA@28211,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T12.39_01857 366602.Caul_3896 5.4e-84 317.4 Caulobacterales Bacteria 1N0YI@1224,2KFH0@204458,2TSV8@28211,COG0745@1,COG0745@2 NA|NA|NA KT Two component transcriptional regulator, winged helix family MAG.T12.39_01858 450851.PHZ_c2697 4.5e-15 87.4 Caulobacterales Bacteria 1NHDB@1224,2KHI3@204458,2V5I8@28211,COG3212@1,COG3212@2 NA|NA|NA S peptidase MAG.T12.39_01859 190650.CC_2772 5e-109 401.0 Caulobacterales dnaJ1 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 1MUZ4@1224,2KF75@204458,2TR01@28211,COG0484@1,COG0484@2,COG2214@1,COG2214@2 NA|NA|NA O chaperone DnaJ MAG.T12.39_01860 1121123.AUAO01000005_gene1834 2.4e-59 235.0 Caulobacterales ycgN ko:K09160 ko00000 Bacteria 1RHMX@1224,2KGGF@204458,2U99S@28211,COG2983@1,COG2983@2 NA|NA|NA S Belongs to the UPF0260 family MAG.T12.39_01861 59538.XP_005974400.1 1.6e-207 729.2 Cetartiodactyla Mammalia 3AHX4@33154,3BYSV@33208,3DFWV@33213,3JP49@40674,48SQ3@7711,49P7U@7742,4JCCE@91561,COG0488@1,KOG0927@2759 NA|NA|NA S ABC transporter F family member MAG.T12.39_01862 450851.PHZ_c2702 4e-123 448.0 Caulobacterales ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MXA3@1224,2KFXU@204458,2TTW8@28211,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like MAG.T12.39_01863 1449049.JONW01000008_gene364 1.6e-92 345.9 Caulobacterales ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MUIM@1224,2KG9B@204458,2TRHM@28211,COG1116@1,COG1116@2 NA|NA|NA P ABC transporter MAG.T12.39_01864 450851.PHZ_c2704 4.5e-95 354.4 Caulobacterales MA20_40340 ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MVAE@1224,2KG0E@204458,2TSP5@28211,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component MAG.T12.39_01865 366602.Caul_1258 1e-89 337.0 Caulobacterales Bacteria 1R3VY@1224,2KF51@204458,2TUQ8@28211,COG5330@1,COG5330@2 NA|NA|NA S Uncharacterised protein conserved in bacteria (DUF2336) MAG.T12.39_01866 509190.Cseg_0565 1.6e-136 492.3 Caulobacterales ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MVB0@1224,2KFFZ@204458,2TR1H@28211,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family MAG.T12.39_01867 450851.PHZ_c2852 8.5e-88 330.1 Caulobacterales Bacteria 1MY3D@1224,2KFCF@204458,2TSQF@28211,COG0745@1,COG0745@2 NA|NA|NA T Two component transcriptional regulator, winged helix family MAG.T12.39_01868 1449049.JONW01000005_gene1411 7.6e-154 550.4 Caulobacterales Bacteria 1MUAK@1224,2KFRB@204458,2TQRE@28211,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T12.39_01869 450851.PHZ_c2854 6.6e-35 153.7 Caulobacterales Bacteria 1N7E7@1224,2KK3C@204458,2UHSI@28211,COG4731@1,COG4731@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2147) MAG.T12.39_01870 450851.PHZ_c2855 2.9e-76 292.0 Caulobacterales proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1R5J1@1224,2KG94@204458,2TTY7@28211,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline MAG.T12.39_01871 450851.PHZ_c2856 3e-47 194.9 Caulobacterales MA20_05485 Bacteria 1REC1@1224,2KG9H@204458,2U7UP@28211,COG5465@1,COG5465@2 NA|NA|NA S Putative bacterial sensory transduction regulator MAG.T12.39_01872 1121022.ABENE_09040 6.8e-16 89.7 Caulobacterales yqiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K09806 ko00000 Bacteria 1Q2ES@1224,2KH5I@204458,2V666@28211,COG2960@1,COG2960@2 NA|NA|NA S Membrane fusogenic activity MAG.T12.39_01873 450851.PHZ_c2858 9.8e-96 356.7 Caulobacterales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1MVE3@1224,2KFY6@204458,2TTNS@28211,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T12.39_01874 450851.PHZ_c2859 1.2e-109 403.3 Caulobacterales MA20_05390 2.1.1.79 ko:K00574,ko:K18164 ko04714,map04714 ko00000,ko00001,ko01000,ko03029 Bacteria 1N3CJ@1224,2KF5M@204458,2TRHW@28211,COG1565@1,COG1565@2 NA|NA|NA S Putative S-adenosyl-L-methionine-dependent methyltransferase MAG.T12.39_01875 1449049.JONW01000006_gene3283 9.6e-77 293.5 Caulobacterales yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 1MW2H@1224,2KFZR@204458,2TTXU@28211,COG1496@1,COG1496@2 NA|NA|NA S Belongs to the multicopper oxidase YfiH RL5 family MAG.T12.39_01877 443598.AUFA01000026_gene1756 8.7e-29 132.5 Bradyrhizobiaceae yazA ko:K07461 ko00000 Bacteria 1N04N@1224,2UCN4@28211,3K0D8@41294,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain MAG.T12.39_01879 491916.RHECIAT_PC0000858 3e-74 285.4 Rhizobiaceae Bacteria 1Q8BS@1224,2BRCJ@1,2VEI1@28211,32KB8@2,4BJ3B@82115 NA|NA|NA MAG.T12.39_01880 1245469.S58_29940 1.5e-56 225.3 Bradyrhizobiaceae Bacteria 1RH8G@1224,2U9BR@28211,3JYZN@41294,COG0346@1,COG0346@2 NA|NA|NA E COG0346 Lactoylglutathione lyase and related lyases MAG.T12.39_01881 1122970.AUHC01000013_gene1053 3e-17 94.0 Sphingomonadales MA20_39405 ko:K09984 ko00000 Bacteria 1N712@1224,2K78J@204457,2UFME@28211,COG3813@1,COG3813@2 NA|NA|NA S protein conserved in bacteria MAG.T12.39_01882 1280954.HPO_02497 8.6e-26 122.1 Hyphomonadaceae Bacteria 1PEC2@1224,2UG6D@28211,440FC@69657,COG1773@1,COG1773@2 NA|NA|NA C rubredoxin MAG.T12.39_01883 1292034.OR37_02131 1.7e-208 731.9 Caulobacterales Bacteria 1MV8Q@1224,2KFJ6@204458,2TU15@28211,COG2124@1,COG2124@2 NA|NA|NA C cytochrome P450 MAG.T12.39_01884 450851.PHZ_c0064 1.9e-31 141.7 Caulobacterales ko:K22042 ko00000,ko03000 Bacteria 1N72Q@1224,2KJ72@204458,2UFSY@28211,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T12.39_01885 1110502.TMO_2286 5.1e-37 161.4 Proteobacteria ko:K09792 ko00000 Bacteria 1RIGJ@1224,COG2836@1,COG2836@2 NA|NA|NA P biogenesis protein MAG.T12.39_01886 59538.XP_005975011.1 3.6e-61 241.1 Opisthokonta YKL069W GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0033554,GO:0034599,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070191,GO:0070887 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Opisthokonta 2RXXR@2759,3A0D1@33154,COG1956@1 NA|NA|NA T GAF domain MAG.T12.39_01887 450851.PHZ_c2504 2.3e-183 648.3 Caulobacterales MA20_06750 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5G@1224,2KG3Y@204458,2TSA0@28211,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T12.39_01888 450851.PHZ_c2503 3.4e-73 281.6 Caulobacterales Bacteria 1N8G3@1224,2KGM6@204458,2TUTY@28211,COG1028@1,COG1028@2 NA|NA|NA IQ NAD dependent epimerase/dehydratase family MAG.T12.39_01889 69395.JQLZ01000004_gene739 5.7e-140 505.0 Caulobacterales Bacteria 1R0WC@1224,2KG78@204458,2U1A6@28211,COG1629@1,COG4771@2 NA|NA|NA P COG1629 Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_01890 450851.PHZ_c2500 5.4e-173 614.0 Caulobacterales sndH Bacteria 1MVK5@1224,2KF5F@204458,2TRN9@28211,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T12.39_01891 247634.GPB2148_560 4e-18 97.8 unclassified Gammaproteobacteria Bacteria 1JA48@118884,1RAEH@1224,1SERR@1236,COG3686@1,COG3686@2 NA|NA|NA S MAPEG family MAG.T12.39_01892 1537994.JQFW01000015_gene1777 9.7e-64 250.0 Proteobacteria 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1RESR@1224,COG4123@1,COG4123@2 NA|NA|NA S Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) MAG.T12.39_01893 1292034.OR37_01494 1.9e-24 118.2 Caulobacterales hupB ko:K03530,ko:K04764 ko00000,ko03032,ko03036,ko03400 Bacteria 1MZ5B@1224,2KJ4D@204458,2UC5G@28211,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions MAG.T12.39_01894 633149.Bresu_1072 1.7e-129 469.2 Caulobacterales dusA GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 ko:K05539,ko:K05540 ko00000,ko01000,ko03016 Bacteria 1MUY1@1224,2KEXC@204458,2TSRR@28211,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs MAG.T12.39_01895 509190.Cseg_1593 3.9e-31 141.4 Caulobacterales ko:K06985 ko04112,map04112 ko00000,ko00001 Bacteria 1MZCI@1224,2KH14@204458,2U9K2@28211,COG3577@1,COG3577@2 NA|NA|NA S gag-polyprotein putative aspartyl protease MAG.T12.39_01896 1333998.M2A_0798 4.2e-59 235.3 unclassified Alphaproteobacteria 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1R64Z@1224,2U0BA@28211,4BT4A@82117,COG1234@1,COG1234@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_01897 450851.PHZ_c2341 8.6e-23 112.5 Caulobacterales RSC1457 ko:K06938 ko00000 Bacteria 1NGD5@1224,2KH8U@204458,2UJKX@28211,COG3313@1,COG3313@2 NA|NA|NA S Protein of unknown function (DUF1289) MAG.T12.39_01899 450851.PHZ_c2336 2.2e-197 694.9 Caulobacterales Bacteria 1MVJC@1224,2KG7T@204458,2TQRA@28211,COG1960@1,COG1960@2 NA|NA|NA C Acyl-CoA dehydrogenase, middle domain MAG.T12.39_01900 450851.PHZ_c2335 1.6e-176 625.5 Caulobacterales Bacteria 1MUBH@1224,2KG7J@204458,2TSKH@28211,COG1960@1,COG1960@2 NA|NA|NA C PFAM Acyl-CoA dehydrogenase MAG.T12.39_01901 1304885.AUEY01000023_gene2664 9.9e-37 160.2 Desulfobacterales Bacteria 1RD76@1224,2MNYB@213118,2WP23@28221,42MR0@68525,COG0663@1,COG0663@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) MAG.T12.39_01902 190650.CC_2568 2.5e-89 335.5 Caulobacterales ko:K15268 ko00000,ko02000 2.A.7.3.2 Bacteria 1MVKG@1224,2KGU9@204458,2U30N@28211,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T12.39_01903 69395.JQLZ01000012_gene4333 5.2e-101 374.0 Caulobacterales amiD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 ko:K00788,ko:K01447 ko00730,ko01100,map00730,map01100 M00127 R03223,R04112,R10712 RC00064,RC00141,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDHU@1224,2KEZK@204458,2TSW3@28211,COG3023@1,COG3023@2 NA|NA|NA V N-acetylmuramoyl-L-alanine amidase MAG.T12.39_01904 1333998.M2A_2378 7.6e-33 147.1 Alphaproteobacteria ynaD1 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1N619@1224,2UDSR@28211,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T12.39_01905 450851.PHZ_c2332 2.9e-71 274.6 Caulobacterales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1RBYS@1224,2KGEA@204458,2VA3C@28211,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family MAG.T12.39_01906 509190.Cseg_1126 7.4e-116 423.7 Caulobacterales rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1MUT4@1224,2KEYQ@204458,2TRQA@28211,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA MAG.T12.39_01907 450851.PHZ_c2330 3.2e-16 91.7 Caulobacterales MA20_01770 Bacteria 1N8GV@1224,2KH6U@204458,2UF7Y@28211,COG5462@1,COG5462@2 NA|NA|NA S secreted (periplasmic) protein MAG.T12.39_01908 450851.PHZ_c2329 5.6e-165 587.8 Caulobacterales ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1MUNY@1224,2KF8N@204458,2TSHQ@28211,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein MAG.T12.39_01909 450851.PHZ_c2328 9.6e-171 606.7 Caulobacterales murE 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1MU6P@1224,2KFZM@204458,2TVXI@28211,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T12.39_01910 450851.PHZ_c2327 8.7e-169 600.1 Caulobacterales murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1QTSF@1224,2KF78@204458,2TR0Q@28211,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein MAG.T12.39_01911 450851.PHZ_c2326 2.2e-159 568.5 Caulobacterales mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1MUTK@1224,2KF3B@204458,2TRUG@28211,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan MAG.T12.39_01912 69395.JQLZ01000012_gene4342 4.3e-200 704.1 Caulobacterales murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1MVYD@1224,2KF97@204458,2TTE8@28211,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) MAG.T12.39_01913 450851.PHZ_c2324 2.9e-170 604.7 Caulobacterales ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 1MVDB@1224,2KG14@204458,2TQSA@28211,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T12.39_01914 450851.PHZ_c2323 4.5e-144 517.7 Caulobacterales murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1MVIB@1224,2KFCP@204458,2TSEY@28211,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) MAG.T12.39_01915 450851.PHZ_c2322 5.4e-219 766.9 Caulobacterales murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.45,6.3.2.8 ko:K01924,ko:K02558 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iECP_1309.ECP_0093,iJN678.murC Bacteria 1MV68@1224,2KF3H@204458,2TRT0@28211,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family MAG.T12.39_01916 450851.PHZ_c2321 1.2e-121 443.0 Caulobacterales murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1MXDH@1224,2KFM4@204458,2TRQR@28211,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation MAG.T12.39_01917 450851.PHZ_c2317 8.4e-131 473.4 Caulobacterales ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 iECO26_1355.ECO26_0095 Bacteria 1MUTB@1224,2KFYN@204458,2TREC@28211,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family MAG.T12.39_01918 450851.PHZ_c2316 4.1e-71 275.0 Caulobacterales ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 1MY1Q@1224,2KGMJ@204458,2TQPU@28211,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein FtsQ MAG.T12.39_01919 450851.PHZ_c2315 4e-192 677.6 Caulobacterales ftsA ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1MUSR@1224,2KFSG@204458,2TQZB@28211,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring MAG.T12.39_01920 366602.Caul_3657 1.4e-175 622.9 Caulobacterales ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1MV2X@1224,2KF35@204458,2TS1Q@28211,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity MAG.T12.39_01921 450851.PHZ_c2312 5.2e-119 434.1 Caulobacterales lpxC 3.5.1.108,4.2.1.59 ko:K02535,ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 M00060,M00083 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1MV6T@1224,2KF0U@204458,2TUHH@28211,COG0774@1,COG0774@2 NA|NA|NA M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis MAG.T12.39_01922 450851.PHZ_c2311 5.6e-113 414.1 Caulobacterales bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria 1MVS5@1224,2KF5H@204458,2TRZ5@28211,COG4105@1,COG4105@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T12.39_01923 1382303.JPOM01000001_gene1050 2.7e-156 558.9 Caulobacterales recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03631 ko00000,ko03400 Bacteria 1MUNP@1224,2KF2G@204458,2TREW@28211,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA MAG.T12.39_01924 450851.PHZ_c2309 1.3e-304 1052.0 Caulobacterales ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1MV3R@1224,2KFXN@204458,2TRHK@28211,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T12.39_01925 1088721.NSU_3291 1.1e-88 333.6 Sphingomonadales ybeL 1.17.4.1,4.6.1.1 ko:K00525,ko:K01768 ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213 M00053,M00695 R00089,R00434,R02017,R02018,R02019,R02024 RC00295,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1R0VS@1224,2K9UJ@204457,2U4X8@28211,COG2888@1,COG2888@2 NA|NA|NA J peptidyl-tyrosine sulfation MAG.T12.39_01927 450851.PHZ_c2307 1.4e-251 875.5 Caulobacterales pepP 3.4.11.9 ko:K01262,ko:K02027 M00207 ko00000,ko00002,ko01000,ko01002,ko02000 3.A.1.1 Bacteria 1MUZS@1224,2KFE0@204458,2TQXN@28211,COG0006@1,COG0006@2 NA|NA|NA E C-terminal region of peptidase_M24 MAG.T12.39_01928 1038862.KB893917_gene4436 3.7e-20 104.4 Bradyrhizobiaceae Bacteria 1N8HB@1224,2UGZ1@28211,3JZJI@41294,COG3860@1,COG3860@2 NA|NA|NA S Transcriptional regulator MAG.T12.39_01929 450851.PHZ_c2304 1.4e-116 426.0 Caulobacterales prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1MUPC@1224,2KG69@204458,2TTP3@28211,COG2264@1,COG2264@2 NA|NA|NA J Methylates ribosomal protein L11 MAG.T12.39_01931 69395.JQLZ01000003_gene200 1.1e-84 320.1 Alphaproteobacteria Bacteria 1R41P@1224,2TRY2@28211,COG2267@1,COG2267@2 NA|NA|NA I Alpha beta hydrolase MAG.T12.39_01932 450851.PHZ_c2302 0.0 1197.6 Caulobacterales uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU0G@1224,2KEYX@204458,2TS2B@28211,COG0210@1,COG0210@2 NA|NA|NA L helicase MAG.T12.39_01933 1121123.AUAO01000003_gene2270 2.1e-15 87.8 Caulobacterales MA20_02235 Bacteria 1PV4X@1224,2KH7E@204458,2V6KV@28211,COG4321@1,COG4321@2 NA|NA|NA S Ribbon-helix-helix domain MAG.T12.39_01934 450851.PHZ_c2295 8.3e-94 350.1 Caulobacterales ko:K18586 ko00000 Bacteria 1RGXT@1224,2KGHQ@204458,2U8F1@28211,COG5031@1,COG5031@2 NA|NA|NA H Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MAG.T12.39_01935 450851.PHZ_c2280 6.7e-151 540.4 Caulobacterales mrdB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K05837 ko00000,ko03036 Bacteria 1MUK3@1224,2KFNQ@204458,2TSM0@28211,COG0772@1,COG0772@2 NA|NA|NA M Peptidoglycan polymerase that is essential for cell wall elongation MAG.T12.39_01936 450851.PHZ_c2281 1.3e-239 835.9 Caulobacterales mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 Bacteria 1MV8C@1224,2KEY2@204458,2TRXN@28211,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding protein 2 MAG.T12.39_01937 69395.JQLZ01000001_gene2599 1.7e-34 152.5 Caulobacterales ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1RIMJ@1224,2BGH0@1,2KGW0@204458,2UBCP@28211,32AF1@2 NA|NA|NA MAG.T12.39_01938 1081640.AGFU01000026_gene2599 1.5e-14 86.3 Sphingomonadales Bacteria 1PVV8@1224,2FIA7@1,2KATX@204457,2V733@28211,315NI@2 NA|NA|NA MAG.T12.39_01939 450851.PHZ_c0438 8e-87 326.6 Caulobacterales metW 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 1MVSY@1224,2KFNH@204458,2TTNQ@28211,COG0500@1,COG2226@2 NA|NA|NA Q TIGRFAM methionine biosynthesis protein MetW MAG.T12.39_01940 450851.PHZ_c0439 1.6e-181 642.1 Caulobacterales metXA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 1MVJV@1224,2KG3V@204458,2TQYA@28211,COG2021@1,COG2021@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine MAG.T12.39_01941 450851.PHZ_c0440 8.6e-39 166.8 Caulobacterales sixA ko:K08296 ko00000,ko01000 Bacteria 1N0FX@1224,2KH0J@204458,2UBYD@28211,COG2062@1,COG2062@2 NA|NA|NA T phosphohistidine phosphatase MAG.T12.39_01942 450851.PHZ_c0441 6.1e-36 156.8 Caulobacterales MA20_22095 ko:K12979 ko00000,ko01000,ko01005 Bacteria 1MZEQ@1224,2KH1Q@204458,2UBR3@28211,COG3502@1,COG3502@2 NA|NA|NA S Protein of unknown function (DUF952) MAG.T12.39_01943 450851.PHZ_c0442 5.7e-133 480.7 Caulobacterales pyrD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.1.14,1.3.5.2,1.3.98.1 ko:K00226,ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU7C@1224,2KF41@204458,2TRF8@28211,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor MAG.T12.39_01944 450851.PHZ_c0443 1.7e-162 579.3 Caulobacterales pilS 2.7.13.3 ko:K02668 ko02020,map02020 M00501 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1MVK7@1224,2KFAJ@204458,2TR44@28211,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T12.39_01945 450851.PHZ_c3353 