# emapper version: emapper-2.0.1 emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 45 --temp_dir /media/bayegy/disk0/binning_test/Bin_all/emapper//bin.T11.63/_tmp -i /media/bayegy/disk0/binning_test/Bin_all/Bin_prokka//bin.T11.63/bin.T11.63.faa -o /media/bayegy/disk0/binning_test/Bin_all/emapper//bin.T11.63/bin.T11.63 --usemem --override # time: Wed Nov 3 17:18:05 2021 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. JOKFNDED_00002 1396418.BATQ01000098_gene6011 4.1e-44 185.3 Verrucomicrobiae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 2IUF6@203494,46X3R@74201,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ JOKFNDED_00003 1396141.BATP01000062_gene4454 3.2e-21 110.2 Verrucomicrobiae Bacteria 2CK49@1,2IW84@203494,2ZE58@2,46WV3@74201 NA|NA|NA JOKFNDED_00004 756272.Plabr_1391 1e-108 399.8 Planctomycetes 5.1.3.22,5.3.1.5 ko:K01805,ko:K03079 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R00878,R01432,R03244 RC00376,RC00516,RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXXX@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_00007 497964.CfE428DRAFT_4160 4.8e-61 243.4 Bacteria Bacteria COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily JOKFNDED_00008 1396418.BATQ01000010_gene3813 1.2e-28 132.5 Verrucomicrobiae Bacteria 2IVQF@203494,46UHN@74201,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon JOKFNDED_00012 240016.ABIZ01000001_gene1546 1.8e-193 682.2 Verrucomicrobiae xylB 1.1.1.57,2.7.1.17 ko:K00040,ko:K00854,ko:K19168 ko00040,ko01100,map00040,map01100 M00014,M00061 R01639,R02454 RC00002,RC00085,RC00538 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 2IUMH@203494,46SI1@74201,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, C-terminal domain JOKFNDED_00013 876044.IMCC3088_299 3.6e-25 122.9 Proteobacteria Bacteria 1PACH@1224,28W00@1,2ZI15@2 NA|NA|NA JOKFNDED_00014 1210884.HG799465_gene11717 7.9e-188 663.3 Planctomycetes 3.2.1.82 ko:K18650 ko00000,ko01000 GH28 Bacteria 2IYDB@203682,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_00015 344747.PM8797T_29862 2.3e-80 305.8 Planctomycetes 1.13.11.27,5.3.99.11 ko:K00457,ko:K06606 ko00130,ko00350,ko00360,ko00562,ko01100,ko01120,map00130,map00350,map00360,map00562,map01100,map01120 M00044 R01372,R02521,R09952 RC00505,RC00738,RC01513 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2J0ZG@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_00016 1396418.BATQ01000182_gene934 1.2e-178 632.9 Verrucomicrobiae Bacteria 2ITYT@203494,46U02@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_00017 1192034.CAP_2843 5.8e-61 241.5 Myxococcales Bacteria 1Q3M3@1224,2AJ61@1,2X4PF@28221,2YZCN@29,319QP@2,439EB@68525 NA|NA|NA JOKFNDED_00018 215803.DB30_1290 8.4e-11 73.2 Myxococcales Bacteria 1QABC@1224,2AN9F@1,2X92W@28221,2Z1MP@29,31D7J@2,434YD@68525 NA|NA|NA JOKFNDED_00020 1396141.BATP01000032_gene4277 8.1e-44 183.0 Verrucomicrobiae Bacteria 2CDIQ@1,2IW5Q@203494,33XFX@2,46VH5@74201 NA|NA|NA S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily JOKFNDED_00021 1396141.BATP01000047_gene3995 3.3e-50 205.3 Verrucomicrobia Bacteria 46U4I@74201,COG3210@1,COG3210@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_00023 240016.ABIZ01000001_gene276 1e-149 537.0 Verrucomicrobiae 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2ITY6@203494,46UAN@74201,COG0265@1,COG0265@2 NA|NA|NA O Trypsin JOKFNDED_00024 240016.ABIZ01000001_gene277 5e-122 444.9 Verrucomicrobiae 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2ITZC@203494,46SZ1@74201,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. JOKFNDED_00025 1396418.BATQ01000152_gene2406 1.7e-96 360.9 Verrucomicrobia 2.7.13.3 ko:K02482,ko:K14986 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 46TXI@74201,COG0784@1,COG0784@2,COG5002@1,COG5002@2 NA|NA|NA T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) JOKFNDED_00026 497964.CfE428DRAFT_1229 5e-77 294.7 Verrucomicrobia Bacteria 46UUM@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_00028 1396141.BATP01000056_gene3144 1.7e-86 326.2 Verrucomicrobiae fixC 1.3.99.38 ko:K21401 ko00000,ko01000 Bacteria 2IVKW@203494,46X3C@74201,COG0644@1,COG0644@2 NA|NA|NA C oxidoreductase JOKFNDED_00029 1396141.BATP01000056_gene3143 4.7e-45 188.0 Verrucomicrobiae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528,ko:K15256 R10716 RC00003,RC03257 ko00000,ko01000,ko03009,ko03016 Bacteria 2IUQN@203494,46WAR@74201,COG0030@1,COG0030@2 NA|NA|NA J 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity JOKFNDED_00030 1396418.BATQ01000142_gene3296 2.3e-125 455.7 Verrucomicrobiae Bacteria 2IWIQ@203494,46U83@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_00031 1403819.BATR01000164_gene5540 8.8e-95 353.6 Verrucomicrobia Bacteria 46UXG@74201,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family JOKFNDED_00032 1396418.BATQ01000151_gene2346 3.4e-59 234.6 Verrucomicrobiae gdh 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 2IV8W@203494,46S83@74201,COG4198@1,COG4198@2 NA|NA|NA S Protein of unknown function (DUF1015) JOKFNDED_00033 497964.CfE428DRAFT_1741 1.2e-42 179.5 Verrucomicrobia yqdE ko:K08999 ko00000 Bacteria 46SW6@74201,COG1259@1,COG1259@2 NA|NA|NA S Bifunctional nuclease JOKFNDED_00034 1396141.BATP01000030_gene3804 1.4e-27 130.6 Verrucomicrobiae ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 2IUNA@203494,46T4R@74201,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions JOKFNDED_00035 497964.CfE428DRAFT_1397 2e-34 151.8 Bacteria ko:K06940 ko00000 Bacteria COG0727@1,COG0727@2 NA|NA|NA S metal cluster binding JOKFNDED_00036 1396418.BATQ01000092_gene5835 1.3e-150 539.3 Verrucomicrobiae mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 2ITYI@203494,46SAA@74201,COG1077@1,COG1077@2 NA|NA|NA D Actin JOKFNDED_00037 1123070.KB899252_gene962 3.6e-43 182.2 Verrucomicrobiae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 2IUGV@203494,46T2J@74201,COG1792@1,COG1792@2 NA|NA|NA M rod shape-determining protein MreC JOKFNDED_00038 240016.ABIZ01000001_gene3225 3.1e-35 155.2 Verrucomicrobiae Bacteria 290WN@1,2IUR3@203494,2ZNIF@2,46WW0@74201 NA|NA|NA JOKFNDED_00039 1396418.BATQ01000092_gene5838 8.7e-160 570.9 Verrucomicrobiae 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 2ITQS@203494,46SE6@74201,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain JOKFNDED_00040 1300345.LF41_72 7.6e-09 68.2 Xanthomonadales rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 ko00000,ko01000,ko03009 Bacteria 1MVDX@1224,1RPAN@1236,1X407@135614,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil JOKFNDED_00041 1403819.BATR01000183_gene6323 3.7e-21 109.0 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_00042 1396418.BATQ01000007_gene1424 5.2e-79 301.2 Verrucomicrobiae glcK 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITKM@203494,46T0E@74201,COG1940@1,COG1940@2 NA|NA|NA GK ROK family JOKFNDED_00043 497964.CfE428DRAFT_5517 3.5e-58 231.9 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46VAM@74201,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_00045 1396141.BATP01000041_gene2220 1.4e-40 174.1 Verrucomicrobia Bacteria 2F2QZ@1,33VM9@2,46VCI@74201 NA|NA|NA JOKFNDED_00047 756272.Plabr_3033 6.8e-46 190.7 Bacteria ko:K07004 ko00000 Bacteria COG1409@1,COG1409@2 NA|NA|NA S acid phosphatase activity JOKFNDED_00049 1396418.BATQ01000007_gene1398 1.7e-205 722.2 Verrucomicrobiae rsr ko:K11089 ko05322,map05322 ko00000,ko00001 Bacteria 2IVI2@203494,46UN1@74201,COG2425@1,COG2425@2 NA|NA|NA S TROVE domain JOKFNDED_00050 240016.ABIZ01000001_gene5921 2.7e-219 768.1 Verrucomicrobiae rtcR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K14414 ko00000,ko03000 Bacteria 2IVC0@203494,46TFD@74201,COG4650@1,COG4650@2 NA|NA|NA KT Regulator of RNA terminal phosphate cyclase JOKFNDED_00051 1267535.KB906767_gene3472 6.8e-46 190.7 Acidobacteriia ko:K02479 ko00000,ko02022 Bacteria 2JJ28@204432,3Y4G0@57723,COG2197@1,COG2197@2 NA|NA|NA T Response regulator receiver JOKFNDED_00052 240016.ABIZ01000001_gene5541 1.4e-39 171.0 Verrucomicrobiae 2.7.13.3 ko:K11617 ko02020,map02020 M00481,M00754 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IV76@203494,46SBM@74201,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase JOKFNDED_00053 497964.CfE428DRAFT_3746 5.1e-52 211.8 Bacteria Bacteria 2F3W6@1,33WND@2 NA|NA|NA JOKFNDED_00055 1313421.JHBV01000041_gene3544 1.8e-34 152.5 Bacteroidetes fkpB 5.2.1.8 ko:K03772,ko:K03773 ko00000,ko01000,ko03110 Bacteria 4NDW4@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase JOKFNDED_00056 1122176.KB903565_gene3366 1.1e-68 266.5 Bacteroidetes Bacteria 4NWI7@976,COG4430@1,COG4430@2 NA|NA|NA S Psort location Cytoplasmic, score 8.96 JOKFNDED_00057 195253.Syn6312_1004 3.5e-55 221.5 Cyanobacteria Bacteria 1GDIA@1117,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family JOKFNDED_00058 1396141.BATP01000061_gene4533 7.3e-30 136.7 Verrucomicrobiae Bacteria 2IWEU@203494,46XRB@74201,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix JOKFNDED_00059 159087.Daro_3165 2.9e-25 122.1 Rhodocyclales Bacteria 1RFAR@1224,2C854@1,2KYTM@206389,2W2IN@28216,30DR2@2 NA|NA|NA S DinB superfamily JOKFNDED_00060 240016.ABIZ01000001_gene5522 7.6e-32 143.3 Verrucomicrobiae ogt 2.1.1.63 ko:K00567,ko:K07443 ko00000,ko01000,ko03400 Bacteria 2IVYU@203494,46VG4@74201,COG3695@1,COG3695@2 NA|NA|NA L 6-O-methylguanine DNA methyltransferase, DNA binding domain JOKFNDED_00061 1123242.JH636435_gene1968 2.8e-13 82.8 Planctomycetes Bacteria 2J4JX@203682,COG3319@1,COG3319@2 NA|NA|NA Q amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_00062 1396418.BATQ01000144_gene3457 4.8e-89 334.7 Verrucomicrobiae Bacteria 2IVAI@203494,46TRF@74201,COG2010@1,COG2010@2 NA|NA|NA C Domain of Unknown Function (DUF1080) JOKFNDED_00064 794903.OPIT5_13020 5.5e-41 175.3 Verrucomicrobia 3.1.3.6,3.1.4.16 ko:K01119,ko:K20276 ko00230,ko00240,ko02024,map00230,map00240,map02024 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 46VHC@74201,COG1404@1,COG1404@2,COG2755@1,COG2755@2 NA|NA|NA O lipolytic protein G-D-S-L family JOKFNDED_00065 395961.Cyan7425_2304 5.1e-147 527.7 Cyanothece uca 6.3.4.14,6.3.4.6,6.4.1.2 ko:K01941,ko:K01961 ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R00774,R04385 RC00040,RC00253,RC00367,RC00378 ko00000,ko00001,ko00002,ko01000 Bacteria 1G1M0@1117,3KG4Q@43988,COG0439@1,COG0439@2,COG1984@1,COG1984@2,COG2049@1,COG2049@2 NA|NA|NA I Carbamoyl-phosphate synthetase large chain domain protein JOKFNDED_00066 1538295.JY96_19660 1.3e-239 835.9 unclassified Burkholderiales uca 6.3.4.14,6.3.4.6,6.4.1.2 ko:K01941,ko:K01961 ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R00774,R04385 RC00040,RC00253,RC00367,RC00378 ko00000,ko00001,ko00002,ko01000 Bacteria 1KK2U@119065,1MU4H@1224,2WGI2@28216,COG0439@1,COG0439@2,COG1984@1,COG1984@2,COG2049@1,COG2049@2 NA|NA|NA EI Allophanate hydrolase subunit 2 JOKFNDED_00067 1396418.BATQ01000044_gene6451 9.8e-124 451.1 Verrucomicrobiae ko:K02481,ko:K07712 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko02022 Bacteria 2IU0F@203494,46SDB@74201,COG2204@1,COG2204@2 NA|NA|NA T Sigma-54 interaction domain JOKFNDED_00070 497964.CfE428DRAFT_4694 6.2e-89 334.7 Bacteria pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria COG0612@1,COG0612@2 NA|NA|NA L Peptidase, M16 JOKFNDED_00071 1396418.BATQ01000016_gene4196 1.7e-50 206.8 Verrucomicrobiae opcA Bacteria 2IUBI@203494,46V8B@74201,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit JOKFNDED_00072 235985.BBPN01000012_gene6949 5.5e-16 91.7 Streptacidiphilus Bacteria 2GMMM@201174,2NFP0@228398,COG1506@1,COG1506@2 NA|NA|NA E Dienelactone hydrolase family JOKFNDED_00073 1396418.BATQ01000136_gene3679 9.6e-130 470.3 Verrucomicrobiae Bacteria 2IUBE@203494,46V6M@74201,COG1657@1,COG1657@2 NA|NA|NA I Pectic acid lyase JOKFNDED_00074 794903.OPIT5_01995 5.2e-27 127.5 Opitutae vapC ko:K07064 ko00000 Bacteria 3K8HY@414999,46XWY@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_00075 794903.OPIT5_01990 2.6e-12 77.8 Opitutae GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 Bacteria 3K8HF@414999,46XWT@74201,COG4118@1,COG4118@2 NA|NA|NA D positive regulation of growth JOKFNDED_00077 1123269.NX02_21190 4.7e-18 98.6 Alphaproteobacteria Bacteria 1NCBQ@1224,2UIAE@28211,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family JOKFNDED_00078 1123278.KB893575_gene1429 1.1e-82 313.5 Cytophagia 2.1.1.37,3.1.21.4 ko:K00558,ko:K01155 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 47MK0@768503,4PN53@976,COG0270@1,COG0270@2 NA|NA|NA L BsuBI/PstI restriction endonuclease C-terminus JOKFNDED_00079 765420.OSCT_0137 4e-115 421.4 Chloroflexia GO:0003674,GO:0003824,GO:0003886,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009008,GO:0009307,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044728,GO:0046483,GO:0050896,GO:0071704,GO:0090116,GO:0090304,GO:0099046,GO:0140097,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 2GA0C@200795,377KZ@32061,COG0270@1,COG0270@2 NA|NA|NA H C-5 cytosine-specific DNA methylase JOKFNDED_00080 1403819.BATR01000031_gene960 2.7e-98 365.5 Bacteria 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 R00191 RC00296 ko00000,ko00001,ko01000 Bacteria COG1409@1,COG1409@2 NA|NA|NA S acid phosphatase activity JOKFNDED_00081 1254432.SCE1572_23865 1.1e-15 89.4 Myxococcales ydzA Bacteria 1N9NR@1224,2WXBD@28221,2YVSG@29,43BA7@68525,COG0477@1,COG2814@2 NA|NA|NA EGP Domain of unknown function (DUF3817) JOKFNDED_00083 1385512.N784_03015 2.1e-19 102.1 Pontibacillus yuxK Bacteria 1V7DJ@1239,2YANF@289201,4HIUD@91061,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 JOKFNDED_00084 349741.Amuc_0550 3.2e-33 148.3 Verrucomicrobiae yocH ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2IUCH@203494,46VUB@74201,COG3584@1,COG3584@2 NA|NA|NA S 3D domain JOKFNDED_00085 1396141.BATP01000057_gene3003 6.6e-118 430.6 Verrucomicrobiae aguA 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 R01416 RC00177 ko00000,ko00001,ko01000 Bacteria 2IU1P@203494,46SAM@74201,COG2957@1,COG2957@2 NA|NA|NA E Porphyromonas-type peptidyl-arginine deiminase JOKFNDED_00086 595460.RRSWK_04758 1.2e-23 116.3 Bacteria Bacteria 2E5WH@1,32RS6@2 NA|NA|NA J 23S rRNA-intervening sequence protein JOKFNDED_00087 240016.ABIZ01000001_gene1605 8.4e-114 416.8 Verrucomicrobiae aguB 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 R01152 RC00096 ko00000,ko00001,ko01000 Bacteria 2ITNA@203494,46S7B@74201,COG0388@1,COG0388@2 NA|NA|NA K Carbon-nitrogen hydrolase JOKFNDED_00088 344747.PM8797T_16173 4.4e-65 255.0 Planctomycetes Bacteria 2IZ4H@203682,COG0657@1,COG0657@2 NA|NA|NA G COG0657 Esterase lipase JOKFNDED_00089 1519464.HY22_11920 5e-61 242.3 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_00090 1403819.BATR01000118_gene4076 2.7e-107 395.6 Verrucomicrobiae 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2ITWF@203494,46U97@74201,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase JOKFNDED_00091 404380.Gbem_1821 2e-26 126.7 Deltaproteobacteria Bacteria 1NP5P@1224,2E0WZ@1,2WW5V@28221,30TPT@2,430GV@68525 NA|NA|NA JOKFNDED_00092 794903.OPIT5_14685 1.4e-123 449.9 Opitutae ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 3K7SW@414999,46SA2@74201,COG1252@1,COG1252@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase JOKFNDED_00094 1123242.JH636435_gene1598 1e-93 350.1 Planctomycetes ko:K01463 ko00000,ko01000 Bacteria 2IY80@203682,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase JOKFNDED_00095 1307834.BARL01000001_gene708 8.6e-14 83.6 Rhodospirillales Bacteria 1N6RE@1224,2JU2B@204441,2UHTX@28211,COG4704@1,COG4704@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2141) JOKFNDED_00096 1396141.BATP01000035_gene4130 3.4e-29 136.0 Verrucomicrobiae Bacteria 2BVZ5@1,2IUT3@203494,2ZX54@2,46WWN@74201 NA|NA|NA JOKFNDED_00097 1499967.BAYZ01000167_gene6747 7.5e-82 311.6 Bacteria lepB_1 2.1.1.80,3.1.1.61,3.1.21.3 ko:K01153,ko:K13924,ko:K15492 ko02020,ko02030,ko05134,map02020,map02030,map05134 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02048 Bacteria COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation JOKFNDED_00098 344747.PM8797T_17809 4.5e-54 218.8 Planctomycetes 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2IX9U@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase JOKFNDED_00099 497964.CfE428DRAFT_0982 0.0 1120.5 Verrucomicrobia Bacteria 46TQ0@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1553) JOKFNDED_00100 643867.Ftrac_0076 1.4e-46 192.6 Cytophagia nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 47P7M@768503,4NMHV@976,COG0494@1,COG0494@2 NA|NA|NA L pfam nudix JOKFNDED_00101 497964.CfE428DRAFT_2729 1.4e-79 302.8 Verrucomicrobia 2.3.1.157,2.7.7.23,2.7.7.24 ko:K00973,ko:K04042 ko00520,ko00521,ko00523,ko00525,ko01100,ko01130,map00520,map00521,map00523,map00525,map01100,map01130 M00362,M00793 R00416,R02328,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 46T9Q@74201,COG1209@1,COG1209@2 NA|NA|NA M Nucleotidyl transferase JOKFNDED_00102 240016.ABIZ01000001_gene2667 6.3e-152 543.9 Verrucomicrobiae yugH 2.6.1.1 ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 2ITGM@203494,46SFZ@74201,COG0436@1,COG0436@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme JOKFNDED_00103 1396141.BATP01000003_gene4916 4.9e-47 194.1 Verrucomicrobiae alaR Bacteria 2IU8W@203494,46VEI@74201,COG1522@1,COG1522@2 NA|NA|NA K Lrp/AsnC ligand binding domain JOKFNDED_00104 1396141.BATP01000003_gene4913 9.3e-139 500.0 Verrucomicrobiae pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iJN678.pfkA Bacteria 2ITQA@203494,46SFN@74201,COG0205@1,COG0205@2 NA|NA|NA G Phosphofructokinase JOKFNDED_00105 1396141.BATP01000003_gene4912 8.4e-48 197.6 Verrucomicrobiae 3.4.16.4,6.3.2.10 ko:K01929,ko:K07258 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2IU96@203494,46VPH@74201,COG1686@1,COG1686@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase JOKFNDED_00106 1396141.BATP01000024_gene879 6.6e-07 60.5 Verrucomicrobiae Bacteria 2A0RX@1,2IW8P@203494,30MWM@2,46XN7@74201 NA|NA|NA JOKFNDED_00108 1396418.BATQ01000104_gene5500 1.5e-64 252.7 Verrucomicrobiae ymaB Bacteria 2IU8G@203494,46V3C@74201,COG4112@1,COG4112@2 NA|NA|NA JOKFNDED_00109 1123070.KB899249_gene293 3.4e-35 155.2 Verrucomicrobiae Bacteria 2IUNS@203494,46SX5@74201,COG2345@1,COG2345@2 NA|NA|NA K Transcriptional regulator JOKFNDED_00110 1403819.BATR01000112_gene3749 3.7e-173 614.4 Verrucomicrobiae kamA 5.4.3.2 ko:K01843 ko00310,map00310 R00461 RC00303 ko00000,ko00001,ko01000 Bacteria 2ITNU@203494,46SVQ@74201,COG1509@1,COG1509@2 NA|NA|NA E Lysine-2,3-aminomutase JOKFNDED_00112 1396141.BATP01000003_gene5202 6.2e-121 440.7 Verrucomicrobiae moxR ko:K03924 ko00000,ko01000 Bacteria 2ITT6@203494,46S9V@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_00114 1396141.BATP01000060_gene4654 8e-42 176.8 Verrucomicrobiae cyaA GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUZ6@203494,46VEE@74201,COG2954@1,COG2954@2 NA|NA|NA S CYTH JOKFNDED_00115 497964.CfE428DRAFT_1764 4.9e-43 181.0 Verrucomicrobia rfaY ko:K03088 ko00000,ko03021 Bacteria 46V4Y@74201,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_00116 497964.CfE428DRAFT_1763 3.8e-100 372.1 Verrucomicrobia Bacteria 46TPT@74201,COG3712@1,COG3712@2 NA|NA|NA PT FecR protein JOKFNDED_00117 1403819.BATR01000118_gene4072 6.1e-266 924.1 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_00118 497964.CfE428DRAFT_1761 1.1e-192 679.5 Verrucomicrobia Bacteria 46TG2@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00119 1396141.BATP01000020_gene54 1.8e-51 209.5 Verrucomicrobiae ko:K07090 ko00000 Bacteria 2IUFA@203494,46VE4@74201,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE JOKFNDED_00120 1123508.JH636440_gene2173 5.5e-18 97.1 Planctomycetes Bacteria 2IWZF@203682,COG4403@1,COG4403@2 NA|NA|NA V Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella JOKFNDED_00121 497964.CfE428DRAFT_0238 2.4e-79 302.0 Verrucomicrobia Bacteria 46TSG@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_00122 1123242.JH636434_gene4354 1.9e-200 705.3 Planctomycetes Bacteria 2IX5T@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00123 1123070.KB899252_gene827 2.2e-149 535.4 Verrucomicrobiae lldD 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 Bacteria 2IUJ3@203494,46U3I@74201,COG1304@1,COG1304@2 NA|NA|NA C FMN-dependent dehydrogenase JOKFNDED_00124 497964.CfE428DRAFT_3584 2.7e-150 538.5 Verrucomicrobia Bacteria 46U7U@74201,COG5441@1,COG5441@2 NA|NA|NA S Uncharacterised protein family (UPF0261) JOKFNDED_00125 1396141.BATP01000001_gene5310 7.3e-126 456.8 Verrucomicrobiae Bacteria 2IVH6@203494,46TKF@74201,COG5564@1,COG5564@2 NA|NA|NA S Phosphoenolpyruvate hydrolase-like JOKFNDED_00126 313628.LNTAR_07981 5.1e-69 268.1 Bacteria mltR Bacteria COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator JOKFNDED_00127 886293.Sinac_1210 1.5e-215 756.5 Planctomycetes Bacteria 2IXBQ@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_00128 1123242.JH636435_gene2770 1.1e-179 636.3 Planctomycetes Bacteria 2IXN0@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00130 414684.RC1_3800 8e-18 97.8 Rhodospirillales 1.14.13.238 ko:K22342 ko00000,ko01000 Bacteria 1N6CK@1224,2DB9X@1,2JWW7@204441,2U2ME@28211,2Z7ZS@2 NA|NA|NA S Protein of unknown function (DUF3445) JOKFNDED_00131 497964.CfE428DRAFT_5147 1e-66 260.8 Bacteria ko:K07001 ko00000 Bacteria COG1752@1,COG1752@2 NA|NA|NA M Esterase of the alpha-beta hydrolase superfamily JOKFNDED_00132 497964.CfE428DRAFT_5146 5e-162 577.8 Verrucomicrobia 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 46UTU@74201,COG1541@1,COG1541@2 NA|NA|NA H AMP-binding enzyme JOKFNDED_00133 1396141.BATP01000060_gene4700 9.1e-141 506.9 Verrucomicrobiae fadA 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITN0@203494,46U9D@74201,COG0183@1,COG0183@2 NA|NA|NA I Thiolase, C-terminal domain JOKFNDED_00134 1396141.BATP01000060_gene4699 9.3e-172 610.5 Verrucomicrobiae yfcX 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITMD@203494,46U5Q@74201,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain JOKFNDED_00135 497964.CfE428DRAFT_5143 1.8e-214 752.3 Verrucomicrobia fadE10 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 46TJY@74201,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain JOKFNDED_00136 1396141.BATP01000058_gene1978 2.5e-103 382.5 Verrucomicrobiae 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 2IV73@203494,46XAK@74201,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase JOKFNDED_00137 1121100.JCM6294_3738 1.3e-48 200.7 Bacteroidaceae ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 ko00000,ko00001,ko02042 Bacteria 2FP2U@200643,4AKNC@815,4NKT5@976,COG0467@1,COG0467@2 NA|NA|NA T COG NOG06399 non supervised orthologous group JOKFNDED_00138 1396141.BATP01000005_gene5946 8.7e-102 376.7 Verrucomicrobiae folE2 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU2Z@203494,46SIB@74201,COG1469@1,COG1469@2 NA|NA|NA S Type I GTP cyclohydrolase folE2 JOKFNDED_00139 1403819.BATR01000031_gene1024 4.1e-145 521.2 Verrucomicrobiae Bacteria 2IV1M@203494,46TN3@74201,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family JOKFNDED_00140 344747.PM8797T_07964 1.1e-91 343.6 Planctomycetes Bacteria 2J286@203682,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_00141 1396418.BATQ01000125_gene5093 7.2e-64 251.1 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_00142 243090.RB12089 5.6e-195 687.2 Planctomycetes 3.1.6.13 ko:K01136,ko:K01138 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00078 R07812,R07821 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYSH@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_00145 1396418.BATQ01000157_gene2436 4.4e-80 306.2 Verrucomicrobiae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2IUFR@203494,46T3W@74201,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein JOKFNDED_00146 1396418.BATQ01000075_gene656 3.3e-38 165.6 Verrucomicrobiae yocH ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2IUCH@203494,46VUB@74201,COG3584@1,COG3584@2 NA|NA|NA S 3D domain JOKFNDED_00147 1123070.KB899267_gene2478 4.8e-90 337.4 Verrucomicrobiae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IU17@203494,46T2G@74201,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate JOKFNDED_00148 1396141.BATP01000007_gene5764 2.9e-190 671.4 Verrucomicrobiae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 2ITYG@203494,46SCU@74201,COG0137@1,COG0137@2 NA|NA|NA E Arginosuccinate synthase JOKFNDED_00149 278957.ABEA03000060_gene3067 7.6e-33 146.4 Opitutae ppnP 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 3K88M@414999,46VVG@74201,COG3123@1,COG3123@2 NA|NA|NA S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions JOKFNDED_00150 1396141.BATP01000036_gene3839 8.4e-54 216.9 Verrucomicrobiae Bacteria 2IW4D@203494,46VXB@74201,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_00151 1396141.BATP01000005_gene6010 4.3e-217 760.8 Verrucomicrobiae mdoG GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:1901576 ko:K03670 ko00000 Bacteria 2IVA1@203494,46UGJ@74201,COG3131@1,COG3131@2 NA|NA|NA P Periplasmic glucan biosynthesis protein, MdoG JOKFNDED_00152 1123242.JH636435_gene2267 3.3e-40 172.2 Planctomycetes Bacteria 2J0Z6@203682,COG1414@1,COG1414@2 NA|NA|NA K Transcriptional regulator JOKFNDED_00153 452637.Oter_3956 1.3e-24 119.4 Opitutae Bacteria 3K9KN@414999,46YHH@74201,COG1487@1,COG1487@2 NA|NA|NA S ribonuclease activity JOKFNDED_00155 756272.Plabr_3075 0.0 1174.5 Planctomycetes Bacteria 2J24D@203682,COG2010@1,COG2010@2 NA|NA|NA C Concanavalin A-like lectin/glucanases superfamily JOKFNDED_00156 756272.Plabr_3074 1.2e-184 652.9 Planctomycetes Bacteria 2J285@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00157 1384054.N790_05245 1.8e-75 290.0 Gammaproteobacteria ko:K03286 ko00000,ko02000 1.B.6 Bacteria 1REH1@1224,1S4WV@1236,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family JOKFNDED_00158 756272.Plabr_0562 1.7e-15 87.8 Bacteria Bacteria COG3356@1,COG3356@2 NA|NA|NA JOKFNDED_00159 768671.ThimaDRAFT_0310 1.1e-82 313.5 Chromatiales ko:K07454 ko00000 Bacteria 1NE0N@1224,1RNM6@1236,1WZSF@135613,COG3440@1,COG3440@2 NA|NA|NA V HNH endonuclease JOKFNDED_00160 335543.Sfum_2038 8.9e-07 61.2 Syntrophobacterales comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1Q2CD@1224,2MSET@213462,2X38P@28221,437YR@68525,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif JOKFNDED_00161 1122194.AUHU01000012_gene326 2.6e-200 705.3 Alteromonadaceae Bacteria 1MWW6@1224,1RYRU@1236,469BD@72275,COG0210@1,COG0210@2 NA|NA|NA L AAA domain JOKFNDED_00162 1123401.JHYQ01000006_gene6 2.8e-28 132.1 Gammaproteobacteria ko:K06860 ko00000 Bacteria 1REF0@1224,1S545@1236,COG1432@1,COG1432@2 NA|NA|NA V HNH endonuclease JOKFNDED_00163 313628.LNTAR_17698 3.5e-122 446.0 Bacteria 2.7.1.83 ko:K03555,ko:K16328 ko00240,ko03430,map00240,map03430 R03315 RC00002,RC00017 ko00000,ko00001,ko01000,ko03400 Bacteria COG1403@1,COG1403@2,COG2227@1,COG2227@2,COG2932@1,COG2932@2 NA|NA|NA K sequence-specific DNA binding JOKFNDED_00166 530564.Psta_0006 7.4e-102 377.1 Planctomycetes katN ko:K07217 ko00000 Bacteria 2IXFJ@203682,COG3546@1,COG3546@2 NA|NA|NA P Manganese containing catalase JOKFNDED_00168 1207075.PputUW4_00139 8e-17 93.2 Gammaproteobacteria hcaD 1.18.1.1,1.7.1.15 ko:K00362,ko:K00363,ko:K05297,ko:K05710 ko00071,ko00360,ko00910,ko01120,ko01220,map00071,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R02000,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 1NR3M@1224,1RY7C@1236,COG0446@1,COG0446@2,COG2146@1,COG2146@2 NA|NA|NA P pyridine nucleotide-disulfide oxidoreductase JOKFNDED_00169 313606.M23134_03369 1.6e-22 113.2 Cytophagia Bacteria 28PZI@1,2ZCIU@2,47STT@768503,4NN9K@976 NA|NA|NA JOKFNDED_00170 378806.STAUR_4979 8e-09 68.9 Myxococcales fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 ko:K02283,ko:K03609 ko00000,ko02035,ko02044,ko03036,ko04812 Bacteria 1R7EN@1224,2WIYX@28221,2YTSI@29,42NAK@68525,COG1716@1,COG1716@2,COG4962@1,COG4962@2 NA|NA|NA TU Type II IV secretion system protein JOKFNDED_00172 1519464.HY22_11920 1.6e-61 243.8 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_00173 1173024.KI912149_gene5262 1.9e-63 250.8 Stigonemataceae add 2.7.13.3,3.5.4.2,3.5.4.4 ko:K01488,ko:K07711,ko:K21053 ko00230,ko01100,ko02020,ko02024,ko05340,map00230,map01100,map02020,map02024,map05340 M00502 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1GK1J@1117,1JKBT@1189,COG1816@1,COG1816@2,COG2202@1,COG2202@2,COG2204@1,COG2204@2,COG4191@1,COG4191@2,COG5278@1,COG5278@2 NA|NA|NA T CHASE3 domain JOKFNDED_00174 497964.CfE428DRAFT_5839 1.2e-74 287.0 Verrucomicrobia Bacteria 46V9J@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_00175 1396418.BATQ01000085_gene1120 5.1e-24 117.9 Verrucomicrobiae ftsA ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 2ITMT@203494,46SQI@74201,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring JOKFNDED_00176 1123070.KB899263_gene1749 8.8e-94 351.3 Verrucomicrobiae ftsZ ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 2ITWH@203494,46UWD@74201,COG0206@1,COG0206@2 NA|NA|NA D Tubulin/FtsZ family, GTPase domain JOKFNDED_00177 697281.Mahau_1689 2e-13 82.0 Thermoanaerobacterales ko:K07090 ko00000 Bacteria 1VAMI@1239,24MXA@186801,42GYA@68295,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein JOKFNDED_00178 1403819.BATR01000065_gene1935 2.9e-82 312.4 Verrucomicrobiae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2ITP3@203494,46T5Y@74201,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III, delta subunit JOKFNDED_00179 234267.Acid_1875 3.7e-20 105.5 Bacteria Bacteria COG2885@1,COG2885@2 NA|NA|NA M chlorophyll binding JOKFNDED_00180 1403819.BATR01000134_gene4803 8e-152 543.5 Verrucomicrobiae aspC 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 2ITV6@203494,46S4M@74201,COG0436@1,COG0436@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family JOKFNDED_00183 313628.LNTAR_08066 2.6e-227 795.8 Bacteria 1.1.5.2 ko:K00117,ko:K02305,ko:K08738 ko00030,ko00910,ko00920,ko01100,ko01110,ko01120,ko01130,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00030,map00910,map00920,map01100,map01110,map01120,map01130,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R06620,R10151 RC00066,RC02794,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.10,3.D.4.6 Bacteria COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3474@1,COG3474@2 NA|NA|NA C electron transfer activity JOKFNDED_00185 240016.ABIZ01000001_gene432 1.2e-97 364.0 Verrucomicrobia GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K00786 ko00000,ko01000 Bacteria 46SSE@74201,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase JOKFNDED_00186 1396141.BATP01000032_gene4397 6.1e-37 162.9 Verrucomicrobiae ank2 3.2.2.9 ko:K01243,ko:K06867 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVP5@203494,46VM6@74201,COG0666@1,COG0666@2,COG1376@1,COG1376@2 NA|NA|NA S Ankyrin repeats (3 copies) JOKFNDED_00187 714943.Mucpa_6358 5.5e-42 178.3 Bacteria mgsA Bacteria COG1597@1,COG1597@2 NA|NA|NA I lipid kinase activity JOKFNDED_00188 1396141.BATP01000059_gene2468 1.5e-62 246.1 Verrucomicrobiae Bacteria 2IU6U@203494,46SS3@74201,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_00189 1396141.BATP01000059_gene2467 7.7e-74 284.6 Verrucomicrobiae 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2ITKV@203494,46SSA@74201,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain JOKFNDED_00190 211114.JOEF01000025_gene185 9.3e-33 148.7 Actinobacteria Bacteria 2IBAX@201174,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily JOKFNDED_00192 1396141.BATP01000009_gene2657 3.6e-105 387.9 Verrucomicrobiae thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 Bacteria 2ITYP@203494,46SHY@74201,COG2022@1,COG2022@2 NA|NA|NA H Thiazole biosynthesis protein ThiG JOKFNDED_00193 1122963.AUHB01000002_gene1055 4e-27 127.9 Methylocystaceae mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1RHG8@1224,2U99Y@28211,36YJ6@31993,COG1970@1,COG1970@2 NA|NA|NA M Large-conductance mechanosensitive channel, MscL JOKFNDED_00194 1396418.BATQ01000184_gene2606 9e-34 150.6 Verrucomicrobiae ko:K06893 ko00000 Bacteria 2IW1M@203494,46WZQ@74201,COG2863@1,COG2863@2 NA|NA|NA C Cytochrome c JOKFNDED_00195 1403819.BATR01000154_gene5164 4.2e-19 102.1 Verrucomicrobiae Bacteria 2DN50@1,2IUH5@203494,32VJ4@2,46V62@74201 NA|NA|NA S Domain of unknown function (DUF4340) JOKFNDED_00196 195250.CM001776_gene2699 6.8e-09 68.6 Synechococcus Bacteria 1GND9@1117,1H0SG@1129,2DN50@1,32VJ4@2 NA|NA|NA S Domain of unknown function (DUF4340) JOKFNDED_00197 1396418.BATQ01000075_gene658 1.3e-20 106.7 Verrucomicrobiae gldG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IU4Y@203494,46SRK@74201,COG3225@1,COG3225@2 NA|NA|NA N ABC-type uncharacterized transport system JOKFNDED_00198 1396418.BATQ01000045_gene6087 1e-208 733.4 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_00199 1403819.BATR01000182_gene6260 7.6e-202 709.9 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00201 240016.ABIZ01000001_gene4003 9.5e-58 230.3 Verrucomicrobiae Bacteria 2IVPP@203494,46STY@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_00202 883126.HMPREF9710_00736 1.9e-17 96.3 Bacteria ko:K01446 R04112 RC00064,RC00141 ko00000 Bacteria COG3876@1,COG3876@2 NA|NA|NA G Protein conserved in bacteria JOKFNDED_00203 1396418.BATQ01000117_gene4589 3.9e-130 471.9 Verrucomicrobiae topA 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 2ITTZ@203494,46S97@74201,COG0550@1,COG0550@2 NA|NA|NA L Bacterial DNA topoisomeraes I ATP-binding domain JOKFNDED_00205 794903.OPIT5_13605 3.3e-77 297.7 Opitutae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 3K9Q3@414999,46UU9@74201,COG3210@1,COG3210@2,COG3420@1,COG3420@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_00206 1403819.BATR01000114_gene3978 8.1e-13 81.3 Verrucomicrobiae Bacteria 29WV2@1,2IUYJ@203494,30IGJ@2,46WPV@74201 NA|NA|NA S Tetratricopeptide repeat-like domain JOKFNDED_00207 1396141.BATP01000040_gene2153 7.8e-83 314.3 Verrucomicrobiae nagA 3.5.1.25 ko:K01443,ko:K16786,ko:K16787 ko00520,ko01130,ko02010,map00520,map01130,map02010 M00582 R02059 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IU36@203494,46SRF@74201,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family JOKFNDED_00209 1123070.KB899247_gene1452 7.3e-92 344.0 Verrucomicrobiae yceA ko:K07146 ko00000 Bacteria 2IUAG@203494,46VK6@74201,COG1054@1,COG1054@2 NA|NA|NA J Rhodanese Homology Domain JOKFNDED_00211 1396418.BATQ01000182_gene856 1.4e-174 619.4 Verrucomicrobiae miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2ITRH@203494,46S6B@74201,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine JOKFNDED_00212 1396141.BATP01000030_gene3782 7.2e-37 160.6 Verrucomicrobiae Bacteria 2EEN4@1,2IUHT@203494,338G1@2,46T5X@74201 NA|NA|NA JOKFNDED_00215 1396141.BATP01000039_gene1360 0.0 1414.4 Verrucomicrobiae mexF ko:K18299,ko:K18902,ko:K19585 M00641,M00698,M00767 ko00000,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.16,2.A.6.2.47 Bacteria 2ITVP@203494,46U0U@74201,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family JOKFNDED_00216 794903.OPIT5_25955 6.7e-82 311.2 Opitutae mexE ko:K18298,ko:K18901,ko:K19586,ko:K19595 M00641,M00698,M00767,M00768,M00769 ko00000,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.25,2.A.6.2.34,2.A.6.2.47,8.A.1 Bacteria 3K865@414999,46UG5@74201,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_00217 1396418.BATQ01000017_gene4169 6.2e-47 194.1 Verrucomicrobiae ko:K16137 ko00000,ko03000 Bacteria 2IUYV@203494,46U8N@74201,COG1309@1,COG1309@2 NA|NA|NA K Bacterial transcriptional repressor C-terminal JOKFNDED_00218 497964.CfE428DRAFT_5612 4.8e-59 235.0 Verrucomicrobia Bacteria 46SGH@74201,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain JOKFNDED_00219 1403819.BATR01000055_gene1726 1.3e-112 413.3 Bacteria mexE2 ko:K18298,ko:K19586 M00641,M00767 ko00000,ko00002,ko01504,ko02000 2.A.6.2.47,8.A.1 Bacteria COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_00220 926549.KI421517_gene1362 2.2e-145 522.7 Cytophagia Bacteria 47NEH@768503,4NF52@976,COG0471@1,COG0471@2 NA|NA|NA P COGs COG0471 Di- and tricarboxylate transporter JOKFNDED_00221 240016.ABIZ01000001_gene2129 2.7e-117 428.7 Verrucomicrobiae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 2IVFG@203494,46U9R@74201,COG3158@1,COG3158@2 NA|NA|NA P K+ potassium transporter JOKFNDED_00222 1396141.BATP01000019_gene1727 2.9e-134 485.0 Verrucomicrobiae bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1589,iZ_1308.Z0994 Bacteria 2ITKQ@203494,46S63@74201,COG0502@1,COG0502@2 NA|NA|NA H Biotin and Thiamin Synthesis associated domain JOKFNDED_00223 240016.ABIZ01000001_gene695 8.7e-64 250.4 Verrucomicrobiae Bacteria 2A8AI@1,2IU9U@203494,30XBY@2,46SPH@74201 NA|NA|NA JOKFNDED_00224 240016.ABIZ01000001_gene4861 1.2e-69 270.0 Verrucomicrobiae xlyA 3.5.1.28 ko:K01447 R04112 RC00064,RC00141 ko00000,ko01000 Bacteria 2IU5K@203494,46VKP@74201,COG5632@1,COG5632@2 NA|NA|NA M PFAM N-acetylmuramoyl-L-alanine amidase family 2 JOKFNDED_00225 1396141.BATP01000032_gene4366 2.3e-47 194.9 Verrucomicrobiae gloA GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042182,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046872,GO:0046914,GO:0051186,GO:0051596,GO:0061727,GO:0071704,GO:1901564,GO:1901575,GO:1901615 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 iAPECO1_1312.APECO1_733,iECABU_c1320.ECABU_c19040,iECED1_1282.ECED1_1851,iECNA114_1301.ECNA114_1699,iECOK1_1307.ECOK1_1770,iECP_1309.ECP_1597,iECS88_1305.ECS88_1700,iECSF_1327.ECSF_1514,iLF82_1304.LF82_0861,iNRG857_1313.NRG857_08275,iUMN146_1321.UM146_08895,iUTI89_1310.UTI89_C1842,ic_1306.c2044 Bacteria 2IUKG@203494,46SUF@74201,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily JOKFNDED_00226 344747.PM8797T_04075 1.6e-16 93.6 Bacteria Bacteria 2F6VH@1,33ZBM@2 NA|NA|NA JOKFNDED_00227 1396418.BATQ01000063_gene1603 4.2e-149 534.3 Verrucomicrobiae 2.1.1.302 ko:K21377 ko00000,ko01000 Bacteria 2IV1W@203494,46X8X@74201,COG0500@1,COG2226@2 NA|NA|NA Q Dimerisation domain JOKFNDED_00228 870187.Thini_0062 1.5e-10 72.0 Gammaproteobacteria Bacteria 1NBSZ@1224,1SH94@1236,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module JOKFNDED_00229 545695.TREAZ_1967 3.1e-26 124.8 Bacteria vapC ko:K07062 ko00000,ko01000,ko02048 Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_00231 1283300.ATXB01000001_gene388 0.0 1132.9 Gammaproteobacteria atsD GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MV92@1224,1RPDE@1236,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00232 1121904.ARBP01000086_gene1909 3.5e-22 111.7 Bacteria Bacteria 29XXX@1,30JQG@2 NA|NA|NA JOKFNDED_00233 216596.RL3058 5.7e-181 640.6 Rhizobiaceae Bacteria 1MWTW@1224,2TUR1@28211,4B93D@82115,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1254) JOKFNDED_00234 1547445.LO80_04115 1e-36 161.0 Gammaproteobacteria GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1NBVB@1224,1SES6@1236,COG5361@1,COG5361@2 NA|NA|NA S Neurotransmitter-gated ion-channel ligand binding domain JOKFNDED_00235 497964.CfE428DRAFT_3821 0.0 1160.2 Verrucomicrobia ko:K02453,ko:K02666,ko:K12282 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 46W4R@74201,COG1450@1,COG1450@2 NA|NA|NA NU Type ii and iii secretion system protein JOKFNDED_00236 555779.Dthio_PD2126 2.2e-40 172.2 Deltaproteobacteria Bacteria 1RGWX@1224,2WPHJ@28221,42TA9@68525,COG0449@1,COG0449@2 NA|NA|NA M ORF6N domain JOKFNDED_00237 497964.CfE428DRAFT_4129 1.3e-34 152.5 Verrucomicrobia Bacteria 46T5V@74201,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase JOKFNDED_00238 1123070.KB899269_gene2397 2.4e-49 202.2 Verrucomicrobiae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2IUBK@203494,46T5A@74201,COG0220@1,COG0220@2 NA|NA|NA J Putative methyltransferase JOKFNDED_00239 1403819.BATR01000087_gene2582 1.2e-06 60.1 Bacteria Bacteria 2DS3G@1,33ECD@2 NA|NA|NA JOKFNDED_00240 497964.CfE428DRAFT_3033 3.8e-39 168.3 Verrucomicrobia bioD GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_0821,iECIAI1_1343.ECIAI1_0813,iECO103_1326.ECO103_0813,iECO111_1330.ECO111_0839,iECO26_1355.ECO26_0904,iECSE_1348.ECSE_0831,iECW_1372.ECW_m0833,iEKO11_1354.EKO11_3108,iEcE24377_1341.EcE24377A_0841,iSFV_1184.SFV_0761,iSSON_1240.SSON_0757,iWFL_1372.ECW_m0833,ic_1306.c0858 Bacteria 46VJB@74201,COG0132@1,COG0132@2 NA|NA|NA H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring JOKFNDED_00241 1396418.BATQ01000133_gene4044 6.1e-124 451.1 Verrucomicrobiae glmM 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 Bacteria 2ITTH@203494,46SJ2@74201,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, C-terminal domain JOKFNDED_00243 1396418.BATQ01000056_gene232 1.9e-67 262.7 Verrucomicrobiae dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 2IU56@203494,46SSQ@74201,COG1624@1,COG1624@2 NA|NA|NA S DisA bacterial checkpoint controller nucleotide-binding JOKFNDED_00244 1403819.BATR01000134_gene4802 8.9e-57 226.5 Verrucomicrobiae ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006720,GO:0006721,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0030145,GO:0040007,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051483,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K00991,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c,iPC815.YPO3360 Bacteria 2IUAJ@203494,46T29@74201,COG0245@1,COG0245@2 NA|NA|NA I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) JOKFNDED_00245 1123070.KB899268_gene2432 6.2e-73 280.8 Verrucomicrobiae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU5U@203494,46T0Z@74201,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family JOKFNDED_00247 1403819.BATR01000154_gene5160 0.0 1078.5 Verrucomicrobiae sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 2ITMJ@203494,46S6G@74201,COG0567@1,COG0567@2 NA|NA|NA C 2-oxoglutarate dehydrogenase C-terminal JOKFNDED_00248 382245.ASA_0113 1.3e-11 78.6 Aeromonadales pncB GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009266,GO:0009408,GO:0009435,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046496,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iAF1260.b0931,iBWG_1329.BWG_0783,iECDH10B_1368.ECDH10B_1001,iECDH1ME8569_1439.ECDH1ME8569_0882,iECIAI39_1322.ECIAI39_2216,iETEC_1333.ETEC_0999,iEcDH1_1363.EcDH1_2712,iEcSMS35_1347.EcSMS35_2189,iJO1366.b0931,iJR904.b0931,iUMNK88_1353.UMNK88_1085,iY75_1357.Y75_RS04840 Bacteria 1MV8U@1224,1RQWS@1236,1Y3J0@135624,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP JOKFNDED_00249 1396418.BATQ01000041_gene6309 5.8e-99 367.5 Verrucomicrobiae ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2ITH0@203494,46SDM@74201,COG0443@1,COG0443@2 NA|NA|NA O MreB/Mbl protein JOKFNDED_00251 1403819.BATR01000096_gene3117 1e-51 209.9 Verrucomicrobiae ytwF Bacteria 2IUCJ@203494,46VE6@74201,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain JOKFNDED_00252 240016.ABIZ01000001_gene1887 1.1e-76 293.5 Verrucomicrobiae pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITHZ@203494,46SK0@74201,COG1183@1,COG1183@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase JOKFNDED_00253 794903.OPIT5_15865 2e-81 308.9 Opitutae Bacteria 3K7C4@414999,46UZ1@74201,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM short-chain dehydrogenase reductase SDR JOKFNDED_00254 1396141.BATP01000001_gene5365 3e-96 358.6 Bacteria 3.6.4.6 ko:K06027 ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962 ko00000,ko00001,ko01000,ko04131 1.F.1.1 Bacteria COG0464@1,COG0464@2 NA|NA|NA O ATPase activity JOKFNDED_00258 1396141.BATP01000032_gene4392 2.9e-23 115.2 Verrucomicrobiae Bacteria 2DGAX@1,2IW8D@203494,2ZV7P@2,46WTW@74201 NA|NA|NA S Heavy-metal resistance JOKFNDED_00259 1396141.BATP01000024_gene846 5.3e-43 181.0 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IUMN@203494,46VAA@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_00260 382464.ABSI01000005_gene974 1.1e-18 101.3 Verrucomicrobiae Bacteria 2IW13@203494,46WHQ@74201,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_00261 1396141.BATP01000024_gene848 8.6e-211 740.0 Verrucomicrobiae ko:K07798 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 Bacteria 2IUGZ@203494,46SVD@74201,COG0845@1,COG0845@2 NA|NA|NA M Protein of unknown function (DUF3347) JOKFNDED_00262 1396141.BATP01000024_gene849 0.0 1855.9 Verrucomicrobia ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.4 Bacteria 46SJ1@74201,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family JOKFNDED_00264 1123070.KB899257_gene2284 2.4e-71 276.2 Verrucomicrobiae rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU4U@203494,46SVX@74201,COG0036@1,COG0036@2 NA|NA|NA G Ribulose-phosphate 3 epimerase family JOKFNDED_00265 240016.ABIZ01000001_gene5218 6.3e-116 424.5 Verrucomicrobiae ko:K07577 ko00000 Bacteria 2ITW2@203494,46SQ0@74201,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain JOKFNDED_00266 935863.AWZR01000007_gene223 2.7e-108 399.1 Xanthomonadales yeiM ko:K03317 ko00000 2.A.41 Bacteria 1MXXX@1224,1RMBX@1236,1X3AE@135614,COG1972@1,COG1972@2 NA|NA|NA F Na dependent nucleoside transporter JOKFNDED_00267 1123242.JH636434_gene4069 2.1e-59 235.7 Planctomycetes Bacteria 2IX7B@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_00269 240016.ABIZ01000001_gene4784 1.5e-183 649.0 Verrucomicrobiae nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IU02@203494,46SA0@74201,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient JOKFNDED_00270 1201288.M900_1007 4.4e-11 73.9 Deltaproteobacteria Bacteria 1P7A9@1224,2ESM6@1,2WXY5@28221,33K5R@2,4326F@68525 NA|NA|NA S Protein of unknown function (DUF1232) JOKFNDED_00274 89187.ISM_16475 4.6e-24 117.5 Alphaproteobacteria Bacteria 1RAWV@1224,2C2XI@1,2U5X3@28211,30D1S@2 NA|NA|NA JOKFNDED_00275 756272.Plabr_4219 4.2e-111 407.9 Bacteria Bacteria COG3712@1,COG3712@2 NA|NA|NA PT iron ion homeostasis JOKFNDED_00278 1403819.BATR01000084_gene2439 1.2e-106 393.7 Verrucomicrobiae Bacteria 2IVAN@203494,46U6Q@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_00279 240016.ABIZ01000001_gene1321 4.9e-18 99.0 Verrucomicrobia Bacteria 2E19R@1,32WPZ@2,46VE3@74201 NA|NA|NA JOKFNDED_00280 313628.LNTAR_07444 6.2e-36 157.5 Bacteria rfaY ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_00281 1207063.P24_16011 1.2e-10 73.9 Rhodospirillales Bacteria 1NGKR@1224,2JZJ1@204441,2UGKC@28211,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain JOKFNDED_00282 1403819.BATR01000031_gene982 1.9e-123 449.1 Verrucomicrobiae rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2ITGQ@203494,46SBD@74201,COG0820@1,COG0820@2 NA|NA|NA J Elongator protein 3, MiaB family, Radical SAM JOKFNDED_00284 1123258.AQXZ01000015_gene4625 2.9e-27 128.3 Nocardiaceae hit-1 ko:K02503 ko00000,ko04147 Bacteria 2INIP@201174,4G0M4@85025,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding JOKFNDED_00286 382464.ABSI01000014_gene1435 6.7e-150 537.3 Verrucomicrobia pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 46SBC@74201,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane JOKFNDED_00287 382464.ABSI01000014_gene1434 5.1e-28 130.2 Verrucomicrobia pntA-2 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 46T7S@74201,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch JOKFNDED_00288 382464.ABSI01000014_gene1433 4.6e-120 438.0 Verrucomicrobia pntA GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 46SFW@74201,COG3288@1,COG3288@2 NA|NA|NA C Alanine dehydrogenase/PNT, N-terminal domain JOKFNDED_00289 1403819.BATR01000041_gene1216 6.9e-38 164.9 Verrucomicrobiae ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IVRT@203494,46VYX@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_00290 395964.KE386496_gene2447 1.7e-42 179.1 Alphaproteobacteria ymaD Bacteria 1RI5C@1224,2U99X@28211,COG1764@1,COG1764@2 NA|NA|NA O redox protein regulator of disulfide bond formation JOKFNDED_00291 1396418.BATQ01000101_gene5447 2.3e-51 208.4 Verrucomicrobiae phyH Bacteria 2DHFW@1,2IVW8@203494,2ZZKM@2,46SNY@74201 NA|NA|NA JOKFNDED_00292 1396141.BATP01000016_gene2819 9e-167 593.2 Verrucomicrobiae fabV GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IU0P@203494,46S92@74201,COG3007@1,COG3007@2 NA|NA|NA I NAD(P)H binding domain of trans-2-enoyl-CoA reductase JOKFNDED_00293 1396418.BATQ01000141_gene3394 1.2e-26 126.7 Bacteria Bacteria COG1376@1,COG1376@2 NA|NA|NA D ErfK ybiS ycfS ynhG family protein JOKFNDED_00294 886293.Sinac_6868 7.1e-22 111.7 Planctomycetes Bacteria 2J51K@203682,COG2133@1,COG2133@2 NA|NA|NA G Methane oxygenase PmoA JOKFNDED_00295 1403819.BATR01000112_gene3876 6.2e-67 261.2 Verrucomicrobiae Bacteria 2IUNM@203494,46T96@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_00296 240016.ABIZ01000001_gene1914 7.6e-130 470.7 Verrucomicrobiae hflX ko:K03665 ko00000,ko03009 Bacteria 2IU26@203494,46SP4@74201,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis JOKFNDED_00297 1123070.KB899260_gene2048 7.7e-28 132.1 Verrucomicrobiae 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 2ITWV@203494,46SBB@74201,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA D Chain length determinant protein JOKFNDED_00298 1396418.BATQ01000008_gene1512 2.4e-80 305.1 Verrucomicrobiae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2ITWB@203494,46SIZ@74201,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage JOKFNDED_00299 1403819.BATR01000102_gene3423 1.7e-99 369.4 Verrucomicrobia 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 GT28 Bacteria 46U6B@74201,COG1413@1,COG1413@2,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase JOKFNDED_00300 929556.Solca_0662 1e-18 99.8 Bacteria Bacteria COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity JOKFNDED_00301 240016.ABIZ01000001_gene4032 1.5e-247 862.1 Verrucomicrobiae Bacteria 2IWJZ@203494,46UAS@74201,COG0654@1,COG0654@2 NA|NA|NA CH FAD dependent oxidoreductase JOKFNDED_00302 1123242.JH636436_gene668 1.5e-07 62.8 Planctomycetes Bacteria 2EQFW@1,2J1JM@203682,33I1X@2 NA|NA|NA JOKFNDED_00303 1403819.BATR01000021_gene742 1.5e-153 549.3 Verrucomicrobia neu 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 46SHF@74201,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_00304 1396418.BATQ01000058_gene90 8.2e-118 429.9 Verrucomicrobia MA20_26380 Bacteria 46SB3@74201,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA JOKFNDED_00305 1403819.BATR01000164_gene5582 3.4e-56 225.7 Verrucomicrobiae ko:K02529 ko00000,ko03000 Bacteria 2IUF7@203494,46U1N@74201,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain JOKFNDED_00306 886293.Sinac_2107 3.9e-109 401.4 Planctomycetes nanA 4.1.3.3,4.3.3.7 ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01811,R10147 RC00159,RC00600,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYE2@203682,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthase N-acetylneuraminate lyase JOKFNDED_00308 525897.Dbac_2880 5.8e-32 143.7 Deltaproteobacteria ko:K06929 ko00000 Bacteria 1PUW7@1224,2WPHZ@28221,42T5D@68525,COG1832@1,COG1832@2 NA|NA|NA S CoA binding domain JOKFNDED_00309 1396418.BATQ01000171_gene2897 1.8e-189 669.1 Bacteria Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_00310 497964.CfE428DRAFT_6306 2.3e-128 465.3 Verrucomicrobia ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 46W7Q@74201,COG1879@1,COG1879@2 NA|NA|NA G PFAM periplasmic binding protein LacI transcriptional regulator JOKFNDED_00311 497964.CfE428DRAFT_6304 1.4e-123 449.9 Verrucomicrobia ko:K10440 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 46V1Z@74201,COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family JOKFNDED_00313 794903.OPIT5_13610 7.6e-77 295.0 Bacteria Bacteria COG2831@1,COG2831@2 NA|NA|NA U hemolysin activation secretion protein JOKFNDED_00314 177439.DP1520 8.1e-83 317.0 Desulfobacterales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1MXIP@1224,2MNJ9@213118,2WQ54@28221,42TFA@68525,COG3210@1,COG3210@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_00316 452637.Oter_4565 1.2e-113 417.5 Opitutae 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 3K73R@414999,46V2N@74201,COG2114@1,COG2114@2,COG4252@1,COG4252@2 NA|NA|NA T PFAM adenylyl cyclase class-3 4 guanylyl cyclase JOKFNDED_00317 1403819.BATR01000107_gene3650 1.9e-200 705.7 Verrucomicrobiae glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 2ITM7@203494,46USD@74201,COG0664@1,COG0664@2,COG2066@1,COG2066@2 NA|NA|NA ET Glutaminase JOKFNDED_00318 344747.PM8797T_16143 5.7e-69 268.9 Bacteria 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria COG4409@1,COG4409@2 NA|NA|NA G exo-alpha-(2->6)-sialidase activity JOKFNDED_00319 1403819.BATR01000124_gene4372 6.6e-44 183.3 Verrucomicrobia Bacteria 28SYW@1,2ZF89@2,46WJW@74201 NA|NA|NA JOKFNDED_00320 1177928.TH2_10154 2.3e-83 315.8 Rhodospirillales glpQ GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 Bacteria 1MVWZ@1224,2JT8B@204441,2TV4M@28211,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family JOKFNDED_00321 1396418.BATQ01000049_gene398 1.2e-79 303.1 Verrucomicrobiae ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IUFT@203494,46SNC@74201,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family JOKFNDED_00323 1268303.RHODMAR_3505 1.4e-57 229.9 Actinobacteria Bacteria 2B7HE@1,2H4D0@201174,320ME@2 NA|NA|NA JOKFNDED_00324 290397.Adeh_3442 2.8e-112 412.1 Deltaproteobacteria ydiP GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008168,GO:0009307,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044728,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:0099046,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1MV9H@1224,2WWDC@28221,42NPS@68525,COG0270@1,COG0270@2 NA|NA|NA H C-5 cytosine-specific DNA methylase JOKFNDED_00325 1304275.C41B8_04161 2.2e-64 253.4 Gammaproteobacteria ycbB ko:K21470 ko00000,ko01002,ko01011 Bacteria 1MV14@1224,1RQR7@1236,COG2989@1,COG2989@2 NA|NA|NA M protein conserved in bacteria JOKFNDED_00327 1353529.M899_2347 2.6e-34 152.5 Proteobacteria Bacteria 1NES4@1224,2CIHU@1,338F9@2 NA|NA|NA JOKFNDED_00328 1123070.KB899253_gene1109 1.6e-159 569.7 Verrucomicrobiae dagA ko:K03310 ko00000 2.A.25 Bacteria 2IU9Z@203494,46TWQ@74201,COG1115@1,COG1115@2 NA|NA|NA E Sodium:alanine symporter family JOKFNDED_00329 1123070.KB899249_gene330 1.3e-73 283.1 Verrucomicrobiae sdhC ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 2CAZH@1,2IUAR@203494,2Z7RU@2,46SY1@74201 NA|NA|NA JOKFNDED_00330 1396141.BATP01000060_gene4579 2.8e-311 1074.7 Verrucomicrobiae sdhA 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITUA@203494,46S7D@74201,COG1053@1,COG1053@2 NA|NA|NA C Fumarate reductase flavoprotein C-term JOKFNDED_00331 1123070.KB899247_gene1522 5.2e-112 410.6 Verrucomicrobiae sdhB 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2395 Bacteria 2ITQJ@203494,46S82@74201,COG0479@1,COG0479@2 NA|NA|NA C 2Fe-2S iron-sulfur cluster binding domain JOKFNDED_00332 1123504.JQKD01000031_gene4578 2.3e-12 79.0 Comamonadaceae Bacteria 1NI1P@1224,2EGFZ@1,2VY2Y@28216,33A7Y@2,4AFVJ@80864 NA|NA|NA S Ribosomal protein L7/L12 C-terminal domain JOKFNDED_00333 240016.ABIZ01000001_gene4742 6.1e-212 743.8 Verrucomicrobia ko:K09729 ko00000 Bacteria 46TEA@74201,COG0142@1,COG0142@2,COG1852@1,COG1852@2 NA|NA|NA H Protein of unknown function DUF116 JOKFNDED_00335 497964.CfE428DRAFT_2276 3.7e-151 541.6 Bacteria ko:K06937 ko00000,ko01000 Bacteria COG1964@1,COG1964@2 NA|NA|NA Q Radical SAM superfamily JOKFNDED_00336 1403819.BATR01000083_gene2422 1.2e-49 203.4 Verrucomicrobiae ko:K13292 ko00000,ko01000 Bacteria 2IVRW@203494,46V9N@74201,COG0682@1,COG0682@2 NA|NA|NA M Prolipoprotein diacylglyceryl transferase JOKFNDED_00339 1403819.BATR01000150_gene5079 7.9e-14 83.2 Bacteria Bacteria COG2220@1,COG2220@2 NA|NA|NA S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity JOKFNDED_00340 1396418.BATQ01000186_gene2165 1.3e-133 482.6 Verrucomicrobiae ko:K03086 ko00000,ko03021 Bacteria 2IU0G@203494,46SJ8@74201,COG0568@1,COG0568@2 NA|NA|NA K Sigma-70 region 3 JOKFNDED_00341 344747.PM8797T_08324 4.1e-151 541.6 Planctomycetes Bacteria 2IWX1@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00342 240016.ABIZ01000001_gene5457 2.9e-184 651.7 Verrucomicrobiae 3.1.6.13 ko:K01136 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00078 R07812,R07821 ko00000,ko00001,ko00002,ko01000 Bacteria 2IV5A@203494,46U45@74201,COG3119@1,COG3119@2 NA|NA|NA P Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_00343 314278.NB231_16448 3e-08 64.3 Bacteria GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 Bacteria 2DSUP@1,33HGU@2 NA|NA|NA JOKFNDED_00344 583355.Caka_0699 2.2e-46 191.8 Bacteria GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 ko:K07064 ko00000 Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_00345 521674.Plim_2382 3.3e-192 677.9 Planctomycetes Bacteria 2IXP1@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00346 530564.Psta_0278 2.2e-190 671.8 Planctomycetes Bacteria 2IYNZ@203682,COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase A JOKFNDED_00347 1403819.BATR01000094_gene3003 1.7e-28 132.9 Bacteria Bacteria COG1376@1,COG1376@2 NA|NA|NA D ErfK ybiS ycfS ynhG family protein JOKFNDED_00348 497964.CfE428DRAFT_6006 5.9e-111 407.5 Verrucomicrobia Bacteria 46TKX@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_00349 344747.PM8797T_16018 3.4e-109 401.7 Bacteria 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 GH32 Bacteria COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family JOKFNDED_00350 344747.PM8797T_25366 1.6e-114 419.9 Planctomycetes Bacteria 2IYHX@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins JOKFNDED_00352 240016.ABIZ01000001_gene2035 8.6e-93 347.1 Verrucomicrobia Bacteria 28HY6@1,2Z83M@2,46V0G@74201 NA|NA|NA S Domain of unknown function (DUF4886) JOKFNDED_00353 1123508.JH636448_gene7562 5.3e-132 477.6 Planctomycetes 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYTH@203682,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller JOKFNDED_00354 530564.Psta_1924 1.6e-161 575.9 Planctomycetes Bacteria 2J3KJ@203682,COG3408@1,COG3408@2 NA|NA|NA G Alkaline and neutral invertase JOKFNDED_00355 935848.JAEN01000005_gene3678 8e-169 600.1 Paracoccus sps GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 ko:K00696,ko:K13058 ko00500,ko01100,map00500,map01100 R00766,R08947 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 GT4 Bacteria 1MWVX@1224,2PUEG@265,2U223@28211,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain JOKFNDED_00356 935848.JAEN01000005_gene3677 5.6e-42 177.9 Alphaproteobacteria sps GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,3.1.3.24,3.1.3.79 ko:K00696,ko:K07024,ko:K13086 ko00500,ko01100,map00500,map01100 R00766,R00805,R06211,R08982 RC00005,RC00017,RC00028,RC02748 ko00000,ko00001,ko01000 GT4 iJN678.slr0953 Bacteria 1PD4E@1224,2UH8B@28211,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase JOKFNDED_00359 1396418.BATQ01000127_gene2556 4.3e-75 288.1 Verrucomicrobiae Bacteria 2IVTQ@203494,46VJM@74201,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation JOKFNDED_00360 443218.AS9A_4476 2e-23 116.3 Mycobacteriaceae Bacteria 23F5Y@1762,2I2VP@201174,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family JOKFNDED_00361 240016.ABIZ01000001_gene2352 2.8e-235 821.6 Verrucomicrobia 1.8.1.9,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K00384,ko:K03388 ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R02016,R03596,R04540,R09372,R11928,R11931,R11943,R11944 RC00011,RC00013,RC02518,RC02873 ko00000,ko00001,ko00002,ko01000 Bacteria 46U3S@74201,COG2072@1,COG2072@2 NA|NA|NA P FAD dependent oxidoreductase JOKFNDED_00362 240016.ABIZ01000001_gene3843 2.2e-40 171.4 Verrucomicrobiae phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 2IUJP@203494,46VQ6@74201,COG2824@1,COG2824@2 NA|NA|NA P PhnA domain JOKFNDED_00363 497964.CfE428DRAFT_0868 2.6e-56 225.3 Bacteria paiB ko:K07734 ko00000,ko03000 Bacteria COG2808@1,COG2808@2 NA|NA|NA K Putative FMN-binding domain JOKFNDED_00364 1123242.JH636434_gene5111 2.5e-126 459.1 Planctomycetes Bacteria 2IWVG@203682,COG2133@1,COG2133@2 NA|NA|NA G pyrroloquinoline quinone binding JOKFNDED_00365 886293.Sinac_2423 1.1e-41 176.0 Planctomycetes ko:K03824 ko00000,ko01000 Bacteria 2IZSX@203682,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) domain JOKFNDED_00366 1278073.MYSTI_06515 2.4e-70 272.3 Myxococcales ada 2.1.1.63 ko:K00567,ko:K10778 ko00000,ko01000,ko03000,ko03400 Bacteria 1N2YQ@1224,2WRJ0@28221,2YZ2C@29,42MQN@68525,COG0350@1,COG0350@2,COG2207@1,COG2207@2 NA|NA|NA K 6-O-methylguanine DNA methyltransferase, DNA binding domain JOKFNDED_00367 1121033.AUCF01000001_gene2030 5.8e-44 184.9 Rhodospirillales Bacteria 1RCED@1224,2JRZ1@204441,2U66Q@28211,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family JOKFNDED_00369 1123070.KB899255_gene1352 2.7e-16 93.6 Verrucomicrobiae Bacteria 2EZMG@1,2IU6Q@203494,33SSM@2,46UUT@74201 NA|NA|NA JOKFNDED_00370 1033732.CAHI01000003_gene2377 5.9e-41 175.6 Bacteroidia Bacteria 2FU0J@200643,4NHIP@976,COG5434@1,COG5434@2 NA|NA|NA G Pectate lyase superfamily protein JOKFNDED_00371 1123248.KB893328_gene904 7.1e-08 63.9 Bacteria ko:K09940 ko00000 Bacteria COG3296@1,COG3296@2 NA|NA|NA S Domain of unknown function (DUF4870) JOKFNDED_00375 1396418.BATQ01000079_gene794 1.2e-242 845.5 Verrucomicrobia Bacteria 46TS2@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00376 240016.ABIZ01000001_gene3527 2.1e-167 596.3 Verrucomicrobia Bacteria 46TQT@74201,COG2319@1,COG2319@2 NA|NA|NA S WD40 repeats JOKFNDED_00377 1396418.BATQ01000079_gene797 1.1e-266 926.0 Verrucomicrobia Bacteria 46TED@74201,COG3064@1,COG3064@2 NA|NA|NA M Membrane JOKFNDED_00378 1403819.BATR01000147_gene5044 1.4e-104 386.0 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46TTH@74201,COG5492@1,COG5492@2 NA|NA|NA N Protein of unknown function (DUF1549) JOKFNDED_00379 864702.OsccyDRAFT_3741 2.7e-27 129.0 Oscillatoriales hetI 2.7.8.7 ko:K00997,ko:K06133 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000 Bacteria 1G5GA@1117,1HAPE@1150,COG2091@1,COG2091@2 NA|NA|NA H Belongs to the P-Pant transferase superfamily JOKFNDED_00382 1469607.KK073769_gene5864 3.2e-32 144.4 Nostocales Bacteria 1G7XW@1117,1HSKM@1161,COG4634@1,COG4634@2 NA|NA|NA S Mut7-C RNAse domain JOKFNDED_00383 756067.MicvaDRAFT_5379 2.7e-20 104.8 Oscillatoriales 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1GDYI@1117,1HFJV@1150,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) JOKFNDED_00384 497964.CfE428DRAFT_1081 1.2e-30 139.4 Verrucomicrobia Bacteria 46VNS@74201,COG2050@1,COG2050@2 NA|NA|NA Q Domain of unknown function (DUF4442) JOKFNDED_00387 1434325.AZQN01000002_gene1136 1.8e-116 426.8 Cytophagia Bacteria 47NF5@768503,4NEZJ@976,COG1413@1,COG1413@2,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_00388 1403819.BATR01000004_gene125 2.8e-94 353.2 Verrucomicrobiae Bacteria 2IVW2@203494,46UJA@74201,COG1506@1,COG1506@2 NA|NA|NA E Acetyl xylan esterase (AXE1) JOKFNDED_00389 1123060.JONP01000007_gene5039 7.2e-105 387.5 Rhodospirillales rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 1MUYK@1224,2JQBS@204441,2TQT3@28211,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs JOKFNDED_00392 1396141.BATP01000005_gene6043 2.1e-32 145.2 Verrucomicrobiae Bacteria 2CH3Z@1,2IUSD@203494,32RP9@2,46ZH2@74201 NA|NA|NA S Protein of unknown function (DUF2721) JOKFNDED_00393 240016.ABIZ01000001_gene5853 2.8e-52 211.5 Verrucomicrobiae Bacteria 2IUHR@203494,46VBP@74201,COG2258@1,COG2258@2 NA|NA|NA S MOSC domain JOKFNDED_00394 1403819.BATR01000010_gene318 1.1e-220 772.7 Verrucomicrobiae proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2ITKS@203494,46SE3@74201,COG0442@1,COG0442@2 NA|NA|NA J Prolyl-tRNA synthetase, C-terminal JOKFNDED_00395 521674.Plim_3412 5.3e-40 171.4 Bacteria Bacteria 2EIRT@1,33CH6@2 NA|NA|NA JOKFNDED_00397 1396418.BATQ01000168_gene1798 3e-42 178.7 Verrucomicrobiae Bacteria 2ED0A@1,2IW39@203494,336X9@2,46TCE@74201 NA|NA|NA JOKFNDED_00398 331869.BAL199_28440 6.1e-84 317.8 unclassified Alphaproteobacteria hflK ko:K04088 M00742 ko00000,ko00002,ko01000 Bacteria 1MUM2@1224,2TRTP@28211,4BP7N@82117,COG0330@1,COG0330@2 NA|NA|NA O HflC and HflK could encode or regulate a protease JOKFNDED_00399 631362.Thi970DRAFT_04763 1.8e-102 379.4 Chromatiales hflC ko:K04087 M00742 ko00000,ko00002,ko01000 Bacteria 1MV7R@1224,1RMF2@1236,1X0ZR@135613,COG0330@1,COG0330@2 NA|NA|NA O HflC and HflK could regulate a protease JOKFNDED_00400 1403819.BATR01000114_gene3987 4.3e-83 316.2 Bacteria Bacteria COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase JOKFNDED_00401 1396418.BATQ01000091_gene5778 3.7e-197 694.9 Verrucomicrobiae speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iIT341.HP0422,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Bacteria 2ITMU@203494,46S4T@74201,COG1166@1,COG1166@2 NA|NA|NA E Pyridoxal-dependent decarboxylase, pyridoxal binding domain JOKFNDED_00403 240016.ABIZ01000001_gene3903 4.6e-29 134.4 Verrucomicrobiae Bacteria 2IW16@203494,46W0N@74201,COG3241@1,COG3241@2 NA|NA|NA C Copper binding proteins, plastocyanin/azurin family JOKFNDED_00404 1142394.PSMK_20320 1.1e-66 260.8 Bacteria Bacteria 2C3QV@1,2Z7YP@2 NA|NA|NA JOKFNDED_00405 452637.Oter_0906 3.7e-35 155.2 Opitutae ko:K01420,ko:K21563 ko00000,ko03000 Bacteria 3K7W4@414999,46VK1@74201,COG0664@1,COG0664@2 NA|NA|NA K Crp Fnr family JOKFNDED_00406 264462.Bd2601 1.1e-46 193.7 delta/epsilon subdivisions norC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 Bacteria 1RDSI@1224,42WEW@68525,COG2010@1,COG2010@2 NA|NA|NA C cytochrome c JOKFNDED_00407 264462.Bd2599 6.7e-198 696.8 Bdellovibrionales norB 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 1MVT1@1224,2MU96@213481,2WKTG@28221,42NBM@68525,COG3256@1,COG3256@2 NA|NA|NA C Cytochrome C and Quinol oxidase polypeptide I JOKFNDED_00408 395495.Lcho_1467 2.4e-80 305.4 unclassified Burkholderiales norQ ko:K03924,ko:K04748 R00294 RC02794 ko00000,ko01000 3.D.4.10 Bacteria 1KJZ6@119065,1MXIW@1224,2VHWI@28216,COG0714@1,COG0714@2 NA|NA|NA S CbbQ NirQ NorQ JOKFNDED_00409 643867.Ftrac_2742 1.2e-66 261.2 Cytophagia ko:K02448 R00294 RC02794 ko00000 3.D.4.10 Bacteria 47U2R@768503,4NIHR@976,COG4548@1,COG4548@2 NA|NA|NA P von Willebrand factor (vWF) type A domain JOKFNDED_00410 670307.HYPDE_35983 2e-11 75.1 Alphaproteobacteria Bacteria 1RHJ3@1224,2U9XS@28211,COG4274@1,COG4274@2 NA|NA|NA S GYD domain JOKFNDED_00411 497964.CfE428DRAFT_2739 1e-49 203.0 Bacteria ko:K06886 ko00000 Bacteria COG2346@1,COG2346@2 NA|NA|NA O COG2346, Truncated hemoglobins JOKFNDED_00412 497964.CfE428DRAFT_3241 1.2e-58 234.2 Bacteria Bacteria COG1262@1,COG1262@2 NA|NA|NA T PFAM Formylglycine-generating sulfatase enzyme JOKFNDED_00413 264462.Bd2608 9.9e-177 626.7 Proteobacteria nirK 1.7.2.1 ko:K00368,ko:K12263 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV74@1224,COG2010@1,COG2010@2,COG2132@1,COG2132@2 NA|NA|NA Q Nitrite reductase JOKFNDED_00414 720554.Clocl_3102 7.5e-96 357.5 Ruminococcaceae 4.1.3.39 ko:K01666 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750 RC00307,RC00371 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 1TS0A@1239,247MU@186801,3WHBT@541000,COG0119@1,COG0119@2 NA|NA|NA E HMGL-like JOKFNDED_00415 1123248.KB893337_gene2370 1.3e-53 216.5 Bacteroidetes msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 4NMAJ@976,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine JOKFNDED_00417 234267.Acid_2265 6.2e-167 594.0 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00418 234267.Acid_2264 3.3e-156 558.5 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG5492@1,COG5492@2 NA|NA|NA N domain, Protein JOKFNDED_00419 595460.RRSWK_06278 4.5e-125 454.9 Planctomycetes 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 2J4SC@203682,COG0251@1,COG0251@2 NA|NA|NA J oxidation-reduction process JOKFNDED_00421 643867.Ftrac_2740 7.7e-34 150.6 Cytophagia ko:K02164 R00294 RC02794 ko00000 3.D.4.10 Bacteria 47S6P@768503,4NMCB@976,COG1845@1,COG1845@2 NA|NA|NA C Cytochrome c oxidase subunit III JOKFNDED_00422 234267.Acid_2266 4.1e-125 455.7 Bacteria Bacteria COG2319@1,COG2319@2 NA|NA|NA S anaphase-promoting complex binding JOKFNDED_00423 234267.Acid_2265 2.5e-144 518.8 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00424 234267.Acid_2264 2.4e-165 589.0 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG5492@1,COG5492@2 NA|NA|NA N domain, Protein JOKFNDED_00425 1303518.CCALI_00076 1.5e-51 209.9 Bacteria ytfE GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564 ko:K07322 ko00000 iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820 Bacteria COG2846@1,COG2846@2 NA|NA|NA D Di-iron-containing protein involved in the repair of iron-sulfur clusters JOKFNDED_00426 583355.Caka_0069 2.6e-28 131.7 Verrucomicrobia Bacteria 46VWM@74201,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator JOKFNDED_00427 595460.RRSWK_06483 4.3e-81 308.5 Planctomycetes acrA ko:K02005 ko00000 Bacteria 2IYTR@203682,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_00428 595460.RRSWK_06482 2.1e-134 485.7 Bacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity JOKFNDED_00429 595460.RRSWK_06481 1.6e-78 299.3 Bacteria hrtA ko:K02003,ko:K09814 ko02010,map02010 M00257,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria COG1136@1,COG1136@2 NA|NA|NA V lipoprotein transporter activity JOKFNDED_00430 497964.CfE428DRAFT_5882 1.4e-42 180.6 Verrucomicrobia ko:K07234 ko00000 Bacteria 46VTH@74201,COG3213@1,COG3213@2 NA|NA|NA P NnrS protein JOKFNDED_00431 349741.Amuc_0791 1.7e-141 509.2 Verrucomicrobia nirJ ko:K22226 ko00000 Bacteria 46T4P@74201,COG0535@1,COG0535@2 NA|NA|NA C SMART Elongator protein 3 MiaB NifB JOKFNDED_00432 349741.Amuc_0792 1.6e-117 429.5 Verrucomicrobia ko:K22227 ko00000 Bacteria 46T4P@74201,COG0535@1,COG0535@2 NA|NA|NA C SMART Elongator protein 3 MiaB NifB JOKFNDED_00433 452637.Oter_0306 7.1e-69 267.3 Bacteria Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 JOKFNDED_00435 595460.RRSWK_02044 8.8e-59 235.0 Bacteria wgeF Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 JOKFNDED_00436 1396418.BATQ01000044_gene6446 6.8e-26 124.0 Bacteria Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis JOKFNDED_00437 1238450.VIBNISOn1_450065 5.3e-82 311.2 Bacteria Bacteria COG2128@1,COG2128@2 NA|NA|NA S hydroperoxide reductase activity JOKFNDED_00438 452637.Oter_3779 1.2e-37 163.3 Opitutae sigV ko:K03088 ko00000,ko03021 Bacteria 3K9NK@414999,46VX9@74201,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family JOKFNDED_00439 452637.Oter_0300 4.4e-21 108.6 Bacteria Bacteria COG5662@1,COG5662@2 NA|NA|NA K AntiSigma factor JOKFNDED_00440 1415755.JQLV01000002_gene583 8.6e-23 114.0 Oceanospirillales sigX ko:K03088 ko00000,ko03021 Bacteria 1RHKM@1224,1S48U@1236,1XK4H@135619,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_00441 404589.Anae109_0599 1.5e-43 183.0 Proteobacteria pgl 3.1.1.31,5.3.1.9 ko:K01057,ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00006,M00008,M00114 R02035,R02739,R02740,R03321 RC00376,RC00537,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1R5K6@1224,COG0363@1,COG0363@2 NA|NA|NA G 6-phosphogluconolactonase JOKFNDED_00442 595537.Varpa_2251 6.2e-79 301.2 Comamonadaceae Bacteria 1R4MG@1224,2VK4V@28216,4ADCB@80864,COG2207@1,COG2207@2 NA|NA|NA K transcriptional regulator, AraC JOKFNDED_00443 399795.CtesDRAFT_PD3156 6.9e-183 647.1 Comamonadaceae 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1MU6G@1224,2VH80@28216,4ACR6@80864,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain JOKFNDED_00444 688245.CtCNB1_1714 1.3e-71 276.2 Comamonadaceae Bacteria 1MU8C@1224,2VM0D@28216,4AA5V@80864,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family JOKFNDED_00445 240016.ABIZ01000001_gene5370 3.6e-20 104.4 Verrucomicrobiae Bacteria 2IWCY@203494,46XQ5@74201,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor JOKFNDED_00446 1403819.BATR01000174_gene5901 9.7e-29 134.8 Verrucomicrobiae Bacteria 2IVS7@203494,46XFM@74201,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV JOKFNDED_00448 706587.Desti_3519 9e-42 177.6 Syntrophobacterales znuA 1.6.5.3 ko:K00341,ko:K02077,ko:K09815 ko00190,ko01100,ko02010,map00190,map01100,map02010 M00144,M00242,M00244 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.D.1 Bacteria 1MVW9@1224,2MRPD@213462,2WJYG@28221,42MBX@68525,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family JOKFNDED_00449 933262.AXAM01000001_gene416 4.8e-55 221.5 Desulfobacterales znuC ko:K09817 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 1MUDW@1224,2MHMM@213118,2WKMZ@28221,42NI8@68525,COG1121@1,COG1121@2 NA|NA|NA P PFAM ABC transporter JOKFNDED_00450 644282.Deba_0604 1.4e-57 229.9 Deltaproteobacteria znuB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K02075,ko:K09816,ko:K19976 ko02010,map02010 M00242,M00244,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1MVC2@1224,2WJAM@28221,42MYM@68525,COG1108@1,COG1108@2 NA|NA|NA P PFAM ABC-3 protein JOKFNDED_00451 441620.Mpop_5402 1.3e-154 553.1 Methylobacteriaceae MA20_28420 Bacteria 1JS3J@119045,1MVK3@1224,2TT84@28211,COG0397@1,COG0397@2 NA|NA|NA S Belongs to the UPF0061 (SELO) family JOKFNDED_00452 1403819.BATR01000176_gene5944 1e-60 240.7 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_00453 1123070.KB899270_gene2364 2.8e-149 535.0 Verrucomicrobiae citZ 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2ITKN@203494,46SBV@74201,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain JOKFNDED_00454 349741.Amuc_1712 3.6e-25 120.6 Verrucomicrobiae sucD GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iYO844.BSU16100 Bacteria 2ITVZ@203494,46TRM@74201,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit JOKFNDED_00463 313628.LNTAR_10901 6.3e-125 454.9 Bacteria ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria COG2010@1,COG2010@2,COG2319@1,COG2319@2 NA|NA|NA S anaphase-promoting complex binding JOKFNDED_00464 1403819.BATR01000045_gene1313 2.6e-135 488.8 Verrucomicrobiae Bacteria 2IU14@203494,46U0B@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00465 907348.TresaDRAFT_0122 4.1e-14 85.9 Spirochaetes rlpA ko:K03642 ko00000 Bacteria 2J8E5@203691,COG0797@1,COG0797@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides JOKFNDED_00466 1107311.Q767_14510 1.6e-62 246.1 Flavobacterium yugP ko:K06973 ko00000 Bacteria 1HXAU@117743,2NSBY@237,4NDWG@976,COG2738@1,COG2738@2 NA|NA|NA S membrane JOKFNDED_00467 497964.CfE428DRAFT_5033 2e-141 508.8 Verrucomicrobia Bacteria 46UFN@74201,COG1541@1,COG1541@2 NA|NA|NA H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) JOKFNDED_00468 314230.DSM3645_18936 7.7e-150 537.3 Planctomycetes ko:K03307 ko00000 2.A.21 Bacteria 2IY5N@203682,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family JOKFNDED_00469 344747.PM8797T_12768 2.4e-09 67.8 Planctomycetes Bacteria 2EJH6@1,2J1HK@203682,33D83@2 NA|NA|NA S Protein of unknown function (DUF3311) JOKFNDED_00470 497964.CfE428DRAFT_5031 1.6e-132 479.9 Verrucomicrobia Bacteria 46U89@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_00471 1403819.BATR01000181_gene6057 6.1e-212 744.2 Verrucomicrobia Bacteria 46UUP@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_00472 1123070.KB899254_gene1225 6.1e-29 134.4 Verrucomicrobiae rfaY ko:K03088 ko00000,ko03021 Bacteria 2IVUN@203494,46XGG@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_00474 1403819.BATR01000118_gene4128 2.4e-60 238.8 Verrucomicrobiae Bacteria 2IUI1@203494,46U31@74201,COG2152@1,COG2152@2 NA|NA|NA G Domain of Unknown Function (DUF1080) JOKFNDED_00475 1403819.BATR01000002_gene28 2.2e-89 336.3 Verrucomicrobiae tlyC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 2IVE3@203494,46U7J@74201,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain JOKFNDED_00476 497964.CfE428DRAFT_3022 7e-22 110.2 Verrucomicrobia ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 46T86@74201,COG2363@1,COG2363@2 NA|NA|NA S Protein of unknown function (DUF423) JOKFNDED_00477 497964.CfE428DRAFT_5419 2.5e-74 285.4 Bacteria Bacteria COG5507@1,COG5507@2 NA|NA|NA JOKFNDED_00478 497964.CfE428DRAFT_3783 1.7e-46 192.6 Bacteria MA20_24580 Bacteria COG0431@1,COG0431@2 NA|NA|NA S FMN reductase (NADPH) activity JOKFNDED_00479 240016.ABIZ01000001_gene1564 3.2e-25 121.7 Bacteria Bacteria COG4886@1,COG4886@2 NA|NA|NA S regulation of response to stimulus JOKFNDED_00480 926549.KI421517_gene3343 5.4e-139 501.1 Cytophagia Bacteria 47N82@768503,4PJFT@976,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system JOKFNDED_00481 1403819.BATR01000191_gene6545 9.5e-177 626.7 Verrucomicrobiae 3.1.1.53 ko:K05970,ko:K09992 ko00000,ko01000 Bacteria 2ITNS@203494,46UXH@74201,COG2755@1,COG2755@2,COG3828@1,COG3828@2 NA|NA|NA E Carbohydrate esterase, sialic acid-specific acetylesterase JOKFNDED_00482 1403819.BATR01000010_gene360 3.7e-19 102.8 Verrucomicrobiae Bacteria 293V7@1,2IW1J@203494,2ZRAE@2,46WWA@74201 NA|NA|NA JOKFNDED_00485 313628.LNTAR_17353 4.1e-147 528.9 Bacteria pstC ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria COG4590@1,COG4590@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component JOKFNDED_00486 903818.KI912268_gene983 2.2e-108 399.1 Acidobacteria pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 3Y5DC@57723,COG0226@1,COG0226@2 NA|NA|NA P PBP superfamily domain JOKFNDED_00487 240016.ABIZ01000001_gene1537 1.5e-157 562.8 Verrucomicrobiae Bacteria 2IU49@203494,46S77@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_00489 1403819.BATR01000120_gene4245 2.4e-222 778.5 Verrucomicrobiae ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2ITPE@203494,46SEB@74201,COG0178@1,COG0178@2 NA|NA|NA L ATPases associated with a variety of cellular activities JOKFNDED_00490 1123059.KB823013_gene607 1.2e-123 450.7 Hyphomonadaceae dnaQ 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1QUVW@1224,2TSZS@28211,43ZJG@69657,COG2176@1,COG2176@2 NA|NA|NA L VRR_NUC JOKFNDED_00492 1121904.ARBP01000004_gene1126 1.9e-108 399.4 Bacteroidetes btaA ko:K13622 ko00564,map00564 R09072 RC00021,RC01091 ko00000,ko00001 Bacteria 4NWSD@976,COG5379@1,COG5379@2 NA|NA|NA I Protein of unknown function (DUF3419) JOKFNDED_00493 497964.CfE428DRAFT_6574 2.5e-59 235.3 Bacteria btaB ko:K13623 ko00564,map00564 R09073 RC00003,RC02308 ko00000,ko00001 Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase JOKFNDED_00494 1396418.BATQ01000125_gene5107 1.8e-228 798.5 Verrucomicrobia Bacteria 46TYG@74201,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_00495 497964.CfE428DRAFT_2314 0.0 1139.4 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_00496 1396141.BATP01000059_gene2600 6.9e-161 573.5 Verrucomicrobiae ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 2ITV8@203494,46S8D@74201,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner JOKFNDED_00497 1403819.BATR01000183_gene6323 7e-22 111.3 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_00498 497964.CfE428DRAFT_1820 5.4e-199 701.0 Verrucomicrobia Bacteria 46UJ0@74201,COG1506@1,COG1506@2 NA|NA|NA E Acetyl xylan esterase (AXE1) JOKFNDED_00499 344747.PM8797T_14549 8.5e-102 377.5 Planctomycetes Bacteria 2IX5S@203682,COG3356@1,COG3356@2 NA|NA|NA S Neutral/alkaline non-lysosomal ceramidase, N-terminal JOKFNDED_00500 1403819.BATR01000009_gene294 1.2e-166 594.3 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein JOKFNDED_00501 497964.CfE428DRAFT_6342 1e-94 354.8 Verrucomicrobia Bacteria 46TMJ@74201,COG3064@1,COG3064@2 NA|NA|NA M Peptidase M60-like family JOKFNDED_00502 1396141.BATP01000039_gene1291 1.9e-11 77.4 Verrucomicrobiae Bacteria 2IW3Y@203494,2ZTTB@2,46Z9U@74201,COG1450@1 NA|NA|NA NU protein transport across the cell outer membrane JOKFNDED_00503 497964.CfE428DRAFT_0121 3.3e-84 319.3 Verrucomicrobia Bacteria 46U9W@74201,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain JOKFNDED_00504 1396418.BATQ01000068_gene1653 1.8e-74 285.8 Verrucomicrobiae Bacteria 2IVDC@203494,46UVZ@74201,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_00506 1382306.JNIM01000001_gene4098 2.3e-22 111.7 Chloroflexi ko:K07171 ko00000,ko01000,ko02048 Bacteria 2G9EZ@200795,COG2337@1,COG2337@2 NA|NA|NA L PemK-like, MazF-like toxin of type II toxin-antitoxin system JOKFNDED_00507 1403819.BATR01000132_gene4688 6.3e-133 481.9 Verrucomicrobia Bacteria 2BMSD@1,32GBT@2,46VIR@74201 NA|NA|NA JOKFNDED_00508 344747.PM8797T_18644 6.5e-140 504.2 Planctomycetes 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IYM7@203682,COG0160@1,COG0160@2 NA|NA|NA E Aminotransferase class-III JOKFNDED_00509 344747.PM8797T_18639 4.2e-162 577.8 Planctomycetes gal GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.376,1.1.1.48 ko:K00035,ko:K13873 ko00052,ko00053,ko01100,map00052,map00053,map01100 R01094,R01097,R01757,R10787 RC00161,RC00187 ko00000,ko00001,ko01000 Bacteria 2IXXQ@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_00510 344747.PM8797T_18634 5e-40 171.4 Bacteria Bacteria COG1802@1,COG1802@2 NA|NA|NA K Transcriptional regulator JOKFNDED_00511 240016.ABIZ01000001_gene4119 5.2e-20 105.5 Verrucomicrobiae Bacteria 2IUKQ@203494,46WD6@74201,COG0724@1,COG0724@2 NA|NA|NA S RNA recognition motif JOKFNDED_00512 1396141.BATP01000007_gene5546 4e-32 144.4 Verrucomicrobiae Bacteria 2IUU0@203494,46X76@74201,COG0629@1,COG0629@2 NA|NA|NA L Domain of unknown function (DUF3127) JOKFNDED_00513 96561.Dole_1993 5.1e-51 207.2 Desulfobacterales Bacteria 1RHUU@1224,2MNF6@213118,2WPAN@28221,42SAT@68525,COG2314@1,COG2314@2 NA|NA|NA S PFAM TM2 domain JOKFNDED_00514 497964.CfE428DRAFT_4607 4.4e-10 72.4 Verrucomicrobia ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 46TXY@74201,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Type II and III secretion system protein JOKFNDED_00516 344747.PM8797T_24941 3.4e-116 424.9 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00517 1123242.JH636434_gene3814 4.8e-124 451.4 Planctomycetes 3.1.6.8 ko:K01134 ko00600,ko04142,map00600,map04142 R04856 RC00231 ko00000,ko00001,ko01000 Bacteria 2IY75@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00518 240016.ABIZ01000001_gene580 2.9e-232 811.2 Verrucomicrobiae Bacteria 2IV6X@203494,46UXB@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_00519 1185876.BN8_01398 3.5e-56 226.1 Cytophagia Bacteria 47N32@768503,4NK5S@976,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) JOKFNDED_00521 497964.CfE428DRAFT_0149 8.4e-126 457.2 Verrucomicrobia Bacteria 46SNN@74201,COG0644@1,COG0644@2 NA|NA|NA C FAD dependent oxidoreductase JOKFNDED_00522 1210884.HG799463_gene9923 1.3e-82 312.8 Planctomycetes Bacteria 2J1IQ@203682,COG1878@1,COG1878@2 NA|NA|NA S Putative cyclase JOKFNDED_00523 1173028.ANKO01000244_gene3949 1.7e-66 259.2 Oscillatoriales Bacteria 1G2GP@1117,1HHDU@1150,COG0384@1,COG0384@2 NA|NA|NA S Phenazine biosynthesis protein JOKFNDED_00525 67275.JOAP01000010_gene626 1.5e-16 92.8 Actinobacteria ko:K02405,ko:K03088 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 2GJ21@201174,COG1595@1,COG1595@2,COG2340@1,COG2340@2 NA|NA|NA K belongs to the sigma-70 factor family JOKFNDED_00527 231434.JQJH01000001_gene1724 1.1e-45 191.8 Beijerinckiaceae 2.4.1.80 ko:K00720 ko00600,ko01100,map00600,map01100 M00066 R01497 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000 4.D.1.4 GT21 Bacteria 1R8UT@1224,2TVQT@28211,3NAHA@45404,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 21 JOKFNDED_00528 322710.Avin_29510 6.5e-69 267.3 Gammaproteobacteria ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MU45@1224,1S4GN@1236,COG1136@1,COG1136@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, ATPase component JOKFNDED_00529 497964.CfE428DRAFT_5134 9.3e-42 177.9 Verrucomicrobia prpC 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 46S8Z@74201,COG0631@1,COG0631@2 NA|NA|NA T SMART protein phosphatase 2C domain protein JOKFNDED_00530 1396141.BATP01000030_gene3690 8e-51 206.8 Verrucomicrobiae ko:K06950 ko00000 Bacteria 2IVQC@203494,46XEW@74201,COG1418@1,COG1418@2 NA|NA|NA S mRNA catabolic process JOKFNDED_00531 497964.CfE428DRAFT_2287 1.2e-103 383.6 Verrucomicrobia argA GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0004358,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00619,ko:K00930,ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226 Bacteria 46SH2@74201,COG0548@1,COG0548@2,COG1246@1,COG1246@2 NA|NA|NA E Acetyltransferase (GNAT) domain JOKFNDED_00532 83406.HDN1F_33390 2.2e-22 113.2 Gammaproteobacteria Bacteria 1R749@1224,1RYRK@1236,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain JOKFNDED_00533 1173025.GEI7407_2231 6.4e-107 394.8 Oscillatoriales 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1GC97@1117,1HEF5@1150,COG2114@1,COG2114@2,COG5000@1,COG5000@2 NA|NA|NA T COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) JOKFNDED_00534 1396141.BATP01000028_gene2302 0.0 1245.3 Verrucomicrobiae Bacteria 2ITPA@203494,46UFX@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Trehalose utilisation JOKFNDED_00535 1396141.BATP01000060_gene4688 2.8e-98 365.2 Verrucomicrobiae ywfI ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 R11522 RC00884 ko00000,ko00001,ko01000 Bacteria 2IVHP@203494,46SQD@74201,COG3253@1,COG3253@2 NA|NA|NA S Chlorite dismutase JOKFNDED_00536 497964.CfE428DRAFT_2424 1e-29 135.6 Verrucomicrobia rnfB ko:K03616,ko:K05337 ko00000 Bacteria 46T2D@74201,COG1141@1,COG1141@2 NA|NA|NA C 4Fe-4S single cluster domain JOKFNDED_00537 497964.CfE428DRAFT_2403 3.1e-17 94.7 Verrucomicrobia Bacteria 46WKB@74201,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) JOKFNDED_00538 1123070.KB899251_gene783 6.7e-17 93.6 Verrucomicrobiae folB 1.13.11.81,3.1.3.18,4.1.2.25,5.1.99.8 ko:K01091,ko:K01633 ko00630,ko00790,ko01100,ko01110,ko01130,map00630,map00790,map01100,map01110,map01130 M00126,M00840 R01334,R03504,R11037,R11073 RC00017,RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUZ3@203494,46YHW@74201,COG1539@1,COG1539@2 NA|NA|NA H Dihydroneopterin aldolase JOKFNDED_00539 243090.RB11397 4.9e-36 157.9 Planctomycetes ko:K13652 ko00000,ko03000 Bacteria 2J2ST@203682,COG3449@1,COG3449@2 NA|NA|NA L SOUL heme-binding protein JOKFNDED_00540 481448.Minf_1084 5.5e-14 83.2 unclassified Verrucomicrobia Bacteria 37H04@326457,46T5Z@74201,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family JOKFNDED_00541 1286631.X805_37170 1.8e-187 662.5 unclassified Burkholderiales arsA 3.6.3.16 ko:K01551 ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 Bacteria 1KK7H@119065,1MUTX@1224,2VK65@28216,COG0003@1,COG0003@2 NA|NA|NA P Anion-transporting ATPase JOKFNDED_00542 1166016.W5S_3470 8.7e-24 116.3 Pectobacterium arsD Bacteria 1MTU7@122277,1RI3A@1224,1S7NG@1236,2DMHQ@1,32RMG@2 NA|NA|NA S Arsenical resistance operon trans-acting repressor ArsD JOKFNDED_00543 641491.DND132_2311 7.4e-25 119.8 Desulfovibrionales arsR 3.6.4.12 ko:K03655,ko:K03892 ko03440,map03440 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1N19R@1224,2MC8X@213115,2WQHU@28221,42TRS@68525,COG0640@1,COG0640@2 NA|NA|NA K SMART regulatory protein ArsR JOKFNDED_00544 1356852.N008_01195 5.1e-13 83.2 Bacteroidetes Bacteria 4PMEU@976,COG2911@1,COG2911@2,COG3391@1,COG3391@2,COG5492@1,COG5492@2 NA|NA|NA Q Concanavalin A-like lectin/glucanases superfamily JOKFNDED_00546 1123070.KB899256_gene2213 2.2e-130 473.0 Verrucomicrobia htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 46T42@74201,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 JOKFNDED_00547 1123070.KB899256_gene2214 2.1e-60 238.8 Verrucomicrobia lemA ko:K03744 ko00000 Bacteria 46V9M@74201,COG1704@1,COG1704@2 NA|NA|NA S PFAM LemA family protein JOKFNDED_00548 497964.CfE428DRAFT_5288 5e-12 79.0 Verrucomicrobia tolQ ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 46V4I@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_00550 240016.ABIZ01000001_gene5195 8.5e-69 267.3 Verrucomicrobiae aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 1.5.5.1,2.7.1.71,4.2.3.4 ko:K00311,ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUD4@203494,46SWG@74201,COG0451@1,COG0451@2,COG0703@1,COG0703@2 NA|NA|NA GM Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate JOKFNDED_00551 1396418.BATQ01000101_gene5441 3e-78 298.9 Verrucomicrobiae phoA 3.1.3.2 ko:K14379 ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323 R00548 RC00017 ko00000,ko00001,ko01000 Bacteria 2IVEZ@203494,46UYA@74201,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase JOKFNDED_00552 756272.Plabr_3004 5.5e-260 903.7 Bacteria Bacteria COG3458@1,COG3458@2 NA|NA|NA Q cephalosporin-C deacetylase activity JOKFNDED_00554 452637.Oter_0912 1.7e-156 559.7 Opitutae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 3K7FZ@414999,46YXP@74201,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter JOKFNDED_00557 247490.KSU1_C1680 9.7e-36 156.8 Planctomycetes fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 2IZNA@203682,COG0764@1,COG0764@2 NA|NA|NA I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) JOKFNDED_00558 391612.CY0110_06249 6.1e-09 69.3 Cyanothece ko:K07052 ko00000 Bacteria 1G0ZJ@1117,3KGVA@43988,COG1266@1,COG1266@2 NA|NA|NA S Abortive infection protein JOKFNDED_00559 314230.DSM3645_27453 3.2e-101 375.6 Planctomycetes Bacteria 2IXDR@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins JOKFNDED_00560 1123070.KB899254_gene1236 3e-59 235.7 Verrucomicrobiae Bacteria 28N07@1,2IW5A@203494,2ZB6S@2,46XKR@74201 NA|NA|NA JOKFNDED_00561 1403819.BATR01000114_gene3908 3.2e-172 611.7 Verrucomicrobia ko:K03290,ko:K08369 ko00000,ko02000 2.A.1,2.A.1.12 Bacteria 46TEM@74201,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter JOKFNDED_00565 497964.CfE428DRAFT_5137 1.1e-55 224.2 Verrucomicrobia lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 46SKZ@74201,COG4591@1,COG4591@2 NA|NA|NA M MacB-like periplasmic core domain JOKFNDED_00566 1396418.BATQ01000175_gene2772 1.7e-16 93.6 Verrucomicrobiae Bacteria 2IV0N@203494,46ZIK@74201,COG1714@1,COG1714@2 NA|NA|NA S RDD family JOKFNDED_00567 497964.CfE428DRAFT_2513 3.1e-114 419.1 Bacteria 2.4.1.18 ko:K03406,ko:K16149 ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko02035 GH57 Bacteria COG1543@1,COG1543@2 NA|NA|NA G Belongs to the glycosyl hydrolase 57 family JOKFNDED_00568 1396418.BATQ01000175_gene2771 6.6e-56 223.8 Verrucomicrobiae polB 2.7.7.7 ko:K02336,ko:K06877,ko:K07501 ko00000,ko01000,ko03400 Bacteria 2IUC2@203494,46SS2@74201,COG0417@1,COG0417@2 NA|NA|NA L RNase_H superfamily JOKFNDED_00569 1304284.L21TH_2026 6.9e-76 291.2 Clostridia sbcD ko:K03547 ko00000,ko03400 Bacteria 1V3MP@1239,24J4M@186801,COG0420@1,COG0420@2 NA|NA|NA L Calcineurin-like phosphoesterase superfamily domain JOKFNDED_00570 1031288.AXAA01000010_gene469 8.2e-50 205.7 Clostridia CP_0646 ko:K03546 ko00000,ko03400 Bacteria 1UQNY@1239,24UHC@186801,COG0419@1,COG0419@2,COG1196@1,COG1196@2 NA|NA|NA L AAA domain JOKFNDED_00571 314230.DSM3645_13480 4.5e-136 491.5 Planctomycetes Bacteria 2J1QG@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00573 933262.AXAM01000043_gene1186 9.3e-24 116.3 Proteobacteria Bacteria 1QUPK@1224,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins JOKFNDED_00574 794903.OPIT5_04415 1.2e-175 622.9 Opitutae 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 3K8Y8@414999,46XT4@74201,COG3550@1,COG3550@2 NA|NA|NA S Pfam:HipA_N JOKFNDED_00575 497964.CfE428DRAFT_1556 2.5e-170 605.1 Verrucomicrobia hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 46S67@74201,COG0001@1,COG0001@2 NA|NA|NA H intramolecular transferase activity, transferring amino groups JOKFNDED_00578 1396141.BATP01000007_gene5693 2.9e-77 295.8 Verrucomicrobiae galK 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IU6C@203494,46V7W@74201,COG0153@1,COG0153@2 NA|NA|NA G Galactokinase galactose-binding signature JOKFNDED_00580 1403819.BATR01000168_gene5801 1.3e-139 503.1 Verrucomicrobiae Bacteria 2IUBR@203494,46VEA@74201,COG0845@1,COG0845@2 NA|NA|NA M HlyD family secretion protein JOKFNDED_00582 240016.ABIZ01000001_gene1452 3.1e-119 435.3 Verrucomicrobiae gbd 1.1.1.1,1.1.1.61 ko:K00001,ko:K00043,ko:K00100,ko:K13954 ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220 R00623,R00754,R01644,R02124,R03544,R03545,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2IUNH@203494,46TD9@74201,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase JOKFNDED_00583 1396141.BATP01000060_gene4583 1.5e-171 609.4 Verrucomicrobiae gcs2 Bacteria 2IU2U@203494,46TR2@74201,COG2308@1,COG2308@2 NA|NA|NA S Circularly permuted ATP-grasp type 2 JOKFNDED_00584 1396141.BATP01000060_gene4584 3.9e-59 235.3 Verrucomicrobiae Bacteria 2IU62@203494,46S7Q@74201,COG2307@1,COG2307@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. JOKFNDED_00587 1403819.BATR01000112_gene3799 1.8e-131 476.1 Bacteria opdC Bacteria COG3203@1,COG3203@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane JOKFNDED_00588 1125863.JAFN01000001_gene1256 1.3e-84 320.5 Deltaproteobacteria insA Bacteria 1MWAV@1224,2X6S2@28221,43BD6@68525,COG5659@1,COG5659@2 NA|NA|NA L DDE superfamily endonuclease JOKFNDED_00591 1403819.BATR01000191_gene6566 4.9e-100 370.5 Verrucomicrobiae tuf GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 iSB619.SA_RS02960 Bacteria 2ITQE@203494,46SFG@74201,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis JOKFNDED_00593 1396141.BATP01000023_gene540 2.7e-13 80.9 Verrucomicrobiae secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2IUWV@203494,46T9W@74201,COG0690@1,COG0690@2 NA|NA|NA U SecE/Sec61-gamma subunits of protein translocation complex JOKFNDED_00594 1123070.KB899254_gene1249 8.3e-62 243.4 Verrucomicrobiae nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2IU6S@203494,46SR6@74201,COG0250@1,COG0250@2 NA|NA|NA K In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. JOKFNDED_00595 1396141.BATP01000023_gene538 2.6e-52 211.5 Verrucomicrobiae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUAM@203494,46SPZ@74201,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors JOKFNDED_00596 497964.CfE428DRAFT_5605 3.8e-85 321.2 Verrucomicrobia rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 46S7K@74201,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release JOKFNDED_00597 1403819.BATR01000191_gene6561 2.2e-45 188.7 Verrucomicrobiae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUF1@203494,46T4Q@74201,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors JOKFNDED_00598 158500.BV97_04219 1.2e-32 146.0 Sphingomonadales rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RGU4@1224,2K4H8@204457,2U9FX@28211,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation JOKFNDED_00604 342113.DM82_1010 1.4e-81 309.7 Burkholderiaceae vdlC Bacteria 1KIMH@119060,1RGKZ@1224,2WGI9@28216,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family JOKFNDED_00605 1403819.BATR01000183_gene6340 5.8e-29 134.4 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_00607 344747.PM8797T_19914 4.3e-67 261.5 Planctomycetes yoaT Bacteria 2J240@203682,COG3739@1,COG3739@2 NA|NA|NA S Protein of unknown function (DUF817) JOKFNDED_00608 497964.CfE428DRAFT_4576 1.5e-12 79.0 Verrucomicrobia Bacteria 2EMF0@1,33F3U@2,46TA3@74201 NA|NA|NA S Stress responsive A/B Barrel Domain JOKFNDED_00609 1396141.BATP01000045_gene1775 1.4e-36 159.1 Verrucomicrobiae nuoA 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IUK0@203494,46T33@74201,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient JOKFNDED_00610 1396141.BATP01000045_gene1776 2.3e-27 127.9 Verrucomicrobiae Bacteria 2FK8F@1,2IUTA@203494,34BW5@2,46WAI@74201 NA|NA|NA JOKFNDED_00612 1185876.BN8_03977 2.1e-147 530.0 Cytophagia Bacteria 47JIJ@768503,4NEZ5@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Membrane-bound dehydrogenase domain protein JOKFNDED_00613 243090.RB6332 6.9e-56 224.2 Planctomycetes 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 2IZUU@203682,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase JOKFNDED_00614 756272.Plabr_3179 1.2e-64 253.1 Planctomycetes kdgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXBP@203682,COG0800@1,COG0800@2 NA|NA|NA G PFAM KDPG and KHG aldolase JOKFNDED_00615 675815.VOA_001176 9.6e-216 757.3 Vibrionales ko:K08676 ko00000,ko01000,ko01002 Bacteria 1MX41@1224,1RP38@1236,1XU85@135623,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog JOKFNDED_00616 1123269.NX02_10950 2.4e-24 119.4 Alphaproteobacteria 3.4.21.66,3.5.1.28 ko:K01448,ko:K02395,ko:K08651,ko:K17733 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036,ko03110 Bacteria 1NTE0@1224,2UPCG@28211,COG0860@1,COG0860@2,COG1705@1,COG1705@2 NA|NA|NA MNU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase JOKFNDED_00617 344747.PM8797T_14254 1.2e-206 726.1 Planctomycetes Bacteria 2IXNP@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00618 344747.PM8797T_14249 4.8e-87 328.2 Planctomycetes Bacteria 2IYRF@203682,COG3064@1,COG3064@2 NA|NA|NA M Planctomycete cytochrome C JOKFNDED_00619 344747.PM8797T_14194 3.3e-55 222.2 Planctomycetes Bacteria 2J0EG@203682,COG3219@1,COG3219@2 NA|NA|NA S Putative DNA-binding domain JOKFNDED_00621 1089550.ATTH01000002_gene84 2.3e-68 265.8 Bacteroidetes Bacteria 4NES7@976,COG3000@1,COG3000@2 NA|NA|NA I sterol desaturase JOKFNDED_00622 452637.Oter_0307 8.5e-65 253.8 Bacteria Bacteria COG0398@1,COG0398@2 NA|NA|NA M Pfam SNARE associated Golgi protein JOKFNDED_00623 690850.Desaf_0092 1.1e-98 367.1 Desulfovibrionales 3.4.14.13 ko:K09931,ko:K20742 ko00000,ko01000,ko01002 Bacteria 1RA75@1224,2MH8H@213115,2X6YG@28221,42QB9@68525,COG1215@1,COG1215@2,COG3222@1,COG3222@2 NA|NA|NA M Glycosyl transferase JOKFNDED_00625 240016.ABIZ01000001_gene637 4.5e-58 232.6 Verrucomicrobia Bacteria 2EQIM@1,2ZBQ8@2,46TFZ@74201 NA|NA|NA S Domain of unknown function (DUF4129) JOKFNDED_00626 439235.Dalk_0970 4.5e-17 94.0 Deltaproteobacteria Bacteria 1P7Y2@1224,2EE20@1,2WXV7@28221,337WQ@2,433SZ@68525 NA|NA|NA JOKFNDED_00627 1403819.BATR01000055_gene1712 1.5e-08 67.4 Bacteria Bacteria 2EG13@1,339T4@2 NA|NA|NA JOKFNDED_00628 240016.ABIZ01000001_gene2131 2e-74 285.8 Verrucomicrobiae pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 iAF1260.b2564,iAF987.Gmet_1885,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 Bacteria 2ITP1@203494,46SJT@74201,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate JOKFNDED_00629 497964.CfE428DRAFT_2171 3.9e-26 125.2 Verrucomicrobia Bacteria 46VEG@74201,COG1376@1,COG1376@2 NA|NA|NA S PFAM ErfK YbiS YcfS YnhG family protein JOKFNDED_00630 266779.Meso_2421 5.2e-198 697.6 Alphaproteobacteria 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 1MVM7@1224,2VF2F@28211,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position JOKFNDED_00631 1121271.AUCM01000006_gene196 2.8e-72 279.3 Alphaproteobacteria Bacteria 1MW31@1224,2TRR9@28211,COG4307@1,COG4307@2 NA|NA|NA S Protein conserved in bacteria JOKFNDED_00632 243090.RB1458 1.4e-154 552.7 Planctomycetes Bacteria 28HUC@1,2IYZP@203682,2Z7KP@2 NA|NA|NA JOKFNDED_00633 1403819.BATR01000146_gene4973 5.2e-41 173.7 Bacteria Bacteria COG5470@1,COG5470@2 NA|NA|NA JOKFNDED_00634 745310.G432_13395 2.7e-106 391.7 Sphingomonadales Bacteria 1MWZE@1224,2K3R9@204457,2U09J@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Short chain dehydrogenase JOKFNDED_00635 1254432.SCE1572_20225 1.3e-107 396.4 Myxococcales Bacteria 1N0FA@1224,2WYWH@28221,2Z0T1@29,43DUB@68525,COG2207@1,COG2207@2 NA|NA|NA K Cupin JOKFNDED_00636 452637.Oter_1812 9.8e-29 134.0 Verrucomicrobia Bacteria 46T69@74201,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family JOKFNDED_00638 1403819.BATR01000055_gene1730 2.6e-232 811.2 Verrucomicrobiae Bacteria 2IV5Z@203494,46UP0@74201,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_00639 1403819.BATR01000055_gene1729 0.0 1369.0 Verrucomicrobiae Bacteria 2IVEI@203494,46U4A@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_00640 96561.Dole_2171 6.4e-11 75.5 Desulfobacterales ko:K20951,ko:K20952 ko05111,map05111 ko00000,ko00001 Bacteria 1QD4I@1224,2MNSY@213118,2X9BC@28221,435MR@68525,COG1075@1,COG1075@2,COG1572@1,COG1572@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold JOKFNDED_00641 1200792.AKYF01000008_gene778 3.5e-11 75.9 Bacilli ddpX 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1V76X@1239,4HINF@91061,COG2173@1,COG2173@2 NA|NA|NA E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide JOKFNDED_00642 926554.KI912664_gene1577 2.9e-22 113.2 Deinococcus-Thermus Bacteria 1WNBY@1297,29XYR@1,30JRD@2 NA|NA|NA S Lysyl oxidase JOKFNDED_00643 452637.Oter_1728 1.1e-43 184.5 Opitutae Bacteria 3K7YS@414999,46TKR@74201,COG0642@1,COG2205@2 NA|NA|NA T histidine kinase HAMP region domain protein JOKFNDED_00644 349521.HCH_00579 4.9e-48 198.0 Oceanospirillales Bacteria 1MU67@1224,1RNWH@1236,1XJ8U@135619,COG0745@1,COG0745@2 NA|NA|NA K Response regulator receiver JOKFNDED_00645 1000565.METUNv1_01637 2.6e-30 140.6 Betaproteobacteria Bacteria 1RAZA@1224,2EMF3@1,2VQE2@28216,2ZKNW@2 NA|NA|NA S PEP-CTERM motif JOKFNDED_00648 1396418.BATQ01000179_gene3142 2e-281 977.2 Verrucomicrobiae 3.4.21.66 ko:K02396,ko:K08651 ko02040,map02040 ko00000,ko00001,ko01000,ko01002,ko02035,ko03110 Bacteria 2IUFG@203494,46UMW@74201,COG1345@1,COG1345@2,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family JOKFNDED_00651 314230.DSM3645_02263 4.7e-134 484.6 Planctomycetes Bacteria 2IZV2@203682,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily JOKFNDED_00652 497964.CfE428DRAFT_2802 3.5e-144 518.1 Verrucomicrobia 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 46URQ@74201,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M28 JOKFNDED_00653 794903.OPIT5_18725 6.2e-212 743.4 Opitutae 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 3K9DB@414999,46UCU@74201,COG0174@1,COG0174@2 NA|NA|NA E Glutamine synthetase, catalytic domain JOKFNDED_00654 717785.HYPMC_2722 2.3e-110 406.0 Alphaproteobacteria ko:K00479 ko00000 Bacteria 1MWXW@1224,2TVNW@28211,COG4638@1,COG4638@2 NA|NA|NA P Rieske 2Fe-2S JOKFNDED_00656 1142394.PSMK_13240 9.2e-150 537.0 Planctomycetes 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2IZ5S@203682,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase JOKFNDED_00657 1142394.PSMK_13250 2.6e-66 258.8 Bacteria 3.5.2.10 ko:K01470 ko00330,map00330 R01884 RC00615 ko00000,ko00001,ko01000 Bacteria COG1402@1,COG1402@2 NA|NA|NA I creatininase JOKFNDED_00658 583355.Caka_2074 8.4e-16 89.7 Opitutae ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 3K8RN@414999,46THJ@74201,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities JOKFNDED_00660 497964.CfE428DRAFT_6606 5.3e-182 644.0 Bacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1368@1,COG1368@2 