# emapper version: emapper-2.0.1 emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 45 --temp_dir /media/bayegy/disk0/binning_test/Bin_all/emapper//bin.C3.3/_tmp -i /media/bayegy/disk0/binning_test/Bin_all/Bin_prokka//bin.C3.3/bin.C3.3.faa -o /media/bayegy/disk0/binning_test/Bin_all/emapper//bin.C3.3/bin.C3.3 --usemem --override # time: Wed Nov 3 18:00:06 2021 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. HFDCGJPN_00001 1101195.Meth11DRAFT_1641 1.2e-60 239.2 Nitrosomonadales yaiI ko:K09768 ko00000 Bacteria 1RCZA@1224,2KMR2@206350,2VRAZ@28216,COG1671@1,COG1671@2 NA|NA|NA S Uncharacterized BCR, YaiI/YqxD family COG1671 HFDCGJPN_00002 159087.Daro_3556 2.1e-223 781.9 Rhodocyclales kup ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1MUVH@1224,2KUQJ@206389,2VH9I@28216,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell HFDCGJPN_00003 402626.Rpic_3370 2.1e-83 315.5 Burkholderiaceae Bacteria 1K29G@119060,1MWZ5@1224,2VIM1@28216,COG0745@1,COG0745@2 NA|NA|NA KT response regulator HFDCGJPN_00004 159087.Daro_3558 3.1e-119 435.6 Rhodocyclales Bacteria 1MUZQ@1224,2KV3X@206389,2VH62@28216,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor HFDCGJPN_00005 583345.Mmol_1506 8.7e-74 283.1 Nitrosomonadales blc GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 ko:K03098,ko:K07071 ko00000,ko04147 Bacteria 1RDAI@1224,2KMSV@206350,2VRSU@28216,COG3040@1,COG3040@2 NA|NA|NA M Lipocalin / cytosolic fatty-acid binding protein family HFDCGJPN_00006 395961.Cyan7425_0280 1.3e-64 253.4 Cyanothece Bacteria 1G12U@1117,3KJ6J@43988,COG2199@1,COG2199@2,COG2203@1,COG2203@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_00007 666681.M301_1600 5e-82 311.2 Nitrosomonadales 2.3.1.57 ko:K00657,ko:K09973 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1RBFT@1224,2KMCM@206350,2VTX0@28216,COG3735@1,COG3735@2 NA|NA|NA S TraB family HFDCGJPN_00008 582744.Msip34_1117 0.0 1306.2 Nitrosomonadales ygiQ Bacteria 1MUG3@1224,2KMJF@206350,2VJ9A@28216,COG1032@1,COG1032@2 NA|NA|NA C Radical SAM N-terminal HFDCGJPN_00009 582744.Msip34_1111 3e-199 701.8 Betaproteobacteria Bacteria 1NWNJ@1224,2WHI5@28216,COG2199@1,COG2199@2,COG2202@1,COG2202@2 NA|NA|NA T PAS domain containing protein HFDCGJPN_00010 666681.M301_1603 8.1e-220 769.6 Nitrosomonadales copA 1.16.3.3 ko:K22348 ko00000,ko01000 Bacteria 1MU0J@1224,2KMG5@206350,2VM67@28216,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase HFDCGJPN_00011 666681.M301_1604 1.6e-146 526.2 Nitrosomonadales copB ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1MWB0@1224,2KM59@206350,2VIIW@28216,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein HFDCGJPN_00013 582744.Msip34_1110 2.8e-88 331.6 Nitrosomonadales aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 ko:K00684 R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 Bacteria 1R9W8@1224,2KKS8@206350,2VIUV@28216,COG2360@1,COG2360@2 NA|NA|NA O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine HFDCGJPN_00014 265072.Mfla_0931 2.2e-91 342.0 Nitrosomonadales ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 R11547,R11548 RC00064 ko00000,ko01000 Bacteria 1MW62@1224,2KKF8@206350,2VJ8E@28216,COG2935@1,COG2935@2 NA|NA|NA O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate HFDCGJPN_00015 1165096.ARWF01000001_gene638 1.5e-97 362.8 Nitrosomonadales aroA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 1QTZA@1224,2KKEM@206350,2VIS1@28216,COG0287@1,COG0287@2 NA|NA|NA E PFAM Prephenate dehydrogenase HFDCGJPN_00016 640081.Dsui_1942 5.7e-235 820.5 Rhodocyclales cmk GO:0003674,GO:0003824,GO:0003866,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009423,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016765,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390,iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1MWMK@1224,2KUWK@206389,2VGZF@28216,COG0128@1,COG0128@2,COG0283@1,COG0283@2 NA|NA|NA F Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate HFDCGJPN_00017 265072.Mfla_0927 3.6e-294 1016.9 Nitrosomonadales rpsA GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1MVAV@1224,2KP6N@206350,2VI12@28216,COG0539@1,COG0539@2 NA|NA|NA J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence HFDCGJPN_00018 582744.Msip34_1103 6.9e-41 172.9 Nitrosomonadales himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 ko:K05788 ko00000,ko03032,ko03036,ko03400 Bacteria 1MZ7M@1224,2KN0D@206350,2VSPN@28216,COG0776@1,COG0776@2 NA|NA|NA K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control HFDCGJPN_00019 582744.Msip34_1102 2.1e-20 104.8 Nitrosomonadales lapA ko:K08992 ko00000 Bacteria 1PJS6@1224,2KNZW@206350,2W85D@28216,COG5416@1,COG5416@2 NA|NA|NA S Lipopolysaccharide assembly protein A domain HFDCGJPN_00020 582744.Msip34_1101 2e-171 608.6 Nitrosomonadales lapB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 ko:K19804 ko00000 Bacteria 1MVDP@1224,2KKVZ@206350,2VH49@28216,COG2956@1,COG2956@2 NA|NA|NA G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane HFDCGJPN_00021 582744.Msip34_1100 4.8e-91 340.9 Nitrosomonadales pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1MW2C@1224,2KM96@206350,2VJRD@28216,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) HFDCGJPN_00022 582744.Msip34_1099 3e-21 107.8 Nitrosomonadales ybaV GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.1.26.11 ko:K00784,ko:K02237 ko03013,map03013 M00429 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.11.1,3.A.11.2 Bacteria 1N6Q3@1224,2KN8G@206350,2VVT0@28216,COG1555@1,COG1555@2 NA|NA|NA L TIGRFAM competence protein ComEA helix-hairpin-helix repeat HFDCGJPN_00023 1101195.Meth11DRAFT_0950 1.6e-107 396.0 Nitrosomonadales metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Bacteria 1MUBY@1224,2KKUH@206350,2VH19@28216,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation HFDCGJPN_00025 1502770.JQMG01000001_gene875 5.8e-60 237.3 Nitrosomonadales pncA Bacteria 1MU5N@1224,2KMRA@206350,2VUBT@28216,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family HFDCGJPN_00026 1236959.BAMT01000008_gene2471 5e-150 537.7 Nitrosomonadales tolC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 1MWCJ@1224,2KKGH@206350,2VHG1@28216,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM type I secretion outer membrane protein, TolC family HFDCGJPN_00027 1236959.BAMT01000008_gene2466 7e-76 290.4 Nitrosomonadales 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1RD6S@1224,2KMN7@206350,2VJX3@28216,COG2518@1,COG2518@2 NA|NA|NA O PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase HFDCGJPN_00028 395493.BegalDRAFT_1215 1.1e-52 213.0 Gammaproteobacteria mchD Bacteria 1RIIR@1224,1T129@1236,COG5528@1,COG5528@2 NA|NA|NA S integral membrane protein HFDCGJPN_00029 640081.Dsui_0408 0.0 1140.6 Rhodocyclales czcA ko:K18303 M00642 ko00000,ko00002,ko01504,ko02000 2.A.6.2.17 Bacteria 1MU48@1224,2KUT5@206389,2VHZQ@28216,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family HFDCGJPN_00030 582744.Msip34_0565 2.8e-135 488.4 Nitrosomonadales bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,2.8.1.6 ko:K00652,ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078,R03210,R10124 RC00004,RC00039,RC00441,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Bacteria 1MVVH@1224,2KKER@206350,2VH25@28216,COG0156@1,COG0156@2 NA|NA|NA H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide HFDCGJPN_00031 582744.Msip34_0564 8.1e-169 599.7 Nitrosomonadales bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1589,iZ_1308.Z0994 Bacteria 1MVFF@1224,2KMD6@206350,2VHZZ@28216,COG0502@1,COG0502@2 NA|NA|NA H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism HFDCGJPN_00032 582744.Msip34_0563 3.3e-49 201.1 Nitrosomonadales Bacteria 1NB0X@1224,2DPBX@1,2KNWK@206350,2VX47@28216,331FU@2 NA|NA|NA HFDCGJPN_00033 582744.Msip34_0562 2.3e-69 268.9 Nitrosomonadales comF GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 Bacteria 1RHAV@1224,2KMQA@206350,2VSPK@28216,COG1040@1,COG1040@2 NA|NA|NA S Phosphoribosyl transferase domain HFDCGJPN_00034 1132855.KB913035_gene2270 1.6e-71 275.4 Nitrosomonadales trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1RCY4@1224,2KMPS@206350,2VR5W@28216,COG0219@1,COG0219@2 NA|NA|NA J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide HFDCGJPN_00035 265072.Mfla_2183 5e-147 527.3 Nitrosomonadales gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 iSFV_1184.SFV_3923 Bacteria 1MUU3@1224,2KME0@206350,2VJ91@28216,COG0240@1,COG0240@2 NA|NA|NA C PFAM NAD-dependent glycerol-3-phosphate dehydrogenase HFDCGJPN_00036 265072.Mfla_2184 2.8e-48 198.0 Nitrosomonadales MA20_24010 3.2.1.96,3.4.17.14,3.5.1.28,6.1.1.12 ko:K01227,ko:K01447,ko:K01448,ko:K01876,ko:K06385,ko:K07260,ko:K11060,ko:K11062 ko00511,ko00550,ko00970,ko01100,ko01502,ko01503,ko02020,map00511,map00550,map00970,map01100,map01502,map01503,map02020 M00359,M00360,M00651,M00727 R04112,R05577 RC00055,RC00064,RC00141,RC00523 ko00000,ko00001,ko00002,ko01000,ko01002,ko01007,ko01011,ko01504,ko02042,ko03016,ko03029,ko03036 Bacteria 1MZIA@1224,2KN0W@206350,2VUTD@28216,COG3807@1,COG3807@2 NA|NA|NA S Bacterial SH3 domain HFDCGJPN_00037 1236959.BAMT01000002_gene2222 7.6e-61 240.0 Nitrosomonadales secB GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 Bacteria 1RI75@1224,2KMSR@206350,2VQ1Q@28216,COG1952@1,COG1952@2 NA|NA|NA U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA HFDCGJPN_00038 1132855.KB913035_gene2274 7.5e-34 149.4 Nitrosomonadales grxC ko:K03676 ko00000,ko03110 Bacteria 1N72P@1224,2KN2J@206350,2VU2J@28216,COG0695@1,COG0695@2 NA|NA|NA O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins HFDCGJPN_00039 582744.Msip34_0552 5.3e-34 150.6 Nitrosomonadales yibN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 ko:K01011,ko:K02439 ko00270,ko00920,ko01100,ko01110,ko01120,ko04122,map00270,map00920,map01100,map01110,map01120,map04122 R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 Bacteria 1MZ83@1224,2KN1N@206350,2VU3D@28216,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain HFDCGJPN_00040 666681.M301_0570 1.2e-232 812.4 Nitrosomonadales gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 1MUQ1@1224,2KM0U@206350,2VMTN@28216,COG0696@1,COG0696@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate HFDCGJPN_00041 265072.Mfla_2189 5.2e-109 401.4 Nitrosomonadales envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 ko:K06194,ko:K21471 ko00000,ko01000,ko01002,ko01011 1.A.34.1.2 Bacteria 1MY3E@1224,2KKQY@206350,2VIV9@28216,COG4942@1,COG4942@2 NA|NA|NA D Peptidase family M23 HFDCGJPN_00042 582744.Msip34_0727 9.2e-259 899.8 Betaproteobacteria ko:K02652 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1MU7V@1224,2VHQ1@28216,COG2804@1,COG2804@2 NA|NA|NA NU type II secretion system protein E HFDCGJPN_00043 395494.Galf_0016 2.3e-117 429.5 Betaproteobacteria glnL ko:K07719 ko02020,map02020 M00518 ko00000,ko00001,ko00002,ko02022 Bacteria 1NNCT@1224,2VK0Z@28216,COG0457@1,COG0457@2,COG0784@1,COG0784@2 NA|NA|NA T Response regulator receiver HFDCGJPN_00044 582744.Msip34_0548 2.7e-163 581.6 Betaproteobacteria eutG 1.1.1.1,4.3.3.7 ko:K00001,ko:K01714 ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230 M00016,M00525,M00526,M00527 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVPH@1224,2VI90@28216,COG1454@1,COG1454@2 NA|NA|NA C alcohol dehydrogenase HFDCGJPN_00045 582744.Msip34_0547 5e-56 223.8 Nitrosomonadales yjbQ Bacteria 1RH13@1224,2KMR1@206350,2VT5I@28216,COG0432@1,COG0432@2 NA|NA|NA S Uncharacterised protein family UPF0047 HFDCGJPN_00046 1236959.BAMT01000002_gene2214 7.2e-188 663.7 Nitrosomonadales tqsA ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1MW0B@1224,2KMHK@206350,2VHDW@28216,COG0628@1,COG0628@2,COG0664@1,COG0664@2 NA|NA|NA K AI-2E family transporter HFDCGJPN_00047 582744.Msip34_0546 2.2e-45 188.7 Nitrosomonadales Bacteria 1P2XH@1224,2CIM7@1,2KN74@206350,2W46T@28216,345N4@2 NA|NA|NA HFDCGJPN_00048 582744.Msip34_0545 5.3e-95 354.4 Nitrosomonadales slt_1 ko:K07126 ko00000 Bacteria 1MZ4X@1224,2KKV8@206350,2VM6E@28216,COG0741@1,COG0741@2,COG0790@1,COG0790@2 NA|NA|NA M SMART Sel1 domain protein repeat-containing protein HFDCGJPN_00049 582744.Msip34_0542 0.0 1201.4 Nitrosomonadales clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1MURH@1224,2KM7M@206350,2VHYF@28216,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE HFDCGJPN_00050 582744.Msip34_1506 1.3e-131 476.1 Nitrosomonadales fhcB GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 ko:K00201 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03015,R08060 RC00197,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1R64R@1224,2KM62@206350,2VIB0@28216,COG1029@1,COG1029@2 NA|NA|NA C formylmethanofuran dehydrogenase HFDCGJPN_00051 582744.Msip34_1507 9.6e-300 1035.4 Nitrosomonadales fhcA 1.2.7.12 ko:K00200 ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200 M00567 R03015,R08060 RC00197,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1NX13@1224,2KKSB@206350,2VK99@28216,COG1229@1,COG1229@2 NA|NA|NA C Formylmethanofuran dehydrogenase, subunit A HFDCGJPN_00053 1236959.BAMT01000003_gene491 1.4e-11 79.3 Nitrosomonadales Bacteria 1MU7T@1224,2KP8N@206350,2WF3H@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00054 582744.Msip34_0984 9.1e-21 106.3 Nitrosomonadales Bacteria 1PJJB@1224,2BUM0@1,2KN9X@206350,2W814@28216,32PXK@2 NA|NA|NA HFDCGJPN_00055 1101195.Meth11DRAFT_1866 4.1e-58 231.5 Nitrosomonadales nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 ko:K06194,ko:K12943 ko00000 1.A.34.1.2 Bacteria 1RD24@1224,2KKPX@206350,2VINR@28216,COG1388@1,COG1388@2,COG4942@1,COG4942@2 NA|NA|NA DM Lysin motif HFDCGJPN_00056 582744.Msip34_1807 7e-78 296.6 Nitrosomonadales slyD 5.2.1.8 ko:K03775 ko00000,ko01000,ko03110 Bacteria 1RD35@1224,2KMMG@206350,2VQA2@28216,COG1047@1,COG1047@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase HFDCGJPN_00057 1000565.METUNv1_01303 2e-251 875.5 Rhodocyclales Bacteria 1MU2C@1224,2KV5K@206389,2VH3V@28216,COG5001@1,COG5001@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_00058 582744.Msip34_1817 3.7e-90 337.8 Nitrosomonadales mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1MUGX@1224,2KKXU@206350,2VI3Z@28216,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity HFDCGJPN_00060 1165096.ARWF01000001_gene1696 1e-29 136.0 Nitrosomonadales trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1MZ6D@1224,2KN2P@206350,2VU4B@28216,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin HFDCGJPN_00061 1132855.KB913035_gene1354 1.4e-113 416.0 Betaproteobacteria ko:K15270 ko00000,ko02000 2.A.7.3.7 Bacteria 1MXVF@1224,2VKMQ@28216,COG0697@1,COG0697@2 NA|NA|NA EG of the drug metabolite transporter (DMT) superfamily HFDCGJPN_00063 398578.Daci_0892 9.8e-09 66.6 Comamonadaceae Bacteria 1NIRQ@1224,2VY7C@28216,4AI5Y@80864,COG3755@1,COG3755@2 NA|NA|NA S Pfam:DUF1311 HFDCGJPN_00065 1101195.Meth11DRAFT_2458 4.2e-78 298.1 Nitrosomonadales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QTTF@1224,2KKYJ@206350,2VMKQ@28216,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug HFDCGJPN_00066 1101195.Meth11DRAFT_2457 4.3e-33 147.9 Nitrosomonadales Bacteria 1N6WD@1224,2E3CB@1,2KNCV@206350,2WATE@28216,32YBM@2 NA|NA|NA S Domain of unknown function (DUF4154) HFDCGJPN_00070 1173028.ANKO01000058_gene3042 1.2e-18 101.3 Oscillatoriales 3.2.1.4 ko:K01179,ko:K21449 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko02000 1.B.40.2 GH5,GH9 Bacteria 1G1I0@1117,1HAPI@1150,COG1404@1,COG1404@2,COG2931@1,COG2931@2,COG4447@1,COG4447@2 NA|NA|NA Q PFAM Hemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00071 1123368.AUIS01000016_gene2552 8.6e-109 400.6 Acidithiobacillales pilC ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MV4U@1224,1RNV0@1236,2NCMQ@225057,COG1459@1,COG1459@2 NA|NA|NA NU PFAM type II secretion system HFDCGJPN_00072 1123368.AUIS01000016_gene2551 4.5e-196 691.0 Acidithiobacillales pulE-1 ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MU7V@1224,1RMBS@1236,2NCBG@225057,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretion system (T2SS), protein E, N-terminal domain HFDCGJPN_00073 1031711.RSPO_c00799 3.7e-51 209.1 Betaproteobacteria Bacteria 1REWD@1224,2VR80@28216,COG1819@1,COG1819@2 NA|NA|NA CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase HFDCGJPN_00074 365044.Pnap_4013 1.5e-87 330.5 Comamonadaceae Bacteria 1PRBP@1224,2VHDS@28216,4A9SS@80864,COG2831@1,COG2831@2 NA|NA|NA U Haemolysin secretion/activation protein ShlB/FhaC/HecB HFDCGJPN_00075 375286.mma_0010 5e-64 253.8 Oxalobacteraceae Bacteria 1MXIP@1224,2VJ6Y@28216,476AX@75682,COG3210@1,COG3210@2 NA|NA|NA U TIGRFAM filamentous hemagglutinin family N-terminal domain HFDCGJPN_00076 1175306.GWL_44540 6.5e-40 171.0 Oxalobacteraceae Bacteria 1R2K9@1224,2WICR@28216,4796C@75682,COG4254@1,COG4254@2 NA|NA|NA S FecR protein HFDCGJPN_00077 1236959.BAMT01000001_gene1325 2.9e-70 271.6 Nitrosomonadales lolA 6.3.5.1 ko:K01950,ko:K03634 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 1PXDV@1224,2KMKK@206350,2VNNH@28216,COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) HFDCGJPN_00078 582744.Msip34_1191 0.0 1159.8 Nitrosomonadales ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1MVPI@1224,2KKKE@206350,2VHJV@28216,COG1674@1,COG1674@2 NA|NA|NA D Ftsk_gamma HFDCGJPN_00079 1163617.SCD_n02166 4.7e-103 381.3 Betaproteobacteria oxyR ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1MVA1@1224,2VIBJ@28216,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator HFDCGJPN_00080 666681.M301_1572 2.1e-71 275.0 Nitrosomonadales dps ko:K04047 ko00000,ko03036 Bacteria 1RAC5@1224,2KMKR@206350,2VHJI@28216,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family HFDCGJPN_00081 1132855.KB913035_gene1147 3.8e-160 570.9 Nitrosomonadales trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K03671,ko:K22345 ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 1MV15@1224,2KMFY@206350,2VIVV@28216,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family HFDCGJPN_00082 265072.Mfla_1118 1.6e-75 288.9 Nitrosomonadales yfcN Bacteria 1RH34@1224,2KMB7@206350,2VQ2S@28216,COG2840@1,COG2840@2 NA|NA|NA S Small MutS-related domain HFDCGJPN_00083 582744.Msip34_1186 7e-133 480.7 Nitrosomonadales ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1R744@1224,2KKZE@206350,2VJW4@28216,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein HFDCGJPN_00084 1387312.BAUS01000004_gene1624 1.2e-128 466.5 Nitrosomonadales ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 1MVAS@1224,2KKYQ@206350,2VI8Z@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_00085 582744.Msip34_1184 0.0 1625.1 Nitrosomonadales ko:K15726 ko00000,ko02000 2.A.6.1.2 Bacteria 1NUIV@1224,2KM5P@206350,2VKKR@28216,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family HFDCGJPN_00086 1236959.BAMT01000002_gene2149 1.1e-200 706.1 Nitrosomonadales fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUR8@1224,2KKID@206350,2VKR6@28216,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family HFDCGJPN_00087 358220.C380_05155 1.1e-46 193.4 Comamonadaceae 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1V@1224,2VJ72@28216,4ABWU@80864,COG2114@1,COG2114@2 NA|NA|NA T Adenylate cyclase HFDCGJPN_00088 1163617.SCD_n01957 3.9e-284 983.8 Betaproteobacteria acsA 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MUF5@1224,2VIP3@28216,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA HFDCGJPN_00089 1165096.ARWF01000001_gene2364 7.7e-115 420.2 Nitrosomonadales citE 3.1.2.30,4.1.3.25,4.1.3.34 ko:K01644,ko:K14451,ko:K18292 ko00630,ko00660,ko01100,ko01120,ko01200,ko02020,map00630,map00660,map01100,map01120,map01200,map02020 M00373 R00237,R00362,R10612 RC00004,RC00014,RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0A@1224,2KMIY@206350,2VQR0@28216,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family HFDCGJPN_00090 395494.Galf_0005 5.7e-144 517.3 Betaproteobacteria mch GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 ko:K07068,ko:K14449 ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200 M00373,M00376,M00740 R05076 RC01984 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW4N@1224,2VJZM@28216,COG2030@1,COG2030@2 NA|NA|NA I PFAM MaoC domain protein dehydratase HFDCGJPN_00091 1122236.KB905141_gene636 4.7e-153 547.4 Nitrosomonadales citE 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1Q91U@1224,2KM2P@206350,2VJJY@28216,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family HFDCGJPN_00092 1132855.KB913035_gene2056 8.3e-133 479.9 Nitrosomonadales prpB 4.1.3.30 ko:K03417 ko00640,map00640 R00409 RC00286,RC00287 ko00000,ko00001,ko01000 Bacteria 1N4VT@1224,2KM4V@206350,2VI8S@28216,COG2513@1,COG2513@2 NA|NA|NA G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate HFDCGJPN_00093 1165096.ARWF01000001_gene2360 3.1e-180 637.9 Nitrosomonadales prpC GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630 Bacteria 1MUKX@1224,2KM6P@206350,2VHJZ@28216,COG0372@1,COG0372@2 NA|NA|NA C TIGRFAM 2-methylcitrate synthase citrate synthase II HFDCGJPN_00095 666681.M301_1598 1.3e-189 669.1 Nitrosomonadales amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1NR9F@1224,2KNM5@206350,2VJ8B@28216,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family HFDCGJPN_00096 582744.Msip34_0500 1.4e-08 65.9 Betaproteobacteria Bacteria 1NG92@1224,2EMB8@1,2VXTV@28216,33F08@2 NA|NA|NA HFDCGJPN_00097 1132855.KB913035_gene180 2e-219 768.8 Nitrosomonadales Bacteria 1MVCM@1224,2KNPX@206350,2VMSK@28216,COG1368@1,COG1368@2 NA|NA|NA M Sulfatase HFDCGJPN_00098 1443111.JASG01000004_gene971 5.5e-158 564.3 Sulfitobacter nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1MU1Q@1224,2TT58@28211,3ZWG0@60136,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration HFDCGJPN_00099 582744.Msip34_0217 1.5e-251 875.2 Nitrosomonadales ahpF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 ko:K03387 ko00000,ko01000 Bacteria 1MUKD@1224,2KM80@206350,2VJ01@28216,COG3634@1,COG3634@2 NA|NA|NA C Alkyl hydroperoxide reductase, F subunit HFDCGJPN_00100 582744.Msip34_0216 4.7e-97 360.5 Nitrosomonadales ahpC GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1MWPY@1224,2KMM9@206350,2VI7T@28216,COG0450@1,COG0450@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_00101 1110502.TMO_0560 1.5e-08 66.6 Rhodospirillales Bacteria 1N3ZZ@1224,2JTBD@204441,2UF06@28211,COG3172@1,COG3172@2 NA|NA|NA H AAA domain HFDCGJPN_00103 1502770.JQMG01000001_gene2166 4.5e-71 273.9 Nitrosomonadales smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1RDFP@1224,2KMNZ@206350,2VRG9@28216,COG0691@1,COG0691@2 NA|NA|NA O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene HFDCGJPN_00104 582744.Msip34_1230 2e-55 221.9 Nitrosomonadales ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 ko:K18588 ko00000 Bacteria 1RGUH@1224,2KMT8@206350,2VR4X@28216,COG2867@1,COG2867@2 NA|NA|NA I Polyketide cyclase / dehydrase and lipid transport HFDCGJPN_00105 583345.Mmol_0961 4.9e-35 153.7 Nitrosomonadales rnfH ko:K03154,ko:K09801 ko04122,map04122 ko00000,ko00001 Bacteria 1MZCH@1224,2KN9N@206350,2VVNX@28216,COG2914@1,COG2914@2 NA|NA|NA S Belongs to the UPF0125 (RnfH) family HFDCGJPN_00106 582744.Msip34_1228 6.2e-11 74.3 Nitrosomonadales Bacteria 1RHH4@1224,2BCK1@1,2KN8W@206350,2VSPG@28216,32662@2 NA|NA|NA S Domain of unknown function (DUF4124) HFDCGJPN_00107 582744.Msip34_1227 3.8e-244 850.5 Nitrosomonadales guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1MUJM@1224,2KKNK@206350,2VH9X@28216,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth HFDCGJPN_00108 1123367.C666_10530 5.3e-11 73.6 Betaproteobacteria Bacteria 1NPWH@1224,2BVI1@1,2W4HU@28216,32QWD@2 NA|NA|NA HFDCGJPN_00109 1123367.C666_10530 7.8e-45 187.2 Betaproteobacteria Bacteria 1NPWH@1224,2BVI1@1,2W4HU@28216,32QWD@2 NA|NA|NA HFDCGJPN_00111 1101195.Meth11DRAFT_2595 3.5e-17 94.0 Nitrosomonadales yqiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K09806 ko00000 Bacteria 1N7AH@1224,2KN9G@206350,2VVR4@28216,COG2960@1,COG2960@2 NA|NA|NA S Membrane fusogenic activity HFDCGJPN_00112 1132855.KB913035_gene283 8.8e-220 769.6 Nitrosomonadales comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K07391 ko00000 Bacteria 1MU4R@1224,2KM06@206350,2VHRV@28216,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI HFDCGJPN_00113 582744.Msip34_2585 2.7e-111 408.7 Nitrosomonadales Bacteria 1MUZE@1224,2KMMS@206350,2VJ27@28216,COG1814@1,COG1814@2 NA|NA|NA S VIT family HFDCGJPN_00114 582744.Msip34_2584 0.0 2268.4 Nitrosomonadales metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 Bacteria 1MV6G@1224,2KKBF@206350,2VHYQ@28216,COG0646@1,COG0646@2,COG1410@1,COG1410@2 NA|NA|NA E Vitamin B12 dependent methionine synthase activation HFDCGJPN_00115 582744.Msip34_2583 2.4e-165 588.6 Nitrosomonadales Bacteria 1MVW1@1224,2KKE7@206350,2VKZY@28216,COG3434@1,COG3434@2 NA|NA|NA T PFAM EAL domain HFDCGJPN_00116 582744.Msip34_2582 4.5e-213 747.3 Nitrosomonadales murC 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1MUC5@1224,2KMB0@206350,2VIX5@28216,COG0773@1,COG0773@2 NA|NA|NA M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate HFDCGJPN_00117 1132855.KB913035_gene1901 2e-107 395.6 Nitrosomonadales Bacteria 1RBFV@1224,2KMAR@206350,2VQEZ@28216,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family HFDCGJPN_00118 582744.Msip34_1294 2.3e-169 601.7 Nitrosomonadales uptC ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1QTTX@1224,2KM6D@206350,2VHU7@28216,COG5008@1,COG5008@2 NA|NA|NA NU PFAM type II secretion system protein E HFDCGJPN_00119 1112274.KI911560_gene2278 0.0 1142.5 Nitrosomonadales Bacteria 1R93T@1224,2KMDY@206350,2VPB4@28216,COG2199@1,COG2199@2,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_00120 1132855.KB913035_gene1363 4e-254 884.0 Betaproteobacteria Bacteria 1MU2C@1224,2VH3V@28216,COG5001@1,COG5001@2 NA|NA|NA T Diguanylate cyclase HFDCGJPN_00121 583345.Mmol_1226 6.8e-42 176.8 Nitrosomonadales divK ko:K11443 ko02020,ko04112,map02020,map04112 M00511 ko00000,ko00001,ko00002,ko02022 Bacteria 1QU3I@1224,2KNXS@206350,2WGTG@28216,COG0784@1,COG0784@2 NA|NA|NA T cheY-homologous receiver domain HFDCGJPN_00122 1132855.KB913035_gene1365 5.5e-216 757.7 Proteobacteria 2.7.13.3 ko:K02484,ko:K14986 ko02020,map02020 M00524 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1NRP8@1224,COG0642@1,COG2203@1,COG2203@2,COG2205@2 NA|NA|NA T PhoQ Sensor HFDCGJPN_00123 582744.Msip34_1296 7.5e-169 600.9 Nitrosomonadales Bacteria 1MVMG@1224,2KKW3@206350,2VH3M@28216,COG0457@1,COG0457@2,COG3914@1,COG3914@2 NA|NA|NA O Glycosyl transferase family 41 HFDCGJPN_00124 1101195.Meth11DRAFT_1312 2.6e-184 652.1 Nitrosomonadales mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 ko:K00773,ko:K07319,ko:K11782,ko:K15461 ko00130,ko01110,map00130,map01110 R00601,R03789,R08702,R10209,R10666 RC00003,RC00053,RC00060,RC00063,RC01483,RC03232 ko00000,ko00001,ko01000,ko02048,ko03016 Bacteria 1MZW5@1224,2KMCW@206350,2VHGY@28216,COG0665@1,COG0665@2,COG4121@1,COG4121@2 NA|NA|NA E Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 HFDCGJPN_00125 402626.Rpic_4126 1.9e-80 306.2 Burkholderiaceae Bacteria 1K2D4@119060,1R7HC@1224,2VQ62@28216,COG2199@1,COG3706@2 NA|NA|NA T Diguanylate cyclase HFDCGJPN_00126 265072.Mfla_1394 6.6e-45 187.2 Nitrosomonadales 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 1RE7I@1224,2KPA4@206350,2VR4M@28216,COG2227@1,COG2227@2 NA|NA|NA H Tellurite resistance protein TehB HFDCGJPN_00127 582744.Msip34_1299 7.6e-180 636.7 Nitrosomonadales cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 iJN746.PP_2734 Bacteria 1MX3U@1224,2KP5H@206350,2VJ00@28216,COG2230@1,COG2230@2 NA|NA|NA M Mycolic acid cyclopropane synthetase HFDCGJPN_00128 582744.Msip34_1300 7.5e-93 347.1 Nitrosomonadales 2.1.1.79 ko:K00574,ko:K09701 ko00000,ko01000 Bacteria 1RC56@1224,2KKWX@206350,2VIZ9@28216,COG3496@1,COG3496@2 NA|NA|NA S Protein of unknown function (DUF1365) HFDCGJPN_00129 582744.Msip34_1301 3e-197 694.5 Nitrosomonadales ko:K06954 ko00000 Bacteria 1MV4Z@1224,2KKWV@206350,2VHCR@28216,COG2907@1,COG2907@2 NA|NA|NA S Flavin containing amine oxidoreductase HFDCGJPN_00130 1165096.ARWF01000001_gene237 2.9e-131 474.9 Nitrosomonadales desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 1N2MA@1224,2KKMK@206350,2VMFC@28216,COG1398@1,COG1398@2 NA|NA|NA I Fatty acid desaturase HFDCGJPN_00131 1502770.JQMG01000001_gene1712 5.2e-56 224.2 Nitrosomonadales blc4 ko:K03098 ko00000,ko04147 Bacteria 1RIKA@1224,2KMTG@206350,2VTSY@28216,COG3040@1,COG3040@2 NA|NA|NA M Lipocalin-like domain HFDCGJPN_00132 582744.Msip34_1304 1.9e-56 225.7 Nitrosomonadales Bacteria 1N3G5@1224,2KMRW@206350,2VUMZ@28216,COG4338@1,COG4338@2 NA|NA|NA S Protein conserved in bacteria HFDCGJPN_00133 666681.M301_1471 2.3e-94 352.1 Nitrosomonadales yfhH 1.3.1.22 ko:K12343 ko00140,map00140 R02208,R02497,R08954,R10242 RC00145 ko00000,ko00001,ko01000 Bacteria 1MXCP@1224,2KKZM@206350,2VQHY@28216,COG3752@1,COG3752@2 NA|NA|NA S Phospholipid methyltransferase HFDCGJPN_00134 666681.M301_1470 2.4e-34 152.1 Nitrosomonadales Bacteria 1N8YD@1224,2CH72@1,2KN4M@206350,2VVUJ@28216,32ZK4@2 NA|NA|NA S Protein of unknown function (DUF2878) HFDCGJPN_00135 666681.M301_1469 7.5e-149 533.5 Nitrosomonadales cfa 2.1.1.79 ko:K00574 ko00000,ko01000 Bacteria 1MUW5@1224,2KMFN@206350,2VI5F@28216,COG2230@1,COG2230@2 NA|NA|NA M Putative methyltransferase HFDCGJPN_00136 582744.Msip34_1308 4.8e-112 411.0 Betaproteobacteria ycgE ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1R2NF@1224,2VJDG@28216,COG0789@1,COG0789@2,COG5012@1,COG5012@2 NA|NA|NA K PFAM regulatory protein, MerR HFDCGJPN_00137 1165096.ARWF01000001_gene245 1.7e-238 832.0 Nitrosomonadales Bacteria 1MUQX@1224,2KMF9@206350,2VMVP@28216,COG4993@1,COG4993@2 NA|NA|NA G PQQ-like domain HFDCGJPN_00138 1485544.JQKP01000010_gene793 2.7e-154 553.1 Nitrosomonadales Bacteria 1MU2C@1224,2W8ZJ@28216,44WED@713636,COG5001@1,COG5001@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_00139 670292.JH26_17705 6e-29 134.0 Methylobacteriaceae srpB ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1JWU5@119045,1MURJ@1224,2U5UM@28211,COG1285@1,COG1285@2 NA|NA|NA S MgtC family HFDCGJPN_00140 1165096.ARWF01000001_gene401 1.4e-232 812.4 Nitrosomonadales kefB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006885,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010033,GO:0015075,GO:0015077,GO:0015079,GO:0015291,GO:0015318,GO:0015503,GO:0015643,GO:0015672,GO:0016020,GO:0016021,GO:0019899,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051595,GO:0055067,GO:0055080,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1901654,GO:1901700 ko:K03455,ko:K11745,ko:K11747 ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 iB21_1397.B21_03153,iEC55989_1330.EC55989_3754,iECBD_1354.ECBD_0398,iECB_1328.ECB_03201,iECD_1391.ECD_03201,iECO26_1355.ECO26_4439,iECOK1_1307.ECOK1_0046,iECS88_1305.ECS88_0050,iECSE_1348.ECSE_3612,iECW_1372.ECW_m3606,iEKO11_1354.EKO11_0394,iEcHS_1320.EcHS_A3547,iSFV_1184.SFV_3356,iSSON_1240.SSON_3481,iUMN146_1321.UM146_23015,iUTI89_1310.UTI89_C0053,iWFL_1372.ECW_m3606,iYL1228.KPN_03736 Bacteria 1MV34@1224,2KM44@206350,2VHQQ@28216,COG0475@1,COG0475@2,COG1226@1,COG1226@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family HFDCGJPN_00143 582744.Msip34_0644 9.3e-17 92.4 Nitrosomonadales Bacteria 1P4G2@1224,2CA46@1,2KP1D@206350,2W6FA@28216,2ZEVF@2 NA|NA|NA HFDCGJPN_00144 265072.Mfla_2086 8.3e-89 333.6 Nitrosomonadales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 1N3GB@1224,2KMUJ@206350,2VSGK@28216,COG1192@1,COG1192@2 NA|NA|NA D AAA domain HFDCGJPN_00145 1132855.KB913035_gene1029 1.7e-155 555.8 Nitrosomonadales 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1MUUH@1224,2KMEY@206350,2VNAY@28216,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family HFDCGJPN_00146 1132855.KB913035_gene1028 1.1e-76 292.7 Nitrosomonadales msrA 1.8.4.11 ko:K07304 ko00000,ko01000 Bacteria 1MVUS@1224,2KMMF@206350,2VR6F@28216,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine HFDCGJPN_00147 582744.Msip34_0649 4.7e-60 239.6 Nitrosomonadales fimV ko:K08086 ko00000 Bacteria 1MXV7@1224,2KMD2@206350,2VHX1@28216,COG3170@1,COG3170@2 NA|NA|NA NU pilus assembly protein FimV HFDCGJPN_00148 583345.Mmol_0666 1.1e-129 469.9 Nitrosomonadales corA GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1MX09@1224,2KKEF@206350,2VHCH@28216,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions HFDCGJPN_00149 582744.Msip34_0648 9.3e-143 513.1 Nitrosomonadales cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUBE@1224,2KMBQ@206350,2VJI3@28216,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family HFDCGJPN_00150 583345.Mmol_0788 1.7e-152 545.8 Nitrosomonadales yhcA ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1PBKH@1224,2KP42@206350,2VKXU@28216,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain HFDCGJPN_00151 1132855.KB913035_gene1961 4.1e-153 547.7 Nitrosomonadales yhcA ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1PBKH@1224,2KP41@206350,2VIIH@28216,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain HFDCGJPN_00152 159087.Daro_3462 3.1e-90 338.2 Rhodocyclales macB ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1MU45@1224,2KVSB@206389,2VJBY@28216,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities HFDCGJPN_00153 1132855.KB913035_gene1963 6.1e-144 517.3 Betaproteobacteria macA ko:K02005,ko:K13888 M00709 ko00000,ko00002,ko02000 8.A.1 Bacteria 1MU8D@1224,2VJR5@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_00154 1502770.JQMG01000001_gene177 3.3e-82 311.2 Nitrosomonadales Bacteria 1NB1B@1224,2KM4U@206350,2VQ0V@28216,COG1853@1,COG1853@2 NA|NA|NA S PFAM flavin reductase domain protein FMN-binding HFDCGJPN_00156 395965.Msil_2175 7.3e-47 194.5 Proteobacteria ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1N7UQ@1224,COG1475@1,COG1475@2 NA|NA|NA K ParB-like nuclease domain HFDCGJPN_00157 375286.mma_0578 1.5e-56 226.5 Oxalobacteraceae dam GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047 2.1.1.37,2.1.1.72 ko:K00558,ko:K06223 