1.3e-44 186.0 Caulobacterales Bacteria 1RITY@1224,2KGIY@204458,2U98M@28211,COG0789@1,COG0789@2 NA|NA|NA K Regulator MAG.T12.39_01946 450851.PHZ_c3354 2.5e-261 907.9 Caulobacterales acd 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU20@1224,2KF67@204458,2TQJS@28211,COG1960@1,COG1960@2 NA|NA|NA C acyl-CoA dehydrogenase MAG.T12.39_01947 441620.Mpop_4785 1.7e-44 185.7 Methylobacteriaceae ymaD ko:K04063 ko00000 Bacteria 1JUFU@119045,1RI5C@1224,2U99X@28211,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein MAG.T12.39_01948 450851.PHZ_c3356 1.3e-51 209.1 Caulobacterales vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 1RH1C@1224,2KGWM@204458,2UA6G@28211,COG3727@1,COG3727@2 NA|NA|NA L May nick specific sequences that contain T G mispairs resulting from m5C-deamination MAG.T12.39_01949 450851.PHZ_c3357 2.4e-149 535.0 Caulobacterales cysK 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUBE@1224,2KF9V@204458,2TS33@28211,COG0031@1,COG0031@2 NA|NA|NA E Cysteine synthase MAG.T12.39_01950 450851.PHZ_c3358 5.8e-131 474.2 Caulobacterales dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1MV9H@1224,2KFNE@204458,2TTZG@28211,COG0270@1,COG0270@2 NA|NA|NA L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family MAG.T12.39_01951 1280948.HY36_14990 8.5e-32 142.9 Hyphomonadaceae ybjQ Bacteria 1N0XM@1224,2UCR7@28211,43ZZB@69657,COG0393@1,COG0393@2 NA|NA|NA S Putative heavy-metal-binding MAG.T12.39_01952 450851.PHZ_c3360 3.9e-251 874.0 Caulobacterales MA20_22865 Bacteria 1MWWY@1224,2KFGN@204458,2TSZZ@28211,COG3653@1,COG3653@2 NA|NA|NA Q Amidohydrolase family MAG.T12.39_01953 450851.PHZ_c3361 1e-233 816.2 Caulobacterales recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVGG@1224,2KFEG@204458,2TS8B@28211,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ MAG.T12.39_01954 450851.PHZ_c3370 0.0 1369.8 Caulobacterales gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 1MVKT@1224,2KEY3@204458,2TRBK@28211,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T12.39_01955 450851.PHZ_c3385 1.4e-140 506.1 Caulobacterales recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1MX8N@1224,2KG1Y@204458,2TQRD@28211,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP MAG.T12.39_01956 450851.PHZ_c3468 7.9e-173 613.2 Caulobacterales dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MVD9@1224,2KFSH@204458,2TSRZ@28211,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria MAG.T12.39_01957 450851.PHZ_c3469 3.3e-53 214.9 Caulobacterales grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1RH8T@1224,2KGJU@204458,2U5V2@28211,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MAG.T12.39_01958 450851.PHZ_c3470 1e-145 523.1 Caulobacterales hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1MVX4@1224,2KFFK@204458,2TRUF@28211,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons MAG.T12.39_01959 450851.PHZ_c3471 5.6e-103 380.6 Caulobacterales rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 1MVFZ@1224,2KFPN@204458,2TRMC@28211,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates MAG.T12.39_01961 1229204.AMYY01000008_gene1830 3.4e-18 97.1 Alphaproteobacteria yozG ko:K07727 ko00000,ko03000 Bacteria 1N6VH@1224,2UFAM@28211,COG3655@1,COG3655@2 NA|NA|NA K transcriptional regulator MAG.T12.39_01962 450851.PHZ_c3473 3e-37 161.8 Caulobacterales Bacteria 1MZ9P@1224,2DZQF@1,2KGZ4@204458,2UDR3@28211,32VG9@2 NA|NA|NA S Protein of unknown function (DUF2975) MAG.T12.39_01963 450851.PHZ_c3474 5.3e-75 287.3 Caulobacterales rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1MUK5@1224,2KFDW@204458,2TV4B@28211,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions MAG.T12.39_01964 450851.PHZ_c3475 2.4e-124 452.2 Caulobacterales yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 Bacteria 1MU76@1224,2KG4C@204458,2TT63@28211,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound MAG.T12.39_01965 450851.PHZ_c3476 9.3e-97 360.1 Caulobacterales rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1MU0E@1224,2KFTN@204458,2TR14@28211,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA MAG.T12.39_01966 450851.PHZ_c3477 2.2e-37 161.8 Caulobacterales MA20_24645 ko:K07460 ko00000 Bacteria 1N6VN@1224,2KH4W@204458,2UFTM@28211,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family MAG.T12.39_01967 450851.PHZ_c3479 8.3e-131 473.4 Caulobacterales gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2,6.3.2.3 ko:K01919,ko:K01920,ko:K05844 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R00894,R10993,R10994 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko03009 iECED1_1282.ECED1_3410,iECP_1309.ECP_2941,iJN678.gshB Bacteria 1MVUA@1224,2KFT8@204458,2TQNE@28211,COG0189@1,COG0189@2 NA|NA|NA H Belongs to the prokaryotic GSH synthase family MAG.T12.39_01968 450851.PHZ_c3480 2.2e-194 685.3 Caulobacterales comM ko:K07391 ko00000 Bacteria 1MU4R@1224,2KFQM@204458,2TQU6@28211,COG0606@1,COG0606@2 NA|NA|NA O chelatase, subunit ChlI MAG.T12.39_01969 450851.PHZ_c3484 1.4e-143 516.5 Caulobacterales 2.7.13.3 ko:K20974 ko02020,ko02025,map02020,map02025 M00820 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1NRP8@1224,2KG7F@204458,2TYDC@28211,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T12.39_01970 391600.ABRU01000060_gene1521 1.8e-160 572.8 Caulobacterales ampG ko:K02445,ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25,2.A.1.4.3 Bacteria 1QUF4@1224,2KGKY@204458,2TW2A@28211,COG2271@1,COG2271@2 NA|NA|NA G major facilitator superfamily MAG.T12.39_01971 450851.PHZ_c3446 1.1e-79 302.8 Caulobacterales ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iJN746.PP_0538,iPC815.YPO3521 Bacteria 1RA2F@1224,2KG8D@204458,2TQZM@28211,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions MAG.T12.39_01972 450851.PHZ_c3442 3.7e-70 271.2 Caulobacterales rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1RDP2@1224,2KGBX@204458,2TS4E@28211,COG0779@1,COG0779@2 NA|NA|NA S Required for maturation of 30S ribosomal subunits MAG.T12.39_01973 450851.PHZ_c3441 1e-253 882.5 Caulobacterales nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 1MWT7@1224,2KF7D@204458,2TRQN@28211,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination MAG.T12.39_01975 450851.PHZ_c3439 0.0 1216.8 Caulobacterales infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1MV26@1224,2KFWC@204458,2TQMY@28211,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex MAG.T12.39_01976 450851.PHZ_c3437 5.8e-46 190.7 Caulobacterales Bacteria 1NYNP@1224,2F6VI@1,2KIYJ@204458,2UTE4@28211,33ZBP@2 NA|NA|NA S Protein of unknown function (DUF2939) MAG.T12.39_01977 450851.PHZ_c3436 1.4e-91 342.8 Caulobacterales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1PSEB@1224,2KI39@204458,2TTN4@28211,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T12.39_01978 450851.PHZ_c3435 1.5e-47 195.7 Caulobacterales rbfA ko:K02834 ko00000,ko03009 Bacteria 1MZPE@1224,2KGRM@204458,2UCJF@28211,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA MAG.T12.39_01979 450851.PHZ_c3434 5.3e-130 470.7 Caulobacterales truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 1MV0N@1224,2KFRC@204458,2TSJK@28211,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs MAG.T12.39_01980 190650.CC_0035 4.1e-35 153.7 Caulobacterales rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ2W@1224,2KGYC@204458,2UBRZ@28211,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome MAG.T12.39_01981 450851.PHZ_c3432 0.0 1190.3 Caulobacterales pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1MVB9@1224,2KF6S@204458,2TRH3@28211,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction MAG.T12.39_01982 272630.MexAM1_META1p3479 8.5e-48 196.8 Alphaproteobacteria Bacteria 1RH83@1224,2U9BI@28211,COG3860@1,COG3860@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2087) MAG.T12.39_01983 450851.PHZ_c3431 3.4e-208 731.1 Caulobacterales dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1MU5H@1224,2KFU8@204458,2TT03@28211,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T12.39_01984 391600.ABRU01000015_gene3084 1.4e-30 138.7 Caulobacterales rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ94@1224,2KGX2@204458,2UC42@28211,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA MAG.T12.39_01985 59538.XP_005973544.1 3.7e-113 414.5 Cetartiodactyla Mammalia 38F58@33154,3BC2F@33208,3D1QF@33213,3JEMZ@40674,487TD@7711,48X6A@7742,4J02R@91561,COG1024@1,KOG1680@2759 NA|NA|NA I enoyl-CoA hydratase MAG.T12.39_01986 450851.PHZ_c3427 2e-112 412.1 Caulobacterales fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVM5@1224,2KF40@204458,2TS4C@28211,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates MAG.T12.39_01987 450851.PHZ_c3426 3.3e-114 417.9 Caulobacterales ubiE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX8I@1224,2KFN8@204458,2TRWR@28211,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) MAG.T12.39_01988 450851.PHZ_c3425 9.6e-174 616.7 Caulobacterales ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 ko:K03688 ko00000 iYL1228.KPN_04331 Bacteria 1MU1Z@1224,2KFX9@204458,2TS87@28211,COG0661@1,COG0661@2 NA|NA|NA S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis MAG.T12.39_01989 450851.PHZ_c3424 1.8e-30 139.4 Caulobacterales ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1N5ZS@1224,2KGWW@204458,2UE25@28211,COG5529@1,COG5529@2 NA|NA|NA MAG.T12.39_01990 450851.PHZ_c3423 7.2e-156 557.0 Caulobacterales coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 Bacteria 1MVQP@1224,2KFK7@204458,2TRN1@28211,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine MAG.T12.39_01991 450851.PHZ_c3422 4.6e-55 220.7 Caulobacterales dut GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0865,iYO844.BSU17660 Bacteria 1RA7P@1224,2KGMZ@204458,2U7B5@28211,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA MAG.T12.39_01992 2074.JNYD01000003_gene4102 9.9e-34 150.2 Pseudonocardiales gpm 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM22@201174,4E6PX@85010,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family MAG.T12.39_01993 1313172.YM304_13600 4.4e-51 208.8 Actinobacteria Bacteria 2GN8T@201174,COG3178@1,COG3178@2 NA|NA|NA S Ecdysteroid kinase MAG.T12.39_01994 1280954.HPO_16875 1.9e-23 114.8 Hyphomonadaceae ko:K07729 ko00000,ko03000 Bacteria 1N7BB@1224,2UGNF@28211,43YR8@69657,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain MAG.T12.39_01995 1280941.HY2_04095 1.7e-13 82.4 Hyphomonadaceae Bacteria 1NJTQ@1224,2FFPQ@1,2UKIJ@28211,347M1@2,43YZA@69657 NA|NA|NA MAG.T12.39_01996 190650.CC_3550 3.3e-85 321.6 Caulobacterales dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215,ko:K03546 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0510,iLJ478.TM1520,iSbBS512_1146.SbBS512_E0035 Bacteria 1MUCT@1224,2KG8A@204458,2TSFJ@28211,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate MAG.T12.39_01997 633149.Bresu_0276 8.7e-138 496.5 Caulobacterales clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1MURH@1224,2KF39@204458,2TRKI@28211,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE MAG.T12.39_01998 460265.Mnod_4768 7.9e-41 173.3 Methylobacteriaceae yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 ko:K15034 ko00000,ko03012 Bacteria 1JUJ6@119045,1RH75@1224,2U9M7@28211,COG1186@1,COG1186@2 NA|NA|NA J Class I peptide chain release factor MAG.T12.39_01999 450851.PHZ_c0822 1.2e-53 216.1 Caulobacterales zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1MZIW@1224,2KGRQ@204458,2U9G4@28211,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family MAG.T12.39_02001 450851.PHZ_c0827 5.8e-115 420.6 Caulobacterales prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297,2.1.1.4 ko:K00543,ko:K02493,ko:K15256 ko00380,ko01100,map00380,map01100 M00037 R03130,R04905,R10806 RC00003,RC00392,RC03279 ko00000,ko00001,ko00002,ko01000,ko03012,ko03016 Bacteria 1MXCQ@1224,2KG3D@204458,2TZFK@28211,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif MAG.T12.39_02002 450851.PHZ_c0828 2.4e-75 288.9 Caulobacterales ko:K07140 ko00000 Bacteria 1MVSP@1224,2KFDN@204458,2U1ST@28211,COG3217@1,COG3217@2 NA|NA|NA S MOSC domain protein beta barrel domain protein MAG.T12.39_02003 450851.PHZ_c0833 1.1e-160 572.8 Caulobacterales prfA ko:K02835 ko00000,ko03012 Bacteria 1MV28@1224,2KFY7@204458,2TQSV@28211,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA MAG.T12.39_02004 450851.PHZ_c0835 7.4e-30 136.3 Alphaproteobacteria Bacteria 1RH06@1224,2E6S2@1,2U98E@28211,331C5@2 NA|NA|NA MAG.T12.39_02005 450851.PHZ_c0836 5.3e-177 627.1 Caulobacterales ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 Bacteria 1MUAX@1224,2KFD6@204458,2TQSI@28211,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate MAG.T12.39_02006 69395.JQLZ01000003_gene382 1.5e-55 223.4 Caulobacterales ko:K15539 ko00000 Bacteria 1MYWX@1224,2KGH6@204458,2U8C2@28211,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain MAG.T12.39_02007 450851.PHZ_c0839 0.0 1250.0 Caulobacterales ptsP 2.7.13.3,2.7.3.9 ko:K07683,ko:K08484,ko:K10851 ko02020,ko02060,map02020,map02060 M00483 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 Bacteria 1QTTV@1224,2KF7C@204458,2TR3Z@28211,COG3605@1,COG3605@2 NA|NA|NA T Belongs to the PEP-utilizing enzyme family MAG.T12.39_02008 1123240.ATVO01000009_gene770 4.9e-43 181.4 Sphingomonadales phoC GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.1.3.2 ko:K09474 ko00740,ko01100,ko02020,map00740,map01100,map02020 R00548 RC00017 ko00000,ko00001,ko01000 Bacteria 1PM2D@1224,2KDY3@204457,2VEZ3@28211,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase MAG.T12.39_02009 1342299.Z947_187 5.2e-123 448.4 Sulfitobacter ko:K06889 ko00000 Bacteria 1PUZN@1224,2V6GW@28211,3ZY9T@60136,COG1073@1,COG1073@2 NA|NA|NA S X-Pro dipeptidyl-peptidase (S15 family) MAG.T12.39_02010 450851.PHZ_c0841 4.6e-198 697.2 Caulobacterales lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW3H@1224,2KFIQ@204458,2TRFA@28211,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family MAG.T12.39_02011 450851.PHZ_c0842 7.3e-106 390.2 Caulobacterales ubiG 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU89@1224,2KFT0@204458,2TRIK@28211,COG2227@1,COG2227@2 NA|NA|NA H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway MAG.T12.39_02012 338969.Rfer_1006 4.3e-172 611.3 Comamonadaceae alkK 6.2.1.44 ko:K00666,ko:K20034 ko00920,map00920 R10820 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 Bacteria 1MUMC@1224,2VGZE@28216,4AA4Q@80864,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T12.39_02013 450851.PHZ_c0845 2.7e-170 604.7 Caulobacterales MA20_19250 1.1.1.1,1.1.1.284,1.1.1.306 ko:K00121,ko:K00153 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310,R09129,R10301 RC00050,RC00069,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MUK4@1224,2KFD3@204458,2TU1G@28211,COG1062@1,COG1062@2 NA|NA|NA C alcohol dehydrogenase MAG.T12.39_02014 450851.PHZ_c0849 7.7e-34 149.8 Caulobacterales arsC 1.20.4.1 ko:K00537 ko00000,ko01000 Bacteria 1MZ4Z@1224,2KHI6@204458,2U70U@28211,COG1393@1,COG1393@2 NA|NA|NA P ArsC family MAG.T12.39_02015 450851.PHZ_c0850 3.3e-168 599.0 Caulobacterales Bacteria 1R56X@1224,2KFTP@204458,2U2G7@28211,COG2234@1,COG2234@2 NA|NA|NA S peptidase MAG.T12.39_02016 450851.PHZ_c0851 4.5e-118 430.6 Caulobacterales Bacteria 1MWVI@1224,2KFGK@204458,2TRSP@28211,COG0745@1,COG0745@2 NA|NA|NA K PFAM response regulator receiver MAG.T12.39_02018 450851.PHZ_c0853 7.6e-215 753.1 Caulobacterales fliI 3.6.3.14 ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1MUH6@1224,2KF06@204458,2TRXU@28211,COG1157@1,COG1157@2 NA|NA|NA NU Involved in type III protein export during flagellum assembly MAG.T12.39_02019 450851.PHZ_c0854 3.4e-28 131.3 Caulobacterales fliJ ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZRI@1224,2D3G6@1,2KH0F@204458,2UC2C@28211,32TEW@2 NA|NA|NA N flagellar export protein FliJ MAG.T12.39_02020 190650.CC_0914 9e-25 119.8 Caulobacterales Bacteria 1NFPR@1224,2CG0M@1,2KH7A@204458,2UHAR@28211,33796@2 NA|NA|NA S Domain of unknown function (DUF4282) MAG.T12.39_02021 450851.PHZ_c0857 1.9e-305 1054.7 Caulobacterales flhA ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1MUF3@1224,2KFR0@204458,2TQUR@28211,COG1298@1,COG1298@2 NA|NA|NA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin MAG.T12.39_02022 450851.PHZ_c0858 1.1e-211 742.7 Caulobacterales flbD ko:K10943 ko02020,ko05111,map02020,map05111 M00515 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KG02@204458,2TQPG@28211,COG2204@1,COG2204@2 NA|NA|NA K Two component, sigma54 specific, transcriptional regulator, Fis family MAG.T12.39_02023 450851.PHZ_c0859 2.4e-37 161.4 Caulobacterales fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1RGWT@1224,2KH2D@204458,2UC6U@28211,COG1886@1,COG1886@2 NA|NA|NA N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation MAG.T12.39_02024 190650.CC_0907 2.6e-51 208.8 Caulobacterales fliH ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1N39Q@1224,2KH6V@204458,2V6G4@28211,COG1317@1,COG1317@2 NA|NA|NA N bacterial-type flagellum organization MAG.T12.39_02025 633149.Bresu_2812 1.1e-152 546.2 Caulobacterales fliG GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0046982,GO:0046983,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 Bacteria 1MV9X@1224,2KF0X@204458,2TRIV@28211,COG1536@1,COG1536@2 NA|NA|NA N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation MAG.T12.39_02026 450851.PHZ_c0862 4e-194 684.5 Caulobacterales fliF ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1MUQR@1224,2KFS2@204458,2TR6J@28211,COG1766@1,COG1766@2 NA|NA|NA N The M ring may be actively involved in energy transduction MAG.T12.39_02027 450851.PHZ_c0863 1.5e-182 646.4 Caulobacterales Bacteria 1PQ2Z@1224,2KFJC@204458,2U2RD@28211,COG1680@1,COG1680@2 NA|NA|NA V beta-lactamase MAG.T12.39_02028 450851.PHZ_c0864 2.2e-81 308.9 Caulobacterales Bacteria 1QU7W@1224,2KGH3@204458,2U7FJ@28211,COG4249@1,COG4249@2 NA|NA|NA S Peptidase C13 family MAG.T12.39_02029 450851.PHZ_c0865 1.3e-66 259.2 Caulobacterales Bacteria 1RF3N@1224,2KGW5@204458,2U9D7@28211,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T12.39_02030 450851.PHZ_c0866 2.1e-50 205.3 Caulobacterales MA20_02250 ko:K09985 ko00000 Bacteria 1N1FE@1224,2KGFD@204458,2U7H9@28211,COG3814@1,COG3814@2 