NA|NA|NA M sulfuric ester hydrolase activity JOKFNDED_00661 340177.Cag_0545 2.7e-10 71.2 Bacteria Bacteria COG4226@1,COG4226@2 NA|NA|NA K protein encoded in hypervariable junctions of pilus gene clusters JOKFNDED_00662 1123054.KB907705_gene2384 3.6e-25 121.3 Chromatiales Bacteria 1N1T4@1224,1SE91@1236,1WZFG@135613,COG1569@1,COG1569@2 NA|NA|NA S PIN domain JOKFNDED_00663 497964.CfE428DRAFT_4475 3.5e-188 665.6 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_00664 626418.bglu_1g09350 1.7e-47 195.7 Burkholderiaceae Bacteria 1K7CM@119060,1QTZ4@1224,2VSAH@28216,COG0454@1,COG0454@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase JOKFNDED_00665 1123070.KB899263_gene1766 1.2e-59 236.5 Verrucomicrobiae yggS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 ko:K06997 ko00000 Bacteria 2IU7Y@203494,46SV2@74201,COG0325@1,COG0325@2 NA|NA|NA S Alanine racemase, N-terminal domain JOKFNDED_00666 1123024.AUII01000001_gene3028 8.3e-26 123.2 Actinobacteria Bacteria 2GSS6@201174,COG3744@1,COG3744@2 NA|NA|NA S PilT protein domain protein JOKFNDED_00667 977880.pRALTA_0623 3.1e-12 77.8 Burkholderiaceae 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1K9M1@119060,1N7BG@1224,2VY0B@28216,COG4118@1,COG4118@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module JOKFNDED_00668 240016.ABIZ01000001_gene5094 3.8e-92 345.1 Verrucomicrobiae purN 2.1.2.2,2.7.1.167,2.7.7.39,2.7.7.70 ko:K00980,ko:K03272,ko:K11175 ko00230,ko00540,ko00564,ko00670,ko01100,ko01110,ko01130,map00230,map00540,map00564,map00670,map01100,map01110,map01130 M00048,M00064 R00856,R04325,R04326,R05644,R05646 RC00002,RC00026,RC00078,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000,ko01005 iJN678.purN Bacteria 2IWN8@203494,46SUW@74201,COG0299@1,COG0299@2,COG0615@1,COG0615@2 NA|NA|NA FIM Cytidylyltransferase-like JOKFNDED_00669 1403819.BATR01000176_gene5947 6e-149 533.9 Verrucomicrobiae ampS5 ko:K19689 ko00000,ko01000,ko01002 Bacteria 2ITU9@203494,46SAI@74201,COG2309@1,COG2309@2 NA|NA|NA E Thermophilic metalloprotease (M29) JOKFNDED_00672 1173028.ANKO01000243_gene4219 8.8e-39 167.2 Oscillatoriales cbbZp 1.17.99.6,3.1.3.18 ko:K01091,ko:K18979 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000,ko03016 Bacteria 1G52P@1117,1HB0I@1150,COG0546@1,COG0546@2 NA|NA|NA S PFAM Haloacid dehalogenase-like hydrolase JOKFNDED_00673 1123070.KB899255_gene1358 3.3e-88 331.6 Verrucomicrobiae ddpF ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 iEC042_1314.EC042_1615,iECH74115_1262.ECH74115_2095,iECSP_1301.ECSP_1968,iECUMN_1333.ECUMN_1737,iECW_1372.ECW_m1611,iECs_1301.ECs2087,iEKO11_1354.EKO11_2337,iWFL_1372.ECW_m1611,iZ_1308.Z2227 Bacteria 2ITZ2@203494,46SHJ@74201,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities JOKFNDED_00674 1163617.SCD_n02820 3.5e-21 107.8 Betaproteobacteria ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1N6WV@1224,2VWSV@28216,COG0664@1,COG0664@2 NA|NA|NA T PFAM Cyclic nucleotide-binding JOKFNDED_00675 469383.Cwoe_3361 1.8e-25 122.9 Actinobacteria ko:K02927 ko03010,map03010 M00177,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GSXC@201174,COG5272@1,COG5272@2 NA|NA|NA O Ubiquitin homologues JOKFNDED_00678 1123508.JH636440_gene2398 6.8e-210 737.3 Planctomycetes Bacteria 2J52X@203682,COG0492@1,COG0492@2 NA|NA|NA O secreted protein-putative xanthan lyase related JOKFNDED_00679 530564.Psta_3957 2.6e-15 88.2 Planctomycetes Bacteria 2IYJZ@203682,COG1793@1,COG1793@2 NA|NA|NA L Domain of Unknown Function (DUF1080) JOKFNDED_00682 1396141.BATP01000030_gene3614 5.9e-141 507.3 Verrucomicrobiae rlmN 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2ITGQ@203494,46SBD@74201,COG0820@1,COG0820@2 NA|NA|NA J Elongator protein 3, MiaB family, Radical SAM JOKFNDED_00683 1396141.BATP01000023_gene745 2.4e-93 349.0 Verrucomicrobiae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU31@203494,46SVM@74201,COG1482@1,COG1482@2 NA|NA|NA G Phosphomannose isomerase type I JOKFNDED_00684 1396141.BATP01000007_gene5786 6.2e-50 203.8 Verrucomicrobiae fur GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K03711 ko00000,ko03000 Bacteria 2IUEJ@203494,46V9Y@74201,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family JOKFNDED_00685 1403819.BATR01000181_gene6167 7.7e-178 630.2 Verrucomicrobiae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K01755,ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844,M00845 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argH Bacteria 2ITKH@203494,46SCX@74201,COG0165@1,COG0165@2 NA|NA|NA E Argininosuccinate lyase C-terminal JOKFNDED_00686 497964.CfE428DRAFT_0850 3.4e-80 305.4 Verrucomicrobia recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 46UKV@74201,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP JOKFNDED_00688 497964.CfE428DRAFT_3702 3.7e-159 568.2 Verrucomicrobia ko:K01138 ko00000,ko01000 Bacteria 46TNU@74201,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase JOKFNDED_00689 1396418.BATQ01000008_gene1478 3.7e-81 308.9 Verrucomicrobiae Bacteria 28J2H@1,2IU6E@203494,2Z8YZ@2,46ZAA@74201 NA|NA|NA JOKFNDED_00690 497964.CfE428DRAFT_4099 4.7e-69 268.5 Verrucomicrobia Bacteria 28JRZ@1,2Z9HI@2,46TRU@74201 NA|NA|NA S Domain of unknown function (DUF4126) JOKFNDED_00691 1396418.BATQ01000058_gene110 2.6e-09 68.2 Verrucomicrobia Bacteria 2EMGZ@1,33F5K@2,46TB4@74201 NA|NA|NA JOKFNDED_00692 1396141.BATP01000039_gene1430 2.7e-38 166.4 Bacteria Bacteria 2BKPT@1,32F5G@2 NA|NA|NA S PcfJ-like protein JOKFNDED_00693 1396141.BATP01000041_gene2218 2e-172 612.1 Verrucomicrobiae lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 ko:K01586,ko:K05366 ko00300,ko00550,ko01100,ko01110,ko01120,ko01130,ko01230,ko01501,map00300,map00550,map01100,map01110,map01120,map01130,map01230,map01501 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000,ko01003,ko01011 GT51 iLJ478.TM1517 Bacteria 2ITWM@203494,46SC5@74201,COG0019@1,COG0019@2 NA|NA|NA E Pyridoxal-dependent decarboxylase, pyridoxal binding domain JOKFNDED_00694 1047013.AQSP01000088_gene1638 6.2e-13 79.7 Bacteria Bacteria 2E9PU@1,333W6@2 NA|NA|NA JOKFNDED_00695 396595.TK90_2100 1.9e-21 108.2 Chromatiales ko:K06218 ko00000,ko02048 Bacteria 1N80B@1224,1SDK6@1236,1WZ7U@135613,COG2026@1,COG2026@2 NA|NA|NA DJ PFAM plasmid JOKFNDED_00696 667632.KB890169_gene5037 1.7e-33 149.1 Burkholderiaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1K7JP@119060,1RD5K@1224,2VQ3A@28216,COG0822@1,COG0822@2 NA|NA|NA C NifU-like N terminal domain JOKFNDED_00699 497964.CfE428DRAFT_5496 1.1e-181 644.0 Verrucomicrobia 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 46TSJ@74201,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain JOKFNDED_00700 1458427.BAWN01000013_gene920 5.4e-112 411.4 Betaproteobacteria ko:K07133 ko00000 Bacteria 1R3UA@1224,2VQ1T@28216,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) JOKFNDED_00701 1396141.BATP01000007_gene5676 0.0 1171.8 Verrucomicrobiae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 2IU1F@203494,46SGP@74201,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner JOKFNDED_00702 1396418.BATQ01000019_gene4989 6.8e-75 287.7 Verrucomicrobiae amiD2 3.5.1.28 ko:K01448,ko:K02172 ko01501,ko01503,map01501,map01503 M00627,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036 Bacteria 2IU3W@203494,46SS7@74201,COG0860@1,COG0860@2 NA|NA|NA M Ami_3 JOKFNDED_00704 1121403.AUCV01000013_gene3916 1.7e-77 296.2 Proteobacteria 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1R7HB@1224,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family JOKFNDED_00706 397945.Aave_1322 2.5e-173 614.8 Comamonadaceae eno GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1MU1N@1224,2VH7Y@28216,4A9T6@80864,COG0148@1,COG0148@2 NA|NA|NA F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis JOKFNDED_00708 1318628.MARLIPOL_08334 2.6e-26 125.9 Gammaproteobacteria Bacteria 1QZXK@1224,1SHD6@1236,COG2242@1,COG2242@2 NA|NA|NA H Fkbm family JOKFNDED_00709 1396141.BATP01000005_gene5951 2.4e-131 475.3 Verrucomicrobiae pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,4.2.1.51,4.2.1.91,5.4.99.5 ko:K01713,ko:K04518,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITT8@203494,46U8V@74201,COG0077@1,COG0077@2 NA|NA|NA E Chorismate mutase type II JOKFNDED_00710 1403819.BATR01000094_gene3002 1.4e-46 193.4 Verrucomicrobiae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 2IUTS@203494,46VRU@74201,COG1386@1,COG1386@2 NA|NA|NA K Segregation and condensation complex subunit ScpB JOKFNDED_00711 744872.Spica_2681 1e-74 287.0 Spirochaetes Bacteria 2J5IH@203691,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system JOKFNDED_00712 243231.GSU1367 1.4e-31 143.3 Deltaproteobacteria Bacteria 1RGNP@1224,2WQPR@28221,42UD1@68525,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score JOKFNDED_00713 1403819.BATR01000094_gene3009 3e-74 285.4 Verrucomicrobiae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 2IUKJ@203494,46UBD@74201,COG1354@1,COG1354@2 NA|NA|NA D Segregation and condensation protein ScpA JOKFNDED_00714 375286.mma_0621 7.6e-40 170.6 Oxalobacteraceae Bacteria 1RHQN@1224,2VR8T@28216,473F8@75682,COG2860@1,COG2860@2 NA|NA|NA S UPF0126 domain JOKFNDED_00715 1396141.BATP01000016_gene2844 3.2e-111 409.5 Verrucomicrobiae ccsA Bacteria 2IU24@203494,46VBM@74201,COG0755@1,COG0755@2 NA|NA|NA O Cytochrome C assembly protein JOKFNDED_00716 240016.ABIZ01000001_gene3954 1.3e-62 247.3 Verrucomicrobiae Bacteria 2IUGM@203494,46SUY@74201,COG1333@1,COG1333@2 NA|NA|NA O ResB-like family JOKFNDED_00717 1396418.BATQ01000064_gene1597 3.5e-32 145.2 Verrucomicrobiae Bacteria 2E533@1,2IUXW@203494,32ZW9@2,46X7Y@74201 NA|NA|NA JOKFNDED_00718 1123278.KB893422_gene1566 1.4e-44 188.0 Cytophagia Bacteria 47MG0@768503,4NFES@976,COG4886@1,COG4886@2 NA|NA|NA S Planctomycete cytochrome C JOKFNDED_00721 1403819.BATR01000088_gene2585 9e-73 280.4 Verrucomicrobiae Bacteria 28NXH@1,2IUAE@203494,2ZBV3@2,46TF0@74201 NA|NA|NA JOKFNDED_00724 382464.ABSI01000005_gene1204 4.6e-69 267.7 Verrucomicrobiae leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2IU7P@203494,46TAY@74201,COG0066@1,COG0066@2 NA|NA|NA E Aconitase C-terminal domain JOKFNDED_00725 756272.Plabr_0478 5.5e-113 414.1 Planctomycetes 3.6.3.38 ko:K07214,ko:K09689 ko02010,map02010 M00249 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101 Bacteria 2IWXM@203682,COG2382@1,COG2382@2 NA|NA|NA P esterase JOKFNDED_00726 1396418.BATQ01000147_gene3553 6.6e-69 267.7 Verrucomicrobia 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 46TMI@74201,COG3386@1,COG3386@2 NA|NA|NA G SMP-30 Gluconolaconase LRE domain protein JOKFNDED_00728 1380350.JIAP01000023_gene3698 1.6e-66 258.8 Phyllobacteriaceae Bacteria 1MZY9@1224,2UB9G@28211,43MIF@69277,COG4675@1,COG4675@2 NA|NA|NA S Tail Collar domain JOKFNDED_00729 118173.KB235914_gene766 7.3e-81 306.6 Oscillatoriales Bacteria 1G7A6@1117,1HDSQ@1150,COG4675@1,COG4675@2 NA|NA|NA S Phage Tail Collar Domain JOKFNDED_00730 118173.KB235914_gene769 6e-116 427.6 Oscillatoriales 3.1.4.50 ko:K01127,ko:K20276 ko00563,ko02024,map00563,map02024 R06623 ko00000,ko00001,ko01000 Bacteria 1G0ZC@1117,1H8KD@1150,COG1572@1,COG1572@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2,COG3210@1,COG3210@2 NA|NA|NA Q PFAM Hemolysin-type calcium-binding repeat (2 copies) JOKFNDED_00731 497964.CfE428DRAFT_4864 7e-54 217.6 Verrucomicrobia ko:K03088 ko00000,ko03021 Bacteria 46VE8@74201,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_00734 278957.ABEA03000118_gene1137 2.1e-130 472.6 Opitutae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 3K7ME@414999,46S7M@74201,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) JOKFNDED_00735 595460.RRSWK_01095 6.1e-93 347.4 Planctomycetes Bacteria 2IY3G@203682,COG3828@1,COG3828@2 NA|NA|NA C PFAM coagulation factor 5 8 type JOKFNDED_00736 344747.PM8797T_20488 1.5e-85 322.8 Planctomycetes Bacteria 2IZ9W@203682,COG3568@1,COG3568@2 NA|NA|NA S PFAM Endonuclease Exonuclease phosphatase JOKFNDED_00737 1123242.JH636435_gene1598 2.9e-21 108.2 Planctomycetes ko:K01463 ko00000,ko01000 Bacteria 2IY80@203682,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase JOKFNDED_00738 1046724.KB889930_gene1321 1.1e-126 460.3 Gammaproteobacteria ko:K19304 ko00000,ko01000,ko01002,ko01011 Bacteria 1MXRZ@1224,1RR9E@1236,COG4942@1,COG4942@2 NA|NA|NA D Protein of unknown function (DUF3375) JOKFNDED_00740 240016.ABIZ01000001_gene164 0.0 1160.6 Verrucomicrobia Bacteria 46TUV@74201,COG1020@1,COG1020@2 NA|NA|NA Q Protein of unknown function (DUF1587) JOKFNDED_00741 344747.PM8797T_14012 1.1e-176 626.3 Planctomycetes Bacteria 2J1SZ@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_00742 1396418.BATQ01000078_gene606 1.1e-65 256.5 Verrucomicrobia ko:K00612 ko00000,ko01000 Bacteria 46WAY@74201,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_00743 1396141.BATP01000004_gene5836 3.6e-20 104.8 Verrucomicrobiae Bacteria 2EES1@1,2IUVA@203494,338JQ@2,46X7G@74201 NA|NA|NA S Protein of unknown function (DUF3592) JOKFNDED_00744 1396418.BATQ01000153_gene2269 1e-41 176.4 Verrucomicrobiae yqeY ko:K09117 ko00000 Bacteria 2IUKM@203494,46T4B@74201,COG1610@1,COG1610@2 NA|NA|NA S Yqey-like protein JOKFNDED_00745 497964.CfE428DRAFT_4693 4e-44 184.9 Verrucomicrobia ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60,4.6.1.12 ko:K00991,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 46T2A@74201,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) JOKFNDED_00746 497964.CfE428DRAFT_2891 4.6e-55 220.7 Verrucomicrobia queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 46VC9@74201,COG0720@1,COG0720@2 NA|NA|NA H 6-pyruvoyl tetrahydropterin synthase JOKFNDED_00747 1403819.BATR01000185_gene6422 6.5e-17 94.4 Verrucomicrobiae Bacteria 2EGCD@1,2IWC7@203494,33A46@2,46Z2P@74201 NA|NA|NA S Domain of unknown function (DUF4190) JOKFNDED_00748 383372.Rcas_2074 5.8e-74 285.0 Chloroflexia 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 2GBEJ@200795,376K7@32061,COG1231@1,COG1231@2 NA|NA|NA E PFAM amine oxidase JOKFNDED_00749 1266909.AUAG01000018_gene284 2e-29 135.6 Gammaproteobacteria Bacteria 1N1KS@1224,1S4QZ@1236,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_00751 240016.ABIZ01000001_gene3864 0.0 1155.6 Verrucomicrobiae gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2IU0E@203494,46SDH@74201,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner JOKFNDED_00752 1142394.PSMK_27540 2.4e-53 215.3 Bacteria Bacteria COG4636@1,COG4636@2 NA|NA|NA D protein conserved in cyanobacteria JOKFNDED_00753 1403819.BATR01000118_gene4213 3.2e-289 1001.1 Verrucomicrobiae Bacteria 2ITPA@203494,46UFX@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Trehalose utilisation JOKFNDED_00754 1396141.BATP01000007_gene5611 9.4e-38 163.7 Verrucomicrobiae gph1 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 2IVT2@203494,46SW1@74201,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase JOKFNDED_00755 1396141.BATP01000007_gene5612 1.7e-45 189.5 Verrucomicrobiae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2IUB3@203494,46SU6@74201,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins JOKFNDED_00756 1396141.BATP01000007_gene5613 5.3e-14 83.2 Verrucomicrobiae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2ITM8@203494,46S5A@74201,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) JOKFNDED_00757 1157708.KB907453_gene4405 5.4e-70 271.2 Comamonadaceae yciC Bacteria 1MVZV@1224,2VIK7@28216,4ACUG@80864,COG0523@1,COG0523@2 NA|NA|NA S Cobalamin synthesis protein cobW C-terminal domain JOKFNDED_00759 1242864.D187_006563 1.3e-57 229.9 Deltaproteobacteria 2.3.2.5 ko:K00683 ko00000,ko01000 Bacteria 1R9YU@1224,2WNVI@28221,42RYU@68525,COG3823@1,COG3823@2 NA|NA|NA O PFAM Glutamine cyclotransferase JOKFNDED_00760 509190.Cseg_3197 2.8e-30 138.3 Caulobacterales sufE ko:K02426 ko00000 Bacteria 1RI8F@1224,2KGUP@204458,2U9A2@28211,COG2166@1,COG2166@2 NA|NA|NA S Fe-S metabolism associated JOKFNDED_00761 1123023.JIAI01000017_gene3528 6.5e-09 67.4 Pseudonocardiales ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 2IP0J@201174,4ECNB@85010,COG1487@1,COG1487@2 NA|NA|NA S PIN domain JOKFNDED_00763 240016.ABIZ01000001_gene4368 5e-128 464.5 Verrucomicrobia Bacteria 46TPB@74201,COG2072@1,COG2072@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase JOKFNDED_00764 1396418.BATQ01000049_gene481 7.1e-32 144.1 Verrucomicrobiae Bacteria 2D74M@1,2IW2S@203494,32TNB@2,46WZS@74201 NA|NA|NA JOKFNDED_00765 1173264.KI913949_gene3739 1.5e-114 420.2 Oscillatoriales iSB619.SA_RS13570 Bacteria 1G1IJ@1117,1HAA8@1150,COG0370@1,COG0370@2 NA|NA|NA P Nucleoside recognition JOKFNDED_00766 1123261.AXDW01000001_gene1442 1.1e-46 193.0 Xanthomonadales hisI 3.5.4.19 ko:K01496 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04037 RC01055 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW67@1224,1RMV4@1236,1X4HM@135614,COG0139@1,COG0139@2 NA|NA|NA E Histidine biosynthesis bifunctional protein HisIE JOKFNDED_00767 314292.VAS14_04128 1.7e-10 71.6 Vibrionales Bacteria 1NGYD@1224,1SGRD@1236,1Y1VE@135623,2EGWS@1,33ANX@2 NA|NA|NA JOKFNDED_00769 1123070.KB899247_gene1482 3e-48 199.1 Verrucomicrobiae yeiR GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 Bacteria 2IW5N@203494,46XKW@74201,COG0523@1,COG0523@2 NA|NA|NA S Cobalamin synthesis protein cobW C-terminal domain JOKFNDED_00770 1396141.BATP01000027_gene1129 7.8e-37 161.4 Bacteria Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity JOKFNDED_00771 756272.Plabr_4222 1.2e-108 400.2 Planctomycetes Bacteria 2IYIY@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_00772 1396141.BATP01000060_gene4765 6.4e-133 483.4 Verrucomicrobiae oprH 2.2.1.6,3.2.1.4,4.1.3.1 ko:K01179,ko:K01637,ko:K01652,ko:K02014,ko:K16087,ko:K20276 ko00290,ko00500,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko02024,map00290,map00500,map00630,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map02024 M00012,M00019,M00570 R00006,R00014,R00226,R00479,R03050,R04672,R04673,R06200,R08648,R11307,R11308 RC00027,RC00106,RC00311,RC00313,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.14,1.B.14.2 GH5,GH9 Bacteria 2IVEQ@203494,46Z9Q@74201,COG0028@1,COG0028@2,COG2730@1,COG2730@2,COG2755@1,COG2755@2,COG2931@1,COG2931@2,COG3506@1,COG3506@2,COG3637@1,COG3637@2,COG4733@1,COG4733@2,COG5184@1,COG5184@2 NA|NA|NA DEGMUZ Repeats in polycystic kidney disease 1 (PKD1) and other proteins JOKFNDED_00773 871968.DESME_00860 3.1e-08 63.2 Peptococcaceae moaC GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 1V3J4@1239,24H9F@186801,261ZC@186807,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) JOKFNDED_00774 926559.JoomaDRAFT_3458 1.6e-112 412.5 Flavobacteriia Bacteria 1HYU7@117743,4NFMZ@976,COG0179@1,COG0179@2 NA|NA|NA Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase JOKFNDED_00775 1056512.D515_04867 1.1e-13 84.7 Vibrionales MA20_31720 Bacteria 1RKG9@1224,1S8MS@1236,1Y08G@135623,COG3672@1,COG3672@2 NA|NA|NA S Periplasmic Protein JOKFNDED_00777 1396418.BATQ01000070_gene751 1e-19 103.2 Verrucomicrobiae menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 2IU5W@203494,46V9A@74201,COG1575@1,COG1575@2 NA|NA|NA H UbiA prenyltransferase family JOKFNDED_00778 349741.Amuc_1816 1.5e-47 196.8 Verrucomicrobiae menC GO:0008150,GO:0040007 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 iNJ661.Rv0553,iSB619.SA_RS09080 Bacteria 2IUF3@203494,46X7I@74201,COG4948@1,COG4948@2 NA|NA|NA M Mandelate Racemase Muconate Lactonizing JOKFNDED_00779 1396141.BATP01000045_gene1745 2.5e-54 219.5 Verrucomicrobiae menE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0008150,GO:0008152,GO:0008756,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016043,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0022607,GO:0042180,GO:0042181,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576,GO:1901661,GO:1901663 4.2.1.113,6.2.1.26 ko:K01911,ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030,R04031 RC00004,RC00014,RC01053 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2354,iECSF_1327.ECSF_2141,iEcE24377_1341.EcE24377A_2556,iEcHS_1320.EcHS_A2406,iJN678.menE,iLF82_1304.LF82_1314,iNRG857_1313.NRG857_11465 Bacteria 2IUC3@203494,46XUP@74201,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme JOKFNDED_00780 1396418.BATQ01000141_gene3417 5.5e-111 407.9 Bacteria Bacteria COG0613@1,COG0613@2 NA|NA|NA Q PHP domain protein JOKFNDED_00781 1396418.BATQ01000155_gene2459 8.2e-181 640.2 Verrucomicrobiae trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITH7@203494,46S4I@74201,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I, N terminal region JOKFNDED_00782 1403819.BATR01000051_gene1542 3.1e-74 285.4 Verrucomicrobiae Bacteria 2IU55@203494,46SKU@74201,COG1235@1,COG1235@2 NA|NA|NA S Metallo-beta-lactamase superfamily JOKFNDED_00784 452637.Oter_3495 9.5e-28 131.0 Opitutae Bacteria 3K802@414999,46T9P@74201,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family JOKFNDED_00785 240016.ABIZ01000001_gene878 1.4e-15 88.2 Verrucomicrobia Bacteria 2AEIE@1,314DU@2,46WQ3@74201 NA|NA|NA JOKFNDED_00786 334545.CCMG01000008_gene726 2.1e-120 439.1 Rickettsiales ko:K07133 ko00000 Bacteria 1MWBT@1224,2U050@28211,47FW5@766,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) JOKFNDED_00787 452637.Oter_0644 5.8e-216 758.1 Opitutae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 3K7V5@414999,46SF0@74201,COG1074@1,COG1074@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily JOKFNDED_00789 1396141.BATP01000027_gene1078 3.7e-48 198.0 Bacteria Bacteria 31A0K@2,arCOG05203@1 NA|NA|NA JOKFNDED_00790 1396141.BATP01000047_gene3911 0.0 1082.4 Verrucomicrobiae Bacteria 2ITV9@203494,46STC@74201,COG4581@1,COG4581@2 NA|NA|NA L Domain of unknown function (DUF3516) JOKFNDED_00792 1123070.KB899260_gene2034 1.7e-220 772.7 Verrucomicrobiae Bacteria 2IV6M@203494,46UEW@74201,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family JOKFNDED_00793 1403819.BATR01000180_gene6023 1.9e-08 64.7 Verrucomicrobiae ko:K03821 ko00650,map00650 R04254 RC00004 ko00000,ko00001,ko01000 Bacteria 2IW1U@203494,46XJ2@74201,COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity JOKFNDED_00794 794903.OPIT5_25665 2.1e-09 70.1 Bacteria Bacteria 2DTGP@1,33K9B@2 NA|NA|NA JOKFNDED_00795 1403819.BATR01000087_gene2568 3.3e-33 148.3 Verrucomicrobiae MA20_05485 Bacteria 2IUPA@203494,46X6F@74201,COG5465@1,COG5465@2 NA|NA|NA S Putative bacterial sensory transduction regulator JOKFNDED_00796 1403819.BATR01000087_gene2567 2e-13 83.2 Verrucomicrobia ko:K08981 ko00000 Bacteria 46WSZ@74201,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain JOKFNDED_00799 497964.CfE428DRAFT_3820 3e-158 565.5 Bacteria 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria COG1858@1,COG1858@2 NA|NA|NA C electron transfer activity JOKFNDED_00800 497964.CfE428DRAFT_5080 2.4e-22 112.5 Verrucomicrobia Bacteria 29N11@1,344HT@2,46WBB@74201 NA|NA|NA JOKFNDED_00801 1396141.BATP01000003_gene5037 1e-116 427.2 Verrucomicrobiae Bacteria 2IV1G@203494,46UTF@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00802 1396141.BATP01000003_gene5036 7e-264 918.3 Verrucomicrobiae 3.1.4.46,3.2.1.78 ko:K01126,ko:K01218 ko00051,ko00564,ko02024,map00051,map00564,map02024 R01030,R01332,R01470 RC00017,RC00425,RC00467 ko00000,ko00001,ko01000 GH26 Bacteria 2IWPZ@203494,46TXW@74201,COG2931@1,COG2931@2,COG3299@1,COG3299@2,COG4733@1,COG4733@2,COG5267@1,COG5267@2 NA|NA|NA Q PA14 JOKFNDED_00804 1121403.AUCV01000031_gene2839 2.4e-48 199.5 Proteobacteria Bacteria 1RBMB@1224,2DKWY@1,30NX3@2 NA|NA|NA JOKFNDED_00805 1121403.AUCV01000031_gene2839 1.6e-44 186.8 Proteobacteria Bacteria 1RBMB@1224,2DKWY@1,30NX3@2 NA|NA|NA JOKFNDED_00808 1123070.KB899257_gene2292 9.3e-28 131.0 Verrucomicrobiae araC ko:K21701 ko00000,ko03000 Bacteria 2IUQB@203494,46T4M@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_00809 1396141.BATP01000022_gene422 5.1e-244 850.5 Verrucomicrobiae purF 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2ITSB@203494,46UKZ@74201,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine JOKFNDED_00810 1396141.BATP01000022_gene423 1.3e-121 443.0 Verrucomicrobiae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2ITTU@203494,46SJ4@74201,COG0150@1,COG0150@2 NA|NA|NA F AIR synthase related protein, N-terminal domain JOKFNDED_00811 1396418.BATQ01000138_gene3938 4.1e-77 294.7 Verrucomicrobiae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IV5H@203494,46T5R@74201,COG0047@1,COG0047@2 NA|NA|NA F CobB/CobQ-like glutamine amidotransferase domain JOKFNDED_00812 240016.ABIZ01000001_gene1938 4.9e-102 377.9 Verrucomicrobiae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IUEK@203494,46S8Y@74201,COG0046@1,COG0046@2 NA|NA|NA F involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate JOKFNDED_00813 530564.Psta_4378 8.6e-58 230.7 Planctomycetes Bacteria 2IXPZ@203682,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_00814 530564.Psta_4276 9.5e-28 129.8 Bacteria vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_00815 1403819.BATR01000164_gene5520 1.8e-82 312.8 Verrucomicrobiae yocS ko:K03453 ko00000 2.A.28 Bacteria 2IU81@203494,46YXM@74201,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) JOKFNDED_00816 1403819.BATR01000164_gene5521 2.3e-101 375.9 Verrucomicrobia Bacteria 46TVB@74201,COG3173@1,COG3173@2 NA|NA|NA S Phosphotransferase enzyme family JOKFNDED_00817 794903.OPIT5_15730 1.8e-61 242.7 Verrucomicrobia 4.1.2.20,4.1.2.52 ko:K01630,ko:K02510 ko00053,ko00350,ko01120,map00053,map00350,map01120 R01645,R01647,R02754,R03277 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 Bacteria 46V5P@74201,COG3836@1,COG3836@2 NA|NA|NA G HpcH/HpaI aldolase/citrate lyase family JOKFNDED_00818 1403819.BATR01000117_gene4033 1.4e-157 562.4 Verrucomicrobiae Bacteria 2IU34@203494,46UEJ@74201,COG1082@1,COG1082@2 NA|NA|NA G AP endonuclease family 2 C terminus JOKFNDED_00820 1123508.JH636440_gene2073 5.5e-11 73.6 Planctomycetes Bacteria 2J1MD@203682,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain JOKFNDED_00821 240016.ABIZ01000001_gene2649 1.7e-190 672.2 Verrucomicrobiae ywqF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 ko:K00012,ko:K00066 ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020 M00014,M00129,M00361,M00362 R00286,R00880 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU1R@203494,46S6E@74201,COG1004@1,COG1004@2 NA|NA|NA M UDP binding domain JOKFNDED_00822 240016.ABIZ01000001_gene2650 1e-179 637.1 Verrucomicrobiae CP_0756 ko:K04744 ko00000,ko02000 1.B.42.1 Bacteria 2ITQV@203494,46SJX@74201,COG1452@1,COG1452@2 NA|NA|NA M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane JOKFNDED_00823 1396418.BATQ01000117_gene4526 5.7e-32 144.8 Verrucomicrobiae lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_2567 Bacteria 2IU6J@203494,46SQN@74201,COG1043@1,COG1043@2 NA|NA|NA M Udp N-acetylglucosamine O-acyltransferase; Domain 2 JOKFNDED_00824 1396418.BATQ01000117_gene4524 1.3e-53 216.5 Verrucomicrobiae radC ko:K03630 ko00000 Bacteria 2IU7T@203494,46STQ@74201,COG2003@1,COG2003@2 NA|NA|NA L RadC-like JAB domain JOKFNDED_00825 1396418.BATQ01000091_gene5777 4.6e-127 461.5 Verrucomicrobiae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 2ITV2@203494,46SIQ@74201,COG0486@1,COG0486@2 NA|NA|NA J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 JOKFNDED_00826 1396141.BATP01000007_gene5658 9.7e-103 380.6 Verrucomicrobiae Bacteria 2IU14@203494,46U0B@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00827 240016.ABIZ01000001_gene1879 6e-118 431.8 Verrucomicrobiae Bacteria 2IWP0@203494,46Z2Y@74201,COG5330@1,COG5330@2 NA|NA|NA S SLA1 homology domain 1, SHD1 JOKFNDED_00828 243090.RB12068 1.5e-130 473.0 Planctomycetes Bacteria 2IXN8@203682,COG1520@1,COG1520@2 NA|NA|NA S serine threonine protein kinase afsK JOKFNDED_00829 1396418.BATQ01000157_gene2437 3e-48 200.3 Bacteria ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria COG0747@1,COG0747@2 NA|NA|NA E dipeptide transport JOKFNDED_00831 1296416.JACB01000026_gene3952 6.3e-176 625.5 Aquimarina ko:K13276 ko00000,ko01000,ko01002,ko03110 Bacteria 1I7A8@117743,2YKAC@290174,4NIPP@976,COG1858@1,COG1858@2,COG3209@1,COG3209@2,COG3291@1,COG3291@2,COG3391@1,COG3391@2,COG4733@1,COG4733@2,COG5276@1,COG5276@2 NA|NA|NA MP Cellulose binding domain JOKFNDED_00832 1403819.BATR01000032_gene1062 1.4e-55 223.0 Verrucomicrobiae 5.4.2.6 ko:K01838 ko00500,map00500 R02728,R11310 RC00408 ko00000,ko00001,ko01000 Bacteria 2IUCX@203494,46SWS@74201,COG0637@1,COG0637@2 NA|NA|NA S HAD-hyrolase-like JOKFNDED_00834 497964.CfE428DRAFT_3372 1.2e-55 222.6 Bacteria 2.6.1.98 ko:K13017 ko00520,map00520 R10141 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_00836 388467.A19Y_3367 5.4e-120 438.0 Oscillatoriales ykbA ko:K03294 ko00000 2.A.3.2 Bacteria 1G2GM@1117,1H9QG@1150,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease JOKFNDED_00838 1396141.BATP01000023_gene743 1.8e-48 198.7 Verrucomicrobiae Bacteria 2IVPR@203494,46VIW@74201,COG3871@1,COG3871@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase like JOKFNDED_00839 1396418.BATQ01000154_gene1020 1.1e-45 190.3 Verrucomicrobiae Bacteria 2IUX8@203494,46Z4H@74201,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein JOKFNDED_00840 1396418.BATQ01000016_gene4193 5e-15 87.0 Verrucomicrobiae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IUU4@203494,46TBG@74201,COG0360@1,COG0360@2 NA|NA|NA J Ribosomal protein S6 JOKFNDED_00841 111780.Sta7437_3103 4.6e-45 188.0 Pleurocapsales pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1G0D0@1117,3VJ60@52604,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis JOKFNDED_00843 1123070.KB899267_gene2476 3.6e-20 104.8 Bacteria aglS ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria COG0848@1,COG0848@2 NA|NA|NA U biopolymer transport protein JOKFNDED_00844 1123070.KB899267_gene2475 5.2e-22 110.9 Verrucomicrobiae exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUYI@203494,46W26@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_00846 1396418.BATQ01000145_gene3539 3.3e-13 82.0 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_00847 452637.Oter_1247 5.1e-10 70.5 Opitutae GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 Bacteria 3K8HF@414999,46XWT@74201,COG4118@1,COG4118@2 NA|NA|NA D positive regulation of growth JOKFNDED_00848 452637.Oter_1248 4.3e-29 134.4 Opitutae vapC ko:K07064 ko00000 Bacteria 3K8HY@414999,46XWY@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_00849 1123242.JH636435_gene1995 3.9e-127 461.8 Planctomycetes Bacteria 2IY2W@203682,COG5476@1,COG5476@2 NA|NA|NA S MlrC C-terminus JOKFNDED_00850 530564.Psta_1125 5.4e-57 228.4 Planctomycetes 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY02@203682,COG2706@1,COG2706@2 NA|NA|NA G COG2706 3-carboxymuconate cyclase JOKFNDED_00852 583355.Caka_2744 9.4e-165 586.3 Opitutae glnII 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 3K7II@414999,46UNZ@74201,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase JOKFNDED_00853 1396141.BATP01000004_gene5842 1.4e-107 396.4 Verrucomicrobiae ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 iYL1228.KPN_03597,ic_1306.c3945 Bacteria 2ITYJ@203494,46SKW@74201,COG0142@1,COG0142@2 NA|NA|NA H Polyprenyl synthetase JOKFNDED_00854 1396141.BATP01000003_gene4959 2.4e-13 81.3 Verrucomicrobiae tatA ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IURB@203494,46WPX@74201,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system JOKFNDED_00855 1403819.BATR01000104_gene3624 1.1e-61 243.8 Verrucomicrobiae Bacteria 2IUCM@203494,46Z38@74201,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family JOKFNDED_00856 1403819.BATR01000179_gene5988 0.0 1619.0 Verrucomicrobia Bacteria 46UES@74201,COG2319@1,COG2319@2 NA|NA|NA S WD40 repeats JOKFNDED_00858 1122138.AQUZ01000097_gene6902 1.7e-07 62.4 Actinobacteria hipB ko:K15773 ko00000,ko02048,ko03000 Bacteria 2GWW5@201174,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins JOKFNDED_00860 714943.Mucpa_4406 6.8e-25 120.6 Sphingobacteriia Bacteria 1IYZV@117747,4PC3N@976,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_00861 388467.A19Y_1168 3.2e-206 724.5 Oscillatoriales gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 1G0SD@1117,1H8CN@1150,COG0493@1,COG0493@2 NA|NA|NA E TIGRFAM glutamate synthases, NADH NADPH, small subunit JOKFNDED_00862 452637.Oter_0894 0.0 1409.0 Opitutae gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 3K7GP@414999,46U9T@74201,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E glutamate synthase JOKFNDED_00865 1396418.BATQ01000110_gene4789 3.3e-61 241.9 Verrucomicrobia yafV 3.5.1.3 ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 46T1B@74201,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase JOKFNDED_00867 1403819.BATR01000056_gene1760 2.1e-174 619.0 Verrucomicrobiae mdlB ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2ITQH@203494,46TV7@74201,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region JOKFNDED_00869 344747.PM8797T_25041 4e-49 201.8 Planctomycetes 5.1.3.22,5.3.1.5 ko:K01805,ko:K03079 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R00878,R01432,R03244 RC00376,RC00516,RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXXX@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_00873 1122222.AXWR01000018_gene2633 1.2e-239 836.3 Deinococcus-Thermus 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1WN70@1297,COG4096@1,COG4096@2 NA|NA|NA L Type I site-specific restriction-modification system, R (Restriction) subunit and related JOKFNDED_00874 710111.FraQA3DRAFT_4299 3.6e-46 192.6 Frankiales hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IRWB@201174,4EU9U@85013,COG0732@1,COG0732@2 NA|NA|NA L Type I restriction modification DNA specificity domain JOKFNDED_00875 330214.NIDE0139 1.5e-173 616.3 Nitrospirae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 3J15I@40117,COG0286@1,COG0286@2 NA|NA|NA V Product type e enzyme JOKFNDED_00877 1396418.BATQ01000020_gene5030 1.7e-140 506.9 Verrucomicrobiae fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2ITIY@203494,46UK0@74201,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase JOKFNDED_00878 452637.Oter_4081 3.8e-32 145.2 Opitutae braZ ko:K09792 ko00000 Bacteria 3K9GV@414999,46VBD@74201,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome C biogenesis protein transmembrane region JOKFNDED_00880 1396141.BATP01000022_gene260 3.4e-149 535.0 Verrucomicrobiae ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2ITW3@203494,46TZJ@74201,COG0348@1,COG0348@2 NA|NA|NA C 4Fe-4S dicluster domain JOKFNDED_00881 1396141.BATP01000022_gene263 6.9e-40 170.6 Verrucomicrobiae ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 2IUJ4@203494,46SVP@74201,COG2010@1,COG2010@2 NA|NA|NA C N-terminal domain of cytochrome oxidase-cbb3, FixP JOKFNDED_00883 1502851.FG93_02924 1.3e-64 253.4 Bradyrhizobiaceae ccoO 1.9.3.1 ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0145 Bacteria 1MXEY@1224,2TRGW@28211,3JUIE@41294,COG2993@1,COG2993@2 NA|NA|NA C Cytochrome C oxidase, mono-heme subunit/FixO JOKFNDED_00884 1197906.CAJQ02000023_gene2576 3.8e-92 344.4 Bradyrhizobiaceae ccoN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K00404,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144 Bacteria 1MU18@1224,2TR2C@28211,3JV5P@41294,COG3278@1,COG3278@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family JOKFNDED_00885 886293.Sinac_4637 3e-212 744.6 Planctomycetes Bacteria 2IXDG@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00886 886293.Sinac_0105 1.1e-09 71.2 Planctomycetes Bacteria 2DTCQ@1,2J1DV@203682,33JQY@2 NA|NA|NA JOKFNDED_00887 497964.CfE428DRAFT_5990 3e-57 228.4 Verrucomicrobia sigX ko:K03088 ko00000,ko03021 Bacteria 46W20@74201,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_00888 1123278.KB893444_gene1666 2e-30 138.7 Cytophagia Bacteria 2C87P@1,32H7J@2,47R39@768503,4NS7S@976 NA|NA|NA JOKFNDED_00889 1504981.KO116_2754 3.6e-21 108.2 Gammaproteobacteria yjoA Bacteria 1N153@1224,1SD8B@1236,COG2318@1,COG2318@2 NA|NA|NA S DinB family JOKFNDED_00890 1188252.AJYK01000068_gene199 9.9e-17 94.0 Vibrionales Bacteria 1RE1W@1224,1S59Q@1236,1XU3T@135623,COG3332@1,COG3332@2 NA|NA|NA S Transport and Golgi organisation 2 JOKFNDED_00891 583355.Caka_1928 2.3e-143 516.5 Verrucomicrobia 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 46UXZ@74201,COG0189@1,COG0189@2,COG0586@1,COG0586@2,COG1073@1,COG1073@2 NA|NA|NA HJ SNARE associated Golgi protein JOKFNDED_00892 497964.CfE428DRAFT_6357 3.2e-69 268.5 Verrucomicrobia Bacteria 46UGN@74201,COG3176@1,COG3176@2 NA|NA|NA S Acetyltransferase (GNAT) domain JOKFNDED_00893 926566.Terro_3830 6.2e-37 161.0 Acidobacteriia 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2JJGD@204432,3Y4YU@57723,COG0204@1,COG0204@2 NA|NA|NA I PFAM Phospholipid glycerol acyltransferase JOKFNDED_00894 1278073.MYSTI_07456 2.7e-53 215.3 Myxococcales msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1MVUS@1224,2WNTJ@28221,2YZKR@29,42NB7@68525,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine JOKFNDED_00895 1396418.BATQ01000075_gene626 4.9e-63 248.1 Verrucomicrobiae Bacteria 2IW4S@203494,46Z3W@74201,COG2706@1,COG2706@2 NA|NA|NA G 6-phosphogluconolactonase activity JOKFNDED_00896 1288963.ADIS_2906 3.4e-64 251.9 Cytophagia 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 47UJP@768503,4NMGK@976,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family JOKFNDED_00897 756067.MicvaDRAFT_2819 8.2e-74 284.6 Oscillatoriales Bacteria 1G554@1117,1HF7I@1150,COG0823@1,COG0823@2,COG2931@1,COG2931@2 NA|NA|NA QU PFAM Haemolysin-type calcium-binding repeat JOKFNDED_00898 497964.CfE428DRAFT_2285 3.5e-28 133.3 Verrucomicrobia Bacteria 2C7EB@1,347YC@2,46W4Z@74201 NA|NA|NA JOKFNDED_00899 1403819.BATR01000094_gene2977 7.9e-14 83.6 Verrucomicrobia hsp18 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 46WVG@74201,COG0071@1,COG0071@2 NA|NA|NA O Hsp20/alpha crystallin family JOKFNDED_00900 1396418.BATQ01000141_gene3415 7.1e-13 80.5 Verrucomicrobiae hspX GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IVVF@203494,46T3G@74201,COG0071@1,COG0071@2 NA|NA|NA O Hsp20/alpha crystallin family JOKFNDED_00902 1396141.BATP01000021_gene148 2.9e-58 233.0 Verrucomicrobiae msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 2IUM0@203494,46TM8@74201,COG0229@1,COG0229@2 NA|NA|NA O SelR domain JOKFNDED_00903 1237149.C900_03315 3.1e-76 291.6 Cytophagia yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 47JWX@768503,4NE8Y@976,COG0217@1,COG0217@2 NA|NA|NA K transcriptional regulatory protein JOKFNDED_00904 240016.ABIZ01000001_gene3949 6.1e-286 990.7 Bacteria ko:K02305,ko:K08738 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 Bacteria COG3474@1,COG3474@2 NA|NA|NA C electron transfer activity JOKFNDED_00905 1396141.BATP01000004_gene5913 1e-209 736.1 Verrucomicrobiae Bacteria 2IV5R@203494,46TG2@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_00906 1396141.BATP01000004_gene5914 1.6e-236 826.2 Verrucomicrobiae Bacteria 2IV5F@203494,46TII@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_00908 1396141.BATP01000030_gene3727 1.6e-151 542.7 Verrucomicrobiae norM ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2IU2M@203494,46UTM@74201,COG0534@1,COG0534@2 NA|NA|NA V MatE JOKFNDED_00909 794903.OPIT5_05750 5.3e-155 554.3 Opitutae sdcS ko:K03319,ko:K14445 ko00000,ko02000 2.A.47,2.A.47.1 Bacteria 3K8N7@414999,46UPI@74201,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region JOKFNDED_00910 240016.ABIZ01000001_gene5627 2.3e-28 131.7 Verrucomicrobiae Bacteria 2IVHH@203494,46XD3@74201,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family JOKFNDED_00911 344747.PM8797T_03064 2.1e-170 605.5 Bacteria Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_00912 344747.PM8797T_09619 2.9e-148 531.9 Planctomycetes Bacteria 2J53C@203682,COG1073@1,COG1073@2 NA|NA|NA S alpha beta JOKFNDED_00913 382464.ABSI01000016_gene740 5.1e-77 296.2 Bacteria ko:K13735 ko05100,map05100 ko00000,ko00001 Bacteria COG2982@1,COG2982@2,COG4932@1,COG4932@2 NA|NA|NA M Protein involved in outer membrane biogenesis JOKFNDED_00914 1396418.BATQ01000135_gene3630 1.6e-64 253.1 Verrucomicrobiae znuA ko:K02077,ko:K09815,ko:K11707 ko02010,map02010 M00242,M00244,M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2IVSM@203494,46TZH@74201,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic JOKFNDED_00915 240016.ABIZ01000001_gene5845 2.1e-46 191.8 Verrucomicrobiae glbO GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 ko:K06886 ko00000 Bacteria 2IUJC@203494,46X5K@74201,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin JOKFNDED_00916 1396418.BATQ01000064_gene1596 1.2e-43 184.5 Verrucomicrobiae Bacteria 2IU85@203494,46W4C@74201,COG4886@1,COG4886@2 NA|NA|NA S Planctomycete cytochrome C JOKFNDED_00918 1306174.JODP01000013_gene7805 9.9e-137 493.4 Actinobacteria pfp 2.7.1.90 ko:K00895 ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130 R00764,R02073 RC00017 ko00000,ko00001,ko01000 Bacteria 2GK6W@201174,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis JOKFNDED_00919 583355.Caka_0385 8.2e-102 376.7 Bacteria IV02_08645 ko:K07137 ko00000 Bacteria COG2509@1,COG2509@2 NA|NA|NA H 5-formyltetrahydrofolate cyclo-ligase activity JOKFNDED_00920 36331.EPrPI00000021209 4.5e-42 178.3 Pythiales Eukaryota 1MD6Y@121069,2CFGF@1,2RWD6@2759 NA|NA|NA S Codanin-1 C-terminus JOKFNDED_00921 497964.CfE428DRAFT_2431 1.1e-271 942.6 Verrucomicrobia ko:K09992 ko00000 Bacteria 46UMZ@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Cytochrome c JOKFNDED_00922 240016.ABIZ01000001_gene5685 1.2e-53 216.5 Verrucomicrobiae 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IURK@203494,46SKI@74201,COG0266@1,COG0266@2 NA|NA|NA L Formamidopyrimidine-DNA glycosylase H2TH domain JOKFNDED_00925 349741.Amuc_0140 9.3e-132 476.9 Verrucomicrobiae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN746.PP_0436,iLJ478.TM0478 Bacteria 2IWM1@203494,46S76@74201,COG0162@1,COG0162@2 NA|NA|NA J tRNA synthetases class I (W and Y) JOKFNDED_00926 382464.ABSI01000014_gene1430 1e-29 136.7 Verrucomicrobiae gcvR 1.1.1.3,1.1.1.399,1.1.1.95 ko:K00003,ko:K00058 ko00260,ko00270,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020 R01513,R01773,R01775 RC00031,RC00087 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IVUS@203494,46VWB@74201,COG2716@1,COG2716@2 NA|NA|NA E ACT domain JOKFNDED_00927 595460.RRSWK_04107 0.0 2003.0 Bacteria Bacteria 2DBSP@1,2ZAT9@2 NA|NA|NA JOKFNDED_00928 595460.RRSWK_04108 1.2e-145 524.6 Planctomycetes ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IYBK@203682,COG2304@1,COG2304@2 NA|NA|NA K von Willebrand factor, type A JOKFNDED_00929 595460.RRSWK_04109 3.5e-47 194.9 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_00932 3988.XP_002536121.1 1.6e-54 219.9 Eukaryota Eukaryota 28JZQ@1,2SAZ0@2759 NA|NA|NA JOKFNDED_00934 595460.RRSWK_01963 5.7e-17 94.0 Planctomycetes Bacteria 2IXCK@203682,COG0657@1,COG0657@2 NA|NA|NA I COG0657 Esterase lipase JOKFNDED_00935 706587.Desti_4248 9.2e-11 71.6 Deltaproteobacteria tdh 1.1.1.103 ko:K00060 ko00260,map00260 R01465 RC00525 ko00000,ko00001,ko01000 Bacteria 1MV9A@1224,2WM39@28221,42PCA@68525,COG1063@1,COG1063@2 NA|NA|NA C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate JOKFNDED_00936 595460.RRSWK_01821 1.1e-153 549.7 Planctomycetes kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 2IX0H@203682,COG0156@1,COG0156@2 NA|NA|NA H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA JOKFNDED_00937 1123070.KB899258_gene1910 8.9e-77 293.9 Verrucomicrobiae Bacteria 2IU9W@203494,46TD0@74201,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain JOKFNDED_00938 1123070.KB899248_gene220 1.5e-130 472.6 Verrucomicrobiae Bacteria 2IVQ8@203494,46V78@74201,COG4804@1,COG4804@2 NA|NA|NA S Protein of unknown function (DUF1016) JOKFNDED_00939 497964.CfE428DRAFT_3901 6.9e-236 823.5 Verrucomicrobia uvrD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 46S8H@74201,COG0210@1,COG0210@2 NA|NA|NA L PFAM UvrD REP helicase JOKFNDED_00940 1123070.KB899261_gene2141 5.7e-153 547.7 Verrucomicrobiae phoH ko:K07175 ko00000 Bacteria 2IU15@203494,46TI4@74201,COG1875@1,COG1875@2 NA|NA|NA T PIN domain JOKFNDED_00941 478741.JAFS01000002_gene230 3e-28 131.7 unclassified Verrucomicrobia wzb 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 37GX7@326457,46WFP@74201,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphatase family JOKFNDED_00943 497964.CfE428DRAFT_6232 1.3e-21 109.4 Verrucomicrobia Bacteria 46W19@74201,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver JOKFNDED_00945 521674.Plim_0571 1.1e-179 636.3 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_00946 1123070.KB899265_gene1862 4.9e-38 164.1 Verrucomicrobiae nikR ko:K07722 ko00000,ko03000 Bacteria 2IUN1@203494,46W5K@74201,COG0864@1,COG0864@2 NA|NA|NA K NikR C terminal nickel binding domain JOKFNDED_00947 382464.ABSI01000002_gene4383 1.8e-80 305.8 Verrucomicrobiae IV02_09290 ko:K09967 ko00000 Bacteria 2IU0M@203494,46V8Y@74201,COG3665@1,COG3665@2 NA|NA|NA S Domain of unknown function (DUF1989) JOKFNDED_00948 382464.ABSI01000002_gene4382 1.3e-92 345.9 Verrucomicrobiae ycgI ko:K09967 ko00000 Bacteria 2IU25@203494,46UWG@74201,COG3665@1,COG3665@2 NA|NA|NA S Domain of unknown function (DUF1989) JOKFNDED_00949 1470593.BW43_02852 1.7e-23 117.1 Bacteria Bacteria 2EJ0Q@1,33CRW@2 NA|NA|NA JOKFNDED_00952 83406.HDN1F_05650 3.6e-58 233.0 unclassified Gammaproteobacteria ycbB ko:K21470 ko00000,ko01002,ko01011 Bacteria 1J5U9@118884,1MV14@1224,1RQR7@1236,COG2989@1,COG2989@2 NA|NA|NA S protein conserved in bacteria JOKFNDED_00953 1396141.BATP01000039_gene1303 1.8e-80 305.8 Verrucomicrobiae ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU4W@203494,46U7Z@74201,COG0327@1,COG0327@2 NA|NA|NA S NIF3 (NGG1p interacting factor 3) JOKFNDED_00955 452637.Oter_0645 2.1e-139 503.4 Opitutae 3.6.4.12 ko:K16899 ko00000,ko01000,ko03400 Bacteria 3K85H@414999,46SDQ@74201,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily JOKFNDED_00958 1443665.JACA01000013_gene4287 1.5e-49 204.9 Aquimarina chiA 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 R01206,R02334 RC00467 ko00000,ko00001,ko01000 GH18 Bacteria 1I0PM@117743,2YHWT@290174,4NKW9@976,COG3227@1,COG3227@2,COG3291@1,COG3291@2,COG4733@1,COG4733@2 NA|NA|NA IQ Fibronectin type III domain JOKFNDED_00959 240016.ABIZ01000001_gene3605 5.6e-46 193.0 Verrucomicrobiae Bacteria 2IVU3@203494,46XG7@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein kinase domain JOKFNDED_00965 467661.RKLH11_2002 1.5e-64 252.3 unclassified Rhodobacteraceae ko:K09958 ko00000 Bacteria 1RA64@1224,2U5FW@28211,3ZICK@58840,COG3558@1,COG3558@2 NA|NA|NA S Response regulator receiver domain protein JOKFNDED_00966 1280953.HOC_04517 3.8e-22 111.7 Hyphomonadaceae mip Bacteria 1R84B@1224,2U42G@28211,440PX@69657,COG2128@1,COG2128@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity JOKFNDED_00967 452637.Oter_0294 1.9e-38 165.2 Bacteria Bacteria COG3370@1,COG3370@2 NA|NA|NA O peroxiredoxin activity JOKFNDED_00968 240016.ABIZ01000001_gene197 4.7e-44 184.1 Verrucomicrobia Bacteria 46VBZ@74201,COG3558@1,COG3558@2 NA|NA|NA S Domain of unknown function (DUF5069) JOKFNDED_00969 1403819.BATR01000019_gene632 9e-72 276.9 Verrucomicrobiae ko:K07006 ko00000 Bacteria 2IVR9@203494,46SQM@74201,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase JOKFNDED_00970 1403819.BATR01000104_gene3500 2.4e-79 302.4 Verrucomicrobia Bacteria 46TE2@74201,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family JOKFNDED_00971 1118153.MOY_12404 2.3e-30 139.0 Oceanospirillales yezE GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K16137 ko00000,ko03000 Bacteria 1NCEF@1224,1RQ8N@1236,1XKK9@135619,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family JOKFNDED_00972 857087.Metme_3572 1e-20 105.5 Gammaproteobacteria 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1NBW3@1224,1SECR@1236,COG1942@1,COG1942@2 NA|NA|NA S 4-oxalocrotonate tautomerase JOKFNDED_00973 570952.ATVH01000013_gene2719 1.6e-41 176.0 Rhodospirillales Bacteria 1RBG0@1224,2JTG8@204441,2U4DJ@28211,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family JOKFNDED_00975 1250232.JQNJ01000001_gene1156 6.9e-67 260.4 Flavobacteriia ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1HXRH@117743,4NG84@976,COG1573@1,COG1573@2 NA|NA|NA L Uracil DNA glycosylase superfamily JOKFNDED_00977 595460.RRSWK_00516 1.2e-32 146.7 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_00978 595460.RRSWK_00518 4.4e-44 184.5 Planctomycetes Bacteria 2IYUM@203682,COG2128@1,COG2128@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity JOKFNDED_00979 1122135.KB893135_gene673 1.5e-40 172.2 Alphaproteobacteria Bacteria 1MY7X@1224,2DMKA@1,2UA3T@28211,32S5N@2 NA|NA|NA JOKFNDED_00980 384765.SIAM614_17274 2.3e-29 135.6 Alphaproteobacteria Bacteria 1N0GC@1224,2UBRM@28211,COG3350@1,COG3350@2 NA|NA|NA S YHS domain protein JOKFNDED_00981 1142394.PSMK_27980 5e-97 361.7 Planctomycetes Bacteria 2J2JB@203682,COG1075@1,COG1075@2 NA|NA|NA S Lecithin:cholesterol acyltransferase JOKFNDED_00982 525897.Dbac_0341 8.5e-186 656.8 Desulfovibrionales merA Bacteria 1MU2U@1224,2M9MS@213115,2WJAJ@28221,42MBP@68525,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family JOKFNDED_00983 344747.PM8797T_00352 9.7e-61 240.4 Planctomycetes merA Bacteria 2IZA9@203682,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein JOKFNDED_00985 1396418.BATQ01000091_gene5783 2e-95 355.9 Verrucomicrobiae kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K02467,ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 iAPECO1_1312.APECO1_3818,iECABU_c1320.ECABU_c29780,iECED1_1282.ECED1_3157,iECH74115_1262.ECH74115_4519,iECOK1_1307.ECOK1_3081,iECS88_1305.ECS88_2971,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSF_1195.SF2731,iSFxv_1172.SFxv_3550,iS_1188.S2922,iUTI89_1310.UTI89_C3070,iYL1228.KPN_03607,iZ_1308.Z4560,ic_1306.c3262 Bacteria 2ITHA@203494,46S8G@74201,COG0517@1,COG0517@2,COG0794@1,COG0794@2 NA|NA|NA M SIS domain JOKFNDED_00986 1396141.BATP01000039_gene1265 3.2e-10 70.5 Verrucomicrobiae dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 2ITT1@203494,46SNK@74201,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII JOKFNDED_00991 1168059.KB899087_gene695 3.2e-22 114.0 Xanthobacteraceae ko:K19231 ko00000,ko02000 1.B.12 Bacteria 1MU92@1224,2TSB7@28211,3F0R0@335928,COG3210@1,COG3210@2,COG3468@1,COG3468@2,COG4625@1,COG4625@2 NA|NA|NA U Autotransporter beta-domain JOKFNDED_00992 756272.Plabr_0478 4e-65 254.2 Planctomycetes 3.6.3.38 ko:K07214,ko:K09689 ko02010,map02010 M00249 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101 Bacteria 2IWXM@203682,COG2382@1,COG2382@2 NA|NA|NA P esterase JOKFNDED_00993 497964.CfE428DRAFT_4764 2e-122 445.7 Verrucomicrobia uvrA2 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 46SAF@74201,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate JOKFNDED_00994 278957.ABEA03000127_gene3615 1.3e-16 94.4 Opitutae yxaI Bacteria 3K8J3@414999,46Z5U@74201,COG1714@1,COG1714@2 NA|NA|NA S RDD family JOKFNDED_00995 62928.azo2926 3.3e-08 65.1 Proteobacteria 3.4.21.96 ko:K01361 ko00000,ko01000,ko01002,ko03110 Bacteria 1QVCP@1224,COG3103@1,COG3103@2 NA|NA|NA T Sh3 type 3 domain protein JOKFNDED_00997 5286.M7WNS4 1.2e-25 124.0 Pucciniomycotina GO:0001726,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005856,GO:0005886,GO:0005933,GO:0005935,GO:0005938,GO:0006810,GO:0006897,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0008289,GO:0009987,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0022607,GO:0030029,GO:0030036,GO:0030427,GO:0030479,GO:0030863,GO:0030864,GO:0031252,GO:0031253,GO:0031256,GO:0031344,GO:0032587,GO:0035091,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0051015,GO:0051017,GO:0051128,GO:0051179,GO:0051234,GO:0051641,GO:0051666,GO:0060491,GO:0061572,GO:0061645,GO:0065007,GO:0071840,GO:0071944,GO:0097435,GO:0098590,GO:0098657,GO:0099568,GO:0120025,GO:0120032,GO:0120035,GO:0120038,GO:1900027 ko:K20523 ko00000,ko04131 Fungi 2YCKI@29000,38FCU@33154,3NWAM@4751,3UXUS@5204,COG2930@1,KOG1843@2759 NA|NA|NA S Las17-binding protein actin regulator JOKFNDED_00998 497964.CfE428DRAFT_4366 5.8e-106 391.3 Verrucomicrobia Bacteria 46TRS@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_01000 1239962.C943_02131 4.1e-09 67.4 Cytophagia Bacteria 47JTD@768503,4NHIB@976,COG2307@1,COG2307@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. JOKFNDED_01002 43989.cce_4451 1.2e-17 96.3 Cyanothece Bacteria 1GM96@1117,2C3DY@1,2ZXVH@2,3KJVP@43988 NA|NA|NA S Transmembrane family 220, helix JOKFNDED_01003 1403819.BATR01000007_gene237 3.7e-107 395.2 Verrucomicrobiae 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 2IVGJ@203494,46V55@74201,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase JOKFNDED_01004 382464.ABSI01000009_gene3918 5.9e-33 149.1 Verrucomicrobiae Bacteria 2AX2S@1,2IWCF@203494,31P13@2,46XPX@74201 NA|NA|NA S Protease prsW family JOKFNDED_01005 1396141.BATP01000032_gene4425 4.2e-54 218.4 Bacteria bshB1 ko:K01463 ko00000,ko01000 Bacteria COG2120@1,COG2120@2 NA|NA|NA S N-acetylglucosaminylinositol deacetylase activity JOKFNDED_01006 1396141.BATP01000032_gene4424 1.8e-93 349.7 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_01007 1227739.Hsw_1967 1.5e-82 313.5 Cytophagia sypQ Bacteria 47KET@768503,4NEG0@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 JOKFNDED_01008 1396141.BATP01000058_gene2056 1.2e-67 264.2 Bacteria ko:K02847 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 Bacteria COG3307@1,COG3307@2 NA|NA|NA M -O-antigen JOKFNDED_01009 1396141.BATP01000020_gene25 2.2e-138 499.2 Verrucomicrobiae Bacteria 2IWKV@203494,46UXW@74201,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase JOKFNDED_01010 1396141.BATP01000020_gene26 2.3e-75 290.4 Verrucomicrobiae ywqD 2.7.10.1 ko:K08252,ko:K13661,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 2IVHF@203494,46YXA@74201,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM Chain length determinant protein JOKFNDED_01011 1123070.KB899256_gene2241 5.2e-66 258.1 Verrucomicrobiae ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IU5B@203494,46SY0@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_01012 240016.ABIZ01000001_gene1394 2.2e-27 128.6 Verrucomicrobiae exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUJ8@203494,46T1K@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_01015 1403819.BATR01000118_gene4114 2.6e-18 98.6 Verrucomicrobia Bacteria 2E4YE@1,32ZSA@2,46WYD@74201 NA|NA|NA JOKFNDED_01017 278957.ABEA03000135_gene1781 2.2e-210 739.2 Opitutae 3.6.4.13 ko:K03579 ko00000,ko01000 Bacteria 3K7J2@414999,46TMT@74201,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase C-terminal JOKFNDED_01018 1403819.BATR01000066_gene1998 6.2e-164 584.3 Verrucomicrobiae Bacteria 2IV3M@203494,46ZIT@74201,COG3206@1,COG3206@2 NA|NA|NA M Domain of unknown function (DUF4407) JOKFNDED_01020 1461577.CCMH01000040_gene251 5.9e-06 60.5 Flavobacteriia ompA ko:K03286 ko00000,ko02000 1.B.6 Bacteria 1HZH8@117743,4NHTP@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family JOKFNDED_01023 1396141.BATP01000036_gene3832 8.7e-17 94.0 Bacteria Bacteria 2CI51@1,317KW@2 NA|NA|NA JOKFNDED_01024 1396418.BATQ01000099_gene5560 8e-239 833.2 Verrucomicrobiae pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2ITWE@203494,46SBP@74201,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction JOKFNDED_01026 497964.CfE428DRAFT_2941 3e-79 302.4 Verrucomicrobia rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 46SPT@74201,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA JOKFNDED_01027 497964.CfE428DRAFT_6469 4.6e-112 411.8 Verrucomicrobia dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 46SKM@74201,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication JOKFNDED_01028 1396418.BATQ01000070_gene742 5.4e-41 174.1 Verrucomicrobiae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUF8@203494,46SYE@74201,COG0359@1,COG0359@2 NA|NA|NA J Ribosomal protein L9, N-terminal domain JOKFNDED_01029 1396141.BATP01000005_gene5939 5.5e-61 240.7 Verrucomicrobiae Bacteria 2IUAS@203494,46SWU@74201,COG1225@1,COG1225@2 NA|NA|NA O Redoxin JOKFNDED_01030 1403819.BATR01000016_gene521 8.8e-139 500.7 Verrucomicrobiae ppaC 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 2ITG8@203494,46UKX@74201,COG1227@1,COG1227@2 NA|NA|NA C DHHA2 JOKFNDED_01031 1396141.BATP01000004_gene5857 5.6e-21 107.5 Verrucomicrobiae Bacteria 2BVMR@1,2IWBK@203494,33H8Q@2,46WSY@74201 NA|NA|NA S AP2 domain JOKFNDED_01032 497964.CfE428DRAFT_3898 2.5e-97 362.8 Verrucomicrobia 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 46SHP@74201,COG0265@1,COG0265@2 NA|NA|NA O PFAM peptidase S1 and S6 chymotrypsin Hap JOKFNDED_01033 497964.CfE428DRAFT_3353 1.2e-134 486.5 Verrucomicrobia moeB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 ko:K03148,ko:K21029,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 46SGF@74201,COG0476@1,COG0476@2,COG0607@1,COG0607@2 NA|NA|NA H UBA THIF-type NAD FAD binding protein JOKFNDED_01035 573065.Astex_0652 5.7e-16 89.7 Caulobacterales ygaP Bacteria 1N6NN@1224,2KHDC@204458,2UFC1@28211,32YCZ@2,COG0607@1 NA|NA|NA P Protein of unknown function (DUF2892) JOKFNDED_01037 879310.HMPREF9162_1147 1.9e-31 142.9 Firmicutes Bacteria 1TRPP@1239,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A domain protein JOKFNDED_01039 240016.ABIZ01000001_gene2504 5.9e-88 332.0 Verrucomicrobiae 3.1.3.1 ko:K01077,ko:K07004 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2IVUV@203494,46U16@74201,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity JOKFNDED_01041 59538.XP_005969533.1 6e-27 128.6 Mammalia OVCH1 ko:K01362 ko00000,ko01000,ko01002 Mammalia 38GGI@33154,3BHVY@33208,3CW68@33213,3JDQW@40674,483YP@7711,48WJ5@7742,COG5640@1,KOG3627@2759,KOG3714@1,KOG3714@2759 NA|NA|NA E Trypsin-like serine protease JOKFNDED_01042 1396418.BATQ01000184_gene2608 1.1e-231 809.7 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46UFD@74201,COG2319@1,COG2319@2,COG5492@1,COG5492@2 NA|NA|NA N WD domain, G-beta repeat JOKFNDED_01043 240016.ABIZ01000001_gene5711 2.6e-56 226.5 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46UFD@74201,COG2319@1,COG2319@2,COG5492@1,COG5492@2 NA|NA|NA N WD domain, G-beta repeat JOKFNDED_01045 1123242.JH636435_gene1648 3.2e-58 232.3 Planctomycetes Bacteria 2IZUP@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_01046 1396141.BATP01000023_gene585 6.4e-50 203.8 Verrucomicrobiae Bacteria 2IUFP@203494,46T1U@74201,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain JOKFNDED_01047 794903.OPIT5_13095 7.2e-18 97.1 Opitutae sufE ko:K02426 ko00000 Bacteria 3K88I@414999,46W04@74201,COG2166@1,COG2166@2 NA|NA|NA S Fe-S metabolism JOKFNDED_01048 497964.CfE428DRAFT_1462 7.5e-64 250.8 Verrucomicrobia ko:K03424 ko00000,ko01000 Bacteria 46SRB@74201,COG0084@1,COG0084@2 NA|NA|NA L PFAM TatD-related deoxyribonuclease JOKFNDED_01049 1125863.JAFN01000001_gene1948 3.5e-58 233.0 Deltaproteobacteria 2.7.13.3 ko:K02482,ko:K14986 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1RCM9@1224,2WIZU@28221,42MC4@68525,COG2984@1,COG2984@2,COG4191@1,COG4191@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase A domain protein JOKFNDED_01050 1396418.BATQ01000140_gene3204 1.5e-114 419.9 Verrucomicrobiae Bacteria 2IU14@203494,46U0B@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_01051 240016.ABIZ01000001_gene1879 1.3e-123 450.7 Verrucomicrobiae Bacteria 2IWP0@203494,46Z2Y@74201,COG5330@1,COG5330@2 NA|NA|NA S SLA1 homology domain 1, SHD1 JOKFNDED_01052 1328313.DS2_08957 2.7e-33 150.2 Alteromonadaceae Bacteria 1PN9U@1224,1RRFX@1236,466BK@72275,COG3712@1,COG3712@2 NA|NA|NA PT Concanavalin A-like lectin/glucanases superfamily JOKFNDED_01053 452637.Oter_3158 1.2e-18 100.1 Verrucomicrobia rfaY ko:K03088 ko00000,ko03021 Bacteria 46W3R@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_01054 768671.ThimaDRAFT_1665 3.2e-38 165.6 Chromatiales Bacteria 1RBPU@1224,1S24P@1236,1WY62@135613,COG3698@1,COG3698@2 NA|NA|NA S Phosphodiester glycosidase JOKFNDED_01055 1396141.BATP01000033_gene4247 5.1e-257 894.0 Verrucomicrobiae Bacteria 2IV7X@203494,46XAT@74201,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase JOKFNDED_01056 1403819.BATR01000114_gene3945 3.7e-162 578.2 Verrucomicrobiae 3.1.6.1,3.1.6.8 ko:K01130,ko:K01134 ko00140,ko00600,ko04142,map00140,map00600,map04142 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 2IU4V@203494,46UET@74201,COG3119@1,COG3119@2 NA|NA|NA P C-terminal region of aryl-sulfatase JOKFNDED_01058 118166.JH976537_gene4234 7.9e-134 486.1 Oscillatoriales 3.1.4.46 ko:K01126,ko:K07093 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1GQ3P@1117,1HI0H@1150,COG3211@1,COG3211@2,COG4222@1,COG4222@2 NA|NA|NA Q Glycerophosphoryl diester phosphodiesterase family JOKFNDED_01059 1144932.ATTF01000019_gene805 6.8e-19 101.7 unclassified Alphaproteobacteria degP GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2TQPZ@28211,4BPCV@82117,COG0265@1,COG0265@2 NA|NA|NA O Belongs to the peptidase S1C family JOKFNDED_01060 1120963.KB894504_gene1859 5.9e-13 80.9 Gammaproteobacteria Bacteria 1NFAN@1224,1SFXI@1236,2E3EZ@1,32YDW@2 NA|NA|NA JOKFNDED_01062 794903.OPIT5_13020 1.8e-36 160.2 Verrucomicrobia 3.1.3.6,3.1.4.16 ko:K01119,ko:K20276 ko00230,ko00240,ko02024,map00230,map00240,map02024 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 46VHC@74201,COG1404@1,COG1404@2,COG2755@1,COG2755@2 NA|NA|NA O lipolytic protein G-D-S-L family JOKFNDED_01063 1396141.BATP01000039_gene1272 7.5e-263 915.2 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2,COG3204@1,COG3204@2,COG3540@1,COG3540@2,COG4222@1,COG4222@2 NA|NA|NA L pilus organization JOKFNDED_01064 1123070.KB899248_gene61 1.9e-146 525.8 Verrucomicrobiae proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iYO844.BSU13130 Bacteria 2ITYN@203494,46SGA@74201,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate JOKFNDED_01065 1396418.BATQ01000056_gene167 7.9e-66 257.3 Verrucomicrobiae proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_3198 Bacteria 2IU7N@203494,46SWM@74201,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate JOKFNDED_01067 794903.OPIT5_12250 2.8e-125 455.3 Opitutae Bacteria 3K9X1@414999,46XWK@74201,COG4861@1,COG4861@2 NA|NA|NA S Transcriptional regulator, AbiEi antitoxin, Type IV TA system JOKFNDED_01068 335543.Sfum_3181 6.2e-45 188.0 Syntrophobacterales Bacteria 1PKM5@1224,2A9IN@1,2MSDV@213462,2WY5H@28221,30YR0@2,4328D@68525 NA|NA|NA JOKFNDED_01069 314230.DSM3645_26029 6.8e-180 636.7 Planctomycetes Bacteria 2IXE5@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_01070 497964.CfE428DRAFT_3369 5e-76 291.6 Verrucomicrobia rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 46U3A@74201,COG1234@1,COG1234@2 NA|NA|NA S Beta-lactamase superfamily domain JOKFNDED_01071 1033802.SSPSH_000725 1.6e-33 149.4 Gammaproteobacteria nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 1RI3B@1224,1S6HR@1236,COG0494@1,COG0494@2 NA|NA|NA L DNA mismatch repair protein MutT JOKFNDED_01073 1396141.BATP01000007_gene5670 1.6e-24 119.0 Verrucomicrobiae Bacteria 2IW1E@203494,46T2S@74201,COG2331@1,COG2331@2 NA|NA|NA S Putative regulatory protein JOKFNDED_01074 1123368.AUIS01000035_gene74 1.3e-35 156.0 Gammaproteobacteria Bacteria 1N05H@1224,1S8SJ@1236,COG1959@1,COG1959@2 NA|NA|NA K Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity JOKFNDED_01075 314230.DSM3645_18486 2.1e-33 149.1 Planctomycetes Bacteria 2BUZP@1,2IZVI@203682,32QC7@2 NA|NA|NA S Protein of unknown function (DUF3365) JOKFNDED_01076 1120970.AUBZ01000029_gene1051 3.6e-25 121.7 Gammaproteobacteria glbN GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 ko:K03406,ko:K06886 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1QBDE@1224,1S9FC@1236,COG2346@1,COG2346@2 NA|NA|NA C Group 1 truncated hemoglobin JOKFNDED_01077 344747.PM8797T_00142 2e-48 199.9 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity JOKFNDED_01078 240016.ABIZ01000001_gene1298 1.9e-170 605.5 Verrucomicrobiae Bacteria 2IV6W@203494,46UBZ@74201,COG0477@1,COG2814@2 NA|NA|NA EGP Sugar (and other) transporter JOKFNDED_01079 497964.CfE428DRAFT_5434 2e-93 349.4 Verrucomicrobia Bacteria 46TSD@74201,COG3391@1,COG3391@2 NA|NA|NA C Membrane JOKFNDED_01080 765912.Thimo_0462 1.2e-36 159.8 Chromatiales Bacteria 1N1KS@1224,1S4QZ@1236,1WY2C@135613,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_01082 1123073.KB899244_gene397 7.2e-20 104.8 Xanthomonadales Bacteria 1QEAT@1224,1TAVS@1236,1X8YF@135614,2ARAV@1,31GKV@2 NA|NA|NA JOKFNDED_01083 1120792.JAFV01000001_gene3008 1.2e-49 203.8 Methylocystaceae dgoK 2.7.1.58 ko:K00883 ko00052,ko01100,map00052,map01100 M00552 R03387 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWGX@1224,2TTG8@28211,370DZ@31993,COG3734@1,COG3734@2 NA|NA|NA G 2-keto-3-deoxy-galactonokinase JOKFNDED_01084 344747.PM8797T_09724 1.9e-152 545.8 Planctomycetes 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 2IXP4@203682,COG2355@1,COG2355@2 NA|NA|NA E Zn-dependent dipeptidase, microsomal dipeptidase JOKFNDED_01085 195250.CM001776_gene3317 4.3e-23 114.0 Cyanobacteria ko:K03892 ko00000,ko03000 Bacteria 1G8BZ@1117,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor JOKFNDED_01086 857087.Metme_1115 1.6e-68 266.2 Methylococcales pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MVXP@1224,1RNK7@1236,1XGZY@135618,COG0226@1,COG0226@2 NA|NA|NA P PBP superfamily domain JOKFNDED_01087 472759.Nhal_2980 1.7e-56 226.5 Chromatiales ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MVKP@1224,1RQXJ@1236,1WWUX@135613,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane JOKFNDED_01088 1173027.Mic7113_1640 8e-72 277.3 Oscillatoriales pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1G1S1@1117,1HH64@1150,COG0581@1,COG0581@2 NA|NA|NA P PFAM Binding-protein-dependent transport system inner membrane component JOKFNDED_01089 472759.Nhal_2978 2.2e-81 308.9 Chromatiales pstB 3.6.3.27,3.6.3.55 ko:K02036,ko:K02068,ko:K06857 ko02010,map02010 M00186,M00211,M00222 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.2,3.A.1.6.4,3.A.1.7 Bacteria 1MU16@1224,1RNUF@1236,1WWM1@135613,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system JOKFNDED_01090 583355.Caka_2256 6.9e-79 301.2 Verrucomicrobia ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 46T78@74201,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P JOKFNDED_01091 1403819.BATR01000087_gene2543 7.1e-47 194.9 Verrucomicrobiae ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 2IVDD@203494,46T78@74201,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P JOKFNDED_01092 880073.Calab_3575 1.4e-69 269.6 unclassified Bacteria Bacteria 2NP9R@2323,COG0745@1,COG0745@2 NA|NA|NA K COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain JOKFNDED_01093 404380.Gbem_2673 5.3e-81 308.5 Desulfuromonadales Bacteria 1MW8M@1224,2WJAU@28221,42QF7@68525,43VY7@69541,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_01094 391596.PBAL39_22335 3.2e-22 112.8 Sphingobacteriia Bacteria 1INZ6@117747,4NH4Z@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_01098 240016.ABIZ01000001_gene5793 5.2e-253 880.6 Verrucomicrobiae Bacteria 2ITI2@203494,46UHZ@74201,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor, type A JOKFNDED_01099 240016.ABIZ01000001_gene5794 2.5e-148 532.7 Verrucomicrobiae Bacteria 2IU3K@203494,46TD3@74201,COG1572@1,COG1572@2 NA|NA|NA S Aerotolerance regulator N-terminal JOKFNDED_01100 1396418.BATQ01000009_gene3847 4.3e-108 397.9 Verrucomicrobiae Bacteria 2ITRG@203494,46UUS@74201,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 JOKFNDED_01101 1396418.BATQ01000009_gene3846 3.4e-146 524.6 Verrucomicrobiae ko:K03924,ko:K07452 ko00000,ko01000,ko02048 Bacteria 2IWKP@203494,46U40@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_01102 32057.KB217483_gene9954 2.4e-13 84.0 Cyanobacteria Bacteria 1G6AK@1117,2E6C0@1,330ZT@2 NA|NA|NA JOKFNDED_01103 240016.ABIZ01000001_gene4087 9.4e-51 206.5 Verrucomicrobiae bcp 1.11.1.15,2.7.7.42,2.7.7.89 ko:K00982,ko:K03564 ko00000,ko01000 Bacteria 2IUE3@203494,46SYK@74201,COG1225@1,COG1225@2 NA|NA|NA O Redoxin JOKFNDED_01104 1403819.BATR01000171_gene5859 1.1e-123 450.3 Bacteria rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria COG0265@1,COG0265@2,COG0750@1,COG0750@2 NA|NA|NA M metalloendopeptidase activity JOKFNDED_01105 1254432.SCE1572_47090 8e-258 896.3 Myxococcales yjhG GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0050401,GO:0071704,GO:0072329,GO:1901575 4.2.1.82 ko:K22396 ko00040,map00040 R02429 RC00543 ko00000,ko00001,ko01000 Bacteria 1MUTQ@1224,2WJB7@28221,2YWT1@29,42N3P@68525,COG0129@1,COG0129@2 NA|NA|NA H Belongs to the IlvD Edd family JOKFNDED_01106 1396141.BATP01000001_gene5348 1.2e-77 296.6 Verrucomicrobiae MA20_14845 4.2.1.141 ko:K14259 ko00040,map00040 R09186 RC00429 ko00000,ko00001,ko01000 Bacteria 2IUA6@203494,46S9N@74201,COG3970@1,COG3970@2 NA|NA|NA S Fumarylacetoacetate (FAA) hydrolase family JOKFNDED_01107 1396418.BATQ01000130_gene4862 2.3e-40 172.6 Verrucomicrobiae Bacteria 2IVUP@203494,46SVG@74201,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family JOKFNDED_01109 643473.KB235931_gene5014 2.4e-46 192.6 Nostocales Bacteria 1GK3C@1117,1HT6N@1161,2BQVF@1,32JSB@2 NA|NA|NA S Putative MetA-pathway of phenol degradation JOKFNDED_01110 583355.Caka_2750 5.7e-92 344.4 Opitutae mntD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K11709 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 3K9T1@414999,46YRP@74201,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family JOKFNDED_01111 1237149.C900_04906 1.1e-30 139.8 Cytophagia Bacteria 2AFHA@1,315HT@2,47VEE@768503,4NQ5F@976 NA|NA|NA S 23S rRNA-intervening sequence protein JOKFNDED_01112 583355.Caka_2749 6.4e-92 344.4 Bacteria mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K03709,ko:K09819,ko:K11708 ko02010,map02010 M00243,M00319 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.15 Bacteria COG1108@1,COG1108@2,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor JOKFNDED_01113 240016.ABIZ01000001_gene3863 3.1e-47 195.7 Verrucomicrobiae gyrA 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2ITMM@203494,46SBE@74201,COG0188@1,COG0188@2 NA|NA|NA L DNA Topoisomerase IV JOKFNDED_01115 497964.CfE428DRAFT_6009 1.9e-131 475.7 Verrucomicrobia frvX 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 46SM3@74201,COG1363@1,COG1363@2 NA|NA|NA G peptidase M42 family protein JOKFNDED_01116 1123242.JH636437_gene5974 1e-146 526.9 Planctomycetes Bacteria 2IYM3@203682,COG3356@1,COG3356@2 NA|NA|NA S PFAM Neutral alkaline nonlysosomal ceramidase JOKFNDED_01117 313628.LNTAR_21860 1.2e-184 654.1 Bacteria 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA G pyrroloquinoline quinone binding JOKFNDED_01118 1403819.BATR01000005_gene172 3.6e-57 228.4 Verrucomicrobiae Bacteria 2IVPP@203494,46STY@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_01119 1123242.JH636434_gene4955 1.5e-181 642.5 Planctomycetes Bacteria 2IYHF@203682,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family JOKFNDED_01120 237368.SCABRO_00288 5.6e-39 167.2 Planctomycetes Bacteria 2DNV7@1,2J4XF@203682,32ZAW@2 NA|NA|NA S PD-(D/E)XK nuclease superfamily JOKFNDED_01123 240016.ABIZ01000001_gene1555 9.2e-11 73.2 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01124 1121904.ARBP01000006_gene3699 3.7e-84 318.5 Cytophagia 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47YPG@768503,4PM6P@976,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_01125 240016.ABIZ01000001_gene4436 7.2e-218 763.8 Verrucomicrobiae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IV6Y@203494,46USC@74201,COG0507@1,COG0507@2 NA|NA|NA L Helix-hairpin-helix containing domain JOKFNDED_01126 1123070.KB899253_gene1060 4.6e-16 91.7 Verrucomicrobiae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2IUIB@203494,46T75@74201,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit JOKFNDED_01127 240016.ABIZ01000001_gene4281 2.3e-67 262.7 Verrucomicrobiae rfaF 2.3.1.241,2.7.1.167,2.7.7.70 ko:K02517,ko:K02843,ko:K03272 ko00540,ko01100,map00540,map01100 M00060,M00064,M00080 R05146,R05644,R05646 RC00002,RC00037,RC00039,RC00078 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 2IUNU@203494,46SSR@74201,COG0859@1,COG0859@2,COG1560@1,COG1560@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) JOKFNDED_01129 1403819.BATR01000164_gene5649 2.4e-09 68.6 Verrucomicrobiae 2.1.1.80,2.7.13.3,3.1.1.61 ko:K02030,ko:K03407,ko:K07679,ko:K13924 ko02020,ko02030,ko05133,map02020,map02030,map05133 M00236,M00477,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035 3.A.1.3 Bacteria 2IWNI@203494,46UM4@74201,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T CHASE3 domain JOKFNDED_01131 1128421.JAGA01000002_gene1090 6.1e-18 96.7 Bacteria Bacteria 2BZBR@1,32YH6@2 NA|NA|NA JOKFNDED_01134 1121904.ARBP01000001_gene5603 2.4e-142 511.9 Cytophagia Bacteria 47KZS@768503,4NEC6@976,COG0673@1,COG0673@2 NA|NA|NA S PFAM Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_01135 1131269.AQVV01000044_gene1782 2.4e-11 75.5 Bacteria soxS 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria COG2143@1,COG2143@2 NA|NA|NA O COG2143 Thioredoxin-related protein JOKFNDED_01136 344747.PM8797T_11651 2e-136 492.7 Planctomycetes 3.1.6.13 ko:K01136 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00078 R07812,R07821 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXXP@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_01137 1396418.BATQ01000163_gene1986 1.2e-163 583.2 Verrucomicrobiae dinG GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 2ITJT@203494,46SCS@74201,COG1199@1,COG1199@2 NA|NA|NA L HELICc2 JOKFNDED_01139 1396418.BATQ01000170_gene2646 5.8e-89 334.3 Verrucomicrobiae nagA 3.5.1.25,3.5.99.6 ko:K01443,ko:K02564 ko00520,ko01100,ko01130,map00520,map01100,map01130 R00765,R02059 RC00163,RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 2IU36@203494,46SRF@74201,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family JOKFNDED_01140 857087.Metme_0403 4.6e-52 211.8 Gammaproteobacteria Bacteria 1NHGM@1224,1SHCF@1236,COG2227@1,COG2227@2 NA|NA|NA H PFAM Methyltransferase type 11 JOKFNDED_01141 1396141.BATP01000022_gene406 2.1e-54 218.8 Verrucomicrobiae Bacteria 2IW4C@203494,46VNM@74201,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_01142 497964.CfE428DRAFT_3903 5.7e-146 524.6 Verrucomicrobia malQ 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 Bacteria 46SX0@74201,COG1640@1,COG1640@2 NA|NA|NA G PFAM glycoside hydrolase family 77 JOKFNDED_01143 1396418.BATQ01000133_gene4037 7.5e-143 513.5 Verrucomicrobiae mdh GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITGY@203494,46SC4@74201,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate JOKFNDED_01147 215803.DB30_1057 3.5e-35 156.4 Myxococcales Bacteria 1QAMF@1224,2A747@1,2WZH9@28221,2Z255@29,30VZX@2,43E29@68525 NA|NA|NA JOKFNDED_01149 768671.ThimaDRAFT_3824 9.2e-56 224.2 Chromatiales merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1RDSJ@1224,1S42P@1236,1X252@135613,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance JOKFNDED_01150 1396418.BATQ01000014_gene4348 1.2e-42 179.9 Verrucomicrobia ko:K03088 ko00000,ko03021 Bacteria 46W6X@74201,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor JOKFNDED_01151 1396418.BATQ01000075_gene627 3.7e-73 282.0 Verrucomicrobia Bacteria 46V3J@74201,COG2133@1,COG2133@2 NA|NA|NA G Methane oxygenase PmoA JOKFNDED_01152 1247963.JPHU01000012_gene875 1e-51 210.3 Alphaproteobacteria trmJ GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.200,3.5.1.19,6.1.1.16 ko:K01883,ko:K02533,ko:K08281,ko:K15396 ko00760,ko00970,ko01100,map00760,map00970,map01100 M00359,M00360 R01268,R03650 RC00055,RC00100,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1N47Y@1224,2TS8J@28211,COG0565@1,COG0565@2 NA|NA|NA J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA JOKFNDED_01154 497964.CfE428DRAFT_0159 1.9e-49 201.8 Bacteria Bacteria COG3011@1,COG3011@2 NA|NA|NA CH Protein conserved in bacteria JOKFNDED_01155 886293.Sinac_2446 1e-216 759.6 Planctomycetes ko:K06978 ko00000 Bacteria 2IYPJ@203682,COG1506@1,COG1506@2,COG2936@1,COG2936@2 NA|NA|NA E X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain JOKFNDED_01156 1403819.BATR01000098_gene3287 2.7e-14 87.0 Verrucomicrobiae Bacteria 2EZMG@1,2IU6Q@203494,33SSM@2,46UUT@74201 NA|NA|NA JOKFNDED_01158 1396141.BATP01000009_gene2652 3.6e-71 275.0 Verrucomicrobiae yqjF ko:K09166 ko00000 Bacteria 2IUBS@203494,46VHU@74201,COG3361@1,COG3361@2 NA|NA|NA S Uncharacterized conserved protein (COG2071) JOKFNDED_01159 391625.PPSIR1_37309 2.6e-78 299.7 Myxococcales 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1MV70@1224,2WZ3T@28221,2Z19K@29,42ZJK@68525,COG1858@1,COG1858@2 NA|NA|NA C COG1858 Cytochrome c peroxidase JOKFNDED_01160 452637.Oter_0518 2.3e-182 646.4 Bacteria Bacteria COG4888@1,COG4888@2 NA|NA|NA G ASPIC UnbV domain protein JOKFNDED_01163 1396418.BATQ01000141_gene3380 4.5e-78 297.7 Verrucomicrobia glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 46V4W@74201,COG0580@1,COG0580@2 NA|NA|NA G Major intrinsic protein JOKFNDED_01164 96561.Dole_3012 1.1e-73 283.9 Desulfobacterales corA GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1MX09@1224,2MI8N@213118,2WJMJ@28221,42NS9@68525,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions JOKFNDED_01165 667632.KB890185_gene479 9.2e-72 277.3 Burkholderiaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1KD3X@119060,1MU9N@1224,2VMGN@28216,COG0332@1,COG0332@2 NA|NA|NA I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal JOKFNDED_01166 667632.KB890185_gene481 5.7e-70 271.2 Betaproteobacteria gumP Bacteria 1QPNG@1224,2VQW5@28216,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily JOKFNDED_01167 935866.JAER01000006_gene3273 1.1e-90 340.5 Propionibacteriales Bacteria 2HZ7W@201174,4DQSN@85009,COG1541@1,COG1541@2 NA|NA|NA H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) JOKFNDED_01168 1403819.BATR01000130_gene4637 4e-75 288.5 Verrucomicrobiae ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IU8I@203494,46TTR@74201,COG2304@1,COG2304@2 NA|NA|NA S Protein of unknown function (DUF1194) JOKFNDED_01169 497964.CfE428DRAFT_3460 4.4e-79 302.8 Verrucomicrobia batB ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 46SP8@74201,COG0457@1,COG0457@2,COG2304@1,COG2304@2 NA|NA|NA J von Willebrand factor (vWF) type A domain JOKFNDED_01172 1121904.ARBP01000002_gene6675 4.1e-51 209.1 Bacteroidetes yddG ko:K03201,ko:K13613 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko01004,ko01008,ko02044 3.A.7 Bacteria 4PKBQ@976,COG3209@1,COG3209@2,COG3420@1,COG3420@2,COG5644@1,COG5644@2 NA|NA|NA H endopeptidase inhibitor activity JOKFNDED_01173 1396141.BATP01000016_gene2777 1.5e-186 659.1 Verrucomicrobiae asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iSDY_1059.SDY_2327 Bacteria 2ITHF@203494,46TN6@74201,COG0017@1,COG0017@2 NA|NA|NA J tRNA synthetases class II (D, K and N) JOKFNDED_01174 864069.MicloDRAFT_00010740 2e-30 139.0 Proteobacteria yxeL ko:K00680 ko00000,ko01000 Bacteria 1QUB5@1224,COG0454@1,COG0456@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase JOKFNDED_01175 1142394.PSMK_24400 6.7e-36 158.7 Planctomycetes Bacteria 2IXAF@203682,COG2133@1,COG2133@2 NA|NA|NA G glucose sorbosone JOKFNDED_01176 1121904.ARBP01000003_gene6415 1.1e-162 580.1 Cytophagia Bacteria 47JYR@768503,4NHH7@976,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase JOKFNDED_01177 382464.ABSI01000010_gene3738 1.9e-85 323.6 Verrucomicrobiae ampH GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008360,GO:0008658,GO:0009056,GO:0009057,GO:0009253,GO:0016787,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031406,GO:0033218,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044238,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0097159,GO:0140096,GO:1901135,GO:1901136,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901681 3.4.16.4 ko:K18988 ko00000,ko01000,ko01002,ko01011 Bacteria 2IUVM@203494,46VJ9@74201,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase JOKFNDED_01178 1396418.BATQ01000085_gene1078 7.7e-251 873.6 Bacteria spoVAD ko:K06406 ko00000 Bacteria COG0304@1,COG0304@2 NA|NA|NA I 3-oxoacyl-[acyl-carrier-protein] synthase activity JOKFNDED_01179 240016.ABIZ01000001_gene1555 4.3e-64 251.9 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01180 1209072.ALBT01000012_gene3263 5.7e-37 161.8 Cellvibrio ywoF Bacteria 1FHZW@10,1R91N@1224,1RZ4P@1236,COG3420@1,COG3420@2 NA|NA|NA P Periplasmic copper-binding protein (NosD) JOKFNDED_01181 1396141.BATP01000030_gene3641 1.7e-65 256.1 Verrucomicrobiae yfcA GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0044464,GO:0050896,GO:0071944 ko:K07090,ko:K11312 ko00000 Bacteria 2IV00@203494,46V74@74201,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE JOKFNDED_01182 335543.Sfum_2876 3e-126 459.5 Proteobacteria ywoF Bacteria 1R94C@1224,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats JOKFNDED_01183 1519464.HY22_11920 2.1e-62 246.9 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_01184 1403819.BATR01000094_gene2939 6.6e-188 663.7 Verrucomicrobiae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 2ITJ9@203494,46W51@74201,COG0516@1,COG0516@2 NA|NA|NA F IMP dehydrogenase / GMP reductase domain JOKFNDED_01185 1396418.BATQ01000055_gene269 1.2e-192 679.5 Verrucomicrobiae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 2ITUH@203494,46SIW@74201,COG0519@1,COG0519@2 NA|NA|NA F GMP synthase C terminal domain JOKFNDED_01186 794903.OPIT5_06705 1.8e-146 526.9 Opitutae ybaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03455 ko00000 2.A.37 Bacteria 3K8Q4@414999,46UN8@74201,COG1226@1,COG1226@2,COG4651@1,COG4651@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family JOKFNDED_01187 118168.MC7420_1908 1.6e-35 157.5 Oscillatoriales 3.4.21.53 ko:K04076,ko:K04770 ko00000,ko01000,ko01002 Bacteria 1G1IM@1117,1H9XD@1150,COG1067@1,COG1067@2 NA|NA|NA O AAA ATPase domain JOKFNDED_01188 1173264.KI913949_gene2806 8.2e-07 62.4 Oscillatoriales Bacteria 1G0N0@1117,1HEV3@1150,COG0457@1,COG0457@2 NA|NA|NA S PFAM Tetratricopeptide JOKFNDED_01194 1396141.BATP01000025_gene980 4.6e-67 261.2 Verrucomicrobia Bacteria 46V5W@74201,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon JOKFNDED_01195 1096546.WYO_1422 4.8e-29 134.4 Methylobacteriaceae fhbA 1.14.12.17 ko:K05916 ko05132,map05132 ko00000,ko00001,ko01000 Bacteria 1JW3I@119045,1QVJP@1224,2U5M6@28211,COG1017@1,COG1017@2 NA|NA|NA C Globin JOKFNDED_01196 1396141.BATP01000025_gene978 1.7e-65 256.9 Bacteria 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG5002@1,COG5002@2 NA|NA|NA T protein histidine kinase activity JOKFNDED_01197 1396418.BATQ01000186_gene2166 1e-19 103.2 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_01199 497964.CfE428DRAFT_2311 2.9e-54 219.5 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46VAM@74201,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_01200 931627.MycrhDRAFT_2003 3e-187 661.8 Mycobacteriaceae Bacteria 23FE6@1762,2I9HI@201174,COG3866@1,COG3866@2,COG4932@1,COG4932@2 NA|NA|NA GM domain protein JOKFNDED_01201 240016.ABIZ01000001_gene181 6.2e-195 686.8 Verrucomicrobia Bacteria 46UNH@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_01203 1088721.NSU_1794 1.6e-13 83.2 Alphaproteobacteria Bacteria 1NVHG@1224,28PWR@1,2URVD@28211,2ZCGZ@2 NA|NA|NA JOKFNDED_01204 204669.Acid345_3047 1.4e-35 156.8 Acidobacteriia cusF ko:K07152,ko:K07810 ko02020,map02020 ko00000,ko00001,ko03029 2.A.6.1.4 Bacteria 2JHX0@204432,3Y5CC@57723,COG1999@1,COG1999@2,COG5569@1,COG5569@2 NA|NA|NA S Copper binding periplasmic protein CusF JOKFNDED_01205 478741.JAFS01000002_gene875 3e-28 132.1 unclassified Verrucomicrobia ypmQ ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 37GTT@326457,46VZB@74201,COG1999@1,COG1999@2 NA|NA|NA S SCO1/SenC JOKFNDED_01207 886293.Sinac_6139 1.5e-202 712.2 Planctomycetes Bacteria 2J2G0@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_01208 886293.Sinac_6140 4.4e-285 987.6 Planctomycetes Bacteria 2IXBU@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_01211 497964.CfE428DRAFT_0928 4.6e-15 88.2 Bacteria lolA ko:K03634 ko00000 Bacteria COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) JOKFNDED_01212 1396141.BATP01000007_gene5594 9.1e-102 378.3 Verrucomicrobiae hpnN ko:K07003 ko00000 Bacteria 2IV36@203494,46TC6@74201,COG4258@1,COG4258@2 NA|NA|NA S MMPL family JOKFNDED_01213 1469613.JT55_03440 3e-08 64.7 Alphaproteobacteria Bacteria 1N2WB@1224,2C112@1,2UC3U@28211,32SUT@2 NA|NA|NA S ATP synthase JOKFNDED_01214 1396141.BATP01000039_gene1243 2.5e-283 981.5 Verrucomicrobiae mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 Bacteria 2ITUY@203494,46SCK@74201,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity JOKFNDED_01215 1210884.HG799462_gene8124 7.2e-67 260.4 Planctomycetes Bacteria 2J3XD@203682,COG4186@1,COG4186@2 NA|NA|NA S nucleotidyltransferase activity JOKFNDED_01216 566466.NOR53_2474 1.2e-12 81.3 Gammaproteobacteria Bacteria 1NAWD@1224,1SE88@1236,2ECI4@1,336GB@2 NA|NA|NA S PcfJ-like protein JOKFNDED_01217 1143323.M787_0823 1.1e-11 76.3 Chlamydiae trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2JG8T@204428,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family JOKFNDED_01218 1396418.BATQ01000047_gene6179 7.3e-37 162.2 Verrucomicrobiae tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2ITNJ@203494,46T26@74201,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes JOKFNDED_01219 1396141.BATP01000030_gene3574 4.5e-17 93.6 Verrucomicrobiae Bacteria 2DFNJ@1,2IUSJ@203494,2ZSFW@2,46WS2@74201 NA|NA|NA S PurA ssDNA and RNA-binding protein JOKFNDED_01220 1403819.BATR01000008_gene242 5.7e-70 271.2 Verrucomicrobiae yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 Bacteria 2IU44@203494,46TP9@74201,COG1561@1,COG1561@2 NA|NA|NA S Domain of unknown function (DUF1732) JOKFNDED_01221 1396141.BATP01000025_gene909 1.4e-51 209.1 Verrucomicrobiae Bacteria 2IUGC@203494,46VKC@74201,COG2947@1,COG2947@2 NA|NA|NA S EVE domain JOKFNDED_01222 1123070.KB899261_gene2127 1.6e-94 353.2 Verrucomicrobiae sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K07033,ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2ITRN@203494,46S8S@74201,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) JOKFNDED_01223 1303692.SFUL_1344 1.1e-09 70.9 Actinobacteria ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,COG0601@1,COG0601@2 NA|NA|NA EP PFAM binding-protein-dependent transport systems inner membrane component JOKFNDED_01224 411469.EUBHAL_01266 7.6e-09 68.2 Eubacteriaceae nikC ko:K02034,ko:K15586 ko02010,ko02024,map02010,map02024 M00239,M00440 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TP4R@1239,2489T@186801,25WAU@186806,COG1173@1,COG1173@2 NA|NA|NA P ABC transporter, permease protein JOKFNDED_01225 1206741.BAFX01000109_gene7456 3e-26 125.9 Nocardiaceae ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4FUG8@85025,COG1123@1,COG4172@2 NA|NA|NA P Belongs to the ABC transporter superfamily JOKFNDED_01226 395961.Cyan7425_4883 1.8e-62 246.5 Cyanobacteria sun 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 1G2G7@1117,COG0144@1,COG0144@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family JOKFNDED_01227 1123070.KB899250_gene623 4.1e-123 448.0 Verrucomicrobiae mrp ko:K03593 ko00000,ko03029,ko03036 Bacteria 2ITW9@203494,46SAV@74201,COG0489@1,COG0489@2 NA|NA|NA D Iron-sulfur cluster assembly protein JOKFNDED_01229 886293.Sinac_6706 5.2e-12 79.0 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2J0M9@203682,COG3291@1,COG3291@2 NA|NA|NA M Domain of unknown function (DUF4394) JOKFNDED_01230 497964.CfE428DRAFT_4974 5.1e-74 284.6 Verrucomicrobia yfjR 1.1.1.31,1.1.1.60,1.1.1.79 ko:K00020,ko:K00042,ko:K18121 ko00280,ko00630,ko00650,ko01100,ko01120,ko01200,map00280,map00630,map00650,map01100,map01120,map01200 R00465,R01745,R01747,R05066,R09281 RC00042,RC00087,RC00099 ko00000,ko00001,ko01000 Bacteria 46U4D@74201,COG2084@1,COG2084@2 NA|NA|NA I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase JOKFNDED_01231 497964.CfE428DRAFT_4975 2.3e-36 159.5 Verrucomicrobia ygfZ GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 46T24@74201,COG0354@1,COG0354@2 NA|NA|NA S Belongs to the GcvT family JOKFNDED_01232 1396418.BATQ01000044_gene6479 2.4e-22 112.8 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_01233 1396418.BATQ01000044_gene6479 1.7e-23 116.7 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_01234 1403819.BATR01000164_gene5527 7e-153 547.0 Verrucomicrobia Bacteria 46TRW@74201,COG3391@1,COG3391@2 NA|NA|NA S NHL repeat JOKFNDED_01237 1396141.BATP01000060_gene4735 1.7e-76 292.7 Verrucomicrobiae Bacteria 2IVSS@203494,46VIZ@74201,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain JOKFNDED_01238 1403819.BATR01000130_gene4602 8.3e-34 150.2 Verrucomicrobiae Bacteria 2IVW6@203494,46WBI@74201,COG0454@1,COG0456@2 NA|NA|NA K Cyclic nucleotide-monophosphate binding domain JOKFNDED_01239 240016.ABIZ01000001_gene1251 1.2e-35 156.0 Verrucomicrobia Bacteria 46VNB@74201,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain JOKFNDED_01240 240016.ABIZ01000001_gene3023 4.2e-70 271.6 Verrucomicrobiae trpC GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.20,5.3.1.24 ko:K01609,ko:K01696,ko:K13498 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03508,R03509 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2494,iJN746.PP_0422,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 2ITZZ@203494,46V9B@74201,COG0134@1,COG0134@2 NA|NA|NA E Indole-3-glycerol phosphate synthase JOKFNDED_01242 1396141.BATP01000023_gene709 7.2e-41 174.5 Verrucomicrobiae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 2ITXU@203494,46SYY@74201,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase (PrmA) JOKFNDED_01243 1396418.BATQ01000176_gene2695 9e-83 313.9 Verrucomicrobiae pliT Bacteria 2IU5X@203494,46U4H@74201,COG4956@1,COG4956@2 NA|NA|NA S Large family of predicted nucleotide-binding domains JOKFNDED_01244 240016.ABIZ01000001_gene5609 7.3e-155 554.7 Verrucomicrobiae Bacteria 2IV1H@203494,46UXD@74201,COG2319@1,COG2319@2 NA|NA|NA S Protein of unknown function (DUF1549) JOKFNDED_01245 1403819.BATR01000045_gene1313 4.8e-150 537.7 Verrucomicrobiae Bacteria 2IU14@203494,46U0B@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_01247 240016.ABIZ01000001_gene3606 8.1e-272 943.0 Verrucomicrobiae glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700,ko:K17734 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 2ITSF@203494,46SH5@74201,COG0296@1,COG0296@2 NA|NA|NA G Alpha amylase, C-terminal all-beta domain JOKFNDED_01248 1396141.BATP01000039_gene1283 8.1e-139 500.4 Verrucomicrobiae rumA 2.1.1.190,2.1.1.35 ko:K03215,ko:K15331 ko00000,ko01000,ko03009,ko03016 Bacteria 2ITST@203494,46SYJ@74201,COG2265@1,COG2265@2 NA|NA|NA J tRNA (Uracil-5-)-methyltransferase JOKFNDED_01250 583355.Caka_1182 7.9e-60 238.0 Opitutae Bacteria 3K9G2@414999,46TD6@74201,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family JOKFNDED_01252 1463881.KL591004_gene4058 2.9e-15 90.5 Actinobacteria 3.6.4.12 ko:K02314,ko:K17680 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03029,ko03032 Bacteria 2I62I@201174,COG0305@1,COG0305@2 NA|NA|NA L Protein of unknown function (DUF3987) JOKFNDED_01255 314230.DSM3645_07805 4.7e-59 235.0 Planctomycetes Bacteria 2IXCK@203682,COG0657@1,COG0657@2 NA|NA|NA I COG0657 Esterase lipase JOKFNDED_01257 530564.Psta_2516 7.5e-109 401.4 Planctomycetes Bacteria 2IZEP@203682,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_01258 1266925.JHVX01000008_gene334 4.9e-47 193.7 Nitrosomonadales ko:K06996 ko00000 Bacteria 1N7Q5@1224,2VT7E@28216,373CD@32003,COG3324@1,COG3324@2 NA|NA|NA C glyoxalase bleomycin resistance protein dioxygenase JOKFNDED_01259 497964.CfE428DRAFT_3994 1.4e-103 382.9 Verrucomicrobia 3.1.1.11 ko:K01051 ko00040,ko01100,map00040,map01100 M00081 R02362 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria 46UM6@74201,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family JOKFNDED_01260 445961.IW15_17940 1e-20 107.5 Flavobacteriia Bacteria 1I3PG@117743,2BXMB@1,31ZJM@2,4NR0I@976 NA|NA|NA JOKFNDED_01262 886293.Sinac_3870 1.9e-142 512.7 Planctomycetes Bacteria 2IXH3@203682,COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase A JOKFNDED_01263 472759.Nhal_1468 9.9e-38 162.5 Chromatiales Bacteria 1N75D@1224,1SC8G@1236,1WYIJ@135613,COG3636@1,COG3636@2 NA|NA|NA K addiction module antidote protein JOKFNDED_01264 443143.GM18_0052 2.4e-28 131.3 Desulfuromonadales Bacteria 1N74C@1224,2WRI9@28221,42V2I@68525,43VGH@69541,COG3657@1,COG3657@2 NA|NA|NA S TIGRFAM Addiction module killer protein JOKFNDED_01265 886293.Sinac_2798 0.0 1130.5 Planctomycetes Bacteria 2IX5D@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_01266 497964.CfE428DRAFT_4359 1.1e-99 369.8 Verrucomicrobia MA20_18405 Bacteria 46W5T@74201,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase superfamily JOKFNDED_01267 1123242.JH636434_gene4617 1.6e-46 192.6 Bacteria Bacteria COG1225@1,COG1225@2 NA|NA|NA O peroxiredoxin activity JOKFNDED_01268 886293.Sinac_2799 4.7e-189 667.5 Planctomycetes Bacteria 2J4VG@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_01269 1142394.PSMK_20550 1.5e-16 92.4 Bacteria Bacteria 2CBRY@1,33DAH@2 NA|NA|NA JOKFNDED_01270 661478.OP10G_1529 1.2e-130 473.8 Bacteria Bacteria COG4805@1,COG4805@2 NA|NA|NA S Bacterial protein of unknown function (DUF885) JOKFNDED_01271 1396141.BATP01000027_gene1070 6.1e-234 817.4 Verrucomicrobiae ko:K02305,ko:K08738 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 Bacteria 2IVI1@203494,46UC5@74201,COG2133@1,COG2133@2,COG3474@1,COG3474@2 NA|NA|NA CG Cytochrome c JOKFNDED_01273 240016.ABIZ01000001_gene5847 1.5e-81 309.7 Verrucomicrobiae rarD ko:K05786 ko00000,ko02000 2.A.7.7 Bacteria 2IVMW@203494,46V11@74201,COG2962@1,COG2962@2 NA|NA|NA S EamA-like transporter family JOKFNDED_01274 886293.Sinac_2799 1.9e-195 688.7 Planctomycetes Bacteria 2J4VG@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_01275 1396141.BATP01000005_gene5990 3.8e-43 181.8 Verrucomicrobiae Bacteria 2IWH1@203494,46XSJ@74201,COG4185@1,COG4185@2 NA|NA|NA S zeta toxin JOKFNDED_01276 448385.sce3297 1.6e-14 87.0 Proteobacteria ko:K07287 ko00000,ko02000 1.B.33.1 Bacteria 1NFSN@1224,COG3317@1,COG3317@2 NA|NA|NA M Carbohydrate esterase, sialic acid-specific acetylesterase JOKFNDED_01277 756272.Plabr_0104 2.6e-91 342.4 Planctomycetes Bacteria 2IXCK@203682,COG0657@1,COG0657@2 NA|NA|NA I COG0657 Esterase lipase JOKFNDED_01279 1403819.BATR01000120_gene4238 1.5e-115 422.9 Verrucomicrobiae rlmM GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 ko:K06968 ko00000,ko01000,ko03009 Bacteria 2IVCF@203494,46XBS@74201,COG2933@1,COG2933@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily JOKFNDED_01280 351016.RAZWK3B_01830 7.7e-60 236.9 Roseobacter Bacteria 1RD42@1224,2P4VM@2433,2U3NV@28211,COG4337@1,COG4337@2 NA|NA|NA S protein conserved in bacteria JOKFNDED_01282 1396141.BATP01000032_gene4409 9.8e-76 290.8 Verrucomicrobiae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2ITJJ@203494,46SAY@74201,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain JOKFNDED_01283 1403819.BATR01000033_gene1108 8e-120 437.2 Verrucomicrobia ko:K07004 ko00000 Bacteria 46TT4@74201,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase JOKFNDED_01284 1121920.AUAU01000019_gene2586 6.7e-77 293.9 Acidobacteria cobB ko:K12410 ko00000,ko01000 Bacteria 3Y4T9@57723,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form JOKFNDED_01285 1396418.BATQ01000012_gene4394 1.2e-136 493.0 Verrucomicrobiae 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2IVXN@203494,46SCF@74201,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_01286 756272.Plabr_0264 3.7e-117 428.7 Planctomycetes Bacteria 2IXCB@203682,COG1331@1,COG1331@2 NA|NA|NA O Pectic acid lyase JOKFNDED_01289 497964.CfE428DRAFT_0153 5e-07 61.6 Verrucomicrobia ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 46SVS@74201,COG1450@1,COG1450@2,COG4219@1,COG4219@2 NA|NA|NA KT BlaR1 peptidase M56 JOKFNDED_01290 1396141.BATP01000032_gene4332 4.6e-56 224.6 Verrucomicrobiae Bacteria 2IU7U@203494,46SNA@74201,COG1028@1,COG1028@2 NA|NA|NA IQ RmlD substrate binding domain JOKFNDED_01292 439497.RR11_205 1.4e-81 309.7 Ruegeria sigW15 ko:K03088 ko00000,ko03021 Bacteria 1PFZE@1224,2V99Z@28211,4NDPF@97050,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_01295 1396418.BATQ01000133_gene4031 8.5e-37 161.0 Verrucomicrobiae 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IURC@203494,46WYP@74201,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family JOKFNDED_01296 251221.35213975 1.3e-28 132.9 Cyanobacteria ko:K02348 ko00000 Bacteria 1G6TQ@1117,COG2153@1,COG2153@2 NA|NA|NA S PFAM Acetyltransferase (GNAT) family JOKFNDED_01297 1403819.BATR01000104_gene3488 1.1e-95 356.7 Verrucomicrobiae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2ITTM@203494,46SNS@74201,COG0331@1,COG0331@2 NA|NA|NA I Acyl transferase domain JOKFNDED_01298 1089547.KB913013_gene4423 1.2e-35 156.8 Cytophagia ygjQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 ko:K03748 ko00000 Bacteria 47MWP@768503,4NNQS@976,COG2949@1,COG2949@2 NA|NA|NA S DUF218 domain JOKFNDED_01299 1403819.BATR01000002_gene16 2.3e-187 662.1 Verrucomicrobiae mdlB ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2ITQH@203494,46TV7@74201,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region JOKFNDED_01300 1396418.BATQ01000157_gene2417 6.7e-31 140.2 Verrucomicrobia 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 46T40@74201,COG0251@1,COG0251@2 NA|NA|NA J endoribonuclease L-PSP JOKFNDED_01301 1396141.BATP01000003_gene5165 1.1e-24 119.0 Verrucomicrobiae feoA ko:K04758 ko00000,ko02000 Bacteria 2IWG5@203494,46ZGK@74201,COG1918@1,COG1918@2 NA|NA|NA P FeoA domain JOKFNDED_01302 1396141.BATP01000003_gene5166 2.7e-227 795.0 Verrucomicrobiae feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 2ITUZ@203494,46SH4@74201,COG0370@1,COG0370@2 NA|NA|NA P Ferrous iron transport protein B C terminus JOKFNDED_01303 1396141.BATP01000007_gene5563 2.5e-126 459.9 Verrucomicrobiae Bacteria 2IVBI@203494,46UJG@74201,COG2304@1,COG2304@2,COG3210@1,COG3210@2 NA|NA|NA U Aerotolerance regulator N-terminal JOKFNDED_01304 1396141.BATP01000007_gene5562 1.1e-142 514.6 Verrucomicrobiae Bacteria 2IVT4@203494,46UJN@74201,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A domain JOKFNDED_01305 1396141.BATP01000007_gene5561 4e-51 210.7 Bacteria recN GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria COG0497@1,COG0497@2 NA|NA|NA L DNA recombination JOKFNDED_01306 1396141.BATP01000007_gene5560 2.7e-106 392.1 Verrucomicrobiae Bacteria 2IVRA@203494,46TZQ@74201,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase JOKFNDED_01308 497964.CfE428DRAFT_4414 1.1e-65 256.5 Verrucomicrobia lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 46T11@74201,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate JOKFNDED_01309 521674.Plim_2265 3.4e-38 166.8 Planctomycetes 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXV5@203682,COG1716@1,COG1716@2,COG2114@1,COG2114@2 NA|NA|NA T PFAM Adenylyl cyclase class-3 4 guanylyl cyclase JOKFNDED_01310 1403819.BATR01000153_gene5139 5.5e-40 172.9 Verrucomicrobiae Bacteria 2IVU3@203494,46XG7@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein kinase domain JOKFNDED_01311 497964.CfE428DRAFT_1015 1.4e-243 849.4 Verrucomicrobia Bacteria 46UND@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_01312 1396418.BATQ01000133_gene4039 2e-192 678.7 Verrucomicrobia Bacteria 46Z34@74201,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_01315 751945.Theos_0333 7.2e-10 70.5 Deinococcus-Thermus Bacteria 1WKHU@1297,2DNBX@1,32WPC@2 NA|NA|NA S PIN domain JOKFNDED_01318 452637.Oter_1808 2.6e-66 259.2 Opitutae ko:K13572 ko00000,ko03051 Bacteria 3K846@414999,46VG3@74201,COG2378@1,COG2378@2 NA|NA|NA K WYL domain JOKFNDED_01319 395493.BegalDRAFT_2258 1.2e-24 120.6 Thiotrichales ko:K13888 M00709 ko00000,ko00002,ko02000 8.A.1 Bacteria 1PFQI@1224,1RWE5@1236,46378@72273,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_01320 987059.RBXJA2T_15158 1.3e-19 102.1 unclassified Burkholderiales 4.1.3.27 ko:K01658,ko:K07010 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1KK6K@119065,1MV8E@1224,2VMMI@28216,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 JOKFNDED_01321 1396141.BATP01000002_gene4824 2.1e-12 79.3 Verrucomicrobiae pilW-2 ko:K02456,ko:K02650,ko:K02672 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IUWN@203494,46WJ1@74201,COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif JOKFNDED_01322 240016.ABIZ01000001_gene4556 4.6e-145 521.2 Verrucomicrobiae pilC ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2ITIH@203494,46S8P@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_01323 240016.ABIZ01000001_gene4557 8.2e-198 696.8 Verrucomicrobiae gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2ITMV@203494,46UFR@74201,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretion system (T2SS), protein E, N-terminal domain JOKFNDED_01324 1403819.BATR01000181_gene6139 5.5e-178 630.9 Verrucomicrobiae gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IU2P@203494,46SDR@74201,COG2804@1,COG2804@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_01325 203122.Sde_1211 2.6e-45 189.5 Alteromonadaceae yafK Bacteria 1MXY6@1224,1RPXT@1236,468BA@72275,COG3034@1,COG3034@2 NA|NA|NA S ErfK YbiS YcfS YnhG family protein JOKFNDED_01326 1396141.BATP01000047_gene3937 1.2e-118 433.0 Verrucomicrobiae mtnP GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2684 Bacteria 2ITPF@203494,46UP8@74201,COG0005@1,COG0005@2 NA|NA|NA F Phosphorylase superfamily JOKFNDED_01327 1396141.BATP01000047_gene3938 3e-72 278.5 Verrucomicrobiae pgdA GO:0005575,GO:0016020 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 2IU6W@203494,46UKH@74201,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase JOKFNDED_01329 382464.ABSI01000006_gene793 6.8e-208 730.3 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_01330 857087.Metme_3504 5.9e-116 424.9 Proteobacteria phoX ko:K07093 ko00000 Bacteria 1R690@1224,COG3211@1,COG3211@2 NA|NA|NA S Bacterial protein of unknown function (DUF839) JOKFNDED_01331 1403819.BATR01000092_gene2714 1.1e-92 347.8 Verrucomicrobiae Bacteria 2IUBJ@203494,46TUY@74201,COG2304@1,COG2304@2 