ko00270,ko01100,ko03430,ko05206,map00270,map01100,map03430,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1P85S@1224,2VKN7@28216,4755G@75682,COG0338@1,COG0338@2 NA|NA|NA H D12 class N6 adenine-specific DNA methyltransferase HFDCGJPN_00158 582744.Msip34_0651 1.2e-272 945.3 Nitrosomonadales glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECIAI39_1322.ECIAI39_0637 Bacteria 1MUC8@1224,2KKQ1@206350,2VHZX@28216,COG0008@1,COG0008@2 NA|NA|NA J TIGRFAM glutaminyl-tRNA synthetase HFDCGJPN_00159 265072.Mfla_1116 4.6e-75 287.7 Nitrosomonadales ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21030,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS20335 Bacteria 1MY3B@1224,2KMKI@206350,2VMD6@28216,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) HFDCGJPN_00160 1236959.BAMT01000004_gene972 1.6e-16 91.7 Nitrosomonadales fdsD 1.17.1.9 ko:K00126 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 R00519 RC02796 ko00000,ko00001,ko01000 Bacteria 1N7UZ@1224,2E4CR@1,2KN8K@206350,2VVR1@28216,32Z86@2 NA|NA|NA S NADH-dependant formate dehydrogenase delta subunit FdsD HFDCGJPN_00161 582744.Msip34_1180 5.8e-88 330.9 Nitrosomonadales fdhD GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363 ko:K02379 ko00000 Bacteria 1NRU0@1224,2KM64@206350,2VQ5Z@28216,COG1526@1,COG1526@2 NA|NA|NA C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH HFDCGJPN_00162 582744.Msip34_1179 0.0 1673.3 Nitrosomonadales fdsA 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 Bacteria 1QTZB@1224,2KKYD@206350,2VP2Q@28216,COG3383@1,COG3383@2 NA|NA|NA C TIGRFAM formate dehydrogenase, alpha subunit HFDCGJPN_00163 1101195.Meth11DRAFT_2316 1.7e-253 881.7 Nitrosomonadales fdsB 1.6.5.3 ko:K00124,ko:K00335 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MV8F@1224,2KKNQ@206350,2VIGR@28216,COG1894@1,COG1894@2 NA|NA|NA C PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit HFDCGJPN_00164 265072.Mfla_0722 5.6e-59 233.8 Nitrosomonadales fdsG 1.6.5.3 ko:K00124,ko:K00127,ko:K00334,ko:K00335 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1RHBU@1224,2KMRQ@206350,2VSVZ@28216,COG1905@1,COG1905@2 NA|NA|NA C PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit HFDCGJPN_00165 666681.M301_1209 1.2e-163 583.6 Nitrosomonadales acoR ko:K21405 ko00000,ko03000 Bacteria 1NRG5@1224,2KKV7@206350,2VICI@28216,COG3284@1,COG3284@2 NA|NA|NA KQ GAF domain HFDCGJPN_00166 583345.Mmol_0791 7e-265 919.5 Nitrosomonadales aldA 1.2.1.3 ko:K00128,ko:K00138,ko:K18370 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00640,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00640,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R10703 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00545,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU1V@1224,2KM04@206350,2VHNV@28216,COG1012@1,COG1012@2 NA|NA|NA C PFAM Aldehyde dehydrogenase HFDCGJPN_00167 666681.M301_0903 7e-49 199.9 Nitrosomonadales ko:K09959 ko00000 Bacteria 1RGYH@1224,2KN6J@206350,2VSRW@28216,COG3564@1,COG3564@2 NA|NA|NA S Protein of unknown function (DUF779) HFDCGJPN_00168 582744.Msip34_1153 4.9e-197 693.7 Nitrosomonadales amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1NR9F@1224,2KKIZ@206350,2VI9I@28216,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family HFDCGJPN_00169 582744.Msip34_1147 1.4e-201 709.1 Nitrosomonadales pap Bacteria 1MVE2@1224,2KKKJ@206350,2VGZV@28216,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) HFDCGJPN_00170 582744.Msip34_1146 6.9e-58 230.7 Nitrosomonadales Bacteria 1NM2K@1224,2EM7S@1,2KMSQ@206350,2VYUH@28216,33EWW@2 NA|NA|NA HFDCGJPN_00171 582744.Msip34_1146 3.6e-64 251.5 Nitrosomonadales Bacteria 1NM2K@1224,2EM7S@1,2KMSQ@206350,2VYUH@28216,33EWW@2 NA|NA|NA HFDCGJPN_00172 265072.Mfla_1111 6.3e-189 666.8 Nitrosomonadales pilU ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1QTTX@1224,2KNIN@206350,2VIWS@28216,COG5008@1,COG5008@2 NA|NA|NA NU Type II/IV secretion system protein HFDCGJPN_00173 582744.Msip34_1144 8.6e-107 393.7 Nitrosomonadales gluQ GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 ko:K01894 ko00000,ko01000,ko01007,ko03016 Bacteria 1MUN7@1224,2KM5R@206350,2VHYK@28216,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon HFDCGJPN_00174 582744.Msip34_2246 1.3e-154 552.7 Nitrosomonadales cusB ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 1MVAS@1224,2KKX1@206350,2VN6Q@28216,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like HFDCGJPN_00175 1236959.BAMT01000005_gene185 1.8e-139 502.7 Nitrosomonadales cusC ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1R6S1@1224,2KP5M@206350,2VMHP@28216,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein HFDCGJPN_00177 582744.Msip34_2249 1.9e-216 758.4 Nitrosomonadales cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1MV8H@1224,2KM9D@206350,2VHN4@28216,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family HFDCGJPN_00178 1165096.ARWF01000001_gene2116 1.1e-65 257.3 Nitrosomonadales Bacteria 1Q84V@1224,2KKK5@206350,2VJAQ@28216,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat HFDCGJPN_00179 582744.Msip34_2251 7.8e-150 537.0 Nitrosomonadales pgp2 Bacteria 1N2B6@1224,2KKJC@206350,2VJXB@28216,COG3034@1,COG3034@2 NA|NA|NA S PFAM ErfK YbiS YcfS YnhG family protein HFDCGJPN_00180 583345.Mmol_0508 5.3e-56 224.2 Nitrosomonadales 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1R9ZQ@1224,2KMU4@206350,2VQ3Z@28216,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides HFDCGJPN_00181 582744.Msip34_2253 7.9e-77 293.1 Nitrosomonadales ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.7.11.1,5.2.1.8 ko:K03767,ko:K03768,ko:K08884 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko01001,ko03110,ko04147 Bacteria 1R9ZQ@1224,2KMNN@206350,2VQ3Z@28216,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides HFDCGJPN_00182 265072.Mfla_0495 9.1e-85 320.1 Nitrosomonadales lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 iE2348C_1286.E2348C_0457 Bacteria 1N3U7@1224,2KMGY@206350,2VQRP@28216,COG2908@1,COG2908@2 NA|NA|NA S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell HFDCGJPN_00183 1101195.Meth11DRAFT_2040 4.5e-13 80.5 Nitrosomonadales nuoF 1.12.1.3 ko:K17992 ko00000,ko01000 Bacteria 1P6KD@1224,2KP3K@206350,2W59B@28216,COG3411@1,COG3411@2 NA|NA|NA C Ferredoxin HFDCGJPN_00185 666681.M301_0511 4.2e-231 807.4 Nitrosomonadales 3.1.4.17 ko:K01120 ko00230,map00230 R00191,R01234 RC00296 ko00000,ko00001,ko01000 Bacteria 1MV37@1224,2KNE7@206350,2VJ21@28216,COG2203@1,COG2203@2,COG2206@1,COG2206@2 NA|NA|NA T GAF domain HFDCGJPN_00186 666681.M301_0510 2.2e-70 272.3 Nitrosomonadales Bacteria 1MW1M@1224,2KN77@206350,2VJ1K@28216,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain HFDCGJPN_00187 666681.M301_0509 4.3e-99 367.9 Nitrosomonadales pppL 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 1R7UF@1224,2KNQP@206350,2VM6F@28216,COG0631@1,COG0631@2 NA|NA|NA T PFAM Protein phosphatase HFDCGJPN_00188 580332.Slit_0530 0.0 1134.4 Betaproteobacteria 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1MV1P@1224,2VKJ8@28216,COG0515@1,COG0515@2,COG4252@1,COG4252@2 NA|NA|NA KLT serine threonine protein kinase HFDCGJPN_00189 582744.Msip34_2256 1.9e-48 198.7 Nitrosomonadales nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03625 ko00000,ko03009,ko03021 Bacteria 1RHFZ@1224,2KMZN@206350,2VSI6@28216,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons HFDCGJPN_00190 666681.M301_0507 1.2e-60 239.2 Nitrosomonadales ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825 Bacteria 1RD9J@1224,2KMQU@206350,2VQGE@28216,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin HFDCGJPN_00191 265072.Mfla_0489 3.8e-117 427.6 Nitrosomonadales Bacteria 1MY2Z@1224,2KKPH@206350,2VIT4@28216,COG0745@1,COG0745@2 NA|NA|NA T TIGRFAM phosphate regulon transcriptional regulatory protein PhoB HFDCGJPN_00192 582744.Msip34_2260 2.5e-186 658.3 Nitrosomonadales phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K02484,ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWF3@1224,2KKZ5@206350,2VIBV@28216,COG5002@1,COG5002@2 NA|NA|NA T TIGRFAM phosphate regulon sensor kinase PhoR HFDCGJPN_00194 1132855.KB913035_gene667 9.4e-13 79.0 Nitrosomonadales ydhL ko:K06938 ko00000 Bacteria 1NGD5@1224,2KNDD@206350,2W822@28216,COG3313@1,COG3313@2 NA|NA|NA S Protein of unknown function (DUF1289) HFDCGJPN_00195 265072.Mfla_2234 0.0 1524.6 Nitrosomonadales secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1MUJZ@1224,2KKHN@206350,2VHDH@28216,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane HFDCGJPN_00196 582744.Msip34_0497 9.1e-100 370.2 Nitrosomonadales nlpD_1 3.4.24.75 ko:K08259,ko:K21472 ko00000,ko01000,ko01002,ko01011 Bacteria 1MVTF@1224,2KKDK@206350,2VKR8@28216,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 HFDCGJPN_00197 265072.Mfla_2236 1.2e-28 132.9 Nitrosomonadales Z012_02020 Bacteria 1NHRC@1224,2KP89@206350,2VWI9@28216,COG4701@1,COG4701@2 NA|NA|NA S Protein of unknown function (DUF721) HFDCGJPN_00198 1236959.BAMT01000002_gene2169 9.8e-72 276.9 Nitrosomonadales ko:K07090 ko00000 Bacteria 1R3V4@1224,2KMVZ@206350,2VKXN@28216,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein HFDCGJPN_00199 582744.Msip34_0494 8.6e-99 366.7 Nitrosomonadales MA20_23390 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUX3@1224,2KNEB@206350,2WHA3@28216,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter HFDCGJPN_00200 582744.Msip34_0493 5.4e-115 420.6 Nitrosomonadales MA20_23385 ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUF4@1224,2KNNH@206350,2W3RW@28216,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter HFDCGJPN_00201 1101195.Meth11DRAFT_2254 0.0 1124.4 Nitrosomonadales hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 1MUQ3@1224,2KNHQ@206350,2VI3K@28216,COG3808@1,COG3808@2 NA|NA|NA C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force HFDCGJPN_00202 1101195.Meth11DRAFT_2255 8.8e-85 319.7 Nitrosomonadales ppa 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iJN746.PP_0538 Bacteria 1RA2F@1224,2KKIH@206350,2VQC0@28216,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions HFDCGJPN_00203 582744.Msip34_0490 3.4e-80 304.7 Nitrosomonadales ybcF 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1MZCY@1224,2KN8M@206350,2VV31@28216,COG0288@1,COG0288@2,COG3339@1,COG3339@2 NA|NA|NA P Protein of unknown function (DUF1232) HFDCGJPN_00204 582744.Msip34_0489 1.7e-141 508.8 Nitrosomonadales purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1MUR9@1224,2KMDV@206350,2VGZK@28216,COG0152@1,COG0152@2 NA|NA|NA F PFAM SAICAR synthetase HFDCGJPN_00205 582744.Msip34_0488 5e-56 223.8 Nitrosomonadales VP0175 ko:K13256 ko00000 Bacteria 1N0MS@1224,2KN5Y@206350,2VUQQ@28216,COG3223@1,COG3223@2 NA|NA|NA S Belongs to the PsiE family HFDCGJPN_00206 666681.M301_2164 1.8e-147 528.9 Nitrosomonadales fba 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iJN746.PP_4960 Bacteria 1MURX@1224,2KMGX@206350,2VHGI@28216,COG0191@1,COG0191@2 NA|NA|NA G fructose-bisphosphate aldolase, class II, Calvin cycle subtype HFDCGJPN_00207 582744.Msip34_0486 3.7e-191 674.5 Nitrosomonadales pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 Bacteria 1MU21@1224,2KM48@206350,2VHN5@28216,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family HFDCGJPN_00208 582744.Msip34_0485 4.1e-188 664.1 Nitrosomonadales pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSbBS512_1146.SbBS512_E3351 Bacteria 1MUNU@1224,2KKQP@206350,2VHJK@28216,COG0126@1,COG0126@2 NA|NA|NA G Belongs to the phosphoglycerate kinase family HFDCGJPN_00209 1236959.BAMT01000002_gene2157 7.1e-173 613.2 Nitrosomonadales gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 Bacteria 1MU93@1224,2KMB2@206350,2VHHG@28216,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family HFDCGJPN_00210 582744.Msip34_0483 0.0 1260.7 Nitrosomonadales tkt GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Bacteria 1MUEY@1224,2KKF0@206350,2VHNX@28216,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate HFDCGJPN_00211 582744.Msip34_0482 3.7e-89 335.1 Betaproteobacteria Bacteria 1R6GI@1224,2VM5N@28216,COG2199@1,COG3706@2 NA|NA|NA T Diguanylate cyclase HFDCGJPN_00212 1101195.Meth11DRAFT_2271 1.4e-77 295.8 Nitrosomonadales Bacteria 1R9YF@1224,2KMA9@206350,2VN9B@28216,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_00213 1101195.Meth11DRAFT_2272 8.8e-80 303.5 Nitrosomonadales rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1MXCU@1224,2KMH0@206350,2VJS2@28216,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit HFDCGJPN_00214 1101195.Meth11DRAFT_0506 1.4e-240 839.3 Nitrosomonadales Bacteria 1MU2C@1224,2KMBP@206350,2VH3V@28216,COG0715@1,COG0715@2,COG5001@1,COG5001@2 NA|NA|NA T PFAM EAL domain HFDCGJPN_00215 1132855.KB913035_gene1779 5.3e-27 127.5 Nitrosomonadales flgN ko:K02399 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1NGUP@1224,2KN6F@206350,2VXS1@28216,COG3418@1,COG3418@2 NA|NA|NA NOU FlgN protein HFDCGJPN_00216 666681.M301_1703 1.6e-16 92.0 Nitrosomonadales flgM GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Bacteria 1NGJA@1224,2KN88@206350,2VXZB@28216,COG2747@1,COG2747@2 NA|NA|NA KNU PFAM Anti-sigma-28 factor FlgM HFDCGJPN_00217 1132855.KB913035_gene1781 2.8e-70 271.9 Nitrosomonadales flgA GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 ko:K02279,ko:K02386 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Bacteria 1N1SA@1224,2KMBU@206350,2VR6V@28216,COG1261@1,COG1261@2 NA|NA|NA N flagella basal body P-ring formation protein FlgA HFDCGJPN_00218 583345.Mmol_0950 4.8e-43 180.6 Nitrosomonadales flgB GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZ8P@1224,2KN01@206350,2VUJ4@28216,COG1815@1,COG1815@2 NA|NA|NA N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body HFDCGJPN_00219 1101195.Meth11DRAFT_1532 2.7e-54 218.0 Nitrosomonadales flgC GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009425,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1RHI3@1224,2KMTP@206350,2VSK1@28216,COG1558@1,COG1558@2 NA|NA|NA N Belongs to the flagella basal body rod proteins family HFDCGJPN_00220 1101195.Meth11DRAFT_1533 1.6e-64 252.7 Nitrosomonadales flgD GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044424,GO:0044444,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02389,ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MXCG@1224,2KMM2@206350,2VSF6@28216,COG1843@1,COG1843@2 NA|NA|NA N Required for flagellar hook formation. May act as a scaffolding protein HFDCGJPN_00221 1165096.ARWF01000001_gene907 7.2e-159 567.0 Nitrosomonadales flgE GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044424,GO:0044444,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MU5J@1224,2KKP1@206350,2VIV1@28216,COG1749@1,COG1749@2 NA|NA|NA N Flagellar basal body rod HFDCGJPN_00222 1502770.JQMG01000001_gene2183 1.6e-100 372.5 Nitrosomonadales flgF GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009425,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02391 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1NZWQ@1224,2KM1W@206350,2VISC@28216,COG4787@1,COG4787@2 NA|NA|NA N Belongs to the flagella basal body rod proteins family HFDCGJPN_00223 1101195.Meth11DRAFT_1536 1.3e-121 442.6 Nitrosomonadales flgG GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009279,GO:0009288,GO:0009424,GO:0009425,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044462,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MVMA@1224,2KKBI@206350,2VH7A@28216,COG4786@1,COG4786@2 NA|NA|NA N flagellar basal-body rod protein FlgG HFDCGJPN_00224 1101195.Meth11DRAFT_1537 1.2e-67 263.1 Nitrosomonadales flgH ko:K02393 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1RDEY@1224,2KP68@206350,2VRIC@28216,COG2063@1,COG2063@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation HFDCGJPN_00225 1101195.Meth11DRAFT_1538 8.1e-149 533.5 Nitrosomonadales flgI GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009288,GO:0009425,GO:0009987,GO:0033554,GO:0040011,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071973,GO:0097588 ko:K02394 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MVKW@1224,2KKTZ@206350,2VJAZ@28216,COG1706@1,COG1706@2 NA|NA|NA N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation HFDCGJPN_00226 666681.M301_1713 2.4e-98 365.5 Nitrosomonadales flgJ GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 3.5.1.28 ko:K01448,ko:K02395 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko02035,ko03036 Bacteria 1MX2W@1224,2KMDM@206350,2VH35@28216,COG1705@1,COG1705@2,COG3951@1,COG3951@2 NA|NA|NA N TIGRFAM flagellar rod assembly protein muramidase FlgJ HFDCGJPN_00227 1165096.ARWF01000001_gene913 4.4e-171 608.2 Nitrosomonadales flgK GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0044085,GO:0044780,GO:0044781,GO:0070925,GO:0071840 ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MV2M@1224,2KKC0@206350,2VH02@28216,COG1256@1,COG1256@2 NA|NA|NA N Belongs to the flagella basal body rod proteins family HFDCGJPN_00228 666681.M301_1715 5.4e-79 301.2 Nitrosomonadales flgL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1PJUJ@1224,2KMFX@206350,2VM4I@28216,COG1344@1,COG1344@2 NA|NA|NA N TIGRFAM flagellar hook-associated protein 3 HFDCGJPN_00229 583345.Mmol_1254 1.5e-236 826.2 Nitrosomonadales ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2KNK8@206350,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA T SMART chemotaxis sensory transducer HFDCGJPN_00231 582744.Msip34_0813 6.6e-144 517.7 Nitrosomonadales ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2KKQK@206350,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA NT PFAM chemotaxis sensory transducer HFDCGJPN_00232 582744.Msip34_1410 9e-58 229.6 Nitrosomonadales tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1MUS2@1224,2KM9T@206350,2VHSG@28216,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome HFDCGJPN_00233 582744.Msip34_1409 2.2e-121 441.8 Nitrosomonadales pyrH GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0033862,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 Bacteria 1MV3N@1224,2KKZ6@206350,2VH8A@28216,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP HFDCGJPN_00234 582744.Msip34_1408 1.2e-81 309.3 Nitrosomonadales frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1N66T@1224,2KM1Y@206350,2VIUA@28216,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another HFDCGJPN_00235 582744.Msip34_1407 9.2e-109 399.8 Nitrosomonadales uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1MVP1@1224,2KKTC@206350,2VH2E@28216,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids HFDCGJPN_00236 265072.Mfla_1525 5.6e-78 297.7 Nitrosomonadales cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iJN746.PP_1596,iSDY_1059.SDY_0191 Bacteria 1MWSV@1224,2KMNS@206350,2VMM0@28216,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family HFDCGJPN_00237 582744.Msip34_1405 4.8e-152 544.3 Nitrosomonadales dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 1MU4G@1224,2KM2I@206350,2VHJY@28216,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) HFDCGJPN_00238 582744.Msip34_1404 6.1e-159 567.4 Nitrosomonadales rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 ko:K04771,ko:K11749 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU91@1224,2KKRG@206350,2VHBW@28216,COG0750@1,COG0750@2 NA|NA|NA M Peptidase family M50 HFDCGJPN_00239 582744.Msip34_1403 0.0 1312.4 Nitrosomonadales bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 1MU0D@1224,2KMAN@206350,2VHTX@28216,COG4775@1,COG4775@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HFDCGJPN_00240 582744.Msip34_1402 9.7e-65 253.1 Nitrosomonadales skp GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564 ko:K06142 ko00000 Bacteria 1RD8X@1224,2KMK3@206350,2VRZI@28216,COG2825@1,COG2825@2 NA|NA|NA M Belongs to the skp family HFDCGJPN_00241 582744.Msip34_1401 2.5e-96 359.0 Nitrosomonadales lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 ic_1306.c0216 Bacteria 1MUX6@1224,2KKFR@206350,2VHJR@28216,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell HFDCGJPN_00242 582744.Msip34_1400 3e-78 297.7 Nitrosomonadales fabZ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 iJN746.PP_1602 Bacteria 1RH2T@1224,2KMMW@206350,2VRKQ@28216,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs HFDCGJPN_00243 1132855.KB913035_gene1440 1e-110 406.4 Nitrosomonadales lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 iIT341.HP1375 Bacteria 1MUHQ@1224,2KM0C@206350,2VHDG@28216,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell HFDCGJPN_00244 582744.Msip34_1398 3.4e-155 554.7 Nitrosomonadales lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478,iIT341.HP0867 Bacteria 1MVBI@1224,2KMDQ@206350,2VIBP@28216,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell HFDCGJPN_00245 666681.M301_1326 1.9e-74 285.4 Nitrosomonadales rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1RA65@1224,2KMKS@206350,2VQ06@28216,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids HFDCGJPN_00246 265072.Mfla_1515 1.1e-84 319.7 Nitrosomonadales rsmI_1 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1RARW@1224,2KKRK@206350,2VQ34@28216,COG0313@1,COG0313@2 NA|NA|NA H PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase HFDCGJPN_00247 1502770.JQMG01000001_gene2005 4.8e-199 700.7 Nitrosomonadales Bacteria 1QCVP@1224,2KKQV@206350,2VNEJ@28216,COG5316@1,COG5316@2 NA|NA|NA S Domain of unknown function (DUF4139) HFDCGJPN_00248 582744.Msip34_1394 3.8e-70 271.2 Nitrosomonadales maf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030312,GO:0044464,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1RDA9@1224,2KMKG@206350,2VQUQ@28216,COG0424@1,COG0424@2 NA|NA|NA D TIGRFAM maf protein HFDCGJPN_00249 1236959.BAMT01000001_gene1630 1.9e-288 998.0 Nitrosomonadales oadA 2.3.1.12,4.1.1.3,6.4.1.1,6.4.1.7 ko:K00627,ko:K01571,ko:K01960,ko:K20140 ko00010,ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map01230 M00173,M00307,M00620 R00209,R00217,R00344,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 iJN746.PP_5346,iLJ478.TM0128 Bacteria 1QTTG@1224,2KKYX@206350,2VKZP@28216,COG0511@1,COG0511@2,COG5016@1,COG5016@2 NA|NA|NA CI TIGRFAM oxaloacetate decarboxylase alpha subunit HFDCGJPN_00250 582744.Msip34_1392 1.1e-256 892.1 Nitrosomonadales pycA 6.3.4.14,6.3.4.6,6.4.1.1,6.4.1.2 ko:K01941,ko:K01959,ko:K01961 ko00020,ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376,M00620 R00344,R00742,R00774,R04385 RC00040,RC00253,RC00367,RC00378 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4H@1224,2KME4@206350,2WH9U@28216,COG0439@1,COG0439@2 NA|NA|NA I PFAM Carbamoyl-phosphate synthase L chain HFDCGJPN_00251 582744.Msip34_1391 2.5e-38 165.2 Nitrosomonadales yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1PGKW@1224,2KNA5@206350,2VUIG@28216,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 HFDCGJPN_00252 1101195.Meth11DRAFT_1221 4.2e-28 129.8 Nitrosomonadales rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1N6RF@1224,2KN4T@206350,2VVP5@28216,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family HFDCGJPN_00253 582744.Msip34_1389 1.3e-161 575.9 Nitrosomonadales plsX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695 Bacteria 1MVM3@1224,2KMA0@206350,2VI25@28216,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA HFDCGJPN_00254 582744.Msip34_1388 7.5e-148 530.0 Nitrosomonadales fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360 Bacteria 1MU9N@1224,2KM2A@206350,2VI2A@28216,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids HFDCGJPN_00255 1236959.BAMT01000001_gene1636 2.2e-128 465.3 Nitrosomonadales fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MV6N@1224,2KKJT@206350,2VJF7@28216,COG0331@1,COG0331@2 NA|NA|NA I TIGRFAM malonyl CoA-acyl carrier protein transacylase HFDCGJPN_00256 582744.Msip34_1386 3.5e-100 371.3 Nitrosomonadales Bacteria 1MU6X@1224,2KMAU@206350,2VJ3S@28216,COG1028@1,COG1028@2 NA|NA|NA IQ TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase HFDCGJPN_00257 582744.Msip34_1385 4.8e-32 143.3 Nitrosomonadales acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1MZ4P@1224,2KN5P@206350,2VTZH@28216,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis HFDCGJPN_00258 582744.Msip34_1384 6.6e-213 746.5 Nitrosomonadales fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Bacteria 1MU1X@1224,2KMFU@206350,2VI6I@28216,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP HFDCGJPN_00259 666681.M301_1340 4e-81 308.1 Nitrosomonadales pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Bacteria 1MZAK@1224,2KMJW@206350,2VRAS@28216,COG0115@1,COG0115@2 NA|NA|NA EH PFAM Aminotransferase class IV HFDCGJPN_00260 582744.Msip34_1382 7.2e-125 453.8 Nitrosomonadales mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 ko:K07082 ko00000 Bacteria 1MUQF@1224,2KKWE@206350,2VHD4@28216,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation HFDCGJPN_00261 1502770.JQMG01000001_gene2019 2.2e-76 292.0 Nitrosomonadales tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV9C@1224,2KKXE@206350,2VQ24@28216,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis HFDCGJPN_00262 582744.Msip34_1380 1.1e-93 350.1 Nitrosomonadales holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MY1W@1224,2KKRR@206350,2VNED@28216,COG0470@1,COG0470@2 NA|NA|NA L TIGRFAM DNA polymerase III, delta HFDCGJPN_00263 666681.M301_1349 3.7e-47 194.1 Nitrosomonadales pilZ ko:K02676 ko00000,ko02035,ko02044 Bacteria 1RGWZ@1224,2KN0B@206350,2VT2B@28216,COG3215@1,COG3215@2 NA|NA|NA NU PFAM type IV pilus assembly PilZ HFDCGJPN_00264 265072.Mfla_1497 2.8e-113 414.8 Nitrosomonadales ycfH GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1MUC0@1224,2KKZF@206350,2VHCT@28216,COG0084@1,COG0084@2 NA|NA|NA L TIGRFAM hydrolase, TatD family HFDCGJPN_00265 666681.M301_1351 1.9e-101 375.6 Nitrosomonadales phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 1MVJH@1224,2KMIB@206350,2VKJK@28216,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain HFDCGJPN_00266 582744.Msip34_1376 8e-24 116.7 Nitrosomonadales Bacteria 1P2VS@1224,2FF6I@1,2KN4X@206350,2W46G@28216,3474I@2 NA|NA|NA HFDCGJPN_00267 1101195.Meth11DRAFT_2356 6.5e-98 363.6 Nitrosomonadales queC 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 R09978 RC00959 ko00000,ko00001,ko01000,ko03016 iAF987.Gmet_3075 Bacteria 1MU5V@1224,2KKW4@206350,2VHY3@28216,COG0603@1,COG0603@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) HFDCGJPN_00268 582744.Msip34_2394 2.2e-35 154.5 Nitrosomonadales rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1MZCT@1224,2KN3F@206350,2VTYP@28216,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family HFDCGJPN_00269 582744.Msip34_2393 3.5e-59 234.6 Nitrosomonadales rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1MWQR@1224,2KMQK@206350,2VQ0H@28216,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes HFDCGJPN_00270 265072.Mfla_2332 2.1e-105 388.7 Nitrosomonadales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1MUN1@1224,2KKEG@206350,2VHPY@28216,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family HFDCGJPN_00271 1132855.KB913035_gene568 4e-55 220.7 Nitrosomonadales rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RH3A@1224,2KMTA@206350,2VR2S@28216,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site HFDCGJPN_00272 582744.Msip34_2390 5.5e-43 180.6 Nitrosomonadales ogt 2.1.1.63 ko:K00567,ko:K10778 ko00000,ko01000,ko03000,ko03400 Bacteria 1N2YQ@1224,2KN1I@206350,2VU5R@28216,COG0350@1,COG0350@2 NA|NA|NA L PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding HFDCGJPN_00273 1132855.KB913035_gene570 8.1e-128 463.4 Nitrosomonadales xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1MVNF@1224,2KM9Y@206350,2VIHD@28216,COG4974@1,COG4974@2 NA|NA|NA L TIGRFAM tyrosine recombinase XerD HFDCGJPN_00274 1121035.AUCH01000007_gene446 5.8e-48 197.6 Rhodocyclales acrR ko:K03577,ko:K18135 ko01501,map01501 M00647 ko00000,ko00001,ko00002,ko03000 Bacteria 1N659@1224,2KX9V@206389,2VS47@28216,COG1309@1,COG1309@2 NA|NA|NA K MAATS-type transcriptional repressor, C-terminal region HFDCGJPN_00275 1000565.METUNv1_02701 1.1e-66 260.8 Rhodocyclales cmeA ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MU78@1224,2KVSS@206389,2VINC@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_00276 1123393.KB891316_gene1945 0.0 1349.7 Hydrogenophilales ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 Bacteria 1KR9P@119069,1MU48@1224,2VHFI@28216,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family HFDCGJPN_00277 265072.Mfla_2008 6.8e-70 270.0 Nitrosomonadales rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5E@1224,2KM8Y@206350,2VJAD@28216,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily HFDCGJPN_00278 1165096.ARWF01000001_gene187 4.5e-139 500.7 Nitrosomonadales rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334,iSDY_1059.SDY_2206,iSF_1195.SF2102,iSFxv_1172.SFxv_2338,iS_1188.S2225 Bacteria 1MU0X@1224,2KM7G@206350,2VHA6@28216,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis HFDCGJPN_00279 1005048.CFU_0808 2.8e-75 288.1 Oxalobacteraceae rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1R9YD@1224,2VQ02@28216,472YX@75682,COG1898@1,COG1898@2 NA|NA|NA G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose HFDCGJPN_00280 1165096.ARWF01000001_gene189 4.7e-99 367.9 Nitrosomonadales rfbD 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUXM@1224,2KKK4@206350,2VI50@28216,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose HFDCGJPN_00281 582744.Msip34_1443 2.4e-69 268.1 Nitrosomonadales queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1RETG@1224,2KMK9@206350,2VRBN@28216,COG0720@1,COG0720@2 NA|NA|NA H PFAM 6-pyruvoyl tetrahydropterin synthase HFDCGJPN_00282 582744.Msip34_1441 5.8e-115 420.6 Nitrosomonadales rsgA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675 Bacteria 1MUEF@1224,2KM0D@206350,2VINY@28216,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit HFDCGJPN_00283 582744.Msip34_1440 6.8e-34 149.8 Nitrosomonadales Bacteria 1N71Z@1224,2KN7Q@206350,2VWE5@28216,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c HFDCGJPN_00284 265072.Mfla_1474 1e-189 669.5 Nitrosomonadales htpX_2 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 1MUXT@1224,2KM5K@206350,2VI1Y@28216,COG0501@1,COG0501@2 NA|NA|NA O CAAX prenyl protease N-terminal, five membrane helices HFDCGJPN_00285 582744.Msip34_2134 2.9e-76 291.2 Nitrosomonadales bfr 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 1RCW7@1224,2KMPX@206350,2VPZP@28216,COG2193@1,COG2193@2 NA|NA|NA P Ferritin-like domain HFDCGJPN_00286 582744.Msip34_2135 9.5e-67 259.6 Nitrosomonadales bfrA 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 1RD4Y@1224,2KMN1@206350,2VQG7@28216,COG2193@1,COG2193@2 NA|NA|NA P Ferritin-like domain HFDCGJPN_00287 582744.Msip34_2136 5e-302 1043.5 Nitrosomonadales fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1MU08@1224,2KM5C@206350,2VJSM@28216,COG2217@1,COG2217@2,COG2608@1,COG2608@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC HFDCGJPN_00288 582744.Msip34_2137 1.3e-40 172.9 Nitrosomonadales fixH Bacteria 1N6AR@1224,2KNHT@206350,2VU84@28216,COG5456@1,COG5456@2 NA|NA|NA P YtkA-like HFDCGJPN_00289 582744.Msip34_0036 2.1e-103 382.5 Nitrosomonadales algZ 2.7.13.3 ko:K08082 ko02020,map02020 M00493 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MXVQ@1224,2KM4E@206350,2VH9S@28216,COG2972@1,COG2972@2 NA|NA|NA T PFAM histidine kinase HFDCGJPN_00290 582744.Msip34_0037 3.2e-224 784.3 Nitrosomonadales argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUTU@1224,2KMF6@206350,2VH47@28216,COG0165@1,COG0165@2 NA|NA|NA E TIGRFAM argininosuccinate lyase HFDCGJPN_00291 666681.M301_0077 6.8e-53 215.3 Betaproteobacteria ko:K02404 ko00000,ko02035 Bacteria 1NBJC@1224,2VX30@28216,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV HFDCGJPN_00292 1112274.KI911560_gene1150 2.1e-91 342.0 Nitrosomonadales yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 Bacteria 1MU76@1224,2KM1J@206350,2VHBB@28216,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound HFDCGJPN_00293 265072.Mfla_1878 4e-66 257.7 Nitrosomonadales ispZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K06190 ko00000 Bacteria 1NWIZ@1224,2KMUD@206350,2VRHB@28216,COG2917@1,COG2917@2 NA|NA|NA D probably involved in intracellular septation HFDCGJPN_00294 1236959.BAMT01000003_gene540 3.4e-38 164.1 Nitrosomonadales yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K05527,ko:K09780 ko00000,ko03000 Bacteria 1MZ9Z@1224,2KN2X@206350,2VUM7@28216,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain HFDCGJPN_00295 1502770.JQMG01000001_gene156 6.7e-27 126.3 Nitrosomonadales bolA ko:K05527,ko:K09780 ko00000,ko03000 Bacteria 1MZG5@1224,2KN9P@206350,2VVNP@28216,COG0271@1,COG0271@2 NA|NA|NA T Belongs to the BolA IbaG family HFDCGJPN_00296 582744.Msip34_0956 1.9e-129 468.8 Proteobacteria eat ko:K16238 ko00000,ko02000 2.A.3.5 Bacteria 1QUC6@1224,COG1113@1,COG1113@2 NA|NA|NA E amino acid HFDCGJPN_00297 709032.Sulku_0131 1.6e-38 165.6 Epsilonproteobacteria atzF 3.5.1.4,3.5.1.54 ko:K01426,ko:K01457 ko00220,ko00330,ko00360,ko00380,ko00627,ko00643,ko00791,ko01100,ko01120,map00220,map00330,map00360,map00380,map00627,map00643,map00791,map01100,map01120 R00005,R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025,RC02756 ko00000,ko00001,ko01000 Bacteria 1MUVQ@1224,2YMS5@29547,42PK7@68525,COG0154@1,COG0154@2 NA|NA|NA J Amidase HFDCGJPN_00298 666681.M301_2217 4.3e-189 667.5 Nitrosomonadales atzF 3.5.1.4,3.5.1.54 ko:K01426,ko:K01457 ko00220,ko00330,ko00360,ko00380,ko00627,ko00643,ko00791,ko01100,ko01120,map00220,map00330,map00360,map00380,map00627,map00643,map00791,map01100,map01120 R00005,R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025,RC02756 ko00000,ko00001,ko01000 Bacteria 1MUVQ@1224,2KKBX@206350,2VIG3@28216,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) HFDCGJPN_00299 666681.M301_2218 8.2e-09 65.5 Nitrosomonadales uca 6.3.4.14,6.3.4.6,6.4.1.1,6.4.1.2 ko:K01941,ko:K01959,ko:K01961 ko00020,ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376,M00620 R00344,R00742,R00774,R04385 RC00040,RC00253,RC00367,RC00378 