NA|NA|NA S Stringent starvation protein B MAG.T12.39_02032 366602.Caul_3356 4e-84 317.8 Caulobacterales aqpZ ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 1MXTJ@1224,2KI28@204458,2TRGG@28211,COG0580@1,COG0580@2 NA|NA|NA G Major intrinsic protein MAG.T12.39_02033 450851.PHZ_c0867 2e-76 292.0 Caulobacterales ilvH GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1906,iECNA114_1301.ECNA114_0072,iEcSMS35_1347.EcSMS35_0084,iG2583_1286.G2583_0082,iSFxv_1172.SFxv_0077,iUTI89_1310.UTI89_C0086 Bacteria 1RAGN@1224,2KGE9@204458,2U5CW@28211,COG0440@1,COG0440@2 NA|NA|NA E Acetolactate synthase, small subunit MAG.T12.39_02034 450851.PHZ_c3315 7.1e-38 163.7 Caulobacterales 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1QU3V@1224,2KK9B@204458,2TVYC@28211,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T12.39_02035 1030157.AFMP01000062_gene3589 1.9e-51 209.1 Sphingomonadales 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1RGF5@1224,2K19C@204457,2U980@28211,COG0652@1,COG0652@2 NA|NA|NA M peptidyl-prolyl cis-trans isomerase MAG.T12.39_02036 1449049.JONW01000005_gene1844 1.1e-127 464.5 Proteobacteria 2.7.13.3 ko:K07679 ko02020,ko05133,map02020,map05133 M00477 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1NXDJ@1224,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase MAG.T12.39_02037 522306.CAP2UW1_0178 1.5e-54 219.2 unclassified Betaproteobacteria ko:K09983 ko00000 Bacteria 1KR5A@119066,1RGUV@1224,2WA8Z@28216,COG3812@1,COG3812@2 NA|NA|NA S Domain of unknown function (DUF1993) MAG.T12.39_02038 1114964.L485_20590 4.9e-28 131.3 Sphingomonadales Bacteria 1Q6FV@1224,2KBX9@204457,2VBS2@28211,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) MAG.T12.39_02039 349102.Rsph17025_1918 1.4e-23 116.7 Rhodobacter yedK Bacteria 1FD4Q@1060,1N9TF@1224,2VG2C@28211,COG2135@1,COG2135@2 NA|NA|NA S Belongs to the SOS response-associated peptidase family MAG.T12.39_02040 450851.PHZ_c0873 4.7e-292 1010.0 Caulobacterales ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU6U@1224,2KEXP@204458,2TR1I@28211,COG0028@1,COG0028@2 NA|NA|NA H acetolactate synthase large subunit MAG.T12.39_02041 450851.PHZ_c0874 6e-102 377.5 Caulobacterales miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1MUB2@1224,2KEXK@204458,2TR8Z@28211,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) MAG.T12.39_02042 450851.PHZ_c0875 1.6e-77 295.8 Caulobacterales serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95,3.1.3.3 ko:K00058,ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582,R01513 RC00017,RC00031 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 Bacteria 1MWA3@1224,2KG1M@204458,2TSEU@28211,COG0560@1,COG0560@2 NA|NA|NA E phosphoserine phosphatase MAG.T12.39_02043 1353531.AZNX01000003_gene2687 1.2e-67 263.1 Rhizobiaceae 3.1.3.96 ko:K17623 R11180 RC00017 ko00000,ko01000,ko01009 Bacteria 1NF90@1224,2U9G8@28211,4BFSG@82115,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase MAG.T12.39_02044 450851.PHZ_c0879 2e-123 449.1 Caulobacterales ko:K03593 ko00000,ko03029,ko03036 Bacteria 1MU7R@1224,2KFWN@204458,2TRDM@28211,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP MAG.T12.39_02045 450851.PHZ_c0880 1.6e-125 456.4 Caulobacterales ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2KFG7@204458,2U1DI@28211,COG2211@1,COG2211@2 NA|NA|NA G PFAM major facilitator superfamily MFS_1 MAG.T12.39_02046 1382303.JPOM01000001_gene862 4e-135 487.6 Caulobacterales Bacteria 1MXNQ@1224,2KFIJ@204458,2TS6G@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T12.39_02047 450851.PHZ_c0882 7.1e-90 337.4 Caulobacterales ko:K01993,ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1R71G@1224,2KF14@204458,2TV4Y@28211,COG0845@1,COG0845@2 NA|NA|NA M Secretion protein MAG.T12.39_02048 366602.Caul_3339 2.7e-78 298.5 Caulobacterales hrtA ko:K02003,ko:K09814 ko02010,map02010 M00257,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 1QU8Q@1224,2KFU9@204458,2TWD6@28211,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T12.39_02049 450851.PHZ_c0884 2.3e-95 355.9 Caulobacterales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1NWI3@1224,2KFQJ@204458,2U2NH@28211,COG0577@1,COG0577@2 NA|NA|NA V COG0577 ABC-type antimicrobial peptide transport system permease component MAG.T12.39_02050 69395.JQLZ01000001_gene2776 1.1e-257 896.0 Caulobacterales Bacteria 1MX71@1224,2KF5T@204458,2U2MN@28211,COG3591@1,COG3591@2 NA|NA|NA E Peptidase S46 MAG.T12.39_02052 450851.PHZ_c1922 2.3e-185 655.2 Caulobacterales murC 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1MUC5@1224,2KI4K@204458,2TUQZ@28211,COG0773@1,COG0773@2 NA|NA|NA M Mur ligase family, catalytic domain MAG.T12.39_02053 228405.HNE_2392 3.8e-153 547.7 Alphaproteobacteria Bacteria 1R6GW@1224,28M2T@1,2U25T@28211,2ZAH6@2 NA|NA|NA MAG.T12.39_02055 1121123.AUAO01000004_gene1660 2.4e-72 278.9 Caulobacterales rluF 5.4.99.21 ko:K06182 ko00000,ko01000,ko03009 Bacteria 1MXQE@1224,2KFRQ@204458,2U42J@28211,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T12.39_02056 1300345.LF41_707 3.8e-66 259.2 Xanthomonadales macA_1 ko:K02005,ko:K13888 M00709 ko00000,ko00002,ko02000 8.A.1 Bacteria 1MU8D@1224,1RN0E@1236,1X5W6@135614,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T12.39_02057 1356854.N007_16535 1.8e-71 275.8 Alicyclobacillaceae macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,279A2@186823,4HBMF@91061,COG1136@1,COG1136@2 NA|NA|NA V Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides MAG.T12.39_02058 864069.MicloDRAFT_00045180 9.9e-100 370.5 Methylobacteriaceae salY ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1JZHH@119045,1PBKH@1224,2TW3U@28211,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T12.39_02059 1161401.ASJA01000005_gene2503 1.6e-134 486.5 Hyphomonadaceae oppA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1P91R@1224,2TT6P@28211,43X0B@69657,COG4166@1,COG4166@2 NA|NA|NA E COG4166 ABC-type oligopeptide transport system, periplasmic component MAG.T12.39_02060 298653.Franean1_4562 2.2e-73 282.3 Frankiales Bacteria 2GJU1@201174,4EUGB@85013,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T12.39_02061 190650.CC_0947 1.4e-100 372.9 Caulobacterales MA20_32365 Bacteria 1MVPQ@1224,2KG1I@204458,2TTJ4@28211,COG1024@1,COG1024@2 NA|NA|NA I PFAM Enoyl-CoA hydratase isomerase MAG.T12.39_02062 366602.Caul_2672 7.5e-52 209.9 Alphaproteobacteria Bacteria 1MWI7@1224,2U0S6@28211,COG5470@1,COG5470@2 NA|NA|NA S Domain of unknown function (DUF1330) MAG.T12.39_02063 366602.Caul_2671 1.3e-130 472.6 Caulobacterales dhmA 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 Bacteria 1MUSF@1224,2KI1E@204458,2TSK5@28211,COG0596@1,COG0596@2 NA|NA|NA S Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons MAG.T12.39_02064 450851.PHZ_c2249 5.3e-126 457.6 Caulobacterales 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1R64Z@1224,2KI60@204458,2U0BA@28211,COG1234@1,COG1234@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T12.39_02065 450851.PHZ_c2248 1.6e-135 489.2 Alphaproteobacteria Bacteria 1Q9ND@1224,2TT22@28211,COG0625@1,COG0625@2 NA|NA|NA O COG0625 Glutathione S-transferase MAG.T12.39_02066 69395.JQLZ01000002_gene1280 3.7e-49 201.4 Caulobacterales Bacteria 1N208@1224,2KHXC@204458,2UDE9@28211,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator MAG.T12.39_02067 1248917.ANFX01000029_gene2706 2.9e-37 162.5 Sphingomonadales Bacteria 1NXI4@1224,2KB99@204457,2UW4A@28211,COG4461@1,COG4461@2 NA|NA|NA G 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process MAG.T12.39_02068 876044.IMCC3088_2148 8.6e-97 360.9 Gammaproteobacteria zhuL 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1MW3Z@1224,1RYMQ@1236,COG0154@1,COG0154@2 NA|NA|NA J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases MAG.T12.39_02069 450851.PHZ_p0219 9.1e-194 683.7 Caulobacterales ko:K16090 ko00000,ko02000 1.B.14.1.11 Bacteria 1MV0X@1224,2KIB3@204458,2TVX5@28211,COG4774@1,COG4774@2 NA|NA|NA P Outer membrane protein beta-barrel family MAG.T12.39_02070 509190.Cseg_3450 5.5e-85 321.6 Caulobacterales pabB 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MVBJ@1224,2KG7S@204458,2TRWB@28211,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I domain protein MAG.T12.39_02071 190650.CC_2952 6.5e-47 194.5 Caulobacterales pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Bacteria 1MZAK@1224,2KJ74@204458,2U9QU@28211,COG0115@1,COG0115@2 NA|NA|NA EH Amino-transferase class IV MAG.T12.39_02072 450851.PHZ_c1714 4.6e-16 90.5 Bacteria Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding MAG.T12.39_02073 633149.Bresu_1557 1.2e-205 723.0 Caulobacterales deaD 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1MU49@1224,2KHJK@204458,2TST2@28211,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T12.39_02074 1379701.JPJC01000259_gene2981 3.6e-89 335.1 Sphingomonadales ko:K06955 ko00000 Bacteria 1R5C0@1224,2K1KZ@204457,2U3PZ@28211,COG3380@1,COG3380@2 NA|NA|NA S Flavin containing amine oxidoreductase MAG.T12.39_02075 58344.JOEL01000001_gene392 2e-81 309.3 Actinobacteria 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 R05320 RC01331 ko00000,ko00001,ko01000 Bacteria 2GNUC@201174,COG2175@1,COG2175@2 NA|NA|NA Q taurine catabolism dioxygenase MAG.T12.39_02076 1449049.JONW01000005_gene1381 1.2e-43 182.6 Bacteria Bacteria COG5649@1,COG5649@2 NA|NA|NA E Domain of unknown function (DU1801) MAG.T12.39_02077 1226994.AMZB01000099_gene1290 7.7e-116 423.7 Pseudomonas aeruginosa group yccK Bacteria 1MVEH@1224,1RPX5@1236,1YFHG@136841,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T12.39_02078 525904.Tter_2348 1e-44 187.2 Bacteria nicD GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248 3.5.1.106 ko:K15357,ko:K19311 ko00760,ko01120,map00760,map01120 M00622 R09126 RC00323,RC02431 ko00000,ko00001,ko00002,ko01000 Bacteria COG0596@1,COG0596@2 NA|NA|NA S hydrolase activity, acting on ester bonds MAG.T12.39_02079 448385.sce3476 4e-19 102.1 Myxococcales Bacteria 1Q9WU@1224,2B4W5@1,2WZ02@28221,2Z11D@29,31XNT@2,434NR@68525 NA|NA|NA MAG.T12.39_02080 190650.CC_0984 7.5e-239 833.2 Caulobacterales ggt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706 Bacteria 1MUV6@1224,2KI5R@204458,2TR49@28211,COG0405@1,COG0405@2 NA|NA|NA M Gamma-glutamyltranspeptidase MAG.T12.39_02081 1030157.AFMP01000008_gene3260 7.6e-127 460.7 Sphingomonadales gltT ko:K03309 ko00000 2.A.23 Bacteria 1MU0Q@1224,2K103@204457,2TRET@28211,COG1301@1,COG1301@2 NA|NA|NA C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family MAG.T12.39_02082 1292034.OR37_03470 0.0 1342.4 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MU9K@1224,2KHMI@204458,2TTUW@28211,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P TonB-dependent receptor MAG.T12.39_02083 1280946.HY29_13265 9.5e-76 290.4 Hyphomonadaceae VPA0331 Bacteria 1PHKW@1224,2V8GI@28211,43ZVX@69657,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain MAG.T12.39_02084 450851.PHZ_c2634 3.9e-25 120.2 Caulobacterales ko:K03704 ko00000,ko03000 Bacteria 1N6Q5@1224,2KH7U@204458,2UF6W@28211,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain MAG.T12.39_02086 509190.Cseg_1137 5.5e-11 73.9 Proteobacteria Bacteria 1NJ4B@1224,2EHCE@1,33B49@2 NA|NA|NA MAG.T12.39_02087 450851.PHZ_c3041 2.4e-35 154.5 Caulobacterales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1MZFU@1224,2KH0X@204458,2UBRU@28211,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T12.39_02088 1122970.AUHC01000021_gene2450 2.8e-34 151.0 Sphingomonadales ko:K07334 ko00000,ko02048 Bacteria 1MZ4I@1224,2K621@204457,2UD9W@28211,COG3549@1,COG3549@2 NA|NA|NA S RelE-like toxin of type II toxin-antitoxin system HigB MAG.T12.39_02089 1122970.AUHC01000021_gene2449 7.8e-35 152.9 Sphingomonadales ko:K21498 ko00000,ko02048 Bacteria 1N6H7@1224,2KCF1@204457,2UA4R@28211,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T12.39_02090 1121022.ABENE_19270 1e-16 92.8 Proteobacteria Bacteria 1NYFD@1224,2EQHV@1,33I3V@2 NA|NA|NA MAG.T12.39_02093 366602.Caul_3102 3.4e-238 831.2 Caulobacterales ptpA_1 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 1MWGR@1224,2KFZ6@204458,2TUXY@28211,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU peptidase MAG.T12.39_02094 450851.PHZ_c3328 7.5e-107 393.7 Caulobacterales echA21 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1PJ4R@1224,2KFK9@204458,2TSSU@28211,COG1024@1,COG1024@2 NA|NA|NA I PFAM Enoyl-CoA hydratase isomerase MAG.T12.39_02095 450851.PHZ_c1326 4.1e-238 830.5 Caulobacterales gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1MUKG@1224,2KG5G@204458,2TRHX@28211,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T12.39_02096 194867.ALBQ01000014_gene460 1.4e-10 72.4 Sphingomonadales Bacteria 1N74W@1224,2EK15@1,2K6RJ@204457,2UFQQ@28211,33DRN@2 NA|NA|NA MAG.T12.39_02097 450851.PHZ_c1324 1.3e-231 808.9 Caulobacterales gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1MUVQ@1224,2KF1R@204458,2TRFY@28211,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) MAG.T12.39_02098 450851.PHZ_c1323 8.2e-34 149.4 Caulobacterales gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1MZQP@1224,2KH1V@204458,2UBSZ@28211,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T12.39_02099 1000565.METUNv1_02302 9.5e-58 231.1 Rhodocyclales Bacteria 1NDBI@1224,2KUDC@206389,2VJ4P@28216,COG3174@1,COG3174@2 NA|NA|NA S Domain of unknown function (DUF4010) MAG.T12.39_02100 670292.JH26_05400 2.9e-79 302.0 Methylobacteriaceae spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1JRAU@119045,1QQ53@1224,2TVH5@28211,COG0566@1,COG0566@2 NA|NA|NA J tRNA rRNA methyltransferase (SpoU) MAG.T12.39_02101 1292034.OR37_02142 8.1e-189 666.8 Caulobacterales Bacteria 1NU31@1224,2KF62@204458,2U5M0@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_02102 1242864.D187_004518 2.5e-82 312.4 Proteobacteria Bacteria 1MX47@1224,COG4638@1,COG4638@2 NA|NA|NA P rieske 2Fe-2S domain protein MAG.T12.39_02103 450851.PHZ_c1019 1.3e-214 752.3 Caulobacterales purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095,iSB619.SA_RS09895 Bacteria 1MV4B@1224,2KG5B@204458,2TQUE@28211,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily MAG.T12.39_02104 450851.PHZ_c1017 3.4e-36 157.5 Caulobacterales MA20_09035 Bacteria 1MZRN@1224,2KGZG@204458,2UC1G@28211,COG5467@1,COG5467@2 NA|NA|NA S Domain of unknown function (DUF1476) MAG.T12.39_02106 450851.PHZ_c1254 1.2e-20 104.8 Caulobacterales rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1MU75@1224,2KFH6@204458,2TSI0@28211,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T12.39_02107 450851.PHZ_c1255 7.2e-63 246.5 Caulobacterales rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RCWN@1224,2KGBZ@204458,2U749@28211,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 MAG.T12.39_02108 450851.PHZ_c1256 4.4e-124 451.4 Caulobacterales enpP 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1N5SF@1224,2KG77@204458,2TU7V@28211,COG1524@1,COG1524@2 NA|NA|NA S PFAM type I phosphodiesterase nucleotide pyrophosphatase MAG.T12.39_02109 450851.PHZ_c1260 2.2e-134 485.7 Caulobacterales tetA ko:K08151,ko:K08153 M00668,M00717 ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8 Bacteria 1MVSH@1224,2KFDV@204458,2TUEW@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T12.39_02110 450851.PHZ_c1261 9.1e-166 590.1 Caulobacterales degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0051716,GO:0051788,GO:0061077,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2KG2P@204458,2TS6B@28211,COG0265@1,COG0265@2 NA|NA|NA M Belongs to the peptidase S1C family MAG.T12.39_02111 450851.PHZ_c1262 5.2e-192 677.2 Caulobacterales rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 ko:K07478 ko00000 Bacteria 1MUVS@1224,2KFPV@204458,2TQVF@28211,COG2256@1,COG2256@2 NA|NA|NA L AAA ATPase central domain protein MAG.T12.39_02112 1179778.PMM47T1_14186 4.8e-33 147.9 Bacteria pseH 2.3.1.202 ko:K15896 ko00520,map00520 R09842 RC00004,RC00166 ko00000,ko00001,ko01000 Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins MAG.T12.39_02113 450851.PHZ_c1264 1.3e-89 336.3 Caulobacterales 2.1.1.191,5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 ko:K06177,ko:K06179,ko:K06180,ko:K06969 ko00000,ko01000,ko03009,ko03016 Bacteria 1MVDX@1224,2KFD0@204458,2U3E8@28211,COG0564@1,COG0564@2 NA|NA|NA J pseudouridine synthase MAG.T12.39_02114 366602.Caul_1657 8.7e-31 139.8 Caulobacterales crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1MZNH@1224,2KH2X@204458,2UBUP@28211,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity MAG.T12.39_02115 450851.PHZ_c1267 1.5e-138 499.2 Caulobacterales rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.191,5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 ko:K06177,ko:K06179,ko:K06180,ko:K06969 ko00000,ko01000,ko03009,ko03016 Bacteria 1MVDX@1224,2KFRU@204458,2TTQC@28211,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T12.39_02116 450851.PHZ_c1268 4.6e-76 291.2 Caulobacterales Bacteria 1Q3B5@1224,2KGJT@204458,2TVK1@28211,COG5387@1,COG5387@2 NA|NA|NA O ATP12 chaperone protein MAG.T12.39_02117 450851.PHZ_c1274 5.1e-263 913.3 Caulobacterales pccB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3,6.4.1.4 ko:K01966,ko:K01969 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00036,M00373,M00741 R01859,R04138 RC00097,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVAX@1224,2KF45@204458,2TRI1@28211,COG4799@1,COG4799@2 NA|NA|NA I PFAM carboxyl transferase MAG.T12.39_02118 452662.SJA_C1-26050 1.7e-23 115.9 Sphingomonadales Bacteria 1N7MV@1224,2KDAI@204457,2UMMN@28211,32YV7@2,COG1226@1 NA|NA|NA P Ion channel MAG.T12.39_02119 450851.PHZ_c1277 1.8e-73 282.0 Caulobacterales msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 1RGWC@1224,2KGJ3@204458,2U5Q0@28211,COG0229@1,COG0229@2 NA|NA|NA C Belongs to the MsrB Met sulfoxide reductase family MAG.T12.39_02120 450851.PHZ_c1278 1.3e-290 1005.4 Caulobacterales pccA 6.4.1.3 ko:K01965 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 1P6RE@1224,2KFWF@204458,2TRC2@28211,COG4770@1,COG4770@2 NA|NA|NA I Carbamoyl-phosphate synthase L chain MAG.T12.39_02121 450851.PHZ_c3170 1.6e-72 279.3 Caulobacterales MA20_05290 Bacteria 1RDKW@1224,2KIT2@204458,2TQP3@28211,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T12.39_02122 450851.PHZ_c1831 1.7e-219 768.5 