NA|NA|NA S Aerotolerance regulator N-terminal JOKFNDED_01332 240016.ABIZ01000001_gene1386 1.1e-155 558.1 Verrucomicrobiae Bacteria 2IU3J@203494,46TD8@74201,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation JOKFNDED_01333 240016.ABIZ01000001_gene1387 2.4e-166 592.8 Verrucomicrobiae Bacteria 2ITXR@203494,46UE9@74201,COG5426@1,COG5426@2 NA|NA|NA S von Willebrand factor, type A JOKFNDED_01334 886293.Sinac_0400 2.5e-66 259.2 Planctomycetes 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 2IZ2A@203682,COG4249@1,COG4249@2 NA|NA|NA S Peptidase C14 caspase catalytic subunit p20 JOKFNDED_01335 1121405.dsmv_3021 1.2e-52 214.2 Proteobacteria Bacteria 1NVKS@1224,2CGZ8@1,31WRF@2 NA|NA|NA JOKFNDED_01336 1236541.BALL01000027_gene3118 1e-107 397.1 Gammaproteobacteria GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 Bacteria 1MXTM@1224,1RNYZ@1236,COG4325@1,COG4325@2 NA|NA|NA S Membrane JOKFNDED_01337 1403819.BATR01000150_gene5084 5.6e-27 126.7 Verrucomicrobiae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4715 Bacteria 2IU4R@203494,46SNB@74201,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) JOKFNDED_01338 497964.CfE428DRAFT_0129 3.3e-78 298.1 Verrucomicrobia pdhB 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2753 Bacteria 46S75@74201,COG0022@1,COG0022@2 NA|NA|NA C PFAM Transketolase central region JOKFNDED_01339 497964.CfE428DRAFT_0130 7.2e-114 417.5 Verrucomicrobia pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 46SHZ@74201,COG0508@1,COG0508@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) JOKFNDED_01340 497964.CfE428DRAFT_0127 7.6e-173 613.6 Verrucomicrobia lpdA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 46S7E@74201,COG1249@1,COG1249@2 NA|NA|NA C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase JOKFNDED_01341 1545915.JROG01000001_gene588 9.8e-71 276.6 Sphingomonadales yapH ko:K13735,ko:K19231 ko05100,map05100 ko00000,ko00001,ko02000 1.B.12 Bacteria 1MU92@1224,2K2RZ@204457,2TSB7@28211,COG2911@1,COG2911@2,COG3210@1,COG3210@2,COG3468@1,COG3468@2,COG4625@1,COG4625@2 NA|NA|NA U protein with a C-terminal OMP (outer membrane protein) domain JOKFNDED_01342 382464.ABSI01000020_gene219 0.0 1279.2 Bacteria Bacteria COG1002@1,COG1002@2 NA|NA|NA V DNA modification JOKFNDED_01344 234267.Acid_5331 1e-160 573.9 Bacteria Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity JOKFNDED_01345 1403819.BATR01000055_gene1737 1.8e-09 68.2 Verrucomicrobia Bacteria 298X9@1,2ZW14@2,46WTG@74201 NA|NA|NA JOKFNDED_01346 762903.Pedsa_1075 2.4e-34 151.8 Sphingobacteriia lcdH 1.1.1.108 ko:K07107,ko:K12500,ko:K17735 ko00000,ko01000,ko01004 Bacteria 1ISVV@117747,4NR6U@976,COG0824@1,COG0824@2 NA|NA|NA S thioesterase JOKFNDED_01348 240016.ABIZ01000001_gene3487 2.2e-72 279.3 Verrucomicrobiae 2.7.13.3 ko:K11617 ko02020,map02020 M00481,M00754 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IV76@203494,46SBM@74201,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase JOKFNDED_01349 1396418.BATQ01000082_gene1183 2.7e-66 258.5 Bacteria ko:K02479 ko00000,ko02022 Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator JOKFNDED_01350 657309.BXY_18880 4.2e-22 112.1 Bacteroidaceae 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2FMZ8@200643,4ANPZ@815,4NGNU@976,COG0584@1,COG0584@2 NA|NA|NA C COG0584 Glycerophosphoryl diester phosphodiesterase JOKFNDED_01353 391612.CY0110_03059 1.4e-13 82.4 Cyanothece Bacteria 1G851@1117,3KK65@43988,COG2886@1,COG2886@2 NA|NA|NA S Uncharacterised protein family (UPF0175) JOKFNDED_01354 1266914.ATUK01000011_gene2387 7.3e-16 89.7 Chromatiales Bacteria 1MZK1@1224,1S9TU@1236,1X1AC@135613,2D2Z4@1,32TDX@2 NA|NA|NA S Protein of unknown function (DUF3024) JOKFNDED_01355 1403819.BATR01000146_gene4992 0.0 1432.5 Verrucomicrobiae Bacteria 2IVNC@203494,46TF1@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_01356 240016.ABIZ01000001_gene2927 4.4e-163 580.9 Verrucomicrobiae Bacteria 2IWP4@203494,46UHD@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_01359 313628.LNTAR_09801 7.8e-114 417.5 Bacteria 3.1.6.12 ko:K01135,ko:K01138 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_01360 583355.Caka_1478 3.8e-308 1063.5 Opitutae nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 3K76K@414999,46SFJ@74201,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides JOKFNDED_01361 1396141.BATP01000056_gene3301 9.7e-21 107.5 Verrucomicrobiae Bacteria 2IWGR@203494,46XSD@74201,COG2885@1,COG2885@2 NA|NA|NA M OmpA family JOKFNDED_01362 1429916.X566_15870 4.3e-33 149.4 Alphaproteobacteria Bacteria 1RBEA@1224,2U6AK@28211,COG2319@1,COG2319@2 NA|NA|NA C Domain of unknown function (DUF4384) JOKFNDED_01363 56780.SYN_02036 1.1e-172 613.6 Syntrophobacterales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1MW8K@1224,2MQ7A@213462,2WKQW@28221,42NNC@68525,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A JOKFNDED_01364 1403819.BATR01000104_gene3521 3.9e-65 255.8 Bacteria Bacteria 2DK2X@1,3089T@2 NA|NA|NA JOKFNDED_01365 1396418.BATQ01000184_gene2605 2e-106 393.3 Verrucomicrobiae 3.1.1.53 ko:K05970 ko00000,ko01000 Bacteria 2IWKD@203494,46U1X@74201,COG2755@1,COG2755@2 NA|NA|NA E Carbohydrate esterase, sialic acid-specific acetylesterase JOKFNDED_01367 1123508.JH636443_gene4921 9.4e-273 946.8 Bacteria ko:K08676 ko00000,ko01000,ko01002 Bacteria COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M serine-type peptidase activity JOKFNDED_01369 1500259.JQLD01000002_gene3008 7.5e-48 198.7 Alphaproteobacteria 2.1.1.80,3.1.1.61 ko:K03406,ko:K13924,ko:K21449 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.B.40.2 Bacteria 1QUXB@1224,2TWTY@28211,COG2202@1,COG2202@2,COG2982@1,COG2982@2,COG3209@1,COG3209@2,COG3210@1,COG3210@2,COG5295@1,COG5295@2 NA|NA|NA U PFAM SMP-30 Gluconolaconase JOKFNDED_01370 1396141.BATP01000006_gene5443 1.6e-28 132.9 Verrucomicrobiae Bacteria 2IVH1@203494,46UX1@74201,COG2133@1,COG2133@2 NA|NA|NA G Cytochrome c JOKFNDED_01371 1337936.IJ00_18080 1.4e-10 74.3 Nostocales ko:K03286,ko:K16191 ko00000,ko02000 1.B.6,1.B.6.1.3 Bacteria 1G1SI@1117,1HQTB@1161,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family JOKFNDED_01374 1120948.KB903248_gene4346 2.5e-11 73.9 Pseudonocardiales Bacteria 2GM57@201174,4E4HQ@85010,COG2340@1,COG2340@2 NA|NA|NA S protein with SCP PR1 domains JOKFNDED_01375 743721.Psesu_0502 3e-39 168.7 Xanthomonadales pgsAb 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 1RHFC@1224,1S6C6@1236,1X84A@135614,COG0558@1,COG0558@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase JOKFNDED_01376 1396418.BATQ01000131_gene3968 1.5e-45 189.5 Verrucomicrobia plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 46WIM@74201,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases JOKFNDED_01377 631362.Thi970DRAFT_04636 1e-107 396.7 Chromatiales cdsA 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX58@1224,1RRAG@1236,1WY6I@135613,COG4589@1,COG4589@2 NA|NA|NA I Cytidylyltransferase family JOKFNDED_01378 240016.ABIZ01000001_gene2172 1.3e-113 416.4 Verrucomicrobiae Bacteria 28H6T@1,2IU2J@203494,2Z7J4@2,46UZY@74201 NA|NA|NA JOKFNDED_01379 243090.RB2897 1.4e-51 209.5 Planctomycetes Bacteria 2IZWV@203682,COG3963@1,COG3963@2 NA|NA|NA I Methyltransferase domain JOKFNDED_01380 1151122.AQYD01000005_gene2992 7.1e-24 117.1 Microbacteriaceae Bacteria 28XTZ@1,2H90A@201174,32464@2,4FSPR@85023 NA|NA|NA JOKFNDED_01381 344747.PM8797T_23049 3.2e-14 86.3 Bacteria Bacteria 2CBIH@1,33WXG@2 NA|NA|NA JOKFNDED_01382 926549.KI421517_gene3391 5e-127 461.1 Cytophagia yrbE Bacteria 47NZU@768503,4NG5E@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_01383 1396141.BATP01000016_gene2814 1.1e-207 729.6 Verrucomicrobiae CP_0904 Bacteria 2ITKZ@203494,46S61@74201,COG1055@1,COG1055@2 NA|NA|NA P Putative Na+/H+ antiporter JOKFNDED_01384 1396141.BATP01000022_gene456 1.1e-228 799.7 Verrucomicrobiae recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITT4@203494,46U82@74201,COG0514@1,COG0514@2 NA|NA|NA L RQC JOKFNDED_01385 1380390.JIAT01000013_gene287 1.5e-12 80.9 Bacteria Bacteria COG5653@1,COG5653@2 NA|NA|NA M Protein involved in cellulose biosynthesis JOKFNDED_01386 344747.PM8797T_03119 3.8e-72 278.1 Planctomycetes Bacteria 28NEV@1,2J273@203682,33RXV@2 NA|NA|NA JOKFNDED_01387 1121930.AQXG01000005_gene635 3.2e-55 221.5 Sphingobacteriia btuE 1.11.1.22,1.11.1.9 ko:K00432,ko:K20207 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 iJN678.slr1992 Bacteria 1IS94@117747,4NM6G@976,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family JOKFNDED_01388 700598.Niako_6699 1.3e-77 296.6 Sphingobacteriia Bacteria 1IQBS@117747,4NH6Y@976,COG1028@1,COG1028@2 NA|NA|NA IQ short-chain dehydrogenase JOKFNDED_01390 1396141.BATP01000005_gene6057 9.9e-254 883.2 Verrucomicrobiae ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2ITGB@203494,46TXD@74201,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A domain JOKFNDED_01391 595460.RRSWK_02368 2.9e-54 219.2 Planctomycetes ko:K09992 ko00000 Bacteria 2IXPS@203682,COG3828@1,COG3828@2 NA|NA|NA S Trehalose utilisation JOKFNDED_01392 1403819.BATR01000103_gene3466 5e-78 298.1 Verrucomicrobia Bacteria 46TUG@74201,COG1801@1,COG1801@2 NA|NA|NA S Protein of unknown function DUF72 JOKFNDED_01393 1403819.BATR01000163_gene5500 1.1e-201 709.9 Verrucomicrobiae nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU20@203494,46TGA@74201,COG0363@1,COG0363@2,COG2120@1,COG2120@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion JOKFNDED_01394 1255043.TVNIR_1335 2.1e-16 91.3 Bacteria CP_0257 ko:K09131 ko00000 Bacteria COG1872@1,COG1872@2 NA|NA|NA I DUF167 JOKFNDED_01395 314230.DSM3645_07151 7.7e-78 297.7 Planctomycetes Bacteria 2CCRZ@1,2IWWX@203682,2Z7J6@2 NA|NA|NA JOKFNDED_01396 517418.Ctha_1616 4.6e-103 381.3 Chlorobi ccpA 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria 1FDVA@1090,COG1858@1,COG1858@2 NA|NA|NA C PFAM Di-haem cytochrome c peroxidase JOKFNDED_01397 240016.ABIZ01000001_gene3059 3.7e-24 119.4 Verrucomicrobiae bamD ko:K05807,ko:K07114,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.A.13.2.2,1.A.13.2.3,1.B.33.1 GH23 Bacteria 2IUQE@203494,46SYU@74201,COG1729@1,COG1729@2,COG4105@1,COG4105@2 NA|NA|NA S Outer membrane lipoprotein JOKFNDED_01398 240016.ABIZ01000001_gene3060 7.8e-21 107.5 Verrucomicrobiae Bacteria 2EM72@1,2IUQI@203494,33EW9@2,46TAB@74201 NA|NA|NA S Lipopolysaccharide-assembly JOKFNDED_01399 1396141.BATP01000006_gene5450 5.1e-67 261.2 Verrucomicrobiae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2IU7K@203494,46SVC@74201,COG0313@1,COG0313@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases JOKFNDED_01401 1123070.KB899251_gene725 3e-70 271.9 Verrucomicrobiae panB GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.11,6.3.2.1 ko:K00606,ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R01226,R02473 RC00022,RC00096,RC00141,RC00200 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00132,iE2348C_1286.E2348C_0137,iECBD_1354.ECBD_3485,iECB_1328.ECB_00133,iECD_1391.ECD_00133,iPC815.YPO3401,iYO844.BSU22430 Bacteria 2IU4C@203494,46SPN@74201,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate JOKFNDED_01402 1396141.BATP01000003_gene5176 5.8e-133 481.5 Verrucomicrobiae rho ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2ITRJ@203494,46UQY@74201,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template JOKFNDED_01403 1121403.AUCV01000059_gene3338 1.4e-79 303.5 Deltaproteobacteria Bacteria 1NG06@1224,2WUIC@28221,42RH3@68525,COG0628@1,COG0628@2 NA|NA|NA S Transmembrane protein 43 JOKFNDED_01404 643473.KB235930_gene4319 8.4e-25 120.6 Nostocales Bacteria 1G6SI@1117,1HN9M@1161,2DMJE@1,32RYR@2 NA|NA|NA S Domain of unknown function (DUF4112) JOKFNDED_01405 1396418.BATQ01000091_gene5801 6.3e-53 214.9 Verrucomicrobiae lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 Bacteria 2IUBP@203494,46STR@74201,COG0795@1,COG0795@2 NA|NA|NA S Predicted permease YjgP/YjgQ family JOKFNDED_01407 640081.Dsui_2799 7.6e-30 137.5 Rhodocyclales gsiA ko:K02031,ko:K02032,ko:K12371,ko:K13892 ko02010,ko02024,map02010,map02024 M00239,M00324,M00348 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 Bacteria 1MU09@1224,2KVAJ@206389,2VH5T@28216,COG1123@1,COG4172@2 NA|NA|NA P Belongs to the ABC transporter superfamily JOKFNDED_01408 240016.ABIZ01000001_gene4317 5.3e-95 354.8 Verrucomicrobiae rodA ko:K05837 ko00000,ko03036 Bacteria 2IU76@203494,46SQT@74201,COG0772@1,COG0772@2 NA|NA|NA D Cell cycle protein JOKFNDED_01409 1120959.ATXF01000007_gene2331 1e-178 632.9 Microbacteriaceae Bacteria 2HSAV@201174,4FMKU@85023,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain JOKFNDED_01411 344747.PM8797T_17619 1.4e-63 249.6 Bacteria Bacteria COG3828@1,COG3828@2 NA|NA|NA N Trehalose utilisation JOKFNDED_01412 1396418.BATQ01000149_gene2223 1.4e-48 199.1 Verrucomicrobiae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2IUAH@203494,46VGJ@74201,COG0691@1,COG0691@2 NA|NA|NA O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA JOKFNDED_01413 1396141.BATP01000003_gene4995 9.5e-147 526.6 Verrucomicrobiae aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iIT341.HP0663,iJN678.aroC Bacteria 2ITMN@203494,46SEA@74201,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system JOKFNDED_01415 1396418.BATQ01000001_gene1313 3e-180 638.3 Verrucomicrobiae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2ITJA@203494,46S5X@74201,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) JOKFNDED_01416 1396141.BATP01000035_gene4040 3.5e-31 141.7 Verrucomicrobiae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601,ko:K05785 ko00000,ko03000,ko03009,ko03021 Bacteria 2IV04@203494,46ZE1@74201,COG0250@1,COG0250@2 NA|NA|NA K Transcription termination factor nusG JOKFNDED_01417 234267.Acid_2753 2.3e-18 98.6 Acidobacteria Bacteria 3Y8TA@57723,COG3744@1,COG3744@2 NA|NA|NA S PIN domain JOKFNDED_01418 300852.55771870 7.1e-08 63.2 Deinococcus-Thermus Bacteria 1WKUP@1297,COG4118@1,COG4118@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module JOKFNDED_01419 1396418.BATQ01000020_gene5042 4.3e-98 364.8 Verrucomicrobia Bacteria 28IED@1,2Z8GE@2,46VP7@74201 NA|NA|NA S Protein of unknown function (DUF3500) JOKFNDED_01420 511062.GU3_05630 3e-07 61.6 Gammaproteobacteria ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 Bacteria 1N5P8@1224,1S9K3@1236,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_01422 75379.Tint_1238 8.7e-14 84.3 Betaproteobacteria ko:K02282 ko00000,ko02035,ko02044 Bacteria 1MWGM@1224,2VME6@28216,COG2197@1,COG2197@2 NA|NA|NA K response regulator JOKFNDED_01423 349741.Amuc_0362 1.3e-11 76.3 Verrucomicrobiae Bacteria 2ERYI@1,2IUEZ@203494,33JHP@2,46WPE@74201 NA|NA|NA JOKFNDED_01426 452637.Oter_3861 1.5e-167 596.7 Opitutae mdoH GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 ko:K03669 ko00000,ko01000,ko01003,ko02000 4.D.3.1.1 GT2 Bacteria 3K7AG@414999,46S7P@74201,COG2943@1,COG2943@2 NA|NA|NA M Glycosyl transferase family 21 JOKFNDED_01427 497964.CfE428DRAFT_6435 1.4e-26 127.1 Verrucomicrobia Bacteria 2DMZE@1,32UJW@2,46T2C@74201 NA|NA|NA JOKFNDED_01429 765912.Thimo_3195 2.1e-42 179.5 Proteobacteria ko:K07025 ko00000 Bacteria 1RJAJ@1224,COG1011@1,COG1011@2 NA|NA|NA S HAD-hyrolase-like JOKFNDED_01430 1121403.AUCV01000008_gene1543 8.7e-95 354.4 Deltaproteobacteria 2.4.1.270 ko:K21369 ko00000,ko01000,ko01003 GT4 Bacteria 1R2HF@1224,2X8JT@28221,43DDY@68525,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_01431 1379281.AVAG01000032_gene115 2.8e-137 495.0 Bacteria gpgS 2.4.1.266,2.4.1.268 ko:K13693,ko:K21349 ko00000,ko01000,ko01003 GT81 Bacteria COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_01432 583355.Caka_1158 4.8e-80 305.1 Bacteria Bacteria COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase activity JOKFNDED_01433 240016.ABIZ01000001_gene4539 3e-198 698.0 Verrucomicrobiae rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 2ITS9@203494,46S5U@74201,COG0621@1,COG0621@2 NA|NA|NA J Uncharacterized protein family UPF0004 JOKFNDED_01434 1206777.B195_01720 7.1e-116 424.9 Pseudomonas syringae group Bacteria 1MV2W@1224,1RQS2@1236,1Z6HK@136849,COG1835@1,COG1835@2 NA|NA|NA M Acyltransferase family JOKFNDED_01435 1123070.KB899258_gene1949 4.7e-166 590.9 Verrucomicrobiae fabF_1 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2ITS2@203494,46SBU@74201,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP JOKFNDED_01437 1403819.BATR01000053_gene1621 2.5e-07 62.8 Verrucomicrobia Bacteria 298B0@1,2ZVGI@2,46WFY@74201 NA|NA|NA JOKFNDED_01438 1396418.BATQ01000176_gene2688 4.3e-11 74.3 Verrucomicrobiae ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUX5@203494,46T9R@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_01439 240016.ABIZ01000001_gene5311 2.5e-60 238.8 Verrucomicrobiae exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUER@203494,46SUA@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_01442 1123060.JONP01000001_gene1556 1.5e-73 283.9 Rhodospirillales parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1MVH1@1224,2JPPI@204441,2TQZV@28211,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule JOKFNDED_01443 497964.CfE428DRAFT_6520 1.6e-31 143.3 Verrucomicrobia ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 46T1R@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_01444 1403819.BATR01000031_gene1011 9.5e-23 113.2 Verrucomicrobiae ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUR9@203494,46T7H@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_01445 1396141.BATP01000024_gene808 1e-56 226.5 Verrucomicrobiae def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2IUCF@203494,46SYF@74201,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions JOKFNDED_01454 1403819.BATR01000167_gene5708 4.4e-73 281.6 Bacteria 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria COG2378@1,COG2378@2 NA|NA|NA K regulation of single-species biofilm formation JOKFNDED_01456 313596.RB2501_01520 7.7e-61 241.1 Flavobacteriia Bacteria 1I800@117743,4NIDT@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_01457 756272.Plabr_0630 9.5e-193 679.9 Planctomycetes Bacteria 2IXR4@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_01458 497964.CfE428DRAFT_2104 5.6e-27 127.9 Verrucomicrobia 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 46W7N@74201,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues JOKFNDED_01459 1123242.JH636434_gene4856 1.9e-166 592.4 Planctomycetes ko:K03307 ko00000 2.A.21 Bacteria 2J2KC@203682,COG0591@1,COG0591@2 NA|NA|NA E Sodium:solute symporter family JOKFNDED_01462 1396418.BATQ01000179_gene3159 3.5e-67 261.5 Bacteria Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator JOKFNDED_01463 240016.ABIZ01000001_gene5349 3.7e-222 778.5 Verrucomicrobiae pslD ko:K01991,ko:K03615,ko:K09690,ko:K20987 ko02010,ko02025,ko02026,map02010,map02025,map02026 M00250 ko00000,ko00001,ko00002,ko02000 1.B.18,3.A.1.103 Bacteria 2IUWB@203494,46ZHY@74201,COG1596@1,COG1596@2,COG3206@1,COG3206@2 NA|NA|NA M Polysaccharide biosynthesis/export protein JOKFNDED_01464 240016.ABIZ01000001_gene5351 3.8e-117 428.3 Verrucomicrobiae Bacteria 2IVB9@203494,46VHB@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_01465 240016.ABIZ01000001_gene5352 1.6e-224 785.8 Verrucomicrobiae 2.4.1.187 ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 GT26 Bacteria 2IUM7@203494,46VQJ@74201,COG0438@1,COG0438@2,COG1922@1,COG1922@2 NA|NA|NA M Glycosyl transferase WecB/TagA/CpsF family JOKFNDED_01466 240016.ABIZ01000001_gene5354 1.8e-65 256.5 Verrucomicrobiae Bacteria 2CCWM@1,2IVHM@203494,338WR@2,46ZKG@74201 NA|NA|NA JOKFNDED_01467 240016.ABIZ01000001_gene5355 1.3e-134 486.5 Verrucomicrobiae Bacteria 2IV4I@203494,46X9P@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_01468 240016.ABIZ01000001_gene5357 8.3e-93 347.1 Verrucomicrobiae ko:K12992 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 GT2 Bacteria 2IVPA@203494,46XEI@74201,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 JOKFNDED_01469 240016.ABIZ01000001_gene5358 1e-141 510.4 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process JOKFNDED_01470 240016.ABIZ01000001_gene5359 8e-129 467.2 Verrucomicrobiae gumH 2.4.1.252 ko:K13657 R09733 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 2IV7H@203494,46ZJA@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_01471 1129794.C427_4367 1.5e-55 222.6 Gammaproteobacteria Bacteria 1N4ZG@1224,1SR1B@1236,COG1060@1,COG1060@2 NA|NA|NA H Haem-NO-binding JOKFNDED_01473 1396141.BATP01000028_gene2351 1.2e-120 439.9 Verrucomicrobiae avtA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.66 ko:K00835 ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130 R01215 RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 iEKO11_1354.EKO11_0154,iEcSMS35_1347.EcSMS35_3895 Bacteria 2ITU5@203494,46YY9@74201,COG3977@1,COG3977@2 NA|NA|NA E Aminotransferase class I and II JOKFNDED_01475 497964.CfE428DRAFT_3893 7.5e-48 196.8 Verrucomicrobia coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 46SUT@74201,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate JOKFNDED_01479 497964.CfE428DRAFT_0637 5.8e-30 137.5 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_01480 1210884.HG799470_gene14529 2.1e-258 899.0 Planctomycetes Bacteria 2IY0D@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_01481 240016.ABIZ01000001_gene5027 1.2e-10 73.6 Verrucomicrobiae Bacteria 2AX3V@1,2IWE0@203494,31P28@2,46XQV@74201 NA|NA|NA JOKFNDED_01482 1379270.AUXF01000001_gene1900 1.4e-164 586.3 Gemmatimonadetes 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1ZT3U@142182,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase alpha chain JOKFNDED_01483 411901.BACCAC_00075 2.1e-88 333.6 Bacteria 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria COG1874@1,COG1874@2 NA|NA|NA G beta-galactosidase activity JOKFNDED_01484 756272.Plabr_3146 1.2e-221 776.2 Planctomycetes Bacteria 2IYV9@203682,COG5492@1,COG5492@2 NA|NA|NA N Domain of unknown function (DUF5060) JOKFNDED_01485 1403819.BATR01000027_gene887 6.7e-311 1073.2 Bacteria Bacteria 2DU8X@1,33PEA@2 NA|NA|NA JOKFNDED_01486 1396141.BATP01000047_gene3929 8.1e-187 659.8 Verrucomicrobiae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 2IV69@203494,46XA8@74201,COG3345@1,COG3345@2 NA|NA|NA G Carbohydrate esterase, sialic acid-specific acetylesterase JOKFNDED_01487 595460.RRSWK_06781 1e-196 693.0 Planctomycetes Bacteria 2IYMC@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_01488 530564.Psta_1293 6.7e-223 780.0 Planctomycetes Bacteria 2IY4T@203682,COG3119@1,COG3119@2 NA|NA|NA P Domain of unknown function JOKFNDED_01489 748247.AZKH_0325 4.6e-07 62.8 Betaproteobacteria ko:K07126 ko00000 Bacteria 1MWPA@1224,2VM3A@28216,COG0790@1,COG0790@2 NA|NA|NA KLT PFAM Sel1 domain protein repeat-containing protein JOKFNDED_01490 589865.DaAHT2_0326 1.8e-92 345.9 Proteobacteria ko:K09144 ko00000 Bacteria 1PNER@1224,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system JOKFNDED_01491 589865.DaAHT2_0325 5.7e-52 210.7 Proteobacteria Bacteria 1RAHV@1224,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score JOKFNDED_01492 1396141.BATP01000059_gene2529 1.5e-56 226.9 Bacteria Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process JOKFNDED_01493 1415780.JPOG01000001_gene2654 1.4e-50 207.2 Xanthomonadales Bacteria 1MV6Z@1224,1RNIU@1236,1X6EG@135614,COG2370@1,COG2370@2 NA|NA|NA O HupE / UreJ protein JOKFNDED_01495 349741.Amuc_0629 1.5e-133 482.6 Verrucomicrobiae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITRW@203494,46SDS@74201,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing JOKFNDED_01497 530564.Psta_0824 3.3e-85 322.0 Planctomycetes 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2J1YU@203682,COG3540@1,COG3540@2 NA|NA|NA P PhoD-like phosphatase JOKFNDED_01499 765420.OSCT_1945 1.3e-57 229.6 Chloroflexia Bacteria 2GAHS@200795,3767J@32061,COG0330@1,COG0330@2 NA|NA|NA O PFAM band 7 protein JOKFNDED_01500 1123070.KB899247_gene1634 1.2e-205 723.0 Verrucomicrobiae htpG GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701 ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Bacteria 2IU3I@203494,46U76@74201,COG0326@1,COG0326@2 NA|NA|NA O Hsp90 protein JOKFNDED_01502 1519464.HY22_11920 4.1e-65 255.8 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_01503 240016.ABIZ01000001_gene1248 5.4e-189 667.9 Verrucomicrobiae ko:K16087 ko00000,ko02000 1.B.14.2 Bacteria 2IU2X@203494,46Z2R@74201,COG4206@1,COG4206@2 NA|NA|NA H TonB dependent receptor JOKFNDED_01504 240016.ABIZ01000001_gene1250 3.5e-71 275.8 Verrucomicrobia ko:K02481,ko:K07712 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko02022 Bacteria 46U7R@74201,COG2204@1,COG2204@2 NA|NA|NA T Sigma-54 interaction domain JOKFNDED_01505 1403819.BATR01000184_gene6360 4.6e-13 80.5 Verrucomicrobia 2.7.13.3 ko:K15011 ko02020,map02020 M00523 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 46U8F@74201,COG4191@1,COG4191@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain JOKFNDED_01508 1123070.KB899267_gene2467 5.4e-21 108.6 Bacteria pslD ko:K01991,ko:K20987 ko02025,ko02026,map02025,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria COG1596@1,COG1596@2 NA|NA|NA M polysaccharide export JOKFNDED_01509 1396141.BATP01000056_gene3235 7.9e-67 261.9 Verrucomicrobiae ko:K16692 ko00000,ko01000,ko01001 Bacteria 2IUKC@203494,46V4D@74201,COG0489@1,COG0489@2 NA|NA|NA D PFAM lipopolysaccharide biosynthesis protein JOKFNDED_01511 1269813.ATUL01000024_gene698 8.5e-79 301.2 Chromatiales ko:K04763 ko00000,ko03036 Bacteria 1MVAN@1224,1RMSS@1236,1WWPX@135613,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family JOKFNDED_01513 1403819.BATR01000029_gene945 6.7e-19 101.3 Bacteria Bacteria 2C0JI@1,33E1V@2 NA|NA|NA S Protein of unknown function (DUF4013) JOKFNDED_01516 1396418.BATQ01000056_gene240 1.4e-162 580.1 Verrucomicrobiae 2.1.1.80,2.7.13.3,3.1.1.61 ko:K02030,ko:K03407,ko:K07679,ko:K13924 ko02020,ko02030,ko05133,map02020,map02030,map05133 M00236,M00477,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035 3.A.1.3 Bacteria 2IWNI@203494,46UM4@74201,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T CHASE3 domain JOKFNDED_01517 1396418.BATQ01000056_gene239 6.1e-117 427.6 Verrucomicrobiae M1-573 2.7.13.3 ko:K11527 ko00000,ko01000,ko01001,ko02022 Bacteria 2IV4P@203494,46UCX@74201,COG0642@1,COG2199@1,COG2205@2,COG3706@2 NA|NA|NA T PhoQ Sensor JOKFNDED_01519 497964.CfE428DRAFT_0074 2.7e-38 166.0 Verrucomicrobia Bacteria 2EV5U@1,33NKM@2,46WDA@74201 NA|NA|NA JOKFNDED_01520 1121106.JQKB01000059_gene4762 3.8e-15 88.2 Proteobacteria Bacteria 1NRP8@1224,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_01523 497964.CfE428DRAFT_1541 7.8e-44 183.7 Verrucomicrobia ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 46VGA@74201,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism JOKFNDED_01524 102232.GLO73106DRAFT_00027280 1.6e-138 499.2 Cyanobacteria Bacteria 1G3UX@1117,COG1363@1,COG1363@2 NA|NA|NA G M42 glutamyl aminopeptidase JOKFNDED_01525 1403819.BATR01000164_gene5531 3.4e-31 142.5 Verrucomicrobiae Bacteria 2ITT7@203494,46TWC@74201,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2 NA|NA|NA CEG Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_01526 1131462.DCF50_p48 6e-115 421.8 Peptococcaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,247RM@186801,260F2@186807,COG0210@1,COG0210@2 NA|NA|NA L PFAM UvrD REP helicase JOKFNDED_01527 864073.HFRIS_001220 3.9e-105 389.0 Oxalobacteraceae ybjD GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K07459 ko00000 Bacteria 1N2CB@1224,2WENX@28216,478WK@75682,COG1106@1,COG1106@2,COG3593@1,COG3593@2 NA|NA|NA L AAA ATPase domain JOKFNDED_01528 1210884.HG799475_gene15241 1e-145 524.6 Planctomycetes Bacteria 2IXWZ@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Dehydrogenase JOKFNDED_01529 537011.PREVCOP_04970 3.5e-44 184.9 Bacteroidia Bacteria 2AQK9@1,2FWGH@200643,31FT7@2,4NMIG@976 NA|NA|NA JOKFNDED_01531 1403819.BATR01000051_gene1487 7.6e-169 600.5 Verrucomicrobiae serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITN1@203494,46Z6K@74201,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain JOKFNDED_01532 452637.Oter_4097 2.3e-85 322.4 Opitutae yocS ko:K03453,ko:K14347 ko00000,ko02000,ko04147 2.A.28,2.A.93.1 Bacteria 3K9UA@414999,46YMH@74201,COG0385@1,COG0385@2 NA|NA|NA S Bile acid sodium symporter JOKFNDED_01533 349741.Amuc_0166 5.2e-134 484.2 Verrucomicrobiae pilT ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2ITP5@203494,46SY2@74201,COG2805@1,COG2805@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_01535 314230.DSM3645_08020 1.4e-51 209.9 Planctomycetes Bacteria 28IP5@1,2IX86@203682,2Z8P7@2 NA|NA|NA S Methane oxygenase PmoA JOKFNDED_01536 1396141.BATP01000002_gene4834 6.5e-140 503.8 Verrucomicrobiae Bacteria 2IVJQ@203494,46ZKQ@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_01537 1123242.JH636434_gene3936 5.6e-09 68.2 Planctomycetes ko:K06142 ko00000 Bacteria 2J441@203682,COG2825@1,COG2825@2 NA|NA|NA M Outer membrane protein (OmpH-like) JOKFNDED_01538 595460.RRSWK_01975 0.0 1133.2 Bacteria wcbR Bacteria COG3321@1,COG3321@2 NA|NA|NA Q synthase JOKFNDED_01539 1121013.P873_00385 1.3e-128 466.5 Proteobacteria Bacteria 1RCHW@1224,COG0464@1,COG0464@2 NA|NA|NA O ATPase family associated with various cellular activities (AAA) JOKFNDED_01540 497964.CfE428DRAFT_2154 3e-210 738.8 Verrucomicrobia ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 46SCV@74201,COG1674@1,COG1674@2 NA|NA|NA D PFAM cell divisionFtsK SpoIIIE JOKFNDED_01541 1104325.M7W_2605 4.8e-07 62.4 Enterococcaceae ymfM ko:K15539 ko00000 Bacteria 1V1N7@1239,4B68M@81852,4HKW3@91061,COG1426@1,COG1426@2 NA|NA|NA S Domain of unknown function (DUF4115) JOKFNDED_01544 530564.Psta_0745 2.6e-167 595.1 Planctomycetes Bacteria 2IYMG@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_01545 1341155.FSS13T_10010 9.7e-80 305.8 Flavobacterium Bacteria 1I33Y@117743,2P0DI@237,4NM9F@976,COG3386@1,COG3386@2 NA|NA|NA GN Domain of unknown function (DUF5122) beta-propeller JOKFNDED_01546 373903.Hore_01870 4.4e-29 135.2 Clostridia lgt_2 ko:K13292 ko00000,ko01000 Bacteria 1TPAK@1239,24BK7@186801,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins JOKFNDED_01547 452637.Oter_1686 1.2e-51 209.9 Opitutae hly3 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K11068 ko00000,ko02042 Bacteria 3K7KU@414999,46T25@74201,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related JOKFNDED_01549 1403819.BATR01000096_gene3162 4.8e-104 384.4 Verrucomicrobiae argF 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU2R@203494,46SA5@74201,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline JOKFNDED_01550 1396141.BATP01000030_gene3552 3e-33 148.3 Verrucomicrobiae argD 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2ITW4@203494,46SUV@74201,COG4992@1,COG4992@2 NA|NA|NA E Aminotransferase class-III JOKFNDED_01551 880072.Desac_0075 2.1e-47 195.3 Syntrophobacterales 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,2MR4B@213462,2X2AD@28221,42M3B@68525,COG0286@1,COG0286@2,COG0732@1,COG0732@2 NA|NA|NA L HsdM N-terminal domain JOKFNDED_01552 340177.Cag_1884 3.7e-66 258.1 Bacteria Bacteria 2C3YW@1,2ZBK3@2 NA|NA|NA S Domain of unknown function (DUF4062) JOKFNDED_01553 340177.Cag_1885 5.7e-139 501.1 Chlorobi 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1FFG1@1090,COG2865@1,COG2865@2,COG3177@1,COG3177@2 NA|NA|NA K PFAM AAA-4 family protein JOKFNDED_01554 1177154.Y5S_01818 1e-90 340.5 Gammaproteobacteria 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 ko00000,ko01000,ko02048 Bacteria 1R5R8@1224,1S9TA@1236,COG0732@1,COG0732@2 NA|NA|NA V COG0732 Restriction endonuclease S subunits JOKFNDED_01556 439235.Dalk_0695 3.4e-77 295.0 Proteobacteria Bacteria 1NX37@1224,28JYH@1,2Z9NS@2 NA|NA|NA JOKFNDED_01557 439235.Dalk_0696 0.0 1318.5 Desulfobacterales Bacteria 1MW4Z@1224,2MPB3@213118,2WQUX@28221,42TK8@68525,COG1204@1,COG1204@2 NA|NA|NA L DEAD DEAH box helicase domain protein JOKFNDED_01558 644282.Deba_2537 0.0 1407.1 Deltaproteobacteria hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1MU96@1224,2WIT1@28221,42M86@68525,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification JOKFNDED_01559 1123401.JHYQ01000026_gene3289 8.5e-48 197.2 Gammaproteobacteria ko:K08984 ko00000 Bacteria 1N7NB@1224,1S3J8@1236,COG3647@1,COG3647@2 NA|NA|NA S Predicted membrane protein (DUF2238) JOKFNDED_01560 1396418.BATQ01000058_gene99 1.6e-68 267.3 Verrucomicrobiae 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 2IVQ0@203494,46UX2@74201,COG5164@1,COG5164@2 NA|NA|NA K regulation of DNA-templated transcription, elongation JOKFNDED_01564 1396141.BATP01000027_gene1129 1.4e-48 200.7 Bacteria Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity JOKFNDED_01565 7165.AGAP012078-PA 1.3e-69 270.4 Nematocera GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02835 ko00000,ko03012 Arthropoda 38CVW@33154,3B9G3@33208,3CTVN@33213,3SI29@50557,41XR4@6656,44Y4V@7147,45FD8@7148,COG0216@1,KOG2726@2759 NA|NA|NA J peptide chain release factor JOKFNDED_01566 240016.ABIZ01000001_gene347 4.4e-102 377.9 Verrucomicrobiae atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2ITXP@203494,46SGU@74201,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex JOKFNDED_01567 240016.ABIZ01000001_gene346 6.1e-224 783.5 Verrucomicrobiae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2ITR0@203494,46SB5@74201,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit JOKFNDED_01568 1396141.BATP01000030_gene3799 6.2e-24 117.1 Verrucomicrobiae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2IUUI@203494,46TC4@74201,COG0712@1,COG0712@2 NA|NA|NA C ATP synthase delta (OSCP) subunit JOKFNDED_01569 756272.Plabr_4307 2.5e-187 661.8 Planctomycetes 3.1.3.1 ko:K01077,ko:K01113 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2J2PG@203682,COG3540@1,COG3540@2 NA|NA|NA P alkaline phosphatase D JOKFNDED_01570 240016.ABIZ01000001_gene581 6.3e-180 637.1 Verrucomicrobiae 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 2IU4V@203494,46UET@74201,COG3119@1,COG3119@2 NA|NA|NA P C-terminal region of aryl-sulfatase JOKFNDED_01571 243090.RB3919 0.0 1411.7 Planctomycetes 1.1.5.2 ko:K00117,ko:K09992 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 2IXGT@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type JOKFNDED_01574 237368.SCABRO_02994 4.2e-26 125.2 Planctomycetes Bacteria 2IZZF@203682,COG2930@1,COG2930@2 NA|NA|NA S Las17-binding protein actin regulator JOKFNDED_01575 1396141.BATP01000059_gene2510 4.1e-44 185.3 Bacteria Bacteria COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity JOKFNDED_01576 1239962.C943_02390 7.6e-34 150.2 Bacteroidetes ko:K08983 ko00000 Bacteria 4NSFQ@976,COG3556@1,COG3556@2 NA|NA|NA S Predicted membrane protein (DUF2214) JOKFNDED_01577 1396141.BATP01000058_gene2000 1.8e-72 279.3 Verrucomicrobiae gluA 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2IUC5@203494,46UVK@74201,COG1126@1,COG1126@2 NA|NA|NA E AAA domain, putative AbiEii toxin, Type IV TA system JOKFNDED_01578 443143.GM18_2860 5.6e-58 231.1 Deltaproteobacteria glnM ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1RD09@1224,2WNEQ@28221,43AIW@68525,COG0765@1,COG0765@2 NA|NA|NA P PFAM binding-protein-dependent transport systems inner membrane component JOKFNDED_01580 1396141.BATP01000028_gene2350 7.6e-32 144.4 Verrucomicrobiae Bacteria 2EKXK@1,2IUG6@203494,33EM4@2,46WCN@74201 NA|NA|NA JOKFNDED_01581 1123070.KB899257_gene2309 1.4e-58 232.6 Verrucomicrobiae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2IU7M@203494,46SQH@74201,COG0231@1,COG0231@2 NA|NA|NA J Elongation factor P (EF-P) OB domain JOKFNDED_01582 1142394.PSMK_21640 4.4e-15 88.6 Bacteria ko:K07052,ko:K09696 ko02010,ko02020,map02010,map02020 M00253 ko00000,ko00001,ko00002,ko02000 3.A.1.115 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity JOKFNDED_01583 1163408.UU9_06134 3.6e-75 289.3 Gammaproteobacteria Bacteria 1N445@1224,1RYC9@1236,COG4636@1,COG4636@2 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella JOKFNDED_01584 314230.DSM3645_13228 6.9e-94 350.9 Planctomycetes Bacteria 2DBBI@1,2IXY3@203682,2Z888@2 NA|NA|NA S YHYH protein JOKFNDED_01585 379066.GAU_1084 1.8e-98 366.3 Gemmatimonadetes yegT ko:K05820 ko00000,ko02000 2.A.1.27 Bacteria 1ZTDQ@142182,COG0477@1,COG2814@2 NA|NA|NA EGP Nucleoside H+ symporter JOKFNDED_01586 497964.CfE428DRAFT_2659 5.6e-91 341.7 Verrucomicrobia Bacteria 46SN6@74201,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 JOKFNDED_01587 1396418.BATQ01000012_gene4453 2.5e-117 428.7 Verrucomicrobiae ko:K03924 ko00000,ko01000 Bacteria 2IU6T@203494,46S8X@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_01588 240016.ABIZ01000001_gene4334 4.4e-22 111.3 Bacteria folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria COG0262@1,COG0262@2 NA|NA|NA H dihydrofolate reductase activity JOKFNDED_01589 1121930.AQXG01000003_gene2642 1.2e-25 123.6 Bacteria dedA Bacteria COG0586@1,COG0586@2 NA|NA|NA S FtsZ-dependent cytokinesis JOKFNDED_01590 240016.ABIZ01000001_gene4217 8.2e-65 255.0 Verrucomicrobiae Bacteria 2ITZJ@203494,46V9U@74201,COG1657@1,COG1657@2 NA|NA|NA I Prenyltransferase and squalene oxidase repeat JOKFNDED_01592 1396418.BATQ01000168_gene1815 7.7e-36 156.8 Verrucomicrobiae 5.3.3.19 ko:K19547 ko01130,map01130 M00787 ko00000,ko00001,ko00002,ko01000 Bacteria 2IW7Z@203494,46VSQ@74201,COG0662@1,COG0662@2 NA|NA|NA G Cupin domain JOKFNDED_01593 1403819.BATR01000127_gene4526 9.4e-164 583.2 Verrucomicrobiae ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 2ITV0@203494,46S5K@74201,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H GTP cyclohydrolase II JOKFNDED_01594 1396418.BATQ01000145_gene3539 3.1e-08 64.7 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01595 926550.CLDAP_14210 5e-98 364.0 Chloroflexi dys 2.5.1.46 ko:K00809 ko00000,ko01000 Bacteria 2G7R7@200795,COG1899@1,COG1899@2 NA|NA|NA O PFAM deoxyhypusine synthase JOKFNDED_01597 395961.Cyan7425_1430 9.3e-10 70.1 Bacteria Bacteria 2CEFP@1,2ZGIZ@2 NA|NA|NA JOKFNDED_01598 1396141.BATP01000030_gene3553 3.8e-32 145.6 Verrucomicrobia ko:K15270 ko00000,ko02000 2.A.7.3.7 Bacteria 46WBH@74201,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family JOKFNDED_01599 404380.Gbem_2483 1.1e-58 233.8 delta/epsilon subdivisions 2.7.1.15,2.7.1.184 ko:K00852,ko:K18478 ko00030,map00030 R01051,R02750,R10970 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MUUC@1224,42M1U@68525,COG0524@1,COG0524@2 NA|NA|NA G PFAM PfkB domain protein JOKFNDED_01601 382464.ABSI01000013_gene1924 5.9e-07 60.1 Verrucomicrobiae Bacteria 2IUTG@203494,46W4S@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_01602 717785.HYPMC_3134 3.9e-85 322.0 Hyphomicrobiaceae bme6 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1MWEM@1224,2U1NW@28211,3N8M7@45401,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain JOKFNDED_01603 439375.Oant_3378 3.5e-12 78.6 Brucellaceae Bacteria 1J2V2@118882,1N0XR@1224,2UEI0@28211,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain JOKFNDED_01604 240016.ABIZ01000001_gene1067 7.8e-71 273.9 Bacteria ko:K12984 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 JOKFNDED_01605 1317124.DW2_18039 5.5e-62 244.2 Alphaproteobacteria 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 1RAQ6@1224,2U62S@28211,COG2227@1,COG2227@2 NA|NA|NA H Mycolic acid cyclopropane synthetase JOKFNDED_01607 1353537.TP2_17385 2e-56 225.3 Thioclava wcaF 2.3.1.79 ko:K00661,ko:K03818 ko00000,ko01000 Bacteria 1R6A3@1224,2UEII@28211,2XPFU@285107,COG0110@1,COG0110@2 NA|NA|NA S acetyltransferase (isoleucine patch superfamily) JOKFNDED_01609 583355.Caka_2484 7.3e-70 270.8 Opitutae Bacteria 3K7G6@414999,46SWH@74201,COG1082@1,COG1082@2 NA|NA|NA G PFAM Xylose isomerase domain protein TIM barrel JOKFNDED_01611 1219375.CM002139_gene2473 6.8e-87 327.4 Xanthomonadales cdh2 1.1.1.412 ko:K22320 ko00000,ko01000 Bacteria 1R5R5@1224,1RY16@1236,1XA39@135614,COG0451@1,COG0451@2 NA|NA|NA GM NAD(P)h steroid dehydrogenase JOKFNDED_01612 1123070.KB899247_gene1458 4.1e-27 128.3 Verrucomicrobiae nadD 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IUSZ@203494,46YSF@74201,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) JOKFNDED_01613 1396418.BATQ01000011_gene4472 7.6e-31 139.8 Verrucomicrobiae trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2IW75@203494,46XMK@74201,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin-like domain JOKFNDED_01614 382464.ABSI01000010_gene3622 1.3e-172 613.6 Verrucomicrobiae Bacteria 2IVAK@203494,46SJD@74201,COG0551@1,COG0551@2 NA|NA|NA L Protein of unknown function (DUF1587) JOKFNDED_01616 1396141.BATP01000023_gene686 3.7e-193 681.4 Verrucomicrobiae 3.6.3.38 ko:K07214,ko:K09689,ko:K14274 ko00040,ko02010,map00040,map02010 M00249 R02427 RC00713 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101 Bacteria 2IVG9@203494,46TMI@74201,COG2382@1,COG2382@2,COG3386@1,COG3386@2 NA|NA|NA GP SMP-30/Gluconolaconase/LRE-like region JOKFNDED_01617 497964.CfE428DRAFT_2492 7.1e-32 144.8 Bacteria ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria COG0501@1,COG0501@2 NA|NA|NA O metalloendopeptidase activity JOKFNDED_01619 1403819.BATR01000002_gene61 3.9e-77 295.8 Verrucomicrobiae tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2IW0H@203494,46SNJ@74201,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase family 4 JOKFNDED_01620 1396141.BATP01000020_gene28 9.1e-11 75.1 Bacteria ko:K20920 ko05111,map05111 ko00000,ko00001,ko02000 1.B.66.3.1,1.B.66.3.2 Bacteria COG5338@1,COG5338@2 NA|NA|NA P Protein conserved in bacteria JOKFNDED_01626 768671.ThimaDRAFT_1948 1.6e-45 190.3 Chromatiales Bacteria 1RGI6@1224,1S85X@1236,1X13Z@135613,COG4424@1,COG4424@2 NA|NA|NA S Sulfotransferase family JOKFNDED_01627 240016.ABIZ01000001_gene3349 2.4e-22 112.5 Verrucomicrobia Bacteria 2BNE4@1,2ZUA2@2,46WGV@74201 NA|NA|NA JOKFNDED_01628 240016.ABIZ01000001_gene5803 1.5e-38 166.0 Verrucomicrobiae mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 ko:K02428,ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 Bacteria 2ITIM@203494,46SNM@74201,COG1694@1,COG3956@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase domain JOKFNDED_01629 497964.CfE428DRAFT_3657 2.1e-68 265.8 Verrucomicrobia rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 46SZQ@74201,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit JOKFNDED_01630 1396141.BATP01000059_gene2545 1.7e-33 150.2 Bacteria Bacteria COG1073@1,COG1073@2 NA|NA|NA S thiolester hydrolase activity JOKFNDED_01631 756272.Plabr_2394 8.6e-139 500.7 Planctomycetes Bacteria 2IYDP@203682,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein JOKFNDED_01632 1396141.BATP01000009_gene2650 9.4e-128 463.4 Verrucomicrobiae Bacteria 2ITSJ@203494,46SBW@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain JOKFNDED_01634 123214.PERMA_0403 5.4e-117 427.6 Aquificae lspL 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 R01385 RC00289 ko00000,ko00001,ko01000 Bacteria 2G3NS@200783,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase JOKFNDED_01636 344747.PM8797T_07679 6.7e-127 461.1 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_01637 240016.ABIZ01000001_gene389 2.5e-141 508.4 Verrucomicrobiae ilvC 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITY3@203494,46SI2@74201,COG0059@1,COG0059@2 NA|NA|NA E Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate JOKFNDED_01638 641491.DND132_0392 4e-103 381.7 Desulfovibrionales nifS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1MU1C@1224,2M92B@213115,2WIR6@28221,42M5V@68525,COG1104@1,COG1104@2 NA|NA|NA E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine JOKFNDED_01639 1396141.BATP01000058_gene1954 4.7e-94 351.7 Verrucomicrobiae folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K01932,ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2475,iJN746.PP_1997,iSDY_1059.SDY_2514 Bacteria 2ITNW@203494,46SKD@74201,COG0285@1,COG0285@2 NA|NA|NA H Mur ligase middle domain JOKFNDED_01640 497964.CfE428DRAFT_3278 1.4e-106 393.3 Verrucomicrobia Bacteria 46U7V@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_01641 1122919.KB905607_gene4634 1.7e-23 117.1 Paenibacillaceae 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 1UZJR@1239,26WK7@186822,4I7ER@91061,COG4409@1,COG4409@2,COG4692@1,COG4692@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_01643 1403819.BATR01000051_gene1461 2.4e-204 719.2 Verrucomicrobiae Bacteria 2IWNW@203494,46UH6@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1587) JOKFNDED_01644 243090.RB10999 2.6e-127 463.4 Planctomycetes 3.2.1.18,3.2.1.4 ko:K01179,ko:K01186 ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142 R04018,R06200,R11307,R11308 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33,GH5,GH9 Bacteria 2J1WK@203682,COG4409@1,COG4409@2 NA|NA|NA M BNR repeat-like domain JOKFNDED_01645 1396418.BATQ01000184_gene2629 3.1e-152 545.8 Bacteria Bacteria 2DENQ@1,2ZNKW@2 NA|NA|NA JOKFNDED_01647 419947.MRA_0249 6.9e-24 117.1 Bacteria vapC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07064 ko00000 Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_01648 794903.OPIT5_12135 3.7e-16 93.6 Bacteria Bacteria COG5434@1,COG5434@2 NA|NA|NA M polygalacturonase activity JOKFNDED_01649 497964.CfE428DRAFT_1814 0.0 1255.0 Bacteria ko:K09992 ko00000 Bacteria COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG3828@1,COG3828@2 NA|NA|NA N Trehalose utilisation JOKFNDED_01650 756272.Plabr_2988 1.1e-10 74.3 Bacteria Bacteria COG3712@1,COG3712@2 NA|NA|NA PT iron ion homeostasis JOKFNDED_01651 756272.Plabr_2989 9e-50 203.4 Bacteria rfaY ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_01652 886293.Sinac_6731 1.8e-95 355.9 Planctomycetes aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K00014,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 2J1XX@203682,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) JOKFNDED_01654 1396141.BATP01000005_gene6079 3.2e-47 195.7 Verrucomicrobia ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 46U5D@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_01655 743719.PaelaDRAFT_4069 1.2e-06 61.6 Bacilli 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 1TQRX@1239,4HEUW@91061,COG0265@1,COG0265@2,COG2010@1,COG2010@2,COG4409@1,COG4409@2 NA|NA|NA G An automated process has identified a potential problem with this gene model JOKFNDED_01656 1396141.BATP01000006_gene5485 1.1e-132 479.9 Verrucomicrobiae deoA GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 Bacteria 2IV5J@203494,46X9Z@74201,COG0213@1,COG0213@2 NA|NA|NA F Pyrimidine nucleoside phosphorylase C-terminal domain JOKFNDED_01657 243232.MJ_1500 4.5e-15 88.6 Archaea Archaea arCOG08288@1,arCOG08288@2157 NA|NA|NA JOKFNDED_01658 240016.ABIZ01000001_gene4899 1.7e-86 326.6 Verrucomicrobiae Bacteria 2IUDZ@203494,46WD7@74201,COG3271@1,COG3271@2 NA|NA|NA JOKFNDED_01659 1123070.KB899255_gene1386 9.9e-138 496.5 Verrucomicrobiae dhaL 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVDJ@203494,46V9H@74201,COG1461@1,COG1461@2,COG2376@1,COG2376@2 NA|NA|NA G Dak1 domain JOKFNDED_01660 240016.ABIZ01000001_gene2967 2e-48 199.1 Verrucomicrobia dhaL 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 46W0Y@74201,COG1461@1,COG1461@2 NA|NA|NA S Dak2 JOKFNDED_01661 671143.DAMO_0801 4.4e-08 63.5 Bacteria coxA2 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria COG0843@1,COG0843@2 NA|NA|NA C heme-copper terminal oxidase activity JOKFNDED_01662 671143.DAMO_0797 2.9e-28 132.5 unclassified Bacteria ko:K07152 ko00000,ko03029 Bacteria 2NP9U@2323,COG1999@1,COG1999@2 NA|NA|NA S signal sequence binding JOKFNDED_01663 746697.Aeqsu_2902 3.1e-36 158.3 Flavobacteriia azu GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009767,GO:0009987,GO:0015979,GO:0016020,GO:0019684,GO:0022900,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071944 Bacteria 1I34Z@117743,4NQ6P@976,COG3241@1,COG3241@2 NA|NA|NA C PFAM Copper binding proteins, plastocyanin azurin family JOKFNDED_01664 1396141.BATP01000057_gene3038 1.3e-59 236.5 Verrucomicrobiae Bacteria 2IV5E@203494,46WKE@74201,COG3448@1,COG3448@2 NA|NA|NA T HPP family JOKFNDED_01665 497964.CfE428DRAFT_2739 2.8e-35 154.8 Bacteria ko:K06886 ko00000 Bacteria COG2346@1,COG2346@2 NA|NA|NA O COG2346, Truncated hemoglobins JOKFNDED_01666 313628.LNTAR_17648 2.6e-44 186.4 Bacteria Bacteria COG1874@1,COG1874@2 NA|NA|NA G beta-galactosidase activity JOKFNDED_01667 1403819.BATR01000125_gene4449 7e-77 294.3 Bacteria Bacteria 2CEMG@1,346QA@2 NA|NA|NA JOKFNDED_01668 1396141.BATP01000006_gene5477 1.1e-22 112.8 Verrucomicrobiae Bacteria 2IV8Z@203494,46TDA@74201,COG1680@1,COG1680@2,COG3876@1,COG3876@2 NA|NA|NA V Beta-lactamase JOKFNDED_01669 1396141.BATP01000047_gene3974 1.2e-118 433.3 Verrucomicrobiae Bacteria 2IW2Y@203494,46XJK@74201,COG4299@1,COG4299@2 NA|NA|NA S Domain of unknown function (DUF5009) JOKFNDED_01671 767817.Desgi_1747 7.1e-68 265.0 Bacteria 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria COG0399@1,COG0399@2 NA|NA|NA E UDP-4-amino-4-deoxy-L-arabinose aminotransferase JOKFNDED_01672 1396141.BATP01000023_gene606 1.3e-200 706.1 Verrucomicrobiae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITWU@203494,46U3N@74201,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA JOKFNDED_01673 1519464.HY22_11920 1.9e-58 233.8 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_01674 1123070.KB899249_gene287 5.5e-124 450.7 Verrucomicrobiae lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2ITX7@203494,46TZG@74201,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives JOKFNDED_01675 926550.CLDAP_08980 6.2e-133 480.7 Chloroflexi mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 Bacteria 2G5Z3@200795,COG0182@1,COG0182@2 NA|NA|NA J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) JOKFNDED_01676 1403819.BATR01000134_gene4799 2.8e-43 182.2 Verrucomicrobiae pilD 3.4.23.43 ko:K02236,ko:K02278,ko:K02506,ko:K02654,ko:K10966 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 2IU6Y@203494,46TWT@74201,COG1989@1,COG1989@2 NA|NA|NA NOU Type IV leader peptidase family JOKFNDED_01677 1123070.KB899248_gene116 1.2e-31 143.3 Verrucomicrobiae Bacteria 2ITZE@203494,46SPP@74201,COG0591@1,COG0591@2 NA|NA|NA E Sodium:solute symporter family JOKFNDED_01678 1403819.BATR01000094_gene2918 2.6e-111 409.1 Verrucomicrobia ko:K08194 ko00000,ko02000 2.A.1.14.7 Bacteria 46U5B@74201,COG2271@1,COG2271@2 NA|NA|NA G Sugar (and other) transporter JOKFNDED_01679 1453503.AU05_12090 2.4e-154 553.1 Gammaproteobacteria mrpA GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05559,ko:K05565 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1MW2M@1224,1RNKN@1236,COG1009@1,COG1009@2,COG2111@1,COG2111@2 NA|NA|NA CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit JOKFNDED_01680 313628.LNTAR_05984 3.8e-17 94.4 Bacteria mrpC ko:K05567 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria COG1006@1,COG1006@2 NA|NA|NA P Multisubunit Na H antiporter MnhC subunit JOKFNDED_01681 1397528.Q671_10005 5.1e-111 408.3 Oceanospirillales mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05568 ko00000,ko02000 2.A.63.1,2.A.63.2 iSB619.SA_RS04615 Bacteria 1MURB@1224,1RQBG@1236,1XHVS@135619,COG0651@1,COG0651@2 NA|NA|NA CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit JOKFNDED_01682 189425.PGRAT_12420 2e-10 72.0 Paenibacillaceae mrpE ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1V52M@1239,26XFI@186822,4HI4G@91061,COG1863@1,COG1863@2 NA|NA|NA P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali JOKFNDED_01683 1089550.ATTH01000001_gene370 3.2e-07 61.2 Bacteroidetes Order II. Incertae sedis mnhF ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1FKCH@1100069,4NT1B@976,COG2212@1,COG2212@2 NA|NA|NA P Multiple resistance and pH regulation protein F (MrpF / PhaF) JOKFNDED_01684 935839.JAGJ01000001_gene1255 1.4e-11 75.5 Promicromonosporaceae mrpG ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 2IQXD@201174,4F4WM@85017,COG1320@1,COG1320@2 NA|NA|NA P Na+/H+ antiporter subunit JOKFNDED_01685 1333523.L593_04990 2.5e-27 131.0 Halobacteria aglB GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0045229,GO:0045232,GO:0071840 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 GT66 Archaea 23SCX@183963,2XU8G@28890,COG1287@1,arCOG02043@2157 NA|NA|NA S membrane protein, required for N-linked glycosylation JOKFNDED_01687 257313.BP0977 1.7e-116 426.0 Alcaligenaceae tas Bacteria 1MV2Y@1224,2VI7D@28216,3T1DR@506,COG0667@1,COG0667@2 NA|NA|NA C oxidoreductases (related to aryl-alcohol dehydrogenases) JOKFNDED_01688 497964.CfE428DRAFT_5651 1.8e-18 99.4 Verrucomicrobia Bacteria 2FKI6@1,34C5C@2,46W75@74201 NA|NA|NA JOKFNDED_01689 1150599.MPHLEI_17120 2.5e-29 136.0 Mycobacteriaceae Bacteria 23507@1762,2I4EQ@201174,COG4328@1,COG4328@2 NA|NA|NA S Protein of unknown function (DUF429) JOKFNDED_01690 448385.sce1328 1e-25 123.2 Myxococcales ko:K07071 ko00000 Bacteria 1R0BS@1224,2X81U@28221,2Z3JC@29,43CU7@68525,COG4276@1,COG4276@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport JOKFNDED_01691 1123070.KB899247_gene1556 4.4e-100 371.7 Verrucomicrobiae hemY Bacteria 2IV7P@203494,46XAQ@74201,COG1232@1,COG1232@2 NA|NA|NA H Flavin containing amine oxidoreductase JOKFNDED_01692 240016.ABIZ01000001_gene379 6.4e-23 115.9 Bacteria 3.1.3.8 ko:K01083,ko:K02519 ko00562,map00562 R03371 RC00078 ko00000,ko00001,ko01000,ko03012,ko03029 Bacteria COG5164@1,COG5164@2 NA|NA|NA K cell wall organization JOKFNDED_01694 756272.Plabr_3159 1.7e-96 359.4 Planctomycetes rbsB ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2J2R0@203682,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain JOKFNDED_01696 1403819.BATR01000137_gene4876 1.9e-22 113.6 Verrucomicrobiae ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2IUSI@203494,46T4T@74201,COG1589@1,COG1589@2 NA|NA|NA M POTRA domain, FtsQ-type JOKFNDED_01697 349741.Amuc_0661 8.2e-91 340.5 Verrucomicrobiae ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.1.2.1,6.3.2.35,6.3.2.4,6.3.2.8 ko:K00075,ko:K01921,ko:K01924,ko:K15739,ko:K18856 ko00471,ko00473,ko00520,ko00550,ko01100,ko01502,ko02020,map00471,map00473,map00520,map00550,map01100,map01502,map02020 M00651,M00652 R01150,R03191,R03192,R03193,R09588 RC00037,RC00064,RC00094,RC00141,RC02639 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0095,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2IU29@203494,46UZ2@74201,COG1181@1,COG1181@2 NA|NA|NA M D-ala D-ala ligase N-terminus JOKFNDED_01699 497964.CfE428DRAFT_3349 4.1e-12 77.4 Verrucomicrobia Bacteria 293G7@1,2ZQYH@2,46WT2@74201 NA|NA|NA JOKFNDED_01700 1396418.BATQ01000085_gene1128 1.9e-64 252.3 Verrucomicrobiae murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4,6.3.2.8 ko:K00075,ko:K01921,ko:K01924 ko00471,ko00473,ko00520,ko00550,ko01100,ko01502,map00471,map00473,map00520,map00550,map01100,map01502 R01150,R03191,R03192,R03193 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 iIT341.HP1418,iYO844.BSU15230 Bacteria 2ITNT@203494,46SCG@74201,COG0773@1,COG0773@2,COG0812@1,COG0812@2 NA|NA|NA M UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain JOKFNDED_01704 794903.OPIT5_28470 3.8e-124 451.1 Opitutae ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 3K7TY@414999,46SNF@74201,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter JOKFNDED_01705 1396141.BATP01000056_gene3232 4.4e-116 424.9 Verrucomicrobiae 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 2IV13@203494,46SDX@74201,COG1134@1,COG1134@2 NA|NA|NA GM ATPases associated with a variety of cellular activities JOKFNDED_01706 113355.CM001775_gene178 2.7e-58 232.3 Bacteria Bacteria COG2242@1,COG2242@2 NA|NA|NA H protein methyltransferase activity JOKFNDED_01707 113355.CM001775_gene170 4.1e-82 312.0 Cyanobacteria Bacteria 1G8NA@1117,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_01708 489825.LYNGBM3L_50410 4.2e-61 241.9 Oscillatoriales ggaB Bacteria 1G54W@1117,1HAN9@1150,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 JOKFNDED_01709 1173027.Mic7113_5736 6.5e-22 111.3 Oscillatoriales Bacteria 1G543@1117,1HD58@1150,COG2242@1,COG2242@2 NA|NA|NA H Methyltransferase FkbM domain JOKFNDED_01710 309803.CTN_0032 4.1e-40 171.4 Thermotogae rfbC 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 2GDVU@200918,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose JOKFNDED_01711 1173028.ANKO01000018_gene1167 1.9e-55 223.0 Oscillatoriales galE7 1.1.1.339 ko:K19180 ko00523,ko01130,map00523,map01130 R10190 RC00182 ko00000,ko00001,ko01000 Bacteria 1G3KY@1117,1HBRG@1150,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase dehydratase family JOKFNDED_01712 426355.Mrad2831_1221 4.2e-79 302.0 Methylobacteriaceae ko:K16437,ko:K20331,ko:K21336 ko00523,ko01055,ko01130,ko02024,map00523,map01055,map01130,map02024 R06627,R11466 RC00003,RC01654,RC03444 ko00000,ko00001,ko01000 Bacteria 1JZIZ@119045,1QW8Z@1224,2TWTG@28211,COG4976@1,COG4976@2 NA|NA|NA H C-methyltransferase C-terminal domain JOKFNDED_01713 489825.LYNGBM3L_50420 3.5e-44 186.0 Bacteria ko:K20999 ko02025,map02025 ko00000,ko00001,ko01003 GT4 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_01714 489825.LYNGBM3L_50440 8.8e-49 200.7 Bacteria fkbM Bacteria COG4123@1,COG4123@2 NA|NA|NA AJ Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) JOKFNDED_01715 489825.LYNGBM3L_50430 2.7e-62 246.1 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_01716 765911.Thivi_4045 2e-106 392.5 Bacteria hddA 2.7.1.168 ko:K07031 ko00540,map00540 R09770 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria COG2605@1,COG2605@2 NA|NA|NA G GHMP kinase JOKFNDED_01717 526227.Mesil_0238 6.2e-107 394.4 Deinococcus-Thermus gmhB 2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83 ko:K00966,ko:K03273,ko:K15669 ko00051,ko00520,ko00540,ko01100,ko01110,map00051,map00520,map00540,map01100,map01110 M00064,M00114,M00361,M00362 R00885,R05647,R09771,R09772 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1WM0S@1297,COG0241@1,COG0241@2,COG1208@1,COG1208@2 NA|NA|NA JM COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) JOKFNDED_01718 489825.LYNGBM3L_50450 1.6e-59 235.7 Oscillatoriales 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1G8ZT@1117,1HD90@1150,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (three repeats) JOKFNDED_01721 794903.OPIT5_10300 5.1e-56 224.9 Opitutae ko:K03466,ko:K07088 ko00000,ko03036 3.A.12 Bacteria 3K77N@414999,46SPM@74201,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein JOKFNDED_01722 870187.Thini_0381 2.1e-07 63.2 Bacteria Bacteria 2DPRN@1,33341@2 NA|NA|NA JOKFNDED_01723 1121904.ARBP01000003_gene6435 2.1e-96 359.8 Cytophagia dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 47K1Y@768503,4NGIQ@976,COG2027@1,COG2027@2 NA|NA|NA M PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C JOKFNDED_01724 240016.ABIZ01000001_gene266 6e-56 224.6 Verrucomicrobia Bacteria 28NEV@1,32VKA@2,46UC0@74201 NA|NA|NA JOKFNDED_01725 1150469.RSPPHO_02241 1.1e-38 166.8 Rhodospirillales 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1RJBG@1224,2JWKY@204441,2TVMH@28211,COG0860@1,COG0860@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase JOKFNDED_01726 452637.Oter_2076 2.7e-17 96.3 Opitutae ctaA ko:K02259,ko:K03110 ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714 M00154,M00335 R07412 RC00769 ko00000,ko00001,ko00002,ko02044,ko03029 3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4 Bacteria 3K7WI@414999,46T3F@74201,COG1612@1,COG1612@2 NA|NA|NA O cytochrome oxidase assembly JOKFNDED_01727 1123070.KB899256_gene2171 7.8e-73 280.8 Verrucomicrobiae ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 iJN746.PP_0110,iSB619.SA_RS05465,iSFxv_1172.SFxv_0410,iYO844.BSU12080 Bacteria 2IU7F@203494,46SQE@74201,COG0109@1,COG0109@2 NA|NA|NA O UbiA prenyltransferase family JOKFNDED_01728 1396418.BATQ01000041_gene6306 4e-24 118.6 Verrucomicrobiae ko:K07152 ko00000,ko03029 Bacteria 2IW6S@203494,46VZB@74201,COG1999@1,COG1999@2 NA|NA|NA S SCO1/SenC JOKFNDED_01729 478741.JAFS01000002_gene876 1.6e-30 140.6 unclassified Verrucomicrobia yozB ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 37GQA@326457,46SZT@74201,COG2322@1,COG2322@2 NA|NA|NA S Protein of unknown function (DUF420) JOKFNDED_01730 1403819.BATR01000114_gene3951 5.9e-16 90.5 Verrucomicrobiae Bacteria 2IUWC@203494,46T32@74201,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like domain JOKFNDED_01731 329726.AM1_2737 4.9e-11 74.3 Cyanobacteria Bacteria 1GGD4@1117,COG2105@1,COG2105@2 NA|NA|NA S Gamma-glutamyl cyclotransferase, AIG2-like JOKFNDED_01733 1249627.D779_0107 2.1e-119 436.0 Chromatiales rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5E@1224,1RP7G@1236,1WX1W@135613,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily JOKFNDED_01734 522306.CAP2UW1_0197 1.3e-115 422.5 Betaproteobacteria 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 1MUJH@1224,2VNDQ@28216,COG3119@1,COG3119@2 NA|NA|NA P Arylsulfatase JOKFNDED_01735 522306.CAP2UW1_0198 1.9e-130 472.2 Betaproteobacteria Bacteria 1MW38@1224,2VN83@28216,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase JOKFNDED_01737 240016.ABIZ01000001_gene266 1.9e-57 229.6 Verrucomicrobia Bacteria 28NEV@1,32VKA@2,46UC0@74201 NA|NA|NA JOKFNDED_01738 1403819.BATR01000176_gene5944 2.8e-55 222.6 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01739 1279038.KB907339_gene1275 3e-44 185.7 Rhodospirillales 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1RJBG@1224,2JWKY@204441,2TVMH@28211,COG0860@1,COG0860@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase JOKFNDED_01740 107635.AZUO01000001_gene2818 1.3e-134 486.9 Methylocystaceae tldD ko:K03568 ko00000,ko01002 Bacteria 1MUSK@1224,2TRSR@28211,36YJP@31993,COG0312@1,COG0312@2 NA|NA|NA S Putative modulator of DNA gyrase JOKFNDED_01741 1198452.Jab_1c06730 3e-86 325.9 Oxalobacteraceae tldD3 Bacteria 1PWJP@1224,2WC44@28216,476YN@75682,COG0312@1,COG0312@2 NA|NA|NA S Putative modulator of DNA gyrase JOKFNDED_01742 1396418.BATQ01000175_gene2770 1.1e-14 85.9 Bacteria comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria COG1555@1,COG1555@2 NA|NA|NA L photosystem II stabilization JOKFNDED_01743 243090.RB5577 1.7e-76 293.1 Planctomycetes 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IXCR@203682,COG3386@1,COG3386@2 NA|NA|NA G SMP-30/Gluconolaconase/LRE-like region JOKFNDED_01744 1396418.BATQ01000088_gene1037 2e-34 152.1 Verrucomicrobia Bacteria 46SZI@74201,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) JOKFNDED_01745 1266925.JHVX01000008_gene261 1.9e-55 222.6 Nitrosomonadales Bacteria 1QZ0R@1224,2WHHC@28216,374RD@32003,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain JOKFNDED_01746 756272.Plabr_2893 9.6e-38 163.7 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity JOKFNDED_01747 1403819.BATR01000050_gene1450 3.4e-90 338.2 Verrucomicrobiae 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2IUD0@203494,46SNZ@74201,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family JOKFNDED_01750 639030.JHVA01000001_gene3731 4.8e-26 124.4 Bacteria crtO ko:K10212 ko00906,map00906 R07656 RC00041 ko00000,ko00001,ko01000 Bacteria 2E9V0@1,3340V@2 NA|NA|NA S carotenoid biosynthetic process JOKFNDED_01751 1123070.KB899253_gene991 6.8e-76 291.2 Verrucomicrobiae crtQ ko:K10211 ko00906,map00906 R07655 RC00523 ko00000,ko00001,ko01000 Bacteria 2IVN1@203494,46WX3@74201,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 21 JOKFNDED_01752 1123070.KB899253_gene992 4.5e-195 687.6 Verrucomicrobiae crtP 1.14.99.44 ko:K10210 ko00906,map00906 R07654,R09671,R09727,R09728 RC00254,RC02089,RC02626,RC02638 ko00000,ko00001,ko01000 Bacteria 2IVA7@203494,46SE8@74201,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase JOKFNDED_01753 491915.Aflv_2201 5.9e-153 547.7 Bacilli carC 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 1TS4A@1239,4HB9J@91061,COG1233@1,COG1233@2 NA|NA|NA Q COG1233 Phytoene dehydrogenase and related proteins JOKFNDED_01754 582515.KR51_00001230 3.1e-110 405.6 Cyanobacteria 1.2.1.3,1.2.1.5 ko:K00128,ko:K00129 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735 ko00000,ko00001,ko00002,ko01000 Bacteria 1G2U1@1117,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family JOKFNDED_01755 756272.Plabr_2090 4.9e-67 261.2 Planctomycetes Bacteria 2IZGT@203682,COG4099@1,COG4099@2 NA|NA|NA P Phospholipase/Carboxylesterase JOKFNDED_01756 1120983.KB894570_gene1888 6.2e-18 98.2 Alphaproteobacteria cpdA 2.1.2.2,3.1.4.53 ko:K03651,ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025 M00048 R00191,R04325,R04326 RC00026,RC00197,RC00296,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWKX@1224,2U5HA@28211,COG1409@1,COG1409@2 NA|NA|NA G Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes JOKFNDED_01757 240016.ABIZ01000001_gene5894 3.7e-43 181.4 Verrucomicrobiae gmhB 2.7.7.71,3.1.3.82,3.1.3.83 ko:K03273,ko:K15669 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771,R09772 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IW66@203494,46T3Q@74201,COG0241@1,COG0241@2 NA|NA|NA E Polynucleotide kinase 3 phosphatase JOKFNDED_01758 497964.CfE428DRAFT_2713 1.1e-160 573.2 Verrucomicrobia clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 46SIK@74201,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP JOKFNDED_01761 240016.ABIZ01000001_gene917 2.6e-108 399.1 Verrucomicrobia Bacteria 46Z50@74201,COG3507@1,COG3507@2 NA|NA|NA G Belongs to the glycosyl hydrolase 43 family JOKFNDED_01763 1396141.BATP01000022_gene449 2.3e-175 623.6 Verrucomicrobiae psrP1 ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IVDX@203494,46TW3@74201,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3468@1,COG3468@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase JOKFNDED_01764 1380391.JIAS01000012_gene4258 2.9e-49 203.4 Rhodospirillales MA20_39250 Bacteria 1MXFD@1224,2JWIY@204441,2TR94@28211,COG4249@1,COG4249@2 NA|NA|NA S Caspase domain JOKFNDED_01765 497964.CfE428DRAFT_5343 7.7e-33 148.7 Verrucomicrobia Bacteria 2EZMG@1,33SSM@2,46UUT@74201 NA|NA|NA JOKFNDED_01766 1396418.BATQ01000125_gene5093 1.1e-66 260.8 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01767 240016.ABIZ01000001_gene1209 1.1e-45 189.5 Verrucomicrobiae ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 2IUDM@203494,46VKB@74201,COG0105@1,COG0105@2 NA|NA|NA F NDK JOKFNDED_01769 1403819.BATR01000094_gene2991 7.3e-106 391.0 Verrucomicrobia Bacteria 28HUC@1,2Z811@2,46TJ5@74201 NA|NA|NA JOKFNDED_01770 240016.ABIZ01000001_gene4894 2.2e-165 589.7 Verrucomicrobiae galA Bacteria 2IV9B@203494,46US8@74201,COG3420@1,COG3420@2 NA|NA|NA P Right handed beta helix region JOKFNDED_01771 240016.ABIZ01000001_gene3243 1e-184 653.3 Verrucomicrobiae Bacteria 2IWP5@203494,46Z3Q@74201,COG0492@1,COG0492@2 NA|NA|NA O FAD dependent oxidoreductase JOKFNDED_01773 1121396.KB893012_gene4111 7e-62 244.2 Deltaproteobacteria Bacteria 1MX0V@1224,2X5IM@28221,42QVS@68525,COG3177@1,COG3177@2 NA|NA|NA S PFAM Filamentation induced by cAMP death on curing, related JOKFNDED_01774 521674.Plim_0121 5.8e-177 627.1 Planctomycetes Bacteria 2A5IZ@1,2J2QZ@203682,30U97@2 NA|NA|NA JOKFNDED_01775 240016.ABIZ01000001_gene1568 4.3e-111 407.9 Verrucomicrobiae pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_0056 Bacteria 2IWMA@203494,46TI8@74201,COG1995@1,COG1995@2 NA|NA|NA H Pyridoxal phosphate biosynthetic protein PdxA JOKFNDED_01776 452637.Oter_2151 3.5e-58 232.3 Bacteria 2.7.1.219,2.7.1.220 ko:K22129 ko00000,ko01000 Bacteria COG3395@1,COG3395@2 NA|NA|NA S kinase activity JOKFNDED_01777 497964.CfE428DRAFT_3829 2.9e-87 328.6 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity JOKFNDED_01778 378806.STAUR_0232 9e-10 71.2 Myxococcales ko:K00612 ko00000,ko01000 Bacteria 1QM85@1224,2X7E6@28221,2YVUF@29,43C3I@68525,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_01779 886293.Sinac_1155 1e-66 261.2 Planctomycetes moxJ ko:K06867 ko00000 Bacteria 2J1F8@203682,COG0666@1,COG0666@2 NA|NA|NA S Ankyrin repeat JOKFNDED_01780 886293.Sinac_1154 5.5e-173 614.0 Planctomycetes ko:K09806 ko00000 Bacteria 2J2KP@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_01781 1403819.BATR01000180_gene5992 6.6e-120 438.3 Verrucomicrobia Bacteria 46SS5@74201,COG3525@1,COG3525@2 NA|NA|NA G Domain of unknown function (DUF4838) JOKFNDED_01783 886293.Sinac_1153 5.4e-218 764.2 Bacteria 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria COG0551@1,COG0551@2 NA|NA|NA L DNA topological change JOKFNDED_01784 686340.Metal_0565 1e-40 173.7 Methylococcales 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4,3.1.21.3 ko:K00543,ko:K01153,ko:K16130,ko:K18896,ko:K18897,ko:K21515 ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100 M00037 R03130,R04905,R10060,R10061 RC00003,RC00392,RC03038,RC03040 ko00000,ko00001,ko00002,ko01000,ko01008,ko02048,ko03009 Bacteria 1RIWM@1224,1S7RK@1236,1XFWD@135618,COG1002@1,COG1002@2,COG1943@1,COG1943@2,COG2890@1,COG2890@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01785 1396141.BATP01000059_gene2597 3.3e-148 531.6 Verrucomicrobiae Bacteria 2IVHR@203494,46ZKH@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_01787 1396141.BATP01000059_gene2598 2.3e-234 818.9 Bacteria Bacteria COG3748@1,COG3748@2 NA|NA|NA S Urate oxidase N-terminal JOKFNDED_01789 497964.CfE428DRAFT_4845 5.1e-51 208.8 Verrucomicrobia Bacteria 46WUN@74201,COG3712@1,COG3712@2 NA|NA|NA PT FecR protein JOKFNDED_01790 595460.RRSWK_04117 3.2e-15 88.2 Bacteria rfaY ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_01791 240016.ABIZ01000001_gene379 2.7e-43 183.3 Bacteria 3.1.3.8 ko:K01083,ko:K02519 ko00562,map00562 R03371 RC00078 ko00000,ko00001,ko01000,ko03012,ko03029 Bacteria COG5164@1,COG5164@2 NA|NA|NA K cell wall organization JOKFNDED_01792 240016.ABIZ01000001_gene378 3.2e-131 474.9 Bacteria yggR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria COG2805@1,COG2805@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_01797 344747.PM8797T_04495 1.5e-75 290.0 Planctomycetes galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWRW@203682,COG2017@1,COG2017@2 NA|NA|NA G Converts alpha-aldose to the beta-anomer JOKFNDED_01798 1403819.BATR01000178_gene5964 1.8e-101 376.3 Verrucomicrobia Bacteria 46TV4@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_01799 1403819.BATR01000181_gene6081 1.8e-36 160.2 Verrucomicrobiae Bacteria 28I0W@1,2IUKF@203494,30QX6@2,46WYN@74201 NA|NA|NA JOKFNDED_01801 435591.BDI_1328 5.2e-31 140.6 Bacteroidia Bacteria 2FX5F@200643,4NF5K@976,COG3616@1,COG3616@2 NA|NA|NA E Putative serine dehydratase domain JOKFNDED_01803 344747.PM8797T_18771 9.6e-150 537.0 Planctomycetes Bacteria 2IXPB@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_01804 497964.CfE428DRAFT_3206 2.7e-144 518.8 Verrucomicrobia Bacteria 46UKF@74201,COG2133@1,COG2133@2 NA|NA|NA G pyrroloquinoline quinone binding JOKFNDED_01805 497964.CfE428DRAFT_3207 1.4e-175 623.2 Bacteria ko:K02305,ko:K07152 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko03029 3.D.4.10 Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_01806 497964.CfE428DRAFT_3208 6e-86 324.3 Verrucomicrobia Bacteria 46V05@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel JOKFNDED_01807 1403819.BATR01000096_gene3078 1.3e-83 315.8 Verrucomicrobia 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 46TH6@74201,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family JOKFNDED_01808 1173028.ANKO01000112_gene4921 5.9e-53 214.2 Oscillatoriales Bacteria 1G0VC@1117,1H7UG@1150,COG4636@1,COG4636@2 NA|NA|NA S protein conserved in cyanobacteria JOKFNDED_01809 497964.CfE428DRAFT_3210 3.2e-132 478.4 Bacteria xylR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 5.3.1.12 ko:K01812,ko:K02529,ko:K16210 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 2.A.2.5 Bacteria COG1609@1,COG1609@2,COG4977@1,COG4977@2 NA|NA|NA K sequence-specific DNA binding JOKFNDED_01811 1396418.BATQ01000010_gene3815 1.4e-137 496.5 Bacteria Bacteria COG3356@1,COG3356@2 NA|NA|NA JOKFNDED_01812 452637.Oter_2155 0.0 1932.1 Verrucomicrobia Bacteria 46U24@74201,COG2373@1,COG2373@2 NA|NA|NA S Alpha-2-macroglobulin family JOKFNDED_01813 1396141.BATP01000023_gene718 4.5e-40 170.6 Verrucomicrobiae glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 iG2583_1286.G2583_3081 Bacteria 2ITI6@203494,46S5I@74201,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism JOKFNDED_01816 1396418.BATQ01000147_gene3610 1.1e-100 374.0 Verrucomicrobiae ko:K03665 ko00000,ko03009 Bacteria 2IV0C@203494,46Z2U@74201,COG2262@1,COG2262@2 NA|NA|NA S Domain of unknown function (DUF3482) JOKFNDED_01817 420662.Mpe_A1440 8.6e-47 194.9 unclassified Burkholderiales Bacteria 1KKMU@119065,1R683@1224,28KUM@1,2VPU1@28216,2ZABC@2 NA|NA|NA S Protein of unknown function (DUF2868) JOKFNDED_01818 1396418.BATQ01000144_gene3452 7.5e-49 200.3 Verrucomicrobiae ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IUA7@203494,46T3Y@74201,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group JOKFNDED_01819 1203605.HMPREF1531_01983 6.7e-76 290.4 Actinobacteria thrH 2.7.1.39,3.1.3.3 ko:K02203 ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230 M00018 R00582,R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2H4ZQ@201174,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase JOKFNDED_01820 1396141.BATP01000040_gene2094 5.3e-40 171.0 Verrucomicrobiae sprT ko:K02742 ko00000 Bacteria 2IVYY@203494,46XI1@74201,COG3091@1,COG3091@2 NA|NA|NA S SprT homologues. JOKFNDED_01821 1396418.BATQ01000020_gene5054 7e-90 337.4 Verrucomicrobiae cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITZ0@203494,46S5J@74201,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) JOKFNDED_01822 344747.PM8797T_28729 8.6e-141 507.3 Planctomycetes 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 2IXW5@203682,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) JOKFNDED_01823 1173029.JH980292_gene1012 3.8e-09 69.7 Oscillatoriales Bacteria 1G3ES@1117,1HH3U@1150,COG3210@1,COG3210@2,COG4995@1,COG4995@2 NA|NA|NA U filamentous hemagglutinin family N-terminal domain JOKFNDED_01824 671143.DAMO_2746 1.6e-41 175.6 unclassified Bacteria ko:K07064 ko00000 Bacteria 2NRZ1@2323,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_01825 419947.MRA_3733 3.1e-07 60.8 Actinobacteria Bacteria 2A15A@1,2HCF1@201174,30PB5@2 NA|NA|NA JOKFNDED_01832 1210884.HG799473_gene14982 1.2e-67 263.8 Planctomycetes csb1 ko:K19131 ko00000,ko02048 Bacteria 28KC2@1,2J1B0@203682,2Z9Z2@2 NA|NA|NA S CRISPR-associated protein GSU0053 (Cas_GSU0053) JOKFNDED_01833 1210884.HG799473_gene14981 6.6e-51 208.8 Planctomycetes ko:K19132 ko00000,ko02048 Bacteria 2DBH6@1,2J2FW@203682,2Z97W@2 NA|NA|NA S CRISPR-associated protein, GSU0054 family (Cas_GSU0054) JOKFNDED_01834 575540.Isop_1832 9.9e-167 594.3 Planctomycetes ko:K07012 ko00000,ko01000,ko02048 Bacteria 2IXEG@203682,COG1203@1,COG1203@2 NA|NA|NA L CRISPR-associated helicase, Cas3 JOKFNDED_01835 765912.Thimo_1277 2.7e-14 86.3 Proteobacteria Bacteria 1NDIC@1224,2C1S9@1,32R0M@2 NA|NA|NA JOKFNDED_01836 1254432.SCE1572_02245 1.7e-132 479.9 Myxococcales cas1 GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0030145,GO:0034641,GO:0034655,GO:0035312,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045145,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.12.1 ko:K07464,ko:K15342 ko00000,ko01000,ko02048,ko03400 Bacteria 1MUKK@1224,2X2YF@28221,2YZFB@29,43A4J@68525,COG1468@1,COG1468@2,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette JOKFNDED_01838 1356852.N008_01195 2.7e-09 70.5 Bacteroidetes Bacteria 4PMEU@976,COG2911@1,COG2911@2,COG3391@1,COG3391@2,COG5492@1,COG5492@2 NA|NA|NA Q Concanavalin A-like lectin/glucanases superfamily JOKFNDED_01839 240016.ABIZ01000001_gene857 4.7e-20 105.5 Verrucomicrobiae Bacteria 2A569@1,2IUR2@203494,30TV5@2,46X6P@74201 NA|NA|NA JOKFNDED_01840 1230343.CANP01000050_gene3770 3.8e-21 109.8 Legionellales 3.6.3.4 ko:K01533 R00086 RC00002 ko00000,ko01000 3.A.3.5 Bacteria 1JDH3@118969,1NDDF@1224,1T3NG@1236,COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase JOKFNDED_01842 756272.Plabr_3201 3e-41 176.0 Planctomycetes Bacteria 2J2V6@203682,COG0400@1,COG0400@2 NA|NA|NA S carboxylic ester hydrolase activity JOKFNDED_01843 530564.Psta_3484 1.5e-125 456.1 Planctomycetes Bacteria 2DBUK@1,2IYA3@203682,2ZB6C@2 NA|NA|NA JOKFNDED_01844 1396141.BATP01000004_gene5923 4e-56 225.3 Verrucomicrobiae Bacteria 2IVS4@203494,46WNX@74201,COG4099@1,COG4099@2 NA|NA|NA S Phospholipase/Carboxylesterase JOKFNDED_01845 1396141.BATP01000035_gene4121 1.9e-33 148.7 Verrucomicrobiae blaI ko:K02171 ko01501,map01501 M00627 ko00000,ko00001,ko00002,ko01504,ko03000 Bacteria 2IVZW@203494,46W1S@74201,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor JOKFNDED_01846 1396141.BATP01000035_gene4118 4e-72 279.6 Verrucomicrobiae Bacteria 2IUZF@203494,46X88@74201,COG4219@1,COG4219@2 NA|NA|NA KT BlaR1 peptidase M56 JOKFNDED_01847 1403819.BATR01000031_gene1003 5.8e-105 387.5 Verrucomicrobiae 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 2IV0G@203494,46TIJ@74201,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_01848 1403819.BATR01000031_gene1022 8.9e-122 443.7 Verrucomicrobiae Bacteria 28J2H@1,2IWR3@203494,2Z90R@2,46U80@74201 NA|NA|NA JOKFNDED_01849 469381.Dpep_1232 2e-82 312.4 Synergistetes Bacteria 3TABN@508458,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_01850 240016.ABIZ01000001_gene4226 6.9e-153 547.4 Verrucomicrobiae Bacteria 2IVJJ@203494,46TYX@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_01851 314230.DSM3645_09722 3.9e-153 548.1 Planctomycetes Bacteria 2IYH5@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_01853 1396418.BATQ01000049_gene401 4.5e-30 137.5 Bacteria doc ko:K07341 ko00000,ko02048 Bacteria COG3654@1,COG3654@2 NA|NA|NA JOKFNDED_01854 583355.Caka_1235 4.7e-08 66.6 Bacteria Bacteria 2EGB6@1,33A31@2 NA|NA|NA JOKFNDED_01855 1403819.BATR01000163_gene5480 1.2e-107 397.1 Bacteria Bacteria COG3356@1,COG3356@2 NA|NA|NA JOKFNDED_01858 382464.ABSI01000005_gene1203 1.1e-216 759.2 Verrucomicrobiae leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700 Bacteria 2ITJH@203494,46SUM@74201,COG0065@1,COG0065@2 NA|NA|NA E Aconitase family (aconitate hydratase) JOKFNDED_01859 863365.XHC_2895 1.3e-36 160.6 Xanthomonadales trpI ko:K03566 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1QFR1@1224,1RMND@1236,1X4PB@135614,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator JOKFNDED_01860 1396418.BATQ01000060_gene2052 1.3e-177 630.9 Verrucomicrobiae Bacteria 2ITT7@203494,46TWC@74201,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2 NA|NA|NA CEG Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_01861 756499.Desde_3180 6.4e-39 169.5 Peptococcaceae Bacteria 1UDEK@1239,25I47@186801,26674@186807,COG5635@1,COG5635@2 NA|NA|NA T Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes JOKFNDED_01863 118166.JH976537_gene2120 7e-77 293.9 Cyanobacteria Bacteria 1GPXQ@1117,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family JOKFNDED_01865 1396418.BATQ01000039_gene6499 2.1e-17 95.9 Bacteria Bacteria 2DMJ5@1,32RXW@2 NA|NA|NA JOKFNDED_01867 925775.XVE_2419 4.6e-07 61.2 Proteobacteria Bacteria 1P1AA@1224,2EJ4R@1,33CVZ@2 NA|NA|NA JOKFNDED_01869 583355.Caka_1222 2.2e-17 95.9 Opitutae Bacteria 3KA3R@414999,46ZK6@74201,COG5523@1,COG5523@2 NA|NA|NA S Domain of unknown function (DUF4339) JOKFNDED_01870 452637.Oter_3121 1.8e-42 178.7 Verrucomicrobia Bacteria 46T3T@74201,COG3791@1,COG3791@2 NA|NA|NA S PFAM glutathione-dependent formaldehyde-activating GFA JOKFNDED_01871 1396418.BATQ01000028_gene5251 7.1e-75 289.7 Verrucomicrobiae Bacteria 2IVH7@203494,46UMT@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase JOKFNDED_01873 1519464.HY22_11920 9.8e-53 214.5 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_01875 1304885.AUEY01000096_gene2839 2.4e-120 439.9 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_01876 1396141.BATP01000029_gene2234 3.5e-49 202.2 Verrucomicrobiae 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 2IUTZ@203494,46VVK@74201,COG1352@1,COG1352@2 NA|NA|NA NT Methyltransferase, chemotaxis proteins JOKFNDED_01877 452637.Oter_3575 1e-54 221.9 Bacteria Bacteria COG0642@1,COG0745@1,COG0745@2,COG2203@1,COG2203@2,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_01880 756272.Plabr_1070 9.5e-176 623.2 Bacteria 3.1.1.11 ko:K01051 ko00040,ko01100,map00040,map01100 M00081 R02362 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria COG0657@1,COG0657@2,COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_01883 697282.Mettu_3625 3.1e-74 285.8 Gammaproteobacteria Bacteria 1MXKK@1224,1RSMZ@1236,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase JOKFNDED_01884 1303518.CCALI_02848 1.9e-58 232.6 Bacteria Bacteria COG5285@1,COG5285@2 NA|NA|NA Q dioxygenase activity JOKFNDED_01885 382464.ABSI01000011_gene2445 1.1e-82 313.2 Verrucomicrobiae Bacteria 2IURP@203494,46SBH@74201,COG1432@1,COG1432@2 NA|NA|NA S NYN domain JOKFNDED_01886 264462.Bd1370 5.9e-120 437.6 Bdellovibrionales 3.6.4.13 ko:K03732 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03019 Bacteria 1NUZU@1224,2MTUN@213481,2WUYJ@28221,42ZQT@68525,COG0513@1,COG0513@2 NA|NA|NA JKL helicase superfamily c-terminal domain JOKFNDED_01887 794903.OPIT5_17635 1.3e-38 166.0 Opitutae inaA ko:K02848 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 3K85W@414999,46ST7@74201,COG3642@1,COG3642@2 NA|NA|NA T lipopolysaccharide core region biosynthetic process JOKFNDED_01889 452637.Oter_1808 2.5e-29 135.6 Opitutae ko:K13572 ko00000,ko03051 Bacteria 3K846@414999,46VG3@74201,COG2378@1,COG2378@2 NA|NA|NA K WYL domain JOKFNDED_01890 32042.PstZobell_12751 3e-22 112.8 Proteobacteria Bacteria 1P7ED@1224,2DG83@1,2ZUVI@2 NA|NA|NA JOKFNDED_01892 883126.HMPREF9710_00499 3e-143 515.4 Betaproteobacteria nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 1QUUG@1224,2W0DD@28216,COG2251@1,COG2251@2 NA|NA|NA S Domain of unknown function(DUF2779) JOKFNDED_01893 304371.MCP_0983 2.3e-42 178.7 Methanomicrobia GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.1.3.48 ko:K14165 ko00000,ko01000,ko01009 Archaea 2NAVK@224756,2Y3WS@28890,COG2453@1,arCOG03413@2157 NA|NA|NA T Dual specificity phosphatase, catalytic domain JOKFNDED_01894 411901.BACCAC_01664 7.7e-59 234.2 Bacteroidaceae Bacteria 2A8DZ@1,2FXXX@200643,30XFT@2,4AU0D@815,4PAWR@976 NA|NA|NA JOKFNDED_01895 232346.JHQL01000004_gene1658 1.9e-17 95.5 Proteobacteria Bacteria 1MZRR@1224,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_01898 530564.Psta_3443 6.7e-09 67.8 Bacteria Bacteria COG2865@1,COG2865@2 NA|NA|NA JOKFNDED_01899 1090319.KE386571_gene2211 2e-18 100.9 Sphingomonadales Bacteria 1RBWH@1224,2K7U5@204457,2U6MJ@28211,COG4928@1,COG4928@2 NA|NA|NA S KAP family P-loop domain JOKFNDED_01900 1121422.AUMW01000002_gene2222 0.0 1164.1 Peptococcaceae Bacteria 1TQ5E@1239,25C98@186801,260VT@186807,COG0553@1,COG0553@2 NA|NA|NA L PFAM DNA RNA helicase, C-terminal JOKFNDED_01903 880072.Desac_1345 0.0 1293.9 Deltaproteobacteria rsmJ 2.1.1.242 ko:K15984 ko00000,ko01000,ko03009 Bacteria 1MW7U@1224,2WNXH@28221,42RFU@68525,COG1743@1,COG1743@2 NA|NA|NA L Protein of unknown function (DUF1156) JOKFNDED_01905 880072.Desac_1343 1.8e-47 196.1 Proteobacteria Bacteria 1NX5G@1224,2BM7J@1,32FR9@2 NA|NA|NA JOKFNDED_01906 1121422.AUMW01000002_gene2225 0.0 1110.1 Peptococcaceae Bacteria 1TPPM@1239,250B3@186801,266ZF@186807,COG1483@1,COG1483@2 NA|NA|NA S Protein of unknown function (DUF499) JOKFNDED_01907 1356852.N008_20935 1.6e-58 233.4 Cytophagia mcrC ko:K19147 ko00000,ko02048 Bacteria 47Q64@768503,4NPAZ@976,COG4268@1,COG4268@2 NA|NA|NA V McrBC 5-methylcytosine restriction system component JOKFNDED_01908 1121123.AUAO01000003_gene2442 3.5e-92 346.7 Alphaproteobacteria mcrB GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015666,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0017111,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901575 ko:K07452,ko:K07454 ko00000,ko01000,ko02048 Bacteria 1MYQM@1224,2TVV9@28211,COG1401@1,COG1401@2,COG3440@1,COG3440@2 NA|NA|NA V GTPase subunit of restriction endonuclease JOKFNDED_01910 877455.Metbo_1563 1.2e-27 130.6 Archaea nucS ko:K07503 ko00000,ko01000 Archaea COG0457@1,COG1637@1,arCOG01304@2157,arCOG03038@2157 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures JOKFNDED_01917 1396141.BATP01000035_gene4026 1e-25 123.6 Verrucomicrobiae yedK Bacteria 2IUZK@203494,46T39@74201,COG2135@1,COG2135@2 NA|NA|NA S SOS response associated peptidase (SRAP) JOKFNDED_01919 1283300.ATXB01000001_gene1690 8.8e-91 340.5 Gammaproteobacteria ko:K07001 ko00000 Bacteria 1MUI6@1224,1SEED@1236,COG1752@1,COG1752@2 NA|NA|NA S Patatin-like phospholipase JOKFNDED_01920 395493.BegalDRAFT_2263 5.4e-38 164.9 Thiotrichales tolC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1QEXA@1224,1TBUM@1236,463E2@72273,COG1538@1,COG1538@2,COG2885@1,COG2885@2 NA|NA|NA N PFAM Outer membrane efflux protein JOKFNDED_01921 240016.ABIZ01000001_gene1219 5.4e-140 505.0 Verrucomicrobiae secA2 ko:K03070,ko:K07039 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2ITJP@203494,46SJC@74201,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane JOKFNDED_01923 1403819.BATR01000181_gene6216 7.8e-254 882.9 Verrucomicrobiae pckG GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2638 Bacteria 2ITQG@203494,46UB8@74201,COG1274@1,COG1274@2 NA|NA|NA C Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle JOKFNDED_01924 1121430.JMLG01000033_gene1363 5.4e-41 174.9 Peptococcaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,248W2@186801,260XQ@186807,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs JOKFNDED_01925 1304885.AUEY01000096_gene2839 2.3e-128 466.5 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_01926 1123070.KB899260_gene2038 3.5e-120 438.3 Verrucomicrobiae tal GO:0003674,GO:0003824,GO:0004801,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 iYL1228.KPN_02798 Bacteria 2ITMF@203494,46UAK@74201,COG0176@1,COG0176@2 NA|NA|NA G Transaldolase/Fructose-6-phosphate aldolase JOKFNDED_01927 1396418.BATQ01000011_gene4501 4.1e-145 521.2 Verrucomicrobia Bacteria 46UGU@74201,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V JOKFNDED_01928 1403819.BATR01000018_gene599 5e-96 357.8 Verrucomicrobia Bacteria 46UIH@74201,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase JOKFNDED_01929 583355.Caka_2607 1.5e-138 499.6 Opitutae thrC GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7E5@414999,46TPG@74201,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase JOKFNDED_01930 1396141.BATP01000003_gene5096 1.5e-173 616.3 Verrucomicrobiae 3.2.1.8 ko:K01181 ko00000,ko01000 Bacteria 2IUEB@203494,46X3D@74201,COG3693@1,COG3693@2 NA|NA|NA G Glycosyl hydrolase family 10 JOKFNDED_01932 1396418.BATQ01000175_gene2734 3.4e-143 515.0 Verrucomicrobiae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 2ITHE@203494,46SIY@74201,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase JOKFNDED_01933 1403819.BATR01000181_gene6088 1.1e-52 213.4 Verrucomicrobiae polX ko:K02347,ko:K04477 ko00000,ko03400 Bacteria 2IVU0@203494,46VK8@74201,COG1387@1,COG1387@2 NA|NA|NA E Domain of Unknown Function (DUF1080) JOKFNDED_01936 382464.ABSI01000013_gene1931 9e-19 100.1 Bacteria ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_01938 1123070.KB899248_gene202 1e-24 120.2 Verrucomicrobiae rlpA ko:K03642 ko00000 Bacteria 2IUW1@203494,46WTP@74201,COG0797@1,COG0797@2 NA|NA|NA M Lytic transglycolase JOKFNDED_01939 1396418.BATQ01000016_gene4228 1.1e-11 77.8 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_01941 65093.PCC7418_1203 3.2e-20 105.1 Cyanobacteria Bacteria 1G8N9@1117,COG0607@1,COG0607@2 NA|NA|NA P PFAM Rhodanese-like domain JOKFNDED_01942 240016.ABIZ01000001_gene3205 7.9e-30 137.1 Verrucomicrobiae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2IUIT@203494,46TCC@74201,COG0597@1,COG0597@2 NA|NA|NA MU Signal peptidase (SPase) II JOKFNDED_01943 1123070.KB899266_gene2495 0.0 1198.0 Verrucomicrobiae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 2ITJZ@203494,46SEC@74201,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) JOKFNDED_01945 756272.Plabr_1026 2.1e-97 363.2 Bacteria Bacteria COG3011@1,COG3011@2 NA|NA|NA CH Protein conserved in bacteria JOKFNDED_01946 1403819.BATR01000164_gene5603 7.7e-150 537.7 Verrucomicrobiae mtgA GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K03693,ko:K03814,ko:K04478,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K18770,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 iAF987.Gmet_1671 Bacteria 2ITYQ@203494,46U6K@74201,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase JOKFNDED_01947 497964.CfE428DRAFT_5917 3e-229 802.0 Verrucomicrobia rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K03580 ko00000,ko01000,ko03021 Bacteria 46S56@74201,COG0553@1,COG0553@2 NA|NA|NA L RNA polymerase recycling family C-terminal JOKFNDED_01948 1227266.HMPREF1551_01142 8.3e-146 523.9 Capnocytophaga 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1ETG4@1016,1I0KJ@117743,4NKG2@976,COG2865@1,COG2865@2 NA|NA|NA K K03655 ATP-dependent DNA helicase RecG JOKFNDED_01949 1454004.AW11_00535 8.9e-138 497.3 Betaproteobacteria 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1QTZP@1224,2VKTF@28216,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 JOKFNDED_01950 382464.ABSI01000007_gene4061 2e-36 158.7 Bacteria ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria COG0848@1,COG0848@2 NA|NA|NA U biopolymer transport protein JOKFNDED_01951 1121921.KB898718_gene3440 1.1e-12 80.5 Alteromonadales genera incertae sedis ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1RH3K@1224,1S7FG@1236,2PP55@256005,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins JOKFNDED_01952 382464.ABSI01000012_gene2054 2e-48 200.3 Verrucomicrobiae Bacteria 2IVVI@203494,46TNJ@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_01953 1123070.KB899259_gene1967 9.4e-128 463.4 Verrucomicrobiae dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 Bacteria 2ITHJ@203494,46SIG@74201,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines JOKFNDED_01957 1341646.CBMO010000067_gene1152 4.7e-08 63.9 Mycobacteriaceae Bacteria 2355H@1762,2I81Y@201174,COG1335@1,COG1335@2 NA|NA|NA Q isochorismatase JOKFNDED_01958 530564.Psta_0827 6.5e-15 87.4 Planctomycetes Bacteria 2IZCR@203682,COG3861@1,COG3861@2 NA|NA|NA S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity JOKFNDED_01959 382464.ABSI01000005_gene1151 6.8e-310 1069.7 Verrucomicrobiae malP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0030978,GO:0030980,GO:0031220,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 iECNA114_1301.ECNA114_3525 Bacteria 2IV91@203494,46S5T@74201,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties JOKFNDED_01960 1396418.BATQ01000166_gene1904 1.2e-19 104.0 Verrucomicrobiae ko:K07052 ko00000 Bacteria 2IUVK@203494,46T6D@74201,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity JOKFNDED_01961 1396418.BATQ01000056_gene200 4.3e-104 384.8 Verrucomicrobiae ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 2ITY9@203494,46TKT@74201,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG4654@1,COG4654@2 NA|NA|NA CG Glucose / Sorbosone dehydrogenase JOKFNDED_01962 83219.PM02_00635 1.5e-22 113.6 Sulfitobacter Bacteria 1REJ3@1224,2U7XR@28211,3ZVG2@60136,COG2979@1,COG2979@2 NA|NA|NA S Protein of unknown function (DUF533) JOKFNDED_01963 1396418.BATQ01000027_gene5236 1e-49 203.4 Verrucomicrobiae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K22132 ko00000,ko01000,ko03009,ko03016 Bacteria 2IUB5@203494,46VH3@74201,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family JOKFNDED_01964 794903.OPIT5_07380 7.6e-65 253.8 Opitutae ko:K06890 ko00000 Bacteria 3K9GN@414999,46VEY@74201,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family JOKFNDED_01965 240016.ABIZ01000001_gene5607 7.2e-56 223.8 Verrucomicrobiae Bacteria 2IW4D@203494,46VXB@74201,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_01966 497964.CfE428DRAFT_6049 1e-122 447.2 Verrucomicrobia Bacteria 46U0A@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_01968 1403819.BATR01000005_gene138 9.1e-36 156.8 Bacteria aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria COG0703@1,COG0703@2 NA|NA|NA F shikimate kinase activity JOKFNDED_01969 1403819.BATR01000069_gene2086 9.4e-112 410.2 Verrucomicrobiae sua5 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2ITRQ@203494,46SUC@74201,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine JOKFNDED_01970 1304885.AUEY01000096_gene2839 1.1e-144 520.8 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_01972 1396141.BATP01000040_gene2077 1.5e-194 685.6 Verrucomicrobiae groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2ITQ1@203494,46S9U@74201,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions JOKFNDED_01973 1396141.BATP01000003_gene5149 4.1e-171 607.8 Verrucomicrobiae yrvN ko:K07452,ko:K07478 ko00000,ko01000,ko02048 Bacteria 2ITKR@203494,46S7H@74201,COG2256@1,COG2256@2 NA|NA|NA L MgsA AAA+ ATPase C terminal JOKFNDED_01975 1123508.JH636443_gene5047 3.7e-07 62.4 Bacteria Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein JOKFNDED_01976 497964.CfE428DRAFT_2595 8.8e-28 130.6 Verrucomicrobia cbiX Bacteria 46W9E@74201,COG2138@1,COG2138@2 NA|NA|NA S Cobalamin (vitamin B12) biosynthesis CbiX protein JOKFNDED_01977 1396141.BATP01000022_gene350 7.4e-96 357.1 Verrucomicrobiae cbiX Bacteria 2IV6F@203494,46SPE@74201,COG2138@1,COG2138@2 NA|NA|NA S CbiX JOKFNDED_01979 396588.Tgr7_0141 4.6e-155 554.3 Chromatiales ppk2 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MVE2@1224,1RM9U@1236,1WXCM@135613,COG2326@1,COG2326@2 NA|NA|NA S PFAM Polyphosphate kinase 2 JOKFNDED_01980 1396141.BATP01000034_gene4167 2.1e-24 121.3 Verrucomicrobiae ko:K09766 ko00000 Bacteria 2IW5T@203494,46WVI@74201,COG3266@1,COG3266@2,COG4625@1,COG4625@2 NA|NA|NA U Passenger-associated-transport-repeat JOKFNDED_01981 240016.ABIZ01000001_gene1124 4.6e-199 700.7 Verrucomicrobiae 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 2ITJ5@203494,46TEJ@74201,COG2873@1,COG2873@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme JOKFNDED_01982 1403819.BATR01000104_gene3557 8.8e-83 313.9 Bacteria Bacteria COG3055@1,COG3055@2 NA|NA|NA G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses JOKFNDED_01984 1403819.BATR01000005_gene168 1.6e-167 595.9 Verrucomicrobiae ko:K03294 ko00000 2.A.3.2 Bacteria 2IWAN@203494,46W3Q@74201,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease JOKFNDED_01985 227377.CBU_1820 3.8e-27 128.3 Proteobacteria Bacteria 1N9I1@1224,2BHMV@1,32BQM@2 NA|NA|NA JOKFNDED_01986 1096546.WYO_2901 4.2e-09 67.8 Methylobacteriaceae Bacteria 1JUU9@119045,1NEQW@1224,2EDZW@1,2UI4D@28211,337UQ@2 NA|NA|NA JOKFNDED_01987 1283300.ATXB01000002_gene2702 0.0 1168.3 Gammaproteobacteria ko:K03296 ko00000 2.A.6.2 Bacteria 1MU48@1224,1RMBN@1236,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family JOKFNDED_01988 765912.Thimo_1229 9.1e-52 211.1 Chromatiales mdtA_1 Bacteria 1MUFW@1224,1S2IK@1236,1WZ20@135613,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_01989 1396141.BATP01000003_gene4899 2e-72 278.9 Verrucomicrobiae ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 2ITIE@203494,46THR@74201,COG0659@1,COG0659@2 NA|NA|NA P Sulfate permease family JOKFNDED_01990 1396141.BATP01000007_gene5633 1.7e-09 67.8 Verrucomicrobia 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 46TE7@74201,COG1785@1,COG1785@2 NA|NA|NA P Alkaline phosphatase JOKFNDED_01991 1254432.SCE1572_39205 8.9e-55 220.7 Myxococcales mtfA ko:K09933 ko00000,ko01002 Bacteria 1RAHF@1224,2WUIA@28221,2YV7F@29,42QKQ@68525,COG3228@1,COG3228@2 NA|NA|NA S Belongs to the MtfA family JOKFNDED_01992 1123070.KB899253_gene1036 3.2e-223 781.2 Verrucomicrobiae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 2ITHM@203494,46SF9@74201,COG4108@1,COG4108@2 NA|NA|NA J Class II release factor RF3, C-terminal domain JOKFNDED_01993 240016.ABIZ01000001_gene1555 1.2e-66 260.4 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_01995 344747.PM8797T_10974 2.8e-159 569.7 Planctomycetes Bacteria 2IX73@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C PFAM PBS lyase HEAT domain protein JOKFNDED_01997 344747.PM8797T_18584 1.7e-134 485.7 Planctomycetes gnl GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IXZT@203682,COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase JOKFNDED_01998 1396418.BATQ01000056_gene233 5.8e-19 103.6 Bacteria ko:K09800 ko00000,ko02000 Bacteria COG2982@1,COG2982@2 NA|NA|NA M Protein involved in outer membrane biogenesis JOKFNDED_01999 756272.Plabr_0617 4.8e-112 411.8 Planctomycetes yegT ko:K03301,ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25,2.A.12 Bacteria 2IWTX@203682,COG2211@1,COG2211@2 NA|NA|NA G MFS_1 like family JOKFNDED_02001 331869.BAL199_22747 1.4e-35 155.2 unclassified Alphaproteobacteria ko:K07493 ko00000 Bacteria 1MU4P@1224,2TUQT@28211,4BPF8@82117,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain JOKFNDED_02003 1278073.MYSTI_03638 1.9e-47 197.2 Myxococcales xdhA 1.17.1.4,1.17.3.2,1.2.5.3 ko:K00106,ko:K03518,ko:K13481,ko:K13482 ko00230,ko00232,ko00983,ko01100,ko01110,ko01120,ko04146,map00230,map00232,map00983,map01100,map01110,map01120,map04146 M00546 R01768,R01769,R02103,R02107,R07942,R07977,R07978,R07979,R08235,R11168 RC00143,RC02017,RC02199,RC02800 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1NQSR@1224,2X7DZ@28221,2YWS9@29,43C3C@68525,COG4630@1,COG4630@2,COG4631@1,COG4631@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain JOKFNDED_02004 1144275.COCOR_05728 5.9e-96 359.0 Myxococcales xdhA 1.17.1.4,1.17.3.2,1.2.5.3 ko:K00106,ko:K03518,ko:K13481,ko:K13482 ko00230,ko00232,ko00983,ko01100,ko01110,ko01120,ko04146,map00230,map00232,map00983,map01100,map01110,map01120,map04146 M00546 R01768,R01769,R02103,R02107,R07942,R07977,R07978,R07979,R08235,R11168 RC00143,RC02017,RC02199,RC02800 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1NQSR@1224,2X7DZ@28221,2YWS9@29,43C3C@68525,COG4630@1,COG4630@2,COG4631@1,COG4631@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain JOKFNDED_02005 344747.PM8797T_25371 2.8e-105 389.4 Planctomycetes ko:K03455 ko00000 2.A.37 Bacteria 2J51D@203682,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family JOKFNDED_02008 240016.ABIZ01000001_gene4799 2.5e-58 232.3 Verrucomicrobiae Bacteria 2IVT5@203494,46UCJ@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_02009 530564.Psta_1258 7.9e-115 420.2 Planctomycetes dapA2 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY4I@203682,COG0329@1,COG0329@2 NA|NA|NA EM Belongs to the DapA family JOKFNDED_02010 756272.Plabr_3809 4.2e-47 194.9 Planctomycetes 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 Bacteria 2IYBV@203682,COG3485@1,COG3485@2 NA|NA|NA Q protocatechuate 3,4-dioxygenase, beta subunit JOKFNDED_02011 216591.BCAM1267 3.1e-92 345.1 Burkholderiaceae GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 ko:K01777,ko:K12658 ko00330,ko01100,map00330,map01100 R01255,R03296 RC00479 ko00000,ko00001,ko01000 Bacteria 1K4R9@119060,1NVF9@1224,2VHHY@28216,COG3938@1,COG3938@2 NA|NA|NA E Belongs to the proline racemase family JOKFNDED_02012 530564.Psta_1014 2.8e-265 921.4 Planctomycetes ptpA_1 Bacteria 2IY8M@203682,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA E Dipeptidyl peptidase IV (DPP IV) JOKFNDED_02013 497964.CfE428DRAFT_1990 5.4e-138 497.7 Verrucomicrobia dadA 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 46TXP@74201,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase JOKFNDED_02014 118166.JH976537_gene2771 3.1e-48 199.1 Oscillatoriales piv ko:K07486 ko00000 Bacteria 1G5MH@1117,1HDVG@1150,COG3547@1,COG3547@2 NA|NA|NA L Transposase IS116/IS110/IS902 family JOKFNDED_02015 497964.CfE428DRAFT_6315 3.5e-157 561.6 Verrucomicrobia Bacteria 46TDV@74201,COG3356@1,COG3356@2 NA|NA|NA S Neutral/alkaline non-lysosomal ceramidase, N-terminal JOKFNDED_02017 987059.RBXJA2T_18718 6.7e-98 364.0 unclassified Burkholderiales yihG Bacteria 1KN0M@119065,1MVWG@1224,2VI6Y@28216,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases JOKFNDED_02018 670307.HYPDE_25418 3.9e-138 498.0 Alphaproteobacteria eryK Bacteria 1MY5H@1224,2TR6X@28211,COG2124@1,COG2124@2 NA|NA|NA Q Cytochrome P450 JOKFNDED_02020 452637.Oter_4054 1.3e-72 280.8 Opitutae dinB 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 3K9GX@414999,46SR8@74201,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family JOKFNDED_02021 1396418.BATQ01000168_gene1793 0.0 1159.1 Verrucomicrobiae dnaE2 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IU0A@203494,46S6W@74201,COG0587@1,COG0587@2 NA|NA|NA L Bacterial DNA polymerase III alpha subunit JOKFNDED_02023 1396141.BATP01000005_gene6032 8.4e-08 64.3 Verrucomicrobiae Bacteria 2A70J@1,2IWEJ@203494,30VVR@2,46X10@74201 NA|NA|NA JOKFNDED_02024 395964.KE386496_gene1868 0.0 1978.8 Beijerinckiaceae nrsA ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Bacteria 1QK4F@1224,2TRUN@28211,3NAMB@45404,COG0001@1,COG0001@2,COG1020@1,COG1020@2,COG3321@1,COG3321@2 NA|NA|NA Q Acyl transferase domain in polyketide synthase (PKS) enzymes. JOKFNDED_02025 497964.CfE428DRAFT_1494 5.3e-66 257.3 Verrucomicrobia acuC Bacteria 46SMT@74201,COG0123@1,COG0123@2 NA|NA|NA BQ Histone deacetylase domain JOKFNDED_02026 1232410.KI421424_gene1717 4.7e-135 488.4 Deltaproteobacteria ndhD5 1.6.5.3 ko:K05568,ko:K05575 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2 iJN678.ndhD Bacteria 1MV6V@1224,2WIS1@28221,42MSA@68525,COG0651@1,COG0651@2 NA|NA|NA CP PFAM NADH Ubiquinone plastoquinone (complex I) JOKFNDED_02027 439235.Dalk_4925 2e-09 68.6 Desulfobacterales Bacteria 1Q4JY@1224,2EAIM@1,2MPQQ@213118,2WT7M@28221,334MN@2,42XPC@68525 NA|NA|NA JOKFNDED_02028 177437.HRM2_35350 1.7e-146 526.2 Desulfobacterales nuoL2 1.6.5.3 ko:K00341,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 Bacteria 1QU5Z@1224,2MIB7@213118,2WJ56@28221,42MDX@68525,COG0651@1,COG0651@2 NA|NA|NA CP PFAM NADH Ubiquinone plastoquinone (complex I) JOKFNDED_02029 589865.DaAHT2_2523 5.1e-117 428.3 Desulfobacterales nuoN2 ko:K05568 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1MURB@1224,2MHXG@213118,2WJ58@28221,42PD3@68525,COG0651@1,COG0651@2 NA|NA|NA CP Proton-conducting membrane transporter JOKFNDED_02030 1121459.AQXE01000005_gene1640 1.8e-30 139.0 Desulfovibrionales mnhC 1.6.5.3 ko:K00340,ko:K05567 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 Bacteria 1RGU1@1224,2MC72@213115,2WP3K@28221,42SX0@68525,COG1006@1,COG1006@2 NA|NA|NA P PFAM NADH-ubiquinone oxidoreductase chain 4L