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4H@1224,2KNIP@206350,2WGI2@28216,COG0439@1,COG0439@2,COG1984@1,COG1984@2,COG2049@1,COG2049@2 NA|NA|NA C Carbamoyl-phosphate synthetase large chain domain protein HFDCGJPN_00300 1088721.NSU_1794 6.3e-08 63.2 Alphaproteobacteria Bacteria 1NVHG@1224,28PWR@1,2URVD@28211,2ZCGZ@2 NA|NA|NA HFDCGJPN_00302 582744.Msip34_2802 1.2e-204 719.2 Nitrosomonadales hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 1MUY5@1224,2KKPE@206350,2VHK9@28216,COG0001@1,COG0001@2 NA|NA|NA H PFAM Aminotransferase class-III HFDCGJPN_00303 582744.Msip34_2801 7.5e-60 236.9 Nitrosomonadales thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDSU@1224,2KMSI@206350,2VSR5@28216,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) HFDCGJPN_00304 582744.Msip34_2800 5.2e-129 467.2 Nitrosomonadales thiD 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9J@1224,2KM6A@206350,2VKD2@28216,COG0351@1,COG0351@2 NA|NA|NA H PFAM Phosphomethylpyrimidine kinase HFDCGJPN_00305 1235457.C404_22215 3.4e-24 116.7 Burkholderiaceae rubA ko:K03618 ko00000 Bacteria 1KA31@119060,1N731@1224,2VVP4@28216,COG1773@1,COG1773@2 NA|NA|NA C PFAM Rubredoxin-type Fe(Cys)4 protein HFDCGJPN_00307 582744.Msip34_2782 6.6e-134 483.4 Nitrosomonadales thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 1N0N5@1224,2KKDX@206350,2VJ8T@28216,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S HFDCGJPN_00308 1236959.BAMT01000007_gene2715 8.4e-50 203.0 Nitrosomonadales apaG ko:K06195 ko00000 Bacteria 1MZ2Z@1224,2KMYJ@206350,2VSPE@28216,COG2967@1,COG2967@2 NA|NA|NA P ApaG domain HFDCGJPN_00309 582744.Msip34_2780 1.6e-150 539.3 Nitrosomonadales mltA GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K08304 ko00000,ko01000,ko01011 GH102 iECABU_c1320.ECABU_c30840 Bacteria 1MXD4@1224,2KM9X@206350,2VHBF@28216,COG2821@1,COG2821@2 NA|NA|NA M MltA specific insert domain HFDCGJPN_00310 265072.Mfla_2634 6.1e-100 370.5 Nitrosomonadales ygiD 1.13.11.8 ko:K04100,ko:K15777 ko00362,ko00624,ko00627,ko00965,ko01120,map00362,map00624,map00627,map00965,map01120 R01632,R03550,R04280,R08836,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 Bacteria 1MXJZ@1224,2KM6Z@206350,2VIC3@28216,COG3384@1,COG3384@2 NA|NA|NA S Catalytic LigB subunit of aromatic ring-opening dioxygenase HFDCGJPN_00311 1387312.BAUS01000010_gene126 4.2e-41 174.1 Nitrosomonadales ko:K15977 ko00000 Bacteria 1MZVP@1224,2KN69@206350,2VSDZ@28216,COG2259@1,COG2259@2 NA|NA|NA S SURF4 family HFDCGJPN_00312 265072.Mfla_2632 1.6e-112 412.5 Nitrosomonadales Bacteria 1MW16@1224,2KP4Z@206350,2VQR6@28216,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain HFDCGJPN_00313 582744.Msip34_2774 9.6e-161 573.2 Nitrosomonadales lplT ko:K08227 ko00000,ko02000 2.A.1.42 Bacteria 1QTWR@1224,2KNK7@206350,2WGR1@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily HFDCGJPN_00314 1502770.JQMG01000001_gene778 0.0 1104.7 Nitrosomonadales aas GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008779,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019752,GO:0031224,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 iEC042_1314.EC042_3034 Bacteria 1MWDY@1224,2KMIC@206350,2VK7T@28216,COG0204@1,COG0204@2,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase HFDCGJPN_00315 582744.Msip34_2772 2e-33 148.3 Nitrosomonadales ko:K03892 ko00000,ko03000 Bacteria 1MZPS@1224,2KN4B@206350,2VUHJ@28216,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor HFDCGJPN_00316 582744.Msip34_2771 2e-95 355.5 Nitrosomonadales Bacteria 1R9YQ@1224,2KNJG@206350,2VHC5@28216,COG4340@1,COG4340@2 NA|NA|NA S 2OG-Fe dioxygenase HFDCGJPN_00317 666681.M301_1401 1.4e-280 971.8 Nitrosomonadales Bacteria 1MY59@1224,2KKQG@206350,2VKNY@28216,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease HFDCGJPN_00318 666681.M301_1402 1.2e-52 212.6 Betaproteobacteria yjbI ko:K06886 ko00000 Bacteria 1RH21@1224,2VUYA@28216,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin HFDCGJPN_00319 666681.M301_1403 7e-171 606.7 Nitrosomonadales Bacteria 1MZX4@1224,2KNJK@206350,2VZKU@28216,COG0697@1,COG0697@2 NA|NA|NA EG spore germination HFDCGJPN_00320 666681.M301_1404 1.8e-26 125.2 Nitrosomonadales Bacteria 1PJUX@1224,2A8WP@1,2KP2J@206350,2W86R@28216,30Y02@2 NA|NA|NA HFDCGJPN_00322 640081.Dsui_1207 2.1e-58 234.2 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KW9H@206389,2VHFJ@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00323 1502770.JQMG01000001_gene1719 5.3e-61 240.7 Nitrosomonadales bcpB 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 1MWJP@1224,2KNTH@206350,2VQ0B@28216,COG1225@1,COG1225@2 NA|NA|NA O Redoxin HFDCGJPN_00325 272568.GDI0521 5.6e-62 244.2 Rhodospirillales alkA 2.1.1.63,3.2.2.21 ko:K00567,ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MX9C@1224,2JX9Y@204441,2UA13@28211,COG0122@1,COG0122@2 NA|NA|NA L endonuclease III HFDCGJPN_00326 204773.HEAR1490 3.2e-73 281.6 Oxalobacteraceae alkB GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008198,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016705,GO:0016706,GO:0032451,GO:0033554,GO:0034641,GO:0035510,GO:0035511,GO:0035513,GO:0035515,GO:0035552,GO:0035553,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043734,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044728,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0070579,GO:0070988,GO:0070989,GO:0071704,GO:0080111,GO:0090304,GO:0140098,GO:1901360 1.14.11.33 ko:K03919 ko00000,ko01000,ko03400 Bacteria 1N5HB@1224,2VHNU@28216,4745M@75682,COG3145@1,COG3145@2 NA|NA|NA L repair protein HFDCGJPN_00327 666681.M301_1406 6.8e-159 567.0 Nitrosomonadales ribB 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU8P@1224,2KNK2@206350,2VH6S@28216,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H 3,4-dihydroxy-2-butanone 4-phosphate synthase HFDCGJPN_00328 666681.M301_0615 3.7e-108 397.9 Nitrosomonadales folE2 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1B@1224,2KKMR@206350,2VIC9@28216,COG1469@1,COG1469@2 NA|NA|NA S Converts GTP to 7,8-dihydroneopterin triphosphate HFDCGJPN_00329 666681.M301_1408 6.4e-21 106.7 Betaproteobacteria Bacteria 1N7QE@1224,2E7VB@1,2VWXI@28216,332A5@2 NA|NA|NA HFDCGJPN_00330 666681.M301_1409 1.6e-56 226.1 Betaproteobacteria Bacteria 1NAPM@1224,2E5NH@1,2VVYQ@28216,330DA@2 NA|NA|NA HFDCGJPN_00331 1026882.MAMP_01167 9.5e-42 176.4 Gammaproteobacteria Bacteria 1MZ3K@1224,1SFMR@1236,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein HFDCGJPN_00332 666681.M301_1410 3.4e-234 817.4 Proteobacteria ko:K16238 ko00000,ko02000 2.A.3.5 Bacteria 1MXNJ@1224,COG0531@1,COG0531@2 NA|NA|NA E amino acid HFDCGJPN_00333 1026882.MAMP_01171 1e-09 68.6 Bacteria Bacteria 2ENR6@1,33EH6@2 NA|NA|NA HFDCGJPN_00334 666681.M301_1412 1.1e-33 149.4 Betaproteobacteria Bacteria 1N21G@1224,2E0FK@1,2VU8B@28216,32W1S@2 NA|NA|NA HFDCGJPN_00335 666681.M301_1413 1.6e-24 118.6 Betaproteobacteria Bacteria 1NBAP@1224,2BYQZ@1,2VYS3@28216,3300Y@2 NA|NA|NA HFDCGJPN_00337 265072.Mfla_0459 1.1e-151 542.7 Nitrosomonadales gltA 1.4.1.13,1.4.1.14,1.4.7.1,2.1.1.21 ko:K00265,ko:K00284,ko:K22083 ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R01586,R10086 RC00006,RC00010,RC00554,RC02799 ko00000,ko00001,ko01000 Bacteria 1MU7B@1224,2KKH0@206350,2VKQG@28216,COG0069@1,COG0069@2 NA|NA|NA E Belongs to the glutamate synthase family HFDCGJPN_00338 1132855.KB913035_gene2452 1.2e-23 115.5 Nitrosomonadales Bacteria 1N05X@1224,2DNY9@1,2KN9A@206350,2VW4T@28216,32ZS2@2 NA|NA|NA S Protein of unknown function (DUF2805) HFDCGJPN_00339 1236959.BAMT01000011_gene3182 1.7e-118 432.2 Nitrosomonadales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1MVE3@1224,2KM6W@206350,2VHEW@28216,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins HFDCGJPN_00340 582744.Msip34_0372 0.0 1133.6 Nitrosomonadales ilvD 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1259 Bacteria 1MUTQ@1224,2KMH6@206350,2VH5Q@28216,COG0129@1,COG0129@2 NA|NA|NA E Belongs to the IlvD Edd family HFDCGJPN_00341 666681.M301_0383 2.6e-153 548.1 Nitrosomonadales yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 1Q7VN@1224,2KKG9@206350,2VKZK@28216,COG0676@1,COG0676@2 NA|NA|NA G Belongs to the glucose-6-phosphate 1-epimerase family HFDCGJPN_00342 582744.Msip34_1549 4.6e-50 205.7 Nitrosomonadales fimV ko:K07288,ko:K08086 ko00000 Bacteria 1MXV7@1224,2KMD2@206350,2VHX1@28216,COG3170@1,COG3170@2 NA|NA|NA NU pilus assembly protein FimV HFDCGJPN_00343 1123487.KB892835_gene3484 7.1e-161 573.9 Rhodocyclales Bacteria 1MVK3@1224,2KVDZ@206389,2VH7S@28216,COG0397@1,COG0397@2 NA|NA|NA S Belongs to the UPF0061 (SELO) family HFDCGJPN_00344 582744.Msip34_0374 5e-43 180.3 Nitrosomonadales ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1N6UN@1224,2KMZ0@206350,2VW1Y@28216,COG4654@1,COG4654@2 NA|NA|NA C PFAM cytochrome c, class I HFDCGJPN_00345 697282.Mettu_3556 1.8e-190 672.2 Methylococcales ko:K03294 ko00000 2.A.3.2 Bacteria 1MXNJ@1224,1RMKV@1236,1XE0I@135618,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease HFDCGJPN_00346 1236959.BAMT01000011_gene3192 6e-155 553.5 Nitrosomonadales hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Bacteria 1MWMF@1224,2KKQ4@206350,2VIN4@28216,COG0408@1,COG0408@2 NA|NA|NA H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX HFDCGJPN_00347 582744.Msip34_0379 7.3e-63 246.9 Nitrosomonadales tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07479,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1MVPM@1224,2KKJM@206350,2VIFT@28216,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine HFDCGJPN_00348 582744.Msip34_0380 2.9e-208 731.1 Nitrosomonadales purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 Bacteria 1MUAH@1224,2KKHI@206350,2VH9J@28216,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family HFDCGJPN_00349 582744.Msip34_0381 4.1e-268 930.2 Nitrosomonadales purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iEcHS_1320.EcHS_A4240,iPC815.YPO3728 Bacteria 1MUDQ@1224,2KKHT@206350,2VJPX@28216,COG0138@1,COG0138@2 NA|NA|NA F TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase HFDCGJPN_00350 265072.Mfla_0350 1e-26 125.6 Nitrosomonadales fis GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03557,ko:K07712 ko02020,ko05111,map02020,map05111 M00497 ko00000,ko00001,ko00002,ko02022,ko03000,ko03036,ko03400 Bacteria 1N7MJ@1224,2KNBI@206350,2VVQK@28216,COG2901@1,COG2901@2 NA|NA|NA K Bacterial regulatory protein, Fis family HFDCGJPN_00351 582744.Msip34_0383 9.7e-145 519.6 Nitrosomonadales dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K05540 ko00000,ko01000,ko03016 Bacteria 1MV5V@1224,2KKMM@206350,2VHBP@28216,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines HFDCGJPN_00352 582744.Msip34_1993 1.6e-125 455.7 Nitrosomonadales rpoH ko:K03089 ko00000,ko03021 Bacteria 1MVWR@1224,2KKPY@206350,2VI91@28216,COG0568@1,COG0568@2 NA|NA|NA K RNA polymerase sigma factor, sigma-70 family HFDCGJPN_00353 265072.Mfla_0701 2e-18 97.8 Nitrosomonadales ccoS Bacteria 1PJS9@1224,2KNZZ@206350,2W85G@28216,COG3197@1,COG3197@2 NA|NA|NA P Cytochrome oxidase maturation protein cbb3-type HFDCGJPN_00354 1165096.ARWF01000001_gene960 0.0 1088.2 Nitrosomonadales Bacteria 1MXBK@1224,2KKJN@206350,2VKA1@28216,COG0699@1,COG0699@2 NA|NA|NA S Dynamin family HFDCGJPN_00355 582744.Msip34_1997 2.3e-55 221.5 Nitrosomonadales Bacteria 1MZ5M@1224,2KMR5@206350,2VR9K@28216,COG3536@1,COG3536@2 NA|NA|NA S Protein of unknown function (DUF971) HFDCGJPN_00356 1236959.BAMT01000004_gene917 2.8e-118 431.4 Nitrosomonadales ubiE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0040007,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Bacteria 1MX8I@1224,2KME1@206350,2VHBM@28216,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) HFDCGJPN_00357 265072.Mfla_0697 1.1e-53 216.5 Nitrosomonadales yigP GO:0006082,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0019752,GO:0032150,GO:0042180,GO:0042181,GO:0043436,GO:0043648,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046417,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 ko:K03690 ko00000 Bacteria 1N314@1224,2KMY8@206350,2VU2B@28216,COG3165@1,COG3165@2 NA|NA|NA S SCP-2 sterol transfer family HFDCGJPN_00358 265072.Mfla_0696 1.4e-223 782.3 Nitrosomonadales ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 ko:K03688 ko00000 iYL1228.KPN_04331 Bacteria 1MU1Z@1224,2KKPI@206350,2VJ07@28216,COG0661@1,COG0661@2 NA|NA|NA H Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis HFDCGJPN_00359 748247.AZKH_0492 9.9e-216 756.1 Rhodocyclales putP ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 ko00000,ko00001,ko02000 2.A.21,2.A.21.8 Bacteria 1MUBI@1224,2KUVM@206389,2VHA8@28216,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family HFDCGJPN_00360 1165096.ARWF01000001_gene967 7.1e-115 420.2 Nitrosomonadales fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVM5@1224,2KKWR@206350,2VI10@28216,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates HFDCGJPN_00361 582744.Msip34_2004 3.5e-107 394.8 Nitrosomonadales Bacteria 1N41X@1224,2E2GR@1,2KKWG@206350,2VUN3@28216,32XKS@2 NA|NA|NA S Domain of unknown function (DUF4340) HFDCGJPN_00362 582744.Msip34_2005 3.5e-215 754.2 Nitrosomonadales gldG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUXW@1224,2KM0A@206350,2VMDE@28216,COG3225@1,COG3225@2 NA|NA|NA N ABC-type uncharacterized transport system HFDCGJPN_00363 582744.Msip34_2006 6.8e-104 383.6 Nitrosomonadales yxlG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1NZZ9@1224,2KP9X@206350,2VRRA@28216,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein HFDCGJPN_00364 582744.Msip34_2007 2.9e-144 518.1 Nitrosomonadales 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 Bacteria 1MUX3@1224,2KM5I@206350,2VJ2B@28216,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter HFDCGJPN_00365 265072.Mfla_0681 1.8e-192 679.1 Nitrosomonadales Bacteria 1MYB8@1224,2KMD8@206350,2VI6C@28216,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat HFDCGJPN_00366 582744.Msip34_2009 5.7e-48 197.6 Nitrosomonadales lolB GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 ko:K02494 ko00000 Bacteria 1N02T@1224,2KN1T@206350,2VUIR@28216,COG3017@1,COG3017@2 NA|NA|NA M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein HFDCGJPN_00367 265072.Mfla_0679 4.2e-92 344.7 Nitrosomonadales ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1MVU3@1224,2KKVP@206350,2VHK3@28216,COG1947@1,COG1947@2 NA|NA|NA I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol HFDCGJPN_00369 582744.Msip34_2011 3.5e-153 547.7 Nitrosomonadales prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 1MW21@1224,2KKZQ@206350,2VHU0@28216,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) HFDCGJPN_00370 1236959.BAMT01000004_gene893 1.1e-91 342.8 Nitrosomonadales ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 1RDH0@1224,2KKVD@206350,2VQNU@28216,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance HFDCGJPN_00371 1236959.BAMT01000004_gene892 9.1e-80 303.1 Nitrosomonadales pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1MX1P@1224,2KKY6@206350,2VKKJ@28216,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis HFDCGJPN_00372 1101195.Meth11DRAFT_1989 1e-229 803.5 Nitrosomonadales Bacteria 1MU2C@1224,2KKWS@206350,2VH3V@28216,COG5001@1,COG5001@2 NA|NA|NA T PFAM EAL domain HFDCGJPN_00374 1165096.ARWF01000001_gene1415 4.1e-26 124.8 Nitrosomonadales Bacteria 1PJIU@1224,2A8M6@1,2KN7K@206350,2W80M@28216,30XPK@2 NA|NA|NA HFDCGJPN_00375 1502770.JQMG01000001_gene1021 2.3e-49 202.2 Nitrosomonadales Bacteria 1N8K0@1224,2E6RE@1,2KMZY@206350,2VWUF@28216,331BH@2 NA|NA|NA HFDCGJPN_00376 666681.M301_0147 1.5e-34 152.5 Nitrosomonadales Bacteria 1R6PQ@1224,2CG4C@1,2KKMA@206350,2VHKG@28216,2Z8MQ@2 NA|NA|NA HFDCGJPN_00377 582744.Msip34_1077 0.0 1912.5 Nitrosomonadales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 1MUEQ@1224,2KM5A@206350,2VI3R@28216,COG1643@1,COG1643@2 NA|NA|NA L TIGRFAM ATP-dependent helicase HrpA HFDCGJPN_00378 1123393.KB891316_gene1604 1.8e-141 508.8 Hydrogenophilales Bacteria 1KRZ3@119069,1R7HC@1224,2W90N@28216,COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_00379 1122236.KB905141_gene1162 3.9e-66 257.7 Nitrosomonadales yqhA Bacteria 1RANN@1224,2KMMY@206350,2VK3P@28216,COG2862@1,COG2862@2 NA|NA|NA S UPF0114 protein HFDCGJPN_00380 582744.Msip34_1072 5.6e-123 447.2 Nitrosomonadales pcm 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1NMMQ@1224,2KM1V@206350,2VH3B@28216,COG2518@1,COG2518@2 NA|NA|NA O Methyltransferase domain HFDCGJPN_00381 264198.Reut_B5335 9.3e-57 227.3 Burkholderiaceae brkB ko:K07058 ko00000 Bacteria 1KH2N@119060,1R9UY@1224,2VJYA@28216,COG1295@1,COG1295@2 NA|NA|NA S ribonuclease BN HFDCGJPN_00382 582744.Msip34_1074 3.6e-51 207.6 Nitrosomonadales Bacteria 1RI37@1224,2BZ0G@1,2KMWR@206350,2VT46@28216,32R44@2 NA|NA|NA HFDCGJPN_00383 582744.Msip34_0784 1e-65 256.1 Nitrosomonadales Bacteria 1MZIG@1224,2KP59@206350,2VK4J@28216,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold HFDCGJPN_00384 1165096.ARWF01000001_gene1718 1.6e-32 146.0 Nitrosomonadales GO:0005575,GO:0005576,GO:0005615,GO:0044421 Bacteria 1RD06@1224,2KN64@206350,2VSZ8@28216,COG2335@1,COG2335@2 NA|NA|NA M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. HFDCGJPN_00385 1236959.BAMT01000006_gene352 3.3e-183 647.9 Nitrosomonadales ntrX Bacteria 1MU0N@1224,2KKE1@206350,2VKD8@28216,COG2204@1,COG2204@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_00386 265072.Mfla_0182 6.1e-167 594.0 Nitrosomonadales ntrY Bacteria 1MWKZ@1224,2KKR4@206350,2VIDI@28216,COG5000@1,COG5000@2 NA|NA|NA T histidine kinase HAMP region domain protein HFDCGJPN_00387 1112274.KI911560_gene2518 1.9e-221 775.4 Betaproteobacteria Bacteria 1R6K6@1224,2DB9H@1,2W0C2@28216,2Z7WW@2 NA|NA|NA HFDCGJPN_00388 582744.Msip34_2422 2.7e-46 192.2 Nitrosomonadales glxC 2.1.1.21 ko:K22082,ko:K22083 ko00680,ko01120,map00680,map01120 R01586 RC00554 ko00000,ko00001,ko01000 Bacteria 1MUUQ@1224,2KMHN@206350,2VHP7@28216,COG2218@1,COG2218@2 NA|NA|NA C PFAM glutamate synthase alpha subunit domain protein HFDCGJPN_00389 582744.Msip34_2423 4.4e-142 510.8 Nitrosomonadales glxB 2.1.1.21 ko:K22081 ko00680,ko01120,map00680,map01120 R01586 RC00554 ko00000,ko00001,ko01000 Bacteria 1MWHP@1224,2KKHA@206350,2VM3C@28216,COG0034@1,COG0034@2 NA|NA|NA F Glutamine amidotransferases class-II HFDCGJPN_00390 666681.M301_1417 1.6e-220 771.9 Nitrosomonadales glnT 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1MUGQ@1224,2KKXC@206350,2VJ0X@28216,COG0174@1,COG0174@2 NA|NA|NA E PFAM glutamine synthetase catalytic region HFDCGJPN_00391 666681.M301_1418 5.5e-65 254.2 Nitrosomonadales ygfZ 1.5.3.1,2.1.2.10 ko:K00302,ko:K00305,ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R00610,R01221,R02300,R04125 RC00022,RC00060,RC00069,RC00183,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1N2I3@1224,2KMXD@206350,2VVMU@28216,COG0404@1,COG0404@2 NA|NA|NA E Sarcosine oxidase, gamma subunit family HFDCGJPN_00392 666681.M301_1419 0.0 1331.2 Nitrosomonadales 1.5.3.1,2.1.2.10 ko:K00302,ko:K00305,ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R00610,R01221,R02300,R04125 RC00022,RC00060,RC00069,RC00183,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVEK@1224,2KKZ2@206350,2VK5U@28216,COG0404@1,COG0404@2,COG0446@1,COG0446@2 NA|NA|NA E glycine cleavage T protein (aminomethyl transferase) HFDCGJPN_00393 666681.M301_1420 4.6e-32 143.7 Nitrosomonadales 1.5.3.1 ko:K00304 ko00260,ko01100,map00260,map01100 R00610 RC00060,RC00557 ko00000,ko00001,ko01000 Bacteria 1NA4N@1224,2KP93@206350,2VX6V@28216,COG4311@1,COG4311@2 NA|NA|NA E PFAM Sarcosine oxidase delta subunit heterotetrameric HFDCGJPN_00394 582744.Msip34_2428 4.4e-209 733.8 Nitrosomonadales 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 R00610 RC00060,RC00557 ko00000,ko00001,ko01000 Bacteria 1MVM6@1224,2KMA5@206350,2VKCE@28216,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase HFDCGJPN_00395 265072.Mfla_0437 7e-81 307.0 Nitrosomonadales Bacteria 1MVQY@1224,2KKK6@206350,2VI57@28216,COG1396@1,COG1396@2,COG3837@1,COG3837@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain HFDCGJPN_00396 582744.Msip34_2430 2.2e-49 201.8 Nitrosomonadales Bacteria 1N2EC@1224,2KMY9@206350,2VUTI@28216,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain HFDCGJPN_00397 420662.Mpe_A0675 2.8e-76 291.6 Betaproteobacteria 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 1RDHA@1224,2VQG4@28216,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase HFDCGJPN_00398 666681.M301_2683 1.7e-98 365.5 Nitrosomonadales hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K03665 ko00000,ko03009 Bacteria 1MUA0@1224,2KKFI@206350,2VHVU@28216,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis HFDCGJPN_00399 1236959.BAMT01000002_gene2249 4.2e-138 497.7 Nitrosomonadales surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 1MVB3@1224,2KKDR@206350,2VHHS@28216,COG0760@1,COG0760@2 NA|NA|NA M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation HFDCGJPN_00400 582744.Msip34_0577 1.6e-110 406.0 Nitrosomonadales pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_0056 Bacteria 1MX5W@1224,2KKW8@206350,2VJN0@28216,COG1995@1,COG1995@2 NA|NA|NA H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) HFDCGJPN_00401 261292.Nit79A3_3382 7.2e-90 337.8 Nitrosomonadales vieA Bacteria 1NC9X@1224,2WGSU@28216,374RA@32003,COG0784@1,COG0784@2,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_00402 1349767.GJA_597 9e-121 441.8 Oxalobacteraceae Bacteria 1NRP8@1224,2VGZQ@28216,472D0@75682,COG0642@1,COG2205@2,COG5002@1,COG5002@2 NA|NA|NA T PhoQ Sensor HFDCGJPN_00403 1122236.KB905142_gene447 1.3e-113 416.0 Nitrosomonadales ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1MVNU@1224,2KKX9@206350,2VH15@28216,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits HFDCGJPN_00404 582744.Msip34_0575 2.5e-110 404.8 Nitrosomonadales adk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_1506 Bacteria 1MXCZ@1224,2KKQZ@206350,2VH1C@28216,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism HFDCGJPN_00405 666681.M301_2578 6.8e-89 333.6 Nitrosomonadales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0421 Bacteria 1MUPV@1224,2KKHQ@206350,2VH7F@28216,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) HFDCGJPN_00406 398579.Spea_3432 1.1e-40 172.9 Shewanellaceae ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1RHH6@1224,1S74Q@1236,2QBT4@267890,COG1463@1,COG1463@2 NA|NA|NA Q Protein of unknown function (DUF3465) HFDCGJPN_00407 59538.XP_005976933.1 5.3e-107 394.0 Bilateria Metazoa 38FIR@33154,3BUYE@33208,3DFBG@33213,COG0134@1,KOG4201@2759 NA|NA|NA E Indole-3-glycerol phosphate synthase HFDCGJPN_00408 1101195.Meth11DRAFT_2505 6.1e-177 626.7 Nitrosomonadales hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MWMW@1224,2KMIF@206350,2VHC6@28216,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family HFDCGJPN_00409 1163617.SCD_n02938 4.6e-47 194.9 Betaproteobacteria ycgR Bacteria 1MX00@1224,2VQEK@28216,COG5581@1,COG5581@2 NA|NA|NA M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility HFDCGJPN_00410 265072.Mfla_2463 7.8e-58 230.3 Nitrosomonadales Bacteria 1RFTH@1224,2KMNQ@206350,2VJC9@28216,COG2413@1,COG2413@2 NA|NA|NA HFDCGJPN_00411 582744.Msip34_2507 0.0 1185.2 Nitrosomonadales mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1MU5A@1224,2KKG3@206350,2VHXF@28216,COG5009@1,COG5009@2 NA|NA|NA M TIGRFAM penicillin-binding protein, 1A family HFDCGJPN_00412 582744.Msip34_2506 1.3e-151 542.7 Nitrosomonadales pilM ko:K02662 ko00000,ko02035,ko02044 Bacteria 1MX8P@1224,2KKWF@206350,2VH6W@28216,COG4972@1,COG4972@2 NA|NA|NA NU TIGRFAM type IV pilus assembly protein PilM HFDCGJPN_00413 1236959.BAMT01000002_gene1920 6.2e-57 227.3 Nitrosomonadales pilN ko:K02663 ko00000,ko02035,ko02044 Bacteria 1RF1S@1224,2KMWG@206350,2VN9T@28216,COG3166@1,COG3166@2 NA|NA|NA NU Fimbrial assembly protein (PilN) HFDCGJPN_00414 1236959.BAMT01000002_gene1921 3e-73 281.6 Nitrosomonadales pilO ko:K02664 ko00000,ko02035,ko02044 Bacteria 1RBGW@1224,2KKDE@206350,2VH68@28216,COG3167@1,COG3167@2 NA|NA|NA NU PFAM Pilus assembly protein PilO HFDCGJPN_00415 582744.Msip34_2503 3.3e-54 218.0 Nitrosomonadales pilP ko:K02664,ko:K02665 ko00000,ko02035,ko02044 Bacteria 1RI6V@1224,2KMV4@206350,2VSVR@28216,COG3168@1,COG3168@2 NA|NA|NA NU PFAM Pilus assembly protein PilP HFDCGJPN_00416 265072.Mfla_2457 2.4e-279 968.0 Nitrosomonadales pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 ko:K02507,ko:K02666 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1QTT6@1224,2KKNT@206350,2VHY4@28216,COG4796@1,COG4796@2 NA|NA|NA U type II and III secretion system protein HFDCGJPN_00417 582744.Msip34_2501 3.3e-65 254.6 Nitrosomonadales aroK 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUFJ@1224,2KMSN@206350,2VRDN@28216,COG0703@1,COG0703@2 NA|NA|NA E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate HFDCGJPN_00418 582744.Msip34_2500 2.5e-160 571.6 Nitrosomonadales aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iIT341.HP0283,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 Bacteria 1MUBK@1224,2KMCZ@206350,2VHXR@28216,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) HFDCGJPN_00419 582744.Msip34_2499 9.5e-158 563.1 Nitrosomonadales dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 1MVQ2@1224,2KKU8@206350,2VI7B@28216,COG0232@1,COG0232@2 NA|NA|NA F Belongs to the dGTPase family. Type 2 subfamily HFDCGJPN_00420 582744.Msip34_2498 6.3e-133 480.7 Nitrosomonadales Bacteria 1P7S0@1224,2KM1P@206350,2VNY2@28216,COG3203@1,COG3203@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane HFDCGJPN_00421 582744.Msip34_2496 8e-86 324.3 Proteobacteria Bacteria 1R12Q@1224,COG0457@1,COG0457@2 NA|NA|NA S Macrocin-O-methyltransferase (TylF) HFDCGJPN_00422 582744.Msip34_2495 3.4e-242 844.0 Nitrosomonadales glnG GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 ko:K07712 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KM9J@206350,2VHSB@28216,COG2204@1,COG2204@2 NA|NA|NA T TIGRFAM nitrogen regulation protein NR(I) HFDCGJPN_00423 582744.Msip34_2494 4.7e-170 604.0 Nitrosomonadales glnL GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07708,ko:K07710 ko02020,map02020 M00497,M00500 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MVN6@1224,2KKW6@206350,2VJN7@28216,COG3852@1,COG3852@2 NA|NA|NA T PFAM ATP-binding region ATPase domain protein HFDCGJPN_00424 1236959.BAMT01000002_gene1933 1.3e-26 126.3 Nitrosomonadales Bacteria 1PSUJ@1224,2EBVX@1,2KN2R@206350,2VXJY@28216,335VA@2 NA|NA|NA S Domain of unknown function (DUF4124) HFDCGJPN_00425 1122236.KB905145_gene2554 9.1e-259 899.0 Nitrosomonadales glnA GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016853,GO:0016866,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0034022,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050486,GO:0050896,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.4.4.3,6.3.1.2 ko:K01915,ko:K20712 ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253,R06988,R09284 RC00010,RC01754,RC02798 ko00000,ko00001,ko01000,ko04147 iJN746.PP_5046 Bacteria 1MUGQ@1224,2KKT7@206350,2VHYE@28216,COG0174@1,COG0174@2 NA|NA|NA E TIGRFAM glutamine synthetase, type I HFDCGJPN_00426 582744.Msip34_2491 5.6e-61 240.4 Nitrosomonadales Bacteria 1REHH@1224,2KMSD@206350,2VR3P@28216,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain HFDCGJPN_00427 582744.Msip34_2490 2.3e-100 372.1 Nitrosomonadales aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVH4@1224,2KKRT@206350,2VHHC@28216,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) HFDCGJPN_00428 582744.Msip34_2489 3.3e-97 361.3 Nitrosomonadales mtgA 2.4.1.129,3.4.16.4 ko:K03814,ko:K05365,ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1RDAQ@1224,2KMBM@206350,2VHW8@28216,COG0744@1,COG0744@2 NA|NA|NA M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors HFDCGJPN_00429 582744.Msip34_2488 2.4e-102 378.6 Nitrosomonadales Bacteria 1RCW6@1224,2KMPB@206350,2VMUW@28216,COG1639@1,COG1639@2 NA|NA|NA T signal transduction protein HFDCGJPN_00430 1236959.BAMT01000002_gene1938 0.0 1695.6 Nitrosomonadales uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1MW0W@1224,2KKD7@206350,2VIJE@28216,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate HFDCGJPN_00431 1163617.SCD_n00653 1e-129 470.3 Betaproteobacteria yajR Bacteria 1MVSH@1224,2VITN@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily HFDCGJPN_00432 583345.Mmol_2131 1.1e-65 256.1 Nitrosomonadales ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1RCWT@1224,2KMPH@206350,2VR2Z@28216,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism HFDCGJPN_00433 582744.Msip34_2454 2.1e-33 147.9 Nitrosomonadales Bacteria 1N6Q9@1224,2KN44@206350,2VTX5@28216,COG2331@1,COG2331@2 NA|NA|NA S regulatory protein, FmdB family HFDCGJPN_00434 582744.Msip34_2453 9.8e-96 356.3 Nitrosomonadales Bacteria 1MWT5@1224,2KKZ9@206350,2VH65@28216,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) HFDCGJPN_00435 582744.Msip34_2452 0.0 1170.2 Nitrosomonadales aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN678.aspS,iSFV_1184.SFV_1868 Bacteria 1MUXB@1224,2KM0Z@206350,2VHKQ@28216,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) HFDCGJPN_00436 1132855.KB913035_gene447 5.9e-62 243.8 Nitrosomonadales apt 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1MVZ6@1224,2KMKX@206350,2VI7G@28216,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis HFDCGJPN_00437 582744.Msip34_2449 5.3e-59 233.8 Nitrosomonadales nudB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 ko:K01515,ko:K03574,ko:K03801,ko:K08310 ko00230,ko00785,ko00790,ko01100,map00230,map00785,map00790,map01100 M00126 R01054,R04638,R07766,R07769 RC00002,RC00039,RC00992,RC02867 ko00000,ko00001,ko00002,ko01000,ko03400 iSFV_1184.SFV_1867,iSF_1195.SF1875,iSFxv_1172.SFxv_2099,iS_1188.S1941,iY75_1357.Y75_RS09795,iYL1228.KPN_02379 Bacteria 1RH6N@1224,2KMQJ@206350,2VR3U@28216,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain HFDCGJPN_00438 697282.Mettu_3502 2e-64 253.1 Methylococcales 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 1PGPR@1224,1RX1U@1236,1XGJY@135618,COG3290@1,COG3290@2,COG3447@1,COG3447@2,COG3614@1,COG3614@2,COG3920@1,COG3920@2 NA|NA|NA T Histidine kinase HFDCGJPN_00439 1122236.KB905143_gene72 4.7e-58 231.1 Betaproteobacteria ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 1QZ0F@1224,2WHZP@28216,COG3707@1,COG3707@2 NA|NA|NA T ANTAR HFDCGJPN_00440 1163617.SCD_n00429 2e-186 659.4 Betaproteobacteria ydcR GO:0000302,GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008081,GO:0008150,GO:0009987,GO:0010035,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042578,GO:0050896,GO:0051716,GO:0052621,GO:0070887,GO:0071111,GO:0071241,GO:0071731,GO:0071732,GO:0097366,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.7.65 ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Bacteria 1MU2C@1224,2VH3V@28216,COG3300@1,COG3300@2,COG5001@1,COG5001@2 NA|NA|NA T MHYT domain HFDCGJPN_00441 583345.Mmol_1256 1.6e-196 693.0 Betaproteobacteria mcpY ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA NT chemotaxis HFDCGJPN_00442 1116472.MGMO_36c00010 2.3e-207 728.0 Gammaproteobacteria Bacteria 1ND1J@1224,1RQ15@1236,COG4447@1,COG4447@2 NA|NA|NA S protein related to plant photosystem II stability assembly factor HFDCGJPN_00443 1101195.Meth11DRAFT_2409 0.0 1112.4 Nitrosomonadales 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 1QTTJ@1224,2KKG8@206350,2VHB9@28216,COG1529@1,COG1529@2 NA|NA|NA C PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding HFDCGJPN_00444 1101195.Meth11DRAFT_2410 4.4e-130 471.1 Nitrosomonadales xdhC2 ko:K07402 ko00000 Bacteria 1MXKU@1224,2KM36@206350,2VHIK@28216,COG1975@1,COG1975@2 NA|NA|NA O XdhC and CoxI family HFDCGJPN_00445 1165096.ARWF01000001_gene1702 2e-47 195.7 Nitrosomonadales ygfJ 2.7.7.76 ko:K07141 ko00790,map00790 R11582 ko00000,ko00001,ko01000 Bacteria 1MW0X@1224,2KMYU@206350,2VSIN@28216,COG2068@1,COG2068@2 NA|NA|NA S MobA-like NTP transferase domain HFDCGJPN_00446 1132855.KB913035_gene1498 5.8e-202 710.3 Nitrosomonadales ko:K07576 ko00000 Bacteria 1MUDD@1224,2KKTT@206350,2VHFX@28216,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain HFDCGJPN_00447 666681.M301_0609 4.3e-20 103.6 Bacteria ko:K09794 ko00000 Bacteria COG2841@1,COG2841@2 NA|NA|NA S Protein of unknown function (DUF465) HFDCGJPN_00448 1387312.BAUS01000007_gene2186 1.1e-60 239.2 Nitrosomonadales Bacteria 1R2D3@1224,2KNCX@206350,2WIAP@28216,COG5485@1,COG5485@2 NA|NA|NA S SnoaL-like polyketide cyclase HFDCGJPN_00449 1026882.MAMP_00698 1.5e-27 128.6 Thiotrichales Bacteria 1MZ6N@1224,1S6R7@1236,463T9@72273,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix HFDCGJPN_00450 666681.M301_1896 1.8e-62 245.4 Nitrosomonadales tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5 ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K11991 ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223 RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000,ko01002,ko01011,ko03016 Bacteria 1RGU0@1224,2KMTZ@206350,2VR60@28216,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) HFDCGJPN_00451 265072.Mfla_1839 4e-204 718.0 Nitrosomonadales tgpA 2.3.2.13 ko:K22452 ko00000,ko01000 Bacteria 1MWCE@1224,2KKPG@206350,2VHZP@28216,COG1305@1,COG1305@2 NA|NA|NA E Domain of unknown function (DUF3488) HFDCGJPN_00452 666681.M301_1894 6e-97 360.9 Nitrosomonadales Bacteria 1R3QD@1224,2KKPC@206350,2VN9P@28216,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 HFDCGJPN_00453 265072.Mfla_1837 4.5e-126 457.6 Nitrosomonadales moxR ko:K03924 ko00000,ko01000 Bacteria 1MUFN@1224,2KKI1@206350,2VKJJ@28216,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) HFDCGJPN_00454 582744.Msip34_0976 2.4e-59 235.0 Betaproteobacteria Bacteria 1N7CX@1224,2WFFX@28216,COG3431@1,COG3431@2 NA|NA|NA S Phosphate-starvation-inducible E HFDCGJPN_00455 582744.Msip34_0977 3.8e-125 454.5 Nitrosomonadales allS_2 Bacteria 1MZTA@1224,2KM9B@206350,2VJTZ@28216,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family HFDCGJPN_00456 265072.Mfla_1833 1.5e-89 335.9 Nitrosomonadales ko:K06911 