Caulobacterales metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 1NQME@1224,2KFZJ@204458,2TQW9@28211,COG2873@1,COG2873@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T12.39_02124 69395.JQLZ01000001_gene2899 4.2e-10 70.9 Caulobacterales 2.7.13.3 ko:K07647 ko02020,map02020 M00455 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1N1XD@1224,2KGYM@204458,2UE9N@28211,COG2198@1,COG2198@2 NA|NA|NA T Hpt domain MAG.T12.39_02125 450851.PHZ_c2045 4.5e-153 547.4 Caulobacterales ko:K03566 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1MWY0@1224,2KG6K@204458,2TSD9@28211,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family MAG.T12.39_02126 450851.PHZ_c2044 6.3e-90 337.4 Caulobacterales cysG 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 ko:K02302,ko:K02303,ko:K02304,ko:K03795,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947,R05807 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUI0@1224,2KG1D@204458,2TRJC@28211,COG0007@1,COG0007@2 NA|NA|NA H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme MAG.T12.39_02127 450851.PHZ_c2043 1.3e-36 159.1 Caulobacterales Bacteria 1PU0X@1224,2EG12@1,2KH3V@204458,2V5TQ@28211,32XZ7@2 NA|NA|NA S Protein of unknown function (DUF2849) MAG.T12.39_02128 509190.Cseg_1246 5e-240 837.0 Caulobacterales cysI 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 ko:K00362,ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00530,M00531 R00787,R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVVB@1224,2KG66@204458,2TRCR@28211,COG0155@1,COG0155@2 NA|NA|NA C Sulfite reductase MAG.T12.39_02129 366602.Caul_3266 7.1e-44 183.7 Caulobacterales 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 Bacteria 1RJR9@1224,2KH1T@204458,2UDH7@28211,COG3749@1,COG3749@2 NA|NA|NA S Bacterial protein of unknown function (DUF934) MAG.T12.39_02130 69395.JQLZ01000001_gene2887 2.4e-99 368.6 Caulobacterales cysH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2392 Bacteria 1MXUR@1224,2KGB2@204458,2U5AP@28211,COG0175@1,COG0175@2 NA|NA|NA EH Belongs to the PAPS reductase family. CysH subfamily MAG.T12.39_02131 450851.PHZ_c2039 9.5e-120 436.4 Caulobacterales fpr 1.18.1.2,1.19.1.1 ko:K00528,ko:K02823 ko00240,ko01100,map00240,map01100 R10159 ko00000,ko00001,ko01000 Bacteria 1QTSK@1224,2KF4M@204458,2TQNB@28211,COG0543@1,COG0543@2 NA|NA|NA CH Oxidoreductase NAD-binding domain MAG.T12.39_02132 1449049.JONW01000012_gene301 2.1e-53 215.3 Caulobacterales Bacteria 1N6H6@1224,2KIZX@204458,2UDCU@28211,COG3584@1,COG3584@2 NA|NA|NA S 3D domain MAG.T12.39_02133 450851.PHZ_c2036 3.1e-67 261.5 Caulobacterales gst5 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1REDI@1224,2KGE3@204458,2TUGP@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain MAG.T12.39_02134 450851.PHZ_c2035 3.3e-93 348.6 Caulobacterales Bacteria 1R38K@1224,28MR2@1,2KFYY@204458,2TZZC@28211,2ZAZS@2 NA|NA|NA MAG.T12.39_02135 450851.PHZ_c2034 4.2e-33 147.9 Caulobacterales 3.6.1.55 ko:K03574,ko:K12152 ko00000,ko01000,ko03400 Bacteria 1N59Z@1224,2KH19@204458,2UE59@28211,COG1051@1,COG1051@2 NA|NA|NA F Belongs to the Nudix hydrolase family MAG.T12.39_02136 450851.PHZ_c2033 1.9e-121 442.2 Caulobacterales folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWU4@1224,2KFUC@204458,2TRZZ@28211,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate MAG.T12.39_02137 69395.JQLZ01000002_gene1339 2.2e-26 125.9 Caulobacterales MA20_38065 ko:K02067,ko:K09857,ko:K18480 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27,3.A.1.27.1 Bacteria 1N4DJ@1224,2KGXV@204458,2UCPR@28211,COG3218@1,COG3218@2 NA|NA|NA S ABC-type transport auxiliary lipoprotein component MAG.T12.39_02138 190650.CC_2320 1.6e-78 299.7 Caulobacterales MA20_08125 ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MU4B@1224,2KFWG@204458,2U1JN@28211,COG1463@1,COG1463@2 NA|NA|NA Q PFAM Mammalian cell entry related domain protein MAG.T12.39_02139 450851.PHZ_c2029 2.2e-100 372.1 Caulobacterales iamA ko:K02065,ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MUSD@1224,2KF7N@204458,2TR2I@28211,COG1127@1,COG1127@2 NA|NA|NA Q ABC transporter MAG.T12.39_02140 1292034.OR37_01481 3.1e-100 372.1 Caulobacterales mlaE_1 ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MVPN@1224,2KF9C@204458,2TSGS@28211,COG0767@1,COG0767@2 NA|NA|NA Q Permease MlaE MAG.T12.39_02141 59538.XP_005978144.1 1.3e-112 412.9 Bilateria Metazoa 38FUK@33154,3CNJ9@33208,3E4QF@33213,COG3491@1,KOG0143@2759 NA|NA|NA Q non-haem dioxygenase in morphine synthesis N-terminal MAG.T12.39_02142 391600.ABRU01000011_gene3317 5.5e-73 281.2 Caulobacterales rbsK GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0046835,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MV5B@1224,2KH4I@204458,2TSUM@28211,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway MAG.T12.39_02143 983920.Y88_2864 8.3e-83 313.9 Sphingomonadales rihA GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1MUIW@1224,2KBDZ@204457,2TSXQ@28211,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase MAG.T12.39_02144 366602.Caul_2674 1.3e-232 812.4 Caulobacterales 3.1.6.12 ko:K01135,ko:K01138 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUJH@1224,2KID7@204458,2TSB8@28211,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T12.39_02145 366602.Caul_2676 2.5e-86 325.1 Caulobacterales MA20_23730 Bacteria 1MV6E@1224,2KGU2@204458,2TVJ4@28211,COG3917@1,COG3917@2 NA|NA|NA Q DSBA-like thioredoxin domain MAG.T12.39_02147 509190.Cseg_2608 8.5e-139 500.0 Caulobacterales MA20_32430 Bacteria 1MVMI@1224,2KH4K@204458,2TTZY@28211,COG1305@1,COG1305@2 NA|NA|NA E transglutaminase MAG.T12.39_02148 1292034.OR37_02676 5.4e-106 391.0 Caulobacterales MA20_32425 Bacteria 1MVZK@1224,2KGYF@204458,2TQUM@28211,COG2307@1,COG2307@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. MAG.T12.39_02149 190650.CC_1602 1.8e-233 815.1 Caulobacterales gcs2 Bacteria 1MUAD@1224,2KG7P@204458,2TRI7@28211,COG2308@1,COG2308@2 NA|NA|NA S Circularly permuted ATP-grasp type 2 MAG.T12.39_02150 366602.Caul_2199 1.3e-156 560.1 Caulobacterales tamA ko:K07278 ko00000,ko02000 1.B.33.2.4 Bacteria 1MUKM@1224,2KFZH@204458,2TRWD@28211,COG0729@1,COG0729@2 NA|NA|NA M PFAM surface antigen MAG.T12.39_02151 450851.PHZ_c1408 0.0 1103.2 Caulobacterales tamB ko:K09800 ko00000,ko02000 Bacteria 1MUVD@1224,2KFIH@204458,2TR45@28211,COG2911@1,COG2911@2 NA|NA|NA S TamB, inner membrane protein subunit of TAM complex MAG.T12.39_02152 450851.PHZ_c1410 4.4e-43 180.6 Caulobacterales hspQ ko:K11940 ko00000,ko03036 Bacteria 1RHM7@1224,2KGVA@204458,2U9MS@28211,COG3785@1,COG3785@2 NA|NA|NA S DNA-binding protein MAG.T12.39_02153 450851.PHZ_c1411 2.6e-128 465.3 Caulobacterales ppx GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1MV35@1224,2KEZX@204458,2TT2C@28211,COG0248@1,COG0248@2 NA|NA|NA FP Ppx GppA phosphatase MAG.T12.39_02154 450851.PHZ_c1412 3.5e-97 361.3 Caulobacterales ftsJ 2.1.1.166 ko:K02427 ko00000,ko01000,ko03009 Bacteria 1MW1C@1224,2KF92@204458,2TSBW@28211,COG0293@1,COG0293@2 NA|NA|NA J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit MAG.T12.39_02155 450851.PHZ_c1415 2.2e-223 781.6 Caulobacterales guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1MUJM@1224,2KFCD@204458,2TQXC@28211,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth MAG.T12.39_02156 1292034.OR37_02660 2.9e-29 134.8 Caulobacterales Bacteria 1N00R@1224,2KH7S@204458,2U94Y@28211,COG3686@1,COG3686@2 NA|NA|NA S MAPEG family MAG.T12.39_02157 450851.PHZ_c1416 4.3e-154 551.2 Caulobacterales sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1MV2Q@1224,2KG4F@204458,2TS6U@28211,COG0144@1,COG0144@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family MAG.T12.39_02158 450851.PHZ_c1417 3.3e-262 910.6 Caulobacterales guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 1MU2A@1224,2KFWX@204458,2TRN0@28211,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP MAG.T12.39_02159 1282876.BAOK01000002_gene496 3.1e-243 847.8 Alphaproteobacteria MA20_26775 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 ko:K03379,ko:K18091 ko00930,ko01120,ko01130,ko01220,map00930,map01120,map01130,map01220 M00819 R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko00002,ko01000 Bacteria 1NSY9@1224,2TUSD@28211,COG2072@1,COG2072@2 NA|NA|NA P Flavoprotein involved in K transport MAG.T12.39_02160 1205680.CAKO01000038_gene1961 4.4e-45 188.3 Rhodospirillales 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 R03026 RC00831 ko00000,ko00001,ko01000 Bacteria 1RG4N@1224,2JWTN@204441,2U8TJ@28211,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_02161 1121949.AQXT01000002_gene2028 3e-103 381.7 Alphaproteobacteria Bacteria 1QTUD@1224,2TW51@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_02162 450851.PHZ_c2511 2.5e-103 382.5 Caulobacterales Bacteria 1R7F8@1224,2KI2V@204458,2U0DG@28211,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T12.39_02163 1382303.JPOM01000001_gene1759 2.7e-102 379.0 Caulobacterales hadA 2.8.3.17,2.8.3.24 ko:K13607,ko:K20882 ko00960,map00960 R07796,R11462 RC00014,RC00131,RC00137 ko00000,ko00001,ko01000 Bacteria 1MWPB@1224,2KFDM@204458,2U1YE@28211,COG1804@1,COG1804@2 NA|NA|NA C CoA-transferase family III MAG.T12.39_02164 1429916.X566_16725 9.7e-190 669.5 Bradyrhizobiaceae MA20_05130 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5G@1224,2TQQ7@28211,3JR1V@41294,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T12.39_02165 450851.PHZ_c3128 3.7e-125 454.9 Alphaproteobacteria qor_1 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MW2V@1224,2U07M@28211,COG0604@1,COG0604@2 NA|NA|NA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases MAG.T12.39_02166 1429916.X566_10260 2.7e-57 228.8 Proteobacteria paaG 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 Bacteria 1NZ0X@1224,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_02167 1234595.C725_1869 2.9e-74 286.2 Alphaproteobacteria ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2TVI8@28211,COG2211@1,COG2211@2 NA|NA|NA G COG2211 Na melibiose symporter and related transporters MAG.T12.39_02168 450851.PHZ_c1979 1.7e-290 1005.4 Alphaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1RBA9@1224,2U0CH@28211,COG1629@1,COG4771@2 NA|NA|NA P COG1629 Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_02169 450851.PHZ_c3207 6.3e-134 483.8 Caulobacterales qor 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MX8A@1224,2KFJF@204458,2TR1J@28211,COG0604@1,COG0604@2 NA|NA|NA C NAD(P)H quinone oxidoreductase, PIG3 family MAG.T12.39_02170 450851.PHZ_c3206 1.9e-11 74.7 Caulobacterales Bacteria 1NG8P@1224,2KHEN@204458,2UJB2@28211,COG5509@1,COG5509@2 NA|NA|NA S Protein of unknown function (DUF1192) MAG.T12.39_02171 1035191.HMPREF0185_02942 1.4e-36 159.5 Caulobacterales MA20_18080 ko:K13592 ko04112,map04112 ko00000,ko00001 Bacteria 1RJIA@1224,2KGF5@204458,2U9ID@28211,COG5317@1,COG5317@2 NA|NA|NA S Regulator of CtrA degradation MAG.T12.39_02172 450851.PHZ_c3204 2.7e-32 144.1 Caulobacterales rpmE GO:0008150,GO:0040007 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ69@1224,2KH15@204458,2UBSC@28211,COG0254@1,COG0254@2 NA|NA|NA J Binds the 23S rRNA MAG.T12.39_02173 450851.PHZ_c3203 1.4e-222 779.2 Caulobacterales msbA ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1MUBM@1224,2KFS9@204458,2TQMR@28211,COG1132@1,COG1132@2 NA|NA|NA V TIGRFAM lipid A ABC exporter family, fused ATPase and inner membrane subunits MAG.T12.39_02174 450851.PHZ_c3202 6.3e-113 414.1 Caulobacterales glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1MVWZ@1224,2KF5K@204458,2TV4M@28211,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase MAG.T12.39_02175 450851.PHZ_c3201 3.3e-125 454.5 Caulobacterales suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUQT@1224,2KFMJ@204458,2TR06@28211,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase MAG.T12.39_02176 1449049.JONW01000002_gene2465 5.5e-81 307.4 Caulobacterales thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV42@1224,2KG97@204458,2TSSA@28211,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) MAG.T12.39_02177 983920.Y88_2399 2.3e-20 105.5 Sphingomonadales Bacteria 1RDSK@1224,2K7H5@204457,2U80Y@28211,COG3161@1,COG3161@2 NA|NA|NA H chorismate lyase activity MAG.T12.39_02178 391600.ABRU01000050_gene206 1.2e-165 590.1 Caulobacterales opgH GO:0003674,GO:0003824,GO:0005575,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0044238,GO:0071704,GO:1901576 ko:K03669 ko00000,ko01000,ko01003,ko02000 4.D.3.1.1 GT2 Bacteria 1MVXZ@1224,2KI3Q@204458,2TQU8@28211,COG2943@1,COG2943@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T12.39_02179 1229204.AMYY01000010_gene560 6.7e-60 237.3 Alphaproteobacteria Bacteria 1R4CU@1224,2U2AF@28211,COG1835@1,COG1835@2,COG3371@1,COG3371@2 NA|NA|NA I Acyltransferase family MAG.T12.39_02180 633149.Bresu_2313 6.8e-116 424.1 Caulobacterales Bacteria 1R4CU@1224,2KGG5@204458,2U2AF@28211,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T12.39_02181 570967.JMLV01000012_gene3147 1.7e-57 229.2 Rhodospirillales Bacteria 1RF02@1224,2JRWN@204441,2U69V@28211,COG0247@1,COG0247@2 NA|NA|NA C Protein of unknown function (DUF3501) MAG.T12.39_02182 107636.JQNK01000008_gene4236 1.2e-138 500.0 Methylocystaceae glpC GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 1MWTK@1224,2U059@28211,36YWF@31993,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain MAG.T12.39_02183 1333998.M2A_0325 2e-65 255.0 unclassified Alphaproteobacteria rbr Bacteria 1R9WG@1224,2U5EA@28211,4BRY6@82117,COG1592@1,COG1592@2 NA|NA|NA C Rubrerythrin MAG.T12.39_02184 252305.OB2597_06875 8.1e-68 263.8 Oceanicola MA20_40050 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW8Z@1224,2PF1F@252301,2TS64@28211,COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity MAG.T12.39_02185 745310.G432_06425 1.5e-174 620.2 Sphingomonadales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MXFM@1224,2K14T@204457,2TWYV@28211,COG4206@1,COG4206@2 NA|NA|NA H Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_02186 1282876.BAOK01000001_gene1781 1.6e-25 122.5 Alphaproteobacteria Bacteria 1NDQE@1224,2E474@1,2VFXZ@28211,32Z30@2 NA|NA|NA MAG.T12.39_02187 1038858.AXBA01000003_gene4116 5.8e-40 171.4 Xanthobacteraceae besA ko:K07017 ko00000 Bacteria 1RB1X@1224,2TUQ2@28211,3EZ3W@335928,COG2819@1,COG2819@2 NA|NA|NA S Putative esterase MAG.T12.39_02188 402881.Plav_0752 4.5e-119 434.5 Rhodobiaceae adhT ko:K19745 ko00640,ko01100,map00640,map01100 R00919 RC00095 ko00000,ko00001,ko01000 Bacteria 1JNJV@119043,1MV3W@1224,2TRW7@28211,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T12.39_02189 324925.Ppha_0671 1.2e-08 68.2 Chlorobi Bacteria 1FFHR@1090,COG3074@1,COG3074@2 NA|NA|NA D FtsZ-dependent cytokinesis MAG.T12.39_02190 1123240.ATVO01000004_gene971 1.3e-22 112.8 Proteobacteria VPA1252 Bacteria 1NGUY@1224,2DR7N@1,33AJV@2 NA|NA|NA S Protein of unknown function (DUF3429) MAG.T12.39_02191 46429.BV95_00492 1.1e-45 189.1 Sphingomonadales ko:K09922 ko00000 Bacteria 1N51Z@1224,2K56Z@204457,2UBU7@28211,COG3169@1,COG3169@2 NA|NA|NA S Putative member of DMT superfamily (DUF486) MAG.T12.39_02192 402881.Plav_2013 6.1e-106 391.0 Alphaproteobacteria Bacteria 1R696@1224,2U201@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain MAG.T12.39_02193 1280954.HPO_05422 6.1e-167 594.3 Hyphomonadaceae 3.1.6.1 ko:K01130,ko:K01138 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,2TTXG@28211,43WDJ@69657,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes MAG.T12.39_02194 450851.PHZ_c1979 4.3e-148 532.3 Alphaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1RBA9@1224,2U0CH@28211,COG1629@1,COG4771@2 NA|NA|NA P COG1629 Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_02195 1205680.CAKO01000010_gene3872 2.4e-209 734.9 Alphaproteobacteria MA20_23085 ko:K10215 ko00627,ko01120,map00627,map01120 R07836,R07837 RC02100,RC03121 ko00000,ko00001,ko01000 Bacteria 1MU71@1224,2TV2E@28211,COG2072@1,COG2072@2 NA|NA|NA P Flavoprotein involved in K transport MAG.T12.39_02196 317655.Sala_1615 6.7e-66 257.7 Sphingomonadales ko:K09973 ko00000 Bacteria 1MVCW@1224,2JZWN@204457,2U5RA@28211,COG3735@1,COG3735@2 NA|NA|NA S protein conserved in bacteria MAG.T12.39_02198 1090319.KE386571_gene587 1.6e-20 104.8 Sphingomonadales ko:K07729 ko00000,ko03000 Bacteria 1N6SS@1224,2K6RT@204457,2UFFG@28211,COG1476@1,COG1476@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_02199 450851.PHZ_c2617 9.5e-124 449.9 Alphaproteobacteria Bacteria 1QU7K@1224,2TW27@28211,COG2267@1,COG2267@2 NA|NA|NA I Alpha beta hydrolase MAG.T12.39_02200 450851.PHZ_c3011 4.1e-159 567.8 Caulobacterales Bacteria 1QUPB@1224,2KHMS@204458,2TTFV@28211,COG3420@1,COG3420@2 NA|NA|NA P Periplasmic copper-binding protein (NosD) MAG.T12.39_02201 450851.PHZ_c3012 2.4e-118 432.2 Alphaproteobacteria Bacteria 1QUPA@1224,2U3YK@28211,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T12.39_02202 158500.BV97_03927 1.4e-189 669.5 Sphingomonadales ybaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03455 ko00000 2.A.37 Bacteria 1MV34@1224,2K12V@204457,2TRC5@28211,COG1226@1,COG1226@2,COG4651@1,COG4651@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T12.39_02203 1123240.ATVO01000003_gene549 2e-176 625.5 Sphingomonadales ko:K03307 ko00000 2.A.21 Bacteria 1MXWV@1224,2KDAS@204457,2U1ED@28211,COG4146@1,COG4146@2 NA|NA|NA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T12.39_02204 1395516.PMO01_10980 1e-19 103.2 Gammaproteobacteria Bacteria 1NDZG@1224,1SJ7H@1236,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T12.39_02205 450851.PHZ_c0489 6.8e-113 414.5 Caulobacterales ko:K02022,ko:K12537,ko:K16300 M00328,M00571 ko00000,ko00002,ko02000,ko02044 8.A.1,8.A.1.3.3 Bacteria 1MUI8@1224,2KH9Q@204458,2TSP0@28211,COG0845@1,COG0845@2 NA|NA|NA M TIGRFAM type I secretion membrane fusion protein, HlyD family MAG.T12.39_02206 450851.PHZ_c0488 7.9e-188 663.7 Caulobacterales aprD ko:K06147,ko:K06148,ko:K12536,ko:K16299 ko02010,map02010 M00328,M00571 ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.110.10,3.A.1.21 Bacteria 1NTI5@1224,2KI2A@204458,2TR17@28211,COG4618@1,COG4618@2 NA|NA|NA V ABC transporter transmembrane region MAG.T12.39_02207 888439.HMPREF9240_00534 4.4e-16 92.0 Actinobacteria Bacteria 2E01T@1,2IIWX@201174,32VQY@2,4D4GS@85005 NA|NA|NA