JOKFNDED_02031 177437.HRM2_35380 2.5e-56 225.7 Desulfobacterales mnhB ko:K05566 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N1CK@1224,2MK09@213118,2WNIJ@28221,42S1S@68525,COG2111@1,COG2111@2 NA|NA|NA P Domain related to MnhB subunit of Na+/H+ antiporter JOKFNDED_02032 1232410.KI421424_gene1709 1.3e-16 92.0 Deltaproteobacteria mnhB ko:K05566 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N5EN@1224,2WQK2@28221,42UDW@68525,COG1563@1,COG1563@2 NA|NA|NA P Domain of unknown function (DUF4040) JOKFNDED_02033 439235.Dalk_4919 9.4e-17 93.2 Desulfobacterales mnhG ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1QFGT@1224,2MKFZ@213118,2WRRI@28221,42W2H@68525,COG1320@1,COG1320@2 NA|NA|NA P TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit JOKFNDED_02034 589865.DaAHT2_2518 1e-18 99.4 Deltaproteobacteria mnhF ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1N6VV@1224,2X6T0@28221,43BEF@68525,COG2212@1,COG2212@2 NA|NA|NA P Multiple resistance and pH regulation protein F (MrpF / PhaF) JOKFNDED_02035 589865.DaAHT2_2517 5.3e-37 161.0 Desulfobacterales mnhE ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 1MZYJ@1224,2MKPM@213118,2WQSA@28221,42U8N@68525,COG1863@1,COG1863@2 NA|NA|NA P Na+/H+ ion antiporter subunit JOKFNDED_02036 1396418.BATQ01000027_gene5240 3.7e-17 95.9 Verrucomicrobiae Bacteria 2IUKR@203494,46X62@74201,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like JOKFNDED_02037 1005048.CFU_0527 6.6e-11 74.7 Proteobacteria Bacteria 1P9RC@1224,2ZTA6@2,COG1258@1 NA|NA|NA J pseudouridine synthase activity JOKFNDED_02039 794903.OPIT5_15135 4.4e-61 242.3 Verrucomicrobia ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 46U8P@74201,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A domain JOKFNDED_02041 1123242.JH636435_gene2487 6.4e-79 302.8 Planctomycetes Bacteria 2IXDF@203682,COG0515@1,COG0515@2,COG2319@1,COG2319@2 NA|NA|NA KLT Protein kinase domain JOKFNDED_02042 419947.MRA_1251 2.9e-27 128.3 Mycobacteriaceae GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 ko:K07064 ko00000 Bacteria 23DIH@1762,2GU0J@201174,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_02043 557599.MKAN_18030 2.1e-10 71.6 Mycobacteriaceae GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 Bacteria 23EA2@1762,2DSUP@1,2GV46@201174,33HGU@2 NA|NA|NA JOKFNDED_02044 1210884.HG799465_gene12152 2.5e-30 140.2 Planctomycetes Bacteria 2IXSY@203682,COG2319@1,COG2319@2 NA|NA|NA S Planctomycete cytochrome C JOKFNDED_02045 313628.LNTAR_22174 1.4e-08 65.1 Bacteria Bacteria COG3828@1,COG3828@2 NA|NA|NA N Trehalose utilisation JOKFNDED_02046 983917.RGE_11620 5.4e-16 90.1 unclassified Burkholderiales ccoG Bacteria 1KIYJ@119065,1MVFY@1224,2VHRH@28216,COG0348@1,COG0348@2 NA|NA|NA C cytochrome C oxidase JOKFNDED_02048 1125863.JAFN01000001_gene829 1.1e-24 121.3 Deltaproteobacteria fadL ko:K06076 ko00000,ko02000 1.B.9 Bacteria 1MUU4@1224,2WK7H@28221,42N9J@68525,COG2067@1,COG2067@2 NA|NA|NA I PFAM membrane protein involved in aromatic hydrocarbon degradation JOKFNDED_02049 395493.BegalDRAFT_0067 4.4e-46 192.6 Proteobacteria Bacteria 1QZX9@1224,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_02050 521674.Plim_1664 4.6e-91 341.3 Planctomycetes ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 2IXKS@203682,COG0583@1,COG0583@2 NA|NA|NA K Hydrogen peroxide-inducible genes activator JOKFNDED_02051 530564.Psta_2741 0.0 1165.6 Planctomycetes katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 2IY35@203682,COG0376@1,COG0376@2 NA|NA|NA P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity JOKFNDED_02052 497964.CfE428DRAFT_3642 1.4e-38 167.9 Bacteria 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria COG1262@1,COG1262@2 NA|NA|NA T PFAM Formylglycine-generating sulfatase enzyme JOKFNDED_02053 1218352.B597_020905 7.3e-97 360.9 Pseudomonas stutzeri group Bacteria 1P11B@1224,1RYWN@1236,1Z4AS@136846,COG4924@1,COG4924@2 NA|NA|NA S Uncharacterized protein conserved in bacteria N-term (DUF3322) JOKFNDED_02054 1254432.SCE1572_50385 8.7e-18 97.1 Deltaproteobacteria Bacteria 1NCV2@1224,2DS36@1,2WR78@28221,32US8@2,42WR2@68525 NA|NA|NA JOKFNDED_02055 1173028.ANKO01000112_gene4912 4.8e-92 345.1 Oscillatoriales Bacteria 1G2C3@1117,1H95K@1150,COG4938@1,COG4938@2 NA|NA|NA S Protein of unknown function (DUF3696) JOKFNDED_02056 1046724.KB889930_gene1319 1.4e-278 966.1 Gammaproteobacteria Bacteria 1N16Z@1224,1RPTX@1236,COG4913@1,COG4913@2 NA|NA|NA S protein conserved in bacteria JOKFNDED_02057 1500257.JQNM01000002_gene4366 1.4e-18 99.4 Rhizobiaceae Bacteria 1RJ2J@1224,2UA97@28211,4BEJ5@82115,COG1487@1,COG1487@2 NA|NA|NA S PIN domain JOKFNDED_02059 498211.CJA_1586 3.5e-40 171.4 Gammaproteobacteria Bacteria 1R6H1@1224,1S0T7@1236,28N0W@1,2ZB75@2 NA|NA|NA S Domain of unknown function (DUF4194) JOKFNDED_02060 1123070.KB899252_gene965 4.6e-108 397.9 Verrucomicrobiae rng 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2ITMW@203494,46S5S@74201,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E/G family JOKFNDED_02061 497964.CfE428DRAFT_1557 6e-32 144.8 Verrucomicrobia Bacteria 2F9IJ@1,341UX@2,46VNE@74201 NA|NA|NA JOKFNDED_02062 1157490.EL26_13075 3e-81 308.1 Alicyclobacillaceae sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009408,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010269,GO:0010447,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030145,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071291,GO:0071450,GO:0071451,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_4213,iECSF_1327.ECSF_3769 Bacteria 1TPXT@1239,2781X@186823,4HA6U@91061,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems JOKFNDED_02063 794903.OPIT5_13510 5.1e-169 600.5 Opitutae nrdB 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iJN746.PP_1177 Bacteria 3K7VI@414999,46SMW@74201,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides JOKFNDED_02065 240016.ABIZ01000001_gene1555 1.3e-31 143.3 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_02066 1403819.BATR01000002_gene75 3.1e-60 239.2 Verrucomicrobiae 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2IU54@203494,46SZY@74201,COG1686@1,COG1686@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase JOKFNDED_02067 240016.ABIZ01000001_gene363 4.5e-131 475.7 Verrucomicrobiae Bacteria 2IWP7@203494,46Z3U@74201,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain JOKFNDED_02070 1396141.BATP01000001_gene5305 1.7e-59 236.1 Bacteria rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0222@1,COG0222@2 NA|NA|NA J mitochondrial gene expression JOKFNDED_02071 1396141.BATP01000030_gene3701 6.3e-50 204.1 Verrucomicrobiae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2IU9Q@203494,46SQG@74201,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase homologues. JOKFNDED_02072 240016.ABIZ01000001_gene2279 1.9e-66 258.8 Verrucomicrobiae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUB8@203494,46SPU@74201,COG0452@1,COG0452@2 NA|NA|NA H Flavoprotein JOKFNDED_02073 1396141.BATP01000040_gene2109 4e-57 228.0 Verrucomicrobiae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU6G@203494,46WUX@74201,COG0452@1,COG0452@2 NA|NA|NA H DNA / pantothenate metabolism flavoprotein JOKFNDED_02074 215803.DB30_6451 1.3e-237 829.7 Myxococcales 1.6.5.8 ko:K00347,ko:K03614,ko:K21163 ko01059,ko01130,map01059,map01130 M00824 ko00000,ko00001,ko00002,ko01000 Bacteria 1QX8H@1224,2X7C7@28221,2YXH2@29,43C1J@68525,COG4658@1,COG4658@2 NA|NA|NA C ASPIC and UnbV JOKFNDED_02075 1120980.JQKH01000081_gene858 7.9e-79 300.8 Neisseriales pobA Bacteria 1MX47@1224,2KSAJ@206351,2WFHC@28216,COG4638@1,COG4638@2 NA|NA|NA P Rieske [2Fe-2S] domain JOKFNDED_02076 215803.DB30_6449 2.6e-13 82.4 Myxococcales Bacteria 1P8WG@1224,28RWT@1,2X3G5@28221,2YVYF@29,2ZE8Z@2,4386A@68525 NA|NA|NA JOKFNDED_02077 56110.Oscil6304_4866 2.6e-42 179.1 Oscillatoriales Bacteria 1G3XJ@1117,1HA4M@1150,2DBEV@1,2Z8UT@2 NA|NA|NA JOKFNDED_02078 497964.CfE428DRAFT_1241 1.5e-76 293.9 Bacteria Bacteria COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase JOKFNDED_02079 1120980.JQKH01000081_gene857 2.9e-31 142.9 Betaproteobacteria Bacteria 1RBC8@1224,2BZ6D@1,2W4E7@28216,2ZC6J@2 NA|NA|NA JOKFNDED_02080 1254432.SCE1572_26715 4.6e-34 151.8 Myxococcales Bacteria 1R8YH@1224,2X3ER@28221,2YVR4@29,4384P@68525,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase JOKFNDED_02081 497964.CfE428DRAFT_1236 2.6e-40 172.6 Bacteria Bacteria 2DDJA@1,2ZIAT@2 NA|NA|NA S P-aminobenzoate N-oxygenase AurF JOKFNDED_02082 497964.CfE428DRAFT_1235 1.6e-86 326.2 Bacteria desA Bacteria COG3239@1,COG3239@2 NA|NA|NA I unsaturated fatty acid biosynthetic process JOKFNDED_02083 56107.Cylst_2011 2.5e-27 129.0 Nostocales Bacteria 1G216@1117,1HN1V@1161,COG0110@1,COG0110@2 NA|NA|NA S PFAM Bacterial transferase hexapeptide (three repeats) JOKFNDED_02084 1124991.MU9_2785 5.2e-11 74.7 Gammaproteobacteria Bacteria 1RBU6@1224,1S33C@1236,COG4319@1,COG4319@2 NA|NA|NA S ketosteroid isomerase JOKFNDED_02086 240016.ABIZ01000001_gene2045 1.9e-131 476.5 Verrucomicrobiae Bacteria 2IVEK@203494,46S5V@74201,COG0628@1,COG0628@2 NA|NA|NA T AI-2E family transporter JOKFNDED_02087 1396141.BATP01000056_gene3301 4.4e-35 155.6 Verrucomicrobiae Bacteria 2IWGR@203494,46XSD@74201,COG2885@1,COG2885@2 NA|NA|NA M OmpA family JOKFNDED_02088 1403819.BATR01000137_gene4878 1.1e-93 350.5 Verrucomicrobiae Bacteria 2IUAU@203494,46S5E@74201,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily JOKFNDED_02090 1237149.C900_02824 1.1e-58 233.8 Cytophagia ko:K07459 ko00000 Bacteria 47P95@768503,4NJ5H@976,COG4637@1,COG4637@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system JOKFNDED_02091 314230.DSM3645_10447 4e-166 592.0 Planctomycetes Bacteria 2IY00@203682,COG1020@1,COG1020@2 NA|NA|NA Q Protein of unknown function (DUF1587) JOKFNDED_02092 314230.DSM3645_10452 4.9e-139 501.1 Planctomycetes Bacteria 2IYIC@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_02093 349521.HCH_03632 1.1e-139 503.1 Gammaproteobacteria ko:K07090 ko00000 Bacteria 1QRFH@1224,1RRFY@1236,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein JOKFNDED_02094 497964.CfE428DRAFT_5675 5.6e-97 360.9 Verrucomicrobia alsR Bacteria 46TQR@74201,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain JOKFNDED_02095 382464.ABSI01000011_gene2816 3.4e-72 278.9 Verrucomicrobia Bacteria 46UDG@74201,COG4888@1,COG4888@2 NA|NA|NA O PFAM ASPIC UnbV domain protein JOKFNDED_02096 1396141.BATP01000005_gene6065 1.4e-226 792.7 Verrucomicrobiae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 ko:K01972,ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378,R00382 RC00005,RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2ITPR@203494,46TMK@74201,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA JOKFNDED_02097 1403819.BATR01000191_gene6556 1.2e-25 122.5 Verrucomicrobiae Bacteria 2DTD6@1,2IUPR@203494,33JTS@2,46WA4@74201 NA|NA|NA S CopG antitoxin of type II toxin-antitoxin system JOKFNDED_02098 497964.CfE428DRAFT_6147 7e-30 136.3 Verrucomicrobia Bacteria 2FCWX@1,344ZT@2,46WDE@74201 NA|NA|NA S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system JOKFNDED_02099 296591.Bpro_2805 1.6e-126 459.5 Comamonadaceae fdhA1 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 Bacteria 1QTZB@1224,2VP2Q@28216,4AAQA@80864,COG3383@1,COG3383@2 NA|NA|NA C formate dehydrogenase, alpha subunit JOKFNDED_02101 1396418.BATQ01000058_gene141 1.3e-38 166.0 Verrucomicrobiae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUE6@203494,46SSX@74201,COG0200@1,COG0200@2 NA|NA|NA J Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A JOKFNDED_02102 1396418.BATQ01000058_gene140 1.8e-52 212.6 Verrucomicrobiae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUC7@203494,46SUR@74201,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body JOKFNDED_02103 1396141.BATP01000039_gene1415 2.5e-32 144.8 Verrucomicrobiae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUJF@203494,46T7Z@74201,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance JOKFNDED_02104 1396418.BATQ01000058_gene138 3.9e-61 241.1 Verrucomicrobiae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IU69@203494,46SP9@74201,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center JOKFNDED_02105 1396418.BATQ01000058_gene137 1.6e-40 172.2 Verrucomicrobiae rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUCT@203494,46T2K@74201,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit JOKFNDED_02106 349741.Amuc_0926 1e-56 226.5 Verrucomicrobiae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2ITU8@203494,46SP7@74201,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits JOKFNDED_02107 497964.CfE428DRAFT_0498 2.1e-22 111.3 Verrucomicrobia rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 46T3M@74201,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit JOKFNDED_02108 349741.Amuc_0293 6.8e-49 199.9 Verrucomicrobiae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUB7@203494,46VID@74201,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome JOKFNDED_02109 349741.Amuc_0294 2.9e-25 120.9 Verrucomicrobiae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUPS@203494,46T6M@74201,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA JOKFNDED_02110 497964.CfE428DRAFT_0495 4.2e-08 63.5 Verrucomicrobia rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 46TAV@74201,COG0255@1,COG0255@2 NA|NA|NA J Ribosomal L29 protein JOKFNDED_02111 1396141.BATP01000039_gene1407 1.2e-57 229.2 Verrucomicrobiae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUCE@203494,46ST6@74201,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs JOKFNDED_02112 1403819.BATR01000164_gene5568 2.1e-86 325.5 Verrucomicrobiae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2ITPJ@203494,46SN9@74201,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation JOKFNDED_02113 1123070.KB899256_gene2222 6.9e-37 161.0 Verrucomicrobiae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUMZ@203494,46T5F@74201,COG0091@1,COG0091@2 NA|NA|NA J its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome JOKFNDED_02114 1396418.BATQ01000058_gene128 2.3e-17 96.3 Verrucomicrobiae Bacteria 2FI21@1,2IUIJ@203494,349UX@2,46W3I@74201 NA|NA|NA JOKFNDED_02115 1396418.BATQ01000058_gene127 1.3e-31 142.1 Verrucomicrobiae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUPZ@203494,46T4G@74201,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA JOKFNDED_02116 1403819.BATR01000164_gene5572 1.8e-78 298.9 Verrucomicrobiae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2ITK3@203494,46S71@74201,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity JOKFNDED_02117 497964.CfE428DRAFT_3191 9e-98 363.6 Verrucomicrobia Bacteria 46UIX@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1587) JOKFNDED_02118 497964.CfE428DRAFT_6122 8.7e-179 633.3 Verrucomicrobia Bacteria 46U03@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_02119 1396418.BATQ01000130_gene4857 4.3e-196 690.6 Verrucomicrobiae dapL GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2ITKU@203494,46TMR@74201,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II JOKFNDED_02120 1318628.MARLIPOL_07524 1.7e-25 121.7 Alteromonadaceae 2.3.1.15 ko:K08591,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1N6X6@1224,1SDQ0@1236,4685U@72275,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module JOKFNDED_02121 1328313.DS2_06411 5.2e-27 126.7 Alteromonadaceae yoeB ko:K19158 ko00000,ko01000,ko02048 Bacteria 1MZBP@1224,1S99Z@1236,467YH@72275,COG4115@1,COG4115@2 NA|NA|NA S protein conserved in bacteria JOKFNDED_02122 880071.Fleli_3670 7.2e-92 344.0 Cytophagia yhcX ko:K11206 ko00000,ko01000 Bacteria 47KHI@768503,4NEAQ@976,COG0388@1,COG0388@2 NA|NA|NA S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase JOKFNDED_02123 497964.CfE428DRAFT_3884 3.8e-77 294.3 Verrucomicrobia nuoB 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 46SMM@74201,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient JOKFNDED_02124 1396418.BATQ01000167_gene1768 7.8e-60 236.9 Verrucomicrobiae nuoC 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IU60@203494,46STM@74201,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient JOKFNDED_02125 525897.Dbac_1493 8.4e-25 120.2 Deltaproteobacteria Bacteria 1N8VN@1224,2E4SV@1,2WS4C@28221,32ZM7@2,42VKR@68525 NA|NA|NA JOKFNDED_02126 314230.DSM3645_15885 4e-120 438.0 Planctomycetes 1.1.1.2,1.1.1.307 ko:K00002,ko:K17743 ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220 M00014 R00746,R01041,R01431,R01481,R05231,R09477 RC00087,RC00088,RC00099,RC00108,RC00133 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IWVI@203682,COG0656@1,COG0656@2 NA|NA|NA S PFAM Aldo keto reductase family JOKFNDED_02127 1396141.BATP01000001_gene5388 3.8e-22 111.3 Verrucomicrobia Bacteria 3171K@2,46WQS@74201,COG1226@1 NA|NA|NA P Ion channel JOKFNDED_02128 1288963.ADIS_2102 1e-37 164.1 Cytophagia Bacteria 47MG0@768503,4NFES@976,COG4886@1,COG4886@2 NA|NA|NA S Planctomycete cytochrome C JOKFNDED_02129 344747.PM8797T_09159 1.8e-147 529.3 Planctomycetes Bacteria 2IY1W@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_02130 344747.PM8797T_08329 3.6e-186 658.7 Planctomycetes Bacteria 2J1RW@203682,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_02131 404589.Anae109_4317 1.2e-09 70.5 Proteobacteria Bacteria 1NT3X@1224,2EZ5W@1,33SBY@2 NA|NA|NA JOKFNDED_02132 1396418.BATQ01000063_gene1607 3.6e-106 392.9 Verrucomicrobiae Bacteria 2ITS0@203494,46TX9@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase JOKFNDED_02133 240016.ABIZ01000001_gene4007 2.5e-156 558.9 Verrucomicrobiae clpX2 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2IVDM@203494,46U7E@74201,COG1219@1,COG1219@2 NA|NA|NA O AAA domain (Cdc48 subfamily) JOKFNDED_02134 452637.Oter_1247 5.9e-14 83.6 Opitutae GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 Bacteria 3K8HF@414999,46XWT@74201,COG4118@1,COG4118@2 NA|NA|NA D positive regulation of growth JOKFNDED_02135 452637.Oter_1248 1.1e-35 156.4 Opitutae vapC ko:K07064 ko00000 Bacteria 3K8HY@414999,46XWY@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_02136 497964.CfE428DRAFT_0775 4.1e-92 344.7 Bacteria Bacteria COG1721@1,COG1721@2 NA|NA|NA E protein (some members contain a von Willebrand factor type A (vWA) domain JOKFNDED_02137 1403819.BATR01000092_gene2712 7.1e-131 473.8 Verrucomicrobiae ko:K03924 ko00000,ko01000 Bacteria 2ITSU@203494,46TCY@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_02138 314278.NB231_13711 1.1e-105 390.2 Gammaproteobacteria ko:K07133 ko00000 Bacteria 1RAB0@1224,1SA91@1236,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) JOKFNDED_02139 935848.JAEN01000039_gene1780 9.5e-105 387.1 Paracoccus ko:K07133 ko00000 Bacteria 1MWBT@1224,2PVEN@265,2U050@28211,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) JOKFNDED_02140 1142394.PSMK_27520 2.2e-66 259.6 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG1262@1,COG1262@2 NA|NA|NA T PFAM Formylglycine-generating sulfatase enzyme JOKFNDED_02143 595460.RRSWK_03568 2.8e-81 308.9 Planctomycetes Bacteria 2IWVC@203682,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_02144 1403819.BATR01000130_gene4640 1.1e-21 110.5 Verrucomicrobia Bacteria 46W7V@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_02145 1396418.BATQ01000106_gene5332 3.9e-26 125.9 Verrucomicrobiae Bacteria 2IUFN@203494,46SZM@74201,COG0457@1,COG0457@2 NA|NA|NA S Oxygen tolerance JOKFNDED_02146 1396418.BATQ01000015_gene4324 2.2e-22 114.0 Verrucomicrobiae exoQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02847,ko:K13009,ko:K16567,ko:K18814 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.1,9.B.67.4,9.B.67.5 Bacteria 2IW62@203494,46TC1@74201,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase JOKFNDED_02147 497964.CfE428DRAFT_2568 3.4e-79 302.0 Verrucomicrobia Bacteria 46UIR@74201,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain JOKFNDED_02148 1396418.BATQ01000145_gene3539 6.4e-63 248.1 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_02149 1396418.BATQ01000178_gene2841 2.7e-42 179.5 Bacteria ko:K19295 ko00000 Bacteria 2C7PP@1,32R7G@2 NA|NA|NA S SGNH hydrolase-like domain, acetyltransferase AlgX JOKFNDED_02150 243090.RB344 5.3e-239 833.9 Planctomycetes Bacteria 2IWSD@203682,COG0654@1,COG0654@2 NA|NA|NA CH xanthan lyase JOKFNDED_02152 314230.DSM3645_24215 2e-74 287.7 Planctomycetes Bacteria 2IXQP@203682,COG2319@1,COG2319@2 NA|NA|NA M WD-40 repeat JOKFNDED_02153 344747.PM8797T_15401 2.5e-121 443.4 Planctomycetes Bacteria 2IX64@203682,COG3064@1,COG3064@2 NA|NA|NA M Membrane JOKFNDED_02154 344747.PM8797T_15396 1.1e-190 673.3 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IXPF@203682,COG5492@1,COG5492@2 NA|NA|NA N Protein of unknown function (DUF1549) JOKFNDED_02156 1123508.JH636443_gene4618 1.6e-46 192.6 Planctomycetes Bacteria 2J08M@203682,COG3832@1,COG3832@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport JOKFNDED_02157 1538295.JY96_21090 2.8e-29 135.2 unclassified Burkholderiales gstF 2.5.1.18 ko:K00799,ko:K04750 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1KNSY@119065,1MZ7K@1224,2VTMF@28216,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein JOKFNDED_02158 1123020.AUIE01000008_gene3686 6.8e-32 143.3 Pseudomonas aeruginosa group Bacteria 1N7IY@1224,1S25M@1236,1YG0F@136841,COG3865@1,COG3865@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase JOKFNDED_02159 311403.Arad_3303 1.4e-54 219.2 Rhizobiaceae Bacteria 1RD0P@1224,2U79U@28211,4B804@82115,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase JOKFNDED_02160 228410.NE0971 7.2e-34 150.2 Nitrosomonadales phnB ko:K04750 ko00000 Bacteria 1N0S4@1224,2VU64@28216,3738I@32003,COG2764@1,COG2764@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase JOKFNDED_02161 1297570.MESS4_830023 4.6e-29 134.0 Phyllobacteriaceae ybaA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1RHC1@1224,2UC7A@28211,43KE3@69277,COG5507@1,COG5507@2 NA|NA|NA S Protein of unknown function (DUF1428) JOKFNDED_02162 1396141.BATP01000051_gene3336 5.9e-19 100.5 Verrucomicrobiae Bacteria 2DMEF@1,2IWHC@203494,32QYK@2,46W6R@74201 NA|NA|NA JOKFNDED_02163 1144319.PMI16_02808 2.8e-21 108.6 Proteobacteria Bacteria 1NBW5@1224,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein JOKFNDED_02164 1297742.A176_05794 1.7e-47 196.1 Myxococcales ko:K16137 ko00000,ko03000 Bacteria 1RA4T@1224,2WQV6@28221,2YVNN@29,42U5I@68525,COG1309@1,COG1309@2 NA|NA|NA K Bacterial transcriptional repressor C-terminal JOKFNDED_02165 240016.ABIZ01000001_gene4596 2e-58 232.6 Verrucomicrobiae lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2ITXD@203494,46SD4@74201,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell JOKFNDED_02166 1396141.BATP01000039_gene1300 2.1e-177 628.6 Verrucomicrobiae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 iEcDH1_1363.fabZ,iJN678.fabZ Bacteria 2ITYH@203494,46SG1@74201,COG0764@1,COG0764@2,COG0774@1,COG0774@2 NA|NA|NA IM Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis JOKFNDED_02168 1396141.BATP01000022_gene401 1e-78 300.8 Verrucomicrobiae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 2ITGE@203494,46SJZ@74201,COG0544@1,COG0544@2 NA|NA|NA O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase JOKFNDED_02169 314230.DSM3645_09142 2.6e-70 271.9 Planctomycetes clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2IXQN@203682,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins JOKFNDED_02171 1403819.BATR01000093_gene2915 5.6e-70 270.8 Verrucomicrobia Bacteria 46W6B@74201,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA JOKFNDED_02172 452637.Oter_2920 3.7e-108 398.3 Opitutae MA20_28770 Bacteria 3K9AX@414999,46SCD@74201,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthetase family JOKFNDED_02173 240016.ABIZ01000001_gene123 2.5e-64 253.4 Bacteria Bacteria COG1075@1,COG1075@2 NA|NA|NA KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold JOKFNDED_02175 1403819.BATR01000137_gene4890 8.3e-40 170.6 Verrucomicrobiae ko:K07025 ko00000 Bacteria 2IUUA@203494,46T57@74201,COG1011@1,COG1011@2 NA|NA|NA S HAD-hyrolase-like JOKFNDED_02176 497964.CfE428DRAFT_1789 5.6e-149 534.3 Verrucomicrobia nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 46TRP@74201,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination JOKFNDED_02177 240016.ABIZ01000001_gene3375 3.2e-215 755.0 Verrucomicrobiae infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2ITNN@203494,46S8V@74201,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex JOKFNDED_02181 240016.ABIZ01000001_gene2795 6.6e-36 157.1 Verrucomicrobiae nudH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 ko:K08311 ko03018,map03018 R10816 RC00002 ko00000,ko00001,ko01000,ko03019 Bacteria 2IUIE@203494,46VUY@74201,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain JOKFNDED_02182 497964.CfE428DRAFT_5650 1.3e-08 66.6 Verrucomicrobia Bacteria 2EGRU@1,33AI0@2,46WFI@74201 NA|NA|NA JOKFNDED_02183 1123070.KB899249_gene426 3.5e-97 361.7 Verrucomicrobiae Bacteria 2IW6H@203494,46XM9@74201,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane JOKFNDED_02184 314230.DSM3645_22424 2.7e-90 338.6 Bacteria Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_02185 1304885.AUEY01000019_gene1175 1.4e-37 164.1 Desulfobacterales 5.2.1.8 ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 1MZDK@1224,2MNB1@213118,2WNJW@28221,42RVN@68525,COG0760@1,COG0760@2 NA|NA|NA M peptidylprolyl isomerase JOKFNDED_02186 1396141.BATP01000004_gene5893 2.2e-46 191.8 Verrucomicrobiae yjbQ Bacteria 2IUFK@203494,46V31@74201,COG0432@1,COG0432@2 NA|NA|NA S Uncharacterised protein family UPF0047 JOKFNDED_02187 1396418.BATQ01000078_gene604 1.5e-84 320.5 Verrucomicrobia Bacteria 46UNX@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_02188 1123070.KB899250_gene504 1.2e-65 257.3 Verrucomicrobiae ko:K11744 ko00000 Bacteria 2IU6H@203494,46U8S@74201,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter JOKFNDED_02190 1267535.KB906767_gene4236 1.4e-41 176.8 Bacteria Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase JOKFNDED_02191 933262.AXAM01000014_gene284 3e-19 101.7 Desulfobacterales yocH ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1NUBZ@1224,2MNAS@213118,2WUSM@28221,42ZKS@68525,COG3584@1,COG3584@2 NA|NA|NA S 3D domain JOKFNDED_02192 886293.Sinac_2443 2.1e-96 360.5 Bacteria Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_02193 497964.CfE428DRAFT_3445 1.5e-37 163.7 Verrucomicrobia 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 46VIM@74201,COG2114@1,COG2114@2 NA|NA|NA T Pfam Adenylate and Guanylate cyclase catalytic domain JOKFNDED_02194 1054860.KB913030_gene5628 2.2e-40 173.3 Actinobacteria Bacteria 2GN18@201174,COG5640@1,COG5640@2 NA|NA|NA O PFAM peptidase S1 and S6, chymotrypsin Hap JOKFNDED_02195 1192124.LIG30_4830 1.4e-36 161.0 Burkholderiaceae Bacteria 1K3TX@119060,1R84F@1224,2VN09@28216,COG2327@1,COG2327@2 NA|NA|NA S Polysaccharide pyruvyl transferase JOKFNDED_02197 349741.Amuc_1234 2e-47 195.3 Verrucomicrobiae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUBQ@203494,46VEU@74201,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly JOKFNDED_02198 1123070.KB899248_gene135 7e-36 156.8 Verrucomicrobiae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUDJ@203494,46SXI@74201,COG0103@1,COG0103@2 NA|NA|NA J Ribosomal protein S9/S16 JOKFNDED_02199 1403819.BATR01000162_gene5405 1.4e-51 209.9 Verrucomicrobiae phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 ko:K02039 ko00000 Bacteria 2IUGT@203494,46SUX@74201,COG0704@1,COG0704@2 NA|NA|NA P PhoU domain JOKFNDED_02200 583355.Caka_2827 2.9e-90 338.6 Opitutae lpxH_2 Bacteria 3K7GU@414999,46U19@74201,COG2908@1,COG2908@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain JOKFNDED_02201 583355.Caka_1885 2e-94 352.8 Opitutae Bacteria 3K76E@414999,46UFK@74201,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase JOKFNDED_02202 344747.PM8797T_21998 2.6e-97 362.5 Planctomycetes gntP ko:K03299 ko00000,ko02000 2.A.8 Bacteria 2IXVP@203682,COG2610@1,COG2610@2 NA|NA|NA EG COG2610 H gluconate symporter and related JOKFNDED_02203 177439.DP1520 2.4e-54 222.2 Desulfobacterales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1MXIP@1224,2MNJ9@213118,2WQ54@28221,42TFA@68525,COG3210@1,COG3210@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_02204 177439.DPPB56 1.3e-58 236.5 Desulfobacterales Bacteria 1MXIP@1224,2MNJ9@213118,2WQ54@28221,42TFA@68525,COG3210@1,COG3210@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_02205 349741.Amuc_0047 7.5e-65 253.8 Verrucomicrobiae menG 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU7J@203494,46STX@74201,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family JOKFNDED_02207 349741.Amuc_1526 7.5e-31 141.0 Verrucomicrobiae lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 2IUII@203494,46T01@74201,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family JOKFNDED_02208 357808.RoseRS_4213 5.8e-36 158.3 Chloroflexia terC ko:K05794 ko00000 Bacteria 2GASE@200795,37757@32061,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family JOKFNDED_02209 640081.Dsui_0423 3.2e-81 308.9 Rhodocyclales ydiK GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1MVX7@1224,2KW9W@206389,2VIIX@28216,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter JOKFNDED_02210 1268237.G114_09189 7e-107 394.0 Aeromonadales yrbG ko:K07301 ko00000,ko02000 2.A.19.5 Bacteria 1MU3R@1224,1RMRD@1236,1Y40H@135624,COG0530@1,COG0530@2 NA|NA|NA P COG0530 Ca2 Na antiporter JOKFNDED_02211 382464.ABSI01000021_gene445 3.4e-203 714.9 Verrucomicrobiae cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K06200 ko00000 Bacteria 2IU78@203494,46SC3@74201,COG1966@1,COG1966@2 NA|NA|NA T 5TM C-terminal transporter carbon starvation CstA JOKFNDED_02212 1396141.BATP01000058_gene2004 2.5e-23 115.2 Bacteria Bacteria 28U1Y@1,2ZG85@2 NA|NA|NA JOKFNDED_02213 313628.LNTAR_15662 5e-22 110.9 Bacteria Bacteria COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity JOKFNDED_02214 864073.HFRIS_015791 2.7e-11 75.1 Bacteria Bacteria 28ZKX@1,2ZMC7@2 NA|NA|NA S Protein of unknown function (DUF3997) JOKFNDED_02216 497964.CfE428DRAFT_3030 6.9e-81 307.4 Verrucomicrobia folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 46SSW@74201,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives JOKFNDED_02217 243090.RB3601 4.5e-21 108.6 Bacteria 4.2.2.3 ko:K01729 ko00051,map00051 R03706 ko00000,ko00001,ko01000 Bacteria COG3291@1,COG3291@2 NA|NA|NA S metallopeptidase activity JOKFNDED_02220 497964.CfE428DRAFT_4067 2.4e-87 328.9 Verrucomicrobia glxR 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 R01745,R01747 RC00099 ko00000,ko00001,ko01000 Bacteria 46VRR@74201,COG2084@1,COG2084@2 NA|NA|NA I Shikimate / quinate 5-dehydrogenase JOKFNDED_02221 497964.CfE428DRAFT_5415 2.3e-107 395.6 Bacteria MA20_27225 1.1.1.410,4.2.1.45 ko:K01709,ko:K22025 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria COG0451@1,COG0451@2 NA|NA|NA GM ADP-glyceromanno-heptose 6-epimerase activity JOKFNDED_02223 706191.PANA_1178 7.4e-16 90.9 Gammaproteobacteria Bacteria 1NSCY@1224,1SJZF@1236,2EYAQ@1,33RJ4@2 NA|NA|NA S to alpha proteobacterium BAL199, malate dehydrogenase (NCBI ZP_02186284.1) JOKFNDED_02224 1123070.KB899251_gene716 4e-159 567.8 Verrucomicrobiae sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2261,iYO844.BSU16090 Bacteria 2ITNQ@203494,46TDG@74201,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit JOKFNDED_02225 240016.ABIZ01000001_gene1473 6e-53 215.3 Verrucomicrobiae ko:K03640 ko00000,ko02000 2.C.1.2 Bacteria 2IU9R@203494,46ZBB@74201,COG2885@1,COG2885@2 NA|NA|NA M OmpA family JOKFNDED_02226 1403819.BATR01000133_gene4732 3.1e-24 118.2 Verrucomicrobiae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IU07@203494,46S7Y@74201,COG0124@1,COG0124@2 NA|NA|NA J Histidyl-tRNA synthetase JOKFNDED_02228 682795.AciX8_4363 3.1e-41 174.5 Acidobacteriia ko:K09966 ko00000 Bacteria 2JMVI@204432,3Y7NH@57723,COG3651@1,COG3651@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2237) JOKFNDED_02229 1403819.BATR01000051_gene1483 2.4e-42 179.1 Verrucomicrobiae yceH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K03810,ko:K09915 ko00000 Bacteria 2IVZN@203494,46VIH@74201,COG3132@1,COG3132@2 NA|NA|NA S Protein of unknown function, DUF480 JOKFNDED_02231 1123070.KB899257_gene2328 9e-166 590.1 Verrucomicrobiae glcD 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 Bacteria 2ITGW@203494,46SFA@74201,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain JOKFNDED_02232 1121097.JCM15093_3046 2.6e-19 101.7 Bacteroidaceae dgkA 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2FSJ8@200643,4AQWN@815,4NQ39@976,COG0818@1,COG0818@2 NA|NA|NA M Psort location CytoplasmicMembrane, score JOKFNDED_02233 1403819.BATR01000126_gene4503 1.8e-104 386.0 Verrucomicrobiae 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 R05066 RC00099 ko00000,ko00001,ko01000 Bacteria 2ITS6@203494,46S95@74201,COG2084@1,COG2084@2 NA|NA|NA I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase JOKFNDED_02234 713587.THITH_08300 9.2e-24 116.7 Gammaproteobacteria Bacteria 1N1KS@1224,1S9PF@1236,COG4636@1,COG4636@2 NA|NA|NA S protein conserved in cyanobacteria JOKFNDED_02235 1415780.JPOG01000001_gene2474 4.1e-117 428.7 Xanthomonadales fecA ko:K16091 ko00000,ko02000 1.B.14.1.14 Bacteria 1MWDG@1224,1RQA5@1236,1X5QP@135614,COG4772@1,COG4772@2 NA|NA|NA P receptor JOKFNDED_02236 401053.AciPR4_2583 5.9e-08 63.9 Acidobacteriia Bacteria 2EC48@1,2JJVN@204432,33633@2,3Y5ER@57723 NA|NA|NA JOKFNDED_02237 1396418.BATQ01000045_gene6067 2e-62 245.7 Verrucomicrobiae rsuA 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2IUCA@203494,46XWA@74201,COG1187@1,COG1187@2 NA|NA|NA J RNA pseudouridylate synthase JOKFNDED_02239 1396141.BATP01000019_gene1683 8.9e-197 693.3 Verrucomicrobiae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2IWEK@203494,46XR6@74201,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like JOKFNDED_02240 794903.OPIT5_05785 1.6e-24 120.2 Bacteria Bacteria 2EDTI@1,337NU@2 NA|NA|NA JOKFNDED_02241 1123057.P872_24735 7.4e-154 550.8 Cytophagia Bacteria 47N8E@768503,4NG7W@976,COG0490@1,COG0490@2,COG0569@1,COG0569@2,COG1226@1,COG1226@2 NA|NA|NA U Ion channel JOKFNDED_02242 497964.CfE428DRAFT_4431 2.8e-247 863.6 Bacteria ko:K20274 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria COG1361@1,COG1361@2,COG1520@1,COG1520@2,COG1572@1,COG1572@2,COG3227@1,COG3227@2 NA|NA|NA NU bacterial-type flagellum-dependent cell motility JOKFNDED_02243 497964.CfE428DRAFT_4564 4.6e-303 1046.6 Verrucomicrobia ppdK 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 46TNN@74201,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family JOKFNDED_02244 794903.OPIT5_15520 5.8e-61 240.7 Opitutae cysC GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 ko:K00390,ko:K00860,ko:K00958,ko:K13811 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R02021,R04928,R04929 RC00002,RC00007,RC00078,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 3K82E@414999,46V9Q@74201,COG0529@1,COG0529@2 NA|NA|NA F Catalyzes the synthesis of activated sulfate JOKFNDED_02245 314278.NB231_01823 2.4e-80 305.4 Chromatiales cysH GO:0000103,GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019379,GO:0019419,GO:0044237,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_3025,iECABU_c1320.ECABU_c30290,iECNA114_1301.ECNA114_2793,iECO103_1326.ECO103_3306,iECP_1309.ECP_2736,iECSF_1327.ECSF_2551,iETEC_1333.ETEC_2955,iLF82_1304.LF82_0415,iNRG857_1313.NRG857_13505,iSDY_1059.SDY_2964,ic_1306.c3321 Bacteria 1MXUR@1224,1RNC5@1236,1WX1T@135613,COG0175@1,COG0175@2 NA|NA|NA EH Belongs to the PAPS reductase family. CysH subfamily JOKFNDED_02246 1396141.BATP01000003_gene5116 2.5e-83 315.1 Verrucomicrobiae ahpC 1.11.1.15 ko:K03386,ko:K20011 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2ITGT@203494,46TAE@74201,COG0450@1,COG0450@2 NA|NA|NA O C-terminal domain of 1-Cys peroxiredoxin JOKFNDED_02248 1396418.BATQ01000183_gene959 1.3e-131 478.8 Verrucomicrobia Bacteria 46VI3@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_02255 445972.ANACOL_01380 4.7e-14 84.7 Ruminococcaceae Bacteria 1VAY7@1239,24JV5@186801,2E8Y4@1,3337V@2,3WPX7@541000 NA|NA|NA JOKFNDED_02260 1396141.BATP01000019_gene1715 1.3e-99 369.8 Verrucomicrobiae phoH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 2ITJX@203494,46S7S@74201,COG1702@1,COG1702@2 NA|NA|NA T PhoH-like protein JOKFNDED_02261 497964.CfE428DRAFT_6338 1e-23 116.7 Verrucomicrobia Bacteria 2FDFS@1,345HD@2,46W4Y@74201 NA|NA|NA JOKFNDED_02262 1403819.BATR01000118_gene4125 1e-50 207.2 Verrucomicrobia Bacteria 2F4CA@1,342S4@2,46VXA@74201 NA|NA|NA JOKFNDED_02263 1210884.HG799470_gene14341 8.4e-56 223.8 Planctomycetes surE 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2IZCB@203682,COG0496@1,COG0496@2 NA|NA|NA S PFAM Survival protein SurE JOKFNDED_02264 794903.OPIT5_27140 1.4e-82 313.2 Opitutae psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 3K78P@414999,46TND@74201,COG0688@1,COG0688@2 NA|NA|NA I Belongs to the phosphatidylserine decarboxylase family JOKFNDED_02266 1396141.BATP01000036_gene3824 4e-123 448.0 Verrucomicrobiae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITM6@203494,46S74@74201,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate JOKFNDED_02267 497964.CfE428DRAFT_2718 1.8e-108 399.1 Verrucomicrobia ispA GO:0003674,GO:0003824,GO:0004161,GO:0004311,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 iPC815.YPO3176,iSFV_1184.SFV_0386 Bacteria 46S62@74201,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family JOKFNDED_02268 340177.Cag_0706 3e-15 87.4 Bacteria Bacteria 2EQIX@1,33I4Y@2 NA|NA|NA JOKFNDED_02269 340177.Cag_0707 1.1e-28 132.5 Bacteria Bacteria COG3668@1,COG3668@2 NA|NA|NA D Plasmid stabilization system JOKFNDED_02270 1396141.BATP01000025_gene931 6.7e-72 277.7 Verrucomicrobiae fieF Bacteria 2IUZU@203494,46SPJ@74201,COG0053@1,COG0053@2 NA|NA|NA P Dimerisation domain of Zinc Transporter JOKFNDED_02271 1396418.BATQ01000171_gene2954 4.2e-82 311.2 Verrucomicrobiae smuG ko:K10800 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITSY@203494,46UE4@74201,COG1573@1,COG1573@2 NA|NA|NA L uracil-dna glycosylase JOKFNDED_02273 497964.CfE428DRAFT_3880 1.6e-75 289.7 Verrucomicrobia panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2643 Bacteria 46SK2@74201,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid JOKFNDED_02274 497964.CfE428DRAFT_3881 3.2e-67 261.9 Verrucomicrobia xapA GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006148,GO:0006149,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008617,GO:0009056,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009987,GO:0015949,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0022607,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0042454,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046094,GO:0046102,GO:0046115,GO:0046121,GO:0046122,GO:0046124,GO:0046128,GO:0046130,GO:0046483,GO:0046700,GO:0047724,GO:0047975,GO:0051259,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658,GO:1903227,GO:1903228 2.4.2.1 ko:K03783,ko:K03815 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 iPC815.YPO1171,iUMN146_1321.UM146_04590,iUTI89_1310.UTI89_C2739 Bacteria 46SNW@74201,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate JOKFNDED_02275 1297742.A176_00725 9.7e-159 566.6 Myxococcales shiA Bacteria 1MU46@1224,2WNT9@28221,2YYCZ@29,42QW3@68525,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter JOKFNDED_02277 1173028.ANKO01000246_gene4030 5.6e-07 60.8 Cyanobacteria Bacteria 1GABW@1117,COG1569@1,COG1569@2 NA|NA|NA S PIN domain JOKFNDED_02278 1028307.EAE_17525 3.9e-98 365.2 Enterobacter atoB 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU5G@1224,1RM93@1236,3X3R1@547,COG0183@1,COG0183@2 NA|NA|NA I Thiolase, C-terminal domain JOKFNDED_02279 56110.Oscil6304_1310 8.7e-40 170.2 Oscillatoriales Bacteria 1G5GI@1117,1HB0Z@1150,COG4636@1,COG4636@2 NA|NA|NA S InterPro IPR008538 JOKFNDED_02280 1123242.JH636434_gene4318 3.2e-169 601.7 Planctomycetes pct 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 Bacteria 2J2JK@203682,COG4670@1,COG4670@2 NA|NA|NA I Coenzyme A transferase JOKFNDED_02281 886293.Sinac_6008 1.2e-76 293.1 Planctomycetes Bacteria 2IZ8T@203682,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_02282 243090.RB5195 8.1e-165 587.0 Planctomycetes Bacteria 2J1QG@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_02283 1396418.BATQ01000136_gene3699 8.7e-128 463.8 Verrucomicrobia yndB 3.1.1.45 ko:K01061,ko:K11750 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 46UD7@74201,COG0412@1,COG0412@2,COG4409@1,COG4409@2 NA|NA|NA GQ exo-alpha-(2->6)-sialidase activity JOKFNDED_02284 1396418.BATQ01000091_gene5811 4.8e-135 487.6 Verrucomicrobiae dhsS 1.12.1.2 ko:K00436 R00700 ko00000,ko01000 iJN678.sll1559,iSB619.SA_RS08700 Bacteria 2IU5S@203494,46SCI@74201,COG0075@1,COG0075@2 NA|NA|NA E Aminotransferase class-V JOKFNDED_02285 497964.CfE428DRAFT_5734 1e-47 196.8 Verrucomicrobia trpF 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 46VS4@74201,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family JOKFNDED_02287 1178482.BJB45_14285 2.7e-25 121.7 Oceanospirillales ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1QZ7V@1224,1TI9S@1236,1XPX9@135619,COG3474@1,COG3474@2 NA|NA|NA C cytochrome JOKFNDED_02288 1279015.KB908459_gene2806 4.5e-183 647.5 Gammaproteobacteria ylaL Bacteria 1MX9E@1224,1RP2M@1236,COG2041@1,COG2041@2 NA|NA|NA C COG2041 Sulfite oxidase and related enzymes JOKFNDED_02289 497964.CfE428DRAFT_5177 1.2e-261 909.4 Verrucomicrobia ydcP ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Bacteria 46UGV@74201,COG0826@1,COG0826@2 NA|NA|NA O PFAM peptidase U32 JOKFNDED_02291 926550.CLDAP_33990 6.5e-24 117.1 Bacteria Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_02294 1120983.KB894571_gene2501 1.4e-202 712.6 Rhodobiaceae fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1JNCH@119043,1MUR8@1224,2TRMM@28211,COG2759@1,COG2759@2 NA|NA|NA F Formate--tetrahydrofolate ligase JOKFNDED_02295 497964.CfE428DRAFT_5323 1.7e-52 212.6 Verrucomicrobia rdgB 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 46SZ5@74201,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions JOKFNDED_02296 497964.CfE428DRAFT_2495 3.3e-132 478.4 Verrucomicrobia tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN746.PP_0436,iLJ478.TM0478 Bacteria 46S76@74201,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) JOKFNDED_02299 1396418.BATQ01000088_gene1029 1.3e-40 172.9 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IVXY@203494,46VNY@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_02300 240016.ABIZ01000001_gene1062 1.3e-129 469.9 Verrucomicrobia flgR ko:K02481 ko00000,ko02022 Bacteria 46SDB@74201,COG2204@1,COG2204@2 NA|NA|NA T sigma-54 factor interaction domain-containing protein JOKFNDED_02301 1123070.KB899265_gene1843 9e-68 264.2 Verrucomicrobiae rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2IU03@203494,46SUU@74201,COG0349@1,COG0349@2 NA|NA|NA J 3'-5' exonuclease JOKFNDED_02302 1396141.BATP01000025_gene896 1e-132 480.3 Verrucomicrobiae rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 2ITR1@203494,46S5Y@74201,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template JOKFNDED_02303 1123070.KB899265_gene1841 1.1e-22 113.6 Verrucomicrobiae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUJH@203494,46X3P@74201,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A JOKFNDED_02304 1396418.BATQ01000144_gene3425 1.8e-140 506.5 Verrucomicrobiae ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2ITGX@203494,46TXY@74201,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II and III secretion system protein JOKFNDED_02305 240016.ABIZ01000001_gene380 1.6e-94 354.0 Verrucomicrobia ko:K02453,ko:K10932 ko03070,ko05110,ko05111,map03070,map05110,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 46WP5@74201,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II and III secretion system protein JOKFNDED_02307 1408813.AYMG01000011_gene831 9.6e-76 289.7 Sphingobacteriia dcd 3.5.4.13,3.6.1.23 ko:K01494,ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R00568,R02100,R02325,R11896 RC00002,RC00074 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1IPNT@117747,4NFRS@976,COG0717@1,COG0717@2 NA|NA|NA F Deoxycytidine triphosphate deaminase JOKFNDED_02308 1123070.KB899248_gene161 2.2e-53 215.7 Verrucomicrobiae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 2IUAI@203494,46VD5@74201,COG0283@1,COG0283@2 NA|NA|NA F Cytidylate kinase JOKFNDED_02309 344747.PM8797T_27347 3.3e-131 474.9 Planctomycetes Bacteria 2J2MH@203682,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity JOKFNDED_02310 1396418.BATQ01000106_gene5356 5.2e-92 345.5 Verrucomicrobiae 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVVG@203494,46V2N@74201,COG2114@1,COG2114@2 NA|NA|NA T CHASE2 JOKFNDED_02311 1403819.BATR01000189_gene6455 3.7e-99 369.4 Verrucomicrobiae mrdA 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 2ITKB@203494,46TSQ@74201,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain JOKFNDED_02312 497964.CfE428DRAFT_3332 4.5e-89 335.9 Verrucomicrobia mtgA GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K03693,ko:K03814,ko:K04478,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K18770,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 iAF987.Gmet_1671 Bacteria 46TMG@74201,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase JOKFNDED_02314 1395587.P364_0103990 3.4e-51 209.1 Paenibacillaceae 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 1UV7R@1239,26U98@186822,4I6Q9@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain JOKFNDED_02315 583355.Caka_2077 1.7e-105 389.0 Opitutae tauA ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 3K8I0@414999,46U9E@74201,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like JOKFNDED_02316 583355.Caka_2075 1.6e-149 536.2 Opitutae ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 3K937@414999,46UMU@74201,COG0600@1,COG0600@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component JOKFNDED_02319 1396141.BATP01000019_gene1737 4.6e-17 94.4 Verrucomicrobiae Bacteria 2FCQS@1,2IUKT@203494,344TZ@2,46W38@74201 NA|NA|NA JOKFNDED_02320 1403819.BATR01000056_gene1744 1.2e-99 370.2 Verrucomicrobiae 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITQ4@203494,46SJS@74201,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M28 JOKFNDED_02322 240016.ABIZ01000001_gene660 5.2e-24 117.1 Verrucomicrobiae trxA ko:K03671,ko:K05838,ko:K20543 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko02000,ko03110 1.B.55.3 iIT341.HP0824 Bacteria 2IUMX@203494,46VWK@74201,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin-like domain JOKFNDED_02323 1403819.BATR01000100_gene3344 1.5e-11 76.6 Verrucomicrobia Bacteria 29NX7@1,309VB@2,46WPG@74201 NA|NA|NA JOKFNDED_02324 1403819.BATR01000051_gene1486 8.9e-234 816.6 Verrucomicrobiae prlC 3.4.24.70 ko:K01414 ko00000,ko01000,ko01002 Bacteria 2ITQT@203494,46TWS@74201,COG0339@1,COG0339@2 NA|NA|NA E Peptidase family M3 JOKFNDED_02326 240016.ABIZ01000001_gene2642 2.3e-210 738.4 Verrucomicrobiae pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2ITX8@203494,46S8K@74201,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates JOKFNDED_02327 1123070.KB899248_gene114 5.8e-79 300.8 Verrucomicrobiae kdsB 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IU4F@203494,46SS4@74201,COG1212@1,COG1212@2 NA|NA|NA M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria JOKFNDED_02328 1403819.BATR01000184_gene6349 5.8e-34 151.8 Verrucomicrobiae surA 5.2.1.8 ko:K02597,ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 2IUC6@203494,46SU4@74201,COG0760@1,COG0760@2 NA|NA|NA O SurA N-terminal domain JOKFNDED_02329 497964.CfE428DRAFT_1614 0.0 1090.1 Verrucomicrobia mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 46S6Y@74201,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site JOKFNDED_02330 478741.JAFS01000001_gene1295 2.7e-14 84.3 unclassified Verrucomicrobia Bacteria 298WE@1,2ZW0E@2,37HDN@326457,46WGQ@74201 NA|NA|NA JOKFNDED_02332 1236542.BALM01000010_gene3801 1.3e-89 337.0 Shewanellaceae mcrC ko:K19147 ko00000,ko02048 Bacteria 1MW1B@1224,1RQC0@1236,2QDDF@267890,COG4268@1,COG4268@2 NA|NA|NA V McrBC 5-methylcytosine restriction system component JOKFNDED_02333 1163409.UUA_18187 1.9e-79 303.1 Xanthomonadales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1QTS7@1224,1RN63@1236,1X375@135614,COG4096@1,COG4096@2 NA|NA|NA L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases JOKFNDED_02334 1403819.BATR01000005_gene174 1.2e-70 273.5 Verrucomicrobia 2.5.1.60 ko:K05956 ko00000,ko01000,ko01006,ko04131 Bacteria 46URI@74201,COG5029@1,COG5029@2 NA|NA|NA O Prenyltransferase and squalene oxidase repeat JOKFNDED_02336 1396418.BATQ01000067_gene1721 8.3e-135 487.3 Verrucomicrobiae pdhD 1.16.1.1,1.8.1.4 ko:K00382,ko:K00520 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITI0@203494,46S8I@74201,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain JOKFNDED_02337 1396418.BATQ01000067_gene1720 2.4e-20 105.5 Verrucomicrobiae Bacteria 2IUPK@203494,46VS6@74201,COG1664@1,COG1664@2 NA|NA|NA M Polymer-forming cytoskeletal JOKFNDED_02338 1396418.BATQ01000067_gene1719 3.2e-25 122.9 Verrucomicrobiae CP_0328 Bacteria 2IW9H@203494,46WDW@74201,COG1664@1,COG1664@2 NA|NA|NA M Polymer-forming cytoskeletal JOKFNDED_02339 1396141.BATP01000056_gene3198 4.8e-131 474.2 Verrucomicrobiae nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919 Bacteria 2ITV3@203494,46SA1@74201,COG0379@1,COG0379@2 NA|NA|NA H Quinolinate synthetase A protein JOKFNDED_02340 1403819.BATR01000112_gene3714 6.3e-48 197.2 Verrucomicrobiae Bacteria 2FADU@1,2IUDF@203494,342N6@2,46VMD@74201 NA|NA|NA JOKFNDED_02341 1403819.BATR01000134_gene4755 3e-36 160.6 Verrucomicrobiae ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IUIN@203494,46T9I@74201,COG1729@1,COG1729@2 NA|NA|NA S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division JOKFNDED_02343 1123508.JH636441_gene3126 2.4e-137 495.7 Planctomycetes 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 2IX0S@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_02344 1268622.AVS7_02480 1.6e-56 227.3 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2,COG3055@1,COG3055@2,COG3391@1,COG3391@2 NA|NA|NA G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses JOKFNDED_02347 1403819.BATR01000171_gene5872 1.5e-68 266.5 Verrucomicrobia 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 R00191 RC00296 ko00000,ko00001,ko01000 Bacteria 46TUP@74201,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain JOKFNDED_02348 1403819.BATR01000163_gene5513 4.6e-72 278.1 Verrucomicrobiae cvfB ko:K00243 ko00000 Bacteria 2IUBB@203494,46U3H@74201,COG2996@1,COG2996@2 NA|NA|NA S S1 domain JOKFNDED_02349 1396418.BATQ01000113_gene4670 7.3e-51 207.2 Verrucomicrobiae ydjA Bacteria 2IVRH@203494,46VPP@74201,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family JOKFNDED_02350 595460.RRSWK_05140 1.8e-79 303.5 Bacteria Bacteria 28JVS@1,2Z9KP@2 NA|NA|NA JOKFNDED_02351 1396141.BATP01000039_gene1319 2.8e-106 392.1 Verrucomicrobiae splB Bacteria 2ITTT@203494,46S99@74201,COG1533@1,COG1533@2 NA|NA|NA L Elongator protein 3, MiaB family, Radical SAM JOKFNDED_02352 344747.PM8797T_13053 1.6e-94 353.2 Planctomycetes Bacteria 2J28X@203682,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase JOKFNDED_02353 237368.SCABRO_03050 2.6e-08 64.3 Bacteria Bacteria 2DSNR@1,33GUE@2 NA|NA|NA JOKFNDED_02354 1403819.BATR01000069_gene2061 1.5e-150 539.3 Verrucomicrobiae Bacteria 2IV3H@203494,46X9A@74201,COG4447@1,COG4447@2 NA|NA|NA S cellulose binding JOKFNDED_02355 1403819.BATR01000069_gene2060 5.2e-22 110.2 Verrucomicrobiae ko:K03636 ko04122,map04122 ko00000,ko00001 Bacteria 2IWG1@203494,46XS2@74201,COG1977@1,COG1977@2 NA|NA|NA H ThiS family JOKFNDED_02356 1049564.TevJSym_al00310 0.0 1164.4 unclassified Gammaproteobacteria fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1J5CY@118884,1MUCV@1224,1RNNJ@1236,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome JOKFNDED_02357 1403819.BATR01000094_gene2963 3e-13 80.5 Verrucomicrobiae Bacteria 2BKFU@1,2IW91@203494,32EWN@2,46X05@74201 NA|NA|NA S Cysteine-rich CPXCG JOKFNDED_02358 497964.CfE428DRAFT_0075 1.7e-73 284.3 Verrucomicrobia 1.14.99.50 ko:K18912 ko00340,map00340 R11013 RC03323,RC03324 ko00000,ko00001,ko01000 Bacteria 46TPR@74201,COG1262@1,COG1262@2,COG2204@1,COG2204@2 NA|NA|NA T Sulfatase-modifying factor enzyme 1 JOKFNDED_02359 1403819.BATR01000042_gene1238 1.2e-25 124.4 Verrucomicrobiae Bacteria 2IUS8@203494,46TAX@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_02360 1123070.KB899248_gene120 8.9e-13 79.7 Verrucomicrobiae Bacteria 2IUN4@203494,46X69@74201,COG1664@1,COG1664@2 NA|NA|NA M Polymer-forming cytoskeletal JOKFNDED_02361 398767.Glov_3582 4.6e-18 98.2 Deltaproteobacteria Bacteria 1P3V9@1224,2ECUE@1,2WX45@28221,336RY@2,431ZA@68525 NA|NA|NA JOKFNDED_02362 240016.ABIZ01000001_gene633 2.4e-32 146.4 Verrucomicrobia yxaI Bacteria 46T8Y@74201,COG1714@1,COG1714@2 NA|NA|NA S RDD family JOKFNDED_02363 794903.OPIT5_15845 7.7e-14 85.5 Opitutae Bacteria 2CMJG@1,32SEZ@2,3K978@414999,46T0G@74201 NA|NA|NA JOKFNDED_02364 1403819.BATR01000144_gene4950 6e-17 93.2 Bacteria moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 ko:K03636,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria COG1977@1,COG1977@2 NA|NA|NA H Mo-molybdopterin cofactor metabolic process JOKFNDED_02365 497964.CfE428DRAFT_6292 7.1e-53 213.8 Verrucomicrobia hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 Bacteria 46T02@74201,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family JOKFNDED_02366 395019.Bmul_0728 2e-62 245.7 Burkholderiaceae pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1JZMU@119060,1NZUU@1224,2VIXW@28216,COG0259@1,COG0259@2 NA|NA|NA H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) JOKFNDED_02367 1396141.BATP01000006_gene5436 1.6e-39 169.1 Verrucomicrobiae Bacteria 2IUD2@203494,46VKR@74201,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein JOKFNDED_02368 1403819.BATR01000010_gene329 7.7e-10 70.9 Verrucomicrobiae Bacteria 2BMTH@1,2IW3A@203494,32GD1@2,46WZU@74201 NA|NA|NA JOKFNDED_02369 331869.BAL199_18771 1.1e-25 123.2 unclassified Alphaproteobacteria 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 1MY2R@1224,2U9FW@28211,4BR0W@82117,COG0295@1,COG0295@2 NA|NA|NA F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis JOKFNDED_02370 933262.AXAM01000018_gene994 1.2e-14 85.5 Proteobacteria Bacteria 1N9VU@1224,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 JOKFNDED_02371 497964.CfE428DRAFT_2071 1.4e-102 379.4 Bacteria Bacteria COG5285@1,COG5285@2 NA|NA|NA Q dioxygenase activity JOKFNDED_02372 240016.ABIZ01000001_gene2686 4.8e-129 468.0 Verrucomicrobiae Bacteria 2IVMH@203494,46UDN@74201,COG3458@1,COG3458@2 NA|NA|NA Q Acetyl xylan esterase (AXE1) JOKFNDED_02373 794903.OPIT5_09235 1.6e-75 289.7 Verrucomicrobia budR GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 Bacteria 46TZT@74201,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain JOKFNDED_02376 452637.Oter_0305 2.3e-128 465.3 Bacteria Bacteria COG0535@1,COG0535@2 NA|NA|NA I radical SAM domain protein JOKFNDED_02377 452637.Oter_0303 2.7e-112 412.1 Bacteria ko:K03306 ko00000 2.A.20 Bacteria COG0306@1,COG0306@2 NA|NA|NA P phosphate transporter JOKFNDED_02379 382464.ABSI01000020_gene219 0.0 1233.4 Bacteria Bacteria COG1002@1,COG1002@2 NA|NA|NA V DNA modification JOKFNDED_02380 483219.LILAB_03770 2.3e-160 572.0 Myxococcales cusA ko:K07787,ko:K15726 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 iAF987.Gmet_1547 Bacteria 1NUIV@1224,2WK3X@28221,2YUB0@29,42NCZ@68525,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family JOKFNDED_02381 1123274.KB899409_gene536 8.5e-11 74.3 Bacteria 5.2.1.8 ko:K03769,ko:K07533 ko00000,ko01000,ko03110 Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity JOKFNDED_02382 1396141.BATP01000003_gene4959 3.7e-13 80.5 Verrucomicrobiae tatA ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IURB@203494,46WPX@74201,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system JOKFNDED_02383 1146883.BLASA_4185 6.9e-193 680.2 Frankiales aldA 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4ES72@85013,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family JOKFNDED_02384 1121930.AQXG01000001_gene1487 1.8e-98 365.9 Bacteroidetes deoC 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 Bacteria 4NGE3@976,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate JOKFNDED_02387 794903.OPIT5_27940 1.4e-42 179.9 Opitutae ko:K03088 ko00000,ko03021 Bacteria 3K8W5@414999,46YS4@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_02388 1296416.JACB01000026_gene3952 2.9e-137 497.7 Aquimarina ko:K13276 ko00000,ko01000,ko01002,ko03110 Bacteria 1I7A8@117743,2YKAC@290174,4NIPP@976,COG1858@1,COG1858@2,COG3209@1,COG3209@2,COG3291@1,COG3291@2,COG3391@1,COG3391@2,COG4733@1,COG4733@2,COG5276@1,COG5276@2 NA|NA|NA MP Cellulose binding domain JOKFNDED_02390 240016.ABIZ01000001_gene2151 7.4e-150 537.0 Verrucomicrobiae metB 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IWMK@203494,46V6V@74201,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme JOKFNDED_02391 1123070.KB899251_gene787 4.5e-102 378.6 Verrucomicrobiae 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITMP@203494,46UUN@74201,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme JOKFNDED_02393 240016.ABIZ01000001_gene734 1.7e-21 109.4 Verrucomicrobia Bacteria 2DDR6@1,2ZIZ7@2,46WQK@74201 NA|NA|NA JOKFNDED_02395 344747.PM8797T_07534 3.2e-127 461.8 Planctomycetes 3.2.1.8 ko:K01181,ko:K06889 ko00000,ko01000 Bacteria 2IWT8@203682,COG1073@1,COG1073@2 NA|NA|NA S alpha beta JOKFNDED_02396 1227352.C173_17906 9.7e-07 60.8 Paenibacillaceae Bacteria 1VGNZ@1239,2738C@186822,4IDJZ@91061,COG3755@1,COG3755@2 NA|NA|NA S Pfam:DUF1311 JOKFNDED_02398 1403819.BATR01000087_gene2581 5e-155 554.3 Verrucomicrobiae ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2ITH0@203494,46SDM@74201,COG0443@1,COG0443@2 NA|NA|NA O MreB/Mbl protein JOKFNDED_02401 1123242.JH636436_gene396 2e-105 389.0 Planctomycetes ko:K09930 ko00000 Bacteria 2IY8B@203682,COG3220@1,COG3220@2 NA|NA|NA S Protein of unknown function (DUF692) JOKFNDED_02403 762211.BSTEL_1561 9.8e-40 171.8 Actinobacteria Bacteria 2B065@1,2H3VM@201174,31SGV@2 NA|NA|NA JOKFNDED_02404 756272.Plabr_3077 1.4e-256 892.5 Planctomycetes Bacteria 2J2BQ@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_02405 756272.Plabr_3078 2.7e-199 701.4 Planctomycetes Bacteria 2J21U@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_02406 177439.DP1520 3.4e-53 218.4 Desulfobacterales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1MXIP@1224,2MNJ9@213118,2WQ54@28221,42TFA@68525,COG3210@1,COG3210@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_02408 497964.CfE428DRAFT_6642 2.3e-07 63.5 Verrucomicrobia Bacteria 2EP8I@1,33GV9@2,46VKV@74201 NA|NA|NA JOKFNDED_02409 1123251.ATWM01000003_gene1150 1.4e-09 68.9 Actinobacteria GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 Bacteria 2DSUP@1,2GV46@201174,33HGU@2 NA|NA|NA JOKFNDED_02410 314278.NB231_16453 3.6e-33 147.9 Gammaproteobacteria GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 ko:K07064 ko00000 Bacteria 1RK9K@1224,1SBYF@1236,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_02412 767817.Desgi_3535 1.7e-09 68.6 Clostridia Bacteria 1VDA0@1239,24MUF@186801,COG1396@1,COG1396@2 NA|NA|NA K helix-turn-helix JOKFNDED_02414 1297742.A176_06847 4.2e-41 175.6 Deltaproteobacteria Bacteria 1R7HC@1224,2WM81@28221,42Q7A@68525,COG2199@1,COG2203@1,COG2203@2,COG3706@2 NA|NA|NA T GAF domain JOKFNDED_02415 1121930.AQXG01000012_gene3215 1.4e-263 915.6 Bacteroidetes hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 4NF2I@976,COG3808@1,COG3808@2 NA|NA|NA C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane JOKFNDED_02418 1403819.BATR01000183_gene6323 3.1e-07 62.8 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_02419 1403819.BATR01000183_gene6323 1.3e-10 73.9 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_02421 382464.ABSI01000005_gene1408 3.9e-33 148.3 Verrucomicrobiae pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU4N@203494,46YZ3@74201,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) JOKFNDED_02422 349741.Amuc_1223 4.3e-77 294.7 Verrucomicrobiae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2IU2E@203494,46YTH@74201,COG0284@1,COG0284@2 NA|NA|NA F Orotidine 5'-phosphate decarboxylase / HUMPS family JOKFNDED_02423 580332.Slit_0260 2.1e-09 68.2 Nitrosomonadales algR ko:K02477,ko:K08083 ko02020,map02020 M00493 ko00000,ko00001,ko00002,ko02022 Bacteria 1MUE8@1224,2WEFP@28216,44V6W@713636,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain JOKFNDED_02424 1163617.SCD_n02801 8.7e-12 76.3 Betaproteobacteria algZ 2.7.13.3 ko:K08082 ko02020,map02020 M00493 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MXVQ@1224,2VH9S@28216,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase JOKFNDED_02425 371731.Rsw2DRAFT_2179 2e-44 186.4 Rhodobacter dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1FB82@1060,1MVEN@1224,2TR5H@28211,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein JOKFNDED_02426 882378.RBRH_01124 2.1e-27 129.8 Betaproteobacteria Bacteria 1RKTS@1224,29597@1,2W21T@28216,2ZSMJ@2 NA|NA|NA S Protein of unknown function (DUF3037) JOKFNDED_02427 1403819.BATR01000164_gene5606 2.9e-29 135.2 Verrucomicrobiae Bacteria 29ZAN@1,2IVZU@203494,30M91@2,46XIB@74201 NA|NA|NA JOKFNDED_02428 1396418.BATQ01000147_gene3596 1.1e-142 514.2 Verrucomicrobiae mrdA 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 2ITKB@203494,46TSQ@74201,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain JOKFNDED_02430 1403819.BATR01000087_gene2571 4.6e-206 724.2 Verrucomicrobiae uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2IU0I@203494,46SAJ@74201,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision JOKFNDED_02431 452637.Oter_1864 5.4e-35 154.8 Verrucomicrobia ko:K02616 ko00000,ko03000 Bacteria 46W9G@74201,COG3327@1,COG3327@2 NA|NA|NA K negative regulation of DNA-templated transcription, initiation JOKFNDED_02432 1396418.BATQ01000008_gene1527 6.2e-68 264.6 Verrucomicrobiae potG 3.6.3.30 ko:K02010 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 Bacteria 2ITPH@203494,46SFH@74201,COG3842@1,COG3842@2 NA|NA|NA E ATPases associated with a variety of cellular activities JOKFNDED_02433 794903.OPIT5_02595 1.3e-94 354.0 Bacteria fbpB ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria COG1178@1,COG1178@2 NA|NA|NA P thiamine transport JOKFNDED_02434 1403819.BATR01000022_gene769 2.8e-95 355.5 Bacteria futA1 GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 iJN678.sufA Bacteria COG1840@1,COG1840@2 NA|NA|NA P iron ion homeostasis JOKFNDED_02436 1396418.BATQ01000058_gene76 0.0 1145.6 Verrucomicrobiae ccmA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 3.6.3.27,3.6.3.55 ko:K01990,ko:K06021,ko:K06857,ko:K21397 ko02010,map02010 M00186,M00254 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.6.2,3.A.1.6.4 Bacteria 2ITSH@203494,46TJ4@74201,COG0842@1,COG0842@2,COG1131@1,COG1131@2 NA|NA|NA V ABC-2 type transporter JOKFNDED_02438 497964.CfE428DRAFT_5303 1.1e-99 370.2 Verrucomicrobia cbf ko:K03698 ko00000,ko01000,ko03019 Bacteria 46SYB@74201,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. JOKFNDED_02439 240016.ABIZ01000001_gene3078 3.2e-230 804.3 Verrucomicrobiae Bacteria 2ITW7@203494,46U8M@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_02440 240016.ABIZ01000001_gene3077 0.0 1319.7 Verrucomicrobiae Bacteria 2ITZG@203494,46TEX@74201,COG2010@1,COG2010@2 NA|NA|NA C Concanavalin A-like lectin/glucanases superfamily JOKFNDED_02441 240016.ABIZ01000001_gene4115 3.9e-87 328.9 Verrucomicrobiae lnt ko:K03820 ko00000,ko01000 GT2 Bacteria 2IU1H@203494,46SPW@74201,COG0815@1,COG0815@2 NA|NA|NA M Carbon-nitrogen hydrolase JOKFNDED_02442 1396141.BATP01000039_gene1247 3.3e-73 282.0 Verrucomicrobiae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVHB@203494,46UDE@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_02443 1396418.BATQ01000029_gene5655 2.4e-34 152.1 Verrucomicrobiae Bacteria 2IW29@203494,46VT8@74201,COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif JOKFNDED_02444 1396418.BATQ01000029_gene5654 8.7e-22 110.5 Verrucomicrobiae Bacteria 2ETM2@1,2IW23@203494,33M4S@2,46WNN@74201 NA|NA|NA JOKFNDED_02445 1123070.KB899249_gene417 2.3e-122 446.0 Verrucomicrobiae murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 iECO103_1326.ECO103_1114 Bacteria 2IUHC@203494,46SH1@74201,COG0728@1,COG0728@2 NA|NA|NA S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane JOKFNDED_02447 1168034.FH5T_08055 2.4e-62 246.5 Bacteria ko:K17713 ko00000,ko02000 1.B.33.1 Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_02448 497964.CfE428DRAFT_2602 4.3e-144 518.1 Verrucomicrobia rpoN ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 46SDZ@74201,COG1508@1,COG1508@2 NA|NA|NA K TIGRFAM RNA polymerase sigma-54 factor, RpoN JOKFNDED_02449 1123070.KB899258_gene1891 1.1e-60 240.7 Verrucomicrobiae ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 2IUWB@203494,46ZHY@74201,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis/export protein JOKFNDED_02450 1123070.KB899258_gene1892 1.7e-69 270.0 Verrucomicrobiae pslD ko:K01991,ko:K20987 ko02025,ko02026,map02025,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 2IVGU@203494,46XCW@74201,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis/export protein JOKFNDED_02451 1403819.BATR01000168_gene5783 1.1e-128 466.5 Verrucomicrobiae Bacteria 2IVCN@203494,46SY6@74201,COG2013@1,COG2013@2 NA|NA|NA S Mitochondrial biogenesis AIM24 JOKFNDED_02452 439235.Dalk_2829 6.5e-216 757.3 Desulfobacterales yyaL ko:K06888 ko00000 Bacteria 1MUUT@1224,2MIHW@213118,2WJ7Y@28221,42MP3@68525,COG1331@1,COG1331@2 NA|NA|NA O Protein of unknown function, DUF255 JOKFNDED_02453 497964.CfE428DRAFT_3145 5.5e-209 734.6 Verrucomicrobia Bacteria 46TV0@74201,COG0715@1,COG0715@2,COG4191@1,COG4191@2 NA|NA|NA T ATP-binding region ATPase domain protein JOKFNDED_02454 240016.ABIZ01000001_gene3774 1.8e-102 379.8 Verrucomicrobia spmB ko:K06373,ko:K06374 ko00000 Bacteria 46TMH@74201,COG0700@1,COG0700@2,COG2715@1,COG2715@2 NA|NA|NA S Nucleoside recognition JOKFNDED_02455 697282.Mettu_3684 2.5e-27 128.3 Methylococcales Bacteria 1N7HB@1224,1SF7K@1236,1XGMP@135618,2E3V1@1,32YSA@2 NA|NA|NA JOKFNDED_02456 344747.PM8797T_20523 1.3e-165 589.7 Planctomycetes Bacteria 2J22P@203682,COG1409@1,COG1409@2 NA|NA|NA S PFAM Calcineurin-like phosphoesterase JOKFNDED_02457 1403819.BATR01000096_gene3059 2e-285 988.4 Verrucomicrobiae Bacteria 2IV9W@203494,46TXN@74201,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog JOKFNDED_02459 402881.Plav_2044 2.1e-57 229.2 Rhodobiaceae ko:K08714 ko00000,ko02000 1.A.1.14 Bacteria 1JNFD@119043,1MXKM@1224,2TSNZ@28211,2Z7ZD@2,COG1226@1 NA|NA|NA P Polycystin cation channel JOKFNDED_02460 794903.OPIT5_16300 5.6e-66 258.1 Opitutae Bacteria 3K9AV@414999,46YCE@74201,COG5464@1,COG5464@2 NA|NA|NA S Putative transposase, YhgA-like JOKFNDED_02461 497964.CfE428DRAFT_1814 0.0 1337.8 Bacteria ko:K09992 ko00000 Bacteria COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG3828@1,COG3828@2 NA|NA|NA N Trehalose utilisation JOKFNDED_02462 1403819.BATR01000042_gene1246 1.6e-71 276.2 Verrucomicrobiae 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IURK@203494,46SKI@74201,COG0266@1,COG0266@2 NA|NA|NA L Formamidopyrimidine-DNA glycosylase H2TH domain JOKFNDED_02463 1030157.AFMP01000005_gene3139 3.1e-34 154.1 Sphingomonadales vag8 ko:K19231 ko00000,ko02000 1.B.12 Bacteria 1MU92@1224,2KENE@204457,2TX9B@28211,COG3210@1,COG3210@2,COG3468@1,COG3468@2,COG4625@1,COG4625@2 NA|NA|NA MU Autotransporter beta-domain JOKFNDED_02464 1396418.BATQ01000171_gene2977 8.1e-15 87.8 Verrucomicrobiae ko:K05802,ko:K15771,ko:K18642,ko:K20444 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000,ko04812 1.A.23.1.1,3.A.1.1.16,3.A.1.1.2,4.D.1.3 GT2,GT4 Bacteria 2IUTM@203494,46WAF@74201,COG5185@1,COG5185@2 NA|NA|NA D Phage-related minor tail protein JOKFNDED_02466 1396418.BATQ01000105_gene5374 1.5e-32 146.0 Verrucomicrobiae ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 2IW1T@203494,46WJX@74201,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-monophosphate binding domain JOKFNDED_02467 1403819.BATR01000129_gene4564 1.4e-26 125.9 Verrucomicrobiae Bacteria 2DR24@1,2IWHQ@203494,339UE@2,46XSX@74201 NA|NA|NA S Protein of unknown function (DUF3307) JOKFNDED_02468 1396418.BATQ01000175_gene2825 4.4e-115 421.8 Verrucomicrobiae ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 2IVM7@203494,46SM7@74201,COG0793@1,COG0793@2 NA|NA|NA M tail specific protease JOKFNDED_02469 1396141.BATP01000022_gene409 6.6e-102 377.5 Verrucomicrobiae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2ITUT@203494,46SEH@74201,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction JOKFNDED_02470 929562.Emtol_2851 7.1e-123 447.6 Cytophagia Bacteria 47JCP@768503,4NF9M@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_02476 395493.BegalDRAFT_0085 1.9e-93 350.5 Thiotrichales ko:K01993,ko:K13408,ko:K16922 ko04626,map04626 M00339 ko00000,ko00001,ko00002,ko01002,ko02000,ko02044 8.A.1 Bacteria 1MW9I@1224,1RRTY@1236,4603C@72273,COG0845@1,COG0845@2,COG1994@1,COG1994@2 NA|NA|NA M Peptidase M50 JOKFNDED_02477 240016.ABIZ01000001_gene1223 5.1e-50 206.1 Verrucomicrobiae ko:K01991,ko:K02005,ko:K06147,ko:K16552 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18,1.B.18.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2IW3M@203494,46W00@74201,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like JOKFNDED_02478 240016.ABIZ01000001_gene1381 2.4e-169 603.2 Verrucomicrobiae Bacteria 2ITMY@203494,46U9B@74201,COG0457@1,COG0457@2 NA|NA|NA S Peptidase MA superfamily JOKFNDED_02479 2074.JNYD01000012_gene432 1.4e-47 196.4 Pseudonocardiales maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2GNI0@201174,4E2ME@85010,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein JOKFNDED_02481 452637.Oter_1098 7.7e-17 92.8 Opitutae Bacteria 3K9Z2@414999,46VQE@74201,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen JOKFNDED_02483 452637.Oter_0301 2e-158 565.5 Verrucomicrobia 2.1.1.137 ko:K07755 ko00000,ko01000 Bacteria 46TWV@74201,COG0500@1,COG2226@2 NA|NA|NA Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) JOKFNDED_02484 382464.ABSI01000011_gene2994 4.5e-50 204.1 Verrucomicrobiae Bacteria 2DQ7E@1,2IUQR@203494,3353C@2,46SU5@74201 NA|NA|NA S Domain of unknown function (DUF5069) JOKFNDED_02485 246197.MXAN_0990 4.3e-59 235.7 Myxococcales Bacteria 1PCPQ@1224,2WU8U@28221,2Z2R6@29,42PU9@68525,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_02486 1279017.AQYJ01000029_gene3977 3.7e-84 319.3 Alteromonadaceae cebB ko:K07798 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 Bacteria 1MVAS@1224,1RPBZ@1236,464X2@72275,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_02489 1403819.BATR01000114_gene3966 1.1e-84 320.5 Verrucomicrobiae rsmB 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392,ko:K21970 ko00000,ko01000,ko03009,ko03029 Bacteria 2ITWQ@203494,46TY0@74201,COG0144@1,COG0144@2 NA|NA|NA J 16S rRNA methyltransferase RsmB/F JOKFNDED_02490 1123401.JHYQ01000021_gene1008 7.5e-51 207.2 Thiotrichales ko:K07394 ko00000 Bacteria 1RD3H@1224,1S40I@1236,46161@72273,COG3751@1,COG3751@2 NA|NA|NA O 2OG-Fe(II) oxygenase JOKFNDED_02491 1123242.JH636434_gene5542 1.3e-61 243.4 Bacteria envE 3.1.4.46,3.2.1.18,3.2.1.8 ko:K01126,ko:K01181,ko:K01186 ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142 R01030,R01470,R04018 RC00017,RC00028,RC00077,RC00425 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria COG1413@1,COG1413@2,COG2755@1,COG2755@2,COG4409@1,COG4409@2 NA|NA|NA G exo-alpha-(2->6)-sialidase activity JOKFNDED_02492 1123242.JH636434_gene5547 4.3e-69 268.1 Bacteria 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 Bacteria COG3836@1,COG3836@2 NA|NA|NA G 2-keto-3-deoxy-L-rhamnonate aldolase activity JOKFNDED_02493 1123242.JH636434_gene5052 2.6e-104 385.6 Planctomycetes thrC 2.5.1.76,4.2.3.1 ko:K01733,ko:K15527 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXM9@203682,COG0498@1,COG0498@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme JOKFNDED_02494 1123242.JH636434_gene5545 5e-86 324.3 Planctomycetes ko:K06987 ko00000 Bacteria 2IYZ6@203682,COG3608@1,COG3608@2 NA|NA|NA S Succinylglutamate desuccinylase / Aspartoacylase family JOKFNDED_02495 1396141.BATP01000031_gene4782 3.6e-247 860.9 Verrucomicrobiae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 2ITMA@203494,46SID@74201,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 JOKFNDED_02496 521674.Plim_3412 7.3e-19 101.3 Bacteria Bacteria 2EIRT@1,33CH6@2 NA|NA|NA JOKFNDED_02497 1396141.BATP01000004_gene5891 6e-72 277.7 Verrucomicrobiae nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU3B@203494,46SPY@74201,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, N-terminal domain JOKFNDED_02498 497964.CfE428DRAFT_4997 3.1e-30 139.0 Verrucomicrobia birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 46SX6@74201,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family JOKFNDED_02499 314230.DSM3645_25924 4.4e-56 225.7 Planctomycetes Bacteria 2IXDR@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins JOKFNDED_02501 448385.sce6745 3.4e-44 187.2 Myxococcales Bacteria 1MWRF@1224,2WJI7@28221,2YTSQ@29,42P9S@68525,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA H CHAT domain JOKFNDED_02503 1407650.BAUB01000003_gene874 6.4e-15 87.0 Synechococcus rbpD Bacteria 1G7Q7@1117,1H17G@1129,COG0724@1,COG0724@2 NA|NA|NA S RNA-binding protein JOKFNDED_02504 1396418.BATQ01000001_gene1260 1.8e-43 182.6 Verrucomicrobiae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IV0F@203494,46VAR@74201,COG2094@1,COG2094@2 NA|NA|NA L Methylpurine-DNA glycosylase (MPG) JOKFNDED_02505 240016.ABIZ01000001_gene1151 4.6e-166 590.9 Verrucomicrobia Bacteria 46TZN@74201,COG0535@1,COG0535@2 NA|NA|NA S radical SAM domain protein JOKFNDED_02506 1396418.BATQ01000141_gene3325 2.3e-78 298.9 Bacteria 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria COG1830@1,COG1830@2 NA|NA|NA G lyase activity JOKFNDED_02507 1396141.BATP01000029_gene2250 9.2e-18 97.8 Verrucomicrobiae Bacteria 2IWGX@203494,46WA1@74201,COG1525@1,COG1525@2 NA|NA|NA L nuclease JOKFNDED_02509 1120965.AUBV01000010_gene2772 2.2e-42 178.7 Cytophagia Bacteria 47PZU@768503,4NMAH@976,COG2335@1,COG2335@2 NA|NA|NA M Fasciclin domain JOKFNDED_02512 349124.Hhal_0730 4.3e-54 218.8 Chromatiales pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUYP@1224,1RNEN@1236,1WXAJ@135613,COG0418@1,COG0418@2 NA|NA|NA F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate JOKFNDED_02513 243090.RB736 1.9e-65 255.8 Planctomycetes 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 2J3P7@203682,COG3408@1,COG3408@2,COG3828@1,COG3828@2 NA|NA|NA G Bacterial alpha-L-rhamnosidase C-terminal domain JOKFNDED_02514 497964.CfE428DRAFT_5491 1.8e-87 329.3 Verrucomicrobia Bacteria 46SVI@74201,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold JOKFNDED_02515 1122605.KB893637_gene3264 5.7e-07 62.8 Bacteroidetes 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 4P27R@976,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_02516 344747.PM8797T_31188 6e-79 300.8 Bacteria Bacteria COG3828@1,COG3828@2 NA|NA|NA N Trehalose utilisation JOKFNDED_02517 497964.CfE428DRAFT_4428 2.4e-83 315.5 Verrucomicrobia Bacteria 46U6B@74201,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase JOKFNDED_02518 1396418.BATQ01000008_gene1480 5.8e-76 290.4 Verrucomicrobiae clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2ITX1@203494,46SAB@74201,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins JOKFNDED_02519 1396141.BATP01000047_gene3978 2.8e-32 144.8 Bacteria Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_02520 1396141.BATP01000047_gene3979 3e-11 74.3 Bacteria ko:K21495 ko00000,ko02048 Bacteria COG4691@1,COG4691@2 NA|NA|NA S Plasmid stability protein JOKFNDED_02522 1396141.BATP01000005_gene6094 2.9e-52 211.8 Verrucomicrobiae ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 2IUFH@203494,46T2E@74201,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily JOKFNDED_02531 1403819.BATR01000191_gene6506 2.1e-129 468.8 Verrucomicrobiae appF ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2ITPK@203494,46U8E@74201,COG4608@1,COG4608@2 NA|NA|NA E Oligopeptide/dipeptide transporter, C-terminal region JOKFNDED_02532 1396141.BATP01000057_gene3092 2.5e-106 392.1 Verrucomicrobiae dppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2IU2Y@203494,46YTM@74201,COG0444@1,COG0444@2 NA|NA|NA EP Oligopeptide/dipeptide transporter, C-terminal region JOKFNDED_02533 1396141.BATP01000057_gene3091 2.1e-179 636.0 Verrucomicrobiae ko:K13893 ko02010,map02010 M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 Bacteria 2ITVT@203494,46UFF@74201,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle JOKFNDED_02534 1396141.BATP01000057_gene3090 2.1e-112 412.9 Verrucomicrobiae yejE ko:K13895 ko02010,map02010 M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 Bacteria 2ITTS@203494,46UMY@74201,COG4239@1,COG4239@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component JOKFNDED_02535 1396141.BATP01000057_gene3089 7.1e-117 427.6 Verrucomicrobiae oppB ko:K02033,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 2ITNK@203494,46TSV@74201,COG0601@1,COG0601@2,COG4174@1,COG4174@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component JOKFNDED_02536 1396418.BATQ01000152_gene2378 9.7e-22 109.4 Verrucomicrobiae Bacteria 2CGAT@1,2IUVU@203494,335PS@2,46ZAD@74201 NA|NA|NA JOKFNDED_02537 240016.ABIZ01000001_gene3605 1e-19 105.9 Verrucomicrobiae Bacteria 2IVU3@203494,46XG7@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein kinase domain JOKFNDED_02538 1198232.CYCME_0437 9.3e-72 276.9 Thiotrichales cysQ 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1N0GY@1224,1RP5A@1236,460I9@72273,COG1218@1,COG1218@2 NA|NA|NA P Inositol monophosphatase family JOKFNDED_02539 240016.ABIZ01000001_gene3531 2e-13 82.8 Bacteria Bacteria COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif JOKFNDED_02540 1123070.KB899249_gene387 1.3e-164 587.0 Verrucomicrobiae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2ITHQ@203494,46U8T@74201,COG0557@1,COG0557@2 NA|NA|NA K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs JOKFNDED_02541 1396418.BATQ01000151_gene2365 7.6e-63 246.5 Verrucomicrobiae 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 2IUEU@203494,46T52@74201,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphatase family JOKFNDED_02542 580340.Tlie_1774 3.3e-139 501.5 Synergistetes arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 ko:K03325 ko00000,ko02000 2.A.59 Bacteria 3TC0V@508458,COG0798@1,COG0798@2 NA|NA|NA P PFAM Bile acid sodium symporter JOKFNDED_02543 643562.Daes_0503 2.5e-23 114.8 Desulfovibrionales arsR 3.6.4.12 ko:K03655,ko:K03892 ko03440,map03440 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1N19R@1224,2MC8X@213115,2WQHU@28221,42TRS@68525,COG0640@1,COG0640@2 NA|NA|NA K SMART regulatory protein ArsR JOKFNDED_02544 1396418.BATQ01000182_gene877 3.3e-92 345.5 Verrucomicrobiae Bacteria 2IVB9@203494,46VHB@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_02545 497964.CfE428DRAFT_2760 5.9e-64 251.9 Verrucomicrobia Bacteria 46U9P@74201,COG2148@1,COG2148@2 NA|NA|NA M TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase JOKFNDED_02546 1396141.BATP01000020_gene26 8.6e-21 109.0 Verrucomicrobiae ywqD 2.7.10.1 ko:K08252,ko:K13661,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 2IVHF@203494,46YXA@74201,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM Chain length determinant protein JOKFNDED_02547 161156.JQKW01000008_gene414 5.9e-13 82.4 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process JOKFNDED_02548 1286631.X805_13870 1.6e-21 110.9 Betaproteobacteria Bacteria 1N6ET@1224,2ADXV@1,2VU5N@28216,313Q2@2 NA|NA|NA JOKFNDED_02549 243159.AFE_0081 6e-50 204.9 Acidithiobacillales Bacteria 1N9EV@1224,1RYRV@1236,2NDKS@225057,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 JOKFNDED_02550 1122139.KB907865_gene1461 3.3e-85 322.0 Oceanospirillales Bacteria 1MXUX@1224,1RMTW@1236,1XPMH@135619,COG0604@1,COG0604@2 NA|NA|NA C NADPH quinone JOKFNDED_02551 1396418.BATQ01000049_gene421 6.9e-216 756.9 Verrucomicrobiae dpx ko:K02347 ko00000,ko03400 Bacteria 2ITWG@203494,46TH0@74201,COG1387@1,COG1387@2 NA|NA|NA L DNA polymerase X family JOKFNDED_02555 1396141.BATP01000039_gene1262 2.8e-168 598.2 Verrucomicrobiae ko:K19689 ko00000,ko01000,ko01002 Bacteria 2ITWS@203494,46SHB@74201,COG2309@1,COG2309@2 NA|NA|NA E aminopeptidase activity JOKFNDED_02556 323097.Nham_3479 1.9e-123 449.9 Bradyrhizobiaceae hbdA 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 ko:K00074,ko:K01782,ko:K07516 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9P@1224,2TR8E@28211,3JUAA@41294,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain JOKFNDED_02557 323098.Nwi_0754 1.2e-104 386.0 Bradyrhizobiaceae etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 ko:K03522 ko00000,ko04147 Bacteria 1MUFI@1224,2TR10@28211,3JRD2@41294,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein JOKFNDED_02558 378806.STAUR_6585 1.1e-11 76.6 Proteobacteria Bacteria 1NAB9@1224,COG2373@1,COG2373@2 NA|NA|NA KLT Cytochrome oxidase complex assembly protein 1 JOKFNDED_02559 497964.CfE428DRAFT_3171 7e-23 114.4 Verrucomicrobia ko:K06973 ko00000 Bacteria 46TH9@74201,COG2738@1,COG2738@2 NA|NA|NA S Putative neutral zinc metallopeptidase JOKFNDED_02560 313628.LNTAR_21350 2.3e-37 162.5 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity JOKFNDED_02561 1403819.BATR01000104_gene3489 8.7e-83 313.9 Verrucomicrobiae ycjG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 R10938 RC03309 ko00000,ko01000 iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620 Bacteria 2IW6N@203494,46WRJ@74201,COG4948@1,COG4948@2 NA|NA|NA M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain JOKFNDED_02562 240016.ABIZ01000001_gene2223 4.4e-105 388.3 Verrucomicrobiae 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 2IW3Z@203494,46VZE@74201,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain JOKFNDED_02563 1396141.BATP01000003_gene5211 5.4e-79 300.8 Verrucomicrobiae dedA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03975 ko00000 Bacteria 2IVM8@203494,46SWW@74201,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein JOKFNDED_02564 756272.Plabr_1070 8.7e-71 274.6 Bacteria 3.1.1.11 ko:K01051 ko00040,ko01100,map00040,map01100 M00081 R02362 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria COG0657@1,COG0657@2,COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_02565 1396141.BATP01000059_gene2619 2e-41 176.0 Verrucomicrobiae ywaF Bacteria 2IW7Y@203494,46WTQ@74201,COG5522@1,COG5522@2 NA|NA|NA S Integral membrane protein (intg_mem_TP0381) JOKFNDED_02566 1123070.KB899247_gene1479 1.3e-26 125.6 Verrucomicrobiae Bacteria 2DA6F@1,2IUV2@203494,32TUS@2,46WCG@74201 NA|NA|NA JOKFNDED_02567 1396141.BATP01000003_gene5105 1.2e-69 270.4 Verrucomicrobiae ko:K09805 ko00000 Bacteria 2IU9M@203494,46ZH0@74201,COG2958@1,COG2958@2 NA|NA|NA S Protein conserved in bacteria JOKFNDED_02568 530564.Psta_0542 3.2e-49 202.2 Planctomycetes Bacteria 2AU2S@1,2IZEE@203682,31JP5@2 NA|NA|NA S Domain of Unknown Function (DUF1080) JOKFNDED_02572 980584.AFPB01000091_gene14 7.4e-23 112.8 Flavobacteriia Bacteria 1HZZE@117743,4NFKA@976,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits JOKFNDED_02573 935836.JAEL01000101_gene4462 1.7e-08 65.9 Bacillus Bacteria 1TQUQ@1239,1ZD4W@1386,4HAXP@91061,COG0745@1,COG0745@2 NA|NA|NA T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain JOKFNDED_02574 243231.GSU2653 1.9e-107 396.4 Desulfuromonadales norM Bacteria 1MVRV@1224,2WIKH@28221,42PV5@68525,43UC2@69541,COG0534@1,COG0534@2 NA|NA|NA V PFAM multi antimicrobial extrusion protein MatE JOKFNDED_02575 794903.OPIT5_17790 1.3e-10 71.6 Verrucomicrobia phlE ko:K02511,ko:K02575,ko:K13021 ko00910,map00910 M00615 ko00000,ko00001,ko00002,ko02000 2.A.1.14.3,2.A.1.14.9,2.A.1.8 Bacteria 46Z9E@74201,COG0477@1,COG2814@2 NA|NA|NA EGP Sugar (and other) transporter JOKFNDED_02576 452637.Oter_1248 1.6e-12 79.3 Opitutae vapC ko:K07064 ko00000 Bacteria 3K8HY@414999,46XWY@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_02577 240016.ABIZ01000001_gene3307 2.7e-166 591.7 Verrucomicrobiae Bacteria 2IU79@203494,46SJ9@74201,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily JOKFNDED_02578 1396418.BATQ01000083_gene1164 1e-76 293.1 Verrucomicrobiae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 2ITND@203494,46S94@74201,COG0449@1,COG0449@2 NA|NA|NA M Glutamine amidotransferase domain JOKFNDED_02579 1396141.BATP01000003_gene4892 9.8e-32 143.3 Verrucomicrobiae Bacteria 2IUP5@203494,46SXP@74201,COG4747@1,COG4747@2 NA|NA|NA S ACT domain protein JOKFNDED_02580 1403819.BATR01000050_gene1452 7.6e-61 240.7 Verrucomicrobiae Bacteria 2IUV5@203494,46UT5@74201,COG1714@1,COG1714@2 NA|NA|NA S RDD family JOKFNDED_02581 398767.Glov_3575 4.3e-77 295.0 Deltaproteobacteria ko:K06384 ko00000 Bacteria 1Q1GN@1224,2WQQ0@28221,42UUJ@68525,COG1300@1,COG1300@2 NA|NA|NA S Stage II sporulation protein M JOKFNDED_02582 1403819.BATR01000137_gene4850 6.7e-200 703.7 Verrucomicrobiae xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2ITRF@203494,46TUR@74201,COG2804@1,COG2804@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_02583 1396418.BATQ01000133_gene4094 4.5e-211 740.7 Verrucomicrobiae purH 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITYZ@203494,46S5H@74201,COG0138@1,COG0138@2 NA|NA|NA F AICARFT/IMPCHase bienzyme JOKFNDED_02585 1403819.BATR01000103_gene3460 3.9e-122 444.9 Verrucomicrobiae aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITKA@203494,46UQ7@74201,COG0337@1,COG0337@2 NA|NA|NA E 3-dehydroquinate synthase JOKFNDED_02587 240016.ABIZ01000001_gene3058 7.6e-152 543.5 Verrucomicrobiae leuB GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082 Bacteria 2ITY1@203494,46S4R@74201,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate JOKFNDED_02589 756272.Plabr_2325 1.4e-67 262.3 Planctomycetes Bacteria 2IX1H@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_02595 314256.OG2516_11096 1.8e-92 346.7 Oceanicola Bacteria 1MX0S@1224,2DBJ8@1,2PF9K@252301,2TT7Z@28211,2Z9JM@2 NA|NA|NA S NAD-specific glutamate dehydrogenase JOKFNDED_02596 1396141.BATP01000022_gene331 3.8e-34 152.1 Verrucomicrobiae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IWCT@203494,46XQ3@74201,COG5184@1,COG5184@2 NA|NA|NA DZ Regulator of chromosome condensation (RCC1) repeat JOKFNDED_02598 1396418.BATQ01000007_gene1410 3e-24 118.2 Bacteria Bacteria 2AVPC@1,31MGE@2 NA|NA|NA JOKFNDED_02599 1396418.BATQ01000007_gene1408 4e-26 124.4 Verrucomicrobiae Bacteria 2DS4P@1,2IW5C@203494,33EH8@2,46XKS@74201 NA|NA|NA JOKFNDED_02601 314275.MADE_1009235 3.7e-60 238.0 Gammaproteobacteria ubiE2 Bacteria 1RAAZ@1224,1RR8C@1236,COG0500@1,COG2226@2 NA|NA|NA Q COG0500 SAM-dependent methyltransferases JOKFNDED_02602 1396418.BATQ01000063_gene1605 3.4e-18 97.1 Verrucomicrobia Bacteria 28UZZ@1,2ZH3M@2,46WX4@74201 NA|NA|NA JOKFNDED_02605 1123508.JH636444_gene5574 1.1e-161 576.6 Planctomycetes ko:K08482 ko00000 Bacteria 2IXDQ@203682,COG0467@1,COG0467@2 NA|NA|NA T COG0467 RecA-superfamily ATPases implicated in signal JOKFNDED_02606 1122603.ATVI01000010_gene926 1.7e-112 413.3 Xanthomonadales Bacteria 1NRP8@1224,1RQ3H@1236,1X3SI@135614,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_02608 1123242.JH636434_gene4724 2.5e-89 335.9 Planctomycetes 2.7.13.3 ko:K11527 ko00000,ko01000,ko01001,ko02022 Bacteria 2IWY2@203682,COG0642@1,COG0784@1,COG0784@2,COG2205@2,COG3437@1,COG3437@2 NA|NA|NA T Domain present in phytochromes and cGMP-specific phosphodiesterases. JOKFNDED_02611 756272.Plabr_4286 1e-225 789.3 Planctomycetes Bacteria 2IXKR@203682,COG4102@1,COG4102@2 NA|NA|NA T Protein of unknown function (DUF1501) JOKFNDED_02612 756272.Plabr_4287 1.3e-310 1072.4 Planctomycetes Bacteria 2IXZ4@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_02614 497964.CfE428DRAFT_4812 9.1e-84 317.0 Verrucomicrobia Bacteria 46UDF@74201,COG3386@1,COG3386@2 NA|NA|NA G SMP-30/Gluconolaconase/LRE-like region JOKFNDED_02615 1396418.BATQ01000014_gene4348 6.7e-38 164.1 Verrucomicrobia ko:K03088 ko00000,ko03021 Bacteria 46W6X@74201,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor JOKFNDED_02616 998674.ATTE01000001_gene1544 8.9e-81 307.0 Proteobacteria Bacteria 1NREG@1224,2DBRE@1,2ZAK7@2 NA|NA|NA JOKFNDED_02617 1396141.BATP01000047_gene3922 8.7e-127 460.3 Verrucomicrobiae pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITXY@203494,46SI9@74201,COG0126@1,COG0126@2 NA|NA|NA G Phosphoglycerate kinase JOKFNDED_02618 1123070.KB899250_gene619 1.3e-209 735.7 Verrucomicrobiae acsA 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2ITZ8@203494,46SBX@74201,COG0365@1,COG0365@2 NA|NA|NA I Acetyl-coenzyme A synthetase N-terminus JOKFNDED_02620 1396418.BATQ01000153_gene2252 9.4e-12 75.9 Verrucomicrobiae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUQF@203494,46WUR@74201,COG0828@1,COG0828@2 NA|NA|NA J Ribosomal protein S21 JOKFNDED_02625 522306.CAP2UW1_1318 4.3e-63 248.4 Betaproteobacteria Bacteria 1QG9J@1224,2VIRR@28216,COG3597@1,COG3597@2 NA|NA|NA P Tellurite resistance protein TerB JOKFNDED_02626 1089550.ATTH01000001_gene2215 2.4e-75 289.3 Bacteroidetes Order II. Incertae sedis GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 ko:K06955 ko00000 Bacteria 1FK25@1100069,4PJ84@976,COG3380@1,COG3380@2 NA|NA|NA S Flavin containing amine oxidoreductase JOKFNDED_02627 583355.Caka_1357 6.3e-62 244.2 Verrucomicrobia yafK Bacteria 46T6Y@74201,COG3034@1,COG3034@2 NA|NA|NA S peptidoglycan biosynthetic process JOKFNDED_02628 1347392.CCEZ01000029_gene1712 3.9e-53 215.7 Clostridiaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TPY1@1239,2483K@186801,36DK4@31979,COG0687@1,COG0687@2 NA|NA|NA P Spermidine putrescine-binding periplasmic protein JOKFNDED_02629 886293.Sinac_7175 8.3e-17 93.2 Bacteria ko:K12963 ko01503,map01503 M00721 ko00000,ko00001,ko00002,ko01005 2.A.7 Bacteria 2EIVR@1,33CM1@2 NA|NA|NA JOKFNDED_02630 717785.HYPMC_3214 7.3e-20 103.6 Hyphomicrobiaceae ko:K07117 ko00000 Bacteria 1N3VM@1224,2UDY0@28211,3N93Y@45401,COG2940@1,COG2940@2 NA|NA|NA S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain JOKFNDED_02631 1173026.Glo7428_0554 3.5e-27 128.3 Bacteria ko:K07117 ko00000 Bacteria COG2940@1,COG2940@2 NA|NA|NA K SET domain JOKFNDED_02632 1395571.TMS3_0104715 1.8e-35 157.1 Gammaproteobacteria ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1MUYW@1224,1RM7W@1236,COG0687@1,COG0687@2 NA|NA|NA P Required for the activity of the bacterial periplasmic transport system of putrescine JOKFNDED_02633 1396418.BATQ01000129_gene4823 1.2e-83 317.0 Verrucomicrobiae moeA 2.10.1.1,2.7.7.75 ko:K03750,ko:K15376 ko00790,ko01100,ko04727,map00790,map01100,map04727 R09726,R09735 RC00002,RC03462 ko00000,ko00001,ko01000 Bacteria 2IUKH@203494,46SZB@74201,COG0303@1,COG0303@2 NA|NA|NA H MoeA N-terminal region (domain I and II) JOKFNDED_02634 1396418.BATQ01000149_gene2220 6.2e-119 434.1 Verrucomicrobiae aroG1 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITP2@203494,46UK5@74201,COG0722@1,COG0722@2 NA|NA|NA E DAHP synthetase I family JOKFNDED_02635 349741.Amuc_0365 1.7e-43 183.3 Verrucomicrobiae crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10208 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IUH8@203494,46VIE@74201,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase JOKFNDED_02636 1403819.BATR01000032_gene1065 1e-202 713.0 Verrucomicrobiae rtcB 6.5.1.3 ko:K14415 ko00000,ko01000,ko03016 Bacteria 2IV9F@203494,46SU0@74201,COG1690@1,COG1690@2 NA|NA|NA S tRNA-splicing ligase RtcB JOKFNDED_02637 497964.CfE428DRAFT_3536 2.7e-49 201.8 Verrucomicrobia Bacteria 46VIF@74201,COG1376@1,COG1376@2 NA|NA|NA S PFAM ErfK YbiS YcfS YnhG family protein JOKFNDED_02638 1121272.KB903261_gene5930 8.2e-30 139.4 Micromonosporales 3.2.1.18,3.4.11.10 ko:K01186,ko:K05994 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko01002,ko02042 GH33 Bacteria 2I4PF@201174,4DC47@85008,COG3227@1,COG3227@2,COG4447@1,COG4447@2 NA|NA|NA E cellulose binding JOKFNDED_02639 290397.Adeh_3395 1.3e-53 216.9 Myxococcales ykfA 3.4.17.13 ko:K01297 ko00000,ko01000,ko01002,ko01011 Bacteria 1MWIY@1224,2WJ3S@28221,2Z0HR@29,42Q52@68525,COG1619@1,COG1619@2 NA|NA|NA V LD-carboxypeptidase JOKFNDED_02640 240016.ABIZ01000001_gene2402 1.3e-54 219.5 Verrucomicrobiae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808,ko:K05809 ko00000,ko03009 Bacteria 2IU7I@203494,46VGU@74201,COG1544@1,COG1544@2 NA|NA|NA J Sigma 54 modulation/S30EA ribosomal protein C terminus JOKFNDED_02641 240016.ABIZ01000001_gene2401 1.3e-90 340.5 Verrucomicrobiae lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 2IU2S@203494,46SDI@74201,COG1137@1,COG1137@2 NA|NA|NA S ATPases associated with a variety of cellular activities JOKFNDED_02643 1403819.BATR01000112_gene3716 6.9e-11 74.3 Verrucomicrobia Bacteria 2C4M2@1,2ZG2A@2,46WV2@74201 NA|NA|NA JOKFNDED_02644 240016.ABIZ01000001_gene4233 0.0 1091.3 Verrucomicrobiae Bacteria 2IV6M@203494,46UEW@74201,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family JOKFNDED_02645 583355.Caka_1928 4.4e-28 131.7 Verrucomicrobia 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 46UXZ@74201,COG0189@1,COG0189@2,COG0586@1,COG0586@2,COG1073@1,COG1073@2 NA|NA|NA HJ SNARE associated Golgi protein JOKFNDED_02646 1396418.BATQ01000142_gene3258 1.2e-122 446.4 Verrucomicrobia Bacteria 46UK6@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain JOKFNDED_02649 1396141.BATP01000057_gene3072 3.4e-12 79.7 Verrucomicrobiae Bacteria 29UBH@1,2IUW8@203494,30FMU@2,46ZI6@74201 NA|NA|NA JOKFNDED_02650 1396141.BATP01000057_gene3071 1.1e-23 117.1 Verrucomicrobiae Bacteria 2DK8U@1,2IUWG@203494,308WA@2,46ZIC@74201 NA|NA|NA JOKFNDED_02651 59931.WH7805_02612 5.1e-167 594.3 Synechococcus ko:K06876 ko00000 Bacteria 1G0W4@1117,1GYIJ@1129,COG3046@1,COG3046@2 NA|NA|NA S protein related to deoxyribodipyrimidine photolyase JOKFNDED_02652 1122176.KB903569_gene3486 3.2e-63 248.4 Sphingobacteriia Bacteria 1INM7@117747,4NFXD@976,COG1028@1,COG1028@2 NA|NA|NA IQ with different specificities (related to short-chain alcohol JOKFNDED_02654 1303518.CCALI_01606 3.6e-37 162.9 Bacteria ko:K14274,ko:K20276 ko00040,ko02024,map00040,map02024 R02427 RC00713 ko00000,ko00001,ko01000 Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity JOKFNDED_02655 1288963.ADIS_2836 7e-68 264.2 Cytophagia ko:K03453 ko00000 2.A.28 Bacteria 47QUN@768503,4NEIM@976,COG0385@1,COG0385@2 NA|NA|NA S PFAM Sodium Bile acid symporter family JOKFNDED_02657 756272.Plabr_2038 1.3e-110 406.8 Planctomycetes Bacteria 2J27C@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_02659 1396141.BATP01000032_gene4278 3.1e-92 346.7 Verrucomicrobiae Bacteria 2IV7Y@203494,46TQZ@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase JOKFNDED_02660 1396141.BATP01000021_gene181 3.1e-47 195.3 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IVT7@203494,46TV8@74201,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_02661 1396141.BATP01000003_gene4902 1.4e-32 146.0 Verrucomicrobiae Bacteria 2IW8R@203494,46T9K@74201,COG5485@1,COG5485@2 NA|NA|NA S SnoaL-like polyketide cyclase JOKFNDED_02662 1123278.KB893615_gene5179 3.9e-95 355.5 Cytophagia Bacteria 47PBP@768503,4NNEF@976,COG3386@1,COG3386@2,COG3391@1,COG3391@2 NA|NA|NA G NHL repeat JOKFNDED_02663 497964.CfE428DRAFT_1109 1.7e-161 575.9 Verrucomicrobia Bacteria 46TSF@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_02665 1123070.KB899247_gene1572 6.6e-130 470.7 Verrucomicrobiae rlmI 2.1.1.191,2.1.1.72 ko:K00571,ko:K06969 ko00000,ko01000,ko02048,ko03009 Bacteria 2ITMI@203494,46SJ5@74201,COG1092@1,COG1092@2 NA|NA|NA J S-adenosylmethionine-dependent methyltransferase JOKFNDED_02666 1396418.BATQ01000020_gene5063 8.4e-201 707.2 Verrucomicrobiae 1.1.9.1,1.8.2.2 ko:K02030,ko:K17760,ko:K19713 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2IVJP@203494,46UEX@74201,COG3258@1,COG3258@2 NA|NA|NA C PA14 JOKFNDED_02667 1403819.BATR01000059_gene1840 1.3e-174 619.4 Verrucomicrobiae Bacteria 2IV94@203494,46TJG@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_02668 1131814.JAFO01000001_gene270 9.8e-35 153.3 Xanthobacteraceae tspO GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 9.A.24 Bacteria 1MZC1@1224,2UBYB@28211,3EZMB@335928,COG3476@1,COG3476@2 NA|NA|NA T TspO/MBR family JOKFNDED_02669 240016.ABIZ01000001_gene1158 3.6e-133 481.5 Verrucomicrobiae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 2ITJY@203494,46UNB@74201,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit JOKFNDED_02670 762968.HMPREF9441_02069 6.5e-57 227.3 Bacteroidia engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 2FM4M@200643,4NEA9@976,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation JOKFNDED_02671 1396418.BATQ01000049_gene342 5.4e-61 241.1 Verrucomicrobiae Bacteria 2BVH5@1,2IVSU@203494,32QVT@2,46VTB@74201 NA|NA|NA S NlpC/P60 family JOKFNDED_02672 1210884.HG799463_gene9822 7.1e-45 189.1 Planctomycetes amiC1 ko:K11959 ko02010,map02010 M00323 ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 Bacteria 2IXZV@203682,COG0515@1,COG0515@2,COG0683@1,COG0683@2 NA|NA|NA E Periplasmic binding protein domain JOKFNDED_02673 595460.RRSWK_02828 8.2e-09 66.6 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZT4@203682,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_02676 240016.ABIZ01000001_gene3326 6.5e-37 161.4 Verrucomicrobiae dsbD 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 2IVVA@203494,46YXH@74201,COG4233@1,COG4233@2 NA|NA|NA CO Disulphide bond corrector protein DsbC JOKFNDED_02677 1123070.KB899251_gene803 1.3e-54 219.5 Verrucomicrobiae ko:K07117 ko00000 Bacteria 2IUGA@203494,46W0B@74201,COG2940@1,COG2940@2 NA|NA|NA S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain JOKFNDED_02678 1517682.HW49_06850 1.1e-06 60.5 Porphyromonadaceae mltD ko:K08307,ko:K12204 ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 22VZV@171551,2FM5V@200643,4NEKW@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2 NA|NA|NA M transglycosylase JOKFNDED_02679 1396141.BATP01000039_gene1364 3.1e-32 146.0 Verrucomicrobiae soxS 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 2IW7D@203494,46Z6E@74201,COG2143@1,COG2143@2 NA|NA|NA O Thioredoxin-like domain JOKFNDED_02680 240016.ABIZ01000001_gene3314 2.3e-56 226.9 Verrucomicrobiae peaA 1.4.9.1 ko:K08685 ko00680,ko01120,map00680,map01120 R00606 RC00189 ko00000,ko00001,ko01000 Bacteria 2IVQW@203494,46WAE@74201,COG2010@1,COG2010@2,COG3241@1,COG3241@2 NA|NA|NA C PA14 JOKFNDED_02681 1396141.BATP01000023_gene546 3.7e-162 578.2 Verrucomicrobiae Bacteria 2IWKI@203494,46TT9@74201,COG2133@1,COG2133@2 NA|NA|NA G pyrroloquinoline quinone binding JOKFNDED_02682 1396141.BATP01000020_gene24 1.7e-74 287.0 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process JOKFNDED_02683 1396141.BATP01000058_gene2001 6.9e-85 320.9 Verrucomicrobiae rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 2ITZF@203494,46SQY@74201,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil JOKFNDED_02684 395494.Galf_2633 2.3e-10 73.6 Proteobacteria 3.1.1.5,4.2.2.6 ko:K01730,ko:K10804 ko00040,ko01040,map00040,map01040 R04382 RC02124,RC02427 ko00000,ko00001,ko01000,ko01004 Bacteria 1NTK7@1224,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_02685 1280952.HJA_13440 1.9e-07 63.2 Hyphomonadaceae sigK ko:K03088 ko00000,ko03021 Bacteria 1RHRR@1224,2UYVT@28211,43Y61@69657,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_02686 452637.Oter_2580 2.2e-24 118.2 Opitutae ko:K03593 ko00000,ko03029,ko03036 Bacteria 3K8AJ@414999,46VNP@74201,COG3536@1,COG3536@2 NA|NA|NA S Protein of unknown function (DUF971) JOKFNDED_02688 1396141.BATP01000022_gene433 7.9e-127 461.5 Verrucomicrobiae ko:K12066 ko00000,ko02044 3.A.7.11.1 Bacteria 2ITPV@203494,46Z4D@74201,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II/III secretion system short domain JOKFNDED_02691 1403819.BATR01000051_gene1531 1.2e-64 254.6 Verrucomicrobiae Bacteria 29W31@1,2IUK6@203494,30HMQ@2,46XFE@74201 NA|NA|NA JOKFNDED_02692 1403819.BATR01000181_gene6201 1.6e-136 493.0 Verrucomicrobia Bacteria 46TSP@74201,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter JOKFNDED_02693 1123070.KB899253_gene1131 9e-58 231.1 Verrucomicrobiae Bacteria 2IU90@203494,46T7F@74201,COG1565@1,COG1565@2 NA|NA|NA S Putative S-adenosyl-L-methionine-dependent methyltransferase JOKFNDED_02694 240016.ABIZ01000001_gene401 7.8e-179 634.4 Verrucomicrobiae mtgA GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K03693,ko:K03814,ko:K04478,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K18770,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 iAF987.Gmet_1671 Bacteria 2ITVY@203494,46TMG@74201,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase JOKFNDED_02695 1280950.HJO_12721 1.8e-20 105.5 Hyphomonadaceae Bacteria 1RJJB@1224,2B9KW@1,2UAVD@28211,322Z5@2,43YZ5@69657 NA|NA|NA JOKFNDED_02696 243090.RB7875 8.3e-191 673.3 Planctomycetes Bacteria 2J22F@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_02697 1396418.BATQ01000166_gene1879 1e-46 194.1 Verrucomicrobiae iscA1 ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2IUGI@203494,46T1T@74201,COG0316@1,COG0316@2 NA|NA|NA S Iron-sulphur cluster biosynthesis JOKFNDED_02698 111105.HR09_09820 8.5e-22 110.5 Porphyromonadaceae hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 ko:K04762,ko:K06179,ko:K06180 ko00000,ko01000,ko03009,ko03110 Bacteria 22Y0I@171551,2FRYM@200643,4NP8I@976,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein JOKFNDED_02700 596151.DesfrDRAFT_3108 9.9e-14 82.0 Desulfovibrionales glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECIAI39_1322.ECIAI39_0637 Bacteria 1MUC8@1224,2M7XR@213115,2WJ5B@28221,42MAX@68525,COG0008@1,COG0008@2 NA|NA|NA J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic JOKFNDED_02701 641524.ADICYQ_5884 2.7e-55 221.9 Cytophagia Bacteria 47UNQ@768503,4NNKV@976,COG3828@1,COG3828@2 NA|NA|NA S Domain of Unknown Function (DUF1080) JOKFNDED_02702 1123257.AUFV01000003_gene873 5.7e-22 110.5 Bacteria glbN GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 ko:K03406,ko:K06886 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria COG2346@1,COG2346@2 NA|NA|NA O COG2346, Truncated hemoglobins JOKFNDED_02703 344747.PM8797T_26105 2.6e-152 546.6 Planctomycetes Bacteria 2IX6X@203682,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2 NA|NA|NA C Membrane-bound dehydrogenase domain protein JOKFNDED_02704 1396141.BATP01000036_gene3839 1.7e-07 62.0 Verrucomicrobiae Bacteria 2IW4D@203494,46VXB@74201,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_02705 926560.KE387027_gene665 2.2e-58 232.6 Deinococcus-Thermus Bacteria 1WJSQ@1297,28JJ5@1,2Z9C9@2 NA|NA|NA S infection protein JOKFNDED_02706 1210884.HG799462_gene8532 2.2e-99 369.4 Planctomycetes Bacteria 2IY8V@203682,COG1520@1,COG1520@2 NA|NA|NA S beta-propeller repeat JOKFNDED_02707 497964.CfE428DRAFT_1107 1.1e-54 219.9 Verrucomicrobia sigW ko:K03088 ko00000,ko03021 Bacteria 46SZG@74201,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family JOKFNDED_02708 886293.Sinac_7155 1.8e-17 96.3 Bacteria pgsAb 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family JOKFNDED_02709 398511.BpOF4_05810 1e-28 133.7 Bacillus 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1UYPW@1239,1ZDI1@1386,4HBVT@91061,COG0860@1,COG0860@2 NA|NA|NA M COG3103 SH3 domain protein JOKFNDED_02711 558884.JRGM01000149_gene3616 7.6e-46 190.7 Aeromonadales sanA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 ko:K03748 ko00000 Bacteria 1MURW@1224,1RMG7@1236,1Y4BW@135624,COG2949@1,COG2949@2 NA|NA|NA S DUF218 domain JOKFNDED_02712 1123070.KB899253_gene1129 9.2e-18 95.9 Verrucomicrobiae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2ITHT@203494,46S9W@74201,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family JOKFNDED_02713 497964.CfE428DRAFT_3441 4.5e-41 174.5 Verrucomicrobia CP_0046 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 46SXX@74201,COG3880@1,COG3880@2 NA|NA|NA S PFAM UvrB UvrC protein JOKFNDED_02716 497964.CfE428DRAFT_0538 3.3e-17 95.1 Bacteria nuoN GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00343,ko:K05573 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iJN678.ndhB Bacteria COG1007@1,COG1007@2 NA|NA|NA C ATP synthesis coupled electron transport JOKFNDED_02717 358220.C380_01340 3.2e-61 242.3 Comamonadaceae Bacteria 1QV5H@1224,2WGPI@28216,4AD4A@80864,COG5001@1,COG5001@2 NA|NA|NA T LapD/MoxY periplasmic domain JOKFNDED_02718 240016.ABIZ01000001_gene462 0.0 2169.0 Verrucomicrobiae 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2ITT7@203494,46TWC@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2,COG3828@1,COG3828@2 NA|NA|NA CEG Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_02719 398767.Glov_0401 3.1e-11 74.7 Deltaproteobacteria dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 1RD08@1224,2WNNA@28221,42RVK@68525,COG1734@1,COG1734@2 NA|NA|NA K Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters JOKFNDED_02721 2340.JV46_05970 6.8e-16 89.7 unclassified Gammaproteobacteria ko:K09794 ko00000 Bacteria 1JBHY@118884,1PJVG@1224,1TB3F@1236,COG2841@1,COG2841@2 NA|NA|NA S Protein of unknown function (DUF465) JOKFNDED_02722 1123242.JH636436_gene23 7.7e-150 537.3 Planctomycetes 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 2IX4V@203682,COG1335@1,COG1335@2,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG3828@1,COG3828@2 NA|NA|NA C COG2133 Glucose sorbosone dehydrogenases JOKFNDED_02723 1396418.BATQ01000091_gene5793 3.1e-86 325.5 Bacteria pepX2 3.4.14.5 ko:K01278,ko:K06889 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity JOKFNDED_02724 530564.Psta_1715 1.8e-123 449.5 Planctomycetes Bacteria 2IX5S@203682,COG3356@1,COG3356@2 NA|NA|NA S Neutral/alkaline non-lysosomal ceramidase, N-terminal JOKFNDED_02725 1123060.JONP01000004_gene527 6.6e-14 83.6 Alphaproteobacteria Bacteria 1N8Y8@1224,2UFKT@28211,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain JOKFNDED_02726 765912.Thimo_0708 1.2e-131 478.0 Chromatiales kefA GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K05802,ko:K06994,ko:K15771,ko:K22051 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3,3.A.1.1.16,3.A.1.1.2 Bacteria 1MWSA@1224,1RMYY@1236,1WXKG@135613,COG1196@1,COG1196@2,COG3264@1,COG3264@2 NA|NA|NA DM mechanosensitive ion channel JOKFNDED_02727 557598.LHK_02307 8.9e-23 112.8 Neisseriales ko:K11312 ko00000 Bacteria 1QUHG@1224,2KS1R@206351,2WGPE@28216,COG0662@1,COG0662@2 NA|NA|NA G Cupin domain JOKFNDED_02728 749414.SBI_00210 8.6e-14 84.3 Actinobacteria 1.13.11.11,2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.30 ko:K00453,ko:K00805,ko:K13787 ko00380,ko00900,ko01100,ko01110,ko01130,map00380,map00900,map01100,map01110,map01130 M00038,M00364,M00365 R00678,R01658,R02003,R02061,R09247 RC00279,RC00356 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IDKH@201174,COG0142@1,COG0142@2 NA|NA|NA H Polyprenyl synthetase JOKFNDED_02729 596152.DesU5LDRAFT_2527 3.6e-14 86.3 Deltaproteobacteria Bacteria 1PIUQ@1224,2WYIV@28221,433FB@68525,COG5653@1,COG5653@2 NA|NA|NA M Acetyltransferase (GNAT) domain JOKFNDED_02730 1454004.AW11_03964 1.6e-297 1028.1 Betaproteobacteria hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,2VK6V@28216,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification JOKFNDED_02732 1123401.JHYQ01000012_gene2822 2.3e-102 379.4 Thiotrichales hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1Q4FB@1224,1RS7D@1236,4615T@72273,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain JOKFNDED_02733 588932.JHOF01000023_gene1893 1e-11 76.3 Alphaproteobacteria ko:K07075,ko:K15773 ko00000,ko02048,ko03000 Bacteria 1N4N3@1224,2UCD9@28211,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins JOKFNDED_02734 595536.ADVE02000001_gene1858 8.2e-105 387.5 Methylocystaceae 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1MVAB@1224,2U1TN@28211,3701H@31993,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain JOKFNDED_02736 365046.Rta_21390 2.5e-110 405.2 Comamonadaceae 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1R5TC@1224,2VHTS@28216,4AEWB@80864,COG0322@1,COG0322@2 NA|NA|NA L Domain of unknown function (DUF4357) JOKFNDED_02737 1123060.JONP01000035_gene3403 3.2e-86 325.5 Alphaproteobacteria Bacteria 1Q97I@1224,2U1AD@28211,COG1479@1,COG1479@2,COG1637@1,COG1637@2 NA|NA|NA L nuclease of the RecB family JOKFNDED_02738 903818.KI912268_gene1974 0.0 1515.0 Acidobacteria hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 3Y3YB@57723,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification JOKFNDED_02740 240016.ABIZ01000001_gene1088 3.8e-40 172.6 Verrucomicrobiae ycgQ ko:K08986 ko00000 Bacteria 2IUV4@203494,46WSH@74201,COG3689@1,COG3689@2 NA|NA|NA S TIGRFAM TIGR03943 family protein JOKFNDED_02741 240016.ABIZ01000001_gene1087 2.7e-68 265.8 Verrucomicrobiae ycgR ko:K07089 ko00000 Bacteria 2IUDU@203494,46V9I@74201,COG0701@1,COG0701@2 NA|NA|NA S Predicted permease JOKFNDED_02742 1396418.BATQ01000016_gene4194 2.6e-35 155.2 Verrucomicrobiae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2IUK4@203494,46VGA@74201,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family JOKFNDED_02743 1396418.BATQ01000004_gene1360 6.3e-74 284.6 Verrucomicrobiae Bacteria 2IV60@203494,46TK9@74201,COG1793@1,COG1793@2 NA|NA|NA L Domain of Unknown Function (DUF1080) JOKFNDED_02744 1403819.BATR01000131_gene4676 9.6e-158 563.5 Verrucomicrobiae 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IUKA@203494,46Z3P@74201,COG1082@1,COG1082@2,COG3386@1,COG3386@2 NA|NA|NA G Arylesterase JOKFNDED_02745 1403819.BATR01000051_gene1494 1.5e-144 520.4 Verrucomicrobiae Bacteria 2IV7T@203494,46SAC@74201,COG1216@1,COG1216@2,COG5309@1,COG5309@2 NA|NA|NA G Glycosyl transferase family 21 JOKFNDED_02746 518766.Rmar_0032 4.9e-26 125.2 Bacteria Bacteria COG0589@1,COG0589@2 NA|NA|NA T AMP binding JOKFNDED_02747 105559.Nwat_1423 8.4e-80 304.3 Gammaproteobacteria Bacteria 1NSQ1@1224,1RMUV@1236,COG4251@1,COG4251@2 NA|NA|NA T Signal transduction histidine kinase JOKFNDED_02748 1242864.D187_001838 6.5e-35 153.7 Myxococcales ko:K02485 ko00000,ko02022 Bacteria 1QUN7@1224,2WP3Z@28221,2Z0F7@29,42T9C@68525,COG0784@1,COG0784@2 NA|NA|NA T cheY-homologous receiver domain JOKFNDED_02749 452637.Oter_0044 2.3e-49 203.4 Verrucomicrobia Bacteria 46VX3@74201,COG0784@1,COG0784@2,COG4585@1,COG4585@2 NA|NA|NA T ATP-binding region ATPase domain protein JOKFNDED_02750 1396418.BATQ01000020_gene5033 1.1e-54 219.9 Verrucomicrobiae mxaB ko:K02282 ko00000,ko02035,ko02044 Bacteria 2IWKX@203494,46SRM@74201,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon JOKFNDED_02751 1396141.BATP01000022_gene256 6.4e-51 208.0 Verrucomicrobiae 3.1.31.1,3.2.2.21 ko:K01174,ko:K07720,ko:K13529,ko:K15051 ko02020,ko03410,map02020,map03410 M00519 ko00000,ko00001,ko00002,ko01000,ko02022,ko03000,ko03400 Bacteria 2IUNB@203494,46UZR@74201,COG2169@1,COG2169@2,COG4936@1,COG4936@2 NA|NA|NA F helix_turn_helix, arabinose operon control protein JOKFNDED_02752 945713.IALB_0431 3.9e-28 132.1 Bacteria 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria COG1102@1,COG1102@2 NA|NA|NA F Psort location Cytoplasmic, score JOKFNDED_02753 240016.ABIZ01000001_gene1413 1.9e-87 329.7 Verrucomicrobia Bacteria 46VTJ@74201,COG3174@1,COG3174@2 NA|NA|NA S Domain of unknown function (DUF4010) JOKFNDED_02754 240016.ABIZ01000001_gene5381 8.1e-16 90.5 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_02755 1121403.AUCV01000012_gene4109 3.1e-14 87.0 Desulfobacterales Bacteria 1QD4I@1224,2MNSY@213118,2X9BC@28221,435MR@68525,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold JOKFNDED_02756 349741.Amuc_0317 4.6e-38 164.5 Verrucomicrobiae recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 ko:K03474,ko:K03584 ko00750,ko01100,ko03440,map00750,map01100,map03440 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IUNX@203494,46VUW@74201,COG1381@1,COG1381@2 NA|NA|NA L Recombination protein O N terminal JOKFNDED_02757 1396418.BATQ01000171_gene2925 3.6e-108 398.3 Verrucomicrobiae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2ITHK@203494,46SAW@74201,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA JOKFNDED_02760 344747.PM8797T_01094 4.6e-125 454.9 Planctomycetes Bacteria 2IYRB@203682,COG1520@1,COG1520@2 NA|NA|NA S beta-propeller repeat JOKFNDED_02761 756272.Plabr_3208 2.9e-162 578.6 Planctomycetes Bacteria 2IXG7@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_02762 1499967.BAYZ01000057_gene4726 6.9e-52 211.1 unclassified Bacteria Bacteria 2NRTI@2323,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_02763 1396141.BATP01000022_gene406 1e-29 136.7 Verrucomicrobiae Bacteria 2IW4C@203494,46VNM@74201,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_02764 530564.Psta_0498 4.2e-239 834.7 Planctomycetes ko:K09992 ko00000 Bacteria 2IXGT@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type JOKFNDED_02765 344747.PM8797T_05420 5.6e-230 803.5 Planctomycetes Bacteria 2IY6R@203682,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity JOKFNDED_02766 290317.Cpha266_0840 3.4e-107 397.1 Chlorobi cyoE ko:K06921 ko00000 Bacteria 1FF2B@1090,COG1357@1,COG1357@2,COG1672@1,COG1672@2,COG2319@1,COG2319@2,COG5635@1,COG5635@2 NA|NA|NA T WD-40 repeat protein JOKFNDED_02767 794903.OPIT5_18900 2.5e-35 155.6 Verrucomicrobia Bacteria 46WHM@74201,COG4185@1,COG4185@2 NA|NA|NA S zeta toxin JOKFNDED_02769 344747.PM8797T_17177 4.4e-93 347.8 Planctomycetes Bacteria 2IY5T@203682,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) JOKFNDED_02770 344747.PM8797T_17182 1.4e-72 280.0 Planctomycetes ptmF 2.7.7.82 ko:K18431 ko00520,map00520 R10182 RC00152 ko00000,ko00001,ko01000 Bacteria 2J0J9@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_02771 314230.DSM3645_18601 3.1e-95 355.1 Planctomycetes 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX60@203682,COG0329@1,COG0329@2 NA|NA|NA EM COG0329 Dihydrodipicolinate synthase N-acetylneuraminate lyase JOKFNDED_02772 240016.ABIZ01000001_gene5314 4.9e-102 377.5 Verrucomicrobiae carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2IU2N@203494,46SBT@74201,COG0458@1,COG0458@2 NA|NA|NA EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain JOKFNDED_02773 1403819.BATR01000054_gene1693 1.4e-16 92.8 Bacteria Bacteria 2DU76@1,33P6T@2 NA|NA|NA JOKFNDED_02774 1173264.KI913949_gene3887 2e-37 163.3 Oscillatoriales Bacteria 1GAA2@1117,1HEDI@1150,COG2339@1,COG2339@2 NA|NA|NA S Protease prsW family JOKFNDED_02775 349741.Amuc_0431 2.1e-130 472.6 Verrucomicrobiae pykF 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2ITNV@203494,46SBJ@74201,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase, barrel domain JOKFNDED_02776 1120988.AXWV01000020_gene1247 4.4e-08 63.5 Aeromonadales VC1707 Bacteria 1NI0B@1224,1SGIA@1236,1Y6AU@135624,2EG1V@1,339TV@2 NA|NA|NA S Domain of unknown function (DUF4250) JOKFNDED_02777 1396418.BATQ01000185_gene2117 1.6e-14 86.7 Verrucomicrobiae Bacteria 2IWN5@203494,46UJT@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG3828@1,COG3828@2 NA|NA|NA C F5/8 type C domain JOKFNDED_02778 1396141.BATP01000058_gene2057 5.7e-79 301.6 Verrucomicrobiae Bacteria 2IW9M@203494,46X07@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_02780 1223523.H340_03214 2e-94 353.2 Actinobacteria Bacteria 2GMA0@201174,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-dependent synthetase and ligase JOKFNDED_02781 1396141.BATP01000060_gene4562 6.4e-64 251.1 Verrucomicrobiae 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVSH@203494,46VXM@74201,COG1716@1,COG1716@2,COG2114@1,COG2114@2 NA|NA|NA T Adenylyl- / guanylyl cyclase, catalytic domain JOKFNDED_02782 313628.LNTAR_17343 1.2e-96 359.8 Bacteria pstB GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria COG1117@1,COG1117@2 NA|NA|NA P ATPase-coupled phosphate ion transmembrane transporter activity JOKFNDED_02783 349741.Amuc_1304 1.4e-87 329.3 Verrucomicrobiae pstA ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2ITN9@203494,46SBK@74201,COG0581@1,COG0581@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component JOKFNDED_02785 388399.SSE37_13653 1e-155 556.2 Alphaproteobacteria fadH 1.3.1.34 ko:K00219 ko00000,ko01000 Bacteria 1MVE0@1224,2TQV0@28211,COG0446@1,COG0446@2,COG1902@1,COG1902@2 NA|NA|NA C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family JOKFNDED_02789 1403819.BATR01000069_gene2092 1.1e-73 283.5 Verrucomicrobiae panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITKC@203494,46SRN@74201,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate JOKFNDED_02790 1403819.BATR01000167_gene5742 1.6e-72 280.0 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_02791 240016.ABIZ01000001_gene1044 9.3e-27 128.3 Verrucomicrobiae Bacteria 2F6YF@1,2IU9D@203494,33ZEH@2,46VWD@74201 NA|NA|NA JOKFNDED_02792 1396418.BATQ01000056_gene159 6.9e-178 631.3 Verrucomicrobiae Bacteria 2IWNR@203494,46TQ1@74201,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Cytochrome c JOKFNDED_02793 1396418.BATQ01000145_gene3535 3.4e-27 127.1 Verrucomicrobia Bacteria 46UQM@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_02796 497964.CfE428DRAFT_6338 1.6e-10 72.8 Verrucomicrobia Bacteria 2FDFS@1,345HD@2,46W4Y@74201 NA|NA|NA JOKFNDED_02797 240016.ABIZ01000001_gene2790 9.7e-40 170.6 Verrucomicrobia Bacteria 2F4CA@1,342S4@2,46VXA@74201 NA|NA|NA JOKFNDED_02798 1123242.JH636434_gene3309 1.7e-86 325.9 Planctomycetes Bacteria 2IWS4@203682,COG1028@1,COG1028@2 NA|NA|NA IQ with different specificities (related to short-chain alcohol JOKFNDED_02799 714943.Mucpa_3660 5.4e-178 630.9 Sphingobacteriia uxaA 3.1.1.17,4.2.1.7 ko:K01053,ko:K01685 ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129,M00631 R01519,R01540,R02933,R03751 RC00537,RC00543,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1INMA@117747,4NFVQ@976,COG2721@1,COG2721@2 NA|NA|NA G PFAM D-galactarate dehydratase Altronate hydrolase JOKFNDED_02800 240016.ABIZ01000001_gene4119 1.6e-27 129.8 Verrucomicrobiae Bacteria 2IUKQ@203494,46WD6@74201,COG0724@1,COG0724@2 NA|NA|NA S RNA recognition motif JOKFNDED_02801 1396141.BATP01000003_gene5131 8.1e-67 260.8 Verrucomicrobiae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2IU70@203494,46T1C@74201,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) JOKFNDED_02802 1396418.BATQ01000058_gene81 9.7e-107 393.7 Verrucomicrobiae aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITYW@203494,46SRE@74201,COG0337@1,COG0337@2 NA|NA|NA E Iron-containing alcohol dehydrogenase JOKFNDED_02803 1396141.BATP01000022_gene309 2e-89 336.3 Verrucomicrobiae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2ITTD@203494,46TMY@74201,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V JOKFNDED_02804 367299.JOEE01000004_gene1013 1.5e-49 202.6 Bacteria ko:K08642 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Bacteria COG0739@1,COG0739@2 NA|NA|NA M heme binding JOKFNDED_02806 313628.LNTAR_01942 1.3e-138 499.2 Bacteria lsrF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 ko:K08321,ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02024,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02024 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria COG1830@1,COG1830@2 NA|NA|NA G lyase activity JOKFNDED_02807 1463841.JOIR01000006_gene4744 4.4e-10 71.2 Actinobacteria ko:K01990,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEU@201174,COG0842@1,COG0842@2,COG1131@1,COG1131@2,COG1716@1,COG1716@2 NA|NA|NA V ABC transporter JOKFNDED_02808 1396141.BATP01000003_gene5119 1.4e-190 672.9 Verrucomicrobiae uup ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2ITVQ@203494,46SJA@74201,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter C-terminal domain JOKFNDED_02809 1519464.HY22_11920 9.5e-46 191.4 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_02810 1268622.AVS7_02480 5.7e-54 218.8 Bacteria ko:K07004 ko00000 Bacteria COG2374@1,COG2374@2,COG3055@1,COG3055@2,COG3391@1,COG3391@2 NA|NA|NA G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses JOKFNDED_02811 344747.PM8797T_20763 1.6e-67 263.5 Planctomycetes Bacteria 2IXCB@203682,COG1331@1,COG1331@2 NA|NA|NA O Pectic acid lyase JOKFNDED_02813 882378.RBRH_03766 8.3e-24 116.7 Burkholderiaceae vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1KA37@119060,1MZB6@1224,2VWH6@28216,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_02814 497964.CfE428DRAFT_3845 5.8e-181 640.6 Verrucomicrobia Bacteria 46SSS@74201,COG4948@1,COG4948@2 NA|NA|NA M Enolase C-terminal domain-like JOKFNDED_02815 1396141.BATP01000030_gene3661 1.1e-111 409.5 Verrucomicrobiae nudF1 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2IU63@203494,46SHC@74201,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain JOKFNDED_02816 1396141.BATP01000030_gene3660 1.8e-230 805.1 Verrucomicrobia pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 46SAG@74201,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP JOKFNDED_02817 1396141.BATP01000030_gene3659 1.5e-73 282.3 Verrucomicrobiae kptA GO:0003674,GO:0003824,GO:0016740,GO:0016772 ko:K07559 ko00000,ko01000,ko03016 Bacteria 2IVR6@203494,46V4P@74201,COG1859@1,COG1859@2 NA|NA|NA J RNA 2'-phosphotransferase, Tpt1 / KptA family JOKFNDED_02818 1396141.BATP01000030_gene3658 6.7e-92 343.6 Verrucomicrobiae Bacteria 2C03A@1,2IVAG@203494,2Z86B@2,46XBC@74201 NA|NA|NA S Domain of unknown function (DUF4291) JOKFNDED_02819 1396141.BATP01000030_gene3657 6e-119 434.1 Verrucomicrobiae Bacteria 2IVNW@203494,46TQN@74201,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase JOKFNDED_02820 452637.Oter_1044 3.4e-42 177.6 Verrucomicrobia Bacteria 46VZX@74201,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase JOKFNDED_02821 1396141.BATP01000030_gene3655 2.4e-65 255.0 Verrucomicrobiae ymdB Bacteria 2IVMR@203494,46SV0@74201,COG2110@1,COG2110@2 NA|NA|NA S Appr-1'-p processing enzyme JOKFNDED_02822 1396141.BATP01000030_gene3654 1.6e-134 485.7 Verrucomicrobiae draG 3.2.2.24 ko:K05521 ko00000,ko01000 Bacteria 2IUJD@203494,46T6X@74201,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase JOKFNDED_02823 1396141.BATP01000030_gene3653 1.5e-93 349.0 Verrucomicrobia pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 46UUK@74201,COG1335@1,COG1335@2 NA|NA|NA Q isochorismatase hydrolase JOKFNDED_02824 1396141.BATP01000030_gene3652 4e-103 380.9 Verrucomicrobiae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 2IUXH@203494,46WEG@74201,COG3201@1,COG3201@2 NA|NA|NA H Nicotinamide mononucleotide transporter JOKFNDED_02825 1396141.BATP01000030_gene3651 4.9e-158 563.9 Verrucomicrobiae nadR Bacteria 2IUZA@203494,46U9K@74201,COG3172@1,COG3172@2 NA|NA|NA H AAA domain JOKFNDED_02826 1038859.AXAU01000011_gene2539 6e-62 245.0 Bradyrhizobiaceae Bacteria 1P9IP@1224,28J0S@1,2TSZQ@28211,2Z8XX@2,3JVZV@41294 NA|NA|NA JOKFNDED_02827 497964.CfE428DRAFT_1982 1.7e-83 316.2 Verrucomicrobia cnpD Bacteria 46U2V@74201,COG0330@1,COG0330@2 NA|NA|NA O PFAM band 7 protein JOKFNDED_02828 1234364.AMSF01000097_gene2635 2.9e-91 342.0 Xanthomonadales nadK 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1NBI3@1224,1RZ58@1236,1X5GX@135614,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP JOKFNDED_02829 1123070.KB899257_gene2329 8.8e-86 323.9 Verrucomicrobiae ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iLJ478.TM1828 Bacteria 2ITYE@203494,46SFQ@74201,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H RibD C-terminal domain JOKFNDED_02830 1123070.KB899254_gene1258 8e-74 285.0 Verrucomicrobiae ko:K11935 ko02026,map02026 ko00000,ko00001 Bacteria 2IV1D@203494,46Z9N@74201,COG4783@1,COG4783@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_02831 1396141.BATP01000003_gene5154 4.7e-32 144.4 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IWJD@203494,46WAM@74201,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor JOKFNDED_02832 240016.ABIZ01000001_gene5925 1.3e-17 96.3 Verrucomicrobiae estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 ko:K12686 ko00000,ko02000,ko02044 1.B.12.8 Bacteria 2IVVJ@203494,46V8N@74201,COG4625@1,COG4625@2 NA|NA|NA U TIGRFAM outer membrane autotransporter barrel domain protein JOKFNDED_02833 756272.Plabr_0744 6.5e-80 304.7 Planctomycetes Bacteria 2IZ88@203682,COG1914@1,COG1914@2 NA|NA|NA P Cytochrome ba3-putative manganese transport protein mntH JOKFNDED_02834 1396141.BATP01000019_gene1585 3.4e-227 794.3 Verrucomicrobiae 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITYU@203494,46S65@74201,COG1171@1,COG1171@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme JOKFNDED_02835 1396141.BATP01000043_gene1930 1.1e-52 213.0 Verrucomicrobiae ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 2IUGR@203494,46X9U@74201,COG1502@1,COG1502@2 NA|NA|NA I Phospholipase D Active site motif JOKFNDED_02836 1396418.BATQ01000156_gene5588 2.4e-189 668.3 Verrucomicrobiae xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038 Bacteria 2ITJ2@203494,46TT2@74201,COG2115@1,COG2115@2 NA|NA|NA G PFAM Xylose isomerase domain protein TIM barrel JOKFNDED_02837 497964.CfE428DRAFT_1687 0.0 1160.2 Verrucomicrobia Bacteria 46TWP@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_02840 1396141.BATP01000007_gene5564 3.9e-93 348.2 Verrucomicrobiae Bacteria 2IVNS@203494,46TZY@74201,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 JOKFNDED_02841 1396141.BATP01000007_gene5565 1.5e-68 266.2 Verrucomicrobiae ko:K03924 ko00000,ko01000 Bacteria 2IVFM@203494,46V0W@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_02842 382464.ABSI01000011_gene2880 1e-14 87.0 Verrucomicrobiae ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IWJ2@203494,46VPT@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_02843 382464.ABSI01000007_gene4063 1.9e-56 226.9 Verrucomicrobiae ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IVTF@203494,46UAW@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_02844 382464.ABSI01000011_gene2882 6e-13 81.6 Verrucomicrobiae Bacteria 2E0WS@1,2IWIE@203494,32WDT@2,46V9V@74201 NA|NA|NA S Protein of unknown function (DUF3450) JOKFNDED_02845 1415780.JPOG01000001_gene2474 5.4e-64 251.9 Xanthomonadales fecA ko:K16091 ko00000,ko02000 1.B.14.1.14 Bacteria 1MWDG@1224,1RQA5@1236,1X5QP@135614,COG4772@1,COG4772@2 NA|NA|NA P receptor JOKFNDED_02846 1396141.BATP01000056_gene3154 2.8e-116 424.9 Verrucomicrobiae rpoD ko:K03086 ko00000,ko03021 Bacteria 2ITQW@203494,46S6M@74201,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth JOKFNDED_02852 1403819.BATR01000049_gene1433 3.5e-233 814.7 Bacteria ko:K02652 ko00000,ko02035,ko02044 3.A.15.2 Bacteria COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB JOKFNDED_02853 452637.Oter_1747 3.8e-19 101.3 Bacteria Bacteria COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_02855 933262.AXAM01000106_gene2632 2.5e-08 66.2 Desulfobacterales Bacteria 1N0AP@1224,28PW7@1,2MKES@213118,2WQ2P@28221,32EDN@2,42UF5@68525 NA|NA|NA S Protein of unknown function (DUF3313) JOKFNDED_02857 983920.Y88_2137 4.3e-128 464.9 Alphaproteobacteria eriC Bacteria 1MV4K@1224,2TTSH@28211,COG0038@1,COG0038@2 NA|NA|NA P Chloride channel JOKFNDED_02858 1396418.BATQ01000056_gene224 3.3e-55 222.2 Bacteria Bacteria COG0583@1,COG0583@2 NA|NA|NA K DNA-binding transcription factor activity JOKFNDED_02859 1403819.BATR01000164_gene5666 1.7e-75 289.7 Verrucomicrobiae apaH 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 2IWDU@203494,46VCP@74201,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase JOKFNDED_02861 349741.Amuc_0198 9.3e-35 152.9 Verrucomicrobiae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUD1@203494,46T0S@74201,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site JOKFNDED_02862 497964.CfE428DRAFT_4619 1.2e-65 257.3 Verrucomicrobia Bacteria 46T1Z@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeats JOKFNDED_02863 1396141.BATP01000020_gene118 2e-149 535.8 Verrucomicrobiae Bacteria 2IVJ6@203494,46SA9@74201,COG1222@1,COG1222@2 NA|NA|NA O ATPase family associated with various cellular activities (AAA) JOKFNDED_02865 563192.HMPREF0179_01446 2.2e-15 90.1 Desulfovibrionales CP_0155 ko:K08307,ko:K12204 ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 1MWKE@1224,2M8IF@213115,2WJ54@28221,42M5C@68525,COG0741@1,COG0741@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM Lytic transglycosylase catalytic JOKFNDED_02866 1403819.BATR01000114_gene3995 1.4e-171 609.4 Verrucomicrobiae ko:K07576 ko00000 Bacteria 2ITNR@203494,46UFS@74201,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain JOKFNDED_02868 1396418.BATQ01000115_gene4612 3.1e-159 568.2 Verrucomicrobiae glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2IUHH@203494,46Z3D@74201,COG0297@1,COG0297@2 NA|NA|NA G Glycosyl transferase 4-like domain JOKFNDED_02869 240016.ABIZ01000001_gene2238 6.3e-96 357.8 Verrucomicrobiae Bacteria 2IWBJ@203494,46TNQ@74201,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase JOKFNDED_02870 1403819.BATR01000104_gene3514 7.3e-108 397.5 Verrucomicrobia Bacteria 46UCY@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_02871 240016.ABIZ01000001_gene2422 1.8e-57 229.9 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_02872 1396141.BATP01000038_gene1199 1.5e-92 346.7 Verrucomicrobiae Bacteria 29D6U@1,2IUVG@203494,3004T@2,46VBG@74201 NA|NA|NA JOKFNDED_02874 909613.UO65_0426 3.8e-78 298.9 Pseudonocardiales 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIT5@201174,4E2AI@85010,COG0019@1,COG0019@2 NA|NA|NA E Pyridoxal-dependent decarboxylase, C-terminal sheet domain JOKFNDED_02875 1396141.BATP01000024_gene812 2.4e-20 105.1 Verrucomicrobiae Bacteria 2AX59@1,2IWFV@203494,31P3N@2,46XRW@74201 NA|NA|NA JOKFNDED_02876 1121098.HMPREF1534_02088 1.6e-08 68.2 Bacteroidaceae epsE ko:K19423 ko00000,ko01000,ko01003 GT2 Bacteria 2FTHH@200643,4AR2N@815,4PKM6@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 JOKFNDED_02878 497964.CfE428DRAFT_2359 8.1e-143 514.6 Verrucomicrobia Bacteria 46U0M@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_02887 460265.Mnod_2069 7.6e-08 65.5 Bacteria XK27_00220 ko:K06999 ko00000 Bacteria COG0400@1,COG0400@2 NA|NA|NA S palmitoyl-(protein) hydrolase activity JOKFNDED_02888 1403819.BATR01000131_gene4674 1.5e-127 463.0 Verrucomicrobiae acoC 2.3.1.12,2.3.1.61 ko:K00627,ko:K00658 ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00307 R00209,R02569,R02570,R02571,R08549 RC00004,RC02727,RC02742,RC02833,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2ITVD@203494,46UHU@74201,COG0508@1,COG0508@2 NA|NA|NA C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) JOKFNDED_02889 1396418.BATQ01000020_gene5039 1.4e-63 249.6 Verrucomicrobiae macB ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2IVNT@203494,46VGE@74201,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_02890 1403819.BATR01000059_gene1814 3.9e-162 578.9 Verrucomicrobiae lolE-2 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVII@203494,46Z4Y@74201,COG4591@1,COG4591@2 NA|NA|NA M FtsX-like permease family JOKFNDED_02891 1396418.BATQ01000020_gene5041 9.4e-97 360.5 Verrucomicrobiae attH Bacteria 2IVAE@203494,46STV@74201,COG5621@1,COG5621@2 NA|NA|NA S Lipocalin-like domain JOKFNDED_02892 1142394.PSMK_03980 1.2e-24 120.9 Bacteria Bacteria 2DBFB@1,2Z8XA@2 NA|NA|NA S Protein of unknown function (DUF4056) JOKFNDED_02893 886293.Sinac_5710 3.2e-258 898.3 Planctomycetes Bacteria 2IXJK@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_02894 1123242.JH636435_gene1859 2e-181 642.1 Planctomycetes Bacteria 2IXQ7@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_02895 1396418.BATQ01000030_gene5617 2.4e-98 365.9 Bacteria Bacteria COG1538@1,COG1538@2 NA|NA|NA MU efflux transmembrane transporter activity JOKFNDED_02896 1403819.BATR01000070_gene2106 1.1e-118 434.1 Verrucomicrobia ko:K02005 ko00000 Bacteria 46WF0@74201,COG0845@1,COG0845@2 NA|NA|NA M HlyD family secretion protein JOKFNDED_02897 240016.ABIZ01000001_gene5156 9.4e-87 326.6 Verrucomicrobiae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IUA4@203494,46SI5@74201,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_02899 1403819.BATR01000118_gene4198 2.1e-73 282.3 Verrucomicrobiae Bacteria 2IUJA@203494,46SSC@74201,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase JOKFNDED_02900 1396418.BATQ01000106_gene5336 2.6e-116 425.6 Verrucomicrobia 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 46SVW@74201,COG1541@1,COG1541@2 NA|NA|NA H AMP-binding enzyme C-terminal domain JOKFNDED_02901 240016.ABIZ01000001_gene3143 1.8e-07 61.6 Verrucomicrobia Bacteria 2EK8J@1,33DYX@2,46VTQ@74201 NA|NA|NA JOKFNDED_02902 1194165.CAJF01000025_gene3302 2.8e-78 298.1 Microbacteriaceae 2.6.1.55 ko:K15372 ko00410,ko00430,ko01100,map00410,map00430,map01100 R00908,R01684 RC00006,RC00062 ko00000,ko00001,ko01000 Bacteria 2I2F3@201174,4FMVE@85023,COG0160@1,COG0160@2 NA|NA|NA E Aminotransferase class-III JOKFNDED_02904 522306.CAP2UW1_2708 9.5e-174 616.3 Betaproteobacteria Z012_01645 Bacteria 1MWKW@1224,2VJ9B@28216,COG3943@1,COG3943@2 NA|NA|NA S Virulence protein RhuM family JOKFNDED_02905 497964.CfE428DRAFT_5227 8.3e-72 277.3 Verrucomicrobia mrr GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 ko:K07448 ko00000,ko02048 Bacteria 46TB1@74201,COG1715@1,COG1715@2 NA|NA|NA L Restriction endonuclease JOKFNDED_02907 1403819.BATR01000164_gene5577 4.6e-278 963.8 Verrucomicrobiae fusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2ITYS@203494,46SFV@74201,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome JOKFNDED_02909 313628.LNTAR_07059 7.7e-171 607.1 Bacteria mdsA Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_02910 1134474.O59_001620 3.8e-110 405.2 Cellvibrio amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1FH32@10,1NR9F@1224,1RNKF@1236,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family JOKFNDED_02912 886293.Sinac_6945 2e-201 708.8 Planctomycetes Bacteria 2IX2H@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_02915 743720.Psefu_4316 4.1e-16 91.7 Gammaproteobacteria Bacteria 1NPV8@1224,1SJGC@1236,COG0398@1,COG0398@2 NA|NA|NA S Pfam SNARE associated Golgi protein JOKFNDED_02917 243090.RB8905 2.8e-111 408.3 Planctomycetes 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2IZ7V@203682,COG1215@1,COG1215@2 NA|NA|NA M COG0463 Glycosyltransferases involved in cell wall JOKFNDED_02919 243090.RB2503 1.4e-90 340.5 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process JOKFNDED_02920 670307.HYPDE_24738 3.6e-75 288.5 Proteobacteria fkbM Bacteria 1R1BC@1224,COG4123@1,COG4123@2 NA|NA|NA S Methyltransferase FkbM domain JOKFNDED_02921 446466.Cfla_3605 2.4e-20 105.9 Actinobacteria fkbM Bacteria 2H027@201174,COG4123@1,COG4123@2 NA|NA|NA S Methyltransferase FkbM domain JOKFNDED_02922 582899.Hden_0450 3.2e-75 288.9 Alphaproteobacteria ko:K00713,ko:K06338 ko00000,ko01000,ko01003,ko01005 Bacteria 1MWSZ@1224,2TQQK@28211,COG0438@1,COG0438@2 NA|NA|NA M PFAM glycosyl transferase group 1 JOKFNDED_02923 243090.RB2485 6.4e-60 238.0 Bacteria gt4D ko:K00786 ko00000,ko01000 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_02924 243090.RB2482 3.4e-89 335.5 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_02925 1217720.ALOX01000057_gene1023 1.1e-44 187.2 Alphaproteobacteria Bacteria 1MZTC@1224,2UE8C@28211,COG2520@1,COG2520@2 NA|NA|NA J Methyltransferase FkbM domain JOKFNDED_02926 1396418.BATQ01000181_gene845 6.9e-105 387.1 Verrucomicrobiae accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 2IU2Q@203494,46SI0@74201,COG0777@1,COG0777@2 NA|NA|NA I Carboxyl transferase domain JOKFNDED_02927 1396141.BATP01000001_gene5286 5.3e-77 294.3 Verrucomicrobiae 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 2IUPE@203494,46STB@74201,COG3786@1,COG3786@2 NA|NA|NA S L,D-transpeptidase catalytic domain JOKFNDED_02928 1040986.ATYO01000013_gene4972 1.7e-09 70.9 Alphaproteobacteria Bacteria 1R3Q7@1224,2UFEG@28211,COG3779@1,COG3779@2 NA|NA|NA S Protein conserved in bacteria JOKFNDED_02929 240016.ABIZ01000001_gene5338 1e-95 357.5 Verrucomicrobiae Bacteria 2EZA2@1,2IV5C@203494,33SFQ@2,46X9V@74201 NA|NA|NA S Transmembrane exosortase (Exosortase_EpsH) JOKFNDED_02930 240016.ABIZ01000001_gene5339 1.5e-80 306.2 Verrucomicrobiae Bacteria 2E96M@1,2IUKS@203494,333F7@2,46X63@74201 NA|NA|NA JOKFNDED_02931 583355.Caka_2945 1.9e-270 938.3 Opitutae tkt GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030312,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Bacteria 3K74F@414999,46SHW@74201,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate JOKFNDED_02932 1396418.BATQ01000008_gene1456 1.3e-118 433.0 Verrucomicrobiae hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITH9@203494,46SHK@74201,COG0040@1,COG0040@2 NA|NA|NA E ATP phosphoribosyltransferase JOKFNDED_02935 1396141.BATP01000027_gene1151 8.1e-101 373.6 Verrucomicrobiae pilH ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2ITWN@203494,46SHV@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_02936 1396141.BATP01000023_gene568 1.7e-20 105.1 Verrucomicrobiae acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 2IUZQ@203494,46W9W@74201,COG1254@1,COG1254@2 NA|NA|NA C Acylphosphatase JOKFNDED_02937 240016.ABIZ01000001_gene326 3e-104 385.2 Verrucomicrobiae ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 2IU0U@203494,46TJB@74201,COG2317@1,COG2317@2 NA|NA|NA E Carboxypeptidase Taq (M32) metallopeptidase JOKFNDED_02938 595460.RRSWK_02341 4.2e-13 81.3 Bacteria 3.5.1.124,4.2.1.103 ko:K03152,ko:K18199 ko00930,map00930 R05771 RC01467 ko00000,ko00001,ko01000,ko01002 Bacteria COG0693@1,COG0693@2 NA|NA|NA S protein deglycation JOKFNDED_02939 1403819.BATR01000163_gene5492 1.9e-66 260.0 Verrucomicrobiae Bacteria 2BYUR@1,2IVA6@203494,32TV8@2,46V5C@74201 NA|NA|NA JOKFNDED_02940 344747.PM8797T_27749 5.3e-206 723.8 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_02941 344747.PM8797T_27754 8.9e-113 414.1 Planctomycetes Bacteria 2IXIG@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_02945 349741.Amuc_2115 1.9e-162 578.9 Verrucomicrobiae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 2ITV1@203494,46S70@74201,COG0172@1,COG0172@2 NA|NA|NA J Seryl-tRNA synthetase N-terminal domain JOKFNDED_02947 240016.ABIZ01000001_gene5836 1.2e-83 317.4 Verrucomicrobia Bacteria 2C4M9@1,342AZ@2,46VU0@74201 NA|NA|NA JOKFNDED_02949 583355.Caka_1112 6.9e-130 470.7 Opitutae sufS 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 3K7QK@414999,46S58@74201,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine JOKFNDED_02951 240016.ABIZ01000001_gene1254 2.1e-53 214.9 Verrucomicrobiae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 2ITTA@203494,46TDX@74201,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthase small chain, CPSase domain JOKFNDED_02952 1223521.BBJX01000001_gene1038 1.5e-12 79.7 Comamonadaceae Bacteria 1MW1M@1224,2VJ1K@28216,4ADC0@80864,COG1716@1,COG1716@2 NA|NA|NA T PFAM Forkhead-associated protein JOKFNDED_02953 497964.CfE428DRAFT_1618 5.3e-141 507.7 Verrucomicrobia purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Bacteria 46TDF@74201,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP JOKFNDED_02954 1396141.BATP01000022_gene199 1e-80 306.6 Verrucomicrobiae uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 iLJ478.TM1398 Bacteria 2IU5V@203494,46SMY@74201,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids JOKFNDED_02957 1031711.RSPO_c02980 7.6e-19 102.4 Burkholderiaceae yajR Bacteria 1K03E@119060,1MVSH@1224,2VITN@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily JOKFNDED_02958 76114.ebB134 1.1e-16 93.6 Proteobacteria Bacteria 1QTR4@1224,2E4RD@1,331HW@2 NA|NA|NA JOKFNDED_02959 1031711.RSPO_c02980 1.3e-11 76.3 Burkholderiaceae yajR Bacteria 1K03E@119060,1MVSH@1224,2VITN@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily JOKFNDED_02960 546267.NEIPOLOT_02541 6.5e-11 75.1 Betaproteobacteria Bacteria 1NJPV@1224,2E4RD@1,2W2WZ@28216,32ZJX@2 NA|NA|NA S Psort location Cytoplasmic, score 8.96 JOKFNDED_02962 1123070.KB899247_gene1650 6.7e-33 147.1 Verrucomicrobiae Bacteria 2IUVB@203494,46Z3R@74201,COG4783@1,COG4783@2 NA|NA|NA S Peptidase family M48 JOKFNDED_02963 242619.PG_1854 2e-15 89.4 Porphyromonadaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 22Y6E@171551,2FQQB@200643,4NQRG@976,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family JOKFNDED_02964 497964.CfE428DRAFT_5297 8.5e-17 94.4 Verrucomicrobia ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 46WAU@74201,COG2608@1,COG2608@2 NA|NA|NA P mercury ion transmembrane transporter activity JOKFNDED_02965 1166018.FAES_2619 1.1e-51 209.9 Cytophagia 3.2.1.4 ko:K01179,ko:K08738 ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R06200,R10151,R11307,R11308 RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.6 GH5,GH9 Bacteria 47JEV@768503,4NEJ0@976,COG2010@1,COG2010@2,COG3291@1,COG3291@2 NA|NA|NA C Domain of Unknown Function (DUF1080) JOKFNDED_02966 338963.Pcar_1022 1.5e-110 406.8 Desulfuromonadales amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1NR9F@1224,2WJE2@28221,42M8M@68525,43S70@69541,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family JOKFNDED_02967 521674.Plim_1549 5.1e-122 444.1 Planctomycetes ko:K07051 ko00000 Bacteria 2IXI8@203682,COG1099@1,COG1099@2 NA|NA|NA S with the TIM-barrel fold JOKFNDED_02968 1305737.JAFX01000001_gene2447 1e-50 207.2 Cytophagia Bacteria 28JEH@1,2Z98N@2,47MQN@768503,4NJHC@976 NA|NA|NA JOKFNDED_02969 243231.GSU2649 1.1e-62 246.9 Deltaproteobacteria glnH ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1RBDN@1224,2X5Z5@28221,43AG9@68525,COG0834@1,COG0834@2 NA|NA|NA ET PFAM Extracellular solute-binding protein, family 3 JOKFNDED_02970 1396141.BATP01000022_gene329 1.3e-24 120.6 Verrucomicrobiae Bacteria 295XR@1,2IWGG@203494,2ZT8M@2,46XS9@74201 NA|NA|NA JOKFNDED_02971 264462.Bd2565 6.2e-23 115.9 Bdellovibrionales ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 1NED3@1224,2MTVC@213481,2WRDH@28221,42WDX@68525,COG3210@1,COG3210@2 NA|NA|NA U cell wall surface anchor family protein JOKFNDED_02972 1396418.BATQ01000127_gene2536 2.5e-22 113.2 Bacteria xerC_3 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family JOKFNDED_02979 466088.CL42_06245 3.9e-12 79.0 Moraxellaceae ko:K07741 ko00000 Bacteria 1N1AT@1224,1RRY7@1236,3NN9E@468,COG3561@1,COG3561@2 NA|NA|NA K AntA/AntB antirepressor JOKFNDED_02981 697281.Mahau_0586 1.3e-06 60.5 Clostridia Bacteria 1VPU7@1239,24VU8@186801,2EFXE@1,339PN@2 NA|NA|NA JOKFNDED_02983 366602.Caul_2923 7.8e-28 131.3 Bacteria ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria COG5632@1,COG5632@2 NA|NA|NA M N-Acetylmuramoyl-L-alanine amidase JOKFNDED_02987 240016.ABIZ01000001_gene3681 1.3e-25 123.6 Verrucomicrobia Bacteria 2F6PM@1,33Z61@2,46VRW@74201 NA|NA|NA S Putative Ig domain JOKFNDED_02989 1403819.BATR01000122_gene4315 1.8e-98 367.5 Verrucomicrobia Bacteria 2DUBH@1,33PTH@2,46U68@74201 NA|NA|NA JOKFNDED_02990 420662.Mpe_A1836 2.3e-42 179.1 Betaproteobacteria Bacteria 1NAAI@1224,2EKAP@1,2VZTN@28216,33E0Y@2 NA|NA|NA JOKFNDED_02996 240016.ABIZ01000001_gene3684 1.2e-25 124.0 Verrucomicrobia Bacteria 2F9YK@1,3427V@2,46VYQ@74201 NA|NA|NA JOKFNDED_02998 1403819.BATR01000122_gene4311 7.4e-18 97.8 Verrucomicrobia Bacteria 2DY75@1,348GC@2,46W2D@74201 NA|NA|NA JOKFNDED_02999 663278.Ethha_0102 5.8e-41 176.0 Ruminococcaceae Bacteria 1TQ28@1239,247QT@186801,3WJR8@541000,COG3941@1,COG3941@2,COG5412@1,COG5412@2 NA|NA|NA D Phage tail tape measure protein, TP901 family JOKFNDED_03002 1007869.M9MUD6_9CAUD 7.2e-20 105.5 Myoviridae Viruses 4QEKM@10239,4QJAG@10662,4QRIU@28883,4QXFJ@35237 NA|NA|NA JOKFNDED_03003 1129374.AJE_03491 1.4e-29 136.3 Proteobacteria Bacteria 1N0DK@1224,COG4122@1,COG4122@2 NA|NA|NA S Methyltransferase domain JOKFNDED_03008 1403819.BATR01000122_gene4307 2.1e-11 75.9 Verrucomicrobia Bacteria 2DF1W@1,2ZQ5Y@2,46WRW@74201 NA|NA|NA JOKFNDED_03012 240016.ABIZ01000001_gene3699 6e-15 87.8 Bacteria Bacteria COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease JOKFNDED_03015 278957.ABEA03000120_gene1193 1.6e-26 127.5 Opitutae Bacteria 2DXQD@1,3460A@2,3KA0J@414999,46V35@74201 NA|NA|NA S P22 coat protein - gene protein 5 JOKFNDED_03017 497964.CfE428DRAFT_1350 2.3e-28 132.9 Verrucomicrobia sppA ko:K04773 ko00000,ko01000,ko01002 Bacteria 46V3T@74201,COG0616@1,COG0616@2 NA|NA|NA OU Peptidase family S49 JOKFNDED_03018 240016.ABIZ01000001_gene3705 6.8e-29 135.6 Verrucomicrobia B Bacteria 46TU8@74201,COG5511@1,COG5511@2 NA|NA|NA S Phage portal protein, lambda family JOKFNDED_03020 240016.ABIZ01000001_gene3708 2.7e-35 157.1 Bacteria Bacteria COG5525@1,COG5525@2 NA|NA|NA S Phage terminase large subunit (GpA) JOKFNDED_03023 240016.ABIZ01000001_gene3711 2.5e-112 412.9 Bacteria ko:K03546 ko00000,ko03400 Bacteria COG1119@1,COG1119@2 NA|NA|NA P ATPase activity JOKFNDED_03024 1235801.C822_00124 1.9e-06 60.5 Lactobacillaceae ko:K07505 ko00000 Bacteria 1TP5Q@1239,3F5W6@33958,4IF7E@91061,COG3598@1,COG3598@2 NA|NA|NA L Primase C terminal 2 (PriCT-2) JOKFNDED_03028 240016.ABIZ01000001_gene3718 7e-54 219.2 Verrucomicrobia ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 46VZP@74201,COG1475@1,COG1475@2 NA|NA|NA K ParB-like nuclease domain JOKFNDED_03031 497964.CfE428DRAFT_1374 1.2e-28 134.4 Bacteria ko:K07497 ko00000 Bacteria COG0582@1,COG0582@2 NA|NA|NA L DNA integration JOKFNDED_03037 1123242.JH636434_gene5524 7.2e-281 973.0 Planctomycetes metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Bacteria 2IXD4@203682,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation JOKFNDED_03038 521674.Plim_3234 8.9e-97 360.5 Planctomycetes Bacteria 2IXVF@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03039 81824.XP_001742167.1 1.1e-72 280.0 Opisthokonta Opisthokonta 39QB5@33154,COG1028@1,KOG1200@2759 NA|NA|NA Q NAD dependent epimerase/dehydratase family JOKFNDED_03040 794903.OPIT5_13610 1.4e-75 290.4 Bacteria Bacteria COG2831@1,COG2831@2 NA|NA|NA U hemolysin activation secretion protein JOKFNDED_03043 794903.OPIT5_08670 1.1e-35 156.8 Opitutae Bacteria 2ARR8@1,30Z2V@2,3K8D5@414999,46W2A@74201 NA|NA|NA JOKFNDED_03044 1396418.BATQ01000167_gene1766 7.7e-22 111.3 Verrucomicrobiae Bacteria 2BTK9@1,2IUYC@203494,32NSZ@2,46X81@74201 NA|NA|NA JOKFNDED_03045 1123070.KB899247_gene1424 1.9e-73 282.0 Verrucomicrobiae Bacteria 2IWHI@203494,46XSU@74201,COG2453@1,COG2453@2 NA|NA|NA T Protein-tyrosine phosphatase JOKFNDED_03046 1304885.AUEY01000096_gene2839 9.2e-107 394.4 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_03047 1123508.JH636447_gene7881 3.1e-65 257.3 Planctomycetes Bacteria 2IXZY@203682,COG0515@1,COG0515@2 NA|NA|NA T COG0515 Serine threonine protein JOKFNDED_03048 1123242.JH636435_gene2613 1.3e-38 166.8 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZZP@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_03049 583355.Caka_2966 9.8e-19 102.1 Opitutae Bacteria 294ZG@1,2ZSCB@2,3K8E5@414999,46WKC@74201 NA|NA|NA JOKFNDED_03050 344747.PM8797T_11766 4.5e-200 704.1 Planctomycetes 3.1.6.13 ko:K01136 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00078 R07812,R07821 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXXP@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_03052 1279017.AQYJ01000026_gene259 1.1e-65 257.3 Bacteria 3.2.1.4 ko:K01179,ko:K03932 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 CE1,GH5,GH9 Bacteria COG3509@1,COG3509@2,COG5297@1,COG5297@2 NA|NA|NA Q xylan catabolic process JOKFNDED_03053 1123242.JH636434_gene5546 7.6e-82 310.5 Planctomycetes Bacteria 2IYVH@203682,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_03054 497964.CfE428DRAFT_3524 1.8e-34 152.9 Bacteria yjjM GO:0005975,GO:0006082,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016052,GO:0016054,GO:0019219,GO:0019222,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0080090,GO:1901575,GO:1903506,GO:2000112,GO:2001141 Bacteria COG1802@1,COG1802@2 NA|NA|NA K Transcriptional regulator JOKFNDED_03055 1403819.BATR01000002_gene74 5.2e-26 124.8 Verrucomicrobiae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1860 Bacteria 2IUIA@203494,46VMG@74201,COG0710@1,COG0710@2 NA|NA|NA E Type I 3-dehydroquinase JOKFNDED_03056 240016.ABIZ01000001_gene1496 7e-111 407.1 Verrucomicrobiae Bacteria 2ITII@203494,46UCT@74201,COG0560@1,COG0560@2 NA|NA|NA E Phosphoserine phosphatase JOKFNDED_03057 266117.Rxyl_0724 6.5e-61 241.1 Rubrobacteria ko:K07071 ko00000 Bacteria 2GJS0@201174,4CQ48@84995,COG1090@1,COG1090@2 NA|NA|NA S Domain of unknown function (DUF1731) JOKFNDED_03059 240016.ABIZ01000001_gene3903 5.1e-33 147.5 Verrucomicrobiae Bacteria 2IW16@203494,46W0N@74201,COG3241@1,COG3241@2 NA|NA|NA C Copper binding proteins, plastocyanin/azurin family JOKFNDED_03061 1173028.ANKO01000017_gene225 9.5e-11 73.9 Oscillatoriales 2.7.13.3,2.7.7.65 ko:K11527,ko:K18967 ko00000,ko01000,ko01001,ko02000,ko02022 9.B.34.1.1 Bacteria 1G09B@1117,1H7M4@1150,COG0642@1,COG0745@1,COG0745@2,COG2202@1,COG2202@2,COG2203@1,COG2203@2,COG2205@2,COG3437@1,COG3437@2,COG5002@1,COG5002@2 NA|NA|NA T PhoQ Sensor JOKFNDED_03062 1403819.BATR01000174_gene5916 2.9e-125 455.3 Verrucomicrobiae Bacteria 2ITIF@203494,46UXT@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel JOKFNDED_03063 1163617.SCD_n00529 9.1e-75 286.6 Betaproteobacteria ydgI ko:K15976 ko00000,ko01000 Bacteria 1RBZQ@1224,2VQTZ@28216,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase JOKFNDED_03064 756272.Plabr_3820 3.5e-143 515.4 Planctomycetes 1.11.1.7,1.6.3.1 ko:K13411,ko:K19511 ko04013,ko04624,map04013,map04624 ko00000,ko00001,ko01000,ko04131 5.B.1.2 Bacteria 2J53M@203682,COG2931@1,COG2931@2 NA|NA|NA C Animal haem peroxidase JOKFNDED_03065 1396418.BATQ01000138_gene3911 7.8e-86 323.6 Bacteria ywqN Bacteria COG0655@1,COG0655@2 NA|NA|NA S NAD(P)H dehydrogenase (quinone) activity JOKFNDED_03066 349741.Amuc_0076 2.8e-43 181.8 Verrucomicrobiae mutT 3.6.1.13,3.6.1.55,3.6.1.56,3.6.1.62,3.6.1.64 ko:K01515,ko:K03574,ko:K16855,ko:K17816 ko00230,ko03018,map00230,map03018 R00961,R01054,R10235,R10815 RC00002 ko00000,ko00001,ko01000,ko03019,ko03400 Bacteria 2IUH7@203494,46VKY@74201,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain JOKFNDED_03069 1396141.BATP01000045_gene1741 2.7e-138 498.0 Verrucomicrobiae menB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 iJN678.menB,iYL1228.KPN_02660 Bacteria 2ITPX@203494,46Z3Z@74201,COG0447@1,COG0447@2 NA|NA|NA H Enoyl-CoA hydratase/isomerase JOKFNDED_03070 357808.RoseRS_0010 1.2e-64 254.2 Chloroflexia Bacteria 2G8T5@200795,376FH@32061,COG0823@1,COG0823@2 NA|NA|NA U WD40-like Beta Propeller Repeat JOKFNDED_03071 1519464.HY22_11920 4.3e-67 262.3 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_03072 1123070.KB899249_gene437 6.5e-35 154.5 Verrucomicrobiae menH 2.2.1.9,4.2.99.20,6.2.1.26 ko:K01911,ko:K02551,ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030,R08165,R08166 RC00004,RC00014,RC02148,RC02186,RC02475 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUN2@203494,46WQX@74201,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family JOKFNDED_03073 240016.ABIZ01000001_gene1324 1.4e-95 357.1 Verrucomicrobiae menD 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITVW@203494,46URH@74201,COG1165@1,COG1165@2 NA|NA|NA H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) JOKFNDED_03074 1396141.BATP01000047_gene3951 3.9e-70 271.9 Verrucomicrobiae menF GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 5.4.4.2 ko:K01851,ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 iYO844.BSU30830 Bacteria 2IU6K@203494,46YW2@74201,COG1169@1,COG1169@2 NA|NA|NA HQ chorismate binding enzyme JOKFNDED_03075 240016.ABIZ01000001_gene3024 1.6e-09 69.7 Verrucomicrobiae Bacteria 2AX49@1,2IWEH@203494,31P2M@2,46XR5@74201 NA|NA|NA JOKFNDED_03076 344747.PM8797T_26845 2.3e-29 136.0 Planctomycetes Bacteria 2DTF7@1,2J3W5@203682,33K38@2 NA|NA|NA JOKFNDED_03077 1403819.BATR01000117_gene4011 0.0 1175.2 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_03079 1396141.BATP01000028_gene2351 3.7e-82 312.0 Verrucomicrobiae avtA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.66 ko:K00835 ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130 R01215 RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 iEKO11_1354.EKO11_0154,iEcSMS35_1347.EcSMS35_3895 Bacteria 2ITU5@203494,46YY9@74201,COG3977@1,COG3977@2 NA|NA|NA E Aminotransferase class I and II JOKFNDED_03080 1396141.BATP01000014_gene2750 5.8e-48 198.0 Verrucomicrobiae thiE 2.5.1.3,2.7.1.49,2.7.4.7 ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU7Q@203494,46SVN@74201,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase JOKFNDED_03081 1403819.BATR01000171_gene5851 2.5e-49 203.0 Verrucomicrobia prc 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 46VYN@74201,COG0793@1,COG0793@2 NA|NA|NA M Peptidase family S41 JOKFNDED_03082 1396141.BATP01000003_gene4885 6.3e-109 401.0 Verrucomicrobiae bioF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iJN678.bioF,iNJ661.Rv1569 Bacteria 2ITJB@203494,46TTU@74201,COG0156@1,COG0156@2 NA|NA|NA H Aminotransferase class I and II JOKFNDED_03083 497964.CfE428DRAFT_5438 2e-73 282.7 Verrucomicrobia Bacteria 46U1I@74201,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold JOKFNDED_03084 756272.Plabr_2400 1.8e-26 126.7 Bacteria Bacteria COG5607@1,COG5607@2 NA|NA|NA F PFAM CHAD domain containing protein JOKFNDED_03085 1123070.KB899270_gene2378 5.5e-53 214.9 Verrucomicrobiae holB 2.7.7.7 ko:K02341,ko:K02343,ko:K09384 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IU8J@203494,46T6T@74201,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III, delta subunit JOKFNDED_03086 497964.CfE428DRAFT_5925 4.2e-54 218.0 Verrucomicrobia tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 46ST1@74201,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis JOKFNDED_03087 756272.Plabr_0159 7.6e-42 176.8 Planctomycetes hisI 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 Bacteria 2J07K@203682,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP JOKFNDED_03088 1403819.BATR01000130_gene4650 2.9e-247 861.3 Verrucomicrobiae Bacteria 2IU45@203494,46TRI@74201,COG1028@1,COG1028@2,COG3347@1,COG3347@2 NA|NA|NA IQ Class II Aldolase and Adducin N-terminal domain JOKFNDED_03089 313624.NSP_17940 2.7e-14 84.0 Nostocales Bacteria 1G71Y@1117,1HQ4Y@1161,COG4634@1,COG4634@2 NA|NA|NA JOKFNDED_03090 278957.ABEA03000095_gene4585 2.5e-14 84.3 Bacteria Bacteria COG2442@1,COG2442@2 NA|NA|NA K InterPro IPR007367 JOKFNDED_03091 158190.SpiGrapes_0372 1.7e-06 60.8 Spirochaetes Bacteria 2JAIV@203691,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03092 1123242.JH636435_gene1179 1.5e-214 752.3 Planctomycetes Bacteria 2IXHT@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_03093 521674.Plim_3398 7.8e-198 696.8 Planctomycetes Bacteria 2IWSZ@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_03094 756272.Plabr_0005 1.8e-64 251.9 Planctomycetes Bacteria 2IY5V@203682,COG3540@1,COG3540@2 NA|NA|NA P PhoD-like phosphatase JOKFNDED_03096 240016.ABIZ01000001_gene1999 2.2e-69 268.9 Verrucomicrobiae hybA ko:K00184 ko00000 5.A.3 Bacteria 2ITQX@203494,46S66@74201,COG0437@1,COG0437@2 NA|NA|NA C 4Fe-4S dicluster domain JOKFNDED_03097 1396418.BATQ01000137_gene3874 2e-197 695.3 Verrucomicrobiae actC ko:K00185 ko00000 5.A.3 Bacteria 2ITK9@203494,46S9S@74201,COG5557@1,COG5557@2 NA|NA|NA C Polysulphide reductase, NrfD JOKFNDED_03098 1396141.BATP01000045_gene1825 1.2e-52 213.0 Verrucomicrobiae Bacteria 2IU5I@203494,46VEQ@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF3341) JOKFNDED_03099 240016.ABIZ01000001_gene2002 1.8e-49 202.6 Verrucomicrobiae actE Bacteria 2IUCS@203494,46SV4@74201,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_03100 1396418.BATQ01000137_gene3871 7.1e-100 371.3 Verrucomicrobiae actF Bacteria 2IWR0@203494,46Z8D@74201,COG5557@1,COG5557@2 NA|NA|NA C Pfam Polysulphide reductase, NrfD JOKFNDED_03102 1403819.BATR01000098_gene3248 4.6e-112 411.8 Verrucomicrobiae 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 Bacteria 2IU2G@203494,46T64@74201,COG3278@1,COG3278@2 NA|NA|NA O Cytochrome C and Quinol oxidase polypeptide I JOKFNDED_03103 1403819.BATR01000098_gene3249 2.7e-29 135.6 Verrucomicrobiae ccoO ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 2IUVC@203494,46YZD@74201,COG2993@1,COG2993@2 NA|NA|NA C Cytochrome C oxidase, mono-heme subunit/FixO JOKFNDED_03104 240016.ABIZ01000001_gene2008 6.6e-27 127.9 Verrucomicrobiae Bacteria 2IVYX@203494,46T74@74201,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_03105 1396141.BATP01000045_gene1832 2.4e-241 841.6 Verrucomicrobiae coxN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2ITKY@203494,46S4Q@74201,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome C and Quinol oxidase polypeptide I JOKFNDED_03106 1133849.O3I_013520 2.3e-18 100.1 Bacteria Bacteria COG1228@1,COG1228@2 NA|NA|NA Q imidazolonepropionase activity JOKFNDED_03109 396588.Tgr7_3090 6.4e-177 627.5 Chromatiales atzF 3.5.1.4,3.5.1.54 ko:K01426,ko:K01457 ko00220,ko00330,ko00360,ko00380,ko00627,ko00643,ko00791,ko01100,ko01120,map00220,map00330,map00360,map00380,map00627,map00643,map00791,map01100,map01120 R00005,R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025,RC02756 ko00000,ko00001,ko01000 Bacteria 1MUVQ@1224,1RR5Z@1236,1WXE4@135613,COG0154@1,COG0154@2 NA|NA|NA J Allophanate hydrolase JOKFNDED_03110 1123070.KB899255_gene1371 2.5e-54 218.8 Verrucomicrobiae Bacteria 2ITXQ@203494,46YZ1@74201,COG3081@1,COG3081@2 NA|NA|NA S 37-kD nucleoid-associated bacterial protein JOKFNDED_03111 886293.Sinac_3224 2.4e-35 157.5 Planctomycetes Bacteria 2IYF2@203682,COG0515@1,COG0515@2 NA|NA|NA KLT COG0515 Serine threonine protein JOKFNDED_03112 1123508.JH636439_gene1312 1.2e-33 150.2 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_03113 344747.PM8797T_22938 6.9e-208 730.7 Planctomycetes Bacteria 2IYEI@203682,COG1073@1,COG1073@2 NA|NA|NA Q alpha beta JOKFNDED_03114 1403819.BATR01000191_gene6490 5.8e-80 304.3 Verrucomicrobiae uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2IURU@203494,46SP6@74201,COG1968@1,COG1968@2 NA|NA|NA V Bacitracin resistance protein BacA JOKFNDED_03115 536019.Mesop_2279 3.5e-97 361.7 Phyllobacteriaceae corA GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 ko:K03284,ko:K16074 ko00000,ko02000 1.A.35.1,1.A.35.3,1.A.35.4 iAF987.Gmet_0134,iYL1228.KPN_04313 Bacteria 1MWMP@1224,2TQQD@28211,43JES@69277,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions JOKFNDED_03116 575540.Isop_2009 1.1e-118 433.7 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_03117 1396141.BATP01000007_gene5672 1.5e-21 109.0 Verrucomicrobiae Bacteria 2IUVH@203494,46W34@74201,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain JOKFNDED_03118 1403819.BATR01000033_gene1101 2e-94 352.8 Verrucomicrobiae nifS GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2IWK9@203494,46SFF@74201,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V JOKFNDED_03119 573370.DMR_01830 1.5e-131 476.5 Desulfovibrionales cls ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1MWUW@1224,2M93H@213115,2WKF2@28221,42PV9@68525,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol JOKFNDED_03120 1122917.KB899659_gene5088 1.1e-20 106.3 Paenibacillaceae Bacteria 1UD16@1239,26ZCD@186822,4HX3U@91061,COG0745@1,COG0745@2 NA|NA|NA T cheY-homologous receiver domain JOKFNDED_03121 240016.ABIZ01000001_gene875 1.7e-119 436.4 Verrucomicrobia Bacteria 46UCM@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_03122 1396418.BATQ01000156_gene5588 1.3e-204 719.2 Verrucomicrobiae xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038 Bacteria 2ITJ2@203494,46TT2@74201,COG2115@1,COG2115@2 NA|NA|NA G PFAM Xylose isomerase domain protein TIM barrel JOKFNDED_03123 1192034.CAP_8096 2.5e-25 122.5 Myxococcales Bacteria 1PC66@1224,2XA3T@28221,2YWAR@29,433UK@68525,COG1994@1,COG1994@2 NA|NA|NA S Peptidase family M50 JOKFNDED_03124 1121403.AUCV01000084_gene3377 6.3e-107 395.6 Deltaproteobacteria Bacteria 1Q712@1224,2WYAY@28221,433SV@68525,COG1305@1,COG1305@2 NA|NA|NA E Domain of Unknown Function with PDB structure (DUF3857) JOKFNDED_03125 1396141.BATP01000057_gene2951 7.9e-50 204.5 Verrucomicrobiae ywaD Bacteria 2IVUM@203494,46VSB@74201,COG2234@1,COG2234@2 NA|NA|NA S Peptidase family M28 JOKFNDED_03126 1396141.BATP01000057_gene2952 4.2e-79 301.6 Verrucomicrobiae parB GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2IU4T@203494,46SQ8@74201,COG1475@1,COG1475@2 NA|NA|NA K ParB-like nuclease domain JOKFNDED_03127 240016.ABIZ01000001_gene5697 2.6e-43 181.4 Verrucomicrobiae ko:K03676,ko:K06191,ko:K07390 ko00000,ko03029,ko03110 Bacteria 2IUDW@203494,46SXS@74201,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin JOKFNDED_03128 240016.ABIZ01000001_gene2761 1.4e-83 317.0 Verrucomicrobiae Bacteria 2IU4X@203494,46UVJ@74201,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase JOKFNDED_03129 240292.Ava_4167 5.7e-23 113.2 Nostocales Bacteria 1G8FX@1117,1HPIE@1161,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) JOKFNDED_03130 1396141.BATP01000006_gene5421 7.7e-159 567.0 Verrucomicrobiae ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2ITP6@203494,46SIU@74201,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY JOKFNDED_03131 1396141.BATP01000027_gene1097 8e-90 337.8 Verrucomicrobiae mgtE ko:K03281,ko:K06213 ko00000,ko02000 1.A.26.1,2.A.49 Bacteria 2IU82@203494,46S6D@74201,COG2239@1,COG2239@2 NA|NA|NA P Divalent cation transporter JOKFNDED_03132 1356852.N008_10720 1.8e-50 206.1 Cytophagia 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183 ko00500,ko00520,ko01100,map00500,map00520,map01100 R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 GH18,GH5,GH9 Bacteria 47QU7@768503,4NMGQ@976,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family JOKFNDED_03133 211165.AJLN01000084_gene1818 1.4e-30 141.0 Stigonemataceae Bacteria 1GFJ1@1117,1JM05@1189,2EMH7@1,33F5U@2 NA|NA|NA JOKFNDED_03135 1249975.JQLP01000005_gene2157 8.8e-31 140.2 Flavobacteriia ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1I2C6@117743,4NMYX@976,COG1487@1,COG1487@2 NA|NA|NA S ribonuclease activity JOKFNDED_03136 1046627.BZARG_2130 3.3e-57 228.8 Flavobacteriia Bacteria 1I04M@117743,28HY7@1,2Z83N@2,4NHX2@976 NA|NA|NA JOKFNDED_03137 56107.Cylst_1387 9.7e-35 153.3 Nostocales Bacteria 1G6CM@1117,1HSAE@1161,29VX9@1,30HF9@2 NA|NA|NA JOKFNDED_03138 272123.Anacy_4469 1.4e-110 406.4 Nostocales Bacteria 1G23E@1117,1HR0X@1161,COG4637@1,COG4637@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system JOKFNDED_03139 1500897.JQNA01000002_gene1901 0.0 2165.6 Burkholderiaceae Bacteria 1K1YE@119060,1MWUJ@1224,2VIQS@28216,COG0286@1,COG0286@2,COG4889@1,COG4889@2 NA|NA|NA L Type III restriction enzyme, res subunit JOKFNDED_03141 240016.ABIZ01000001_gene3279 5.7e-74 283.9 Verrucomicrobiae hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2ITIN@203494,46SFP@74201,COG0079@1,COG0079@2 NA|NA|NA E Aminotransferase class I and II JOKFNDED_03142 1396141.BATP01000058_gene1950 8.6e-15 86.3 Verrucomicrobiae Bacteria 29N4X@1,2IUXE@203494,3092Q@2,46X7T@74201 NA|NA|NA JOKFNDED_03144 886293.Sinac_6486 2.6e-75 290.4 Planctomycetes Bacteria 2IXY4@203682,COG1574@1,COG1574@2 NA|NA|NA Q PFAM amidohydrolase JOKFNDED_03145 1396418.BATQ01000136_gene3697 1.5e-82 312.8 Verrucomicrobiae Bacteria 2IWQZ@203494,46TKJ@74201,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase JOKFNDED_03147 1396418.BATQ01000014_gene4330 2e-216 758.8 Verrucomicrobia Bacteria 46TV6@74201,COG4654@1,COG4654@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_03148 1396418.BATQ01000186_gene2166 2.1e-49 202.6 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_03149 243090.RB8028 9e-68 264.6 Planctomycetes Bacteria 2J0PH@203682,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase JOKFNDED_03150 240016.ABIZ01000001_gene4583 1.7e-78 299.7 Verrucomicrobiae Bacteria 2IWIR@203494,46XTH@74201,COG2885@1,COG2885@2 NA|NA|NA M OmpA family JOKFNDED_03151 243090.RB3006 4.2e-129 468.0 Planctomycetes 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2IWTV@203682,COG0412@1,COG0412@2,COG4409@1,COG4409@2 NA|NA|NA GQ exo-alpha-(2->6)-sialidase activity JOKFNDED_03152 278957.ABEA03000050_gene166 6.2e-28 130.6 Verrucomicrobia Bacteria 2DX9U@1,3441M@2,46WED@74201 NA|NA|NA JOKFNDED_03154 497964.CfE428DRAFT_4340 2.5e-192 679.1 Verrucomicrobia 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 46UNA@74201,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase JOKFNDED_03155 1396418.BATQ01000147_gene3579 3.3e-177 628.6 Verrucomicrobiae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITXG@203494,46TTC@74201,COG1200@1,COG1200@2 NA|NA|NA L RecG wedge domain JOKFNDED_03156 240016.ABIZ01000001_gene2754 3.9e-67 261.9 Verrucomicrobia 2.3.1.241,2.3.1.265 ko:K02517,ko:K20543,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 1.B.55.3 Bacteria 46VIS@74201,COG1560@1,COG1560@2 NA|NA|NA M Bacterial lipid A biosynthesis acyltransferase JOKFNDED_03157 1396418.BATQ01000044_gene6479 6.1e-18 98.2 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_03159 234267.Acid_0104 1.1e-72 281.6 Acidobacteria Bacteria 3Y3RA@57723,COG0457@1,COG0457@2 NA|NA|NA M SMART Tetratricopeptide JOKFNDED_03160 1192034.CAP_8404 1.8e-56 226.9 Bacteria 4.2.2.3 ko:K01729 ko00051,map00051 R03706 ko00000,ko00001,ko01000 Bacteria COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process JOKFNDED_03161 1192034.CAP_6852 1.9e-93 349.7 Proteobacteria Bacteria 1MXUE@1224,2DBH8@1,2Z982@2 NA|NA|NA S Parallel beta-helix repeats JOKFNDED_03162 926550.CLDAP_30780 4.2e-118 431.4 Chloroflexi spoIVFB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K06212,ko:K06402 ko00000,ko01000,ko01002,ko02000 1.A.16.1.1,1.A.16.1.3 Bacteria 2G719@200795,COG0517@1,COG0517@2,COG1994@1,COG1994@2 NA|NA|NA S Belongs to the peptidase M50B family JOKFNDED_03163 497964.CfE428DRAFT_1966 5.1e-145 521.5 Verrucomicrobia Bacteria 46V0M@74201,COG3119@1,COG3119@2 NA|NA|NA P Domain of unknown function JOKFNDED_03164 575540.Isop_3638 6.1e-80 304.7 Planctomycetes Bacteria 2IXQ0@203682,COG1262@1,COG1262@2 NA|NA|NA S PFAM Formylglycine-generating sulfatase enzyme JOKFNDED_03165 497964.CfE428DRAFT_4798 1.9e-167 595.5 Verrucomicrobia Bacteria 46TM4@74201,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase JOKFNDED_03168 1396141.BATP01000023_gene522 3.5e-156 558.1 Verrucomicrobiae MA20_15955 ko:K04096 ko00000 Bacteria 2IVGQ@203494,46XCV@74201,COG4277@1,COG4277@2 NA|NA|NA S Elongator protein 3, MiaB family, Radical SAM JOKFNDED_03169 1396141.BATP01000023_gene521 9e-71 273.9 Verrucomicrobiae 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IVAB@203494,46SWF@74201,COG1573@1,COG1573@2 NA|NA|NA L Domain of unknown function (DUF4130 JOKFNDED_03170 1122222.AXWR01000004_gene1772 3.5e-31 141.4 Deinococcus-Thermus Bacteria 1WMZT@1297,2CVD4@1,32SXD@2 NA|NA|NA JOKFNDED_03171 497964.CfE428DRAFT_5234 1e-34 153.3 Bacteria MA20_01915 Bacteria COG1376@1,COG1376@2 NA|NA|NA D ErfK ybiS ycfS ynhG family protein JOKFNDED_03172 114615.BRADO4752 1e-38 167.5 Bradyrhizobiaceae Bacteria 1QH7T@1224,2U2U0@28211,3K6DP@41294,COG4124@1,COG4124@2 NA|NA|NA G Glycosyl hydrolase family 26 JOKFNDED_03173 1403819.BATR01000147_gene5046 6e-119 434.1 Bacteria ko:K03547 ko00000,ko03400 Bacteria COG0420@1,COG0420@2 NA|NA|NA L 3'-5' exonuclease activity JOKFNDED_03174 1396141.BATP01000058_gene1992 8.9e-103 380.2 Verrucomicrobiae 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2IUAQ@203494,46SRP@74201,COG0657@1,COG0657@2,COG2755@1,COG2755@2 NA|NA|NA I alpha/beta hydrolase fold JOKFNDED_03175 530564.Psta_0517 5.8e-94 350.9 Planctomycetes 3.1.3.1,3.1.4.53 ko:K01077,ko:K03651 ko00230,ko00730,ko00790,ko01100,ko02020,ko02025,map00230,map00730,map00790,map01100,map02020,map02025 M00126 R00191,R02135,R04620 RC00017,RC00296 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2IXAB@203682,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain JOKFNDED_03176 1121430.JMLG01000033_gene1363 2e-14 85.5 Peptococcaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,248W2@186801,260XQ@186807,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs JOKFNDED_03177 1123070.KB899247_gene1622 3.2e-30 138.3 Verrucomicrobiae ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUDV@203494,46T5S@74201,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin JOKFNDED_03178 313628.LNTAR_02152 9.8e-71 273.9 Bacteria hprA 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria COG1052@1,COG1052@2 NA|NA|NA CH NAD binding JOKFNDED_03180 1200557.JHWV01000005_gene1589 8.3e-112 410.6 Negativicutes nirJ ko:K22226 ko00000 Bacteria 1TR85@1239,4H1UM@909932,COG0535@1,COG0535@2 NA|NA|NA C Radical SAM JOKFNDED_03181 1210884.HG799463_gene10120 1.6e-177 629.0 Planctomycetes ykgB 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY02@203682,COG2706@1,COG2706@2 NA|NA|NA G COG2706 3-carboxymuconate cyclase JOKFNDED_03182 1185876.BN8_03562 1.7e-107 396.0 Cytophagia Bacteria 47PP7@768503,4NQ0C@976,COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins JOKFNDED_03183 344747.PM8797T_05265 7.9e-147 526.9 Planctomycetes pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 1.97.1.4 ko:K04069,ko:K06990,ko:K09141 R04710 ko00000,ko01000,ko04812 Bacteria 2IYWA@203682,COG1180@1,COG1180@2,COG1355@1,COG1355@2,COG2078@1,COG2078@2 NA|NA|NA C Radical SAM superfamily JOKFNDED_03184 344747.PM8797T_05265 2e-67 263.5 Planctomycetes pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 1.97.1.4 ko:K04069,ko:K06990,ko:K09141 R04710 ko00000,ko01000,ko04812 Bacteria 2IYWA@203682,COG1180@1,COG1180@2,COG1355@1,COG1355@2,COG2078@1,COG2078@2 NA|NA|NA C Radical SAM superfamily JOKFNDED_03185 1173263.Syn7502_03178 1.5e-40 172.6 Cyanobacteria Bacteria 1G2SE@1117,28KW4@1,2ZACH@2 NA|NA|NA JOKFNDED_03186 1403819.BATR01000065_gene1929 3.2e-12 77.8 Bacteria Bacteria 2CX21@1,32T0Y@2 NA|NA|NA JOKFNDED_03187 240016.ABIZ01000001_gene5591 4.3e-85 321.2 Verrucomicrobia Bacteria 28NEV@1,31YR6@2,46VN6@74201 NA|NA|NA JOKFNDED_03188 1123070.KB899262_gene1689 6.7e-195 688.0 Bacteria Bacteria 2EXP7@1,33QYX@2 NA|NA|NA JOKFNDED_03189 530564.Psta_4426 1.5e-126 459.9 Planctomycetes 3.1.1.101,3.1.1.45 ko:K01061,ko:K21104 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222,R11540 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2J2CS@203682,COG0412@1,COG0412@2 NA|NA|NA Q Acetyl xylan esterase (AXE1) JOKFNDED_03190 1380355.JNIJ01000040_gene5198 0.0 1136.3 Bradyrhizobiaceae Bacteria 1R93M@1224,2UP7I@28211,3K354@41294,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family JOKFNDED_03191 521674.Plim_2370 1.2e-48 201.1 Planctomycetes Bacteria 2IWU5@203682,COG1538@1,COG1538@2 NA|NA|NA MU outer membrane efflux protein JOKFNDED_03192 497964.CfE428DRAFT_4253 4.8e-125 454.9 Verrucomicrobia Bacteria 46URF@74201,COG0523@1,COG0523@2 NA|NA|NA S SRP54-type protein, GTPase domain JOKFNDED_03194 240016.ABIZ01000001_gene971 3.5e-126 458.0 Bacteria rhdA GO:0005575,GO:0005623,GO:0042597,GO:0044464 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 Bacteria COG2897@1,COG2897@2 NA|NA|NA P thiosulfate sulfurtransferase activity JOKFNDED_03195 530564.Psta_3338 7.3e-120 437.2 Planctomycetes cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 2IWWE@203682,COG3049@1,COG3049@2 NA|NA|NA M COG3049 Penicillin V acylase and related JOKFNDED_03196 497964.CfE428DRAFT_3710 2.1e-155 555.4 Verrucomicrobia Bacteria 46TJA@74201,COG1225@1,COG1225@2 NA|NA|NA O Redoxin JOKFNDED_03197 375286.mma_3646 4.5e-70 271.2 Oxalobacteraceae Bacteria 1MUDH@1224,2VRMJ@28216,47632@75682,COG0518@1,COG0518@2 NA|NA|NA F Glutamine amidotransferase class-I JOKFNDED_03198 243231.GSU3125 1.2e-159 569.3 Desulfuromonadales mtd 1.1.1.1 ko:K13953,ko:K13979 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MUTT@1224,2WME2@28221,42MY6@68525,43VHY@69541,COG1064@1,COG1064@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain JOKFNDED_03199 1403819.BATR01000057_gene1774 4e-102 378.3 Verrucomicrobiae 2.1.1.304,2.1.1.327 ko:K21103,ko:K21460 ko00405,ko01130,map00405,map01130 M00835 R11533 RC03466 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVF6@203494,46TY8@74201,COG2519@1,COG2519@2 NA|NA|NA J O-methyltransferase JOKFNDED_03200 1396418.BATQ01000107_gene5398 8.1e-142 510.0 Verrucomicrobiae pdhB 1.2.4.1,1.2.4.4 ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2ITK5@203494,46UID@74201,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain JOKFNDED_03201 344747.PM8797T_00417 2.4e-46 193.0 Planctomycetes 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYTU@203682,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller JOKFNDED_03202 886293.Sinac_2421 6.2e-81 307.8 Planctomycetes Bacteria 2IWZY@203682,COG0673@1,COG0673@2 NA|NA|NA G Oxidoreductase JOKFNDED_03204 1430331.EP10_18160 3.2e-97 362.1 Geobacillus adhB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051704,GO:0071944 1.1.1.1,1.1.1.284 ko:K00001,ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TP8E@1239,1WG1U@129337,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zinc-binding dehydrogenase JOKFNDED_03205 1123070.KB899247_gene1671 2.7e-26 124.8 Verrucomicrobia Bacteria 46W5W@74201,COG5626@1,COG5626@2 NA|NA|NA S Protein of unknown function (DUF2288) JOKFNDED_03206 1185876.BN8_02686 1.5e-23 115.5 Cytophagia glpE Bacteria 47RW1@768503,4NUPH@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain JOKFNDED_03207 344747.PM8797T_27684 0.0 1192.6 Bacteria 3.2.1.11 ko:K05988 ko00500,map00500 R11309 ko00000,ko00001,ko01000 GH66 Bacteria COG1649@1,COG1649@2,COG3525@1,COG3525@2 NA|NA|NA F PFAM Uncharacterised BCR, COG1649 JOKFNDED_03208 344747.PM8797T_24621 2.1e-137 496.9 Planctomycetes Bacteria 2IXWG@203682,COG2010@1,COG2010@2,COG2319@1,COG2319@2 NA|NA|NA C WD-40 repeat JOKFNDED_03209 555779.Dthio_PD1484 6.1e-08 63.5 Bacteria Bacteria COG3668@1,COG3668@2 NA|NA|NA D Plasmid stabilization system JOKFNDED_03211 344747.PM8797T_24626 8.4e-252 876.7 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IXIZ@203682,COG5492@1,COG5492@2 NA|NA|NA N Bacterial Ig-like domain (group 2) JOKFNDED_03212 344747.PM8797T_24631 3.5e-38 164.1 Planctomycetes Bacteria 2IXN7@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03213 595460.RRSWK_00611 1.5e-215 756.1 Planctomycetes 3.1.1.53 ko:K05970 ko00000,ko01000 Bacteria 2IWTR@203682,COG2755@1,COG2755@2 NA|NA|NA E sialic acid-specific 9-O-acetylesterase JOKFNDED_03214 1403819.BATR01000126_gene4509 2.2e-97 362.8 Bacteria 4.2.2.3 ko:K01729 ko00051,map00051 R03706 ko00000,ko00001,ko01000 Bacteria COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process JOKFNDED_03215 344747.PM8797T_28454 7.1e-53 213.4 Planctomycetes tdcF2 Bacteria 2IZC0@203682,COG0251@1,COG0251@2 NA|NA|NA J YjgF/chorismate_mutase-like, putative endoribonuclease JOKFNDED_03217 756272.Plabr_3000 0.0 1348.2 Planctomycetes Bacteria 2IXJ6@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_03219 756272.Plabr_2999 6.4e-215 753.4 Planctomycetes Bacteria 2IX1H@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_03220 240016.ABIZ01000001_gene379 3.8e-09 70.1 Bacteria 3.1.3.8 ko:K01083,ko:K02519 ko00562,map00562 R03371 RC00078 ko00000,ko00001,ko01000,ko03012,ko03029 Bacteria COG5164@1,COG5164@2 NA|NA|NA K cell wall organization JOKFNDED_03221 1403819.BATR01000017_gene562 1.5e-99 369.8 Verrucomicrobiae ko:K02529 ko00000,ko03000 Bacteria 2IUF7@203494,46U1N@74201,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain JOKFNDED_03222 1396418.BATQ01000058_gene90 9e-99 366.7 Verrucomicrobia MA20_26380 Bacteria 46SB3@74201,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA JOKFNDED_03223 314230.DSM3645_18666 9.8e-79 300.1 Planctomycetes Bacteria 2J0HN@203682,COG5285@1,COG5285@2 NA|NA|NA Q COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin JOKFNDED_03224 331678.Cphamn1_0337 3.1e-46 191.8 Chlorobi hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1FEZT@1090,COG0610@1,COG0610@2,COG1943@1,COG1943@2 NA|NA|NA LV Subunit R is required for both nuclease and ATPase activities, but not for modification JOKFNDED_03225 344747.PM8797T_22928 2.9e-115 422.2 Planctomycetes Bacteria 2C9Z0@1,2J3JA@203682,2ZBDC@2 NA|NA|NA S Parallel beta-helix repeats JOKFNDED_03226 344747.PM8797T_09059 6e-106 391.3 Bacteria Bacteria COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family JOKFNDED_03227 344747.PM8797T_27150 5.2e-113 414.5 Planctomycetes 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2J4T9@203682,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_03228 344747.PM8797T_17187 4.4e-174 617.8 Planctomycetes Bacteria 2IY26@203682,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity JOKFNDED_03229 497964.CfE428DRAFT_4719 9.5e-178 630.2 Bacteria Bacteria COG5301@1,COG5301@2 NA|NA|NA G cellulose 1,4-beta-cellobiosidase activity JOKFNDED_03230 1403819.BATR01000018_gene577 2.4e-145 521.9 Verrucomicrobiae 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2IVXN@203494,46SCF@74201,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_03233 344747.PM8797T_22933 1.3e-221 775.8 Planctomycetes Bacteria 2J36G@203682,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity JOKFNDED_03234 452637.Oter_1248 2e-10 71.6 Opitutae vapC ko:K07064 ko00000 Bacteria 3K8HY@414999,46XWY@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_03235 452637.Oter_1247 6.9e-08 63.2 Opitutae GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 Bacteria 3K8HF@414999,46XWT@74201,COG4118@1,COG4118@2 NA|NA|NA D positive regulation of growth JOKFNDED_03236 344747.PM8797T_20918 6.6e-246 857.1 Planctomycetes hemL 5.4.3.8 ko:K01845,ko:K07100,ko:K07257,ko:K15681 ko00860,ko01053,ko01100,ko01110,ko01120,map00860,map01053,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007,ko01008 Bacteria 2IZE0@203682,COG0001@1,COG0001@2,COG3618@1,COG3618@2 NA|NA|NA H Aminotransferase class-III JOKFNDED_03237 240016.ABIZ01000001_gene3859 1.8e-12 77.8 Verrucomicrobiae Bacteria 2ITSE@203494,46SNA@74201,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain JOKFNDED_03238 497964.CfE428DRAFT_5918 8.5e-45 187.2 Verrucomicrobia pgl 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 46T8I@74201,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase JOKFNDED_03239 1303518.CCALI_02067 8.9e-82 310.5 Bacteria ko:K03830 ko00000,ko01000 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase JOKFNDED_03240 240016.ABIZ01000001_gene4741 4.4e-21 108.2 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_03248 1396418.BATQ01000044_gene6479 1e-17 97.4 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_03249 382464.ABSI01000005_gene1056 1.5e-39 169.1 Verrucomicrobiae Bacteria 2ITQR@203494,46UZ1@74201,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain JOKFNDED_03250 251221.35213566 2.9e-81 309.7 Cyanobacteria 3.2.1.4 ko:K01179,ko:K20276 ko00500,ko01100,ko02024,map00500,map01100,map02024 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1G72X@1117,COG1404@1,COG1404@2,COG5549@1,COG5549@2 NA|NA|NA O cellulose binding JOKFNDED_03251 1396418.BATQ01000168_gene1825 7.5e-229 799.7 Verrucomicrobiae sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 ko:K07033,ko:K09014 ko00000 iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 Bacteria 2IU30@203494,46SGN@74201,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) JOKFNDED_03252 240016.ABIZ01000001_gene997 1.4e-101 375.9 Verrucomicrobiae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 2ITY7@203494,46SGE@74201,COG0396@1,COG0396@2 NA|NA|NA O ATPases associated with a variety of cellular activities JOKFNDED_03253 240016.ABIZ01000001_gene998 1.3e-28 132.9 Verrucomicrobiae perR ko:K03711,ko:K09825,ko:K22297 ko00000,ko03000 Bacteria 2IUJS@203494,46W8N@74201,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family JOKFNDED_03254 1403819.BATR01000092_gene2711 6.6e-114 417.2 Verrucomicrobiae Bacteria 2DBN7@1,2IU5M@203494,2ZA2Y@2,46TTS@74201 NA|NA|NA S Domain of unknown function (DUF4159) JOKFNDED_03255 497964.CfE428DRAFT_4596 7.9e-08 64.7 Bacteria ko:K02283,ko:K02454,ko:K03220,ko:K03466 ko03070,ko05111,map03070,map05111 M00331,M00332 ko00000,ko00001,ko00002,ko02035,ko02044,ko03036 3.A.12,3.A.15,3.A.6.1 Bacteria COG0745@1,COG0745@2,COG1716@1,COG1716@2 NA|NA|NA T histone H2A K63-linked ubiquitination JOKFNDED_03256 1123070.KB899253_gene1063 3.9e-26 125.6 Verrucomicrobia pldB GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049 Bacteria 46WYY@74201,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 JOKFNDED_03259 521674.Plim_0374 9.6e-79 301.6 Bacteria Bacteria COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase JOKFNDED_03261 1396418.BATQ01000163_gene1976 1.1e-80 308.1 Verrucomicrobiae ko:K07403 ko00000 Bacteria 2IU3S@203494,46TAS@74201,COG1030@1,COG1030@2 NA|NA|NA JOKFNDED_03264 497964.CfE428DRAFT_0520 1.4e-13 82.8 Verrucomicrobia Bacteria 46WDF@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_03266 62928.azo2525 5.6e-124 451.4 Betaproteobacteria Bacteria 1Q0E0@1224,29WH2@1,2W579@28216,30I35@2 NA|NA|NA JOKFNDED_03267 1396141.BATP01000057_gene2988 1.1e-74 287.0 Verrucomicrobiae nrnA GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 ko:K00974,ko:K06881 ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013 R00188,R00508,R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 2ITUW@203494,46T03@74201,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain JOKFNDED_03269 1403819.BATR01000092_gene2723 8.2e-87 328.6 Verrucomicrobiae Bacteria 2IU8M@203494,46UJD@74201,COG0457@1,COG0457@2,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03270 1403819.BATR01000154_gene5147 4.1e-33 148.7 Verrucomicrobiae Bacteria 2FEQM@1,2IUQQ@203494,346PU@2,46W7F@74201 NA|NA|NA JOKFNDED_03272 240016.ABIZ01000001_gene3614 1.4e-193 682.9 Verrucomicrobiae mutL GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 2ITR4@203494,46SG5@74201,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex JOKFNDED_03273 595460.RRSWK_01904 2.1e-205 721.8 Planctomycetes 3.10.1.1 ko:K01565 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00078 R07814 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX47@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_03274 595537.Varpa_3681 3.9e-75 288.5 Comamonadaceae Bacteria 1R7GE@1224,28JZ9@1,2VRNV@28216,2Z9PC@2,4AE9R@80864 NA|NA|NA JOKFNDED_03275 756272.Plabr_4221 6e-14 82.4 Planctomycetes Bacteria 2IXXZ@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_03276 1123242.JH636434_gene5546 2.9e-73 282.0 Planctomycetes Bacteria 2IYVH@203682,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_03277 574087.Acear_1823 3.8e-22 111.7 Halanaerobiales fxsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 ko:K07113 ko00000 Bacteria 1VF5Y@1239,24NG5@186801,3WBVZ@53433,COG3030@1,COG3030@2 NA|NA|NA S PFAM FxsA cytoplasmic membrane protein JOKFNDED_03279 1396141.BATP01000003_gene4876 3.9e-100 371.7 Verrucomicrobiae hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2ITVN@203494,46STN@74201,COG0635@1,COG0635@2 NA|NA|NA H Elongator protein 3, MiaB family, Radical SAM JOKFNDED_03280 1123290.AUDQ01000014_gene1134 2.7e-13 82.0 Planococcaceae yqeZ ko:K07403 ko00000 Bacteria 1TR54@1239,26CYG@186818,4H9P9@91061,COG1030@1,COG1030@2 NA|NA|NA O NfeD-like C-terminal, partner-binding JOKFNDED_03281 1403819.BATR01000104_gene3519 0.0 1198.3 Verrucomicrobiae secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2ITJP@203494,46SJC@74201,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane JOKFNDED_03282 497964.CfE428DRAFT_5497 7.8e-79 300.4 Verrucomicrobia soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 46SKQ@74201,COG1192@1,COG1192@2 NA|NA|NA D PFAM Cobyrinic acid ac-diamide synthase JOKFNDED_03283 1509405.GV67_00790 2.5e-14 86.3 Rhizobiaceae Bacteria 1MXPY@1224,2TUBP@28211,4B77J@82115,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) JOKFNDED_03284 497964.CfE428DRAFT_4279 2.5e-160 572.0 Verrucomicrobia mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 46THM@74201,COG0773@1,COG0773@2 NA|NA|NA M Mur ligase middle domain protein JOKFNDED_03285 497964.CfE428DRAFT_6160 1.1e-64 253.1 Verrucomicrobia Bacteria 46TTE@74201,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain JOKFNDED_03287 1396418.BATQ01000138_gene3939 2.2e-305 1054.7 Verrucomicrobiae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 2IUEK@203494,46S8Y@74201,COG0046@1,COG0046@2 NA|NA|NA F involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate JOKFNDED_03288 1403819.BATR01000096_gene3182 1.7e-33 149.1 Verrucomicrobiae Bacteria 2AWY0@1,2IW6B@203494,31NVN@2,46XM4@74201 NA|NA|NA JOKFNDED_03289 240016.ABIZ01000001_gene1936 9.2e-117 427.2 Bacteria purC 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria COG0152@1,COG0152@2 NA|NA|NA F phosphoribosylaminoimidazolesuccinocarboxamide synthase activity JOKFNDED_03290 1541065.JRFE01000024_gene811 1.4e-65 256.9 Pleurocapsales ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1G36J@1117,3VIEX@52604,COG0834@1,COG0834@2 NA|NA|NA ET Ligand-gated ion channel JOKFNDED_03291 1289135.A966_11661 2.1e-85 322.8 Bacteria 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 GH32 Bacteria COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family JOKFNDED_03292 1123242.JH636435_gene1030 3.1e-57 228.8 Planctomycetes Bacteria 2IZHD@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_03293 1123401.JHYQ01000014_gene879 1.9e-38 166.4 Gammaproteobacteria ko:K07098 ko00000 Bacteria 1MUH5@1224,1RZ45@1236,COG1408@1,COG1408@2 NA|NA|NA S Metallophosphoesterase JOKFNDED_03295 1123401.JHYQ01000001_gene1725 1.4e-18 99.8 Gammaproteobacteria Bacteria 1RBUG@1224,1SVAY@1236,2DZKR@1,32VDB@2 NA|NA|NA JOKFNDED_03296 1173024.KI912152_gene717 4.9e-24 118.6 Bacteria Bacteria 2E5MT@1,330CP@2 NA|NA|NA JOKFNDED_03298 1403819.BATR01000104_gene3623 1.1e-118 433.3 Verrucomicrobia 1.1.99.28 ko:K00118 ko00000,ko01000 Bacteria 46UTZ@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03299 756272.Plabr_0617 5.7e-46 190.7 Planctomycetes yegT ko:K03301,ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25,2.A.12 Bacteria 2IWTX@203682,COG2211@1,COG2211@2 NA|NA|NA G MFS_1 like family JOKFNDED_03300 547045.NEISICOT_01680 2.3e-17 95.9 Bacteria Bacteria 2C0JR@1,34BSC@2 NA|NA|NA JOKFNDED_03301 1385935.N836_02890 4.7e-30 138.3 Bacteria ywaF Bacteria COG5522@1,COG5522@2 NA|NA|NA S Integral membrane protein (intg_mem_TP0381) JOKFNDED_03302 794903.OPIT5_09940 3.2e-30 139.0 Opitutae ko:K07506 ko00000,ko03000 Bacteria 3K9WC@414999,46W5E@74201,COG4977@1,COG4977@2 NA|NA|NA K PFAM helix-turn-helix- domain containing protein AraC type JOKFNDED_03303 497964.CfE428DRAFT_1453 2.4e-153 549.3 Verrucomicrobia mtgA GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K03693,ko:K03814,ko:K04478,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K18770,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 iAF987.Gmet_1671 Bacteria 46U6K@74201,COG0744@1,COG0744@2 NA|NA|NA M PFAM glycosyl transferase family 51 JOKFNDED_03305 1123070.KB899256_gene2182 6.2e-14 83.6 Verrucomicrobiae Bacteria 2DKJX@1,2IV07@203494,309RR@2,46ZIG@74201 NA|NA|NA S Putative prokaryotic signal transducing protein JOKFNDED_03306 314230.DSM3645_12931 1.5e-61 243.4 Planctomycetes dfrA 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 2IYXE@203682,COG0451@1,COG0451@2 NA|NA|NA GM PFAM NAD dependent epimerase dehydratase family JOKFNDED_03307 595460.RRSWK_07171 8.2e-239 833.9 Planctomycetes rkpG 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IXBN@203682,COG0156@1,COG0156@2,COG0318@1,COG0318@2 NA|NA|NA IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases JOKFNDED_03308 443143.GM18_2751 3.6e-64 252.3 Deltaproteobacteria Bacteria 1PMA3@1224,2WKSE@28221,42PYX@68525,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase JOKFNDED_03309 91464.S7335_5357 3.9e-45 189.1 Synechococcus Bacteria 1G3WZ@1117,1GZ5P@1129,2BWJ3@1,2Z7IQ@2 NA|NA|NA S Sulfotransferase family JOKFNDED_03311 595460.RRSWK_01975 1.9e-142 513.1 Bacteria wcbR Bacteria COG3321@1,COG3321@2 NA|NA|NA Q synthase JOKFNDED_03312 118173.KB235914_gene768 1.5e-67 262.3 Oscillatoriales Bacteria 1G7A6@1117,1HDSQ@1150,COG4675@1,COG4675@2 NA|NA|NA S Phage Tail Collar Domain JOKFNDED_03314 1230476.C207_03994 4.7e-38 164.5 Bradyrhizobiaceae Bacteria 1N29T@1224,2UF3Q@28211,3JYMP@41294,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein JOKFNDED_03315 926560.KE387023_gene1193 2.4e-07 61.2 Bacteria Bacteria 2EJ72@1,33CY7@2 NA|NA|NA JOKFNDED_03316 314230.DSM3645_17285 6e-164 583.9 Planctomycetes Bacteria 2IYMG@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_03317 314230.DSM3645_17290 2.3e-46 191.8 Planctomycetes Bacteria 2IWU7@203682,COG1020@1,COG1020@2,COG2010@1,COG2010@2 NA|NA|NA Q Protein of unknown function (DUF1587) JOKFNDED_03318 575540.Isop_3616 5.5e-135 488.0 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_03320 1040982.AXAL01000022_gene6470 8.1e-09 65.5 Phyllobacteriaceae soxA 1.5.3.1,1.5.99.5,2.1.2.10 ko:K00302,ko:K00605,ko:K22086 ko00260,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200 M00532 R00609,R00610,R01221,R02300,R04125 RC00022,RC00060,RC00069,RC00183,RC00190,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVEK@1224,2TTD7@28211,43HN3@69277,COG0404@1,COG0404@2,COG0446@1,COG0446@2 NA|NA|NA E Belongs to the GcvT family JOKFNDED_03321 240016.ABIZ01000001_gene5655 2.7e-163 581.6 Verrucomicrobiae dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 Bacteria 2ITIS@203494,46SAU@74201,COG1154@1,COG1154@2 NA|NA|NA HI Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) JOKFNDED_03323 272134.KB731324_gene3229 2.5e-58 233.4 Cyanobacteria 2.7.13.3 ko:K07636,ko:K07645 ko02020,ko02024,map02020,map02024 M00434,M00453 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1GQDS@1117,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JOKFNDED_03324 382464.ABSI01000007_gene4118 1.6e-79 302.8 Verrucomicrobiae Bacteria 2IUEX@203494,46TFB@74201,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_03325 671143.DAMO_1661 1.5e-43 185.3 Bacteria mauG GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 ko:K00428 ko00000,ko01000 Bacteria COG1858@1,COG1858@2 NA|NA|NA C electron transfer activity JOKFNDED_03326 504472.Slin_2978 3.6e-119 434.9 Bacteria ytaP Bacteria COG1073@1,COG1073@2 NA|NA|NA S thiolester hydrolase activity JOKFNDED_03327 497964.CfE428DRAFT_5599 1.9e-29 135.6 Bacteria vapC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07064 ko00000 Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_03329 1396418.BATQ01000179_gene3137 1.9e-35 157.5 Bacteria 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria COG0652@1,COG0652@2,COG4733@1,COG4733@2 NA|NA|NA S cellulase activity JOKFNDED_03330 1128421.JAGA01000001_gene2004 2.4e-208 732.3 unclassified Bacteria glgX 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2NPQU@2323,COG1523@1,COG1523@2 NA|NA|NA G Carbohydrate-binding module 48 (Isoamylase N-terminal domain) JOKFNDED_03331 1396141.BATP01000039_gene1246 3.6e-61 241.9 Verrucomicrobiae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVP9@203494,46V4C@74201,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein JOKFNDED_03332 32057.KB217478_gene1041 6.6e-16 90.1 Nostocales ko:K07171 ko00000,ko01000,ko02048 Bacteria 1G72T@1117,1HSMF@1161,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system JOKFNDED_03334 382464.ABSI01000020_gene232 3.6e-137 495.4 Verrucomicrobiae oppA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667 Bacteria 2IWMV@203494,46TR7@74201,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle JOKFNDED_03335 382464.ABSI01000020_gene230 9.1e-82 310.5 Verrucomicrobiae oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2ITJ0@203494,46SJN@74201,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component JOKFNDED_03336 1121374.KB891587_gene3001 2.4e-85 322.4 Gammaproteobacteria oppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021 Bacteria 1MU26@1224,1RND6@1236,COG1173@1,COG1173@2 NA|NA|NA P COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components JOKFNDED_03337 1123070.KB899269_gene2382 7.1e-65 253.8 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IU42@203494,46VJP@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_03338 1396141.BATP01000038_gene1227 2.8e-25 122.9 Verrucomicrobiae ko:K04033 ko00000,ko03000 Bacteria 2IWIS@203494,46WKZ@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_03339 1403819.BATR01000009_gene302 1.1e-208 732.6 Verrucomicrobiae 3.1.6.12 ko:K01135 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 2IVET@203494,46TNU@74201,COG3119@1,COG3119@2 NA|NA|NA P Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_03340 383372.Rcas_0520 1.3e-99 370.2 Bacteria Bacteria COG0673@1,COG0673@2 NA|NA|NA S inositol 2-dehydrogenase activity JOKFNDED_03341 344747.PM8797T_19031 3.1e-80 305.4 Planctomycetes Bacteria 2J0ZB@203682,COG0673@1,COG0673@2 NA|NA|NA S and related JOKFNDED_03342 240016.ABIZ01000001_gene92 1.4e-49 203.8 Verrucomicrobiae lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2ITQF@203494,46SAD@74201,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell JOKFNDED_03343 1396418.BATQ01000152_gene2403 5.6e-08 64.7 Verrucomicrobiae ompH ko:K06142 ko00000 Bacteria 2IUS2@203494,46T22@74201,COG2825@1,COG2825@2 NA|NA|NA M Outer membrane protein (OmpH-like) JOKFNDED_03344 240016.ABIZ01000001_gene1278 6.8e-171 607.8 Verrucomicrobiae yaeT ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 2ITS5@203494,46S5F@74201,COG4775@1,COG4775@2 NA|NA|NA M Surface antigen JOKFNDED_03346 595460.RRSWK_01778 8.8e-185 653.3 Planctomycetes pykF 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2IY60@203682,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family JOKFNDED_03347 240016.ABIZ01000001_gene5214 4.5e-68 265.0 Verrucomicrobiae rmlA GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 ko:K00966,ko:K00973,ko:K00992 ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130 M00114,M00361,M00362,M00793 R00885,R02328,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU9T@203494,46SJP@74201,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase JOKFNDED_03348 1396141.BATP01000019_gene1577 7.5e-59 233.8 Verrucomicrobiae rex GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K01926 ko00000,ko03000 Bacteria 2IU8U@203494,46V46@74201,COG2344@1,COG2344@2 NA|NA|NA K Putative DNA-binding protein N-terminus JOKFNDED_03349 497964.CfE428DRAFT_1494 1.4e-71 276.2 Verrucomicrobia acuC Bacteria 46SMT@74201,COG0123@1,COG0123@2 NA|NA|NA BQ Histone deacetylase domain JOKFNDED_03350 1430440.MGMSRv2_3763 3.3e-168 599.0 Rhodospirillales XK27_08510 Bacteria 1QVE4@1224,2JW67@204441,2TUH9@28211,COG1061@1,COG1061@2,COG4951@1,COG4951@2 NA|NA|NA L DEAD-like helicases superfamily JOKFNDED_03352 449447.MAE_19200 4e-233 815.1 Cyanobacteria 2.1.1.72 ko:K00571,ko:K07317 ko00000,ko01000,ko02048 Bacteria 1G3V8@1117,COG0827@1,COG0827@2,COG1002@1,COG1002@2 NA|NA|NA V type I restriction-modification system JOKFNDED_03353 1396141.BATP01000003_gene4887 1.7e-28 132.9 Verrucomicrobiae umuD2 3.4.21.88 ko:K01356,ko:K03503 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2IU8D@203494,46SU8@74201,COG1974@1,COG1974@2 NA|NA|NA KT LexA DNA binding domain JOKFNDED_03354 1123278.KB893546_gene5001 1.7e-275 954.9 Cytophagia Bacteria 47JQ2@768503,4NEF2@976,COG2303@1,COG2303@2 NA|NA|NA E PFAM glucose-methanol-choline oxidoreductase JOKFNDED_03355 497964.CfE428DRAFT_4623 5.5e-55 220.7 Verrucomicrobia Bacteria 2CDAN@1,314BB@2,46WI7@74201 NA|NA|NA S Gluconate 2-dehydrogenase subunit 3 JOKFNDED_03356 760192.Halhy_1904 4.3e-86 326.2 Sphingobacteriia Bacteria 1IPX3@117747,4NKS7@976,COG3751@1,COG3751@2 NA|NA|NA O 2OG-Fe(II) oxygenase superfamily JOKFNDED_03357 323098.Nwi_2868 2.6e-148 531.9 Bradyrhizobiaceae 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1N458@1224,2TVQF@28211,3JXF2@41294,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain JOKFNDED_03358 1121033.AUCF01000029_gene320 2.1e-31 141.7 Alphaproteobacteria ko:K15539 ko00000 Bacteria 1N2UF@1224,2UDEY@28211,COG1426@1,COG1426@2 NA|NA|NA K Protein conserved in bacteria JOKFNDED_03359 1396141.BATP01000025_gene929 1.9e-58 231.9 Verrucomicrobiae vsr GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 ko:K07458 ko00000,ko01000,ko03400 iB21_1397.ECBD_1686,iECD_1391.ECBD_1686 Bacteria 2IUWE@203494,46VYM@74201,COG3727@1,COG3727@2 NA|NA|NA L DNA mismatch endonuclease Vsr JOKFNDED_03360 497964.CfE428DRAFT_2738 2.4e-99 368.6 Bacteria ko:K07454 ko00000 Bacteria COG3440@1,COG3440@2 NA|NA|NA V regulation of methylation-dependent chromatin silencing JOKFNDED_03362 583355.Caka_2716 7.5e-35 152.9 Verrucomicrobia vapL ko:K21498 ko00000,ko02048 Bacteria 46T8Z@74201,COG3093@1,COG3093@2 NA|NA|NA K Plasmid maintenance system antidote protein, XRE family JOKFNDED_03363 583355.Caka_2717 6.1e-26 123.2 Verrucomicrobia ko:K07334 ko00000,ko02048 Bacteria 46T9E@74201,COG3549@1,COG3549@2 NA|NA|NA S RelE-like toxin of type II toxin-antitoxin system HigB JOKFNDED_03364 1442599.JAAN01000035_gene680 6.3e-42 176.4 Xanthomonadales ahcY GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 1MUQ2@1224,1RMW8@1236,1X33V@135614,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine JOKFNDED_03365 1396418.BATQ01000078_gene601 2.2e-77 296.2 Verrucomicrobiae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITK4@203494,46SCN@74201,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides JOKFNDED_03366 1396418.BATQ01000085_gene1134 4.1e-156 558.9 Verrucomicrobiae gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria 2IU06@203494,46UJ6@74201,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II/III secretion system short domain JOKFNDED_03367 1403819.BATR01000056_gene1762 7.6e-51 207.2 Verrucomicrobiae yhcW GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 5.4.2.6 ko:K01838,ko:K07025 ko00500,map00500 R02728,R11310 RC00408 ko00000,ko00001,ko01000 Bacteria 2IUD3@203494,46W9J@74201,COG0637@1,COG0637@2 NA|NA|NA S HAD-hyrolase-like JOKFNDED_03368 1380350.JIAP01000008_gene1964 5.8e-63 248.1 Phyllobacteriaceae strT Bacteria 1R5SD@1224,2U1JH@28211,43JTG@69277,COG0667@1,COG0667@2,COG0673@1,COG0673@2 NA|NA|NA C Aldo/keto reductase family JOKFNDED_03369 926550.CLDAP_06140 4.5e-124 451.1 Chloroflexi galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2G5QM@200795,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family JOKFNDED_03370 1403819.BATR01000181_gene6200 2.5e-63 249.2 Verrucomicrobia Bacteria 46WKR@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_03371 745411.B3C1_14982 5.1e-07 62.0 Gammaproteobacteria Bacteria 1N218@1224,1SAVY@1236,2C0Z2@1,32WKV@2 NA|NA|NA S Protein of unknown function (DUF3293) JOKFNDED_03372 1403819.BATR01000044_gene1275 2.2e-174 619.8 Verrucomicrobiae ko:K08309 ko00000,ko01000,ko01011 GH23 Bacteria 2IW3J@203494,46Z4T@74201,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03374 240016.ABIZ01000001_gene5646 1.6e-63 249.6 Verrucomicrobiae ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUVE@203494,46SY0@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_03375 240016.ABIZ01000001_gene5647 1.7e-32 145.6 Verrucomicrobiae aglS ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUY5@203494,46WPD@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_03376 240016.ABIZ01000001_gene5648 1.7e-37 162.2 Verrucomicrobiae exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUYI@203494,46W26@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_03377 240016.ABIZ01000001_gene5649 3.4e-83 315.5 Verrucomicrobiae Bacteria 294ZG@1,2IW27@203494,2ZSCB@2,46WKC@74201 NA|NA|NA S von Willebrand factor (vWF) type A domain JOKFNDED_03379 497964.CfE428DRAFT_0890 1.1e-52 213.8 Verrucomicrobia tyrA GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,1.3.1.13,1.3.1.43,1.3.1.78,2.5.1.19,3.6.3.34,5.4.99.5 ko:K00210,ko:K00211,ko:K00220,ko:K00800,ko:K02013,ko:K04517,ko:K14187,ko:K15226 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,ko02010,map00400,map00401,map01100,map01110,map01130,map01230,map02010 M00022,M00024,M00025,M00040,M00240 R00732,R00733,R01715,R01728,R01730,R03460 RC00125,RC00350,RC03116 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 iECUMN_1333.ECUMN_2925,iYO844.BSU22610 Bacteria 46SSN@74201,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase JOKFNDED_03382 1403819.BATR01000184_gene6360 3.1e-59 236.1 Verrucomicrobia 2.7.13.3 ko:K15011 ko02020,map02020 M00523 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 46U8F@74201,COG4191@1,COG4191@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain JOKFNDED_03383 1396418.BATQ01000179_gene3158 3.2e-62 245.4 Bacteria 2.4.1.268,2.4.1.83 ko:K00721,ko:K07011,ko:K12990,ko:K14597,ko:K21349 ko00510,ko00906,ko01100,ko02024,ko02025,map00510,map00906,map01100,map02024,map02025 R01009,R07544,R07546 RC00005,RC00262 ko00000,ko00001,ko01000,ko01003,ko01005 GT2,GT81 Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 JOKFNDED_03384 240016.ABIZ01000001_gene5345 1.6e-151 542.7 Verrucomicrobiae Bacteria 2CK74@1,2IVG1@203494,33FA9@2,46XCM@74201 NA|NA|NA S O-antigen ligase like membrane protein JOKFNDED_03385 240016.ABIZ01000001_gene5346 6.1e-135 487.6 Verrucomicrobiae Bacteria 2IW0Z@203494,46VXD@74201,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 JOKFNDED_03386 240016.ABIZ01000001_gene5347 3.5e-32 144.4 Verrucomicrobiae ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 2IVGU@203494,46XCW@74201,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis/export protein JOKFNDED_03387 240016.ABIZ01000001_gene5513 2.4e-209 735.3 Bacteria Bacteria COG5267@1,COG5267@2 NA|NA|NA S Protein of unknown function (DUF1800) JOKFNDED_03388 1403819.BATR01000010_gene371 2e-196 692.2 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03389 1403819.BATR01000010_gene372 4.7e-32 144.4 Verrucomicrobiae Bacteria 29N11@1,2IURX@203494,308YT@2,46ZGY@74201 NA|NA|NA JOKFNDED_03390 1519464.HY22_11920 1.3e-61 244.2 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_03391 215803.DB30_1485 1e-169 603.2 Myxococcales Bacteria 1QX4P@1224,2X4WY@28221,2YZS2@29,439K8@68525,COG2931@1,COG2931@2 NA|NA|NA Q PAP2 superfamily JOKFNDED_03393 1396141.BATP01000001_gene5335 7.8e-19 100.1 Verrucomicrobiae ko:K14987 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko02022 Bacteria 2IW32@203494,46VMR@74201,COG4566@1,COG4566@2 NA|NA|NA T cheY-homologous receiver domain JOKFNDED_03394 1396141.BATP01000001_gene5327 2.2e-61 242.3 Verrucomicrobiae ko:K14987 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko02022 Bacteria 2IVU6@203494,46WZ8@74201,COG4566@1,COG4566@2 NA|NA|NA T helix_turn_helix, Lux Regulon JOKFNDED_03395 1396418.BATQ01000120_gene3078 8.6e-111 407.9 Verrucomicrobiae Bacteria 2IV4D@203494,46ZJR@74201,COG4191@1,COG4191@2 NA|NA|NA T PAS domain JOKFNDED_03396 497964.CfE428DRAFT_2087 1.3e-104 386.3 Verrucomicrobia Bacteria 46SDC@74201,COG0500@1,COG0640@1,COG0640@2,COG2226@2 NA|NA|NA KQ helix_turn_helix, Arsenical Resistance Operon Repressor JOKFNDED_03397 4530.OS01T0323775-00 1.2e-53 217.2 Liliopsida Viridiplantae 2E697@1,2SD02@2759,3825A@33090,3GRTV@35493,3M8SX@4447 NA|NA|NA JOKFNDED_03402 509191.AEDB02000081_gene2506 3.6e-108 398.3 Bacteria Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion JOKFNDED_03403 497964.CfE428DRAFT_0142 1.6e-91 342.8 Bacteria Bacteria COG0330@1,COG0330@2 NA|NA|NA O stress-induced mitochondrial fusion JOKFNDED_03404 243090.RB395 1.2e-242 846.3 Planctomycetes Bacteria 2IWU7@203682,COG1020@1,COG1020@2 NA|NA|NA Q Protein of unknown function (DUF1587) JOKFNDED_03405 1267535.KB906767_gene2192 7.1e-80 303.9 Acidobacteriia Bacteria 2JJ3M@204432,3Y2JR@57723,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain JOKFNDED_03406 1123242.JH636436_gene121 1.2e-158 567.0 Planctomycetes safC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2IXSM@203682,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase activity JOKFNDED_03407 1123070.KB899247_gene1453 5e-94 351.3 Verrucomicrobiae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005623,GO:0005886,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057,ko:K07175 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 iJN678.gpsA,iJN746.PP_4169 Bacteria 2ITRT@203494,46SQJ@74201,COG0240@1,COG0240@2 NA|NA|NA C NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus JOKFNDED_03408 1396418.BATQ01000142_gene3282 5e-50 204.5 Verrucomicrobiae plsY 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IUDC@203494,46VTA@74201,COG0344@1,COG0344@2 NA|NA|NA I Glycerol-3-phosphate acyltransferase JOKFNDED_03409 382464.ABSI01000011_gene2354 5.1e-88 330.9 Verrucomicrobiae grxC ko:K03676 ko00000,ko03110 Bacteria 