# emapper version: emapper-2.0.1 emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 45 --temp_dir /media/bayegy/disk0/binning_test/Bin_all/emapper//bin.T13.38/_tmp -i /media/bayegy/disk0/binning_test/Bin_all/Bin_prokka//bin.T13.38/bin.T13.38.faa -o /media/bayegy/disk0/binning_test/Bin_all/emapper//bin.T13.38/bin.T13.38 --usemem --override # time: Wed Nov 3 17:49:48 2021 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. OINAGBCE_00002 1541065.JRFE01000050_gene2947 2e-30 139.0 Pleurocapsales 2.3.1.189 ko:K15520 ko00000,ko01000 Bacteria 1GCIE@1117,3VKF6@52604,COG0454@1,COG0456@2 NA|NA|NA K PFAM Acetyltransferase (GNAT) family OINAGBCE_00003 765952.PUV_04360 3.6e-15 87.4 Bacteria Bacteria COG4453@1,COG4453@2 NA|NA|NA K Protein conserved in bacteria OINAGBCE_00004 760117.JN27_12635 5.5e-35 154.5 Oxalobacteraceae kynB GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1P8U5@1224,2VHG4@28216,4763J@75682,COG1878@1,COG1878@2 NA|NA|NA S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation OINAGBCE_00005 765952.PUV_00690 2.4e-273 948.0 Chlamydiae uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2JFI1@204428,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage OINAGBCE_00006 221288.JH992901_gene3283 9.9e-19 99.4 Stigonemataceae ko:K07075 ko00000 Bacteria 1G7R5@1117,1JMB5@1189,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain OINAGBCE_00007 313624.NSP_16690 5.4e-29 133.7 Nostocales Bacteria 1G7TP@1117,1HNW6@1161,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 OINAGBCE_00009 765952.PUV_00700 1.7e-140 505.8 Chlamydiae trpS 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFCD@204428,COG0180@1,COG0180@2 NA|NA|NA J Tryptophanyl-tRNA synthetase OINAGBCE_00010 1437425.CSEC_1514 5.1e-93 348.2 Chlamydiae ko:K03834 ko00000,ko02000 2.A.42.1.1 Bacteria 2JFWY@204428,COG0814@1,COG0814@2 NA|NA|NA E Tryptophan/tyrosine permease family OINAGBCE_00011 264201.pc0168 7e-76 291.2 Chlamydiae tyrP_1 ko:K03834 ko00000,ko02000 2.A.42.1.1 Bacteria 2JFFY@204428,COG0814@1,COG0814@2 NA|NA|NA E Tryptophan/tyrosine permease family OINAGBCE_00012 765952.PUV_02000 1e-221 776.2 Chlamydiae thyX 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 R06613 RC00022,RC00332 ko00000,ko00001,ko01000 Bacteria 2JFK7@204428,COG1351@1,COG1351@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant OINAGBCE_00013 765952.PUV_24260 9.7e-22 110.9 Chlamydiae CP_1102 Bacteria 2AUH6@1,2JHI8@204428,33DD5@2 NA|NA|NA OINAGBCE_00014 485915.Dret_0957 1.1e-23 116.3 Desulfovibrionales osmE GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 ko:K04064,ko:K06186 ko00000,ko02000 1.B.33.1 Bacteria 1N2JT@1224,2MCG6@213115,2WW64@28221,42UGE@68525,COG2913@1,COG2913@2 NA|NA|NA J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane OINAGBCE_00015 485915.Dret_0956 4.5e-11 74.7 Desulfovibrionales Bacteria 1RIQF@1224,2ATAH@1,2MCSQ@213115,2WVXW@28221,31ITJ@2,42THB@68525 NA|NA|NA OINAGBCE_00018 331113.SNE_A02540 3.5e-128 465.3 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_00020 331113.SNE_A00770 6e-31 141.0 Chlamydiae Bacteria 2EQNW@1,2JGJ8@204428,33I8U@2 NA|NA|NA OINAGBCE_00021 331113.SNE_A00760 9.2e-43 180.6 Chlamydiae Bacteria 2JFH5@204428,COG1196@1,COG1196@2,COG3209@1,COG3209@2 NA|NA|NA M Rhs family OINAGBCE_00023 522306.CAP2UW1_1981 5.5e-29 135.6 Betaproteobacteria Bacteria 1MWX5@1224,2VHU4@28216,COG1538@1,COG1538@2 NA|NA|NA MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) OINAGBCE_00024 1121918.ARWE01000001_gene3024 3.3e-43 182.6 Desulfuromonadales mdtA ko:K07799,ko:K21135 ko02020,map02020 M00648,M00822 ko00000,ko00001,ko00002,ko02000 2.A.6.2.35,8.A.1 Bacteria 1MW65@1224,2WJ8R@28221,42NJG@68525,43US6@69541,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like OINAGBCE_00025 1444711.CCJF01000004_gene1917 1.2e-188 667.2 Chlamydiae mdtB ko:K03296 ko00000 2.A.6.2 Bacteria 2JFXK@204428,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family OINAGBCE_00027 99598.Cal7507_4615 7.9e-36 158.3 Nostocales ko:K06900 ko00000 Bacteria 1G2Q1@1117,1HJ4V@1161,COG3621@1,COG3621@2 NA|NA|NA S Patatin-like phospholipase OINAGBCE_00028 716544.wcw_1141 9.2e-60 236.9 Chlamydiae lolD ko:K02003,ko:K02004,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2JFYR@204428,COG1136@1,COG1136@2 NA|NA|NA V system ATP-binding protein LolD OINAGBCE_00029 716544.wcw_1140 1.8e-50 206.1 Chlamydiae lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 2JHHC@204428,COG4591@1,COG4591@2 NA|NA|NA M FtsX-like permease family OINAGBCE_00030 1444711.CCJF01000004_gene2238 0.0 2296.9 Chlamydiae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2JFCX@204428,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates OINAGBCE_00032 933262.AXAM01000139_gene294 5.5e-133 481.5 Desulfobacterales Bacteria 1R7NE@1224,2MJVY@213118,2WKHV@28221,42M25@68525,COG5421@1,COG5421@2 NA|NA|NA L IMG reference gene OINAGBCE_00033 1437425.CSEC_2098 7.7e-32 145.6 Bacteria 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria COG2366@1,COG2366@2 NA|NA|NA D antibiotic biosynthetic process OINAGBCE_00037 765952.PUV_25910 5.3e-73 280.8 Chlamydiae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFYD@204428,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate OINAGBCE_00038 765952.PUV_25920 5.7e-141 507.7 Chlamydiae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 2JFUE@204428,COG0486@1,COG0486@2 NA|NA|NA J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 OINAGBCE_00040 1444711.CCJF01000005_gene324 3.5e-86 325.1 Chlamydiae psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFMN@204428,COG0688@1,COG0688@2 NA|NA|NA I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) OINAGBCE_00042 1444711.CCJF01000005_gene400 1.6e-83 315.8 Chlamydiae ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFZR@204428,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine OINAGBCE_00043 1444711.CCJF01000005_gene634 7.5e-84 317.4 Chlamydiae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2JFHS@204428,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine OINAGBCE_00044 264201.pc2010 2.8e-12 78.6 Chlamydiae Bacteria 2E4EM@1,2JGDC@204428,32Z9U@2 NA|NA|NA OINAGBCE_00045 4533.OB03G36840.1 1.1e-06 62.4 Poales Viridiplantae 37HF2@33090,3G8J9@35493,3IDRJ@38820,3M296@4447,COG0666@1,KOG0504@2759 NA|NA|NA O Ankyrin repeats (3 copies) OINAGBCE_00047 244581.IM40_02900 1.2e-95 356.7 Rickettsiales hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MWMW@1224,2TS3F@28211,47EXD@766,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family OINAGBCE_00049 1444711.CCJF01000005_gene399 3e-51 208.8 Chlamydiae CP_1067 Bacteria 2CK4I@1,2JFZG@204428,2ZBXP@2 NA|NA|NA S Virulence plasmid protein pGP6-D-related protein OINAGBCE_00050 1444711.CCJF01000005_gene398 7.5e-98 363.6 Chlamydiae minD ko:K03496 ko00000,ko03036,ko04812 Bacteria 2JFK5@204428,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ OINAGBCE_00051 1444711.CCJF01000005_gene397 1.5e-264 918.7 Chlamydiae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFEP@204428,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) OINAGBCE_00052 264201.pc0003 6.8e-240 837.4 Chlamydiae CP_1081 Bacteria 2JFIZ@204428,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation OINAGBCE_00053 765952.PUV_27500 4e-83 315.5 Chlamydiae Bacteria 2BADF@1,2JG8B@204428,323TX@2 NA|NA|NA OINAGBCE_00054 103690.17134415 7.1e-29 133.3 Nostocales hicB Bacteria 1G90M@1117,1HU6K@1161,COG4226@1,COG4226@2 NA|NA|NA S HicB family OINAGBCE_00055 765952.PUV_09000 4.8e-85 321.2 Chlamydiae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2JFCQ@204428,COG4974@1,COG4974@2 NA|NA|NA D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids OINAGBCE_00056 331113.SNE_A10670 1.1e-31 144.1 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_00057 1444711.CCJF01000004_gene2420 2.3e-173 615.5 Chlamydiae pgi GO:0001701,GO:0001704,GO:0001707,GO:0002262,GO:0002376,GO:0002637,GO:0002639,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007369,GO:0007498,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009410,GO:0009435,GO:0009438,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010466,GO:0010594,GO:0010595,GO:0010605,GO:0010632,GO:0010634,GO:0010941,GO:0010951,GO:0014070,GO:0014072,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0016866,GO:0017144,GO:0018130,GO:0019222,GO:0019242,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030246,GO:0030334,GO:0030335,GO:0031090,GO:0031253,GO:0031323,GO:0031324,GO:0031625,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0032880,GO:0033500,GO:0033554,GO:0034101,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0040007,GO:0040012,GO:0040017,GO:0042180,GO:0042181,GO:0042221,GO:0042493,GO:0042592,GO:0042593,GO:0042802,GO:0042866,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043278,GO:0043279,GO:0043281,GO:0043436,GO:0043523,GO:0043524,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045861,GO:0046031,GO:0046034,GO:0046184,GO:0046185,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048029,GO:0048332,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048598,GO:0048646,GO:0048729,GO:0048856,GO:0048872,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051023,GO:0051024,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051156,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0051716,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060170,GO:0060255,GO:0060359,GO:0060548,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070887,GO:0071704,GO:0071944,GO:0072330,GO:0072347,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097458,GO:0098588,GO:0098590,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901214,GO:1901215,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1903530,GO:1903532,GO:1904951,GO:2000116,GO:2000117,GO:2000145,GO:2000147 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iEcSMS35_1347.EcSMS35_4486,iJN746.PP_1808 Bacteria 2JFI4@204428,COG0166@1,COG0166@2 NA|NA|NA F glucose-6-phosphate isomerase OINAGBCE_00058 1444711.CCJF01000004_gene2418 9.1e-61 240.4 Chlamydiae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2JG2D@204428,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA OINAGBCE_00059 716544.wcw_0724 1.5e-20 107.1 Chlamydiae Bacteria 2ED9E@1,2JGFV@204428,3375V@2 NA|NA|NA OINAGBCE_00061 1444712.BN1013_01664 9.1e-200 703.7 Chlamydiae ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2JFN4@204428,COG1674@1,COG1674@2 NA|NA|NA D Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity) OINAGBCE_00063 765952.PUV_24550 2.3e-94 352.1 Chlamydiae yycJ Bacteria 2JFDF@204428,COG1235@1,COG1235@2 NA|NA|NA S Metallo-beta-lactamase superfamily OINAGBCE_00067 467661.RKLH11_3931 1.6e-111 409.5 Alphaproteobacteria mvaA 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1Q6M1@1224,2U1F3@28211,COG1257@1,COG1257@2 NA|NA|NA I COG1257 Hydroxymethylglutaryl-CoA reductase OINAGBCE_00069 1356854.N007_09270 2.8e-07 60.8 Bacteria CP_0775 ko:K09779 ko00000 Bacteria COG2155@1,COG2155@2 NA|NA|NA S Domain of unknown function (DUF378) OINAGBCE_00071 1444712.BN1013_01250 3.7e-32 145.6 Chlamydiae Bacteria 2DUU3@1,2JGYS@204428,33S9I@2 NA|NA|NA OINAGBCE_00072 1444711.CCJF01000004_gene2439 2.5e-87 329.7 Chlamydiae recN ko:K03631,ko:K07459 ko00000,ko03400 Bacteria 2JFIH@204428,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA OINAGBCE_00073 765952.PUV_18230 5.8e-89 334.3 Chlamydiae rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2JFW4@204428,COG1039@1,COG1039@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids OINAGBCE_00074 1444712.BN1013_01254 1.9e-39 168.7 Chlamydiae yfgA Bacteria 2JG6D@204428,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain OINAGBCE_00075 1444711.CCJF01000004_gene2443 1e-51 210.7 Chlamydiae ko:K08974 ko00000 Bacteria 2JG06@204428,COG2035@1,COG2035@2 NA|NA|NA S Domain of unknown function (DUF368) OINAGBCE_00077 1444711.CCJF01000004_gene2444 3.6e-63 248.4 Chlamydiae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2JG1S@204428,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs OINAGBCE_00078 765952.PUV_18190 6.6e-46 190.7 Chlamydiae yhgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 2JG4G@204428,COG2095@1,COG2095@2 NA|NA|NA U UPF0056 inner membrane protein OINAGBCE_00079 1444711.CCJF01000004_gene2446 1e-46 193.4 Chlamydiae yhgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 2JGSC@204428,COG2095@1,COG2095@2 NA|NA|NA U MarC family integral membrane protein OINAGBCE_00081 1444711.CCJF01000004_gene2449 3.5e-118 431.8 Chlamydiae dapL GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2JFN7@204428,COG0436@1,COG0436@2 NA|NA|NA E Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate OINAGBCE_00082 1444711.CCJF01000004_gene2450 1.1e-68 266.9 Chlamydiae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFTE@204428,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) OINAGBCE_00083 1444711.CCJF01000004_gene2451 1.1e-48 200.3 Chlamydiae dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1520 Bacteria 2JG1F@204428,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate OINAGBCE_00084 1444711.CCJF01000004_gene2452 3e-57 229.2 Chlamydiae CP_0428 Bacteria 2JG2C@204428,COG1502@1,COG1502@2 NA|NA|NA I Phospholipase D family protein OINAGBCE_00085 477974.Daud_0168 1.5e-178 632.9 Peptococcaceae ubiD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.61,4.1.1.98 ko:K03182,ko:K16239 ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120 M00117 R01238,R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_4669 Bacteria 1TQ6V@1239,248WY@186801,261BW@186807,COG0043@1,COG0043@2 NA|NA|NA H Belongs to the UbiD family OINAGBCE_00086 1444711.CCJF01000005_gene1759 1.6e-26 125.2 Chlamydiae rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGBN@204428,COG0227@1,COG0227@2 NA|NA|NA J Ribosomal L28 family OINAGBCE_00089 765952.PUV_03080 2.2e-133 481.9 Chlamydiae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 2JFIS@204428,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA OINAGBCE_00090 1444712.BN1013_00024 2.8e-33 148.7 Bacteria rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria COG0127@1,COG0127@2 NA|NA|NA F nucleoside triphosphate catabolic process OINAGBCE_00091 264201.pc1262 6.5e-177 627.5 Chlamydiae pmmB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFUP@204428,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase OINAGBCE_00098 1125863.JAFN01000001_gene2394 2.5e-22 111.7 Deltaproteobacteria vapC Bacteria 1N96B@1224,2WR0Y@28221,42TZ7@68525,COG4113@1,COG4113@2 NA|NA|NA S PIN domain OINAGBCE_00100 1123508.JH636447_gene7985 2.5e-29 136.7 Planctomycetes crtF 2.1.1.210 ko:K09846 ko00906,ko01100,map00906,map01100 R07521,R07524,R07527,R07529,R07533,R07535 RC00003,RC02082 ko00000,ko00001,ko01000 Bacteria 2IXEP@203682,COG0500@1,COG2226@2 NA|NA|NA Q O-methyltransferase OINAGBCE_00101 765952.PUV_18090 6.5e-74 284.3 Chlamydiae Bacteria 2JH19@204428,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain OINAGBCE_00103 1444712.BN1013_00850 9.4e-31 140.2 Bacteria 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria COG0494@1,COG0494@2 NA|NA|NA L nUDIX hydrolase OINAGBCE_00104 765952.PUV_22070 6.4e-257 894.0 Chlamydiae Bacteria 2JFQ8@204428,COG0457@1,COG0457@2,COG0515@1,COG0515@2 NA|NA|NA F Together with the serine threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth OINAGBCE_00105 765952.PUV_20420 0.0 2222.6 Chlamydiae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2JFSD@204428,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate OINAGBCE_00106 215803.DB30_5068 2e-76 293.1 Myxococcales Bacteria 1QTX0@1224,2WKPN@28221,2Z26U@29,42QJX@68525,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily OINAGBCE_00107 483219.LILAB_16730 2.5e-72 279.3 Myxococcales Bacteria 1MU7P@1224,2WIQD@28221,2YUVF@29,42NQP@68525,COG0123@1,COG0123@2 NA|NA|NA BQ Histone deacetylase domain OINAGBCE_00108 1192034.CAP_6183 1.9e-39 169.5 Deltaproteobacteria Bacteria 1P379@1224,2FDVK@1,2WWV3@28221,345W5@2,4314K@68525 NA|NA|NA OINAGBCE_00110 1192034.CAP_6182 1.6e-87 329.7 Myxococcales epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 ko:K04568 ko00000,ko01000,ko03012 Bacteria 1MU97@1224,2WJBB@28221,2YUT5@29,42MAN@68525,COG2269@1,COG2269@2 NA|NA|NA J tRNA synthetases class II (D, K and N) OINAGBCE_00111 264201.pc1225 6.5e-235 820.5 Chlamydiae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFSI@204428,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA OINAGBCE_00114 765952.PUV_20510 1.2e-240 839.7 Chlamydiae mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 Bacteria 2JFCU@204428,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity OINAGBCE_00115 1122164.JHWF01000017_gene549 2.4e-09 68.6 Legionellales Bacteria 1JGNQ@118969,1NNFU@1224,1SSRJ@1236,2ENBK@1,33FZ7@2 NA|NA|NA OINAGBCE_00118 331113.SNE_A06460 7.7e-89 334.3 Chlamydiae proP4 ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2JGYM@204428,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter OINAGBCE_00120 331113.SNE_A00120 2.8e-14 84.3 Bacteria ko:K07726 ko00000,ko03000 Bacteria COG2944@1,COG2944@2 NA|NA|NA K sequence-specific DNA binding OINAGBCE_00121 1442598.JABW01000024_gene1553 2.3e-136 492.7 delta/epsilon subdivisions 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1PF1D@1224,42Y7A@68525,COG1846@1,COG1846@2,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal OINAGBCE_00122 765952.PUV_24360 4.9e-153 547.7 Chlamydiae uhpC GO:0000160,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K02445,ko:K07783 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.4.3,2.A.1.4.4,2.A.1.4.6 Bacteria 2JFUY@204428,COG2271@1,COG2271@2 NA|NA|NA G Hexose phosphate transport protein OINAGBCE_00123 264201.pc1998 3.5e-75 288.9 Chlamydiae 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 2JGUU@204428,COG2265@1,COG2265@2 NA|NA|NA J tRNA (Uracil-5-)-methyltransferase OINAGBCE_00124 1444711.CCJF01000005_gene440 1.4e-50 206.5 Chlamydiae 2.7.7.13,5.4.2.8 ko:K00966,ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2JHHK@204428,COG1208@1,COG1208@2 NA|NA|NA JM Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits OINAGBCE_00125 1444711.CCJF01000005_gene441 2.2e-61 242.7 Chlamydiae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2JFYA@204428,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family OINAGBCE_00126 1444711.CCJF01000005_gene1168 6.4e-248 863.6 Bacteria recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase (RecQ) OINAGBCE_00127 9402.XP_006908761.1 2.2e-31 143.3 Mammalia PTPN11 3.1.3.48 ko:K07293 ko04013,ko04014,ko04072,ko04360,ko04630,ko04650,ko04670,ko04722,ko04920,ko04931,ko05120,ko05168,ko05205,ko05211,ko05220,map04013,map04014,map04072,map04360,map04630,map04650,map04670,map04722,map04920,map04931,map05120,map05168,map05205,map05211,map05220 ko00000,ko00001,ko01000,ko01009 Mammalia 39S7A@33154,3BCJ0@33208,3CUJE@33213,3J545@40674,48269@7711,490ME@7742,COG5599@1,KOG0790@2759 NA|NA|NA T negative regulation of cortisol secretion OINAGBCE_00128 1444711.CCJF01000005_gene442 2.9e-148 531.6 Chlamydiae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2JFVU@204428,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage OINAGBCE_00129 264201.pc1991 8.7e-86 324.3 Chlamydiae CP_1108 Bacteria 2JFW2@204428,COG2849@1,COG2849@2 NA|NA|NA S MORN repeat variant OINAGBCE_00130 1444711.CCJF01000005_gene446 3.4e-32 145.2 Chlamydiae Bacteria 28PTN@1,2JFZY@204428,2ZCEV@2 NA|NA|NA OINAGBCE_00131 1444712.BN1013_00355 6.9e-66 258.5 Chlamydiae ko:K02662 ko00000,ko02035,ko02044 Bacteria 2JFIK@204428,COG4972@1,COG4972@2 NA|NA|NA NU Pilus assembly protein OINAGBCE_00132 716544.wcw_1973 5.6e-18 96.7 Chlamydiae ylmG ko:K02221 ko00000,ko02044 Bacteria 2JGD3@204428,COG0762@1,COG0762@2 NA|NA|NA S YGGT family OINAGBCE_00133 1444711.CCJF01000005_gene449 2.3e-120 438.7 Chlamydiae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 2JFI0@204428,COG0042@1,COG0042@2 NA|NA|NA H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines OINAGBCE_00135 264201.pc0787 1.8e-19 103.2 Chlamydiae Bacteria 2JG31@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_00136 1220589.CD32_11785 9.1e-113 414.1 Lysinibacillus yflS ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3J064@400634,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region OINAGBCE_00138 1444711.CCJF01000005_gene565 3.5e-96 358.6 Chlamydiae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 2JFKQ@204428,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit OINAGBCE_00139 765952.PUV_27350 3.1e-48 198.7 Chlamydiae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2JG2I@204428,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family OINAGBCE_00140 716544.wcw_1867 1.4e-82 313.5 Chlamydiae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2JFKF@204428,COG0617@1,COG0617@2 NA|NA|NA H polymerase OINAGBCE_00141 765952.PUV_03700 1e-102 380.9 Chlamydiae mutL GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 2.1.1.37 ko:K00558,ko:K03572 ko00270,ko01100,ko03430,ko05206,map00270,map01100,map03430,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2JFM7@204428,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex OINAGBCE_00142 765952.PUV_03690 1e-76 293.9 Chlamydiae pepP 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2JFYS@204428,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain OINAGBCE_00143 765952.PUV_01190 9.6e-51 207.6 Chlamydiae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 2JG1B@204428,COG1792@1,COG1792@2 NA|NA|NA M rod shape-determining protein MreC OINAGBCE_00144 1444711.CCJF01000005_gene490 5.3e-79 301.6 Chlamydiae tyrB GO:0003674,GO:0003824,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0008793,GO:0009058,GO:0009066,GO:0009067,GO:0009072,GO:0009073,GO:0009081,GO:0009082,GO:0009094,GO:0009095,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019292,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050048,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iECED1_1282.ECED1_4768,iECSE_1348.ECSE_4347,iJN746.PP_3590,iLF82_1304.LF82_2339,iNRG857_1313.NRG857_20250,iUTI89_1310.UTI89_C4629 Bacteria 2JFQ5@204428,COG1448@1,COG1448@2 NA|NA|NA E Aminotransferase OINAGBCE_00146 1444711.CCJF01000005_gene614 1.1e-175 623.6 Chlamydiae dinG GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 2JFNF@204428,COG1199@1,COG1199@2 NA|NA|NA L helicase dinG OINAGBCE_00147 1444711.CCJF01000005_gene615 3.9e-253 880.6 Chlamydiae rpoD ko:K03086 ko00000,ko03021 Bacteria 2JFP5@204428,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth OINAGBCE_00148 716544.wcw_1948 1e-33 150.6 Chlamydiae coiA ko:K06198 ko00000 Bacteria 2JG50@204428,COG4469@1,COG4469@2 NA|NA|NA S Competence protein CoiA-like family OINAGBCE_00150 1444712.BN1013_00290 5.3e-12 77.0 Chlamydiae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGDY@204428,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA OINAGBCE_00151 716544.wcw_1940 2e-80 306.2 Chlamydiae mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1,2.7.3.2,2.7.3.3 ko:K00933,ko:K00934,ko:K19405 ko00330,ko01100,map00330,map01100 M00047 R00554,R01881,R11090 RC00002,RC00203 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JFHC@204428,COG3869@1,COG3869@2 NA|NA|NA F Catalyzes the specific phosphorylation of arginine residues in proteins OINAGBCE_00152 1444711.CCJF01000005_gene247 5.4e-39 167.5 Chlamydiae mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 2JG5I@204428,COG3880@1,COG3880@2 NA|NA|NA S UvrB/uvrC motif OINAGBCE_00153 1444712.BN1013_00289 2e-64 252.7 Chlamydiae rluD 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 Bacteria 2JFZK@204428,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil OINAGBCE_00154 264201.pc0143 1.7e-155 555.8 Chlamydiae eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2JFH6@204428,COG0148@1,COG0148@2 NA|NA|NA F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis OINAGBCE_00155 1437425.CSEC_1712 2.7e-30 138.3 Chlamydiae Bacteria 2CTCU@1,2JGAE@204428,32ST6@2 NA|NA|NA OINAGBCE_00156 765952.PUV_27440 2.6e-74 285.0 Chlamydiae ahpC 1.11.1.15 ko:K03386,ko:K20011 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2JFNN@204428,COG0450@1,COG0450@2 NA|NA|NA O Antioxidant, AhpC Tsa family OINAGBCE_00158 716544.wcw_1855 4.3e-50 205.7 Chlamydiae trkA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 ko:K03281,ko:K03499,ko:K05571 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49,2.A.63.1,2.A.63.2 iE2348C_1286.E2348C_3552 Bacteria 2JFU5@204428,COG0569@1,COG0569@2 NA|NA|NA C TrkA-C domain OINAGBCE_00159 765952.PUV_02070 2e-223 781.9 Chlamydiae groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0022610,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0050789,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2JFPP@204428,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions OINAGBCE_00160 716544.wcw_1848 4e-28 130.6 Chlamydiae groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2JG9S@204428,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter OINAGBCE_00161 765952.PUV_01490 2e-129 469.2 Chlamydiae ybbC Bacteria 2JFQB@204428,COG3876@1,COG3876@2 NA|NA|NA S Protein of unknown function (DUF1343) OINAGBCE_00162 1437425.CSEC_1417 4.1e-98 364.8 Bacteria hipA_1 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria COG3550@1,COG3550@2 NA|NA|NA S kinase activity OINAGBCE_00163 658187.LDG_6903 1.4e-26 125.6 Legionellales 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1JES5@118969,1NAM8@1224,1SD9R@1236,COG3550@1,COG3550@2 NA|NA|NA S HipA N-terminal domain OINAGBCE_00164 1122165.AUHS01000011_gene2592 8.3e-13 79.3 Legionellales ko:K07729 ko00000,ko03000 Bacteria 1JF45@118969,1P625@1224,1T7A7@1236,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain OINAGBCE_00165 80884.CCF45643 2.2e-09 70.5 Glomerellales IKS1 GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 ko:K08286 ko00000,ko01000 Fungi 1EZ6J@1028384,213Y9@147550,39FYR@33154,3NXZF@4751,3QKF9@4890,KOG0032@1,KOG0032@2759 NA|NA|NA T Calcium-dependent protein kinase OINAGBCE_00169 264201.pc1261 7.5e-45 186.8 Chlamydiae ko:K06940 ko00000 Bacteria 2JG8E@204428,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain OINAGBCE_00170 1444711.CCJF01000005_gene1528 1.5e-31 142.9 Chlamydiae MA20_30435 Bacteria 2JGET@204428,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) OINAGBCE_00172 331113.SNE_A05240 3.1e-125 455.3 Bacteria Bacteria COG2271@1,COG2271@2 NA|NA|NA G transmembrane transporter activity OINAGBCE_00173 331113.SNE_A05230 3.1e-72 278.1 Chlamydiae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 2JGIN@204428,COG1435@1,COG1435@2 NA|NA|NA F Thymidine kinase OINAGBCE_00175 1444712.BN1013_01116 2.3e-111 409.5 Chlamydiae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFHH@204428,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides OINAGBCE_00176 1444711.CCJF01000005_gene1380 2.7e-17 94.4 Chlamydiae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2JGDI@204428,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides OINAGBCE_00177 765952.PUV_10140 3.4e-72 278.5 Chlamydiae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 2JFSA@204428,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP OINAGBCE_00179 264201.pc0787 1.2e-10 73.9 Chlamydiae Bacteria 2JG31@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_00181 126957.SMAR013115-PA 1.7e-09 70.5 Arthropoda GO:0001700,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0009790,GO:0009792,GO:0009966,GO:0009968,GO:0009987,GO:0010453,GO:0010454,GO:0010646,GO:0010648,GO:0010721,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0022008,GO:0022603,GO:0023051,GO:0023057,GO:0030029,GO:0030036,GO:0030154,GO:0032501,GO:0032502,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045177,GO:0045501,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045676,GO:0045677,GO:0045873,GO:0046532,GO:0046533,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051239,GO:0051241,GO:0051960,GO:0051961,GO:0060284,GO:0065007,GO:0071704,GO:0071840,GO:0097435,GO:0140096,GO:1901564,GO:2000026,GO:2000027 2.7.12.1 ko:K08287,ko:K08841,ko:K08842 ko00000,ko01000,ko01001 Arthropoda 2QTCP@2759,38BED@33154,3BCNJ@33208,3CX11@33213,41W2S@6656,COG0515@1 NA|NA|NA T ATP binding. It is involved in the biological process described with protein phosphorylation OINAGBCE_00182 1444711.CCJF01000005_gene900 5e-53 214.5 Chlamydiae ycjU 5.4.2.6 ko:K01838 ko00500,map00500 R02728,R11310 RC00408 ko00000,ko00001,ko01000 Bacteria 2JG4C@204428,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase OINAGBCE_00183 716544.wcw_0372 1.6e-68 266.2 Chlamydiae ycbK 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 2JG29@204428,COG3108@1,COG3108@2 NA|NA|NA S Peptidase M15 OINAGBCE_00186 234267.Acid_3421 2.1e-43 183.0 Acidobacteria ykfC Bacteria 3Y5IG@57723,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family OINAGBCE_00187 765952.PUV_25400 1.6e-23 116.3 Chlamydiae ko:K07117 ko00000 Bacteria 2JG8R@204428,COG2940@1,COG2940@2 NA|NA|NA S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain OINAGBCE_00188 1444711.CCJF01000005_gene1567 2.2e-96 359.8 Chlamydiae Bacteria 2B54A@1,2JFT9@204428,31A9I@2 NA|NA|NA OINAGBCE_00191 765952.PUV_05130 3.2e-19 102.1 Chlamydiae Bacteria 2JG48@204428,COG0457@1,COG0457@2 NA|NA|NA S Type III secretion chaperone SycD OINAGBCE_00192 264201.pc0322 5.8e-266 923.3 Chlamydiae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2JFFF@204428,COG0481@1,COG0481@2 NA|NA|NA J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner OINAGBCE_00193 1437425.CSEC_1855 2.6e-66 258.8 Chlamydiae uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 iLJ478.TM1398 Bacteria 2JFZ2@204428,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids OINAGBCE_00194 1444711.CCJF01000005_gene885 3.4e-51 208.8 Chlamydiae cdsA 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2JHI7@204428,COG4589@1,COG4589@2 NA|NA|NA S Cytidylyltransferase family OINAGBCE_00195 1437425.CSEC_1857 1.1e-60 240.0 Chlamydiae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 2JFEA@204428,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily OINAGBCE_00197 1444711.CCJF01000005_gene882 2.9e-196 691.4 Chlamydiae gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFPS@204428,COG0362@1,COG0362@2 NA|NA|NA G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH OINAGBCE_00198 1437425.CSEC_0420 1.3e-15 90.1 Chlamydiae 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2JGK1@204428,COG0406@1,COG0406@2 NA|NA|NA G alpha-ribazole phosphatase activity OINAGBCE_00200 1485545.JQLW01000006_gene379 7.7e-14 82.8 Proteobacteria ko:K19156 ko00000,ko02048 Bacteria 1NAGM@1224,COG2002@1,COG2002@2 NA|NA|NA K prlF antitoxin for toxin YhaV_toxin OINAGBCE_00201 111780.Sta7437_3784 1.6e-26 125.6 Pleurocapsales ko:K07171 ko00000,ko01000,ko02048 Bacteria 1G8G1@1117,3VMR9@52604,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system OINAGBCE_00202 1341679.P253_02996 2.8e-13 80.9 Moraxellaceae ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1R9ZQ@1224,1RP9U@1236,3NKNQ@468,COG0652@1,COG0652@2 NA|NA|NA M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides OINAGBCE_00205 264201.pc1499 6.2e-266 923.3 Chlamydiae dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2JFEI@204428,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein OINAGBCE_00206 243161.TC_0674 1.5e-41 176.0 Chlamydiae grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 ko:K03687 ko00000,ko03029,ko03110 Bacteria 2JG6C@204428,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ OINAGBCE_00207 1444711.CCJF01000005_gene743 1.3e-96 360.1 Chlamydiae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 2JFK0@204428,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons OINAGBCE_00209 765952.PUV_06050 5.2e-139 501.1 Chlamydiae gdhB 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 R00243 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 2JFGR@204428,COG2902@1,COG2902@2 NA|NA|NA C Bacterial NAD-glutamate dehydrogenase OINAGBCE_00211 933262.AXAM01000014_gene229 6.1e-124 451.1 Proteobacteria ko:K07133 ko00000 Bacteria 1MWDX@1224,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily) OINAGBCE_00214 1444711.CCJF01000004_gene2038 6.7e-90 337.4 Chlamydiae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2JFEU@204428,COG4974@1,COG4974@2 NA|NA|NA D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids OINAGBCE_00215 264201.pc0442 1.3e-53 216.9 Chlamydiae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2JG16@204428,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine OINAGBCE_00216 264201.pc0443 2.8e-68 265.0 Chlamydiae clpP1 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFZF@204428,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins OINAGBCE_00217 1444711.CCJF01000004_gene2022 8.6e-191 673.3 Chlamydiae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFEM@204428,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism OINAGBCE_00219 1414720.CBYM010000003_gene388 1.4e-62 246.9 Clostridiaceae gacK 2.7.1.15,2.7.1.187,2.7.1.4,2.7.1.45 ko:K00847,ko:K00852,ko:K00874,ko:K19978 ko00030,ko00051,ko00500,ko00520,ko00525,ko01100,ko01120,ko01130,ko01200,map00030,map00051,map00500,map00520,map00525,map01100,map01120,map01130,map01200 M00061,M00308,M00631 R00760,R00867,R01051,R01541,R02750,R03920,R11184 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4QY@1239,24HRA@186801,36S3G@31979,COG0524@1,COG0524@2 NA|NA|NA G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway OINAGBCE_00220 1444711.CCJF01000004_gene2023 9.4e-19 100.1 Chlamydiae 3.2.1.20 ko:K01187,ko:K03466,ko:K07017 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000,ko03036 3.A.12 GH31 Bacteria 2JH2N@204428,COG2819@1,COG2819@2 NA|NA|NA S hydrolase of the alpha beta superfamily OINAGBCE_00221 1444711.CCJF01000004_gene2024 6.4e-73 280.8 Chlamydiae CP_0228 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFRJ@204428,COG1579@1,COG1579@2 NA|NA|NA S C4-type zinc ribbon domain OINAGBCE_00222 1437425.CSEC_1107 1.6e-310 1071.6 Chlamydiae acnA 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2JG1H@204428,COG1048@1,COG1048@2 NA|NA|NA C Aconitase family (aconitate hydratase) OINAGBCE_00223 1444711.CCJF01000004_gene2352 1.1e-59 236.5 Chlamydiae 2.7.7.7 ko:K02342,ko:K10857,ko:K13288 ko00230,ko00240,ko01100,ko03008,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03008,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko03032,ko03400 Bacteria 2JG5Z@204428,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease OINAGBCE_00224 765952.PUV_10300 4.2e-99 367.9 Chlamydiae dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 2JFE0@204428,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria OINAGBCE_00225 765952.PUV_10310 3.9e-104 385.2 Chlamydiae CP_0674 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 2JFIM@204428,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria OINAGBCE_00226 765952.PUV_27220 9.2e-71 273.9 Chlamydiae yddE 5.3.3.17 ko:K06998 ko00405,ko01130,ko02024,map00405,map01130,map02024 M00835 ko00000,ko00001,ko00002,ko01000 Bacteria 2JH11@204428,COG0384@1,COG0384@2 NA|NA|NA S Phenazine biosynthesis-like protein OINAGBCE_00227 716544.wcw_1391 1.5e-118 433.0 Chlamydiae desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2JFP0@204428,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase OINAGBCE_00228 1444711.CCJF01000004_gene2454 7.5e-61 240.7 Chlamydiae GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 ko:K07019 ko00000 Bacteria 2JH18@204428,COG0429@1,COG0429@2 NA|NA|NA S Alpha/beta hydrolase family OINAGBCE_00230 765952.PUV_08340 2.7e-29 135.2 Chlamydiae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2JGB9@204428,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain OINAGBCE_00231 765952.PUV_08320 2.3e-80 305.1 Chlamydiae dcd GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFD9@204428,COG0717@1,COG0717@2 NA|NA|NA F Belongs to the dCTP deaminase family OINAGBCE_00232 765952.PUV_08300 2.8e-62 245.7 Chlamydiae tlyC_1 Bacteria 2JFRE@204428,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain OINAGBCE_00233 765952.PUV_08290 1.6e-78 300.1 Chlamydiae gldE Bacteria 2JFJ2@204428,COG1253@1,COG1253@2 NA|NA|NA S Domain of unknown function DUF21 OINAGBCE_00236 264201.pc0772 1.5e-213 748.8 Chlamydiae accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFW0@204428,COG0439@1,COG0439@2 NA|NA|NA I Biotin carboxylase OINAGBCE_00237 1444712.BN1013_01753 8.3e-37 160.2 Chlamydiae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 2JGBI@204428,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA OINAGBCE_00238 1444711.CCJF01000005_gene1727 3.8e-59 234.6 Chlamydiae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2JFYK@204428,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase OINAGBCE_00239 1444711.CCJF01000005_gene1728 3.7e-86 324.7 Chlamydiae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFP2@204428,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family OINAGBCE_00240 1444711.CCJF01000005_gene1741 5.5e-32 144.8 Chlamydiae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFXU@204428,COG0196@1,COG0196@2 NA|NA|NA H riboflavin biosynthesis protein OINAGBCE_00241 1444712.BN1013_01743 2.8e-61 241.9 Chlamydiae truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2JFXN@204428,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs OINAGBCE_00242 264201.pc0760 7.1e-25 120.2 Chlamydiae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 2JH1H@204428,COG0858@1,COG0858@2 NA|NA|NA J Ribosome-binding factor A OINAGBCE_00243 1444712.BN1013_01745 