MAG.T12.39_02208 450851.PHZ_c0486 1.7e-07 63.9 Caulobacterales ko:K20541 ko00000,ko02000 4.D.3.1.6 Bacteria 1R0EJ@1224,2KJW5@204458,2TYPZ@28211,COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T12.39_02209 450851.PHZ_c0485 8.3e-161 573.2 Caulobacterales cps1D Bacteria 1N02S@1224,2KI6Y@204458,2U241@28211,COG1442@1,COG1442@2 NA|NA|NA M glycosyl transferase family 8 MAG.T12.39_02210 450851.PHZ_c0484 7.4e-46 190.7 Caulobacterales ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1PAJ3@1224,2KHWS@204458,2U2P6@28211,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T12.39_02211 450851.PHZ_c0482 5.2e-84 318.2 Caulobacterales ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1RB2G@1224,2KIPK@204458,2U7MV@28211,COG3551@1,COG3551@2 NA|NA|NA S Protein conserved in bacteria MAG.T12.39_02213 190650.CC_2891 1.2e-52 213.4 Alphaproteobacteria Bacteria 1QTWG@1224,2TX57@28211,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T12.39_02214 450851.PHZ_c0185 6e-113 414.1 Caulobacterales yfdH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1MWE5@1224,2KGCH@204458,2TRRT@28211,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T12.39_02215 1229205.BUPH_05545 1.3e-15 91.3 Burkholderiaceae Bacteria 1KAWW@119060,1N5XI@1224,2B90Y@1,2VZG0@28216,322BP@2 NA|NA|NA MAG.T12.39_02217 450851.PHZ_c0478 4.3e-91 341.3 Caulobacterales rfbD ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 1MWG4@1224,2KHDA@204458,2TVJK@28211,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter MAG.T12.39_02218 450851.PHZ_c0477 1.1e-99 369.8 Caulobacterales rfbE 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 1MWWC@1224,2KGIR@204458,2TU3M@28211,COG1134@1,COG1134@2 NA|NA|NA GM ABC transporter MAG.T12.39_02219 450851.PHZ_c0484 5e-107 395.2 Caulobacterales ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1PAJ3@1224,2KHWS@204458,2U2P6@28211,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T12.39_02220 426117.M446_0315 1e-159 570.5 Methylobacteriaceae ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1JS9T@119045,1MX5Z@1224,2U0IP@28211,COG1215@1,COG1215@2,COG1216@1,COG1216@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T12.39_02221 1005048.CFU_2660 5.4e-93 348.2 Oxalobacteraceae 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 1MUSU@1224,2WA04@28216,47500@75682,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T12.39_02222 450851.PHZ_c3285 9.5e-60 236.9 Caulobacterales cOQ9 ko:K18587 ko00000 Bacteria 1MW25@1224,2KGI4@204458,2U9ST@28211,COG5590@1,COG5590@2 NA|NA|NA S rpsU-divergently transcribed protein MAG.T12.39_02223 366602.Caul_0900 2.2e-30 137.9 Caulobacterales rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZA1@1224,2KHD5@204458,2UC58@28211,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family MAG.T12.39_02224 450851.PHZ_c3283 3.2e-283 980.7 Caulobacterales ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU6J@1224,2KFGW@204458,2TSYQ@28211,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins MAG.T12.39_02225 1292034.OR37_00878 4.7e-87 327.8 Caulobacterales folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_3924,iPC815.YPO3501 Bacteria 1MUIR@1224,2KF7T@204458,2TTMG@28211,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives MAG.T12.39_02226 66377.JOBH01000007_gene2187 8e-92 343.6 Actinobacteria MA20_32450 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJWX@201174,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T12.39_02227 1292034.OR37_00877 6e-106 390.6 Caulobacterales thiD 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9J@1224,2KF47@204458,2TUKR@28211,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase MAG.T12.39_02228 450851.PHZ_c3280 7.7e-68 263.5 Caulobacterales ko:K09962 ko00000 Bacteria 1R5GH@1224,2KGN2@204458,2U1BS@28211,COG3575@1,COG3575@2 NA|NA|NA S Nucleotidyltransferase MAG.T12.39_02229 450851.PHZ_c3276 3.3e-158 565.5 Alphaproteobacteria 2.7.13.3 ko:K20974 ko02020,ko02025,map02020,map02025 M00820 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1NC9X@1224,2TWW1@28211,COG0784@1,COG0784@2,COG5000@1,COG5000@2,COG5002@1,COG5002@2 NA|NA|NA T cheY-homologous receiver domain MAG.T12.39_02230 1292034.OR37_02377 5.7e-18 97.1 Caulobacterales Bacteria 1NN1Z@1224,2EUF7@1,2KHFB@204458,2UKHY@28211,33MXH@2 NA|NA|NA MAG.T12.39_02231 509190.Cseg_0703 7.5e-07 60.5 Caulobacterales Bacteria 1P5IU@1224,29A1H@1,2KJDA@204458,2UYAN@28211,2ZX2Z@2 NA|NA|NA MAG.T12.39_02232 450851.PHZ_c3273 9.6e-182 642.9 Caulobacterales serC 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MUB5@1224,2KF0M@204458,2TSHT@28211,COG1932@1,COG1932@2 NA|NA|NA EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine MAG.T12.39_02233 450851.PHZ_c3272 5.8e-246 856.7 Caulobacterales serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5Z@1224,2KG2A@204458,2TR0F@28211,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase MAG.T12.39_02235 450851.PHZ_c3266 2.4e-67 262.3 Caulobacterales GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K14160 ko00000,ko03400 Bacteria 1MY56@1224,2KGWK@204458,2TT91@28211,COG4544@1,COG4544@2 NA|NA|NA S SOS response MAG.T12.39_02236 450851.PHZ_c3267 5.8e-152 544.3 Caulobacterales 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1MU5X@1224,2KFTX@204458,2TQVR@28211,COG0389@1,COG0389@2 NA|NA|NA L Nucleotidyltransferase DNA polymerase involved in DNA repair MAG.T12.39_02237 450851.PHZ_c3268 0.0 1437.2 Caulobacterales dnaE2 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MUE4@1224,2KF9I@204458,2TRUB@28211,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase MAG.T12.39_02238 1110502.TMO_2173 7.5e-35 154.1 Alphaproteobacteria Bacteria 1N6VK@1224,2UACE@28211,333S7@2,arCOG08992@1 NA|NA|NA MAG.T12.39_02239 450851.PHZ_c3263 1e-170 606.7 Caulobacterales pnbA ko:K03929 ko00000,ko01000 CE10 Bacteria 1MVQZ@1224,2KHMF@204458,2TUA9@28211,COG2272@1,COG2272@2 NA|NA|NA M Carboxylesterase family MAG.T12.39_02240 450851.PHZ_c3254 9.3e-195 686.4 Caulobacterales pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1MU21@1224,2KEXG@204458,2TRFV@28211,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family MAG.T12.39_02241 450851.PHZ_c3251 1.1e-109 403.3 Caulobacterales glk 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFI@1224,2KGB6@204458,2U0CA@28211,COG0837@1,COG0837@2 NA|NA|NA F Belongs to the bacterial glucokinase family MAG.T12.39_02242 450851.PHZ_c3249 9.3e-96 356.7 Caulobacterales MA20_40055 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 Bacteria 1MWGT@1224,2KIJZ@204458,2TV7F@28211,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T12.39_02243 1280944.HY17_08405 2.9e-178 631.3 Alphaproteobacteria 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUDR@1224,2TQKE@28211,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T12.39_02244 450851.PHZ_c3247 2.3e-178 631.7 Caulobacterales Bacteria 1MVY1@1224,2KGW6@204458,2TVJ9@28211,COG1804@1,COG1804@2 NA|NA|NA C CoA-transferase family III MAG.T12.39_02245 1217720.ALOX01000006_gene1651 8.9e-45 186.8 Proteobacteria adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1N0HQ@1224,COG0563@1,COG0563@2 NA|NA|NA F COG0563 Adenylate kinase and related kinases MAG.T12.39_02248 1282362.AEAC466_06240 1.2e-30 141.0 Caulobacterales 3.4.21.116 ko:K06399 ko00000,ko01000,ko01002 Bacteria 1N5HU@1224,2KHIH@204458,2UDKE@28211,COG0793@1,COG0793@2 NA|NA|NA M Aspartyl protease MAG.T12.39_02251 1177181.T9A_00913 8e-28 129.8 Gammaproteobacteria Bacteria 1N4F0@1224,1T69J@1236,2DRRT@1,32URI@2 NA|NA|NA MAG.T12.39_02252 190650.CC_2961 5.7e-30 137.1 Bacteria 3.3.2.8 ko:K10533 ko00903,map00903 R05784,R09387 RC01473,RC02519 ko00000,ko00001,ko01000 Bacteria COG4308@1,COG4308@2 NA|NA|NA Q Limonene-1,2-epoxide hydrolase catalytic domain MAG.T12.39_02253 509190.Cseg_3253 4.1e-31 141.0 Caulobacterales Bacteria 1MZDD@1224,2KH62@204458,2UCM4@28211,COG5349@1,COG5349@2 NA|NA|NA S Protein of unknown function (DUF983) MAG.T12.39_02254 450851.PHZ_c2988 6.7e-163 580.5 Caulobacterales kgtP ko:K03761,ko:K03762 ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 Bacteria 1MVZG@1224,2KFK8@204458,2TRS1@28211,COG0477@1,COG0477@2 NA|NA|NA EGP transporter MAG.T12.39_02255 69395.JQLZ01000001_gene2979 1.7e-30 138.7 Caulobacterales Bacteria 1RHEZ@1224,2KH5B@204458,2U97K@28211,COG2315@1,COG2315@2 NA|NA|NA S YjbR MAG.T12.39_02256 1125973.JNLC01000010_gene1615 2.1e-85 322.0 Bradyrhizobiaceae msrA 1.8.4.11 ko:K07304 ko00000,ko01000 Bacteria 1MVUS@1224,2TSAM@28211,3JV0Z@41294,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T12.39_02258 1333998.M2A_0706 5.4e-85 321.2 Alphaproteobacteria Bacteria 1R7AM@1224,2U0JN@28211,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T12.39_02259 745310.G432_16750 3.1e-228 798.1 Sphingomonadales Bacteria 1MY4V@1224,2KCUH@204457,2VFNR@28211,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T12.39_02260 876044.IMCC3088_2031 4.5e-46 191.0 unclassified Gammaproteobacteria Bacteria 1J9GJ@118884,1N6CX@1224,1RZAW@1236,COG2866@1,COG2866@2 NA|NA|NA E Protein of unknown function (DUF2817) MAG.T12.39_02261 595536.ADVE02000001_gene1914 1.6e-49 202.6 Alphaproteobacteria Bacteria 1N6CX@1224,2U3MG@28211,COG2866@1,COG2866@2 NA|NA|NA E Protein of unknown function (DUF2817) MAG.T12.39_02262 1502851.FG93_01696 4e-60 238.4 Bradyrhizobiaceae 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1MYEX@1224,2U5YK@28211,3K1PM@41294,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T12.39_02264 1502852.FG94_03406 2.7e-13 82.4 Proteobacteria Bacteria 1NEXN@1224,2E4QM@1,32ZJ7@2 NA|NA|NA MAG.T12.39_02265 1292034.OR37_00474 8.9e-156 556.6 Alphaproteobacteria 3.4.11.19 ko:K01266 ko00000,ko01000,ko01002 Bacteria 1MWDP@1224,2TUI2@28211,COG3191@1,COG3191@2 NA|NA|NA EQ L-aminopeptidase D-esterase MAG.T12.39_02266 1242864.D187_007323 4.3e-125 455.3 Myxococcales Bacteria 1MWP2@1224,2X9WB@28221,2YX2V@29,43DP7@68525,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T12.39_02267 1219035.NT2_07_01510 1.8e-52 213.0 Alphaproteobacteria Bacteria 1QN8Y@1224,2U82N@28211,COG3386@1,COG3386@2 NA|NA|NA G SMP-30 Gluconolaconase MAG.T12.39_02270 1463926.JOCA01000009_gene2777 1.3e-07 64.3 Actinobacteria Bacteria 2DFJ2@1,2HXHF@201174,2ZS1I@2 NA|NA|NA MAG.T12.39_02271 1298864.AUEQ01000001_gene4532 1.3e-54 220.3 Mycobacteriaceae php ko:K07048 ko00000 Bacteria 2360H@1762,2GMZ6@201174,COG1735@1,COG1735@2 NA|NA|NA S Phosphotriesterase MAG.T12.39_02272 983920.Y88_2705 3.8e-287 994.2 Sphingomonadales pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1MUU5@1224,2K18Q@204457,2TRZD@28211,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus MAG.T12.39_02273 1282361.ABAC402_01650 6.8e-153 547.0 Alphaproteobacteria pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUYP@1224,2TT2U@28211,COG0418@1,COG0418@2 NA|NA|NA F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate MAG.T12.39_02274 190650.CC_2536 5.4e-94 350.9 Caulobacterales Bacteria 1RFUA@1224,2KGHJ@204458,2U7P0@28211,COG0330@1,COG0330@2 NA|NA|NA O Stomatin prohibitin-like protein MAG.T12.39_02275 1537715.JQFJ01000002_gene1375 4e-102 378.3 Sphingomonadales fbpC 3.6.3.30 ko:K02010 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 Bacteria 1MU3I@1224,2K5T1@204457,2TQMJ@28211,COG3842@1,COG3842@2 NA|NA|NA E ABC transporter, ATP-binding protein MAG.T12.39_02276 1537715.JQFJ01000002_gene1374 2.3e-167 595.5 Alphaproteobacteria fbpB ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 1MWEV@1224,2TSTS@28211,COG1178@1,COG1178@2 NA|NA|NA P ABC-type Fe3 transport system, permease component MAG.T12.39_02277 1537715.JQFJ01000002_gene1373 2.4e-128 465.3 Sphingomonadales futA1 GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 iJN678.sufA Bacteria 1MUEG@1224,2K8UY@204457,2TR6P@28211,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein MAG.T12.39_02278 1282361.ABAC402_09255 3.8e-194 684.5 Caulobacterales cry2 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1MV9Y@1224,2KG61@204458,2TSDP@28211,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase MAG.T12.39_02279 1248760.ANFZ01000021_gene448 1.4e-130 473.0 Sphingomonadales 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1MUKB@1224,2K01T@204457,2TR6A@28211,COG0415@1,COG0415@2 NA|NA|NA L FAD binding domain of DNA photolyase MAG.T12.39_02280 1121033.AUCF01000005_gene5309 3.6e-117 428.7 Rhodospirillales selA GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 R08219 RC01246 ko00000,ko00001,ko01000 iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006 Bacteria 1MWXI@1224,2JRMS@204441,2TTBH@28211,COG1921@1,COG1921@2 NA|NA|NA E L-seryl-tRNA selenium transferase MAG.T12.39_02281 228405.HNE_2488 3e-127 462.6 Alphaproteobacteria selB ko:K03833 ko00000,ko03012 Bacteria 1MWXH@1224,2TUFY@28211,COG3276@1,COG3276@2 NA|NA|NA J Translation elongation factor MAG.T12.39_02285 69395.JQLZ01000017_gene4226 8.4e-94 350.5 Caulobacterales Bacteria 1PVZJ@1224,2KI7B@204458,2TRAB@28211,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 MAG.T12.39_02286 392499.Swit_4005 4.2e-58 231.5 Sphingomonadales Bacteria 1QYC9@1224,2K513@204457,2TXNE@28211,COG0500@1,COG2226@2 NA|NA|NA Q Sulfotransferase domain MAG.T12.39_02287 450851.PHZ_c0494 1.9e-123 448.7 Caulobacterales rfbF 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 R00956 RC00002 ko00000,ko00001,ko01000 Bacteria 1MUYJ@1224,2KI2U@204458,2TS7U@28211,COG1208@1,COG1208@2 NA|NA|NA M Nucleotidyl transferase MAG.T12.39_02288 450851.PHZ_c0495 1.5e-139 502.7 Caulobacterales rfbG 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 1MV73@1224,2KFFW@204458,2TU81@28211,COG0451@1,COG0451@2 NA|NA|NA M Polysaccharide biosynthesis protein MAG.T12.39_02289 450851.PHZ_c0496 8.4e-176 623.2 Caulobacterales tpm 2.1.1.67 ko:K00569,ko:K16437,ko:K21336 ko00523,ko00983,ko01055,ko01130,map00523,map00983,map01055,map01130 R06627,R08236,R08239,R08246,R11466 RC00003,RC00980,RC01654,RC02277,RC03444 ko00000,ko00001,ko01000 Bacteria 1MVD1@1224,2KHVN@204458,2TUKG@28211,COG0500@1,COG0500@2 NA|NA|NA Q C-methyltransferase C-terminal domain MAG.T12.39_02290 450851.PHZ_c0497 2.6e-57 228.4 Caulobacterales rfbD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008830,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDAB@1224,2KIN3@204458,2U99D@28211,COG1898@1,COG1898@2 NA|NA|NA M dTDP-4-dehydrorhamnose 3,5-epimerase MAG.T12.39_02291 450851.PHZ_c0498 6.3e-86 324.3 Caulobacterales 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1RGNV@1224,2KIHS@204458,2U8I0@28211,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family MAG.T12.39_02292 195253.Syn6312_3691 3.7e-83 315.5 Synechococcus 2.4.1.250 ko:K15521 ko00000,ko01000 Bacteria 1G193@1117,1GZYH@1129,COG0438@1,COG0438@2,COG0457@1,COG0457@2,COG0859@1,COG0859@2 NA|NA|NA M Tetratricopeptide repeat MAG.T12.39_02293 450851.PHZ_c0499 8.3e-185 654.1 Caulobacterales Bacteria 1MVMG@1224,2KGDG@204458,2TRVB@28211,COG0457@1,COG0457@2,COG3914@1,COG3914@2 NA|NA|NA O Glycosyl transferase family 41 MAG.T12.39_02294 1382303.JPOM01000001_gene2403 2.1e-122 446.0 Caulobacterales phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K02484,ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWF3@1224,2KFFM@204458,2TR46@28211,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase MAG.T12.39_02295 450851.PHZ_c0503 1.2e-162 579.7 Caulobacterales pstC ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MVKP@1224,2KFJ7@204458,2TQU1@28211,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane MAG.T12.39_02296 450851.PHZ_c0504 6.5e-171 607.1 Caulobacterales pstA ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MUWB@1224,2KFN4@204458,2TQYQ@28211,COG0581@1,COG0581@2 NA|NA|NA P TIGRFAM phosphate ABC transporter, inner membrane subunit PstA MAG.T12.39_02297 450851.PHZ_c0505 4.5e-117 427.6 Caulobacterales pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 1MU16@1224,2KF4W@204458,2TQX9@28211,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system MAG.T12.39_02298 450851.PHZ_c0506 9.5e-84 316.6 Caulobacterales phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 ko:K02039 ko00000 Bacteria 1MUMI@1224,2KFG1@204458,2TQMN@28211,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake MAG.T12.39_02299 450851.PHZ_c0507 9.7e-100 369.8 Caulobacterales Bacteria 1MY2Z@1224,2KFH3@204458,2TRFZ@28211,COG0745@1,COG0745@2 NA|NA|NA K phosphate regulon transcriptional regulatory protein PhoB MAG.T12.39_02300 450851.PHZ_c0508 8.4e-179 633.3 Caulobacterales purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUAH@1224,2KF99@204458,2TQR5@28211,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family MAG.T12.39_02302 450851.PHZ_c0510 2.8e-159 568.2 Caulobacterales MA20_31030 Bacteria 1MWAK@1224,2KFVA@204458,2TT2N@28211,COG3173@1,COG3173@2 NA|NA|NA S Aminoglycoside phosphotransferase MAG.T12.39_02303 450851.PHZ_c0511 1.5e-128 466.1 Caulobacterales lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 Bacteria 1MU8G@1224,2KFDF@204458,2TTZ4@28211,COG1663@1,COG1663@2 NA|NA|NA F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) MAG.T12.39_02304 450851.PHZ_c0512 1.4e-138 499.6 Caulobacterales kdtA 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 iIT341.HP0957 Bacteria 1MU9F@1224,2KFRV@204458,2TS37@28211,COG1519@1,COG1519@2 NA|NA|NA M transferase MAG.T12.39_02305 509190.Cseg_3853 1.8e-91 342.8 Caulobacterales ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1MVQB@1224,2KF1I@204458,2TR65@28211,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter MAG.T12.39_02306 450851.PHZ_c0514 6.4e-83 313.9 Caulobacterales MA20_05800 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K09778 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 Bacteria 1MZID@1224,2KGVP@204458,2TSGQ@28211,COG2121@1,COG2121@2 NA|NA|NA S Domain of unknown function (DUF374) MAG.T12.39_02307 450851.PHZ_c0515 3.5e-220 771.2 Caulobacterales msbA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02021,ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980 Bacteria 1MUBM@1224,2KF19@204458,2TQMR@28211,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T12.39_02308 450851.PHZ_c0516 1.3e-93 349.4 Caulobacterales 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1REIM@1224,2KFK6@204458,2TVG9@28211,COG2365@1,COG2365@2 NA|NA|NA T Protein tyrosine serine phosphatase MAG.T12.39_02309 1121022.ABENE_18585 