2IVIC@203494,46XX2@74201,COG0695@1,COG0695@2 NA|NA|NA O DoxX JOKFNDED_03410 497964.CfE428DRAFT_4791 6.1e-110 404.1 Verrucomicrobia yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7,2.5.1.18 ko:K00799,ko:K07393 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373 Bacteria 46S81@74201,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain JOKFNDED_03411 525897.Dbac_1167 3.7e-154 551.6 Desulfovibrionales 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MUDN@1224,2MA27@213115,2WJSC@28221,42N3H@68525,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese domain protein JOKFNDED_03412 153721.MYP_3317 2.2e-24 119.0 Cytophagia Bacteria 47RV4@768503,4NSMY@976,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) JOKFNDED_03414 595460.RRSWK_04978 1.8e-72 278.9 Planctomycetes pfpI 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 2J1JC@203682,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family JOKFNDED_03415 497964.CfE428DRAFT_3169 1.7e-81 310.1 Verrucomicrobia kdtA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 iECNA114_1301.ECNA114_3778,iIT341.HP0957,iUMNK88_1353.UMNK88_4417 Bacteria 46SK9@74201,COG1519@1,COG1519@2 NA|NA|NA M PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein JOKFNDED_03416 240016.ABIZ01000001_gene4602 1.1e-40 173.3 Verrucomicrobiae rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IUEM@203494,46T62@74201,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 JOKFNDED_03417 240016.ABIZ01000001_gene479 5.3e-98 365.9 Verrucomicrobiae yicH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2IUJJ@203494,46SSM@74201,COG2982@1,COG2982@2 NA|NA|NA M AsmA-like C-terminal region JOKFNDED_03418 344747.PM8797T_25131 1.1e-252 879.8 Planctomycetes Bacteria 2IXCI@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C COG2133 Glucose sorbosone dehydrogenases JOKFNDED_03419 1396141.BATP01000054_gene2917 1.8e-269 936.0 Verrucomicrobiae hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 2IU1J@203494,46TFT@74201,COG1643@1,COG1643@2 NA|NA|NA L Oligonucleotide/oligosaccharide-binding (OB)-fold JOKFNDED_03420 1298858.AUEL01000017_gene2814 2.9e-130 471.9 Phyllobacteriaceae ko:K07133 ko00000 Bacteria 1MWBT@1224,2U050@28211,43I4B@69277,COG1373@1,COG1373@2 NA|NA|NA S AAA domain JOKFNDED_03421 1304885.AUEY01000096_gene2839 2.3e-110 406.4 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_03422 497964.CfE428DRAFT_0327 2.7e-17 97.8 Verrucomicrobia Bacteria 46UDB@74201,COG1361@1,COG1361@2,COG1404@1,COG1404@2,COG4733@1,COG4733@2 NA|NA|NA G Domain of unknown function (DUF5122) beta-propeller JOKFNDED_03423 1123508.JH636439_gene1312 2.5e-30 139.0 Planctomycetes ko:K03088 ko00000,ko03021 Bacteria 2IZ9U@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_03426 596151.DesfrDRAFT_0107 4.3e-10 72.4 Desulfovibrionales Bacteria 1Q1I4@1224,2MBS0@213115,2X2E8@28221,437A0@68525,COG2204@1,COG2204@2 NA|NA|NA T Response regulator receiver JOKFNDED_03427 1396418.BATQ01000161_gene5597 2.1e-105 388.7 Bacteria Bacteria COG1423@1,COG1423@2 NA|NA|NA L RNA ligase JOKFNDED_03428 1396418.BATQ01000161_gene5598 5.9e-128 464.2 Bacteria Bacteria COG4639@1,COG4639@2 NA|NA|NA Q AAA domain JOKFNDED_03430 344747.PM8797T_11726 7.4e-82 310.8 Planctomycetes Bacteria 2IX0E@203682,COG3828@1,COG3828@2 NA|NA|NA S PFAM Trehalose utilisation JOKFNDED_03434 1403819.BATR01000002_gene68 5.8e-23 115.2 Verrucomicrobiae Bacteria 2AW6M@1,2IV0K@203494,31N1N@2,46X8K@74201 NA|NA|NA JOKFNDED_03435 349741.Amuc_1100 1.2e-10 74.3 Verrucomicrobiae Bacteria 28V7G@1,2IUZ5@203494,2ZHAM@2,46WJH@74201 NA|NA|NA JOKFNDED_03436 497964.CfE428DRAFT_4611 1.9e-109 403.3 Verrucomicrobia ko:K02662 ko00000,ko02035,ko02044 Bacteria 46UI7@74201,COG4972@1,COG4972@2 NA|NA|NA NU Type IV pilus assembly protein PilM; JOKFNDED_03437 1396141.BATP01000025_gene901 2.3e-18 99.4 Verrucomicrobiae Bacteria 28VCA@1,2IUQZ@203494,2ZHF0@2,46WID@74201 NA|NA|NA JOKFNDED_03438 1396418.BATQ01000167_gene1762 2.1e-137 495.4 Verrucomicrobiae rfbB 4.1.1.35,4.2.1.46 ko:K01710,ko:K08678 ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00793 R01384,R06513 RC00402,RC00508 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITWW@203494,46S80@74201,COG0451@1,COG0451@2 NA|NA|NA GM GDP-mannose 4,6 dehydratase JOKFNDED_03440 1396418.BATQ01000072_gene543 2.1e-12 78.2 Verrucomicrobiae CP_0960 GO:0008150,GO:0040007 ko:K06960 ko00000 Bacteria 2IUUH@203494,46X7A@74201,COG1837@1,COG1837@2 NA|NA|NA S KH domain JOKFNDED_03441 1123070.KB899247_gene1580 2.1e-22 111.3 Verrucomicrobiae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IUP4@203494,46WC2@74201,COG0228@1,COG0228@2 NA|NA|NA J Ribosomal protein S16 JOKFNDED_03443 497964.CfE428DRAFT_5240 2.1e-128 465.3 Verrucomicrobia Bacteria 46SAH@74201,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) JOKFNDED_03445 56780.SYN_00851 1e-33 150.6 Syntrophobacterales oprM_1 Bacteria 1MUA8@1224,2MQAX@213462,2WIQX@28221,42MRU@68525,COG1538@1,COG1538@2 NA|NA|NA M Outer membrane efflux protein JOKFNDED_03447 243090.RB3612 1.1e-58 233.4 Planctomycetes Bacteria 2J1H9@203682,COG3448@1,COG3448@2 NA|NA|NA T HPP family JOKFNDED_03448 1403819.BATR01000118_gene4169 4.5e-21 107.8 Verrucomicrobiae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2IURG@203494,46TBP@74201,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 JOKFNDED_03449 240016.ABIZ01000001_gene3151 7.8e-233 813.1 Verrucomicrobiae araB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008741,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046373,GO:0046835,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 iBWG_1329.BWG_0059,iECH74115_1262.ECH74115_0068,iECSP_1301.ECSP_0067,iECs_1301.ECs0067,iG2583_1286.G2583_0066,iPC815.YPO2254,iZ_1308.Z0072 Bacteria 2ITGU@203494,46UI3@74201,COG1069@1,COG1069@2 NA|NA|NA C FGGY family of carbohydrate kinases, C-terminal domain JOKFNDED_03451 1396141.BATP01000019_gene1728 3.7e-26 125.6 Verrucomicrobia Bacteria 29XKE@1,30JBI@2,46WEB@74201 NA|NA|NA S Protein of unknown function (DUF3108) JOKFNDED_03452 1396418.BATQ01000109_gene4732 1.8e-06 60.5 Verrucomicrobiae 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2IWIN@203494,46T0C@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ enzyme repeat JOKFNDED_03453 1403819.BATR01000118_gene4176 1.5e-173 615.9 Verrucomicrobiae 1.3.98.3,2.1.1.342 ko:K02495,ko:K21936 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895,R11700 RC00884 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWKM@203494,46U2R@74201,COG0635@1,COG0635@2 NA|NA|NA H Elongator protein 3, MiaB family, Radical SAM JOKFNDED_03454 1403819.BATR01000118_gene4175 2.6e-27 129.0 Verrucomicrobia Bacteria 46WDJ@74201,COG3161@1,COG3161@2 NA|NA|NA H chorismate lyase activity JOKFNDED_03455 521674.Plim_1957 1.1e-54 222.6 Planctomycetes ko:K02305,ko:K08738,ko:K09992 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 Bacteria 2IY3G@203682,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3474@1,COG3474@2,COG3828@1,COG3828@2 NA|NA|NA C PFAM coagulation factor 5 8 type JOKFNDED_03458 744979.R2A130_2835 2.8e-12 78.2 Alphaproteobacteria doeB ko:K06987 ko00000 Bacteria 1MUAA@1224,2TRVI@28211,COG3608@1,COG3608@2 NA|NA|NA S succinylglutamate desuccinylase JOKFNDED_03459 1303518.CCALI_00393 1.4e-100 373.6 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity JOKFNDED_03460 485915.Dret_2330 4.4e-21 108.2 Deltaproteobacteria Bacteria 1MZ60@1224,2WW9K@28221,431TK@68525,COG3952@1,COG3952@2 NA|NA|NA S PFAM lipid A biosynthesis domain protein JOKFNDED_03462 1403819.BATR01000031_gene1020 5.4e-220 771.2 Verrucomicrobia ape2 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 46VZF@74201,COG0308@1,COG0308@2 NA|NA|NA E Peptidase family M1 domain JOKFNDED_03463 631362.Thi970DRAFT_00601 8.9e-41 174.9 Chromatiales mauB GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1,1.4.9.2,3.2.1.89,3.4.17.14 ko:K01224,ko:K07260,ko:K13372,ko:K15229,ko:K17285 ko00350,ko00360,ko00550,ko00680,ko00950,ko01100,ko01110,ko01120,ko01502,ko02020,map00350,map00360,map00550,map00680,map00950,map01100,map01110,map01120,map01502,map02020 M00651 R00606,R02382,R02612,R04300 RC00062,RC00189 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko04147 Bacteria 1MZ84@1224,1SFYU@1236,1X0NT@135613,COG2340@1,COG2340@2,COG3391@1,COG3391@2 NA|NA|NA S Cysteine-rich secretory protein family JOKFNDED_03464 497964.CfE428DRAFT_5405 7.5e-209 733.4 Verrucomicrobia MA20_28645 3.6.3.29,3.6.3.41 ko:K06022,ko:K06158,ko:K10834 ko00000,ko01000,ko03012 Bacteria 46UDK@74201,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter JOKFNDED_03467 1121271.AUCM01000026_gene1301 8.7e-29 133.3 Alphaproteobacteria vapC ko:K07062 ko00000,ko01000,ko02048 Bacteria 1RIB5@1224,2UAIV@28211,COG1487@1,COG1487@2 NA|NA|NA D Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_03469 686340.Metal_1927 5.7e-79 300.8 Methylococcales vioA GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771 2.6.1.33 ko:K13308,ko:K20429 ko00523,ko01130,map00523,map01130 M00797 R02773 RC00006,RC00781 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPN@1224,1RMCS@1236,1XDT2@135618,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family JOKFNDED_03470 1121405.dsmv_3790 3.6e-24 118.6 Deltaproteobacteria Bacteria 1MZ7U@1224,2WRJG@28221,42W1P@68525,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) JOKFNDED_03471 530564.Psta_3105 3e-72 278.5 Planctomycetes ypfJ GO:0005575,GO:0005576 ko:K07054 ko00000 Bacteria 2IZ1Y@203682,COG2321@1,COG2321@2 NA|NA|NA S Putative neutral zinc metallopeptidase JOKFNDED_03472 1396141.BATP01000027_gene1063 2.2e-118 432.6 Verrucomicrobiae pabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01665,ko:K03342,ko:K13503,ko:K13950 ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2IU1N@203494,46UHC@74201,COG0147@1,COG0147@2 NA|NA|NA EH chorismate binding enzyme JOKFNDED_03473 1396418.BATQ01000056_gene238 8.8e-123 446.8 Verrucomicrobiae ko:K11384 ko02020,map02020 M00505 ko00000,ko00001,ko00002,ko02022 Bacteria 2IV20@203494,46TZX@74201,COG2204@1,COG2204@2 NA|NA|NA T Sigma-54 interaction domain JOKFNDED_03475 1396418.BATQ01000056_gene241 9e-43 180.3 Bacteria Bacteria COG3685@1,COG3685@2 NA|NA|NA S cellular response to DNA damage stimulus JOKFNDED_03480 595460.RRSWK_06264 7.2e-51 207.6 Planctomycetes 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2IXPY@203682,COG1073@1,COG1073@2 NA|NA|NA I acetylesterase activity JOKFNDED_03481 261292.Nit79A3_2553 2.9e-19 103.2 Bacteria Bacteria 2AZY1@1,31S7T@2 NA|NA|NA JOKFNDED_03482 1396141.BATP01000035_gene4008 3.9e-166 591.3 Verrucomicrobiae 3.1.6.12 ko:K01135 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 2IV4W@203494,46ZIZ@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_03483 521674.Plim_2385 1.3e-68 266.2 Planctomycetes Bacteria 2IZ1Z@203682,COG3828@1,COG3828@2 NA|NA|NA S Domain of Unknown Function (DUF1080) JOKFNDED_03484 1403819.BATR01000051_gene1540 6.1e-106 391.0 Verrucomicrobiae 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2ITT7@203494,46TWC@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2,COG3828@1,COG3828@2 NA|NA|NA CEG Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_03485 317619.ANKN01000111_gene1548 2.5e-36 158.7 Cyanobacteria Bacteria 1G5FE@1117,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_03488 195105.CN97_10380 3.6e-192 677.6 Alphaproteobacteria sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVCE@1224,2TRXK@28211,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit JOKFNDED_03489 1300350.DSW25_05860 2.8e-113 416.0 Sulfitobacter mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1360 Bacteria 1MV57@1224,2TSV6@28211,3ZWD0@60136,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate JOKFNDED_03490 323850.Shew_0766 4.1e-55 222.2 Shewanellaceae Bacteria 1PEVY@1224,1RPEQ@1236,2QA9E@267890,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_03491 1123070.KB899260_gene2032 4.7e-79 302.8 Verrucomicrobiae Bacteria 2IV7W@203494,46ZJD@74201,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_03493 1396141.BATP01000060_gene4644 1.1e-122 446.4 Verrucomicrobiae oppD GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02031,ko:K02032,ko:K02034,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 iECED1_1282.ECED1_1398,iLF82_1304.LF82_1573,iSBO_1134.SBO_1821 Bacteria 2ITGK@203494,46U0J@74201,COG0444@1,COG0444@2 NA|NA|NA EP Oligopeptide/dipeptide transporter, C-terminal region JOKFNDED_03494 1396141.BATP01000004_gene5926 1e-78 300.4 Verrucomicrobiae Bacteria 2EYYY@1,2ITNH@203494,33S5Q@2,46UHA@74201 NA|NA|NA S Fungal chitosanase of glycosyl hydrolase group 75 JOKFNDED_03495 1123070.KB899253_gene998 1.2e-59 236.9 Verrucomicrobiae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 2IUD8@203494,46SUQ@74201,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP JOKFNDED_03496 349741.Amuc_1825 1.7e-81 309.7 Verrucomicrobiae tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 2ITPM@203494,46SM8@74201,COG1189@1,COG1189@2 NA|NA|NA J FtsJ-like methyltransferase JOKFNDED_03497 314230.DSM3645_07156 2.4e-138 499.2 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IWSJ@203682,COG5492@1,COG5492@2 NA|NA|NA N Protein of unknown function (DUF1549) JOKFNDED_03498 530564.Psta_1875 1.5e-122 446.4 Planctomycetes Bacteria 2IXSP@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03499 344747.PM8797T_27844 9.9e-73 280.0 Planctomycetes Bacteria 2IXAF@203682,COG2133@1,COG2133@2 NA|NA|NA G glucose sorbosone JOKFNDED_03500 497964.CfE428DRAFT_4065 3.2e-146 524.6 Verrucomicrobia 1.1.1.399,1.1.1.95 ko:K00058,ko:K04496 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko04310,ko04330,ko05200,ko05220,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map04310,map04330,map05200,map05220 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 46SAN@74201,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase JOKFNDED_03504 497964.CfE428DRAFT_2769 6.7e-166 590.5 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03505 243090.RB11811 1.5e-97 363.2 Planctomycetes Bacteria 2IYGB@203682,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_03506 1396141.BATP01000023_gene625 1e-75 290.0 Verrucomicrobiae sodB 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 2IVBY@203494,46XBN@74201,COG0605@1,COG0605@2 NA|NA|NA P Iron/manganese superoxide dismutases, alpha-hairpin domain JOKFNDED_03507 1403819.BATR01000022_gene780 1.6e-186 659.4 Verrucomicrobiae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITR5@203494,46UKY@74201,COG0514@1,COG0514@2 NA|NA|NA L RecQ zinc-binding JOKFNDED_03508 478741.JAFS01000001_gene1470 1.5e-19 102.4 Verrucomicrobia GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 46SU7@74201,COG3178@1,COG3178@2 NA|NA|NA S Phosphotransferase enzyme family JOKFNDED_03509 1396141.BATP01000039_gene1260 5.3e-15 86.7 Verrucomicrobiae Bacteria 2IUAX@203494,46SQK@74201,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain JOKFNDED_03510 497964.CfE428DRAFT_5007 8.8e-82 310.5 Verrucomicrobia MA20_21580 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 46VH4@74201,COG2897@1,COG2897@2 NA|NA|NA P YceI-like domain JOKFNDED_03511 263358.VAB18032_00035 1e-15 90.5 Micromonosporales yedK Bacteria 2GKY8@201174,4DD0W@85008,COG2135@1,COG2135@2 NA|NA|NA S Belongs to the SOS response-associated peptidase family JOKFNDED_03512 349741.Amuc_0094 8.6e-21 105.9 Verrucomicrobiae rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUU2@203494,46TBC@74201,COG0238@1,COG0238@2 NA|NA|NA J Ribosomal protein S18 JOKFNDED_03513 349741.Amuc_0095 3.2e-17 93.6 Verrucomicrobiae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUS7@203494,46T91@74201,COG0267@1,COG0267@2 NA|NA|NA J Ribosomal protein L33 JOKFNDED_03514 497964.CfE428DRAFT_2343 1.1e-37 164.5 Verrucomicrobia dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 46SVY@74201,COG1734@1,COG1734@2 NA|NA|NA T Prokaryotic dksA/traR C4-type zinc finger JOKFNDED_03515 1396141.BATP01000027_gene1118 7.6e-30 136.3 Verrucomicrobiae hup ko:K03530,ko:K04764 ko00000,ko03032,ko03036,ko03400 Bacteria 2IUR0@203494,46T4V@74201,COG0776@1,COG0776@2 NA|NA|NA L bacterial (prokaryotic) histone like domain JOKFNDED_03516 1396141.BATP01000027_gene1120 3.1e-81 308.9 Verrucomicrobiae mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITPI@203494,46SR4@74201,COG1194@1,COG1194@2 NA|NA|NA L endonuclease III JOKFNDED_03517 768671.ThimaDRAFT_2806 1.3e-181 642.9 Chromatiales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1MU96@1224,1RP2Q@1236,1WXDN@135613,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification JOKFNDED_03518 768671.ThimaDRAFT_2806 2.7e-203 714.9 Chromatiales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1MU96@1224,1RP2Q@1236,1WXDN@135613,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification JOKFNDED_03519 1442599.JAAN01000041_gene3092 2.4e-23 115.5 Xanthomonadales ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1QCFS@1224,1T864@1236,1XA78@135614,COG1487@1,COG1487@2 NA|NA|NA S ribonuclease activity JOKFNDED_03520 1442599.JAAN01000041_gene3091 3.1e-43 182.2 Xanthomonadales Bacteria 1QFTM@1224,1TD3X@1236,1XA2N@135614,28HY7@1,2Z83N@2 NA|NA|NA JOKFNDED_03521 56107.Cylst_1641 6.1e-52 211.1 Nostocales Bacteria 1G3HG@1117,1HJ0W@1161,2DBHY@1,2Z9DM@2 NA|NA|NA JOKFNDED_03522 1173020.Cha6605_1255 2.6e-49 202.6 Cyanobacteria Bacteria 1G6PP@1117,COG3550@1,COG3550@2 NA|NA|NA S peptidyl-serine autophosphorylation JOKFNDED_03523 743299.Acife_0669 7.2e-52 211.5 Gammaproteobacteria 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1MXSQ@1224,1S320@1236,COG0732@1,COG0732@2 NA|NA|NA V restriction modification system DNA specificity JOKFNDED_03524 243090.RB11379 3.5e-254 884.4 Planctomycetes hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2IXMQ@203682,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system JOKFNDED_03525 240016.ABIZ01000001_gene1534 1.4e-174 620.2 Bacteria hhoB 3.4.21.107 ko:K04771,ko:K08372 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria COG0265@1,COG0265@2,COG2912@1,COG2912@2 NA|NA|NA P Transglutaminase-like superfamily JOKFNDED_03526 497964.CfE428DRAFT_4499 2.8e-89 335.9 Verrucomicrobia ko:K02574,ko:K21559 ko00000,ko03000 Bacteria 46UK4@74201,COG0348@1,COG0348@2 NA|NA|NA C FMN_bind JOKFNDED_03528 497964.CfE428DRAFT_0303 5e-65 254.6 Bacteria ybaJ Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase JOKFNDED_03529 497964.CfE428DRAFT_4949 1e-89 337.4 Verrucomicrobia Bacteria 46UCM@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_03530 497964.CfE428DRAFT_1793 9.4e-94 350.1 Verrucomicrobia truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 46SJR@74201,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs JOKFNDED_03532 232348.ADXL01000014_gene730 5.7e-20 103.6 Synechococcus Bacteria 1G6S3@1117,1H23Q@1129,COG4634@1,COG4634@2 NA|NA|NA JOKFNDED_03533 497964.CfE428DRAFT_3300 9.2e-14 82.4 Bacteria Bacteria COG2442@1,COG2442@2 NA|NA|NA K InterPro IPR007367 JOKFNDED_03534 497964.CfE428DRAFT_2970 5.1e-52 211.5 Verrucomicrobia Bacteria 2F4YG@1,33XKC@2,46VC2@74201 NA|NA|NA JOKFNDED_03536 1396418.BATQ01000012_gene4419 3.6e-40 171.8 Verrucomicrobiae Bacteria 29K80@1,2IUP2@203494,3075E@2,46ZG4@74201 NA|NA|NA JOKFNDED_03537 497964.CfE428DRAFT_3322 3.1e-94 352.1 Verrucomicrobia ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 46U6U@74201,COG0715@1,COG0715@2 NA|NA|NA P Protein of unknown function (DUF3500) JOKFNDED_03538 335543.Sfum_2034 2e-97 362.1 Syntrophobacterales aqpZ GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 iJN678.apqZ Bacteria 1MXTJ@1224,2MQQR@213462,2WM3M@28221,42MR4@68525,COG0580@1,COG0580@2 NA|NA|NA G Belongs to the MIP aquaporin (TC 1.A.8) family JOKFNDED_03539 1469557.JSWF01000012_gene1215 9.1e-104 383.3 Flavobacteriia Bacteria 1HZ70@117743,4NFMV@976,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family JOKFNDED_03540 1434325.AZQN01000002_gene1153 1.4e-93 350.5 Cytophagia Bacteria 47T92@768503,4NE6V@976,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_03541 278957.ABEA03000195_gene508 1.6e-122 446.8 Bacteria Bacteria 2DU9K@1,33PHS@2 NA|NA|NA S BNR repeat-like domain JOKFNDED_03542 497964.CfE428DRAFT_1945 5.3e-230 803.5 Verrucomicrobia Bacteria 46TDE@74201,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_03543 497964.CfE428DRAFT_1946 0.0 1229.9 Verrucomicrobia Bacteria 46V03@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_03544 240016.ABIZ01000001_gene764 5.6e-105 388.3 Verrucomicrobiae Bacteria 2IVBK@203494,46ZJS@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_03545 756272.Plabr_3222 3.4e-93 349.4 Planctomycetes 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2J1V6@203682,COG3540@1,COG3540@2 NA|NA|NA P PhoD-like phosphatase JOKFNDED_03546 497964.CfE428DRAFT_1947 1.1e-59 236.1 Verrucomicrobia Bacteria 46UX6@74201,COG3712@1,COG3712@2 NA|NA|NA PT FecR protein JOKFNDED_03547 1396141.BATP01000012_gene2704 1.4e-100 372.9 Verrucomicrobiae uxaC GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528 Bacteria 2ITWJ@203494,46SH8@74201,COG1904@1,COG1904@2 NA|NA|NA G Glucuronate isomerase JOKFNDED_03548 1452718.JBOY01000044_gene1254 6.2e-83 314.7 Gammaproteobacteria 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 1QXST@1224,1T3HY@1236,COG0578@1,COG0578@2 NA|NA|NA C COG0578 Glycerol-3-phosphate dehydrogenase JOKFNDED_03549 1499686.BN1079_01959 1.2e-66 260.0 Gammaproteobacteria Bacteria 1PDY4@1224,1RQYV@1236,COG0667@1,COG0667@2 NA|NA|NA C Aldo Keto reductase JOKFNDED_03550 794903.OPIT5_16460 1.6e-85 322.8 Opitutae GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 3K8DP@414999,46U67@74201,COG1387@1,COG1387@2 NA|NA|NA E PHP domain JOKFNDED_03552 1313172.YM304_04040 4e-09 68.6 Actinobacteria ccoP ko:K00406,ko:K08906 ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko00194 3.D.4.3 Bacteria 2H49G@201174,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_03553 1382359.JIAL01000001_gene1389 4.1e-36 159.8 Acidobacteria Bacteria 3Y67U@57723,COG0457@1,COG0457@2 NA|NA|NA O ASPIC and UnbV JOKFNDED_03554 1123070.KB899261_gene2119 7e-91 340.9 Verrucomicrobiae trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITKX@203494,46SQA@74201,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) JOKFNDED_03555 1396418.BATQ01000045_gene6082 1.5e-42 179.5 Verrucomicrobiae yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07735 ko00000,ko03000 Bacteria 2IUUZ@203494,46VUF@74201,COG1678@1,COG1678@2 NA|NA|NA K Uncharacterized ACR, COG1678 JOKFNDED_03556 1396141.BATP01000005_gene6087 2e-26 125.6 Verrucomicrobiae Bacteria 2IUVV@203494,46T65@74201,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus JOKFNDED_03557 1210884.HG799465_gene12061 2.3e-46 191.8 Planctomycetes Bacteria 2IZKD@203682,COG0251@1,COG0251@2 NA|NA|NA J translation initiation inhibitor, yjgF family JOKFNDED_03558 794903.OPIT5_01475 2.2e-151 542.3 Opitutae CP_1013 2.7.7.23,2.7.7.83 ko:K00972,ko:K11442 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00361,M00362 R00416 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7T1@414999,46U9U@74201,COG4284@1,COG4284@2 NA|NA|NA G UTP--glucose-1-phosphate uridylyltransferase JOKFNDED_03559 344747.PM8797T_06842 1.2e-50 206.8 Planctomycetes proC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 iIT341.HP1158 Bacteria 2IY5U@203682,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline JOKFNDED_03560 240016.ABIZ01000001_gene3168 1.6e-103 382.9 Verrucomicrobiae bfmBA 1.2.4.1,1.2.4.4 ko:K00161,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2ITWI@203494,46UAY@74201,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component JOKFNDED_03561 240016.ABIZ01000001_gene1235 3.7e-116 424.9 Verrucomicrobiae gutB 1.1.1.14,1.1.1.303,1.1.1.4 ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 M00014 R00875,R01896,R02855,R02946,R10504 RC00085,RC00102,RC00205,RC00525 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITRM@203494,46YXT@74201,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain JOKFNDED_03563 497964.CfE428DRAFT_3025 1.5e-48 199.5 Verrucomicrobia 2.1.1.67 ko:K00569 ko00983,map00983 R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 Bacteria 46SYP@74201,COG0500@1,COG0500@2 NA|NA|NA Q Thiopurine S-methyltransferase (TPMT) JOKFNDED_03564 1396141.BATP01000004_gene5855 4.4e-22 111.3 Verrucomicrobiae Bacteria 2FBS3@1,2IUQ7@203494,343WW@2,46X6J@74201 NA|NA|NA JOKFNDED_03565 1403819.BATR01000124_gene4416 4.4e-47 196.1 Bacteria Bacteria COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase activity JOKFNDED_03567 344747.PM8797T_26720 1.9e-40 172.9 Planctomycetes Bacteria 2J0Z6@203682,COG1414@1,COG1414@2 NA|NA|NA K Transcriptional regulator JOKFNDED_03571 864702.OsccyDRAFT_3910 2.6e-09 69.7 Oscillatoriales 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1G4X1@1117,1HAE3@1150,COG2755@1,COG2755@2,COG2931@1,COG2931@2 NA|NA|NA Q PFAM Hemolysin-type calcium-binding repeat (2 copies) JOKFNDED_03572 497964.CfE428DRAFT_0857 3.2e-70 272.7 Verrucomicrobia wbjE Bacteria 46V30@74201,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_03574 497964.CfE428DRAFT_4244 1.4e-295 1022.7 Verrucomicrobia Bacteria 46TVM@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C HEAT repeats JOKFNDED_03575 525146.Ddes_2357 1.7e-130 472.6 Desulfovibrionales fic Bacteria 1MV69@1224,2M8BN@213115,2WJHZ@28221,42MB3@68525,COG3177@1,COG3177@2 NA|NA|NA S Domain of unknown function (DUF4172) JOKFNDED_03576 1122132.AQYH01000003_gene3184 4.2e-117 427.9 Rhizobiaceae Bacteria 1MXUP@1224,2TV6R@28211,4BMCT@82115,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03577 1296416.JACB01000051_gene2698 1.2e-47 196.8 Aquimarina fabG3 1.1.1.53 ko:K00038 ko00140,ko01100,map00140,map01100 R04831,R04834,R04844,R04847 RC00139,RC01219,RC01220 ko00000,ko00001,ko01000 Bacteria 1IJAA@117743,2YKI8@290174,4PKIR@976,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase JOKFNDED_03578 344747.PM8797T_12533 1e-30 139.4 Bacteria Bacteria 2DMM9@1,32SDB@2 NA|NA|NA JOKFNDED_03579 1121012.AUKX01000079_gene517 7e-53 214.5 Arenibacter 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1IEMK@117743,23FNH@178469,4PE5U@976,COG0451@1,COG0451@2 NA|NA|NA GM GDP-mannose 4,6 dehydratase JOKFNDED_03580 530564.Psta_3090 3.8e-36 158.7 Planctomycetes cheR 2.1.1.80,2.7.13.3,3.1.1.61 ko:K10125,ko:K13924 ko02020,ko02030,map02020,map02030 M00504,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 2J540@203682,COG3829@1,COG3829@2,COG4977@1,COG4977@2 NA|NA|NA K SMART helix-turn-helix- domain containing protein AraC type JOKFNDED_03581 1396141.BATP01000021_gene151 7.4e-25 120.6 Verrucomicrobiae Bacteria 2IW78@203494,46W8U@74201,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain JOKFNDED_03583 641491.DND132_1275 7.3e-42 179.1 Desulfovibrionales 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1V@1224,2M92Z@213115,2WIUS@28221,42N5S@68525,COG2114@1,COG2114@2,COG4252@1,COG4252@2 NA|NA|NA T SMART Adenylyl cyclase class-3 4 guanylyl cyclase JOKFNDED_03585 1142394.PSMK_22500 4.3e-08 65.5 Planctomycetes Bacteria 2DPEK@1,2J1AM@203682,331S2@2 NA|NA|NA JOKFNDED_03586 240016.ABIZ01000001_gene786 2e-112 412.5 Verrucomicrobiae manC 2.7.7.13,5.3.1.8,5.4.2.8 ko:K00971,ko:K01840,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01818,R01819 RC00002,RC00376,RC00408 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS00940 Bacteria 2ITXZ@203494,46SAQ@74201,COG0836@1,COG0836@2 NA|NA|NA M Nucleotidyl transferase JOKFNDED_03587 1123070.KB899259_gene1959 1e-27 129.8 Verrucomicrobiae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2IUHN@203494,46T51@74201,COG0816@1,COG0816@2 NA|NA|NA L Likely ribonuclease with RNase H fold. JOKFNDED_03588 1403819.BATR01000183_gene6332 3.6e-198 698.4 Bacteria ptrB GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Bacteria COG1770@1,COG1770@2 NA|NA|NA E oligopeptidase activity JOKFNDED_03589 595460.RRSWK_02531 3.4e-65 256.9 Planctomycetes GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2J3QW@203682,COG1611@1,COG1611@2,COG1672@1,COG1672@2 NA|NA|NA S AAA ATPase domain JOKFNDED_03590 595460.RRSWK_02530 3.9e-104 385.2 Planctomycetes Bacteria 2J46B@203682,COG1672@1,COG1672@2 NA|NA|NA S PFAM Archaeal ATPase JOKFNDED_03591 240016.ABIZ01000001_gene273 1.5e-59 236.1 Verrucomicrobiae adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IU4Q@203494,46SW4@74201,COG0563@1,COG0563@2 NA|NA|NA F Adenylate kinase JOKFNDED_03592 187272.Mlg_2099 4.3e-99 367.9 Chromatiales purU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.72,3.5.1.10 ko:K00974,ko:K01433 ko00630,ko00670,ko03013,map00630,map00670,map03013 R00944,R09382,R09383,R09384,R09386 RC00026,RC00078,RC00111 ko00000,ko00001,ko01000,ko03016 iSDY_1059.SDY_1284 Bacteria 1MVCF@1224,1RN6Q@1236,1WXFH@135613,COG0788@1,COG0788@2 NA|NA|NA F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) JOKFNDED_03594 497964.CfE428DRAFT_4840 7.9e-171 607.1 Verrucomicrobia comM ko:K07391 ko00000 Bacteria 46SAK@74201,COG0606@1,COG0606@2 NA|NA|NA O PFAM magnesium chelatase ChlI subunit JOKFNDED_03596 497964.CfE428DRAFT_5599 2.8e-36 158.3 Bacteria vapC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07064 ko00000 Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_03597 1255043.TVNIR_0772 1.1e-09 68.9 Proteobacteria GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 Bacteria 1R3M4@1224,2DSQK@1,33H2H@2 NA|NA|NA JOKFNDED_03598 419947.MRA_3362 1.4e-29 136.0 Mycobacteriaceae vapC44 GO:0005575,GO:0005576 ko:K07064 ko00000 Bacteria 23DQN@1762,2IPRK@201174,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_03599 349741.Amuc_0791 1.2e-52 213.0 Verrucomicrobia nirJ ko:K22226 ko00000 Bacteria 46T4P@74201,COG0535@1,COG0535@2 NA|NA|NA C SMART Elongator protein 3 MiaB NifB JOKFNDED_03600 349741.Amuc_0792 9.2e-118 430.3 Verrucomicrobia ko:K22227 ko00000 Bacteria 46T4P@74201,COG0535@1,COG0535@2 NA|NA|NA C SMART Elongator protein 3 MiaB NifB JOKFNDED_03601 1123392.AQWL01000007_gene986 8.9e-26 122.5 Betaproteobacteria ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1QXHE@1224,2VWIU@28216,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin domain JOKFNDED_03602 1396141.BATP01000005_gene5999 3.7e-31 141.0 Verrucomicrobiae ytcD Bacteria 2IVUA@203494,46WWY@74201,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix JOKFNDED_03603 1210884.HG799463_gene9740 1.5e-68 266.2 Planctomycetes yiiM GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0098754 Bacteria 2IZG5@203682,COG2258@1,COG2258@2 NA|NA|NA S MOSC domain JOKFNDED_03604 1396418.BATQ01000008_gene1477 3.2e-29 134.8 Verrucomicrobiae ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Bacteria 2IW2G@203494,46WCQ@74201,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator JOKFNDED_03605 671143.DAMO_0802 5e-27 127.9 Bacteria 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria COG1622@1,COG1622@2 NA|NA|NA C oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor JOKFNDED_03607 1205680.CAKO01000040_gene728 8.6e-97 359.8 Rhodospirillales Bacteria 1QUY6@1224,2JR9Y@204441,2TWZ0@28211,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily JOKFNDED_03608 1403819.BATR01000183_gene6340 5.3e-22 111.3 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_03609 305900.GV64_03600 5.2e-29 134.0 Oceanospirillales phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 1N1JG@1224,1S98R@1236,1XKGA@135619,COG2824@1,COG2824@2 NA|NA|NA P Alkylphosphonate utilization operon protein PhnA JOKFNDED_03610 1396141.BATP01000007_gene5629 1.3e-30 141.0 Bacteria 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria COG0204@1,COG0204@2 NA|NA|NA I Acyl-transferase JOKFNDED_03611 886293.Sinac_2797 1.2e-287 996.1 Planctomycetes ko:K09992 ko00000 Bacteria 2IX4V@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG3828@1,COG3828@2 NA|NA|NA C COG2133 Glucose sorbosone dehydrogenases JOKFNDED_03612 1403819.BATR01000168_gene5797 2.6e-15 89.0 Verrucomicrobia Bacteria 28T9X@1,2ZFII@2,46WJ4@74201 NA|NA|NA JOKFNDED_03615 344747.PM8797T_06060 4.9e-148 531.9 Planctomycetes Bacteria 2IXJ0@203682,COG0673@1,COG0673@2 NA|NA|NA S and related JOKFNDED_03616 1403819.BATR01000039_gene1160 2.9e-25 122.9 Verrucomicrobia Bacteria 46V4J@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03617 1396418.BATQ01000125_gene5093 9.6e-64 250.8 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_03618 497964.CfE428DRAFT_6556 1.5e-94 352.8 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity JOKFNDED_03619 1403819.BATR01000099_gene3304 2.1e-161 575.5 Verrucomicrobia ko:K16033 ko01051,ko01052,ko01130,map01051,map01052,map01130 R09851 RC01363 ko00000,ko00001 Bacteria 46U5W@74201,COG0644@1,COG0644@2 NA|NA|NA C Tryptophan halogenase JOKFNDED_03621 243090.RB5637 5.2e-82 311.2 Planctomycetes 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 2IY93@203682,COG3622@1,COG3622@2 NA|NA|NA G Belongs to the hyi family JOKFNDED_03622 240016.ABIZ01000001_gene3841 1.3e-97 363.6 Bacteria Bacteria COG0673@1,COG0673@2 NA|NA|NA S inositol 2-dehydrogenase activity JOKFNDED_03624 1123400.KB904788_gene199 1e-31 143.7 Bacteria ko:K16922 ko00000,ko01002 Bacteria COG1994@1,COG1994@2 NA|NA|NA S metallopeptidase activity JOKFNDED_03625 1403819.BATR01000138_gene4900 2.4e-289 1001.5 Verrucomicrobiae ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2IWMD@203494,46U3B@74201,COG2304@1,COG2304@2,COG5426@1,COG5426@2 NA|NA|NA S Putative glutamine amidotransferase JOKFNDED_03626 1396418.BATQ01000085_gene1092 2e-128 466.5 Verrucomicrobia Bacteria 46WAG@74201,COG2304@1,COG2304@2 NA|NA|NA S Aerotolerance regulator N-terminal JOKFNDED_03627 240016.ABIZ01000001_gene3419 1.7e-104 386.0 Verrucomicrobia Bacteria 46VTM@74201,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 JOKFNDED_03629 1396418.BATQ01000085_gene1089 2.7e-122 445.3 Verrucomicrobia ko:K03924 ko00000,ko01000 Bacteria 46UWS@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_03630 1396418.BATQ01000085_gene1088 3.1e-52 213.4 Verrucomicrobia Bacteria 29WV5@1,30IGN@2,46WIW@74201 NA|NA|NA JOKFNDED_03633 497964.CfE428DRAFT_6361 8.8e-25 119.8 Verrucomicrobia Bacteria 2FICZ@1,34A57@2,46W7Z@74201 NA|NA|NA JOKFNDED_03634 1396418.BATQ01000157_gene2425 4.7e-88 331.3 Verrucomicrobia 1.12.98.1 ko:K00441 ko00680,ko01100,ko01120,map00680,map01100,map01120 R03025 RC02628 ko00000,ko00001,ko01000 Bacteria 46TI2@74201,COG1146@1,COG1146@2 NA|NA|NA C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions JOKFNDED_03635 344747.PM8797T_01034 2.1e-184 652.1 Planctomycetes Bacteria 2J209@203682,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity JOKFNDED_03636 204773.HEAR0393 1.4e-83 316.2 Betaproteobacteria focA ko:K06212,ko:K21993 ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 Bacteria 1MU0W@1224,2VKMF@28216,COG2116@1,COG2116@2 NA|NA|NA P Formate nitrite JOKFNDED_03637 1403819.BATR01000053_gene1617 2.7e-178 631.7 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03638 1123508.JH636446_gene6208 2e-183 649.8 Planctomycetes Bacteria 2IXZ4@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_03639 1403819.BATR01000053_gene1616 3.3e-52 211.8 Verrucomicrobiae lutR_1 ko:K03710,ko:K05799 ko00000,ko03000 Bacteria 2IUYG@203494,46Z30@74201,COG2186@1,COG2186@2 NA|NA|NA K FCD JOKFNDED_03640 1403819.BATR01000066_gene1961 1.7e-49 203.0 Verrucomicrobia nlpI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944 ko:K05803 ko00000 Bacteria 46WU1@74201,COG4785@1,COG4785@2 NA|NA|NA S May be involved in cell division JOKFNDED_03642 1144275.COCOR_06769 2.6e-33 149.8 Myxococcales 3.4.21.4 ko:K01312 ko04080,ko04972,ko04974,ko05164,map04080,map04972,map04974,map05164 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 1RIHF@1224,2WPTD@28221,2YU19@29,42STC@68525,COG5640@1,COG5640@2 NA|NA|NA O Trypsin-like serine protease JOKFNDED_03643 240016.ABIZ01000001_gene5462 3.4e-112 412.1 Verrucomicrobiae Bacteria 2IVCR@203494,46U95@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03645 536019.Mesop_2338 6.2e-08 65.5 Alphaproteobacteria Bacteria 1R3Q7@1224,2UFEG@28211,COG3779@1,COG3779@2 NA|NA|NA S Protein conserved in bacteria JOKFNDED_03646 926549.KI421517_gene1530 2.5e-74 285.8 Cytophagia Bacteria 47JNX@768503,4NEN5@976,COG0673@1,COG0673@2 NA|NA|NA S PFAM Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03647 344747.PM8797T_18991 6.2e-10 70.5 Planctomycetes Bacteria 2IWX9@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins JOKFNDED_03648 1396141.BATP01000059_gene2586 4.5e-10 69.7 Verrucomicrobiae Bacteria 2BJR1@1,2IV0B@203494,32E2W@2,46X8H@74201 NA|NA|NA JOKFNDED_03649 1396141.BATP01000059_gene2585 3.3e-56 225.3 Verrucomicrobiae rluF GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2IUBZ@203494,46SWQ@74201,COG1187@1,COG1187@2 NA|NA|NA J RNA pseudouridylate synthase JOKFNDED_03651 530564.Psta_2542 7.6e-60 238.0 Planctomycetes Bacteria 2IXXG@203682,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_03652 756067.MicvaDRAFT_1405 5.8e-68 264.2 Oscillatoriales Bacteria 1GQ94@1117,1HI46@1150,COG4798@1,COG4798@2 NA|NA|NA S Methyltransferase domain JOKFNDED_03653 243090.RB9982 1.2e-53 217.6 Planctomycetes Bacteria 2IX0C@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03654 1396141.BATP01000005_gene6025 5.3e-130 471.1 Verrucomicrobiae tetA ko:K08151,ko:K08153 M00668,M00717 ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8 Bacteria 2IVGB@203494,46XCQ@74201,COG0477@1,COG2814@2 NA|NA|NA EGP MFS_1 like family JOKFNDED_03655 1396141.BATP01000025_gene980 2.5e-59 235.3 Verrucomicrobia Bacteria 46V5W@74201,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon JOKFNDED_03656 1396141.BATP01000025_gene978 7.2e-58 231.9 Bacteria 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG5002@1,COG5002@2 NA|NA|NA T protein histidine kinase activity JOKFNDED_03658 1403819.BATR01000011_gene418 4.3e-299 1033.9 Verrucomicrobiae Bacteria 2ITXB@203494,46YYY@74201,COG2931@1,COG2931@2,COG5267@1,COG5267@2 NA|NA|NA Q Protein of unknown function (DUF1800) JOKFNDED_03659 1396418.BATQ01000179_gene3136 1.1e-179 636.3 Verrucomicrobiae Bacteria 2ITT0@203494,46YXZ@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03661 134676.ACPL_3043 4.7e-07 62.8 Micromonosporales Bacteria 2I2T4@201174,4D8TV@85008,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane JOKFNDED_03662 1123070.KB899256_gene2170 2.4e-49 201.8 Verrucomicrobiae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 2IU77@203494,46TAA@74201,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes JOKFNDED_03663 1396141.BATP01000061_gene4484 3.3e-18 98.6 Verrucomicrobiae Bacteria 28XDJ@1,2IUQ4@203494,2ZJBA@2,46WSJ@74201 NA|NA|NA JOKFNDED_03664 1396418.BATQ01000106_gene5317 5.6e-37 160.2 Verrucomicrobiae hit ko:K02503 ko00000,ko04147 Bacteria 2IUKK@203494,46SZ4@74201,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain JOKFNDED_03665 344747.PM8797T_27759 0.0 1106.3 Planctomycetes Bacteria 2IZ9T@203682,COG3119@1,COG3119@2 NA|NA|NA P Domain of unknown function (DUF4976) JOKFNDED_03666 425104.Ssed_3642 1.4e-54 219.5 Gammaproteobacteria Bacteria 1RBSG@1224,1S31D@1236,COG3911@1,COG3911@2 NA|NA|NA S AAA domain JOKFNDED_03667 1396418.BATQ01000137_gene3883 8.5e-140 503.4 Verrucomicrobiae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2ITN6@203494,46S52@74201,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates JOKFNDED_03668 1123070.KB899251_gene717 2.7e-35 154.8 Verrucomicrobiae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUE5@203494,46TC9@74201,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 JOKFNDED_03669 1403819.BATR01000145_gene4956 6.1e-23 114.0 Verrucomicrobiae mauE Bacteria 2IWGT@203494,46WSE@74201,COG2259@1,COG2259@2 NA|NA|NA S Methylamine utilisation protein MauE JOKFNDED_03670 1396418.BATQ01000127_gene2548 1.3e-150 539.7 Verrucomicrobiae glcF ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001 Bacteria 2IUWH@203494,46SAS@74201,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain JOKFNDED_03671 1396418.BATQ01000127_gene2549 2.7e-178 631.7 Verrucomicrobiae glcD 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 iYO844.BSU28680 Bacteria 2IVC9@203494,46S85@74201,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain JOKFNDED_03672 1123070.KB899248_gene26 1e-118 433.7 Verrucomicrobiae htpX_2 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 2ITNF@203494,46TVV@74201,COG0501@1,COG0501@2 NA|NA|NA O CAAX prenyl protease N-terminal, five membrane helices JOKFNDED_03674 865937.Gilli_0853 5.3e-146 524.2 Gillisia 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 1HZW9@117743,2P7NJ@244698,4NEK6@976,COG0446@1,COG0446@2 NA|NA|NA S Pyridine nucleotide-disulphide oxidoreductase JOKFNDED_03675 1121875.KB907546_gene2718 1.7e-24 118.6 Flavobacteriia dsrC 1.8.5.4 ko:K11179,ko:K17218 ko00920,ko04122,map00920,map04122 R10152 RC03155 ko00000,ko00001,ko01000,ko03016 Bacteria 1I46G@117743,4NSKM@976,COG2920@1,COG2920@2 NA|NA|NA P DsrC like protein JOKFNDED_03676 382464.ABSI01000011_gene2927 1e-50 206.5 Bacteria perX Bacteria COG2210@1,COG2210@2 NA|NA|NA P Belongs to the sulfur carrier protein TusA family JOKFNDED_03678 28444.JODQ01000018_gene7229 7.3e-81 307.4 Streptosporangiales 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSN@201174,4EHBQ@85012,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family JOKFNDED_03679 1121106.JQKB01000079_gene2935 7.2e-105 387.5 Rhodospirillales deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 iLF82_1304.LF82_0465,iNRG857_1313.NRG857_22165 Bacteria 1MVN8@1224,2JQF5@204441,2TRMP@28211,COG1015@1,COG1015@2 NA|NA|NA G Metalloenzyme superfamily JOKFNDED_03680 314230.DSM3645_11242 2.3e-74 285.8 Planctomycetes Bacteria 2IXKN@203682,COG1520@1,COG1520@2 NA|NA|NA S COG1520 FOG WD40-like repeat JOKFNDED_03682 497964.CfE428DRAFT_5968 9.6e-21 106.7 Verrucomicrobia yacP ko:K06962 ko00000 Bacteria 46T34@74201,COG3688@1,COG3688@2 NA|NA|NA S YacP-like NYN domain JOKFNDED_03683 1396141.BATP01000060_gene4757 5.3e-57 228.8 Verrucomicrobiae bztC ko:K09971 ko02010,map02010 M00232 ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 Bacteria 2IWQX@203494,46ZA5@74201,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation JOKFNDED_03684 203122.Sde_3932 9e-89 334.0 Alteromonadaceae ko:K07089 ko00000 Bacteria 1MUN8@1224,1RSPM@1236,465Z2@72275,COG0701@1,COG0701@2 NA|NA|NA S Predicted permease JOKFNDED_03685 1396141.BATP01000039_gene1434 4.3e-55 221.1 Verrucomicrobiae Bacteria 2IVYW@203494,46VWV@74201,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain JOKFNDED_03686 1396418.BATQ01000099_gene5567 4.1e-112 411.8 Verrucomicrobia Bacteria 46U6I@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_03687 1356852.N008_10420 1.2e-30 139.8 Cytophagia sixA ko:K08296 ko00000,ko01000 Bacteria 47R7I@768503,4NQFM@976,COG2062@1,COG2062@2 NA|NA|NA T PFAM Phosphoglycerate mutase JOKFNDED_03690 909613.UO65_3666 6.3e-07 61.2 Pseudonocardiales Bacteria 2B0K8@1,2GRC0@201174,31SXX@2,4ED70@85010 NA|NA|NA JOKFNDED_03692 1463854.JOHT01000031_gene6841 5.8e-08 64.7 Actinobacteria Bacteria 2B0K8@1,2GRC0@201174,31SXX@2 NA|NA|NA JOKFNDED_03693 1396141.BATP01000028_gene2382 3e-49 201.8 Verrucomicrobiae cymR ko:K13643 ko00000,ko03000 Bacteria 2IVTS@203494,46SPI@74201,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator JOKFNDED_03694 1396141.BATP01000040_gene2129 4e-57 228.4 Verrucomicrobiae amj Bacteria 28NMK@1,2IVQP@203494,2ZBN3@2,46URV@74201 NA|NA|NA U Pfam:DUF2837 JOKFNDED_03695 1396141.BATP01000003_gene5001 5.5e-23 113.6 Verrucomicrobiae Bacteria 2DKJX@1,2IV07@203494,309RR@2,46ZIG@74201 NA|NA|NA S Putative prokaryotic signal transducing protein JOKFNDED_03696 1396141.BATP01000001_gene5409 1.4e-83 317.8 Verrucomicrobiae ko:K11935 ko02026,map02026 ko00000,ko00001 Bacteria 2IV1D@203494,46Z9N@74201,COG4783@1,COG4783@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03697 1396141.BATP01000039_gene1447 1.2e-50 207.2 Verrucomicrobiae Bacteria 2IVV8@203494,46USU@74201,COG4319@1,COG4319@2 NA|NA|NA S ketosteroid isomerase JOKFNDED_03698 497964.CfE428DRAFT_1509 6.9e-108 397.5 Bacteria Bacteria COG1680@1,COG1680@2 NA|NA|NA V peptidase activity JOKFNDED_03699 870187.Thini_3671 7.4e-11 72.8 Gammaproteobacteria Bacteria 1NE25@1224,1SIBM@1236,2E8K6@1,332XV@2 NA|NA|NA JOKFNDED_03700 335541.Swol_1570 2.9e-24 118.2 Clostridia Bacteria 1V7GS@1239,24JFR@186801,COG5573@1,COG5573@2 NA|NA|NA S PFAM PilT protein domain protein JOKFNDED_03702 497964.CfE428DRAFT_3412 2.5e-171 608.6 Verrucomicrobia gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 46SCM@74201,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) JOKFNDED_03703 1123070.KB899247_gene1466 1.4e-17 95.5 Verrucomicrobiae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 2IURF@203494,46WBS@74201,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) JOKFNDED_03704 1396141.BATP01000059_gene2470 1.3e-151 542.7 Verrucomicrobiae nirH Bacteria 2IU3G@203494,46SDK@74201,COG1522@1,COG1522@2 NA|NA|NA K sequence-specific DNA binding JOKFNDED_03705 1396418.BATQ01000046_gene6112 1.3e-67 263.5 Bacteria fprA1 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria COG0491@1,COG0491@2 NA|NA|NA GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid JOKFNDED_03707 349741.Amuc_0319 1.2e-134 486.9 Verrucomicrobiae der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2ITU6@203494,46SJY@74201,COG1160@1,COG1160@2 NA|NA|NA S KH-domain-like of EngA bacterial GTPase enzymes, C-terminal JOKFNDED_03708 497964.CfE428DRAFT_2007 9e-38 163.7 Verrucomicrobia pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 46T66@74201,COG0558@1,COG0558@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase JOKFNDED_03711 497964.CfE428DRAFT_3097 2.8e-23 115.2 Verrucomicrobia Bacteria 46VTX@74201,COG1510@1,COG1510@2 NA|NA|NA K regulation of RNA biosynthetic process JOKFNDED_03712 240016.ABIZ01000001_gene2 7.7e-113 413.7 Verrucomicrobiae fcl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042350,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046368,GO:0046483,GO:0050577,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.271,4.2.1.47 ko:K01711,ko:K02377,ko:K16554 ko00051,ko00520,ko01100,ko05111,map00051,map00520,map01100,map05111 R00888,R05692 RC00402,RC01014 ko00000,ko00001,ko01000,ko02000 8.A.3.1 iECP_1309.ECP_2092,iLF82_1304.LF82_0626,iNRG857_1313.NRG857_10435,iUMNK88_1353.UMNK88_2597 Bacteria 2ITY4@203494,46SD9@74201,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction JOKFNDED_03713 679937.Bcop_1851 5.3e-139 500.7 Bacteroidaceae gmd 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 R00888 RC00402 ko00000,ko00001,ko01000 Bacteria 2FMUP@200643,4AKHE@815,4NEB6@976,COG1089@1,COG1089@2 NA|NA|NA M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose JOKFNDED_03715 1403819.BATR01000185_gene6411 6.6e-110 403.7 Verrucomicrobiae rfbF 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 R00956 RC00002 ko00000,ko00001,ko01000 Bacteria 2IVN8@203494,46SQS@74201,COG1208@1,COG1208@2 NA|NA|NA JM Nucleotidyl transferase JOKFNDED_03716 1403819.BATR01000185_gene6410 2e-128 465.7 Verrucomicrobia rfbG 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 46UP7@74201,COG0451@1,COG0451@2 NA|NA|NA GM Polysaccharide biosynthesis protein JOKFNDED_03717 102232.GLO73106DRAFT_00021490 3.2e-50 204.9 Cyanobacteria rfbC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008830,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1G64W@1117,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose JOKFNDED_03718 1268072.PSAB_18940 6.7e-48 198.0 Paenibacillaceae 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1U0H5@1239,27210@186822,4I9VC@91061,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein JOKFNDED_03719 1166018.FAES_5463 1.1e-69 270.0 Bacteroidetes GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006029,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0030166,GO:0030203,GO:0030204,GO:0030206,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044272,GO:0044281,GO:0044464,GO:0050650,GO:0050654,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510 Bacteria 4NZP6@976,COG3510@1,COG3510@2 NA|NA|NA V Cephalosporin hydroxylase JOKFNDED_03720 330214.NIDE3429 1.9e-70 272.7 Bacteria ko:K05303 ko00000,ko01000 Bacteria COG4122@1,COG4122@2 NA|NA|NA E O-methyltransferase activity JOKFNDED_03721 314345.SPV1_07536 1.5e-13 84.0 Bacteria Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 JOKFNDED_03722 935557.ATYB01000008_gene5983 1.6e-38 166.0 Rhizobiaceae Bacteria 1RDPU@1224,2U872@28211,4BF0H@82115,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) JOKFNDED_03723 272134.KB731324_gene5125 2.4e-25 123.2 Oscillatoriales Bacteria 1G4QA@1117,1HBPT@1150,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 JOKFNDED_03724 1509405.GV67_19485 9.2e-118 430.3 Rhizobiaceae bplA 1.1.1.335 ko:K13020 ko00520,map00520 R10140 RC00182 ko00000,ko00001,ko01000,ko01005 Bacteria 1MUP0@1224,2VF2U@28211,4BMCM@82115,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain JOKFNDED_03725 1038862.KB893833_gene4733 2.8e-58 231.5 Bradyrhizobiaceae 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1QWJD@1224,2TWZD@28211,3JYB2@41294,COG1045@1,COG1045@2 NA|NA|NA E Hexapeptide repeat of succinyl-transferase JOKFNDED_03726 1509405.GV67_19495 2.1e-130 472.2 Rhizobiaceae Bacteria 1MUPN@1224,2TRIQ@28211,4BA1X@82115,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family JOKFNDED_03727 491916.RHECIAT_CH0000845 6.9e-44 184.9 Rhizobiaceae ko:K06320,ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1R62R@1224,2TVHD@28211,4BJ9Z@82115,COG4641@1,COG4641@2 NA|NA|NA S Glycosyl transferases group 1 JOKFNDED_03728 243090.RB2502 1.2e-40 173.3 Planctomycetes 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 2J17A@203682,COG0110@1,COG0110@2 NA|NA|NA S PFAM Bacterial transferase hexapeptide (three repeats) JOKFNDED_03729 1121481.AUAS01000011_gene5136 1.9e-50 206.5 Bacteria ubiE1 Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase JOKFNDED_03730 1173263.Syn7502_03251 1.1e-75 290.0 Cyanobacteria ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1GQEW@1117,COG2227@1,COG2227@2 NA|NA|NA H Methylase involved in ubiquinone menaquinone biosynthesis JOKFNDED_03731 1223410.KN050846_gene2746 4e-40 171.8 Bacteroidetes Bacteria 4NV0U@976,COG2242@1,COG2242@2 NA|NA|NA H TIGRFAM methyltransferase FkbM family JOKFNDED_03732 497964.CfE428DRAFT_3083 2.7e-57 229.2 Verrucomicrobia 4.2.1.46,5.1.3.2 ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 46SJG@74201,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase JOKFNDED_03733 882.DVU_2995 3.1e-58 232.6 Desulfovibrionales Bacteria 1PEGM@1224,2MH8Z@213115,2WURM@28221,42Y7E@68525,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 JOKFNDED_03734 1286631.X805_32750 1.5e-39 170.2 Betaproteobacteria GO:0003674,GO:0003824,GO:0016740,GO:0016757 Bacteria 1RB30@1224,2VVJ1@28216,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase family 2 JOKFNDED_03735 111781.Lepto7376_1604 1.4e-58 233.0 Oscillatoriales Bacteria 1G6S8@1117,1HGG7@1150,COG0457@1,COG0457@2 NA|NA|NA S Sulfotransferase family JOKFNDED_03736 391612.CY0110_00335 9.8e-25 120.9 Cyanothece Bacteria 1G7C5@1117,3KIQY@43988,COG0457@1,COG0457@2 NA|NA|NA S Putative capsular polysaccharide synthesis protein JOKFNDED_03737 404589.Anae109_1239 1.5e-12 80.5 Proteobacteria Bacteria 1N3TN@1224,COG1216@1,COG1216@2 NA|NA|NA Q Pfam Glycosyl transferase family 2 JOKFNDED_03738 398579.Spea_1412 9.3e-56 223.8 Shewanellaceae tuaG GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.305 ko:K16698,ko:K21363 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1RA3F@1224,1T24F@1236,2QD4X@267890,COG0463@1,COG0463@2 NA|NA|NA M PFAM glycosyl transferase family 2 JOKFNDED_03739 935840.JAEQ01000005_gene1107 2.9e-48 199.1 Phyllobacteriaceae wbpV 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX2J@1224,2TVNU@28211,43KKC@69277,COG0451@1,COG0451@2 NA|NA|NA GM RmlD substrate binding domain JOKFNDED_03740 1429916.X566_17585 2.2e-54 218.8 Bradyrhizobiaceae wbfU ko:K13012 ko00000,ko01005 Bacteria 1R4J5@1224,2U77V@28211,3K42N@41294,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase JOKFNDED_03741 313628.LNTAR_14482 1.3e-124 453.8 Bacteria capD GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 4.2.1.115,4.2.1.135,4.2.1.46 ko:K01710,ko:K15894,ko:K15912,ko:K19421 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R06513,R09697 RC00402,RC02609 ko00000,ko00001,ko00002,ko01000 Bacteria COG1086@1,COG1086@2 NA|NA|NA GM Polysaccharide biosynthesis protein JOKFNDED_03742 862908.BMS_0329 5.6e-29 135.6 Bdellovibrionales ko:K02847 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 Bacteria 1NGAP@1224,2MTE8@213481,2WSRN@28221,42XF9@68525,COG3307@1,COG3307@2 NA|NA|NA M O-antigen ligase like membrane protein JOKFNDED_03743 1403819.BATR01000167_gene5717 1.7e-235 822.8 Verrucomicrobiae yhjJ ko:K07263 ko00000,ko01000,ko01002 Bacteria 2ITM2@203494,46UTT@74201,COG0612@1,COG0612@2 NA|NA|NA S Insulinase (Peptidase family M16) JOKFNDED_03746 1449976.KALB_6599 2.2e-45 188.7 Actinobacteria Bacteria 2AAUU@1,2GVX0@201174,3107N@2 NA|NA|NA S Psort location CytoplasmicMembrane, score JOKFNDED_03747 583355.Caka_2001 1.3e-92 346.3 Verrucomicrobia hisA GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 Bacteria 46U39@74201,COG0106@1,COG0106@2 NA|NA|NA E Histidine biosynthesis protein JOKFNDED_03748 1396141.BATP01000003_gene5098 1.6e-63 250.0 Bacteria exoO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K16555,ko:K16564 ko00000,ko01000,ko01003 GT2 Bacteria COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_03749 1396418.BATQ01000015_gene4326 1.2e-36 159.8 Verrucomicrobiae ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2IUP1@203494,46SZS@74201,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance JOKFNDED_03750 1403819.BATR01000052_gene1575 1.9e-119 435.6 Verrucomicrobiae prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 2ITT3@203494,46SVH@74201,COG0462@1,COG0462@2 NA|NA|NA EF Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) JOKFNDED_03751 357808.RoseRS_4588 2.1e-24 119.8 Bacteria speE 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria COG0421@1,COG0421@2 NA|NA|NA E spermidine synthase activity JOKFNDED_03752 522306.CAP2UW1_1108 5.1e-78 298.5 unclassified Betaproteobacteria Bacteria 1KQ8J@119066,1NRP8@1224,2VGZQ@28216,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_03753 349741.Amuc_0963 3.9e-98 365.2 Verrucomicrobiae GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K01990,ko:K01992,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2ITQM@203494,46SII@74201,COG1131@1,COG1131@2,COG1668@1,COG1668@2 NA|NA|NA V ABC-2 type transporter JOKFNDED_03754 1121930.AQXG01000001_gene1391 3.5e-51 208.4 Bacteroidetes trmH 2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 4NFH3@976,COG0566@1,COG0566@2 NA|NA|NA J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA JOKFNDED_03755 1540221.JQNI01000002_gene2457 1.7e-113 416.8 Bacteria ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria COG1132@1,COG1132@2 NA|NA|NA V (ABC) transporter JOKFNDED_03757 1210884.HG799465_gene11798 5.6e-135 487.6 Planctomycetes Bacteria 2IYJ1@203682,COG1520@1,COG1520@2 NA|NA|NA S beta-propeller repeat JOKFNDED_03758 1210884.HG799464_gene10712 5.7e-44 183.3 Planctomycetes Bacteria 2J4YY@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03759 1396418.BATQ01000020_gene5017 5.3e-44 185.3 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_03760 1087481.AGFX01000038_gene1398 2e-14 86.3 Paenibacillaceae M1-418 Bacteria 1VNTH@1239,26STP@186822,4HUFV@91061,COG1714@1,COG1714@2 NA|NA|NA S RDD family JOKFNDED_03761 382464.ABSI01000011_gene2741 0.0 1334.7 Bacteria 4.1.1.38 ko:K20370 ko00620,ko01100,map00620,map01100 R00346 RC02741 ko00000,ko00001,ko01000 Bacteria 28HY3@1,2Z83I@2 NA|NA|NA S phosphoenolpyruvate carboxykinase (diphosphate) activity JOKFNDED_03762 497964.CfE428DRAFT_6073 3.6e-72 278.9 Verrucomicrobia GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 ko:K01448,ko:K03727 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 46SKJ@74201,COG0860@1,COG0860@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase JOKFNDED_03763 1396141.BATP01000023_gene542 7.5e-87 327.0 Verrucomicrobiae ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2ITNG@203494,46SQ2@74201,COG1692@1,COG1692@2 NA|NA|NA S YmdB-like protein JOKFNDED_03765 314232.SKA53_13218 3.7e-38 164.9 Alphaproteobacteria Bacteria 1PQTH@1224,2CHP8@1,2U4NQ@28211,2ZAVY@2 NA|NA|NA JOKFNDED_03767 1121456.ATVA01000014_gene688 3.5e-27 128.3 Desulfovibrionales 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1RHRM@1224,2M923@213115,2WQWH@28221,42UA5@68525,COG0662@1,COG0662@2 NA|NA|NA G Cupin 2, conserved barrel domain protein JOKFNDED_03768 583355.Caka_1331 1.8e-82 312.8 Opitutae ko:K08978 ko00000,ko02000 2.A.7.2 Bacteria 3K7WV@414999,46UXU@74201,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family JOKFNDED_03769 272123.Anacy_5223 1.2e-39 170.2 Nostocales Bacteria 1GJMC@1117,1HS2C@1161,2BK59@1,32EIW@2 NA|NA|NA JOKFNDED_03770 756272.Plabr_1365 1.5e-309 1068.9 Planctomycetes Bacteria 2IYDW@203682,COG2010@1,COG2010@2 NA|NA|NA C Concanavalin A-like lectin/glucanases superfamily JOKFNDED_03772 1396141.BATP01000022_gene309 4e-87 328.6 Verrucomicrobiae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2ITTD@203494,46TMY@74201,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V JOKFNDED_03773 1396418.BATQ01000009_gene3850 3.8e-231 808.5 Verrucomicrobiae Bacteria 2IU13@203494,46URY@74201,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation JOKFNDED_03774 1403819.BATR01000021_gene721 5.8e-11 75.5 Verrucomicrobia Bacteria 2F0SU@1,33TUW@2,46V1J@74201 NA|NA|NA JOKFNDED_03775 1396418.BATQ01000009_gene3852 6.6e-105 387.5 Verrucomicrobiae Bacteria 2IWMN@203494,46UN0@74201,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase JOKFNDED_03776 240016.ABIZ01000001_gene5789 9.7e-81 308.9 Verrucomicrobiae Bacteria 2IWE7@203494,46UYI@74201,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like JOKFNDED_03777 497964.CfE428DRAFT_5746 6e-117 427.6 Verrucomicrobia fbpC 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 Bacteria 46SFH@74201,COG3842@1,COG3842@2 NA|NA|NA E ATPases associated with a variety of cellular activities JOKFNDED_03778 1396418.BATQ01000137_gene3885 1.4e-136 493.4 Verrucomicrobiae ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 2IU08@203494,46SF5@74201,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein JOKFNDED_03780 344747.PM8797T_27250 5.5e-207 727.6 Planctomycetes 4.2.2.23 ko:K18195 ko00000,ko01000 PL4 Bacteria 2IXDY@203682,COG3356@1,COG3356@2,COG4625@1,COG4625@2 NA|NA|NA G lyase activity JOKFNDED_03781 756272.Plabr_3084 0.0 1185.6 Planctomycetes 1.1.2.6 ko:K05889,ko:K09992,ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R03136,R10151 RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 Bacteria 2IX6X@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2,COG2863@1,COG2863@2 NA|NA|NA C Membrane-bound dehydrogenase domain protein JOKFNDED_03782 452637.Oter_0661 9.5e-39 166.4 Opitutae Bacteria 29XGP@1,30J79@2,3K9V9@414999,46XI5@74201 NA|NA|NA S Domain of unknown function (DUF5069) JOKFNDED_03783 1121918.ARWE01000001_gene2610 2e-89 336.7 Desulfuromonadales ko:K18903 M00698 ko00000,ko00002,ko01504,ko02000 1.B.17.3.3 Bacteria 1MUA8@1224,2WJXF@28221,42NKZ@68525,43T58@69541,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_03784 452637.Oter_3813 1.4e-180 639.4 Opitutae mexF ko:K18299,ko:K18902,ko:K19585 M00641,M00698,M00767 ko00000,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.16,2.A.6.2.47 Bacteria 3K72W@414999,46U0U@74201,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family JOKFNDED_03786 511.JT27_14210 2.5e-11 75.5 Alcaligenaceae cccA Bacteria 1RKH6@1224,2VQE8@28216,3T3ZE@506,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III JOKFNDED_03787 518766.Rmar_2664 1.4e-17 95.9 Bacteria ko:K04752 ko00000 Bacteria COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family JOKFNDED_03788 1111069.TCCBUS3UF1_7720 1e-91 343.6 Deinococcus-Thermus ko:K07086 ko00000 Bacteria 1WJER@1297,COG3329@1,COG3329@2 NA|NA|NA S Na+-dependent bicarbonate transporter superfamily JOKFNDED_03789 1121377.KB906401_gene3551 2.7e-25 121.3 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity JOKFNDED_03790 344747.PM8797T_00157 5.6e-144 518.1 Planctomycetes Bacteria 2J1S4@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_03791 497964.CfE428DRAFT_3424 6.8e-11 73.6 Bacteria rtxA GO:0000166,GO:0000287,GO:0000822,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005576,GO:0006464,GO:0006508,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0008233,GO:0008234,GO:0009405,GO:0009987,GO:0010467,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0019835,GO:0019836,GO:0020002,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030554,GO:0031640,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033644,GO:0035639,GO:0035821,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043178,GO:0043412,GO:0043624,GO:0043657,GO:0043933,GO:0044003,GO:0044004,GO:0044179,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044279,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046872,GO:0051261,GO:0051604,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K10953,ko:K20276 ko02024,ko05110,map02024,map05110 ko00000,ko00001,ko02042 Bacteria COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity JOKFNDED_03793 1545915.JROG01000001_gene577 1.4e-79 303.1 Sphingomonadales ko:K07052 ko00000 Bacteria 1RCTR@1224,2KE4U@204457,2VGN5@28211,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity JOKFNDED_03794 288000.BBta_3181 2.9e-106 391.7 Alphaproteobacteria ko:K07052 ko00000 Bacteria 1RCTR@1224,2VGN5@28211,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity JOKFNDED_03795 243231.GSU2508 7.6e-11 75.9 Deltaproteobacteria Bacteria 1NNJ6@1224,2WKWJ@28221,42PBD@68525,COG0457@1,COG0457@2 NA|NA|NA M Tetratricopeptide TPR_2 repeat protein JOKFNDED_03797 1128427.KB904821_gene2717 4.1e-88 331.6 Oscillatoriales Bacteria 1G5AX@1117,1HAQ7@1150,28KU8@1,2ZCM9@2 NA|NA|NA S STELLO glycosyltransferases JOKFNDED_03801 1247963.JPHU01000001_gene2030 5.5e-62 244.6 Alphaproteobacteria ko:K07480 ko00000 Bacteria 1MV8R@1224,2TURN@28211,COG1662@1,COG1662@2 NA|NA|NA L PFAM IS1 transposase JOKFNDED_03807 497964.CfE428DRAFT_3424 1.4e-28 132.9 Bacteria rtxA GO:0000166,GO:0000287,GO:0000822,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005576,GO:0006464,GO:0006508,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0008233,GO:0008234,GO:0009405,GO:0009987,GO:0010467,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0019835,GO:0019836,GO:0020002,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030554,GO:0031640,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033644,GO:0035639,GO:0035821,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043178,GO:0043412,GO:0043624,GO:0043657,GO:0043933,GO:0044003,GO:0044004,GO:0044179,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044279,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046872,GO:0051261,GO:0051604,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K10953,ko:K20276 ko02024,ko05110,map02024,map05110 ko00000,ko00001,ko02042 Bacteria COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity JOKFNDED_03808 1403819.BATR01000176_gene5944 1.2e-10 72.4 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_03809 1123508.JH636440_gene2248 8e-19 100.1 Bacteria Bacteria 2E1Y1@1,32X6X@2 NA|NA|NA JOKFNDED_03810 658086.HMPREF0994_06434 2.8e-51 210.3 Firmicutes Bacteria 1VSII@1239,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity JOKFNDED_03811 13035.Dacsa_3616 8.6e-16 89.4 Cyanobacteria Bacteria 1G9XY@1117,COG1724@1,COG1724@2 NA|NA|NA N HicA toxin of bacterial toxin-antitoxin, JOKFNDED_03812 300852.55771613 5.2e-13 80.5 Deinococcus-Thermus Bacteria 1WKES@1297,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 JOKFNDED_03813 1403819.BATR01000045_gene1321 1.6e-67 263.1 Verrucomicrobiae Bacteria 2IVXF@203494,46XHD@74201,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family JOKFNDED_03814 240016.ABIZ01000001_gene3192 3.8e-127 461.8 Verrucomicrobiae yqiK ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria 2IVCH@203494,46XBU@74201,COG2268@1,COG2268@2 NA|NA|NA S prohibitin homologues JOKFNDED_03815 278957.ABEA03000060_gene3074 5.5e-29 134.4 Opitutae Bacteria 29F7N@1,3207C@2,3K94A@414999,46XQ7@74201 NA|NA|NA JOKFNDED_03816 1403819.BATR01000163_gene5487 1.1e-18 99.8 Verrucomicrobiae Bacteria 29FC4@1,2IWG0@203494,3029T@2,46XS1@74201 NA|NA|NA JOKFNDED_03817 530564.Psta_3498 3.1e-56 226.1 Planctomycetes Bacteria 28MZ7@1,2IZSK@203682,2ZB61@2 NA|NA|NA JOKFNDED_03818 756272.Plabr_0420 3.2e-160 571.6 Planctomycetes Bacteria 2IYQY@203682,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_03819 314230.DSM3645_04530 8.3e-236 823.5 Planctomycetes Bacteria 2IXA9@203682,COG1020@1,COG1020@2 NA|NA|NA Q Protein of unknown function (DUF1587) JOKFNDED_03820 1396141.BATP01000030_gene3629 2.5e-164 585.9 Verrucomicrobiae deaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2ITPY@203494,46U0S@74201,COG0513@1,COG0513@2 NA|NA|NA L DbpA RNA binding domain JOKFNDED_03821 1403819.BATR01000181_gene6221 1.4e-77 296.2 Verrucomicrobia 3.1.1.85 ko:K19560 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria 46VVR@74201,COG0400@1,COG0400@2 NA|NA|NA S carboxylic ester hydrolase activity JOKFNDED_03822 240016.ABIZ01000001_gene4273 6.8e-43 180.3 Verrucomicrobiae Bacteria 2IUMM@203494,46VKZ@74201,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain JOKFNDED_03823 595460.RRSWK_02108 3.8e-101 375.6 Bacteria Bacteria COG3712@1,COG3712@2 NA|NA|NA PT iron ion homeostasis JOKFNDED_03824 497964.CfE428DRAFT_4423 1.6e-38 166.0 Verrucomicrobia rfaY ko:K03088 ko00000,ko03021 Bacteria 46W5Z@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 JOKFNDED_03825 530564.Psta_3090 3.6e-49 201.8 Planctomycetes cheR 2.1.1.80,2.7.13.3,3.1.1.61 ko:K10125,ko:K13924 ko02020,ko02030,map02020,map02030 M00504,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 2J540@203682,COG3829@1,COG3829@2,COG4977@1,COG4977@2 NA|NA|NA K SMART helix-turn-helix- domain containing protein AraC type JOKFNDED_03826 344747.PM8797T_16183 0.0 1164.8 Planctomycetes Bacteria 2J248@203682,COG2411@1,COG2411@2 NA|NA|NA S Planctomycete cytochrome C JOKFNDED_03827 344747.PM8797T_16178 4.7e-223 780.4 Planctomycetes Bacteria 2J1RU@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_03828 1123508.JH636441_gene3051 8.1e-165 587.4 Planctomycetes Bacteria 2IXDH@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_03829 1123508.JH636441_gene3050 6.3e-180 637.1 Planctomycetes Bacteria 2IX5I@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03831 278957.ABEA03000050_gene166 4.9e-33 147.5 Verrucomicrobia Bacteria 2DX9U@1,3441M@2,46WED@74201 NA|NA|NA JOKFNDED_03832 1156935.QWE_05488 7.8e-41 173.7 Rhizobiaceae Bacteria 1RH08@1224,2U96H@28211,4BF1E@82115,COG3631@1,COG3631@2 NA|NA|NA S SnoaL-like polyketide cyclase JOKFNDED_03833 240016.ABIZ01000001_gene3755 0.0 1117.1 Verrucomicrobiae clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2ITN7@203494,46S4S@74201,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein JOKFNDED_03836 1173024.KI912152_gene717 2.1e-27 129.8 Bacteria Bacteria 2E5MT@1,330CP@2 NA|NA|NA JOKFNDED_03840 1123070.KB899249_gene345 4.2e-94 352.1 Verrucomicrobiae Bacteria 2ITH6@203494,46TQ7@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03841 1396141.BATP01000019_gene1620 1.3e-13 83.2 Verrucomicrobiae Bacteria 293Z2@1,2IUXA@203494,2ZRE2@2,46WSD@74201 NA|NA|NA JOKFNDED_03842 1123070.KB899253_gene1111 3.5e-90 338.6 Verrucomicrobiae ko:K08642 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Bacteria 2IU1Z@203494,46V20@74201,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 JOKFNDED_03843 1396141.BATP01000036_gene3839 3.1e-56 224.9 Verrucomicrobiae Bacteria 2IW4D@203494,46VXB@74201,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_03844 1123070.KB899250_gene519 6.7e-129 467.2 Verrucomicrobiae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 2ITRY@203494,46SQW@74201,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 JOKFNDED_03845 195250.CM001776_gene3775 1.2e-13 84.0 Synechococcus Bacteria 1G3R5@1117,1H0YC@1129,COG5464@1,COG5464@2 NA|NA|NA S Protein of unknown function (DUF2887) JOKFNDED_03846 344747.PM8797T_24601 6.4e-178 630.6 Planctomycetes rbsA 3.6.3.17 ko:K10441 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2IWTU@203682,COG1129@1,COG1129@2 NA|NA|NA P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system JOKFNDED_03849 1267535.KB906767_gene5003 1.3e-85 322.8 Acidobacteria Bacteria 3Y7EK@57723,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family JOKFNDED_03850 314230.DSM3645_26339 6.9e-150 537.3 Planctomycetes Bacteria 2IYT9@203682,COG2755@1,COG2755@2 NA|NA|NA E Domain of Unknown Function (DUF1080) JOKFNDED_03851 583355.Caka_1358 3e-50 205.3 Bacteria speE 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria COG0421@1,COG0421@2 NA|NA|NA E spermidine synthase activity JOKFNDED_03852 240016.ABIZ01000001_gene2948 3.2e-11 73.9 Verrucomicrobiae Bacteria 2970V@1,2IW93@203494,2ZU9A@2,46WP4@74201 NA|NA|NA JOKFNDED_03853 880070.Cycma_4044 3.1e-148 531.2 Cytophagia Bacteria 47KBS@768503,4NK9X@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_03854 1123248.KB893381_gene1000 2e-101 375.6 Bacteroidetes Bacteria 4NK3I@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_03856 344747.PM8797T_08334 7.2e-55 220.3 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_03857 497964.CfE428DRAFT_2557 4e-151 541.2 Verrucomicrobia ssuD 1.14.14.5 ko:K04091 ko00920,map00920 R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 Bacteria 46TA4@74201,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase JOKFNDED_03858 243090.RB12599 4.8e-30 137.9 Planctomycetes ssuE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.1.38,1.5.1.45 ko:K00299,ko:K16902 ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100 R05706,R07210,R09517,R09520,R09748,R10206 RC00046,RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 iAF1260.b0937,iB21_1397.B21_00948,iBWG_1329.BWG_0789,iE2348C_1286.E2348C_0930,iECBD_1354.ECBD_2658,iECB_1328.ECB_00941,iECDH10B_1368.ECDH10B_1007,iECDH1ME8569_1439.ECDH1ME8569_0888,iECD_1391.ECD_00941,iECIAI1_1343.ECIAI1_0978,iECO103_1326.ECO103_0982,iECW_1372.ECW_m1047,iEKO11_1354.EKO11_2893,iETEC_1333.ETEC_1005,iEcDH1_1363.EcDH1_2706,iEcE24377_1341.EcE24377A_1052,iEcHS_1320.EcHS_A1046,iEcolC_1368.EcolC_2659,iJO1366.b0937,iSB619.SA_RS01880,iSbBS512_1146.SbBS512_E2381,iUMNK88_1353.UMNK88_1092,iWFL_1372.ECW_m1047,iY75_1357.Y75_RS04870 Bacteria 2J0CB@203682,COG0431@1,COG0431@2 NA|NA|NA S Flavodoxin-like fold JOKFNDED_03859 497964.CfE428DRAFT_2554 4.3e-109 401.7 Verrucomicrobia Bacteria 46UJ9@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_03860 756272.Plabr_1060 1e-144 520.0 Bacteria Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily JOKFNDED_03861 240016.ABIZ01000001_gene950 7.3e-46 191.4 Verrucomicrobiae Bacteria 2IWMR@203494,46U6S@74201,COG1940@1,COG1940@2 NA|NA|NA GK ROK family JOKFNDED_03862 1396141.BATP01000027_gene1055 0.0 1486.9 Verrucomicrobiae acnA 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2ITHS@203494,46SFS@74201,COG1048@1,COG1048@2 NA|NA|NA C Aconitase C-terminal domain JOKFNDED_03863 1041139.KB902578_gene5252 5.9e-63 248.1 Rhizobiaceae 4.2.2.3 ko:K01729,ko:K12287 ko00051,map00051 R03706 ko00000,ko00001,ko01000,ko02044 Bacteria 1R9ZI@1224,2UM0D@28211,4B9V1@82115,COG3420@1,COG3420@2 NA|NA|NA P Parallel beta-helix repeats JOKFNDED_03865 1123070.KB899252_gene973 3.2e-162 578.6 Verrucomicrobiae amtB ko:K03320 ko00000,ko02000 1.A.11 iJN678.amt2 Bacteria 2ITWC@203494,46SCE@74201,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family JOKFNDED_03866 240016.ABIZ01000001_gene1420 3.2e-39 168.3 Bacteria ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria COG0664@1,COG0664@2 NA|NA|NA T cyclic nucleotide binding JOKFNDED_03867 1123070.KB899247_gene1528 2.2e-284 984.9 Verrucomicrobiae Bacteria 2ITIC@203494,46YZ0@74201,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain JOKFNDED_03869 497964.CfE428DRAFT_3622 2.9e-40 171.4 Verrucomicrobia osmC ko:K07397 ko00000 Bacteria 46T1Y@74201,COG1765@1,COG1765@2 NA|NA|NA O PFAM OsmC family protein JOKFNDED_03870 1396141.BATP01000002_gene4819 5e-67 263.8 Verrucomicrobiae ko:K07277,ko:K09800 ko00000,ko02000,ko03029 1.B.33 Bacteria 2IUA9@203494,46TSK@74201,COG2911@1,COG2911@2 NA|NA|NA S TamB, inner membrane protein subunit of TAM complex JOKFNDED_03871 497964.CfE428DRAFT_3837 2.8e-91 343.2 Verrucomicrobia ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 46TFS@74201,COG4775@1,COG4775@2 NA|NA|NA M Surface antigen JOKFNDED_03872 1396141.BATP01000014_gene2761 5.2e-43 181.8 Verrucomicrobiae Bacteria 29YM6@1,2IW3G@203494,30KGM@2,46Z9P@74201 NA|NA|NA JOKFNDED_03873 1396141.BATP01000004_gene5880 4.2e-12 78.6 Verrucomicrobiae Bacteria 2BKHW@1,2IW9Q@203494,32EZ2@2,46XNP@74201 NA|NA|NA JOKFNDED_03874 1396141.BATP01000038_gene1219 5.1e-92 344.7 Verrucomicrobiae Bacteria 29ZBE@1,2IW0E@203494,30M9X@2,46XIG@74201 NA|NA|NA JOKFNDED_03875 1396141.BATP01000014_gene2757 1.7e-26 125.9 Verrucomicrobiae Bacteria 2AX3F@1,2IWDI@203494,31P1T@2,46XQJ@74201 NA|NA|NA JOKFNDED_03876 1396141.BATP01000014_gene2756 1.7e-24 119.4 Verrucomicrobiae Bacteria 2AW6J@1,2IV0I@203494,31N1K@2,46X8I@74201 NA|NA|NA JOKFNDED_03877 1403819.BATR01000051_gene1518 1e-106 394.4 Verrucomicrobiae Bacteria 2A7XF@1,2IUF2@203494,30WX8@2,46X7H@74201 NA|NA|NA JOKFNDED_03878 1396418.BATQ01000014_gene4373 3.7e-40 171.8 Verrucomicrobiae ko:K01990,ko:K15738 M00254 ko00000,ko00002,ko02000 3.A.1,3.A.1.120.6 Bacteria 2IW6M@203494,46Z4B@74201,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter JOKFNDED_03879 1396141.BATP01000022_gene425 4.9e-41 174.9 Verrucomicrobiae Bacteria 2BFFU@1,2IW4G@203494,3299I@2,46XK9@74201 NA|NA|NA JOKFNDED_03881 1396141.BATP01000022_gene427 1.1e-106 393.7 Verrucomicrobiae dotB ko:K12203 ko00000,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 2ITSV@203494,46Z49@74201,COG2805@1,COG2805@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_03882 1396141.BATP01000007_gene5640 8.3e-21 106.7 Verrucomicrobiae Bacteria 2AX59@1,2IWFV@203494,31P3N@2,46XRW@74201 NA|NA|NA JOKFNDED_03883 1403819.BATR01000112_gene3726 7.4e-18 96.3 Verrucomicrobiae pilH ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2ITWN@203494,46SHV@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_03884 497964.CfE428DRAFT_1200 3.6e-46 192.2 Verrucomicrobia pilI Bacteria 46VKD@74201,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component JOKFNDED_03885 497964.CfE428DRAFT_1199 4.3e-30 138.7 Verrucomicrobia Bacteria 46VY0@74201,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_03886 240016.ABIZ01000001_gene2405 2e-92 345.5 Verrucomicrobiae Bacteria 2ITKJ@203494,46TA5@74201,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain JOKFNDED_03887 497964.CfE428DRAFT_1197 2.3e-70 272.7 Verrucomicrobia rfaF 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K02841,ko:K02843,ko:K12982 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30,GT9 Bacteria 46T6R@74201,COG0859@1,COG0859@2 NA|NA|NA M glycosyl transferase family 9 JOKFNDED_03888 661087.HMPREF1008_00101 5.1e-49 200.7 Coriobacteriia rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GK53@201174,4CVQQ@84998,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids JOKFNDED_03889 1403819.BATR01000112_gene3741 1.2e-77 297.4 Bacteria ko:K02305,ko:K07152 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko03029 3.D.4.10 Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_03890 497964.CfE428DRAFT_3443 6.7e-66 257.3 Verrucomicrobia lolD ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 46UQZ@74201,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of JOKFNDED_03891 1123487.KB892863_gene1961 8.7e-19 100.1 Rhodocyclales Bacteria 1NDT4@1224,2DPY2@1,2KXQT@206389,2WC4I@28216,333WA@2 NA|NA|NA S AP2 domain JOKFNDED_03892 497964.CfE428DRAFT_3444 1.1e-45 189.5 Verrucomicrobia trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 46SYZ@74201,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily JOKFNDED_03893 344747.PM8797T_29243 7.4e-31 139.4 Planctomycetes rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J04T@203682,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family JOKFNDED_03894 1396141.BATP01000030_gene3730 9.2e-31 139.4 Verrucomicrobiae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUNR@203494,46T6P@74201,COG0261@1,COG0261@2 NA|NA|NA J Ribosomal prokaryotic L21 protein JOKFNDED_03895 794903.OPIT5_16280 8e-66 258.5 Opitutae aas 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 Bacteria 3K7PG@414999,46SG3@74201,COG0204@1,COG0204@2,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-dependent synthetase JOKFNDED_03896 240016.ABIZ01000001_gene4753 1.3e-62 247.3 Bacteria aas GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008779,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019752,GO:0031224,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.40,2.3.1.51,6.2.1.20 ko:K00655,ko:K05939 ko00071,ko00561,ko00564,ko01100,ko01110,map00071,map00561,map00564,map01100,map01110 M00089 R01406,R02241,R04864,R09381 RC00004,RC00014,RC00037,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 iEC042_1314.EC042_3034 Bacteria COG0204@1,COG0204@2 NA|NA|NA I Acyl-transferase JOKFNDED_03897 1403819.BATR01000059_gene1838 1.1e-53 216.9 Verrucomicrobiae cicA 2.3.1.51,3.1.3.27,3.1.3.3 ko:K00655,ko:K01079,ko:K18697 ko00260,ko00561,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00561,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020,M00089 R00582,R02029,R02241,R09381 RC00004,RC00017,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004,ko01009 Bacteria 2IUJ7@203494,46XDN@74201,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase JOKFNDED_03898 1123070.KB899254_gene1185 2.9e-33 148.7 Verrucomicrobiae Bacteria 2C6YV@1,2IUKV@203494,3392Q@2,46T7D@74201 NA|NA|NA JOKFNDED_03899 497964.CfE428DRAFT_4444 1.5e-16 92.0 Verrucomicrobia Bacteria 28X6Y@1,2ZJ59@2,46WIZ@74201 NA|NA|NA JOKFNDED_03901 240016.ABIZ01000001_gene954 1.2e-45 189.1 Verrucomicrobiae Bacteria 2IVWA@203494,46VA6@74201,COG0662@1,COG0662@2 NA|NA|NA G AraC-like ligand binding domain JOKFNDED_03903 1304885.AUEY01000096_gene2839 4.7e-95 355.5 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_03904 497964.CfE428DRAFT_2503 9.5e-90 337.4 Verrucomicrobia Bacteria 46TM3@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_03905 1185876.BN8_02977 2.3e-36 159.1 Cytophagia ko:K08995 ko00000 Bacteria 47PVM@768503,4PJWM@976,COG3652@1,COG3652@2 NA|NA|NA S Domain of unknown function (DUF4142) JOKFNDED_03906 35703.DQ02_18665 2.4e-22 111.7 Gammaproteobacteria Bacteria 1NKDI@1224,1SS49@1236,2ERKU@1,33J6B@2 NA|NA|NA JOKFNDED_03907 1125863.JAFN01000001_gene2536 7.5e-54 217.2 Deltaproteobacteria gph GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1RDDY@1224,2WNN3@28221,42T69@68525,COG0546@1,COG0546@2 NA|NA|NA S HAD-superfamily hydrolase, subfamily IA, variant JOKFNDED_03908 1396141.BATP01000030_gene3694 1.1e-266 925.6 Verrucomicrobiae leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iYL1228.KPN_03016 Bacteria 2ITRE@203494,46TI3@74201,COG0119@1,COG0119@2 NA|NA|NA E HMGL-like JOKFNDED_03909 1142394.PSMK_27520 4.9e-66 258.5 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG1262@1,COG1262@2 NA|NA|NA T PFAM Formylglycine-generating sulfatase enzyme JOKFNDED_03910 1396418.BATQ01000014_gene4362 9.1e-67 260.8 Verrucomicrobiae truB 1.9.3.1,2.7.7.13,3.2.1.97,5.4.99.25 ko:K00412,ko:K00971,ko:K02275,ko:K02389,ko:K03177,ko:K17624 ko00051,ko00190,ko00520,ko01100,ko01110,ko02020,ko02040,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00051,map00190,map00520,map01100,map01110,map02020,map02040,map04260,map04714,map04932,map05010,map05012,map05016 M00114,M00151,M00152,M00155,M00361,M00362 R00081,R00885 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000,ko02035,ko03016,ko03029 3.D.4.2,3.D.4.4,3.D.4.6 GH101 Bacteria 2IU7W@203494,46YUZ@74201,COG1565@1,COG1565@2 NA|NA|NA S Putative S-adenosyl-L-methionine-dependent methyltransferase JOKFNDED_03911 1123057.P872_06740 1.8e-25 123.2 Bacteroidetes Bacteria 28J5Y@1,2Z91P@2,4NJ1D@976 NA|NA|NA S Methyltransferase domain JOKFNDED_03914 1396418.BATQ01000049_gene373 1.9e-41 175.6 Verrucomicrobiae Bacteria 2AVVV@1,2IUGY@203494,31MPP@2,46X4F@74201 NA|NA|NA JOKFNDED_03916 1206777.B195_01720 9.9e-118 431.0 Pseudomonas syringae group Bacteria 1MV2W@1224,1RQS2@1236,1Z6HK@136849,COG1835@1,COG1835@2 NA|NA|NA M Acyltransferase family JOKFNDED_03917 1396141.BATP01000004_gene5864 4.2e-145 521.2 Verrucomicrobiae Bacteria 2IW5R@203494,46XKY@74201,COG2124@1,COG2124@2 NA|NA|NA Q Cytochrome P450 JOKFNDED_03918 744980.TRICHSKD4_4311 2.4e-24 119.0 Alphaproteobacteria ko:K06975 ko00000 Bacteria 1RDJB@1224,2UB7X@28211,COG0526@1,COG0526@2,COG2388@1,COG2388@2 NA|NA|NA CO COG0526 Thiol-disulfide isomerase and thioredoxins JOKFNDED_03919 530564.Psta_2217 1e-88 333.6 Planctomycetes lolI 1.13.11.27,5.3.99.11 ko:K00457,ko:K06606 ko00130,ko00350,ko00360,ko00562,ko01100,ko01120,map00130,map00350,map00360,map00562,map01100,map01120 M00044 R01372,R02521,R09952 RC00505,RC00738,RC01513 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IY3R@203682,COG1082@1,COG1082@2 NA|NA|NA G ioli protein JOKFNDED_03920 6334.EFV55222 4.1e-26 124.8 Nematoda 1.8.1.8 ko:K17609 ko00000,ko01000,ko01009 Nematoda 3A6NN@33154,3BSGT@33208,3D9MJ@33213,40GCN@6231,KOG2501@1,KOG2501@2759 NA|NA|NA O cellular oxidant detoxification JOKFNDED_03921 1396418.BATQ01000075_gene669 3.9e-75 288.1 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IUE1@203494,46SWN@74201,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor JOKFNDED_03923 1121926.AXWO01000002_gene1626 6.4e-16 91.7 Glycomycetales ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJ96@201174,4EY90@85014,COG0265@1,COG0265@2 NA|NA|NA O PDZ domain (Also known as DHR or GLGF) JOKFNDED_03924 1123070.KB899251_gene790 9.9e-61 240.0 Verrucomicrobiae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2IU9C@203494,46SU3@74201,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO JOKFNDED_03925 1403819.BATR01000163_gene5506 1.2e-29 136.7 Verrucomicrobia Bacteria 46VIM@74201,COG2114@1,COG2114@2 NA|NA|NA T Pfam Adenylate and Guanylate cyclase catalytic domain JOKFNDED_03928 497964.CfE428DRAFT_0204 4.9e-87 328.2 Verrucomicrobia rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 46THX@74201,COG0210@1,COG0210@2 NA|NA|NA L UvrD-like helicase C-terminal domain JOKFNDED_03929 1396141.BATP01000020_gene127 1e-137 496.5 Verrucomicrobiae pilT ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2ITJW@203494,46UF2@74201,COG2805@1,COG2805@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_03930 1283300.ATXB01000001_gene1745 1.3e-28 133.3 Methylococcales mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 Bacteria 1QJKZ@1224,1THMM@1236,1XEVH@135618,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase JOKFNDED_03931 635013.TherJR_1693 3.2e-37 161.8 Peptococcaceae ytqB Bacteria 1V6VU@1239,24JEE@186801,262A2@186807,COG2519@1,COG2519@2 NA|NA|NA J rRNA Methylase JOKFNDED_03933 1121413.JMKT01000015_gene238 1.4e-38 167.5 Desulfovibrionales ko:K07003 ko00000 Bacteria 1MUE1@1224,2M919@213115,2WJRI@28221,42ME2@68525,COG1033@1,COG1033@2 NA|NA|NA K Sterol-sensing domain of SREBP cleavage-activation JOKFNDED_03934 1232410.KI421415_gene3061 2.8e-62 245.4 Deltaproteobacteria 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX8I@1224,2WNJ6@28221,42P2Z@68525,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) JOKFNDED_03935 240016.ABIZ01000001_gene5369 1.6e-24 119.8 Bacteria Bacteria COG2353@1,COG2353@2 NA|NA|NA O YceI-like domain JOKFNDED_03936 1403819.BATR01000040_gene1208 3.3e-96 358.6 Verrucomicrobiae bcsA Bacteria 2IURR@203494,46U8Y@74201,COG3424@1,COG3424@2 NA|NA|NA Q Chalcone and stilbene synthases, C-terminal domain JOKFNDED_03938 1121921.KB898707_gene834 1.9e-42 180.3 Alteromonadales genera incertae sedis czcC ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1NEZC@1224,1RPC5@1236,2PP7E@256005,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_03939 395019.Bmul_6171 8.1e-40 171.4 Burkholderiaceae czcB ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 1K187@119060,1MX8W@1224,2VJNH@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_03940 1485545.JQLW01000005_gene1092 8.2e-305 1053.1 Proteobacteria cznA ko:K07239,ko:K15726 ko00000,ko02000 2.A.6.1,2.A.6.1.2 Bacteria 1NUIV@1224,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family JOKFNDED_03941 497964.CfE428DRAFT_2104 9.6e-23 114.0 Verrucomicrobia 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 46W7N@74201,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues JOKFNDED_03942 177437.HRM2_18310 2.2e-97 363.2 Desulfobacterales Bacteria 1NMIZ@1224,2MM2H@213118,2WNF1@28221,42RXF@68525,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase JOKFNDED_03943 1122609.AUGT01000008_gene2868 7.5e-06 60.1 Bacteria 3.2.1.3 ko:K01178,ko:K14645,ko:K18546 ko00500,ko01100,ko02024,map00500,map01100,map02024 R01790,R01791,R06199 ko00000,ko00001,ko01000,ko01002,ko03110 GH15 Bacteria COG0366@1,COG0366@2,COG0515@1,COG0515@2,COG2133@1,COG2133@2,COG3227@1,COG3227@2,COG4733@1,COG4733@2 NA|NA|NA E Zinc metalloprotease (Elastase) JOKFNDED_03944 1396141.BATP01000030_gene3566 3e-08 66.2 Verrucomicrobiae Bacteria 2IV8P@203494,46UDB@74201,COG3386@1,COG3386@2,COG4733@1,COG4733@2 NA|NA|NA G Domain of unknown function (DUF5122) beta-propeller JOKFNDED_03945 240016.ABIZ01000001_gene912 3.4e-229 801.2 Verrucomicrobiae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2ITJK@203494,46SHA@74201,COG1217@1,COG1217@2 NA|NA|NA T Elongation factor G C-terminus JOKFNDED_03946 1403819.BATR01000181_gene6221 5.3e-56 224.9 Verrucomicrobia 3.1.1.85 ko:K19560 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria 46VVR@74201,COG0400@1,COG0400@2 NA|NA|NA S carboxylic ester hydrolase activity JOKFNDED_03947 497964.CfE428DRAFT_2500 2.6e-63 249.2 Verrucomicrobia tilS GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 46T0B@74201,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine JOKFNDED_03948 1403819.BATR01000049_gene1427 6.7e-38 164.1 Verrucomicrobiae maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 ko:K03215,ko:K06287 ko00000,ko01000,ko03009 Bacteria 2IUHS@203494,46VR6@74201,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein JOKFNDED_03949 1403819.BATR01000126_gene4502 2.4e-73 282.3 Verrucomicrobiae ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 2IUKN@203494,46S7X@74201,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily JOKFNDED_03950 497964.CfE428DRAFT_1007 5.8e-20 104.8 Bacteria Bacteria COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein JOKFNDED_03951 1142394.PSMK_28530 2.3e-45 189.9 Bacteria ko:K05820 ko00000,ko02000 2.A.1.27 Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily JOKFNDED_03954 1396418.BATQ01000178_gene2839 7.9e-121 440.3 Verrucomicrobiae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2ITQN@203494,46SA6@74201,COG0180@1,COG0180@2 NA|NA|NA J tRNA synthetases class I (W and Y) JOKFNDED_03955 1123072.AUDH01000021_gene2017 9.4e-70 270.4 Rhodospirillales rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 ko:K04771,ko:K11749 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU91@1224,2JPKM@204441,2TQXJ@28211,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease JOKFNDED_03956 1121106.JQKB01000002_gene3340 2.8e-126 458.4 Rhodospirillales dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 1MU4G@1224,2JQ6Y@204441,2TSD1@28211,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) JOKFNDED_03957 382464.ABSI01000013_gene1502 5.2e-68 264.6 Verrucomicrobiae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 2ITWC@203494,46SCE@74201,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family JOKFNDED_03958 497964.CfE428DRAFT_4097 1.2e-30 140.2 Verrucomicrobia ddpX 3.2.1.52,3.4.13.22 ko:K01207,ko:K08641 ko00520,ko00531,ko01100,ko01501,ko01502,ko02020,map00520,map00531,map01100,map01501,map01502,map02020 M00628,M00651 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 46VUM@74201,COG2173@1,COG2173@2 NA|NA|NA M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide JOKFNDED_03959 1396418.BATQ01000091_gene5765 2.2e-158 565.5 Verrucomicrobiae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2ITTG@203494,46S8B@74201,COG0617@1,COG0617@2 NA|NA|NA J Poly A polymerase head domain JOKFNDED_03961 1121904.ARBP01000026_gene678 5.4e-92 344.7 Cytophagia Bacteria 28JXN@1,2Z9N3@2,47NJF@768503,4NJUA@976 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella JOKFNDED_03962 240016.ABIZ01000001_gene2262 1.9e-16 92.4 Verrucomicrobiae Bacteria 2F8IJ@1,2IUYP@203494,340XC@2,46WTZ@74201 NA|NA|NA JOKFNDED_03963 240016.ABIZ01000001_gene2263 1.4e-117 429.5 Verrucomicrobiae moaA 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 Bacteria 2IU2K@203494,46V5U@74201,COG2896@1,COG2896@2 NA|NA|NA H Molybdenum Cofactor Synthesis C JOKFNDED_03964 344747.PM8797T_26410 5.6e-60 238.0 Planctomycetes ko:K09992 ko00000 Bacteria 2J0AZ@203682,COG3828@1,COG3828@2 NA|NA|NA S Methane oxygenase PmoA JOKFNDED_03966 1230343.CANP01000023_gene1491 1.6e-62 246.9 Legionellales waaM 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1JDJP@118969,1MVNI@1224,1RXSU@1236,COG1560@1,COG1560@2 NA|NA|NA M Lipid A Biosynthesis JOKFNDED_03967 1122165.AUHS01000023_gene238 1.5e-79 303.5 Legionellales 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1JD6F@118969,1MU1X@1224,1RMDE@1236,COG0304@1,COG0304@2 NA|NA|NA IQ Beta-ketoacyl synthase, C-terminal domain JOKFNDED_03968 658187.LDG_8389 1.3e-129 469.9 Legionellales 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1JDCZ@118969,1MU1X@1224,1RMDE@1236,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP JOKFNDED_03969 1034943.BN1094_02347 1.5e-24 120.2 Legionellales fabA 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1JDAD@118969,1PCKD@1224,1SXNH@1236,COG0764@1,COG0764@2 NA|NA|NA I FabA-like domain JOKFNDED_03970 497964.CfE428DRAFT_5718 4.6e-143 516.2 Verrucomicrobia Bacteria 46V2E@74201,COG3210@1,COG3210@2 NA|NA|NA U Passenger-associated-transport-repeat JOKFNDED_03972 1403819.BATR01000024_gene826 2.1e-168 600.5 Verrucomicrobiae Bacteria 2IUFG@203494,46UMW@74201,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family JOKFNDED_03973 1242864.D187_008887 7.7e-96 358.6 Deltaproteobacteria 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1MX03@1224,2WK8Q@28221,42Q71@68525,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family JOKFNDED_03975 1120934.KB894418_gene1936 1.2e-09 70.9 Pseudonocardiales Bacteria 2GKR5@201174,4DZMH@85010,COG2339@1,COG2339@2 NA|NA|NA NU Protease prsW family JOKFNDED_03976 272624.lpg0359 8.3e-35 153.3 Legionellales acpXL GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1JEJN@118969,1NM9E@1224,1SINP@1236,COG0236@1,COG0236@2 NA|NA|NA IQ Phosphopantetheine attachment site JOKFNDED_03977 344747.PM8797T_12848 7.3e-61 240.7 Planctomycetes Bacteria 2IXE0@203682,COG1028@1,COG1028@2 NA|NA|NA IQ with different specificities (related to short-chain alcohol JOKFNDED_03978 1094715.CM001373_gene2814 4.6e-72 277.7 Legionellales fabL 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1JC7V@118969,1N64Z@1224,1T3N8@1236,COG0623@1,COG0623@2 NA|NA|NA I KR domain JOKFNDED_03979 1089547.KB913013_gene3593 8.6e-17 95.5 Cytophagia ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 47QPM@768503,4NQBS@976,COG3266@1,COG3266@2 NA|NA|NA S FG-GAP repeat JOKFNDED_03980 614083.AWQR01000001_gene3031 2.4e-25 122.5 Betaproteobacteria Bacteria 1MV1P@1224,2VKJ8@28216,COG0515@1,COG0515@2,COG0745@1,COG0745@2 NA|NA|NA KLT serine threonine protein kinase JOKFNDED_03982 1396141.BATP01000030_gene3678 7e-187 660.2 Verrucomicrobiae accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITZS@203494,46SIE@74201,COG0439@1,COG0439@2 NA|NA|NA I Biotin carboxylase C-terminal domain JOKFNDED_03983 794903.OPIT5_10600 5.2e-28 131.0 Opitutae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 3K861@414999,46SXA@74201,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA JOKFNDED_03984 240016.ABIZ01000001_gene883 5.6e-108 397.9 Verrucomicrobiae Bacteria 2IW1B@203494,46SC0@74201,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V JOKFNDED_03985 1396141.BATP01000030_gene3684 1.8e-32 146.7 Verrucomicrobiae ko:K06218 ko00000,ko02048 Bacteria 2IUPU@203494,46T5H@74201,COG2026@1,COG2026@2 NA|NA|NA DJ Addiction module toxin, RelE StbE family JOKFNDED_03986 1038859.AXAU01000004_gene4599 1.5e-51 210.3 Alphaproteobacteria Bacteria 1N1DR@1224,2UV3I@28211,COG4313@1,COG4313@2 NA|NA|NA C Protein involved in meta-pathway of phenol degradation JOKFNDED_03987 1396141.BATP01000003_gene4967 6.4e-201 707.6 Verrucomicrobiae Bacteria 2IUXV@203494,46X7X@74201,COG3391@1,COG3391@2 NA|NA|NA C amine dehydrogenase activity JOKFNDED_03991 1403819.BATR01000162_gene5445 6.3e-14 83.6 Verrucomicrobiae Bacteria 2A0UE@1,2IWHT@203494,30NZ8@2,46XSZ@74201 NA|NA|NA JOKFNDED_03992 1403819.BATR01000171_gene5846 9.7e-45 186.8 Verrucomicrobiae Bacteria 2IUCI@203494,46VM3@74201,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase JOKFNDED_03993 497964.CfE428DRAFT_1580 3.6e-27 128.3 Verrucomicrobia Bacteria 2CBBS@1,33312@2,46W2R@74201 NA|NA|NA JOKFNDED_03995 1336233.JAEH01000038_gene4182 9.1e-63 246.9 Shewanellaceae Bacteria 1MU67@1224,1RR2T@1236,2QCFA@267890,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_03996 1336233.JAEH01000038_gene4181 2.6e-61 243.0 Shewanellaceae Bacteria 1QTV1@1224,1T1I6@1236,2QBJJ@267890,COG5002@1,COG5002@2 NA|NA|NA T Member of a two-component regulatory system JOKFNDED_03998 1396418.BATQ01000007_gene1406 1.4e-58 232.6 Verrucomicrobiae Bacteria 2IUDX@203494,46W96@74201,COG1510@1,COG1510@2 NA|NA|NA K regulation of RNA biosynthetic process JOKFNDED_03999 1242864.D187_004703 8.2e-81 307.4 Deltaproteobacteria yfcH ko:K07071 ko00000 Bacteria 1MUB4@1224,2WKRY@28221,42QUU@68525,COG1090@1,COG1090@2 NA|NA|NA S epimerase dehydratase JOKFNDED_04000 1403819.BATR01000029_gene948 3.5e-42 178.7 Bacteria Bacteria COG3361@1,COG3361@2 NA|NA|NA S conserved protein (COG2071) JOKFNDED_04001 1142394.PSMK_13280 2.8e-45 188.7 Planctomycetes Bacteria 2IYGB@203682,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_04002 1341646.CBMO010000146_gene4886 1.1e-65 256.9 Mycobacteriaceae Bacteria 2335D@1762,2GM0X@201174,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase JOKFNDED_04003 247634.GPB2148_2746 1.3e-41 176.8 Proteobacteria Bacteria 1RIRU@1224,COG1028@1,COG1028@2 NA|NA|NA IQ NAD dependent epimerase/dehydratase family JOKFNDED_04004 1142394.PSMK_13270 2.5e-135 488.8 Planctomycetes ko:K00479 ko00000 Bacteria 2J0EZ@203682,COG4638@1,COG4638@2 NA|NA|NA P Ring hydroxylating alpha subunit (catalytic domain) JOKFNDED_04005 398527.Bphyt_5232 1.1e-78 300.1 Burkholderiaceae Bacteria 1K1K9@119060,1Q3WR@1224,2W8A3@28216,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase JOKFNDED_04006 1142394.PSMK_13280 1.4e-46 193.0 Planctomycetes Bacteria 2IYGB@203682,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_04007 1479237.JMLY01000001_gene3280 4.3e-116 424.9 Alteromonadaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MVJA@1224,1RRP5@1236,469H5@72275,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family JOKFNDED_04008 999611.KI421504_gene1515 3.4e-75 288.5 Alphaproteobacteria ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MWDJ@1224,2TRDG@28211,COG0600@1,COG0600@2 NA|NA|NA P ABC-type nitrate sulfonate bicarbonate transport system permease component JOKFNDED_04009 661478.OP10G_2769 2.6e-24 118.6 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity JOKFNDED_04010 1396141.BATP01000056_gene3293 1e-81 310.8 Verrucomicrobiae Bacteria 2IV49@203494,46UST@74201,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_04011 1403819.BATR01000114_gene3941 7.5e-78 297.0 Verrucomicrobiae Bacteria 2IV1F@203494,46V7A@74201,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_04014 1454004.AW11_02462 2.1e-94 353.2 unclassified Betaproteobacteria yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1KR09@119066,1MW5T@1224,2VI22@28216,COG0025@1,COG0025@2 NA|NA|NA PT CPA1 family monovalent cation H antiporter JOKFNDED_04015 240016.ABIZ01000001_gene731 5.1e-87 327.8 Verrucomicrobiae folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS03115 Bacteria 2IV7G@203494,46UK2@74201,COG0294@1,COG0294@2 NA|NA|NA H Pterin binding enzyme JOKFNDED_04017 1396141.BATP01000024_gene763 8.9e-49 202.6 Verrucomicrobiae Bacteria 29Z68@1,2IVX2@203494,30M44@2,46XH9@74201 NA|NA|NA JOKFNDED_04021 1403819.BATR01000059_gene1822 8.3e-55 219.5 Bacteria 5.3.3.19 ko:K19547 ko01130,map01130 M00787 ko00000,ko00001,ko00002,ko01000 Bacteria COG0662@1,COG0662@2 NA|NA|NA G Cupin 2, conserved barrel domain protein JOKFNDED_04022 1396418.BATQ01000009_gene3838 2.5e-77 295.4 Verrucomicrobiae phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 2IU7C@203494,46SRW@74201,COG1235@1,COG1235@2 NA|NA|NA S Metallo-beta-lactamase superfamily JOKFNDED_04023 1396141.BATP01000019_gene1607 2.3e-152 545.8 Verrucomicrobiae recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03631 ko00000,ko03400 Bacteria 2IU0W@203494,46SGB@74201,COG0497@1,COG0497@2 NA|NA|NA L RecF/RecN/SMC N terminal domain JOKFNDED_04024 1123508.JH636449_gene7271 2e-53 215.7 Planctomycetes Bacteria 2E71G@1,2J2DH@203682,331K5@2 NA|NA|NA S Uncharacterised nucleotidyltransferase JOKFNDED_04025 1123070.KB899255_gene1382 1.1e-162 580.1 Verrucomicrobiae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2ITRD@203494,46SNV@74201,COG0608@1,COG0608@2 NA|NA|NA L DHHA1 domain JOKFNDED_04026 1210884.HG799463_gene9414 1.5e-58 233.0 Planctomycetes Bacteria 2IZ2H@203682,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase JOKFNDED_04027 1396418.BATQ01000008_gene1475 6.8e-251 873.2 Verrucomicrobiae ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 Bacteria 2IU3F@203494,46SEF@74201,COG0821@1,COG0821@2 NA|NA|NA I GcpE protein JOKFNDED_04028 1396418.BATQ01000008_gene1474 2.6e-123 449.1 Verrucomicrobiae rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 2ITH1@203494,46S9B@74201,COG0750@1,COG0750@2 NA|NA|NA M Peptidase family M50 JOKFNDED_04029 497964.CfE428DRAFT_0150 7.1e-48 196.8 Verrucomicrobia dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 46STH@74201,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality JOKFNDED_04031 1396418.BATQ01000168_gene1825 5.4e-78 297.0 Verrucomicrobiae sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 ko:K07033,ko:K09014 ko00000 iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 Bacteria 2IU30@203494,46SGN@74201,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) JOKFNDED_04032 1123070.KB899261_gene2127 7.2e-104 384.4 Verrucomicrobiae sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K07033,ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2ITRN@203494,46S8S@74201,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) JOKFNDED_04033 1235788.C802_01512 1e-16 93.2 Bacteroidaceae Bacteria 2FTP8@200643,4ARVS@815,4NSS3@976,COG1569@1,COG1569@2 NA|NA|NA S Toxin-antitoxin system, toxin component, PIN family JOKFNDED_04035 1396141.BATP01000025_gene909 5.9e-34 150.2 Verrucomicrobiae Bacteria 2IUGC@203494,46VKC@74201,COG2947@1,COG2947@2 NA|NA|NA S EVE domain JOKFNDED_04036 1396141.BATP01000039_gene1275 2.2e-70 273.1 Verrucomicrobiae Bacteria 2IVKV@203494,46S9G@74201,COG2202@1,COG2202@2,COG5000@1,COG5000@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain JOKFNDED_04038 1396141.BATP01000030_gene3541 1.5e-247 862.8 Verrucomicrobiae 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2IVA5@203494,46TMA@74201,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG4942@1,COG4942@2 NA|NA|NA CG Cytochrome c JOKFNDED_04039 344747.PM8797T_07452 7.6e-145 520.8 Planctomycetes Bacteria 2J537@203682,COG2133@1,COG2133@2 NA|NA|NA G Trehalose utilisation JOKFNDED_04040 1396141.BATP01000030_gene3785 1.9e-14 85.1 Verrucomicrobiae Bacteria 2E63P@1,2IWAQ@203494,32K49@2,46WKT@74201 NA|NA|NA JOKFNDED_04041 497964.CfE428DRAFT_0312 5.9e-230 803.5 Verrucomicrobia Bacteria 46TYV@74201,COG0657@1,COG0657@2,COG1413@1,COG1413@2 NA|NA|NA CI Carboxylesterase family JOKFNDED_04042 1230476.C207_06361 1.3e-22 113.2 Bradyrhizobiaceae MA20_01935 Bacteria 1MZ9T@1224,2UC4H@28211,3JV3F@41294,COG3319@1,COG3319@2 NA|NA|NA Q amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_04044 526225.Gobs_5053 2.5e-16 92.4 Actinobacteria Bacteria 2IIDW@201174,COG2020@1,COG2020@2 NA|NA|NA O Phospholipid methyltransferase JOKFNDED_04046 1123401.JHYQ01000043_gene762 2.2e-16 91.3 Bacteria Bacteria COG2161@1,COG2161@2 NA|NA|NA D toxin-antitoxin pair type II binding JOKFNDED_04047 1348657.M622_16015 1.4e-21 109.4 Betaproteobacteria vapC ko:K07062 ko00000,ko01000,ko02048 Bacteria 1RIB5@1224,2VSZV@28216,COG1487@1,COG1487@2 NA|NA|NA E Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_04048 1403819.BATR01000164_gene5622 2.9e-187 661.4 Verrucomicrobiae ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2ITNZ@203494,46SB7@74201,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins JOKFNDED_04049 530564.Psta_1775 7.8e-183 647.5 Planctomycetes 1.11.1.15 ko:K03386,ko:K03564,ko:K16922 ko04214,map04214 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 2IXTF@203682,COG0457@1,COG0457@2,COG1225@1,COG1225@2 NA|NA|NA O Tetratricopeptide repeat JOKFNDED_04050 344747.PM8797T_17127 2.8e-89 335.1 Planctomycetes Bacteria 2IYWU@203682,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) JOKFNDED_04051 756272.Plabr_4375 7.9e-60 237.3 Planctomycetes galA Bacteria 2J2DV@203682,COG3420@1,COG3420@2 NA|NA|NA P Right handed beta helix region JOKFNDED_04052 794903.OPIT5_26355 1.6e-147 529.3 Opitutae adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 3K7G4@414999,46UF6@74201,COG0563@1,COG0563@2 NA|NA|NA F adenylate kinase JOKFNDED_04054 240016.ABIZ01000001_gene5361 5.8e-169 600.5 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_04055 240016.ABIZ01000001_gene5360 2.5e-205 722.6 Verrucomicrobiae Bacteria 2IV3X@203494,46TGZ@74201,COG0642@1,COG0642@2,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_04057 794903.OPIT5_15125 4.1e-58 231.5 Opitutae Bacteria 3K7WH@414999,46VWY@74201,COG0745@1,COG0745@2 NA|NA|NA K Two component transcriptional regulator, winged