7.5e-236 823.9 Chlamydiae infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2JFVG@204428,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex OINAGBCE_00244 264201.pc0762 6.9e-157 560.5 Chlamydiae nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 2JFHD@204428,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination OINAGBCE_00245 1444711.CCJF01000005_gene1735 1.2e-263 915.6 Chlamydiae rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 Bacteria 2JFJ4@204428,COG0539@1,COG0539@2 NA|NA|NA J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence OINAGBCE_00246 1444711.CCJF01000005_gene1734 7.3e-80 303.9 Chlamydiae lysC 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFUC@204428,COG0527@1,COG0527@2 NA|NA|NA E Amino acid kinase family OINAGBCE_00247 765952.PUV_20190 2.1e-24 119.0 Chlamydiae Bacteria 2BVXU@1,2JGBD@204428,32V9S@2 NA|NA|NA OINAGBCE_00248 1444712.BN1013_01503 1.8e-26 126.7 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_00249 1444712.BN1013_01503 9.1e-37 161.0 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_00250 211165.AJLN01000153_gene630 1.4e-13 82.0 Stigonemataceae Bacteria 1G9J8@1117,1JJ0Y@1189,COG2002@1,COG2002@2 NA|NA|NA K SpoVT / AbrB like domain OINAGBCE_00251 1123400.KB904748_gene321 1.7e-21 109.0 Gammaproteobacteria vapC Bacteria 1N9JM@1224,1SYAQ@1236,COG5611@1,COG5611@2 NA|NA|NA S PIN domain OINAGBCE_00253 998088.B565_0726 1.3e-76 293.5 Aeromonadales nemA Bacteria 1MVIX@1224,1RMFI@1236,1Y4Z7@135624,COG1902@1,COG1902@2 NA|NA|NA C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family OINAGBCE_00254 86416.Clopa_0521 6.4e-33 147.5 Clostridiaceae Bacteria 1V44X@1239,24HI1@186801,36J30@31979,COG1309@1,COG1309@2 NA|NA|NA K PFAM Bacterial regulatory proteins, tetR family OINAGBCE_00255 1291050.JAGE01000001_gene1413 2.3e-11 74.7 Clostridia Bacteria 1VEVQ@1239,24RVC@186801,2E5YB@1,330N1@2 NA|NA|NA S Putative zinc ribbon domain OINAGBCE_00258 1121091.AUMP01000024_gene2978 1.8e-105 390.2 Bacilli alkJ 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1UY91@1239,4HBD1@91061,COG2303@1,COG2303@2 NA|NA|NA E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate OINAGBCE_00259 1242864.D187_001834 1.7e-37 164.1 Myxococcales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1MUTS@1224,2X289@28221,2YUWN@29,4377E@68525,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A OINAGBCE_00261 1437425.CSEC_0988 6.4e-162 577.4 Chlamydiae ko:K06876 ko00000 Bacteria 2JGMK@204428,COG3046@1,COG3046@2 NA|NA|NA S Deoxyribodipyrimidine photo-lyase-related protein OINAGBCE_00262 1437425.CSEC_2078 3.7e-106 392.1 Chlamydiae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 ko:K00014,ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1860 Bacteria 2JFIF@204428,COG0169@1,COG0169@2,COG0710@1,COG0710@2 NA|NA|NA E Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) OINAGBCE_00263 1437425.CSEC_2080 5.2e-129 467.6 Chlamydiae aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iIT341.HP0663,iJN678.aroC,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Bacteria 2JFU7@204428,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system OINAGBCE_00265 765952.PUV_18740 3e-57 228.4 Chlamydiae MA20_24580 Bacteria 2JG59@204428,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase OINAGBCE_00267 162425.CADANIAP00006646 2.2e-09 70.9 Eurotiales Fungi 20ESW@147545,39M4R@33154,3NZCA@4751,3QN0E@4890,3S7JV@5042,KOG0201@1,KOG0201@2759 NA|NA|NA T Serine threonin protein kinase OINAGBCE_00268 469381.Dpep_1532 3.8e-27 127.9 Synergistetes Bacteria 3TBPJ@508458,COG2445@1,COG2445@2 NA|NA|NA S Protein of unknown function DUF86 OINAGBCE_00269 357808.RoseRS_2954 3.1e-17 95.1 Bacteria Bacteria COG1669@1,COG1669@2 NA|NA|NA S nucleotidyltransferase activity OINAGBCE_00271 86106.I862_07370 2.7e-23 114.8 Rickettsiales GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K07171 ko00000,ko01000,ko02048 Bacteria 1N0JV@1224,2UFG0@28211,47GG9@766,COG2337@1,COG2337@2 NA|NA|NA L PemK-like, MazF-like toxin of type II toxin-antitoxin system OINAGBCE_00273 579137.Metvu_0936 9.6e-22 109.4 Euryarchaeota ko:K07075 ko00000 Archaea 2Y03V@28890,COG1669@1,arCOG01206@2157 NA|NA|NA S Nucleotidyltransferase domain OINAGBCE_00274 247490.KSU1_C0554 5e-09 66.2 Planctomycetes Bacteria 2J19H@203682,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 OINAGBCE_00275 1437425.CSEC_0640 4e-56 225.3 Chlamydiae ko:K01993 ko00000 Bacteria 2JG8I@204428,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family OINAGBCE_00276 1444712.BN1013_00147 2.9e-64 253.1 Chlamydiae ko:K18903 M00698 ko00000,ko00002,ko01504,ko02000 1.B.17.3.3 Bacteria 2JGXS@204428,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein OINAGBCE_00277 323261.Noc_0402 2.5e-98 365.9 Chromatiales Bacteria 1QUMJ@1224,1T2RP@1236,1WZYU@135613,COG4783@1,COG4783@2 NA|NA|NA S peptidase M48, Ste24p OINAGBCE_00278 251221.35211407 5.5e-07 60.1 Cyanobacteria yiiF Bacteria 1GAZS@1117,COG3905@1,COG3905@2 NA|NA|NA K Ribbon-helix-helix protein, copG family OINAGBCE_00279 1123354.AUDR01000014_gene850 1.9e-31 142.1 Betaproteobacteria ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1RJDP@1224,2WGAS@28216,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase OINAGBCE_00281 765952.PUV_20630 7.9e-176 625.5 Chlamydiae Bacteria 2JFH5@204428,COG3209@1,COG3209@2 NA|NA|NA M Rhs family OINAGBCE_00286 765952.PUV_10870 8.3e-15 89.4 Chlamydiae recX 2.4.1.337 ko:K03565,ko:K06867,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 2JHE1@204428,COG0666@1,COG0666@2,COG2137@1,COG2137@2 NA|NA|NA S Ankyrin repeat OINAGBCE_00287 886293.Sinac_2843 5.5e-68 264.2 Planctomycetes ddpX 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 2IWSU@203682,COG1680@1,COG1680@2,COG2173@1,COG2173@2 NA|NA|NA MV Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide OINAGBCE_00288 754476.Q7A_1552 1.1e-23 117.5 Gammaproteobacteria Bacteria 1RDBY@1224,1SBXH@1236,2A25B@1,30QFQ@2 NA|NA|NA S Protochlamydia outer membrane protein OINAGBCE_00289 1444711.CCJF01000004_gene1869 0.0 1212.6 Chlamydiae mfd 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 GT51 Bacteria 2JFGI@204428,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site OINAGBCE_00290 264201.pc1519 2.8e-298 1031.2 Chlamydiae alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 Bacteria 2JGVQ@204428,COG0013@1,COG0013@2 NA|NA|NA J tRNA synthetases class II (A) OINAGBCE_00293 765952.PUV_08810 4.1e-59 235.3 Bacteria cdd GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 iECO103_1326.ECO103_2618 Bacteria COG0295@1,COG0295@2 NA|NA|NA F cytidine deaminase activity OINAGBCE_00295 485915.Dret_2367 2.1e-119 436.0 Desulfovibrionales ko:K07133 ko00000 Bacteria 1MWDX@1224,2MF0W@213115,2WVDX@28221,4302U@68525,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_00296 658187.LDG_6000 1.4e-125 456.4 Legionellales 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1JFTD@118969,1N458@1224,1RNYG@1236,COG3550@1,COG3550@2 NA|NA|NA S Pfam:HipA_N OINAGBCE_00297 348824.LPU83_3086 3.1e-26 124.4 Rhizobiaceae ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1N8D1@1224,2UA7K@28211,4BNW5@82115,COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding OINAGBCE_00298 765952.PUV_26940 3.6e-25 122.9 Chlamydiae Bacteria 2A5XQ@1,2JG24@204428,30UPR@2 NA|NA|NA OINAGBCE_00299 765952.PUV_13630 4.2e-152 544.7 Chlamydiae Bacteria 28IU8@1,2JFPH@204428,2Z8T0@2 NA|NA|NA OINAGBCE_00300 1444711.CCJF01000005_gene1242 6.8e-08 66.2 Chlamydiae prgA Bacteria 2JHCN@204428,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation OINAGBCE_00302 765952.PUV_13610 5.2e-104 384.8 Chlamydiae rfaE 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JFQT@204428,COG2870@1,COG2870@2 NA|NA|NA H pfkB family carbohydrate kinase OINAGBCE_00303 1444711.CCJF01000004_gene2384 6.4e-118 430.6 Chlamydiae hldD 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JFMJ@204428,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose OINAGBCE_00304 716544.wcw_0819 2.4e-38 165.2 Chlamydiae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG41@204428,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA OINAGBCE_00305 264201.pc1591 2.4e-24 118.2 Chlamydiae rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGBA@204428,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit OINAGBCE_00306 1437425.CSEC_1022 4.6e-39 167.2 Chlamydiae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2JG6I@204428,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA OINAGBCE_00307 648996.Theam_0298 1.1e-37 163.3 Aquificae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2G42F@200783,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis OINAGBCE_00308 1444711.CCJF01000004_gene2375 1.8e-48 199.1 Chlamydiae ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2JG0I@204428,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance OINAGBCE_00309 716544.wcw_0814 1.8e-66 259.6 Chlamydiae prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 2JFNR@204428,COG0462@1,COG0462@2 NA|NA|NA F N-terminal domain of ribose phosphate pyrophosphokinase OINAGBCE_00313 56780.SYN_01514 9.4e-93 347.4 Syntrophobacterales ko:K07133 ko00000 Bacteria 1R3UA@1224,2MQ4T@213462,2WJ04@28221,42N3U@68525,COG1373@1,COG1373@2 NA|NA|NA S AAA domain OINAGBCE_00314 264201.pc0229 3.7e-196 691.0 Chlamydiae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFIG@204428,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine OINAGBCE_00316 1437425.CSEC_1615 1.6e-247 862.1 Chlamydiae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 2JFK6@204428,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 OINAGBCE_00317 716544.wcw_1777 6.7e-64 250.8 Chlamydiae lplA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 iBWG_1329.BWG_4078,iE2348C_1286.E2348C_4684,iECDH10B_1368.ECDH10B_4544,iECDH1ME8569_1439.ECDH1ME8569_4242,iEcDH1_1363.EcDH1_3612,iJO1366.b4386,iSDY_1059.SDY_4647,iY75_1357.Y75_RS22890 Bacteria 2JG2Z@204428,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase OINAGBCE_00318 765952.PUV_06970 7.8e-87 327.0 Chlamydiae nifU ko:K04488,ko:K07126,ko:K13819 ko00000 Bacteria 2JFTX@204428,COG0694@1,COG0694@2,COG0822@1,COG0822@2 NA|NA|NA CO NifU protein OINAGBCE_00319 1444711.CCJF01000005_gene597 1.3e-85 323.6 Chlamydiae yfhO_2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2JFKX@204428,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V OINAGBCE_00320 716544.wcw_0297 2.5e-73 282.0 Chlamydiae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2JFCZ@204428,COG0588@1,COG0588@2 NA|NA|NA F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate OINAGBCE_00321 331113.SNE_A03060 2.6e-66 258.8 Chlamydiae rluF GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2JFFS@204428,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family OINAGBCE_00323 716544.wcw_0295 2.1e-22 114.0 Chlamydiae Bacteria 2DSZ2@1,2JG9G@204428,32UU1@2 NA|NA|NA OINAGBCE_00324 1121271.AUCM01000010_gene2368 1.1e-67 263.5 Alphaproteobacteria ko:K02031,ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1NU4K@1224,2TQTV@28211,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily OINAGBCE_00325 926567.TheveDRAFT_0012 1.2e-64 253.4 Synergistetes appD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02031,ko:K02032,ko:K15269,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 2.A.7.3.3,3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 3TA26@508458,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily OINAGBCE_00326 765952.PUV_06440 2.2e-61 242.3 Chlamydiae CP_0066 ko:K07220 ko00000 Bacteria 2JFZT@204428,COG1392@1,COG1392@2 NA|NA|NA P Protein of unknown function DUF47 OINAGBCE_00327 1444711.CCJF01000005_gene301 1.3e-123 449.9 Chlamydiae pitA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K03306 ko00000 2.A.20 Bacteria 2JFPI@204428,COG0306@1,COG0306@2 NA|NA|NA P Phosphate OINAGBCE_00328 716544.wcw_0287 6.2e-110 404.8 Chlamydiae yejE GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 ko:K02034,ko:K13895,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00349,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25 Bacteria 2JFT4@204428,COG1173@1,COG1173@2,COG4239@1,COG4239@2 NA|NA|NA EP permease protein OINAGBCE_00329 1444711.CCJF01000005_gene297 1.6e-136 493.0 Chlamydiae oppB ko:K02033,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 2JFQS@204428,COG0601@1,COG0601@2 NA|NA|NA P permease protein OINAGBCE_00330 264201.pc0103 5.5e-180 637.9 Chlamydiae oppA_5 ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 2JFWS@204428,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle OINAGBCE_00331 1444711.CCJF01000005_gene293 0.0 1139.8 Chlamydiae glgP 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 2JGP1@204428,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties OINAGBCE_00332 716544.wcw_0278 1.1e-30 140.6 Chlamydiae fliY ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2JG7C@204428,COG0834@1,COG0834@2 NA|NA|NA ET Periplasmic amino acid-binding protein OINAGBCE_00333 264201.pc1868 2.2e-57 229.2 Chlamydiae yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 2JG1Z@204428,COG1496@1,COG1496@2 NA|NA|NA S Multi-copper polyphenol oxidoreductase laccase OINAGBCE_00335 269797.Mbar_A1408 4.3e-63 248.8 Euryarchaeota Archaea 2XWFH@28890,COG3547@1,arCOG03585@2157 NA|NA|NA L COG3547 Transposase and inactivated derivatives OINAGBCE_00341 1437425.CSEC_0936 1e-10 74.3 Chlamydiae Bacteria 2EU3I@1,2JGHP@204428,33MZN@2 NA|NA|NA OINAGBCE_00342 1444711.CCJF01000004_gene1953 9.1e-20 104.0 Chlamydiae mip 5.2.1.8 ko:K01802,ko:K03773 ko00000,ko01000,ko03110 Bacteria 2JFN0@204428,COG0545@1,COG0545@2 NA|NA|NA M Peptidyl-prolyl cis-trans OINAGBCE_00343 1094715.CM001375_gene198 4e-16 91.3 Legionellales algA Bacteria 1JEDC@118969,1N6QA@1224,1S922@1236,COG0454@1,COG0456@2,COG0662@1,COG0662@2 NA|NA|NA K Acetyltransferase (GNAT) domain OINAGBCE_00344 316055.RPE_0679 2.8e-88 332.4 Bradyrhizobiaceae Bacteria 1N207@1224,2U1EH@28211,3K65K@41294,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain OINAGBCE_00345 765952.PUV_25230 3.7e-23 114.0 Bacteria 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria COG2865@1,COG2865@2 NA|NA|NA OINAGBCE_00346 264201.pc1761 2.8e-291 1007.7 Chlamydiae glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 ko:K00700,ko:K01187,ko:K01236,ko:K17734 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 M00565 R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13,GH31 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 2JFFB@204428,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position OINAGBCE_00347 562743.JH976444_gene578 2.9e-17 94.4 Bacilli Bacteria 1V1TP@1239,2EVGP@1,33NX2@2,4HJHR@91061 NA|NA|NA OINAGBCE_00348 1444711.CCJF01000005_gene1304 3.1e-112 412.5 Chlamydiae tamA ko:K07278 ko00000,ko02000 1.B.33.2.4 Bacteria 2JFF4@204428,COG0729@1,COG0729@2 NA|NA|NA M Surface antigen OINAGBCE_00350 331113.SNE_A22960 5.4e-129 468.0 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_00351 566466.NOR53_1874 3.5e-13 82.8 unclassified Gammaproteobacteria licA 1.1.1.34,2.7.1.72,2.7.1.89 ko:K00021,ko:K04343,ko:K07251,ko:K09965,ko:K18844 ko00730,ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00730,map00900,map01100,map01110,map01130,map04152,map04976 M00095,M00766 R02082,R02134,R02225 RC00002,RC00004,RC00017,RC00078,RC00644 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1J9XT@118884,1Q5C3@1224,1SI6I@1236,COG0510@1,COG0510@2 NA|NA|NA H Choline/ethanolamine kinase OINAGBCE_00352 1444711.CCJF01000005_gene706 2e-57 229.9 Chlamydiae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 2JFGZ@204428,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family OINAGBCE_00353 879212.DespoDRAFT_03043 7.6e-135 487.3 Deltaproteobacteria Bacteria 1MVI1@1224,2WU1Y@28221,42Y93@68525,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) OINAGBCE_00357 886293.Sinac_2513 1.2e-222 779.6 Planctomycetes topB 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 2J2NP@203682,COG0550@1,COG0550@2 NA|NA|NA L C-terminal repeat of topoisomerase OINAGBCE_00358 227377.CBU_1638 8.9e-122 443.7 Gammaproteobacteria ko:K07133 ko00000 Bacteria 1R65E@1224,1RYB1@1236,COG1373@1,COG1373@2 NA|NA|NA S AAA domain OINAGBCE_00361 1444712.BN1013_01159 1.6e-73 283.1 Chlamydiae add 3.5.4.2,3.5.4.4 ko:K01488,ko:K19572,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 Bacteria 2JGXX@204428,COG1816@1,COG1816@2 NA|NA|NA F Adenosine/AMP deaminase OINAGBCE_00363 1444711.CCJF01000005_gene1323 1.6e-110 406.4 Chlamydiae pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2JFHR@204428,COG0508@1,COG0508@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) OINAGBCE_00364 331113.SNE_A08110 7e-141 506.9 Chlamydiae pdhB 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2753 Bacteria 2JFIU@204428,COG0022@1,COG0022@2 NA|NA|NA C Pyruvate dehydrogenase E1 OINAGBCE_00365 264201.pc1733 2e-122 445.7 Chlamydiae pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2JFFX@204428,COG1071@1,COG1071@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) OINAGBCE_00367 1444711.CCJF01000005_gene1192 7.2e-41 174.1 Chlamydiae Bacteria 2JGA0@204428,COG0500@1,COG0500@2 NA|NA|NA Q Histone methylation protein DOT1 OINAGBCE_00368 316067.Geob_1146 2.8e-28 131.7 Deltaproteobacteria vapC 2.3.1.30 ko:K00640,ko:K07062 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 1RIB5@1224,2WRAU@28221,42W91@68525,COG1487@1,COG1487@2 NA|NA|NA S PIN domain OINAGBCE_00369 1304885.AUEY01000093_gene1587 3.1e-09 67.8 Desulfobacterales Bacteria 1NBSZ@1224,2MPCN@213118,2WXB2@28221,4332I@68525,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin Phd_YefM, type II toxin-antitoxin system OINAGBCE_00370 331113.SNE_A17930 1.4e-113 416.0 Chlamydiae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2JFE5@204428,COG0024@1,COG0024@2 NA|NA|NA E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed OINAGBCE_00371 1278073.MYSTI_00036 4.4e-152 544.3 Myxococcales fba 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iJN746.PP_4960 Bacteria 1MURX@1224,2WJCJ@28221,2Z2S1@29,42MK7@68525,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II OINAGBCE_00373 264201.pc1118 2.2e-229 802.0 Chlamydiae yyaL ko:K06888 ko00000 Bacteria 2JFE4@204428,COG1331@1,COG1331@2 NA|NA|NA O Protein of unknown function, DUF255 OINAGBCE_00374 1437425.CSEC_0539 4.5e-71 274.6 Chlamydiae Bacteria 2JHHE@204428,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain OINAGBCE_00375 716544.wcw_0958 6.2e-65 255.8 Chlamydiae Bacteria 2JFDZ@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_00377 1033802.SSPSH_003757 2.3e-63 249.6 Gammaproteobacteria wabK Bacteria 1QEP7@1224,1RZIT@1236,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 OINAGBCE_00378 716544.wcw_1109 1.5e-26 125.9 Chlamydiae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2JGC0@204428,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA OINAGBCE_00379 1444711.CCJF01000005_gene1405 3.6e-219 767.7 Chlamydiae pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2JFCN@204428,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates OINAGBCE_00380 264201.pc0825 2.3e-67 262.3 Chlamydiae kdsB 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JFZ3@204428,COG1212@1,COG1212@2 NA|NA|NA F Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria OINAGBCE_00381 411464.DESPIG_02938 5.4e-16 90.1 Desulfovibrionales rbpA Bacteria 1N0P8@1224,2MH3Y@213115,2WQ1E@28221,43B6G@68525,COG0724@1,COG0724@2 NA|NA|NA S PFAM RNP-1 like RNA-binding protein OINAGBCE_00382 716544.wcw_1076 3.2e-25 123.2 Chlamydiae 3.1.3.16 ko:K17506,ko:K20074 ko00000,ko01000,ko01009 Bacteria 2JHF9@204428,COG0631@1,COG0631@2 NA|NA|NA T Sigma factor PP2C-like phosphatases OINAGBCE_00383 1444712.BN1013_02187 1.7e-51 211.8 Chlamydiae ko:K07289,ko:K09800 ko00000,ko02000 Bacteria 2JFZM@204428,COG2982@1,COG2982@2 NA|NA|NA M Protein involved in outer membrane biogenesis OINAGBCE_00384 573065.Astex_1042 9.3e-58 230.3 Caulobacterales sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 1MVW2@1224,2KGAC@204458,2TQYJ@28211,COG0605@1,COG0605@2 NA|NA|NA C Destroys radicals which are normally produced within the cells and which are toxic to biological systems OINAGBCE_00386 161934.XP_010680008.1 1.5e-34 154.5 Streptophyta Viridiplantae 2QUK3@2759,37QBA@33090,3GXAC@35493,COG2304@1 NA|NA|NA O VWA / Hh protein intein-like OINAGBCE_00388 1444711.CCJF01000005_gene359 7.1e-163 580.9 Chlamydiae ko:K06158 ko00000,ko03012 Bacteria 2JFNM@204428,COG0488@1,COG0488@2 NA|NA|NA S ATPase components of various ABC-type transport systems, contain duplicated ATPase OINAGBCE_00389 640511.BC1002_6129 4.5e-20 103.6 Burkholderiaceae 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1K9M1@119060,1N7BG@1224,2VY0B@28216,COG4118@1,COG4118@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module OINAGBCE_00390 398527.Bphyt_4379 1.4e-28 132.5 Burkholderiaceae Bacteria 1KFTZ@119060,1NA89@1224,2VUYN@28216,COG3744@1,COG3744@2 NA|NA|NA S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology OINAGBCE_00391 717605.Theco_2802 1.4e-21 109.0 Bacilli Bacteria 1VGI3@1239,4HQ9K@91061,COG1708@1,COG1708@2 NA|NA|NA S Nucleotidyltransferase domain OINAGBCE_00392 558169.AGAV01000018_gene3480 3.1e-31 141.4 Bacilli Bacteria 1V6R7@1239,4HKW0@91061,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase substrate binding protein like OINAGBCE_00396 397291.C804_05509 6e-75 288.1 unclassified Lachnospiraceae Bacteria 1TQUZ@1239,248AM@186801,27KAM@186928,COG2263@1,COG2263@2 NA|NA|NA J Methyltransferase domain OINAGBCE_00398 293826.Amet_4266 6.1e-31 140.2 Clostridiaceae phhB GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 ko:K01724 ko00790,map00790 R04734 RC01208 ko00000,ko00001,ko01000,ko04147 Bacteria 1VERE@1239,24NE1@186801,36SAJ@31979,COG2154@1,COG2154@2 NA|NA|NA H Pterin 4 alpha carbinolamine dehydratase OINAGBCE_00400 1034943.BN1094_03152 1.2e-09 71.6 Legionellales Bacteria 1JFBH@118969,1QBUX@1224,1T7FN@1236,2APFV@1,31EIN@2 NA|NA|NA OINAGBCE_00401 765952.PUV_10060 0.0 1153.3 Chlamydiae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2JFVD@204428,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family OINAGBCE_00404 1437425.CSEC_2357 8.3e-124 450.3 Chlamydiae ko:K03699 ko00000,ko02042 Bacteria 2JFWG@204428,COG1253@1,COG1253@2 NA|NA|NA S Domain of unknown function DUF21 OINAGBCE_00405 1444712.BN1013_01851 1e-206 726.9 Chlamydiae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2JFD4@204428,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs OINAGBCE_00407 765952.PUV_09270 8.9e-46 190.3 Chlamydiae CP_0247 Bacteria 2JFZV@204428,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) OINAGBCE_00408 716544.wcw_1044 1.5e-25 123.2 Chlamydiae CP_0247 Bacteria 2JFZV@204428,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) OINAGBCE_00410 716544.wcw_1038 1e-31 143.3 Chlamydiae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2JG8S@204428,COG0319@1,COG0319@2 NA|NA|NA J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA OINAGBCE_00411 765952.PUV_10410 8.1e-86 323.9 Chlamydiae tlyC Bacteria 2JFV2@204428,COG1253@1,COG1253@2 NA|NA|NA S Domain protein OINAGBCE_00412 1121468.AUBR01000009_gene2159 1e-82 314.3 Thermoanaerobacterales rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,248G8@186801,42F5Q@68295,COG1418@1,COG1418@2 NA|NA|NA D Endoribonuclease that initiates mRNA decay OINAGBCE_00414 716544.wcw_0628 3.6e-46 192.2 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis OINAGBCE_00415 926554.KI912675_gene2174 2.4e-08 66.2 Bacteria Bacteria 29A5E@1,2ZX6F@2 NA|NA|NA OINAGBCE_00416 500153.JOEK01000001_gene4139 4.4e-11 73.9 Actinobacteria Bacteria 2GMBB@201174,COG1475@1,COG1475@2,COG3209@1,COG3209@2 NA|NA|NA M COG3209 Rhs family protein OINAGBCE_00417 264201.pc1720 1.3e-101 376.3 Chlamydiae fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iYO844.BSU11330 Bacteria 2JFVI@204428,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids OINAGBCE_00418 1444711.CCJF01000005_gene1334 2.1e-102 379.0 Chlamydiae fabD 2.3.1.39 ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Bacteria 2JFRU@204428,COG0331@1,COG0331@2 NA|NA|NA I malonyl CoA-acyl carrier protein transacylase OINAGBCE_00419 716544.wcw_1187 1.5e-71 276.2 Chlamydiae Bacteria 2JFE8@204428,COG1028@1,COG1028@2 NA|NA|NA IQ Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis OINAGBCE_00420 218497.CAB473 3.1e-18 97.4 Bacteria acpP ko:K02078 ko00000,ko00001 Bacteria COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis OINAGBCE_00421 765952.PUV_16170 3.7e-170 604.7 Chlamydiae mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 2JGWT@204428,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter OINAGBCE_00422 264201.pc1116 3.2e-256 891.0 Chlamydiae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2JFS9@204428,COG1217@1,COG1217@2 NA|NA|NA T Elongation factor G C-terminus OINAGBCE_00423 716544.wcw_0260 2.5e-13 84.3 Chlamydiae Bacteria 2FCZR@1,2JHB3@204428,3452C@2 NA|NA|NA OINAGBCE_00424 1444711.CCJF01000005_gene317 8.3e-45 187.2 Chlamydiae prmA 2.1.1.222,2.1.1.64 ko:K00568,ko:K02687 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2JGAK@204428,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase (PrmA) OINAGBCE_00425 716544.wcw_1250 8.4e-59 233.8 Chlamydiae adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 Bacteria 2JG11@204428,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism OINAGBCE_00436 316055.RPE_0679 6.1e-99 367.9 Bradyrhizobiaceae Bacteria 1N207@1224,2U1EH@28211,3K65K@41294,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain OINAGBCE_00437 1444711.CCJF01000005_gene1677 6.4e-263 913.3 Chlamydiae acsA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JFRM@204428,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA OINAGBCE_00438 293826.Amet_1444 2.3e-46 192.2 Clostridia ko:K07282 ko00000 Bacteria 1V20N@1239,24AI2@186801,COG2843@1,COG2843@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase OINAGBCE_00439 243164.DET1516 2e-18 99.4 Dehalococcoidia arsR ko:K03833,ko:K07061,ko:K18996,ko:K19689 ko00000,ko01000,ko01002,ko02048,ko03012,ko03032 Bacteria 2GAUP@200795,34DDZ@301297,COG0640@1,COG0640@2,COG1669@1,COG1669@2 NA|NA|NA K Nucleotidyltransferase domain OINAGBCE_00440 880072.Desac_1551 1.5e-18 99.4 Bacteria Bacteria 2EEHM@1,338BG@2 NA|NA|NA OINAGBCE_00441 264201.pc0391 1.2e-31 143.3 Chlamydiae Bacteria 2EF13@1,2JG4P@204428,31W4C@2 NA|NA|NA S Lipopolysaccharide-assembly OINAGBCE_00442 765952.PUV_22310 4.8e-81 308.1 Chlamydiae bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria 2JG4X@204428,COG4105@1,COG4105@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane OINAGBCE_00443 1048834.TC41_2787 5.5e-96 358.2 Bacilli Bacteria 1TP6X@1239,4IQRT@91061,COG2271@1,COG2271@2 NA|NA|NA G Major facilitator superfamily OINAGBCE_00444 1396.DJ87_2549 4.7e-86 325.5 Bacteria Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 OINAGBCE_00445 765952.PUV_25560 1.2e-120 439.9 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups OINAGBCE_00446 716544.wcw_0260 3.3e-57 229.9 Chlamydiae Bacteria 2FCZR@1,2JHB3@204428,3452C@2 NA|NA|NA OINAGBCE_00448 1230343.CANP01000028_gene2059 5.5e-144 517.7 Legionellales ko:K07133 ko00000 Bacteria 1JFUU@118969,1MWDX@1224,1RYD6@1236,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_00449 588596.U9SNA1 8.2e-09 68.6 Opisthokonta DSTYK GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0008152,GO:0009719,GO:0009790,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0016020,GO:0016301,GO:0016310,GO:0016323,GO:0016324,GO:0016740,GO:0016772,GO:0016773,GO:0019220,GO:0019222,GO:0019538,GO:0023051,GO:0023052,GO:0023056,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033674,GO:0035556,GO:0036211,GO:0040036,GO:0042221,GO:0042325,GO:0042327,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043170,GO:0043408,GO:0043410,GO:0043412,GO:0043549,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044344,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045177,GO:0045743,GO:0045937,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048568,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051716,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070372,GO:0070374,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0071944,GO:0080090,GO:0090287,GO:0098590,GO:0140096,GO:1901564,GO:1902531,GO:1902533 2.7.11.1 ko:K16288 ko00000,ko01000,ko01001 Opisthokonta 38F12@33154,COG0515@1,KOG0192@2759 NA|NA|NA T protein serine/threonine/tyrosine kinase activity OINAGBCE_00450 716544.wcw_1535 3.8e-100 371.3 Chlamydiae Bacteria 28MRF@1,2JFCW@204428,2ZB02@2 NA|NA|NA OINAGBCE_00451 765952.PUV_02450 8.8e-156 557.8 Chlamydiae rapA 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2JFHJ@204428,COG0553@1,COG0553@2 NA|NA|NA L swi snf helicase family OINAGBCE_00452 1444711.CCJF01000004_gene1939 6.6e-09 66.2 Chlamydiae Bacteria 2EPIQ@1,2JGHJ@204428,33H5C@2 NA|NA|NA OINAGBCE_00453 118005.AWNK01000004_gene1058 2.1e-122 445.7 Bacteria GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046983,GO:0070566,GO:0070733,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 Bacteria COG3177@1,COG3177@2 NA|NA|NA D Filamentation induced by cAMP protein fic OINAGBCE_00454 497964.CfE428DRAFT_6352 1.3e-21 108.6 Verrucomicrobia XK27_08510 Bacteria 46UU5@74201,COG1061@1,COG1061@2,COG2852@1,COG2852@2,COG4951@1,COG4951@2 NA|NA|NA L Protein of unknown function (DUF559) OINAGBCE_00455 497964.CfE428DRAFT_6352 9.7e-66 256.5 Verrucomicrobia XK27_08510 Bacteria 46UU5@74201,COG1061@1,COG1061@2,COG2852@1,COG2852@2,COG4951@1,COG4951@2 NA|NA|NA L Protein of unknown function (DUF559) OINAGBCE_00456 1034943.BN1094_02514 5.7e-08 64.3 Gammaproteobacteria Bacteria 1RFVU@1224,1S5UC@1236,COG4461@1,COG4461@2 NA|NA|NA S Domain of unknown function (DUF4431) OINAGBCE_00457 693986.MOC_0961 9.6e-13 80.9 Methylobacteriaceae Bacteria 1JVWZ@119045,1PGP6@1224,2V0FP@28211,COG1388@1,COG1388@2,COG5283@1,COG5283@2 NA|NA|NA M heme binding OINAGBCE_00460 163908.KB235896_gene2619 2e-19 102.1 Nostocales Bacteria 1G845@1117,1HU71@1161,COG5606@1,COG5606@2 NA|NA|NA K Helix-turn-helix domain OINAGBCE_00461 1444712.BN1013_00775 6e-27 127.1 Bacteria Bacteria COG4679@1,COG4679@2 NA|NA|NA K PFAM Phage derived protein Gp49-like (DUF891) OINAGBCE_00463 1268635.Loa_02527 9e-47 193.4 Legionellales ada 2.1.1.63,3.2.2.21 ko:K00567,ko:K10778,ko:K13529,ko:K13530,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1JD80@118969,1N2YQ@1224,1RPR3@1236,COG0350@1,COG0350@2,COG2169@1,COG2169@2 NA|NA|NA F Metal binding domain of Ada OINAGBCE_00464 673862.BABL1_244 3.7e-59 235.0 Deltaproteobacteria glnQ 3.6.3.21 ko:K01990,ko:K02028,ko:K09810,ko:K17063 ko02010,map02010 M00236,M00254,M00255,M00587 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125,3.A.1.3,3.A.1.3.12 Bacteria 1MU9Q@1224,2WITR@28221,42M0S@68525,COG1126@1,COG1126@2 NA|NA|NA E PFAM ABC transporter related OINAGBCE_00465 1306947.ARQD01000001_gene660 3.3e-54 218.4 unclassified Bacteria glnP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2NPKZ@2323,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component OINAGBCE_00469 765952.PUV_14670 2.8e-27 128.6 Chlamydiae Bacteria 2CFTD@1,2JGCP@204428,32RKN@2 NA|NA|NA S Protein of unknown function (DUF2937) OINAGBCE_00471 1444711.CCJF01000005_gene678 9.3e-113 413.3 Chlamydiae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFIG@204428,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine OINAGBCE_00473 716544.wcw_0323 2.1e-97 362.5 Chlamydiae kamA GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 R00461 RC00303 ko00000,ko00001,ko01000,ko03012 iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Bacteria 2JFD7@204428,COG1509@1,COG1509@2 NA|NA|NA C 4Fe-4S single cluster domain OINAGBCE_00474 264201.pc1724 3.7e-52 211.5 Chlamydiae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2JG40@204428,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO OINAGBCE_00475 264201.pc1726 7.7e-186 657.5 Chlamydiae yaeT ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 2JFDS@204428,COG4775@1,COG4775@2 NA|NA|NA M membrane OINAGBCE_00476 1444712.BN1013_01074 7.9e-31 140.6 Chlamydiae ompH ko:K06142 ko00000 Bacteria 2JG9X@204428,COG2825@1,COG2825@2 NA|NA|NA M Outer membrane protein (OmpH-like) OINAGBCE_00477 765952.PUV_09930 7.7e-66 257.7 Chlamydiae lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JFPD@204428,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell OINAGBCE_00479 1120965.AUBV01000009_gene3085 9.9e-36 157.5 Bacteria Bacteria 2DNEI@1,32X43@2 NA|NA|NA OINAGBCE_00481 675814.VIC_003829 3.8e-29 134.8 Vibrionales Bacteria 1N1EV@1224,1SAJF@1236,1XXFY@135623,COG0655@1,COG0655@2 NA|NA|NA S COG0655 Multimeric flavodoxin WrbA OINAGBCE_00482 1444711.CCJF01000005_gene1077 1.1e-158 566.6 Chlamydiae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c Bacteria 2JFNB@204428,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family OINAGBCE_00483 264201.pc1236 2.8e-216 758.8 Chlamydiae acpP 2.3.1.40,6.2.1.20 ko:K01909,ko:K02078,ko:K05939 ko00071,ko00564,map00071,map00564 R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 Bacteria 2JFJE@204428,COG0204@1,COG0204@2,COG0236@1,COG0236@2,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme OINAGBCE_00485 765952.PUV_13500 8.1e-30 136.7 Chlamydiae mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2JHHF@204428,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain OINAGBCE_00486 1444711.CCJF01000005_gene1072 2.4e-162 578.6 Chlamydiae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JFJJ@204428,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP OINAGBCE_00487 1444712.BN1013_00923 1.1e-24 119.0 Chlamydiae rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2JGA1@204428,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation OINAGBCE_00488 765952.PUV_13470 1.4e-35 156.4 Chlamydiae nadD 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2JG9K@204428,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) OINAGBCE_00489 1444711.CCJF01000005_gene1067 2.1e-21 109.4 Chlamydiae CP_0952 iHN637.CLJU_RS04615 Bacteria 2JGCK@204428,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase OINAGBCE_00490 765952.PUV_13440 5.4e-104 385.2 Chlamydiae CP_0954 4.2.2.1 ko:K01727 ko00000,ko01000 PL8 Bacteria 2JFK2@204428,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation OINAGBCE_00491 115711.CP_0955 1.6e-117 429.5 Bacteria mqnC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 Bacteria COG1060@1,COG1060@2 NA|NA|NA H 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity OINAGBCE_00492 264201.pc1243 6.3e-103 380.9 Chlamydiae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2JFKY@204428,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) OINAGBCE_00493 1444711.CCJF01000005_gene1671 7.8e-23 112.8 Chlamydiae yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07461 ko00000 Bacteria 2JH7H@204428,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain OINAGBCE_00494 1437425.CSEC_0398 1.8e-133 482.3 Chlamydiae dusC GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 ko:K05541 ko00000,ko01000,ko03016 Bacteria 2JFKN@204428,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines OINAGBCE_00495 247490.KSU1_C0527 2.8e-144 518.5 Planctomycetes copA 1.16.3.3 ko:K22348 ko00000,ko01000 Bacteria 2IX3N@203682,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase OINAGBCE_00496 1444712.BN1013_02346 1e-78 300.8 Chlamydiae copB ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 2JGB1@204428,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein OINAGBCE_00497 756067.MicvaDRAFT_2473 2.1e-06 61.2 Oscillatoriales Bacteria 1G893@1117,1HHRI@1150,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) OINAGBCE_00498 278957.ABEA03000100_gene913 4.9e-48 197.6 Opitutae ko:K07491 ko00000 Bacteria 3K9MH@414999,46XEX@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like OINAGBCE_00499 1437425.CSEC_1269 1.3e-32 147.9 Chlamydiae Bacteria 2JH9U@204428,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) OINAGBCE_00500 1306947.ARQD01000002_gene475 3.3e-21 109.4 Bacteria Bacteria 2DMAR@1,32UGI@2 NA|NA|NA OINAGBCE_00502 331113.SNE_A06840 3e-64 253.1 Chlamydiae bglA 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 Bacteria 2JH6H@204428,COG2723@1,COG2723@2 NA|NA|NA G Glycosyl hydrolase family 1 OINAGBCE_00505 765952.PUV_12790 2.8e-41 175.3 Chlamydiae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2JG53@204428,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions OINAGBCE_00507 264201.pc0802 1.4e-20 105.5 Chlamydiae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2JGB5@204428,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit OINAGBCE_00508 1444711.CCJF01000005_gene1384 6e-71 274.2 Chlamydiae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JFXW@204428,COG0149@1,COG0149@2 NA|NA|NA F Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) OINAGBCE_00509 1444711.CCJF01000005_gene1123 7.1e-19 99.8 Chlamydiae Bacteria 2AKRI@1,2JGD9@204428,31BID@2 NA|NA|NA OINAGBCE_00510 1444711.CCJF01000005_gene130 1e-68 266.5 Chlamydiae gmhA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JFXT@204428,COG0279@1,COG0279@2 NA|NA|NA G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate OINAGBCE_00511 765952.PUV_26760 1.2e-56 227.3 Chlamydiae lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 Bacteria 2JFZS@204428,COG1663@1,COG1663@2 NA|NA|NA F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) OINAGBCE_00512 5722.XP_001312703.1 2e-09 70.9 Eukaryota Eukaryota KOG0588@1,KOG0588@2759 NA|NA|NA T protein serine/threonine kinase activity