ko00000 Bacteria 1MVSW@1224,2KM4D@206350,2VHPA@28216,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family HFDCGJPN_00457 1101195.Meth11DRAFT_1717 4.2e-82 310.8 Nitrosomonadales Bacteria 1MW7N@1224,2KKSS@206350,2VRZD@28216,COG0655@1,COG0655@2 NA|NA|NA S Flavodoxin domain HFDCGJPN_00458 582744.Msip34_0980 2.3e-75 288.5 Nitrosomonadales yceI Bacteria 1R9XD@1224,2KMQ0@206350,2VYPK@28216,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family HFDCGJPN_00459 582744.Msip34_0981 1.7e-164 585.5 Nitrosomonadales morB ko:K10680 ko00633,ko01120,map00633,map01120 R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 Bacteria 1MVIX@1224,2KKF6@206350,2VH2S@28216,COG1902@1,COG1902@2 NA|NA|NA C PFAM NADH flavin oxidoreductase NADH oxidase HFDCGJPN_00460 583345.Mmol_0734 4.2e-89 334.3 Nitrosomonadales tdsD Bacteria 1RA6E@1224,2KKHC@206350,2VSIM@28216,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family HFDCGJPN_00461 1502770.JQMG01000001_gene98 1.1e-54 219.2 Nitrosomonadales 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 1QVCY@1224,2KMUK@206350,2WGQT@28216,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin HFDCGJPN_00462 748247.AZKH_3431 3e-16 91.7 Rhodocyclales 6.1.1.16 ko:K01884 ko00970,map00970 M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MU7T@1224,2KW9H@206389,2VHFJ@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00463 265072.Mfla_1386 3.4e-105 387.9 Nitrosomonadales dapC 2.6.1.11,2.6.1.17 ko:K00821,ko:K14267 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MWS8@1224,2KKF4@206350,2VIEP@28216,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II HFDCGJPN_00464 666681.M301_1485 7.7e-126 456.8 Nitrosomonadales miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1MUB2@1224,2KKC6@206350,2VHEP@28216,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) HFDCGJPN_00465 582744.Msip34_0445 4.3e-46 190.3 Nitrosomonadales gcs2 Bacteria 1MUAD@1224,2KM45@206350,2VI55@28216,COG2308@1,COG2308@2 NA|NA|NA S Circularly permuted ATP-grasp type 2 HFDCGJPN_00466 265072.Mfla_0392 5.9e-129 467.2 Nitrosomonadales MA20_32425 Bacteria 1MVZK@1224,2KKR6@206350,2VIB5@28216,COG2307@1,COG2307@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. HFDCGJPN_00467 582744.Msip34_0447 6.7e-89 334.0 Nitrosomonadales MA20_32430 Bacteria 1MVMI@1224,2KKMX@206350,2VH3S@28216,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues HFDCGJPN_00468 1122236.KB905143_gene220 9.5e-204 716.1 Nitrosomonadales 5.1.99.1 ko:K05606,ko:K17315 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko02010,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map02010 M00373,M00375,M00376,M00605,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.24,3.A.1.1.30 Bacteria 1R5AJ@1224,2KKMU@206350,2W11Y@28216,COG3185@1,COG3185@2 NA|NA|NA E 4-Hydroxyphenylpyruvate dioxygenase HFDCGJPN_00471 316067.Geob_3119 4.9e-26 124.4 Deltaproteobacteria ko:K09924 ko00000 Bacteria 1N7UG@1224,2WSZB@28221,42XKS@68525,COG3184@1,COG3184@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2059) HFDCGJPN_00472 582744.Msip34_0227 1.1e-87 330.1 Nitrosomonadales eamA1 Bacteria 1MYHQ@1224,2KM25@206350,2WFCK@28216,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family HFDCGJPN_00473 582744.Msip34_0449 0.0 1088.2 Nitrosomonadales ydcP ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUQG@1224,2KKFW@206350,2VHHU@28216,COG0826@1,COG0826@2 NA|NA|NA O Collagenase HFDCGJPN_00474 1122236.KB905142_gene429 3.1e-157 561.6 Nitrosomonadales ko:K06076 ko00000,ko02000 1.B.9 Bacteria 1MV7W@1224,2KM6M@206350,2VKVT@28216,COG2067@1,COG2067@2 NA|NA|NA I PFAM membrane protein involved in aromatic hydrocarbon degradation HFDCGJPN_00475 1132855.KB913035_gene2406 6.5e-139 501.1 Nitrosomonadales 2.7.7.65 ko:K18967 ko00000,ko01000,ko02000 9.B.34.1.1 Bacteria 1P29Y@1224,2KKHM@206350,2W170@28216,COG2199@1,COG2199@2 NA|NA|NA T Diverse 7TM receptor transmembrane region HFDCGJPN_00476 491952.Mar181_2464 3e-70 272.3 Oceanospirillales yvaC Bacteria 1QW9U@1224,1T41N@1236,1XNNN@135619,COG1289@1,COG1289@2 NA|NA|NA S Fusaric acid resistance protein-like HFDCGJPN_00477 640081.Dsui_1001 3.9e-86 325.5 Betaproteobacteria Bacteria 1Q18B@1224,2CEP7@1,2W6A4@28216,2ZEAF@2 NA|NA|NA HFDCGJPN_00478 640081.Dsui_1000 1.9e-114 419.5 Bacteria Bacteria COG1721@1,COG1721@2 NA|NA|NA E protein (some members contain a von Willebrand factor type A (vWA) domain HFDCGJPN_00479 640081.Dsui_0999 3.3e-124 451.4 Rhodocyclales ko:K03924 ko00000,ko01000 Bacteria 1MUFN@1224,2KW6R@206389,2VKJJ@28216,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) HFDCGJPN_00480 1165096.ARWF01000001_gene1159 1.7e-130 472.6 Nitrosomonadales pldA 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 Bacteria 1PC8I@1224,2KNB2@206350,2VMT8@28216,COG2829@1,COG2829@2 NA|NA|NA M Phospholipase A1 HFDCGJPN_00481 582744.Msip34_2304 1.7e-156 558.9 Nitrosomonadales tas 1.1.1.91 ko:K05882 ko00000,ko01000 Bacteria 1MV2Y@1224,2KMA6@206350,2VI7D@28216,COG0667@1,COG0667@2 NA|NA|NA C PFAM aldo keto reductase HFDCGJPN_00482 400682.PAC_15708150 8.3e-39 166.4 Opisthokonta Opisthokonta 2D16N@1,2SGX8@2759,3ASE6@33154 NA|NA|NA HFDCGJPN_00483 1165096.ARWF01000001_gene1049 3.2e-135 488.0 Nitrosomonadales dedA_2 Bacteria 1R6F1@1224,2KKCX@206350,2VMW2@28216,COG0586@1,COG0586@2,COG0607@1,COG0607@2 NA|NA|NA P SNARE associated Golgi protein HFDCGJPN_00484 582744.Msip34_2682 5.3e-108 397.1 Nitrosomonadales Bacteria 1MU5N@1224,2KP6U@206350,2VJFI@28216,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family HFDCGJPN_00485 1132855.KB913035_gene2416 4.9e-104 384.0 Nitrosomonadales yhhW_2 ko:K06911 ko00000 Bacteria 1MVSW@1224,2KNQA@206350,2VHPA@28216,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family HFDCGJPN_00486 666681.M301_0859 1.3e-125 456.1 Nitrosomonadales Bacteria 1MZTA@1224,2KNQK@206350,2VJTZ@28216,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family HFDCGJPN_00488 1123393.KB891317_gene2207 1.6e-85 322.8 Hydrogenophilales mscS GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03442 ko00000,ko02000 1.A.23.2 Bacteria 1KSDQ@119069,1N596@1224,2VQ9J@28216,COG0668@1,COG0668@2 NA|NA|NA M Conserved TM helix HFDCGJPN_00489 582744.Msip34_0340 1.1e-108 399.8 Nitrosomonadales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MVMI@1224,2KKHH@206350,2VH3S@28216,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues HFDCGJPN_00490 1101195.Meth11DRAFT_1165 1.9e-116 425.6 Nitrosomonadales MA20_16190 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MX5P@1224,2KM2V@206350,2VJEU@28216,COG2307@1,COG2307@2,COG2308@1,COG2308@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. HFDCGJPN_00491 1499967.BAYZ01000086_gene5162 1.3e-44 187.6 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups HFDCGJPN_00493 643562.Daes_1990 2.4e-86 325.5 Desulfovibrionales Bacteria 1Q3GM@1224,2MA7I@213115,2WP46@28221,42SZ6@68525,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM Short-chain dehydrogenase reductase SDR HFDCGJPN_00494 324925.Ppha_0534 2.4e-66 258.8 Bacteria ptmB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.43,2.7.7.82 ko:K00983,ko:K18431 ko00520,ko01100,map00520,map01100 R01117,R04215,R10182 RC00152 ko00000,ko00001,ko01000 Bacteria COG1083@1,COG1083@2 NA|NA|NA M cytidylyl-transferase HFDCGJPN_00495 324925.Ppha_0533 1e-70 273.9 Bacteria ptmF 2.7.7.82 ko:K18431 ko00520,map00520 R10182 RC00152 ko00000,ko00001,ko01000 Bacteria COG0673@1,COG0673@2 NA|NA|NA S inositol 2-dehydrogenase activity HFDCGJPN_00496 1200792.AKYF01000027_gene386 4.7e-80 304.3 Bacilli ubiE2 Bacteria 1UP4M@1239,4HWTZ@91061,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family HFDCGJPN_00497 243365.CV_4029 1.2e-50 207.2 Betaproteobacteria Bacteria 1RG1R@1224,2WH73@28216,COG2348@1,COG2348@2 NA|NA|NA V Acetyltransferase (GNAT) domain HFDCGJPN_00498 243365.CV_4030 2.5e-120 438.7 Betaproteobacteria ptmE Bacteria 1MUYJ@1224,2VNAZ@28216,COG0517@1,COG0517@2,COG1208@1,COG1208@2 NA|NA|NA JM PFAM Nucleotidyl transferase HFDCGJPN_00499 243365.CV_4031 4.5e-120 438.0 Neisseriales neuB GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576 2.5.1.101,2.5.1.56 ko:K01654,ko:K18430 ko00520,ko01100,map00520,map01100 R01804,R04435,R10304 RC00159 ko00000,ko00001,ko01000 Bacteria 1MWG3@1224,2KQ5D@206351,2VHMH@28216,COG2089@1,COG2089@2 NA|NA|NA M SAF HFDCGJPN_00500 243365.CV_4032 9.8e-51 207.6 Betaproteobacteria Bacteria 1R5SK@1224,2VYXY@28216,COG0399@1,COG0399@2 NA|NA|NA M UDP-4-amino-4-deoxy-L-arabinose aminotransferase HFDCGJPN_00501 309807.SRU_0602 3.2e-116 425.2 Bacteroidetes neuC GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576 3.2.1.184,5.1.3.14 ko:K01791,ko:K18429 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R10187 RC00005,RC00288,RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 4NFTG@976,COG0381@1,COG0381@2 NA|NA|NA M UDP-N-acetylglucosamine 2-epimerase HFDCGJPN_00502 1120973.AQXL01000124_gene2380 2e-155 555.4 Bacilli 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1TPDH@1239,4HBZ8@91061,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family HFDCGJPN_00503 1316936.K678_09418 3.4e-159 567.8 Rhodospirillales 4.2.1.46,5.1.3.2 ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1QUEV@1224,2JZ25@204441,2TW46@28211,COG0451@1,COG0451@2 NA|NA|NA M NmrA-like family HFDCGJPN_00504 331678.Cphamn1_0373 1.9e-165 589.3 Chlorobi ko:K02022,ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1FDNB@1090,COG1132@1,COG1132@2 NA|NA|NA V PFAM ABC transporter transmembrane region HFDCGJPN_00505 1286106.MPL1_01583 2.9e-39 167.9 Thiotrichales ko:K18996 ko00000,ko03032 Bacteria 1N0TY@1224,1SADN@1236,463BK@72273,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator HFDCGJPN_00506 265072.Mfla_1266 5.9e-133 480.7 Nitrosomonadales splB Bacteria 1MW0H@1224,2KMEW@206350,2VIYE@28216,COG1533@1,COG1533@2 NA|NA|NA L Elongator protein 3, MiaB family, Radical SAM HFDCGJPN_00507 265072.Mfla_1265 2.2e-45 188.3 Nitrosomonadales hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04762 ko00000,ko03110 Bacteria 1MZR6@1224,2KMTC@206350,2VTY8@28216,COG1188@1,COG1188@2 NA|NA|NA J PFAM RNA-binding S4 domain protein HFDCGJPN_00508 582744.Msip34_1729 6.2e-182 644.0 Nitrosomonadales lon1 3.4.21.53 ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1MWGB@1224,2KKIX@206350,2VJ54@28216,COG1067@1,COG1067@2 NA|NA|NA O Belongs to the peptidase S16 family HFDCGJPN_00509 1165096.ARWF01000001_gene471 5.3e-34 150.6 Nitrosomonadales wbpV 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX2J@1224,2KKJX@206350,2VJHC@28216,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD-dependent epimerase dehydratase HFDCGJPN_00510 1165096.ARWF01000001_gene470 1.4e-96 359.8 Betaproteobacteria wbpL 2.7.8.33,2.7.8.35 ko:K02851,ko:K13007 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 1MWYW@1224,2VNAG@28216,COG0472@1,COG0472@2 NA|NA|NA M PFAM Glycosyl transferase family 4 HFDCGJPN_00511 265072.Mfla_1278 4.7e-234 817.4 Nitrosomonadales capD 4.2.1.115 ko:K15894 ko00520,map00520 R09697 RC02609 ko00000,ko00001,ko01000 Bacteria 1MWKY@1224,2KM3V@206350,2VHGF@28216,COG1086@1,COG1086@2 NA|NA|NA GM PFAM polysaccharide biosynthesis protein CapD HFDCGJPN_00512 1236959.BAMT01000009_gene3439 9.4e-129 466.5 Nitrosomonadales galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV5F@1224,2KM2M@206350,2VH00@28216,COG1210@1,COG1210@2 NA|NA|NA M PFAM Nucleotidyl transferase HFDCGJPN_00513 582744.Msip34_1723 8.1e-67 260.0 Nitrosomonadales hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 Bacteria 1NRT8@1224,2KMTN@206350,2VRM9@28216,COG0634@1,COG0634@2 NA|NA|NA F Phosphoribosyl transferase domain HFDCGJPN_00514 582744.Msip34_1568 1.9e-234 818.5 Nitrosomonadales 2.7.13.3 ko:K07675 ko02020,map02020 M00473 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWPN@1224,2KM0S@206350,2VNHG@28216,COG4585@1,COG4585@2 NA|NA|NA T histidine kinase HAMP region domain protein HFDCGJPN_00515 582744.Msip34_1567 9.3e-102 376.3 Nitrosomonadales gacA ko:K02282,ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 Bacteria 1MWGM@1224,2KKFM@206350,2VQ32@28216,COG2197@1,COG2197@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_00516 582744.Msip34_1566 4.9e-44 184.5 Nitrosomonadales Bacteria 1PJIF@1224,2A8KR@1,2KN5W@206350,2W80D@28216,30XP5@2 NA|NA|NA HFDCGJPN_00517 582744.Msip34_1565 6.8e-108 397.1 Nitrosomonadales ko:K15270 ko00000,ko02000 2.A.7.3.7 Bacteria 1MZXM@1224,2KMF0@206350,2VK90@28216,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family HFDCGJPN_00518 748247.AZKH_4524 2e-41 178.7 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KZTM@206389,2VNQ5@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00519 582744.Msip34_1564 1.3e-172 612.5 Nitrosomonadales alcE 1.14.15.7 ko:K00479,ko:K00499 ko00260,map00260 R07409 RC00087 ko00000,ko00001,ko01000 Bacteria 1MWXW@1224,2KKI4@206350,2VH18@28216,COG4638@1,COG4638@2 NA|NA|NA P Ring hydroxylating alpha subunit (catalytic domain) HFDCGJPN_00521 1101195.Meth11DRAFT_1030 4.8e-61 240.7 Nitrosomonadales Bacteria 1RFIZ@1224,2KMP8@206350,2VRTS@28216,COG3748@1,COG3748@2 NA|NA|NA S Urate oxidase N-terminal HFDCGJPN_00522 582744.Msip34_1561 1.3e-186 659.1 Nitrosomonadales argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MV3C@1224,2KM17@206350,2VHEB@28216,COG4992@1,COG4992@2 NA|NA|NA E PFAM Aminotransferase class-III HFDCGJPN_00523 582744.Msip34_1560 1.6e-163 582.0 Nitrosomonadales argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUFM@1224,2KKJ5@206350,2VIVG@28216,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline HFDCGJPN_00524 1101195.Meth11DRAFT_1033 2.6e-222 777.7 Nitrosomonadales argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1MV0Y@1224,2KKKM@206350,2VJ7Z@28216,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily HFDCGJPN_00525 1163617.SCD_n02094 2.7e-21 107.8 Betaproteobacteria ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1N759@1224,2VVPU@28216,COG4095@1,COG4095@2 NA|NA|NA S PQ loop repeat HFDCGJPN_00526 582744.Msip34_1557 1.8e-50 204.9 Nitrosomonadales ppnP 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1MZ8N@1224,2KMXP@206350,2VSCI@28216,COG3123@1,COG3123@2 NA|NA|NA S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions HFDCGJPN_00527 582744.Msip34_1555 1.5e-75 288.9 Nitrosomonadales yajQ GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K09767 ko00000 Bacteria 1RDTF@1224,2KKK8@206350,2VPZU@28216,COG1666@1,COG1666@2 NA|NA|NA S Belongs to the UPF0234 family HFDCGJPN_00528 1101195.Meth11DRAFT_1036 1.3e-244 852.0 Nitrosomonadales leuC 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MVYR@1224,2KMDA@206350,2VHSH@28216,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate HFDCGJPN_00530 582744.Msip34_1552 2.6e-104 384.8 Nitrosomonadales leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1MVXB@1224,2KM7B@206350,2VIJC@28216,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate HFDCGJPN_00531 582744.Msip34_1551 1.4e-182 645.6 Nitrosomonadales leuB GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082 Bacteria 1MUH4@1224,2KMFH@206350,2VH2M@28216,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate HFDCGJPN_00532 1132855.KB913035_gene1717 1.3e-188 665.6 Nitrosomonadales asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009090,GO:0009092,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0033554,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_3527 Bacteria 1MUHG@1224,2KKMI@206350,2VH2N@28216,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate HFDCGJPN_00533 582744.Msip34_1549 1e-177 630.9 Nitrosomonadales fimV ko:K07288,ko:K08086 ko00000 Bacteria 1MXV7@1224,2KMD2@206350,2VHX1@28216,COG3170@1,COG3170@2 NA|NA|NA NU pilus assembly protein FimV HFDCGJPN_00534 666681.M301_1175 3.1e-22 112.1 Nitrosomonadales ko:K02008,ko:K16785 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1N7EI@1224,2KP0B@206350,2VWJT@28216,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein HFDCGJPN_00535 265072.Mfla_1700 1.7e-102 379.0 Nitrosomonadales truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1MUYI@1224,2KKRM@206350,2VI0R@28216,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs HFDCGJPN_00536 1132855.KB913035_gene1713 7e-70 270.4 Nitrosomonadales trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1RA87@1224,2KMP3@206350,2VPZV@28216,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family HFDCGJPN_00537 582744.Msip34_2806 6.1e-237 826.6 Nitrosomonadales priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUUZ@1224,2KKNP@206350,2VINT@28216,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA HFDCGJPN_00539 582744.Msip34_2751 7.8e-303 1046.6 Nitrosomonadales Bacteria 1MUME@1224,2KMEF@206350,2VIKY@28216,COG2911@1,COG2911@2,COG2982@1,COG2982@2 NA|NA|NA M Domain of Unknown Function (DUF748) HFDCGJPN_00540 243365.CV_3465 4.7e-76 290.4 Neisseriales guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 1MU2A@1224,2KPJ8@206351,2VHNG@28216,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP HFDCGJPN_00541 1101195.Meth11DRAFT_0913 3.9e-173 614.4 Betaproteobacteria Bacteria 1PUZK@1224,2VKEF@28216,COG1055@1,COG1055@2 NA|NA|NA P Involved in arsenical resistance. Thought to form the channel of an arsenite pump HFDCGJPN_00542 582744.Msip34_1225 7.3e-62 243.4 Nitrosomonadales greB Bacteria 1RHU5@1224,2KMUI@206350,2W3NT@28216,COG0782@1,COG0782@2 NA|NA|NA K PFAM transcription elongation factor GreA GreB HFDCGJPN_00543 582744.Msip34_1224 5e-89 334.0 Nitrosomonadales ydgI ko:K15976 ko00000,ko01000 Bacteria 1RBZQ@1224,2KP6W@206350,2VQTZ@28216,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family HFDCGJPN_00544 582744.Msip34_1223 9.8e-294 1015.4 Nitrosomonadales ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1MU37@1224,2KMA8@206350,2VHGH@28216,COG0488@1,COG0488@2 NA|NA|NA S PFAM ABC transporter HFDCGJPN_00545 666681.M301_1920 2e-112 412.1 Nitrosomonadales Bacteria 1QG36@1224,2KN1Y@206350,2VK7Z@28216,COG0731@1,COG0731@2 NA|NA|NA C Radical SAM HFDCGJPN_00546 666681.M301_1919 5.1e-146 524.2 Nitrosomonadales Bacteria 1MU6I@1224,2KM0M@206350,2VIPS@28216,COG0654@1,COG0654@2 NA|NA|NA CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family HFDCGJPN_00548 582744.Msip34_1196 1.1e-182 646.4 Nitrosomonadales mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K18691 ko00000,ko01000,ko01011 iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 Bacteria 1MWDS@1224,2KKCY@206350,2VKSN@28216,COG4623@1,COG4623@2 NA|NA|NA M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella HFDCGJPN_00549 1101195.Meth11DRAFT_1611 2.4e-210 738.0 Nitrosomonadales serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1MUJF@1224,2KKNN@206350,2VHJJ@28216,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) HFDCGJPN_00550 1502770.JQMG01000001_gene2301 7.6e-128 463.4 Nitrosomonadales rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 ko:K07478 ko00000 Bacteria 1MUVS@1224,2KM8R@206350,2VHN9@28216,COG2256@1,COG2256@2 NA|NA|NA L PFAM AAA ATPase central domain protein HFDCGJPN_00551 1387312.BAUS01000004_gene1559 1.7e-28 131.3 Nitrosomonadales Bacteria 1N796@1224,2E8PT@1,2KN4R@206350,2VVUA@28216,3330W@2 NA|NA|NA HFDCGJPN_00552 1101195.Meth11DRAFT_0063 1.7e-97 362.1 Nitrosomonadales rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Bacteria 1MUK5@1224,2KKVM@206350,2VQ1Z@28216,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions HFDCGJPN_00553 583345.Mmol_0174 2.5e-116 424.9 Nitrosomonadales rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 1MVFZ@1224,2KKE3@206350,2VIGI@28216,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates HFDCGJPN_00554 1101195.Meth11DRAFT_0065 6.3e-99 367.5 Nitrosomonadales pphA 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1MVE7@1224,2KM5H@206350,2VIAV@28216,COG0631@1,COG0631@2 NA|NA|NA T SMART protein phosphatase 2C domain protein HFDCGJPN_00555 583345.Mmol_0176 8.4e-120 436.8 Nitrosomonadales Bacteria 1PJRR@1224,2KM3Q@206350,2VHMW@28216,COG0515@1,COG0515@2 NA|NA|NA KLT SMART serine threonine protein kinase HFDCGJPN_00556 582744.Msip34_0050 4e-108 397.9 Nitrosomonadales yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 Bacteria 1MWRA@1224,2KKC1@206350,2VIFC@28216,COG1561@1,COG1561@2 NA|NA|NA S Domain of unknown function (DUF1732) HFDCGJPN_00557 582744.Msip34_0051 1.4e-78 299.3 Nitrosomonadales gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 1MW92@1224,2KKGP@206350,2VPCK@28216,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP HFDCGJPN_00558 265072.Mfla_0049 4.5e-29 133.3 Nitrosomonadales rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1N6TX@1224,2KN43@206350,2VVUH@28216,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits HFDCGJPN_00559 582744.Msip34_0053 0.0 1300.8 Nitrosomonadales spoT GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475 Bacteria 1MU44@1224,2KKTM@206350,2VIA1@28216,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance HFDCGJPN_00560 697282.Mettu_3429 3.6e-82 311.2 Methylococcales ko:K07006 ko00000 Bacteria 1NBWC@1224,1S297@1236,1XEVD@135618,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase HFDCGJPN_00561 583345.Mmol_0186 2.3e-52 211.5 Nitrosomonadales yjgF 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 1MZ3J@1224,2KMVS@206350,2VRQ3@28216,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP HFDCGJPN_00564 582744.Msip34_1695 4.9e-188 664.1 Nitrosomonadales ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 Bacteria 1MUA8@1224,2KM23@206350,2VI5V@28216,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family HFDCGJPN_00565 582744.Msip34_1693 2e-226 791.6 Nitrosomonadales gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iEC042_1314.EC042_2616,iIT341.HP0476 Bacteria 1MUCR@1224,2KKGW@206350,2VH5S@28216,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) HFDCGJPN_00566 582744.Msip34_1692 6.4e-32 142.9 Nitrosomonadales hfq GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 Bacteria 1MZM1@1224,2KN6R@206350,2VTXK@28216,COG1923@1,COG1923@2 NA|NA|NA J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs HFDCGJPN_00567 582744.Msip34_0571 2.6e-201 708.0 Nitrosomonadales proA GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iYO844.BSU13130 Bacteria 1MUGJ@1224,2KKRJ@206350,2VJ5M@28216,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate HFDCGJPN_00568 1165096.ARWF01000001_gene2174 2.5e-54 218.8 Nitrosomonadales nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4,3.6.1.55 ko:K00969,ko:K01488,ko:K03574 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000,ko03400 iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 Bacteria 1RD0J@1224,2KMWI@206350,2VSQ7@28216,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) HFDCGJPN_00569 265072.Mfla_2160 2.2e-54 218.8 Nitrosomonadales bioD GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDRK@1224,2KMNW@206350,2VR4C@28216,COG0132@1,COG0132@2 NA|NA|NA H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring HFDCGJPN_00570 265072.Mfla_0060 1.4e-56 225.3 Nitrosomonadales erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 1RHCW@1224,2KMS7@206350,2VR2M@28216,COG0316@1,COG0316@2 NA|NA|NA C Required for insertion of 4Fe-4S clusters HFDCGJPN_00571 1165096.ARWF01000001_gene1444 6.8e-42 176.8 Nitrosomonadales ccmA Bacteria 1MZN0@1224,2KN14@206350,2VTZQ@28216,COG1664@1,COG1664@2 NA|NA|NA M Polymer-forming cytoskeletal HFDCGJPN_00572 582744.Msip34_0061 1.2e-46 193.4 Nitrosomonadales Bacteria 1R9DP@1224,28IJP@1,2KNB3@206350,2W9NP@28216,2Z8KI@2 NA|NA|NA HFDCGJPN_00573 582744.Msip34_0060 6.8e-171 606.7 Nitrosomonadales argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1MVJ6@1224,2KKWJ@206350,2VJD7@28216,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde HFDCGJPN_00574 265072.Mfla_0056 4.5e-59 233.8 Nitrosomonadales rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RD4A@1224,2KMQG@206350,2VR5R@28216,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family HFDCGJPN_00575 582744.Msip34_0058 9.3e-77 292.7 Nitrosomonadales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RA11@1224,2KMN4@206350,2VQ07@28216,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly HFDCGJPN_00576 1236959.BAMT01000017_gene2350 1.2e-107 396.4 Nitrosomonadales ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 iZ_1308.Z5639 Bacteria 1MV4Q@1224,2KKRC@206350,2VHEU@28216,COG0382@1,COG0382@2 NA|NA|NA H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate HFDCGJPN_00577 1165096.ARWF01000001_gene1451 9.2e-58 229.9 Nitrosomonadales ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z5638 Bacteria 1N8BF@1224,2KN0H@206350,2VU5V@28216,COG3161@1,COG3161@2 NA|NA|NA H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway HFDCGJPN_00579 582744.Msip34_0055 4.4e-114 417.5 Nitrosomonadales recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWN2@1224,2KKN8@206350,2VHE8@28216,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) HFDCGJPN_00580 204773.HEAR0718 6.3e-72 277.7 Oxalobacteraceae Bacteria 1QV5U@1224,2WAER@28216,472QW@75682,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 HFDCGJPN_00581 748247.AZKH_0942 3e-108 399.1 Betaproteobacteria Bacteria 1R6ES@1224,2VNAA@28216,COG3307@1,COG3307@2 NA|NA|NA M Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology HFDCGJPN_00582 748247.AZKH_0944 4.8e-62 244.2 Betaproteobacteria 2.3.1.30,6.2.1.41 ko:K00640,ko:K18687 ko00270,ko00920,ko00984,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map00984,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586,R10769 RC00004,RC00014,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1RC2G@1224,2WENR@28216,COG1045@1,COG1045@2 NA|NA|NA E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology HFDCGJPN_00583 697282.Mettu_4229 2e-161 575.5 Methylococcales epsN ko:K16703 ko00000,ko01000,ko01003 GT4 Bacteria 1MVKK@1224,1RQ8J@1236,1XFN6@135618,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase, group 1 HFDCGJPN_00584 582744.Msip34_1823 1.7e-101 376.3 Nitrosomonadales epsO Bacteria 1PU38@1224,2KKGU@206350,2VKWD@28216,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 HFDCGJPN_00585 381666.H16_B0018 8.1e-34 151.4 Burkholderiaceae Bacteria 1K2X3@119060,1RICE@1224,2VV24@28216,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase HFDCGJPN_00586 697282.Mettu_4227 6.7e-107 394.0 Gammaproteobacteria Bacteria 1P3TJ@1224,1RZ5U@1236,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family HFDCGJPN_00587 697282.Mettu_4226 5.3e-128 464.2 Gammaproteobacteria Bacteria 1N7B9@1224,1SR8Z@1236,2DKW5@1,30J7Z@2 NA|NA|NA HFDCGJPN_00588 1005048.CFU_2727 6.7e-70 270.8 Oxalobacteraceae gumM 2.4.1.187,2.4.1.252 ko:K05946,ko:K13657,ko:K13660 ko05111,map05111 R09733 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 GT26,GT4 Bacteria 1N1HD@1224,2VS17@28216,478U9@75682,COG1922@1,COG1922@2 NA|NA|NA M Glycosyl transferase WecB/TagA/CpsF family HFDCGJPN_00589 582744.Msip34_1820 6.3e-145 520.4 Nitrosomonadales galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUHI@1224,2KKP7@206350,2VIN9@28216,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family HFDCGJPN_00590 666681.M301_2246 8.6e-130 469.9 Nitrosomonadales galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV5F@1224,2KM2M@206350,2VH00@28216,COG1210@1,COG1210@2 NA|NA|NA M PFAM Nucleotidyl transferase HFDCGJPN_00591 583345.Mmol_1798 1.9e-77 296.6 Nitrosomonadales Bacteria 1RE1P@1224,2KMMN@206350,2VR77@28216,COG5338@1,COG5338@2 NA|NA|NA S TIGRFAM exopolysaccharide biosynthesis operon protein EpsL HFDCGJPN_00592 371042.NG99_23425 1.4e-90 339.7 Erwinia metXA 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 1MVJV@1224,1RQ2N@1236,3X7JV@551,COG2021@1,COG2021@2 NA|NA|NA E Belongs to the AB hydrolase superfamily. MetX family HFDCGJPN_00593 666681.M301_2094 1e-92 347.4 Nitrosomonadales pleD Bacteria 1R7HC@1224,2KNFU@206350,2VH1X@28216,COG2199@1,COG3447@1,COG3447@2,COG3706@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_00597 666681.M301_2177 6.8e-47 193.7 Nitrosomonadales ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1RH2Y@1224,2KMZT@206350,2VSQF@28216,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family HFDCGJPN_00598 1236959.BAMT01000014_gene2919 1.2e-61 242.7 Nitrosomonadales pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 Bacteria 1MZJA@1224,2KN19@206350,2VSP2@28216,COG1267@1,COG1267@2 NA|NA|NA I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) HFDCGJPN_00599 666681.M301_2175 1.9e-106 392.5 Nitrosomonadales thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iSFV_1184.SFV_0382,iYO844.BSU05900 Bacteria 1MU9X@1224,2KKQ6@206350,2VI0Q@28216,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 HFDCGJPN_00600 582744.Msip34_2185 1.3e-89 335.9 Nitrosomonadales mog GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75,2.8.1.12 ko:K03635,ko:K03831 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395,R09726 RC00002,RC02507 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1969,iECABU_c1320.ECABU_c00100,iECED1_1282.ECED1_0009,iECNA114_1301.ECNA114_4653,iECP_1309.ECP_0010,iECS88_1305.ECS88_0010,iECSF_1327.ECSF_0009,iECUMN_1333.ECUMN_0010,iEcSMS35_1347.EcSMS35_0008,iLF82_1304.LF82_1379,iNRG857_1313.NRG857_00050,iUMN146_1321.UM146_22820 Bacteria 1R9W2@1224,2KMHF@206350,2VH28@28216,COG0521@1,COG0521@2 NA|NA|NA H TIGRFAM molybdenum cofactor synthesis domain HFDCGJPN_00601 582744.Msip34_2184 5.4e-34 151.4 Nitrosomonadales Bacteria 1NM18@1224,2KN53@206350,2W7YW@28216,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. HFDCGJPN_00602 582744.Msip34_2183 9.5e-246 856.3 Nitrosomonadales gcr Bacteria 1MWEH@1224,2KKY4@206350,2VIZV@28216,COG4389@1,COG4389@2 NA|NA|NA L Site-specific recombinase HFDCGJPN_00603 1236959.BAMT01000014_gene2931 1.1e-64 253.1 Nitrosomonadales yjgA ko:K09889 ko00000,ko03009 Bacteria 1MZ4R@1224,2KMRU@206350,2VSGZ@28216,COG3028@1,COG3028@2 NA|NA|NA S Belongs to the UPF0307 family HFDCGJPN_00604 582744.Msip34_0064 5e-211 740.3 Nitrosomonadales gltA GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 iIT341.HP0026 Bacteria 1MUKX@1224,2KM12@206350,2VIJF@28216,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family HFDCGJPN_00605 582744.Msip34_0065 3.7e-119 434.9 Nitrosomonadales anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 ko:K07106,ko:K09001 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 Bacteria 1MV4E@1224,2KMHH@206350,2VHCE@28216,COG2377@1,COG2377@2 NA|NA|NA O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling HFDCGJPN_00606 582744.Msip34_0066 2.9e-177 628.2 Nitrosomonadales yebA Bacteria 1MVTF@1224,2KM8B@206350,2VHBS@28216,COG0739@1,COG0739@2 NA|NA|NA M PFAM peptidase HFDCGJPN_00607 582744.Msip34_0067 2.2e-189 668.3 Nitrosomonadales tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN746.PP_0436,iLJ478.TM0478 Bacteria 1MVUQ@1224,2KKIA@206350,2VHF7@28216,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) HFDCGJPN_00609 1236959.BAMT01000001_gene1439 6.4e-145 520.4 Nitrosomonadales hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MW7I@1224,2KKY8@206350,2VIPQ@28216,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily HFDCGJPN_00610 1236959.BAMT01000001_gene1440 1.7e-157 562.0 Nitrosomonadales pqqB GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 3.1.4.55 ko:K06136,ko:K06167 ko00440,map00440 R10205 RC00296 ko00000,ko00001,ko01000 Bacteria 1MWI5@1224,2KM3R@206350,2VJUF@28216,COG1235@1,COG1235@2 NA|NA|NA S May be involved in the transport of PQQ or its precursor to the periplasm HFDCGJPN_00611 1387312.BAUS01000012_gene2116 1.5e-135 488.8 Nitrosomonadales pqqC 1.3.3.11 ko:K06137 ko00000,ko01000 Bacteria 1MW7G@1224,2KMD0@206350,2VI0X@28216,COG5424@1,COG5424@2 NA|NA|NA H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ HFDCGJPN_00612 582744.Msip34_1526 1.8e-33 148.3 Nitrosomonadales pqqD ko:K06138 ko00000 Bacteria 1N7JR@1224,2E4CK@1,2KN6H@206350,2VVSC@28216,32Z81@2 NA|NA|NA S PFAM coenzyme PQQ synthesis HFDCGJPN_00613 582744.Msip34_1525 5.3e-220 770.0 Nitrosomonadales pqqE ko:K06139 ko00000 Bacteria 1MUQP@1224,2KMCY@206350,2VIK6@28216,COG0535@1,COG0535@2 NA|NA|NA S TIGRFAM coenzyme PQQ biosynthesis protein E HFDCGJPN_00614 626418.bglu_1g16460 4.4e-88 331.3 Burkholderiaceae Bacteria 1K6ED@119060,1RIYU@1224,2VWI0@28216,COG2520@1,COG2520@2 NA|NA|NA J FkbM family HFDCGJPN_00615 1502770.JQMG01000001_gene2122 2.1e-152 545.4 Nitrosomonadales bcr ko:K07552 ko00000,ko02000 2.A.1.2 Bacteria 1MW19@1224,2KM4Z@206350,2VHTW@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily HFDCGJPN_00616 748247.AZKH_4524 1.3e-16 94.4 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KZTM@206389,2VNQ5@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00617 1387312.BAUS01000002_gene733 6.2e-54 216.5 Nitrosomonadales fdxA ko:K05524 ko00000 Bacteria 1RH5I@1224,2KN07@206350,2VSJ0@28216,COG1146@1,COG1146@2 NA|NA|NA C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions HFDCGJPN_00618 582744.Msip34_1521 1.9e-190 671.8 Nitrosomonadales cysN GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUD9@1224,2KKI9@206350,2VHYV@28216,COG2895@1,COG2895@2 NA|NA|NA P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily HFDCGJPN_00619 582744.Msip34_0860 3.9e-21 107.5 Nitrosomonadales ftsB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 ko:K05589 ko00000,ko03036 Bacteria 1N7AA@1224,2KN3C@206350,2VVQJ@28216,COG2919@1,COG2919@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic HFDCGJPN_00620 582744.Msip34_0859 1.3e-224 785.4 Nitrosomonadales eno GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1MU1N@1224,2KM0W@206350,2VH7Y@28216,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis HFDCGJPN_00621 1122236.KB905141_gene1109 3e-148 531.2 Nitrosomonadales kdsA 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MV91@1224,2KM8V@206350,2VIQF@28216,COG2877@1,COG2877@2 NA|NA|NA M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HFDCGJPN_00622 582744.Msip34_0857 5.8e-289 999.6 Nitrosomonadales pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 1MUIT@1224,2KMB4@206350,2VHVA@28216,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates HFDCGJPN_00623 1132855.KB913035_gene463 1.2e-171 609.4 Nitrosomonadales salY ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1PBKH@1224,2KKHY@206350,2W3RM@28216,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain HFDCGJPN_00624 583345.Mmol_2102 1.4e-98 365.9 Nitrosomonadales macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MU45@1224,2KM1C@206350,2VKEW@28216,COG1136@1,COG1136@2 NA|NA|NA V PFAM ABC transporter HFDCGJPN_00625 582744.Msip34_1221 2.5e-132 478.8 Nitrosomonadales macA_1 ko:K02005,ko:K13888 M00709 ko00000,ko00002,ko02000 8.A.1 Bacteria 1MU8D@1224,2KMH1@206350,2VH9K@28216,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like HFDCGJPN_00626 582744.Msip34_1222 6.1e-149 534.3 Nitrosomonadales Bacteria 1MWX5@1224,2KKUR@206350,2VHU4@28216,COG1538@1,COG1538@2 NA|NA|NA MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) HFDCGJPN_00627 582744.Msip34_1052 3e-71 275.0 Nitrosomonadales ko:K09939 ko00000 Bacteria 1RF14@1224,2KNJ4@206350,2VSCE@28216,COG3295@1,COG3295@2 NA|NA|NA S Putative PepSY_TM-like HFDCGJPN_00628 1116472.MGMO_103c00260 2.8e-64 251.9 Methylococcales piuC ko:K07336 ko00000,ko01000 Bacteria 1MUI7@1224,1RQ0M@1236,1XGDN@135618,COG3128@1,COG3128@2 NA|NA|NA C Prolyl 4-hydroxylase alpha subunit homologues. HFDCGJPN_00629 1116472.MGMO_103c00250 1.9e-210 739.2 Methylococcales fiu GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0009279,GO:0015688,GO:0015833,GO:0015891,GO:0015893,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044462,GO:0044464,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:1901678 ko:K16090 ko00000,ko02000 1.B.14.1.11 iLF82_1304.LF82_0668,iNRG857_1313.NRG857_03600,iYL1228.KPN_01250 Bacteria 1MV0X@1224,1RN3C@1236,1XE82@135618,COG4774@1,COG4774@2 NA|NA|NA P PFAM TonB-dependent Receptor HFDCGJPN_00630 583345.Mmol_2106 5.8e-52 210.3 Nitrosomonadales exbD1 ko:K03559,ko:K03560 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1MZ6M@1224,2KN0J@206350,2VSVW@28216,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR HFDCGJPN_00631 582744.Msip34_1760 2.9e-62 245.4 Nitrosomonadales exbB ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1NMPB@1224,2KMAX@206350,2VJ4U@28216,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel HFDCGJPN_00632 666681.M301_2530 3.5e-26 125.6 Nitrosomonadales tonB1 ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1MZPX@1224,2KMXT@206350,2VM32@28216,COG0810@1,COG0810@2 NA|NA|NA M Gram-negative bacterial TonB protein C-terminal HFDCGJPN_00633 265072.Mfla_0875 1.2e-17 95.5 Nitrosomonadales Bacteria 1PJKI@1224,2BUMP@1,2KNC4@206350,2W81Q@28216,32PYD@2 NA|NA|NA HFDCGJPN_00635 472759.Nhal_1793 5.8e-126 457.6 Chromatiales Bacteria 1MW2S@1224,1RZFD@1236,1X1JZ@135613,COG3182@1,COG3182@2 NA|NA|NA S PepSY-associated TM region HFDCGJPN_00636 582744.Msip34_0436 3.6e-302 1043.9 Nitrosomonadales fhuE ko:K16088 ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 Bacteria 1MW5E@1224,2KM5W@206350,2VHUH@28216,COG4773@1,COG4773@2 NA|NA|NA P TonB dependent receptor HFDCGJPN_00637 1122236.KB905151_gene2242 1.2e-37 162.2 Nitrosomonadales htpG GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701 ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Bacteria 1MUUE@1224,2KM57@206350,2VHHJ@28216,COG0326@1,COG0326@2 NA|NA|NA O Molecular chaperone. Has ATPase activity HFDCGJPN_00638 1097668.BYI23_A015210 1.1e-23 116.7 Burkholderiaceae Bacteria 1K6ER@119060,1R554@1224,2VKBV@28216,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase, family 2 HFDCGJPN_00639 582744.Msip34_1790 1.2e-65 256.5 Nitrosomonadales ko:K09929 ko00000 Bacteria 1R8C9@1224,2KMRC@206350,2VPVN@28216,COG3219@1,COG3219@2 NA|NA|NA S Putative DNA-binding domain HFDCGJPN_00640 582744.Msip34_1791 3.1e-124 451.4 Nitrosomonadales ko:K09930 ko00000 Bacteria 1MURE@1224,2KMHR@206350,2VKP0@28216,COG3220@1,COG3220@2 NA|NA|NA S Protein of unknown function (DUF692) HFDCGJPN_00641 582744.Msip34_1792 1.3e-17 95.9 Nitrosomonadales 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1PW8F@1224,2KN9B@206350,2WBTI@28216,COG3767@1,COG3767@2 NA|NA|NA HFDCGJPN_00642 582744.Msip34_1793 1.3e-19 102.1 Nitrosomonadales Bacteria 1NH4R@1224,2KNB0@206350,2W81G@28216,COG5660@1,COG5660@2 NA|NA|NA S Putative zinc-finger HFDCGJPN_00643 582744.Msip34_1794 1.8e-77 295.4 Nitrosomonadales sigX ko:K03088 ko00000,ko03021 Bacteria 1RHKM@1224,2KM2U@206350,2VRMP@28216,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase sigma factor, sigma-70 family HFDCGJPN_00644 582744.Msip34_1795 2.5e-58 231.5 Nitrosomonadales Bacteria 1RH66@1224,2AFCJ@1,2KMYR@206350,2VSTN@28216,315C6@2 NA|NA|NA S Domain of unknown function (DUF1841) HFDCGJPN_00645 666681.M301_2380 6e-101 374.4 Nitrosomonadales GO:0008150,GO:0040007 Bacteria 1RBRR@1224,2KMA1@206350,2VQ7K@28216,COG4398@1,COG4398@2 NA|NA|NA S FIST_C HFDCGJPN_00646 265072.Mfla_0851 1.9e-91 342.0 Nitrosomonadales nth GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUYQ@1224,2KM03@206350,2VIRB@28216,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate HFDCGJPN_00647 583345.Mmol_1959 1.8e-87 328.9 Nitrosomonadales rnfE ko:K03613 ko00000 Bacteria 1MW6N@1224,2KNJX@206350,2VNWT@28216,COG4660@1,COG4660@2 NA|NA|NA C Part of a membrane complex involved in electron transport HFDCGJPN_00648 666681.M301_2377 7.2e-62 243.8 Nitrosomonadales rnfG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03612 ko00000 Bacteria 1RDEP@1224,2KNPE@206350,2VS39@28216,COG4659@1,COG4659@2 NA|NA|NA U Part of a membrane complex involved in electron transport HFDCGJPN_00649 666681.M301_2376 6.6e-142 510.4 Nitrosomonadales rnfD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 1.6.5.8 ko:K00347,ko:K03614 ko00000,ko01000 Bacteria 1MVY6@1224,2KNQE@206350,2VJZJ@28216,COG4658@1,COG4658@2 NA|NA|NA C Part of a membrane complex involved in electron transport HFDCGJPN_00650 666681.M301_2375 6.7e-184 650.6 Nitrosomonadales rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 ko:K03466,ko:K03615,ko:K03616,ko:K03821 ko00650,map00650 R04254 RC00004 ko00000,ko00001,ko01000,ko03036 3.A.12 Bacteria 1PJVF@1224,2KNEK@206350,2VM4P@28216,COG3064@1,COG3064@2,COG4656@1,COG4656@2 NA|NA|NA CM Part of a membrane complex involved in electron transport HFDCGJPN_00651 1502770.JQMG01000001_gene405 8.8e-80 303.1 Nitrosomonadales rnfB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 1.12.98.1 ko:K00441,ko:K03616 ko00680,ko01100,ko01120,map00680,map01100,map01120 R03025 RC02628 ko00000,ko00001,ko01000 Bacteria 1MUWU@1224,2KMT4@206350,2VN5I@28216,COG2878@1,COG2878@2 NA|NA|NA C Part of a membrane complex involved in electron transport HFDCGJPN_00652 1485544.JQKP01000001_gene1057 4.4e-74 284.3 Nitrosomonadales rnfA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 ko:K03617 ko00000 Bacteria 1MU8X@1224,2VH0C@28216,44VIU@713636,COG4657@1,COG4657@2 NA|NA|NA C Part of a membrane complex involved in electron transport HFDCGJPN_00653 582744.Msip34_1799 1.2e-131 476.1 Nitrosomonadales dapA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2492,iYL1228.KPN_02812 Bacteria 1MUCM@1224,2KM15@206350,2VIQ4@28216,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) HFDCGJPN_00654 582744.Msip34_1800 1e-144 520.0 Nitrosomonadales bamC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045229,GO:0061024,GO:0071709,GO:0071840,GO:0071944,GO:0098552,GO:0098796,GO:1990063 ko:K07287 ko00000,ko02000 1.B.33.1 Bacteria 1N670@1224,2KM3U@206350,2VHS5@28216,COG3317@1,COG3317@2 NA|NA|NA M NlpB/DapX lipoprotein HFDCGJPN_00655 1122236.KB905141_gene1718 1.2e-98 366.3 Nitrosomonadales yycJ Bacteria 1R5N4@1224,2KKWM@206350,2VKSE@28216,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain HFDCGJPN_00657 1165096.ARWF01000001_gene2096 1.3e-39 169.5 Nitrosomonadales Bacteria 1N8MS@1224,2E3EJ@1,2KN6C@206350,2VW4J@28216,32YDJ@2 NA|NA|NA HFDCGJPN_00658 1236959.BAMT01000001_gene1110 4.4e-139 501.1 Nitrosomonadales ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 ko00000,ko01000,ko03009 Bacteria 1MW30@1224,2KKDU@206350,2VH3D@28216,COG2850@1,COG2850@2 NA|NA|NA S SMART transcription factor jumonji jmjC domain protein HFDCGJPN_00659 582744.Msip34_1806 1.1e-64 252.7 Nitrosomonadales 1.11.1.15,2.7.13.3 ko:K03564,ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1RD4R@1224,2KNT0@206350,2VRCR@28216,COG1225@1,COG1225@2 NA|NA|NA O Redoxin HFDCGJPN_00660 582744.Msip34_1067 2.1e-139 501.9 Nitrosomonadales ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1MV5H@1224,2KKWC@206350,2VHAG@28216,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity HFDCGJPN_00661 1165096.ARWF01000001_gene16 1.1e-70 273.9 Betaproteobacteria Bacteria 1RD0X@1224,2VS0D@28216,COG2114@1,COG2114@2 NA|NA|NA T Adenylate and Guanylate cyclase catalytic domain HFDCGJPN_00662 582744.Msip34_1066 7.8e-99 367.5 Nitrosomonadales Bacteria 1RJ6K@1224,2KMHP@206350,2VTPG@28216,COG2199@1,COG2199@2,COG5278@1,COG5278@2 NA|NA|NA T TIGRFAM diguanylate cyclase HFDCGJPN_00663 228410.NE0286 1.5e-37 162.5 Nitrosomonadales Bacteria 1N27R@1224,2C3ZQ@1,2WA3K@28216,32SCF@2,373PU@32003 NA|NA|NA S MEKHLA domain HFDCGJPN_00664 582744.Msip34_1063 0.0 1204.5 Nitrosomonadales rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU0G@1224,2KM7U@206350,2VJFM@28216,COG0210@1,COG0210@2 NA|NA|NA L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction HFDCGJPN_00665 583345.Mmol_1237 3.6e-282 977.2 Nitrosomonadales uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1MU37@1224,2KKC3@206350,2VH4J@28216,COG0488@1,COG0488@2 NA|NA|NA S PFAM ABC transporter HFDCGJPN_00666 583345.Mmol_1091 1.3e-104 386.3 Nitrosomonadales Bacteria 1MWFY@1224,28JGK@1,2KKEE@206350,2VQFN@28216,2Z9AA@2 NA|NA|NA S Protein of unknown function (DUF3034) HFDCGJPN_00667 582744.Msip34_2306 2.6e-39 168.3 Nitrosomonadales glbN ko:K06886 ko00000 Bacteria 1N005@1224,2KN4Y@206350,2VUPJ@28216,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin HFDCGJPN_00668 582744.Msip34_2307 7.7e-61 240.4 Nitrosomonadales Bacteria 1RHQU@1224,2KMUS@206350,2VSJJ@28216,COG3794@1,COG3794@2 NA|NA|NA C PFAM blue (type 1) copper domain protein HFDCGJPN_00669 666681.M301_0804 1.5e-237 829.3 Nitrosomonadales yclK GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023051,GO:0023052,GO:0023057,GO:0035556,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046983,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070297,GO:0070298,GO:0071704,GO:0140096,GO:1901564,GO:1902531,GO:1902532 2.7.13.3 ko:K02484,ko:K07653,ko:K07654,ko:K11617 ko02020,map02020 M00460,M00461,M00481,M00754 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MU2C@1224,2KKX2@206350,2VHPI@28216,COG2972@1,COG2972@2,COG5001@1,COG5001@2 NA|NA|NA T histidine kinase HAMP region domain protein HFDCGJPN_00670 56107.Cylst_0426 7.3e-34 152.9 Nostocales Bacteria 1GQ7S@1117,1HRXM@1161,COG0823@1,COG0823@2,COG5276@1,COG5276@2 NA|NA|NA Q LVIVD repeat HFDCGJPN_00671 582744.Msip34_0862 7.7e-58 233.8 Nitrosomonadales 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1PGC5@1224,2KNZF@206350,2W9Y6@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00673 1165096.ARWF01000001_gene6 6.4e-56 223.8 Nitrosomonadales bcp 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 1RH4P@1224,2KMST@206350,2VT1P@28216,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_00674 748247.AZKH_4524 2.7e-26 127.1 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KZTM@206389,2VNQ5@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_00676 582744.Msip34_1015 1.5e-200 706.1 Nitrosomonadales aggA ko:K12543 M00330 ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 Bacteria 1MYX2@1224,2KM5M@206350,2VKDN@28216,COG1538@1,COG1538@2,COG4319@1,COG4319@2 NA|NA|NA MU TIGRFAM type I secretion outer membrane protein, TolC family HFDCGJPN_00677 582744.Msip34_1014 8.1e-75 287.0 Nitrosomonadales Bacteria 1RDQS@1224,2KMPG@206350,2VR6A@28216,COG3672@1,COG3672@2 NA|NA|NA S Bacterial transglutaminase-like cysteine proteinase BTLCP HFDCGJPN_00678 582744.Msip34_1013 2.9e-175 622.1 Nitrosomonadales lapD Bacteria 1MUQV@1224,2KKV1@206350,2VJ24@28216,COG2199@1,COG2199@2,COG2200@1,COG2200@2 NA|NA|NA T histidine kinase HAMP region domain protein HFDCGJPN_00679 666681.M301_0635 1.5e-21 109.0 Nitrosomonadales Bacteria 1N79W@1224,2E4XG@1,2KN90@206350,2VX4E@28216,32ZRD@2 NA|NA|NA S tryptophan synthase subunit beta HFDCGJPN_00680 1122599.AUGR01000032_gene35 7.8e-151 542.3 Oceanospirillales Bacteria 1MU7T@1224,1RMZW@1236,1XMTQ@135619,COG2304@1,COG2304@2,COG2931@1,COG2931@2 NA|NA|NA Q von willebrand factor, type A HFDCGJPN_00681 582744.Msip34_2347 9.8e-129 466.5 Nitrosomonadales ko:K02030,ko:K16254 ko00680,ko01120,map00680,map01120 M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1MWWZ@1224,2KMAA@206350,2VNAR@28216,COG0834@1,COG0834@2 NA|NA|NA ET SMART extracellular solute-binding protein, family 3 HFDCGJPN_00682 1101195.Meth11DRAFT_2329 9.3e-60 236.5 Nitrosomonadales Bacteria 1QBNV@1224,2KMPU@206350,2W7YT@28216,COG2010@1,COG2010@2 NA|NA|NA C Pfam cytochrome c HFDCGJPN_00683 582744.Msip34_2345 6.6e-61 240.4 Nitrosomonadales ko:K16255 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1RJZG@1224,2KMK6@206350,2W3VV@28216,COG2010@1,COG2010@2 NA|NA|NA C PFAM cytochrome c HFDCGJPN_00684 582744.Msip34_2344 1.1e-218 765.8 Nitrosomonadales ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1MX96@1224,2KMDP@206350,2VJR6@28216,COG1252@1,COG1252@2 NA|NA|NA C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase HFDCGJPN_00685 582744.Msip34_2343 7.2e-177 626.7 Nitrosomonadales lplT ko:K08227 ko00000,ko02000 2.A.1.42 Bacteria 1QTWR@1224,2KPAT@206350,2VIC5@28216,COG0477@1,COG2814@2 NA|NA|NA EGP PFAM Major Facilitator Superfamily HFDCGJPN_00686 265072.Mfla_2309 3.9e-246 857.1 Nitrosomonadales phoH ko:K07175 ko00000 Bacteria 1MUX1@1224,2KM2C@206350,2VH4P@28216,COG1875@1,COG1875@2 NA|NA|NA T PFAM PhoH family protein HFDCGJPN_00687 1165096.ARWF01000001_gene1989 4.9e-65 253.8 Nitrosomonadales bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 1RD4R@1224,2KMRJ@206350,2VR4P@28216,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_00688 582744.Msip34_2340 2.9e-191 674.9 Nitrosomonadales Bacteria 1RC7X@1224,2KKTN@206350,2VN1K@28216,COG4191@1,COG4191@2 NA|NA|NA T histidine kinase HAMP region domain protein HFDCGJPN_00689 1165096.ARWF01000001_gene1991 3.4e-17 95.5 Nitrosomonadales ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1PE9F@1224,2KNAJ@206350,2VXP2@28216,COG0810@1,COG0810@2 NA|NA|NA M TIGRFAM TonB family protein HFDCGJPN_00690 582744.Msip34_2337 1.7e-109 402.5 Nitrosomonadales Bacteria 1MX4H@1224,2KM5B@206350,2VM8B@28216,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily HFDCGJPN_00691 583345.Mmol_0017 3.8e-73 281.2 Nitrosomonadales ko:K12262 ko00000 Bacteria 1MZ7X@1224,2KKS2@206350,2VS28@28216,COG3038@1,COG3038@2 NA|NA|NA C PFAM cytochrome B561 HFDCGJPN_00692 582744.Msip34_2335 1.3e-105 389.4 Nitrosomonadales MA20_34470 ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 Bacteria 1PB0I@1224,2KM3W@206350,2VNJJ@28216,COG5501@1,COG5501@2 NA|NA|NA S Sulphur oxidation protein SoxZ HFDCGJPN_00693 1218076.BAYB01000002_gene451 8.6e-42 176.4 Burkholderiaceae MA20_25940 ko:K08234 ko00000 Bacteria 1KHF4@119060,1N7R0@1224,2VV7K@28216,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HFDCGJPN_00694 583345.Mmol_2038 2.5e-124 451.8 Nitrosomonadales moeA1 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 1MVD5@1224,2KKRZ@206350,2VH78@28216,COG0303@1,COG0303@2 NA|NA|NA H PFAM MoeA domain protein domain I and II HFDCGJPN_00696 582744.Msip34_1025 8.7e-130 470.3 Nitrosomonadales pilC ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1N8FA@1224,2KMAF@206350,2VJ0W@28216,COG1459@1,COG1459@2 NA|NA|NA NU PFAM type II secretion system HFDCGJPN_00697 582744.Msip34_1024 5.3e-57 227.3 Nitrosomonadales gspG2 ko:K02246,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1RDX2@1224,2KMQV@206350,2VR66@28216,COG2165@1,COG2165@2 NA|NA|NA U type II secretion system protein G HFDCGJPN_00698 582744.Msip34_2437 0.0 1108.6 Nitrosomonadales Bacteria 1MU2C@1224,2KNJ1@206350,2VH3V@28216,COG5001@1,COG5001@2,COG5002@1,COG5002@2 NA|NA|NA T PFAM EAL domain protein HFDCGJPN_00699 278957.ABEA03000099_gene872 1.4e-42 180.3 Opitutae 5.2.1.8 ko:K01802,ko:K03769 ko00000,ko01000,ko03110 Bacteria 3K8ZT@414999,46XKD@74201,COG0760@1,COG0760@2 NA|NA|NA O PPIC-type PPIASE domain HFDCGJPN_00700 582744.Msip34_1864 1.6e-163 582.4 Nitrosomonadales ko:K00786 ko00000,ko01000 Bacteria 1MUB7@1224,2KMIK@206350,2VN6W@28216,COG0438@1,COG0438@2 NA|NA|NA M PFAM glycosyl transferase group 1 HFDCGJPN_00701 265072.Mfla_0788 1.1e-46 192.6 Nitrosomonadales dgkA 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1MZ3Q@1224,2KMXB@206350,2VU5Y@28216,COG0818@1,COG0818@2 NA|NA|NA M Recycling of diacylglycerol produced during the turnover of membrane phospholipid HFDCGJPN_00702 582744.Msip34_1867 2.4e-105 388.7 Nitrosomonadales Bacteria 1RG4V@1224,2DJVG@1,2KMGW@206350,2VS8I@28216,307GH@2 NA|NA|NA S Zinc dependent phospholipase C HFDCGJPN_00703 357804.Ping_0587 4.9e-38 163.7 Psychromonadaceae ynfA GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K09771 ko00000,ko02000 2.A.7.26 Bacteria 1MZI8@1224,1SA4U@1236,2QJ7B@267894,COG1742@1,COG1742@2 NA|NA|NA S Uncharacterised BCR, YnfA/UPF0060 family HFDCGJPN_00704 265072.Mfla_0769 4.2e-104 384.4 Nitrosomonadales hldE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 ko:K03272,ko:K21344 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MV3Z@1224,2KKBG@206350,2VHNS@28216,COG0615@1,COG0615@2,COG2870@1,COG2870@2 NA|NA|NA H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose HFDCGJPN_00705 1236959.BAMT01000001_gene1024 8.1e-140 503.4 Nitrosomonadales rfaF GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K02843 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 iECH74115_1262.ECH74115_4993,iECSP_1301.ECSP_4617,iECs_1301.ECs4498,iG2583_1286.G2583_4359,iZ_1308.Z5047 Bacteria 1MXA2@1224,2KM3T@206350,2VHHX@28216,COG0859@1,COG0859@2 NA|NA|NA M TIGRFAM lipopolysaccharide heptosyltransferase II HFDCGJPN_00706 1454004.AW11_01921 4e-52 211.5 Betaproteobacteria cat 2.3.1.28 ko:K00638,ko:K18234 br01600,ko00000,ko01000,ko01504 Bacteria 1MUCJ@1224,2VVR8@28216,COG0110@1,COG0110@2 NA|NA|NA M Bacterial transferase hexapeptide (six repeats) HFDCGJPN_00707 1101195.Meth11DRAFT_1923 3.1e-15 87.8 Bacteria Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 HFDCGJPN_00708 1165096.ARWF01000001_gene1239 6.3e-221 773.1 Nitrosomonadales tuf ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 1MVC0@1224,2KKR0@206350,2VH5D@28216,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis HFDCGJPN_00713 1132855.KB913035_gene2509 5.9e-44 183.7 Nitrosomonadales sspB GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 ko:K03600,ko:K09985 ko00000,ko03021 Bacteria 1MZ2Q@1224,2KMYV@206350,2VSGG@28216,COG2969@1,COG2969@2 NA|NA|NA S PFAM Stringent starvation protein B HFDCGJPN_00714 582744.Msip34_0285 6.2e-100 370.2 Nitrosomonadales sspA GO:0001000,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0008150,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0042594,GO:0043175,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K03599 ko00000,ko02000,ko03021 1.A.12.3.1 Bacteria 1MXJD@1224,2KKGC@206350,2VIAW@28216,COG0625@1,COG0625@2 NA|NA|NA O Belongs to the GST superfamily HFDCGJPN_00715 582744.Msip34_0284 9.4e-95 353.2 Nitrosomonadales petC ko:K00410,ko:K00412,ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 ko00000,ko00001,ko00002,ko03029 iIT341.HP1538 Bacteria 1QFU2@1224,2KMIM@206350,2VIR6@28216,COG2857@1,COG2857@2 NA|NA|NA C PFAM Cytochrome C1 HFDCGJPN_00716 582744.Msip34_0283 7.1e-226 789.6 Nitrosomonadales petB ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 ko00000,ko00001,ko00002,ko00194,ko03029 Bacteria 1MV97@1224,2KKSW@206350,2VHP5@28216,COG1290@1,COG1290@2 NA|NA|NA C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis HFDCGJPN_00717 582744.Msip34_0282 4.7e-92 344.0 Nitrosomonadales petA 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 ko00000,ko00001,ko00002,ko01000 Bacteria 1RAA2@1224,2KM0P@206350,2VK46@28216,COG0723@1,COG0723@2 NA|NA|NA C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis HFDCGJPN_00718 666681.M301_0316 1.1e-93 349.7 Nitrosomonadales ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVUN@1224,2KKRS@206350,2VIX1@28216,COG0327@1,COG0327@2 NA|NA|NA S NIF3 (NGG1p interacting factor 3) HFDCGJPN_00719 582744.Msip34_0280 9e-172 609.8 Nitrosomonadales degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0051716,GO:0051788,GO:0061077,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2KKS5@206350,2VJ9G@28216,COG0265@1,COG0265@2 NA|NA|NA O Belongs to the peptidase S1C family HFDCGJPN_00720 582744.Msip34_0278 9.6e-95 353.2 Nitrosomonadales tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1MVAY@1224,2KKP5@206350,2VI2H@28216,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides HFDCGJPN_00721 582744.Msip34_0277 9.1e-22 109.8 Nitrosomonadales tatB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1N73F@1224,2KN8S@206350,2VVPX@28216,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation HFDCGJPN_00722 582744.Msip34_0276 4.7e-18 96.7 Nitrosomonadales tatA GO:0003674,GO:0005215 ko:K03116,ko:K03425 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1N6S4@1224,2KN9D@206350,2VVT6@28216,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system HFDCGJPN_00723 583345.Mmol_0320 9.7e-50 202.6 Nitrosomonadales hinT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.1.226,2.1.1.227 ko:K02503,ko:K06442 ko00000,ko01000,ko03009,ko04147 Bacteria 1RDCJ@1224,2KMXF@206350,2VSMS@28216,COG0537@1,COG0537@2 NA|NA|NA FG PFAM histidine triad (HIT) protein HFDCGJPN_00724 1132855.KB913035_gene2520 2.7e-41 174.5 Nitrosomonadales hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria 1MZEE@1224,2KMX7@206350,2VUN8@28216,COG0140@1,COG0140@2 NA|NA|NA E PFAM phosphoribosyl-ATP pyrophosphohydrolase HFDCGJPN_00725 1236959.BAMT01000006_gene446 1.2e-61 242.3 Nitrosomonadales hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 iJN746.PP_5014 Bacteria 1MW67@1224,2KMS4@206350,2VR9B@28216,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP HFDCGJPN_00726 582744.Msip34_0272 6.8e-123 446.8 Nitrosomonadales hisF GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUS0@1224,2KM4T@206350,2VHY0@28216,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit HFDCGJPN_00727 582744.Msip34_0271 2.5e-127 461.5 Nitrosomonadales hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1MW6S@1224,2KKGM@206350,2VI38@28216,COG0106@1,COG0106@2 NA|NA|NA E TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HFDCGJPN_00728 582744.Msip34_0270 3.1e-89 334.7 Nitrosomonadales hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4X@1224,2KKPZ@206350,2VJPI@28216,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR HFDCGJPN_00729 582744.Msip34_0269 1.5e-98 365.5 Nitrosomonadales hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1MWBS@1224,2KKWP@206350,2VI59@28216,COG0131@1,COG0131@2 NA|NA|NA E PFAM Imidazoleglycerol-phosphate dehydratase HFDCGJPN_00730 583345.Mmol_0313 6.6e-106 390.2 Nitrosomonadales rmpA 4.1.2.43,5.3.1.27 ko:K08093,ko:K13831 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338,R05339,R09780 RC00377,RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 Bacteria 1R970@1224,2KKJK@206350,2VWTN@28216,COG0269@1,COG0269@2 NA|NA|NA G PFAM Orotidine 5'-phosphate decarboxylase HFDCGJPN_00731 582744.Msip34_0267 6.1e-159 567.0 Nitrosomonadales hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 iJN678.hisC Bacteria 1MW7I@1224,2KM3F@206350,2VHFU@28216,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily HFDCGJPN_00732 1132855.KB913035_gene2528 2.4e-213 748.0 Nitrosomonadales hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iYO844.BSU34910 Bacteria 1MUUF@1224,2KM6F@206350,2VJ7K@28216,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine HFDCGJPN_00733 265072.Mfla_0247 7.1e-102 376.7 Nitrosomonadales hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUCY@1224,2KM3E@206350,2VIF9@28216,COG0040@1,COG0040@2 NA|NA|NA E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity HFDCGJPN_00734 583345.Mmol_0309 1.6e-190 672.2 Nitrosomonadales murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1MUH7@1224,2KKQE@206350,2VHZN@28216,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine HFDCGJPN_00735 1236959.BAMT01000006_gene435 9.6e-44 182.6 Nitrosomonadales grxD ko:K07390 ko00000,ko03029,ko03110 Bacteria 1MZ4V@1224,2KN32@206350,2VSCX@28216,COG0278@1,COG0278@2 NA|NA|NA C Glutaredoxin HFDCGJPN_00736 582744.Msip34_0262 5.6e-31 139.8 Nitrosomonadales yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 Bacteria 1MZCZ@1224,2KN4E@206350,2VU0K@28216,COG5007@1,COG5007@2 NA|NA|NA K Belongs to the BolA IbaG family HFDCGJPN_00737 582744.Msip34_0261 9.3e-109 399.8 Nitrosomonadales yadH ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MUH1@1224,2KKDW@206350,2VH42@28216,COG0842@1,COG0842@2 NA|NA|NA V PFAM ABC-2 type transporter HFDCGJPN_00738 1236959.BAMT01000006_gene432 1.5e-134 485.7 Nitrosomonadales yadG ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 Bacteria 1MUW7@1224,2KKJG@206350,2VI81@28216,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter HFDCGJPN_00739 1236959.BAMT01000006_gene431 3.7e-21 107.5 Nitrosomonadales ko:K07122 ko02010,map02010 M00210 ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 Bacteria 1NGIE@1224,2KNBR@206350,2W81J@28216,COG3113@1,COG3113@2 NA|NA|NA S STAS domain HFDCGJPN_00740 582744.Msip34_0258 6.6e-81 307.0 Nitrosomonadales mlaC GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0015711,GO:0015748,GO:0015914,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009,GO:0120010 ko:K07323 ko02010,map02010 M00210 ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 Bacteria 1NKFA@1224,2KME2@206350,2VR85@28216,COG2854@1,COG2854@2 NA|NA|NA Q PFAM toluene tolerance HFDCGJPN_00741 582744.Msip34_0257 1.9e-67 261.9 Nitrosomonadales mlaD GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1NCUG@1224,2KMJU@206350,2VRKR@28216,COG1463@1,COG1463@2 NA|NA|NA Q PFAM Mammalian cell entry related domain protein HFDCGJPN_00742 582744.Msip34_0256 1.1e-125 456.1 Nitrosomonadales mlaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MVPN@1224,2KKIQ@206350,2VI5T@28216,COG0767@1,COG0767@2 NA|NA|NA Q Permease MlaE HFDCGJPN_00743 582744.Msip34_0255 3.6e-135 487.6 Nitrosomonadales mlaF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1MUSD@1224,2KKNS@206350,2VJIA@28216,COG1127@1,COG1127@2 NA|NA|NA Q PFAM ABC transporter HFDCGJPN_00744 1502770.JQMG01000001_gene1109 3.2e-70 271.6 Nitrosomonadales ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1REMT@1224,2KMRF@206350,2VR8U@28216,COG2165@1,COG2165@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif HFDCGJPN_00745 987059.RBXJA2T_00849 4.1e-27 127.9 Betaproteobacteria Bacteria 1N8BM@1224,2E92A@1,2VW75@28216,333BE@2 NA|NA|NA HFDCGJPN_00746 666681.M301_1026 1.3e-264 918.7 Nitrosomonadales etf GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 ko:K00311 ko00000,ko01000 Bacteria 1MVU6@1224,2KMI8@206350,2VH37@28216,COG0644@1,COG0644@2,COG2440@1,COG2440@2 NA|NA|NA C PFAM electron transfer flavoprotein-ubiquinone oxidoreductase HFDCGJPN_00747 1165096.ARWF01000001_gene1070 1.8e-146 525.4 Nitrosomonadales yeiE Bacteria 1MWVU@1224,2KMCC@206350,2VHCI@28216,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family HFDCGJPN_00748 1165096.ARWF01000001_gene1071 9.5e-106 389.8 Nitrosomonadales etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K03521 ko00000 Bacteria 1MVH6@1224,2KKVA@206350,2VHXJ@28216,COG2086@1,COG2086@2 NA|NA|NA C PFAM Electron transfer flavoprotein HFDCGJPN_00749 666681.M301_1023 1.6e-123 449.1 Nitrosomonadales etfA ko:K03522 ko00000,ko04147 Bacteria 1MUFI@1224,2KM91@206350,2VI6W@28216,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein, alpha subunit HFDCGJPN_00750 666681.M301_1022 5.2e-131 473.8 Nitrosomonadales fpr 1.18.1.2,1.19.1.1 ko:K00528,ko:K05784 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110,R10159 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 1MW37@1224,2KKM0@206350,2WGQC@28216,COG1018@1,COG1018@2 NA|NA|NA C PFAM oxidoreductase FAD NAD(P)-binding domain protein HFDCGJPN_00753 1217718.ALOU01000052_gene3044 4.8e-15 87.8 Betaproteobacteria Bacteria 1RKBI@1224,2VWK7@28216,COG3305@1,COG3305@2 NA|NA|NA S Predicted membrane protein (DUF2127) HFDCGJPN_00755 640081.Dsui_0754 3.6e-31 141.0 Rhodocyclales Bacteria 1NNNA@1224,2AIB9@1,2KZMP@206389,2W5SH@28216,33HJY@2 NA|NA|NA HFDCGJPN_00756 614083.AWQR01000022_gene119 4e-105 389.0 Comamonadaceae 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1PRTS@1224,2VM82@28216,4AIP0@80864,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family HFDCGJPN_00757 265072.Mfla_0894 6.1e-20 103.2 Betaproteobacteria Bacteria 1NJ3D@1224,2EKBB@1,2VXMB@28216,33E1Q@2 NA|NA|NA HFDCGJPN_00758 312153.Pnuc_1610 1.5e-37 162.2 Burkholderiaceae Bacteria 1K9H8@119060,1MZVF@1224,2VUS5@28216,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases HFDCGJPN_00759 1454004.AW11_02382 2.7e-23 115.9 Betaproteobacteria addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1QUUZ@1224,2WI1S@28216,COG1074@1,COG1074@2 NA|NA|NA L PDDEXK-like domain of unknown function (DUF3799) HFDCGJPN_00760 1101195.Meth11DRAFT_0226 9.3e-133 479.9 Nitrosomonadales 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUXZ@1224,2KMIJ@206350,2VR06@28216,COG0753@1,COG0753@2 NA|NA|NA P Has an organic peroxide-dependent peroxidase activity HFDCGJPN_00761 1132855.KB913035_gene797 5.5e-80 304.7 Proteobacteria phoA 3.1.3.2 ko:K14379 ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323 R00548 RC00017 ko00000,ko00001,ko01000 Bacteria 1NXRI@1224,COG1409@1,COG1409@2 NA|NA|NA N acid phosphatase HFDCGJPN_00762 1236959.BAMT01000005_gene224 2.1e-100 372.5 Nitrosomonadales Bacteria 1RHDT@1224,2KKD2@206350,2VTTP@28216,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function, DUF481 HFDCGJPN_00763 1095769.CAHF01000006_gene1949 3.4e-44 184.9 Betaproteobacteria Bacteria 1RH4S@1224,2VRI3@28216,COG2258@1,COG2258@2 NA|NA|NA S MOSC domain HFDCGJPN_00764 395494.Galf_0056 4.6e-22 110.5 Betaproteobacteria Bacteria 1N6VS@1224,2C84F@1,2VWHA@28216,334ZR@2 NA|NA|NA HFDCGJPN_00765 314278.NB231_09368 5.1e-17 95.5 Gammaproteobacteria 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315,ko:K20977 ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213 M00695,M00820 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02022,ko03021 Bacteria 1MV1V@1224,1RYBQ@1236,COG2114@1,COG2114@2,COG3437@1,COG3437@2 NA|NA|NA T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) HFDCGJPN_00766 582744.Msip34_2741 1.3e-11 77.0 Nitrosomonadales ko:K07126 ko00000 Bacteria 1MWPA@1224,2KNAX@206350,2VM3A@28216,COG0790@1,COG0790@2 NA|NA|NA S Sel1-like repeats. HFDCGJPN_00767 582744.Msip34_2726 1e-128 466.5 Nitrosomonadales Bacteria 1MUDK@1224,2KN50@206350,2WF3J@28216,COG4977@1,COG4977@2 NA|NA|NA K helix-turn-helix- domain containing protein, AraC type HFDCGJPN_00768 582744.Msip34_2725 1.6e-95 355.9 Nitrosomonadales ko:K07124 ko00000 Bacteria 1MWNZ@1224,2KMAG@206350,2VPX6@28216,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family HFDCGJPN_00769 666681.M301_2689 1e-10 72.4 Nitrosomonadales Bacteria 1NGBT@1224,2EH60@1,2KND7@206350,2W81Z@28216,33AXW@2 NA|NA|NA S Protein of unknown function (DUF2798) HFDCGJPN_00770 1132855.KB913035_gene76 1.8e-45 188.3 Nitrosomonadales ko:K06995 ko00000 Bacteria 1N8CD@1224,2KN1D@206350,2W7ZV@28216,COG3450@1,COG3450@2 NA|NA|NA S Protein of unknown function (DUF861) HFDCGJPN_00771 1198232.CYCME_1828 1.9e-28 132.5 Thiotrichales ybeL 1.17.4.1,4.6.1.1 ko:K00525,ko:K01768 ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213 M00053,M00695 R00089,R00434,R02017,R02018,R02019,R02024 RC00295,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1P9T7@1224,1RYIB@1236,460Y8@72273,COG2888@1,COG2888@2 NA|NA|NA J Zinc-ribbon containing domain HFDCGJPN_00772 1132855.KB913035_gene79 3.9e-83 315.1 Nitrosomonadales Bacteria 1PJNT@1224,2BUPG@1,2KNHN@206350,2W82M@28216,32Q0G@2 NA|NA|NA HFDCGJPN_00773 1387312.BAUS01000004_gene1692 3.3e-45 187.6 Nitrosomonadales yneG Bacteria 1RGW8@1224,2DMJC@1,2KMYS@206350,2VVIM@28216,32RYJ@2 NA|NA|NA S Domain of unknown function (DUF4186) HFDCGJPN_00774 420662.Mpe_A1369 7.8e-94 350.5 unclassified Burkholderiales yedI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K09781 ko00000 Bacteria 1KJK3@119065,1MVYU@1224,2VHTU@28216,COG2354@1,COG2354@2 NA|NA|NA S Protein of unknown function (DUF808) HFDCGJPN_00775 582744.Msip34_2477 1.1e-87 330.1 Nitrosomonadales ko:K18900 M00698 ko00000,ko00002,ko01504,ko03000 Bacteria 1MV06@1224,2KKMP@206350,2VHGD@28216,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain HFDCGJPN_00776 163908.KB235896_gene4833 5.6e-90 337.4 Nostocales Bacteria 1G604@1117,1HMRT@1161,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase HFDCGJPN_00778 1366050.N234_11210 4.8e-104 384.4 Burkholderiaceae crgA Bacteria 1K0MI@119060,1MU7H@1224,2VISY@28216,COG0583@1,COG0583@2 NA|NA|NA K LysR family HFDCGJPN_00779 582744.Msip34_1415 8.2e-92 343.6 Nitrosomonadales Bacteria 1MUWC@1224,2KNHY@206350,2VK5Z@28216,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain HFDCGJPN_00780 265072.Mfla_2609 5.1e-46 191.0 Nitrosomonadales scrK 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1PCFU@1224,2KMJK@206350,2VK5G@28216,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase HFDCGJPN_00782 1101195.Meth11DRAFT_0409 4.5e-99 367.5 Nitrosomonadales radC ko:K03630 ko00000 Bacteria 1MXZ5@1224,2KKTE@206350,2VKTW@28216,COG2003@1,COG2003@2 NA|NA|NA L TIGRFAM DNA repair protein RadC HFDCGJPN_00784 1122236.KB905145_gene2502 4.7e-108 398.7 Nitrosomonadales Bacteria 1MWEC@1224,2KNWM@206350,2VJXF@28216,COG2831@1,COG2831@2 NA|NA|NA U Haemolysin secretion/activation protein ShlB/FhaC/HecB HFDCGJPN_00785 1101195.Meth11DRAFT_2530 1.3e-110 406.0 Nitrosomonadales gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1MUKG@1224,2KKUJ@206350,2VI3A@28216,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) HFDCGJPN_00788 1266925.JHVX01000003_gene440 