4.7e-24 116.7 Caulobacterales suhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,4.99.1.1,4.99.1.9 ko:K01092,ko:K01772 ko00521,ko00562,ko00860,ko01100,ko01110,ko04070,map00521,map00562,map00860,map01100,map01110,map04070 M00121,M00131 R00310,R01185,R01186,R01187,R11329 RC00078,RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1N7D7@1224,2KH8C@204458,2UF6T@28211,COG0483@1,COG0483@2 NA|NA|NA G Domain of unknown function (DUF4170) MAG.T12.39_02310 450851.PHZ_c0519 1.5e-165 589.3 Caulobacterales pmbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 ko:K03592 ko00000,ko01002 Bacteria 1MUVW@1224,2KFDZ@204458,2TSAV@28211,COG0312@1,COG0312@2 NA|NA|NA S Modulator of DNA gyrase MAG.T12.39_02311 450851.PHZ_c0520 3.3e-41 174.5 Caulobacterales ko:K07136 ko00000 Bacteria 1RDHP@1224,2KH4G@204458,2UEVQ@28211,COG3788@1,COG3788@2 NA|NA|NA S MAPEG family MAG.T12.39_02313 566466.NOR53_1150 3.9e-70 271.9 unclassified Gammaproteobacteria Bacteria 1JADP@118884,1PGM7@1224,1RNPA@1236,COG2334@1,COG2334@2 NA|NA|NA S homoserine kinase type II (protein kinase fold) MAG.T12.39_02314 566466.NOR53_1196 4.1e-133 481.5 unclassified Gammaproteobacteria gabT 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1J7IC@118884,1MX0Y@1224,1RQ9Z@1236,COG0160@1,COG0160@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T12.39_02315 1282876.BAOK01000001_gene2956 2.9e-100 372.1 Alphaproteobacteria Bacteria 1MWAK@1224,2TT2N@28211,COG3173@1,COG3173@2 NA|NA|NA S Aminoglycoside phosphotransferase MAG.T12.39_02316 1280946.HY29_02035 4.1e-205 720.7 Hyphomonadaceae HA62_10695 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU2V@1224,2TSK3@28211,43W5F@69657,COG1960@1,COG1960@2 NA|NA|NA I COG1960 Acyl-CoA dehydrogenases MAG.T12.39_02317 1382303.JPOM01000001_gene1408 3.2e-113 415.6 Caulobacterales ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2KJSU@204458,2TVI8@28211,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein MAG.T12.39_02318 247633.GP2143_06659 2.7e-115 422.2 unclassified Gammaproteobacteria Bacteria 1JA9Q@118884,1MX0I@1224,1SMDK@1236,COG1804@1,COG1804@2 NA|NA|NA C acyl-CoA transferases carnitine dehydratase MAG.T12.39_02319 247633.GP2143_13316 6.5e-94 350.9 Gammaproteobacteria ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 1MVG0@1224,1RRC6@1236,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase MAG.T12.39_02320 247633.GP2143_06679 4.3e-161 574.3 Gammaproteobacteria Bacteria 1P8I7@1224,1S15X@1236,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T12.39_02321 1282876.BAOK01000002_gene899 1.2e-114 419.9 Alphaproteobacteria Bacteria 1R7HF@1224,2U3BJ@28211,COG1960@1,COG1960@2 NA|NA|NA I COG1960 Acyl-CoA dehydrogenases MAG.T12.39_02322 1123240.ATVO01000006_gene1369 2.4e-161 575.5 Sphingomonadales ko:K03292 ko00000 2.A.2 Bacteria 1MVUM@1224,2K092@204457,2TVI8@28211,COG2211@1,COG2211@2 NA|NA|NA G COG2211 Na melibiose symporter and related transporters MAG.T12.39_02323 1282876.BAOK01000001_gene3485 2.5e-278 964.5 Alphaproteobacteria fadH 1.3.1.34 ko:K00219 ko00000,ko01000 Bacteria 1MVE0@1224,2TQV0@28211,COG0446@1,COG0446@2,COG1902@1,COG1902@2 NA|NA|NA C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family MAG.T12.39_02324 67593.Physo137019 1.3e-45 190.3 Peronosporales HSD17B4 GO:0001676,GO:0002376,GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008209,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010817,GO:0015031,GO:0015833,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016229,GO:0016491,GO:0016508,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0030258,GO:0031090,GO:0031903,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0033540,GO:0033542,GO:0033559,GO:0033764,GO:0033865,GO:0033875,GO:0033989,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034754,GO:0035337,GO:0035383,GO:0036109,GO:0036111,GO:0036112,GO:0042445,GO:0042579,GO:0042742,GO:0042802,GO:0042803,GO:0042886,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044594,GO:0045087,GO:0045184,GO:0046394,GO:0046395,GO:0046483,GO:0046907,GO:0046983,GO:0050829,GO:0050896,GO:0051179,GO:0051186,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072662,GO:0072663,GO:0080023,GO:0098542,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901568,GO:1901575,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.1.1.35,4.2.1.107,4.2.1.119 ko:K00059,ko:K12405,ko:K14729,ko:K19658,ko:K21768 ko00061,ko00120,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,ko04146,map00061,map00120,map00333,map00780,map01040,map01100,map01130,map01212,map04146 M00083,M00104,M00572 R04533,R04534,R04536,R04543,R04566,R04809,R04810,R04812,R04813,R04953,R04964,R07759,R07763,R09698,R10116,R10120,R11671 RC00029,RC00089,RC00117,RC00770,RC01217 ko00000,ko00001,ko00002,ko01000,ko01004,ko04812 Eukaryota 3QBH9@4776,COG2030@1,KOG1206@2759 NA|NA|NA I N-terminal half of MaoC dehydratase MAG.T12.39_02325 1205680.CAKO01000002_gene2815 7.6e-157 560.5 Rhodospirillales 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1MW3Z@1224,2JP87@204441,2TS56@28211,COG0154@1,COG0154@2 NA|NA|NA J Amidase MAG.T12.39_02326 1123240.ATVO01000006_gene1475 5.6e-151 540.4 Sphingomonadales 1.13.12.16 ko:K00459 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000 Bacteria 1MWPC@1224,2K1CK@204457,2TQRT@28211,COG2070@1,COG2070@2 NA|NA|NA S 2-nitropropane dioxygenase MAG.T12.39_02327 649638.Trad_0506 5.9e-133 481.5 Deinococcus-Thermus ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1WISJ@1297,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T12.39_02328 926560.KE387027_gene1062 2.2e-145 522.7 Deinococcus-Thermus ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1WKZ0@1297,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T12.39_02329 1248916.ANFY01000004_gene1853 3.3e-104 384.8 Sphingomonadales MA20_25215 Bacteria 1MWF6@1224,2K0JE@204457,2TVBC@28211,COG1024@1,COG1024@2 NA|NA|NA I enoyl-CoA hydratase MAG.T12.39_02330 1449049.JONW01000012_gene174 3e-78 298.1 Caulobacterales Bacteria 1QHQD@1224,2KHXP@204458,2U1W2@28211,COG4341@1,COG4341@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. MAG.T12.39_02331 366602.Caul_4338 1.8e-206 726.1 Caulobacterales Bacteria 1QTXJ@1224,2KK7H@204458,2TWFK@28211,COG4773@1,COG4773@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T12.39_02332 551789.ATVJ01000001_gene511 3.6e-217 761.9 Hyphomonadaceae Bacteria 1MU9K@1224,2TS65@28211,43WWT@69657,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P COG1629 Outer membrane receptor proteins, mostly Fe transport MAG.T12.39_02334 1282876.BAOK01000002_gene207 4.7e-131 474.2 Alphaproteobacteria Bacteria 1MUF7@1224,28HWH@1,2TV8Z@28211,2Z82E@2 NA|NA|NA MAG.T12.39_02335 1276756.AUEX01000011_gene1328 1.9e-22 111.7 Betaproteobacteria nbaC GO:0000334,GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0044237,GO:0044248,GO:0051213,GO:0055114 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 Bacteria 1QVVQ@1224,2VQZ6@28216,COG1917@1,COG1917@2 NA|NA|NA S Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate MAG.T12.39_02339 1121124.JNIX01000001_gene986 2.3e-119 435.3 Caulobacterales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MY19@1224,2KFDG@204458,2U2ZW@28211,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T12.39_02340 450851.PHZ_c1070 3.5e-125 454.5 Caulobacterales map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1MU99@1224,2KFFD@204458,2TQTH@28211,COG0024@1,COG0024@2 NA|NA|NA E Methionine aminopeptidase MAG.T12.39_02342 450851.PHZ_c1072 6.3e-91 340.5 Caulobacterales sfsA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K06206 ko00000 Bacteria 1MUC3@1224,2KFVC@204458,2U10V@28211,COG1489@1,COG1489@2 NA|NA|NA S Belongs to the SfsA family MAG.T12.39_02343 450851.PHZ_c1073 4.1e-104 384.4 Caulobacterales cinA 3.5.1.42 ko:K03742 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1MVG6@1224,2KFJE@204458,2TU5C@28211,COG1058@1,COG1058@2 NA|NA|NA S molybdopterin binding domain MAG.T12.39_02344 450851.PHZ_c2241 6.5e-200 704.1 Caulobacterales pmi 2.7.7.13,5.1.3.11,5.3.1.8 ko:K00971,ko:K01809,ko:K16011,ko:K16213 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01445,R01819,R10810 RC00002,RC00289,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV39@1224,2KJVY@204458,2TT0R@28211,COG0836@1,COG0836@2,COG2942@1,COG2942@2 NA|NA|NA G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) MAG.T12.39_02345 450851.PHZ_c2232 3.9e-302 1043.5 Caulobacterales pckG GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007028,GO:0007154,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009267,GO:0009410,GO:0009605,GO:0009607,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010106,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016020,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019725,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030003,GO:0030145,GO:0030154,GO:0030312,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031668,GO:0031669,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033554,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0046916,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050792,GO:0050794,GO:0050801,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0075136,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:0098771,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2638 Bacteria 1MX3C@1224,2KEYC@204458,2TUPJ@28211,COG1274@1,COG1274@2 NA|NA|NA H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle MAG.T12.39_02346 450851.PHZ_c2237 2.8e-137 495.0 Caulobacterales capI 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 R01385 RC00289 ko00000,ko00001,ko01000 Bacteria 1MU7J@1224,2KFNK@204458,2TSIP@28211,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase MAG.T12.39_02347 450851.PHZ_c2231 3.6e-234 817.8 Caulobacterales capD 4.2.1.115 ko:K13013,ko:K15894 ko00520,map00520 R09697 RC02609 ko00000,ko00001,ko01000,ko01005 Bacteria 1MWKY@1224,2KFPH@204458,2TT4K@28211,COG1086@1,COG1086@2 NA|NA|NA M Polysaccharide biosynthesis protein CapD MAG.T12.39_02348 1449049.JONW01000009_gene4465 6.2e-67 260.8 Caulobacterales Bacteria 1R3K7@1224,2APUG@1,2KGMT@204458,2U03X@28211,31EYZ@2 NA|NA|NA S PFAM conserved MAG.T12.39_02349 509190.Cseg_1044 1.7e-108 399.1 Caulobacterales Bacteria 1PEWK@1224,2KG8F@204458,2TV4E@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_02350 450851.PHZ_c2263 1.4e-154 552.4 Caulobacterales cysD 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUCZ@1224,2KG42@204458,2TT2D@28211,COG0175@1,COG0175@2 NA|NA|NA H Sulfate adenylyltransferase MAG.T12.39_02351 450851.PHZ_c2264 2.4e-291 1007.7 Caulobacterales cysC 2.7.1.25,2.7.7.4 ko:K00860,ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUD9@1224,2KF08@204458,2TQNJ@28211,COG0529@1,COG0529@2,COG2895@1,COG2895@2 NA|NA|NA H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily MAG.T12.39_02352 1449049.JONW01000005_gene799 1.3e-70 272.3 Caulobacterales queF 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 R07605 RC01875 ko00000,ko00001,ko01000,ko03016 Bacteria 1MW0M@1224,2KGE5@204458,2U57X@28211,COG0780@1,COG0780@2 NA|NA|NA S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) MAG.T12.39_02353 450851.PHZ_c2227 3.6e-66 258.1 Caulobacterales ydjA Bacteria 1PKUV@1224,2KGIB@204458,2U5MZ@28211,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase MAG.T12.39_02354 450851.PHZ_c2225 9.2e-126 456.4 Caulobacterales cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFX@1224,2KFBI@204458,2TQQ5@28211,COG1045@1,COG1045@2 NA|NA|NA E serine acetyltransferase MAG.T12.39_02355 450851.PHZ_c2224 1e-25 122.1 Caulobacterales MA20_32250 Bacteria 1N7QS@1224,2E4B6@1,2KHCX@204458,2UFNH@28211,32Z6W@2 NA|NA|NA S Protein of unknown function (DUF3126) MAG.T12.39_02356 450851.PHZ_c1106 7.4e-114 416.8 Caulobacterales ko:K06217 ko00000 Bacteria 1MWMU@1224,2KFPX@204458,2TSYC@28211,COG1702@1,COG1702@2 NA|NA|NA T PFAM PhoH family protein MAG.T12.39_02357 450851.PHZ_c1107 4.1e-63 247.7 Caulobacterales yrdA Bacteria 1RD76@1224,2KG9R@204458,2U5GR@28211,COG0663@1,COG0663@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) MAG.T12.39_02358 450851.PHZ_c1108 6.6e-118 430.3 Alphaproteobacteria caiD 2.3.1.9,4.2.1.149 ko:K00626,ko:K08299 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R10675 RC00004,RC00326,RC01095 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MWZC@1224,2TRIH@28211,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T12.39_02359 450851.PHZ_c1110 6.4e-248 863.2 Caulobacterales betA 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV19@1224,2KFEH@204458,2TQKQ@28211,COG2303@1,COG2303@2 NA|NA|NA E Belongs to the GMC oxidoreductase family MAG.T12.39_02360 450851.PHZ_c1112 4.7e-270 937.6 Caulobacterales yhjJ ko:K07263 ko00000,ko01000,ko01002 Bacteria 1NAH6@1224,2KFX1@204458,2U0S5@28211,COG0612@1,COG0612@2 NA|NA|NA S Belongs to the peptidase M16 family MAG.T12.39_02361 69395.JQLZ01000003_gene3 6.8e-31 141.0 Caulobacterales MA20_31620 Bacteria 1PRTR@1224,2KGTZ@204458,2UDJA@28211,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family MAG.T12.39_02364 59538.XP_005973739.1 6.7e-169 600.5 Cetartiodactyla Mammalia 39RWD@33154,3BEKC@33208,3CSZJ@33213,3J52B@40674,4818N@7711,493PC@7742,4IYI2@91561,COG0624@1,KOG2275@2759 NA|NA|NA E Carboxypeptidase MAG.T12.39_02365 1500259.JQLD01000001_gene4151 1.6e-85 323.2 Rhizobiaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1MWPQ@1224,2TTPI@28211,4B7NA@82115,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolases, choloylglycine hydrolase family MAG.T12.39_02366 509190.Cseg_0886 5.5e-50 203.8 Caulobacterales Bacteria 1MZN2@1224,2KGG8@204458,2UBTA@28211,COG5319@1,COG5319@2 NA|NA|NA S Protein of unknown function (DUF1178) MAG.T12.39_02367 450851.PHZ_c0770 3e-100 371.7 Caulobacterales ramA 3.5.1.77,3.5.5.1 ko:K01459,ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 Bacteria 1MUUB@1224,2KG0R@204458,2TRGZ@28211,COG0388@1,COG0388@2 NA|NA|NA S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase MAG.T12.39_02368 450851.PHZ_c0769 4.8e-25 120.2 Caulobacterales grxC GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681 ko:K03676 ko00000,ko03110 Bacteria 1N72P@1224,2KH13@204458,2UFM1@28211,COG0695@1,COG0695@2 NA|NA|NA O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins MAG.T12.39_02369 450851.PHZ_c0768 2.7e-79 302.0 Caulobacterales comF 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1RHAV@1224,2KGC0@204458,2TV7G@28211,COG1040@1,COG1040@2 NA|NA|NA S Phosphoribosyl transferase domain MAG.T12.39_02370 1449049.JONW01000008_gene625 1.7e-100 372.5 Caulobacterales Bacteria 1QUNM@1224,2KF32@204458,2TW20@28211,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain MAG.T12.39_02371 509190.Cseg_0938 2.1e-71 275.8 Caulobacterales 2.7.1.31 ko:K07452,ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 1QUTA@1224,2KG9T@204458,2U4WP@28211,COG4240@1,COG4240@2 NA|NA|NA S COG4240 Predicted kinase MAG.T12.39_02372 69395.JQLZ01000001_gene3292 2.8e-59 234.6 Caulobacterales mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 ko:K03574,ko:K08320 ko00000,ko01000,ko03400 iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 Bacteria 1RCZM@1224,2KGGS@204458,2U7A4@28211,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family MAG.T12.39_02373 450851.PHZ_c0764 9.6e-179 633.3 Caulobacterales rhlE2 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MU49@1224,2KF7X@204458,2TR6Q@28211,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase MAG.T12.39_02374 1292034.OR37_03016 5.7e-153 547.4 Caulobacterales argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1783 Bacteria 1MU0T@1224,2KFNS@204458,2TS98@28211,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate MAG.T12.39_02375 69395.JQLZ01000001_gene3301 6.3e-102 377.5 Caulobacterales 3.1.3.16,5.2.1.8 ko:K03769,ko:K07533,ko:K20074 ko00000,ko01000,ko01009,ko03110 Bacteria 1MZDK@1224,2KG5E@204458,2TVQD@28211,COG0760@1,COG0760@2 NA|NA|NA M peptidylprolyl isomerase MAG.T12.39_02376 450851.PHZ_c0758 0.0 1493.8 Caulobacterales secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1MUJZ@1224,2KFEE@204458,2TTBF@28211,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane MAG.T12.39_02377 1292034.OR37_00035 9.9e-45 186.0 Caulobacterales yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1MZ6S@1224,2KGZB@204458,2U98B@28211,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family MAG.T12.39_02378 1292034.OR37_03496 1.7e-34 152.1 Alphaproteobacteria Bacteria 1NBJ9@1224,2UFXN@28211,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T12.39_02379 1038859.AXAU01000005_gene5317 1.5e-95 356.3 Bradyrhizobiaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MXRX@1224,2TRSQ@28211,3JSKI@41294,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T12.39_02380 420662.Mpe_A0982 8.2e-151 540.4 unclassified Burkholderiales bam 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1KNK5@119065,1MW3Z@1224,2W9HQ@28216,COG0154@1,COG0154@2 NA|NA|NA J Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit MAG.T12.39_02381 258594.RPA3409 3.2e-171 608.6 Alphaproteobacteria nfdA_2 Bacteria 1R53N@1224,2VF84@28211,COG1574@1,COG1574@2 NA|NA|NA S metal-dependent hydrolase with the TIM-barrel fold MAG.T12.39_02382 450851.PHZ_c3050 0.0 1157.9 Caulobacterales accA3_1 2.1.3.15,6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 ko:K01961,ko:K01966,ko:K01969 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00036,M00082,M00373,M00376,M00741 R00742,R01859,R04138,R04385 RC00040,RC00097,RC00253,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4H@1224,2KFW8@204458,2TWYZ@28211,COG0439@1,COG0439@2,COG4799@1,COG4799@2 NA|NA|NA I Biotin carboxylase C-terminal domain MAG.T12.39_02383 702113.PP1Y_Mpl6370 2.8e-169 601.7 Sphingomonadales 3.1.6.4 ko:K01132 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00077,M00079 R07806 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUJH@1224,2K365@204457,2TSB8@28211,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T12.39_02384 366602.Caul_3644 2.8e-76 292.4 Caulobacterales ko:K13572 ko00000,ko03051 Bacteria 1R674@1224,2KJU3@204458,2TTWA@28211,COG2378@1,COG2378@2 NA|NA|NA K WYL domain MAG.T12.39_02385 639283.Snov_2952 7.6e-27 126.7 Xanthobacteraceae Bacteria 1N372@1224,2DVPK@1,2UCGK@28211,32UZW@2,3F1P6@335928 