OINAGBCE_00513 1437425.CSEC_1579 1.5e-168 599.4 Chlamydiae icd 1.1.1.41,1.1.1.42 ko:K00030,ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R00709,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2JFP7@204428,COG0473@1,COG0473@2 NA|NA|NA C Isocitrate/isopropylmalate dehydrogenase OINAGBCE_00514 765952.PUV_01160 1.3e-97 363.2 Chlamydiae kpsF 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_1278 Bacteria 2JFVE@204428,COG0517@1,COG0517@2,COG0794@1,COG0794@2 NA|NA|NA M Belongs to the SIS family. GutQ KpsF subfamily OINAGBCE_00515 1444712.BN1013_01067 1.6e-113 416.4 Chlamydiae aaaT Bacteria 2JFGQ@204428,COG1301@1,COG1301@2 NA|NA|NA C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family OINAGBCE_00517 716544.wcw_1728 1.3e-08 66.6 Chlamydiae Bacteria 2E3CP@1,2JGFA@204428,32YBY@2 NA|NA|NA OINAGBCE_00518 765952.PUV_13750 1.1e-109 403.7 Chlamydiae nhaD Bacteria 2JFN6@204428,COG1055@1,COG1055@2 NA|NA|NA P Na H antiporter OINAGBCE_00519 716544.wcw_1557 7.2e-79 300.8 Chlamydiae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 2JFIY@204428,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil OINAGBCE_00520 1278306.KB906916_gene1142 2.9e-41 174.9 Fusobacteria dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 37A5U@32066,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality OINAGBCE_00521 1437425.CSEC_0168 8.3e-32 142.9 Chlamydiae CP_0026 ko:K06960 ko00000 Bacteria 2JGBY@204428,COG1837@1,COG1837@2 NA|NA|NA S KH domain OINAGBCE_00527 1444711.CCJF01000005_gene839 8e-213 747.3 Chlamydiae Bacteria 2CCDD@1,2JFXI@204428,2Z99Z@2 NA|NA|NA OINAGBCE_00529 1444712.BN1013_01450 6.6e-92 344.0 Chlamydiae kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JFD5@204428,COG2877@1,COG2877@2 NA|NA|NA M Belongs to the KdsA family OINAGBCE_00530 1444711.CCJF01000005_gene843 6.7e-08 64.7 Chlamydiae Bacteria 2ETBM@1,2JGJI@204428,33KVJ@2 NA|NA|NA OINAGBCE_00532 716544.wcw_1548 5.6e-87 327.4 Chlamydiae lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 2JFFD@204428,COG1137@1,COG1137@2 NA|NA|NA S ABC transporter OINAGBCE_00533 1444711.CCJF01000005_gene1324 5.9e-43 181.8 Chlamydiae 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 2JGBP@204428,COG0631@1,COG0631@2 NA|NA|NA T Protein phosphatase 2C OINAGBCE_00538 716544.wcw_0556 3.6e-199 701.4 Chlamydiae ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2JFI6@204428,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter C-terminal domain OINAGBCE_00539 626418.bglu_2g01090 2.4e-92 346.7 Burkholderiaceae 3.1.4.3 ko:K01114 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919 R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko01000,ko02042 Bacteria 1K2NJ@119060,1MWVP@1224,2VMZ4@28216,COG3511@1,COG3511@2,COG3540@1,COG3540@2 NA|NA|NA M PFAM phosphoesterase OINAGBCE_00540 1444711.CCJF01000005_gene1157 5.5e-58 230.7 Chlamydiae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2JG2B@204428,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides OINAGBCE_00541 716544.wcw_0649 1.3e-38 166.8 Chlamydiae ko:K09807 ko00000 Bacteria 2JGAJ@204428,COG2968@1,COG2968@2 NA|NA|NA S Protein of unknown function (DUF541) OINAGBCE_00543 1444711.CCJF01000005_gene360 6.4e-79 300.4 Chlamydiae can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273,iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Bacteria 2JGJ5@204428,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide OINAGBCE_00544 264201.pc1072 7.7e-45 188.0 Chlamydiae holB 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JGB3@204428,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III OINAGBCE_00548 331113.SNE_A14090 4e-49 201.4 Chlamydiae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2JG2V@204428,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis OINAGBCE_00549 264201.pc1074 0.0 1219.1 Chlamydiae gyrA 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2JFMG@204428,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner OINAGBCE_00550 1444711.CCJF01000005_gene1235 0.0 1170.2 Chlamydiae gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2JFF2@204428,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner OINAGBCE_00551 331113.SNE_A14120 2.4e-18 98.2 Chlamydiae 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JGEC@204428,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) OINAGBCE_00552 1444712.BN1013_00630 6.3e-35 153.3 Chlamydiae mazF ko:K07171 ko00000,ko01000,ko02048 Bacteria 2JHEQ@204428,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module OINAGBCE_00553 1444712.BN1013_00631 1.4e-16 92.0 Bacteria mazE ko:K07172,ko:K18842 ko00000,ko02048 Bacteria COG2336@1,COG2336@2 NA|NA|NA T PFAM SpoVT AbrB OINAGBCE_00554 765952.PUV_12510 2e-202 712.2 Chlamydiae gldK Bacteria 2JFPX@204428,COG0515@1,COG0515@2,COG1262@1,COG1262@2 NA|NA|NA KLT Together with the serine threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth OINAGBCE_00556 1444712.BN1013_01837 2.2e-186 659.1 Chlamydiae yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2JFUV@204428,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins OINAGBCE_00557 1444711.CCJF01000005_gene1227 1.5e-128 466.5 Chlamydiae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2JFG5@204428,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids OINAGBCE_00558 1444711.CCJF01000005_gene520 2.6e-44 186.4 Chlamydiae Bacteria 2JFI5@204428,COG4641@1,COG4641@2 NA|NA|NA S Glycosyl transferases group 1 OINAGBCE_00560 1444712.BN1013_02328 6.1e-91 340.9 Chlamydiae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 2JFUN@204428,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 OINAGBCE_00561 1437425.CSEC_0453 4.4e-24 119.0 Chlamydiae Bacteria 2ARN8@1,2JG6N@204428,31GYX@2 NA|NA|NA OINAGBCE_00565 1444712.BN1013_01165 3.2e-30 139.0 Chlamydiae citB 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2JH47@204428,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon OINAGBCE_00567 1444711.CCJF01000005_gene1677 3.2e-210 738.8 Chlamydiae acsA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JFRM@204428,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA OINAGBCE_00568 331113.SNE_B25120 1.2e-11 76.3 Chlamydiae nudA Bacteria 2JHDU@204428,COG4043@1,COG4043@2 NA|NA|NA OINAGBCE_00570 331113.SNE_B25120 1.5e-11 77.0 Chlamydiae nudA Bacteria 2JHDU@204428,COG4043@1,COG4043@2 NA|NA|NA OINAGBCE_00572 332101.JIBU02000053_gene3523 1.6e-75 290.0 Clostridiaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,247M9@186801,36DGP@31979,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family OINAGBCE_00575 716544.wcw_1214 8.3e-137 493.8 Chlamydiae hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 2JFU8@204428,COG0001@1,COG0001@2 NA|NA|NA H Glutamate-1-semialdehyde OINAGBCE_00576 765952.PUV_20070 2e-137 496.1 Chlamydiae ko:K07403 ko00000 Bacteria 2JFGV@204428,COG1030@1,COG1030@2 NA|NA|NA O NfeD-like C-terminal, partner-binding OINAGBCE_00577 1444711.CCJF01000005_gene1315 1.9e-19 102.4 Chlamydiae nfeD ko:K07403 ko00000 Bacteria 2JGCN@204428,COG1030@1,COG1030@2 NA|NA|NA O NfeD-like C-terminal, partner-binding OINAGBCE_00578 331113.SNE_A10910 4.3e-122 444.5 Chlamydiae yqfA Bacteria 2JFGA@204428,COG4864@1,COG4864@2 NA|NA|NA S SigmaW regulon antibacterial OINAGBCE_00580 765952.PUV_20020 1.5e-46 193.0 Chlamydiae yggS ko:K06997 ko00000 Bacteria 2JG46@204428,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis OINAGBCE_00582 765952.PUV_02970 2.7e-10 73.2 Chlamydiae ko:K06889 ko00000 Bacteria 2JH9P@204428,COG1073@1,COG1073@2 NA|NA|NA S Chlamydia CHLPS protein (DUF818) OINAGBCE_00583 765952.PUV_02980 7.6e-14 85.1 Chlamydiae ko:K06889 ko00000 Bacteria 2JH9P@204428,COG1073@1,COG1073@2 NA|NA|NA S Chlamydia CHLPS protein (DUF818) OINAGBCE_00584 349161.Dred_1395 7.5e-34 151.4 Clostridia fcl 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 R05692 RC01014 ko00000,ko00001,ko01000 Bacteria 1TQV2@1239,249R2@186801,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction OINAGBCE_00586 765952.PUV_05590 1.1e-67 264.2 Bacteria Bacteria COG0654@1,COG0654@2 NA|NA|NA CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases OINAGBCE_00589 1230343.CANP01000040_gene3047 1.2e-12 79.7 Legionellales Bacteria 1JDV8@118969,1P17J@1224,1SSIP@1236,2C03C@1,34925@2 NA|NA|NA OINAGBCE_00590 583355.Caka_1478 5.7e-272 944.1 Opitutae nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 3K76K@414999,46SFJ@74201,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides OINAGBCE_00591 794903.OPIT5_13510 1.7e-106 392.9 Opitutae nrdB 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iJN746.PP_1177 Bacteria 3K7VI@414999,46SMW@74201,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides OINAGBCE_00592 264201.pc1715 1.8e-124 453.0 Chlamydiae putP ko:K03307,ko:K11928 ko00000,ko02000 2.A.21,2.A.21.2 Bacteria 2JFMA@204428,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family OINAGBCE_00594 580340.Tlie_1806 3e-14 84.3 Bacteria ko:K06218 ko00000,ko02048 Bacteria COG2026@1,COG2026@2 NA|NA|NA DJ nuclease activity OINAGBCE_00595 1444712.BN1013_01712 1e-88 334.3 Bacteria CP_0465 Bacteria COG3202@1,COG3202@2 NA|NA|NA C ATP:ADP antiporter activity OINAGBCE_00596 1444711.CCJF01000005_gene1342 2.8e-126 458.4 Chlamydiae trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 2JFQH@204428,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family OINAGBCE_00597 1444711.CCJF01000005_gene1343 1.7e-20 106.7 Chlamydiae Bacteria 2CP5R@1,2JGYC@204428,33T3X@2 NA|NA|NA OINAGBCE_00598 1444711.CCJF01000005_gene736 1e-104 387.5 Chlamydiae oppA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2JFE2@204428,COG4166@1,COG4166@2 NA|NA|NA E peptide ABC transporter, periplasmic OINAGBCE_00599 765952.PUV_13710 5e-17 94.7 Chlamydiae Bacteria 2E3XS@1,2JGEP@204428,32YUT@2 NA|NA|NA OINAGBCE_00601 1444711.CCJF01000005_gene1273 2.1e-112 412.5 Chlamydiae rlmI GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 2JGMG@204428,COG1092@1,COG1092@2 NA|NA|NA J S-adenosylmethionine-dependent methyltransferase OINAGBCE_00603 1437425.CSEC_1250 1.1e-58 233.0 Chlamydiae erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2JFY5@204428,COG0316@1,COG0316@2 NA|NA|NA S Domain of unknown function (DUF1858) OINAGBCE_00604 716544.wcw_1001 2.8e-28 131.0 Chlamydiae fdxC ko:K04755,ko:K11107 ko00000 Bacteria 2JGBJ@204428,COG0633@1,COG0633@2 NA|NA|NA C 2Fe-2S iron-sulfur cluster binding domain OINAGBCE_00605 716544.wcw_1035 2.6e-246 858.2 Chlamydiae CP_0242 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 2JFEB@204428,COG4692@1,COG4692@2 NA|NA|NA G Protein of unknown function (DUF3604) OINAGBCE_00607 237368.SCABRO_00286 5.7e-26 124.0 Planctomycetes Bacteria 2J0J0@203682,COG0614@1,COG0614@2 NA|NA|NA P PD-(D/E)XK nuclease superfamily OINAGBCE_00608 264201.pc1822 1.1e-72 280.8 Chlamydiae CP_0268 ko:K03307 ko00000 2.A.21 Bacteria 2JGYB@204428,COG0591@1,COG0591@2 NA|NA|NA E Sodium:solute symporter family OINAGBCE_00609 1444711.CCJF01000005_gene136 2.6e-88 332.0 Chlamydiae spoU 2.1.1.185,2.1.1.208 ko:K03218,ko:K03437,ko:K21514 ko00000,ko01000,ko03009,ko03016 Bacteria 2JFQK@204428,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family OINAGBCE_00610 765952.PUV_26930 5.8e-51 207.6 Chlamydiae 5.4.99.23,5.4.99.24 ko:K06179,ko:K06180 ko00000,ko01000,ko03009 Bacteria 2JG1U@204428,COG0564@1,COG0564@2 NA|NA|NA J RNA pseudouridylate synthase OINAGBCE_00611 933262.AXAM01000014_gene229 3.4e-106 392.1 Proteobacteria ko:K07133 ko00000 Bacteria 1MWDX@1224,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily) OINAGBCE_00614 1444712.BN1013_00959 1.3e-91 343.6 Chlamydiae dacC 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2JFGM@204428,COG1686@1,COG1686@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase OINAGBCE_00615 716544.wcw_1520 1.6e-33 149.1 Chlamydiae CP_0076 Bacteria 2E7DZ@1,2JGFH@204428,331X1@2 NA|NA|NA OINAGBCE_00616 1121447.JONL01000010_gene2435 2.7e-100 372.5 Desulfovibrionales umuC 2.7.7.7 ko:K02346,ko:K03502 ko00000,ko01000,ko03400 Bacteria 1MUUH@1224,2M84T@213115,2WJXN@28221,42NJ4@68525,COG0389@1,COG0389@2 NA|NA|NA L PFAM UMUC domain protein DNA-repair protein OINAGBCE_00617 331113.SNE_A13170 4.3e-33 147.5 Chlamydiae umuD ko:K03503 ko00000,ko01000,ko01002,ko03400 Bacteria 2JG8X@204428,COG1974@1,COG1974@2 NA|NA|NA L Peptidase S24-like OINAGBCE_00620 1444711.CCJF01000005_gene680 5.6e-210 737.3 Chlamydiae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 2JFGE@204428,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase OINAGBCE_00621 1444712.BN1013_00015 8.8e-88 330.1 Chlamydiae CP_0089 Bacteria 28M7J@1,2JFRK@204428,2ZAKZ@2 NA|NA|NA S Protein of unknown function (DUF2709) OINAGBCE_00622 1444712.BN1013_00013 1.2e-50 206.5 Chlamydiae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 2JG1C@204428,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation OINAGBCE_00623 1444711.CCJF01000005_gene689 2.3e-91 342.0 Chlamydiae dnaQ_2 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JFW8@204428,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III, epsilon OINAGBCE_00624 264201.pc1822 1.2e-43 184.5 Chlamydiae CP_0268 ko:K03307 ko00000 2.A.21 Bacteria 2JGYB@204428,COG0591@1,COG0591@2 NA|NA|NA E Sodium:solute symporter family OINAGBCE_00625 765952.PUV_24700 6.3e-128 464.2 Chlamydiae pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSbBS512_1146.SbBS512_E3351 Bacteria 2JFK3@204428,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family OINAGBCE_00626 1444712.BN1013_00006 1.4e-162 579.7 Chlamydiae tlcA_2 ko:K03301 ko00000 2.A.12 Bacteria 2JFQD@204428,COG3202@1,COG3202@2 NA|NA|NA P ADP,ATP carrier protein OINAGBCE_00627 1444711.CCJF01000005_gene697 3.5e-150 538.5 Chlamydiae tlcA_2 ko:K03301 ko00000 2.A.12 Bacteria 2JFSE@204428,COG3202@1,COG3202@2 NA|NA|NA P TLC ATP/ADP transporter OINAGBCE_00628 51511.ENSCSAVP00000016501 3.8e-16 92.8 Chordata TSSK6 GO:0000003,GO:0000166,GO:0000287,GO:0003006,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006323,GO:0006325,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0006997,GO:0007154,GO:0007165,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007289,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019538,GO:0019953,GO:0022412,GO:0022414,GO:0023052,GO:0030154,GO:0030554,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0035092,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0044703,GO:0046872,GO:0048232,GO:0048468,GO:0048515,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051276,GO:0051704,GO:0051716,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.1 ko:K08811 ko00000,ko01000,ko01001,ko03036 Metazoa 38D83@33154,3B949@33208,3CVU6@33213,4816W@7711,KOG0583@1,KOG0583@2759 NA|NA|NA T Belongs to the protein kinase superfamily OINAGBCE_00629 1437425.CSEC_1950 6.5e-26 124.0 Chlamydiae pgsA_1 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2JG6R@204428,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family OINAGBCE_00630 765952.PUV_03590 6.2e-34 151.0 Chlamydiae dedA Bacteria 2JG5K@204428,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein OINAGBCE_00631 1444712.BN1013_00518 1e-63 250.8 Chlamydiae ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K16052 ko00000,ko02000 1.A.23.4 Bacteria 2JFYU@204428,COG0668@1,COG0668@2 NA|NA|NA M Mechanosensitive ion channel OINAGBCE_00632 1444712.BN1013_00549 2.4e-75 289.3 Chlamydiae sppA ko:K04773,ko:K21511 ko00000,ko01000,ko01002 Bacteria 2JFFW@204428,COG0616@1,COG0616@2 NA|NA|NA OU Peptidase family S49 OINAGBCE_00633 1444711.CCJF01000005_gene666 8.2e-293 1013.1 Chlamydiae polA GO:0000287,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004536,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006284,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0017108,GO:0018130,GO:0019438,GO:0019439,GO:0022616,GO:0030312,GO:0030955,GO:0031420,GO:0033554,GO:0033567,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048256,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576 2.7.7.7,3.1.26.4 ko:K01146,ko:K02335,ko:K03469 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2JFW6@204428,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity OINAGBCE_00634 765952.PUV_06680 3.6e-39 168.3 Chlamydiae coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,3.2.2.23,4.2.99.18,5.4.99.23 ko:K00859,ko:K06180,ko:K10563 ko00770,ko01100,ko03410,map00770,map01100,map03410 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko03009,ko03400 Bacteria 2JG5A@204428,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A OINAGBCE_00635 264201.pc0221 7.4e-205 719.9 Chlamydiae rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 2JFQF@204428,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template OINAGBCE_00637 639282.DEFDS_1845 8.3e-51 206.5 Deferribacteres Bacteria 2GFEU@200930,COG0432@1,COG0432@2 NA|NA|NA S Uncharacterised protein family UPF0047 OINAGBCE_00639 765952.PUV_06750 5.5e-117 427.6 Chlamydiae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2JFKD@204428,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control OINAGBCE_00640 1229831.M832_00320 1.3e-27 128.6 Chlamydiae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG9Q@204428,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family OINAGBCE_00641 716544.wcw_1651 3.3e-20 104.4 Chlamydiae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGD4@204428,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 OINAGBCE_00645 1444712.BN1013_00535 4e-135 488.8 Chlamydiae prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 2JFDY@204428,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family OINAGBCE_00646 1444712.BN1013_00534 1.7e-18 99.8 Chlamydiae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 2JG8K@204428,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves OINAGBCE_00647 264201.pc0210 5.1e-45 187.6 Chlamydiae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 2JG62@204428,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves OINAGBCE_00648 1437425.CSEC_2002 7.1e-54 216.5 Chlamydiae rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG35@204428,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit OINAGBCE_00649 1444711.CCJF01000005_gene652 5e-68 263.8 Chlamydiae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFZ4@204428,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA OINAGBCE_00650 1444711.CCJF01000005_gene651 0.0 1082.0 Chlamydiae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2JFJN@204428,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome OINAGBCE_00651 1444711.CCJF01000005_gene650 1.1e-40 172.9 Chlamydiae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG78@204428,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes OINAGBCE_00653 1444711.CCJF01000005_gene605 2.4e-25 122.1 Chlamydiae Bacteria 2CDQ1@1,2JG96@204428,32TFM@2 NA|NA|NA OINAGBCE_00654 1444711.CCJF01000005_gene604 2.7e-136 491.9 Chlamydiae mrdB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K05837 ko00000,ko03036 Bacteria 2JFPV@204428,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family OINAGBCE_00655 765952.PUV_06570 2.7e-36 159.1 Chlamydiae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 iLJ478.TM0224 Bacteria 2JG7M@204428,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family OINAGBCE_00659 335543.Sfum_1288 2.5e-106 392.5 Syntrophobacterales rmuC ko:K09760 ko00000 Bacteria 1MWHV@1224,2MQKI@213462,2WJDE@28221,42NDS@68525,COG1322@1,COG1322@2 NA|NA|NA S RmuC family OINAGBCE_00660 1444711.CCJF01000005_gene1026 5.7e-38 164.5 Chlamydiae Bacteria 2JG7H@204428,COG3907@1,COG3907@2 NA|NA|NA S Acid phosphatase homologues OINAGBCE_00661 861299.J421_3366 3e-18 99.0 Gemmatimonadetes lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1ZSSM@142182,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair OINAGBCE_00662 765952.PUV_17140 1.4e-68 266.5 Chlamydiae pssA 2.7.8.5,2.7.8.8 ko:K00995,ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800,R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFMU@204428,COG1183@1,COG1183@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family OINAGBCE_00663 1444711.CCJF01000005_gene1016 4.1e-311 1074.7 Chlamydiae CP_0875 ko:K06972 ko00000,ko01000,ko01002 Bacteria 2JFJS@204428,COG1026@1,COG1026@2 NA|NA|NA S Peptidase M16C associated OINAGBCE_00664 765952.PUV_25990 9.2e-139 500.4 Chlamydiae CP_0876 Bacteria 2JFTI@204428,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain OINAGBCE_00665 665571.STHERM_c19310 1.9e-49 202.2 Spirochaetes tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 2J8GN@203691,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides OINAGBCE_00666 1444711.CCJF01000004_gene1950 8.3e-158 563.9 Chlamydiae ybaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03455 ko00000 2.A.37 Bacteria 2JFJP@204428,COG1226@1,COG1226@2,COG4651@1,COG4651@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family OINAGBCE_00667 1444711.CCJF01000005_gene480 1.5e-26 125.6 Bacteria Bacteria 2E3V1@1,32YSA@2 NA|NA|NA OINAGBCE_00668 1353529.M899_2142 5.9e-24 117.5 Deltaproteobacteria sprT Bacteria 1R1VA@1224,2X8HF@28221,43DBF@68525,COG3091@1,COG3091@2 NA|NA|NA S Protein of unknown function (DUF2786) OINAGBCE_00669 716544.wcw_0019 9.2e-23 113.2 Bacteria 2.3.2.29,2.5.1.18,3.8.1.2 ko:K00799,ko:K01560,ko:K09705,ko:K21420 ko00361,ko00480,ko00625,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00625,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418 R03522,R05287,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11547,R11548,R11905 RC00004,RC00064,RC00069,RC00697,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria COG3502@1,COG3502@2 NA|NA|NA S Protein of unknown function (DUF952) OINAGBCE_00670 765952.PUV_03850 2.1e-101 376.3 Bacteria Bacteria COG2072@1,COG2072@2 NA|NA|NA P N,N-dimethylaniline monooxygenase activity OINAGBCE_00671 765952.PUV_11040 9.8e-115 419.9 Chlamydiae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 2JFUA@204428,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine OINAGBCE_00672 716544.wcw_1071 2.7e-73 282.0 Chlamydiae 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2JFYF@204428,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family OINAGBCE_00673 716544.wcw_0324 4.6e-13 82.4 Chlamydiae Bacteria 2JGD8@204428,COG1075@1,COG1075@2 NA|NA|NA S Lipase (class 2) OINAGBCE_00674 32264.tetur25g00730.1 7.8e-07 61.2 Arthropoda GO:0000003,GO:0000165,GO:0000188,GO:0001654,GO:0001667,GO:0001700,GO:0001736,GO:0001738,GO:0001932,GO:0001933,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002682,GO:0002684,GO:0002790,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0006464,GO:0006468,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0006950,GO:0006979,GO:0006996,GO:0007010,GO:0007154,GO:0007164,GO:0007165,GO:0007254,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007304,GO:0007306,GO:0007346,GO:0007368,GO:0007389,GO:0007391,GO:0007399,GO:0007422,GO:0007423,GO:0007439,GO:0007441,GO:0007444,GO:0007483,GO:0007484,GO:0007485,GO:0007548,GO:0007552,GO:0007560,GO:0007561,GO:0007568,GO:0008104,GO:0008138,GO:0008150,GO:0008152,GO:0008340,GO:0008362,GO:0008544,GO:0008579,GO:0009306,GO:0009611,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009799,GO:0009855,GO:0009886,GO:0009887,GO:0009888,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010259,GO:0010389,GO:0010468,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010631,GO:0010632,GO:0010634,GO:0010646,GO:0010648,GO:0010720,GO:0010927,GO:0010941,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016310,GO:0016311,GO:0016331,GO:0016477,GO:0016787,GO:0016788,GO:0016791,GO:0017017,GO:0019220,GO:0019222,GO:0019538,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023014,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030154,GO:0030334,GO:0030335,GO:0030539,GO:0030703,GO:0030707,GO:0030855,GO:0030856,GO:0030858,GO:0031098,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032872,GO:0032873,GO:0032879,GO:0032940,GO:0032989,GO:0033036,GO:0033549,GO:0033554,GO:0033673,GO:0034599,GO:0035112,GO:0035126,GO:0035215,GO:0035239,GO:0035295,GO:0035335,GO:0035556,GO:0036211,GO:0040003,GO:0040011,GO:0040012,GO:0040017,GO:0042060,GO:0042221,GO:0042325,GO:0042326,GO:0042335,GO:0042578,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043412,GO:0043549,GO:0043900,GO:0043902,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045184,GO:0045595,GO:0045597,GO:0045859,GO:0045936,GO:0046328,GO:0046329,GO:0046528,GO:0046529,GO:0046661,GO:0046843,GO:0046844,GO:0046903,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048546,GO:0048557,GO:0048562,GO:0048563,GO:0048565,GO:0048566,GO:0048567,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048608,GO:0048609,GO:0048611,GO:0048613,GO:0048615,GO:0048646,GO:0048707,GO:0048729,GO:0048731,GO:0048749,GO:0048803,GO:0048805,GO:0048806,GO:0048808,GO:0048856,GO:0048869,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051338,GO:0051348,GO:0051403,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0055123,GO:0060255,GO:0060284,GO:0060429,GO:0060548,GO:0060562,GO:0061458,GO:0065007,GO:0065009,GO:0070302,GO:0070303,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071900,GO:0071901,GO:0071907,GO:0080090,GO:0080134,GO:0080135,GO:0090130,GO:0090132,GO:0090598,GO:0140096,GO:1901564,GO:1901987,GO:1901990,GO:1902531,GO:1902532,GO:1902749,GO:1903684,GO:1903688,GO:1905879,GO:1905881,GO:2000026,GO:2000145,GO:2000147,GO:2000241,GO:2000243 3.1.3.16,3.1.3.48 ko:K20216 ko04010,ko04013,ko04214,map04010,map04013,map04214 ko00000,ko00001,ko01000,ko01009 Arthropoda 3A80F@33154,3BT4D@33208,3D9V8@33213,42A4R@6656,COG2453@1,KOG1716@2759 NA|NA|NA V phosphatase activity. It is involved in the biological process described with protein dephosphorylation OINAGBCE_00675 1437425.CSEC_0330 2.4e-147 528.9 Chlamydiae mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 2JFV1@204428,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter OINAGBCE_00677 1303518.CCALI_02246 1.1e-90 340.5 Bacteria 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria COG2730@1,COG2730@2 NA|NA|NA G polysaccharide catabolic process OINAGBCE_00678 443218.AS9A_2778 6.2e-117 427.6 Actinobacteria 1.13.11.52 ko:K00463 ko00380,ko01100,ko05143,map00380,map01100,map05143 M00038 R00678,R02702,R02909,R03628 RC00356 ko00000,ko00001,ko00002,ko01000 Bacteria 2HH9U@201174,COG5274@1,COG5274@2 NA|NA|NA CI Indoleamine 2,3-dioxygenase OINAGBCE_00679 331113.SNE_A15330 7.7e-73 281.2 Chlamydiae CP_0263 Bacteria 2DM90@1,2JGUS@204428,327AV@2 NA|NA|NA S Protein of unknown function (DUF1207) OINAGBCE_00681 1408444.JHYC01000018_gene307 6e-80 304.7 Legionellales Bacteria 1JDMK@118969,1MWBN@1224,1RPD0@1236,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family OINAGBCE_00688 331113.SNE_A00770 1.5e-34 152.9 Chlamydiae Bacteria 2EQNW@1,2JGJ8@204428,33I8U@2 NA|NA|NA OINAGBCE_00689 264201.pc0739 1.3e-201 711.1 Chlamydiae wapA_2 Bacteria 2JFH5@204428,COG3209@1,COG3209@2 NA|NA|NA M Rhs family OINAGBCE_00690 765952.PUV_20480 2e-117 429.1 Chlamydiae pseB 4.2.1.115 ko:K15894 ko00520,map00520 R09697 RC02609 ko00000,ko00001,ko01000 Bacteria 2JFWV@204428,COG1086@1,COG1086@2 NA|NA|NA M Polysaccharide biosynthesis protein OINAGBCE_00691 1444711.CCJF01000005_gene828 4.1e-72 278.5 Chlamydiae hemA GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 ko:K02407,ko:K02492 ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000,ko02035 Bacteria 2JFNX@204428,COG0373@1,COG0373@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) OINAGBCE_00692 1027273.GZ77_12925 9.6e-09 68.2 Oceanospirillales 3.1.4.12 ko:K01117 ko00600,ko01100,map00600,map01100 R02541 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1R4CZ@1224,1S1BM@1236,1XQP9@135619,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family OINAGBCE_00694 264201.pc0088 5.9e-46 191.8 Chlamydiae Bacteria 2JFI5@204428,COG4641@1,COG4641@2 NA|NA|NA S Glycosyl transferases group 1 OINAGBCE_00695 78898.MVEG_11627T0 2.9e-18 99.4 Fungi incertae sedis 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Fungi 1GWMQ@112252,2RXRP@2759,3A0J6@33154,3P1XZ@4751,COG2820@1 NA|NA|NA F Phosphorylase superfamily OINAGBCE_00696 78898.MVEG_11627T0 1.7e-21 110.2 Fungi incertae sedis 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Fungi 1GWMQ@112252,2RXRP@2759,3A0J6@33154,3P1XZ@4751,COG2820@1 NA|NA|NA F Phosphorylase superfamily OINAGBCE_00697 1444711.CCJF01000005_gene871 1.1e-111 410.2 Chlamydiae pseC 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 2JFV9@204428,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family OINAGBCE_00698 765952.PUV_10570 1.9e-30 140.2 Chlamydiae Bacteria 2JG0A@204428,COG0457@1,COG0457@2 NA|NA|NA S tRNA 3'-trailer cleavage OINAGBCE_00699 765952.PUV_22670 5.6e-176 624.0 Chlamydiae dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837,GO:2000112 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2JFNG@204428,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids OINAGBCE_00701 1444711.CCJF01000005_gene867 9e-42 177.2 Chlamydiae comF Bacteria 2JGCT@204428,COG1040@1,COG1040@2 NA|NA|NA S competence protein OINAGBCE_00704 765952.PUV_02400 9.1e-23 112.8 Chlamydiae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2JG9F@204428,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein OINAGBCE_00705 765952.PUV_02380 2.4e-44 185.7 Chlamydiae Bacteria 2BM0T@1,2JG26@204428,32FHQ@2 NA|NA|NA S Carbohydrate family 9 binding domain-like OINAGBCE_00706 1444711.CCJF01000004_gene1899 1.1e-152 547.4 Chlamydiae CP_0319 Bacteria 28JYE@1,2JFF3@204428,2Z9NP@2 NA|NA|NA OINAGBCE_00708 716544.wcw_0789 3.2e-29 135.6 Chlamydiae lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 2JG15@204428,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family OINAGBCE_00709 1444711.CCJF01000004_gene1893 4e-14 85.1 Chlamydiae Bacteria 2C4SM@1,2JG9U@204428,32RNY@2 NA|NA|NA OINAGBCE_00710 1444712.BN1013_00162 9e-61 240.4 Chlamydiae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2JFR9@204428,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism OINAGBCE_00711 765952.PUV_04700 1e-158 566.6 Chlamydiae radA ko:K04485 ko00000,ko03400 Bacteria 2JFUU@204428,COG1066@1,COG1066@2 NA|NA|NA L DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function OINAGBCE_00712 264201.pc0272 1.7e-50 206.1 Chlamydiae hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849 Bacteria 2JFY0@204428,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps OINAGBCE_00713 264201.pc0271 7.6e-29 134.0 Chlamydiae hemD 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 Bacteria 2JGZZ@204428,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase HemD OINAGBCE_00717 1437425.CSEC_0833 1.6e-42 179.9 Chlamydiae Bacteria 2AI7H@1,2JG5W@204428,318MW@2 NA|NA|NA OINAGBCE_00718 765952.PUV_13770 4.7e-27 128.3 Chlamydiae Bacteria 2JGKX@204428,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase family 92 OINAGBCE_00719 1444712.BN1013_02260 3.2e-60 239.2 Chlamydiae Bacteria 2JG4U@204428,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase family 92 OINAGBCE_00720 272947.RP689 1.3e-35 156.8 Rickettsiales licD ko:K07271 ko00000,ko01000 Bacteria 1NPEH@1224,2VF8K@28211,47FUD@766,COG3475@1,COG3475@2 NA|NA|NA M transferase activity OINAGBCE_00721 716544.wcw_0798 1.5e-42 179.5 Chlamydiae noeI ko:K21402 ko00000,ko01000 Bacteria 2JHHJ@204428,COG0275@1,COG0275@2 NA|NA|NA M Putative rRNA methylase OINAGBCE_00723 1444711.CCJF01000004_gene2463 1.9e-36 160.6 Chlamydiae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JG6T@204428,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) OINAGBCE_00724 1444712.BN1013_01684 2.7e-59 235.0 Chlamydiae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2JG36@204428,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins OINAGBCE_00725 716544.wcw_0916 4.5e-37 160.6 Chlamydiae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG6Y@204428,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit OINAGBCE_00726 1444712.BN1013_01687 3.8e-113 414.8 Chlamydiae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFFZ@204428,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily OINAGBCE_00727 1444711.CCJF01000004_gene2468 1.6e-59 236.5 Chlamydiae rluC 5.4.99.23,5.4.99.24 ko:K06179,ko:K06180 ko00000,ko01000,ko03009 Bacteria 2JG7S@204428,COG0564@1,COG0564@2 NA|NA|NA J Pseudouridine synthase OINAGBCE_00728 264201.pc0707 3.9e-78 298.5 Chlamydiae waaC ko:K02841,ko:K02843,ko:K12982 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 2JFJF@204428,COG0859@1,COG0859@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) OINAGBCE_00731 358681.BBR47_13000 3.4e-47 196.4 Paenibacillaceae alkJ 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1UY91@1239,26U16@186822,4HBD1@91061,COG2303@1,COG2303@2 NA|NA|NA E GMC oxidoreductase OINAGBCE_00732 489825.LYNGBM3L_09010 7.2e-98 364.4 Bacteria Bacteria COG1524@1,COG1524@2 NA|NA|NA S mannose-ethanolamine phosphotransferase activity OINAGBCE_00733 9694.XP_007080073.1 1.5e-17 97.8 Carnivora PTPN20B GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005815,GO:0005856,GO:0008150,GO:0009987,GO:0010033,GO:0015630,GO:0031974,GO:0031981,GO:0034097,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0070013,GO:0070887,GO:0071310,GO:0071345 3.1.3.48 ko:K18039 ko00000,ko01000,ko01009 Mammalia 39NCP@33154,3BJPS@33208,3CZPP@33213,3EIMW@33554,3J97X@40674,48BE7@7711,498JF@7742,COG5599@1,KOG0789@2759 NA|NA|NA T Tyrosine-protein phosphatase OINAGBCE_00734 765952.PUV_26470 1.7e-143 516.2 Chlamydiae nuoN GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGSG@204428,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_00735 1444711.CCJF01000004_gene2204 5e-148 531.2 Chlamydiae nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGN8@204428,COG1008@1,COG1008@2 NA|NA|NA C Proton-conducting membrane transporter OINAGBCE_00736 1444711.CCJF01000004_gene2203 4.8e-183 647.9 Chlamydiae nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341,ko:K12137 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Bacteria 2JGEX@204428,COG1009@1,COG1009@2 NA|NA|NA CP NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit OINAGBCE_00737 765952.PUV_26500 2.6e-30 137.9 Chlamydiae nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JH70@204428,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_00738 1444712.BN1013_00363 1.6e-99 369.8 Chlamydiae 1.14.14.1 ko:K00493 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko01000 Bacteria 2JG44@204428,COG0654@1,COG0654@2 NA|NA|NA CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases OINAGBCE_00739 1437425.CSEC_1288 2.7e-61 241.9 Chlamydiae Bacteria 2JFYZ@204428,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family OINAGBCE_00743 331113.SNE_A04330 1.1e-112 413.7 Chlamydiae ko:K07133 ko00000 Bacteria 2JGKT@204428,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_00744 5059.CADAFLAP00008841 3.2e-16 92.0 Eurotiales 1.13.12.4 ko:K00467 ko00620,map00620 R00319 RC01312 ko00000,ko00001,ko01000 Fungi 20G1Z@147545,39GQM@33154,3NVIS@4751,3QKRB@4890,3S3QG@5042,COG1304@1,KOG0538@2759 NA|NA|NA C FMN dependent dehydrogenase OINAGBCE_00745 1437425.CSEC_1385 6.4e-15 87.0 Chlamydiae Bacteria 2CAAA@1,2JH4D@204428,33YHX@2 NA|NA|NA S SnoaL-like domain OINAGBCE_00746 658187.LDG_7243 8.4e-48 196.8 Legionellales ybaK_1 3.4.15.5 ko:K01284 ko00000,ko01000,ko01002 Bacteria 1JDYJ@118969,1RD82@1224,1SASB@1236,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain OINAGBCE_00747 1444712.BN1013_02431 2.1e-66 258.8 Bacteria ydcN GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding OINAGBCE_00750 45351.EDO45781 3.6e-22 112.1 Metazoa Metazoa 2SCGN@2759,3ACHR@33154,3BWMA@33208,COG3475@1 NA|NA|NA M LicD family OINAGBCE_00751 1444711.CCJF01000004_gene1888 1.1e-83 316.2 Chlamydiae sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0010035,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 iNJ661.Rv3846 Bacteria 2JFX8@204428,COG0605@1,COG0605@2 NA|NA|NA C radicals which are normally produced within the cells and which are toxic to biological systems OINAGBCE_00752 264201.pc1105 3.6e-68 264.6 Chlamydiae CP_0368 Bacteria 28KCR@1,2JFPG@204428,2Z9ZJ@2 NA|NA|NA S Tir chaperone protein (CesT) family OINAGBCE_00753 1444712.BN1013_00167 8.9e-111 406.8 Chlamydiae accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 2JFSB@204428,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA OINAGBCE_00754 1444712.BN1013_00168 5e-44 184.1 Chlamydiae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2JG5Q@204428,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA OINAGBCE_00755 1437425.CSEC_0030 8.9e-43 179.9 Chlamydiae 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2JG5P@204428,COG1762@1,COG1762@2 NA|NA|NA G PTS system, IIa OINAGBCE_00756 1444711.CCJF01000004_gene1884 2.5e-60 238.8 Chlamydiae ptsN 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2JG0E@204428,COG1762@1,COG1762@2 NA|NA|NA G PTS system, IIa OINAGBCE_00757 765952.PUV_04840 0.0 1260.4 Chlamydiae clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2JFSM@204428,COG0542@1,COG0542@2 NA|NA|NA O ATP-dependent Clp protease ATP-binding subunit OINAGBCE_00758 1444711.CCJF01000005_gene964 4e-58 231.1 Chlamydiae 2.3.1.128,2.3.1.178 ko:K03790,ko:K03825,ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2JGRB@204428,COG1670@1,COG1670@2 NA|NA|NA J FR47-like protein OINAGBCE_00759 1444712.BN1013_00073 8.8e-128 463.4 Chlamydiae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2JFVB@204428,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA OINAGBCE_00760 5759.rna_EHI_025280-1 3.6e-09 70.1 Amoebozoa ko:K13975 ko05146,map05146 