1.9e-137 495.7 Nitrosomonadales cmeA ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 1MU78@1224,2VINC@28216,371V6@32003,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_00789 583345.Mmol_0883 4.8e-38 164.1 Nitrosomonadales Bacteria 1PJGW@1224,2A8J8@1,2KMZV@206350,2W7ZN@28216,30XMH@2 NA|NA|NA HFDCGJPN_00790 582744.Msip34_1701 8e-233 812.8 Nitrosomonadales rimO 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 1MU7N@1224,2KMFV@206350,2VI16@28216,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 HFDCGJPN_00791 582744.Msip34_1702 2.2e-18 97.8 Nitrosomonadales Bacteria 1N9R9@1224,2E3TT@1,2KNYQ@206350,2VW0P@28216,32YR7@2 NA|NA|NA HFDCGJPN_00792 1101195.Meth11DRAFT_0988 1.1e-102 379.8 Nitrosomonadales ko:K11021,ko:K16267 ko00000,ko02000,ko02042 2.A.5.4.11 Bacteria 1R40E@1224,2KKCZ@206350,2VN69@28216,COG0428@1,COG0428@2 NA|NA|NA P ZIP Zinc transporter HFDCGJPN_00793 265072.Mfla_1611 1.2e-92 346.3 Nitrosomonadales yfiH ko:K05810 ko00000,ko01000 Bacteria 1MW2H@1224,2KKNJ@206350,2VKD4@28216,COG1496@1,COG1496@2 NA|NA|NA S Belongs to the multicopper oxidase YfiH RL5 family HFDCGJPN_00794 582744.Msip34_1708 1.2e-143 516.2 Nitrosomonadales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1MUBN@1224,2KKXP@206350,2VIFF@28216,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil HFDCGJPN_00795 582744.Msip34_1709 1.1e-123 449.5 Nitrosomonadales bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria 1MVS5@1224,2KKI6@206350,2VH6I@28216,COG4105@1,COG4105@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HFDCGJPN_00796 582744.Msip34_1710 2.5e-238 831.2 Nitrosomonadales der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 ko:K03977 ko00000,ko03009 Bacteria 1MU9S@1224,2KKDH@206350,2VI8D@28216,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis HFDCGJPN_00797 582744.Msip34_1711 6.3e-165 587.0 Nitrosomonadales bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K17713 ko00000,ko02000 1.B.33.1 Bacteria 1MXIJ@1224,2KKMY@206350,2VHH5@28216,COG1520@1,COG1520@2 NA|NA|NA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HFDCGJPN_00798 582744.Msip34_1712 3.4e-64 251.5 Nitrosomonadales yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 Bacteria 1N117@1224,2KMWQ@206350,2VSHE@28216,COG2976@1,COG2976@2 NA|NA|NA S Tetratricopeptide repeat-like domain HFDCGJPN_00799 666681.M301_0921 1.2e-109 402.9 Nitrosomonadales ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1NU4K@1224,2KMCQ@206350,2W19X@28216,COG4608@1,COG4608@2 NA|NA|NA E PFAM ABC transporter HFDCGJPN_00800 582744.Msip34_1714 1.9e-123 448.7 Nitrosomonadales dppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1R4KB@1224,2KKGX@206350,2W0NK@28216,COG0444@1,COG0444@2 NA|NA|NA EP Belongs to the ABC transporter superfamily HFDCGJPN_00801 1132855.KB913035_gene1867 2.3e-197 694.9 Nitrosomonadales hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358 Bacteria 1MV2K@1224,2KKZY@206350,2VIGA@28216,COG0124@1,COG0124@2 NA|NA|NA J PFAM tRNA synthetase class II (G H P and S) HFDCGJPN_00802 582744.Msip34_1716 4.2e-202 710.7 Nitrosomonadales ispG GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iJN678.gcpE Bacteria 1MUAX@1224,2KMH4@206350,2VID7@28216,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate HFDCGJPN_00803 265072.Mfla_1621 6.5e-50 204.5 Nitrosomonadales ko:K15539 ko00000 Bacteria 1N240@1224,2KN0N@206350,2VVFV@28216,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain HFDCGJPN_00804 582744.Msip34_1718 3.7e-78 298.1 Nitrosomonadales pilF ko:K02656 ko00000,ko02035,ko02044 Bacteria 1MXPC@1224,2KMND@206350,2VNC8@28216,COG3063@1,COG3063@2 NA|NA|NA NU TIGRFAM type IV pilus biogenesis stability protein PilW HFDCGJPN_00805 1101195.Meth11DRAFT_0976 1e-180 639.4 Nitrosomonadales rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 1MUYK@1224,2KM5F@206350,2VIBN@28216,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs HFDCGJPN_00806 1122236.KB905141_gene1063 4.6e-62 243.8 Nitrosomonadales ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1R9ZA@1224,2KMJQ@206350,2VQ2J@28216,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate HFDCGJPN_00807 582744.Msip34_1721 1.1e-54 219.2 Nitrosomonadales rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K22132 ko00000,ko01000,ko03009,ko03016 Bacteria 1MWCM@1224,2KKG5@206350,2VHF4@28216,COG0566@1,COG0566@2 NA|NA|NA J Specifically methylates the ribose of guanosine 2251 in 23S rRNA HFDCGJPN_00808 1236959.BAMT01000003_gene567 4.2e-72 277.3 Nitrosomonadales cysM GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738,ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUBE@1224,2KMC4@206350,2VH7B@28216,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family HFDCGJPN_00809 582744.Msip34_0942 8.1e-124 449.9 Nitrosomonadales wlaX ko:K07501 ko00000 Bacteria 1MVZJ@1224,2KKD0@206350,2VISP@28216,COG3298@1,COG3298@2 NA|NA|NA L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB HFDCGJPN_00810 582744.Msip34_2765 1.5e-88 332.8 Nitrosomonadales ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1MY0I@1224,2KKH7@206350,2VKTC@28216,COG0668@1,COG0668@2 NA|NA|NA M Mechanosensitive ion channel HFDCGJPN_00811 582744.Msip34_2764 7.1e-294 1016.1 Nitrosomonadales ams 2.4.1.4,3.2.1.1,5.4.99.16 ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 GH13 Bacteria 1MVKX@1224,2KKFD@206350,2VM7M@28216,COG0366@1,COG0366@2 NA|NA|NA G Glycogen debranching enzyme, glucanotransferase domain HFDCGJPN_00812 582744.Msip34_2763 1.9e-303 1048.1 Nitrosomonadales sps GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246,3.1.3.24,3.1.3.79 ko:K00696,ko:K07024,ko:K13058,ko:K13086 ko00500,ko01100,map00500,map01100 R00766,R00805,R06211,R08947,R08982 RC00005,RC00017,RC00028,RC02748 ko00000,ko00001,ko01000 GT4 Bacteria 1MWVX@1224,2KKNC@206350,2VN6U@28216,COG0438@1,COG0438@2,COG0561@1,COG0561@2 NA|NA|NA M Sucrose-6F-phosphate phosphohydrolase HFDCGJPN_00813 265072.Mfla_2609 2.1e-102 379.0 Nitrosomonadales scrK 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1PCFU@1224,2KMJK@206350,2VK5G@28216,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase HFDCGJPN_00814 1165096.ARWF01000001_gene1367 4.7e-35 154.5 Betaproteobacteria Bacteria 1PW9W@1224,2VUDE@28216,COG1846@1,COG1846@2 NA|NA|NA K MarR family HFDCGJPN_00815 338969.Rfer_1828 2.1e-19 101.7 Comamonadaceae lonD 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1RFYH@1224,2VSA4@28216,4ADGM@80864,COG2802@1,COG2802@2 NA|NA|NA S PFAM peptidase S16 lon domain protein HFDCGJPN_00816 582744.Msip34_0532 1.8e-183 648.7 Nitrosomonadales cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1MV60@1224,2KMI4@206350,2VHFR@28216,COG1271@1,COG1271@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit I HFDCGJPN_00817 582744.Msip34_0531 8.9e-180 636.3 Nitrosomonadales cydB 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iYO844.BSU38750 Bacteria 1MURP@1224,2KMGQ@206350,2VHSQ@28216,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit II HFDCGJPN_00818 582744.Msip34_0530 8.2e-10 68.6 Betaproteobacteria ybgT GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019867,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0071944 1.10.3.14 ko:K00424 ko00190,ko02020,map00190,map02020 M00153 ko00000,ko00001,ko01000 3.D.4.3 Bacteria 1NGDQ@1224,2VYT0@28216,COG4890@1,COG4890@2 NA|NA|NA S membrane HFDCGJPN_00819 1101195.Meth11DRAFT_0596 1.2e-104 386.0 Nitrosomonadales yuiH Bacteria 1MWZK@1224,2KKZK@206350,2VQA6@28216,COG2041@1,COG2041@2 NA|NA|NA S PFAM oxidoreductase molybdopterin binding HFDCGJPN_00820 582744.Msip34_0522 4.4e-61 240.7 Nitrosomonadales lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1RGV9@1224,2KMS9@206350,2VSEP@28216,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins HFDCGJPN_00821 1502770.JQMG01000001_gene314 0.0 1657.1 Nitrosomonadales ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1MVBQ@1224,2KKY2@206350,2VIEJ@28216,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) HFDCGJPN_00822 666681.M301_0538 1.8e-84 318.9 Nitrosomonadales ribF GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0025,iJN746.PP_0602 Bacteria 1MV9I@1224,2KMHC@206350,2VHIP@28216,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family HFDCGJPN_00823 582744.Msip34_1879 2.8e-186 657.9 Nitrosomonadales carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1950,iNJ661.Rv1383,iUTI89_1310.UTI89_C0036,ic_1306.c0040 Bacteria 1MUB9@1224,2KMEN@206350,2VH9Q@28216,COG0505@1,COG0505@2 NA|NA|NA EF TIGRFAM carbamoyl-phosphate synthase, small subunit HFDCGJPN_00824 1538295.JY96_10095 3.2e-51 209.1 unclassified Burkholderiales Bacteria 1KNJE@119065,1MZV7@1224,2VUP7@28216,COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_00825 582744.Msip34_1880 1.6e-114 419.1 Nitrosomonadales dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215,ko:K03546 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000,ko03400 iIT341.HP0510,iLJ478.TM1520,iSbBS512_1146.SbBS512_E0035 Bacteria 1MUCT@1224,2KKZJ@206350,2VJC3@28216,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate HFDCGJPN_00826 265072.Mfla_0776 5.5e-40 171.4 Nitrosomonadales bamE 3.4.16.4 ko:K01286,ko:K03642,ko:K06186,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011,ko02000 1.B.33.1 Bacteria 1N6YW@1224,2KMV2@206350,2VRC6@28216,COG2913@1,COG2913@2,COG3087@1,COG3087@2 NA|NA|NA J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HFDCGJPN_00827 582744.Msip34_1882 2.5e-63 248.1 Nitrosomonadales fur ko:K03711 ko00000,ko03000 Bacteria 1RDWJ@1224,2KMNR@206350,2VR52@28216,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family HFDCGJPN_00828 1236959.BAMT01000001_gene1032 3.5e-201 708.0 Nitrosomonadales recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03631 ko00000,ko03400 Bacteria 1MUNP@1224,2KMFA@206350,2VHHA@28216,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA HFDCGJPN_00829 582744.Msip34_1884 7.6e-107 393.7 Nitrosomonadales nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1MUBC@1224,2KM1M@206350,2VIV0@28216,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP HFDCGJPN_00830 583345.Mmol_1713 6.9e-217 760.4 Betaproteobacteria yejM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07014 ko00000 Bacteria 1MX6X@1224,2VJH1@28216,COG3083@1,COG3083@2 NA|NA|NA S Domain of unknown function (DUF3413) HFDCGJPN_00831 582744.Msip34_1885 4.2e-157 560.8 Nitrosomonadales hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1MVX4@1224,2KKME@206350,2VHCK@28216,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons HFDCGJPN_00832 582744.Msip34_1886 4.1e-50 205.3 Betaproteobacteria Bacteria 1RJ1B@1224,2VTGM@28216,COG5581@1,COG5581@2 NA|NA|NA M type IV pilus assembly PilZ HFDCGJPN_00833 582744.Msip34_1887 1e-161 576.2 Nitrosomonadales hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVR1@1224,2KKWT@206350,2VH7Z@28216,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX HFDCGJPN_00834 582744.Msip34_1888 3.6e-145 521.2 Nitrosomonadales hldD 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MVE4@1224,2KKPF@206350,2VH69@28216,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose HFDCGJPN_00835 582744.Msip34_1889 9.3e-75 286.6 Nitrosomonadales gmhA 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1NJ8X@1224,2KMGZ@206350,2VN12@28216,COG0279@1,COG0279@2 NA|NA|NA G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate HFDCGJPN_00836 265072.Mfla_0855 1e-277 962.2 Nitrosomonadales nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 Bacteria 1RBQW@1224,2KMAD@206350,2VHA7@28216,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate HFDCGJPN_00837 582744.Msip34_1787 1.9e-100 372.1 Nitrosomonadales rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 1MX7T@1224,2KKVH@206350,2VHR2@28216,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase sigma factor, sigma-70 family HFDCGJPN_00838 582744.Msip34_1786 2.4e-43 181.8 Nitrosomonadales rseA GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 ko:K03597 ko00000,ko03021 Bacteria 1QANZ@1224,2KN4N@206350,2VVPR@28216,COG3073@1,COG3073@2 NA|NA|NA T PFAM Anti sigma-E protein RseA HFDCGJPN_00839 582744.Msip34_1785 2.4e-109 402.1 Nitrosomonadales rseB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 ko:K03598 ko00000,ko03021 Bacteria 1MUQ8@1224,2KKK1@206350,2VMZQ@28216,COG3026@1,COG3026@2 NA|NA|NA T MucB/RseB C-terminal domain HFDCGJPN_00840 666681.M301_1953 1.2e-29 136.3 Nitrosomonadales rseC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 ko:K03803 ko00000,ko03021 Bacteria 1PVB3@1224,2KNVG@206350,2VYDY@28216,COG3086@1,COG3086@2 NA|NA|NA T PFAM Positive regulator of sigma(E) RseC MucC HFDCGJPN_00841 582744.Msip34_1784 5.3e-206 723.8 Nitrosomonadales mucD 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU63@1224,2KKP9@206350,2VI4Q@28216,COG0265@1,COG0265@2 NA|NA|NA M Belongs to the peptidase S1C family HFDCGJPN_00842 1236959.BAMT01000008_gene2451 3.5e-97 360.9 Nitrosomonadales Bacteria 1MWYS@1224,2KKMJ@206350,2VNIQ@28216,COG1795@1,COG1795@2 NA|NA|NA S PFAM Formaldehyde-activating enzyme (Fae) HFDCGJPN_00843 1236959.BAMT01000008_gene2450 1.4e-37 162.5 Nitrosomonadales ko:K02348 ko00000 Bacteria 1MZ86@1224,2KN42@206350,2VMR6@28216,COG2153@1,COG2153@2 NA|NA|NA S Acetyltransferase (GNAT) domain HFDCGJPN_00845 1101195.Meth11DRAFT_2501 5.1e-31 140.6 Nitrosomonadales yqjF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15977 ko00000 Bacteria 1P2FD@1224,2KN7E@206350,2W4SE@28216,COG2259@1,COG2259@2 NA|NA|NA S DoxX HFDCGJPN_00846 265072.Mfla_2431 4.3e-148 530.8 Nitrosomonadales ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iIT341.HP0400,iLJ478.TM1444,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 Bacteria 1MU7G@1224,2KM0H@206350,2VHM8@28216,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis HFDCGJPN_00847 582744.Msip34_2603 3.3e-116 424.9 Nitrosomonadales cobD GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWCK@1224,2KNPK@206350,2VH7X@28216,COG1270@1,COG1270@2 NA|NA|NA H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group HFDCGJPN_00848 1236959.BAMT01000008_gene2444 2.2e-46 192.2 Nitrosomonadales yhgE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K13652 ko00000,ko03000 Bacteria 1N79X@1224,2KNU0@206350,2VWWR@28216,COG3449@1,COG3449@2 NA|NA|NA L Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell HFDCGJPN_00849 1236959.BAMT01000008_gene2443 2.3e-140 505.0 Nitrosomonadales purU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.72,3.5.1.10 ko:K00974,ko:K01433 ko00630,ko00670,ko03013,map00630,map00670,map03013 R00944,R09382,R09383,R09384,R09386 RC00026,RC00078,RC00111 ko00000,ko00001,ko01000,ko03016 iSDY_1059.SDY_1284 Bacteria 1MVCF@1224,2KM5N@206350,2VIXE@28216,COG0788@1,COG0788@2 NA|NA|NA F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) HFDCGJPN_00850 265072.Mfla_2443 4.6e-190 670.6 Nitrosomonadales lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 ko:K01586,ko:K05366 ko00300,ko00550,ko01100,ko01110,ko01120,ko01130,ko01230,ko01501,map00300,map00550,map01100,map01110,map01120,map01130,map01230,map01501 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000,ko01003,ko01011 GT51 iLJ478.TM1517 Bacteria 1MUA6@1224,2KKUY@206350,2VI3M@28216,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine HFDCGJPN_00851 1095769.CAHF01000006_gene1974 9e-37 159.8 Oxalobacteraceae ko:K02650,ko:K02655 ko02020,map02020 ko00000,ko00001,ko02035,ko02044 3.A.15.2 Bacteria 1MZZW@1224,2VU8H@28216,474VK@75682,COG4968@1,COG4968@2 NA|NA|NA NU Type IV minor pilin ComP, DNA uptake sequence receptor HFDCGJPN_00852 1095769.CAHF01000006_gene1975 1.2e-29 136.7 Oxalobacteraceae ko:K02456,ko:K08084 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.15.2 Bacteria 1NA9B@1224,2VWAB@28216,4751F@75682,COG4970@1,COG4970@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif HFDCGJPN_00853 1095769.CAHF01000006_gene1976 1.6e-24 119.4 Oxalobacteraceae pilV ko:K02671 ko00000,ko02035,ko02044 Bacteria 1N7AC@1224,2VW8B@28216,4755Z@75682,COG4967@1,COG4967@2 NA|NA|NA NU type IV pilus modification protein PilV HFDCGJPN_00854 1538295.JY96_13155 2.8e-74 285.8 Betaproteobacteria ko:K02672 ko00000,ko02035,ko02044 Bacteria 1RH2G@1224,2VT5C@28216,COG4966@1,COG4966@2 NA|NA|NA NU Type IV Pilus-assembly protein W HFDCGJPN_00855 1095769.CAHF01000006_gene1978 2e-37 162.5 Oxalobacteraceae ko:K02673 ko00000,ko02035,ko02044 Bacteria 1N9CE@1224,2VWPP@28216,47556@75682,COG4726@1,COG4726@2 NA|NA|NA NU Pilus assembly protein PilX HFDCGJPN_00856 1454004.AW11_01622 0.0 1104.4 Betaproteobacteria pilY1 ko:K02674 ko00000,ko02035,ko02044 Bacteria 1NUAV@1224,2VHY8@28216,COG2304@1,COG2304@2,COG3419@1,COG3419@2 NA|NA|NA NU pilus assembly protein tip-associated adhesin HFDCGJPN_00857 1502770.JQMG01000001_gene747 3.8e-56 224.6 Nitrosomonadales hepS 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 R09247 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1RJIB@1224,2KNRZ@206350,2VRM1@28216,COG4769@1,COG4769@2 NA|NA|NA S Heptaprenyl diphosphate synthase component I HFDCGJPN_00858 1502770.JQMG01000001_gene746 3.2e-36 157.9 Nitrosomonadales Bacteria 1N1PN@1224,2KNV8@206350,2VUW8@28216,COG5341@1,COG5341@2 NA|NA|NA S NusG domain II HFDCGJPN_00859 1502770.JQMG01000001_gene745 6.5e-105 387.5 Nitrosomonadales rnfF 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1MW6K@1224,2KNMN@206350,2VPGP@28216,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein HFDCGJPN_00860 1101195.Meth11DRAFT_2544 2e-124 452.2 Nitrosomonadales gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0042601,GO:0042763,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2,6.3.2.3 ko:K01919,ko:K01920,ko:K05844 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R00894,R10993,R10994 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko03009 iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 Bacteria 1MVUA@1224,2KM28@206350,2VIZ3@28216,COG0189@1,COG0189@2 NA|NA|NA HJ Belongs to the prokaryotic GSH synthase family HFDCGJPN_00861 582744.Msip34_2591 6.2e-214 750.0 Nitrosomonadales secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 ko:K01919,ko:K03072,ko:K12257 ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070 M00118,M00335 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1MVFS@1224,2KKJP@206350,2VHD9@28216,COG0342@1,COG0342@2 NA|NA|NA U PFAM Glutamate-cysteine ligase HFDCGJPN_00862 666681.M301_2642 9e-225 786.2 Nitrosomonadales amtB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015291,GO:0015292,GO:0015669,GO:0015670,GO:0015696,GO:0015893,GO:0016020,GO:0016021,GO:0019755,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098655 ko:K03320 ko00000,ko02000 1.A.11 iEcE24377_1341.EcE24377A_0487 Bacteria 1NR9F@1224,2KKII@206350,2VJ8B@28216,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter HFDCGJPN_00863 582744.Msip34_2589 1.1e-53 215.7 Nitrosomonadales glnK ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 1RGWK@1224,2KMRE@206350,2VSEZ@28216,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family HFDCGJPN_00864 1000565.METUNv1_00315 2.3e-92 345.5 Rhodocyclales Bacteria 1RGNG@1224,2C5U9@1,2KYRP@206389,2VS67@28216,30VS0@2 NA|NA|NA S Bacterial protein of unknown function (Gcw_chp) HFDCGJPN_00865 1101195.Meth11DRAFT_1073 1.8e-89 335.5 Nitrosomonadales MA20_18170 ko:K07090 ko00000 Bacteria 1MWX2@1224,2KKR2@206350,2VMUD@28216,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE HFDCGJPN_00866 59538.XP_005974328.1 1.9e-303 1047.7 Eukaryota NIR GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0010035,GO:0010167,GO:0016020,GO:0016491,GO:0016661,GO:0016662,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0050421,GO:0050896,GO:0055114,GO:0098809,GO:1901698,GO:1901700 1.7.7.1 ko:K00366 ko00910,ko01120,map00910,map01120 M00531 R00790 RC00176 ko00000,ko00001,ko00002,ko01000 Eukaryota COG0155@1,KOG0560@2759 NA|NA|NA P sulfite reductase (ferredoxin) activity HFDCGJPN_00867 1101195.Meth11DRAFT_1071 7.3e-88 330.1 Nitrosomonadales MA20_18215 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 Bacteria 1RJR9@1224,2KKUK@206350,2VSQB@28216,COG3749@1,COG3749@2 NA|NA|NA S Bacterial protein of unknown function (DUF934) HFDCGJPN_00868 1101195.Meth11DRAFT_1070 2.2e-118 431.8 Nitrosomonadales cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25 ko:K00366,ko:K00390,ko:K00860 ko00230,ko00910,ko00920,ko01100,ko01120,map00230,map00910,map00920,map01100,map01120 M00176,M00531 R00509,R00790,R02021,R04928 RC00002,RC00007,RC00078,RC00176,RC02862 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXUR@1224,2KMCD@206350,2VIR0@28216,COG0175@1,COG0175@2 NA|NA|NA EH Reduction of activated sulfate into sulfite HFDCGJPN_00869 1112274.KI911560_gene2056 3.4e-169 600.9 Nitrosomonadales cysD 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUCZ@1224,2KM7X@206350,2VJH9@28216,COG0175@1,COG0175@2 NA|NA|NA EH PFAM Phosphoadenosine phosphosulfate reductase HFDCGJPN_00874 582744.Msip34_1239 3.2e-260 904.8 Nitrosomonadales lidB 3.1.11.5 ko:K01144 ko00000,ko01000 Bacteria 1QU90@1224,2KMEP@206350,2VHNR@28216,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily HFDCGJPN_00875 265072.Mfla_1753 6.8e-76 290.0 Nitrosomonadales greB GO:0006139,GO:0006351,GO:0006352,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141 ko:K04760 ko00000,ko03021 Bacteria 1RAP0@1224,2KMPR@206350,2VQ09@28216,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length HFDCGJPN_00876 265072.Mfla_1754 3.3e-93 348.6 Nitrosomonadales Bacteria 1MYVF@1224,2KKKY@206350,2VHIB@28216,COG4394@1,COG4394@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2331) HFDCGJPN_00877 582744.Msip34_1236 3.3e-95 354.4 Nitrosomonadales efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1MW2J@1224,2KKB2@206350,2VH4A@28216,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase HFDCGJPN_00878 1197719.A464_3853 4.7e-14 84.0 Salmonella Bacteria 1QQWP@1224,1RTM7@1236,29H0M@1,303YA@2,3ZNAD@590 NA|NA|NA HFDCGJPN_00879 573370.DMR_09020 3.3e-24 117.1 Desulfovibrionales phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 1RGUU@1224,2MDNR@213115,2WT2U@28221,42V18@68525,COG2824@1,COG2824@2 NA|NA|NA P PhnA domain HFDCGJPN_00880 987059.RBXJA2T_14606 1.5e-15 90.1 Betaproteobacteria Bacteria 1PAKE@1224,2CEA2@1,2W69J@28216,2ZX6P@2 NA|NA|NA HFDCGJPN_00881 666681.M301_0237 1.7e-102 379.4 Nitrosomonadales thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 R07463 RC01788 ko00000,ko00001,ko01000 Bacteria 1MVIZ@1224,2KKNY@206350,2W7QP@28216,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase HFDCGJPN_00882 582744.Msip34_0208 4.8e-266 923.7 Nitrosomonadales kefB ko:K03455 ko00000 2.A.37 Bacteria 1MV34@1224,2KMER@206350,2VHQQ@28216,COG0475@1,COG0475@2,COG1226@1,COG1226@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family HFDCGJPN_00883 265072.Mfla_0137 4e-128 464.5 Nitrosomonadales kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 iECH74115_1262.ECH74115_4519,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSFxv_1172.SFxv_3550,iYL1228.KPN_03607,iZ_1308.Z4560 Bacteria 1MUXD@1224,2KMBN@206350,2VI24@28216,COG0517@1,COG0517@2,COG0794@1,COG0794@2 NA|NA|NA M Belongs to the SIS family. GutQ KpsF subfamily HFDCGJPN_00884 265072.Mfla_0138 1.8e-66 258.8 Nitrosomonadales kdsC 3.1.3.45 ko:K03270,ko:K11719 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 1.B.42.1 Bacteria 1RH85@1224,2KMW1@206350,2VRQX@28216,COG1778@1,COG1778@2 NA|NA|NA S TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family HFDCGJPN_00885 666681.M301_0233 3e-60 238.4 Nitrosomonadales lptC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 ko:K02040,ko:K11719 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 1.B.42.1,3.A.1.7 iB21_1397.B21_03015,iECBD_1354.ECBD_0543,iECB_1328.ECB_03064,iECD_1391.ECD_03064 Bacteria 1R5UK@1224,2KMR4@206350,2VU37@28216,COG3117@1,COG3117@2 NA|NA|NA S Lipopolysaccharide-assembly, LptC-related HFDCGJPN_00886 1236959.BAMT01000006_gene330 2.8e-67 261.5 Nitrosomonadales lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 ko:K09774 ko00000,ko02000 1.B.42.1 iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 Bacteria 1N776@1224,2KMKV@206350,2VSI4@28216,COG1934@1,COG1934@2 NA|NA|NA S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane HFDCGJPN_00887 582744.Msip34_0203 1.2e-110 406.0 Nitrosomonadales lptB ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 1MU8M@1224,2KM1F@206350,2VH29@28216,COG1137@1,COG1137@2 NA|NA|NA S PFAM ABC transporter HFDCGJPN_00888 265072.Mfla_0142 7.5e-208 729.9 Nitrosomonadales rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 1MW4V@1224,2KKHP@206350,2VIEV@28216,COG1508@1,COG1508@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released HFDCGJPN_00889 666681.M301_0229 5.8e-44 183.3 Nitrosomonadales raiA ko:K05808 ko00000,ko03009 Bacteria 1MZHW@1224,2KMX3@206350,2VU5H@28216,COG1544@1,COG1544@2 NA|NA|NA J PFAM sigma 54 modulation protein ribosomal protein S30EA HFDCGJPN_00890 582744.Msip34_0200 3.2e-138 498.0 Nitrosomonadales hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1NNN5@1224,2KKT6@206350,2VJCH@28216,COG1493@1,COG1493@2 NA|NA|NA T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) HFDCGJPN_00891 582744.Msip34_0199 9.9e-112 409.8 Nitrosomonadales rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1MVX6@1224,2KKJ2@206350,2VIH5@28216,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities HFDCGJPN_00892 582744.Msip34_0198 7.6e-57 226.5 Nitrosomonadales manX 2.7.1.191,2.7.1.194 ko:K02793,ko:K02794,ko:K02821 ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060 M00276,M00283,M00550 R02630,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.7.1 Bacteria 1RHH7@1224,2KMX4@206350,2VT9I@28216,COG2893@1,COG2893@2 NA|NA|NA G PFAM PTS system fructose subfamily IIA component HFDCGJPN_00893 265072.Mfla_0147 3.2e-32 144.1 Nitrosomonadales ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02784,ko:K08485,ko:K11189 ko02060,map02060 ko00000,ko00001,ko02000 4.A.2.1,8.A.8.1.1 Bacteria 1N6RM@1224,2KN6U@206350,2VU8W@28216,COG1925@1,COG1925@2 NA|NA|NA G PFAM phosphoryl transfer system HPr HFDCGJPN_00894 582744.Msip34_0196 4.5e-260 903.7 Nitrosomonadales ptsI 2.7.1.202,2.7.3.9 ko:K02768,ko:K08483,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 Bacteria 1MUT8@1224,2KKUE@206350,2VH9N@28216,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) HFDCGJPN_00895 582744.Msip34_0195 8.1e-33 146.4 Nitrosomonadales ko:K09940 ko00000 Bacteria 1N8TC@1224,2KP9A@206350,2WFWV@28216,COG3296@1,COG3296@2 NA|NA|NA S Domain of unknown function (DUF4870) HFDCGJPN_00896 582744.Msip34_0194 0.0 1131.7 Nitrosomonadales prlC 3.4.24.70 ko:K01414 ko00000,ko01000,ko01002 Bacteria 1MU1K@1224,2KMAM@206350,2VHPQ@28216,COG0339@1,COG0339@2 NA|NA|NA E PFAM peptidase M3A and M3B thimet oligopeptidase F HFDCGJPN_00897 582744.Msip34_0193 4e-40 171.4 Betaproteobacteria Bacteria 1N7X3@1224,2VVPB@28216,COG0695@1,COG0695@2 NA|NA|NA O Pfam Glutaredoxin HFDCGJPN_00898 338969.Rfer_3192 3.4e-21 107.8 Comamonadaceae Bacteria 1MU2C@1224,2VH3V@28216,4A9PA@80864,COG5001@1,COG5001@2 NA|NA|NA T Diguanylate cyclase HFDCGJPN_00899 582744.Msip34_0017 5e-228 797.3 Nitrosomonadales acoR ko:K21405 ko00000,ko03000 Bacteria 1NRG5@1224,2KKV7@206350,2VICI@28216,COG3284@1,COG3284@2 NA|NA|NA KQ GAF domain HFDCGJPN_00903 582744.Msip34_0874 3.7e-224 783.9 Nitrosomonadales alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K00814,ko:K14260 ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00171 R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0337c Bacteria 1MW0Z@1224,2KM2W@206350,2VH4Z@28216,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II HFDCGJPN_00904 582744.Msip34_0873 1.1e-38 166.0 Nitrosomonadales MA20_41450 Bacteria 1N083@1224,2KN4D@206350,2VUF2@28216,COG3737@1,COG3737@2 NA|NA|NA S Protein of unknown function (DUF498/DUF598) HFDCGJPN_00905 1101195.Meth11DRAFT_0933 1.3e-200 705.7 Nitrosomonadales fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Bacteria 1MU1X@1224,2KKN1@206350,2VIWC@28216,COG0304@1,COG0304@2 NA|NA|NA IQ Belongs to the beta-ketoacyl-ACP synthases family HFDCGJPN_00906 1101195.Meth11DRAFT_0932 1.2e-88 332.4 Nitrosomonadales fabA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090 Bacteria 1MWV8@1224,2KM1Q@206350,2VQ71@28216,COG0764@1,COG0764@2 NA|NA|NA I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length HFDCGJPN_00907 1502770.JQMG01000001_gene1655 8.8e-163 579.7 Nitrosomonadales Bacteria 1MUCP@1224,2KM2B@206350,2VN99@28216,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase associated with various cellular activities, AAA_3 HFDCGJPN_00908 1165096.ARWF01000001_gene671 6.4e-114 417.2 Nitrosomonadales mxaS Bacteria 1R69F@1224,2KMFM@206350,2VSZ0@28216,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 HFDCGJPN_00911 1236959.BAMT01000005_gene206 7.2e-91 340.5 Nitrosomonadales ypjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1R3YD@1224,2KKB5@206350,2VK0H@28216,COG4137@1,COG4137@2 NA|NA|NA S PFAM Cytochrome C assembly protein HFDCGJPN_00912 582744.Msip34_2227 7.5e-92 343.6 Nitrosomonadales YPO1315 Bacteria 1RA1A@1224,2KKU6@206350,2VMGV@28216,COG0560@1,COG0560@2 NA|NA|NA E TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 HFDCGJPN_00913 582744.Msip34_2228 8.2e-64 250.4 Nitrosomonadales Bacteria 1RDHR@1224,2KNEN@206350,2VRKF@28216,COG3235@1,COG3235@2 NA|NA|NA S Cobalt uptake substrate-specific transmembrane region HFDCGJPN_00914 666681.M301_2348 1.6e-83 316.2 Nitrosomonadales yedA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1MXX1@1224,2KMIX@206350,2VPGS@28216,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family HFDCGJPN_00915 179408.Osc7112_4200 3.4e-61 241.9 Oscillatoriales Bacteria 1G4QP@1117,1HB8I@1150,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain HFDCGJPN_00916 582744.Msip34_2229 1.9e-262 911.4 Nitrosomonadales leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS10690,iYO844.BSU28280 Bacteria 1MUNQ@1224,2KKGK@206350,2VI4G@28216,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) HFDCGJPN_00917 582744.Msip34_2230 1.2e-122 446.0 Nitrosomonadales pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWD9@1224,2KKHZ@206350,2VIME@28216,COG1183@1,COG1183@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family HFDCGJPN_00918 582744.Msip34_1233 0.0 1142.1 Nitrosomonadales ko:K02659,ko:K03408 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035,ko02044 Bacteria 1QVCF@1224,2KKVY@206350,2VK5W@28216,COG0835@1,COG0835@2 NA|NA|NA NT Two component signalling adaptor domain HFDCGJPN_00919 582744.Msip34_2231 2.9e-188 664.5 Nitrosomonadales tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 Bacteria 1MUCA@1224,2KKC8@206350,2VIRX@28216,COG0343@1,COG0343@2 NA|NA|NA J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) HFDCGJPN_00920 582744.Msip34_2232 1.8e-34 151.8 Nitrosomonadales yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1MZT2@1224,2KN55@206350,2VU6T@28216,COG1862@1,COG1862@2 NA|NA|NA U TIGRFAM preprotein translocase, YajC subunit HFDCGJPN_00921 582744.Msip34_2233 4.9e-273 946.8 Nitrosomonadales secD ko:K03072 ko03060,ko03070,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1MV5U@1224,2KKD5@206350,2VHKD@28216,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA HFDCGJPN_00922 265072.Mfla_0511 1.4e-127 462.6 Nitrosomonadales secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 1MU74@1224,2KKRN@206350,2VHZG@28216,COG0341@1,COG0341@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA HFDCGJPN_00923 582744.Msip34_2235 1.5e-166 592.4 Nitrosomonadales yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 1NZ99@1224,2KKES@206350,2WGFR@28216,COG4536@1,COG4536@2 NA|NA|NA P Transporter associated domain HFDCGJPN_00924 265072.Mfla_0509 7.7e-38 162.9 Nitrosomonadales clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 1MZU8@1224,2KN4C@206350,2VSCU@28216,COG2127@1,COG2127@2 NA|NA|NA S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation HFDCGJPN_00925 582744.Msip34_2331 1.3e-48 199.5 Nitrosomonadales mobB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 ko:K02379,ko:K03750,ko:K03752,ko:K03753,ko:K13818 ko00790,ko01100,map00790,map01100 R09735,R11581 RC03462 ko00000,ko00001,ko01000 iB21_1397.B21_03691,iBWG_1329.BWG_3527,iECBD_1354.ECBD_4174,iECDH1ME8569_1439.ECDH1ME8569_3728,iEcDH1_1363.EcDH1_4130,iJO1366.b3856,iSbBS512_1146.SbBS512_E4328,iY75_1357.Y75_RS17805 Bacteria 1RD3Q@1224,2KN23@206350,2VSIP@28216,COG1763@1,COG1763@2 NA|NA|NA H Molybdopterin guanine dinucleotide synthesis protein B HFDCGJPN_00926 666681.M301_2451 1.3e-57 229.6 Nitrosomonadales mobA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.10.1.1,2.7.7.77 ko:K03750,ko:K03752,ko:K13818 ko00790,ko01100,map00790,map01100 R09735,R11581 RC03462 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801 Bacteria 1RH3M@1224,2KMUA@206350,2VQR2@28216,COG0746@1,COG0746@2 NA|NA|NA H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor HFDCGJPN_00927 666681.M301_2450 2.8e-153 548.1 Nitrosomonadales moaA 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394 RC03420 ko00000,ko00001,ko01000 Bacteria 1MW3W@1224,2KM1Z@206350,2VHW4@28216,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate HFDCGJPN_00928 1502770.JQMG01000001_gene500 1.5e-129 469.9 Nitrosomonadales Bacteria 1MVMG@1224,2KKJQ@206350,2VRIT@28216,COG0457@1,COG0457@2 NA|NA|NA S Putative 2OG-Fe(II) oxygenase HFDCGJPN_00929 582744.Msip34_2323 6.7e-213 746.9 Nitrosomonadales Bacteria 1PUE3@1224,2KMGR@206350,2VHPU@28216,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family HFDCGJPN_00930 1122236.KB905146_gene1948 2.3e-30 137.5 Nitrosomonadales rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ69@1224,2KP7H@206350,2VW5V@28216,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 HFDCGJPN_00931 582744.Msip34_2321 2.3e-229 801.2 Nitrosomonadales rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 1MUCF@1224,2KM7K@206350,2VJ2E@28216,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template HFDCGJPN_00932 1236959.BAMT01000002_gene2100 6.2e-54 216.5 Nitrosomonadales trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291 Bacteria 1MZBB@1224,2KMW7@206350,2VSHX@28216,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family