helix family JOKFNDED_04058 497964.CfE428DRAFT_5953 3.1e-76 293.1 Verrucomicrobia Bacteria 46Z6V@74201,COG0642@1,COG2205@2 NA|NA|NA T PFAM ATP-binding region ATPase domain protein JOKFNDED_04061 583355.Caka_2747 6.1e-105 387.5 Opitutae troA GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K11707 ko02010,map02010 M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15 Bacteria 3K9N3@414999,46ZE6@74201,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family JOKFNDED_04062 382464.ABSI01000013_gene1595 5.1e-47 194.5 Verrucomicrobia sirR ko:K03709 ko00000,ko03000 Bacteria 46T7C@74201,COG1321@1,COG1321@2 NA|NA|NA K FeoA JOKFNDED_04063 880071.Fleli_2865 8.5e-26 123.6 Cytophagia Bacteria 299NP@1,2ZWR1@2,47R54@768503,4NP8Q@976 NA|NA|NA JOKFNDED_04064 497964.CfE428DRAFT_1108 1.7e-111 409.1 Bacteria 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria COG0388@1,COG0388@2 NA|NA|NA S hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds JOKFNDED_04065 1396141.BATP01000022_gene449 8.5e-195 688.3 Verrucomicrobiae psrP1 ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IVDX@203494,46TW3@74201,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3468@1,COG3468@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase JOKFNDED_04066 1123242.JH636434_gene4040 1.9e-101 375.6 Planctomycetes Bacteria 2IXY7@203682,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_04068 1396141.BATP01000030_gene3611 1.5e-56 225.7 Verrucomicrobiae rsuA 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2IUHB@203494,46V36@74201,COG1187@1,COG1187@2 NA|NA|NA J RNA pseudouridylate synthase JOKFNDED_04069 1396418.BATQ01000016_gene4234 2.2e-111 408.7 Verrucomicrobiae 3.2.1.8 ko:K01181 ko00000,ko01000 Bacteria 2IV28@203494,46U2T@74201,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold JOKFNDED_04071 344747.PM8797T_02919 4.9e-244 850.9 Planctomycetes Bacteria 2IXTE@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04072 1396141.BATP01000039_gene1322 2.5e-22 112.5 Verrucomicrobiae yfiQ ko:K09181 ko00000 iAF987.Gmet_2142 Bacteria 2IW7W@203494,46XMY@74201,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase JOKFNDED_04073 1396141.BATP01000002_gene4844 1e-127 463.4 Verrucomicrobiae ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2ITXS@203494,46S7U@74201,COG0686@1,COG0686@2 NA|NA|NA E Alanine dehydrogenase/PNT, N-terminal domain JOKFNDED_04074 1403819.BATR01000005_gene160 1.6e-36 160.6 Verrucomicrobia Bacteria 2A84C@1,30X53@2,46SPC@74201 NA|NA|NA JOKFNDED_04075 240016.ABIZ01000001_gene4590 2.3e-53 216.5 Verrucomicrobia Bacteria 2A84C@1,30X53@2,46SPC@74201 NA|NA|NA JOKFNDED_04077 1120968.AUBX01000009_gene345 1e-55 223.8 Cytophagia msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 47PB4@768503,4NMAJ@976,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine JOKFNDED_04080 497964.CfE428DRAFT_2483 2.7e-46 192.6 Verrucomicrobia ko:K03298 ko00000,ko02000 2.A.7.3 Bacteria 46SR7@74201,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family JOKFNDED_04081 443255.SCLAV_0774 9.9e-48 197.2 Actinobacteria 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase JOKFNDED_04082 1396141.BATP01000004_gene5819 1.4e-142 513.1 Verrucomicrobiae ko:K09806 ko00000 Bacteria 2IVAW@203494,46UCE@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_04084 1396141.BATP01000047_gene3998 8.5e-27 128.3 Verrucomicrobia Bacteria 29243@1,2ZPP3@2,46WH9@74201 NA|NA|NA JOKFNDED_04086 1403819.BATR01000164_gene5609 5.8e-57 228.0 Verrucomicrobiae Bacteria 2ITMK@203494,46UQU@74201,COG1649@1,COG1649@2 NA|NA|NA S Glycosyl hydrolase-like 10 JOKFNDED_04088 1396141.BATP01000001_gene5302 1.4e-32 146.7 Verrucomicrobiae lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_2567 Bacteria 2IU6J@203494,46SQN@74201,COG1043@1,COG1043@2 NA|NA|NA M Udp N-acetylglucosamine O-acyltransferase; Domain 2 JOKFNDED_04089 1396418.BATQ01000171_gene2957 1.1e-92 347.4 Verrucomicrobiae Bacteria 2IU6N@203494,46YW4@74201,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_04091 870187.Thini_4269 1.2e-13 82.0 Gammaproteobacteria Bacteria 1NMKJ@1224,1SIPI@1236,2EG83@1,339ZW@2 NA|NA|NA JOKFNDED_04092 324925.Ppha_0757 1.1e-34 152.9 Bacteria Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_04093 1396418.BATQ01000047_gene6221 1.4e-126 459.9 Verrucomicrobiae Bacteria 2ITZ3@203494,46TM9@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_04094 1123508.JH636443_gene4557 4e-62 245.7 Planctomycetes Bacteria 2IX4E@203682,COG5434@1,COG5434@2 NA|NA|NA M Periplasmic copper-binding protein (NosD) JOKFNDED_04095 595460.RRSWK_03607 6.3e-141 507.3 Planctomycetes Bacteria 2IXG7@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_04096 1396418.BATQ01000001_gene1251 1.8e-188 665.6 Verrucomicrobiae Bacteria 2IUAW@203494,46SHT@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_04097 1123242.JH636435_gene2296 4.5e-165 587.8 Planctomycetes 3.1.6.6 ko:K01133 ko00000,ko01000 Bacteria 2IXUN@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_04098 1123242.JH636435_gene2295 2.7e-159 568.5 Planctomycetes Bacteria 2J1XV@203682,COG3119@1,COG3119@2 NA|NA|NA P Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_04101 313628.LNTAR_17138 2.5e-147 528.9 Bacteria Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_04102 595460.RRSWK_02626 5.7e-147 527.7 Bacteria Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_04103 240016.ABIZ01000001_gene617 1e-80 307.8 Verrucomicrobia Bacteria 2DZRA@1,32VGT@2,46TAC@74201 NA|NA|NA JOKFNDED_04105 1121918.ARWE01000001_gene2853 2.1e-22 113.6 Proteobacteria Bacteria 1RIRN@1224,2C1C3@1,32R8E@2 NA|NA|NA JOKFNDED_04106 344747.PM8797T_26840 3.4e-154 551.6 Planctomycetes Bacteria 2IXDR@203682,COG0673@1,COG0673@2 NA|NA|NA S dehydrogenases and related proteins JOKFNDED_04107 344747.PM8797T_05495 5.3e-19 102.1 Bacteria ko:K18353 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01504 Bacteria COG3021@1,COG3021@2 NA|NA|NA S interspecies interaction between organisms JOKFNDED_04108 1396418.BATQ01000106_gene5347 1.5e-89 335.9 Verrucomicrobiae araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0019752,GO:0019852,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0051186,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_4403,iHN637.CLJU_RS00590,iLF82_1304.LF82_2127,iNRG857_1313.NRG857_17845,iSDY_1059.SDY_4367,iSSON_1240.SSON_0067 Bacteria 2IUBM@203494,46U10@74201,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain JOKFNDED_04110 1403819.BATR01000129_gene4563 1.6e-159 569.3 Verrucomicrobiae Bacteria 2ITHB@203494,46UZ5@74201,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_04111 382464.ABSI01000011_gene2675 3.4e-99 369.0 Verrucomicrobiae ko:K03299 ko00000,ko02000 2.A.8 Bacteria 2IVYC@203494,46UQS@74201,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease JOKFNDED_04112 240016.ABIZ01000001_gene253 7.5e-171 607.1 Verrucomicrobiae ko:K03307 ko00000 2.A.21 Bacteria 2IVV1@203494,46UFJ@74201,COG0591@1,COG0591@2 NA|NA|NA E Sodium:solute symporter family JOKFNDED_04113 1396418.BATQ01000133_gene4097 2.1e-145 522.3 Verrucomicrobiae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 2IVFG@203494,46U9R@74201,COG3158@1,COG3158@2 NA|NA|NA P K+ potassium transporter JOKFNDED_04114 497964.CfE428DRAFT_0348 5.2e-196 691.4 Verrucomicrobia pqqL ko:K07263 ko00000,ko01000,ko01002 Bacteria 46S9I@74201,COG0612@1,COG0612@2 NA|NA|NA S PFAM peptidase M16 domain protein JOKFNDED_04115 452637.Oter_2367 1.8e-25 122.5 Opitutae Bacteria 2E5IJ@1,3309Y@2,3K87A@414999,46SYV@74201 NA|NA|NA JOKFNDED_04116 452637.Oter_4402 4.1e-14 84.7 Verrucomicrobia Bacteria 46WX9@74201,COG3678@1,COG3678@2 NA|NA|NA NPTU Heavy-metal resistance JOKFNDED_04117 1096930.L284_00435 2.9e-31 142.1 Sphingomonadales ko:K03088 ko00000,ko03021 Bacteria 1MX7T@1224,2KAEY@204457,2U182@28211,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_04118 1396141.BATP01000046_gene1882 4.9e-203 714.5 Verrucomicrobiae ko:K02014 ko00000,ko02000 1.B.14 Bacteria 2ITHD@203494,46ZHZ@74201,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug Domain JOKFNDED_04119 1396418.BATQ01000144_gene3442 3.1e-57 228.0 Verrucomicrobiae Bacteria 2IWFC@203494,46XRK@74201,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein JOKFNDED_04121 240016.ABIZ01000001_gene4419 1.4e-66 259.2 Verrucomicrobiae hom 1.1.1.3,2.2.1.6 ko:K00003,ko:K01653 ko00260,ko00270,ko00290,ko00300,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00270,map00290,map00300,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00017,M00018,M00019,M00570 R00006,R00014,R00226,R01773,R01775,R03050,R04672,R04673,R08648 RC00027,RC00087,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU7V@203494,46SUP@74201,COG0440@1,COG0440@2 NA|NA|NA E ACT domain JOKFNDED_04122 1396418.BATQ01000049_gene420 3.6e-265 920.6 Verrucomicrobiae ilvB 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iYO844.BSU28310 Bacteria 2ITSM@203494,46S72@74201,COG0028@1,COG0028@2 NA|NA|NA EH Thiamine pyrophosphate enzyme, central domain JOKFNDED_04123 1245469.S58_43940 3.6e-41 174.9 Bradyrhizobiaceae ko:K07112 ko00000 Bacteria 1RIWE@1224,2U4F1@28211,3JWRH@41294,COG2391@1,COG2391@2 NA|NA|NA S Sulphur transport JOKFNDED_04124 1245469.S58_43950 6.9e-47 193.7 Bradyrhizobiaceae ko:K07112 ko00000 Bacteria 1R5DN@1224,2U2XY@28211,3JVBJ@41294,COG2391@1,COG2391@2 NA|NA|NA S Sulphur transport JOKFNDED_04125 1185876.BN8_02686 5.7e-15 87.4 Cytophagia glpE Bacteria 47RW1@768503,4NUPH@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain JOKFNDED_04126 452637.Oter_1454 0.0 1319.3 Verrucomicrobia Bacteria 46SER@74201,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family JOKFNDED_04127 382464.ABSI01000006_gene841 1.6e-47 196.8 Verrucomicrobia Bacteria 46US2@74201,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like JOKFNDED_04128 697281.Mahau_2042 1.1e-11 77.0 Firmicutes Bacteria 1V10C@1239,COG1388@1,COG1388@2 NA|NA|NA M PFAM LysM domain JOKFNDED_04130 335543.Sfum_0219 3.2e-218 765.4 Syntrophobacterales bcsC 1.8.1.9,2.7.11.1 ko:K00384,ko:K02453,ko:K11912,ko:K14949,ko:K20543 ko00450,ko02025,ko03070,ko05111,ko05152,map00450,map02025,map03070,map05111,map05152 M00331 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02044 1.B.55.3,3.A.15 Bacteria 1NBJ6@1224,2MRX9@213462,2WSZG@28221,42XTF@68525,COG0457@1,COG0457@2,COG3118@1,COG3118@2,COG3379@1,COG3379@2 NA|NA|NA O Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_04131 1396141.BATP01000033_gene4251 3.7e-26 124.4 Verrucomicrobiae rbpD Bacteria 2IUHZ@203494,46VMU@74201,COG0724@1,COG0724@2 NA|NA|NA S RNA recognition motif JOKFNDED_04132 1123070.KB899247_gene1537 9.8e-63 248.4 Verrucomicrobiae Bacteria 2ITZK@203494,46TX9@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase JOKFNDED_04133 1480694.DC28_15000 5.6e-76 291.2 Bacteria scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria COG1940@1,COG1940@2 NA|NA|NA GK ROK family JOKFNDED_04134 1396418.BATQ01000149_gene2218 2.5e-36 159.1 Verrucomicrobiae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2IUXU@203494,46W0A@74201,COG0569@1,COG0569@2 NA|NA|NA P TrkA-N domain JOKFNDED_04135 349741.Amuc_0806 3.9e-89 335.9 Verrucomicrobiae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2IVH0@203494,46U92@74201,COG0168@1,COG0168@2 NA|NA|NA P Cation transport protein JOKFNDED_04137 1120965.AUBV01000004_gene737 1.3e-119 436.4 Cytophagia 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 47JHU@768503,4NDYZ@976,COG2355@1,COG2355@2 NA|NA|NA E PFAM Peptidase M19, renal dipeptidase JOKFNDED_04138 314278.NB231_06401 7.4e-47 193.4 Gammaproteobacteria GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 ko:K07064 ko00000 Bacteria 1N8VX@1224,1SP0Z@1236,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_04139 266940.Krad_1614 4.7e-20 105.1 Actinobacteria spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ12@201174,COG0566@1,COG0566@2 NA|NA|NA J rRNA methyltransferase JOKFNDED_04141 1396141.BATP01000006_gene5499 6.7e-128 463.8 Verrucomicrobiae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU0V@203494,46SE1@74201,COG0825@1,COG0825@2 NA|NA|NA I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit JOKFNDED_04142 1396418.BATQ01000113_gene4633 1.3e-42 180.3 Verrucomicrobiae Bacteria 2IURM@203494,46W0P@74201,COG1376@1,COG1376@2 NA|NA|NA S Lysin motif JOKFNDED_04143 1403819.BATR01000118_gene4083 1.5e-44 186.0 Verrucomicrobiae Bacteria 2CNXM@1,2IUHE@203494,32SI1@2,46SZC@74201 NA|NA|NA JOKFNDED_04144 497964.CfE428DRAFT_1901 3.2e-23 114.0 Verrucomicrobia acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 46T18@74201,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis JOKFNDED_04145 240016.ABIZ01000001_gene4652 2.5e-153 548.5 Verrucomicrobiae thiH GO:0003674,GO:0003824,GO:0005488,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0036355,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.19 ko:K03150 ko00730,ko01100,map00730,map01100 R10246 RC01434,RC03095 ko00000,ko00001,ko01000 iPC815.YPO3743,iSF_1195.SF4062,iSFxv_1172.SFxv_4429,iS_1188.S3673 Bacteria 2ITUU@203494,46SFX@74201,COG0502@1,COG0502@2 NA|NA|NA H Biotin and Thiamin Synthesis associated domain JOKFNDED_04146 1121085.AUCI01000009_gene2966 1e-09 68.9 Bacteria thiS ko:K03154 ko04122,map04122 ko00000,ko00001 iJN678.ycf40 Bacteria COG2104@1,COG2104@2 NA|NA|NA H thiamine diphosphate biosynthetic process JOKFNDED_04148 521674.Plim_2153 2.7e-135 488.4 Planctomycetes fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z4263 Bacteria 2IYZ9@203682,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II JOKFNDED_04149 153721.MYP_1286 1.3e-63 250.4 Cytophagia Bacteria 47KQ0@768503,4NIR9@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family JOKFNDED_04150 1121022.ABENE_21205 5.1e-76 291.2 Proteobacteria 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 1R6DX@1224,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) JOKFNDED_04151 583355.Caka_3043 6.3e-26 124.0 Bacteria Bacteria 2E5NI@1,330DB@2 NA|NA|NA JOKFNDED_04153 909663.KI867150_gene1636 7.3e-131 473.8 Syntrophobacterales degT 2.6.1.98 ko:K13017 ko00520,map00520 R10141 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1MUPN@1224,2MR0E@213462,2WJ1Q@28221,42M4C@68525,COG0399@1,COG0399@2 NA|NA|NA E Beta-eliminating lyase JOKFNDED_04154 1396141.BATP01000023_gene586 4.7e-19 99.8 Verrucomicrobiae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUR8@203494,46WMF@74201,COG0230@1,COG0230@2 NA|NA|NA J Ribosomal protein L34 JOKFNDED_04155 497964.CfE428DRAFT_1421 4.7e-10 70.5 Verrucomicrobia rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 46WEU@74201,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme JOKFNDED_04156 1403819.BATR01000092_gene2742 5.2e-19 100.5 Verrucomicrobiae yidD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217,ko:K08998 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2IW7G@203494,46W3D@74201,COG0759@1,COG0759@2 NA|NA|NA S Haemolytic JOKFNDED_04157 1396141.BATP01000023_gene588 4.6e-96 359.0 Verrucomicrobiae yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2ITX0@203494,46SHI@74201,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins JOKFNDED_04160 1403819.BATR01000181_gene6124 1.5e-60 240.0 Verrucomicrobiae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 2IUN9@203494,46V70@74201,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein JOKFNDED_04161 497964.CfE428DRAFT_4665 4.5e-26 124.4 Verrucomicrobia nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 46T7V@74201,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons JOKFNDED_04162 1396418.BATQ01000098_gene6002 3.8e-87 328.2 Verrucomicrobiae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2ITIZ@203494,46SKC@74201,COG0552@1,COG0552@2 NA|NA|NA U SRP54-type protein, GTPase domain JOKFNDED_04163 1267533.KB906736_gene1260 1.3e-19 104.0 Bacteria Bacteria COG2340@1,COG2340@2 NA|NA|NA S peptidase inhibitor activity JOKFNDED_04164 1396141.BATP01000056_gene3287 1.9e-62 245.7 Verrucomicrobiae rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 ko:K06178,ko:K06181 ko00000,ko01000,ko03009 Bacteria 2IU9S@203494,46V8C@74201,COG1187@1,COG1187@2 NA|NA|NA J RNA pseudouridylate synthase JOKFNDED_04165 1123400.KB904791_gene136 1.1e-35 156.0 Gammaproteobacteria panD 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1RI1B@1224,1S66E@1236,COG0853@1,COG0853@2 NA|NA|NA H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine JOKFNDED_04166 1173028.ANKO01000164_gene2743 3.3e-15 89.4 Oscillatoriales yfbL Bacteria 1G1QW@1117,1H7N7@1150,COG2234@1,COG2234@2 NA|NA|NA S PFAM Peptidase family M28 JOKFNDED_04167 1396141.BATP01000056_gene3186 7e-86 324.3 Verrucomicrobiae lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478,iIT341.HP0867 Bacteria 2ITSK@203494,46SSG@74201,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell JOKFNDED_04168 357808.RoseRS_1787 4.2e-17 93.6 Bacteria Bacteria COG1598@1,COG1598@2 NA|NA|NA N PFAM Uncharacterised protein family UPF0150 JOKFNDED_04169 118173.KB235914_gene759 4.5e-24 118.2 Oscillatoriales Bacteria 1G3WZ@1117,1HDM6@1150,2BWJ3@1,2Z7IQ@2 NA|NA|NA S Sulfotransferase domain JOKFNDED_04170 1313301.AUGC01000004_gene2420 6.1e-52 210.7 Bacteroidetes phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 4NDWB@976,COG1235@1,COG1235@2 NA|NA|NA S of the beta-lactamase superfamily I JOKFNDED_04172 1403819.BATR01000033_gene1108 4.4e-56 224.2 Verrucomicrobia ko:K07004 ko00000 Bacteria 46TT4@74201,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase JOKFNDED_04173 1347368.HG964408_gene7020 6.7e-90 337.0 Bacillus Bacteria 1TSVH@1239,1ZCFB@1386,4HD5V@91061,COG2013@1,COG2013@2 NA|NA|NA S Mitochondrial biogenesis AIM24 JOKFNDED_04174 497964.CfE428DRAFT_2116 6.8e-11 73.9 Verrucomicrobia Bacteria 2DTM2@1,33KVG@2,46T9U@74201 NA|NA|NA JOKFNDED_04175 240016.ABIZ01000001_gene2381 4.7e-120 438.7 Verrucomicrobiae Bacteria 2BZ41@1,2ITI9@203494,2ZDAE@2,46SM4@74201 NA|NA|NA JOKFNDED_04176 497964.CfE428DRAFT_2171 1.7e-26 127.1 Verrucomicrobia Bacteria 46VEG@74201,COG1376@1,COG1376@2 NA|NA|NA S PFAM ErfK YbiS YcfS YnhG family protein JOKFNDED_04177 497964.CfE428DRAFT_0982 1.1e-85 323.2 Verrucomicrobia Bacteria 46TQ0@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1553) JOKFNDED_04178 497964.CfE428DRAFT_0983 1e-220 772.7 Verrucomicrobia Bacteria 46TI1@74201,COG1524@1,COG1524@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04179 1123070.KB899248_gene63 7e-41 174.9 Verrucomicrobiae Bacteria 2IW4X@203494,46XKI@74201,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) JOKFNDED_04180 382464.ABSI01000005_gene1378 2.4e-44 186.8 Verrucomicrobiae Bacteria 2IVF7@203494,46WEI@74201,COG1262@1,COG1262@2 NA|NA|NA N Sulfatase-modifying factor enzyme 1 JOKFNDED_04182 1267535.KB906767_gene1686 2.6e-101 375.9 Bacteria Bacteria COG3356@1,COG3356@2 NA|NA|NA JOKFNDED_04183 240016.ABIZ01000001_gene5718 1.2e-162 579.7 Verrucomicrobia Bacteria 46TNY@74201,COG1524@1,COG1524@2 NA|NA|NA U Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_04185 419947.MRA_2557 4.8e-11 74.3 Mycobacteriaceae GO:0005575,GO:0005576,GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 ko:K07064 ko00000 Bacteria 23DKE@1762,2GVWT@201174,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_04186 269799.Gmet_1232 4.9e-80 305.4 Desulfuromonadales gntK GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 2.7.1.12 ko:K00851,ko:K07028 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 R01737 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MU9M@1224,2WJ5R@28221,42NEZ@68525,43U4X@69541,COG0645@1,COG0645@2,COG2187@1,COG2187@2 NA|NA|NA S AAA domain JOKFNDED_04187 1415755.JQLV01000001_gene2903 3.1e-186 658.3 Oceanospirillales yidK GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015291,GO:0015293,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K03307 ko00000 2.A.21 iECIAI1_1343.ECIAI1_3857,iECO111_1330.ECO111_4504,iECO26_1355.ECO26_4903,iECSE_1348.ECSE_3965,iECW_1372.ECW_m3979,iEKO11_1354.EKO11_0023,iEcE24377_1341.EcE24377A_4187,iWFL_1372.ECW_m3979 Bacteria 1MXWV@1224,1RR4S@1236,1XNYN@135619,COG4146@1,COG4146@2 NA|NA|NA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family JOKFNDED_04188 1396141.BATP01000007_gene5686 5e-128 464.5 Verrucomicrobiae mro 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU12@203494,46TS8@74201,COG2017@1,COG2017@2 NA|NA|NA G Converts alpha-aldose to the beta-anomer JOKFNDED_04189 521674.Plim_4107 1.8e-83 316.2 Planctomycetes Bacteria 2BHSQ@1,2IZJZ@203682,32BWA@2 NA|NA|NA S Methane oxygenase PmoA JOKFNDED_04190 1396418.BATQ01000003_gene1350 7.3e-244 850.5 Verrucomicrobiae lig GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K07577,ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2ITPW@203494,46SCR@74201,COG1236@1,COG1236@2,COG1793@1,COG1793@2 NA|NA|NA JL DNA ligase N terminus JOKFNDED_04191 1288963.ADIS_3142 1.3e-170 606.7 Cytophagia ko:K01138 ko00000,ko01000 Bacteria 47NF5@768503,4NEZJ@976,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_04192 667632.KB890217_gene4863 1.1e-195 689.5 Burkholderiaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1K0BX@119060,1MUP7@1224,2VICH@28216,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate JOKFNDED_04193 1121930.AQXG01000010_gene3079 1.8e-22 113.2 Bacteria Bacteria COG2430@1,COG2430@2 NA|NA|NA JOKFNDED_04194 96561.Dole_2998 6e-27 129.0 Deltaproteobacteria Bacteria 1Q6SW@1224,28M10@1,2WYEK@28221,32F9I@2,433RC@68525 NA|NA|NA S Domain of unknown function (DUF4403) JOKFNDED_04195 1396418.BATQ01000025_gene5255 2.9e-201 708.8 Verrucomicrobia Bacteria 46TMQ@74201,COG1073@1,COG1073@2 NA|NA|NA S alpha beta JOKFNDED_04196 240016.ABIZ01000001_gene5840 5.8e-09 66.6 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_04197 907348.TresaDRAFT_2467 9e-19 99.8 Spirochaetes yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2J8D6@203691,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase, YajC subunit JOKFNDED_04198 1403819.BATR01000033_gene1098 5.8e-169 601.7 Verrucomicrobiae secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2ITYV@203494,46SA4@74201,COG0341@1,COG0341@2,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA JOKFNDED_04199 1396141.BATP01000027_gene1129 8.2e-63 248.1 Bacteria Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity JOKFNDED_04200 1519464.HY22_11920 3.1e-65 256.1 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_04201 1396418.BATQ01000142_gene3288 2.9e-217 761.9 Verrucomicrobiae pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2ITHP@203494,46SDG@74201,COG0072@1,COG0072@2 NA|NA|NA J B3/4 domain JOKFNDED_04202 1123070.KB899257_gene2286 3.3e-133 481.5 Verrucomicrobiae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2ITTX@203494,46S6R@74201,COG0016@1,COG0016@2 NA|NA|NA J Aminoacyl tRNA synthetase class II, N-terminal domain JOKFNDED_04203 1396141.BATP01000022_gene360 2e-35 155.2 Verrucomicrobiae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUFE@203494,46SZW@74201,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit JOKFNDED_04204 1454007.JAUG01000059_gene3539 4.9e-24 117.5 Sphingobacteriia Bacteria 1IS8Q@117747,4NECA@976,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family JOKFNDED_04206 857293.CAAU_0360 2.3e-19 102.1 Clostridiaceae ywlE 3.1.3.48,3.9.1.2,5.3.1.6 ko:K01104,ko:K01808,ko:K20201 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA05@1239,25CRM@186801,36JRD@31979,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphotyrosine protein phosphatase JOKFNDED_04207 1396141.BATP01000005_gene6062 1.4e-30 139.4 Verrucomicrobiae ptsN 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IUWS@203494,46VMP@74201,COG1762@1,COG1762@2 NA|NA|NA GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 JOKFNDED_04208 349741.Amuc_2169 9.9e-199 699.9 Verrucomicrobiae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 2ITX2@203494,46SH6@74201,COG0018@1,COG0018@2 NA|NA|NA J Arginyl tRNA synthetase N terminal dom JOKFNDED_04211 497964.CfE428DRAFT_1407 1.3e-39 170.6 Verrucomicrobia Bacteria 46W0S@74201,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family JOKFNDED_04215 1396418.BATQ01000169_gene2673 3.3e-83 315.8 Verrucomicrobiae Bacteria 2EX0Y@1,2IVUJ@203494,33QC4@2,46UUA@74201 NA|NA|NA JOKFNDED_04221 1396418.BATQ01000073_gene503 5.9e-231 807.4 Verrucomicrobiae dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2ITPP@203494,46SG0@74201,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase alpha chain like domain JOKFNDED_04224 497964.CfE428DRAFT_4290 4.7e-137 494.6 Verrucomicrobia glgC 2.7.7.27,3.2.1.68 ko:K00975,ko:K01214 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R09995,R11261 RC00002 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 iJN678.agp,iSbBS512_1146.agp Bacteria 46SG2@74201,COG0448@1,COG0448@2 NA|NA|NA G Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family JOKFNDED_04226 1396418.BATQ01000049_gene391 2.8e-25 122.5 Verrucomicrobiae Bacteria 2IUUR@203494,46W95@74201,COG3026@1,COG3026@2 NA|NA|NA T Outer membrane lipoprotein-sorting protein JOKFNDED_04227 765910.MARPU_13855 2e-31 141.7 Chromatiales HA62_15520 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1RHNU@1224,1S4SW@1236,1WYGR@135613,COG1607@1,COG1607@2 NA|NA|NA I PFAM thioesterase superfamily JOKFNDED_04228 1396418.BATQ01000002_gene1322 5.9e-60 238.0 Verrucomicrobiae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2IW3Q@203494,46SXG@74201,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase JOKFNDED_04229 794903.OPIT5_13610 2.6e-94 352.4 Bacteria Bacteria COG2831@1,COG2831@2 NA|NA|NA U hemolysin activation secretion protein JOKFNDED_04231 102125.Xen7305DRAFT_00044210 3.4e-35 155.6 Cyanobacteria Bacteria 1GFWZ@1117,28J65@1,30UIF@2 NA|NA|NA JOKFNDED_04233 765869.BDW_01095 7.4e-14 85.1 Bdellovibrionales trwN ko:K03194,ko:K08307,ko:K08309,ko:K12089 ko03070,ko05120,map03070,map05120 M00333,M00564 ko00000,ko00001,ko00002,ko01000,ko01011,ko02044 3.A.7.12.1 GH23 Bacteria 1N5Z6@1224,2MUFS@213481,2WXTR@28221,432JU@68525,COG0741@1,COG0741@2 NA|NA|NA M Transglycosylase SLT domain JOKFNDED_04234 1341181.FLJC2902T_12990 5.5e-21 108.6 Flavobacterium Bacteria 1IDBK@117743,2E47A@1,2NXYD@237,32Z36@2,4NWDV@976 NA|NA|NA JOKFNDED_04236 1354722.JQLS01000008_gene1429 1.3e-43 184.9 Alphaproteobacteria Bacteria 1R6W3@1224,2U2GA@28211,COG3103@1,COG4991@2 NA|NA|NA T sh3 domain protein JOKFNDED_04237 460265.Mnod_8803 5e-116 424.9 Methylobacteriaceae ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1JVW0@119045,1MU3S@1224,2TT0E@28211,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family JOKFNDED_04242 497964.CfE428DRAFT_4736 2.1e-33 149.1 Verrucomicrobia ko:K07484 ko00000 Bacteria 46Z8U@74201,COG2433@1,COG2433@2 NA|NA|NA S PFAM transposase IS66 JOKFNDED_04243 497964.CfE428DRAFT_4819 1e-19 104.4 Verrucomicrobia ko:K07484 ko00000 Bacteria 46Z8U@74201,COG2433@1,COG2433@2 NA|NA|NA S PFAM transposase IS66 JOKFNDED_04244 497964.CfE428DRAFT_4735 4.1e-30 137.5 Verrucomicrobia ko:K07484 ko00000 Bacteria 46VCT@74201,COG3436@1,COG3436@2 NA|NA|NA L IS66 Orf2 like protein JOKFNDED_04245 349741.Amuc_0544 4.1e-17 97.4 Verrucomicrobiae Bacteria 2IUA3@203494,46Z1Z@74201,COG0457@1,COG0457@2,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat JOKFNDED_04249 1340493.JNIF01000004_gene734 1.4e-28 131.7 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04250 583355.Caka_0770 1.7e-99 369.8 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups JOKFNDED_04251 497964.CfE428DRAFT_5026 2.4e-10 72.8 Verrucomicrobia Bacteria 2DXTF@1,346G5@2,46W16@74201 NA|NA|NA JOKFNDED_04252 1403819.BATR01000130_gene4645 4e-220 771.9 Verrucomicrobia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 46U6N@74201,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family JOKFNDED_04253 497964.CfE428DRAFT_4944 7.1e-55 220.7 Verrucomicrobia lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 46V6W@74201,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_04257 1403819.BATR01000163_gene5458 6.6e-156 557.4 Verrucomicrobiae phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 2IU6D@203494,46TVC@74201,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase JOKFNDED_04259 240016.ABIZ01000001_gene2323 3.5e-146 525.4 Verrucomicrobiae dnaX 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2ITGI@203494,46SGC@74201,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity JOKFNDED_04260 497964.CfE428DRAFT_1755 2.2e-27 128.3 Verrucomicrobia ybaB ko:K09747 ko00000 Bacteria 46TA9@74201,COG0718@1,COG0718@2 NA|NA|NA L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection JOKFNDED_04261 1210884.HG799468_gene13692 6.5e-28 131.0 Planctomycetes Bacteria 2DMTA@1,2J4RB@203682,32TIJ@2 NA|NA|NA JOKFNDED_04263 101510.RHA1_ro00657 9.8e-09 66.2 Nocardiaceae Bacteria 2GSE1@201174,4G2S4@85025,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase JOKFNDED_04264 1173028.ANKO01000074_gene3009 1.8e-100 374.8 Oscillatoriales Bacteria 1G09B@1117,1H7M4@1150,COG0642@1,COG0745@1,COG0745@2,COG2202@1,COG2202@2,COG2205@2,COG3437@1,COG3437@2 NA|NA|NA T PhoQ Sensor JOKFNDED_04266 240016.ABIZ01000001_gene4560 6.9e-55 221.1 Verrucomicrobiae 5.2.1.8 ko:K03769,ko:K03770,ko:K03771 ko00000,ko01000,ko03110 Bacteria 2IW4M@203494,46WIC@74201,COG0760@1,COG0760@2 NA|NA|NA O PPIC-type PPIASE domain JOKFNDED_04267 1403819.BATR01000102_gene3389 5.1e-207 728.0 Verrucomicrobiae ko:K02305,ko:K08738 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 Bacteria 2IU00@203494,46TYQ@74201,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3474@1,COG3474@2,COG3828@1,COG3828@2 NA|NA|NA CG Cytochrome c JOKFNDED_04268 199310.c3470 4.5e-15 89.4 Proteobacteria Bacteria 1NVM0@1224,2F4YR@1,33XKK@2 NA|NA|NA S Psort location Cytoplasmic, score 8.96 JOKFNDED_04269 1403819.BATR01000169_gene5807 1.5e-39 169.9 Verrucomicrobia MA20_22045 ko:K06953 ko00000 Bacteria 46T8Q@74201,COG1407@1,COG1407@2 NA|NA|NA S Calcineurin-like phosphoesterase JOKFNDED_04270 1396418.BATQ01000155_gene2497 4e-47 194.9 Verrucomicrobiae pgsA 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iIT341.HP1016 Bacteria 2IUG1@203494,46VZY@74201,COG0558@1,COG0558@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase JOKFNDED_04272 1279019.ARQK01000027_gene2458 1e-188 666.4 Gammaproteobacteria ko:K06921 ko00000 Bacteria 1MWJX@1224,1RWRA@1236,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function JOKFNDED_04273 1396141.BATP01000059_gene2466 6.7e-91 340.5 Verrucomicrobiae clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2ITPB@203494,46SD6@74201,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein JOKFNDED_04275 1210884.HG799464_gene10713 3.5e-213 748.4 Planctomycetes Bacteria 2IXJ6@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04276 1403819.BATR01000020_gene657 1.8e-39 169.1 Verrucomicrobiae ko:K03088 ko00000,ko03021 Bacteria 2IVV9@203494,46VNT@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_04278 1396418.BATQ01000010_gene3794 5.2e-79 302.0 Verrucomicrobia Bacteria 2CMJG@1,32SEZ@2,46T0G@74201 NA|NA|NA JOKFNDED_04279 794903.OPIT5_03280 1.3e-09 71.2 Opitutae Bacteria 2AY1X@1,31Q3P@2,3K9QP@414999,46YJK@74201 NA|NA|NA JOKFNDED_04282 1341151.ASZU01000008_gene1530 1e-11 76.6 Bacilli Bacteria 1VY3D@1239,2DRIA@1,33BX1@2,4HX43@91061 NA|NA|NA JOKFNDED_04288 1396141.BATP01000005_gene6051 1.2e-61 244.6 Verrucomicrobiae Bacteria 2A55Z@1,2IUQ6@203494,30TUT@2,46VF8@74201 NA|NA|NA JOKFNDED_04289 1396141.BATP01000005_gene6050 1.3e-77 296.2 Verrucomicrobiae ko:K03924 ko00000,ko01000 Bacteria 2ITIT@203494,46UXC@74201,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) JOKFNDED_04290 240016.ABIZ01000001_gene2967 1.3e-48 199.9 Verrucomicrobia dhaL 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 46W0Y@74201,COG1461@1,COG1461@2 NA|NA|NA S Dak2 JOKFNDED_04291 1403819.BATR01000167_gene5725 4.8e-75 288.1 Verrucomicrobiae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU86@203494,46SVF@74201,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) JOKFNDED_04293 1403819.BATR01000112_gene3866 2.9e-80 304.7 Verrucomicrobia Bacteria 46TFQ@74201,COG0745@1,COG0745@2 NA|NA|NA T Helix-turn-helix domain JOKFNDED_04294 240016.ABIZ01000001_gene4857 2.3e-55 222.6 Verrucomicrobiae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2IU93@203494,46VAI@74201,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 JOKFNDED_04295 1396418.BATQ01000137_gene3892 9.3e-196 689.9 Verrucomicrobiae cimA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2ITQ0@203494,46S6Z@74201,COG0119@1,COG0119@2 NA|NA|NA E LeuA allosteric (dimerisation) domain JOKFNDED_04296 1396141.BATP01000017_gene2771 2.6e-115 422.2 Verrucomicrobiae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2ITSD@203494,46SBS@74201,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control JOKFNDED_04297 1123070.KB899254_gene1147 1.4e-81 310.5 Verrucomicrobiae Bacteria 2ITP8@203494,46VTV@74201,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter JOKFNDED_04298 382464.ABSI01000010_gene3537 1.1e-88 333.6 Verrucomicrobia MA20_28780 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 46SEK@74201,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family JOKFNDED_04299 344747.PM8797T_19527 1e-107 397.9 Planctomycetes 1.11.1.7,1.6.3.1 ko:K13411,ko:K19511 ko04013,ko04624,map04013,map04624 ko00000,ko00001,ko01000,ko04131 5.B.1.2 Bacteria 2J53M@203682,COG2931@1,COG2931@2 NA|NA|NA C Animal haem peroxidase JOKFNDED_04300 497964.CfE428DRAFT_0981 2.7e-71 275.8 Verrucomicrobia Bacteria 46V3J@74201,COG2133@1,COG2133@2 NA|NA|NA G Methane oxygenase PmoA JOKFNDED_04301 243090.RB728 0.0 1450.3 Planctomycetes 1.1.5.2,2.7.11.1 ko:K00117,ko:K08884,ko:K09992 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000,ko01001 Bacteria 2IWYB@203682,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type JOKFNDED_04302 794903.OPIT5_13785 3.4e-36 157.9 Bacteria Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_04304 716928.AJQT01000069_gene3455 8.8e-150 537.3 Rhizobiaceae Bacteria 1MU0K@1224,2TSFS@28211,4B7TF@82115,COG0471@1,COG0471@2 NA|NA|NA P Di- and tricarboxylate transporters JOKFNDED_04305 94122.Shewana3_3001 9.4e-51 206.1 Shewanellaceae ko:K09922 ko00000 Bacteria 1RHBQ@1224,1S7UR@1236,2QBWQ@267890,COG3169@1,COG3169@2 NA|NA|NA S Putative member of DMT superfamily (DUF486) JOKFNDED_04307 1396418.BATQ01000155_gene2477 7e-135 487.3 Verrucomicrobiae Bacteria 2IWKK@203494,46V0A@74201,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase JOKFNDED_04308 243090.RB1574 6.3e-132 477.2 Planctomycetes 5.1.3.22,5.3.1.5 ko:K01805,ko:K03079 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R00878,R01432,R03244 RC00376,RC00516,RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXRD@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_04309 909663.KI867150_gene2392 1.3e-79 303.5 Syntrophobacterales arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011,ko:K12449,ko:K21332 ko00052,ko00520,ko00523,ko01100,ko01130,ko01503,map00052,map00520,map00523,map01100,map01130,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R01384,R01386,R02984,R07658,R07660,R11472 RC00026,RC00289,RC00508,RC01575,RC01811,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 iPC815.YPO2420,iSFV_1184.SFV_2325 Bacteria 1MXKV@1224,2MR30@213462,2WIRV@28221,42QC6@68525,COG0451@1,COG0451@2 NA|NA|NA GM 3-beta hydroxysteroid dehydrogenase/isomerase family JOKFNDED_04310 1041159.AZUW01000038_gene2714 1.4e-26 125.9 Proteobacteria Bacteria 1R02V@1224,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 JOKFNDED_04311 1244869.H261_13549 1.5e-94 352.8 Rhodospirillales gluQ 6.1.1.17 ko:K01885,ko:K01894 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 1MUN7@1224,2JPHU@204441,2TR2V@28211,COG0008@1,COG0008@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family JOKFNDED_04313 1396418.BATQ01000181_gene833 1.1e-296 1026.2 Verrucomicrobia tolB ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 46T85@74201,COG0265@1,COG0265@2,COG0823@1,COG0823@2,COG2234@1,COG2234@2 NA|NA|NA OU PA domain JOKFNDED_04314 1403819.BATR01000093_gene2897 1.9e-137 496.9 Verrucomicrobiae ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2ITGX@203494,46TXY@74201,COG0457@1,COG0457@2,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II and III secretion system protein JOKFNDED_04315 1396418.BATQ01000046_gene6110 1e-238 832.8 Verrucomicrobiae korA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2IV6Q@203494,46SM9@74201,COG0674@1,COG0674@2 NA|NA|NA C Pyruvate:ferredoxin oxidoreductase core domain II JOKFNDED_04316 1403819.BATR01000181_gene6237 2.1e-126 458.8 Verrucomicrobiae korB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2IV9I@203494,46SRY@74201,COG1013@1,COG1013@2 NA|NA|NA C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain JOKFNDED_04317 240016.ABIZ01000001_gene1546 2.3e-07 61.2 Verrucomicrobiae xylB 1.1.1.57,2.7.1.17 ko:K00040,ko:K00854,ko:K19168 ko00040,ko01100,map00040,map01100 M00014,M00061 R01639,R02454 RC00002,RC00085,RC00538 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 2IUMH@203494,46SI1@74201,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, C-terminal domain JOKFNDED_04318 497964.CfE428DRAFT_6142 1.3e-50 206.5 Verrucomicrobia MA20_05800 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K09778 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT30 Bacteria 46SZ0@74201,COG2121@1,COG2121@2 NA|NA|NA S Domain of unknown function (DUF374) JOKFNDED_04320 240016.ABIZ01000001_gene2026 3.5e-239 834.7 Verrucomicrobiae 5.1.3.37 ko:K01795,ko:K20276 ko00051,ko02024,map00051,map02024 R08693 RC00509 ko00000,ko00001,ko01000 Bacteria 2IUWR@203494,46TGV@74201,COG3420@1,COG3420@2 NA|NA|NA P Right handed beta helix region JOKFNDED_04321 240016.ABIZ01000001_gene3275 1.2e-64 253.8 Bacteria rlmM GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 ko:K06968 ko00000,ko01000,ko03009 Bacteria COG2933@1,COG2933@2 NA|NA|NA J rRNA processing JOKFNDED_04322 240016.ABIZ01000001_gene1539 4.1e-74 285.4 Verrucomicrobia Bacteria 46TV4@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_04323 314230.DSM3645_16455 1.8e-79 302.4 Planctomycetes Bacteria 2IZRN@203682,COG4188@1,COG4188@2 NA|NA|NA S dienelactone hydrolase JOKFNDED_04324 240016.ABIZ01000001_gene482 2e-77 296.2 Verrucomicrobiae 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IVXQ@203494,46T1J@74201,COG2870@1,COG2870@2 NA|NA|NA M pfkB family carbohydrate kinase JOKFNDED_04325 1403819.BATR01000051_gene1549 5.2e-54 217.6 Verrucomicrobiae gmhA 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2IUZI@203494,46SXU@74201,COG0279@1,COG0279@2 NA|NA|NA G SIS domain JOKFNDED_04327 240016.ABIZ01000001_gene4782 1.3e-28 132.1 Verrucomicrobiae nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2ITYB@203494,46S8J@74201,COG1894@1,COG1894@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region JOKFNDED_04328 1396141.BATP01000003_gene5062 6.1e-217 760.4 Verrucomicrobiae nuoG 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2ITJ1@203494,46S6S@74201,COG1034@1,COG1034@2,COG3383@1,COG3383@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region JOKFNDED_04329 1396418.BATQ01000155_gene2466 6.5e-140 503.8 Verrucomicrobiae nuoH 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2ITZ1@203494,46SIJ@74201,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone JOKFNDED_04330 1403819.BATR01000084_gene2445 9.2e-71 273.1 Verrucomicrobiae nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00338,ko:K02573 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IU68@203494,46SNT@74201,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient JOKFNDED_04331 497964.CfE428DRAFT_0531 1.1e-28 133.3 Verrucomicrobia nuoJ 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 46VSH@74201,COG0839@1,COG0839@2 NA|NA|NA C NADH-ubiquinone/plastoquinone oxidoreductase chain 6 JOKFNDED_04332 497964.CfE428DRAFT_0532 1.5e-31 142.1 Verrucomicrobia nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 46SX4@74201,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient JOKFNDED_04333 240016.ABIZ01000001_gene4772 4.7e-175 621.3 Verrucomicrobiae nuoL 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2ITQ9@203494,46SDU@74201,COG1009@1,COG1009@2 NA|NA|NA CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus JOKFNDED_04334 497964.CfE428DRAFT_0536 1.8e-135 489.6 Verrucomicrobia ndhD 1.6.5.3 ko:K00342,ko:K05575 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iJN678.ndhD2 Bacteria 46SE4@74201,COG1008@1,COG1008@2 NA|NA|NA C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M JOKFNDED_04340 1380390.JIAT01000011_gene2883 1.1e-10 74.7 Rubrobacteria flgK GO:0005575,GO:0005576 3.2.1.97,4.1.3.1 ko:K01637,ko:K02388,ko:K02396,ko:K03932,ko:K07004,ko:K17624 ko00630,ko01100,ko01110,ko01120,ko01200,ko02040,map00630,map01100,map01110,map01120,map01200,map02040 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000,ko02035 CE1,GH101 Bacteria 2I2X3@201174,4CSIX@84995,COG0028@1,COG0028@2,COG0515@1,COG0515@2,COG1409@1,COG1409@2,COG1749@1,COG1749@2,COG2374@1,COG2374@2,COG3291@1,COG3291@2,COG3509@1,COG3509@2,COG4733@1,COG4733@2 NA|NA|NA N Fibronectin type 3 domain JOKFNDED_04342 211165.AJLN01000084_gene1818 6.8e-30 138.7 Stigonemataceae Bacteria 1GFJ1@1117,1JM05@1189,2EMH7@1,33F5U@2 NA|NA|NA JOKFNDED_04343 497964.CfE428DRAFT_1448 9.6e-57 226.9 Verrucomicrobia pcpC 2.5.1.18 ko:K00799,ko:K15241 ko00361,ko00480,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418 R03522,R05402,R05403,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01363,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 46SQB@74201,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain JOKFNDED_04344 686340.Metal_3033 9.8e-87 326.6 Methylococcales Bacteria 1MW9A@1224,1RMMZ@1236,1XG2S@135618,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM short chain dehydrogenase JOKFNDED_04345 1403819.BATR01000146_gene4993 2.6e-76 292.4 Bacteria 1.1.1.169,1.5.1.28 ko:K00077,ko:K04940 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria COG1893@1,COG1893@2 NA|NA|NA H 2-dehydropantoate 2-reductase activity JOKFNDED_04347 438753.AZC_1300 1.2e-61 243.8 Xanthobacteraceae Bacteria 1MXVQ@1224,2U16F@28211,3F0D2@335928,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase JOKFNDED_04348 1038858.AXBA01000011_gene1530 2.2e-46 192.6 Xanthobacteraceae ko:K02477 ko00000,ko02022 Bacteria 1MUE8@1224,2TSPC@28211,3F1FG@335928,COG3279@1,COG3279@2 NA|NA|NA T LytTr DNA-binding domain JOKFNDED_04353 314230.DSM3645_11242 3.2e-53 215.3 Planctomycetes Bacteria 2IXKN@203682,COG1520@1,COG1520@2 NA|NA|NA S COG1520 FOG WD40-like repeat JOKFNDED_04354 452637.Oter_4589 1.8e-11 74.7 Opitutae Bacteria 2E99J@1,333HQ@2,3K8CU@414999,46T77@74201 NA|NA|NA JOKFNDED_04356 1123070.KB899248_gene156 5.6e-53 213.8 Verrucomicrobiae gnnA ko:K09949 ko00000 iAF987.Gmet_2352 Bacteria 2IU1W@203494,46SAE@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_04357 1403819.BATR01000169_gene5806 1.6e-188 665.6 Verrucomicrobiae lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2ITHH@203494,46TIA@74201,COG1190@1,COG1190@2 NA|NA|NA J tRNA synthetases class II (D, K and N) JOKFNDED_04358 1121448.DGI_2963 5.3e-45 188.7 Deltaproteobacteria ppsR 2.1.1.80,2.7.13.3,3.1.1.61 ko:K02030,ko:K03406,ko:K07679,ko:K13924 ko02020,ko02030,ko05133,map02020,map02030,map05133 M00236,M00477,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035 3.A.1.3 Bacteria 1NWNJ@1224,2X860@28221,43BSA@68525,COG0834@1,COG0834@2,COG2202@1,COG2202@2,COG3829@1,COG3829@2 NA|NA|NA T PAS domain JOKFNDED_04359 1396141.BATP01000002_gene4830 3.9e-131 474.6 Verrucomicrobiae hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITPG@203494,46S91@74201,COG0113@1,COG0113@2 NA|NA|NA H Delta-aminolevulinic acid dehydratase JOKFNDED_04360 349741.Amuc_1031 4e-161 574.7 Verrucomicrobiae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c Bacteria 2ITI3@203494,46SES@74201,COG0215@1,COG0215@2 NA|NA|NA J tRNA synthetases class I (C) catalytic domain JOKFNDED_04364 756272.Plabr_3627 1.8e-90 339.7 Planctomycetes Bacteria 2IZH6@203682,COG2133@1,COG2133@2 NA|NA|NA G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella JOKFNDED_04365 240016.ABIZ01000001_gene5226 2.9e-250 872.1 Verrucomicrobiae Bacteria 2IV2Y@203494,46TXK@74201,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG lipolytic protein G-D-S-L family JOKFNDED_04366 240016.ABIZ01000001_gene5225 1.9e-64 253.1 Bacteria Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family JOKFNDED_04367 945713.IALB_0547 4.9e-44 184.1 Bacteria 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria COG2406@1,COG2406@2 NA|NA|NA S Ferritin, Dps family protein JOKFNDED_04368 240016.ABIZ01000001_gene132 0.0 1265.4 Verrucomicrobiae Bacteria 2IWNV@203494,46TNB@74201,COG1020@1,COG1020@2 NA|NA|NA Q Protein of unknown function (DUF1587) JOKFNDED_04370 1396418.BATQ01000186_gene2152 4.6e-223 780.4 Bacteria Bacteria COG2960@1,COG2960@2 NA|NA|NA M long-chain fatty acid transporting porin activity JOKFNDED_04371 1403819.BATR01000027_gene895 4.8e-182 644.0 Bacteria Bacteria 28MZ7@1,33R3K@2 NA|NA|NA JOKFNDED_04372 1123242.JH636435_gene3079 1.7e-157 562.8 Planctomycetes Bacteria 2J1X7@203682,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_04373 880070.Cycma_4329 7.3e-76 291.2 Bacteroidetes Bacteria 4P1JJ@976,COG4409@1,COG4409@2 NA|NA|NA G BNR/Asp-box repeat JOKFNDED_04374 497964.CfE428DRAFT_4754 1.3e-173 616.3 Verrucomicrobia Bacteria 46UET@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_04375 1403819.BATR01000118_gene4167 1.8e-107 396.0 Verrucomicrobiae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 ko:K03621,ko:K21576,ko:K21577 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2ITU1@203494,46S8C@74201,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA JOKFNDED_04376 1396418.BATQ01000109_gene4742 3.5e-14 83.6 Verrucomicrobiae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IV03@203494,46TCD@74201,COG0333@1,COG0333@2 NA|NA|NA J Ribosomal L32p protein family JOKFNDED_04377 1396418.BATQ01000045_gene6085 8.4e-103 380.9 Bacteria Bacteria COG3712@1,COG3712@2 NA|NA|NA PT iron ion homeostasis JOKFNDED_04378 1403819.BATR01000182_gene6262 1.7e-59 235.7 Bacteria rfaY ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_04384 344747.PM8797T_19091 1.4e-79 303.1 Planctomycetes glkA 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IY6I@203682,COG1940@1,COG1940@2 NA|NA|NA GK PFAM ROK family JOKFNDED_04385 1442599.JAAN01000033_gene1641 9.9e-30 137.1 Xanthomonadales 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183 ko00500,ko00520,ko01100,map00500,map00520,map01100 R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 GH18,GH5,GH9 Bacteria 1RBFJ@1224,1SEW9@1236,1X661@135614,COG2755@1,COG2755@2 NA|NA|NA E COG2755 Lysophospholipase L1 and related esterases JOKFNDED_04386 278963.ATWD01000001_gene2662 4.1e-13 80.5 Bacteria Bacteria COG2886@1,COG2886@2 NA|NA|NA E Uncharacterised protein family (UPF0175) JOKFNDED_04387 69014.TK0918 6.6e-23 114.0 Thermococci ko:K07066 ko00000 Archaea 2448Z@183968,2Y0GG@28890,COG2405@1,arCOG00717@2157 NA|NA|NA V Domain of unknown function (DUF3368) JOKFNDED_04388 1396141.BATP01000049_gene3498 7.4e-187 660.6 Verrucomicrobiae ko:K03305 ko00000 2.A.17 Bacteria 2IU1T@203494,46UAC@74201,COG3104@1,COG3104@2 NA|NA|NA E POT family JOKFNDED_04389 1403819.BATR01000096_gene3176 6.2e-125 454.5 Verrucomicrobiae exeA ko:K02450 M00331 ko00000,ko00002,ko02044 9.B.42 Bacteria 2ITKF@203494,46XUJ@74201,COG3271@1,COG3271@2 NA|NA|NA S Peptidase_C39 like family JOKFNDED_04390 344747.PM8797T_15341 7.5e-92 344.4 Bacteria Bacteria 2DV29@1,33TNQ@2 NA|NA|NA S Periplasmic copper-binding protein (NosD) JOKFNDED_04391 234267.Acid_4818 1.2e-101 377.1 Bacteria Bacteria COG0673@1,COG0673@2 NA|NA|NA S inositol 2-dehydrogenase activity JOKFNDED_04392 530564.Psta_3458 2.9e-61 241.9 Planctomycetes ko:K09004 ko00000 Bacteria 2IZ87@203682,COG1416@1,COG1416@2,COG4798@1,COG4798@2 NA|NA|NA S PFAM Methyltransferase type 11 JOKFNDED_04393 1158345.JNLL01000001_gene228 4.8e-28 131.3 Aquificae Bacteria 2G52S@200783,COG1472@1,COG1472@2 NA|NA|NA G Protein of unknown function (DUF3365) JOKFNDED_04394 375286.mma_2596 2.1e-74 285.4 Oxalobacteraceae cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1NGFN@1224,2VUIT@28216,476WJ@75682,COG0288@1,COG0288@2 NA|NA|NA H Reversible hydration of carbon dioxide JOKFNDED_04395 314230.DSM3645_28757 1.6e-83 315.8 Bacteria Bacteria 2E958@1,333E0@2 NA|NA|NA JOKFNDED_04396 1200792.AKYF01000006_gene1410 3.4e-15 89.4 Bacilli Bacteria 1V1QY@1239,28XGS@1,2ZJE7@2,4HGQC@91061 NA|NA|NA JOKFNDED_04397 1396418.BATQ01000029_gene5645 1.3e-84 319.7 Verrucomicrobiae MA20_23385 ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVIA@203494,46UQ0@74201,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter JOKFNDED_04398 1403819.BATR01000069_gene2079 1.1e-82 313.2 Verrucomicrobiae MA20_23390 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVD6@203494,46UP6@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_04399 1123070.KB899254_gene1190 5e-274 950.7 Verrucomicrobiae ywqA 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2ITR2@203494,46TSJ@74201,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain JOKFNDED_04400 1403819.BATR01000005_gene171 2.5e-73 282.0 Verrucomicrobiae Bacteria 2IUBA@203494,46UAQ@74201,COG1082@1,COG1082@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG3241@1,COG3241@2 NA|NA|NA CG pyrroloquinoline quinone binding JOKFNDED_04402 344747.PM8797T_05985 1.8e-66 260.0 Planctomycetes Bacteria 2J4YR@203682,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family JOKFNDED_04403 1123242.JH636435_gene2797 7e-124 451.1 Planctomycetes peaA 1.4.9.1 ko:K08685 ko00680,ko01120,map00680,map01120 R00606 RC00189 ko00000,ko00001,ko01000 Bacteria 2J547@203682,COG2010@1,COG2010@2 NA|NA|NA C PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain JOKFNDED_04404 1123242.JH636435_gene2796 6.1e-24 117.5 Bacteria Bacteria COG1225@1,COG1225@2 NA|NA|NA O peroxiredoxin activity JOKFNDED_04405 1403819.BATR01000090_gene2617 2.1e-105 389.4 Verrucomicrobia Bacteria 46TM3@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_04406 243090.RB273 4.1e-93 347.8 Planctomycetes Bacteria 2J01Q@203682,COG2152@1,COG2152@2 NA|NA|NA G Domain of Unknown Function (DUF1080) JOKFNDED_04407 794903.OPIT5_13610 1.1e-86 327.8 Bacteria Bacteria COG2831@1,COG2831@2 NA|NA|NA U hemolysin activation secretion protein JOKFNDED_04409 497964.CfE428DRAFT_4105 1.2e-55 223.4 Verrucomicrobia ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 46UBH@74201,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family JOKFNDED_04410 497964.CfE428DRAFT_4106 3e-22 112.1 Verrucomicrobia Bacteria 2FBR0@1,343VW@2,46W55@74201 NA|NA|NA T Domain present in phytochromes and cGMP-specific phosphodiesterases. JOKFNDED_04412 1286631.X805_30560 1.1e-15 91.7 unclassified Burkholderiales Bacteria 1KNYS@119065,1NDH4@1224,2E3WQ@1,2VWRA@28216,32YTW@2 NA|NA|NA JOKFNDED_04414 1205680.CAKO01000040_gene1087 1.5e-12 80.9 Alphaproteobacteria bepF ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MU78@1224,2TT21@28211,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_04415 595460.RRSWK_07204 2.1e-45 189.1 Planctomycetes Bacteria 2IYQ3@203682,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_04416 794903.OPIT5_05465 1.1e-11 75.5 Opitutae Bacteria 3K8AC@414999,46T08@74201,COG0614@1,COG0614@2 NA|NA|NA P PD-(D/E)XK nuclease superfamily JOKFNDED_04417 1396141.BATP01000039_gene1332 6.1e-09 65.9 Verrucomicrobiae Bacteria 2IW30@203494,46VQG@74201,COG0614@1,COG0614@2 NA|NA|NA P PD-(D/E)XK nuclease superfamily JOKFNDED_04418 1396141.BATP01000027_gene1129 1.8e-50 207.2 Bacteria Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity JOKFNDED_04419 1403819.BATR01000157_gene5212 2.2e-11 74.7 Verrucomicrobiae Bacteria 2AW5E@1,2IUYR@203494,31N0D@2,46X83@74201 NA|NA|NA JOKFNDED_04420 570952.ATVH01000011_gene324 1.6e-141 510.0 Rhodospirillales Bacteria 1MU0K@1224,2JQMU@204441,2TSFS@28211,COG0471@1,COG0471@2 NA|NA|NA P TrkA-C domain JOKFNDED_04421 504472.Slin_3376 1.9e-08 65.1 Cytophagia ypeB 2.7.7.7 ko:K02342,ko:K09954,ko:K10857 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47RWJ@768503,4NUSP@976,COG3530@1,COG3530@2 NA|NA|NA S Putative quorum-sensing-regulated virulence factor JOKFNDED_04423 1031711.RSPO_c02980 1.1e-17 97.1 Burkholderiaceae yajR Bacteria 1K03E@119060,1MVSH@1224,2VITN@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily JOKFNDED_04424 1396418.BATQ01000041_gene6273 6.2e-08 64.7 Bacteria Bacteria 2EG0U@1,339SV@2 NA|NA|NA JOKFNDED_04426 153721.MYP_339 2.8e-07 62.8 Bacteria Bacteria 2FFF2@1,347CN@2 NA|NA|NA JOKFNDED_04428 579405.Dd703_0310 3.4e-08 64.7 Dickeya Bacteria 1NFW0@1224,1SCTP@1236,2E55H@1,2JF5S@204037,32ZYD@2 NA|NA|NA S Immunity protein 8 JOKFNDED_04430 1121035.AUCH01000019_gene2827 1.6e-36 159.5 Proteobacteria Bacteria 1N32C@1224,2CWJP@1,32SZU@2 NA|NA|NA JOKFNDED_04432 497964.CfE428DRAFT_0339 1.2e-25 122.5 Verrucomicrobia hemD GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.5.1.61,4.2.1.75,4.99.1.4 ko:K01719,ko:K01749,ko:K02302,ko:K02303,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS15755,iJN678.hemD,iYO844.BSU15610 Bacteria 46S9P@74201,COG0007@1,COG0007@2,COG1587@1,COG1587@2 NA|NA|NA H Belongs to the precorrin methyltransferase family JOKFNDED_04433 1396418.BATQ01000020_gene5017 1.5e-72 280.0 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_04436 240016.ABIZ01000001_gene4821 2e-134 485.7 Verrucomicrobiae hemD GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.5.1.61,4.2.1.75,4.99.1.4 ko:K01719,ko:K01749,ko:K02302,ko:K02303,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS15755,iJN678.hemD,iYO844.BSU15610 Bacteria 2ITRR@203494,46S9P@74201,COG0007@1,COG0007@2,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase HemD JOKFNDED_04437 530564.Psta_2043 1e-51 209.5 Planctomycetes 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 2IZQG@203682,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen JOKFNDED_04438 756272.Plabr_3132 1.2e-120 440.7 Planctomycetes Bacteria 28I6K@1,2IZZZ@203682,2Z89I@2 NA|NA|NA JOKFNDED_04439 65393.PCC7424_0177 3.1e-49 202.6 Cyanothece Bacteria 1G3N4@1117,28J0S@1,2Z8XX@2,3KHGW@43988 NA|NA|NA JOKFNDED_04440 344747.PM8797T_24046 5.6e-198 697.2 Planctomycetes Bacteria 2IXIE@203682,COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase A JOKFNDED_04441 1396418.BATQ01000141_gene3394 1.2e-36 161.0 Bacteria Bacteria COG1376@1,COG1376@2 NA|NA|NA D ErfK ybiS ycfS ynhG family protein JOKFNDED_04442 497964.CfE428DRAFT_4105 2.2e-63 249.2 Verrucomicrobia ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 46UBH@74201,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family JOKFNDED_04443 497964.CfE428DRAFT_4106 5.7e-18 97.8 Verrucomicrobia Bacteria 2FBR0@1,343VW@2,46W55@74201 NA|NA|NA T Domain present in phytochromes and cGMP-specific phosphodiesterases. JOKFNDED_04444 344747.PM8797T_03419 5.2e-198 697.6 Bacteria 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_04445 756272.Plabr_3163 4e-96 358.2 Bacteria Bacteria COG1957@1,COG1957@2 NA|NA|NA F ribosylpyrimidine nucleosidase activity JOKFNDED_04446 756272.Plabr_3156 3.4e-90 338.6 Planctomycetes Bacteria 2IYE3@203682,COG1957@1,COG1957@2 NA|NA|NA F COG1957 Inosine-uridine nucleoside N-ribohydrolase JOKFNDED_04447 1137799.GZ78_27415 1.9e-07 61.6 Gammaproteobacteria Bacteria 1NIP4@1224,1T1CI@1236,2AGQ6@1,316XW@2 NA|NA|NA JOKFNDED_04448 391735.Veis_0177 7.9e-30 136.7 Proteobacteria Bacteria 1QZUI@1224,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_04449 344747.PM8797T_01064 1.3e-78 300.1 Planctomycetes rbsC ko:K10440 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2IZWQ@203682,COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family JOKFNDED_04450 756272.Plabr_3159 6.4e-76 290.8 Planctomycetes rbsB ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2J2R0@203682,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain JOKFNDED_04454 1396418.BATQ01000175_gene2741 1.8e-79 302.4 Verrucomicrobiae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2ITPQ@203494,46SNG@74201,COG0052@1,COG0052@2 NA|NA|NA J Ribosomal protein S2 JOKFNDED_04455 1396141.BATP01000023_gene533 0.0 1577.4 Verrucomicrobiae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2ITYC@203494,46S79@74201,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates JOKFNDED_04456 240016.ABIZ01000001_gene4739 1.2e-24 119.0 Verrucomicrobiae lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITJM@203494,46SIS@74201,COG0527@1,COG0527@2 NA|NA|NA E Amino acid kinase family JOKFNDED_04457 1249627.D779_3026 1.6e-148 532.7 Chromatiales rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MU49@1224,1RMWA@1236,1WXQZ@135613,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family JOKFNDED_04458 240016.ABIZ01000001_gene4734 2e-91 342.8 Verrucomicrobiae Bacteria 2IVJ1@203494,46ZKM@74201,COG3182@1,COG3182@2 NA|NA|NA S PepSY-associated TM region JOKFNDED_04459 1381123.AYOD01000013_gene2206 2.3e-160 572.8 Phyllobacteriaceae fhuA ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QTT0@1224,2TQSQ@28211,43IIB@69277,COG4773@1,COG4773@2 NA|NA|NA P TonB-dependent Receptor Plug Domain JOKFNDED_04460 1121918.ARWE01000001_gene2175 4.6e-69 268.9 Desulfuromonadales Bacteria 1MUB7@1224,2WK6I@28221,42PT6@68525,43S53@69541,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 JOKFNDED_04461 1121921.KB898707_gene694 3.4e-99 368.6 Gammaproteobacteria 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUKZ@1224,1RPBK@1236,COG2706@1,COG2706@2 NA|NA|NA G COG2706 3-carboxymuconate cyclase JOKFNDED_04462 1403819.BATR01000085_gene2455 4e-130 471.1 Verrucomicrobiae trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K03671,ko:K22345 ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913,iPC815.YPO1374 Bacteria 2ITP4@203494,46SC1@74201,COG0492@1,COG0492@2 NA|NA|NA O Pyridine nucleotide-disulphide oxidoreductase JOKFNDED_04464 351016.RAZWK3B_12257 9.8e-68 264.2 Roseobacter 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1MUKB@1224,2P1FF@2433,2TR6A@28211,COG0415@1,COG0415@2 NA|NA|NA L COG0415 Deoxyribodipyrimidine photolyase JOKFNDED_04467 1423755.BAML01000035_gene1497 5.5e-59 234.2 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate JOKFNDED_04468 497964.CfE428DRAFT_2530 2.4e-114 419.1 Verrucomicrobia Bacteria 46UY1@74201,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase JOKFNDED_04469 344747.PM8797T_25651 1.1e-53 216.5 Planctomycetes Bacteria 2J2M0@203682,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase JOKFNDED_04471 278957.ABEA03000217_gene377 2.4e-21 108.6 Opitutae Bacteria 3K872@414999,46VNQ@74201,COG1959@1,COG1959@2 NA|NA|NA K TIGRFAM transcriptional regulator, Rrf2 family JOKFNDED_04473 1396141.BATP01000057_gene2979 2.8e-173 615.5 Verrucomicrobiae pgi 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2ITZ9@203494,46SUH@74201,COG0166@1,COG0166@2 NA|NA|NA G Phosphoglucose isomerase JOKFNDED_04474 986075.CathTA2_2241 3.4e-180 638.3 Bacilli lldP ko:K03303 ko00000,ko02000 2.A.14 Bacteria 1TQNM@1239,4HAF3@91061,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease JOKFNDED_04476 1396418.BATQ01000133_gene4091 1.7e-120 439.5 Verrucomicrobiae ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 2IU82@203494,46S6D@74201,COG2239@1,COG2239@2 NA|NA|NA P Divalent cation transporter JOKFNDED_04477 452637.Oter_0993 8.8e-45 188.0 Opitutae Bacteria 2E1EI@1,32WTG@2,3K94I@414999,46T04@74201 NA|NA|NA JOKFNDED_04478 595460.RRSWK_04606 3.3e-49 202.6 Bacteria ko:K06889 ko00000 Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity JOKFNDED_04479 1123242.JH636434_gene3172 1.2e-277 963.0 Planctomycetes Bacteria 2IYIY@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04480 278957.ABEA03000050_gene166 1e-35 156.4 Verrucomicrobia Bacteria 2DX9U@1,3441M@2,46WED@74201 NA|NA|NA JOKFNDED_04483 583355.Caka_1337 7e-238 830.1 Opitutae parE 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 3K7SG@414999,46SEN@74201,COG0187@1,COG0187@2 NA|NA|NA L DNA topoisomerase type IIA subunit B region 2 domain protein JOKFNDED_04484 1403819.BATR01000171_gene5844 6.8e-22 112.8 Verrucomicrobiae Bacteria 2E7EH@1,2IW5Y@203494,32BRB@2,46Z47@74201 NA|NA|NA JOKFNDED_04485 583355.Caka_2931 6.2e-155 554.3 Opitutae ko:K06610,ko:K08369 ko00000,ko02000 2.A.1,2.A.1.1.27 Bacteria 3K9UU@414999,46TFW@74201,COG0738@1,COG0738@2 NA|NA|NA G PFAM major facilitator superfamily MFS_1 JOKFNDED_04486 1396418.BATQ01000088_gene1042 1.5e-29 135.6 Verrucomicrobiae arsC 1.20.4.1 ko:K00537 ko00000,ko01000 Bacteria 2IUPM@203494,46VTP@74201,COG1393@1,COG1393@2 NA|NA|NA P ArsC family JOKFNDED_04487 1028801.RG1141_PA07630 4.8e-20 105.1 Rhizobiaceae hpaI 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 Bacteria 1MUSG@1224,2TT2W@28211,4B76M@82115,COG3836@1,COG3836@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family JOKFNDED_04488 1396418.BATQ01000171_gene2983 8.1e-170 603.6 Verrucomicrobia Bacteria 46TMN@74201,COG3356@1,COG3356@2 NA|NA|NA S PFAM Neutral alkaline nonlysosomal ceramidase JOKFNDED_04489 1396141.BATP01000025_gene926 1.5e-89 337.0 Verrucomicrobiae Bacteria 2IU8E@203494,46Z7G@74201,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold JOKFNDED_04490 497964.CfE428DRAFT_0051 1.5e-41 177.6 Verrucomicrobia 5.2.1.8 ko:K03770,ko:K07533 ko00000,ko01000,ko03110 Bacteria 46T1I@74201,COG0760@1,COG0760@2 NA|NA|NA O PPIC-type PPIASE domain JOKFNDED_04491 1396141.BATP01000024_gene815 2.2e-22 111.7 Verrucomicrobiae pilF ko:K02656 ko00000,ko02035,ko02044 Bacteria 2IUK3@203494,46T56@74201,COG3063@1,COG3063@2 NA|NA|NA NU Tetratricopeptide repeat JOKFNDED_04492 1396418.BATQ01000145_gene3536 1.6e-268 932.6 Verrucomicrobiae Bacteria 2IV63@203494,46U0M@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) JOKFNDED_04493 1403819.BATR01000176_gene5940 3.7e-194 684.5 Verrucomicrobia Bacteria 46UQM@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04495 349741.Amuc_1417 2.3e-123 448.7 Verrucomicrobiae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2ITXT@203494,46S59@74201,COG0057@1,COG0057@2 NA|NA|NA G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain JOKFNDED_04497 1123070.KB899254_gene1157 4.1e-80 304.7 Verrucomicrobiae rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2ITNM@203494,46U55@74201,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates JOKFNDED_04498 1396418.BATQ01000026_gene5284 1.1e-124 453.4 Verrucomicrobiae lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 Bacteria 2ITPT@203494,46SBI@74201,COG1663@1,COG1663@2 NA|NA|NA M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) JOKFNDED_04499 240016.ABIZ01000001_gene2724 9.2e-26 123.6 Verrucomicrobiae yqgC ko:K09793 ko00000 Bacteria 2IUVN@203494,46WEX@74201,COG2839@1,COG2839@2 NA|NA|NA S Protein of unknown function (DUF456) JOKFNDED_04500 575540.Isop_1944 8.1e-73 280.4 Planctomycetes Bacteria 2IY1J@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04501 314230.DSM3645_16265 2.8e-207 728.0 Planctomycetes Bacteria 2IXKP@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04503 240016.ABIZ01000001_gene699 4.7e-43 181.4 Verrucomicrobiae 2.7.7.13,5.4.2.8 ko:K00966,ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUEW@203494,46SP1@74201,COG1208@1,COG1208@2 NA|NA|NA JM Hexapeptide repeat of succinyl-transferase JOKFNDED_04504 349741.Amuc_1318 4.1e-53 214.5 Verrucomicrobiae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2IUA0@203494,46V49@74201,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another JOKFNDED_04505 1403819.BATR01000057_gene1782 4.7e-94 350.9 Verrucomicrobiae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2ITVK@203494,46S4W@74201,COG0528@1,COG0528@2 NA|NA|NA F Amino acid kinase family JOKFNDED_04506 1403819.BATR01000017_gene547 7.7e-84 317.4 Verrucomicrobiae fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 2ITWX@203494,46SKS@74201,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus JOKFNDED_04508 314230.DSM3645_20552 1.1e-153 550.4 Planctomycetes Bacteria 2J52G@203682,COG0400@1,COG0400@2 NA|NA|NA S Alpha/beta hydrolase family JOKFNDED_04509 497964.CfE428DRAFT_4278 7.2e-39 167.5 Verrucomicrobia Bacteria 46T00@74201,COG2866@1,COG2866@2 NA|NA|NA E Succinylglutamate desuccinylase / Aspartoacylase family JOKFNDED_04510 1403819.BATR01000117_gene4026 2.4e-295 1021.5 Verrucomicrobiae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IVJE@203494,46SD1@74201,COG2010@1,COG2010@2,COG5492@1,COG5492@2 NA|NA|NA N Protein of unknown function (DUF1549) JOKFNDED_04511 886293.Sinac_5683 4.5e-160 572.0 Planctomycetes Bacteria 2IWVN@203682,COG3064@1,COG3064@2 NA|NA|NA M Membrane JOKFNDED_04512 344747.PM8797T_03945 2.3e-171 608.6 Planctomycetes Bacteria 2IWYX@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04513 1396418.BATQ01000113_gene4694 5e-72 280.0 Verrucomicrobiae Bacteria 2IV42@203494,46UIQ@74201,COG2319@1,COG2319@2 NA|NA|NA S WD domain, G-beta repeat JOKFNDED_04514 1210884.HG799476_gene15378 7.3e-117 427.6 Planctomycetes Bacteria 2IWZW@203682,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_04515 314230.DSM3645_01831 5.5e-203 714.1 Planctomycetes 3.4.24.3 ko:K01138,ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria 2IYFZ@203682,COG1413@1,COG1413@2,COG3119@1,COG3119@2 NA|NA|NA CP COG3119 Arylsulfatase A JOKFNDED_04520 626887.J057_18960 1.5e-258 898.7 Alteromonadaceae mod 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1MX9M@1224,1RNHM@1236,46999@72275,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase JOKFNDED_04521 232346.JHQL01000004_gene1673 0.0 1178.7 Oceanospirillales 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1MX92@1224,1RYDV@1236,1XJVR@135619,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit JOKFNDED_04525 1123070.KB899256_gene2208 1.8e-56 226.9 Bacteria ko:K06919 ko00000 Bacteria COG0467@1,COG0467@2 NA|NA|NA T regulation of circadian rhythm JOKFNDED_04527 1396418.BATQ01000180_gene3014 4.7e-100 371.3 Verrucomicrobia Bacteria 46TD6@74201,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family JOKFNDED_04528 1121013.P873_00390 6.8e-64 250.8 Proteobacteria ko:K03969 ko00000 Bacteria 1NNUD@1224,COG1842@1,COG1842@2 NA|NA|NA KT PspA/IM30 family JOKFNDED_04531 521674.Plim_0263 1.1e-295 1022.7 Planctomycetes ctpF GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.8 ko:K01537,ko:K12953 ko00000,ko01000 3.A.3,3.A.3.2 Bacteria 2IXV7@203682,COG0474@1,COG0474@2 NA|NA|NA P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC JOKFNDED_04532 1396141.BATP01000036_gene3827 1.4e-113 416.8 Verrucomicrobiae ydcR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 2.7.7.65 ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Bacteria 2IVDB@203494,46STK@74201,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase class I and II JOKFNDED_04533 240016.ABIZ01000001_gene2155 1.8e-219 769.2 Verrucomicrobiae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2ITHQ@203494,46U8T@74201,COG0557@1,COG0557@2 NA|NA|NA K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs JOKFNDED_04534 240016.ABIZ01000001_gene2568 4.2e-160 572.0 Verrucomicrobiae tsp 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 2IU0C@203494,46S88@74201,COG0793@1,COG0793@2 NA|NA|NA M tail specific protease JOKFNDED_04535 240016.ABIZ01000001_gene3449 1.2e-181 643.7 Verrucomicrobiae 3.6.4.13 ko:K17675 ko00000,ko01000,ko03029 Bacteria 2IV4K@203494,46SCW@74201,COG1204@1,COG1204@2 NA|NA|NA L helicase superfamily c-terminal domain JOKFNDED_04536 1396141.BATP01000059_gene2546 7.4e-16 90.5 Verrucomicrobiae Bacteria 2CIV9@1,2IUYN@203494,34A52@2,46W0H@74201 NA|NA|NA S Control of competence regulator ComK, YlbF/YmcA JOKFNDED_04539 497964.CfE428DRAFT_5946 1.2e-31 143.3 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation JOKFNDED_04542 497964.CfE428DRAFT_5669 2.9e-54 218.8 Verrucomicrobia CP_0643 Bacteria 46V2C@74201,COG4285@1,COG4285@2 NA|NA|NA S Biotin-protein ligase, N terminal JOKFNDED_04543 1396141.BATP01000026_gene1029 4.7e-122 444.5 Bacteria uxaB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.17,1.1.1.58 ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00631 R02555,R02703 RC00085 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c17480 Bacteria COG0246@1,COG0246@2 NA|NA|NA G mannitol metabolic process JOKFNDED_04544 1396418.BATQ01000155_gene2499 3.9e-24 117.9 Verrucomicrobiae moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 2IUXR@203494,46VYG@74201,COG0314@1,COG0314@2 NA|NA|NA H MoaE protein JOKFNDED_04545 1396418.BATQ01000155_gene2500 1.7e-207 728.8 Verrucomicrobiae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 2ITRA@203494,46SDE@74201,COG0362@1,COG0362@2 NA|NA|NA G 6-phosphogluconate dehydrogenase, C-terminal domain JOKFNDED_04547 240016.ABIZ01000001_gene370 1.1e-140 506.5 Verrucomicrobiae pilC ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2ITIH@203494,46S8P@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_04552 269798.CHU_0636 3.3e-34 151.0 Cytophagia cysD GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 47JCC@768503,4NEPD@976,COG0175@1,COG0175@2 NA|NA|NA EH TIGRFAM sulfate adenylyltransferase, small subunit JOKFNDED_04553 1121413.JMKT01000003_gene179 3.8e-23 114.4 Desulfovibrionales 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1N0QW@1224,2MFSC@213115,2X245@28221,42W70@68525,COG0399@1,COG0399@2 NA|NA|NA M 23S rRNA-intervening sequence protein JOKFNDED_04554 583355.Caka_0838 3.3e-191 674.5 Opitutae cysN GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7UH@414999,46UAI@74201,COG2895@1,COG2895@2 NA|NA|NA H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily JOKFNDED_04557 1396141.BATP01000004_gene5845 1.3e-133 483.0 Verrucomicrobiae potA 3.6.3.31 ko:K11072 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 Bacteria 2ITPH@203494,46SFH@74201,COG3842@1,COG3842@2 NA|NA|NA E ATPases associated with a variety of cellular activities JOKFNDED_04558 765952.PUV_07600 4.6e-72 278.1 Chlamydiae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 2JG99@204428,COG1176@1,COG1176@2 NA|NA|NA P ABC-type spermidine putrescine transport system, permease component I JOKFNDED_04559 765952.PUV_07590 5.2e-70 271.2 Chlamydiae potC ko:K11069,ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iHN637.CLJU_RS10670 Bacteria 2JFN9@204428,COG1177@1,COG1177@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component JOKFNDED_04560 765952.PUV_07580 2.6e-90 339.0 Chlamydiae potD ko:K11069,ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 2JGD6@204428,COG0687@1,COG0687@2 NA|NA|NA E Bacterial extracellular solute-binding protein JOKFNDED_04561 1403819.BATR01000044_gene1265 4.1e-114 417.9 Verrucomicrobiae rrp-2 ko:K02481 ko00000,ko02022 Bacteria 2ITIG@203494,46SFE@74201,COG2204@1,COG2204@2 NA|NA|NA T Bacterial regulatory protein, Fis family JOKFNDED_04565 880072.Desac_0077 8e-237 826.2 Deltaproteobacteria 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,2WINH@28221,42N9K@68525,COG0286@1,COG0286@2 NA|NA|NA V PFAM N-6 DNA methylase JOKFNDED_04567 880072.Desac_0075 5.3e-179 634.0 Syntrophobacterales 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,2MR4B@213462,2X2AD@28221,42M3B@68525,COG0286@1,COG0286@2,COG0732@1,COG0732@2 NA|NA|NA L HsdM N-terminal domain JOKFNDED_04568 452637.Oter_0915 1.7e-42 179.5 Verrucomicrobia ko:K09017 ko00000,ko03000 Bacteria 46WIH@74201,COG1309@1,COG1309@2 NA|NA|NA K PFAM regulatory protein TetR JOKFNDED_04569 1403819.BATR01000140_gene4912 3.1e-100 372.1 Bacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity JOKFNDED_04570 240016.ABIZ01000001_gene3426 6e-68 264.2 Bacteria hrtA ko:K02003,ko:K09810,ko:K09814 ko02010,map02010 M00255,M00257,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria COG1136@1,COG1136@2 NA|NA|NA V lipoprotein transporter activity JOKFNDED_04571 706587.Desti_2201 1.3e-72 280.0 Deltaproteobacteria ko:K01993 ko00000 Bacteria 1NBFC@1224,2WWV4@28221,437Y7@68525,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family JOKFNDED_04572 1396141.BATP01000030_gene3647 1.6e-11 77.0 Verrucomicrobiae ttg2C ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 2IUM4@203494,46T81@74201,COG1463@1,COG1463@2 NA|NA|NA Q MlaD protein JOKFNDED_04574 1396141.BATP01000060_gene4743 9.3e-61 240.4 Verrucomicrobiae coaX 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU5A@203494,46T0X@74201,COG1521@1,COG1521@2 NA|NA|NA K Type III pantothenate kinase JOKFNDED_04575 1396418.BATQ01000007_gene1424 3.9e-85 321.6 Verrucomicrobiae glcK 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITKM@203494,46T0E@74201,COG1940@1,COG1940@2 NA|NA|NA GK ROK family JOKFNDED_04577 234267.Acid_0334 1e-16 95.5 Acidobacteria 2.3.2.13 ko:K22452 ko00000,ko01000 Bacteria 3Y5BT@57723,COG1305@1,COG1305@2 NA|NA|NA E Domain of unknown function (DUF3488) JOKFNDED_04578 497964.CfE428DRAFT_2383 2.2e-29 135.6 Verrucomicrobia Bacteria 2F78F@1,33ZPQ@2,46VT2@74201 NA|NA|NA JOKFNDED_04579 1396141.BATP01000056_gene3169 1.1e-87 330.5 Verrucomicrobiae Bacteria 2IWNM@203494,46VB9@74201,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase JOKFNDED_04580 240016.ABIZ01000001_gene2868 8.7e-51 207.6 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_04581 497964.CfE428DRAFT_3535 1.6e-26 125.2 Verrucomicrobia yfjA Bacteria 46VM0@74201,COG4842@1,COG4842@2 NA|NA|NA S Proteins of 100 residues with WXG JOKFNDED_04582 240016.ABIZ01000001_gene2640 3.5e-21 108.2 Verrucomicrobiae Bacteria 2ET52@1,2IVXP@203494,33KP5@2,46VY7@74201 NA|NA|NA JOKFNDED_04583 1396141.BATP01000058_gene2012 2.6e-08 64.3 Verrucomicrobiae Bacteria 2DD5J@1,2IWBI@203494,2ZGMA@2,46WYE@74201 NA|NA|NA JOKFNDED_04584 1396141.BATP01000030_gene3610 7e-96 357.5 Verrucomicrobiae rsmC 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IVWQ@203494,46XH5@74201,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase small domain JOKFNDED_04585 1396418.BATQ01000014_gene4360 3.4e-199 703.4 Verrucomicrobia 4.2.2.23 ko:K15125,ko:K18195 ko05133,map05133 ko00000,ko00001,ko00536,ko01000 PL4 Bacteria 46UBW@74201,COG3210@1,COG3210@2,COG4625@1,COG4625@2 NA|NA|NA U Passenger-associated-transport-repeat JOKFNDED_04586 1403819.BATR01000104_gene3538 2.5e-87 328.9 Verrucomicrobiae Bacteria 2IUQ3@203494,46SN7@74201,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase JOKFNDED_04588 1123070.KB899251_gene656 3.9e-58 231.5 Verrucomicrobiae yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 Bacteria 2IU7Z@203494,46VWT@74201,COG1720@1,COG1720@2 NA|NA|NA S Uncharacterised protein family UPF0066 JOKFNDED_04589 1396141.BATP01000028_gene2363 3.3e-97 361.7 Verrucomicrobiae 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2IVC1@203494,46XBP@74201,COG0510@1,COG0510@2 NA|NA|NA M Phosphotransferase enzyme family JOKFNDED_04590 243231.GSU1251 1e-16 96.3 Desulfuromonadales 3.2.1.20 ko:K01187,ko:K16915 ko00052,ko00500,ko01100,ko02010,map00052,map00500,map01100,map02010 M00246 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko02000 GH31 Bacteria 1R504@1224,2WKUI@28221,42QHC@68525,43VN4@69541,COG1361@1,COG1361@2,COG2372@1,COG2372@2,COG4447@1,COG4447@2,COG5184@1,COG5184@2 NA|NA|NA DZ Regulator of chromosome condensation (RCC1) repeat JOKFNDED_04591 1403819.BATR01000044_gene1285 7.5e-268 930.6 Verrucomicrobiae lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 2IUA8@203494,46S6U@74201,COG1201@1,COG1201@2 NA|NA|NA L DEAD/H associated JOKFNDED_04592 158500.BV97_05376 2.6e-16 92.4 Sphingomonadales ko:K07487 ko00000 Bacteria 1R70H@1224,2K8WF@204457,2U4GT@28211,COG3039@1,COG3039@2 NA|NA|NA L Transposase or inactivated derivative JOKFNDED_04594 521674.Plim_0117 4.4e-187 661.0 Planctomycetes Bacteria 2IZUB@203682,COG2072@1,COG2072@2 NA|NA|NA P FAD dependent oxidoreductase JOKFNDED_04595 794903.OPIT5_07795 5.1e-54 218.4 Bacteria ko:K02529,ko:K03435,ko:K05499 ko00000,ko03000 Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process JOKFNDED_04596 886293.Sinac_4875 3e-31 142.5 Planctomycetes Bacteria 2IZ2H@203682,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase JOKFNDED_04597 1403819.BATR01000084_gene2441 1.1e-13 84.3 Verrucomicrobia Bacteria 2E19R@1,32WPZ@2,46VE3@74201 NA|NA|NA JOKFNDED_04598 756272.Plabr_4236 1.4e-38 166.0 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J3Y8@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_04599 1403819.BATR01000084_gene2440 1.2e-211 743.8 Verrucomicrobiae Bacteria 2IWNW@203494,46UH6@74201,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1587) JOKFNDED_04601 59374.Fisuc_0956 2.3e-10 72.0 Bacteria Bacteria COG1569@1,COG1569@2 NA|NA|NA S PIN domain JOKFNDED_04602 240016.ABIZ01000001_gene1319 7.2e-68 263.5 Verrucomicrobiae Bacteria 2IVAN@203494,46U6Q@74201,COG2960@1,COG2960@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_04603 243090.RB546 2.7e-90 338.2 Planctomycetes Bacteria 2IXXZ@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_04604 595460.RRSWK_04696 9e-58 230.3 Planctomycetes Bacteria 2IZ2V@203682,COG0745@1,COG0745@2 NA|NA|NA K COG0745 Response regulators consisting of a CheY-like receiver JOKFNDED_04605 497964.CfE428DRAFT_0913 5.5e-37 162.2 Bacteria Bacteria COG5002@1,COG5002@2 NA|NA|NA T protein histidine kinase activity JOKFNDED_04606 497964.CfE428DRAFT_0912 4.3e-44 184.9 Verrucomicrobia ko:K02456,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 46W1C@74201,COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif JOKFNDED_04607 228410.NE1580 1.7e-08 65.1 Nitrosomonadales ko:K07722 ko00000,ko03000 Bacteria 1ND0M@1224,2WC7R@28216,374ER@32003,COG0864@1,COG0864@2 NA|NA|NA K Ribbon-helix-helix protein, copG family JOKFNDED_04608 1396141.BATP01000035_gene4134 1.7e-105 389.0 Verrucomicrobiae hisF ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITUS@203494,46S6V@74201,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit JOKFNDED_04610 1403819.BATR01000055_gene1725 2e-94 352.4 Verrucomicrobiae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2ITUM@203494,46SQ4@74201,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain JOKFNDED_04611 35841.BT1A1_1977 3.6e-45 187.6 Bacillus msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,1ZFQG@1386,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase JOKFNDED_04612 1396418.BATQ01000113_gene4620 3.9e-97 361.3 Verrucomicrobiae MA20_16875 iECBD_1354.ECBD_3826,iECB_1328.ECB_04075,iECS88_1305.ECS88_4797 Bacteria 2IU73@203494,46TV1@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_04613 1396418.BATQ01000014_gene4349 4.1e-111 407.9 Verrucomicrobiae 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWGM@203494,46V0D@74201,COG0329@1,COG0329@2 NA|NA|NA EM Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) JOKFNDED_04614 240016.ABIZ01000001_gene2098 6.2e-34 150.6 Verrucomicrobiae folK 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940,ko:K17488 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R10348,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC02504,RC03131,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0041 Bacteria 2IUKW@203494,46T2Z@74201,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) JOKFNDED_04615 1403819.BATR01000100_gene3350 1.3e-86 326.2 Verrucomicrobiae dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215,ko:K03546 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0510,iLJ478.TM1520,iSbBS512_1146.SbBS512_E0035 Bacteria 2IU1I@203494,46SPR@74201,COG0289@1,COG0289@2 NA|NA|NA E Dihydrodipicolinate reductase, N-terminus JOKFNDED_04616 240016.ABIZ01000001_gene2100 3.3e-97 361.7 Verrucomicrobiae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITUK@203494,46SDY@74201,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthetase family JOKFNDED_04617 240016.ABIZ01000001_gene2101 1e-105 389.8 Verrucomicrobiae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2ITVJ@203494,46SKV@74201,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan JOKFNDED_04618 1396418.BATQ01000135_gene3639 6e-90 337.4 Verrucomicrobiae trpA GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_1467,iECP_1309.ECP_1308 Bacteria 2ITJI@203494,46SK1@74201,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate JOKFNDED_04619 1403819.BATR01000117_gene4029 3.5e-43 182.2 Verrucomicrobiae ccmG ko:K03671,ko:K12057 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko02044,ko03110 3.A.7.11.1 Bacteria 2IW4P@203494,46TGF@74201,COG0526@1,COG0526@2 NA|NA|NA CO Redoxin JOKFNDED_04622 575615.HMPREF0670_00665 2.3e-45 189.9 Bacteroidia clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2FR21@200643,4NWPV@976,COG0740@1,COG0740@2,COG3740@1,COG3740@2 NA|NA|NA OU Belongs to the peptidase S14 family JOKFNDED_04623 1396418.BATQ01000046_gene6167 1.3e-70 272.7 Verrucomicrobiae Bacteria 2IUK8@203494,46UDR@74201,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases JOKFNDED_04624 331113.SNE_A16110 3.9e-24 118.6 Bacteria Bacteria COG0639@1,COG0639@2 NA|NA|NA T phosphoprotein phosphatase activity JOKFNDED_04625 497964.CfE428DRAFT_5252 1.3e-10 72.8 Verrucomicrobia Bacteria 28VU8@1,2ZHVX@2,46WF7@74201 NA|NA|NA JOKFNDED_04627 1396141.BATP01000059_gene2535 1.3e-07 63.5 Verrucomicrobiae Bacteria 29ZN6@1,2IW5V@203494,30MNQ@2,46XM0@74201 NA|NA|NA JOKFNDED_04628 1396141.BATP01000059_gene2536 2.8e-49 202.6 Verrucomicrobiae ko:K02460 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IUG2@203494,46VZT@74201,COG3156@1,COG3156@2 NA|NA|NA U Type II secretion system (T2SS), protein K JOKFNDED_04629 1396418.BATQ01000177_gene2864 1e-24 121.3 Verrucomicrobiae Bacteria 293V7@1,2IW1J@203494,2ZRAE@2,46WWA@74201 NA|NA|NA JOKFNDED_04630 1403819.BATR01000010_gene361 4.7e-19 101.3 Verrucomicrobiae Bacteria 2BNE4@1,2IWF1@203494,32H1R@2,46XRD@74201 NA|NA|NA JOKFNDED_04632 1403819.BATR01000010_gene362 2.8e-106 393.3 Verrucomicrobiae gspD ko:K02453,ko:K03219 ko03070,ko05111,map03070,map05111 M00331,M00332,M00542 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.6.1,3.A.6.3 Bacteria 2IU06@203494,46UJ6@74201,COG1450@1,COG1450@2 NA|NA|NA NU Bacterial type II/III secretion system short domain JOKFNDED_04633 240016.ABIZ01000001_gene3729 1.7e-47 196.1 Verrucomicrobiae plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2IUG8@203494,46SYR@74201,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases JOKFNDED_04635 1396418.BATQ01000018_gene4135 3.3e-25 122.9 Verrucomicrobia ko:K03466,ko:K05567,ko:K07114 ko00000,ko02000,ko03036 1.A.13.2.2,1.A.13.2.3,2.A.63.1,2.A.63.2,3.A.12 Bacteria 46VD3@74201,COG5414@1,COG5414@2 NA|NA|NA K histone acetyltransferase binding JOKFNDED_04637 1519464.HY22_11920 2.9e-67 263.1 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_04638 497964.CfE428DRAFT_3335 1.9e-64 253.1 Bacteria 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family JOKFNDED_04640 1123070.KB899254_gene1274 7.2e-65 253.8 Verrucomicrobiae umuD2 3.4.21.88 ko:K01356,ko:K03503 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2IU8D@203494,46SU8@74201,COG1974@1,COG1974@2 NA|NA|NA KT LexA DNA binding domain JOKFNDED_04641 869213.JCM21142_52220 4.4e-30 138.7 Bacteroidetes 3.4.21.107 ko:K04771,ko:K07126 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 4NTPS@976,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain JOKFNDED_04642 240016.ABIZ01000001_gene4847 6.4e-46 191.4 Bacteria Bacteria COG4886@1,COG4886@2 NA|NA|NA S regulation of response to stimulus JOKFNDED_04643 497964.CfE428DRAFT_2532 1.3e-57 229.9 Bacteria moxG ko:K00406,ko:K16255 ko00190,ko00680,ko01100,ko01120,ko02020,map00190,map00680,map01100,map01120,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_04644 1403819.BATR01000135_gene4812 3.6e-107 394.8 Verrucomicrobia 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 46UU4@74201,COG0329@1,COG0329@2 NA|NA|NA EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate JOKFNDED_04645 756272.Plabr_4234 0.0 1247.6 Planctomycetes Bacteria 2IX4M@203682,COG4692@1,COG4692@2 NA|NA|NA G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella JOKFNDED_04648 1123242.JH636436_gene247 2.7e-141 508.4 Planctomycetes Bacteria 2J1QW@203682,COG4409@1,COG4409@2 NA|NA|NA M BNR repeat-like domain JOKFNDED_04649 756272.Plabr_4230 6.9e-42 177.6 Planctomycetes MA20_15070 Bacteria 2J0K9@203682,COG1802@1,COG1802@2 NA|NA|NA K COG1802 Transcriptional regulators JOKFNDED_04650 497964.CfE428DRAFT_3570 5.5e-37 160.6 Verrucomicrobia Bacteria 2F83K@1,340H0@2,46VYE@74201 NA|NA|NA S Domain of unknown function (DUF5069) JOKFNDED_04651 1128421.JAGA01000002_gene1917 5e-143 514.6 unclassified Bacteria glpD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2NP90@2323,COG0578@1,COG0578@2 NA|NA|NA C C-terminal domain of alpha-glycerophosphate oxidase JOKFNDED_04652 1403819.BATR01000051_gene1523 1.2e-20 105.9 Verrucomicrobiae Bacteria 29N5U@1,2IUXI@203494,3093R@2,46ZI4@74201 NA|NA|NA JOKFNDED_04654 1396141.BATP01000022_gene436 1.1e-39 169.9 Verrucomicrobiae pilC2 ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IV7F@203494,46YT3@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_04655 1068978.AMETH_0075 1.7e-10 72.0 Actinobacteria ko:K07001 ko00000 Bacteria 2I9XW@201174,COG1752@1,COG1752@2 NA|NA|NA S Patatin-like phospholipase JOKFNDED_04656 509635.N824_26535 1.3e-146 526.9 Sphingobacteriia Bacteria 1IUS0@117747,4NKGB@976,COG3590@1,COG3590@2 NA|NA|NA O peptidase JOKFNDED_04657 1089547.KB913013_gene3291 7.3e-67 261.5 Cytophagia Bacteria 47QYX@768503,4NN5Y@976,COG2333@1,COG2333@2 NA|NA|NA S competence protein COMEC JOKFNDED_04660 1396141.BATP01000001_gene5376 5.4e-09 67.8 Verrucomicrobiae Bacteria 2FDAI@1,2IVX3@203494,345CE@2,46WE8@74201 NA|NA|NA JOKFNDED_04663 765913.ThidrDRAFT_1088 5.7e-08 62.4 Chromatiales moaB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 R09726 RC00002 ko00000,ko00001,ko01000 Bacteria 1R9W2@1224,1S21E@1236,1WXCN@135613,COG0521@1,COG0521@2 NA|NA|NA H May be involved in the biosynthesis of molybdopterin JOKFNDED_04665 644076.SCH4B_2047 2.8e-31 142.9 Bacteria Bacteria 2EC1E@1,342WX@2 NA|NA|NA JOKFNDED_04666 1403819.BATR01000070_gene2110 5e-41 174.5 Verrucomicrobiae 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 2IUFY@203494,46VNJ@74201,COG0860@1,COG0860@2 NA|NA|NA M Ami_3 JOKFNDED_04667 1396418.BATQ01000030_gene5621 1.8e-95 356.7 Verrucomicrobiae nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2ITJV@203494,46S7Z@74201,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration JOKFNDED_04668 1121013.P873_12200 5.2e-15 87.8 Xanthomonadales Bacteria 1NKGS@1224,1T65R@1236,1X8HF@135614,2E37T@1,32Y7G@2 NA|NA|NA S Protein of unknown function (DUF2752) JOKFNDED_04669 879243.Poras_0441 3.3e-15 88.6 Porphyromonadaceae Bacteria 231X5@171551,2G2JT@200643,4PNK2@976,COG4640@1,COG4640@2 NA|NA|NA S Interferon-induced transmembrane protein JOKFNDED_04670 1403819.BATR01000118_gene4120 3e-28 131.7 Verrucomicrobiae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2IUS4@203494,46WBN@74201,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA JOKFNDED_04671 497964.CfE428DRAFT_6336 2.7e-121 442.6 Verrucomicrobia yqfF ko:K07037 ko00000 Bacteria 46S4P@74201,COG1480@1,COG1480@2 NA|NA|NA S 7TM receptor with intracellular HD hydrolase JOKFNDED_04672 1403819.BATR01000184_gene6380 1.3e-107 396.4 Verrucomicrobiae queA 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 2IU22@203494,46SDA@74201,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) JOKFNDED_04673 595460.RRSWK_03471 1.4e-116 426.4 Planctomycetes GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 4.2.1.129,5.4.99.17,5.5.1.16 ko:K06045,ko:K17811 ko00909,ko01110,map00909,map01110 R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 Bacteria 2J1Q5@203682,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase JOKFNDED_04674 756272.Plabr_3534 4.1e-42 179.5 Planctomycetes lprD ko:K02005 ko00000 Bacteria 2J3HT@203682,COG1566@1,COG1566@2 NA|NA|NA V PFAM secretion protein HlyD family protein JOKFNDED_04675 1396418.BATQ01000125_gene5093 1e-60 240.7 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_04677 1396418.BATQ01000017_gene4160 6.6e-34 153.7 Verrucomicrobiae oapA 2.7.11.1 ko:K02451,ko:K03086,ko:K07268,ko:K08884 M00331 ko00000,ko00002,ko01000,ko01001,ko02044,ko03021 9.B.42 Bacteria 2IW2X@203494,46VKK@74201,COG3266@1,COG3266@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane JOKFNDED_04678 1396141.BATP01000007_gene5552 6.9e-31 140.2 Verrucomicrobiae rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IUTW@203494,46T8H@74201,COG0799@1,COG0799@2 NA|NA|NA S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation JOKFNDED_04679 1396141.BATP01000007_gene5551 5.8e-108 397.9 Verrucomicrobiae cinA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 ko:K03742 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2ITHX@203494,46SRG@74201,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Competence-damaged protein JOKFNDED_04681 240016.ABIZ01000001_gene4631 2.9e-36 159.1 Verrucomicrobiae Bacteria 2IUKZ@203494,46SY5@74201,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family JOKFNDED_04682 1396141.BATP01000007_gene5667 1.8e-102 379.4 Verrucomicrobiae gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10 ko:K00600,ko:K00605 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R01221,R02300,R04125,R09099 RC00022,RC00069,RC00112,RC00183,RC01583,RC02834,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITVC@203494,46UPA@74201,COG0404@1,COG0404@2 NA|NA|NA E Aminomethyltransferase folate-binding domain JOKFNDED_04683 1304885.AUEY01000096_gene2839 2.6e-125 456.4 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_04684 240016.ABIZ01000001_gene4629 5.4e-33 147.1 Verrucomicrobiae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IUJ1@203494,46VKU@74201,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein JOKFNDED_04686 1403819.BATR01000183_gene6323 6.7e-10 71.2 Verrucomicrobiae Bacteria 2CK46@1,2IUZS@203494,337US@2,46X8B@74201 NA|NA|NA JOKFNDED_04687 1396418.BATQ01000044_gene6481 1.5e-12 79.0 Verrucomicrobiae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IV02@203494,46WWC@74201,COG0268@1,COG0268@2 NA|NA|NA J Ribosomal protein S20 JOKFNDED_04688 1396418.BATQ01000049_gene393 6.2e-50 204.5 Verrucomicrobiae ko:K19234,ko:K19236 ko01503,map01503 ko00000,ko00001,ko01002,ko01011 Bacteria 2IUGD@203494,46VQZ@74201,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain JOKFNDED_04689 1403819.BATR01000092_gene2802 1.7e-56 226.5 Verrucomicrobiae Bacteria 2F4CA@1,2IUA1@203494,33X2V@2,46VIX@74201 NA|NA|NA JOKFNDED_04691 497964.CfE428DRAFT_4159 7.1e-112 410.2 Verrucomicrobia trpB 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 46SHR@74201,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine JOKFNDED_04695 1396141.BATP01000047_gene3938 4.3e-68 265.0 Verrucomicrobiae pgdA GO:0005575,GO:0016020 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 2IU6W@203494,46UKH@74201,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase JOKFNDED_04696 1163409.UUA_13265 3.7e-07 62.8 Bacteria yxkC Bacteria 2DY9G@1,348S7@2 NA|NA|NA S Domain of unknown function (DUF4352) JOKFNDED_04698 1123070.KB899251_gene742 1.4e-62 246.5 Verrucomicrobiae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2IU7R@203494,46SSV@74201,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs JOKFNDED_04699 314256.OG2516_13089 6.8e-11 75.1 Bacteria rhaS 3.2.2.21 ko:K02854,ko:K02855,ko:K13529,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria COG2169@1,COG2169@2 NA|NA|NA K sequence-specific DNA binding JOKFNDED_04700 1123070.KB899248_gene84 5.7e-90 337.4 Verrucomicrobiae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IU1A@203494,46TGT@74201,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family JOKFNDED_04701 240016.ABIZ01000001_gene3117 2.5e-103 382.1 Verrucomicrobiae 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 Bacteria 2IU5T@203494,46UCI@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_04702 1403819.BATR01000130_gene4599 4.4e-51 208.4 Verrucomicrobiae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IUJR@203494,46V68@74201,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein JOKFNDED_04703 1396418.BATQ01000106_gene5307 4.8e-83 315.8 Verrucomicrobiae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IUBV@203494,46UZA@74201,COG3225@1,COG3225@2 NA|NA|NA N ABC-type uncharacterized transport system JOKFNDED_04704 1403819.BATR01000130_gene4597 1.8e-42 180.6 Verrucomicrobiae Bacteria 2DTXG@1,2IVTG@203494,33N3G@2,46WXU@74201 NA|NA|NA S Domain of unknown function (DUF4340) JOKFNDED_04705 521674.Plim_0119 9.4e-58 231.9 Planctomycetes Bacteria 2IWUM@203682,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JOKFNDED_04707 349741.Amuc_1236 2.6e-39 168.3 Verrucomicrobiae rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 2IUIQ@203494,46VXG@74201,COG1576@1,COG1576@2 NA|NA|NA J Predicted SPOUT methyltransferase JOKFNDED_04708 794903.OPIT5_27985 5.6e-72 277.7 Opitutae ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029,ko:K22132 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000,ko03016 Bacteria 3K7JI@414999,46THP@74201,COG1179@1,COG1179@2 NA|NA|NA H PFAM UBA THIF-type NAD FAD binding protein JOKFNDED_04709 243090.RB908 8.6e-19 102.1 Planctomycetes Bacteria 2J3SH@203682,COG3712@1,COG3712@2 NA|NA|NA PT iron ion homeostasis JOKFNDED_04710 314230.DSM3645_25086 1.9e-34 152.5 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J0H5@203682,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_04718 1396418.BATQ01000089_gene6023 2e-72 278.9 Verrucomicrobiae ko:K01066 ko00000,ko01000 Bacteria 2IVDK@203494,46U5Z@74201,COG0657@1,COG0657@2 NA|NA|NA I Protein of unknown function (DUF1460) JOKFNDED_04719 1123070.KB899258_gene1915 8.1e-59 234.2 Verrucomicrobiae Bacteria 2IUGE@203494,46V15@74201,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain JOKFNDED_04720 497964.CfE428DRAFT_1974 1.6e-221 775.8 Verrucomicrobia nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 46S9D@74201,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source JOKFNDED_04721 1403819.BATR01000164_gene5599 3.8e-105 388.3 Verrucomicrobiae pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 Bacteria 2IU2W@203494,46S5W@74201,COG0167@1,COG0167@2 NA|NA|NA F Dihydroorotate dehydrogenase JOKFNDED_04722 240016.ABIZ01000001_gene2063 6.2e-113 414.1 Verrucomicrobiae Bacteria 2IVBS@203494,46XBK@74201,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family JOKFNDED_04723 1403819.BATR01000137_gene4883 2e-141 509.2 Verrucomicrobiae algI ko:K19294 ko00000 Bacteria 2IV8E@203494,46TUI@74201,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family JOKFNDED_04724 1396418.BATQ01000085_gene1112 4.6e-54 219.2 Bacteria ko:K19295 ko00000 Bacteria 2C7PP@1,33K9Q@2 NA|NA|NA S SGNH hydrolase-like domain, acetyltransferase AlgX JOKFNDED_04725 243090.RB8423 1.4e-190 672.9 Planctomycetes ko:K01138 ko00000,ko01000 Bacteria 2IYFZ@203682,COG1413@1,COG1413@2,COG3119@1,COG3119@2 NA|NA|NA CP COG3119 Arylsulfatase A JOKFNDED_04726 1396418.BATQ01000001_gene1243 6.4e-71 275.0 Verrucomicrobiae fdhD ko:K02379 ko00000 Bacteria 2IUBY@203494,46SPA@74201,COG1526@1,COG1526@2 NA|NA|NA C FdhD/NarQ family JOKFNDED_04727 1173028.ANKO01000094_gene2627 1e-38 167.2 Oscillatoriales ydjX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1GDAR@1117,1HFDF@1150,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein JOKFNDED_04728 1396141.BATP01000016_gene2817 4.4e-12 78.2 Verrucomicrobiae Bacteria 2EGCD@1,2IWC7@203494,33A46@2,46Z2P@74201 NA|NA|NA S Domain of unknown function (DUF4190) JOKFNDED_04729 1403819.BATR01000002_gene17 3.6e-83 315.1 Verrucomicrobiae adoK GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2683 Bacteria 2IU19@203494,46U0Y@74201,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase JOKFNDED_04730 497964.CfE428DRAFT_1676 1.4e-49 203.0 Verrucomicrobia thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iJN678.thiE,iNJ661.Rv0414c Bacteria 46T6K@74201,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) JOKFNDED_04731 1123070.KB899267_gene2475 3e-14 85.1 Verrucomicrobiae exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 2IUYI@203494,46W26@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_04733 1238450.VIBNISOn1_600027 7e-37 160.6 Vibrionales lemA ko:K03744 ko00000 Bacteria 1MVH0@1224,1RP1N@1236,1XXK8@135623,COG1704@1,COG1704@2 NA|NA|NA S LemA family JOKFNDED_04734 1123070.KB899263_gene1741 9e-48 197.6 Verrucomicrobiae Bacteria 2IVKP@203494,46ZKS@74201,COG0457@1,COG0457@2 NA|NA|NA S Protein of unknown function (DUF3137) JOKFNDED_04735 349741.Amuc_0592 5.5e-79 301.2 Verrucomicrobiae thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iSFV_1184.SFV_0382,iYO844.BSU05900 Bacteria 2IU3R@203494,46SV7@74201,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 JOKFNDED_04736 1396141.BATP01000030_gene3729 9.3e-34 149.8 Verrucomicrobiae yjeE 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 2IUJT@203494,46T3C@74201,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE JOKFNDED_04737 240016.ABIZ01000001_gene5109 1.9e-22 112.8 Verrucomicrobiae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2IUPV@203494,46T3K@74201,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family JOKFNDED_04738 344747.PM8797T_15401 2.5e-174 619.4 Planctomycetes Bacteria 2IX64@203682,COG3064@1,COG3064@2 NA|NA|NA M Membrane JOKFNDED_04739 46234.ANA_C13529 1.3e-50 207.2 Nostocales Bacteria 1GCBA@1117,1HQPK@1161,COG4637@1,COG4637@2 NA|NA|NA S AAA ATPase domain JOKFNDED_04740 1254432.SCE1572_28780 7.1e-32 144.4 Myxococcales Bacteria 1QA1Q@1224,2E1W1@1,2X8ZZ@28221,2Z17W@29,32X59@2,434RY@68525 NA|NA|NA JOKFNDED_04741 344747.PM8797T_15396 1.7e-252 879.0 Planctomycetes ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2IXPF@203682,COG5492@1,COG5492@2 NA|NA|NA N Protein of unknown function (DUF1549) JOKFNDED_04742 497964.CfE428DRAFT_2799 2.6e-189 668.3 Verrucomicrobia Bacteria 46TS2@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04743 1403819.BATR01000022_gene764 2.9e-13 82.4 Verrucomicrobia Bacteria 298EK@1,2ZVJT@2,46WW2@74201 NA|NA|NA JOKFNDED_04744 1396141.BATP01000040_gene2122 1.6e-47 196.1 Verrucomicrobiae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IUHG@203494,46SZF@74201,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB JOKFNDED_04745 497964.CfE428DRAFT_4568 4.5e-130 471.5 Verrucomicrobia Bacteria 28MGX@1,2ZATZ@2,46TJV@74201 NA|NA|NA JOKFNDED_04747 1403819.BATR01000020_gene646 1.4e-100 372.9 Verrucomicrobiae xerC ko:K04763 ko00000,ko03036 Bacteria 2ITH5@203494,46SSD@74201,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain JOKFNDED_04749 1123070.KB899248_gene211 6e-31 140.6 Verrucomicrobiae fur ko:K03466,ko:K03711 ko00000,ko03000,ko03036 3.A.12 Bacteria 2IUDH@203494,46YG1@74201,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family JOKFNDED_04750 583355.Caka_0623 2.7e-167 595.5 Opitutae cysJ 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7H9@414999,46UED@74201,COG0369@1,COG0369@2 NA|NA|NA C Oxidoreductase NAD-binding domain JOKFNDED_04751 1123070.KB899249_gene392 1.3e-60 239.2 Verrucomicrobiae cysI GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0020037,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0097159,GO:1901363 1.7.7.1,1.8.1.2,1.8.7.1 ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_3037,iECH74115_1262.ECH74115_4017,iECIAI1_1343.ECIAI1_2867,iECNA114_1301.ECNA114_2794,iECO103_1326.ECO103_3307,iECSE_1348.ECSE_3019,iECSF_1327.ECSF_2552,iECSP_1301.ECSP_3712,iECUMN_1333.ECUMN_3091,iECW_1372.ECW_m2971,iECs_1301.ECs3618,iEKO11_1354.EKO11_1005,iEcE24377_1341.EcE24377A_3065,iSFV_1184.SFV_2742,iSbBS512_1146.SbBS512_E3112,iWFL_1372.ECW_m2971,iZ_1308.Z4073 Bacteria 2ITJ8@203494,46U85@74201,COG0155@1,COG0155@2 NA|NA|NA P Nitrite and sulphite reductase 4Fe-4S domain JOKFNDED_04752 240016.ABIZ01000001_gene272 2.1e-14 85.1 Verrucomicrobia Bacteria 46SZK@74201,COG0859@1,COG0859@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) JOKFNDED_04753 1123070.KB899254_gene1231 1.9e-66 259.2 Verrucomicrobiae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2IU7S@203494,46T3X@74201,COG0571@1,COG0571@2 NA|NA|NA K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism JOKFNDED_04755 1403819.BATR01000031_gene1027 1.4e-32 146.4 Verrucomicrobiae Bacteria 2IUK2@203494,46T5M@74201,COG4293@1,COG4293@2 NA|NA|NA S Domain of unknown function (DUF1802) JOKFNDED_04756 1396418.BATQ01000070_gene738 1.5e-40 173.3 Verrucomicrobiae CP_0228 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUE8@203494,46T10@74201,COG1579@1,COG1579@2 NA|NA|NA S C4-type zinc ribbon domain JOKFNDED_04758 99598.Cal7507_1165 5.2e-76 292.7 Nostocales Bacteria 1G135@1117,1HIJM@1161,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA S SPTR Tetratricopeptide TPR_2 repeat protein JOKFNDED_04760 1396418.BATQ01000054_gene28 2.8e-30 139.0 Bacteria 2.7.13.3 ko:K07636,ko:K11527,ko:K17292,ko:K19616 ko02020,map02020 M00434,M00771 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko04147,ko04812 Bacteria COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase JOKFNDED_04761 1121456.ATVA01000018_gene275 1.6e-101 376.7 Desulfovibrionales ko:K02481,ko:K07712 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2M8VA@213115,2WIT0@28221,42M03@68525,COG2204@1,COG2204@2 NA|NA|NA T Two component, sigma54 specific, transcriptional regulator, Fis family JOKFNDED_04762 1396141.BATP01000032_gene4372 4.1e-43 180.6 Verrucomicrobiae ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 2IUGB@203494,46VXS@74201,COG0347@1,COG0347@2 NA|NA|NA E Nitrogen regulatory protein P-II JOKFNDED_04763 349741.Amuc_2115 4.7e-73 280.8 Verrucomicrobiae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 2ITV1@203494,46S70@74201,COG0172@1,COG0172@2 NA|NA|NA J Seryl-tRNA synthetase N-terminal domain JOKFNDED_04767 1396418.BATQ01000137_gene3876 1.2e-76 293.1 Verrucomicrobiae mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 R11090 RC00002,RC00203 ko00000,ko01000 Bacteria 2IU6R@203494,46SMN@74201,COG3880@1,COG3880@2 NA|NA|NA C Cytochrome c7 and related cytochrome c JOKFNDED_04769 497964.CfE428DRAFT_5050 3.7e-16 92.0 Verrucomicrobia Bacteria 2C6Y7@1,341SH@2,46VND@74201 NA|NA|NA S Prokaryotic N-terminal methylation motif JOKFNDED_04770 240016.ABIZ01000001_gene238 1.5e-48 200.3 Verrucomicrobia Bacteria 2EXY4@1,33R78@2,46TZ1@74201 NA|NA|NA JOKFNDED_04771 1396418.BATQ01000012_gene4388 1.2e-07 63.5 Verrucomicrobia Bacteria 2DY12@1,347IY@2,46W7C@74201 NA|NA|NA JOKFNDED_04772 1396418.BATQ01000182_gene884 7.4e-164 585.5 Verrucomicrobia Bacteria 2EWTT@1,33Q5C@2,46UXR@74201 NA|NA|NA JOKFNDED_04773 240016.ABIZ01000001_gene3731 9.8e-15 85.5 Verrucomicrobiae aroA 