ko00000,ko00001 Eukaryota 3XG3Y@554915,COG0515@1,KOG0192@2759 NA|NA|NA T EGF domain, unclasssified subfamily OINAGBCE_00762 1444711.CCJF01000005_gene895 7.8e-151 541.2 Chlamydiae 2.7.7.64 ko:K12447 ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130 M00014 R00289,R00502,R01381,R03077,R08845 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFIR@204428,COG4284@1,COG4284@2 NA|NA|NA G UTP--glucose-1-phosphate uridylyltransferase OINAGBCE_00763 1437425.CSEC_1377 7.7e-26 122.9 Chlamydiae CP_0171 Bacteria 2JGCA@204428,COG5531@1,COG5531@2 NA|NA|NA B SWI complex, BAF60b domains OINAGBCE_00764 1444712.BN1013_00077 9.8e-86 323.9 Chlamydiae yaeI ko:K07098 ko00000 Bacteria 2JGTA@204428,COG1408@1,COG1408@2 NA|NA|NA S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to form 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipooligosaccharide (LOS) to the outer membrane of the cell OINAGBCE_00765 264201.pc0328 1.2e-73 283.1 Chlamydiae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2JFJC@204428,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs OINAGBCE_00767 1437425.CSEC_0807 7e-36 157.9 Chlamydiae Bacteria 28N6X@1,2JFR2@204428,2ZBBQ@2 NA|NA|NA S Major Facilitator Superfamily OINAGBCE_00769 331113.SNE_A21380 2.7e-78 298.9 Chlamydiae fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,iSB619.SA_RS06010,iSFV_1184.SFV_2325,ic_1306.c4048 Bacteria 2JFG1@204428,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus OINAGBCE_00770 716544.wcw_1508 2e-59 236.1 Chlamydiae lpxA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 iIT341.HP1375,iPC815.YPO1056 Bacteria 2JFJZ@204428,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell OINAGBCE_00771 1444711.CCJF01000004_gene1974 7.3e-56 223.4 Chlamydiae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 2JG3H@204428,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs OINAGBCE_00772 1444711.CCJF01000004_gene1973 2.5e-105 388.7 Chlamydiae fabZ 3.5.1.108,4.2.1.59 ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko01100,ko01212,ko02020,map00061,map00540,map01100,map01212,map02020 M00060,M00083,M00498 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 Bacteria 2JFHE@204428,COG0774@1,COG0774@2 NA|NA|NA F Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis OINAGBCE_00773 1444711.CCJF01000004_gene1943 1.5e-101 376.3 Chlamydiae yceA ko:K07146 ko00000 Bacteria 2JFNW@204428,COG1054@1,COG1054@2 NA|NA|NA S Belongs to the UPF0176 family OINAGBCE_00774 1444711.CCJF01000004_gene1944 9.8e-28 129.4 Chlamydiae trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2JG8T@204428,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family OINAGBCE_00775 716544.wcw_1755 7.5e-44 183.7 Chlamydiae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528,ko:K15256 R10716 RC00003,RC03257 ko00000,ko01000,ko03009,ko03016 Bacteria 2JHHX@204428,COG0030@1,COG0030@2 NA|NA|NA J 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity OINAGBCE_00776 1444712.BN1013_00946 1.2e-46 193.7 Chlamydiae mip 5.2.1.8 ko:K01802,ko:K03773 ko00000,ko01000,ko03110 Bacteria 2JFN0@204428,COG0545@1,COG0545@2 NA|NA|NA M Peptidyl-prolyl cis-trans OINAGBCE_00777 1444711.CCJF01000004_gene1954 1.9e-213 748.8 Chlamydiae aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN678.aspS,iSFV_1184.SFV_1868 Bacteria 2JFKW@204428,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) OINAGBCE_00778 1444711.CCJF01000004_gene1955 1.7e-142 512.7 Chlamydiae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFJ0@204428,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase OINAGBCE_00780 1382359.JIAL01000001_gene2266 1.8e-31 143.7 Acidobacteriia 1.6.5.3,3.4.21.107 ko:K00337,ko:K04771 ko00190,ko01100,ko01503,ko02020,map00190,map01100,map01503,map02020 M00144,M00728 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 3.D.1 Bacteria 2JM8V@204432,3Y7GN@57723,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain OINAGBCE_00781 1444711.CCJF01000004_gene1960 0.0 1550.4 Chlamydiae dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JFDD@204428,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity) OINAGBCE_00784 264201.pc0411 3.5e-09 68.6 Chlamydiae Bacteria 2CAB7@1,2JH3D@204428,33XWY@2 NA|NA|NA OINAGBCE_00785 1444712.BN1013_00974 1.1e-71 276.6 Chlamydiae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFVH@204428,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit OINAGBCE_00786 1444712.BN1013_00975 5.6e-63 247.7 Chlamydiae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG00@204428,COG0088@1,COG0088@2 NA|NA|NA J One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome OINAGBCE_00787 765952.PUV_22990 8e-28 129.8 Chlamydiae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG93@204428,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome OINAGBCE_00788 1444712.BN1013_00977 2.9e-111 408.3 Chlamydiae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFG2@204428,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity OINAGBCE_00789 1437425.CSEC_0218 3.5e-34 150.6 Chlamydiae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG8Y@204428,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA OINAGBCE_00790 716544.wcw_1497 1.5e-31 142.1 Chlamydiae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG6V@204428,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome OINAGBCE_00791 1437425.CSEC_0220 1.1e-89 336.3 Chlamydiae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFW3@204428,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation OINAGBCE_00792 1437425.CSEC_0221 1.3e-59 235.7 Chlamydiae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFZ1@204428,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs OINAGBCE_00794 1444711.CCJF01000004_gene1993 4.5e-21 107.1 Chlamydiae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGE0@204428,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA OINAGBCE_00795 1437425.CSEC_0224 8e-42 176.4 Chlamydiae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG1Q@204428,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome OINAGBCE_00796 1437425.CSEC_0225 1.6e-28 132.1 Chlamydiae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGBU@204428,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit OINAGBCE_00797 765952.PUV_22890 3.1e-72 278.1 Chlamydiae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFGC@204428,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits OINAGBCE_00798 1444711.CCJF01000004_gene1997 9e-39 166.4 Chlamydiae rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG30@204428,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit OINAGBCE_00799 264201.pc0426 9.8e-60 236.5 Chlamydiae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG2H@204428,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center OINAGBCE_00800 1444712.BN1013_00989 6.3e-34 150.2 Chlamydiae rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG9M@204428,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance OINAGBCE_00801 264201.pc0428 7.5e-59 233.4 Chlamydiae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG03@204428,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body OINAGBCE_00802 716544.wcw_1485 2e-39 168.7 Chlamydiae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG4Z@204428,COG0200@1,COG0200@2 NA|NA|NA J binds to the 23S rRNA OINAGBCE_00803 264201.pc0430 7.6e-186 656.8 Chlamydiae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2JFDR@204428,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently OINAGBCE_00804 1444712.BN1013_00993 1.5e-46 192.2 Chlamydiae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG65@204428,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits OINAGBCE_00805 1444711.CCJF01000004_gene2004 2.8e-46 191.4 Chlamydiae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG17@204428,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome OINAGBCE_00806 264201.pc0433 1.1e-134 486.5 Chlamydiae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2JFH2@204428,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates OINAGBCE_00807 264201.pc0434 9.2e-45 186.4 Chlamydiae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG4B@204428,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 OINAGBCE_00809 1444711.CCJF01000004_gene2009 5.9e-143 513.8 Chlamydiae gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 Bacteria 2JFDU@204428,COG0057@1,COG0057@2 NA|NA|NA G Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG OINAGBCE_00810 1444712.BN1013_00998 9.7e-33 147.5 Chlamydiae Bacteria 2A361@1,2JG3F@204428,30RME@2 NA|NA|NA OINAGBCE_00815 1437425.CSEC_1313 9.1e-62 243.4 Chlamydiae Bacteria 2JH3Y@204428,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score OINAGBCE_00816 1437425.CSEC_1314 5.6e-110 404.1 Chlamydiae Bacteria 2JGTP@204428,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system OINAGBCE_00818 570417.WP0261 4.6e-157 561.2 Rickettsiales ko:K06921 ko00000 Bacteria 1MWJX@1224,2V4HQ@28211,47FYU@766,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_00819 1444711.CCJF01000005_gene878 5.4e-36 157.9 Chlamydiae amiA 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 2JG43@204428,COG0860@1,COG0860@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase OINAGBCE_00820 1444711.CCJF01000005_gene877 1.5e-150 539.7 Chlamydiae murE 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFTS@204428,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan OINAGBCE_00821 1444712.BN1013_00043 3e-223 781.6 Chlamydiae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2JFH0@204428,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein OINAGBCE_00822 264201.pc0312 5.5e-15 86.7 Chlamydiae Bacteria 2DQ1W@1,2JGD5@204428,334EN@2 NA|NA|NA OINAGBCE_00823 716544.wcw_0350 1e-63 250.4 Chlamydiae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2JFV8@204428,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA OINAGBCE_00824 1444711.CCJF01000005_gene873 2.8e-39 168.3 Chlamydiae Bacteria 2CIK2@1,2JG72@204428,32QW4@2 NA|NA|NA S Family of unknown function (DUF5399) OINAGBCE_00825 1444711.CCJF01000005_gene872 1.9e-44 185.3 Chlamydiae Bacteria 2JG8H@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_00826 466088.CL42_03650 3.4e-11 74.3 Moraxellaceae Bacteria 1QQBZ@1224,1RSZD@1236,2B0DV@1,31SR7@2,3NRZN@468 NA|NA|NA OINAGBCE_00827 1123053.AUDG01000099_gene1196 2.5e-45 188.7 Proteobacteria Bacteria 1NJAH@1224,2DRSE@1,33CV2@2 NA|NA|NA S Domain of unknown function (DUF4304) OINAGBCE_00828 765952.PUV_20630 1e-108 401.7 Chlamydiae Bacteria 2JFH5@204428,COG3209@1,COG3209@2 NA|NA|NA M Rhs family OINAGBCE_00830 765952.PUV_02970 4.2e-21 109.0 Chlamydiae ko:K06889 ko00000 Bacteria 2JH9P@204428,COG1073@1,COG1073@2 NA|NA|NA S Chlamydia CHLPS protein (DUF818) OINAGBCE_00831 1437425.CSEC_1265 7.5e-23 118.2 Chlamydiae Bacteria 2JG86@204428,COG1196@1,COG1196@2 NA|NA|NA D Protein of unknown function (DUF3638) OINAGBCE_00835 1434325.AZQN01000001_gene374 2.4e-43 181.8 Cytophagia ko:K07071 ko00000 Bacteria 47QN0@768503,4NQJG@976,COG4276@1,COG4276@2 NA|NA|NA S SRPBCC domain-containing protein OINAGBCE_00836 264201.pc1188 5.8e-32 144.1 Chlamydiae tspO ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 9.A.24 Bacteria 2JHAM@204428,COG3476@1,COG3476@2 NA|NA|NA T TspO/MBR family OINAGBCE_00837 1123277.KB893206_gene3246 4.2e-73 281.6 Cytophagia Bacteria 2DBB9@1,2Z86U@2,47JBX@768503,4NI91@976 NA|NA|NA OINAGBCE_00838 504472.Slin_0816 1.2e-225 789.6 Cytophagia ybcC ko:K09822 ko00000 Bacteria 47KWM@768503,4NECE@976,COG3002@1,COG3002@2 NA|NA|NA S Belongs to the UPF0753 family OINAGBCE_00839 1123277.KB893206_gene3248 4.3e-117 428.3 Cytophagia ndhF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00341,ko:K05577,ko:K09822 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 47M8T@768503,4NEBM@976,COG1009@1,COG1009@2 NA|NA|NA CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit OINAGBCE_00840 504472.Slin_0818 1.8e-113 415.6 Bacteroidetes Bacteria 4NXN1@976,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain OINAGBCE_00841 1444711.CCJF01000005_gene1721 1.3e-80 306.2 Chlamydiae fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2JFQC@204428,COG1611@1,COG1611@2 NA|NA|NA S Possible lysine decarboxylase OINAGBCE_00842 925409.KI911562_gene1864 3.6e-35 155.6 Sphingobacteriia ubiA 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1IP3B@117747,4NEE3@976,COG0382@1,COG0382@2 NA|NA|NA H 4-hydroxybenzoate polyprenyltransferase OINAGBCE_00843 1238237.CP10139811_0139 2e-47 195.7 Chlamydiae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186,ko:K16875 ko00130,ko00365,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R10213,R11225 RC00391,RC00814,RC03086,RC03392 ko00000,ko00001,ko00002,ko01000 iAF1260.b2311,iAF987.Gmet_3392,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573 Bacteria 2JH6W@204428,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN OINAGBCE_00844 765952.PUV_19380 9.6e-77 293.5 Chlamydiae yqfU Bacteria 2JFIE@204428,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2179) OINAGBCE_00847 264201.pc0777 9.4e-08 63.5 Chlamydiae Bacteria 2EVWB@1,2JGI1@204428,33PA0@2 NA|NA|NA OINAGBCE_00850 765952.PUV_08130 1.3e-56 226.9 Bacteria Bacteria COG3568@1,COG3568@2 NA|NA|NA N Endonuclease Exonuclease Phosphatase OINAGBCE_00852 331113.SNE_A08750 2.6e-20 104.8 Bacteria rfaG ko:K02844 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT4 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups OINAGBCE_00853 765952.PUV_06580 0.0 1228.0 Chlamydiae ppdK 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2JGR0@204428,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA H Pyruvate phosphate dikinase, PEP/pyruvate binding domain OINAGBCE_00854 264201.pc1581 1.3e-77 296.6 Chlamydiae Bacteria 2DN3U@1,2JGT7@204428,32VCX@2 NA|NA|NA OINAGBCE_00855 1444711.CCJF01000005_gene1680 3.8e-65 255.0 Chlamydiae Bacteria 2AI7H@1,2JG5W@204428,318MW@2 NA|NA|NA OINAGBCE_00856 1444711.CCJF01000005_gene1419 1.9e-48 200.3 Chlamydiae Bacteria 2AI7H@1,2JGWM@204428,33R3U@2 NA|NA|NA OINAGBCE_00857 765952.PUV_25820 1.6e-223 782.3 Chlamydiae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 2JFJR@204428,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source OINAGBCE_00860 1444712.BN1013_00573 3.8e-88 331.6 Chlamydiae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2JFD8@204428,COG0552@1,COG0552@2 NA|NA|NA D Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) OINAGBCE_00861 331113.SNE_A16810 1e-109 403.7 Chlamydiae sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009361,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0042709,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iPC815.YPO1115,iUMNK88_1353.UMNK88_764 Bacteria 2JFW1@204428,COG0045@1,COG0045@2 NA|NA|NA F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit OINAGBCE_00862 765952.PUV_24830 4.6e-120 437.6 Chlamydiae sucD GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iYO844.BSU16100 Bacteria 2JFRV@204428,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit OINAGBCE_00863 1444712.BN1013_00576 1.7e-50 206.8 Chlamydiae Bacteria 2JFYC@204428,COG1994@1,COG1994@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_00864 1121946.AUAX01000005_gene5575 3.2e-19 104.0 Actinobacteria yaeI ko:K07098 ko00000 Bacteria 2I2EP@201174,COG1408@1,COG1408@2 NA|NA|NA S metallophosphoesterase OINAGBCE_00866 331113.SNE_A22960 3.2e-129 468.8 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_00867 452471.Aasi_1795 1.2e-147 529.6 Cytophagia ko:K07133 ko00000 Bacteria 47KTC@768503,4NE39@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_00869 1444712.BN1013_00583 2.8e-125 455.7 Chlamydiae htrA GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2JFTT@204428,COG0265@1,COG0265@2 NA|NA|NA O Periplasmic serine endoprotease DegP-like OINAGBCE_00870 1444711.CCJF01000005_gene795 8.8e-173 613.2 Chlamydiae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2JFSH@204428,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP OINAGBCE_00871 1444711.CCJF01000005_gene796 1.7e-81 308.9 Chlamydiae clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFNY@204428,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins OINAGBCE_00872 765952.PUV_10620 3.1e-59 236.1 Chlamydiae tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 ko:K03545 ko00000 Bacteria 2JG2G@204428,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase OINAGBCE_00874 765952.PUV_10610 0.0 1171.0 Chlamydiae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2JFDP@204428,COG0553@1,COG0553@2 NA|NA|NA KL SNF2 family OINAGBCE_00875 264201.pc1372 5.5e-171 607.1 Chlamydiae mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 2JFNV@204428,COG1077@1,COG1077@2 NA|NA|NA D shape-determining protein MreB OINAGBCE_00876 716544.wcw_1593 4.2e-237 827.4 Chlamydiae pckG GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007028,GO:0007154,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009267,GO:0009410,GO:0009605,GO:0009607,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010106,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016020,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019725,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030003,GO:0030145,GO:0030154,GO:0030312,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031668,GO:0031669,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033554,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0046916,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050792,GO:0050794,GO:0050801,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0075136,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:0098771,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2638 Bacteria 2JFEW@204428,COG1274@1,COG1274@2 NA|NA|NA F Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle OINAGBCE_00877 1444712.BN1013_01412 6.3e-39 168.7 Chlamydiae Bacteria 2JGB6@204428,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif OINAGBCE_00879 1444711.CCJF01000005_gene823 9.2e-75 287.0 Chlamydiae yagE Bacteria 2JG0Z@204428,COG1723@1,COG1723@2 NA|NA|NA S Uncharacterised ACR, YagE family COG1723 OINAGBCE_00880 1532557.JL37_19225 4.7e-09 68.2 Proteobacteria Bacteria 1NPJX@1224,2ENS7@1,33GDC@2 NA|NA|NA OINAGBCE_00881 925775.XVE_4844 1.2e-09 71.6 Gammaproteobacteria Bacteria 1NQ83@1224,1SUP7@1236,29W4S@1,30HPQ@2 NA|NA|NA OINAGBCE_00882 240016.ABIZ01000001_gene3099 2.9e-14 85.1 Bacteria CP_0368 Bacteria 28KCR@1,2Z9ZJ@2 NA|NA|NA S Tir chaperone protein (CesT) family OINAGBCE_00883 400668.Mmwyl1_3683 8.1e-20 103.6 Gammaproteobacteria Bacteria 1N000@1224,1SG3A@1236,COG1247@1,COG1247@2 NA|NA|NA M N-acetyltransferase OINAGBCE_00885 1191299.AJYX01000038_gene3433 6.6e-105 387.5 Vibrionales neuB 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 R01804,R04435 RC00159 ko00000,ko00001,ko01000 Bacteria 1MWG3@1224,1RPIG@1236,1XSC4@135623,COG2089@1,COG2089@2 NA|NA|NA M NeuB family OINAGBCE_00888 1444712.BN1013_01206 0.0 1208.7 Chlamydiae clpB ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2JFW9@204428,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity OINAGBCE_00889 765869.BDW_10315 1.7e-87 330.5 Bdellovibrionales pacS GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1MU08@1224,2MSSV@213481,2WJ4J@28221,42M2R@68525,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase OINAGBCE_00890 1499968.TCA2_3693 1.4e-77 297.0 Paenibacillaceae ampS ko:K19689 ko00000,ko01000,ko01002 Bacteria 1TP65@1239,26RHU@186822,4H9W8@91061,COG2309@1,COG2309@2 NA|NA|NA E peptidase M29 OINAGBCE_00891 331113.SNE_A22230 2.2e-32 147.1 Chlamydiae Bacteria 2JG8P@204428,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) OINAGBCE_00892 331636.G5O_0388 4.7e-25 122.9 Bacteria clsC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 ko:K06132 ko00564,ko01100,map00564,map01100 R11062 RC00017 ko00000,ko00001,ko01000 Bacteria COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol OINAGBCE_00893 716544.wcw_0793 2.1e-40 172.2 Chlamydiae murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFHG@204428,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation OINAGBCE_00894 765952.PUV_10230 1.8e-57 229.6 Chlamydiae trpH 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2JFUH@204428,COG0613@1,COG0613@2 NA|NA|NA S DNA polymerase alpha chain like domain OINAGBCE_00895 984262.SGRA_4042 4.3e-08 68.2 Sphingobacteriia Bacteria 1J102@117747,4NG09@976,COG3291@1,COG3291@2 NA|NA|NA S Fungalysin metallopeptidase (M36) OINAGBCE_00897 497965.Cyan7822_3414 7.1e-10 72.4 Cyanothece Bacteria 1G1EB@1117,3KH9P@43988,COG0515@1,COG0515@2 NA|NA|NA H Serine Threonine protein kinase OINAGBCE_00898 264201.pc0501 9.2e-116 424.1 Chlamydiae Bacteria 2JFP4@204428,COG2939@1,COG2939@2 NA|NA|NA E Serine carboxypeptidase OINAGBCE_00899 1444712.BN1013_00805 5.7e-27 126.3 Chlamydiae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 2JG9T@204428,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex OINAGBCE_00901 1444712.BN1013_00807 6.8e-183 646.7 Chlamydiae tuf GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 iSB619.SA_RS02960 Bacteria 2JFRG@204428,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis OINAGBCE_00903 765952.PUV_19870 2.4e-09 68.2 Chlamydiae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2JGDB@204428,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation OINAGBCE_00904 1444711.CCJF01000004_gene2232 3.6e-70 271.2 Chlamydiae nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2JG0K@204428,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination OINAGBCE_00905 264201.pc0600 6.2e-54 216.9 Chlamydiae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG1I@204428,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors OINAGBCE_00906 1444711.CCJF01000004_gene2234 1.5e-84 319.3 Chlamydiae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFHI@204428,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release OINAGBCE_00907 264201.pc0602 1.4e-47 196.1 Chlamydiae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG7A@204428,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors OINAGBCE_00908 264201.pc0603 5.1e-34 150.6 Chlamydiae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG77@204428,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation OINAGBCE_00909 264201.pc0604 0.0 2096.6 Chlamydiae rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2JFDG@204428,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates OINAGBCE_00913 268407.PWYN_26310 1.2e-63 250.0 Paenibacillaceae ko:K07257 ko00000 Bacteria 1U4YD@1239,26XV6@186822,4HG5W@91061,COG1861@1,COG1861@2 NA|NA|NA M Cytidylyltransferase OINAGBCE_00914 1444712.BN1013_01503 9.4e-29 134.4 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_00915 1437425.CSEC_2034 4.4e-200 704.1 Chlamydiae ybjT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2JFGP@204428,COG0702@1,COG0702@2 NA|NA|NA GM Protein of unknown function (DUF2867) OINAGBCE_00918 765952.PUV_20910 3.8e-35 154.1 Chlamydiae Bacteria 2JH76@204428,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain OINAGBCE_00919 545694.TREPR_1636 2.6e-67 262.3 Spirochaetes Bacteria 2J5IH@203691,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system OINAGBCE_00920 1437425.CSEC_1313 4.2e-22 111.7 Chlamydiae Bacteria 2JH3Y@204428,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score OINAGBCE_00922 1437425.CSEC_0756 1.4e-31 143.7 Chlamydiae Bacteria 2C5CV@1,2JH8V@204428,344ZN@2 NA|NA|NA OINAGBCE_00923 573413.Spirs_2256 6.7e-38 165.6 Spirochaetes Bacteria 28MCF@1,2J6HI@203691,2ZAQK@2 NA|NA|NA OINAGBCE_00925 1122165.AUHS01000005_gene1629 1.5e-126 459.9 Legionellales Bacteria 1JDVP@118969,1MX8F@1224,1RRCQ@1236,COG0659@1,COG0659@2 NA|NA|NA P Sulfate permease family OINAGBCE_00926 716544.wcw_1697 3.1e-36 157.9 Chlamydiae fur ko:K03711,ko:K22297 ko00000,ko03000 Bacteria 2JGEJ@204428,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family OINAGBCE_00928 1216932.CM240_2837 3.2e-09 68.9 Clostridiaceae tam GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c17460,iSDY_1059.SDY_1625,ic_1306.c1942 Bacteria 1V5C5@1239,25B38@186801,36W7R@31979,COG4106@1,COG4106@2 NA|NA|NA S Methionine biosynthesis protein MetW OINAGBCE_00929 244582.JQAK01000001_gene1838 1.3e-24 119.8 Alphaproteobacteria ko:K13614,ko:K15674 ko00000,ko01004,ko01008 Bacteria 1R89Z@1224,2UR2U@28211,COG0454@1,COG0456@2,COG3321@1,COG3321@2 NA|NA|NA Q COG3321 Polyketide synthase modules and related proteins OINAGBCE_00930 1444309.JAQG01000087_gene2646 1.1e-47 198.0 Paenibacillaceae Bacteria 1TSC5@1239,272TG@186822,4HBG5@91061,COG2124@1,COG2124@2 NA|NA|NA Q Cytochrome P450 OINAGBCE_00931 1502850.FG91_00557 3.7e-84 318.9 Sphingomonadales cyp51 1.14.13.70 ko:K05917 ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130 M00101 R05640,R05731 RC01442 ko00000,ko00001,ko00002,ko00199,ko01000 Bacteria 1MV75@1224,2K9F6@204457,2TSV7@28211,COG2124@1,COG2124@2 NA|NA|NA Q Cytochrome P450 OINAGBCE_00934 335283.Neut_1393 3.1e-21 109.0 Nitrosomonadales ko:K06872 ko00000 Bacteria 1PB41@1224,2VMNV@28216,372KU@32003,COG1512@1,COG1512@2 NA|NA|NA S TPM domain OINAGBCE_00936 1444711.CCJF01000004_gene2402 2e-249 869.0 Chlamydiae MA20_43170 ko:K06911 ko00000 Bacteria 2JFFG@204428,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain OINAGBCE_00937 305900.GV64_11000 2.9e-24 120.9 Bacteria 3.1.3.16 ko:K17506,ko:K20074 ko00000,ko01000,ko01009 Bacteria COG0631@1,COG0631@2,COG4886@1,COG4886@2 NA|NA|NA T protein serine/threonine phosphatase activity OINAGBCE_00938 765952.PUV_20120 1.7e-12 80.1 Chlamydiae Bacteria 2JGA2@204428,COG0457@1,COG0457@2 NA|NA|NA S Type III secretion chaperone SycD LcrH OINAGBCE_00940 163908.KB235896_gene1107 5.8e-31 140.6 Nostocales ko:K07065 ko00000 Bacteria 1G6UZ@1117,1HPSM@1161,COG2402@1,COG2402@2 NA|NA|NA S PIN domain OINAGBCE_00942 765952.PUV_12070 2.4e-109 402.5 Chlamydiae astB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009015,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.23 ko:K01484 ko00330,ko01100,map00330,map01100 R04189 RC00024 ko00000,ko00001,ko01000 iECH74115_1262.ECH74115_2463,iECSP_1301.ECSP_2313,iECs_1301.ECs2451,iG2583_1286.G2583_2191 Bacteria 2JFKI@204428,COG3724@1,COG3724@2 NA|NA|NA E Succinylarginine dihydrolase OINAGBCE_00943 157783.LK03_12245 2.9e-132 478.8 Gammaproteobacteria astD GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 R05049 RC00080 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c20030,iEcHS_1320.EcHS_A1829,ic_1306.c2146 Bacteria 1MV2I@1224,1RPQW@1236,COG1012@1,COG1012@2 NA|NA|NA C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate OINAGBCE_00944 1444712.BN1013_01880 1.1e-56 227.3 Chlamydiae astA 1.2.1.71,2.3.1.109 ko:K00673,ko:K06447 ko00330,ko01100,map00330,map01100 R00832,R05049 RC00004,RC00064,RC00080 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_1875 Bacteria 2JG76@204428,COG3138@1,COG3138@2 NA|NA|NA E Arginine N-succinyltransferase beta subunit OINAGBCE_00945 1444711.CCJF01000004_gene2406 2.1e-143 515.8 Chlamydiae lat 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 ko:K00821,ko:K03918,ko:K07250,ko:K13524 ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727 M00016,M00027,M00028,M00845 R00457,R00908,R01648,R02283,R04188,R04475 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv3290c Bacteria 2JFWA@204428,COG0160@1,COG0160@2 NA|NA|NA E Aminotransferase class-III OINAGBCE_00946 765952.PUV_12110 3.1e-101 375.6 Chlamydiae cpg2 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 2JG07@204428,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain OINAGBCE_00947 716544.wcw_0837 8.1e-10 69.3 Chlamydiae Bacteria 2DSAT@1,2JGI6@204428,33F9Y@2 NA|NA|NA OINAGBCE_00948 5762.XP_002673741.1 1.3e-13 83.6 Eukaryota Eukaryota 2RZ0D@2759,COG0778@1 NA|NA|NA C Nitroreductase family OINAGBCE_00952 903818.KI912268_gene1689 6.3e-13 80.1 Bacteria ko:K07133 ko00000 Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily OINAGBCE_00957 765952.PUV_16560 4.7e-124 451.1 Chlamydiae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFCF@204428,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing OINAGBCE_00958 1444712.BN1013_01021 8.7e-36 157.5 Chlamydiae CP_0366 ko:K06381 ko00000 Bacteria 2JG2X@204428,COG2385@1,COG2385@2 NA|NA|NA D Stage II sporulation protein OINAGBCE_00959 1282876.BAOK01000001_gene1290 3.6e-70 271.9 unclassified Alphaproteobacteria yrbG_2 ko:K07301 ko00000,ko02000 2.A.19.5 Bacteria 1MU3R@1224,2TST5@28211,4BQ1D@82117,COG0530@1,COG0530@2 NA|NA|NA P Sodium/calcium exchanger protein OINAGBCE_00966 1444711.CCJF01000004_gene2130 2.7e-70 271.6 Bacteria yfcM GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 ko:K09906 ko00000,ko01000,ko03012 Bacteria COG3101@1,COG3101@2 NA|NA|NA S peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification OINAGBCE_00967 675814.VIC_002896 5.4e-08 64.7 Gammaproteobacteria Bacteria 1RIQF@1224,1SBJ4@1236,2ATAH@1,31ITJ@2 NA|NA|NA OINAGBCE_00968 1444711.CCJF01000004_gene2458 0.0 1089.7 Chlamydiae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01878,ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iJO1366.b3560,iPC815.YPO4072,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,iY75_1357.Y75_RS19360,ic_1306.c4378 Bacteria 2JFPU@204428,COG0751@1,COG0751@2,COG0752@1,COG0752@2 NA|NA|NA J Multifunctional fusion protein OINAGBCE_00969 1437425.CSEC_0512 1e-30 140.6 Chlamydiae wbyL ko:K13002 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 2JFJB@204428,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 OINAGBCE_00971 1444711.CCJF01000004_gene2460 7e-118 430.6 Chlamydiae rlmN 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2JFG3@204428,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs OINAGBCE_00972 1444711.CCJF01000004_gene2462 5.8e-173 614.4 Chlamydiae uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2JFUB@204428,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision OINAGBCE_00973 765952.PUV_19150 4.1e-40 171.0 Chlamydiae CP_0922 Bacteria 2JG88@204428,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function OINAGBCE_00974 1444711.CCJF01000004_gene2357 4.6e-17 94.4 Chlamydiae Bacteria 2DQQX@1,2JGEG@204428,3385Z@2 NA|NA|NA S Domain of unknown function (DUF4339) OINAGBCE_00975 383372.Rcas_4353 3.5e-35 154.5 Chloroflexia Bacteria 2G9KR@200795,377DT@32061,COG0614@1,COG0614@2 NA|NA|NA P PD-(D/E)XK nuclease superfamily OINAGBCE_00976 2342.SOPEG_0453 3.6e-70 271.9 Gammaproteobacteria Bacteria 1MXTN@1224,1RM94@1236,COG3039@1,COG3039@2 NA|NA|NA L ISSoEn1, terminal inverted repeat OINAGBCE_00979 765952.PUV_24180 4.9e-18 97.1 Chlamydiae ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 ko:K06187,ko:K09747 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2JGDH@204428,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection OINAGBCE_00980 1444711.CCJF01000004_gene2063 2.2e-122 446.0 Chlamydiae dnaX 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JFRF@204428,COG2812@1,COG2812@2 NA|NA|NA H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity OINAGBCE_00981 765952.PUV_24140 3.9e-229 801.2 Chlamydiae yqfF ko:K07037 ko00000 Bacteria 2JFF5@204428,COG1480@1,COG1480@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. OINAGBCE_00982 1444712.BN1013_01679 2.3e-46 192.6 Chlamydiae ko:K07124 ko00000 Bacteria 2JG4K@204428,COG0300@1,COG0300@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase OINAGBCE_00983 1444711.CCJF01000005_gene1642 6.5e-106 391.0 Bacteria Bacteria COG1301@1,COG1301@2 NA|NA|NA C dicarboxylic acid transport OINAGBCE_00985 1444711.CCJF01000004_gene2265 1.1e-109 403.3 Chlamydiae tal GO:0003674,GO:0003824,GO:0004801,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 iYL1228.KPN_02798 Bacteria 2JFM5@204428,COG0176@1,COG0176@2 NA|NA|NA F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway OINAGBCE_00986 716544.wcw_0597 3.9e-21 107.5 Chlamydiae Bacteria 2E2QG@1,2JGC6@204428,32XTA@2 NA|NA|NA OINAGBCE_00987 331113.SNE_A18920 4.2e-08 66.2 Bacteria Bacteria COG3177@1,COG3177@2 NA|NA|NA D Filamentation induced by cAMP protein fic OINAGBCE_00988 1437425.CSEC_0487 9.3e-78 297.7 Chlamydiae Bacteria 2JGK9@204428,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) OINAGBCE_00991 1225184.ALXE01000019_gene4092 2.6e-08 65.9 Gammaproteobacteria Bacteria 1NJII@1224,1SIJX@1236,2D5FA@1,32TIZ@2 NA|NA|NA OINAGBCE_00996 631362.Thi970DRAFT_03186 2.4e-08 64.7 Chromatiales Bacteria 1MUMJ@1224,1RSDY@1236,1X0B5@135613,COG0399@1,COG0399@2 NA|NA|NA M Transposase zinc-binding domain OINAGBCE_01000 1267533.KB906742_gene788 5.4e-09 68.9 Bacteria Bacteria COG5563@1,COG5563@2 NA|NA|NA OINAGBCE_01001 716544.wcw_0483 8.3e-08 63.5 Chlamydiae Bacteria 2JGVA@204428,COG3328@1,COG3328@2 NA|NA|NA L Transposase and inactivated derivatives OINAGBCE_01002 716544.wcw_0483 4.3e-25 120.6 Chlamydiae Bacteria 2JGVA@204428,COG3328@1,COG3328@2 NA|NA|NA L Transposase and inactivated derivatives OINAGBCE_01003 1444711.CCJF01000005_gene1661 4.4e-23 114.8 Chlamydiae MA20_36130 Bacteria 2DMHT@1,2JHBR@204428,32RN3@2 NA|NA|NA S PEGA domain OINAGBCE_01004 96561.Dole_2567 1.2e-17 96.7 Desulfobacterales Bacteria 1NA8U@1224,2EBR1@1,2MP89@213118,2WRH5@28221,335QY@2,42W3V@68525 NA|NA|NA OINAGBCE_01005 1047013.AQSP01000142_gene217 2.8e-29 134.8 Bacteria Bacteria 2EDCN@1,3378Z@2 NA|NA|NA OINAGBCE_01006 1123376.AUIU01000003_gene1644 1.5e-77 296.2 Bacteria xre Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding OINAGBCE_01007 96561.Dole_0814 1.9e-11 74.7 Proteobacteria ko:K09144 ko00000 Bacteria 1R66E@1224,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system OINAGBCE_01009 1086011.HJ01_03340 1.1e-121 443.7 Flavobacterium Bacteria 1IAF9@117743,2NY5K@237,4NH7D@976,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family OINAGBCE_01010 375286.mma_0372 5.2e-60 237.7 Oxalobacteraceae VY92_06375 Bacteria 1R3WM@1224,2VQ6M@28216,474RB@75682,COG4380@1,COG4380@2 NA|NA|NA S Putative bacterial lipoprotein (DUF799) OINAGBCE_01011 290397.Adeh_0393 1.1e-14 86.3 Deltaproteobacteria Z012_10670 Bacteria 1PJYZ@1224,2WST6@28221,42X78@68525,COG4259@1,COG4259@2 NA|NA|NA S Domain of unknown function (DUF4810) OINAGBCE_01012 375286.mma_0370 1.6e-10 72.0 Betaproteobacteria Bacteria 1NH61@1224,2ERJU@1,2W595@28216,33J5A@2 NA|NA|NA OINAGBCE_01014 933262.AXAM01000070_gene2275 5.2e-21 107.5 Deltaproteobacteria Bacteria 1Q9X8@1224,2WWQP@28221,431MF@68525,COG1569@1,COG1569@2 NA|NA|NA S Nucleotide binding protein, PINc OINAGBCE_01015 243159.AFE_1384 2.2e-29 135.2 Acidithiobacillales Bacteria 1MZC9@1224,1S88W@1236,2ND8P@225057,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) OINAGBCE_01016 204669.Acid345_3587 1.2e-16 92.8 Bacteria Bacteria COG5606@1,COG5606@2 NA|NA|NA OINAGBCE_01018 44689.DDB0233551 4e-14 86.7 Amoebozoa GO:0000166,GO:0001882,GO:0001883,GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004672,GO:0005085,GO:0005088,GO:0005488,GO:0005515,GO:0005525,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007155,GO:0007163,GO:0007165,GO:0008150,GO:0008152,GO:0008289,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017016,GO:0017076,GO:0019001,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019932,GO:0019934,GO:0019935,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030551,GO:0030553,GO:0031267,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0032101,GO:0032268,GO:0032270,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0033674,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040012,GO:0042325,GO:0042327,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043549,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0046578,GO:0046579,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051020,GO:0051056,GO:0051057,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902531,GO:1902533 6.1.1.1 ko:K01866,ko:K03099,ko:K06262,ko:K16175 ko00970,ko01521,ko01522,ko04010,ko04012,ko04013,ko04014,ko04062,ko04068,ko04072,ko04150,ko04151,ko04320,ko04390,ko04391,ko04510,ko04512,ko04530,ko04540,ko04611,ko04630,ko04640,ko04650,ko04660,ko04662,ko04664,ko04714,ko04722,ko04810,ko04910,ko04912,ko04915,ko04917,ko04926,ko05034,ko05160,ko05165,ko05200,ko05203,ko05205,ko05206,ko05210,ko05211,ko05213,ko05214,ko05215,ko05220,ko05221,ko05223,ko05224,ko05225,ko05226,ko05231,map00970,map01521,map01522,map04010,map04012,map04013,map04014,map04062,map04068,map04072,map04150,map04151,map04320,map04390,map04391,map04510,map04512,map04530,map04540,map04611,map04630,map04640,map04650,map04660,map04662,map04664,map04714,map04722,map04810,map04910,map04912,map04915,map04917,map04926,map05034,map05160,map05165,map05200,map05203,map05205,map05206,map05210,map05211,map05213,map05214,map05215,map05220,map05221,map05223,map05224,map05225,map05226,map05231 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029,ko04090 Eukaryota 3XENG@554915,COG4886@1,KOG0619@2759,KOG3417@1,KOG3417@2759 NA|NA|NA T Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif OINAGBCE_01020 886293.Sinac_5259 1.5e-26 125.6 Planctomycetes rbpA Bacteria 2IZPY@203682,COG0724@1,COG0724@2 NA|NA|NA S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OINAGBCE_01022 765952.PUV_08850 2.7e-84 319.3 Chlamydiae murD 6.3.2.9 ko:K01925,ko:K01932 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFMY@204428,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) OINAGBCE_01023 1444711.CCJF01000005_gene1052 1.6e-139 502.7 Chlamydiae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2JFHV@204428,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan OINAGBCE_01024 1444711.CCJF01000005_gene1051 4.2e-96 358.6 Chlamydiae murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFWE@204428,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein OINAGBCE_01026 264201.pc1257 4.4e-58 231.5 Chlamydiae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2JFZ5@204428,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA OINAGBCE_01027 765952.PUV_08640 3.6e-211 741.1 Chlamydiae groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2JFHN@204428,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions OINAGBCE_01029 716544.wcw_1102 6.1e-31 140.6 Chlamydiae ko:K15977 ko00000 Bacteria 2JGCM@204428,COG2259@1,COG2259@2 NA|NA|NA S DoxX-like family OINAGBCE_01030 1444712.BN1013_01503 2.8e-35 156.0 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_01032 244581.IM40_06545 2e-137 495.7 Alphaproteobacteria yajR_1 Bacteria 1MXPM@1224,2TSB9@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily OINAGBCE_01033 1437425.CSEC_2049 4.3e-85 321.2 Chlamydiae Bacteria 2JG25@204428,COG1777@1,COG1777@2 NA|NA|NA K ROK family OINAGBCE_01034 28583.AMAG_02128T0 6.2e-21 108.2 Fungi BPL1 GO:0003674,GO:0003824,GO:0004077,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009305,GO:0009987,GO:0010467,GO:0016874,GO:0016879,GO:0018271,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:0071734,GO:0140096,GO:1901564 6.3.4.10,6.3.4.11,6.3.4.15,6.3.4.9 ko:K01942 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000 Fungi 38D3N@33154,3NXNK@4751,COG0340@1,KOG1536@2759 NA|NA|NA H Biotin apoprotein ligase OINAGBCE_01035 264201.pc0468 4.6e-131 474.6 Chlamydiae dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 ko:K03686 ko00000,ko03029,ko03110 Bacteria 2JFT3@204428,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins OINAGBCE_01036 1444711.CCJF01000004_gene2048 2.6e-17 94.0 Chlamydiae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGCV@204428,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family OINAGBCE_01037 1444712.BN1013_01649 9.7e-33 147.1 Chlamydiae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2JGBC@204428,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family OINAGBCE_01038 716544.wcw_1439 2e-112 412.5 Chlamydiae dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 2JGPH@204428,COG0232@1,COG0232@2 NA|NA|NA F Phosphohydrolase-associated domain OINAGBCE_01039 1437425.CSEC_0705 1.3e-148 533.5 Chlamydiae ptsI 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 Bacteria 2JFGB@204428,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) OINAGBCE_01040 264201.pc0475 7.7e-26 122.9 Chlamydiae ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 2JG8W@204428,COG1925@1,COG1925@2 NA|NA|NA G PTS HPr component phosphorylation site OINAGBCE_01041 264201.pc1226 2.4e-38 166.0 Chlamydiae rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 2JFRX@204428,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 OINAGBCE_01042 716544.wcw_1360 2.4e-199 701.8 Chlamydiae lysS 6.1.1.6 ko:K04567,ko:K04568 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03012,ko03016 Bacteria 2JFIC@204428,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family OINAGBCE_01043 673862.BABL1_44 2.3e-46 192.6 Deltaproteobacteria ko:K01421,ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 1QXTH@1224,2WSPR@28221,42XN1@68525,COG1682@1,COG1682@2 NA|NA|NA U Transport permease protein OINAGBCE_01045 673862.BABL1_734 1.6e-44 186.0 Deltaproteobacteria MA20_23390 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUX3@1224,2X5GZ@28221,42S93@68525,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter OINAGBCE_01047 765952.PUV_03630 4.7e-09 67.8 Chlamydiae Bacteria 2995I@1,2JHDA@204428,2ZW8V@2 NA|NA|NA OINAGBCE_01048 272624.lpg1904 2.9e-61 242.3 Legionellales Bacteria 1JCP4@118969,1NFUD@1224,1SE7Q@1236,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family OINAGBCE_01050 765914.ThisiDRAFT_0021 1.9e-82 313.2 Gammaproteobacteria ko:K07497 ko00000 Bacteria 1MWVQ@1224,1RN12@1236,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic OINAGBCE_01051 658187.LDG_7032 1.1e-140 508.8 Legionellales rarA ko:K07452,ko:K07478 ko00000,ko01000,ko02048 Bacteria 1JC4I@118969,1P522@1224,1SVJ6@1236,COG2256@1,COG2256@2 NA|NA|NA L atpase related to the helicase subunit of the holliday junction resolvase OINAGBCE_01054 765952.PUV_08220 5e-59 236.9 Chlamydiae tamB ko:K09800 ko00000,ko02000 Bacteria 2JG5X@204428,COG2911@1,COG2911@2 NA|NA|NA S TamB, inner membrane protein subunit of TAM complex OINAGBCE_01055 115711.CP_0629 5.3e-36 158.3 Chlamydiae clpB ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2JFW9@204428,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity OINAGBCE_01057 1444712.BN1013_01599 1e-76 293.9 Bacteria 2.3.1.94 ko:K10817,ko:K12443,ko:K15672 ko00522,ko01051,ko01052,ko01130,map00522,map01051,map01052,map01130 M00774 R00918 RC00004,RC02825,RC02826,RC02828,RC02829,RC02830,RC02831 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Bacteria COG0451@1,COG0451@2 NA|NA|NA GM ADP-glyceromanno-heptose 6-epimerase activity OINAGBCE_01059 1444711.CCJF01000005_gene1357 2e-78 299.7 Chlamydiae Bacteria 2JFTD@204428,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator OINAGBCE_01060 1444712.BN1013_01544 2.1e-09 69.3 Chlamydiae Bacteria 2JHHW@204428,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01061 765952.PUV_19250 9.5e-143 514.2 Chlamydiae ko:K04744 ko00000,ko02000 1.B.42.1 Bacteria 2JFGN@204428,COG1452@1,COG1452@2 NA|NA|NA M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane OINAGBCE_01063 1444712.BN1013_01106 4.9e-151 541.2 Chlamydiae ugd 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFKK@204428,COG1004@1,COG1004@2 NA|NA|NA C Belongs to the UDP-glucose GDP-mannose dehydrogenase family OINAGBCE_01064 716544.wcw_1171 8.4e-13 80.5 Chlamydiae mreD Bacteria 2CDUZ@1,2JGE4@204428,3330V@2 NA|NA|NA OINAGBCE_01065 1444711.CCJF01000005_gene1360 5.2e-84 317.8 Chlamydiae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFJ9@204428,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate OINAGBCE_01066 555779.Dthio_PD3474 5.1e-15 87.0 Desulfovibrionales ko:K21498 ko00000,ko02048 Bacteria 1N2BD@1224,2MDGH@213115,2WQN7@28221,42TY5@68525,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins OINAGBCE_01067 522306.CAP2UW1_0205 3.7e-26 124.0 Betaproteobacteria ko:K07334 ko00000,ko02048 Bacteria 1MZ4I@1224,2VUSH@28216,COG3549@1,COG3549@2 NA|NA|NA S Plasmid maintenance system killer OINAGBCE_01068 264201.pc1106 1.5e-185 656.4 Chlamydiae glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2JFKM@204428,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family OINAGBCE_01069 1444711.CCJF01000005_gene1201 1.4e-63 249.2 Chlamydiae CP_0368 Bacteria 28KCR@1,2JFPG@204428,2Z9ZJ@2 NA|NA|NA S Tir chaperone protein (CesT) family OINAGBCE_01070 331113.SNE_A08520 3.9e-33 147.9 Chlamydiae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2JG9D@204428,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein OINAGBCE_01071 264201.pc1103 3.9e-119 435.3 Chlamydiae pepA 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFEQ@204428,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides OINAGBCE_01072 1444711.CCJF01000005_gene1205 5.1e-103 381.3 Chlamydiae asd GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 ko:K00133,ko:K00134 ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010 M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552 R01061,R02291 RC00149,RC00684 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2JFDC@204428,COG0136@1,COG0136@2 NA|NA|NA E aspartate-semialdehyde dehydrogenase OINAGBCE_01074 1485545.JQLW01000005_gene1059 1.6e-31 142.5 Proteobacteria Bacteria 1N1W1@1224,COG4914@1,COG4914@2 NA|NA|NA OINAGBCE_01077 1444711.CCJF01000001_gene110 5.6e-136 490.7 Chlamydiae Bacteria 2JG7E@204428,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family OINAGBCE_01078 1444711.CCJF01000001_gene109 9.6e-150 536.6 Chlamydiae Bacteria 2JG0J@204428,COG4804@1,COG4804@2 NA|NA|NA S Protein of unknown function (DUF1016) OINAGBCE_01080 1444712.BN1013_02419 1e-45 189.9 Chlamydiae 2.3.1.59 ko:K17840 br01600,ko00000,ko01000,ko01504 Bacteria 2JH30@204428,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain OINAGBCE_01081 1437425.CSEC_1415 6.1e-143 513.8 Bacteria Bacteria COG1619@1,COG1619@2 NA|NA|NA V carboxypeptidase activity OINAGBCE_01082 1444712.BN1013_00100 2.2e-54 218.4 Chlamydiae Bacteria 2JH41@204428,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain OINAGBCE_01083 1437425.CSEC_2043 7.2e-38 163.7 Bacteria yhfO ko:K03825 ko00000,ko01000 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase OINAGBCE_01084 1444711.CCJF01000004_gene2136 3.1e-106 391.7 Chlamydiae Bacteria 2JG0B@204428,COG2334@1,COG2334@2 NA|NA|NA S Phosphotransferase enzyme family OINAGBCE_01085 244582.JQAK01000002_gene464 2e-92 345.9 Rickettsiales yqkA 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1RH46@1224,2U2UV@28211,47GT1@766,COG0454@1,COG0456@2,COG2320@1,COG2320@2 NA|NA|NA K GrpB protein OINAGBCE_01090 264201.pc0519 1.2e-93 349.4 Chlamydiae vatD ko:K18234 ko00000,ko01000,ko01504 Bacteria 2JGJT@204428,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) OINAGBCE_01092 1444712.BN1013_00926 1.3e-39 169.5 Bacteria ndk 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate OINAGBCE_01095 1306947.ARQD01000003_gene247 1.1e-53 216.1 unclassified Bacteria hbpS ko:K11477 ko00000 Bacteria 2NRT9@2323,COG3193@1,COG3193@2 NA|NA|NA S Haem-degrading OINAGBCE_01096 765952.PUV_13170 4e-96 357.8 Chlamydiae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 2JFHY@204428,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) OINAGBCE_01097 264201.pc1173 2.6e-63 248.8 Chlamydiae ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2JGVZ@204428,COG0327@1,COG0327@2 NA|NA|NA S NIF3 (NGG1p interacting factor 3) OINAGBCE_01098 765952.PUV_13140 8.9e-53 213.8 Chlamydiae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 2JG19@204428,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate OINAGBCE_01099 1444712.BN1013_01470 4.2e-47 194.1 Chlamydiae yqdE ko:K08999 ko00000 Bacteria 2JG2Y@204428,COG1259@1,COG1259@2 NA|NA|NA S Bifunctional nuclease OINAGBCE_01100 562970.Btus_3191 8.9e-16 89.4 Bacteria Bacteria COG2161@1,COG2161@2 NA|NA|NA D toxin-antitoxin pair type II binding OINAGBCE_01101 331678.Cphamn1_2339 1e-29 136.3 Bacteria vapC 2.3.1.30 ko:K00640,ko:K07062 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity OINAGBCE_01102 4533.OB06G21890.1 4.3e-08 66.6 Poales GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005777,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0009719,GO:0009725,GO:0009737,GO:0009909,GO:0009987,GO:0010033,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0033993,GO:0035091,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048580,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051239,GO:0065007,GO:0097305,GO:1901700,GO:1902074,GO:2000026,GO:2000241 ko:K08770 ko03320,map03320 ko00000,ko00001,ko04121 Viridiplantae 37RMX@33090,3G9F1@35493,3IFGR@38820,3KYYV@4447,COG5272@1,KOG0001@2759,KOG2381@1,KOG2381@2759 NA|NA|NA G Phosphatidylinositol 3- and 4-kinase OINAGBCE_01104 1444711.CCJF01000004_gene2029 1.1e-209 736.1 Chlamydiae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 2JFJQ@204428,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein OINAGBCE_01105 765952.PUV_13740 5.6e-69 267.3 Chlamydiae lemA ko:K03744 ko00000 Bacteria 2JFZQ@204428,COG1704@1,COG1704@2 NA|NA|NA S LemA family OINAGBCE_01108 264201.pc0874 1.7e-97 362.8 Chlamydiae potD ko:K11069,ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 2JGD6@204428,COG0687@1,COG0687@2 NA|NA|NA E Bacterial extracellular solute-binding protein OINAGBCE_01109 765952.PUV_07590 3.8e-86 324.7 Chlamydiae potC ko:K11069,ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iHN637.CLJU_RS10670 Bacteria 2JFN9@204428,COG1177@1,COG1177@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component OINAGBCE_01110 765952.PUV_07600 2.9e-90 338.6 Chlamydiae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 2JG99@204428,COG1176@1,COG1176@2 NA|NA|NA P ABC-type spermidine putrescine transport system, permease component I OINAGBCE_01111 1444711.CCJF01000005_gene1483 2.2e-152 545.4 Chlamydiae potA 3.6.3.31 ko:K11072 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 Bacteria 2JFST@204428,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system OINAGBCE_01112 112098.XP_008617646.1 2e-21 109.8 Eukaryota GO:0002791,GO:0002792,GO:0003674,GO:0003824,GO:0004439,GO:0004721,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006464,GO:0006470,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010646,GO:0010648,GO:0010817,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0019637,GO:0019866,GO:0023051,GO:0023057,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031975,GO:0032048,GO:0032049,GO:0032592,GO:0032879,GO:0032880,GO:0034593,GO:0034595,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046676,GO:0046883,GO:0046888,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050708,GO:0050709,GO:0050789,GO:0050794,GO:0050796,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0052866,GO:0060341,GO:0061178,GO:0061179,GO:0065007,GO:0065008,GO:0070201,GO:0071704,GO:0090087,GO:0090276,GO:0090278,GO:0090407,GO:0098573,GO:0106019,GO:0140096,GO:1901564,GO:1901576,GO:1903530,GO:1903531,GO:1904950 3.1.3.16,3.1.3.48 ko:K07297,ko:K14165,ko:K20407 ko04150,ko04152,ko04211,ko04920,ko04932,map04150,map04152,map04211,map04920,map04932 ko00000,ko00001,ko01000,ko01009 Eukaryota KOG1719@1,KOG1719@2759 NA|NA|NA S phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity OINAGBCE_01113 227086.JGI_V11_140250 8.5e-10 71.2 Eukaryota Eukaryota 2DA4V@1,2S5F4@2759 NA|NA|NA OINAGBCE_01114 1207063.P24_02571 4.2e-50 205.7 Rhodospirillales ampG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria 1MUZ8@1224,2JYWZ@204441,2TTD2@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Acetyl-coenzyme A transporter 1 OINAGBCE_01115 264201.pc0581 4.8e-272 943.7 Chlamydiae CP_0264 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2JFEZ@204428,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family OINAGBCE_01116 765952.PUV_20710 5.8e-118 430.6 Chlamydiae CP_0265 Bacteria 2JFGF@204428,COG4286@1,COG4286@2 NA|NA|NA S conserved protein related to MYG1 family OINAGBCE_01117 765952.PUV_20700 2.3e-35 154.8 Chlamydiae hinT ko:K02503 ko00000,ko04147 Bacteria 2JG6G@204428,COG0537@1,COG0537@2 NA|NA|NA FG catalytic activity OINAGBCE_01118 716544.wcw_0574 1.6e-35 156.0 Chlamydiae pncA Bacteria 2JG22@204428,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family OINAGBCE_01119 716544.wcw_0575 1.4e-61 244.2 Chlamydiae CP_0267 Bacteria 2JFPT@204428,COG1413@1,COG1413@2 NA|NA|NA C lyase activity OINAGBCE_01120 765952.PUV_20580 1.6e-39 170.2 Chlamydiae yzeB ko:K02050,ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2JGY2@204428,COG0600@1,COG0600@2,COG0715@1,COG0715@2 NA|NA|NA P ABC transporter, permease protein OINAGBCE_01121 1437425.CSEC_1170 6e-94 351.3 Chlamydiae 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2JFCK@204428,COG0006@1,COG0006@2 NA|NA|NA E Metallopeptidase family M24 OINAGBCE_01122 1444711.CCJF01000004_gene2223 3.4e-97 362.1 Chlamydiae tyrP_3 ko:K03834 ko00000,ko02000 2.A.42.1.1 Bacteria 2JFIB@204428,COG0814@1,COG0814@2 NA|NA|NA E Tryptophan/tyrosine permease family OINAGBCE_01123 765952.PUV_23630 2.1e-12 78.2 Chlamydiae ko:K02116 ko00000,ko00194 3.A.2.1 Bacteria 2EQQP@1,2JGJU@204428,33IAK@2 NA|NA|NA S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter OINAGBCE_01124 1444711.CCJF01000004_gene2293 9.5e-72 276.9 Chlamydiae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2JFFC@204428,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane OINAGBCE_01125 1437425.CSEC_0649 3.1e-23 114.0 Chlamydiae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2JGFR@204428,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation OINAGBCE_01126 1444711.CCJF01000004_gene2295 1.9e-27 129.0 Chlamydiae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2JGAI@204428,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) OINAGBCE_01127 1292035.H476_3171 5.9e-20 104.4 Peptostreptococcaceae atpH ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,24MSA@186801,25RIK@186804,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation OINAGBCE_01128 1444711.CCJF01000004_gene2297 6.9e-212 743.4 Chlamydiae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2JFVK@204428,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit OINAGBCE_01129 1444711.CCJF01000004_gene2298 1e-71 276.9 Chlamydiae atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2JG12@204428,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex OINAGBCE_01130 1444711.CCJF01000004_gene2299 4.4e-213 747.3 Chlamydiae atpD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2JFHQ@204428,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits OINAGBCE_01131 765952.PUV_23540 1.9e-14 85.1 Bacteria atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria COG0355@1,COG0355@2 NA|NA|NA C proton-transporting ATP synthase activity, rotational mechanism OINAGBCE_01133 5911.EAS04482 1.2e-10 75.1 Ciliophora 2.7.11.1 ko:K13412 ko04626,ko05145,map04626,map05145 ko00000,ko00001,ko01000,ko01001 Eukaryota 3ZCZP@5878,KOG0032@1,KOG0032@2759 NA|NA|NA T Lipopolysaccharide kinase (Kdo/WaaP) family OINAGBCE_01134 1444711.CCJF01000004_gene2227 4.8e-41 174.1 Chlamydiae sufE ko:K02426,ko:K07125 ko00000 Bacteria 2JG8A@204428,COG2166@1,COG2166@2 NA|NA|NA S Fe-S metabolism associated domain OINAGBCE_01135 716544.wcw_0538 3.1e-57 228.4 Chlamydiae pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 2JFY1@204428,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family OINAGBCE_01136 1444711.CCJF01000004_gene2098 4.5e-176 624.4 Chlamydiae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 2JFTN@204428,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP OINAGBCE_01137 1123508.JH636444_gene5663 2.3e-115 422.5 Planctomycetes nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2IY36@203682,COG3004@1,COG3004@2 NA|NA|NA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons OINAGBCE_01138 331113.SNE_A22960 7.3e-54 218.4 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01140 716544.wcw_0730 4.1e-14 85.5 Chlamydiae sscA ko:K15368 ko00000 Bacteria 2JHHW@204428,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01143 1343739.PAP_06375 1.3e-10 73.2 Thermococci GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.1.3.48 ko:K14165 ko00000,ko01000,ko01009 Archaea 244D0@183968,2Y1DR@28890,COG2453@1,arCOG03413@2157 NA|NA|NA T Dual specificity phosphatase, catalytic domain OINAGBCE_01144 765952.PUV_12190 2.3e-20 109.0 Bacteria 2.7.9.1,2.7.9.2 ko:K01006,ko:K01007 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria COG0574@1,COG0574@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family OINAGBCE_01146 1408304.JAHA01000003_gene3124 6e-16 90.9 Butyrivibrio aroK 1.1.1.25,2.7.1.71,4.2.3.4 ko:K00014,ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R02413,R03083 RC00002,RC00078,RC00206,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQRY@1239,2497S@186801,4BXDP@830,COG0169@1,COG0169@2,COG0703@1,COG0703@2 NA|NA|NA E Shikimate dehydrogenase substrate binding domain OINAGBCE_01147 765952.PUV_21140 7.7e-83 314.3 Chlamydiae aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2JG7W@204428,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate OINAGBCE_01148 765952.PUV_11440 3.2e-30 139.0 Chlamydiae Bacteria 29JZV@1,2JG2R@204428,306X4@2 NA|NA|NA OINAGBCE_01149 1437425.CSEC_0561 7e-126 458.0 Chlamydiae lepB 3.4.21.89 ko:K03100,ko:K13280 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFVN@204428,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family OINAGBCE_01151 331113.SNE_A15960 1e-52 214.2 Chlamydiae Bacteria 28N6X@1,2JFR2@204428,2ZBBQ@2 NA|NA|NA S Major Facilitator Superfamily OINAGBCE_01152 926561.KB900620_gene3181 1.2e-38 166.8 Halanaerobiales adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,247YN@186801,3WAJC@53433,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism OINAGBCE_01153 765952.PUV_12720 0.0 1426.0 Chlamydiae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFQJ@204428,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) OINAGBCE_01155 2074.JNYD01000008_gene1181 3.4e-28 131.3 Pseudonocardiales Bacteria 2H654@201174,4EBUP@85010,COG2445@1,COG2445@2 NA|NA|NA S Protein of unknown function DUF86 OINAGBCE_01156 2074.JNYD01000008_gene1182 1.7e-18 99.4 Pseudonocardiales Bacteria 2H99K@201174,4EC8M@85010,COG1669@1,COG1669@2 NA|NA|NA S nucleotidyltransferase activity OINAGBCE_01158 1123368.AUIS01000007_gene2818 1.8e-30 139.0 Gammaproteobacteria ko:K09122 ko00000 Bacteria 1R442@1224,1S4UH@1236,COG1656@1,COG1656@2 NA|NA|NA H Mut7-C RNAse domain OINAGBCE_01159 396588.Tgr7_2091 1.2e-23 115.9 Gammaproteobacteria Bacteria 1NAN6@1224,1SCBD@1236,COG4634@1,COG4634@2 NA|NA|NA OINAGBCE_01160 56110.Oscil6304_3646 2e-22 111.3 Oscillatoriales Bacteria 1G7V4@1117,1HCE8@1150,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) OINAGBCE_01162 82654.Pse7367_1269 7e-21 107.1 Oscillatoriales wecD GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.210 ko:K16704 ko00000,ko01000 Bacteria 1GQ65@1117,1HBUW@1150,COG0454@1,COG0454@2 NA|NA|NA K Gcn5-related n-acetyltransferase OINAGBCE_01163 765952.PUV_07090 8.5e-38 164.5 Chlamydiae Bacteria 292D5@1,2JHBV@204428,2ZPXG@2 NA|NA|NA OINAGBCE_01165 1444711.CCJF01000004_gene2071 5.6e-170 604.0 Chlamydiae phoH ko:K07175 ko00000 Bacteria 2JFG7@204428,COG1875@1,COG1875@2 NA|NA|NA T phosphate starvation-inducible protein PhoH OINAGBCE_01166 765952.PUV_17080 2.4e-50 205.7 Chlamydiae Bacteria 292EW@1,2JG20@204428,2ZPZ5@2 NA|NA|NA OINAGBCE_01167 1444712.BN1013_00600 1.3e-77 297.0 Chlamydiae CP_0670 Bacteria 2CD1E@1,2JFU1@204428,2ZB0F@2 NA|NA|NA S Bacterial SH3 domain homologues OINAGBCE_01168 264201.pc0480 6.5e-154 550.8 Chlamydiae comM ko:K07391 ko00000 Bacteria 2JGPP@204428,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI C-terminal OINAGBCE_01169 716544.wcw_1541 9.5e-50 204.1 Chlamydiae Bacteria 2JG13@204428,COG2849@1,COG2849@2 NA|NA|NA S repeat protein OINAGBCE_01170 1444711.CCJF01000005_gene852 1.6e-170 606.7 Chlamydiae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 2JFCR@204428,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily OINAGBCE_01171 395493.BegalDRAFT_3458 5.9e-50 203.8 Thiotrichales ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1R9ZA@1224,1S1Z3@1236,460K8@72273,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate OINAGBCE_01173 1444712.BN1013_02348 1.8e-32 146.0 Bacteria 3.1.1.53,3.2.1.4 ko:K01179,ko:K05970 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria COG4886@1,COG4886@2 NA|NA|NA S regulation of response to stimulus OINAGBCE_01174 247490.KSU1_C0527 2.7e-153 548.5 Planctomycetes copA 1.16.3.3 ko:K22348 ko00000,ko01000 Bacteria 2IX3N@203682,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase OINAGBCE_01175 1444712.BN1013_02346 5.2e-102 378.3 Chlamydiae copB ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 2JGB1@204428,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein OINAGBCE_01177 1215114.BBIU01000039_gene3845 7.7e-09 68.9 Gammaproteobacteria Bacteria 1N4JY@1224,1S9T0@1236,COG4886@1,COG4886@2 NA|NA|NA S SMART leucine-rich repeat-containing protein typical subtype OINAGBCE_01179 312284.A20C1_04101 1.2e-41 178.3 unclassified Actinobacteria (class) Bacteria 2IG31@201174,3UXAU@52018,COG5184@1,COG5184@2 NA|NA|NA DOZ Evidence 5 No homology to any previously reported sequences OINAGBCE_01180 716544.wcw_0739 6.3e-20 103.6 Chlamydiae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 2JGEI@204428,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) OINAGBCE_01181 1444712.BN1013_01554 6.6e-180 637.1 Chlamydiae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2JFF1@204428,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) OINAGBCE_01182 264201.pc0669 1.3e-191 676.0 Chlamydiae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2JFE7@204428,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) OINAGBCE_01184 1437425.CSEC_1771 7.1e-33 148.3 Chlamydiae licD ko:K07271 ko00000,ko01000 Bacteria 2JHA6@204428,COG3475@1,COG3475@2 NA|NA|NA M LicD family OINAGBCE_01185 227377.CBUA0027 7.4e-33 146.4 Legionellales ko:K07726 ko00000,ko03000 Bacteria 1JENB@118969,1N05Y@1224,1SCCM@1236,COG2944@1,COG2944@2 NA|NA|NA K Transcriptional regulator OINAGBCE_01187 385682.AFSL01000088_gene852 5.7e-100 371.3 Bacteroidia Bacteria 2FRWC@200643,4NJ8G@976,COG3547@1,COG3547@2 NA|NA|NA L COG COG3547 Transposase and inactivated derivatives OINAGBCE_01188 742727.HMPREF9447_01328 3.4e-26 124.8 Bacteroidaceae Bacteria 2C4SU@1,2FVN6@200643,33I95@2,4ASUR@815,4PCQ3@976 NA|NA|NA S Domain of unknown function (DUF4304) OINAGBCE_01189 765952.PUV_20630 4.4e-165 589.7 Chlamydiae Bacteria 2JFH5@204428,COG3209@1,COG3209@2 NA|NA|NA M Rhs family OINAGBCE_01194 316067.Geob_1040 1.1e-42 180.6 delta/epsilon subdivisions dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1MX0E@1224,42RDM@68525,COG0593@1,COG0593@2,COG1943@1,COG1943@2 NA|NA|NA L Chromosomal replication initiator, DnaA OINAGBCE_01197 86106.I862_07370 1.1e-26 125.9 Rickettsiales GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K07171 ko00000,ko01000,ko02048 Bacteria 1N0JV@1224,2UFG0@28211,47GG9@766,COG2337@1,COG2337@2 NA|NA|NA L PemK-like, MazF-like toxin of type II toxin-antitoxin system OINAGBCE_01198 373994.Riv7116_3727 1.2e-22 113.2 Cyanobacteria Bacteria 1G6I4@1117,COG2340@1,COG2340@2 NA|NA|NA S protein with SCP PR1 domains OINAGBCE_01199 1444712.BN1013_00959 1.3e-75 290.4 Chlamydiae dacC 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2JFGM@204428,COG1686@1,COG1686@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase OINAGBCE_01200 55529.EKX47640 1.4e-08 67.8 Eukaryota 2.7.11.1 ko:K17535 ko00000,ko01000,ko01001 Eukaryota COG0515@1,KOG0192@2759 NA|NA|NA KLT protein kinase activity OINAGBCE_01201 521674.Plim_0263 1.7e-274 952.2 Planctomycetes ctpF GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.8 ko:K01537,ko:K12953 ko00000,ko01000 3.A.3,3.A.3.2 Bacteria 2IXV7@203682,COG0474@1,COG0474@2 NA|NA|NA P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC OINAGBCE_01204 1303518.CCALI_01075 1.7e-20 106.3 Bacteria def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.1.2.9,3.5.1.88 ko:K00604,ko:K01462 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria COG0242@1,COG0242@2 NA|NA|NA J peptide deformylase activity OINAGBCE_01205 926569.ANT_29010 7.1e-41 174.5 Chloroflexi hflC Bacteria 2G5SB@200795,COG0330@1,COG0330@2 NA|NA|NA O PFAM band 7 protein OINAGBCE_01206 765952.PUV_26750 8.8e-112 410.6 Chlamydiae gltT ko:K03309 ko00000 2.A.23 Bacteria 2JFGX@204428,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family OINAGBCE_01207 1437425.CSEC_1327 2.6e-80 306.2 Chlamydiae norM-2 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2JFXX@204428,COG0534@1,COG0534@2 NA|NA|NA V MatE OINAGBCE_01209 1444712.BN1013_00765 2.5e-16 90.9 Chlamydiae CP_0775 ko:K09779 ko00000 Bacteria 2JGIY@204428,COG2155@1,COG2155@2 NA|NA|NA S Domain of unknown function (DUF378) OINAGBCE_01210 716544.wcw_1634 1.4e-175 623.2 Chlamydiae cadA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.3,3.6.3.5 ko:K01534,ko:K12951,ko:K21887 ko00000,ko01000 3.A.3,3.A.3.6 Bacteria 2JFGU@204428,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase OINAGBCE_01211 1444712.BN1013_01356 1e-60 240.4 Chlamydiae CP_1000 Bacteria 2JFYP@204428,COG1814@1,COG1814@2 NA|NA|NA S VIT family OINAGBCE_01214 1487953.JMKF01000086_gene5563 2.8e-71 275.8 Oscillatoriales selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K06917 ko00000,ko01000,ko03016 Bacteria 1G2AY@1117,1H91A@1150,COG2603@1,COG2603@2 NA|NA|NA S Trna 2-selenouridine synthase OINAGBCE_01215 1444711.CCJF01000005_gene750 7.1e-162 577.0 Chlamydiae serS 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFDJ@204428,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) OINAGBCE_01216 765952.PUV_07220 1.7e-28 134.0 Chlamydiae ipdC 4.1.1.74 ko:K04103 ko00380,ko01100,map00380,map01100 R01974 RC00506 ko00000,ko00001,ko01000 Bacteria 2JFKC@204428,COG3961@1,COG3961@2 NA|NA|NA GH Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase OINAGBCE_01217 264201.pc0261 3e-196 691.8 Chlamydiae rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFMQ@204428,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease OINAGBCE_01218 765952.PUV_02100 1e-59 237.3 Chlamydiae ytgD ko:K11709 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 2JFM1@204428,COG1108@1,COG1108@2 NA|NA|NA P transport system membrane protein OINAGBCE_01219 1444711.CCJF01000005_gene717 6.3e-100 371.3 Chlamydiae ytgC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09819,ko:K11708 ko02010,map02010 M00243,M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 2JFJ5@204428,COG1108@1,COG1108@2,COG1321@1,COG1321@2 NA|NA|NA P transport system membrane protein OINAGBCE_01220 264201.pc0257 1.1e-77 296.6 Chlamydiae mntB ko:K09817,ko:K11710 ko02010,map02010 M00242,M00319 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 iYO844.BSU30760 Bacteria 2JFS6@204428,COG1121@1,COG1121@2 NA|NA|NA P Part of an ATP-driven transport system CPn0346 CPn0347 CPn0348 CPn0349 for a metal. Probably responsible for energy coupling to the transport system OINAGBCE_01221 1437425.CSEC_1937 4.4e-90 338.2 Chlamydiae troA GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K11707 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 2JFSX@204428,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family OINAGBCE_01222 264201.pc0253 5.9e-48 197.2 Chlamydiae CP_0409 Bacteria 2CDV0@1,2JG2K@204428,3071V@2 NA|NA|NA OINAGBCE_01223 765952.PUV_01590 3.6e-53 214.5 Chlamydiae ispF GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 2JG09@204428,COG0245@1,COG0245@2 NA|NA|NA I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) OINAGBCE_01224 264201.pc0226 8.4e-81 307.4 Chlamydiae cysJ GO:0000166,GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016667,GO:0016668,GO:0032553,GO:0032991,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 iECO26_1355.ECO26_3835,iECSE_1348.ECSE_3020,iECW_1372.ECW_m2972,iEKO11_1354.EKO11_1004,iEcE24377_1341.EcE24377A_3066,iEcolC_1368.EcolC_0948,iWFL_1372.ECW_m2972,iYO844.BSU33440 Bacteria 2JFKP@204428,COG0369@1,COG0369@2 NA|NA|NA P sulfite reductase OINAGBCE_01225 1444712.BN1013_00519 2e-219 768.5 Chlamydiae gltX 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2JFU2@204428,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) OINAGBCE_01226 1444712.BN1013_00520 3.7e-11 74.3 Chlamydiae prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 2JFNQ@204428,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family OINAGBCE_01227 1122165.AUHS01000030_gene2295 5.4e-37 160.6 Legionellales ko:K03828 ko00000,ko01000 Bacteria 1JF9I@118969,1PEXG@1224,1SXGQ@1236,COG0454@1,COG0456@2,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein OINAGBCE_01228 1304880.JAGB01000002_gene1851 9.6e-33 146.4 Clostridia Bacteria 1V6R7@1239,25DJJ@186801,COG1669@1,COG1669@2 NA|NA|NA S nucleotidyltransferase substrate binding protein, HI0074 family OINAGBCE_01229 1443125.Z962_06470 3.6e-19 100.9 Clostridiaceae Bacteria 1VGI3@1239,25DNG@186801,36MR5@31979,COG1708@1,COG1708@2 NA|NA|NA S Nucleotidyltransferase domain OINAGBCE_01230 716544.wcw_p0021 8.3e-19 99.4 Bacteria Bacteria 2EH4M@1,33AWJ@2 NA|NA|NA OINAGBCE_01231 716544.wcw_1207 3e-33 147.9 Chlamydiae ko:K07171 ko00000,ko01000,ko02048 Bacteria 2JHEQ@204428,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module OINAGBCE_01232 1444711.CCJF01000005_gene1795 3.2e-46 191.8 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity OINAGBCE_01236 1200557.JHWV01000019_gene1211 3.7e-68 265.0 Negativicutes metQ ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,4H2GM@909932,COG1464@1,COG1464@2 NA|NA|NA M Belongs to the nlpA lipoprotein family OINAGBCE_01237 1444711.CCJF01000004_gene2034 1.8e-71 275.8 Chlamydiae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2JGUP@204428,COG2011@1,COG2011@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component OINAGBCE_01238 1262914.BN533_00589 2.9e-92 345.5 Negativicutes metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,4H23H@909932,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system OINAGBCE_01239 765952.PUV_03410 7.6e-71 273.5 Chlamydiae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2JG0U@204428,COG2818@1,COG2818@2 NA|NA|NA L Methyladenine glycosylase OINAGBCE_01241 1288494.EBAPG3_22520 2.8e-69 269.2 Nitrosomonadales ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1MW61@1224,2VHRC@28216,3726I@32003,COG0282@1,COG0282@2 NA|NA|NA H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction OINAGBCE_01242 765952.PUV_22030 0.0 1278.8 Chlamydiae xfp GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 2JFQV@204428,COG3957@1,COG3957@2 NA|NA|NA G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase OINAGBCE_01243 1131553.JIBI01000042_gene1997 1.3e-136 493.0 Nitrosomonadales srmB GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008104,GO:0008143,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0033036,GO:0033592,GO:0034622,GO:0034641,GO:0035770,GO:0036464,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0046483,GO:0051179,GO:0060293,GO:0065003,GO:0070035,GO:0070717,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901363,GO:1990904 3.6.4.13 ko:K05590,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1MU49@1224,2VH16@28216,371SP@32003,COG0513@1,COG0513@2 NA|NA|NA JKL Belongs to the DEAD box helicase family OINAGBCE_01244 716544.wcw_1511 8.6e-91 341.3 Chlamydiae lnt ko:K03820 ko00000,ko01000 GT2 Bacteria 2JFX7@204428,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins OINAGBCE_01245 716544.wcw_1515 6.9e-116 424.1 Chlamydiae rsmB 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 2JFP8@204428,COG0144@1,COG0144@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family OINAGBCE_01246 765952.PUV_22230 3.3e-64 252.3 Chlamydiae 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2JG1Y@204428,COG0760@1,COG0760@2 NA|NA|NA O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation OINAGBCE_01247 1444711.CCJF01000004_gene1966 6.4e-57 227.6 Chlamydiae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 2JFY7@204428,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits OINAGBCE_01250 765952.PUV_20630 3.6e-63 249.6 Chlamydiae Bacteria 2JFH5@204428,COG3209@1,COG3209@2 NA|NA|NA M Rhs family OINAGBCE_01254 1444711.CCJF01000005_gene1714 3e-88 331.6 Chlamydiae ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 6.3.4.19 ko:K04075,ko:K14058 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 2JFSJ@204428,COG0037@1,COG0037@2 NA|NA|NA H Belongs to the TtcA family OINAGBCE_01255 765952.PUV_14110 4.8e-122 444.1 Chlamydiae Bacteria 2JFQ2@204428,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) OINAGBCE_01257 1444712.BN1013_00774 1.8e-34 152.1 Bacteria Bacteria COG5606@1,COG5606@2 NA|NA|NA OINAGBCE_01258 1444712.BN1013_00775 3.7e-37 161.0 Bacteria Bacteria COG4679@1,COG4679@2 NA|NA|NA K PFAM Phage derived protein Gp49-like (DUF891) OINAGBCE_01260 1306174.JODP01000001_gene4982 1.4e-27 131.3 Actinobacteria 2.7.11.1,3.2.1.4 ko:K01179,ko:K12567,ko:K13277,ko:K20276 ko00500,ko01100,ko02024,ko05410,ko05414,map00500,map01100,map02024,map05410,map05414 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01001,ko01002,ko03110,ko04131,ko04147,ko04812 GH5,GH9 Bacteria 2HCJX@201174,COG3468@1,COG3468@2,COG4257@1,COG4257@2,COG4733@1,COG4733@2,COG4870@1,COG4870@2 NA|NA|NA MU ig-like, plexins, transcription factors OINAGBCE_01265 1444711.CCJF01000005_gene1301 5.2e-94 350.9 Chlamydiae mlaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2JFCS@204428,COG0767@1,COG0767@2 NA|NA|NA Q Permease MlaE OINAGBCE_01266 1444711.CCJF01000005_gene1300 3.3e-72 278.5 Chlamydiae mkl ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2JFQY@204428,COG1127@1,COG1127@2 NA|NA|NA Q ABC transporter OINAGBCE_01267 1444712.BN1013_01052 8e-51 207.6 Chlamydiae ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2JFN3@204428,COG1463@1,COG1463@2 NA|NA|NA Q MlaD protein OINAGBCE_01268 1444711.CCJF01000005_gene1298 4.7e-81 307.4 Chlamydiae yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07735 ko00000,ko03000 Bacteria 2JFR0@204428,COG1678@1,COG1678@2 NA|NA|NA K Belongs to the UPF0301 (AlgH) family OINAGBCE_01269 1444711.CCJF01000005_gene1296 1e-39 169.5 Chlamydiae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG8N@204428,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family OINAGBCE_01270 264201.pc1757 8e-44 183.3 Chlamydiae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGX6@204428,COG0102@1,COG0102@2 NA|NA|NA J Ribosomal protein L13 OINAGBCE_01271 1444711.CCJF01000005_gene1294 2.8e-185 654.8 Chlamydiae miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2JFWW@204428,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine OINAGBCE_01272 765952.PUV_04180 5.7e-23 115.9 Chlamydiae Bacteria 2JHAB@204428,COG3328@1,COG3328@2 NA|NA|NA L transposase activity OINAGBCE_01276 398767.Glov_3037 6.2e-44 184.9 Deltaproteobacteria dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1MX0E@1224,2WM14@28221,42NN0@68525,COG0593@1,COG0593@2,COG1943@1,COG1943@2 NA|NA|NA L SMART Chromosomal replication initiator DnaA domain OINAGBCE_01278 716544.wcw_0730 1.2e-18 100.5 Chlamydiae sscA ko:K15368 