NA|NA|NA MAG.T12.39_02387 1276756.AUEX01000001_gene1150 2.5e-54 218.8 Comamonadaceae Bacteria 1RHQN@1224,2VMQN@28216,4ADD5@80864,COG2860@1,COG2860@2 NA|NA|NA S UPF0126 domain MAG.T12.39_02388 398525.KB900701_gene2386 5.6e-59 234.2 Bradyrhizobiaceae 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU6H@1224,2TU48@28211,3JU1J@41294,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T12.39_02390 450851.PHZ_c3072 1.3e-26 126.3 Alphaproteobacteria Bacteria 1NCAB@1224,2CGTC@1,2UIBS@28211,331SF@2 NA|NA|NA MAG.T12.39_02391 247633.GP2143_13016 5.8e-175 620.9 Gammaproteobacteria Bacteria 1MU6G@1224,1RSC1@1236,COG0318@1,COG0318@2 NA|NA|NA IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II MAG.T12.39_02392 1248760.ANFZ01000014_gene2098 1.2e-120 439.9 Sphingomonadales Bacteria 1R7M8@1224,2KCQD@204457,2TS45@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, N-terminal domain MAG.T12.39_02393 1282876.BAOK01000001_gene3487 2.2e-160 572.0 Alphaproteobacteria Bacteria 1R3VD@1224,2U2WQ@28211,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T12.39_02394 1408164.MOLA814_00431 2.5e-75 288.5 unclassified Betaproteobacteria MA20_22970 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1KR6S@119066,1RA05@1224,2VQRT@28216,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain MAG.T12.39_02395 1280950.HJO_05580 3.8e-115 421.4 Hyphomonadaceae MA20_34740 Bacteria 1MV5I@1224,2TREB@28211,43ZA3@69657,COG0714@1,COG0714@2 NA|NA|NA S AAA ATPase MAG.T12.39_02396 1280944.HY17_14050 1.8e-113 416.4 Hyphomonadaceae MA20_34745 ko:K07161 ko00000 Bacteria 1MUHH@1224,2U05M@28211,43ZK8@69657,COG3552@1,COG3552@2 NA|NA|NA S COG3552 Protein containing von Willebrand factor type A (vWA) domain MAG.T12.39_02397 1110502.TMO_1296 1.2e-77 296.6 Rhodospirillales MA20_04540 Bacteria 1MW86@1224,2JWEV@204441,2TSEM@28211,COG4221@1,COG4221@2 NA|NA|NA S KR domain MAG.T12.39_02398 702113.PP1Y_Mpl6635 3.1e-14 85.1 Sphingomonadales Bacteria 1N7NP@1224,2CBAE@1,2KBAD@204457,2UH5V@28211,32YK1@2 NA|NA|NA MAG.T12.39_02399 450851.PHZ_c1167 9.9e-36 156.8 Bacteria Bacteria 2CBAE@1,32T11@2 NA|NA|NA MAG.T12.39_02400 247633.GP2143_18131 1.3e-49 202.6 Bacteria Bacteria 2C42J@1,3359Y@2 NA|NA|NA MAG.T12.39_02401 450851.PHZ_c2572 4e-105 387.9 Alphaproteobacteria Bacteria 1R8PG@1224,28MSC@1,2VG09@28211,2ZB0S@2 NA|NA|NA MAG.T12.39_02402 450851.PHZ_c3217 0.0 1112.1 Caulobacterales 1.1.1.157,1.1.1.35 ko:K00074,ko:K07516 ko00071,ko00360,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00360,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R01976,R04737,R04739,R04741,R04743,R04745,R04748,R05305,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9P@1224,2KG35@204458,2TS8E@28211,COG1024@1,COG1024@2,COG1250@1,COG1250@2 NA|NA|NA I Enoyl-CoA hydratase isomerase family MAG.T12.39_02403 366602.Caul_1092 2.2e-224 785.0 Caulobacterales mtbA ko:K03761 ko00000,ko02000 2.A.1.6.2 Bacteria 1MU46@1224,2KG4D@204458,2TRAP@28211,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T12.39_02404 316058.RPB_0861 1.6e-116 426.8 Bradyrhizobiaceae Bacteria 1MUMZ@1224,2TRUI@28211,3JR8W@41294,COG0457@1,COG0457@2,COG3629@1,COG3629@2,COG5616@1,COG5616@2 NA|NA|NA T Adenylate cyclase MAG.T12.39_02405 316057.RPD_0969 4.5e-257 895.2 Bradyrhizobiaceae ko:K07223 ko00000 Bacteria 1MXKF@1224,2TTJE@28211,3JSYV@41294,COG2124@1,COG2124@2,COG2837@1,COG2837@2 NA|NA|NA P peroxidase MAG.T12.39_02406 450851.PHZ_c3193 2.6e-189 667.9 Caulobacterales fba 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1MURX@1224,2KFVW@204458,2TSAD@28211,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase, class II, Calvin cycle subtype MAG.T12.39_02407 1382303.JPOM01000001_gene206 9.7e-161 573.2 Caulobacterales pgk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUNU@1224,2KFA0@204458,2TSKQ@28211,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family MAG.T12.39_02408 1446473.JHWH01000001_gene1151 1.2e-111 409.5 Paracoccus gap 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1MU93@1224,2PW2K@265,2TR6E@28211,COG0057@1,COG0057@2 NA|NA|NA G catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate MAG.T12.39_02409 190650.CC_3549 2.7e-270 937.9 Caulobacterales maeB 1.1.1.38,1.1.1.40,2.3.1.8 ko:K00027,ko:K00029,ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020 M00169,M00172,M00357,M00579 R00214,R00216,R00230,R00921 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1637 Bacteria 1MU0A@1224,2KFDX@204458,2TQJT@28211,COG0280@1,COG0280@2,COG0281@1,COG0281@2 NA|NA|NA C Phosphate acetyl butaryl transferase MAG.T12.39_02410 450851.PHZ_c3497 6e-80 304.7 Caulobacterales tqsA Bacteria 1MXXU@1224,2KF24@204458,2TQJJ@28211,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T12.39_02411 450851.PHZ_c3496 5e-191 674.1 Caulobacterales yjgR ko:K06915,ko:K19172 ko00000,ko02048 Bacteria 1MU59@1224,2KFCG@204458,2TRU8@28211,COG0433@1,COG0433@2 NA|NA|NA S Bacterial protein of unknown function (DUF853) MAG.T12.39_02412 1292034.OR37_04046 1.1e-125 456.1 Caulobacterales Bacteria 1MUBQ@1224,2KFSZ@204458,2TRPN@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenase MAG.T12.39_02413 450851.PHZ_c3493 5.8e-44 183.7 Caulobacterales Bacteria 1MZR5@1224,2KGW2@204458,2UCIB@28211,COG3339@1,COG3339@2 NA|NA|NA S Protein of unknown function (DUF1232) MAG.T12.39_02414 450851.PHZ_c3492 1.9e-113 415.6 Caulobacterales Bacteria 1MZXM@1224,2KGP5@204458,2U8WM@28211,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T12.39_02415 450851.PHZ_c3491 1.5e-115 422.5 Caulobacterales Bacteria 1R4GD@1224,2KFS3@204458,2TVNF@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T12.39_02416 450851.PHZ_c3489 1.3e-134 486.1 Caulobacterales qor2 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1MWRK@1224,2KG4W@204458,2TQMF@28211,COG0604@1,COG0604@2 NA|NA|NA C PFAM Alcohol dehydrogenase zinc-binding domain protein MAG.T12.39_02417 450851.PHZ_c3488 3e-178 631.3 Caulobacterales rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 1MUYK@1224,2KFT3@204458,2TQT3@28211,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T12.39_02418 1449049.JONW01000005_gene1681 2.4e-37 161.8 Caulobacterales yjfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08989 ko00000 Bacteria 1RJKS@1224,2KGQU@204458,2UBJI@28211,COG3766@1,COG3766@2 NA|NA|NA S Domain of Unknown Function (DUF350) MAG.T12.39_02419 450851.PHZ_c3486 4.3e-91 341.3 Caulobacterales 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1P55H@1224,2KFTT@204458,2U4M5@28211,COG0265@1,COG0265@2 NA|NA|NA O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain MAG.T12.39_02420 450851.PHZ_c3447 5.8e-86 323.9 Caulobacterales trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 1MUWJ@1224,2KG30@204458,2TUU9@28211,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA MAG.T12.39_02421 450851.PHZ_c3448 2e-190 671.8 Caulobacterales metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUFQ@1224,2KFMZ@204458,2TR4P@28211,COG0192@1,COG0192@2 NA|NA|NA H Belongs to the AdoMet synthase family MAG.T12.39_02422 450851.PHZ_c3450 2.9e-160 572.0 Caulobacterales lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K03820 ko00000,ko01000 GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 Bacteria 1MUBU@1224,2KF5E@204458,2TQRC@28211,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins MAG.T12.39_02423 366602.Caul_0024 1.4e-92 346.3 Caulobacterales tlyC ko:K06189 ko00000,ko02000 9.A.40.1.2 Bacteria 1MV3P@1224,2KGCE@204458,2TVFA@28211,COG1253@1,COG1253@2 NA|NA|NA S CBS domain MAG.T12.39_02424 450851.PHZ_c3452 3.4e-43 181.4 Caulobacterales ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1MZ67@1224,2KGPK@204458,2UBXV@28211,COG0319@1,COG0319@2 NA|NA|NA J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA MAG.T12.39_02425 450851.PHZ_c3453 3.1e-133 481.5 Caulobacterales phoH ko:K06217 ko00000 Bacteria 1MVDV@1224,2KFK3@204458,2TRV3@28211,COG1702@1,COG1702@2 NA|NA|NA T Phosphate starvation protein PhoH MAG.T12.39_02426 450851.PHZ_c3454 4.2e-200 704.1 Caulobacterales miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 1MURS@1224,2KFJ0@204458,2TQN6@28211,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine MAG.T12.39_02427 450851.PHZ_c3455 1.5e-60 238.8 Caulobacterales fur ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1RDWJ@1224,2KGG1@204458,2U6ZS@28211,COG0735@1,COG0735@2 NA|NA|NA K Belongs to the Fur family MAG.T12.39_02428 1292034.OR37_01709 8.9e-24 116.7 Caulobacterales rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 1RIE6@1224,2KH9N@204458,2UF5C@28211,COG0454@1,COG0456@2 NA|NA|NA K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 MAG.T12.39_02429 450851.PHZ_c3457 7.6e-40 170.6 Caulobacterales yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1MXPH@1224,2KGSU@204458,2TTM2@28211,COG1214@1,COG1214@2 NA|NA|NA O PFAM peptidase M22 glycoprotease MAG.T12.39_02430 450851.PHZ_c3458 3.1e-77 294.7 Caulobacterales nifU Bacteria 1MVQ1@1224,2KG9I@204458,2TUD1@28211,COG0694@1,COG0694@2 NA|NA|NA O Scaffold protein Nfu NifU MAG.T12.39_02431 450851.PHZ_c0050 1.5e-275 955.3 Caulobacterales kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1MUVH@1224,2KF5G@204458,2TRVJ@28211,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell MAG.T12.39_02432 311403.Arad_1098 6.6e-68 263.5 Rhizobiaceae lrp_3 ko:K03719,ko:K05800 ko00000,ko03000,ko03036 Bacteria 1RHK5@1224,2U9JJ@28211,4BMG0@82115,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T12.39_02434 450851.PHZ_c2589 4.1e-47 194.5 Caulobacterales Bacteria 1QZRM@1224,2KK8P@204458,2TYD1@28211,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain MAG.T12.39_02435 450851.PHZ_c2590 3.8e-97 361.3 Caulobacterales Bacteria 1MUPX@1224,2KFEA@204458,2TT6C@28211,COG1028@1,COG1028@2 NA|NA|NA IQ short-chain dehydrogenase MAG.T12.39_02436 450851.PHZ_c2591 2.3e-55 221.9 Alphaproteobacteria Bacteria 1Q3U4@1224,2UIA6@28211,COG0645@1,COG0645@2 NA|NA|NA S AAA domain MAG.T12.39_02437 450851.PHZ_c1115 1.5e-192 679.5 Caulobacterales mrcB 2.4.1.129,3.4.16.4 ko:K03814,ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1QTST@1224,2KHQC@204458,2TQQ8@28211,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase MAG.T12.39_02438 450851.PHZ_c2593 3.5e-71 274.2 Caulobacterales greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 1RCXW@1224,2KGAN@204458,2U5JU@28211,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides MAG.T12.39_02439 1449049.JONW01000005_gene1333 4.7e-97 361.3 Caulobacterales ko:K07276 ko00000 Bacteria 1R70U@1224,2KF7S@204458,2TQWV@28211,COG3660@1,COG3660@2 NA|NA|NA M Mitochondrial fission ELM1 MAG.T12.39_02440 450851.PHZ_c2595 8.3e-100 370.5 Caulobacterales pseG Bacteria 1Q330@1224,2KHBF@204458,2U781@28211,COG3980@1,COG3980@2 NA|NA|NA M TIGRFAM pseudaminic acid biosynthesis-associated protein PseG MAG.T12.39_02441 1123240.ATVO01000004_gene1028 5.1e-13 81.6 Sphingomonadales ko:K03668 ko00000 Bacteria 1NGG1@1224,2K82S@204457,2UJJM@28211,COG3187@1,COG3187@2 NA|NA|NA O META domain MAG.T12.39_02442 450851.PHZ_c2603 5.5e-154 550.4 Caulobacterales trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 1MV15@1224,2KFV8@204458,2TRBW@28211,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family MAG.T12.39_02443 757424.Hsero_4502 7e-173 613.6 Oxalobacteraceae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1MUH7@1224,2VKDB@28216,478PB@75682,COG0766@1,COG0766@2 NA|NA|NA M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) MAG.T12.39_02444 450851.PHZ_c2604 3.4e-43 181.4 Caulobacterales ko:K03824,ko:K09964 ko00000,ko01000 Bacteria 1RA42@1224,2KHGF@204458,2VA6Q@28211,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) domain MAG.T12.39_02445 450851.PHZ_c2605 4e-95 355.1 Caulobacterales cwlJ 3.5.1.28 ko:K01449 R04112 RC00064,RC00141 ko00000,ko01000 Bacteria 1MWX3@1224,2KG92@204458,2TT15@28211,COG3773@1,COG3773@2 NA|NA|NA M cell wall hydrolase MAG.T12.39_02446 450851.PHZ_c2607 9.5e-171 606.3 Caulobacterales nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iHN637.CLJU_RS12020,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919 Bacteria 1MWQU@1224,2KF4X@204458,2TRPG@28211,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate MAG.T12.39_02447 450851.PHZ_c2608 2.7e-168 598.6 Caulobacterales nadB GO:0008150,GO:0040007 1.3.5.4,1.4.3.16,2.4.2.19 ko:K00244,ko:K00278,ko:K00767 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164,R03348 RC00006,RC00045,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1595 Bacteria 1RBQW@1224,2KF91@204458,2TS0E@28211,COG0029@1,COG0029@2 NA|NA|NA H PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein MAG.T12.39_02448 190650.CC_2915 8.2e-106 390.2 Caulobacterales nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0C@1224,2KFMV@204458,2TS7C@28211,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family MAG.T12.39_02449 450851.PHZ_c2616 1.4e-46 193.4 Caulobacterales cwlJ 3.5.1.28 ko:K01449 R04112 RC00064,RC00141 ko00000,ko01000 Bacteria 1MWX3@1224,2KGB3@204458,2TT15@28211,COG3773@1,COG3773@2 NA|NA|NA M cell wall hydrolase MAG.T12.39_02450 450851.PHZ_c0580 1e-41 176.8 Caulobacterales dsbA Bacteria 1RFF4@1224,2KGJX@204458,2U5BN@28211,COG1651@1,COG1651@2 NA|NA|NA O DSBA oxidoreductase MAG.T12.39_02452 987059.RBXJA2T_04138 1.4e-146 525.8 unclassified Burkholderiales alkK2 6.2.1.44 ko:K00666,ko:K20034 ko00920,map00920 R10820 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 Bacteria 1KIY7@119065,1MUMC@1224,2VGZE@28216,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase MAG.T12.39_02454 1292034.OR37_02630 1.1e-111 409.8 Caulobacterales MA20_07390 3.1.2.6 ko:K01069,ko:K07455 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVC3@1224,2KFMD@204458,2TUAZ@28211,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T12.39_02455 69395.JQLZ01000001_gene3111 5.4e-34 150.6 Caulobacterales blh 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 1N9AF@1224,2KGXR@204458,2UD2M@28211,COG3453@1,COG3453@2 NA|NA|NA S Putative phosphatase (DUF442) MAG.T12.39_02456 1178482.BJB45_00960 2.2e-96 359.0 Oceanospirillales oppB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1MU8Z@1224,1RNJ1@1236,1XJ29@135619,COG0601@1,COG0601@2 NA|NA|NA P transporter, permease MAG.T12.39_02457 1479238.JQMZ01000001_gene2106 1e-95 356.7 Hyphomonadaceae oppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1MU26@1224,2TTEV@28211,43WYG@69657,COG1173@1,COG1173@2 NA|NA|NA EP With OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell MAG.T12.39_02458 450851.PHZ_c2732 7.4e-38 163.7 Caulobacterales Bacteria 1N20S@1224,2DTSK@1,2KH1K@204458,2UCXK@28211,32UVT@2 NA|NA|NA MAG.T12.39_02459 414684.RC1_0580 0.0 1233.4 Alphaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MU9K@1224,2TTJG@28211,COG1629@1,COG4206@1,COG4206@2,COG4771@2 NA|NA|NA P receptor MAG.T12.39_02460 450851.PHZ_c2729 1.1e-187 663.3 Caulobacterales sppA ko:K04773 ko00000,ko01000,ko01002 Bacteria 1MUXE@1224,2KF3R@204458,2TSXA@28211,COG0616@1,COG0616@2 NA|NA|NA OU signal peptide peptidase MAG.T12.39_02461 1121106.JQKB01000006_gene1275 9.8e-118 429.9 Rhodospirillales MA20_23235 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 R05320 RC01331 ko00000,ko00001,ko01000 Bacteria 1MV5K@1224,2JSGW@204441,2TQTZ@28211,COG2175@1,COG2175@2 NA|NA|NA Q Taurine catabolism dioxygenase TauD, TfdA family MAG.T12.39_02464 1035191.HMPREF0185_01552 1.3e-101 376.7 Alphaproteobacteria intD Bacteria 1R7GV@1224,2TT06@28211,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T12.39_02469 1382303.JPOM01000001_gene1610 1.4e-169 602.8 Caulobacterales phrB GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1MV9Y@1224,2KG61@204458,2TSDP@28211,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase MAG.T12.39_02470 450851.PHZ_c2501 4.3e-35 154.1 Caulobacterales Bacteria 1N1D4@1224,2KJ3Y@204458,2UBYV@28211,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase-like domain MAG.T12.39_02471 509190.Cseg_1225 8.5e-60 236.9 Caulobacterales gst1 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1PHM1@1224,2KGI9@204458,2TTQZ@28211,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase MAG.T12.39_02472 1449049.JONW01000010_gene3587 2.8e-143 515.4 Caulobacterales Bacteria 1MWYR@1224,2KIC4@204458,2TSXW@28211,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily MAG.T12.39_02473 1449049.JONW01000012_gene117 1.6e-30 139.0 Caulobacterales Bacteria 1NJUI@1224,2EHX7@1,2KIYE@204458,2UIZW@28211,33BNT@2 NA|NA|NA MAG.T12.39_02474 450851.PHZ_c1118 2.4e-99 368.6 Caulobacterales Bacteria 1MX8B@1224,2KJZA@204458,2U26N@28211,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T12.39_02475 1165096.ARWF01000001_gene2242 4.6e-22 111.3 Nitrosomonadales ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1RFWV@1224,2KNSM@206350,2VRDS@28216,COG2885@1,COG2885@2 NA|NA|NA M OmpA family MAG.T12.39_02476 666681.M301_0649 6.9e-21 107.1 Betaproteobacteria rplU ko:K02879,ko:K02888,ko:K02890,ko:K02899,ko:K02967,ko:K04074 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011,ko03036 Bacteria 1NNMM@1224,2VYMS@28216,COG3743@1,COG3743@2 NA|NA|NA S rRNA binding MAG.T12.39_02477 1282876.BAOK01000001_gene2100 1.2e-158 566.2 Alphaproteobacteria Bacteria 1P6G6@1224,2TU10@28211,COG2159@1,COG2159@2 NA|NA|NA S metal-dependent hydrolase of the TIM-barrel fold MAG.T12.39_02478 1219035.NT2_06_01780 4.3e-30 136.7 Proteobacteria Bacteria 1QVBI@1224,COG1813@1,COG1813@2 NA|NA|NA K Transcriptional regulator MAG.T12.39_02479 1219035.NT2_06_01790 1.3e-213 748.8 Sphingomonadales 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1N458@1224,2K4RK@204457,2TVQF@28211,COG3550@1,COG3550@2 NA|NA|NA S Pfam:HipA_N MAG.T12.39_02480 1224746.B932_1634 2.7e-106 392.5 Alphaproteobacteria Bacteria 1R44F@1224,2U1J2@28211,COG3344@1,COG3344@2 NA|NA|NA L Reverse transcriptase (RNA-dependent DNA polymerase) MAG.T12.39_02481 1333998.M2A_2179 1.3e-149 536.2 Alphaproteobacteria MA20_04655 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVJC@1224,2TQRA@28211,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T12.39_02482 450851.PHZ_c1098 9.7e-196 689.5 Caulobacterales MA20_45145 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5G@1224,2KFPU@204458,2TS1R@28211,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T12.39_02483 272568.GDI1146 4.1e-29 133.7 Rhodospirillales VL23_11275 Bacteria 