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITVM@203494,46SFD@74201,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate JOKFNDED_04774 709986.Deima_0518 4.1e-138 498.0 Deinococcus-Thermus 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 1WK2R@1297,COG1092@1,COG1092@2 NA|NA|NA J PFAM S-adenosylmethionine-dependent methyltransferase JOKFNDED_04775 502025.Hoch_1254 1.2e-18 100.9 Myxococcales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1PSEB@1224,2X4F0@28221,2YYWA@29,4340G@68525,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase and related enzymes JOKFNDED_04776 349161.Dred_2357 1.4e-68 267.3 Clostridia Bacteria 1V17S@1239,24GRG@186801,COG5492@1,COG5492@2 NA|NA|NA N S-layer domain-containing protein JOKFNDED_04778 1137799.GZ78_08415 2.2e-94 352.1 Gammaproteobacteria queH 1.17.99.6,3.1.26.4 ko:K03470,ko:K09765 ko03030,map03030 ko00000,ko00001,ko01000,ko03016,ko03032 Bacteria 1MUG5@1224,1RPEH@1236,COG1636@1,COG1636@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) JOKFNDED_04779 1396141.BATP01000006_gene5477 1.6e-202 713.0 Verrucomicrobiae Bacteria 2IV8Z@203494,46TDA@74201,COG1680@1,COG1680@2,COG3876@1,COG3876@2 NA|NA|NA V Beta-lactamase JOKFNDED_04781 1396418.BATQ01000039_gene6499 2.2e-07 62.8 Bacteria Bacteria 2DMJ5@1,32RXW@2 NA|NA|NA JOKFNDED_04782 1123070.KB899268_gene2422 3.3e-79 301.2 Verrucomicrobiae trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2IU46@203494,46SN1@74201,COG0512@1,COG0512@2 NA|NA|NA EH Peptidase C26 JOKFNDED_04783 1123070.KB899268_gene2418 2.4e-113 415.6 Bacteria Bacteria COG3828@1,COG3828@2 NA|NA|NA N Trehalose utilisation JOKFNDED_04784 1403819.BATR01000049_gene1419 1.8e-40 173.3 Verrucomicrobiae ko:K09973 ko00000 Bacteria 2IWHA@203494,46VTS@74201,COG3735@1,COG3735@2 NA|NA|NA S TraB family JOKFNDED_04785 452637.Oter_0113 3.4e-15 87.4 Opitutae grxC ko:K03676,ko:K06191,ko:K07390 ko00000,ko03029,ko03110 Bacteria 3K8HC@414999,46TC3@74201,COG0695@1,COG0695@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain JOKFNDED_04786 1396418.BATQ01000045_gene6078 2e-13 84.7 Verrucomicrobiae CP_0766 2.7.13.3 ko:K07777,ko:K21449 ko02020,map02020 M00478 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 1.B.40.2 Bacteria 2IUR7@203494,46T1H@74201,COG0457@1,COG0457@2,COG1196@1,COG1196@2 NA|NA|NA D Tetratricopeptide repeat JOKFNDED_04787 1396141.BATP01000060_gene4715 1e-162 580.5 Verrucomicrobiae Bacteria 2ITIC@203494,46YZ0@74201,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain JOKFNDED_04788 497964.CfE428DRAFT_0190 5.6e-22 112.1 Verrucomicrobia sprB 3.4.21.80,3.4.21.81,3.4.21.82 ko:K18544,ko:K18545,ko:K18546,ko:K18547,ko:K18548 ko00000,ko01000,ko01002 Bacteria 46WAW@74201,COG0265@1,COG0265@2 NA|NA|NA O PDZ DHR GLGF domain protein JOKFNDED_04790 1403819.BATR01000031_gene1026 2.8e-85 322.4 Verrucomicrobiae alr 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 2IU27@203494,46SM1@74201,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids JOKFNDED_04791 1396141.BATP01000040_gene2142 6e-45 187.2 Verrucomicrobiae Bacteria 2F7MR@1,2IVRG@203494,30HKW@2,46XFA@74201 NA|NA|NA JOKFNDED_04792 756272.Plabr_4351 7.8e-48 197.6 Planctomycetes ko:K09992 ko00000 Bacteria 2IWYB@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type JOKFNDED_04793 240016.ABIZ01000001_gene2767 1.7e-31 143.3 Verrucomicrobia ko:K02854 ko00000,ko03000 Bacteria 46VWH@74201,COG1917@1,COG1917@2,COG2207@1,COG2207@2 NA|NA|NA K Cupin domain JOKFNDED_04797 497964.CfE428DRAFT_6342 1.3e-81 312.0 Verrucomicrobia Bacteria 46TMJ@74201,COG3064@1,COG3064@2 NA|NA|NA M Peptidase M60-like family JOKFNDED_04798 344747.PM8797T_02664 0.0 1124.8 Planctomycetes Bacteria 2IXND@203682,COG3748@1,COG3748@2 NA|NA|NA S Protein of unknown function (DUF1585) JOKFNDED_04799 756272.Plabr_3081 3.8e-198 697.6 Planctomycetes Bacteria 28KER@1,2J52W@203682,2ZA0Z@2 NA|NA|NA S Protein of unknown function (DUF1552) JOKFNDED_04800 313628.LNTAR_07074 2e-117 429.5 Bacteria atsA 3.1.6.4 ko:K01132 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00077,M00079 R07806 ko00000,ko00001,ko00002,ko01000 Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_04801 177437.HRM2_48570 2.5e-85 322.4 Deltaproteobacteria Bacteria 1Q98F@1224,2WQUY@28221,42U7M@68525,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase JOKFNDED_04802 497964.CfE428DRAFT_3578 3.3e-141 508.4 Bacteria Bacteria COG3119@1,COG3119@2 NA|NA|NA P arylsulfatase activity JOKFNDED_04803 240016.ABIZ01000001_gene5469 5.3e-222 776.9 Verrucomicrobiae Bacteria 2ITHU@203494,46TYJ@74201,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_04804 1123508.JH636439_gene1234 5.5e-188 664.5 Planctomycetes Bacteria 2IX0M@203682,COG4654@1,COG4654@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04805 1313301.AUGC01000001_gene1690 3.3e-101 375.2 Bacteroidetes pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 4NG40@976,COG0006@1,COG0006@2 NA|NA|NA E Aminopeptidase JOKFNDED_04807 1156937.MFUM_250004 9.1e-63 247.7 unclassified Verrucomicrobia ampC Bacteria 37GHB@326457,46UDJ@74201,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase JOKFNDED_04809 1210884.HG799464_gene10387 2.8e-69 269.6 Planctomycetes Bacteria 2IXS5@203682,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase JOKFNDED_04810 1123242.JH636434_gene4794 2.2e-118 432.2 Planctomycetes Bacteria 2IXJ6@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04812 290315.Clim_0586 9.8e-23 113.2 Bacteria Z012_06325 Bacteria COG1403@1,COG1403@2 NA|NA|NA V endonuclease activity JOKFNDED_04813 1111728.ATYS01000009_gene519 1.3e-38 166.8 Gammaproteobacteria VY92_09500 Bacteria 1RCAE@1224,1S2KJ@1236,2DMN1@1,32SKS@2 NA|NA|NA S Carbohydrate family 9 binding domain-like JOKFNDED_04814 1396141.BATP01000020_gene57 1.4e-39 169.5 Verrucomicrobiae Bacteria 2IUT6@203494,46WE1@74201,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase JOKFNDED_04815 1301098.PKB_3982 6.3e-94 350.9 Gammaproteobacteria ilvA_1 4.3.1.17,4.3.1.19 ko:K01754,ko:K17989 ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00590,R00996 RC00331,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVWJ@1224,1RPSE@1236,COG1171@1,COG1171@2 NA|NA|NA E Threonine dehydratase JOKFNDED_04816 1403819.BATR01000092_gene2710 1.8e-18 99.8 Verrucomicrobiae Bacteria 2ITMY@203494,46U9B@74201,COG0457@1,COG0457@2 NA|NA|NA S Peptidase MA superfamily JOKFNDED_04817 1396141.BATP01000039_gene1293 1e-16 94.0 Verrucomicrobiae ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IWQT@203494,46Z9V@74201,COG1450@1,COG1450@2 NA|NA|NA NU Type ii and iii secretion system protein JOKFNDED_04819 240016.ABIZ01000001_gene5658 3.8e-172 611.3 Verrucomicrobiae rrp-2 ko:K02481 ko00000,ko02022 Bacteria 2ITIG@203494,46SFE@74201,COG2204@1,COG2204@2 NA|NA|NA T Bacterial regulatory protein, Fis family JOKFNDED_04820 240016.ABIZ01000001_gene5818 1.4e-38 166.0 Verrucomicrobiae Bacteria 2ITPC@203494,46Z4V@74201,COG3852@1,COG3852@2 NA|NA|NA T PAS domain JOKFNDED_04822 1396418.BATQ01000067_gene1743 8.9e-55 220.3 Verrucomicrobiae yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 2IUDE@203494,46STZ@74201,COG1496@1,COG1496@2 NA|NA|NA S Multi-copper polyphenol oxidoreductase laccase JOKFNDED_04824 1403819.BATR01000159_gene5244 2.3e-166 592.8 Verrucomicrobiae pbpC 2.4.1.129 ko:K05367 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2IV2J@203494,46TMS@74201,COG4953@1,COG4953@2 NA|NA|NA M Transglycosylase JOKFNDED_04825 1403819.BATR01000158_gene5243 1.5e-209 736.9 Verrucomicrobiae ko:K06894 ko00000 Bacteria 2IV8F@203494,46U44@74201,COG2373@1,COG2373@2 NA|NA|NA S Alpha-2-macroglobulin MG1 domain JOKFNDED_04826 1396418.BATQ01000171_gene2917 2.7e-131 474.9 Verrucomicrobiae metF 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITT5@203494,46UW6@74201,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase JOKFNDED_04828 314230.DSM3645_21027 7.4e-151 540.4 Planctomycetes Bacteria 2IYB2@203682,COG2327@1,COG2327@2 NA|NA|NA S Polysaccharide pyruvyl transferase JOKFNDED_04831 1396141.BATP01000022_gene415 3.1e-40 171.4 Verrucomicrobiae purB 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITG6@203494,46UUE@74201,COG0015@1,COG0015@2 NA|NA|NA F Adenylosuccinate lyase C-terminus JOKFNDED_04832 1396418.BATQ01000018_gene4121 1.5e-170 605.9 Verrucomicrobiae dapE 3.5.1.16,3.5.1.18 ko:K01436,ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2ITIW@203494,46UH8@74201,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain JOKFNDED_04833 2903.EOD35507 2.2e-115 422.5 Eukaryota GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19,2.7.1.160 ko:K00800,ko:K10669 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000,ko03016 Eukaryota COG0169@1,KOG0692@2759 NA|NA|NA E shikimate 3-dehydrogenase (NADP+) activity JOKFNDED_04834 1396141.BATP01000057_gene2975 4.5e-84 318.2 Verrucomicrobiae cbpA ko:K05516 ko00000,ko03036,ko03110 Bacteria 2IV3Z@203494,46S6P@74201,COG0484@1,COG0484@2 NA|NA|NA O DnaJ molecular chaperone homology domain JOKFNDED_04835 1123242.JH636435_gene1197 9.9e-258 896.0 Planctomycetes Bacteria 2IXWN@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_04836 1414720.CBYM010000013_gene2853 5.1e-20 104.8 Clostridiaceae Bacteria 1VN48@1239,25G74@186801,36K9P@31979,COG4640@1,COG4640@2 NA|NA|NA S YARHG JOKFNDED_04837 1403819.BATR01000137_gene4852 1.1e-88 333.6 Verrucomicrobiae pilC ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IU50@203494,46X1U@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_04838 240016.ABIZ01000001_gene3343 5.6e-26 124.0 Verrucomicrobiae gspG_1 ko:K02246,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IURN@203494,46W6A@74201,COG2165@1,COG2165@2 NA|NA|NA NU Type II secretion system (T2SS), protein G JOKFNDED_04841 240016.ABIZ01000001_gene3346 5.7e-29 135.2 Verrucomicrobiae Bacteria 29ZN6@1,2IW5V@203494,30MNQ@2,46XM0@74201 NA|NA|NA JOKFNDED_04842 1403819.BATR01000137_gene4857 2.9e-43 182.6 Verrucomicrobiae ko:K02460 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IUG2@203494,46VZT@74201,COG3156@1,COG3156@2 NA|NA|NA U Type II secretion system (T2SS), protein K JOKFNDED_04843 1403819.BATR01000066_gene1981 3.8e-77 294.7 Verrucomicrobiae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2ITZV@203494,46SS0@74201,COG0336@1,COG0336@2 NA|NA|NA J tRNA (Guanine-1)-methyltransferase JOKFNDED_04846 1396141.BATP01000027_gene1121 9.2e-09 67.8 Bacteria 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria COG0265@1,COG0265@2 NA|NA|NA O serine-type endopeptidase activity JOKFNDED_04847 1396141.BATP01000021_gene156 3.6e-158 564.7 Verrucomicrobiae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2ITRZ@203494,46S6Q@74201,COG0766@1,COG0766@2 NA|NA|NA M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) JOKFNDED_04848 1396141.BATP01000021_gene155 1.3e-66 260.0 Verrucomicrobiae prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2IU5P@203494,46SZE@74201,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif JOKFNDED_04849 706587.Desti_4341 6.4e-68 265.0 Proteobacteria ko:K14274 ko00040,map00040 R02427 RC00713 ko00000,ko00001,ko01000 Bacteria 1NIN4@1224,COG3386@1,COG3386@2 NA|NA|NA G Major royal jelly protein JOKFNDED_04850 1396141.BATP01000023_gene594 1.5e-157 563.1 Verrucomicrobiae ptsI 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 Bacteria 2ITIJ@203494,46TX4@74201,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) JOKFNDED_04851 1396418.BATQ01000123_gene4929 1e-22 112.5 Verrucomicrobiae ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 2IUM2@203494,46T6C@74201,COG1925@1,COG1925@2 NA|NA|NA G PTS HPr component phosphorylation site JOKFNDED_04852 240016.ABIZ01000001_gene2434 5e-99 367.9 Verrucomicrobiae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 2ITXV@203494,46S64@74201,COG1493@1,COG1493@2 NA|NA|NA T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) JOKFNDED_04854 1286632.P278_01290 6.7e-30 137.5 Flavobacteriia sigX ko:K03088 ko00000,ko03021 Bacteria 1HY4K@117743,4NHNI@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily JOKFNDED_04855 240016.ABIZ01000001_gene195 2.7e-33 148.7 Verrucomicrobiae Bacteria 2IW9S@203494,46WP2@74201,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family JOKFNDED_04856 1396418.BATQ01000168_gene1790 1.8e-87 330.1 Bacteria 1.1.2.6 ko:K05889,ko:K17713 R03136 ko00000,ko01000,ko02000 1.B.33.1 Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_04857 314230.DSM3645_13770 1.4e-107 396.7 Planctomycetes Bacteria 2IXZX@203682,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 JOKFNDED_04858 1123242.JH636434_gene5197 2.1e-111 409.5 Planctomycetes Bacteria 2J27K@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04859 335541.Swol_0795 2.8e-20 104.0 Clostridia Bacteria 1VJN4@1239,24TCC@186801,COG1598@1,COG1598@2 NA|NA|NA C PFAM Uncharacterised protein family UPF0150 JOKFNDED_04860 330214.NIDE2935 3.8e-24 117.1 Bacteria Bacteria COG1724@1,COG1724@2 NA|NA|NA N mRNA binding JOKFNDED_04861 497964.CfE428DRAFT_0984 3.4e-91 342.0 Bacteria Bacteria COG1680@1,COG1680@2 NA|NA|NA V peptidase activity JOKFNDED_04862 243090.RB11468 4.5e-72 277.7 Bacteria Bacteria 2DB7P@1,2Z7MR@2 NA|NA|NA JOKFNDED_04863 595460.RRSWK_06678 1.7e-118 433.3 Planctomycetes lppC GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06910 ko00000 Bacteria 2J1MM@203682,COG1881@1,COG1881@2 NA|NA|NA G Phosphatidylethanolamine-binding protein JOKFNDED_04864 1403819.BATR01000181_gene6166 6.9e-45 187.6 Verrucomicrobiae aspA 3.1.21.3,3.6.1.13 ko:K01153,ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko02048 Bacteria 2IW2U@203494,46SST@74201,COG0494@1,COG0494@2,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_04865 382464.ABSI01000007_gene4118 2.3e-71 275.4 Verrucomicrobiae Bacteria 2IUEX@203494,46TFB@74201,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_04866 63737.Npun_R5315 3.8e-74 285.8 Nostocales 2.7.13.3 ko:K07636,ko:K07645 ko02020,ko02024,map02020,map02024 M00434,M00453 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1GQDS@1117,1HME7@1161,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JOKFNDED_04867 521674.Plim_1879 7.1e-154 551.6 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_04868 1403819.BATR01000163_gene5503 3.3e-74 285.0 Verrucomicrobiae Bacteria 2IVPP@203494,46STY@74201,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein JOKFNDED_04869 756272.Plabr_0402 1.8e-251 875.5 Planctomycetes Bacteria 2J4ZP@203682,COG1053@1,COG1053@2 NA|NA|NA C FAD dependent oxidoreductase JOKFNDED_04870 1122176.KB903598_gene4712 3e-70 273.5 Bacteria Bacteria COG2866@1,COG2866@2 NA|NA|NA E metallocarboxypeptidase activity JOKFNDED_04871 1280698.AUJS01000006_gene2837 1.7e-36 160.2 Dorea glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,248U9@186801,27UW1@189330,COG1940@1,COG1940@2 NA|NA|NA GK ROK family JOKFNDED_04873 1396141.BATP01000003_gene5208 3.4e-53 214.9 Verrucomicrobiae ppiA 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2IVTW@203494,46Z1N@74201,COG0652@1,COG0652@2 NA|NA|NA O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD JOKFNDED_04874 7425.NV10155-PB 1.8e-71 275.4 Hymenoptera 5.2.1.8 ko:K09565 ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145 ko00000,ko00001,ko01000,ko03110 Arthropoda 38FFS@33154,3B9YC@33208,3D1XY@33213,3SHCR@50557,41XHD@6656,46E5H@7399,COG0652@1,KOG0865@2759 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides JOKFNDED_04875 1123508.JH636444_gene5358 1.8e-164 585.9 Bacteria pys Bacteria COG1233@1,COG1233@2 NA|NA|NA Q all-trans-retinol 13,14-reductase activity JOKFNDED_04876 497964.CfE428DRAFT_0209 1.3e-18 100.5 Verrucomicrobia ydhO 3.4.14.13 ko:K20742,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 46SVG@74201,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family JOKFNDED_04877 240016.ABIZ01000001_gene4017 1.3e-110 406.4 Verrucomicrobiae Bacteria 2IVYR@203494,46SNR@74201,COG1609@1,COG1609@2 NA|NA|NA K Bacterial regulatory proteins, lacI family JOKFNDED_04878 1381751.JAJB01000023_gene1767 4.7e-10 72.4 Brevibacteriaceae yuxL 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria 2GMMM@201174,4F921@85019,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Prolyl oligopeptidase family JOKFNDED_04879 595460.RRSWK_05390 1.5e-11 75.9 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity JOKFNDED_04881 240016.ABIZ01000001_gene326 2.9e-146 525.4 Verrucomicrobiae ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299,ko:K03281 ko00000,ko01000,ko01002 2.A.49 Bacteria 2IU0U@203494,46TJB@74201,COG2317@1,COG2317@2 NA|NA|NA E Carboxypeptidase Taq (M32) metallopeptidase JOKFNDED_04882 452637.Oter_3570 4.1e-14 85.5 Verrucomicrobia 2.7.11.1 ko:K01173,ko:K14949 ko04210,ko05152,map04210,map05152 ko00000,ko00001,ko01000,ko01001,ko03029 Bacteria 46W40@74201,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain JOKFNDED_04883 1123070.KB899249_gene355 4.6e-74 284.3 Verrucomicrobiae rpsD GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2ITP0@203494,46SNI@74201,COG0522@1,COG0522@2 NA|NA|NA J Ribosomal protein S4/S9 N-terminal domain JOKFNDED_04884 1396418.BATQ01000056_gene187 1.6e-54 219.2 Verrucomicrobiae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IU6B@203494,46STW@74201,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome JOKFNDED_04885 1396418.BATQ01000056_gene186 1.4e-41 175.6 Verrucomicrobiae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUGG@203494,46VYP@74201,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits JOKFNDED_04886 1396141.BATP01000039_gene1420 8.7e-79 300.4 Verrucomicrobiae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2ITSS@203494,46SK6@74201,COG0024@1,COG0024@2 NA|NA|NA J Metallopeptidase family M24 JOKFNDED_04887 497964.CfE428DRAFT_0505 5.9e-82 310.8 Verrucomicrobia secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 46S86@74201,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently JOKFNDED_04889 502025.Hoch_2669 5.8e-31 141.7 Deltaproteobacteria Bacteria 1NN79@1224,2WVIB@28221,42ZVH@68525,COG5653@1,COG5653@2 NA|NA|NA M Acetyltransferase (GNAT) domain JOKFNDED_04890 290397.Adeh_0390 5.6e-20 105.5 Myxococcales srsC Bacteria 1N3JT@1224,2WVDD@28221,2YU0R@29,42S0W@68525,COG0644@1,COG0644@2 NA|NA|NA C FAD binding domain JOKFNDED_04894 395964.KE386496_gene542 6.2e-11 75.5 Beijerinckiaceae ko:K07052 ko00000 Bacteria 1REZN@1224,2U7J7@28211,3NB41@45404,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity JOKFNDED_04895 240016.ABIZ01000001_gene4801 1.5e-115 423.3 Verrucomicrobia Bacteria 46TSY@74201,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_04897 1303518.CCALI_01467 1.8e-54 219.5 Bacteria exsH 3.2.1.178,3.2.1.18,3.2.1.52 ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 M00079 R00022,R04018,R06004,R11316 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 GH16,GH20,GH33 Bacteria COG2273@1,COG2273@2 NA|NA|NA G xyloglucan:xyloglucosyl transferase activity JOKFNDED_04898 1396418.BATQ01000056_gene183 3e-34 152.5 Verrucomicrobiae Bacteria 2IUH2@203494,46ZJ8@74201,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold JOKFNDED_04899 1123070.KB899264_gene1809 2.7e-33 149.4 Verrucomicrobiae Bacteria 2B13X@1,2IUFM@203494,31THQ@2,46X3Y@74201 NA|NA|NA JOKFNDED_04900 497964.CfE428DRAFT_0066 3.4e-39 170.2 Verrucomicrobia 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 46TTW@74201,COG0515@1,COG0515@2,COG1262@1,COG1262@2 NA|NA|NA KLT Sulfatase-modifying factor enzyme 1 JOKFNDED_04901 1396141.BATP01000034_gene4155 9.3e-258 896.0 Verrucomicrobiae rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 Bacteria 2ITUF@203494,46SFY@74201,COG0539@1,COG0539@2 NA|NA|NA J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence JOKFNDED_04902 661478.OP10G_2640 1.5e-98 367.9 Bacteria Bacteria COG0642@1,COG2202@1,COG2202@2,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_04903 240016.ABIZ01000001_gene1337 3.7e-130 471.5 Verrucomicrobiae yhaZ Bacteria 2IVNE@203494,46U62@74201,COG4335@1,COG4335@2 NA|NA|NA L DNA alkylation repair JOKFNDED_04904 1096546.WYO_3214 4.9e-23 114.4 Methylobacteriaceae Bacteria 1JXVD@119045,1PVSD@1224,2V1ZP@28211,COG2405@1,COG2405@2 NA|NA|NA S Domain of unknown function (DUF3368) JOKFNDED_04906 530564.Psta_3475 0.0 1216.4 Planctomycetes ko:K09992 ko00000 Bacteria 2IWYB@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type JOKFNDED_04909 595460.RRSWK_03534 2.5e-193 681.8 Planctomycetes ko:K01138 ko00000,ko01000 Bacteria 2IXUN@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_04910 497964.CfE428DRAFT_0119 4e-17 95.5 Bacteria Bacteria COG1434@1,COG1434@2 NA|NA|NA S Gram-negative-bacterium-type cell wall biogenesis JOKFNDED_04911 240016.ABIZ01000001_gene3904 4.2e-26 124.8 Verrucomicrobia Bacteria 2DSGX@1,33G2Z@2,46W42@74201 NA|NA|NA JOKFNDED_04912 497964.CfE428DRAFT_2159 5.2e-82 311.2 Verrucomicrobia VVA1234 Bacteria 46SCJ@74201,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain JOKFNDED_04913 278957.ABEA03000099_gene860 8.7e-22 111.3 Opitutae Bacteria 2CAB8@1,33EYG@2,3K9KC@414999,46XII@74201 NA|NA|NA JOKFNDED_04914 469383.Cwoe_4808 2.9e-14 85.5 Bacteria Bacteria 2DQ8V@1,32UNN@2 NA|NA|NA JOKFNDED_04915 1396141.BATP01000060_gene4597 9.6e-73 281.2 Bacteria dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria COG2027@1,COG2027@2 NA|NA|NA M serine-type D-Ala-D-Ala carboxypeptidase activity JOKFNDED_04917 1124982.MSI_23740 2.2e-19 101.3 Spirochaetes rpmE ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2J93Z@203691,COG0254@1,COG0254@2 NA|NA|NA J 50S ribosomal protein L31 JOKFNDED_04918 1123229.AUBC01000001_gene1837 4.9e-37 161.4 Bradyrhizobiaceae Bacteria 1N39M@1224,2E61B@1,2U8C9@28211,330QK@2,3JZ9V@41294 NA|NA|NA JOKFNDED_04919 1123070.KB899254_gene1225 6.2e-28 131.0 Verrucomicrobiae rfaY ko:K03088 ko00000,ko03021 Bacteria 2IVUN@203494,46XGG@74201,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_04920 1123070.KB899254_gene1226 3.9e-132 479.2 Verrucomicrobiae yfbK ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2ITP9@203494,46SHE@74201,COG2304@1,COG2304@2 NA|NA|NA S Domain of unknown function (DUF3520) JOKFNDED_04921 1403819.BATR01000104_gene3620 2.3e-136 492.3 Verrucomicrobiae hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iUTI89_1310.UTI89_C2293,ic_1306.c2547 Bacteria 2ITG9@203494,46SHG@74201,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine JOKFNDED_04922 1403819.BATR01000104_gene3619 3.8e-66 258.5 Verrucomicrobiae 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 2ITU3@203494,46SYW@74201,COG1092@1,COG1092@2 NA|NA|NA J S-adenosylmethionine-dependent methyltransferase JOKFNDED_04923 1396418.BATQ01000129_gene4818 8.8e-212 743.4 Verrucomicrobiae pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITGG@203494,46SB1@74201,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III JOKFNDED_04925 497964.CfE428DRAFT_0520 2.7e-13 81.6 Verrucomicrobia Bacteria 46WDF@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_04926 240016.ABIZ01000001_gene4273 4.3e-45 187.6 Verrucomicrobiae Bacteria 2IUMM@203494,46VKZ@74201,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain JOKFNDED_04928 1396141.BATP01000030_gene3629 1.7e-36 160.2 Verrucomicrobiae deaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2ITPY@203494,46U0S@74201,COG0513@1,COG0513@2 NA|NA|NA L DbpA RNA binding domain JOKFNDED_04929 886293.Sinac_5104 1.9e-19 102.8 Planctomycetes glgE 2.4.99.16,3.2.1.14 ko:K01183,ko:K12684,ko:K16147 ko00500,ko00520,ko01100,map00500,map00520,map01100 R01206,R02334,R09994 RC00467 ko00000,ko00001,ko01000,ko02000,ko02044 1.B.12.4 GH13,GH18 Bacteria 2J1BR@203682,COG3468@1,COG3468@2 NA|NA|NA MU outer membrane autotransporter barrel domain protein JOKFNDED_04930 1396141.BATP01000023_gene490 2.3e-27 127.9 Verrucomicrobiae Bacteria 2C1W8@1,2IUVQ@203494,2ZXK7@2,46WJJ@74201 NA|NA|NA S Zinc ribbon domain JOKFNDED_04931 1396141.BATP01000023_gene491 2.2e-33 147.9 Verrucomicrobiae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUM9@203494,46TBH@74201,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site JOKFNDED_04932 1121035.AUCH01000008_gene991 1.5e-10 73.6 Betaproteobacteria Bacteria 1Q1D9@1224,2AIIY@1,2W6JH@28216,31911@2 NA|NA|NA JOKFNDED_04933 583355.Caka_1121 8e-170 603.2 Opitutae 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7M0@414999,46TGU@74201,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase JOKFNDED_04934 794903.OPIT5_26850 4.1e-117 427.9 Opitutae 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 3K7HE@414999,46UA8@74201,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase JOKFNDED_04935 1396141.BATP01000057_gene3046 4.8e-12 77.0 Verrucomicrobiae Bacteria 2AVZM@1,2IUMV@203494,31MU0@2,46X67@74201 NA|NA|NA JOKFNDED_04936 1074488.AGBX01000001_gene1201 8e-17 93.6 Dermabacteraceae iscR 2.8.1.7 ko:K04487,ko:K13643 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03000,ko03016,ko03029 Bacteria 2INF3@201174,4FDS6@85020,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator JOKFNDED_04937 314230.DSM3645_07211 2e-57 229.6 Planctomycetes Bacteria 2J007@203682,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase JOKFNDED_04938 1210884.HG799462_gene7952 6.8e-264 917.1 Planctomycetes Bacteria 2J53S@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04939 886293.Sinac_5600 8e-186 656.8 Planctomycetes Bacteria 2IX5T@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04940 103690.17131131 1.2e-96 360.1 Nostocales mdsC 2.7.1.162,2.7.1.39 ko:K02204,ko:K13059 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771,R08962 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1G1QD@1117,1HIXP@1161,COG2334@1,COG2334@2 NA|NA|NA S PFAM Phosphotransferase enzyme family JOKFNDED_04943 1150469.RSPPHO_01635 1.1e-17 97.1 Rhodospirillales yahN GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K03329 ko00000,ko02000 2.A.76.1.3 Bacteria 1N227@1224,2JS9J@204441,2UCZW@28211,COG1280@1,COG1280@2 NA|NA|NA E LysE type translocator JOKFNDED_04945 1127131.WEISSC39_07320 1.1e-16 94.7 Leuconostocaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,4AWY7@81850,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family JOKFNDED_04946 1313172.YM304_42000 1.6e-07 65.1 Bacteria Bacteria COG2373@1,COG2373@2 NA|NA|NA U Large extracellular alpha-helical protein JOKFNDED_04948 497964.CfE428DRAFT_2146 7.7e-64 251.1 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46VAM@74201,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_04949 1396141.BATP01000022_gene326 1.3e-237 828.9 Verrucomicrobiae glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 2ITMG@203494,46TEV@74201,COG0423@1,COG0423@2 NA|NA|NA J Anticodon binding domain JOKFNDED_04950 1123070.KB899268_gene2442 7.6e-26 122.9 Verrucomicrobiae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUUU@203494,46TBF@74201,COG0227@1,COG0227@2 NA|NA|NA J Ribosomal L28 family JOKFNDED_04952 1396141.BATP01000030_gene3755 1.6e-24 118.6 Verrucomicrobiae clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 2IUSR@203494,46T8N@74201,COG2127@1,COG2127@2 NA|NA|NA S ATP-dependent Clp protease adaptor protein ClpS JOKFNDED_04953 1254432.SCE1572_16745 4.3e-43 181.4 Deltaproteobacteria SEN0012 Bacteria 1N1ZN@1224,2WR5Q@28221,42V02@68525,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family JOKFNDED_04954 1216007.AOPM01000075_gene1244 5.9e-47 194.1 Pseudoalteromonadaceae yijF ko:K09974 ko00000 Bacteria 1RE1M@1224,1S44B@1236,2Q0M8@267888,COG3738@1,COG3738@2 NA|NA|NA S Domain of unknown function (DUF1287) JOKFNDED_04955 497964.CfE428DRAFT_0265 8.5e-194 683.3 Verrucomicrobia gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 46U4C@74201,COG0696@1,COG0696@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate JOKFNDED_04956 1396141.BATP01000047_gene3941 4.9e-49 201.8 Verrucomicrobiae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUDS@203494,46SX9@74201,COG4589@1,COG4589@2 NA|NA|NA S Cytidylyltransferase family JOKFNDED_04957 1396141.BATP01000047_gene3942 8.9e-143 513.5 Verrucomicrobiae dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2ITI1@203494,46S90@74201,COG0743@1,COG0743@2 NA|NA|NA I 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal JOKFNDED_04963 1499967.BAYZ01000032_gene1150 1.3e-169 604.0 Bacteria Bacteria COG2319@1,COG2319@2,COG4249@1,COG4249@2 NA|NA|NA S B-1 B cell differentiation JOKFNDED_04964 344747.PM8797T_11229 5.7e-158 564.3 Planctomycetes Bacteria 2IX69@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_04965 314230.DSM3645_02158 4.6e-307 1060.4 Planctomycetes Bacteria 2IXBF@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_04966 1304885.AUEY01000096_gene2839 5e-123 448.7 Desulfobacterales cglB GO:0005575,GO:0005576 ko:K12287 ko00000,ko02044 Bacteria 1P8N9@1224,2MNHJ@213118,2X72D@28221,43DXZ@68525,COG1404@1,COG1404@2,COG2304@1,COG2304@2,COG2911@1,COG2911@2,COG3897@1,COG3897@2,COG5434@1,COG5434@2 NA|NA|NA M pectinesterase activity JOKFNDED_04967 240016.ABIZ01000001_gene3859 2.6e-90 338.6 Verrucomicrobiae Bacteria 2ITSE@203494,46SNA@74201,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain JOKFNDED_04968 118005.AWNK01000007_gene697 2.2e-114 419.5 Bacteria ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iSbBS512_1146.SbBS512_E2875 Bacteria COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) JOKFNDED_04969 1396141.BATP01000030_gene3612 4.2e-127 462.2 Verrucomicrobiae 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITUP@203494,46YYE@74201,COG2833@1,COG2833@2 NA|NA|NA I Protein of unknown function (DUF455) JOKFNDED_04970 240016.ABIZ01000001_gene4855 8.1e-71 275.0 Verrucomicrobiae ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 2IU8Z@203494,46T0M@74201,COG0795@1,COG0795@2 NA|NA|NA S Predicted permease YjgP/YjgQ family JOKFNDED_04971 1396418.BATQ01000163_gene1984 2e-32 146.4 Verrucomicrobiae Bacteria 2EKW2@1,2IW0A@203494,33EJK@2,46VZV@74201 NA|NA|NA JOKFNDED_04972 240016.ABIZ01000001_gene3861 2.9e-91 342.0 Verrucomicrobia Bacteria 46U5Z@74201,COG0657@1,COG0657@2 NA|NA|NA I Protein of unknown function (DUF1460) JOKFNDED_04973 1279038.KB907355_gene2119 2.3e-62 247.3 Rhodospirillales MA20_09210 ko:K07003 ko00000 Bacteria 1MUE1@1224,2JSYA@204441,2TRI9@28211,COG0664@1,COG0664@2,COG1033@1,COG1033@2 NA|NA|NA T Sterol-sensing domain of SREBP cleavage-activation JOKFNDED_04976 1396418.BATQ01000059_gene2068 3.3e-176 624.8 Verrucomicrobia Bacteria 46UAB@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_04978 243090.RB900 2e-156 559.3 Planctomycetes Bacteria 2IXCN@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_04979 1552758.NC00_13130 8e-23 113.6 Xanthomonadales ko:K09940 ko00000 Bacteria 1N4ZK@1224,1RTU4@1236,1X7NI@135614,COG3296@1,COG3296@2 NA|NA|NA S Domain of unknown function (DUF4870) JOKFNDED_04980 497964.CfE428DRAFT_2893 3.4e-83 314.7 Verrucomicrobia queC 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 R09978 RC00959 ko00000,ko00001,ko01000,ko03016 Bacteria 46SEU@74201,COG0603@1,COG0603@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) JOKFNDED_04981 1396141.BATP01000040_gene2139 9.8e-50 203.0 Verrucomicrobiae queF 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 R07605 RC01875 ko00000,ko00001,ko01000,ko03016 Bacteria 2IUI4@203494,46SYQ@74201,COG0780@1,COG0780@2 NA|NA|NA S QueF-like protein JOKFNDED_04982 240016.ABIZ01000001_gene5532 1.5e-35 157.1 Verrucomicrobiae ko:K03286,ko:K03640 ko00000,ko02000 1.B.6,2.C.1.2 Bacteria 2IUNT@203494,46T6J@74201,COG2885@1,COG2885@2 NA|NA|NA M OmpA family JOKFNDED_04983 1128421.JAGA01000003_gene2905 3.8e-91 342.4 Bacteria Bacteria COG3011@1,COG3011@2 NA|NA|NA CH Protein conserved in bacteria JOKFNDED_04984 1123508.JH636440_gene2248 1.4e-23 116.3 Bacteria Bacteria 2E1Y1@1,32X6X@2 NA|NA|NA JOKFNDED_04985 658086.HMPREF0994_06434 1e-54 221.5 Firmicutes Bacteria 1VSII@1239,COG1621@1,COG1621@2 NA|NA|NA G beta-fructofuranosidase activity JOKFNDED_04987 1396418.BATQ01000182_gene938 7.8e-27 126.7 Verrucomicrobiae Bacteria 2IVXF@203494,46XHD@74201,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family JOKFNDED_04988 794903.OPIT5_17305 9.8e-55 219.5 Opitutae fucU GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016853,GO:0016854,GO:0016857,GO:0030246,GO:0036094,GO:0042806,GO:0044424,GO:0044464,GO:0048029 5.1.3.29 ko:K02431 R10764 RC00563 ko00000,ko01000 Bacteria 3K9HI@414999,46VZ8@74201,COG4154@1,COG4154@2 NA|NA|NA G RbsD / FucU transport protein family JOKFNDED_04989 1123242.JH636435_gene2146 1.1e-127 463.4 Planctomycetes Bacteria 2IXXG@203682,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_04990 240016.ABIZ01000001_gene4871 2e-58 233.0 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_04991 1123070.KB899255_gene1313 1.3e-81 310.1 Verrucomicrobiae Bacteria 2EZMG@1,2IU6Q@203494,33SSM@2,46UUT@74201 NA|NA|NA JOKFNDED_04994 426117.M446_5947 1.7e-50 206.1 Methylobacteriaceae mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 ko:K02428,ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 Bacteria 1JTN3@119045,1MVKM@1224,2TRC9@28211,COG1694@1,COG3956@2 NA|NA|NA S PFAM MazG nucleotide pyrophosphohydrolase JOKFNDED_04995 240016.ABIZ01000001_gene50 1.8e-25 122.5 Verrucomicrobiae Bacteria 2EMM1@1,2IUX2@203494,33F9E@2,46TBT@74201 NA|NA|NA JOKFNDED_04996 1396418.BATQ01000003_gene1352 1.6e-21 109.4 Verrucomicrobiae Bacteria 2IURI@203494,46T4Z@74201,COG1366@1,COG1366@2 NA|NA|NA T STAS domain JOKFNDED_04997 1396141.BATP01000007_gene5783 3.6e-93 349.0 Verrucomicrobiae rsbU 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 2ITX4@203494,46SWK@74201,COG2203@1,COG2203@2,COG2208@1,COG2208@2 NA|NA|NA T Sigma factor PP2C-like phosphatases JOKFNDED_04998 240016.ABIZ01000001_gene5662 1.6e-39 169.5 Verrucomicrobiae grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 ko:K03687 ko00000,ko03029,ko03110 Bacteria 2IUHJ@203494,46T79@74201,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ JOKFNDED_04999 497964.CfE428DRAFT_3655 8.3e-117 427.2 Verrucomicrobia dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 ko:K03686 ko00000,ko03029,ko03110 Bacteria 46TKC@74201,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins JOKFNDED_05001 314230.DSM3645_18596 5.7e-115 420.6 Planctomycetes ko:K07045 ko00000 Bacteria 2IXTD@203682,COG2159@1,COG2159@2 NA|NA|NA S TIM-barrel fold JOKFNDED_05002 903818.KI912268_gene871 7.2e-132 477.2 Bacteria ko:K07133 ko00000 Bacteria COG1373@1,COG1373@2 NA|NA|NA V ATPase (AAA superfamily JOKFNDED_05003 595460.RRSWK_05284 4.1e-213 748.8 Planctomycetes 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 2J1WG@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_05005 1396418.BATQ01000071_gene523 5.3e-120 438.0 Verrucomicrobia Bacteria 46S6X@74201,COG2755@1,COG2755@2 NA|NA|NA E Acyl-CoA thioesterase JOKFNDED_05006 530564.Psta_1455 6.3e-296 1023.5 Planctomycetes ko:K09992 ko00000 Bacteria 2IWZR@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Cytochrome c JOKFNDED_05007 382464.ABSI01000005_gene1378 9.3e-58 232.6 Verrucomicrobiae Bacteria 2IVF7@203494,46WEI@74201,COG1262@1,COG1262@2 NA|NA|NA N Sulfatase-modifying factor enzyme 1 JOKFNDED_05009 240016.ABIZ01000001_gene2835 5.5e-82 310.8 Verrucomicrobia ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 46TZ8@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_05010 583355.Caka_0520 5.7e-92 344.4 Bacteria 1.1.1.122 ko:K00064 ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120 M00114 R07675,R08926 RC00066,RC00161 ko00000,ko00001,ko00002,ko01000 Bacteria COG0667@1,COG0667@2 NA|NA|NA C Aldo Keto reductase JOKFNDED_05011 1396418.BATQ01000047_gene6221 1.3e-97 363.6 Verrucomicrobiae Bacteria 2ITZ3@203494,46TM9@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_05012 237368.SCABRO_00502 9.5e-30 137.5 Bacteria ycbC GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 Bacteria COG1434@1,COG1434@2 NA|NA|NA S Gram-negative-bacterium-type cell wall biogenesis JOKFNDED_05013 1396418.BATQ01000147_gene3565 1.3e-36 159.8 Verrucomicrobiae yihX GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 ko:K01560,ko:K07025,ko:K20866,ko:K21063 ko00010,ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00010,map00361,map00625,map00740,map01100,map01110,map01120 M00125 R00947,R05287,R07280 RC00017,RC00078,RC00697 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUM3@203494,46VA2@74201,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase JOKFNDED_05015 313628.LNTAR_12216 1.2e-180 641.0 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_05016 313628.LNTAR_08764 4.1e-27 129.0 Bacteria Bacteria 2F8GG@1,340VA@2 NA|NA|NA JOKFNDED_05017 344747.PM8797T_31638 1.9e-100 373.2 Planctomycetes modA2 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464 ko:K02020 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria 2J08C@203682,COG0725@1,COG0725@2 NA|NA|NA P Bacterial extracellular solute-binding protein JOKFNDED_05018 497964.CfE428DRAFT_1996 3.9e-78 298.1 Bacteria modB1 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02018 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria COG0555@1,COG0555@2 NA|NA|NA P ATPase-coupled sulfate transmembrane transporter activity JOKFNDED_05019 497964.CfE428DRAFT_1995 1.4e-65 256.1 Bacteria 3.6.3.29,3.6.3.55 ko:K02017,ko:K15497 ko02010,map02010 M00189,M00423 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.5,3.A.1.8 Bacteria COG3842@1,COG3842@2 NA|NA|NA P ATPase activity JOKFNDED_05020 344747.PM8797T_31618 6.1e-87 327.4 Planctomycetes hesA Bacteria 2IY5K@203682,COG0476@1,COG0476@2 NA|NA|NA H ThiF family JOKFNDED_05021 530564.Psta_0578 1.8e-50 206.5 Planctomycetes Bacteria 2DI2U@1,2J0HD@203682,301UZ@2 NA|NA|NA JOKFNDED_05022 344747.PM8797T_27894 6.7e-11 75.9 Bacteria Bacteria COG1572@1,COG1572@2,COG3391@1,COG3391@2 NA|NA|NA NU bacterial-type flagellum-dependent cell motility JOKFNDED_05023 448385.sce6745 2.3e-54 221.1 Myxococcales Bacteria 1MWRF@1224,2WJI7@28221,2YTSQ@29,42P9S@68525,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA H CHAT domain JOKFNDED_05024 344747.PM8797T_08574 1.8e-75 290.8 Planctomycetes 3.2.1.172 ko:K15532 ko00000,ko01000 GH105 Bacteria 2IZFK@203682,COG4225@1,COG4225@2 NA|NA|NA S unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins JOKFNDED_05025 926569.ANT_07600 6.6e-78 297.4 Chloroflexi hisN 3.1.3.15,3.1.3.25 ko:K01092,ko:K05602 ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070 M00026,M00131 R01185,R01186,R01187,R03013 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2G7NN@200795,COG0483@1,COG0483@2 NA|NA|NA G PFAM inositol monophosphatase JOKFNDED_05029 240016.ABIZ01000001_gene2482 5.1e-31 140.6 Verrucomicrobiae gspG_1 ko:K02246,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 2IURN@203494,46W6A@74201,COG2165@1,COG2165@2 NA|NA|NA NU Type II secretion system (T2SS), protein G JOKFNDED_05030 240016.ABIZ01000001_gene2481 3.2e-82 312.4 Verrucomicrobiae pilC ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2IU50@203494,46X1U@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_05031 240016.ABIZ01000001_gene2480 5.9e-175 620.9 Verrucomicrobiae xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2ITRF@203494,46TUR@74201,COG2804@1,COG2804@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_05032 530564.Psta_2956 8.7e-88 330.5 Planctomycetes ko:K09992 ko00000 Bacteria 2IXKV@203682,COG1413@1,COG1413@2,COG2133@1,COG2133@2 NA|NA|NA C Membrane-bound dehydrogenase domain JOKFNDED_05034 640081.Dsui_1553 3.4e-21 107.8 Rhodocyclales tfoX ko:K07343 ko00000 Bacteria 1N8X8@1224,2KXCR@206389,2VVUD@28216,COG3070@1,COG3070@2 NA|NA|NA K TfoX N-terminal domain JOKFNDED_05035 344747.PM8797T_03810 3.4e-29 134.8 Planctomycetes Bacteria 2E958@1,2J3KT@203682,333E0@2 NA|NA|NA JOKFNDED_05036 794903.OPIT5_26855 1.8e-140 505.8 Opitutae 1.1.1.337 ko:K05884 ko00680,map00680 M00358 R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7H8@414999,46YXK@74201,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family JOKFNDED_05038 583355.Caka_1327 1.2e-114 419.5 Verrucomicrobia thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 46SCY@74201,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis JOKFNDED_05039 240016.ABIZ01000001_gene976 1e-36 159.8 Verrucomicrobiae folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2IUNY@203494,46T19@74201,COG0262@1,COG0262@2 NA|NA|NA H Dihydrofolate reductase JOKFNDED_05041 1123242.JH636434_gene4399 2e-159 568.9 Planctomycetes 3.4.24.3 ko:K01387 ko00000,ko01000,ko01002,ko02042 Bacteria 2IX4C@203682,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) JOKFNDED_05042 1142394.PSMK_12930 1.2e-21 110.9 Planctomycetes Bacteria 2IWZY@203682,COG0673@1,COG0673@2 NA|NA|NA G Oxidoreductase JOKFNDED_05043 344747.PM8797T_09084 1.2e-146 526.2 Bacteria 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria COG1262@1,COG1262@2 NA|NA|NA T PFAM Formylglycine-generating sulfatase enzyme JOKFNDED_05044 497964.CfE428DRAFT_4244 1.4e-300 1039.3 Verrucomicrobia Bacteria 46TVM@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C HEAT repeats JOKFNDED_05045 1123070.KB899266_gene2496 7.4e-14 83.2 Verrucomicrobiae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IUQD@203494,46W29@74201,COG1758@1,COG1758@2 NA|NA|NA K RNA polymerase activity JOKFNDED_05046 1396418.BATQ01000001_gene1263 5.9e-294 1016.5 Verrucomicrobiae uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2ITYA@203494,46SF2@74201,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage JOKFNDED_05049 675814.VIC_001313 9.5e-21 107.5 Vibrionales Bacteria 1MXRV@1224,1SEJ5@1236,1XZ1Y@135623,2Z9DH@2,arCOG09511@1 NA|NA|NA S FRG JOKFNDED_05050 1123070.KB899251_gene684 4.2e-69 268.1 Verrucomicrobiae queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 Bacteria 2IUF0@203494,46SW0@74201,COG0602@1,COG0602@2 NA|NA|NA O Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds JOKFNDED_05051 1396418.BATQ01000020_gene5048 1.7e-63 250.0 Verrucomicrobiae Bacteria 28J0S@1,2IVRQ@203494,2Z8XX@2,46SX2@74201 NA|NA|NA JOKFNDED_05052 794903.OPIT5_07190 1.6e-80 307.0 Opitutae Bacteria 3K946@414999,46URZ@74201,COG0745@1,COG0745@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase JOKFNDED_05054 1123070.KB899260_gene2079 4.4e-21 107.8 Verrucomicrobiae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUVZ@203494,46T87@74201,COG0184@1,COG0184@2 NA|NA|NA J Ribosomal_S15 JOKFNDED_05055 497964.CfE428DRAFT_5372 1.3e-28 133.3 Verrucomicrobia 3.4.21.53 ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 46WE2@74201,COG0466@1,COG0466@2 NA|NA|NA O PFAM peptidase S16 lon domain protein JOKFNDED_05056 1123242.JH636435_gene2596 3.2e-10 71.6 Planctomycetes Bacteria 2DFEN@1,2J4FV@203682,2ZRK7@2 NA|NA|NA JOKFNDED_05057 497964.CfE428DRAFT_0715 1.8e-168 598.6 Verrucomicrobia Bacteria 46TGS@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_05058 402881.Plav_2239 3.3e-19 102.1 Alphaproteobacteria Bacteria 1NMXG@1224,2ERA8@1,2UKSQ@28211,33IVV@2 NA|NA|NA JOKFNDED_05059 240016.ABIZ01000001_gene4590 2.8e-86 325.9 Verrucomicrobia Bacteria 2A84C@1,30X53@2,46SPC@74201 NA|NA|NA JOKFNDED_05060 382464.ABSI01000009_gene3987 1.1e-42 181.0 Verrucomicrobia ko:K07234 ko00000 Bacteria 46VTH@74201,COG3213@1,COG3213@2 NA|NA|NA P NnrS protein JOKFNDED_05061 452637.Oter_1779 2.6e-92 345.1 Opitutae yisS Bacteria 3KA2V@414999,46U36@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_05062 497964.CfE428DRAFT_3744 8.8e-50 203.8 Verrucomicrobia Bacteria 46SUS@74201,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain JOKFNDED_05063 1396141.BATP01000059_gene2617 6e-166 590.5 Verrucomicrobiae ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2IU0D@203494,46SAR@74201,COG0761@1,COG0761@2 NA|NA|NA IM LytB protein JOKFNDED_05064 344747.PM8797T_15676 2.3e-236 825.9 Planctomycetes 3.5.1.104 ko:K02305,ko:K08738,ko:K22278 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.10,3.D.4.6 Bacteria 2IXJQ@203682,COG0726@1,COG0726@2,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3474@1,COG3474@2 NA|NA|NA C polysaccharide deacetylase JOKFNDED_05065 530564.Psta_1182 2.8e-38 166.4 Planctomycetes Bacteria 2IZ7E@203682,COG1262@1,COG1262@2 NA|NA|NA KLT Sulfatase-modifying factor enzyme 1 JOKFNDED_05066 344747.PM8797T_08389 3.2e-179 634.8 Planctomycetes Bacteria 2IWVH@203682,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane JOKFNDED_05067 1173028.ANKO01000135_gene2511 4.9e-63 248.8 Oscillatoriales Bacteria 1G09B@1117,1H7M6@1150,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_05068 266834.SMc00389 5.9e-33 148.3 Alphaproteobacteria Bacteria 1RA18@1224,28PFN@1,2U6F5@28211,2ZC6T@2 NA|NA|NA JOKFNDED_05069 1403819.BATR01000185_gene6430 1.6e-73 285.4 Verrucomicrobiae 3.1.3.8 ko:K01083,ko:K07346 ko00562,map00562 R03371 RC00078 ko00000,ko00001,ko01000,ko02035,ko02044,ko03110 Bacteria 2IVEQ@203494,46Z9Q@74201,COG3121@1,COG3121@2,COG3204@1,COG3204@2,COG3291@1,COG3291@2,COG3506@1,COG3506@2,COG5184@1,COG5184@2 NA|NA|NA DEGMUZ Repeats in polycystic kidney disease 1 (PKD1) and other proteins JOKFNDED_05070 1210884.HG799466_gene12785 3.4e-20 105.1 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J3Y8@203682,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 JOKFNDED_05071 240016.ABIZ01000001_gene2902 2.6e-55 222.2 Verrucomicrobiae greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2ITY2@203494,46S7F@74201,COG0782@1,COG0782@2,COG1747@1,COG1747@2 NA|NA|NA K Transcription elongation factor, N-terminal JOKFNDED_05072 1121875.KB907556_gene572 9e-91 340.5 Flavobacteriia ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 1I7Q6@117743,4NM2C@976,COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins JOKFNDED_05073 264198.Reut_A0184 4.7e-93 348.6 Burkholderiaceae Bacteria 1KCEV@119060,1N17V@1224,2VH7Q@28216,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor JOKFNDED_05074 216591.BCAM1998 5.9e-65 254.2 Burkholderiaceae Bacteria 1KGNN@119060,1MVCB@1224,2VQH1@28216,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal JOKFNDED_05075 240016.ABIZ01000001_gene4758 2.1e-34 152.5 Verrucomicrobiae Bacteria 296GV@1,2IUJX@203494,2ZTSD@2,46WKD@74201 NA|NA|NA JOKFNDED_05076 1396141.BATP01000045_gene1748 6.7e-23 113.2 Verrucomicrobiae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2IUR4@203494,46WCW@74201,COG0571@1,COG0571@2 NA|NA|NA K ribonuclease III activity JOKFNDED_05077 1396418.BATQ01000054_gene26 5e-76 291.2 Verrucomicrobiae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 2IU4G@203494,46UDA@74201,COG1281@1,COG1281@2 NA|NA|NA O Hsp33 protein JOKFNDED_05078 240016.ABIZ01000001_gene1420 3.8e-08 64.7 Bacteria ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria COG0664@1,COG0664@2 NA|NA|NA T cyclic nucleotide binding JOKFNDED_05080 1396418.BATQ01000008_gene1471 1.2e-25 122.9 Verrucomicrobiae fcbC ko:K07107 ko00000,ko01000 Bacteria 2IUDB@203494,46T37@74201,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily JOKFNDED_05082 1396418.BATQ01000072_gene581 4.1e-98 364.8 Verrucomicrobiae hyuA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016885,GO:0017144,GO:0018710,GO:0042180,GO:0043443,GO:0044237,GO:0044281,GO:0071704,GO:1901568,GO:1902224 3.5.2.14,3.5.2.9,6.4.1.6,6.4.1.8 ko:K01469,ko:K01473,ko:K01474,ko:K10701,ko:K10855 ko00330,ko00480,ko00642,ko01100,ko01120,ko01220,map00330,map00480,map00642,map01100,map01120,map01220 R00251,R03187,R05453 RC00040,RC00553,RC00632 ko00000,ko00001,ko01000 iNJ661.Rv0266c Bacteria 2IU32@203494,46UMR@74201,COG0145@1,COG0145@2,COG0146@1,COG0146@2 NA|NA|NA EQ Hydantoinase B/oxoprolinase JOKFNDED_05083 1123242.JH636435_gene1839 4.5e-103 381.7 Planctomycetes Bacteria 2IWRC@203682,COG0673@1,COG0673@2 NA|NA|NA S COGs COG0673 dehydrogenase and related protein JOKFNDED_05084 314230.DSM3645_29082 8.4e-115 420.2 Planctomycetes araC 4.2.1.82,4.2.1.9 ko:K01687,ko:K22186 ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02429,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYTK@203682,COG0129@1,COG0129@2 NA|NA|NA EG Dehydratase family JOKFNDED_05087 886293.Sinac_4922 1.4e-64 253.1 Planctomycetes Bacteria 2IX26@203682,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase JOKFNDED_05088 1396141.BATP01000002_gene4851 2.1e-145 522.7 Verrucomicrobia fhaC5 Bacteria 46TZ0@74201,COG2831@1,COG2831@2 NA|NA|NA U Hemin-binding protein JOKFNDED_05089 794903.OPIT5_06290 3.1e-172 612.1 Opitutae exbB ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 3K97F@414999,46X1Q@74201,COG0811@1,COG0811@2 NA|NA|NA U Domain of unknown function (DUF2341) JOKFNDED_05090 794903.OPIT5_06295 1.4e-47 195.7 Opitutae exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 3K9GK@414999,46Z0Y@74201,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR JOKFNDED_05091 794903.OPIT5_08945 5.2e-29 134.8 Opitutae tonB2 ko:K03832,ko:K07277 ko00000,ko02000,ko03029 1.B.33,2.C.1.1 Bacteria 3K9KR@414999,46WBE@74201,COG0810@1,COG0810@2 NA|NA|NA M TonB C terminal JOKFNDED_05092 1396141.BATP01000047_gene3992 2.5e-148 532.7 Verrucomicrobia Bacteria 46UUD@74201,COG3746@1,COG3746@2 NA|NA|NA P Putative porin JOKFNDED_05093 1396141.BATP01000002_gene4857 7.2e-29 134.4 Bacteria Bacteria 2CAN2@1,32RI0@2 NA|NA|NA JOKFNDED_05094 1396141.BATP01000002_gene4858 4.2e-63 248.4 Bacteria 5.2.1.8 ko:K01802,ko:K03769 ko00000,ko01000,ko03110 Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity JOKFNDED_05096 861299.J421_6347 5.7e-31 141.4 Bacteria Bacteria 2925T@1,2ZPQR@2 NA|NA|NA JOKFNDED_05097 497964.CfE428DRAFT_6667 9.9e-94 350.1 Verrucomicrobia Bacteria 46UG0@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_05098 177439.DP1520 4.2e-82 315.1 Desulfobacterales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1MXIP@1224,2MNJ9@213118,2WQ54@28221,42TFA@68525,COG3210@1,COG3210@2 NA|NA|NA U haemagglutination activity domain JOKFNDED_05099 639030.JHVA01000001_gene920 1.5e-114 420.6 Acidobacteriia dsbD 1.8.1.8 ko:K04084,ko:K08344 ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.5 Bacteria 2JIRQ@204432,3Y2KW@57723,COG4232@1,COG4232@2,COG4233@1,COG4233@2 NA|NA|NA CO Disulphide bond corrector protein DsbC JOKFNDED_05100 44251.PDUR_06610 5e-30 138.3 Paenibacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,26SCR@186822,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase JOKFNDED_05101 1267535.KB906767_gene1678 7.9e-86 323.9 Bacteria Bacteria COG2159@1,COG2159@2 NA|NA|NA E amidohydrolase JOKFNDED_05102 497964.CfE428DRAFT_1840 8.1e-163 581.3 Verrucomicrobia ko:K02305,ko:K08738 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 Bacteria 46TEP@74201,COG3474@1,COG3474@2 NA|NA|NA C Cytochrome c JOKFNDED_05103 1403819.BATR01000118_gene4082 4.3e-63 248.4 Verrucomicrobia ko:K07088 ko00000 Bacteria 46WH0@74201,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein JOKFNDED_05105 1396141.BATP01000006_gene5445 2.5e-75 288.5 Verrucomicrobiae Bacteria 2IW0I@203494,46SR1@74201,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_05106 186497.PF0319 1.8e-64 253.1 Thermococci gyaR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26,1.1.1.29 ko:K00015,ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Archaea 2432P@183968,2XVDY@28890,COG1052@1,arCOG01755@2157 NA|NA|NA C glyoxylate reductase activity JOKFNDED_05107 1142394.PSMK_16320 5.6e-93 347.8 Planctomycetes yjjN GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034193,GO:0034195,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 iSSON_1240.SSON_4504 Bacteria 2IY5A@203682,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES domain protein JOKFNDED_05108 1123070.KB899268_gene2405 3e-237 827.8 Verrucomicrobiae fumB GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676,ko:K01677,ko:K01678 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_1778,iPC815.YPO3335 Bacteria 2IU09@203494,46UJW@74201,COG1838@1,COG1838@2,COG1951@1,COG1951@2 NA|NA|NA C Catalyzes the reversible hydration of fumarate to (S)- malate JOKFNDED_05109 1396418.BATQ01000137_gene3884 9.1e-197 693.3 Verrucomicrobiae phnV ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 2IU10@203494,46SFB@74201,COG1178@1,COG1178@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component JOKFNDED_05110 1403819.BATR01000125_gene4479 8.1e-26 123.6 Verrucomicrobiae yraN ko:K07460 ko00000 Bacteria 2IUV7@203494,46T9J@74201,COG0792@1,COG0792@2 NA|NA|NA L Uncharacterised protein family UPF0102 JOKFNDED_05111 1403819.BATR01000125_gene4480 1.2e-64 253.1 Verrucomicrobiae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2IU98@203494,46SXH@74201,COG0164@1,COG0164@2 NA|NA|NA L Ribonuclease HII JOKFNDED_05112 497964.CfE428DRAFT_5385 3.8e-111 408.3 Verrucomicrobia fas6 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 46SEG@74201,COG1611@1,COG1611@2 NA|NA|NA S Possible lysine decarboxylase JOKFNDED_05113 42256.RradSPS_0870 1.3e-116 426.4 Rubrobacteria aroG 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMVF@201174,4CSEZ@84995,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) JOKFNDED_05114 583355.Caka_3042 4.1e-172 610.9 Opitutae purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0389,iSDY_1059.SDY_1135 Bacteria 3K78S@414999,46ZBN@74201,COG0027@1,COG0027@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate JOKFNDED_05115 497964.CfE428DRAFT_3408 1.6e-92 347.1 Verrucomicrobia ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 28M0D@1,2ZAFE@2,46TXJ@74201 NA|NA|NA S Putative ATP-binding cassette JOKFNDED_05116 1396418.BATQ01000113_gene4665 1e-18 100.5 Verrucomicrobiae Bacteria 2FHDV@1,2IURW@203494,34981@2,46W9B@74201 NA|NA|NA JOKFNDED_05118 1403819.BATR01000114_gene3905 5.9e-181 640.6 Bacteria Bacteria COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_05119 1403819.BATR01000114_gene3901 1.4e-254 885.9 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_05120 240016.ABIZ01000001_gene2578 2.5e-62 246.5 Verrucomicrobia Bacteria 299VH@1,2ZWXI@2,46WR6@74201 NA|NA|NA JOKFNDED_05123 314230.DSM3645_14185 2e-60 239.6 Planctomycetes Bacteria 2IX14@203682,COG1680@1,COG1680@2 NA|NA|NA V COG1680 Beta-lactamase class C and other penicillin binding JOKFNDED_05124 1031711.RSPO_c02957 3e-34 151.8 Burkholderiaceae gntK 1.1.1.343,1.1.1.44,2.7.1.12,2.7.1.71 ko:K00033,ko:K00851,ko:K00891 ko00030,ko00400,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map00480,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00006,M00022 R01528,R01737,R02412,R10221 RC00001,RC00002,RC00017,RC00078,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1KGAQ@119060,1RHD0@1224,2VSY0@28216,COG3265@1,COG3265@2 NA|NA|NA F Gluconokinase JOKFNDED_05125 1396418.BATQ01000182_gene854 3e-64 252.3 Verrucomicrobia Bacteria 46SZK@74201,COG0859@1,COG0859@2 NA|NA|NA M Glycosyltransferase family 9 (heptosyltransferase) JOKFNDED_05127 1403819.BATR01000147_gene5033 1.1e-112 413.7 Verrucomicrobiae murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2ITUQ@203494,46SDF@74201,COG0770@1,COG0770@2 NA|NA|NA M Mur ligase middle domain JOKFNDED_05128 240016.ABIZ01000001_gene3513 1.8e-140 506.1 Verrucomicrobiae murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2158c Bacteria 2ITRP@203494,46SGG@74201,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan JOKFNDED_05129 1123070.KB899251_gene671 7.8e-93 348.2 Verrucomicrobiae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2ITJE@203494,46SEZ@74201,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain JOKFNDED_05130 1156937.MFUM_970015 1.9e-35 154.8 unclassified Verrucomicrobia atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 Bacteria 37FV6@326457,46SCC@74201,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits JOKFNDED_05131 1396418.BATQ01000182_gene857 3e-26 124.8 Verrucomicrobiae atpC ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2IUNC@203494,46T0F@74201,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane JOKFNDED_05132 1123070.KB899248_gene116 7.6e-36 158.7 Verrucomicrobiae Bacteria 2ITZE@203494,46SPP@74201,COG0591@1,COG0591@2 NA|NA|NA E Sodium:solute symporter family JOKFNDED_05133 1396141.BATP01000060_gene4641 2.9e-93 349.4 Verrucomicrobiae dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2ITNP@203494,46S6H@74201,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids JOKFNDED_05134 1396141.BATP01000060_gene4642 1.9e-118 432.6 Verrucomicrobiae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2ITMH@203494,46SPK@74201,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria JOKFNDED_05135 1396141.BATP01000062_gene4452 1.9e-59 235.7 Verrucomicrobiae hisH ko:K01663,ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2IUAC@203494,46V4G@74201,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR JOKFNDED_05136 1403819.BATR01000126_gene4519 1.5e-69 269.2 Verrucomicrobiae hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 2IU4M@203494,46SR2@74201,COG0131@1,COG0131@2 NA|NA|NA E Imidazoleglycerol-phosphate dehydratase JOKFNDED_05137 1403819.BATR01000168_gene5758 6.1e-09 70.1 Verrucomicrobiae ko:K07126 ko00000 Bacteria 2IUT4@203494,46SWR@74201,COG0790@1,COG0790@2 NA|NA|NA S Sel1-like repeats. JOKFNDED_05138 1403819.BATR01000176_gene5944 2.6e-61 242.7 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_05139 1121904.ARBP01000006_gene3699 1.3e-29 136.0 Cytophagia 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47YPG@768503,4PM6P@976,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_05140 1396141.BATP01000045_gene1811 3.4e-209 734.6 Verrucomicrobiae MA20_16195 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0030115,GO:0030312,GO:0044464,GO:0045229,GO:0071840,GO:0071944 Bacteria 2ITXX@203494,46TDM@74201,COG1305@1,COG1305@2,COG4196@1,COG4196@2 NA|NA|NA E Putative amidoligase enzyme (DUF2126) JOKFNDED_05141 1396141.BATP01000047_gene3900 6.4e-130 471.9 Verrucomicrobiae MA20_16190 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IU1D@203494,46TPA@74201,COG2307@1,COG2307@2,COG2308@1,COG2308@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. JOKFNDED_05142 765913.ThidrDRAFT_1685 2.9e-69 268.9 Chromatiales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MVMI@1224,1RNV8@1236,1WWYH@135613,COG1305@1,COG1305@2 NA|NA|NA E Bacterial transglutaminase-like N-terminal JOKFNDED_05143 1123242.JH636434_gene5043 7.5e-81 308.1 Planctomycetes Bacteria 2EXMI@1,2J1TH@203682,33QXD@2 NA|NA|NA S Concanavalin A-like lectin/glucanases superfamily JOKFNDED_05144 886293.Sinac_3465 7.8e-133 480.7 Planctomycetes Bacteria 2IXDY@203682,COG3356@1,COG3356@2 NA|NA|NA G lyase activity JOKFNDED_05145 497964.CfE428DRAFT_6006 2.7e-86 325.5 Verrucomicrobia Bacteria 46TKX@74201,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold JOKFNDED_05146 595460.RRSWK_05060 4.2e-106 391.7 Planctomycetes Bacteria 2IYEA@203682,COG1520@1,COG1520@2 NA|NA|NA S PQQ-like domain JOKFNDED_05147 1123242.JH636435_gene769 2.4e-51 209.5 Planctomycetes Bacteria 2DBNR@1,2IYX9@203682,2ZA54@2 NA|NA|NA S Methane oxygenase PmoA JOKFNDED_05148 1123508.JH636443_gene4666 2.3e-42 179.1 Planctomycetes Bacteria 28NEV@1,2J3N7@203682,30U5P@2 NA|NA|NA JOKFNDED_05149 497964.CfE428DRAFT_6043 1.3e-123 449.9 Verrucomicrobia Bacteria 28N13@1,2ZB7C@2,46UA3@74201 NA|NA|NA S Right handed beta helix region JOKFNDED_05150 497964.CfE428DRAFT_5269 8.3e-33 147.1 Verrucomicrobia Bacteria 46T0I@74201,COG1363@1,COG1363@2 NA|NA|NA G M42 glutamyl aminopeptidase JOKFNDED_05151 243090.RB7028 6e-208 730.3 Planctomycetes Bacteria 2J16U@203682,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_05152 1519464.HY22_11920 2e-51 210.3 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_05153 1519464.HY22_11920 1.2e-59 237.7 Bacteria ko:K20276,ko:K21449 ko02024,map02024 ko00000,ko00001,ko02000 1.B.40.2 Bacteria COG3391@1,COG3391@2,COG4412@1,COG4412@2 NA|NA|NA S peptidase activity, acting on L-amino acid peptides JOKFNDED_05154 349741.Amuc_1423 2e-45 190.3 Verrucomicrobiae Bacteria 2EZMG@1,2IU6Q@203494,33SSM@2,46UUT@74201 NA|NA|NA JOKFNDED_05155 1123248.KB893381_gene1089 1.5e-40 174.1 Sphingobacteriia ko:K02396,ko:K14274 ko00040,ko02040,map00040,map02040 R02427 RC00713 ko00000,ko00001,ko01000,ko02035 Bacteria 1IX26@117747,4NK33@976,COG1345@1,COG1345@2,COG2931@1,COG2931@2,COG3055@1,COG3055@2,COG3386@1,COG3386@2 NA|NA|NA G domain, Protein JOKFNDED_05156 1278971.AOGF01000025_gene2002 5.9e-07 60.5 Pasteurellales Bacteria 1QI1H@1224,1TFUC@1236,1YA7Y@135625,2AUJ3@1,31K7M@2 NA|NA|NA JOKFNDED_05160 240016.ABIZ01000001_gene1288 2.9e-57 228.0 Verrucomicrobia Bacteria 46V2V@74201,COG0662@1,COG0662@2 NA|NA|NA G Cupin domain JOKFNDED_05161 864702.OsccyDRAFT_2607 3.4e-27 128.3 Oscillatoriales Bacteria 1G7KC@1117,1HHFW@1150,COG2405@1,COG2405@2 NA|NA|NA S Domain of unknown function (DUF3368) JOKFNDED_05162 278963.ATWD01000001_gene2662 6.7e-16 90.1 Bacteria Bacteria COG2886@1,COG2886@2 NA|NA|NA E Uncharacterised protein family (UPF0175) JOKFNDED_05163 278957.ABEA03000182_gene1980 6.2e-108 397.9 Verrucomicrobia Bacteria 28HUC@1,2Z811@2,46TJ5@74201 NA|NA|NA JOKFNDED_05164 452637.Oter_0633 1.2e-154 553.1 Opitutae fumC 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 3K7NN@414999,46SFC@74201,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate JOKFNDED_05165 637390.AFOH01000122_gene437 2.5e-42 178.7 Acidithiobacillales Bacteria 1RCZE@1224,1S52X@1236,2NCNI@225057,COG1569@1,COG1569@2 NA|NA|NA S PIN domain JOKFNDED_05166 751945.Theos_1179 2.9e-17 95.1 Deinococcus-Thermus Bacteria 1WKDU@1297,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain JOKFNDED_05168 96561.Dole_1840 8.4e-21 106.7 Bacteria ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_05169 177437.HRM2_06590 1.5e-07 63.2 Desulfobacterales 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1PRVB@1224,2MP3U@213118,2X518@28221,431RA@68525,COG0399@1,COG0399@2 NA|NA|NA M UDP-4-amino-4-deoxy-L-arabinose aminotransferase JOKFNDED_05170 41431.PCC8801_4303 1.1e-13 82.4 Cyanothece Bacteria 1GH4S@1117,2B7MA@1,320SE@2,3KIW8@43988 NA|NA|NA S Domain of unknown function (DUF4926) JOKFNDED_05171 1122176.KB903532_gene2517 0.0 1247.6 Sphingobacteriia fdsA 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 Bacteria 1IX2V@117747,4PKV4@976,COG3383@1,COG3383@2 NA|NA|NA C TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type JOKFNDED_05172 760192.Halhy_5328 1.2e-43 182.6 Sphingobacteriia fdsB 1.6.5.3 ko:K00124,ko:K00127,ko:K00334,ko:K00335 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1INS2@117747,4NFB5@976,COG1894@1,COG1894@2,COG1905@1,COG1905@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain JOKFNDED_05173 240016.ABIZ01000001_gene123 3e-53 216.5 Bacteria Bacteria COG1075@1,COG1075@2 NA|NA|NA KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold JOKFNDED_05174 1403819.BATR01000094_gene2954 3.1e-75 289.3 Verrucomicrobiae Bacteria 2IWH3@203494,46VIN@74201,COG0811@1,COG0811@2 NA|NA|NA U MotA/TolQ/ExbB proton channel family JOKFNDED_05175 344747.PM8797T_19101 1.2e-16 94.0 Planctomycetes Bacteria 2ENWP@1,2J3DB@203682,33GHM@2 NA|NA|NA JOKFNDED_05176 1403819.BATR01000094_gene2956 1.2e-15 91.7 Bacteria Bacteria 2EEMD@1,338FA@2 NA|NA|NA JOKFNDED_05177 344747.PM8797T_07699 5.2e-105 387.9 Planctomycetes Bacteria 2IWSK@203682,COG2755@1,COG2755@2 NA|NA|NA E N-terminus of Esterase_SGNH_hydro-type JOKFNDED_05178 240016.ABIZ01000001_gene2833 7.9e-116 423.7 Verrucomicrobiae yqfA Bacteria 2ITH8@203494,46TWZ@74201,COG4864@1,COG4864@2 NA|NA|NA S SigmaW regulon antibacterial JOKFNDED_05180 1396418.BATQ01000171_gene2912 2.5e-76 292.7 Verrucomicrobiae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IVW0@203494,46TM1@74201,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain JOKFNDED_05181 290400.Jann_3107 4.8e-53 214.5 Alphaproteobacteria ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1RA1K@1224,2U7CA@28211,COG1136@1,COG1136@2 NA|NA|NA V COG1136 ABC-type antimicrobial peptide transport system ATPase component JOKFNDED_05182 1123070.KB899247_gene1446 8.4e-33 148.3 Verrucomicrobiae Bacteria 2ECB1@1,2IW2Q@203494,3369C@2,46WPZ@74201 NA|NA|NA JOKFNDED_05185 1403819.BATR01000191_gene6559 0.0 1086.2 Verrucomicrobiae rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2ITJQ@203494,46S8Q@74201,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates JOKFNDED_05186 497964.CfE428DRAFT_5517 1.5e-67 263.5 Verrucomicrobia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 46VAM@74201,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 JOKFNDED_05188 1403819.BATR01000053_gene1609 4.9e-105 388.3 Verrucomicrobiae ko:K01138 ko00000,ko01000 Bacteria 2IUAA@203494,46TNU@74201,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase JOKFNDED_05190 1536775.H70737_12750 2e-25 122.1 Paenibacillaceae blaI ko:K02171 ko01501,map01501 M00627 ko00000,ko00001,ko00002,ko01504,ko03000 Bacteria 1V7EY@1239,26YMQ@186822,4HIKG@91061,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor JOKFNDED_05191 1396418.BATQ01000041_gene6377 2.5e-47 195.7 Bacteria Bacteria COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) JOKFNDED_05193 344747.PM8797T_20783 2.1e-49 202.6 Planctomycetes 5.1.3.22,5.3.1.5 ko:K01805,ko:K03079 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R00878,R01432,R03244 RC00376,RC00516,RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2IXXX@203682,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel JOKFNDED_05194 1403819.BATR01000102_gene3389 1.3e-255 889.0 Verrucomicrobiae ko:K02305,ko:K08738 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 Bacteria 2IU00@203494,46TYQ@74201,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3474@1,COG3474@2,COG3828@1,COG3828@2 NA|NA|NA CG Cytochrome c JOKFNDED_05196 794903.OPIT5_06700 1.8e-18 99.0 Verrucomicrobia Bacteria 46WDF@74201,COG1848@1,COG1848@2 NA|NA|NA S PIN domain JOKFNDED_05197 1484460.JSWG01000015_gene1026 2.9e-18 100.1 Bacteroidetes 4.2.2.3 ko:K01729,ko:K12287 ko00051,map00051 R03706 ko00000,ko00001,ko01000,ko02044 Bacteria 4NMB8@976,COG1345@1,COG1345@2,COG1361@1,COG1361@2,COG3227@1,COG3227@2,COG3420@1,COG3420@2,COG3897@1,COG3897@2 NA|NA|NA M Conserved repeat domain JOKFNDED_05198 1163409.UUA_09246 3.9e-30 139.4 Proteobacteria Bacteria 1NZNX@1224,2EHAS@1,33B2M@2 NA|NA|NA JOKFNDED_05201 448385.sce7607 9.6e-42 177.9 Proteobacteria Bacteria 1N8CV@1224,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain JOKFNDED_05202 1396141.BATP01000057_gene3052 5.3e-32 144.4 Verrucomicrobiae 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 2IV4J@203494,46UEG@74201,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Glucose / Sorbosone dehydrogenase JOKFNDED_05204 1210884.HG799468_gene13603 4.8e-122 445.7 Planctomycetes Bacteria 2IXDW@203682,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C JOKFNDED_05205 243090.RB2848 4.4e-106 391.7 Planctomycetes Bacteria 2J4ZE@203682,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) JOKFNDED_05206 118168.MC7420_990 8.3e-19 101.7 Oscillatoriales Bacteria 1GCVA@1117,1HF4Y@1150,COG1106@1,COG1106@2 NA|NA|NA S AAA ATPase domain JOKFNDED_05207 1396141.BATP01000004_gene5905 5.9e-75 288.1 Verrucomicrobiae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 2IU4J@203494,46U1R@74201,COG1929@1,COG1929@2 NA|NA|NA G Glycerate kinase family JOKFNDED_05208 497964.CfE428DRAFT_3542 2.3e-106 392.1 Verrucomicrobia cfr9IM 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 ko00000,ko01000,ko02048 Bacteria 46TXQ@74201,COG0863@1,COG0863@2,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase JOKFNDED_05209 344747.PM8797T_24606 3.4e-98 365.2 Planctomycetes ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2IZC9@203682,COG1879@1,COG1879@2 NA|NA|NA G ABC-type sugar transport system, periplasmic JOKFNDED_05210 1396141.BATP01000026_gene1041 1.6e-26 125.2 Verrucomicrobiae phhB 3.5.4.33,4.2.1.96 ko:K01724,ko:K11991 ko00790,map00790 R04734,R10223 RC00477,RC01208 ko00000,ko00001,ko01000,ko03016,ko04147 Bacteria 2IV0Z@203494,46TB8@74201,COG2154@1,COG2154@2 NA|NA|NA H Pterin 4 alpha carbinolamine dehydratase JOKFNDED_05211 1396418.BATQ01000117_gene4519 4.3e-146 524.2 Verrucomicrobiae cysK 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2IWMW@203494,46W12@74201,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme JOKFNDED_05213 1396418.BATQ01000029_gene5659 6.7e-100 370.5 Verrucomicrobiae nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 Bacteria 2ITSA@203494,46SHQ@74201,COG0029@1,COG0029@2 NA|NA|NA H Fumarate reductase flavoprotein C-term JOKFNDED_05214 1403819.BATR01000085_gene2452 1.1e-75 290.4 Verrucomicrobiae 6.1.1.16 ko:K01884 ko00970,map00970 M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IU5G@203494,46STS@74201,COG3868@1,COG3868@2 NA|NA|NA S Glycoside-hydrolase family GH114 JOKFNDED_05215 240016.ABIZ01000001_gene4767 9.5e-22 110.9 Verrucomicrobia Bacteria 2EMW0@1,33FI8@2,46WXX@74201 NA|NA|NA JOKFNDED_05216 1396141.BATP01000028_gene2290 1e-59 237.3 Verrucomicrobiae 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IU8Y@203494,46SSB@74201,COG1573@1,COG1573@2 NA|NA|NA L Uracil DNA glycosylase superfamily JOKFNDED_05218 1396418.BATQ01000060_gene2055 5e-12 76.3 Verrucomicrobia Bacteria 46UFZ@74201,COG3391@1,COG3391@2 NA|NA|NA S NHL repeat JOKFNDED_05219 344747.PM8797T_06587 1.1e-54 219.5 Planctomycetes bfr GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 2IZCD@203682,COG2193@1,COG2193@2 NA|NA|NA C Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex JOKFNDED_05220 886293.Sinac_4972 1.5e-58 234.2 Planctomycetes 4.6.1.1 ko:K01768,ko:K11525 ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02035 Bacteria 2IYZI@203682,COG2114@1,COG2114@2,COG2203@1,COG2203@2 NA|NA|NA T Adenylyl- / guanylyl cyclase, catalytic domain JOKFNDED_05221 388413.ALPR1_04868 3.2e-26 125.2 Cytophagia paiA Bacteria 47QAW@768503,4NQVT@976,COG0454@1,COG0456@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase JOKFNDED_05222 382464.ABSI01000013_gene1630 3.5e-127 462.2 Verrucomicrobia phoU_1 ko:K03324 ko00000,ko02000 2.A.58.2 Bacteria 46SD7@74201,COG1283@1,COG1283@2 NA|NA|NA P Na+/Pi-cotransporter JOKFNDED_05223 449447.MAE_14960 5.9e-119 434.5 Cyanobacteria fabF 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iSB619.SA_RS04785 Bacteria 1G1J5@1117,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP JOKFNDED_05224 1396418.BATQ01000056_gene252 1.3e-148 533.5 Verrucomicrobiae msbA ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2ITX3@203494,46S6K@74201,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region JOKFNDED_05225 530564.Psta_1971 6.8e-52 210.7 Planctomycetes fklB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042597,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564 5.2.1.8 ko:K03773 ko00000,ko01000,ko03110 Bacteria 2IZDZ@203682,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans JOKFNDED_05226 1396141.BATP01000007_gene5542 6.2e-21 107.1 Verrucomicrobiae prfA3 Bacteria 2IUUG@203494,46T84@74201,COG1186@1,COG1186@2 NA|NA|NA J RF-1 domain JOKFNDED_05227 595536.ADVE02000001_gene199 1.9e-55 222.6 Methylocystaceae Bacteria 1QW4Z@1224,2U65C@28211,36ZBZ@31993,COG2890@1,COG2890@2 NA|NA|NA J Methyltransferase domain JOKFNDED_05228 1396141.BATP01000058_gene1972 8.4e-72 276.9 Bacteria Bacteria COG4221@1,COG4221@2 NA|NA|NA IQ oxidoreductase activity JOKFNDED_05229 1396141.BATP01000003_gene5136 4.2e-141 508.4 Verrucomicrobiae parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2ITPU@203494,46TWK@74201,COG0188@1,COG0188@2 NA|NA|NA L DNA Topoisomerase IV JOKFNDED_05230 700598.Niako_7114 3.3e-97 361.7 Sphingobacteriia corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1IQ7A@117747,4NG3C@976,COG0598@1,COG0598@2 NA|NA|NA P PFAM CorA-like Mg2 transporter protein JOKFNDED_05231 794903.OPIT5_29980 1.4e-07 63.9 Verrucomicrobia Bacteria 2EX0Y@1,33QC4@2,46UUA@74201 NA|NA|NA JOKFNDED_05232 994479.GL877879_gene4259 2e-13 84.0 Pseudonocardiales 3.6.4.12 ko:K02314,ko:K17680 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03029,ko03032 Bacteria 2I62I@201174,4E8JS@85010,COG0305@1,COG0305@2 NA|NA|NA L Protein of unknown function (DUF3987) JOKFNDED_05234 1396141.BATP01000001_gene5376 6.1e-35 154.1 Verrucomicrobiae Bacteria 2FDAI@1,2IVX3@203494,345CE@2,46WE8@74201 NA|NA|NA JOKFNDED_05235 240016.ABIZ01000001_gene3397 1.1e-57 230.3 Verrucomicrobiae ko:K07465 ko00000 Bacteria 2IVVM@203494,46VRY@74201,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily JOKFNDED_05237 240016.ABIZ01000001_gene846 2.1e-07 62.4 Bacteria Bacteria 28S8E@1,2ZEJS@2 NA|NA|NA JOKFNDED_05239 240016.ABIZ01000001_gene5365 9.7e-18 95.9 Verrucomicrobiae Bacteria 2IV7D@203494,46XAN@74201,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_05240 240016.ABIZ01000001_gene5366 1.4e-59 236.5 Bacteria Bacteria COG2520@1,COG2520@2 NA|NA|NA J tRNA (guanine(37)-N(1))-methyltransferase activity JOKFNDED_05241 1173025.GEI7407_2295 5.6e-43 180.6 Oscillatoriales ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1G5U8@1117,1HB72@1150,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphotyrosine protein phosphatase JOKFNDED_05242 794903.OPIT5_23555 1.1e-45 189.5 Opitutae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 3K95G@414999,46YVQ@74201,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase JOKFNDED_05243 1396418.BATQ01000007_gene1397 2.2e-231 808.1 Verrucomicrobiae rtcB 6.5.1.3 ko:K14415 ko00000,ko01000,ko03016 Bacteria 2IUZX@203494,46STD@74201,COG1690@1,COG1690@2 NA|NA|NA S tRNA-splicing ligase RtcB JOKFNDED_05244 1396418.BATQ01000007_gene1396 1.4e-98 366.3 Verrucomicrobiae rtcA GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 ko:K01974 ko00000,ko01000 Bacteria 2IV3E@203494,46UUY@74201,COG0430@1,COG0430@2 NA|NA|NA A RNA 3'-terminal phosphate cyclase (RTC), insert domain JOKFNDED_05246 1123229.AUBC01000012_gene2822 1.1e-08 67.0 Alphaproteobacteria Bacteria 1R7AU@1224,2DZ9M@1,2TUDM@28211,32V6Z@2 NA|NA|NA JOKFNDED_05247 384765.SIAM614_02416 4.5e-53 215.3 Alphaproteobacteria 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1R70M@1224,2TY9N@28211,COG0189@1,COG0189@2 NA|NA|NA HJ ligase activity JOKFNDED_05248 1122919.KB905630_gene6 8.9e-63 247.7 Paenibacillaceae Bacteria 1VCSB@1239,26QC5@186822,4HCD3@91061,COG0189@1,COG0189@2 NA|NA|NA HJ ligase activity JOKFNDED_05249 331113.SNE_A11690 2.1e-53 216.9 Bacteria cbcK 2.1.1.80,3.1.1.61,4.6.1.1 ko:K01768,ko:K13924 ko00230,ko02020,ko02025,ko02030,ko04113,ko04213,map00230,map02020,map02025,map02030,map04113,map04213 M00506,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria COG2114@1,COG2114@2,COG2770@1,COG2770@2,COG3290@1,COG3290@2 NA|NA|NA T Histidine kinase JOKFNDED_05250 243231.GSU1342 6.6e-45 188.0 Deltaproteobacteria Bacteria 1MXRP@1224,2WV7E@28221,4302B@68525,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain JOKFNDED_05251 240016.ABIZ01000001_gene551 4.3e-83 314.7 Verrucomicrobiae yhhW ko:K06911 ko00000 Bacteria 2IU6M@203494,46SRJ@74201,COG1741@1,COG1741@2 NA|NA|NA S Pirin JOKFNDED_05252 1403819.BATR01000124_gene4371 3.1e-20 104.8 Verrucomicrobiae Bacteria 2DMEF@1,2IWHC@203494,32QYK@2,46W6R@74201 NA|NA|NA JOKFNDED_05253 522306.CAP2UW1_2492 1.2e-149 536.2 unclassified Betaproteobacteria ko:K10680 ko00633,ko01120,map00633,map01120 R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 Bacteria 1KQ64@119066,1MVIX@1224,2VH2S@28216,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family JOKFNDED_05254 344747.PM8797T_00654 5.3e-164 584.3 Planctomycetes Bacteria 2IZUB@203682,COG2072@1,COG2072@2 NA|NA|NA P FAD dependent oxidoreductase JOKFNDED_05255 1123242.JH636434_gene3211 3.1e-39 168.3 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J3C7@203682,COG1595@1,COG1595@2 NA|NA|NA K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog JOKFNDED_05256 344747.PM8797T_24651 8e-102 377.9 Planctomycetes Bacteria 2IYIE@203682,COG3712@1,COG3712@2 NA|NA|NA PT Concanavalin A-like lectin/glucanases superfamily JOKFNDED_05257 240016.ABIZ01000001_gene4459 1.2e-146 526.9 Verrucomicrobia murQ GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8,4.2.1.126 ko:K07106,ko:K18676 ko00520,ko01100,map00520,map01100 R01961,R08555 RC00002,RC00017,RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 46SJI@74201,COG2103@1,COG2103@2,COG2971@1,COG2971@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate JOKFNDED_05258 240016.ABIZ01000001_gene5490 1.4e-60 240.4 Verrucomicrobiae Bacteria 2IVMQ@203494,46V7I@74201,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like JOKFNDED_05259 382464.ABSI01000010_gene3240 2.5e-51 208.4 Verrucomicrobiae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 2IUG9@203494,46SRV@74201,COG0041@1,COG0041@2 NA|NA|NA F AIR carboxylase JOKFNDED_05260 1396141.BATP01000035_gene4096 3.5e-115 421.8 Verrucomicrobiae purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 2ITZP@203494,46SG7@74201,COG0026@1,COG0026@2 NA|NA|NA F ATP-grasp domain JOKFNDED_05261 388467.A19Y_1682 5.4e-16 89.7 Oscillatoriales Bacteria 1G9Q4@1117,1HCRN@1150,2DP6Q@1,330SE@2 NA|NA|NA JOKFNDED_05262 316055.RPE_2423 3e-27 127.5 Bradyrhizobiaceae Bacteria 1N7X1@1224,2E46S@1,2UUK2@28211,32Z2Q@2,3K4S1@41294 NA|NA|NA S manually curated JOKFNDED_05263 240016.ABIZ01000001_gene3823 4.4e-144 517.7 Verrucomicrobiae nagZ GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 2.7.8.7,3.2.1.21,3.2.1.52 ko:K00997,ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00770,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00770,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R01625,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00002,RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 GH3 iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790 Bacteria 2ITMC@203494,46S5G@74201,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain JOKFNDED_05264 1121012.AUKX01000021_gene1671 3.8e-54 219.2 Flavobacteriia murI 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1I0TG@117743,4NIZ7@976,COG0796@1,COG0796@2 NA|NA|NA M Asp/Glu/Hydantoin racemase JOKFNDED_05265 1123248.KB893381_gene986 2.8e-90 339.0 Sphingobacteriia Bacteria 1IU11@117747,4NWMR@976,COG1073@1,COG1073@2 NA|NA|NA S Acetyl xylan esterase (AXE1) JOKFNDED_05266 1396141.BATP01000001_gene5392 3.4e-213 748.0 Verrucomicrobiae aspA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222 Bacteria 2IV1X@203494,46U0V@74201,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus JOKFNDED_05267 240016.ABIZ01000001_gene125 2.1e-52 213.4 Bacteria ko:K06076 ko00000,ko02000 1.B.9 Bacteria COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transporting porin activity JOKFNDED_05268 1123242.JH636438_gene5840 1.3e-90 339.7 Bacteria Bacteria 2BWKA@1,32QZQ@2 NA|NA|NA S Concanavalin A-like lectin/glucanases superfamily JOKFNDED_05269 1396141.BATP01000003_gene5194 3.4e-82 311.6 Verrucomicrobia ko:K07010 ko00000,ko01002 Bacteria 46WYH@74201,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 JOKFNDED_05270 1403819.BATR01000092_gene2763 1e-123 450.3 Verrucomicrobiae dgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 2ITWR@203494,46UHP@74201,COG0232@1,COG0232@2 NA|NA|NA F Phosphohydrolase-associated domain JOKFNDED_05271 1123070.KB899247_gene1537 6.2e-75 288.9 Verrucomicrobiae Bacteria 2ITZK@203494,46TX9@74201,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase JOKFNDED_05273 1396141.BATP01000060_gene4625 7.7e-134 483.8 Verrucomicrobiae rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2ITQU@203494,46TUA@74201,COG0513@1,COG0513@2 NA|NA|NA L helicase superfamily c-terminal domain JOKFNDED_05274 530564.Psta_0196 2e-96 359.0 Planctomycetes 5.1.3.30,5.1.3.31 ko:K18910 R10817,R10818 RC03111,RC03283 ko00000,ko01000 Bacteria 2IXNX@203682,COG1082@1,COG1082@2 NA|NA|NA G COG1082 Sugar phosphate JOKFNDED_05276 1270196.JCKI01000008_gene1565 1.3e-24 119.4 Sphingobacteriia Bacteria 1IY9R@117747,4NUB6@976,COG3744@1,COG3744@2 NA|NA|NA S PIN domain JOKFNDED_05279 1403819.BATR01000051_gene1526 2.5e-202 711.8 Verrucomicrobiae gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 2ITW5@203494,46YYU@74201,COG2804@1,COG2804@2 NA|NA|NA NU Type II/IV secretion system protein JOKFNDED_05280 1396141.BATP01000022_gene436 1.4e-87 330.1 Verrucomicrobiae pilC2 ko:K02653 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 2IV7F@203494,46YT3@74201,COG1459@1,COG1459@2 NA|NA|NA NU Type II secretion system (T2SS), protein F JOKFNDED_05281 595460.RRSWK_04473 2.6e-161 575.1 Planctomycetes neu 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2IYPT@203682,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_05282 864702.OsccyDRAFT_3183 2.7e-109 402.9 Oscillatoriales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1G0JG@1117,1HADF@1150,COG2931@1,COG2931@2,COG5434@1,COG5434@2 NA|NA|NA M Pectate lyase superfamily protein JOKFNDED_05283 794903.OPIT5_12995 4.4e-13 83.2 Verrucomicrobia Bacteria 46Z9C@74201,COG3534@1,COG3534@2 NA|NA|NA G alpha-L-arabinofuranosidase JOKFNDED_05284 240016.ABIZ01000001_gene5896 1.3e-64 254.2 Verrucomicrobia Bacteria 46TN1@74201,COG3064@1,COG3064@2 NA|NA|NA M Membrane JOKFNDED_05285 1403819.BATR01000039_gene1151 1e-158 566.6 Verrucomicrobia Bacteria 46U3G@74201,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_05286 857087.Metme_2094 1.3e-143 517.3 Gammaproteobacteria Otg1 Bacteria 1N08V@1224,1RNGS@1236,COG5373@1,COG5373@2 NA|NA|NA S Membrane JOKFNDED_05288 1122970.AUHC01000022_gene2490 3.9e-42 177.9 Sphingomonadales Bacteria 1RHV9@1224,2KETY@204457,2TXF0@28211,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain JOKFNDED_05289 883.DvMF_2145 9.5e-08 62.8 Deltaproteobacteria Bacteria 1N7K8@1224,2WXDZ@28221,432TR@68525,COG4453@1,COG4453@2 NA|NA|NA S Protein of unknown function (DUF1778) JOKFNDED_05290 1396141.BATP01000003_gene5191 0.0 1689.9 Verrucomicrobiae pyc GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18410 Bacteria 2IU6I@203494,46S8N@74201,COG1038@1,COG1038@2 NA|NA|NA C Conserved carboxylase domain JOKFNDED_05291 1123508.JH636439_gene906 1.4e-115 423.3 Bacteria Bacteria COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase activity JOKFNDED_05292 1300345.LF41_717 7e-31 141.0 Xanthomonadales Bacteria 1QCQH@1224,1T8GE@1236,1XAMR@135614,2AQ4A@1,31F9J@2 NA|NA|NA JOKFNDED_05293 1461694.ATO9_09390 2.3e-41 176.0 Alphaproteobacteria ko:K07052 ko00000 Bacteria 1NKQV@1224,2UKFC@28211,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity JOKFNDED_05294 329726.AM1_5239 4.6e-30 138.7 Bacteria sodC 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Bacteria COG2032@1,COG2032@2 NA|NA|NA P superoxide dismutase activity JOKFNDED_05295 583355.Caka_1395 2.1e-14 84.7 Bacteria Bacteria 2EIUW@1,33CK7@2 NA|NA|NA JOKFNDED_05296 1396141.BATP01000014_gene2737 1.1e-68 266.9 Verrucomicrobia ko:K07273 ko00000 Bacteria 46WSP@74201,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 JOKFNDED_05297 240016.ABIZ01000001_gene4382 4.2e-76 292.0 Verrucomicrobia Bacteria 2DS81@1,33EXT@2,46VPV@74201 NA|NA|NA JOKFNDED_05300 240016.ABIZ01000001_gene4025 6.4e-27 127.1 Bacteria vapC ko:K07062 ko00000,ko01000,ko02048 Bacteria COG1487@1,COG1487@2 NA|NA|NA S nuclease activity JOKFNDED_05301 497964.CfE428DRAFT_4508 3.1e-23 114.0 Verrucomicrobia Bacteria 2FJ9A@1,34AZB@2,46W48@74201 NA|NA|NA S SpoVT / AbrB like domain JOKFNDED_05307 240016.ABIZ01000001_gene5698 1.6e-167 595.9 Verrucomicrobiae aas 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 Bacteria 2ITYM@203494,46SG3@74201,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme JOKFNDED_05308 1403819.BATR01000164_gene5573 4.2e-30 137.1 Verrucomicrobiae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUPY@203494,46WBX@74201,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome JOKFNDED_05309 1123070.KB899256_gene2227 4.3e-56 224.6 Verrucomicrobiae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IU4A@203494,46SWJ@74201,COG0088@1,COG0088@2 NA|NA|NA J Ribosomal protein L4/L1 family JOKFNDED_05310 349741.Amuc_0304 4.5e-70 271.2 Verrucomicrobiae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IU4D@203494,46SQV@74201,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit JOKFNDED_05311 1396418.BATQ01000058_gene122 1.5e-41 175.3 Verrucomicrobiae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IUCB@203494,46SVV@74201,COG0051@1,COG0051@2 NA|NA|NA J Ribosomal protein S10p/S20e JOKFNDED_05312 1403819.BATR01000164_gene5577 7.1e-165 587.0 Verrucomicrobiae fusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2ITYS@203494,46SFV@74201,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome JOKFNDED_05313 626887.J057_03500 1.5e-40 172.6 Alteromonadaceae IV02_26610 Bacteria 1RGX8@1224,1S5YR@1236,467C1@72275,COG4067@1,COG4067@2 NA|NA|NA O protein conserved in archaea JOKFNDED_05314 234267.Acid_5864 2.2e-38 166.0 Bacteria Bacteria COG1082@1,COG1082@2 NA|NA|NA G myo-inosose-2 dehydratase activity JOKFNDED_05315 1122605.KB893637_gene3269 1.6e-78 301.2 Bacteria 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria COG4692@1,COG4692@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_05316 243090.RB3849 4.5e-194 684.5 Planctomycetes 3.1.6.12 ko:K01135,ko:K01138 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 ko00000,ko00001,ko00002,ko01000 Bacteria 2IYMC@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A JOKFNDED_05317 595460.RRSWK_06561 4.4e-192 677.9 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_05318 1396418.BATQ01000079_gene793 7.1e-179 634.0 Verrucomicrobia Bacteria 46TNI@74201,COG0613@1,COG0613@2 NA|NA|NA S PHP domain protein JOKFNDED_05319 583355.Caka_1724 9.1e-72 276.9 Opitutae arnC 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 3K9NN@414999,46VFD@74201,COG0463@1,COG0463@2 NA|NA|NA M PFAM glycosyl transferase family 2 JOKFNDED_05320 1396418.BATQ01000099_gene5540 1.9e-28 134.0 Verrucomicrobia enpP 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 46US5@74201,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase JOKFNDED_05321 1396418.BATQ01000030_gene5614 1.7e-20 104.8 Verrucomicrobiae macB_1 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IWMB@203494,46TQS@74201,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain JOKFNDED_05323 344747.PM8797T_24596 2.3e-91 342.4 Planctomycetes ko:K10440 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2IZ57@203682,COG1172@1,COG1172@2 NA|NA|NA P COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components JOKFNDED_05324 595460.RRSWK_06070 1.3e-103 383.6 Planctomycetes Bacteria 2IXJ0@203682,COG0673@1,COG0673@2 NA|NA|NA S and related JOKFNDED_05325 439235.Dalk_1463 2.8e-57 229.2 Desulfobacterales ko:K07494,ko:K07499 ko00000 Bacteria 1RJT0@1224,2MPB2@213118,2X7ZB@28221,43CRQ@68525,COG3335@1,COG3335@2,COG3415@1,COG3415@2 NA|NA|NA L DDE superfamily endonuclease JOKFNDED_05326 1396418.BATQ01000151_gene2321 4.9e-40 171.8 Verrucomicrobiae Bacteria 2IWNX@203494,46Z2S@74201,COG4122@1,COG4122@2 NA|NA|NA S Methyltransferase FkbM domain JOKFNDED_05327 1156937.MFUM_290017 1.4e-22 112.5 unclassified Verrucomicrobia infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 37H0F@326457,46T5J@74201,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex JOKFNDED_05328 1396141.BATP01000058_gene1947 1.2e-09 70.1 Verrucomicrobiae Bacteria 2FHXR@1,2IV0P@203494,349QR@2,46WDM@74201 NA|NA|NA S DnaJ molecular chaperone homology domain JOKFNDED_05329 1396141.BATP01000039_gene1376 6.1e-167 594.3 Verrucomicrobiae hscA GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010467,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051604,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0097428,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1903506,GO:1990230,GO:1990234,GO:2001141 ko:K04043,ko:K04044 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33,1.A.33.1 Bacteria 2IU3D@203494,46TYN@74201,COG0443@1,COG0443@2 NA|NA|NA O MreB/Mbl protein JOKFNDED_05330 322710.Avin_29500 4.7e-84 318.5 Gammaproteobacteria lolE_2 ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 1R4Q2@1224,1RZZ8@1236,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component JOKFNDED_05331 1038869.AXAN01000048_gene4531 4.2e-26 125.2 Burkholderiaceae Bacteria 1KIRC@119060,1RE9C@1224,2VSUX@28216,COG2834@1,COG2834@2 NA|NA|NA M Outer membrane lipoprotein-sorting protein JOKFNDED_05332 649639.Bcell_1278 1.5e-80 307.0 Bacillus Bacteria 1TQS9@1239,1ZBDC@1386,4HDHW@91061,COG0624@1,COG0624@2 NA|NA|NA E Acetylornithine deacetylase JOKFNDED_05333 243090.RB9860 1.6e-69 269.6 Planctomycetes ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 2IZD1@203682,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase JOKFNDED_05334 1123070.KB899247_gene1597 2.2e-28 132.1 Verrucomicrobiae Bacteria 2BKT6@1,2IWCU@203494,32F9D@2,46XQ4@74201 NA|NA|NA JOKFNDED_05336 1403819.BATR01000031_gene991 2.5e-94 353.2 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process JOKFNDED_05338 1405.DJ92_2955 1.2e-153 550.1 Bacillus Bacteria 1USD9@1239,1ZDCF@1386,4HAYV@91061,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily JOKFNDED_05339 1123070.KB899250_gene558 4.5e-56 224.2 Verrucomicrobiae 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 2IWQI@203494,46V63@74201,COG1225@1,COG1225@2 NA|NA|NA O Redoxin JOKFNDED_05341 1183438.GKIL_3983 7e-97 360.9 Bacteria Bacteria COG0665@1,COG0665@2 NA|NA|NA E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity JOKFNDED_05343 575540.Isop_0292 6.4e-126 458.8 Planctomycetes ko:K09992 ko00000 Bacteria 2IWYB@203682,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C heme-binding domain, Pirellula Verrucomicrobium type JOKFNDED_05344 864702.OsccyDRAFT_2608 2.9e-14 84.3 Oscillatoriales Bacteria 1G8A1@1117,1HCZ7@1150,COG2886@1,COG2886@2 NA|NA|NA S Uncharacterised protein family (UPF0175) JOKFNDED_05345 278963.ATWD01000001_gene2663 4e-28 131.3 Acidobacteriia Bacteria 2JNS5@204432,3Y95W@57723,COG2405@1,COG2405@2 NA|NA|NA JOKFNDED_05346 1403819.BATR01000187_gene6437 9.5e-53 213.0 Verrucomicrobia gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 iNJ661.Rv1826 Bacteria 46WCE@74201,COG0509@1,COG0509@2 NA|NA|NA E Glycine cleavage H-protein JOKFNDED_05347 497964.CfE428DRAFT_2670 5.9e-47 194.5 Verrucomicrobia 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 46TVP@74201,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase JOKFNDED_05348 1396418.BATQ01000136_gene3732 4.1e-58 232.3 Verrucomicrobiae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2IU66@203494,46SR0@74201,COG0681@1,COG0681@2 NA|NA|NA U Peptidase S24-like JOKFNDED_05349 349741.Amuc_1036 4.4e-54 217.2 Verrucomicrobiae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2IU2I@203494,46SA7@74201,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner JOKFNDED_05350 1123242.JH636434_gene5593 3.8e-151 541.6 Planctomycetes Bacteria 2IXQS@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_05352 240016.ABIZ01000001_gene3024 1.6e-13 82.8 Verrucomicrobiae Bacteria 2AX49@1,2IWEH@203494,31P2M@2,46XR5@74201 NA|NA|NA JOKFNDED_05353 240016.ABIZ01000001_gene3995 2.3e-95 355.5 Verrucomicrobiae cdsA2 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748,ko:K09949 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 Bacteria 2IU0K@203494,46SJ6@74201,COG3494@1,COG3494@2 NA|NA|NA S Protein of unknown function (DUF1009) JOKFNDED_05354 794903.OPIT5_15030 2e-36 159.8 Verrucomicrobia Bacteria 46SMS@74201,COG0697@1,COG0697@2 NA|NA|NA EG spore germination JOKFNDED_05355 344747.PM8797T_20758 5e-115 421.8 Planctomycetes ko:K03299 ko00000,ko02000 2.A.8 Bacteria 2J1TI@203682,COG2610@1,COG2610@2 NA|NA|NA EG COG2610 H gluconate symporter and related permeases JOKFNDED_05356 1396418.BATQ01000120_gene3046 1.7e-200 705.7 Verrucomicrobiae yidE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07085 ko00000 2.A.81 Bacteria 2IU9A@203494,46YYG@74201,COG2985@1,COG2985@2 NA|NA|NA P Predicted Permease Membrane Region JOKFNDED_05357 69042.WH5701_07536 3.2e-276 957.6 Synechococcus glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 1G0PW@1117,1GZR8@1129,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family JOKFNDED_05358 1489678.RDMS_11685 1.8e-38 166.4 Bacteria yigE Bacteria COG3698@1,COG3698@2 NA|NA|NA S Phosphodiester glycosidase JOKFNDED_05359 862908.BMS_3032 3.7e-35 155.2 Deltaproteobacteria Bacteria 1N1K1@1224,2AFPW@1,2WSXP@28221,315RN@2,42WWK@68525 NA|NA|NA JOKFNDED_05361 1121004.ATVC01000002_gene575 4.9e-56 225.3 Betaproteobacteria 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 1Q1EG@1224,2VMXN@28216,COG4692@1,COG4692@2 NA|NA|NA G BNR repeat-like domain JOKFNDED_05362 1123401.JHYQ01000005_gene284 1.4e-38 166.8 Thiotrichales ddpX 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1RH22@1224,1S2SR@1236,46337@72273,COG3786@1,COG3786@2 NA|NA|NA S protein conserved in bacteria JOKFNDED_05364 411901.BACCAC_03467 6.9e-09 67.4 Bacteroidaceae ybjQ Bacteria 2FT9V@200643,4ARBR@815,4NQGB@976,COG0393@1,COG0393@2 NA|NA|NA S Belongs to the UPF0145 family JOKFNDED_05365 756272.Plabr_4308 1.1e-225 789.6 Planctomycetes Bacteria 2IX9T@203682,COG3119@1,COG3119@2 NA|NA|NA P COG3119 Arylsulfatase A and related enzymes JOKFNDED_05366 1173020.Cha6605_2263 9e-38 163.3 Cyanobacteria Bacteria 1G7GA@1117,COG5654@1,COG5654@2 NA|NA|NA S PFAM RES domain JOKFNDED_05367 1396418.BATQ01000163_gene2017 1.4e-30 139.4 Verrucomicrobiae Bacteria 2IW0M@203494,46XIK@74201,COG5642@1,COG5642@2 NA|NA|NA S Protein of unknown function (DUF2384) JOKFNDED_05371 1396141.BATP01000005_gene6052 3e-35 154.8 Verrucomicrobiae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IU4B@203494,46UCK@74201,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities JOKFNDED_05372 1396141.BATP01000005_gene6053 1.3e-47 197.6 Verrucomicrobiae Bacteria 2IUUX@203494,46VD7@74201,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component JOKFNDED_05373 1396141.BATP01000005_gene6054 3.4e-68 265.4 Verrucomicrobiae Bacteria 2IUE4@203494,46UAR@74201,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 JOKFNDED_05374 1396141.BATP01000005_gene6055 3e-126 459.1 Bacteria Bacteria COG2304@1,COG2304@2 NA|NA|NA IU oxidoreductase activity JOKFNDED_05375 1403819.BATR01000103_gene3462 2.5e-62 245.0 Verrucomicrobiae Bacteria 2IUE2@203494,46SVJ@74201,COG0521@1,COG0521@2 NA|NA|NA H Probable molybdopterin binding domain JOKFNDED_05377 1396418.BATQ01000075_gene662 7.5e-22 109.0 Verrucomicrobiae sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 Bacteria 2ITTQ@203494,46SD3@74201,COG0508@1,COG0508@2 NA|NA|NA C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) JOKFNDED_05378 240016.ABIZ01000001_gene2638 4.2e-266 924.9 Verrucomicrobiae ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2IVES@203494,46V0I@74201,COG1674@1,COG1674@2 NA|NA|NA D FtsK/SpoIIIE family JOKFNDED_05379 925775.XVE_2650 5e-21 107.8 Xanthomonadales Bacteria 1P29Q@1224,1T710@1236,1X8K7@135614,2EHW5@1,33BMQ@2 NA|NA|NA JOKFNDED_05380 349741.Amuc_1126 3.3e-109 402.1 Verrucomicrobiae ksgA 2.1.1.182,5.3.3.2 ko:K01823,ko:K02528 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R10716 RC00003,RC00455,RC03257 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2ITVV@203494,46T1S@74201,COG0030@1,COG0030@2,COG1443@1,COG1443@2 NA|NA|NA IJ Ribosomal RNA adenine dimethylases JOKFNDED_05381 1403819.BATR01000051_gene1492 3.7e-184 651.4 Verrucomicrobiae ywcA ko:K14393 ko00000,ko02000 2.A.21.7 iAF987.Gmet_0739 Bacteria 2IUNV@203494,46UJU@74201,COG4147@1,COG4147@2 NA|NA|NA S Sodium:solute symporter family JOKFNDED_05382 234267.Acid_0924 9.5e-19 99.8 Bacteria Bacteria COG3162@1,COG3162@2 NA|NA|NA S Protein of unknown function, DUF485 JOKFNDED_05383 1396418.BATQ01000136_gene3672 6.6e-217 760.8 Bacteria Bacteria COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c JOKFNDED_05384 521674.Plim_1525 5.4e-209 733.8 Planctomycetes Bacteria 2IXRZ@203682,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) JOKFNDED_05385 1234364.AMSF01000068_gene2137 3.2e-50 205.3 Xanthomonadales YH67_14670 Bacteria 1MWT5@1224,1S5DB@1236,1X4XD@135614,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) JOKFNDED_05387 1266909.AUAG01000018_gene284 3e-43 181.8 Gammaproteobacteria Bacteria 1N1KS@1224,1S4QZ@1236,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease JOKFNDED_05388 1396141.BATP01000047_gene3897 1.8e-126 459.1 Bacteria Bacteria COG5434@1,COG5434@2 NA|NA|NA M polygalacturonase activity JOKFNDED_05391 1396141.BATP01000034_gene4172 1.2e-112 413.3 Verrucomicrobiae desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 2IWNE@203494,46S4J@74201,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase JOKFNDED_05392 158189.SpiBuddy_2901 1.3e-16 93.2 Spirochaetes rbpA Bacteria 2J8UF@203691,COG0724@1,COG0724@2 NA|NA|NA S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JOKFNDED_05393 240016.ABIZ01000001_gene2082 2e-153 549.3 Verrucomicrobiae aldH 1.2.1.26,1.2.1.4 ko:K13877,ko:K14519 ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220 R00264,R05099 RC00080 ko00000,ko00001,ko01000 Bacteria 2IU6F@203494,46SIA@74201,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family JOKFNDED_05394 1403819.BATR01000120_gene4240 8.9e-82 310.5 Verrucomicrobia 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 46UN5@74201,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthetase family JOKFNDED_05395 243090.RB8941 1.9e-172 612.5 Planctomycetes 1.2.1.26 ko:K13877 ko00040,ko00053,map00040,map00053 R00264 RC00080 ko00000,ko00001,ko01000 Bacteria 2IYRE@203682,COG1012@1,COG1012@2 NA|NA|NA C ketoglutarate semialdehyde dehydrogenase JOKFNDED_05396 794903.OPIT5_20115 1.4e-53 216.9 Bacteria Bacteria COG5464@1,COG5464@2 NA|NA|NA S double-stranded DNA endodeoxyribonuclease activity JOKFNDED_05397 530564.Psta_4554 4.5e-62 245.4 Planctomycetes pepQ 3.5.3.3 ko:K08688 ko00260,ko00330,ko01100,map00260,map00330,map01100 R01566 RC00548,RC00549 ko00000,ko00001,ko01000 Bacteria 2IZ0S@203682,COG0006@1,COG0006@2 NA|NA|NA E Xaa-Pro aminopeptidase JOKFNDED_05398 489825.LYNGBM3L_47380 7.4e-169 602.8 Oscillatoriales Bacteria 1G7BP@1117,1HCF5@1150,COG2931@1,COG2931@2,COG3386@1,COG3386@2,COG4447@1,COG4447@2 NA|NA|NA Q Domain of unknown function (DUF4347) JOKFNDED_05399 497964.CfE428DRAFT_2122 1.4e-181 642.9 Bacteria Bacteria COG5434@1,COG5434@2 NA|NA|NA M polygalacturonase activity JOKFNDED_05401 1396418.BATQ01000049_gene373 5e-60 237.3 Verrucomicrobiae Bacteria 2AVVV@1,2IUGY@203494,31MPP@2,46X4F@74201 NA|NA|NA JOKFNDED_05402 1396418.BATQ01000067_gene1666 0.0 1434.1 Verrucomicrobiae czcA ko:K07239,ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1,2.A.6.1.4 Bacteria 2ITM5@203494,46USJ@74201,COG3696@1,COG3696@2 NA|NA|NA P AcrB/AcrD/AcrF family JOKFNDED_05403 240016.ABIZ01000001_gene3911 1.1e-103 383.6 Verrucomicrobiae Bacteria 2ITV5@203494,46YYJ@74201,COG0845@1,COG0845@2 NA|NA|NA M HlyD family secretion protein JOKFNDED_05404 1396418.BATQ01000049_gene370 1.7e-80 306.6 Verrucomicrobiae cecC ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 2IUMA@203494,46X65@74201,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein JOKFNDED_05406 1148.1652268 3.2e-30 138.3 Synechocystis Bacteria 1G51H@1117,1H5QC@1142,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_05407 1396141.BATP01000004_gene5882 5.9e-151 540.8 Verrucomicrobiae chrA ko:K07240 ko00000,ko02000 2.A.51.1 Bacteria 2IUYF@203494,46V8S@74201,COG2059@1,COG2059@2 NA|NA|NA P Chromate transporter JOKFNDED_05408 1234364.AMSF01000010_gene539 1.8e-31 143.3 Bacteria Bacteria 28J5Y@1,2Z91P@2 NA|NA|NA S Methyltransferase domain JOKFNDED_05410 1396418.BATQ01000085_gene1124 4.7e-16 90.1 Verrucomicrobiae Bacteria 2EM29@1,2IWEX@203494,33ERR@2,46WJK@74201 NA|NA|NA JOKFNDED_05411 1396141.BATP01000032_gene4394 2e-275 954.9 Verrucomicrobiae copA Bacteria 2IV7I@203494,46T3J@74201,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase JOKFNDED_05413 314278.NB231_03320 7.2e-147 528.1 Chromatiales Bacteria 1MX2U@1224,1RPD2@1236,1WXID@135613,COG0457@1,COG0457@2 NA|NA|NA S doubled CXXCH JOKFNDED_05415 240016.ABIZ01000001_gene2816 7.8e-58 230.3 Bacteria Bacteria 2F56J@1,33XTA@2 NA|NA|NA JOKFNDED_05416 1396141.BATP01000058_gene1993 1.4e-165 590.5 Verrucomicrobiae Bacteria 2IVDX@203494,46TW3@74201,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase JOKFNDED_05417 1313301.AUGC01000001_gene1514 3.7e-45 188.7 Bacteroidetes Bacteria 4NFSH@976,COG4099@1,COG4099@2 NA|NA|NA E Phospholipase JOKFNDED_05418 1537917.JU82_00065 7e-75 287.7 Epsilonproteobacteria dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1MV9H@1224,2YPJK@29547,42SDU@68525,COG0270@1,COG0270@2 NA|NA|NA H Cytosine-specific methyltransferase JOKFNDED_05420 362663.ECP_4571 5.7e-85 322.8 Gammaproteobacteria 2.7.13.3 ko:K07676 ko02020,ko02026,map02020,map02026 M00474 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1QZD5@1224,1T45M@1236,COG0642@1,COG0642@2,COG1196@1,COG1196@2 NA|NA|NA DT Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JOKFNDED_05422 1123070.KB899263_gene1745 5.4e-162 577.4 Verrucomicrobiae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITXH@203494,46SGJ@74201,COG0151@1,COG0151@2 NA|NA|NA F Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain JOKFNDED_05423 383372.Rcas_2433 1.5e-39 169.5 Chloroflexia pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 2G6WS@200795,375J4@32061,COG2065@1,COG2065@2 NA|NA|NA F Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines JOKFNDED_05424 1396141.BATP01000057_gene3102 1.2e-110 406.4 Verrucomicrobiae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 2ITMZ@203494,46S9E@74201,COG0540@1,COG0540@2 NA|NA|NA F Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain JOKFNDED_05425 1396418.BATQ01000138_gene3913 2.7e-132 478.8 Verrucomicrobiae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 2ITJU@203494,46S78@74201,COG0044@1,COG0044@2 NA|NA|NA F Dihydro-orotase-like JOKFNDED_05427 1459636.NTE_00271 1.1e-07 63.2 Archaea vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Archaea COG1487@1,arCOG02219@2157 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_05429 313628.LNTAR_22164 9.1e-83 313.9 Bacteria 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria COG3540@1,COG3540@2 NA|NA|NA P PhoD-like phosphatase JOKFNDED_05431 1266908.AQPB01000055_gene1961 1.6e-09 69.3 Bacteria vapC ko:K07064 ko00000 Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase JOKFNDED_05432 756272.Plabr_4220 3.3e-52 211.5 Planctomycetes rfaY ko:K03088 ko00000,ko03021 Bacteria 2J2ZA@203682,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase, sigma-24 subunit, ECF subfamily JOKFNDED_05434 937777.Deipe_1185 9.7e-20 102.8 Deinococcus-Thermus Bacteria 1WMFS@1297,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) family JOKFNDED_05435 1396141.BATP01000034_gene4161 1.2e-79 303.5 Verrucomicrobiae dus ko:K05541 ko00000,ko01000,ko03016 Bacteria 2ITU4@203494,46TSS@74201,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines JOKFNDED_05436 583355.Caka_2172 1.5e-59 236.5 Bacteria Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 # 4201 queries scanned # Total time (seconds): 32.9621489048 # Rate: 127.45 q/s