ko00000 Bacteria 2JHHW@204428,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01279 691883.XP_009495012.1 8.2e-11 76.3 Opisthokonta ko:K03099 ko01521,ko01522,ko04010,ko04012,ko04013,ko04014,ko04062,ko04068,ko04072,ko04150,ko04151,ko04320,ko04510,ko04540,ko04630,ko04650,ko04660,ko04662,ko04664,ko04714,ko04722,ko04810,ko04910,ko04912,ko04915,ko04917,ko04926,ko05034,ko05160,ko05165,ko05200,ko05205,ko05206,ko05210,ko05211,ko05213,ko05214,ko05215,ko05220,ko05221,ko05223,ko05224,ko05225,ko05226,ko05231,map01521,map01522,map04010,map04012,map04013,map04014,map04062,map04068,map04072,map04150,map04151,map04320,map04510,map04540,map04630,map04650,map04660,map04662,map04664,map04714,map04722,map04810,map04910,map04912,map04915,map04917,map04926,map05034,map05160,map05165,map05200,map05205,map05206,map05210,map05211,map05213,map05214,map05215,map05220,map05221,map05223,map05224,map05225,map05226,map05231 ko00000,ko00001 Opisthokonta 39PD7@33154,KOG3417@1,KOG3417@2759 NA|NA|NA T Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif OINAGBCE_01285 135651.CBN11731 3.6e-08 66.2 Rhabditida bath-40 GO:0003674,GO:0005488,GO:0005515 Nematoda 1KU3Q@119089,39XN4@33154,3BP07@33208,3D5GW@33213,40BBG@6231,40U7Y@6236,KOG1987@1,KOG1987@2759 NA|NA|NA D Broad-Complex, Tramtrack and Bric a brac OINAGBCE_01286 1444711.CCJF01000003_gene17 8.3e-191 673.3 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01289 765952.PUV_09480 2.4e-07 60.8 Chlamydiae Bacteria 2JGVA@204428,COG3328@1,COG3328@2 NA|NA|NA L Transposase and inactivated derivatives OINAGBCE_01290 1123401.JHYQ01000014_gene803 1.7e-126 459.5 Thiotrichales ko:K06921 ko00000 Bacteria 1MWJX@1224,1RWRA@1236,461SW@72273,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function OINAGBCE_01292 1532558.JL39_17630 9.3e-43 180.6 Rhizobiaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXM5@1224,2TUAG@28211,4BBDG@82115,COG0329@1,COG0329@2 NA|NA|NA EM Belongs to the DapA family OINAGBCE_01293 755732.Fluta_2624 2.8e-36 158.3 Flavobacteriia ydcG Bacteria 1I3EG@117743,4NRT8@976,COG1673@1,COG1673@2 NA|NA|NA S Belongs to the UPF0310 family OINAGBCE_01294 244582.JQAK01000002_gene518 5.6e-51 207.2 Rickettsiales ydcH GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 Bacteria 1N7Z7@1224,2UGIE@28211,47GAI@766,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein OINAGBCE_01295 244582.JQAK01000002_gene517 1.2e-30 139.0 Rickettsiales Bacteria 1RIRW@1224,2UM8F@28211,47GF7@766,COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity OINAGBCE_01297 331113.SNE_A22960 1.9e-126 459.5 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01299 1444711.CCJF01000005_gene1113 1.4e-161 576.6 Chlamydiae pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 2JFQ1@204428,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F OINAGBCE_01301 1121405.dsmv_3345 5.9e-20 103.2 Deltaproteobacteria Bacteria 1N9U3@1224,2WWJS@28221,4320A@68525,COG5304@1,COG5304@2 NA|NA|NA OINAGBCE_01302 945713.IALB_2782 2.8e-26 124.4 Bacteria ko:K09803 ko00000 Bacteria COG2929@1,COG2929@2 NA|NA|NA S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system OINAGBCE_01303 1437425.CSEC_0832 4e-21 108.2 Chlamydiae 3.6.1.67 ko:K19965 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2JHG1@204428,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain OINAGBCE_01304 264201.pc1859 3.3e-37 161.8 Chlamydiae rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2JG83@204428,COG0742@1,COG0742@2 NA|NA|NA L RNA cap guanine-N2 methyltransferase OINAGBCE_01305 765952.PUV_27320 2.7e-40 172.9 Chlamydiae Bacteria 2JFXG@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01306 1444711.CCJF01000005_gene229 2.4e-98 365.5 Chlamydiae Bacteria 2JFTJ@204428,COG0697@1,COG0697@2 NA|NA|NA EG Permeases of the drug metabolite transporter (DMT) superfamily OINAGBCE_01307 765952.PUV_00790 3.8e-92 344.7 Chlamydiae Bacteria 2JFNH@204428,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal OINAGBCE_01308 1444711.CCJF01000005_gene226 5.3e-17 93.6 Chlamydiae FbpA 3.1.21.3,3.2.1.170 ko:K01153,ko:K15524 ko00000,ko01000,ko02048 GH38 Bacteria 2JGAA@204428,COG1293@1,COG1293@2 NA|NA|NA K Domain of unknown function (DUF814) OINAGBCE_01310 264201.pc0250 5.4e-188 664.1 Chlamydiae tlcA ko:K03301 ko00000 2.A.12 Bacteria 2JFWN@204428,COG3202@1,COG3202@2 NA|NA|NA C ADP,ATP carrier protein OINAGBCE_01311 716544.wcw_1680 0.0 1487.6 Chlamydiae secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2JFRC@204428,COG0341@1,COG0341@2,COG0342@1,COG0342@2,COG1511@1,COG1511@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA OINAGBCE_01312 1444711.CCJF01000005_gene707 2.5e-205 721.8 Chlamydiae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFK9@204428,COG0608@1,COG0608@2 NA|NA|NA L exonuclease recJ OINAGBCE_01314 933262.AXAM01000022_gene3247 3.7e-135 488.4 Deltaproteobacteria ko:K06921 ko00000 Bacteria 1MWJX@1224,2WPWZ@28221,42R4K@68525,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01316 933262.AXAM01000007_gene2054 1.8e-88 333.2 Desulfobacterales ko:K07133 ko00000 Bacteria 1R3UA@1224,2MKHY@213118,2WJ04@28221,42N3U@68525,COG1373@1,COG1373@2 NA|NA|NA S AAA domain OINAGBCE_01317 867845.KI911784_gene1341 2.3e-98 365.9 Chloroflexia ko:K07496 ko00000 Bacteria 2G823@200795,3779K@32061,COG0675@1,COG0675@2 NA|NA|NA L Putative transposase DNA-binding domain OINAGBCE_01318 411464.DESPIG_00131 1.2e-66 259.6 Deltaproteobacteria guaB2 Bacteria 1QV30@1224,2WSG6@28221,42QJ9@68525,COG2452@1,COG2452@2 NA|NA|NA L Resolvase, N terminal domain OINAGBCE_01319 309801.trd_0495 4.2e-188 664.5 Thermomicrobia aceB GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010 Bacteria 27Y0V@189775,2G63R@200795,COG2225@1,COG2225@2 NA|NA|NA C Malate synthase OINAGBCE_01321 765952.PUV_09010 5.6e-07 61.6 Chlamydiae Bacteria 2JG31@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01324 1279015.KB908458_gene2497 9.9e-130 469.9 Aeromonadales tdh GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 ko:K00060 ko00260,map00260 R01465 RC00525 ko00000,ko00001,ko01000 iEC042_1314.EC042_3926,iECUMN_1333.ECUMN_4133,iPC815.YPO0060 Bacteria 1MV9A@1224,1RMNY@1236,1Y4JS@135624,COG1063@1,COG1063@2 NA|NA|NA C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate OINAGBCE_01325 526222.Desal_2895 6e-155 553.9 Desulfovibrionales kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 1MVVH@1224,2MA8W@213115,2WIU7@28221,42MM1@68525,COG0156@1,COG0156@2 NA|NA|NA E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide OINAGBCE_01326 1444711.CCJF01000005_gene1345 2.4e-25 121.7 Chlamydiae acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.6.3,2.7.8.7,3.2.1.52,4.3.1.14,5.1.1.1 ko:K00950,ko:K00997,ko:K01207,ko:K01775,ko:K06133,ko:K06925,ko:K18014 ko00310,ko00473,ko00520,ko00531,ko00770,ko00790,ko01100,ko01501,ko01502,map00310,map00473,map00520,map00531,map00770,map00790,map01100,map01501,map01502 M00126,M00628,M00841 R00022,R00401,R01625,R03030,R03503,R05963,R07809,R07810,R10831 RC00002,RC00017,RC00049,RC00285,RC00833 ko00000,ko00001,ko00002,ko01000,ko01011,ko03016 iYO844.BSU04620 Bacteria 2JGAG@204428,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein OINAGBCE_01327 716544.wcw_1184 3.7e-58 232.3 Chlamydiae pliT Bacteria 2JFPK@204428,COG4956@1,COG4956@2 NA|NA|NA S TRAM domain OINAGBCE_01328 1444712.BN1013_01720 1.1e-48 199.5 Chlamydiae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2JG73@204428,COG0691@1,COG0691@2 NA|NA|NA J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene OINAGBCE_01329 264201.pc1705 6.4e-122 444.1 Chlamydiae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JFQ0@204428,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria OINAGBCE_01330 264201.pc1706 4.2e-70 271.9 Chlamydiae recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2JG0T@204428,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP OINAGBCE_01332 903818.KI912269_gene253 6.4e-67 260.8 Acidobacteria hrtA ko:K02003,ko:K09810,ko:K09814 ko02010,map02010 M00255,M00257,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 3Y7RH@57723,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter OINAGBCE_01333 1437425.CSEC_0638 1.1e-116 426.8 Chlamydiae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2JFPM@204428,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family OINAGBCE_01334 1499967.BAYZ01000050_gene2826 2e-63 250.0 Bacteria yihY ko:K07058 ko00000 Bacteria COG1295@1,COG1295@2,COG1959@1,COG1959@2 NA|NA|NA S lipopolysaccharide transmembrane transporter activity OINAGBCE_01336 102129.Lepto7375DRAFT_2707 4.2e-46 192.2 Oscillatoriales Bacteria 1G3TW@1117,1HCQE@1150,COG3491@1,COG3491@2 NA|NA|NA C Belongs to the iron ascorbate-dependent oxidoreductase family OINAGBCE_01340 716544.wcw_1455 3.9e-94 351.7 Chlamydiae hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFS3@204428,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX OINAGBCE_01344 765952.PUV_07340 1.5e-147 529.6 Chlamydiae malQ 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 Bacteria 2JFE9@204428,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase OINAGBCE_01345 716544.wcw_0847 1.8e-33 149.1 Chlamydiae sycE Bacteria 2EA1R@1,2JGDJ@204428,33471@2 NA|NA|NA S Tir chaperone protein (CesT) family OINAGBCE_01346 765952.PUV_07780 9.1e-90 337.4 Chlamydiae lcrE ko:K04058 ko03070,map03070 M00332 ko00000,ko00001,ko00002,ko02044 Bacteria 28N7M@1,2JFPY@204428,2ZBCA@2 NA|NA|NA S type III secretion regulator YopN LcrE InvE MxiC OINAGBCE_01347 1444711.CCJF01000005_gene1747 9e-306 1055.8 Chlamydiae sctV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03230 ko03070,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 Bacteria 2JFH4@204428,COG4789@1,COG4789@2 NA|NA|NA U Type III secretion inner membrane protein SctV OINAGBCE_01348 1444711.CCJF01000005_gene1746 1.6e-114 419.5 Chlamydiae flhB ko:K02401,ko:K03229,ko:K04061,ko:K22510 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2JFD1@204428,COG1377@1,COG1377@2 NA|NA|NA U Type III secretion OINAGBCE_01349 765952.PUV_07810 1.4e-142 512.7 Chlamydiae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 2JFRS@204428,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner OINAGBCE_01350 765952.PUV_07820 5e-98 364.8 Bacteria rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria COG0116@1,COG0116@2 NA|NA|NA L 23S rRNA (guanine(2445)-N(2))-methyltransferase activity OINAGBCE_01353 765952.PUV_07330 2.3e-103 382.9 Chlamydiae CP_0628 Bacteria 2JFGS@204428,COG2912@1,COG2912@2 NA|NA|NA S Transglutaminase-like superfamily OINAGBCE_01354 264201.pc0660 4.2e-44 185.3 Chlamydiae yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 Bacteria 2JG0Y@204428,COG1561@1,COG1561@2 NA|NA|NA S Domain of unknown function (DUF1732) OINAGBCE_01355 716544.wcw_0706 2.7e-55 221.9 Chlamydiae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2JG3V@204428,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP OINAGBCE_01356 1444712.BN1013_01196 1.2e-10 72.8 Chlamydiae 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 28ZQ6@1,2JHDE@204428,2ZMF5@2 NA|NA|NA OINAGBCE_01357 1444711.CCJF01000005_gene1762 2.3e-36 159.1 Chlamydiae Bacteria 2AZKY@1,2JGQA@204428,33S81@2 NA|NA|NA OINAGBCE_01358 765952.PUV_18630 4.5e-251 874.0 Chlamydiae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Bacteria 2JFFM@204428,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation OINAGBCE_01360 765952.PUV_11560 1.3e-06 61.2 Chlamydiae yopH GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030100,GO:0030312,GO:0030313,GO:0031975,GO:0032879,GO:0044462,GO:0044464,GO:0045806,GO:0048519,GO:0048523,GO:0050764,GO:0050765,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0060627,GO:0065007,GO:0071944 ko:K04055,ko:K13740 ko05100,ko05132,map05100,map05132 ko00000,ko00001,ko02044 3.A.6.1 Bacteria 2JGJ9@204428,COG5599@1,COG5599@2 NA|NA|NA T Protein tyrosine phosphatase, catalytic domain OINAGBCE_01363 765952.PUV_18050 5e-216 757.7 Chlamydiae polA 2.7.7.7,3.1.11.5 ko:K02335,ko:K03581 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2JGZD@204428,COG0258@1,COG0258@2,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity OINAGBCE_01366 1101191.KI912577_gene3821 2.2e-18 98.2 Methylobacteriaceae higB ko:K07334 ko00000,ko02048 Bacteria 1JVP5@119045,1MZKX@1224,2UBQF@28211,COG3549@1,COG3549@2 NA|NA|NA S RelE-like toxin of type II toxin-antitoxin system HigB OINAGBCE_01367 1201290.M902_2354 7.9e-19 99.8 Bdellovibrionales ybaQ GO:0008150,GO:0009636,GO:0042221,GO:0050896 ko:K21498 ko00000,ko02048 Bacteria 1N76J@1224,2MUEY@213481,2WRPT@28221,42WQS@68525,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins OINAGBCE_01368 331113.SNE_A08800 3.2e-144 518.5 Chlamydiae cydA 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 Bacteria 2JFDB@204428,COG1271@1,COG1271@2 NA|NA|NA C oxidase, subunit OINAGBCE_01369 765952.PUV_10260 9.4e-80 303.9 Chlamydiae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120 Bacteria 2JFJV@204428,COG1294@1,COG1294@2 NA|NA|NA C oxidase, subunit II OINAGBCE_01370 908612.HMPREF9720_2405 7.4e-09 68.6 Bacteroidia 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 2FPKS@200643,4PKMY@976,COG3049@1,COG3049@2 NA|NA|NA M Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase OINAGBCE_01372 933262.AXAM01000001_gene433 1.2e-42 180.3 Desulfobacterales Bacteria 1NJ47@1224,2MJF4@213118,2WKSQ@28221,42P2D@68525,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE OINAGBCE_01374 1444712.BN1013_02331 4.3e-52 211.5 Chlamydiae rsmI_1 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2JFZE@204428,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA OINAGBCE_01375 765952.PUV_16420 3.9e-07 61.2 Chlamydiae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JHGD@204428,COG1466@1,COG1466@2 NA|NA|NA L dna polymerase III delta subunit OINAGBCE_01377 388467.A19Y_4373 4.6e-35 154.1 Oscillatoriales Bacteria 1G98C@1117,1HDSB@1150,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase OINAGBCE_01378 227377.CBU_1238 4.2e-13 80.5 Gammaproteobacteria Bacteria 1NBXS@1224,1SVGF@1236,2E9N9@1,333US@2 NA|NA|NA K Ribbon-helix-helix protein, copG family OINAGBCE_01379 765952.PUV_00580 3.1e-27 127.9 Chlamydiae cyoD ko:K02300 ko00190,ko01100,map00190,map01100 M00417 ko00000,ko00001,ko00002 3.D.4.5 Bacteria 2JGFM@204428,COG3125@1,COG3125@2 NA|NA|NA C Prokaryotic Cytochrome C oxidase subunit IV OINAGBCE_01380 1444711.CCJF01000005_gene1100 8.9e-73 280.0 Chlamydiae qoxC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12,1.9.3.1 ko:K02276,ko:K02299,ko:K02828 ko00190,ko01100,map00190,map01100 M00155,M00416,M00417 R00081,R09492 RC00016,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.5,3.D.4.6 Bacteria 2JFY3@204428,COG1845@1,COG1845@2 NA|NA|NA C Cytochrome c oxidase subunit III OINAGBCE_01381 1444711.CCJF01000005_gene1101 2.5e-302 1044.3 Chlamydiae cyoB GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0019646,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0043167,GO:0043169,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901363,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 ko:K02274,ko:K02298,ko:K02827 ko00190,ko01100,map00190,map01100 M00155,M00416,M00417 R00081,R09492,R11335 RC00016,RC00061,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6 Bacteria 2JFJW@204428,COG0843@1,COG0843@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family OINAGBCE_01382 264201.pc1189 1.3e-101 376.3 Chlamydiae cyoA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009897,GO:0009986,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071575,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12 ko:K02297,ko:K02826 ko00190,ko01100,map00190,map01100 M00416,M00417 R09492,R11335 RC00061,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1,3.D.4.5 iE2348C_1286.E2348C_0367,iJN746.PP_0812,iSB619.SA_RS05175 Bacteria 2JFR4@204428,COG1622@1,COG1622@2 NA|NA|NA C COX Aromatic Rich Motif OINAGBCE_01385 472759.Nhal_3092 1e-51 210.3 Chromatiales Bacteria 1RJ36@1224,1S7TX@1236,1X0ZI@135613,2CAM1@1,301FE@2 NA|NA|NA S Ceramidase OINAGBCE_01386 1142394.PSMK_22430 4.9e-32 144.8 Planctomycetes copZ GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0008150,GO:0009987,GO:0019725,GO:0030001,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 2.7.7.77 ko:K03752,ko:K07213,ko:K08364 ko00790,ko01100,ko04978,map00790,map01100,map04978 R11581 ko00000,ko00001,ko01000,ko02000 1.A.72.1 Bacteria 2J37Z@203682,COG2608@1,COG2608@2 NA|NA|NA P mercury ion transmembrane transporter activity OINAGBCE_01387 1449049.JONW01000007_gene4018 1.3e-10 74.3 Alphaproteobacteria ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1R3UP@1224,2TQR2@28211,COG3971@1,COG3971@2 NA|NA|NA Q hydratase decarboxylase OINAGBCE_01388 204669.Acid345_4057 9.4e-46 190.7 Acidobacteria ykfC Bacteria 3Y5IG@57723,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family OINAGBCE_01390 315456.RF_0754 2e-14 85.1 Bacteria 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 Bacteria COG1708@1,COG1708@2 NA|NA|NA S nucleotidyltransferase activity OINAGBCE_01391 315456.RF_0753 2e-24 118.6 Bacteria Bacteria COG1669@1,COG1669@2 NA|NA|NA S nucleotidyltransferase activity OINAGBCE_01392 1444711.CCJF01000005_gene1059 2.6e-37 162.5 Chlamydiae ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2JGA6@204428,COG1589@1,COG1589@2 NA|NA|NA M Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly OINAGBCE_01393 1444711.CCJF01000005_gene1057 4.6e-119 434.9 Chlamydiae murC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iIT341.HP0623,iSDY_1059.SDY_4251 Bacteria 2JFRT@204428,COG0773@1,COG0773@2 NA|NA|NA M belongs to the MurCDEF family OINAGBCE_01394 1437425.CSEC_2261 5.6e-70 271.6 Chlamydiae murG 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 GT28 Bacteria 2JFEE@204428,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) OINAGBCE_01395 264201.pc1249 6.7e-108 397.5 Chlamydiae ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2JFCC@204428,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family OINAGBCE_01396 331113.SNE_A17270 1.2e-31 143.7 Chlamydiae nlpD 3.4.24.75 ko:K08259 ko00000,ko01000,ko01002,ko01011 Bacteria 2JG8Q@204428,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif OINAGBCE_01398 264201.pc0690 1.5e-178 632.9 Chlamydiae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2JFUG@204428,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication OINAGBCE_01399 1444712.BN1013_01042 7.6e-190 670.6 Chlamydiae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K10754 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 M00289,M00295 R00382 RC00005 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JFKS@204428,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA OINAGBCE_01405 227377.CBU_0562 6.7e-120 437.6 Gammaproteobacteria ko:K07133 ko00000 Bacteria 1R3UA@1224,1SNH3@1236,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_01408 765952.PUV_04220 4.9e-31 142.1 Bacteria 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria COG2319@1,COG2319@2 NA|NA|NA S anaphase-promoting complex binding OINAGBCE_01409 765952.PUV_04210 6.8e-19 100.1 Chlamydiae nudA Bacteria 2JHDU@204428,COG4043@1,COG4043@2 NA|NA|NA OINAGBCE_01410 765952.PUV_04210 6.1e-14 85.1 Chlamydiae nudA Bacteria 2JHDU@204428,COG4043@1,COG4043@2 NA|NA|NA OINAGBCE_01411 765952.PUV_26250 5.3e-14 84.3 Chlamydiae 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2JGUM@204428,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans isomerase OINAGBCE_01412 264201.pc1452 9.7e-20 104.4 Chlamydiae Bacteria 2EU3I@1,2JGGX@204428,33MKC@2 NA|NA|NA OINAGBCE_01415 1279017.AQYJ01000028_gene2024 1.4e-20 106.7 Alteromonadaceae Bacteria 1MUBX@1224,1RMT7@1236,469B8@72275,COG4805@1,COG4805@2 NA|NA|NA S Bacterial protein of unknown function (DUF885) OINAGBCE_01417 631362.Thi970DRAFT_03186 1.3e-66 260.4 Chromatiales Bacteria 1MUMJ@1224,1RSDY@1236,1X0B5@135613,COG0399@1,COG0399@2 NA|NA|NA M Transposase zinc-binding domain OINAGBCE_01419 1444711.CCJF01000005_gene510 8.7e-104 383.6 Chlamydiae wbnF 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 R01385 RC00289 ko00000,ko00001,ko01000 Bacteria 2JFQM@204428,COG0451@1,COG0451@2 NA|NA|NA M Polysaccharide biosynthesis protein OINAGBCE_01421 1444711.CCJF01000005_gene328 4.5e-46 191.0 Chlamydiae ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JG3D@204428,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group OINAGBCE_01422 1444711.CCJF01000005_gene327 1.8e-43 182.6 Chlamydiae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JG4N@204428,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB OINAGBCE_01423 367299.JOEE01000002_gene2654 5.5e-56 224.9 Intrasporangiaceae Bacteria 2GJBP@201174,4FIDR@85021,COG0438@1,COG0438@2 NA|NA|NA M Stealth protein CR3, conserved region 3 OINAGBCE_01424 1437425.CSEC_1527 1.3e-100 373.2 Chlamydiae rfaF 2.7.1.167,2.7.7.70 ko:K02843,ko:K03272 ko00540,ko01100,map00540,map01100 M00064,M00080 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 2JFNJ@204428,COG0859@1,COG0859@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) OINAGBCE_01425 716544.wcw_1791 2.3e-62 246.1 Chlamydiae CP_1013 2.7.7.23,2.7.7.83 ko:K00972,ko:K11442 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00361,M00362 R00416 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFER@204428,COG4284@1,COG4284@2 NA|NA|NA G UDP-N-acetylglucosamine pyrophosphorylase OINAGBCE_01426 716544.wcw_1793 2.2e-102 379.0 Chlamydiae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 iIT341.HP0961,iSFV_1184.SFV_3923 Bacteria 2JFRP@204428,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase OINAGBCE_01430 716544.wcw_1797 1.2e-107 397.1 Chlamydiae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2JFGW@204428,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration OINAGBCE_01431 933262.AXAM01000024_gene724 2e-124 452.6 Desulfobacterales ko:K07133 ko00000 Bacteria 1R65E@1224,2MJXC@213118,2WMV3@28221,42MT1@68525,COG1373@1,COG1373@2 NA|NA|NA S AAA domain OINAGBCE_01432 1444711.CCJF01000005_gene1813 1.6e-140 506.1 Chlamydiae dagA_2 ko:K03310 ko00000 2.A.25 Bacteria 2JFRR@204428,COG1115@1,COG1115@2 NA|NA|NA E Sodium alanine symporter family protein OINAGBCE_01433 1286171.EAL2_c20210 9.6e-64 251.1 Eubacteriaceae lexA 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRTZ@1239,25CHW@186801,25WTS@186806,COG2865@1,COG2865@2 NA|NA|NA K Psort location Cytoplasmic, score OINAGBCE_01434 244582.JQAK01000004_gene312 1.6e-07 62.0 Rickettsiales Bacteria 1QVXZ@1224,2DPPW@1,2TWM8@28211,332XD@2,47FQB@766 NA|NA|NA S Protein of unknown function (DUF2608) OINAGBCE_01435 933262.AXAM01000028_gene3343 5.3e-83 315.1 Deltaproteobacteria ko:K07133 ko00000 Bacteria 1MWDX@1224,2WVDX@28221,4302U@68525,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_01436 331113.SNE_B24060 2.3e-122 445.7 Bacteria Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily OINAGBCE_01437 1121896.JMLU01000023_gene2291 1.5e-10 75.5 Flavobacterium GO:0005575,GO:0005576 3.4.24.3 ko:K01387,ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko02042 3.A.1.5 Bacteria 1HYZP@117743,2P055@237,4NEJ8@976,COG0747@1,COG0747@2,COG3291@1,COG3291@2,COG4447@1,COG4447@2 NA|NA|NA E PA domain OINAGBCE_01438 643648.Slip_2012 1.3e-11 75.5 Clostridia ko:K05788 ko00000,ko03032,ko03036,ko03400 Bacteria 1UJ3U@1239,24P9B@186801,COG0776@1,COG0776@2 NA|NA|NA L Protein of unknown function (DUF2442) OINAGBCE_01439 587753.EY04_21215 1.9e-166 593.6 Gammaproteobacteria Bacteria 1MW2R@1224,1RS68@1236,COG1112@1,COG1112@2 NA|NA|NA L COG1112 Superfamily I DNA and RNA helicases and helicase subunits OINAGBCE_01441 102125.Xen7305DRAFT_00000310 6.2e-14 84.0 Bacteria Bacteria COG4113@1,COG4113@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase OINAGBCE_01445 985867.AEWF01000006_gene578 1.2e-99 370.2 Rickettsiales ko:K07552 ko00000,ko02000 2.A.1.2 Bacteria 1MW19@1224,2TRQD@28211,47F3X@766,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily OINAGBCE_01446 195250.CM001776_gene3165 8.2e-28 130.2 Cyanobacteria treT 2.4.1.245 ko:K13057 ko00500,ko01100,map00500,map01100 R08946,R10525,R11306 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000 GT4 Bacteria 1GE3D@1117,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 OINAGBCE_01447 1286171.EAL2_c20210 1.7e-57 230.3 Eubacteriaceae lexA 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRTZ@1239,25CHW@186801,25WTS@186806,COG2865@1,COG2865@2 NA|NA|NA K Psort location Cytoplasmic, score OINAGBCE_01449 51511.ENSCSAVP00000002090 3e-19 104.4 Chordata 1.1.3.49 ko:K21270 ko00000,ko01000 Metazoa 38UEK@33154,3BBXZ@33208,3CRXP@33213,481AC@7711,COG2303@1,KOG1238@2759 NA|NA|NA C choline dehydrogenase activity OINAGBCE_01451 765952.PUV_17440 2.2e-43 181.8 Bacteria ko:K06940 ko00000 Bacteria COG0727@1,COG0727@2 NA|NA|NA S metal cluster binding OINAGBCE_01452 765952.PUV_23230 8.5e-19 100.1 Chlamydiae Bacteria 2ECIF@1,2JGDD@204428,336GM@2 NA|NA|NA OINAGBCE_01453 318161.Sden_2750 3.3e-85 322.0 Shewanellaceae aroF GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 Bacteria 1MU5Q@1224,1RMAA@1236,2Q8WP@267890,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) OINAGBCE_01455 264201.pc1657 2.7e-138 498.8 Chlamydiae alsT_4 ko:K03310 ko00000 2.A.25 Bacteria 2JFCM@204428,COG1115@1,COG1115@2 NA|NA|NA U Sodium:alanine symporter family OINAGBCE_01456 1444711.CCJF01000004_gene2312 1.4e-174 619.4 Chlamydiae agcS ko:K03310 ko00000 2.A.25 Bacteria 2JFP1@204428,COG1115@1,COG1115@2 NA|NA|NA E Sodium:alanine symporter family OINAGBCE_01457 3656.XP_008442817.1 4.3e-14 85.5 fabids Viridiplantae 28J6G@1,2QRIN@2759,37KDB@33090,3G8WZ@35493,4JF42@91835 NA|NA|NA OINAGBCE_01458 765952.PUV_14840 5.3e-157 561.2 Bacteria Bacteria COG1361@1,COG1361@2 NA|NA|NA M extracellular matrix structural constituent OINAGBCE_01459 1236908.wNo_05710 7.4e-31 140.6 Rickettsiales bioY ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1RH78@1224,2UE05@28211,47FIJ@766,COG1268@1,COG1268@2 NA|NA|NA S BioY family OINAGBCE_01460 1444711.CCJF01000004_gene2315 0.0 1237.6 Chlamydiae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 2JFDH@204428,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner OINAGBCE_01461 653733.Selin_1547 5.1e-153 547.7 Bacteria fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.38,4.2.1.2 ko:K00027,ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R00214,R01082 RC00105,RC00443 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS09430 Bacteria COG0114@1,COG0114@2 NA|NA|NA C fumarate hydratase activity OINAGBCE_01462 861299.J421_2319 5.5e-07 62.4 Bacteria Bacteria COG4932@1,COG4932@2,COG5624@1,COG5624@2 NA|NA|NA K beta-galactosidase activity OINAGBCE_01470 1444711.CCJF01000005_gene184 5.9e-97 361.7 Chlamydiae ybbD 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 GH3 Bacteria 2JG4V@204428,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain OINAGBCE_01472 331113.SNE_A11630 1e-75 290.4 Chlamydiae oppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2JFFJ@204428,COG0601@1,COG0601@2 NA|NA|NA P permease protein OINAGBCE_01473 1307436.PBF_03625 4.3e-71 275.0 Bacillus oppC ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,1ZC9B@1386,4H9PZ@91061,COG1173@1,COG1173@2 NA|NA|NA EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components OINAGBCE_01474 1444309.JAQG01000181_gene3453 6.2e-81 307.8 Paenibacillaceae oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,26VCV@186822,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P ABC transporter, ATP-binding protein OINAGBCE_01475 1347368.HG964410_gene7552 6e-81 307.8 Bacillus appF ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,1ZBA4@1386,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA E Belongs to the ABC transporter superfamily OINAGBCE_01476 765952.PUV_13700 4.4e-159 568.2 Chlamydiae pfp GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 ko:K00895,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2JFH8@204428,COG0205@1,COG0205@2 NA|NA|NA H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions OINAGBCE_01477 1444711.CCJF01000005_gene1651 7.9e-47 194.1 Chlamydiae yfhR3 ko:K06889 ko00000 Bacteria 2JGSN@204428,COG1073@1,COG1073@2 NA|NA|NA S Acetyl xylan esterase (AXE1) OINAGBCE_01478 765952.PUV_09750 4.2e-111 408.3 Chlamydiae mdtL GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K07552,ko:K08163,ko:K18552 br01600,ko00000,ko01504,ko02000 2.A.1.2,2.A.1.2.22,2.A.1.2.3 Bacteria 2JGF2@204428,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily OINAGBCE_01481 765952.PUV_18520 1.1e-80 306.2 Chlamydiae Bacteria 2JG02@204428,COG1225@1,COG1225@2 NA|NA|NA O Redoxin OINAGBCE_01486 716544.wcw_1074 7.1e-104 384.4 Chlamydiae waaA 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 Bacteria 2JFFN@204428,COG1519@1,COG1519@2 NA|NA|NA M Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of three 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide- 1,4'-bisphosphate precursor of lipid A. Thus generates the genus- specific LPS epitope of Chlamydia, composed of the trisaccharide alpha-Kdo-(2- 8)-alpha-Kdo-(2- 4)-alpha-Kdo OINAGBCE_01487 7070.TC007801-PA 2.4e-62 246.1 Insecta GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Arthropoda 38BYR@33154,3BEM2@33208,3CYE7@33213,3SFMM@50557,41W5W@6656,COG1820@1,KOG2177@1,KOG2177@2759,KOG3892@2759 NA|NA|NA G N-acetylglucosamine-6-phosphate deacetylase activity. It is involved in the biological process described with N-acetylglucosamine metabolic process OINAGBCE_01488 218497.CAB227 8.9e-84 317.4 Bacteria mqnE GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R09396,R10667 RC00021,RC01381,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_3391 Bacteria COG1060@1,COG1060@2 NA|NA|NA H 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity OINAGBCE_01489 1121428.DESHY_10119___1 7.5e-37 161.0 Peptococcaceae mqnA 1.21.98.1,4.2.1.151 ko:K07081,ko:K11782,ko:K11784 ko00130,ko01110,map00130,map01110 R08588,R10666 RC02329,RC03232 ko00000,ko00001,ko01000 Bacteria 1V2PX@1239,24CGN@186801,2618R@186807,COG1427@1,COG1427@2 NA|NA|NA H Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) OINAGBCE_01490 1437425.CSEC_0849 1.9e-47 196.1 Chlamydiae ubiE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0040007,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Bacteria 2JG4F@204428,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) OINAGBCE_01491 1444712.BN1013_01110 2e-50 205.7 Chlamydiae maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K06287 ko00000 Bacteria 2JG34@204428,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein OINAGBCE_01492 765952.PUV_19240 3.4e-98 365.9 Chlamydiae CP_0755 Bacteria 2JFT5@204428,COG1413@1,COG1413@2 NA|NA|NA C lyase activity OINAGBCE_01493 1382359.JIAL01000001_gene2266 3.7e-29 136.0 Acidobacteriia 1.6.5.3,3.4.21.107 ko:K00337,ko:K04771 ko00190,ko01100,ko01503,ko02020,map00190,map01100,map01503,map02020 M00144,M00728 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 3.D.1 Bacteria 2JM8V@204432,3Y7GN@57723,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain OINAGBCE_01497 1444712.BN1013_01570 0.0 1148.7 Chlamydiae ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2JFFV@204428,COG0465@1,COG0465@2 NA|NA|NA D Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins OINAGBCE_01498 765952.PUV_23710 3.4e-60 239.2 Chlamydiae tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 2JG5E@204428,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine OINAGBCE_01499 765952.PUV_23730 4.5e-54 218.8 Chlamydiae lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 Bacteria 2JG0P@204428,COG0795@1,COG0795@2 NA|NA|NA S Predicted permease YjgP/YjgQ family OINAGBCE_01500 765952.PUV_23740 1.6e-53 216.9 Chlamydiae CP_0860 ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 2JG1G@204428,COG0795@1,COG0795@2 NA|NA|NA S YjgP YjgQ family OINAGBCE_01501 1444711.CCJF01000005_gene1798 9.5e-211 740.3 Chlamydiae alr GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 2JFCJ@204428,COG0770@1,COG0770@2,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids OINAGBCE_01502 765952.PUV_21400 7e-38 165.2 Bacteria ko:K06889 ko00000 Bacteria COG1073@1,COG1073@2 NA|NA|NA S thiolester hydrolase activity OINAGBCE_01506 391612.CY0110_29414 1.9e-09 69.7 Bacteria Bacteria 2E5G8@1,3307X@2 NA|NA|NA S Immunity protein 53 OINAGBCE_01510 1382306.JNIM01000001_gene30 4.5e-40 171.8 Bacteria ko:K01066 ko00000,ko01000 Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity OINAGBCE_01513 1444711.CCJF01000004_gene2176 8.1e-155 553.5 Chlamydiae Bacteria 2JG9C@204428,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily OINAGBCE_01514 1122165.AUHS01000006_gene579 1.6e-49 202.2 Legionellales Bacteria 1JDP2@118969,1N0G8@1224,1SAFD@1236,COG4954@1,COG4954@2 NA|NA|NA S Protein of unknown function (DUF2000) OINAGBCE_01515 765952.PUV_16110 1.4e-137 496.5 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01517 665956.HMPREF1032_02864 6.1e-07 61.2 Ruminococcaceae recX GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0006282,GO:0008150,GO:0016020,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 ko:K03565 ko00000,ko03400 Bacteria 1VJ1E@1239,24QUU@186801,3WIJN@541000,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity OINAGBCE_01518 765952.PUV_20460 7.3e-227 793.5 Chlamydiae parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2JFFI@204428,COG0188@1,COG0188@2 NA|NA|NA L Belongs to the type II topoisomerase GyrA ParC subunit family OINAGBCE_01519 1437425.CSEC_0156 1.9e-256 891.7 Chlamydiae parE 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2JFGD@204428,COG0187@1,COG0187@2 NA|NA|NA L DNA topoisomerase (ATP-hydrolyzing) OINAGBCE_01521 765952.PUV_06130 1.3e-209 736.9 Chlamydiae CP_0875 ko:K06972 ko00000,ko01000,ko01002 Bacteria 2JFJS@204428,COG1026@1,COG1026@2 NA|NA|NA S Peptidase M16C associated OINAGBCE_01523 1444712.BN1013_01544 1.6e-12 80.1 Chlamydiae Bacteria 2JHHW@204428,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01524 794903.OPIT5_20525 2.4e-38 165.2 Opitutae ko:K07491 ko00000 Bacteria 3K9MH@414999,46XEX@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like OINAGBCE_01525 765952.PUV_05180 4.8e-16 90.9 Chlamydiae sycE Bacteria 2DQ8J@1,2JGFI@204428,335A5@2 NA|NA|NA S Tir chaperone protein (CesT) family OINAGBCE_01528 716544.wcw_1604 1.3e-33 149.8 Bacteria Bacteria COG1729@1,COG1729@2 NA|NA|NA S protein trimerization OINAGBCE_01529 933262.AXAM01000014_gene229 2.8e-116 425.6 Proteobacteria ko:K07133 ko00000 Bacteria 1MWDX@1224,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily) OINAGBCE_01530 765952.PUV_24350 4.7e-43 181.4 Bacteria yieH 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria COG0637@1,COG0637@2 NA|NA|NA S phosphonoacetaldehyde hydrolase activity OINAGBCE_01531 643648.Slip_1959 2.1e-42 180.3 Clostridia 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427,ko:K09388 ko00000,ko01000,ko02048 Bacteria 1UY8V@1239,24C22@186801,COG2110@1,COG2110@2,COG3465@1,COG3465@2 NA|NA|NA S Macro domain OINAGBCE_01532 933262.AXAM01000014_gene229 2.8e-116 425.6 Proteobacteria ko:K07133 ko00000 Bacteria 1MWDX@1224,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily) OINAGBCE_01533 290397.Adeh_0391 5.5e-93 347.8 Deltaproteobacteria csgG Bacteria 1NDU8@1224,2WNIN@28221,42N5V@68525,COG1462@1,COG1462@2 NA|NA|NA M Curli production assembly/transport component CsgG OINAGBCE_01534 1444711.CCJF01000005_gene1111 2.1e-238 831.6 Chlamydiae groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2JFDX@204428,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions OINAGBCE_01535 264201.pc1179 5.1e-37 160.2 Chlamydiae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2JG6X@204428,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter OINAGBCE_01536 756499.Desde_2519 1.9e-35 155.2 Peptococcaceae pepF ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,248TP@186801,260J9@186807,COG1164@1,COG1164@2 NA|NA|NA E TIGRFAM oligoendopeptidase F OINAGBCE_01538 583355.Caka_1946 7.9e-08 64.3 Opitutae Bacteria 3K82V@414999,46T8E@74201,COG1652@1,COG1652@2 NA|NA|NA S Lysin motif OINAGBCE_01539 716544.wcw_1444 3.9e-77 295.4 Chlamydiae glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02441 ko00000 Bacteria 2JFTB@204428,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family OINAGBCE_01540 1444711.CCJF01000004_gene2041 3.1e-52 211.5 Chlamydiae hldE 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2JG3S@204428,COG0615@1,COG0615@2 NA|NA|NA IM Cytidylyltransferase-like OINAGBCE_01541 1444711.CCJF01000004_gene2042 0.0 1178.7 Chlamydiae lon 3.4.21.53 ko:K01338,ko:K08675 ko04112,map04112 ko00000,ko00001,ko01000,ko01002,ko03029 Bacteria 2JFEC@204428,COG0466@1,COG0466@2 NA|NA|NA O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner OINAGBCE_01543 1444712.BN1013_01204 3e-198 698.0 Chlamydiae sthA GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019725,GO:0022857,GO:0022890,GO:0034220,GO:0036094,GO:0042592,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363,GO:1902600 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 iECED1_1282.ECED1_4669,iECs_1301.ECs4891,iZ_1308.Z5521 Bacteria 2JFJ3@204428,COG1249@1,COG1249@2 NA|NA|NA C HI0933-like protein OINAGBCE_01544 331113.SNE_A05360 4.6e-149 534.6 Chlamydiae ko:K06921 ko00000 Bacteria 2JGKE@204428,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01545 1353529.M899_3277 1.6e-66 260.0 Deltaproteobacteria 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1MVWS@1224,2WPYC@28221,42YY5@68525,COG0492@1,COG0492@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase OINAGBCE_01546 1437425.CSEC_2079 3.3e-80 305.4 