HFDCGJPN_00933 582744.Msip34_2319 1.3e-128 466.5 Nitrosomonadales Bacteria 1PDZY@1224,2KNN2@206350,2VM72@28216,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_00934 582744.Msip34_2318 1e-106 394.0 Nitrosomonadales Bacteria 1PD07@1224,2C2C7@1,2KM9R@206350,2VSM7@28216,2Z85G@2 NA|NA|NA HFDCGJPN_00935 1132855.KB913035_gene611 1.1e-49 203.0 Nitrosomonadales resA ko:K02199 ko00000,ko03110 Bacteria 1N4HY@1224,2KN5X@206350,2VSKM@28216,COG0526@1,COG0526@2 NA|NA|NA CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_00936 582744.Msip34_2315 2e-43 181.4 Nitrosomonadales Bacteria 1N7JM@1224,2KMZD@206350,2VW2N@28216,COG0454@1,COG0456@2 NA|NA|NA K Protein of unknown function (DUF3579) HFDCGJPN_00937 265072.Mfla_2285 1.2e-60 239.6 Nitrosomonadales Bacteria 1MUZ2@1224,2KMN0@206350,2VQIS@28216,COG2823@1,COG2823@2 NA|NA|NA S BON domain HFDCGJPN_00938 582744.Msip34_2313 2.6e-74 285.0 Nitrosomonadales gmhA GO:0003674,GO:0005488,GO:0005515,GO:0006275,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0042802,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0065007,GO:0080090,GO:0090329,GO:2000105,GO:2000112 2.7.1.167,2.7.1.33,2.7.7.70,5.3.1.28 ko:K03271,ko:K03272,ko:K03525,ko:K12961 ko00540,ko00770,ko01100,map00540,map00770,map01100 M00064,M00120 R02971,R03018,R04391,R05644,R05645,R05646,R09768,R09769 RC00002,RC00017,RC00078,RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 Bacteria 1NJ8X@1224,2KN0V@206350,2VN12@28216,COG0279@1,COG0279@2 NA|NA|NA G SIS domain HFDCGJPN_00939 666681.M301_2436 1.4e-32 145.6 Nitrosomonadales yraN ko:K07460 ko00000 Bacteria 1N6VN@1224,2KN5R@206350,2VU20@28216,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family HFDCGJPN_00940 582744.Msip34_2311 1.2e-137 496.9 Nitrosomonadales lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 ko:K03466,ko:K07121 ko00000,ko03036 3.A.12 Bacteria 1MUHR@1224,2KMUT@206350,2VSUT@28216,COG3107@1,COG3107@2 NA|NA|NA M LppC putative lipoprotein HFDCGJPN_00941 582744.Msip34_2310 1.7e-108 399.1 Nitrosomonadales rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1MU0E@1224,2KKNX@206350,2VHI1@28216,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA HFDCGJPN_00942 666681.M301_2433 4.7e-156 557.4 Nitrosomonadales pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUYP@1224,2KKH8@206350,2VH6F@28216,COG0418@1,COG0418@2 NA|NA|NA F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate HFDCGJPN_00943 1123368.AUIS01000031_gene1431 8.7e-143 513.5 Gammaproteobacteria spt 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MWHJ@1224,1RMNR@1236,COG0075@1,COG0075@2 NA|NA|NA E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase HFDCGJPN_00945 582744.Msip34_0451 2.7e-68 264.6 Nitrosomonadales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1RHCG@1224,2KMKN@206350,2VRGP@28216,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family HFDCGJPN_00946 265072.Mfla_2277 1.3e-131 476.1 Nitrosomonadales rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1MUT4@1224,2KM8S@206350,2VIYT@28216,COG0275@1,COG0275@2 NA|NA|NA M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA HFDCGJPN_00947 582744.Msip34_0453 3.5e-31 140.6 Nitrosomonadales ftsL GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 ko:K03586 ko00000,ko03036 Bacteria 1N6WK@1224,2KN6B@206350,2VW1W@28216,COG3116@1,COG3116@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic HFDCGJPN_00948 582744.Msip34_0454 3.2e-274 950.7 Nitrosomonadales ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1MUNY@1224,2KM24@206350,2VIZM@28216,COG0768@1,COG0768@2 NA|NA|NA M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum HFDCGJPN_00949 582744.Msip34_0455 1.7e-167 595.9 Nitrosomonadales murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.4.16.4,6.3.2.10,6.3.2.13 ko:K01928,ko:K03587,ko:K15792 ko00300,ko00550,ko01501,map00300,map00550,map01501 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Bacteria 1MU6P@1224,2KMDD@206350,2WGFS@28216,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan HFDCGJPN_00950 1236959.BAMT01000002_gene2117 1.8e-155 555.8 Nitrosomonadales murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Bacteria 1QTSF@1224,2KMCV@206350,2VH2H@28216,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein HFDCGJPN_00951 1132855.KB913035_gene628 1.2e-176 625.9 Nitrosomonadales mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1MUTK@1224,2KME5@206350,2VHAP@28216,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan HFDCGJPN_00952 583345.Mmol_2006 1.3e-172 612.8 Nitrosomonadales murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Bacteria 1MVYD@1224,2KM82@206350,2VHJ1@28216,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) HFDCGJPN_00953 582744.Msip34_0459 2.5e-185 654.8 Nitrosomonadales ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 1MVDB@1224,2KM9S@206350,2VI5Q@28216,COG0772@1,COG0772@2 NA|NA|NA M Peptidoglycan polymerase that is essential for cell division HFDCGJPN_00954 666681.M301_2422 1.1e-134 486.5 Nitrosomonadales murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1MVIB@1224,2KM6Q@206350,2VH32@28216,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) HFDCGJPN_00955 582744.Msip34_0461 1.5e-226 792.0 Nitrosomonadales murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.45,6.3.2.8 ko:K01924,ko:K02558 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iECP_1309.ECP_0093,iJN678.murC Bacteria 1MV68@1224,2KMBW@206350,2VIKZ@28216,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family HFDCGJPN_00956 1165096.ARWF01000001_gene672 4e-53 214.9 Nitrosomonadales ko:K16256 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1N4P1@1224,2DKVR@1,2KP3S@206350,2W37P@28216,30HS7@2 NA|NA|NA HFDCGJPN_00957 1165096.ARWF01000001_gene673 5.2e-136 490.7 Nitrosomonadales ko:K07114,ko:K16257 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1PRHK@1224,2KKMS@206350,2VS8H@28216,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A HFDCGJPN_00958 1101195.Meth11DRAFT_0927 4e-61 241.1 Nitrosomonadales ko:K16258 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1N2K3@1224,2CEMN@1,2KMTM@206350,2VU8M@28216,32S03@2 NA|NA|NA HFDCGJPN_00959 1101195.Meth11DRAFT_0926 4.4e-130 471.1 Nitrosomonadales ko:K16259 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1MX8R@1224,2KMFJ@206350,2VPW9@28216,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain HFDCGJPN_00960 261292.Nit79A3_1290 7.1e-09 67.0 Nitrosomonadales ko:K19168 ko00000,ko02048 Bacteria 1QVBF@1224,2DTQ5@1,2WGXY@28216,33M9A@2,373GX@32003 NA|NA|NA HFDCGJPN_00961 265072.Mfla_1904 1.4e-107 396.4 Nitrosomonadales ygfZ ko:K06980,ko:K22073 ko00000,ko01000,ko03016,ko03029 Bacteria 1N852@1224,2KKIN@206350,2VK2D@28216,COG0354@1,COG0354@2 NA|NA|NA S Belongs to the GcvT family HFDCGJPN_00963 1198452.Jab_1c25620 1.8e-80 305.8 Oxalobacteraceae ko:K08309 ko00000,ko01000,ko01011 GH23 Bacteria 1R577@1224,2VRNQ@28216,4773C@75682,COG4700@1,COG4700@2 NA|NA|NA S protein conserved in bacteria containing a divergent form of TPR repeats HFDCGJPN_00964 582744.Msip34_1097 1.4e-171 609.0 Nitrosomonadales mrp ko:K03593 ko00000,ko03029,ko03036 Bacteria 1MU7R@1224,2KKRQ@206350,2VIMV@28216,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP HFDCGJPN_00965 1101195.Meth11DRAFT_0948 2.8e-91 341.7 Nitrosomonadales pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057,ko:K02003 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008,M00258 R02035 RC00537 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 1R5K6@1224,2KKG0@206350,2VRZM@28216,COG0363@1,COG0363@2 NA|NA|NA G PFAM glucosamine galactosamine-6-phosphate isomerase HFDCGJPN_00966 582744.Msip34_1094 1.3e-131 476.1 Nitrosomonadales gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1QU14@1224,2KKYK@206350,2WH34@28216,COG1023@1,COG1023@2 NA|NA|NA G TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating) HFDCGJPN_00967 1502770.JQMG01000001_gene1352 2.2e-142 511.9 Nitrosomonadales pmbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 ko:K03592 ko00000,ko01002 Bacteria 1MUVW@1224,2KKFE@206350,2VHJ4@28216,COG0312@1,COG0312@2 NA|NA|NA S PFAM peptidase U62 modulator of DNA gyrase HFDCGJPN_00968 1121004.ATVC01000052_gene13 1.4e-146 526.6 Betaproteobacteria wxcD Bacteria 1NPA5@1224,2W19T@28216,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 HFDCGJPN_00969 582744.Msip34_2180 3.2e-98 364.8 Nitrosomonadales vacJ GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0015711,GO:0015748,GO:0015914,GO:0016043,GO:0033036,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009,GO:0120010 ko:K04754 ko00000 Bacteria 1MVX0@1224,2KKP8@206350,2VQ97@28216,COG2853@1,COG2853@2 NA|NA|NA M MlaA lipoprotein HFDCGJPN_00970 1132855.KB913035_gene472 1.2e-199 702.6 Nitrosomonadales chrA ko:K07240 ko00000,ko02000 2.A.51.1 Bacteria 1MUBW@1224,2KM71@206350,2VHPW@28216,COG2059@1,COG2059@2 NA|NA|NA P TIGRFAM chromate transporter, chromate ion transporter (CHR) family HFDCGJPN_00971 582744.Msip34_2176 1.7e-178 632.1 Nitrosomonadales phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 1MV9Y@1224,2KKBP@206350,2VITS@28216,COG0415@1,COG0415@2 NA|NA|NA L PFAM DNA photolyase FAD-binding HFDCGJPN_00972 326442.PSHAa1036 1.5e-27 129.4 Gammaproteobacteria Bacteria 1R8VC@1224,1S5UD@1236,2C3WA@1,2Z8P1@2 NA|NA|NA HFDCGJPN_00974 261292.Nit79A3_1503 2.5e-50 204.9 Betaproteobacteria soxR Bacteria 1RGW6@1224,2VRHE@28216,COG0789@1,COG0789@2 NA|NA|NA K regulatory protein, MerR HFDCGJPN_00975 1005048.CFU_0019 7.2e-78 297.0 Oxalobacteraceae tpm 2.1.1.67 ko:K00569 ko00983,map00983 R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 Bacteria 1RAE4@1224,2VTM1@28216,477P4@75682,COG0500@1,COG0500@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family HFDCGJPN_00976 595537.Varpa_2217 2e-14 86.7 Proteobacteria Bacteria 1P7P0@1224,291DY@1,2ZP0S@2 NA|NA|NA HFDCGJPN_00977 1236959.BAMT01000008_gene2490 3.6e-37 161.8 Betaproteobacteria Bacteria 1PATY@1224,292J1@1,2W6IF@28216,2ZQ32@2 NA|NA|NA HFDCGJPN_00978 1218352.B597_002160 3.6e-47 194.5 Gammaproteobacteria Bacteria 1MZEJ@1224,1SY96@1236,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein HFDCGJPN_00979 1123242.JH636434_gene3507 1.4e-39 169.1 Planctomycetes Bacteria 2J0Y8@203682,COG5562@1,COG5562@2 NA|NA|NA S phage envelope protein HFDCGJPN_00980 640081.Dsui_0579 7.6e-48 196.8 Rhodocyclales VV2066 ko:K07088 ko00000 Bacteria 1P2SH@1224,2KU7D@206389,2VNH9@28216,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein HFDCGJPN_00982 1502770.JQMG01000001_gene1573 3.1e-96 358.2 Nitrosomonadales ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029,ko:K22132 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000,ko03016 Bacteria 1MWXR@1224,2KMCE@206350,2VJPP@28216,COG1179@1,COG1179@2 NA|NA|NA H PFAM UBA THIF-type NAD FAD binding protein HFDCGJPN_00983 582744.Msip34_1775 7.6e-51 207.6 Nitrosomonadales Bacteria 1QCSR@1224,2B3ND@1,2KNX9@206350,2W84G@28216,31WBT@2 NA|NA|NA HFDCGJPN_00984 582744.Msip34_1776 1.1e-41 176.0 Nitrosomonadales acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1MZBF@1224,2KMWX@206350,2VT0P@28216,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein HFDCGJPN_00985 582744.Msip34_1777 5.4e-106 390.6 Nitrosomonadales pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 iAF1260.b2564,iAF987.Gmet_1885,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 Bacteria 1MU9W@1224,2KM6J@206350,2VHY7@28216,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate HFDCGJPN_00986 582744.Msip34_1778 2.7e-97 361.7 Nitrosomonadales recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 ko:K03474,ko:K03584 ko00750,ko01100,ko03440,map00750,map01100,map03440 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1RHIC@1224,2KM7I@206350,2VJUC@28216,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination HFDCGJPN_00987 265072.Mfla_0864 1.2e-139 502.7 Nitrosomonadales era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 ko:K03595 ko00000,ko03009,ko03029 Bacteria 1MUKT@1224,2KM1D@206350,2VHYP@28216,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism HFDCGJPN_00988 582744.Msip34_1780 1.1e-81 309.7 Nitrosomonadales rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1MUQ6@1224,2KM33@206350,2VI4M@28216,COG0571@1,COG0571@2 NA|NA|NA K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism HFDCGJPN_00989 265072.Mfla_0862 5e-24 117.5 Nitrosomonadales Bacteria 1N71K@1224,2KN83@206350,2W80S@28216,COG4969@1,COG4969@2 NA|NA|NA NU Domain of unknown function (DUF4845) HFDCGJPN_00990 582744.Msip34_1782 3.8e-115 421.0 Nitrosomonadales lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1MXUF@1224,2KKBB@206350,2VJ9D@28216,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family HFDCGJPN_00991 582744.Msip34_1783 3.3e-256 890.6 Nitrosomonadales lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1MVZA@1224,2KM0F@206350,2VHM5@28216,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner HFDCGJPN_00992 582744.Msip34_1600 2.5e-207 728.0 Nitrosomonadales ydeP 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 R00519 RC02796 ko00000,ko00001,ko01000 Bacteria 1MU6B@1224,2KKI2@206350,2VKT8@28216,COG0243@1,COG0243@2 NA|NA|NA C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family HFDCGJPN_00994 582744.Msip34_1737 0.0 1128.6 Nitrosomonadales typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1MV5Q@1224,2KKVX@206350,2VH2W@28216,COG1217@1,COG1217@2 NA|NA|NA T Elongation factor Tu domain 2 HFDCGJPN_00995 1132855.KB913035_gene261 9.9e-124 449.5 Nitrosomonadales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 1MW88@1224,2KKN6@206350,2VJGH@28216,COG0412@1,COG0412@2 NA|NA|NA Q PFAM Dienelactone hydrolase HFDCGJPN_00996 1112274.KI911560_gene1110 1.3e-140 506.5 Nitrosomonadales gabR_1 ko:K00375 ko00000,ko03000 Bacteria 1MV6F@1224,2KM87@206350,2VHE6@28216,COG1167@1,COG1167@2 NA|NA|NA EK helix_turn_helix gluconate operon transcriptional repressor HFDCGJPN_00997 1163617.SCD_n01943 1.1e-135 489.6 Betaproteobacteria hda Bacteria 1MU7P@1224,2VIK8@28216,COG0123@1,COG0123@2 NA|NA|NA BQ histone deacetylase HFDCGJPN_00998 1163617.SCD_n01944 0.0 1354.3 Betaproteobacteria yfiQ 6.2.1.13 ko:K01905,ko:K09181,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 Bacteria 1MW98@1224,2VI9R@28216,COG0045@1,COG0045@2,COG0454@1,COG0456@2,COG1042@1,COG1042@2 NA|NA|NA C CoA-binding domain protein HFDCGJPN_00999 1101195.Meth11DRAFT_0011 1.2e-77 296.2 Nitrosomonadales ko:K07006 ko00000 Bacteria 1NBWC@1224,2KNWX@206350,2VKQ8@28216,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase HFDCGJPN_01000 1236959.BAMT01000008_gene2508 9.8e-35 152.9 Nitrosomonadales Bacteria 1PJNE@1224,2KNDG@206350,2W652@28216,COG3370@1,COG3370@2 NA|NA|NA S DsrE/DsrF-like family HFDCGJPN_01001 102125.Xen7305DRAFT_00019930 1.2e-28 133.3 Pleurocapsales Bacteria 1G76B@1117,3VJUR@52604,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family HFDCGJPN_01004 582744.Msip34_2194 2.7e-206 724.5 Nitrosomonadales lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW3H@1224,2KMF2@206350,2VINP@28216,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family HFDCGJPN_01005 582744.Msip34_2193 4.4e-105 387.5 Nitrosomonadales alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 Bacteria 1MU9A@1224,2KMGG@206350,2VH6Z@28216,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain HFDCGJPN_01006 265072.Mfla_2747 1.1e-68 266.2 Nitrosomonadales atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 Bacteria 1MVRH@1224,2KM92@206350,2VSJV@28216,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation HFDCGJPN_01007 582744.Msip34_2819 6.7e-25 120.6 Nitrosomonadales atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 Bacteria 1RHZ0@1224,2KMJT@206350,2VRMS@28216,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) HFDCGJPN_01008 1236959.BAMT01000007_gene2614 4.5e-37 160.2 Nitrosomonadales atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1N1NA@1224,2KN1J@206350,2VTY0@28216,32S3K@2,COG0636@1 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation HFDCGJPN_01009 1122236.KB905145_gene2480 1.2e-127 462.6 Nitrosomonadales atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1MV87@1224,2KKB3@206350,2VHR5@28216,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane HFDCGJPN_01010 666681.M301_2789 1.4e-15 89.4 Betaproteobacteria atpI GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02116 ko00000,ko00194 3.A.2.1 iSSON_1240.SSON_3880 Bacteria 1R3CS@1224,2WIGV@28216,COG3312@1,COG3312@2 NA|NA|NA C ATP synthase I chain HFDCGJPN_01011 582744.Msip34_2823 4.7e-101 374.4 Nitrosomonadales parB ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1MW2E@1224,2KM1A@206350,2VIG0@28216,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family HFDCGJPN_01012 265072.Mfla_2753 1.8e-110 405.6 Nitrosomonadales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 1MV43@1224,2KM9W@206350,2VHNK@28216,COG1192@1,COG1192@2 NA|NA|NA D PFAM Cobyrinic acid a,c-diamide synthase HFDCGJPN_01013 1236959.BAMT01000007_gene2608 2.3e-68 265.4 Nitrosomonadales rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1MY0K@1224,2KMP1@206350,2VR3B@28216,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA HFDCGJPN_01014 582744.Msip34_2826 0.0 1077.4 Nitrosomonadales gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1MU6F@1224,2KMCJ@206350,2VIGG@28216,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 HFDCGJPN_01015 1502770.JQMG01000001_gene24 7.1e-42 176.8 Betaproteobacteria shp Bacteria 1N1Z3@1224,2VU18@28216,COG2010@1,COG2010@2 NA|NA|NA C Domain of unknown function (DUF1924) HFDCGJPN_01016 1122236.KB905145_gene2473 4e-53 214.9 Nitrosomonadales Bacteria 1RIG7@1224,2KNX3@206350,2VQQ0@28216,COG3658@1,COG3658@2 NA|NA|NA C Prokaryotic cytochrome b561 HFDCGJPN_01017 582744.Msip34_2827 2.3e-187 661.8 Nitrosomonadales mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1MUCQ@1224,2KKTD@206350,2VHCJ@28216,COG0486@1,COG0486@2 NA|NA|NA J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 HFDCGJPN_01018 582744.Msip34_2828 2.4e-203 714.9 Nitrosomonadales yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1MV5M@1224,2KM2S@206350,2VHIA@28216,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins HFDCGJPN_01019 582744.Msip34_0357 2.8e-244 851.3 Nitrosomonadales msbA ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1MUBM@1224,2KKNE@206350,2VHAN@28216,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region HFDCGJPN_01020 1101195.Meth11DRAFT_0032 2.4e-32 146.0 Nitrosomonadales Bacteria 1PJHV@1224,2A8KC@1,2KN4P@206350,2W805@28216,30XNQ@2 NA|NA|NA HFDCGJPN_01021 666681.M301_2682 7.9e-68 263.5 Betaproteobacteria nasT ko:K07183,ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 1MXDV@1224,2VSMR@28216,COG3707@1,COG3707@2 NA|NA|NA K response regulator HFDCGJPN_01022 582744.Msip34_0354 4.9e-219 766.9 Nitrosomonadales nasF ko:K02051,ko:K15576,ko:K15598,ko:K22067 ko00910,ko02010,map00910,map02010 M00188,M00438,M00442 ko00000,ko00001,ko00002,ko02000,ko02022 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17,3.A.1.17.3,3.A.1.17.6 Bacteria 1MWDN@1224,2KKIU@206350,2VIJH@28216,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family HFDCGJPN_01023 582744.Msip34_0353 1.4e-130 472.6 Nitrosomonadales nasE ko:K15577 ko00910,ko02010,map00910,map02010 M00438 ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 Bacteria 1MU6Q@1224,2KKTA@206350,2VH12@28216,COG0600@1,COG0600@2 NA|NA|NA P PFAM binding-protein-dependent transport systems inner membrane component HFDCGJPN_01024 582744.Msip34_0352 5e-129 467.2 Nitrosomonadales nasD 3.6.3.36 ko:K02049,ko:K10831,ko:K11952,ko:K11953,ko:K15578,ko:K15579 ko00910,ko00920,ko02010,map00910,map00920,map02010 M00188,M00321,M00435,M00438 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.16.3,3.A.1.17,3.A.1.17.1,3.A.1.17.4 Bacteria 1MUDV@1224,2KKCJ@206350,2VJXH@28216,COG1116@1,COG1116@2 NA|NA|NA P TIGRFAM nitrate ABC transporter, ATPase subunits C and D HFDCGJPN_01025 666681.M301_2678 1.9e-183 649.0 Nitrosomonadales Bacteria 1MXAM@1224,2C3QV@1,2KKK2@206350,2W7NZ@28216,2Z7YP@2 NA|NA|NA S Alginate export HFDCGJPN_01026 582744.Msip34_0349 3.8e-97 361.3 Nitrosomonadales cobA GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUI0@1224,2KMJ8@206350,2VICS@28216,COG0007@1,COG0007@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases HFDCGJPN_01027 1101195.Meth11DRAFT_0415 0.0 1545.8 Nitrosomonadales nirB 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW58@1224,2KKDA@206350,2VIEA@28216,COG1251@1,COG1251@2 NA|NA|NA C TIGRFAM nitrite reductase NAD(P)H , large subunit HFDCGJPN_01028 666681.M301_2676 7.4e-193 679.9 Nitrosomonadales nasA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02575 ko00910,map00910 M00615 ko00000,ko00001,ko00002,ko02000 2.A.1.8 iYO844.BSU03330 Bacteria 1MU27@1224,2KKB7@206350,2VI6Q@28216,COG2223@1,COG2223@2 NA|NA|NA P PFAM Major Facilitator Superfamily HFDCGJPN_01032 582744.Msip34_0389 9.2e-106 389.8 Nitrosomonadales fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1MU6N@1224,2KKE8@206350,2VK4I@28216,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family HFDCGJPN_01033 1236959.BAMT01000011_gene3207 1.1e-32 146.0 Nitrosomonadales Bacteria 1N98H@1224,2C1YJ@1,2KN7D@206350,2VVT5@28216,32ZXK@2 NA|NA|NA S Protein of unknown function (DUF2782) HFDCGJPN_01034 582744.Msip34_0391 1e-120 439.9 Nitrosomonadales thrB 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUKJ@1224,2KM53@206350,2VH2I@28216,COG2334@1,COG2334@2 NA|NA|NA F Belongs to the pseudomonas-type ThrB family HFDCGJPN_01035 1163617.SCD_n00048 8.7e-59 233.8 Betaproteobacteria Bacteria 1N9UJ@1224,2VNM5@28216,COG5473@1,COG5473@2 NA|NA|NA HFDCGJPN_01036 1502770.JQMG01000001_gene1233 0.0 1189.1 Nitrosomonadales uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU0G@1224,2KKFV@206350,2VH4I@28216,COG0210@1,COG0210@2 NA|NA|NA L UvrD REP helicase HFDCGJPN_01037 1132855.KB913035_gene2410 4.4e-273 946.8 Nitrosomonadales groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1MURR@1224,2KKWW@206350,2VIW1@28216,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions HFDCGJPN_01038 1123392.AQWL01000002_gene1818 8.6e-39 166.0 Hydrogenophilales groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1KRSD@119069,1MZ2X@1224,2VSKJ@28216,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter HFDCGJPN_01039 265072.Mfla_0376 1.4e-26 126.3 Nitrosomonadales Bacteria 1PJJA@1224,2EP1C@1,2KN97@206350,2W810@28216,33GN7@2 NA|NA|NA HFDCGJPN_01041 1101195.Meth11DRAFT_0462 2.2e-176 625.2 Nitrosomonadales bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 iIT341.HP0976,iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Bacteria 1MU2N@1224,2KKMC@206350,2VKJI@28216,COG0161@1,COG0161@2 NA|NA|NA H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family HFDCGJPN_01042 582744.Msip34_0431 9.4e-147 526.9 Nitrosomonadales dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1MW40@1224,2KKBD@206350,2VH20@28216,COG2027@1,COG2027@2 NA|NA|NA M PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C HFDCGJPN_01043 265072.Mfla_0379 2e-61 241.9 Nitrosomonadales fbp 5.2.1.8 ko:K01802,ko:K03772 ko00000,ko01000,ko03110 Bacteria 1RDA1@1224,2KMQT@206350,2VSIG@28216,COG0545@1,COG0545@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase HFDCGJPN_01044 582744.Msip34_0434 3.1e-69 267.7 Nitrosomonadales yhfA ko:K07397 ko00000 Bacteria 1RCZW@1224,2KMKZ@206350,2VR62@28216,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein HFDCGJPN_01045 582744.Msip34_0435 7.2e-54 216.5 Nitrosomonadales Bacteria 1RIR2@1224,2KMVH@206350,2W7ZA@28216,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase HFDCGJPN_01046 1236959.BAMT01000005_gene53 5.5e-28 130.2 Nitrosomonadales Z012_04380 Bacteria 1N8RK@1224,2KN3A@206350,2VUJW@28216,COG4390@1,COG4390@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2322) HFDCGJPN_01047 582744.Msip34_0438 5.3e-78 297.4 Nitrosomonadales coq7 ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 Bacteria 1RAA1@1224,2KMJS@206350,2VQRE@28216,COG2941@1,COG2941@2 NA|NA|NA H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol HFDCGJPN_01048 582744.Msip34_0439 3.6e-207 727.6 Nitrosomonadales ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1MU39@1224,2KKV4@206350,2VJ86@28216,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family HFDCGJPN_01049 582744.Msip34_0440 2.1e-34 151.4 Nitrosomonadales ko:K07401 ko00000 Bacteria 1MZ5V@1224,2KN56@206350,2VUXZ@28216,COG3526@1,COG3526@2 NA|NA|NA O Rdx family HFDCGJPN_01050 582744.Msip34_0442 1.3e-53 216.1 Nitrosomonadales yafL GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 ko:K19303 ko00000,ko01000,ko01002,ko01011 Bacteria 1N0EE@1224,2KMWD@206350,2VSHN@28216,COG0791@1,COG0791@2 NA|NA|NA M PFAM NLP P60 protein HFDCGJPN_01052 582744.Msip34_0444 3.3e-268 930.6 Nitrosomonadales aarF ko:K03688 ko00000 Bacteria 1MU1Z@1224,2KNIT@206350,2VJ9H@28216,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family HFDCGJPN_01053 582744.Msip34_2397 2e-48 199.5 Nitrosomonadales cpoB GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1MUSV@1224,2KMMT@206350,2VIPC@28216,COG1729@1,COG1729@2 NA|NA|NA D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division HFDCGJPN_01054 582744.Msip34_2398 3.8e-56 224.6 Nitrosomonadales pal GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 ko:K03640 ko00000,ko02000 2.C.1.2 Bacteria 1MZTV@1224,2KMV3@206350,2VSP6@28216,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family HFDCGJPN_01055 582744.Msip34_2399 9.5e-130 470.3 Nitrosomonadales tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 1MV09@1224,2KKVW@206350,2VH9R@28216,COG0823@1,COG0823@2 NA|NA|NA U Involved in the TonB-independent uptake of proteins HFDCGJPN_01056 582744.Msip34_2400 1.7e-49 203.0 Nitrosomonadales tolA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0017038,GO:0019058,GO:0019904,GO:0030260,GO:0031224,GO:0031226,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046677,GO:0046678,GO:0046718,GO:0046790,GO:0050896,GO:0051179,GO:0051234,GO:0051301,GO:0051701,GO:0051704,GO:0051716,GO:0051806,GO:0051828,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071944,GO:0097718,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 ko:K03646 ko00000,ko02000 2.C.1.2 Bacteria 1RKZU@1224,2KMSA@206350,2WGP5@28216,COG3064@1,COG3064@2 NA|NA|NA M TIGRFAM protein TolA HFDCGJPN_01057 666681.M301_2510 6.3e-48 196.8 Nitrosomonadales tolR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03560 ko00000,ko02000 1.A.30.2.2 Bacteria 1RGWR@1224,2KMYC@206350,2VT20@28216,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR HFDCGJPN_01058 1236959.BAMT01000002_gene2030 8.7e-98 363.2 Nitrosomonadales tolQ ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.2 Bacteria 1NCWW@1224,2KM84@206350,2VJPW@28216,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel HFDCGJPN_01059 265072.Mfla_2343 7.7e-41 173.3 Nitrosomonadales ybgC 3.1.2.23 ko:K01075,ko:K07107 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 R01301 RC00004,RC00174 ko00000,ko00001,ko01000 Bacteria 1MZH6@1224,2KMYI@206350,2VUEV@28216,COG0824@1,COG0824@2 NA|NA|NA S tol-pal system-associated acyl-CoA thioesterase HFDCGJPN_01060 1101195.Meth11DRAFT_2365 1.9e-168 598.6 Nitrosomonadales ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU38@1224,2KKIG@206350,2VH0J@28216,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing HFDCGJPN_01061 582744.Msip34_2405 1.1e-80 306.2 Nitrosomonadales ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWJR@1224,2KM9H@206350,2VJ98@28216,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB HFDCGJPN_01062 666681.M301_2520 1.7e-80 305.4 Nitrosomonadales ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUJI@1224,2KM83@206350,2VQ3U@28216,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group HFDCGJPN_01063 1502770.JQMG01000001_gene531 1.2e-113 416.0 Nitrosomonadales yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1MW3X@1224,2KM7Q@206350,2VIA5@28216,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulator HFDCGJPN_01064 265072.Mfla_2356 5.9e-126 457.2 Nitrosomonadales yijE GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:1901682,GO:1903825,GO:1905039 Bacteria 1NEYM@1224,2KMJ2@206350,2VPAG@28216,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family HFDCGJPN_01065 265072.Mfla_2357 1.3e-31 142.5 Nitrosomonadales Bacteria 1NP1S@1224,2KN47@206350,2WG7T@28216,COG4319@1,COG4319@2 NA|NA|NA S Nuclear transport factor 2 (NTF2) domain HFDCGJPN_01066 582744.Msip34_2410 5.6e-65 253.8 Nitrosomonadales yetL GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K15973 ko00000,ko03000 Bacteria 1N1RV@1224,2KMKD@206350,2VSUW@28216,COG1846@1,COG1846@2 NA|NA|NA K PFAM regulatory protein MarR HFDCGJPN_01067 582744.Msip34_2411 1.7e-46 192.2 Nitrosomonadales Bacteria 1QTTR@1224,2KMWZ@206350,2WGT1@28216,COG2905@1,COG2905@2 NA|NA|NA T PFAM CBS domain containing protein HFDCGJPN_01068 582744.Msip34_2415 2.7e-73 281.2 Nitrosomonadales Bacteria 1RA5G@1224,2KMMP@206350,2W271@28216,COG0432@1,COG0432@2 NA|NA|NA S Uncharacterised protein family UPF0047 HFDCGJPN_01070 582744.Msip34_1036 3.1e-17 94.7 Nitrosomonadales mliC ko:K09914 ko00000 Bacteria 1PJJS@1224,2KNAS@206350,2W81D@28216,COG3895@1,COG3895@2 NA|NA|NA S Periplasmic Protein HFDCGJPN_01072 582744.Msip34_2446 1.4e-135 489.6 Nitrosomonadales clsB ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1MWUW@1224,2KMI5@206350,2VI41@28216,COG1502@1,COG1502@2 NA|NA|NA I phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol HFDCGJPN_01073 265072.Mfla_2380 1.1e-85 323.2 Nitrosomonadales ybhP Bacteria 1MVN7@1224,2KKB8@206350,2VJYW@28216,COG3568@1,COG3568@2 NA|NA|NA L PFAM Endonuclease Exonuclease phosphatase HFDCGJPN_01074 582744.Msip34_2448 1.1e-190 672.5 Nitrosomonadales nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWQU@1224,2KM5Z@206350,2VH6N@28216,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate HFDCGJPN_01075 582744.Msip34_1169 7.3e-14 82.8 Nitrosomonadales Bacteria 1PJKE@1224,2A8NE@1,2KNBS@206350,2W81K@28216,30XQY@2 NA|NA|NA HFDCGJPN_01076 583345.Mmol_1493 6e-86 323.9 Nitrosomonadales Bacteria 1N018@1224,2CDK7@1,2KMTF@206350,2VH8P@28216,2ZAP2@2 NA|NA|NA HFDCGJPN_01077 582744.Msip34_2757 1.1e-32 145.6 Nitrosomonadales hupB ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1MZ5B@1224,2KN3Y@206350,2VU4V@28216,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions HFDCGJPN_01078 760117.JN27_12590 1.6e-22 112.8 Oxalobacteraceae cheW ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1RD1W@1224,2VR41@28216,4745S@75682,COG0835@1,COG0835@2 NA|NA|NA NT Two component signalling adaptor domain HFDCGJPN_01079 1101195.Meth11DRAFT_1500 9.6e-78 296.6 Nitrosomonadales cheZ ko:K03414 ko02030,map02030 ko00000,ko00001,ko02035 Bacteria 1NIV6@1224,2KP71@206350,2VN5G@28216,COG3143@1,COG3143@2 NA|NA|NA NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) HFDCGJPN_01080 666681.M301_0900 1.1e-60 239.2 Nitrosomonadales Bacteria 1RDNP@1224,2KMNI@206350,2VR8X@28216,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_01081 666681.M301_0899 2.5e-160 571.6 Nitrosomonadales cheB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827 2.1.1.80,3.1.1.61,3.5.1.44 ko:K03412,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 1MWCN@1224,2KM43@206350,2VI13@28216,COG2201@1,COG2201@2 NA|NA|NA NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR HFDCGJPN_01082 582744.Msip34_0817 2.5e-96 358.2 Nitrosomonadales cheD 3.1.1.61,3.5.1.44 ko:K03411,ko:K03412 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 Bacteria 1RDDB@1224,2KKB1@206350,2VJ1T@28216,COG1871@1,COG1871@2 NA|NA|NA NT Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis HFDCGJPN_01083 666681.M301_0897 3e-127 461.5 Nitrosomonadales cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 Bacteria 1MU6W@1224,2KM8G@206350,2VKFS@28216,COG1352@1,COG1352@2 NA|NA|NA NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP HFDCGJPN_01084 1101195.Meth11DRAFT_1506 2.9e-279 968.0 Nitrosomonadales ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2KKQK@206350,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA NT PFAM chemotaxis sensory transducer HFDCGJPN_01085 1101195.Meth11DRAFT_1507 9.1e-284 983.0 Nitrosomonadales ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2KKQK@206350,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA NT PFAM chemotaxis sensory transducer HFDCGJPN_01086 666681.M301_1396 5.4e-112 410.6 Nitrosomonadales fixB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006575,GO:0006577,GO:0006579,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009437,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0034641,GO:0036094,GO:0042219,GO:0042413,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:0097164,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.3.8.1 ko:K00248,ko:K03522 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000,ko04147 Bacteria 1MUFI@1224,2KKF9@206350,2VJWA@28216,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein FAD-binding domain HFDCGJPN_01088 666681.M301_1426 1.3e-49 202.2 Nitrosomonadales eutQ ko:K04019,ko:K04030 ko00564,ko01100,map00564,map01100 R00749 RC00370 ko00000,ko00001 Bacteria 1NX4X@1224,2KNWR@206350,2W84D@28216,COG4766@1,COG4766@2 NA|NA|NA E Ethanolamine utilisation protein EutQ HFDCGJPN_01089 1026882.MAMP_00519 2.4e-72 278.9 Gammaproteobacteria ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1R5X6@1224,1S8A3@1236,COG0840@1,COG0840@2 NA|NA|NA NT methyl-accepting chemotaxis protein HFDCGJPN_01090 1165096.ARWF01000001_gene402 8.7e-30 135.6 Nitrosomonadales scoF ko:K03704 ko00000,ko03000 Bacteria 1N6Q5@1224,2KNYH@206350,2WAP9@28216,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain HFDCGJPN_01091 1101195.Meth11DRAFT_1162 4.2e-32 143.7 Nitrosomonadales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1MZFU@1224,2KN2T@206350,2VU4I@28216,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex HFDCGJPN_01093 582744.Msip34_1722 0.0 1248.4 Nitrosomonadales rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1MUS6@1224,2KKCC@206350,2VHBJ@28216,COG0557@1,COG0557@2 NA|NA|NA