1MZVQ@1224,2CC0C@1,2JXTJ@204441,2UBWU@28211,32RUG@2 NA|NA|NA S Protein of unknown function (DUF3297) MAG.T12.39_02484 450851.PHZ_c1751 1.2e-147 529.3 Caulobacterales pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 1MUIT@1224,2KFQF@204458,2TS4Y@28211,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates MAG.T12.39_02485 450851.PHZ_c1749 9.8e-25 118.6 Caulobacterales rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1PU3Y@1224,2KHBQ@204458,2UF54@28211,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family MAG.T12.39_02486 450851.PHZ_c1748 1.2e-100 372.9 Caulobacterales 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1N4N7@1224,2KF8D@204458,2TS6T@28211,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T12.39_02487 1122970.AUHC01000001_gene840 0.0 1084.7 Sphingomonadales Bacteria 1MVFB@1224,2KEE4@204457,2U1V9@28211,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T12.39_02488 426117.M446_2478 1.3e-17 95.5 Bacteria ko:K09803 ko00000 Bacteria COG2929@1,COG2929@2 NA|NA|NA S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system MAG.T12.39_02489 176299.Atu1735 4.2e-25 120.9 Rhizobiaceae ko:K07726 ko00000,ko03000 Bacteria 1N802@1224,2UGPM@28211,4BG8S@82115,COG2944@1,COG2944@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T12.39_02490 261292.Nit79A3_1359 4e-41 174.9 Betaproteobacteria Bacteria 1N6Q2@1224,2VYRF@28216,COG3722@1,COG3722@2 NA|NA|NA K Mannitol repressor MAG.T12.39_02491 450851.PHZ_c1747 4e-197 694.1 Caulobacterales eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1MU1N@1224,2KEYP@204458,2TR04@28211,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis MAG.T12.39_02492 450851.PHZ_c1745 3e-23 114.4 Caulobacterales MA20_41765 Bacteria 1PTEW@1224,2KH94@204458,2UGIU@28211,COG2919@1,COG2919@2 NA|NA|NA D PFAM Septum formation initiator MAG.T12.39_02493 450851.PHZ_c1744 3.5e-159 567.8 Caulobacterales pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5R@1224,2KEZE@204458,2TRSS@28211,COG1071@1,COG1071@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T12.39_02494 1121123.AUAO01000003_gene2103 3.2e-176 624.8 Caulobacterales pdhB 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2753 Bacteria 1R8KB@1224,2KFI5@204458,2TRMR@28211,COG0022@1,COG0022@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 MAG.T12.39_02495 1382303.JPOM01000001_gene1312 2.9e-34 151.0 Caulobacterales Bacteria 1RHWZ@1224,2KK45@204458,2UBDG@28211,COG3791@1,COG3791@2 NA|NA|NA S Glutathione-dependent formaldehyde-activating enzyme MAG.T12.39_02496 1035191.HMPREF0185_03322 1.2e-145 523.1 Caulobacterales pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MUGY@1224,2KG5R@204458,2TRXM@28211,COG0508@1,COG0508@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T12.39_02497 69395.JQLZ01000003_gene309 7e-27 125.9 Caulobacterales ko:K03704 ko00000,ko03000 Bacteria 1N6Q5@1224,2KH7U@204458,2UF6W@28211,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain MAG.T12.39_02498 450851.PHZ_c2580 8.8e-183 646.4 Caulobacterales carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1950,iNJ661.Rv1383,iUTI89_1310.UTI89_C0036,ic_1306.c0040 Bacteria 1MUB9@1224,2KG53@204458,2TR3W@28211,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family MAG.T12.39_02499 450851.PHZ_c2581 2.5e-58 231.5 Caulobacterales MA20_23360 Bacteria 1MWI7@1224,2KGGK@204458,2U0S6@28211,COG5470@1,COG5470@2 NA|NA|NA S Domain of unknown function (DUF1330) MAG.T12.39_02500 450851.PHZ_c2583 5e-93 347.4 Caulobacterales ko:K07025 ko00000 Bacteria 1MX48@1224,2KGB1@204458,2TUWQ@28211,COG1011@1,COG1011@2 NA|NA|NA S PFAM Haloacid dehalogenase domain protein hydrolase MAG.T12.39_02501 450851.PHZ_c2576 1.6e-207 729.2 Caulobacterales dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1MUHC@1224,2KF9P@204458,2TRU2@28211,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication MAG.T12.39_02502 59538.XP_005979123.1 5.9e-301 1039.6 Bilateria Metazoa 2QVXR@2759,3ABZU@33154,3BVK8@33208,3DDPS@33213,COG0568@1 NA|NA|NA K RNA polymerase sigma factor MAG.T12.39_02503 450851.PHZ_c2573 1.6e-82 312.4 Caulobacterales Bacteria 1MX57@1224,28H7B@1,2KGB4@204458,2TQZS@28211,2Z7JJ@2 NA|NA|NA S Putative 2OG-Fe(II) oxygenase MAG.T12.39_02504 69395.JQLZ01000003_gene294 2.1e-08 64.7 Caulobacterales Bacteria 1NHSI@1224,2KJG3@204458,2UN8I@28211,33M0E@2,COG1749@1 NA|NA|NA N Flagellar basal body rod FlgEFG protein C-terminal MAG.T12.39_02506 366602.Caul_4060 7.5e-39 167.9 Caulobacterales gumN ko:K09973 ko00000 Bacteria 1N8WD@1224,2KH5Z@204458,2UG39@28211,COG3735@1,COG3735@2 NA|NA|NA S PFAM GumN family protein MAG.T12.39_02507 450851.PHZ_c2571 9.7e-156 556.6 Caulobacterales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MVPR@1224,2KFNJ@204458,2TRWZ@28211,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T12.39_02511 450851.PHZ_c1132 5.8e-171 607.8 Caulobacterales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1R1WX@1224,2KFVP@204458,2U0GK@28211,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug MAG.T12.39_02512 450851.PHZ_c1135 5.4e-78 297.7 Caulobacterales rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 ko00000,ko01000,ko03009 Bacteria 1MWGA@1224,2KG99@204458,2TU5K@28211,COG2961@1,COG2961@2 NA|NA|NA S Specifically methylates the adenine in position 2030 of 23S rRNA MAG.T12.39_02513 450851.PHZ_c1136 4.2e-66 257.7 Caulobacterales pglC ko:K13012 ko00000,ko01005 Bacteria 1MV6W@1224,2KFPR@204458,2TRZA@28211,COG2148@1,COG2148@2 NA|NA|NA GM PFAM sugar transferase MAG.T12.39_02514 1382303.JPOM01000001_gene442 8.2e-23 113.6 Caulobacterales cycP Bacteria 1Q594@1224,2KHII@204458,2UG98@28211,COG3909@1,COG3909@2 NA|NA|NA C Cytochrome C' MAG.T12.39_02515 450851.PHZ_c1139 1e-55 223.4 Caulobacterales cybP Bacteria 1RIG7@1224,2KK3R@204458,2U9DR@28211,COG3658@1,COG3658@2 NA|NA|NA C Prokaryotic cytochrome b561 MAG.T12.39_02517 450851.PHZ_c1140 3.8e-83 314.7 Alphaproteobacteria ko:K07107 ko00000,ko01000 Bacteria 1R6A6@1224,2TU6J@28211,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase MAG.T12.39_02518 450851.PHZ_c1141 1.6e-163 582.4 Caulobacterales lldD GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0004460,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0006004,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009060,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016898,GO:0017144,GO:0018130,GO:0019317,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019516,GO:0019637,GO:0019693,GO:0019752,GO:0032553,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042354,GO:0042355,GO:0042866,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0045333,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 R00196 RC00044 ko00000,ko00001,ko01000 iECOK1_1307.ECOK1_4049,iJN746.PP_4736 Bacteria 1MUEZ@1224,2KF0D@204458,2TQNW@28211,COG1304@1,COG1304@2 NA|NA|NA C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain MAG.T12.39_02519 1088721.NSU_1794 5.9e-121 441.4 Alphaproteobacteria Bacteria 1NVHG@1224,28PWR@1,2URVD@28211,2ZCGZ@2 NA|NA|NA MAG.T12.39_02520 1088721.NSU_1794 2.6e-85 322.4 Alphaproteobacteria Bacteria 1NVHG@1224,28PWR@1,2URVD@28211,2ZCGZ@2 NA|NA|NA MAG.T12.39_02521 450851.PHZ_c3246 4.4e-57 227.3 Caulobacterales MA20_35595 ko:K07068 ko00000 Bacteria 1PTPK@1224,2KJDN@204458,2VCIA@28211,COG1545@1,COG1545@2 NA|NA|NA S Rubredoxin-like zinc ribbon domain (DUF35_N) MAG.T12.39_02522 450851.PHZ_c3245 2.3e-202 711.4 Caulobacterales MA20_35590 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUZV@1224,2KH0C@204458,2TRHF@28211,COG0183@1,COG0183@2 NA|NA|NA I acetyl-coa acetyltransferase MAG.T12.39_02523 765911.Thivi_3670 7.2e-40 171.0 Chromatiales Bacteria 1RKQP@1224,1SB83@1236,1WYUH@135613,COG3900@1,COG3900@2 NA|NA|NA S Predicted periplasmic protein (DUF2092) MAG.T12.39_02525 59538.XP_005973954.1 2.8e-173 615.1 Cetartiodactyla Mammalia 3AIZB@33154,3BXNQ@33208,3DFMP@33213,3JP3T@40674,48SPA@7711,49P71@7742,4J1NF@91561,COG0318@1,KOG1176@2759 NA|NA|NA I 4-coumarate--CoA MAG.T12.39_02526 570268.ANBB01000089_gene770 2e-48 198.7 Streptosporangiales rraA ko:K02553 ko00000,ko03019 Bacteria 2IHQY@201174,4EJ50@85012,COG0684@1,COG0684@2 NA|NA|NA H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions MAG.T12.39_02528 114615.BRADO1150 4.7e-307 1061.2 Bradyrhizobiaceae ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 ko00000,ko00001,ko01000,ko02042,ko02048 Bacteria 1MWMG@1224,2TSE1@28211,3JSFJ@41294,COG0467@1,COG0467@2,COG1112@1,COG1112@2 NA|NA|NA L Protein of unknown function (DUF4011) MAG.T12.39_02529 1280946.HY29_10735 2.7e-22 112.8 Hyphomonadaceae Bacteria 1MY27@1224,2UWGZ@28211,43XZ8@69657,COG3134@1,COG3134@2 NA|NA|NA S Beta/gamma crystallins MAG.T12.39_02531 69395.JQLZ01000016_gene3972 4.3e-20 104.0 Caulobacterales secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1N75P@1224,2KH7G@204458,2UF51@28211,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation MAG.T12.39_02532 450851.PHZ_c1212 1.4e-88 332.4 Caulobacterales nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1MU14@1224,2KF1J@204458,2TRID@28211,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination MAG.T12.39_02533 1229204.AMYY01000042_gene1974 8.8e-64 249.6 unclassified Alphaproteobacteria rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RA2M@1224,2U760@28211,4BQ4R@82117,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors MAG.T12.39_02534 1449049.JONW01000002_gene2559 2.7e-99 368.2 Caulobacterales rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MUE6@1224,2KFS0@204458,2TRXP@28211,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release MAG.T12.39_02535 450851.PHZ_c2007 3e-194 684.5 Caulobacterales 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5G@1224,2KIG3@204458,2TQQ7@28211,COG0183@1,COG0183@2 NA|NA|NA I Thiolase, C-terminal domain MAG.T12.39_02536 450851.PHZ_c1216 1.1e-57 229.6 Caulobacterales rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RAN5@1224,2KG8X@204458,2U592@28211,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors MAG.T12.39_02537 59538.XP_005970156.1 1.9e-46 191.8 Eukaryota rpl12 GO:0000311,GO:0000313,GO:0000315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005911,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009506,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009547,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009735,GO:0009941,GO:0009987,GO:0010033,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0030054,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0034641,GO:0034645,GO:0042221,GO:0042651,GO:0042742,GO:0043043,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0055035,GO:0055044,GO:0071704,GO:0098542,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02863,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Eukaryota COG0222@1,KOG1715@2759 NA|NA|NA J structural constituent of ribosome MAG.T12.39_02538 1449049.JONW01000005_gene1788 5.7e-71 275.0 Alphaproteobacteria Bacteria 1RB35@1224,2U2A3@28211,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T12.39_02541 395964.KE386496_gene165 7.5e-41 173.3 Beijerinckiaceae ko:K07032 ko00000 Bacteria 1N116@1224,2VAK0@28211,3NCTB@45404,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T12.39_02542 509190.Cseg_0222 1.6e-34 153.7 Bacteria ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria COG0810@1,COG0810@2 NA|NA|NA M energy transducer activity MAG.T12.39_02543 1280949.HAD_16172 1.5e-66 260.0 Hyphomonadaceae Bacteria 1MVF0@1224,2TTR7@28211,43WGA@69657,COG2141@1,COG2141@2 NA|NA|NA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases MAG.T12.39_02544 450851.PHZ_c0889 7.2e-40 170.2 Caulobacterales Bacteria 1N088@1224,2KH05@204458,2UEDK@28211,COG2050@1,COG2050@2 NA|NA|NA Q thioesterase MAG.T12.39_02545 316055.RPE_1775 9.3e-19 99.4 Alphaproteobacteria Bacteria 1N8EP@1224,2UH48@28211,COG5304@1,COG5304@2 NA|NA|NA S CopG antitoxin of type II toxin-antitoxin system MAG.T12.39_02546 1502851.FG93_03221 2.5e-49 201.4 Bradyrhizobiaceae Bacteria 1N0J5@1224,2UDVP@28211,3K4GE@41294,COG3744@1,COG3744@2 NA|NA|NA S PIN domain MAG.T12.39_02547 745310.G432_18690 6.3e-24 116.3 Sphingomonadales Bacteria 1NH4W@1224,2K89P@204457,2VGVM@28211,COG4118@1,COG4118@2 NA|NA|NA D Antitoxin Phd_YefM, type II toxin-antitoxin system MAG.T12.39_02548 450851.PHZ_c0594 3.1e-12 77.0 Caulobacterales Bacteria 1R76Q@1224,2KG8Z@204458,2U3G8@28211,COG2124@1,COG2124@2 NA|NA|NA C cytochrome P450 MAG.T12.39_02549 59538.XP_005967196.1 5.4e-302 1043.1 Cetartiodactyla Mammalia 38B8B@33154,3BG4D@33208,3CXK5@33213,3J4DW@40674,484SM@7711,48VMD@7742,4J1FR@91561,COG0021@1,KOG0523@2759 NA|NA|NA G Transketolase MAG.T12.39_02551 190650.CC_3247 8.8e-32 142.9 Caulobacterales zapA ko:K09888 ko00000,ko03036 Bacteria 1N8NY@1224,2KHAE@204458,2UCRX@28211,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division MAG.T12.39_02552 450851.PHZ_c3186 7.7e-34 150.2 Caulobacterales ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1MZG0@1224,2KH4H@204458,2UBY4@28211,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family MAG.T12.39_02553 366602.Caul_0776 1.2e-136 492.7 Caulobacterales ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1MW12@1224,2KFPT@204458,2TS4S@28211,COG1692@1,COG1692@2 NA|NA|NA S metallophosphoesterase MAG.T12.39_02554 190650.CC_1180 9.3e-30 137.1 Caulobacterales Bacteria 1NEU4@1224,2E5AF@1,2KH9P@204458,2UI3N@28211,3302M@2 NA|NA|NA S EF hand MAG.T12.39_02555 450851.PHZ_c3183 2.1e-18 98.6 Caulobacterales yvlD ko:K08972 ko00000 Bacteria 1N1DF@1224,2KGZA@204458,2UDEK@28211,COG1950@1,COG1950@2 NA|NA|NA S PFAM Membrane protein of MAG.T12.39_02556 450851.PHZ_c3182 4.8e-116 424.1 Caulobacterales groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1MURR@1224,2KFR3@204458,2TS07@28211,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T12.39_02557 1121385.AQXW01000004_gene2053 2.3e-73 281.6 Dermacoccaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1ZVJ3@145357,2GMVW@201174,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA MAG.T12.39_02558 1048339.KB913029_gene2745 7.7e-56 223.0 Frankiales rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHUF@201174,4ESMM@85013,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit MAG.T12.39_02559 450851.PHZ_c1221 2.2e-30 138.3 Caulobacterales ko:K09981 ko00000 Bacteria 1N6ZY@1224,2KHBV@204458,2UFVY@28211,COG3809@1,COG3809@2 NA|NA|NA S Transcription factor zinc-finger MAG.T12.39_02560 450851.PHZ_c1219 1.6e-278 964.9 Caulobacterales rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1MU3M@1224,2KEZV@204458,2TRHV@28211,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T12.39_02561 450851.PHZ_c0891 1.2e-17 95.5 Caulobacterales Bacteria 1R3AV@1224,2E30U@1,2KH8X@204458,2TZZY@28211,32Y1A@2 NA|NA|NA S Protein of unknown function (DUF3253) MAG.T12.39_02562 450851.PHZ_c0890 3.6e-189 667.5 Caulobacterales fadE ko:K06446 ko00930,ko01100,ko01120,map00930,map01100,map01120 R06943 RC00052 ko00000,ko00001,ko01000 Bacteria 1MUDR@1224,2KF6Z@204458,2TQKE@28211,COG1960@1,COG1960@2 NA|NA|NA C acyl-CoA dehydrogenase MAG.T12.39_02563 366602.Caul_0020 1.1e-167 596.3 Caulobacterales MA20_04500 Bacteria 1MV8Q@1224,2KHW8@204458,2TRWW@28211,COG2124@1,COG2124@2 NA|NA|NA C cytochrome P450 MAG.T12.39_02564 59538.XP_005967471.1 5.4e-225 786.9 Cetartiodactyla Mammalia 38CAC@33154,3B9FF@33208,3CS9A@33213,3JBZ5@40674,4804V@7711,497Y0@7742,4IXTJ@91561,COG0458@1,KOG0370@2759 NA|NA|NA F Carbamoyl-phosphate synthase MAG.T12.39_02566 1125973.JNLC01000013_gene3821 1.6e-32 144.8 Bradyrhizobiaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUQI@1224,2TQM7@28211,3JV56@41294,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T12.39_02567 450851.PHZ_c0781 1.2e-127 463.0 Caulobacterales ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 iYL1228.KPN_03597,ic_1306.c3945 Bacteria 1MUK6@1224,2KFM3@204458,2TSDZ@28211,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T12.39_02568 450851.PHZ_c0780 2.1e-87 328.9 Caulobacterales 2.1.1.223 ko:K15460 ko00000,ko01000,ko03016 Bacteria 1MXEQ@1224,2KG70@204458,2TUBR@28211,COG4123@1,COG4123@2 NA|NA|NA S Methyltransferase MAG.T12.39_02569 246200.SPO0482 4.1e-39 167.2 Ruegeria MA20_30235 1.6.5.3 ko:K00329 ko00190,map00190 R11945 RC00061 ko00000,ko00001,ko01000 Bacteria 1MZK8@1224,2C7TH@1,2UC2R@28211,32RJS@2,4NCCK@97050 NA|NA|NA S ETC complex I subunit conserved region MAG.T12.39_02570 391624.OIHEL45_11188 6.4e-07 61.2 Proteobacteria Bacteria 1N6X0@1224,COG1873@1,COG1873@2 NA|NA|NA S PFAM PRC-barrel domain protein MAG.T12.39_02572 1042326.AZNV01000064_gene5704 6.7e-08 62.8 Rhizobiaceae Bacteria 1PSFP@1224,2DHXC@1,2V4MN@28211,3019X@2,4BKMX@82115 NA|NA|NA MAG.T12.39_02573 316056.RPC_0725 3e-39 167.9 Bradyrhizobiaceae Bacteria 1MXYX@1224,2TQR3@28211,3JX47@41294,COG3677@1,COG3677@2 NA|NA|NA L ISXO2-like transposase domain MAG.T12.39_02577 935848.JAEN01000008_gene624 3.8e-62 244.2 Paracoccus matB ko:K18661 ko00280,map00280 R03383 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MU6G@1224,2PUAF@265,2TR2W@28211,COG0318@1,COG0318@2 NA|NA|NA IQ Catalyzes the formation of malonyl-CoA from malonate and CoA MAG.T12.39_02578 1121861.KB899946_gene3939 2.6e-62 245.0 Rhodospirillales adhA 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MUTT@1224,2JR9U@204441,2TTI9@28211,COG1064@1,COG1064@2 NA|NA|NA S Alcohol dehydrogenase GroES-like domain MAG.T12.39_02579 1123072.AUDH01000019_gene2239 3.1e-34 151.4 Rhodospirillales ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1MWHZ@1224,2JPNT@204441,2TRK6@28211,COG1622@1,COG1622@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T12.39_02581 349102.Rsph17025_0619 6.7e-33 146.7 Alphaproteobacteria surf-1 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 1MWWG@1224,2U0N5@28211,COG3346@1,COG3346@2 NA|NA|NA S Surf1-like protein MAG.T12.39_02582 1207058.L53_08540 3.1e-57 228.0 Hyphomonadaceae rkpK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW5U@1224,2TREV@28211,43WJH@69657,COG1004@1,COG1004@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T12.39_02583 1121123.AUAO01000002_gene33 3.1e-42 177.6 Caulobacterales ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MUH9@1224,2KFPD@204458,2TR1C@28211,COG0226@1,COG0226@2 NA|NA|NA P PBP superfamily domain # 2384 queries scanned # Total time (seconds): 55.3734579086 # Rate: 43.05 q/s