Chlamydiae aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFXP@204428,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) OINAGBCE_01547 1444712.BN1013_00869 7e-21 107.1 Chlamydiae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 2JGAM@204428,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons OINAGBCE_01548 264201.pc1636 1e-164 586.6 Chlamydiae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 2JFJH@204428,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase, barrel domain OINAGBCE_01549 1444712.BN1013_00860 1.6e-35 156.4 Chlamydiae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 2JG7Y@204428,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit OINAGBCE_01551 1415778.JQMM01000001_gene260 3.4e-148 531.6 unclassified Gammaproteobacteria rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1J4I6@118884,1MU49@1224,1RMWA@1236,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA OINAGBCE_01553 331113.SNE_A10990 1.2e-115 422.9 Chlamydiae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JFHT@204428,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH OINAGBCE_01554 1444711.CCJF01000005_gene1138 6.9e-35 155.2 Chlamydiae Bacteria 2DZIQ@1,2JGQ8@204428,33QR0@2 NA|NA|NA OINAGBCE_01555 1444711.CCJF01000005_gene1135 4.3e-46 191.8 Chlamydiae otsB2 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030312,GO:0034637,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0071704,GO:0071944,GO:1901576 3.1.3.12,3.2.1.28 ko:K01087,ko:K01194,ko:K06438 ko00500,ko01100,map00500,map01100 R00010,R02778 RC00017,RC00049 ko00000,ko00001,ko00537,ko01000 GH37 Bacteria 2JG55@204428,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase OINAGBCE_01557 765952.PUV_07450 2.4e-55 222.2 Chlamydiae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 2JG18@204428,COG0572@1,COG0572@2 NA|NA|NA F nucleoside kinase activity OINAGBCE_01558 1444711.CCJF01000005_gene1130 7.4e-32 143.7 Chlamydiae MA20_05485 Bacteria 2JG9H@204428,COG5465@1,COG5465@2 NA|NA|NA S Putative bacterial sensory transduction regulator OINAGBCE_01559 1444711.CCJF01000005_gene1129 5.4e-59 234.2 Chlamydiae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2JFVY@204428,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III, epsilon OINAGBCE_01560 743525.TSC_c21990 7.6e-48 197.6 Deinococcus-Thermus mqnD ko:K07083,ko:K11785 ko00130,ko01110,map00130,map01110 R08589 RC02330 ko00000,ko00001,ko01000 Bacteria 1WICQ@1297,COG2107@1,COG2107@2 NA|NA|NA S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) OINAGBCE_01561 1283287.KB822579_gene2142 1.4e-08 66.6 Propionibacteriales pfs 3.2.2.1,3.2.2.9 ko:K01239,ko:K01243 ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230 M00034,M00609 R00194,R01245,R01273,R01401,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko00002,ko01000 Bacteria 2IMZ7@201174,4DQZA@85009,COG0775@1,COG0775@2 NA|NA|NA F Phosphorylase superfamily OINAGBCE_01562 765952.PUV_25070 1.4e-82 313.5 Chlamydiae Bacteria 2JFSW@204428,COG1409@1,COG1409@2 NA|NA|NA S Purple acid Phosphatase, N-terminal domain OINAGBCE_01563 402626.Rpic_4134 1e-106 393.7 Burkholderiaceae ko:K06921 ko00000 Bacteria 1K490@119060,1R8WG@1224,2VQHA@28216,COG1672@1,COG1672@2 NA|NA|NA S PFAM Archaeal ATPase OINAGBCE_01564 1230343.CANP01000048_gene3726 2.4e-81 310.1 Bacteria Bacteria COG5492@1,COG5492@2 NA|NA|NA N domain, Protein OINAGBCE_01565 1444711.CCJF01000005_gene1730 5.8e-94 351.3 Chlamydiae brnQ ko:K03311 ko00000 2.A.26 Bacteria 2JFJA@204428,COG1114@1,COG1114@2 NA|NA|NA E Branched-chain amino acid transport system OINAGBCE_01566 1437425.CSEC_1047 5.6e-11 76.6 Chlamydiae lepB_1 2.1.1.80,3.1.1.61,3.1.21.3 ko:K01153,ko:K13924,ko:K15492 ko02020,ko02030,ko05134,map02020,map02030,map05134 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02048 Bacteria 2JFZX@204428,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation OINAGBCE_01568 1444712.BN1013_02447 2.4e-20 104.4 Bacteria Bacteria 2EH1B@1,33ATB@2 NA|NA|NA OINAGBCE_01569 1444712.BN1013_02446 3.3e-98 364.8 Bacteria Bacteria COG4185@1,COG4185@2 NA|NA|NA OINAGBCE_01570 204773.HEAR3422 1e-50 207.2 Oxalobacteraceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY5S@1224,2VQBX@28216,473Q3@75682,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively OINAGBCE_01571 264201.pc1475 3e-116 426.4 Chlamydiae gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria 2JGSP@204428,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II and III secretion system protein OINAGBCE_01572 264201.pc1401 9.6e-89 334.3 Chlamydiae pkn5 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 2JFS0@204428,COG0515@1,COG0515@2,COG2208@1,COG2208@2 NA|NA|NA KLT Serine threonine protein kinase OINAGBCE_01573 264201.pc1400 6.9e-51 208.4 Chlamydiae epaO ko:K02416,ko:K02417,ko:K03225 ko02030,ko02040,ko03070,map02030,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2JG37@204428,COG1886@1,COG1886@2 NA|NA|NA N Type III flagellar switch regulator (C-ring) FliN C-term OINAGBCE_01574 716544.wcw_1618 5.5e-10 72.4 Chlamydiae Bacteria 2EB7P@1,2JGG6@204428,33588@2 NA|NA|NA OINAGBCE_01575 1444711.CCJF01000005_gene773 1.4e-26 126.3 Chlamydiae Bacteria 2FDSZ@1,2JG7N@204428,31B3S@2 NA|NA|NA S YscO-like protein OINAGBCE_01576 765952.PUV_05660 3.1e-200 704.5 Chlamydiae fliI 3.6.3.14 ko:K02412,ko:K03224 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko01000,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2JFQR@204428,COG1157@1,COG1157@2 NA|NA|NA NU Type III OINAGBCE_01577 1437425.CSEC_0103 4.4e-23 115.2 Chlamydiae Bacteria 2BYXK@1,2JG7P@204428,32R42@2 NA|NA|NA OINAGBCE_01578 716544.wcw_1614 3.6e-31 141.4 Chlamydiae Bacteria 2JG1R@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01579 1444711.CCJF01000005_gene776 8.4e-13 79.7 Chlamydiae sctF Bacteria 2E8F8@1,2JGCX@204428,332TK@2 NA|NA|NA S Family of unknown function (DUF5407) OINAGBCE_01580 1437425.CSEC_0106 3e-11 74.3 Chlamydiae sctE Bacteria 2DPKT@1,2JGFD@204428,332JN@2 NA|NA|NA S Family of unknown function (DUF5398) OINAGBCE_01581 716544.wcw_1611 4.2e-129 468.4 Chlamydiae sctD Bacteria 2JFPC@204428,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain OINAGBCE_01583 716544.wcw_0201 3.4e-59 235.0 Chlamydiae exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2JG1A@204428,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family OINAGBCE_01584 264201.pc1546 1e-27 132.1 Chlamydiae ygfZ 3.1.21.3 ko:K01153,ko:K02498 ko00000,ko01000,ko02048 Bacteria 2JGAC@204428,COG0457@1,COG0457@2,COG1729@1,COG1729@2,COG3071@1,COG3071@2 NA|NA|NA H Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division OINAGBCE_01585 1444711.CCJF01000004_gene1838 4.1e-15 87.8 Chlamydiae hctA Bacteria 2CG3Q@1,2JGDW@204428,336U3@2 NA|NA|NA S Histone H1-like protein Hc1 OINAGBCE_01586 1444712.BN1013_00208 1.8e-113 416.4 Chlamydiae rumA 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 2JFX6@204428,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family OINAGBCE_01587 264201.pc1543 3.7e-23 114.4 Chlamydiae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2JGA9@204428,COG1862@1,COG1862@2 NA|NA|NA U The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF- YajC-YidC subcomplex facilitates these functions OINAGBCE_01588 1444711.CCJF01000004_gene1848 4.8e-99 368.2 Chlamydiae Bacteria 2JFSW@204428,COG1409@1,COG1409@2 NA|NA|NA S Purple acid Phosphatase, N-terminal domain OINAGBCE_01589 264201.pc1535 1.4e-184 652.9 Chlamydiae htpG GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701 ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Bacteria 2JFDI@204428,COG0326@1,COG0326@2 NA|NA|NA O chaperone protein htpG OINAGBCE_01590 985867.AEWF01000003_gene809 1.4e-55 223.4 Rickettsiales Bacteria 1MWMM@1224,2TQX8@28211,47FDP@766,COG5459@1,COG5459@2 NA|NA|NA J Mitochondrial small ribosomal subunit Rsm22 OINAGBCE_01591 1437425.CSEC_0065 1.9e-146 526.2 Chlamydiae nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFG4@204428,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source OINAGBCE_01592 331113.SNE_A22480 2.8e-136 491.9 Chlamydiae ko:K07133 ko00000 Bacteria 2JGTG@204428,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_01593 331113.SNE_A22770 2.7e-42 179.5 Chlamydiae Bacteria 2JH6V@204428,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 OINAGBCE_01594 331113.SNE_A22770 1.7e-42 179.9 Chlamydiae Bacteria 2JH6V@204428,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 OINAGBCE_01595 331113.SNE_A22770 2.1e-42 179.5 Chlamydiae Bacteria 2JH6V@204428,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 OINAGBCE_01596 765952.PUV_02920 1.7e-92 345.9 Chlamydiae amn 2.4.2.3,3.2.2.4 ko:K00757,ko:K01241 ko00230,ko00240,ko00983,ko01100,map00230,map00240,map00983,map01100 R00182,R01876,R02484,R08229 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2JFWB@204428,COG2820@1,COG2820@2 NA|NA|NA F AMP nucleosidase OINAGBCE_01597 1444712.BN1013_00184 1.3e-81 309.3 Chlamydiae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 ko:K02356 ko00000,ko03012 Bacteria 2JFP3@204428,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase OINAGBCE_01603 1144932.ATTF01000022_gene36 1.5e-21 108.6 unclassified Alphaproteobacteria trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1MUN1@1224,2TSIZ@28211,4BPYG@82117,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family OINAGBCE_01604 1444711.CCJF01000005_gene1767 3.8e-38 164.5 Chlamydiae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG56@204428,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site OINAGBCE_01605 1437425.CSEC_2291 3.9e-53 214.9 Chlamydiae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2JFYJ@204428,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids OINAGBCE_01608 1444711.CCJF01000004_gene2492 3.2e-277 961.1 Chlamydiae Bacteria 2JGU9@204428,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase OINAGBCE_01610 344747.PM8797T_01704 1.1e-100 373.6 Planctomycetes metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXCJ@203682,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme OINAGBCE_01611 1444711.CCJF01000005_gene216 8.7e-31 140.2 Chlamydiae murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2JG0N@204428,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis OINAGBCE_01613 933262.AXAM01000024_gene724 6.3e-123 447.6 Desulfobacterales ko:K07133 ko00000 Bacteria 1R65E@1224,2MJXC@213118,2WMV3@28221,42MT1@68525,COG1373@1,COG1373@2 NA|NA|NA S AAA domain OINAGBCE_01614 716544.wcw_0775 4.4e-16 90.9 Chlamydiae yuxK Bacteria 2JG92@204428,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 OINAGBCE_01615 998674.ATTE01000001_gene719 2.7e-95 355.9 Thiotrichales Bacteria 1MXWY@1224,1RXR7@1236,46312@72273,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family OINAGBCE_01616 331113.SNE_A20890 9.6e-69 267.3 Bacteria Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family OINAGBCE_01619 5888.CAK85595 1.4e-07 64.3 Ciliophora Eukaryota 3ZFE1@5878,KOG0297@1,KOG0297@2759 NA|NA|NA O zinc finger of C3HC4-type, RING OINAGBCE_01621 858215.Thexy_0042 2e-125 456.1 Thermoanaerobacterales 2.7.7.49 ko:K00986 ko00000,ko01000 Bacteria 1TP9A@1239,248M4@186801,42EZK@68295,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) OINAGBCE_01623 716544.wcw_1853 1.2e-24 119.8 Chlamydiae Z012_05445 2.3.1.189 ko:K15520 ko00000,ko01000 Bacteria 2JHDR@204428,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain OINAGBCE_01626 1141662.OOA_01220 8.8e-11 73.2 Gammaproteobacteria Bacteria 1NN24@1224,1SUV6@1236,2EKKN@1,33EAG@2 NA|NA|NA OINAGBCE_01627 765952.PUV_04040 1.3e-26 126.7 Chlamydiae MA20_05800 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K09778 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 Bacteria 2JG6H@204428,COG2121@1,COG2121@2 NA|NA|NA S Domain of unknown function (DUF374) OINAGBCE_01628 765952.PUV_04050 2.1e-72 279.6 Chlamydiae lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478,iIT341.HP0867 Bacteria 2JFD2@204428,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell OINAGBCE_01629 264201.pc1311 1.5e-43 183.0 Chlamydiae lpxB 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 Bacteria 2JG3N@204428,COG3952@1,COG3952@2 NA|NA|NA S Lipid A Biosynthesis N-terminal domain OINAGBCE_01630 765952.PUV_04070 2.1e-70 272.3 Chlamydiae arnC 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2JFMX@204428,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 OINAGBCE_01631 1437425.CSEC_1350 5.7e-113 414.5 Chlamydiae pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2JFVS@204428,COG0617@1,COG0617@2 NA|NA|NA H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control OINAGBCE_01632 765952.PUV_25830 1.4e-193 682.6 Chlamydiae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iSBO_1134.SBO_3206 Bacteria 2JFS2@204428,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate OINAGBCE_01633 1444712.BN1013_00112 8.2e-53 214.2 Chlamydiae cyoA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009897,GO:0009986,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071575,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12 ko:K02297,ko:K02826 ko00190,ko01100,map00190,map01100 M00416,M00417 R09492,R11335 RC00061,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1,3.D.4.5 iE2348C_1286.E2348C_0367,iJN746.PP_0812,iSB619.SA_RS05175 Bacteria 2JFR4@204428,COG1622@1,COG1622@2 NA|NA|NA C COX Aromatic Rich Motif OINAGBCE_01634 765952.PUV_03670 3.6e-53 215.7 Chlamydiae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2JG6J@204428,COG0658@1,COG0658@2 NA|NA|NA S Competence protein OINAGBCE_01635 331113.SNE_A07320 5.4e-26 124.8 Bacteria yveB 2.7.4.29 ko:K19803 R11186 RC00002 ko00000,ko01000,ko01005 Bacteria COG0671@1,COG0671@2 NA|NA|NA I phosphatidate phosphatase activity OINAGBCE_01636 716544.wcw_0678 6.9e-148 530.8 Chlamydiae ypwA 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 2JFNU@204428,COG2317@1,COG2317@2 NA|NA|NA E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues OINAGBCE_01637 1444711.CCJF01000005_gene1800 7.3e-162 577.8 Chlamydiae CP_0861 Bacteria 2DBSG@1,2JFD6@204428,2ZAS8@2 NA|NA|NA OINAGBCE_01639 331113.SNE_A10450 5.3e-175 622.1 Chlamydiae oppA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2JFKE@204428,COG4166@1,COG4166@2 NA|NA|NA E transmembrane transport OINAGBCE_01640 1118054.CAGW01000080_gene2799 2.8e-118 432.6 Paenibacillaceae ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,26QGU@186822,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter substrate-binding protein OINAGBCE_01641 1444711.CCJF01000004_gene2177 1.1e-40 173.3 Bacteria Bacteria COG3247@1,COG3247@2 NA|NA|NA U response to pH OINAGBCE_01642 765952.PUV_21070 8.9e-57 226.5 Chlamydiae tadA 3.5.4.3,3.5.4.33 ko:K01487,ko:K11991 ko00230,ko01100,map00230,map01100 R01676,R10223 RC00204,RC00477 ko00000,ko00001,ko01000,ko03016 Bacteria 2JH9C@204428,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase OINAGBCE_01643 716544.wcw_1331 5.7e-130 470.7 Chlamydiae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accA Bacteria 2JFES@204428,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA OINAGBCE_01644 264201.pc1165 8.8e-89 334.0 Chlamydiae ko:K16291 ko00000,ko01002,ko01011 Bacteria 2JFN1@204428,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain OINAGBCE_01645 1444711.CCJF01000005_gene1121 2.3e-38 164.9 Chlamydiae hup ko:K03530,ko:K04764 ko00000,ko03032,ko03036,ko03400 Bacteria 2JG67@204428,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family OINAGBCE_01646 716544.wcw_1334 2.2e-87 328.9 Chlamydiae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 2JFHY@204428,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) OINAGBCE_01653 1444711.CCJF01000004_gene2192 4.1e-41 174.1 Chlamydiae nuoA 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JH2S@204428,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_01654 1444711.CCJF01000004_gene2193 5.4e-73 280.4 Chlamydiae nuoB 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JFPN@204428,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_01655 1437425.CSEC_0601 1.1e-45 189.5 Chlamydiae nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iAF987.Gmet_3353 Bacteria 2JGZJ@204428,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_01656 1444711.CCJF01000004_gene2195 5.5e-172 610.5 Chlamydiae nuoD 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGTU@204428,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_01657 1444711.CCJF01000004_gene2196 1e-57 229.6 Chlamydiae nuoE 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGV6@204428,COG1905@1,COG1905@2 NA|NA|NA C Thioredoxin-like [2Fe-2S] ferredoxin OINAGBCE_01658 765952.PUV_26550 9.9e-196 689.5 Chlamydiae nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGT3@204428,COG1894@1,COG1894@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain OINAGBCE_01659 1444711.CCJF01000004_gene2198 1.4e-253 882.5 Chlamydiae nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JFP6@204428,COG1034@1,COG1034@2 NA|NA|NA C Molybdopterin oxidoreductase Fe4S4 domain OINAGBCE_01664 765952.PUV_26530 6.5e-139 500.4 Chlamydiae nuoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGUX@204428,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone OINAGBCE_01665 1444711.CCJF01000004_gene2200 1.3e-44 186.0 Chlamydiae nuoI GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 ko:K00337,ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iNJ661.Rv3153 Bacteria 2JGNI@204428,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient OINAGBCE_01666 1444711.CCJF01000004_gene2201 1.4e-39 169.5 Chlamydiae nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2JGZW@204428,COG0839@1,COG0839@2 NA|NA|NA C Belongs to the complex I subunit 6 family OINAGBCE_01667 59196.RICGR_1480 2.6e-22 111.3 Legionellales vapL ko:K21498 ko00000,ko02048 Bacteria 1JG5W@118969,1N76J@1224,1SCYV@1236,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins OINAGBCE_01670 1268635.Loa_00219 7.3e-144 517.3 Legionellales ko:K07133 ko00000 Bacteria 1JFUU@118969,1MWDX@1224,1RYD6@1236,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_01674 765952.PUV_04160 4.5e-139 501.5 Chlamydiae der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2JFJG@204428,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis OINAGBCE_01676 765952.PUV_04110 1.2e-265 923.3 Chlamydiae CP_1034 Bacteria 2JFGJ@204428,COG0553@1,COG0553@2 NA|NA|NA KL SNF2 family N-terminal domain OINAGBCE_01677 1444711.CCJF01000005_gene754 3.9e-143 514.6 Chlamydiae ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2JFCH@204428,COG0686@1,COG0686@2 NA|NA|NA C Alanine dehydrogenase/PNT, N-terminal domain OINAGBCE_01679 1444712.BN1013_01371 9.9e-126 458.4 Chlamydiae smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2JFIW@204428,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning OINAGBCE_01680 1121106.JQKB01000029_gene4884 8.9e-125 453.8 Proteobacteria Bacteria 1MWIV@1224,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic OINAGBCE_01681 1397528.Q671_04880 8.6e-94 350.1 Oceanospirillales Bacteria 1MVU2@1224,1RNUA@1236,1XIS1@135619,COG1484@1,COG1484@2 NA|NA|NA L DNA replication protein OINAGBCE_01682 933262.AXAM01000012_gene1803 5.8e-129 467.6 Proteobacteria ko:K07133 ko00000 Bacteria 1R9U4@1224,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily OINAGBCE_01683 1444711.CCJF01000005_gene1770 3.7e-161 574.7 Chlamydiae ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2JFVZ@204428,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY OINAGBCE_01684 1444711.CCJF01000005_gene1769 2.1e-25 121.7 Chlamydiae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2JGCH@204428,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family OINAGBCE_01685 768671.ThimaDRAFT_4442 1.3e-19 105.9 Chromatiales Bacteria 1MVV1@1224,1RP75@1236,1WWJF@135613,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain OINAGBCE_01686 86106.I862_04800 1.4e-33 149.1 Rickettsiales mazG 3.6.1.66 ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 Bacteria 1Q92Q@1224,2VD87@28211,47GFU@766,COG1694@1,COG1694@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase domain OINAGBCE_01687 1341646.CBMO010000093_gene5733 4.2e-09 67.0 Mycobacteriaceae Bacteria 239QD@1762,2II1U@201174,COG1942@1,COG1942@2 NA|NA|NA S Tautomerase enzyme OINAGBCE_01688 331113.SNE_A08570 3.9e-108 398.3 Chlamydiae ko:K06873 ko00000 Bacteria 2JFTG@204428,COG0857@1,COG0857@2 NA|NA|NA C DRTGG domain OINAGBCE_01689 765952.PUV_12670 3.4e-37 161.4 Chlamydiae mutT 3.6.1.55,3.6.1.67 ko:K03574,ko:K19965 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2JG84@204428,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain OINAGBCE_01690 1444711.CCJF01000004_gene2180 4.6e-99 367.9 Chlamydiae map 1.17.1.1,3.4.11.18 ko:K00523,ko:K01265 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFXB@204428,COG0024@1,COG0024@2 NA|NA|NA E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) OINAGBCE_01691 716544.wcw_0945 7.4e-39 167.9 Chlamydiae Bacteria 2JGF3@204428,COG4221@1,COG4221@2 NA|NA|NA C KR domain OINAGBCE_01694 331113.SNE_A12700 2.8e-110 405.6 Chlamydiae ko:K07133 ko00000 Bacteria 2JH9D@204428,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_01695 765952.PUV_12710 1e-49 204.9 Chlamydiae 2.1.1.21,6.3.5.4 ko:K01953,ko:K22081 ko00250,ko00680,ko01100,ko01110,ko01120,map00250,map00680,map01100,map01110,map01120 R00578,R01586 RC00010,RC00554 ko00000,ko00001,ko01000,ko01002 Bacteria 2JFPW@204428,COG0367@1,COG0367@2 NA|NA|NA E Glutamine amidotransferase domain OINAGBCE_01697 1444711.CCJF01000004_gene2475 9.3e-25 120.9 Chlamydiae ko:K07052 ko00000 Bacteria 2JGC1@204428,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity OINAGBCE_01698 688269.Theth_1899 5.5e-47 195.3 Thermotogae ko:K13963 ko05146,map05146 ko00000,ko00001 Bacteria 2GDUM@200918,COG4826@1,COG4826@2 NA|NA|NA O SERine Proteinase INhibitors OINAGBCE_01699 1437425.CSEC_0846 1.7e-57 229.6 Chlamydiae prpC 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 2JG4D@204428,COG0631@1,COG0631@2 NA|NA|NA T Serine threonine protein phosphatase OINAGBCE_01700 264201.pc0721 1.1e-92 347.1 Chlamydiae 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2JFR6@204428,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V OINAGBCE_01702 1444712.BN1013_00066 5.1e-24 117.9 Bacteria GO:0005575,GO:0005576,GO:0005615,GO:0044421 Bacteria COG2335@1,COG2335@2 NA|NA|NA M COG2335, Secreted and surface protein containing fasciclin-like repeats OINAGBCE_01703 1034943.BN1094_02732 2.7e-72 279.3 Legionellales ybdK ko:K06048 ko00000,ko01000 Bacteria 1JCFE@118969,1MX4N@1224,1RRZ1@1236,COG2170@1,COG2170@2 NA|NA|NA H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity OINAGBCE_01704 264201.pc1772 1.4e-104 386.3 Chlamydiae mdh GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFTH@204428,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate OINAGBCE_01705 331113.SNE_A07020 2.1e-144 518.8 Chlamydiae gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2JFPR@204428,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain OINAGBCE_01707 1444712.BN1013_01033 1.3e-47 196.8 Chlamydiae Bacteria 28JQF@1,2JFW5@204428,2Z9GB@2 NA|NA|NA OINAGBCE_01708 1444711.CCJF01000005_gene1282 8.9e-55 221.1 Chlamydiae mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 Bacteria 2JG6M@204428,COG0665@1,COG0665@2 NA|NA|NA E Oxidoreductase OINAGBCE_01710 1444712.BN1013_02216 2.4e-32 145.2 Bacteria Bacteria 2DQ8V@1,32UNN@2 NA|NA|NA OINAGBCE_01711 1444712.BN1013_02215 5.7e-73 281.2 Bacteria Bacteria 2CAB8@1,3373Z@2 NA|NA|NA OINAGBCE_01713 10224.XP_006812581.1 7.7e-13 82.0 Bilateria PTPN13 GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005886,GO:0006464,GO:0006470,GO:0006629,GO:0006644,GO:0006650,GO:0006661,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0014066,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0019637,GO:0023051,GO:0030027,GO:0030496,GO:0031252,GO:0031974,GO:0031981,GO:0034097,GO:0035335,GO:0036211,GO:0036312,GO:0042221,GO:0042578,GO:0042995,GO:0043005,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043548,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0046488,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0071944,GO:0090407,GO:0097458,GO:0120025,GO:0140096,GO:1901564,GO:1901576,GO:1902531 3.1.3.48 ko:K02374,ko:K18039 ko04210,map04210 ko00000,ko00001,ko01000,ko01009 Metazoa 38CNY@33154,3BKRY@33208,3CWKT@33213,COG5599@1,KOG0792@2759,KOG1945@1,KOG1945@2759 NA|NA|NA T protein tyrosine phosphatase activity OINAGBCE_01716 290317.Cpha266_0645 5.1e-154 550.8 Bacteria Bacteria COG1672@1,COG1672@2 NA|NA|NA OINAGBCE_01723 1444711.CCJF01000005_gene827 1.3e-201 709.1 Chlamydiae asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iSDY_1059.SDY_2327 Bacteria 2JFVT@204428,COG0017@1,COG0017@2 NA|NA|NA J tRNA synthetases class II (D, K and N) OINAGBCE_01724 1444712.BN1013_01434 1.3e-101 376.3 Chlamydiae nfo GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFHU@204428,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin OINAGBCE_01725 1444711.CCJF01000005_gene825 6.3e-110 404.8 Chlamydiae murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2JFGY@204428,COG0728@1,COG0728@2 NA|NA|NA S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane OINAGBCE_01726 227377.CBU_0609 3e-73 282.3 Gammaproteobacteria mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1RIKN@1224,1S678@1236,COG1577@1,COG1577@2 NA|NA|NA I GHMP kinases N terminal domain OINAGBCE_01727 1232683.ADIMK_2707 2.9e-58 232.3 Alteromonadaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1NF04@1224,1RPXQ@1236,46C8E@72275,COG1577@1,COG1577@2 NA|NA|NA I GHMP kinases C terminal OINAGBCE_01728 1278309.KB907099_gene2466 2.1e-89 335.9 Oceanospirillales mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1N5EZ@1224,1S19T@1236,1XJ0Z@135619,COG3407@1,COG3407@2 NA|NA|NA I GHMP kinases N terminal domain OINAGBCE_01729 264201.pc1367 1.2e-74 286.2 Chlamydiae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFKA@204428,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit OINAGBCE_01731 1437425.CSEC_0142 3.3e-115 422.5 Chlamydiae Bacteria 2JFK8@204428,COG2604@1,COG2604@2 NA|NA|NA S Protein of unknown function DUF115 OINAGBCE_01732 264201.pc0387 1.4e-166 592.8 Chlamydiae uhpC GO:0000160,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K02445,ko:K07783 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.4.3,2.A.1.4.4,2.A.1.4.6 Bacteria 2JFUY@204428,COG2271@1,COG2271@2 NA|NA|NA G Hexose phosphate transport protein OINAGBCE_01734 1444712.BN1013_01429 3.3e-15 88.2 Chlamydiae CP_0160 Bacteria 2JGDE@204428,COG4096@1,COG4096@2 NA|NA|NA V Type I restriction enzyme R protein N terminus (HSDR_N) OINAGBCE_01735 1437425.CSEC_0135 9.1e-52 210.3 Chlamydiae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808,ko:K05809 ko00000,ko03009 Bacteria 2JFY2@204428,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase OINAGBCE_01737 1118054.CAGW01000017_gene4396 7.8e-09 67.4 Paenibacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,26S90@186822,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination OINAGBCE_01743 765952.PUV_07570 2.1e-44 186.0 Chlamydiae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2JFIQ@204428,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region OINAGBCE_01746 1444712.BN1013_01757 1.6e-16 94.0 Chlamydiae Bacteria 2EM3E@1,2JGHH@204428,33ESX@2 NA|NA|NA OINAGBCE_01747 583355.Caka_2755 1.1e-47 197.2 Opitutae ko:K03466,ko:K07088 ko00000,ko03036 3.A.12 Bacteria 3K77N@414999,46SPM@74201,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein OINAGBCE_01748 1444711.CCJF01000005_gene1645 1.4e-19 103.6 Chlamydiae Bacteria 2JGYR@204428,COG4249@1,COG4249@2 NA|NA|NA S Caspase domain OINAGBCE_01749 1444711.CCJF01000005_gene1479 3.4e-53 214.9 Chlamydiae Bacteria 2JGTS@204428,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein OINAGBCE_01751 5888.CAK78209 5.7e-07 62.4 Eukaryota 2.7.11.1 ko:K11481 ko04114,ko04914,map04114,map04914 ko00000,ko00001,ko01000,ko01001,ko01009,ko03036 Eukaryota KOG0580@1,KOG0580@2759 NA|NA|NA H histone serine kinase activity OINAGBCE_01752 5888.CAK65621 8.6e-14 85.1 Ciliophora PRPF4B GO:0000166,GO:0000245,GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005737,GO:0006139,GO:0006376,GO:0006396,GO:0006397,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0008380,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010564,GO:0010604,GO:0010628,GO:0010948,GO:0016043,GO:0016070,GO:0016071,GO:0016301,GO:0016310,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019219,GO:0019222,GO:0019538,GO:0019725,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030003,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032386,GO:0032388,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033120,GO:0033157,GO:0034622,GO:0034641,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0042306,GO:0042307,GO:0042493,GO:0042592,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043484,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045292,GO:0045786,GO:0045935,GO:0046483,GO:0046822,GO:0046824,GO:0048024,GO:0048026,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050684,GO:0050685,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051050,GO:0051171,GO:0051173,GO:0051222,GO:0051223,GO:0051252,GO:0051254,GO:0051716,GO:0051726,GO:0055080,GO:0055082,GO:0060255,GO:0060341,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0070316,GO:0070317,GO:0071013,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090087,GO:0090304,GO:0090316,GO:0097159,GO:0097367,GO:0140096,GO:1900180,GO:1900182,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1903311,GO:1903313,GO:1903827,GO:1903829,GO:1904589,GO:1904591,GO:1904951,GO:1905744,GO:1905746,GO:1990904 2.7.11.1 ko:K08827 ko00000,ko01000,ko01001,ko03041 Eukaryota 3ZASD@5878,KOG0667@1,KOG0670@2759 NA|NA|NA A Protein kinase domain OINAGBCE_01754 765952.PUV_22770 3.7e-43 182.2 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_01755 1123248.KB893381_gene1123 2.3e-06 61.6 Bacteroidetes Bacteria 4NPS4@976,COG1520@1,COG1520@2 NA|NA|NA C PQQ enzyme repeat OINAGBCE_01756 1499967.BAYZ01000016_gene6567 4.5e-109 401.4 unclassified Bacteria ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2NPB2@2323,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family OINAGBCE_01757 331113.SNE_A18680 5.2e-108 398.3 Chlamydiae merA1 Bacteria 2JGTZ@204428,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain OINAGBCE_01759 765952.PUV_18150 1.3e-14 84.7 Chlamydiae rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGJK@204428,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family OINAGBCE_01760 1444712.BN1013_02167 2.1e-20 106.7 Chlamydiae licD ko:K07271 ko00000,ko01000 Bacteria 2JHA6@204428,COG3475@1,COG3475@2 NA|NA|NA M LicD family OINAGBCE_01761 264201.pc0794 9.2e-153 546.6 Chlamydiae tgt 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 2JFWK@204428,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) OINAGBCE_01762 1444711.CCJF01000005_gene1816 4.1e-44 184.9 Chlamydiae ypdP ko:K09125 ko00000 Bacteria 2JG7K@204428,COG1738@1,COG1738@2 NA|NA|NA S Putative vitamin uptake transporter OINAGBCE_01763 1397528.Q671_04880 2.2e-94 352.1 Oceanospirillales Bacteria 1MVU2@1224,1RNUA@1236,1XIS1@135619,COG1484@1,COG1484@2 NA|NA|NA L DNA replication protein OINAGBCE_01764 1121106.JQKB01000029_gene4884 9.6e-122 443.7 Proteobacteria Bacteria 1MWIV@1224,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic OINAGBCE_01765 1174528.JH992893_gene5990 1.8e-70 272.7 Cyanobacteria Bacteria 1G4S8@1117,COG1028@1,COG1028@2 NA|NA|NA IQ COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) OINAGBCE_01766 331113.SNE_A10400 2.7e-30 138.3 Chlamydiae prfA3 Bacteria 2JH63@204428,COG1186@1,COG1186@2 NA|NA|NA J RF-1 domain OINAGBCE_01767 381046.XP_002551571.1 1.5e-16 93.2 Saccharomycetaceae GO:0000086,GO:0000278,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005730,GO:0005737,GO:0006325,GO:0006342,GO:0006355,GO:0006464,GO:0006508,GO:0006807,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0012505,GO:0016043,GO:0016458,GO:0016485,GO:0016787,GO:0016926,GO:0016929,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019783,GO:0022402,GO:0030466,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0034399,GO:0036211,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0045814,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0051604,GO:0060255,GO:0065007,GO:0070011,GO:0070013,GO:0070122,GO:0070137,GO:0070138,GO:0070139,GO:0070140,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0140096,GO:1901564,GO:1902679,GO:1903047,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.22.68 ko:K08592 ko00000,ko01000,ko01002,ko04121 Fungi 38HPZ@33154,3P3UZ@4751,3QW8A@4890,3RS0P@4891,3S05I@4893,COG5160@1,KOG0778@2759 NA|NA|NA O to Saccharomyces cerevisiae ULP1 (YPL020C) OINAGBCE_01768 28583.AMAG_17143T0 1.5e-06 63.2 Fungi Fungi 38GAW@33154,3NZI3@4751,COG0553@1,KOG0384@2759 NA|NA|NA B Chromatin organization modifier domain OINAGBCE_01770 10224.XP_006815744.1 1.3e-06 62.0 Bilateria ANKRD61 Metazoa 392DF@33154,3BKHN@33208,3D04Q@33213,COG0666@1,KOG4177@2759 NA|NA|NA M Ankyrin repeat OINAGBCE_01771 378806.STAUR_0292 8.9e-09 67.8 Bacteria ysnE ko:K03829 ko00000,ko01000 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase OINAGBCE_01772 1444712.BN1013_00626 6e-63 247.7 Bacteria 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator OINAGBCE_01774 443144.GM21_0294 7.5e-29 133.3 Deltaproteobacteria Bacteria 1MZ3N@1224,2WX5S@28221,42TST@68525,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) OINAGBCE_01775 631362.Thi970DRAFT_00883 1.8e-17 95.1 Gammaproteobacteria Bacteria 1NA48@1224,1SCJR@1236,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix domain OINAGBCE_01776 1444712.BN1013_01622 8.7e-136 490.3 Chlamydiae ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 2JFCT@204428,COG1252@1,COG1252@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase OINAGBCE_01777 1306947.ARQD01000001_gene898 1.2e-45 190.3 Bacteria Bacteria COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups OINAGBCE_01778 264201.pc1804 5.9e-14 84.0 Chlamydiae ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2JGH9@204428,COG0071@1,COG0071@2 NA|NA|NA O Hsp20/alpha crystallin family OINAGBCE_01779 1437425.CSEC_2349 5.6e-79 301.2 Chlamydiae Bacteria 2JFI9@204428,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase OINAGBCE_01780 765952.PUV_24660 3.3e-43 181.0 Chlamydiae dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 2JG60@204428,COG1734@1,COG1734@2 NA|NA|NA T Prokaryotic dksA/traR C4-type zinc finger OINAGBCE_01781 1444712.BN1013_00503 1e-28 133.3 Chlamydiae lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2JG71@204428,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins OINAGBCE_01782 1444711.CCJF01000005_gene146 2.1e-40 172.6 Chlamydiae Bacteria 2B2S9@1,2JG87@204428,31VCJ@2 NA|NA|NA OINAGBCE_01783 716544.wcw_1747 2.3e-64 253.1 Chlamydiae cinA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019159,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2JFK1@204428,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Probable molybdopterin binding domain OINAGBCE_01787 1444711.CCJF01000004_gene2425 1e-08 67.4 Chlamydiae Bacteria 2JG31@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01789 91604.ID47_04965 1.7e-132 479.2 Rickettsiales fic Bacteria 1MV69@1224,2TT3J@28211,47FF1@766,COG3177@1,COG3177@2 NA|NA|NA S Domain of unknown function (DUF4172) OINAGBCE_01790 331113.SNE_A22750 1.1e-28 134.4 Bacteria Bacteria COG3774@1,COG3774@2 NA|NA|NA M pathogenesis OINAGBCE_01791 331113.SNE_A22750 1.1e-36 161.0 Bacteria Bacteria COG3774@1,COG3774@2 NA|NA|NA M pathogenesis OINAGBCE_01792 331113.SNE_A22750 1.4e-33 150.6 Bacteria Bacteria COG3774@1,COG3774@2 NA|NA|NA M pathogenesis OINAGBCE_01793 1444711.CCJF01000005_gene1127 3.5e-213 748.0 Chlamydiae msbA ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2JFRB@204428,COG1132@1,COG1132@2 NA|NA|NA V Lipid A export ATP-binding permease protein OINAGBCE_01794 331113.SNE_A10660 6e-51 207.6 Chlamydiae prsT ko:K07100 ko00000 Bacteria 2JG9P@204428,COG1926@1,COG1926@2 NA|NA|NA S Phosphoribosyl transferase domain OINAGBCE_01796 479434.Sthe_0831 3e-60 238.4 Bacteria GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K07100 ko00000 Bacteria COG1073@1,COG1073@2 NA|NA|NA S thiolester hydrolase activity OINAGBCE_01797 760142.Hipma_0191 9.7e-31 140.2 Deltaproteobacteria Bacteria 1N1KB@1224,2WS0K@28221,42VBZ@68525,COG3963@1,COG3963@2 NA|NA|NA I Phospholipid N-methyltransferase OINAGBCE_01799 1444711.CCJF01000005_gene1178 5.1e-59 235.0 Chlamydiae acd 3.5.99.7,4.4.1.15 ko:K01505,ko:K05396 ko00270,map00270 R00997,R01874 RC00382,RC00419 ko00000,ko00001,ko01000 Bacteria 2JG5N@204428,COG2515@1,COG2515@2 NA|NA|NA E 1-aminocyclopropane-1-carboxylate deaminase OINAGBCE_01802 765952.PUV_00900 4.9e-67 262.3 Chlamydiae recD GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JH7D@204428,COG0507@1,COG0507@2 NA|NA|NA L exodeoxyribonuclease V alpha OINAGBCE_01803 1444712.BN1013_00408 5.8e-120 439.1 Chlamydiae recB GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5,3.6.4.12 ko:K03406,ko:K03582,ko:K16898 ko02020,ko02030,ko03440,map02020,map02030,map03440 ko00000,ko00001,ko01000,ko02035,ko03400 Bacteria 2JFIP@204428,COG1074@1,COG1074@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA OINAGBCE_01804 1444711.CCJF01000005_gene386 8.4e-57 229.2 Chlamydiae recC GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 ko:K03583 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFNT@204428,COG1330@1,COG1330@2 NA|NA|NA L Exodeoxyribonuclease V, gamma subunit OINAGBCE_01805 765952.PUV_03710 4.3e-119 435.3 Chlamydiae aas 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 Bacteria 2JFDV@204428,COG0204@1,COG0204@2,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily OINAGBCE_01806 1123242.JH636435_gene793 8.2e-132 477.2 Planctomycetes phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 2IZKY@203682,COG0415@1,COG0415@2 NA|NA|NA L FAD binding domain of DNA photolyase OINAGBCE_01807 671143.DAMO_2354 7.5e-67 260.8 unclassified Bacteria ko:K07071 ko00000 Bacteria 2NPHC@2323,COG1090@1,COG1090@2 NA|NA|NA S Domain of unknown function (DUF1731) OINAGBCE_01810 1306947.ARQD01000001_gene661 1.9e-42 179.5 Bacteria ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria COG0834@1,COG0834@2 NA|NA|NA ET amino acid transport OINAGBCE_01811 1306947.ARQD01000001_gene662 2.5e-16 92.0 unclassified Bacteria argR GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0032991,GO:0032993,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140110,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 2NRVI@2323,COG1438@1,COG1438@2 NA|NA|NA K Arginine repressor, DNA binding domain OINAGBCE_01813 244581.IM40_01310 2.2e-63 250.0 Rickettsiales ko:K03305 ko00000 2.A.17 Bacteria 1MW6W@1224,2U15C@28211,47FJX@766,COG3104@1,COG3104@2 NA|NA|NA E POT family OINAGBCE_01814 1122137.AQXF01000002_gene315 8.3e-100 370.9 Alphaproteobacteria pepA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUF9@1224,2TQU9@28211,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides OINAGBCE_01815 1444711.CCJF01000004_gene2078 5.9e-142 510.8 Bacteria ko:K07126 ko00000 Bacteria COG4782@1,COG4782@2 NA|NA|NA P Protein conserved in bacteria OINAGBCE_01817 765952.PUV_01230 1.6e-67 263.5 Chlamydiae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 2JGQK@204428,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J NusB family OINAGBCE_01818 765952.PUV_00570 4.3e-81 308.1 Chlamydiae cyoE GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 iSFxv_1172.SFxv_0410,iYO844.BSU12080 Bacteria 2JFWP@204428,COG0109@1,COG0109@2 NA|NA|NA H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group OINAGBCE_01819 69014.TK2220 2.1e-60 240.0 Thermococci ko:K07133 ko00000 Archaea 243NX@183968,2XXQC@28890,COG1373@1,arCOG03167@2157 NA|NA|NA S Domain of unknown function (DUF4143) OINAGBCE_01820 1444711.CCJF01000005_gene1428 2e-241 841.6 Chlamydiae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 2JFKT@204428,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP OINAGBCE_01821 1444711.CCJF01000005_gene1664 1.4e-87 329.3 Chlamydiae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264,2.1.1.72 ko:K00571,ko:K06969,ko:K12297 R07234 RC00003 ko00000,ko01000,ko02048,ko03009 Bacteria 2JFKR@204428,COG1092@1,COG1092@2 NA|NA|NA J S-adenosylmethionine-dependent methyltransferase OINAGBCE_01822 1255043.TVNIR_0910 1.7e-08 65.5 Bacteria Bacteria COG0399@1,COG0399@2 NA|NA|NA E UDP-4-amino-4-deoxy-L-arabinose aminotransferase OINAGBCE_01823 331113.SNE_A00660 1.1e-123 449.5 Bacteria Bacteria 28M46@1,2ZAI5@2 NA|NA|NA OINAGBCE_01824 331113.SNE_A00670 8.7e-296 1022.7 Bacteria ko:K07445 ko00000 Bacteria COG1743@1,COG1743@2 NA|NA|NA L DNA methylAse OINAGBCE_01825 765952.PUV_07020 1.1e-287 995.7 Chlamydiae hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 2JFK4@204428,COG3808@1,COG3808@2 NA|NA|NA C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force OINAGBCE_01826 3067.XP_002957286.1 3.1e-16 93.6 Chlorophyta Viridiplantae 28J60@1,2QRI3@2759,34JYH@3041,37KCF@33090 NA|NA|NA S Domain of unknown function (DUF1995) OINAGBCE_01827 1444712.BN1013_02314 7.7e-63 246.9 Chlamydiae MA20_24580 Bacteria 2JG3R@204428,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase OINAGBCE_01828 264201.pc0441 8.3e-108 397.5 Chlamydiae CP_0235 Bacteria 28K7C@1,2JFID@204428,2Z9VH@2 NA|NA|NA S Uncharacterised protein family (UPF0158) OINAGBCE_01829 765952.PUV_23330 4.8e-34 151.4 Chlamydiae atpE ko:K02121 ko00190,ko01100,map00190,map01100 M00159 ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 Bacteria 2JG7T@204428,COG1390@1,COG1390@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane OINAGBCE_01830 716544.wcw_0604 3.8e-49 201.8 Chlamydiae CP_0687 Bacteria 28PGQ@1,2JFYT@204428,2ZC7E@2 NA|NA|NA S Protein of unknown function (DUF2764) OINAGBCE_01831 1444711.CCJF01000004_gene2284 2.7e-252 877.9 Chlamydiae atpA 3.6.3.14,3.6.3.15 ko:K02117 ko00190,ko01100,map00190,map01100 M00159 ko00000,ko00001,ko00002,ko01000 3.A.2.2,3.A.2.3 Bacteria 2JFIJ@204428,COG1155@1,COG1155@2 NA|NA|NA F Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit OINAGBCE_01832 1444712.BN1013_00829 2.2e-198 698.4 Chlamydiae atpB ko:K02118 ko00190,ko01100,map00190,map01100 M00159 ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 Bacteria 2JFMM@204428,COG1156@1,COG1156@2 NA|NA|NA F Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit OINAGBCE_01833 1444712.BN1013_00830 6.7e-52 210.7 Chlamydiae atpD ko:K02118,ko:K02120 ko00190,ko01100,map00190,map01100 M00159 ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 Bacteria 2JG3P@204428,COG1394@1,COG1394@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane OINAGBCE_01834 765952.PUV_23280 3.6e-141 508.8 Chlamydiae atpI ko:K02123 ko00190,ko01100,map00190,map01100 M00159 ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 Bacteria 2JFCG@204428,COG1269@1,COG1269@2 NA|NA|NA C ATP synthase, subunit I OINAGBCE_01835 1444711.CCJF01000004_gene2288 3.4e-39 167.9 Chlamydiae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110,ko:K02124 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157,M00159 ko00000,ko00001,ko00002,ko00194 3.A.2.1,3.A.2.2,3.A.2.3 Bacteria 2JG1V@204428,COG0636@1,COG0636@2 NA|NA|NA C ATP synthase, subunit OINAGBCE_01837 596151.DesfrDRAFT_0594 4.2e-153 548.5 Desulfovibrionales Bacteria 1R829@1224,2M85I@213115,2WINQ@28221,42MS5@68525,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease OINAGBCE_01838 1121904.ARBP01000003_gene6362 8.8e-15 87.0 Bacteria Bacteria 29C7G@1,2ZZ61@2 NA|NA|NA OINAGBCE_01839 765952.PUV_25570 1.2e-110 406.8 Chlamydiae Bacteria 2JGPR@204428,COG0457@1,COG0457@2,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 OINAGBCE_01841 716544.wcw_1781 4.2e-107 395.2 Chlamydiae Bacteria 2JFR5@204428,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase OINAGBCE_01842 716544.wcw_1782 1.9e-101 375.6 Chlamydiae sdhB GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFQ7@204428,COG0479@1,COG0479@2 NA|NA|NA C succinate dehydrogenase OINAGBCE_01843 1444711.CCJF01000005_gene205 2.3e-257 894.8 Chlamydiae sdhA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05640 Bacteria 2JFSU@204428,COG1053@1,COG1053@2 NA|NA|NA C succinate dehydrogenase OINAGBCE_01844 1444711.CCJF01000005_gene206 6.1e-65 254.6 Chlamydiae sdhC ko:K00241,ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 iYO844.BSU28450 Bacteria 2JFCP@204428,COG2009@1,COG2009@2 NA|NA|NA C succinate dehydrogenase OINAGBCE_01847 765952.PUV_11490 1.5e-87 329.7 Chlamydiae czcD Bacteria 2JFUK@204428,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family OINAGBCE_01848 716544.wcw_0109 1.3e-60 240.0 Chlamydiae tatD GO:0000175,GO:0000302,GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009056,GO:0009057,GO:0009636,GO:0009987,GO:0010035,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046700,GO:0046872,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901700 ko:K03424 ko00000,ko01000 Bacteria 2JFVX@204428,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase OINAGBCE_01849 765952.PUV_27380 1.4e-142 513.8 Chlamydiae dsbD 1.8.1.8 ko:K04084,ko:K06888 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 2JFKV@204428,COG4232@1,COG4232@2,COG4233@1,COG4233@2 NA|NA|NA CO Thiol disulfide interchange protein OINAGBCE_01850 264201.pc1847 1.6e-57 229.6 Chlamydiae exbB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0023052,GO:0031224,GO:0031226,GO:0031647,GO:0031992,GO:0032991,GO:0033036,GO:0042802,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0060089,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:0098797 ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 iSBO_1134.SBO_3000,iSbBS512_1146.SbBS512_E3434 Bacteria 2JFXS@204428,COG0811@1,COG0811@2 NA|NA|NA U MotA TolQ ExbB proton channel family protein OINAGBCE_01851 1444711.CCJF01000005_gene211 6.3e-30 137.1 Chlamydiae exbD ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2JGAW@204428,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR OINAGBCE_01852 1444711.CCJF01000005_gene212 4.7e-14 85.9 Chlamydiae ko:K03646,ko:K03832 ko00000,ko02000 2.C.1.1,2.C.1.2 Bacteria 2JGFW@204428,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins OINAGBCE_01854 1444711.CCJF01000005_gene213 1.1e-70 274.2 Chlamydiae tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 2JFJD@204428,COG0823@1,COG0823@2 NA|NA|NA U Involved in the TonB-independent uptake of proteins OINAGBCE_01855 1444712.BN1013_00328 8.8e-61 240.4 Chlamydiae pal ko:K03640 ko00000,ko02000 2.C.1.2 Bacteria 2JG4H@204428,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family OINAGBCE_01856 1444712.BN1013_00329 8.4e-18 97.4 Chlamydiae iap GO:0005575,GO:0005576 3.2.1.17,3.5.1.104,3.5.1.28 ko:K01185,ko:K01448,ko:K01449,ko:K08307,ko:K13735,ko:K14196,ko:K19220,ko:K19223,ko:K21449,ko:K22278 ko01503,ko05100,ko05150,map01503,map05100,map05150 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02000,ko03036 1.B.40.2 CBM50 Bacteria 2JGAD@204428,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif OINAGBCE_01857 1444711.CCJF01000005_gene216 6e-31 140.6 Chlamydiae murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2JG0N@204428,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis OINAGBCE_01858 886293.Sinac_5619 3.5e-63 248.8 Planctomycetes ko:K01066 ko00000,ko01000 Bacteria 2IZAJ@203682,COG0657@1,COG0657@2 NA|NA|NA I Alpha beta hydrolase fold OINAGBCE_01859 255470.cbdbA1156 3.4e-13 80.1 Dehalococcoidia mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 2G9VU@200795,34DGU@301297,COG1193@1,COG1193@2 NA|NA|NA L Smr domain OINAGBCE_01860 1121091.AUMP01000024_gene2978 1.5e-30 141.7 Bacilli alkJ 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1UY91@1239,4HBD1@91061,COG2303@1,COG2303@2 NA|NA|NA E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate OINAGBCE_01863 1444711.CCJF01000005_gene1362 6.1e-121 441.0 Chlamydiae rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 ko:K07478 ko00000 Bacteria 2JFSV@204428,COG2256@1,COG2256@2 NA|NA|NA L MgsA AAA+ ATPase C terminal OINAGBCE_01864 765952.PUV_21530 2.1e-143 515.4 Chlamydiae Bacteria 2JGPQ@204428,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 OINAGBCE_01865 1437425.CSEC_0415 3.4e-54 219.2 Chlamydiae Bacteria 2C73G@1,2JGZQ@204428,33U9P@2 NA|NA|NA OINAGBCE_01867 1444711.CCJF01000005_gene158 2e-64 252.7 Chlamydiae znuA 1.6.5.3 ko:K00341,ko:K02077,ko:K09815 ko00190,ko01100,ko02010,map00190,map01100,map02010 M00144,M00242,M00244 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.D.1 Bacteria 2JG45@204428,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family OINAGBCE_01868 1444712.BN1013_00478 4.8e-73 281.2 Chlamydiae adcC ko:K09817 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 iHN637.CLJU_RS15665,iYO844.BSU02860 Bacteria 2JFY8@204428,COG1121@1,COG1121@2 NA|NA|NA P metal transport system ATP-binding protein OINAGBCE_01869 1444712.BN1013_00479 7.9e-85 320.5 Chlamydiae znuB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K02075,ko:K09816,ko:K19976 ko02010,map02010 M00242,M00244,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2JFS1@204428,COG1108@1,COG1108@2 NA|NA|NA P metal transport system membrane protein OINAGBCE_01871 2074.JNYD01000012_gene195 1.9e-21 111.3 Pseudonocardiales MA20_17095 Bacteria 2H2SY@201174,4DXGA@85010,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase OINAGBCE_01872 933262.AXAM01000022_gene3247 9.1e-129 467.2 Deltaproteobacteria ko:K06921 ko00000 Bacteria 1MWJX@1224,2WPWZ@28221,42R4K@68525,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea OINAGBCE_01873 264201.pc1810 4.5e-192 677.6 Chlamydiae dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2JFQP@204428,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication OINAGBCE_01874 331635.G5S_0073 1.3e-46 193.7 Chlamydiae plsX 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 ko:K03621,ko:K21576,ko:K21577 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JFZ7@204428,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA OINAGBCE_01875 1444712.BN1013_00055 1.3e-28 132.9 Chlamydiae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2JGEY@204428,COG1399@1,COG1399@2 NA|NA|NA S metal-binding, possibly nucleic acid-binding protein OINAGBCE_01876 1444712.BN1013_00571 8.9e-98 364.0 Chlamydiae tyrP_1 ko:K03834 ko00000,ko02000 2.A.42.1.1 Bacteria 2JFWX@204428,COG0814@1,COG0814@2 NA|NA|NA E transport protein OINAGBCE_01877 1444711.CCJF01000005_gene979 7.7e-219 766.5 Chlamydiae rng 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2JFU4@204428,COG1530@1,COG1530@2 NA|NA|NA J ribonuclease G OINAGBCE_01878 1444711.CCJF01000005_gene978 3.9e-91 341.7 Chlamydiae plsB 2.3.1.15 ko:K00630,ko:K00631,ko:K14598 ko00561,ko00564,ko00906,ko01100,ko01110,map00561,map00564,map00906,map01100,map01110 M00089 R00851,R07545,R07547,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JFD3@204428,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase OINAGBCE_01880 1521187.JPIM01000058_gene2550 9.6e-23 112.8 Chloroflexia ko:K07075 ko00000 Bacteria 2G76P@200795,377KK@32061,COG1669@1,COG1669@2 NA|NA|NA L Nucleotidyltransferase domain OINAGBCE_01881 102232.GLO73106DRAFT_00039500 9.4e-21 106.3 Cyanobacteria Bacteria 1G7XA@1117,COG2361@1,COG2361@2 NA|NA|NA S COGs COG2361 conserved OINAGBCE_01882 765952.PUV_26150 7.9e-216 756.5 Chlamydiae proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2JFHZ@204428,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) OINAGBCE_01883 1444711.CCJF01000005_gene966 8.5e-91 340.1 Chlamydiae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 2JFMK@204428,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional Regulatory Protein OINAGBCE_01884 716544.wcw_0241 7e-64 251.5 Chlamydiae hemG 1.14.19.9,1.3.3.15,1.3.3.4 ko:K00231,ko:K14266 ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130 M00121,M00789,M00790 R03222,R04178,R09570 RC00885,RC00949 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS09325 Bacteria 2JFUM@204428,COG1232@1,COG1232@2 NA|NA|NA H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX OINAGBCE_01887 46234.ANA_C20213 4.3e-26 125.6 Cyanobacteria Bacteria 1G3F2@1117,COG0642@1,COG0784@1,COG0784@2,COG2205@2,COG3447@1,COG3447@2 NA|NA|NA T PhoQ Sensor OINAGBCE_01888 813.O172_04140 1.8e-118 433.0 Bacteria hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 Bacteria COG0635@1,COG0635@2 NA|NA|NA H coproporphyrinogen oxidase activity OINAGBCE_01889 1444712.BN1013_00175 6.1e-92 344.4 Chlamydiae hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0016 Bacteria 2JFYX@204428,COG0407@1,COG0407@2 NA|NA|NA H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III OINAGBCE_01890 1444711.CCJF01000004_gene1876 1.7e-266 925.2 Chlamydiae tkt GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030312,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Bacteria 2JFFT@204428,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate OINAGBCE_01894 765952.PUV_03780 1.1e-16 93.6 Chlamydiae yacP ko:K06962 ko00000 Bacteria 2JGDZ@204428,COG3688@1,COG3688@2 NA|NA|NA S YacP-like NYN domain OINAGBCE_01895 1437425.CSEC_1684 5.2e-27 127.9 Chlamydiae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_1875 Bacteria 2JG0G@204428,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions OINAGBCE_01896 1444711.CCJF01000005_gene518 1.2e-201 709.9 Chlamydiae greA Bacteria 2JFR7@204428,COG0782@1,COG0782@2,COG1747@1,COG1747@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides OINAGBCE_01898 1444711.CCJF01000005_gene557 5.5e-101 374.4 Chlamydiae moxR ko:K03924 ko00000,ko01000 Bacteria 2JGN0@204428,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) OINAGBCE_01899 946077.W5A_01295 1.8e-63 249.6 Flavobacteriia GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 1HX4X@117743,4NE2N@976,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) OINAGBCE_01901 1437425.CSEC_1729 1.3e-09 70.9 Chlamydiae Bacteria 2E8V4@1,2JGE9@204428,3335H@2 NA|NA|NA OINAGBCE_01902 264201.pc1892 6.9e-10 71.2 Chlamydiae ppdC ko:K02458,ko:K02671,ko:K02681,ko:K10927 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15 Bacteria 2JGU0@204428,COG4967@1,COG4967@2 NA|NA|NA NU type IV pilus modification protein PilV OINAGBCE_01905 765952.PUV_25640 1.5e-20 105.9 Chlamydiae ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2JGF1@204428,COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein G OINAGBCE_01906 765952.PUV_25650 1.3e-80 307.0 Chlamydiae gspF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2JFUD@204428,COG1459@1,COG1459@2 NA|NA|NA U General secretion pathway protein F OINAGBCE_01907 765952.PUV_25660 2.2e-174 619.0 Chlamydiae gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2JFKZ@204428,COG2804@1,COG2804@2 NA|NA|NA NU General secretion pathway protein E OINAGBCE_01908 1444711.CCJF01000005_gene536 7.4e-171 607.8 Chlamydiae gspD ko:K02453,ko:K02666 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2JFRY@204428,COG1450@1,COG1450@2 NA|NA|NA NU general secretion pathway protein D OINAGBCE_01909 765952.PUV_25680 4.8e-66 258.8 Chlamydiae CP_1057 Bacteria 28KZP@1,2JFFR@204428,2ZAEV@2 NA|NA|NA OINAGBCE_01910 1437425.CSEC_1720 4.3e-09 67.8 Chlamydiae Bacteria 2E46T@1,2JGEM@204428,32Z2R@2 NA|NA|NA OINAGBCE_01911 765952.PUV_25420 7.6e-93 347.4 Chlamydiae mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2JFTR@204428,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase OINAGBCE_01912 765952.PUV_27030 4.6e-81 307.8 Chlamydiae waaE ko:K12984 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 Bacteria 2JFTY@204428,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 OINAGBCE_01915 264201.pc1876 1.3e-43 183.0 Chlamydiae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2JFYW@204428,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another OINAGBCE_01916 765952.PUV_00370 1.8e-60 239.2 Chlamydiae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2JG3X@204428,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP OINAGBCE_01917 1444711.CCJF01000005_gene252 5.2e-92 344.4 Chlamydiae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2JFNI@204428,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome OINAGBCE_01918 716544.wcw_1933 1.6e-98 365.9 Chlamydiae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JFQ4@204428,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family OINAGBCE_01920 1444711.CCJF01000005_gene255 6.5e-233 814.3 Chlamydiae pbp2 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2JFNP@204428,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein OINAGBCE_01922 521098.Aaci_2495 9.4e-101 374.0 Bacilli Bacteria 1TP6X@1239,4IQRT@91061,COG2271@1,COG2271@2 NA|NA|NA G Major facilitator superfamily OINAGBCE_01923 716544.wcw_0085 2.2e-220 771.5 Chlamydiae sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 ko:K07033,ko:K09014 ko00000 iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 Bacteria 2JFJM@204428,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) OINAGBCE_01924 1444711.CCJF01000005_gene631 6.9e-96 357.1 Chlamydiae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 2JFF7@204428,COG0396@1,COG0396@2 NA|NA|NA O ABC transporter OINAGBCE_01925 1444711.CCJF01000005_gene632 4.5e-87 328.6 Chlamydiae sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K07033,ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2JFQN@204428,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) OINAGBCE_01926 1444711.CCJF01000005_gene633 8.9e-146 523.5 Chlamydiae sufS 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 2JFTA@204428,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine OINAGBCE_01927 1437425.CSEC_1752 1.5e-62 246.5 Chlamydiae sctT ko:K02421,ko:K03228 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2JFXE@204428,COG4791@1,COG4791@2 NA|NA|NA U type III secretion inner membrane protein SctT OINAGBCE_01928 765952.PUV_22770 2.4e-32 146.4 Chlamydiae Bacteria 29XK7@1,2JG3A@204428,30JBA@2 NA|NA|NA OINAGBCE_01929 716544.wcw_0092 1.7e-28 131.7 Chlamydiae sctS ko:K03227 ko03070,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 Bacteria 2JGCB@204428,COG4794@1,COG4794@2 NA|NA|NA U type III secretion inner membrane protein SctS OINAGBCE_01930 1444711.CCJF01000005_gene645 9.4e-84 317.0 Chlamydiae ssaR ko:K03226,ko:K22507 ko03070,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 Bacteria 2JHI6@204428,COG4790@1,COG4790@2 NA|NA|NA U Type III secretion inner membrane protein SctR OINAGBCE_01931 765952.PUV_01450 3.2e-57 228.4 Chlamydiae fliH ko:K02411,ko:K03223 ko02040,ko03070,map02040,map03070 M00332,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 2JG0V@204428,COG1317@1,COG1317@2 NA|NA|NA NU Type III OINAGBCE_01932 264201.pc0204 3.1e-28 132.5 Chlamydiae CP_1044 Bacteria 2C2FJ@1,2JG5S@204428,32RAD@2 NA|NA|NA OINAGBCE_01933 765952.PUV_01430 6.5e-89 334.3 Chlamydiae sctJ ko:K03222 ko03070,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 Bacteria 2JFMR@204428,COG4669@1,COG4669@2 NA|NA|NA U Type III OINAGBCE_01934 1444712.BN1013_00316 2.6e-42 179.5 Chlamydiae ko:K21010 ko02025,map02025 ko00000,ko00001 Bacteria 2JFKJ@204428,COG1413@1,COG1413@2 NA|NA|NA C lyase activity OINAGBCE_01935 765952.PUV_26050 5.6e-111 407.5 Chlamydiae lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2JFWH@204428,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives OINAGBCE_01936 1444711.CCJF01000005_gene582 1.6e-151 542.7 Chlamydiae lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JFIX@204428,COG1249@1,COG1249@2 NA|NA|NA C The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) OINAGBCE_01941 765952.PUV_12320 1.2e-122 446.8 Chlamydiae lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045271,GO:0046390,GO:0046483,GO:0046496,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0070469,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iE2348C_1286.E2348C_4372,iJN746.PP_4187 Bacteria 2JFG6@204428,COG1249@1,COG1249@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes OINAGBCE_01942 1444711.CCJF01000005_gene1219 4e-110 404.8 Chlamydiae sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 Bacteria 2JFPZ@204428,COG0508@1,COG0508@2 NA|NA|NA C 2-oxoglutarate dehydrogenase OINAGBCE_01943 1444711.CCJF01000005_gene1218 6e-229 800.8 Chlamydiae sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 2JFWQ@204428,COG0567@1,COG0567@2 NA|NA|NA C dehydrogenase e1 component OINAGBCE_01944 716544.wcw_0984 4e-39 167.9 Chlamydiae Bacteria 2DMAA@1,2JG6W@204428,32BTP@2 NA|NA|NA OINAGBCE_01945 716544.wcw_0983 1.3e-103 383.3 Chlamydiae hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 Bacteria 2JFTP@204428,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound OINAGBCE_01949 754476.Q7A_2206 2.3e-48 199.9 Thiotrichales gltP ko:K03309 ko00000 2.A.23 Bacteria 1MU0Q@1224,1RMEN@1236,4604B@72273,COG1301@1,COG1301@2 NA|NA|NA C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family OINAGBCE_01950 86106.I862_00775 3.3e-114 418.7 Rickettsiales potE GO:0000064,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0006873,GO:0006885,GO:0006950,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008519,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015171,GO:0015174,GO:0015179,GO:0015181,GO:0015189,GO:0015203,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015297,GO:0015298,GO:0015318,GO:0015489,GO:0015490,GO:0015491,GO:0015496,GO:0015672,GO:0015695,GO:0015696,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015822,GO:0015839,GO:0015846,GO:0015847,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0033554,GO:0034220,GO:0042221,GO:0042493,GO:0042592,GO:0042802,GO:0043872,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0051716,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071214,GO:0071467,GO:0071468,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:0104004,GO:1902022,GO:1902047,GO:1902475,GO:1902600,GO:1903352,GO:1903401,GO:1903825,GO:1903826,GO:1905039,GO:1990451,GO:1990822 ko:K03294,ko:K03756,ko:K03757,ko:K03759 ko00000,ko02000 2.A.3.2 iAF1260.b0692,iAF1260.b4132,iAPECO1_1312.APECO1_2321,iB21_1397.B21_00640,iB21_1397.B21_03965,iBWG_1329.BWG_0551,iBWG_1329.BWG_3846,iE2348C_1286.E2348C_0581,iE2348C_1286.E2348C_4459,iEC042_1314.EC042_4498,iEC55989_1330.EC55989_4625,iECABU_c1320.ECABU_c07430,iECABU_c1320.ECABU_c46860,iECBD_1354.ECBD_2969,iECBD_1354.ECBD_3898,iECB_1328.ECB_00648,iECB_1328.ECB_04003,iECDH10B_1368.ECDH10B_0758,iECDH10B_1368.ECDH10B_4325,iECDH1ME8569_1439.ECDH1ME8569_0650,iECD_1391.ECD_00648,iECD_1391.ECD_04003,iECH74115_1262.ECH74115_5648,iECIAI1_1343.ECIAI1_0668,iECIAI1_1343.ECIAI1_4365,iECNA114_1301.ECNA114_0628,iECNA114_1301.ECNA114_4318,iECO103_1326.ECO103_0686,iECO103_1326.ECO103_4884,iECO26_1355.ECO26_0754,iECO26_1355.ECO26_5227,iECO26_1355.ECO26_5244,iECOK1_1307.ECOK1_4644,iECP_1309.ECP_0710,iECP_1309.ECP_4376,iECS88_1305.ECS88_4636,iECSE_1348.ECSE_0751,iECSE_1348.ECSE_4432,iECSF_1327.ECSF_0627,iECSF_1327.ECSF_4021,iECSP_1301.ECSP_5232,iECUMN_1333.ECUMN_4666,iECW_1372.ECW_m0742,iECW_1372.ECW_m4493,iECs_1301.ECs5114,iEKO11_1354.EKO11_3188,iEKO11_1354.EKO11_4186,iETEC_1333.ETEC_0708,iETEC_1333.ETEC_4443,iEcDH1_1363.EcDH1_2945,iEcE24377_1341.EcE24377A_4687,iEcHS_1320.EcHS_A4373,iEcSMS35_1347.EcSMS35_4601,iEcolC_1368.EcolC_2964,iEcolC_1368.EcolC_3895,iG2583_1286.G2583_4959,iJO1366.b0692,iJO1366.b4132,iJR904.b0692,iJR904.b4132,iLF82_1304.LF82_0255,iNRG857_1313.NRG857_20730,iSSON_1240.SSON_0643,iUMN146_1321.UM146_20900,iUMNK88_1353.UMNK88_4999,iUMNK88_1353.UMNK88_728,iUTI89_1310.UTI89_C4729,iWFL_1372.ECW_m0742,iWFL_1372.ECW_m4493,iY75_1357.Y75_RS03590,iY75_1357.Y75_RS21520,ic_1306.c0776,ic_1306.c5141 Bacteria 1MUA2@1224,2TSV9@28211,47EYE@766,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease OINAGBCE_01952 1444712.BN1013_02326 2.7e-59 235.3 Chlamydiae adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 Bacteria 2JG11@204428,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism OINAGBCE_01956 227377.CBU_0819 1.8e-40 172.9 Legionellales 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1JF0B@118969,1RJVR@1224,1RXVB@1236,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain OINAGBCE_01958 351016.RAZWK3B_09896 1.7e-81 309.7 Alphaproteobacteria 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 Bacteria 1RKZQ@1224,2U13U@28211,COG3473@1,COG3473@2 NA|NA|NA Q Maleate cis-trans isomerase OINAGBCE_01959 251229.Chro_1508 5e-52 210.7 Cyanobacteria MA20_02285 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1GQF0@1117,COG0454@1,COG0454@2 NA|NA|NA K PFAM Acetyltransferase (GNAT) family OINAGBCE_01960 1144888.CM001467_gene468 2.8e-75 289.3 Rickettsiales bcr2 ko:K07552 ko00000,ko02000 2.A.1.2 Bacteria 1MW19@1224,2TRQD@28211,47F4F@766,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily OINAGBCE_01961 1444711.CCJF01000004_gene2074 1.8e-80 305.8 Chlamydiae Bacteria 2JG7F@204428,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain OINAGBCE_01964 765952.PUV_01170 0.0 1308.9 Chlamydiae secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2JFI8@204428,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane OINAGBCE_01965 404589.Anae109_0107 1.9e-32 146.7 Bacteria uvrD Bacteria COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily OINAGBCE_01967 945713.IALB_0222 6e-32 146.0 Bacteria yjcH ko:K07214 ko00000 Bacteria COG2382@1,COG2382@2 NA|NA|NA P enterobactin catabolic process OINAGBCE_01969 264201.pc0071 3.5e-274 951.0 Chlamydiae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2JFEK@204428,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone OINAGBCE_01970 1444712.BN1013_01270 1.9e-59 236.5 Bacteria dprA ko:K04096 ko00000 Bacteria COG0758@1,COG0758@2 NA|NA|NA LU DNA mediated transformation OINAGBCE_01973 264201.pc0077 1.5e-45 189.9 Chlamydiae parB ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2JG0S@204428,COG1475@1,COG1475@2 NA|NA|NA K Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity) OINAGBCE_01974 765952.PUV_07970 8.9e-52 211.1 Chlamydiae batA ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2JG0W@204428,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain OINAGBCE_01975 716544.wcw_0326 1.2e-26 127.5 Chlamydiae ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2JFYI@204428,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain OINAGBCE_01977 1121899.Q764_05805 2.5e-09 71.2 Flavobacterium Bacteria 1HY3Z@117743,2NU61@237,4NG09@976,COG3291@1,COG3291@2 NA|NA|NA O Fungalysin metallopeptidase (M36) OINAGBCE_01978 765952.PUV_08000 3.2e-61 243.0 Chlamydiae Bacteria 2JFWD@204428,COG0457@1,COG0457@2 NA|NA|NA S Oxygen tolerance OINAGBCE_01979 716544.wcw_0329 1.4e-32 146.7 Chlamydiae Bacteria 2JGC5@204428,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_01980 1444711.CCJF01000005_gene285 2e-66 259.6 Chlamydiae Bacteria 28PQ7@1,2JFZ6@204428,2ZCCC@2 NA|NA|NA OINAGBCE_01981 1444711.CCJF01000005_gene288 2.6e-71 275.4 Chlamydiae CP_0141 ko:K07099 ko00000 Bacteria 2JFIA@204428,COG1768@1,COG1768@2 NA|NA|NA S Calcineurin-like phosphoesterase OINAGBCE_01982 264201.pc0109 2.8e-140 505.4 Chlamydiae glgC 2.7.7.27,3.2.1.68 ko:K00975,ko:K01214 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R09995,R11261 RC00002 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 iJN678.agp,iSbBS512_1146.agp Bacteria 2JGPA@204428,COG0448@1,COG0448@2 NA|NA|NA H glucose-1-phosphate adenylyltransferase OINAGBCE_01983 1444712.BN1013_00431 9.9e-73 280.8 Chlamydiae ko:K08223 ko00000,ko02000 2.A.1.35 Bacteria 2JFUR@204428,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily OINAGBCE_01984 765952.PUV_25720 2e-09 71.6 Chlamydiae Bacteria 2JGQS@204428,COG2849@1,COG2849@2 NA|NA|NA S MORN repeat variant OINAGBCE_01985 9593.ENSGGOP00000001171 1.2e-10 74.3 Hominidae FBXL4 GO:0000151,GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016567,GO:0016604,GO:0016607,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031981,GO:0032446,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0051603,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 ko:K10270 ko00000,ko03029,ko04121 Mammalia 35A9H@314146,38EAP@33154,3BDEX@33208,3CRVG@33213,3JBKV@40674,47Z10@7711,490RZ@7742,4MET6@9443,4MTSY@9604,KOG1947@1,KOG1947@2759 NA|NA|NA S Leucine-rich repeat - CC (cysteine-containing) subfamily OINAGBCE_01988 485913.Krac_11202 5.3e-89 335.1 Bacteria ko:K11159 ko00000 Bacteria COG3670@1,COG3670@2 NA|NA|NA Q oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen OINAGBCE_01992 1444711.CCJF01000005_gene1661 4.5e-12 77.8 Chlamydiae MA20_36130 Bacteria 2DMHT@1,2JHBR@204428,32RN3@2 NA|NA|NA S PEGA domain OINAGBCE_01993 673862.BABL1_57 1.7e-31 142.5 Deltaproteobacteria ytfC 5.2.1.8 ko:K01802,ko:K03772 ko00000,ko01000,ko03110 Bacteria 1RDA1@1224,2WMRQ@28221,42QU4@68525,COG0545@1,COG0545@2 NA|NA|NA M peptidylprolyl isomerase, FKBP-type OINAGBCE_01995 264201.pc0818 1.1e-106 393.3 Chlamydiae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2JFFE@204428,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction OINAGBCE_01996 1150474.JQJI01000004_gene428 5.3e-22 110.5 Thermotogae ko:K07171 ko00000,ko01000,ko02048 Bacteria 2GE78@200918,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module OINAGBCE_01997 716544.wcw_1208 2.5e-07 61.2 Bacteria Bacteria 2EH4M@1,33AWJ@2 NA|NA|NA OINAGBCE_01998 215803.DB30_4046 2.5e-111 409.5 Myxococcales 2.7.9.1,2.7.9.2 ko:K01006,ko:K01007 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 1P35R@1224,2WR5R@28221,2YXK9@29,42UE9@68525,COG0574@1,COG0574@2 NA|NA|NA G Pyruvate phosphate dikinase, PEP/pyruvate binding domain OINAGBCE_02001 135651.CBN07770 1.8e-08 67.8 Chromadorea Nematoda 1KW1A@119089,38FJY@33154,3BDCN@33208,3CY84@33213,40DMX@6231,KOG0590@1,KOG0590@2759 NA|NA|NA D Belongs to the protein kinase superfamily OINAGBCE_02002 765952.PUV_16330 7.2e-47 194.1 Chlamydiae pgl 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2JFZ0@204428,COG0363@1,COG0363@2 NA|NA|NA G 6-phosphogluconolactonase OINAGBCE_02003 765952.PUV_16320 5.6e-59 235.0 Chlamydiae opcA Bacteria 2JG6P@204428,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit OINAGBCE_02004 1444711.CCJF01000005_gene1402 1.9e-217 761.9 Chlamydiae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2JFEN@204428,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone OINAGBCE_02006 675815.VOA_000164 5.7e-07 62.4 Gammaproteobacteria Bacteria 1NTF4@1224,1SKNK@1236,2F0BX@1,33TF3@2 NA|NA|NA OINAGBCE_02007 1229172.JQFA01000002_gene4997 4e-16 93.2 Oscillatoriales rihA GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1G231@1117,1H7HE@1150,COG1957@1,COG1957@2 NA|NA|NA F PFAM Inosine-uridine preferring nucleoside hydrolase OINAGBCE_02008 716544.wcw_0687 4.2e-276 957.2 Chlamydiae pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2JFFK@204428,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction OINAGBCE_02009 1444711.CCJF01000005_gene1780 5.7e-37 159.8 Chlamydiae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG4W@204428,COG0184@1,COG0184@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA OINAGBCE_02010 716544.wcw_0691 1.7e-10 71.6 Chlamydiae CP_0851 Bacteria 2JGFE@204428,COG0590@1,COG0590@2 NA|NA|NA FJ tRNA wobble adenosine to inosine editing OINAGBCE_02011 1444711.CCJF01000005_gene1777 1.7e-53 215.7 Chlamydiae tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K04075,ko:K11991 ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko01002,ko01011,ko03016 Bacteria 2JFZJ@204428,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) OINAGBCE_02012 765952.PUV_10470 1.4e-26 126.3 Chlamydiae Bacteria 2F34V@1,2JH2G@204428,33VZJ@2 NA|NA|NA OINAGBCE_02013 716544.wcw_0693 1.6e-24 120.2 Chlamydiae Bacteria 2JG8J@204428,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family OINAGBCE_02014 765952.PUV_18830 1.2e-26 125.9 Chlamydiae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG9J@204428,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 OINAGBCE_02015 716544.wcw_0695 1.7e-121 442.6 Chlamydiae prfA ko:K02835 ko00000,ko03012 Bacteria 2JFRI@204428,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA OINAGBCE_02016 765952.PUV_18810 2.3e-68 265.8 Chlamydiae prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2JFZB@204428,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif OINAGBCE_02018 1444711.CCJF01000004_gene2358 4.1e-31 140.6 Chlamydiae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JG9Y@204428,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site OINAGBCE_02019 716544.wcw_0804 6.1e-11 72.4 Chlamydiae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2JGHY@204428,COG0257@1,COG0257@2 NA|NA|NA J Ribosomal protein L36 OINAGBCE_02020 1444712.BN1013_00881 9.4e-11 73.2 Chlamydiae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 2JGGJ@204428,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme OINAGBCE_02021 765952.PUV_19070 1.2e-27 129.8 Chlamydiae 5.3.4.1 ko:K01829 ko00000,ko01000 Bacteria 2JFZU@204428,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like OINAGBCE_02022 1444711.CCJF01000004_gene2367 4.5e-40 171.0 Chlamydiae ko:K09140 ko00000,ko03009 Bacteria 2JG7G@204428,COG2042@1,COG2042@2 NA|NA|NA S rRNA processing OINAGBCE_02023 1444711.CCJF01000004_gene2368 3.5e-122 445.3 Chlamydiae ko:K03310 ko00000 2.A.25 Bacteria 2JFVP@204428,COG1115@1,COG1115@2 NA|NA|NA P Sodium:alanine symporter family OINAGBCE_02024 1444711.CCJF01000004_gene2371 1.6e-141 509.6 Chlamydiae glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 2JFIT@204428,COG0297@1,COG0297@2 NA|NA|NA F Synthesizes alpha-1,4-glucan chains using ADP-glucose OINAGBCE_02025 1444711.CCJF01000004_gene2370 1.5e-65 256.1 Chlamydiae pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iIT341.HP1016,iJN678.pgsA,iSB619.SA_RS06365 Bacteria 2JFZD@204428,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family OINAGBCE_02026 716544.wcw_1235 1.1e-27 129.8 Chlamydiae phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 2JFXZ@204428,COG1235@1,COG1235@2 NA|NA|NA S Metallo-beta-lactamase superfamily OINAGBCE_02027 765952.PUV_14940 1.2e-122 446.8 Chlamydiae hflX ko:K03665 ko00000,ko03009 Bacteria 2JFSR@204428,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis OINAGBCE_02029 4565.Traes_7BL_8169D16DA.2 2.9e-07 64.3 Liliopsida Viridiplantae 37HF2@33090,3G8J9@35493,3KYK2@4447,COG0666@1,KOG0504@2759 NA|NA|NA O Ankyrin repeat OINAGBCE_02032 716544.wcw_0730 1.1e-15 90.5 Chlamydiae sscA ko:K15368 ko00000 Bacteria 2JHHW@204428,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat OINAGBCE_02033 314345.SPV1_04838 8.5e-122 444.1 Proteobacteria Bacteria 1MVW0@1224,COG3177@1,COG3177@2 NA|NA|NA S Filamentation induced by cAMP protein fic OINAGBCE_02034 765952.PUV_16690 1.7e-155 555.8 Chlamydiae mtaB 2.8.4.5 ko:K18707 R10649 RC00003,RC03221 ko00000,ko01000,ko03016 Bacteria 2JFUS@204428,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine OINAGBCE_02035 765952.PUV_16700 1e-36 161.0 Chlamydiae CP_0278 Bacteria 2C1EI@1,2JG5Y@204428,31PGH@2 NA|NA|NA # 1443 queries scanned # Total time (seconds): 27.701939106 # Rate: 52.09 q/s