K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs HFDCGJPN_01094 395494.Galf_1995 6.3e-54 216.9 Nitrosomonadales GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042802,GO:0042803,GO:0046983 3.1.2.29 ko:K18700 ko00000,ko01000 Bacteria 1RKFT@1224,2VV65@28216,44WEX@713636,COG5496@1,COG5496@2 NA|NA|NA S Thioesterase HFDCGJPN_01096 1132855.KB913035_gene1704 3.3e-122 444.5 Betaproteobacteria Bacteria 1N2Y0@1224,2VH72@28216,COG0426@1,COG0426@2 NA|NA|NA C PFAM beta-lactamase domain protein HFDCGJPN_01097 583345.Mmol_0717 2.7e-26 124.4 Betaproteobacteria ccoH ko:K09926 ko00000 Bacteria 1N8D0@1224,2VWBW@28216,COG3198@1,COG3198@2 NA|NA|NA S FixH HFDCGJPN_01098 1132855.KB913035_gene2088 1.2e-202 712.6 Nitrosomonadales ccoG Bacteria 1MVFY@1224,2KKZG@206350,2VHRH@28216,COG0348@1,COG0348@2 NA|NA|NA C TIGRFAM cytochrome c oxidase accessory protein HFDCGJPN_01099 666681.M301_1916 1.1e-135 489.6 Nitrosomonadales ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 iJN746.PP_4253 Bacteria 1MUCW@1224,2KMD1@206350,2VHGS@28216,COG2010@1,COG2010@2 NA|NA|NA C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex HFDCGJPN_01100 666681.M301_1915 6.9e-10 68.9 Nitrosomonadales ccoQ ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1PJSJ@1224,2KP11@206350,2W85S@28216,COG4736@1,COG4736@2 NA|NA|NA O PFAM Cbb3-type cytochrome oxidase component HFDCGJPN_01101 614083.AWQR01000005_gene923 2.5e-99 368.2 Comamonadaceae ccoO 1.9.3.1 ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0145 Bacteria 1MXEY@1224,2VIJ2@28216,4ABQK@80864,COG2993@1,COG2993@2 NA|NA|NA C cytochrome c oxidase, cbb3-type, subunit II HFDCGJPN_01102 666681.M301_1913 2.9e-260 904.0 Nitrosomonadales ccoN GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144 Bacteria 1MU18@1224,2KKTV@206350,2VIWB@28216,COG3278@1,COG3278@2 NA|NA|NA C TIGRFAM cytochrome c oxidase, cbb3-type, subunit I HFDCGJPN_01103 1101195.Meth11DRAFT_1239 3.8e-13 79.7 Nitrosomonadales ccoS Bacteria 1PUR3@1224,2KNBW@206350,2WAW7@28216,COG3197@1,COG3197@2 NA|NA|NA P TIGRFAM cytochrome oxidase maturation protein, cbb3-type HFDCGJPN_01104 1101195.Meth11DRAFT_1238 1.3e-251 875.9 Nitrosomonadales fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1MU08@1224,2KM5C@206350,2VJSM@28216,COG2217@1,COG2217@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC HFDCGJPN_01105 159087.Daro_2825 3.5e-48 199.1 Rhodocyclales 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1R7HC@1224,2KZQ7@206389,2VRXY@28216,COG0745@1,COG0745@2,COG2199@1,COG3290@1,COG3290@2,COG3706@2,COG3829@1,COG3829@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_01106 582744.Msip34_1508 9.4e-67 259.6 Nitrosomonadales ffsA GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 ko:K00672 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03390 RC00197,RC00870,RC02881 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVSD@1224,2KME8@206350,2VJSP@28216,COG2037@1,COG2037@2 NA|NA|NA C Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) HFDCGJPN_01107 582744.Msip34_1509 1.4e-49 203.4 Nitrosomonadales fhcC GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 ko:K00202 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03015,R08060,R11743 RC00197,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUUQ@1224,2KKC9@206350,2VMB1@28216,COG2218@1,COG2218@2 NA|NA|NA C PFAM glutamate synthase alpha subunit domain protein HFDCGJPN_01108 265072.Mfla_1667 3.3e-71 274.6 Nitrosomonadales yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1NFJC@1224,2KMQY@206350,2VWRI@28216,COG1739@1,COG1739@2 NA|NA|NA S Uncharacterized protein family UPF0029 HFDCGJPN_01110 525257.HMPREF0204_14146 9.1e-54 217.2 Chryseobacterium Bacteria 1I0S4@117743,3ZTII@59732,4NGYF@976,COG0500@1,COG2226@2 NA|NA|NA Q Mycolic acid cyclopropane synthetase HFDCGJPN_01111 1165096.ARWF01000001_gene1935 1.6e-105 389.0 Nitrosomonadales gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MU7V@1224,2KKM2@206350,2VHQ1@28216,COG2804@1,COG2804@2 NA|NA|NA NU PFAM type II secretion system HFDCGJPN_01112 580332.Slit_1829 1.3e-18 100.5 Nitrosomonadales Bacteria 1PXFZ@1224,2BGQG@1,2WCW7@28216,32APG@2,44WJ8@713636 NA|NA|NA HFDCGJPN_01113 857087.Metme_2699 2.2e-204 718.4 Methylococcales yhjX ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1QU0F@1224,1T1JZ@1236,1XETP@135618,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily HFDCGJPN_01117 582744.Msip34_2237 6.8e-140 503.4 Nitrosomonadales clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K03694 ko00000,ko03110 Bacteria 1MV8B@1224,2KKYH@206350,2VH1K@28216,COG0542@1,COG0542@2 NA|NA|NA O TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA HFDCGJPN_01118 582744.Msip34_2238 1.4e-58 232.6 Nitrosomonadales GSTO1 2.5.1.18 ko:K00799,ko:K07146 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1RD2G@1224,2KMJY@206350,2VRS9@28216,COG0625@1,COG0625@2 NA|NA|NA O PFAM Glutathione S-transferase HFDCGJPN_01119 582744.Msip34_2239 1.3e-14 85.1 Betaproteobacteria Bacteria 1NCDQ@1224,2DPD6@1,2VWA7@28216,331K2@2 NA|NA|NA S Protein of unknown function (DUF2892) HFDCGJPN_01120 583345.Mmol_1944 1.5e-149 535.8 Nitrosomonadales pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 Bacteria 1MU7C@1224,2KM0T@206350,2VJ6H@28216,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor HFDCGJPN_01121 1165096.ARWF01000001_gene2098 0.0 1323.9 Nitrosomonadales yoaE Bacteria 1NR6J@1224,2KMJA@206350,2VHHZ@28216,COG0243@1,COG0243@2 NA|NA|NA C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family HFDCGJPN_01122 1132855.KB913035_gene857 1.3e-46 192.2 Nitrosomonadales ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 1N32M@1224,2KMXR@206350,2VUEY@28216,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family HFDCGJPN_01123 582744.Msip34_2243 0.0 1689.9 Nitrosomonadales ko:K15726 ko00000,ko02000 2.A.6.1.2 Bacteria 1NUIV@1224,2KMJ1@206350,2VHCZ@28216,COG3696@1,COG3696@2 NA|NA|NA P AcrB/AcrD/AcrF family HFDCGJPN_01124 1132855.KB913035_gene857 1.5e-47 195.3 Nitrosomonadales ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 1N32M@1224,2KMXR@206350,2VUEY@28216,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family HFDCGJPN_01125 582744.Msip34_2245 0.0 1590.9 Nitrosomonadales ko:K15726 ko00000,ko02000 2.A.6.1.2 Bacteria 1NUIV@1224,2KMG8@206350,2VHCZ@28216,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family HFDCGJPN_01126 640081.Dsui_1207 3.3e-66 260.0 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KW9H@206389,2VHFJ@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_01128 395493.BegalDRAFT_0395 3.1e-124 452.6 Gammaproteobacteria 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDES@1224,1S0RQ@1236,COG2114@1,COG2114@2,COG5000@1,COG5000@2 NA|NA|NA T Adenylyl- / guanylyl cyclase, catalytic domain HFDCGJPN_01129 666681.M301_2721 3.2e-64 251.5 Nitrosomonadales ribA 3.5.4.25,4.1.99.12 ko:K01497,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWZR@1224,2KMKQ@206350,2VRA8@28216,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate HFDCGJPN_01130 1454004.AW11_03578 1.7e-55 223.4 Proteobacteria lytM Bacteria 1N19D@1224,COG0739@1,COG0739@2 NA|NA|NA M peptidase HFDCGJPN_01131 1122236.KB905146_gene1967 0.0 1155.6 Nitrosomonadales Bacteria 1MUQX@1224,2KMEC@206350,2VHVH@28216,COG4993@1,COG4993@2 NA|NA|NA G TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family HFDCGJPN_01132 582744.Msip34_2349 1.9e-119 435.6 Nitrosomonadales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1MWW8@1224,2KM4G@206350,2VIEF@28216,COG0596@1,COG0596@2 NA|NA|NA E Belongs to the peptidase S33 family HFDCGJPN_01133 582744.Msip34_2350 2.6e-167 595.1 Nitrosomonadales ko:K03455,ko:K07058 ko00000 2.A.37 Bacteria 1PWBZ@1224,2KKMG@206350,2VY5Z@28216,COG0664@1,COG0664@2,COG1295@1,COG1295@2 NA|NA|NA T Virulence factor BrkB HFDCGJPN_01135 582744.Msip34_2380 7.6e-309 1065.8 Nitrosomonadales rpoD ko:K03086 ko00000,ko03021 Bacteria 1MVNJ@1224,2KM37@206350,2VH74@28216,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth HFDCGJPN_01136 582744.Msip34_2381 5.8e-255 886.7 Nitrosomonadales dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1MUHC@1224,2KMBJ@206350,2VHI9@28216,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication HFDCGJPN_01137 582744.Msip34_2382 2.7e-55 221.5 Nitrosomonadales yqeY ko:K09117 ko00000 Bacteria 1RGZS@1224,2KMWB@206350,2VR35@28216,COG1610@1,COG1610@2 NA|NA|NA S Yqey-like protein HFDCGJPN_01138 1236959.BAMT01000002_gene2050 7.7e-29 132.5 Nitrosomonadales rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZCC@1224,2KN41@206350,2VTZ4@28216,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family HFDCGJPN_01139 582744.Msip34_2384 3.9e-158 564.3 Nitrosomonadales tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1MU6S@1224,2KKKS@206350,2VHDR@28216,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction HFDCGJPN_01140 582744.Msip34_2385 1.5e-77 295.8 Nitrosomonadales plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,2.7.9.2,3.5.1.104 ko:K01007,ko:K03977,ko:K08591,ko:K22278 ko00561,ko00564,ko00620,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,map00561,map00564,map00620,map00680,map00720,map01100,map01110,map01120,map01200 M00089,M00173,M00374 R00199,R00851,R09380 RC00002,RC00004,RC00015,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko03009 Bacteria 1RD4Z@1224,2KMN9@206350,2VQ10@28216,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP HFDCGJPN_01141 582744.Msip34_2386 8.6e-49 199.5 Nitrosomonadales folB 1.13.11.81,3.1.3.18,4.1.2.25,5.1.99.8 ko:K01091,ko:K01633 ko00630,ko00790,ko01100,ko01110,ko01130,map00630,map00790,map01100,map01110,map01130 M00126,M00840 R01334,R03504,R11037,R11073 RC00017,RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1MZ8Z@1224,2KMXM@206350,2VUVV@28216,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin HFDCGJPN_01142 580332.Slit_2000 2.2e-101 375.9 Nitrosomonadales oprM ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 Bacteria 1MUA8@1224,2VI5V@28216,44VTV@713636,COG1538@1,COG1538@2 NA|NA|NA M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family HFDCGJPN_01143 330214.NIDE0437 9.8e-50 203.0 Bacteria glbN ko:K06886 ko00000 Bacteria COG2346@1,COG2346@2 NA|NA|NA O COG2346, Truncated hemoglobins HFDCGJPN_01144 582744.Msip34_0540 6.7e-83 314.7 Nitrosomonadales Bacteria 1N5T4@1224,2KMJ5@206350,2VK22@28216,COG2206@1,COG2206@2 NA|NA|NA T Domain of unknown function (DUF3391) HFDCGJPN_01145 666681.M301_1123 3.9e-123 448.0 Nitrosomonadales fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MW0E@1224,2KKT0@206350,2VIJT@28216,COG0158@1,COG0158@2 NA|NA|NA G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 HFDCGJPN_01146 582744.Msip34_0960 2.1e-170 605.1 Nitrosomonadales aroG GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0684,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iYL1228.KPN_00758 Bacteria 1MU5Q@1224,2KKBA@206350,2VH4W@28216,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) HFDCGJPN_01147 582744.Msip34_0030 1.1e-155 556.2 Nitrosomonadales fre GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008047,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0019538,GO:0030091,GO:0030234,GO:0042602,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0050896,GO:0052875,GO:0055114,GO:0065007,GO:0065009,GO:0071704,GO:0098772,GO:1901564 1.16.1.3,1.17.1.1,1.18.1.2,1.19.1.1,1.5.1.41 ko:K00523,ko:K00528,ko:K02823,ko:K05368,ko:K18248,ko:K20256 ko00240,ko00520,ko00627,ko00740,ko00860,ko01100,ko01120,ko02024,map00240,map00520,map00627,map00740,map00860,map01100,map01120,map02024 M00637 R00097,R00823,R00825,R03391,R03392,R05705,R10159 RC00126,RC00192,RC00220,RC00230 br01602,ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3920,iSFxv_1172.SFxv_4273,iS_1188.S3832 Bacteria 1MV72@1224,2KKU7@206350,2VI9K@28216,COG0543@1,COG0543@2,COG1018@1,COG1018@2 NA|NA|NA C PFAM oxidoreductase FAD NAD(P)-binding domain protein HFDCGJPN_01148 582744.Msip34_0029 8e-35 153.3 Nitrosomonadales fxsA 2.3.3.13 ko:K01649,ko:K07113 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1NHHU@1224,2KN6I@206350,2VX8I@28216,COG3030@1,COG3030@2 NA|NA|NA S PFAM FxsA cytoplasmic membrane protein HFDCGJPN_01149 265072.Mfla_0029 4.4e-31 140.6 Nitrosomonadales cutA GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 4.2.3.1 ko:K01733,ko:K03926 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 1N6TN@1224,2KN3J@206350,2VUC8@28216,COG1324@1,COG1324@2 NA|NA|NA P PFAM CutA1 divalent ion tolerance protein HFDCGJPN_01150 666681.M301_0061 8.7e-185 653.7 Nitrosomonadales dsbD GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009266,GO:0009628,GO:0009898,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042221,GO:0042493,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071502,GO:0071840,GO:0071944,GO:0098552,GO:0098562,GO:0140096 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 iECSE_1348.ECSE_4435 Bacteria 1MU8W@1224,2KKIB@206350,2VI8I@28216,COG4232@1,COG4232@2 NA|NA|NA CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps HFDCGJPN_01151 1165096.ARWF01000001_gene1478 2.8e-46 191.8 Nitrosomonadales tlpA Bacteria 1MZ5J@1224,2KMY4@206350,2VU93@28216,COG0526@1,COG0526@2 NA|NA|NA CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_01152 265072.Mfla_0026 1.4e-56 225.7 Nitrosomonadales aroQ GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 3.4.13.9,4.2.1.10 ko:K01271,ko:K03785,ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000,ko01002 iIT341.HP1038,iJN746.PP_0560 Bacteria 1RDDT@1224,2KMU8@206350,2VR4Y@28216,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate HFDCGJPN_01153 1236959.BAMT01000017_gene2389 1.6e-55 222.2 Nitrosomonadales accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.3.1.12 ko:K00627,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 iYL1228.KPN_03664 Bacteria 1RCXA@1224,2KMQS@206350,2VR5S@28216,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA HFDCGJPN_01154 582744.Msip34_0023 3.6e-236 823.9 Nitrosomonadales accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.3.4.6,6.4.1.1,6.4.1.2 ko:K01941,ko:K01959,ko:K01961 ko00020,ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376,M00620 R00344,R00742,R00774,R04385 RC00040,RC00253,RC00367,RC00378 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4H@1224,2KM9C@206350,2VISB@28216,COG0439@1,COG0439@2 NA|NA|NA I PFAM Carbamoyl-phosphate synthase L chain HFDCGJPN_01155 265072.Mfla_0023 3.7e-133 481.1 Nitrosomonadales prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 ko:K02687 ko00000,ko01000,ko03009 Bacteria 1MUPC@1224,2KMH9@206350,2VH76@28216,COG2264@1,COG2264@2 NA|NA|NA J Methylates ribosomal protein L11 HFDCGJPN_01156 666681.M301_0055 1.4e-50 206.8 Nitrosomonadales Bacteria 1RGAU@1224,2A4J7@1,2KPB0@206350,2VU2M@28216,30T5U@2 NA|NA|NA S zinc-ribbon domain HFDCGJPN_01157 582744.Msip34_0019 3.3e-129 468.0 Nitrosomonadales oxyR ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1MVA1@1224,2KKKQ@206350,2VIBJ@28216,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family HFDCGJPN_01158 1132855.KB913035_gene440 0.0 1313.9 Nitrosomonadales katG 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 1MUBF@1224,2KKY1@206350,2VH5H@28216,COG0376@1,COG0376@2 NA|NA|NA P Peroxidase HFDCGJPN_01159 420662.Mpe_B0017 3.8e-30 137.9 unclassified Burkholderiales Bacteria 1KNUR@119065,1NBRN@1224,2E4CH@1,2VVBB@28216,32Z7Y@2 NA|NA|NA S PilZ domain HFDCGJPN_01160 666681.M301_0836 7.7e-53 213.0 Betaproteobacteria yodA Bacteria 1RHA5@1224,2VRCH@28216,COG1942@1,COG1942@2 NA|NA|NA S tautomerase HFDCGJPN_01161 1165096.ARWF01000001_gene1064 5.8e-107 394.0 Nitrosomonadales yyaM Bacteria 1MWSU@1224,2KMHS@206350,2VHP3@28216,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family HFDCGJPN_01162 1165096.ARWF01000001_gene557 1.7e-267 928.3 Nitrosomonadales ko:K09136 ko00000,ko03009 Bacteria 1MV7K@1224,2KKTK@206350,2VHZY@28216,COG1944@1,COG1944@2 NA|NA|NA O YcaO cyclodehydratase, ATP-ad Mg2+-binding HFDCGJPN_01163 666681.M301_0039 1.4e-121 442.6 Nitrosomonadales Bacteria 1MVAG@1224,2KNMV@206350,2VMU5@28216,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues HFDCGJPN_01164 666681.M301_0038 1.4e-131 475.7 Nitrosomonadales Bacteria 1MWAI@1224,2KNND@206350,2W251@28216,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues HFDCGJPN_01165 1122236.KB905142_gene573 1e-155 556.6 Nitrosomonadales Bacteria 1PNJV@1224,2KMPD@206350,2VI8H@28216,COG2358@1,COG2358@2 NA|NA|NA S NMT1-like family HFDCGJPN_01166 323850.Shew_1261 0.0 1454.1 Gammaproteobacteria 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1QJX4@1224,1RYVR@1236,COG1061@1,COG1061@2 NA|NA|NA KL type III restriction enzyme, res subunit HFDCGJPN_01167 502347.ESCAB7627_0695 6.5e-277 959.9 Escherichia 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1PCSG@1224,1TBY3@1236,3XRBA@561,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase HFDCGJPN_01168 1101195.Meth11DRAFT_0003 7e-60 236.5 Nitrosomonadales gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 1MVKT@1224,2KKEJ@206350,2VI8N@28216,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner HFDCGJPN_01170 1165096.ARWF01000001_gene595 2.1e-74 285.0 Nitrosomonadales ko:K09958 ko00000 Bacteria 1RA64@1224,2KNRG@206350,2VQAI@28216,COG3558@1,COG3558@2 NA|NA|NA S Protein of unknown function (DUF1348) HFDCGJPN_01171 582744.Msip34_0785 8.9e-73 280.4 Nitrosomonadales motB ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1MU4S@1224,2KMP0@206350,2VKC4@28216,COG1360@1,COG1360@2 NA|NA|NA N PFAM OmpA MotB domain protein HFDCGJPN_01172 265072.Mfla_1949 6.3e-86 323.9 Nitrosomonadales motC ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1MXK3@1224,2KKYS@206350,2VNCG@28216,COG1291@1,COG1291@2 NA|NA|NA N PFAM MotA TolQ ExbB proton channel HFDCGJPN_01173 582744.Msip34_0787 2.4e-106 391.7 Nitrosomonadales fliA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Bacteria 1MWEU@1224,2KKUV@206350,2VHR3@28216,COG1191@1,COG1191@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes HFDCGJPN_01174 1132855.KB913035_gene1300 2e-64 252.7 Nitrosomonadales fleN ko:K02282,ko:K04562 ko00000,ko02035,ko02044 Bacteria 1R8IW@1224,2KMU6@206350,2VRTK@28216,COG0455@1,COG0455@2 NA|NA|NA D Belongs to the ParA family HFDCGJPN_01175 582744.Msip34_0789 6.6e-142 510.8 Nitrosomonadales flhF ko:K02404 ko00000,ko02035 Bacteria 1MUQW@1224,2KKQQ@206350,2VHVZ@28216,COG1419@1,COG1419@2 NA|NA|NA N PFAM GTP-binding signal recognition particle SRP54 G- domain HFDCGJPN_01176 583345.Mmol_1268 8.6e-311 1072.4 Nitrosomonadales flhA GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0044085,GO:0044464,GO:0044780,GO:0044781,GO:0070925,GO:0071840,GO:0071944 ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1MUF3@1224,2KKSD@206350,2VHVC@28216,COG1298@1,COG1298@2 NA|NA|NA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin HFDCGJPN_01177 1165096.ARWF01000001_gene893 4.7e-136 491.1 Nitrosomonadales flhB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02401,ko:K02556,ko:K03229,ko:K04061,ko:K13820 ko02020,ko02030,ko02040,ko03070,map02020,map02030,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02000,ko02035,ko02044 1.A.30.1,3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 1MUWI@1224,2KMIP@206350,2VIH0@28216,COG1377@1,COG1377@2 NA|NA|NA N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin HFDCGJPN_01178 582744.Msip34_2108 5.8e-71 273.9 Nitrosomonadales 3.4.21.88 ko:K01356,ko:K03503 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1MW80@1224,2KMUY@206350,2VS2C@28216,COG1974@1,COG1974@2 NA|NA|NA L Peptidase S24-like HFDCGJPN_01180 153948.NAL212_2839 4.6e-116 427.2 Proteobacteria Bacteria 1MU7T@1224,COG2931@1,COG2931@2 NA|NA|NA Q COG2931, RTX toxins and related Ca2 -binding proteins HFDCGJPN_01181 153948.NAL212_2836 3.8e-145 521.2 Proteobacteria Bacteria 1QW33@1224,COG0457@1,COG0457@2 NA|NA|NA S TIGRFAM TIGR03032 family protein HFDCGJPN_01182 583345.Mmol_0406 2e-188 665.2 Nitrosomonadales yhjE Bacteria 1MU46@1224,2KKC4@206350,2VJXD@28216,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter HFDCGJPN_01183 582744.Msip34_0462 9.3e-124 449.9 Nitrosomonadales murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1MXDH@1224,2KKDP@206350,2VI7I@28216,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation HFDCGJPN_01184 1236959.BAMT01000002_gene2126 5.1e-27 126.7 Nitrosomonadales murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iECP_1309.ECP_0093,iJN678.murC Bacteria 1MV68@1224,2KMBW@206350,2VIKZ@28216,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family HFDCGJPN_01185 666681.M301_1932 7.2e-65 253.4 Nitrosomonadales dsbB ko:K03611 ko00000,ko03110 5.A.2.1 Bacteria 1RIJE@1224,2KMR0@206350,2VREE@28216,COG1495@1,COG1495@2 NA|NA|NA O Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein HFDCGJPN_01186 1502770.JQMG01000001_gene134 1.2e-150 539.7 Nitrosomonadales xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUA4@1224,2KKEN@206350,2VJIC@28216,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides HFDCGJPN_01187 339670.Bamb_0401 1.9e-134 485.7 Burkholderiaceae hemK1 Bacteria 1K32W@119060,1MV12@1224,2VJVT@28216,COG2890@1,COG2890@2 NA|NA|NA J Pfam Methyltransferase small HFDCGJPN_01188 1165096.ARWF01000001_gene108 2.4e-56 226.9 Nitrosomonadales Bacteria 1R4DM@1224,2DBUQ@1,2KN21@206350,2W7ZY@28216,2ZB76@2 NA|NA|NA HFDCGJPN_01189 582744.Msip34_0934 2.3e-294 1017.7 Nitrosomonadales kup ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1MUVH@1224,2KKXI@206350,2VH9I@28216,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell HFDCGJPN_01190 582744.Msip34_0933 6.5e-119 433.7 Nitrosomonadales Z012_09445 Bacteria 1MUNA@1224,2KKPW@206350,2VHTB@28216,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 HFDCGJPN_01191 582744.Msip34_0932 2.7e-138 498.0 Nitrosomonadales dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1MU0Y@1224,2KMF7@206350,2VHUX@28216,COG2171@1,COG2171@2 NA|NA|NA E Belongs to the transferase hexapeptide repeat family HFDCGJPN_01192 1387312.BAUS01000002_gene622 1.9e-40 171.8 Nitrosomonadales yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1MZ6S@1224,2KMXQ@206350,2VUB7@28216,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family HFDCGJPN_01193 1387312.BAUS01000002_gene621 6.6e-191 673.3 Nitrosomonadales dapE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2485,iIT341.HP0212 Bacteria 1MW6G@1224,2KMC3@206350,2VHRF@28216,COG0624@1,COG0624@2 NA|NA|NA E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls HFDCGJPN_01194 582744.Msip34_0929 1.5e-145 522.3 Nitrosomonadales prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1MX8Q@1224,2KMDB@206350,2VIPK@28216,COG2890@1,COG2890@2 NA|NA|NA J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue HFDCGJPN_01196 582744.Msip34_0925 1.5e-136 492.7 Nitrosomonadales rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 ko00000,ko01000,ko03009 Bacteria 1MUCE@1224,2KKN3@206350,2VITB@28216,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family HFDCGJPN_01197 582744.Msip34_0924 3.3e-76 291.2 Nitrosomonadales scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1PUA6@1224,2KKY9@206350,2VKIN@28216,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves HFDCGJPN_01198 582744.Msip34_0923 1.8e-107 395.6 Nitrosomonadales scpA ko:K05896 ko00000,ko03036 Bacteria 1MVCN@1224,2KKSY@206350,2VKE7@28216,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves HFDCGJPN_01199 582744.Msip34_0921 1e-218 765.8 Nitrosomonadales trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MV4T@1224,2KKSF@206350,2VIEY@28216,COG0180@1,COG0180@2 NA|NA|NA J TIGRFAM tryptophanyl-tRNA synthetase HFDCGJPN_01200 1502770.JQMG01000001_gene151 2.1e-72 278.9 Nitrosomonadales ywhC ko:K06402 ko00000,ko01000,ko01002 Bacteria 1NSFF@1224,2KKUP@206350,2VHAM@28216,COG1994@1,COG1994@2 NA|NA|NA S Peptidase family M50 HFDCGJPN_01201 582744.Msip34_0986 5.4e-103 380.6 Nitrosomonadales pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1MXQC@1224,2KM5D@206350,2VQ3B@28216,COG2518@1,COG2518@2 NA|NA|NA O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins HFDCGJPN_01202 582744.Msip34_0987 2.1e-113 415.2 Nitrosomonadales surE GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 iSFxv_1172.SFxv_3035 Bacteria 1MVHE@1224,2KKQA@206350,2VIND@28216,COG0496@1,COG0496@2 NA|NA|NA S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates HFDCGJPN_01203 1165096.ARWF01000001_gene2355 5e-41 173.7 Nitrosomonadales Bacteria 1N1EF@1224,2KN33@206350,2VU3C@28216,COG3308@1,COG3308@2 NA|NA|NA S Predicted membrane protein (DUF2069) HFDCGJPN_01204 666681.M301_0679 8e-86 323.6 Nitrosomonadales ko:K07226 ko00000 Bacteria 1RFVC@1224,2KKEX@206350,2VS07@28216,COG0748@1,COG0748@2 NA|NA|NA P PFAM Pyridoxamine 5'-phosphate HFDCGJPN_01205 1132855.KB913035_gene2064 3.9e-94 350.9 Nitrosomonadales wrbA 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1MW7N@1224,2KM4I@206350,2VJMC@28216,COG0655@1,COG0655@2 NA|NA|NA S Belongs to the WrbA family HFDCGJPN_01206 1165096.ARWF01000001_gene2357 3.7e-77 295.0 Nitrosomonadales MA20_15040 Bacteria 1MX5C@1224,2KMPC@206350,2VJXE@28216,COG1432@1,COG1432@2 NA|NA|NA S OST-HTH/LOTUS domain HFDCGJPN_01207 666681.M301_0683 4.7e-228 797.0 Nitrosomonadales purB GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510 Bacteria 1MV4B@1224,2KKN0@206350,2VI2T@28216,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily HFDCGJPN_01208 1538295.JY96_10645 2.9e-194 685.6 unclassified Burkholderiales yegE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.7.65 ko:K21084 ko02026,map02026 ko00000,ko00001,ko01000 Bacteria 1KKRI@119065,1MU2C@1224,2VJMN@28216,COG5001@1,COG5001@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_01209 582744.Msip34_0993 3.1e-15 87.8 Nitrosomonadales Bacteria 1QC1F@1224,2APM8@1,2KN6A@206350,2W80E@28216,31EQK@2 NA|NA|NA HFDCGJPN_01210 207954.MED92_09586 3.3e-24 118.6 Bacteria Bacteria COG4254@1,COG4254@2 NA|NA|NA UW PFAM FecR protein HFDCGJPN_01211 1165096.ARWF01000001_gene1062 8.8e-177 626.7 Nitrosomonadales Bacteria 1MWXZ@1224,2KP5P@206350,2VN35@28216,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily HFDCGJPN_01212 1165096.ARWF01000001_gene2049 1.1e-29 136.3 Betaproteobacteria Bacteria 1RIFX@1224,2ATZM@1,2VSS3@28216,31JJE@2 NA|NA|NA HFDCGJPN_01213 666681.M301_2412 3.2e-183 647.9 Nitrosomonadales cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1MU2X@1224,2KKXV@206350,2VIN5@28216,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases HFDCGJPN_01214 582744.Msip34_0470 8.3e-131 473.4 Nitrosomonadales 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 R11945 RC00061 ko00000,ko00001,ko01000 Bacteria 1MW54@1224,2KMG6@206350,2VIBZ@28216,COG0702@1,COG0702@2 NA|NA|NA GM Saccharopine dehydrogenase NADP binding domain HFDCGJPN_01215 582744.Msip34_0469 1.9e-241 842.0 Nitrosomonadales slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K08309 ko00000,ko01000,ko01011 GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 Bacteria 1MV3F@1224,2KKTQ@206350,2VHPK@28216,COG0741@1,COG0741@2 NA|NA|NA M Soluble lytic murein transglycosylase L domain HFDCGJPN_01216 582744.Msip34_0468 9.2e-15 85.5 Nitrosomonadales Bacteria 1P8GA@1224,2DFW3@1,2KP3G@206350,2W65E@28216,2ZTE4@2 NA|NA|NA HFDCGJPN_01217 582744.Msip34_0467 4.9e-152 543.9 Nitrosomonadales lpxC GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 ko:K02535,ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 M00060,M00083 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 iECS88_1305.ECS88_0100 Bacteria 1MV6T@1224,2KKCT@206350,2VHI8@28216,COG0774@1,COG0774@2 NA|NA|NA M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis HFDCGJPN_01218 582744.Msip34_0466 5.3e-196 690.3 Nitrosomonadales ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1MV2X@1224,2KKNM@206350,2VH0S@28216,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity HFDCGJPN_01219 582744.Msip34_0465 5.6e-212 743.4 Nitrosomonadales ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1MUSR@1224,2KKH3@206350,2VGZP@28216,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring HFDCGJPN_01220 582744.Msip34_0464 2.2e-102 378.6 Nitrosomonadales ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 ko:K01921,ko:K03589 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 1N0T7@1224,2KKS9@206350,2VRMV@28216,COG1589@1,COG1589@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly HFDCGJPN_01221 582744.Msip34_0463 1.2e-62 245.7 Nitrosomonadales ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 iECO26_1355.ECO26_0095 Bacteria 1MUTB@1224,2KKG2@206350,2VHIW@28216,COG1181@1,COG1181@2 NA|NA|NA M Cell wall formation HFDCGJPN_01222 582744.Msip34_0956 3.3e-74 284.6 Proteobacteria eat ko:K16238 ko00000,ko02000 2.A.3.5 Bacteria 1QUC6@1224,COG1113@1,COG1113@2 NA|NA|NA E amino acid HFDCGJPN_01223 582744.Msip34_0957 7.7e-234 816.2 Nitrosomonadales eutB 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 R00749 RC00370 ko00000,ko00001,ko01000 Bacteria 1MUR4@1224,2KNEH@206350,2VIJW@28216,COG4303@1,COG4303@2 NA|NA|NA E PFAM Ethanolamine ammonia lyase large subunit HFDCGJPN_01224 666681.M301_2691 1.8e-99 369.0 Nitrosomonadales eutC GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0009350,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 R00749 RC00370 ko00000,ko00001,ko01000 Bacteria 1MWQI@1224,2KNF8@206350,2VJ8Y@28216,COG4302@1,COG4302@2 NA|NA|NA H PFAM Ethanolamine ammonia-lyase light chain HFDCGJPN_01225 582744.Msip34_0961 1.8e-83 316.2 Nitrosomonadales ko:K04033 ko00000,ko03000 Bacteria 1Q3UX@1224,2KN8B@206350,2VT4I@28216,COG2207@1,COG2207@2 NA|NA|NA K SMART helix-turn-helix- domain containing protein AraC type HFDCGJPN_01226 582744.Msip34_0962 8.8e-195 686.4 Nitrosomonadales rlmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1MV3A@1224,2KKG7@206350,2VHJ8@28216,COG2265@1,COG2265@2 NA|NA|NA J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA HFDCGJPN_01228 265072.Mfla_1850 5.6e-171 607.4 Nitrosomonadales appA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MUZH@1224,2KM4S@206350,2VHCV@28216,COG0747@1,COG0747@2 NA|NA|NA E PFAM extracellular solute-binding protein family 5 HFDCGJPN_01229 582744.Msip34_0966 1.2e-56 226.1 Nitrosomonadales erfK Bacteria 1RHBG@1224,2KMQ4@206350,2VQT7@28216,COG1376@1,COG1376@2 NA|NA|NA S PFAM ErfK YbiS YcfS YnhG family protein HFDCGJPN_01230 265072.Mfla_1848 1.1e-119 436.4 Nitrosomonadales ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MU8Z@1224,2KP5S@206350,2VJJU@28216,COG0601@1,COG0601@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component HFDCGJPN_01231 1236959.BAMT01000003_gene579 6.9e-99 367.1 Nitrosomonadales dppC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MW3R@1224,2KM6B@206350,2W24J@28216,COG1173@1,COG1173@2 NA|NA|NA P PFAM binding-protein-dependent transport systems inner membrane component HFDCGJPN_01232 582744.Msip34_0969 2.1e-102 378.6 Nitrosomonadales yhhQ ko:K09125 ko00000 Bacteria 1NIPE@1224,2KM8N@206350,2VH6D@28216,COG1738@1,COG1738@2 NA|NA|NA S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage HFDCGJPN_01233 582744.Msip34_0970 6.1e-167 593.6 Nitrosomonadales nagZ GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 2.7.8.7,3.2.1.21,3.2.1.52 ko:K00997,ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00770,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00770,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R01625,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00002,RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 GH3 iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790 Bacteria 1MVAJ@1224,2KKJB@206350,2VHAR@28216,COG1472@1,COG1472@2 NA|NA|NA G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides HFDCGJPN_01234 582744.Msip34_0971 6.7e-90 337.0 Nitrosomonadales yccA ko:K06890,ko:K19416 M00742 ko00000,ko00002,ko02000 1.A.14.2.1 Bacteria 1MU69@1224,2KMJ9@206350,2VKZV@28216,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family HFDCGJPN_01235 1236959.BAMT01000007_gene2736 1.7e-101 375.9 Nitrosomonadales Z012_00845 Bacteria 1N0C1@1224,2KKY3@206350,2VM51@28216,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family HFDCGJPN_01236 1502770.JQMG01000001_gene1434 1.9e-72 278.5 Nitrosomonadales iorA 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 1RD8C@1224,2KMW6@206350,2VQ9M@28216,COG2080@1,COG2080@2 NA|NA|NA C PFAM 2Fe-2S -binding domain protein HFDCGJPN_01237 582744.Msip34_0657 2.3e-102 378.3 Nitrosomonadales pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU2U@1224,2KKFS@206350,2VI6G@28216,COG1249@1,COG1249@2 NA|NA|NA C pyridine nucleotide-disulphide oxidoreductase dimerisation HFDCGJPN_01238 1278309.KB907101_gene547 1.2e-44 186.4 Oceanospirillales Bacteria 1RM1M@1224,1SF8A@1236,1XPGA@135619,2BPVC@1,32IP1@2 NA|NA|NA HFDCGJPN_01239 1278309.KB907101_gene546 4.3e-42 177.9 Oceanospirillales Bacteria 1RKVW@1224,1SDSV@1236,1XPPV@135619,2CZND@1,32T6R@2 NA|NA|NA HFDCGJPN_01240 1132855.KB913035_gene2166 1.4e-36 159.5 Nitrosomonadales Bacteria 1N539@1224,2E1J6@1,2KNYF@206350,2VUGG@28216,32WWW@2 NA|NA|NA HFDCGJPN_01242 1120792.JAFV01000001_gene18 1.6e-18 101.3 Proteobacteria Bacteria 1MU7T@1224,COG2931@1,COG2931@2 NA|NA|NA Q COG2931, RTX toxins and related Ca2 -binding proteins HFDCGJPN_01243 383407.XOC_2830 1.1e-29 136.7 Xanthomonadales ko:K12262 ko00000 Bacteria 1MZ7X@1224,1S5MD@1236,1X7R8@135614,COG3038@1,COG3038@2 NA|NA|NA C Prokaryotic cytochrome b561 HFDCGJPN_01244 666681.M301_0043 1.5e-178 632.5 Betaproteobacteria 1.16.9.1 ko:K20150 ko00000,ko01000 Bacteria 1QCH9@1224,28JQB@1,2VJJF@28216,2Z9G8@2 NA|NA|NA HFDCGJPN_01245 1538295.JY96_02000 5.5e-30 137.1 Betaproteobacteria ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 1MZGS@1224,2VVQN@28216,COG3474@1,COG3474@2 NA|NA|NA C Cytochrome c HFDCGJPN_01246 265072.Mfla_1748 0.0 1926.8 Nitrosomonadales mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUXG@1224,2KKSG@206350,2VI7M@28216,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site HFDCGJPN_01247 1236959.BAMT01000012_gene3036 3.3e-12 77.8 Nitrosomonadales Bacteria 1NGVT@1224,2ENVQ@1,2KND3@206350,2VY6X@28216,33GGS@2 NA|NA|NA S Protein of unknown function (DUF2934) HFDCGJPN_01248 582744.Msip34_1246 1.3e-252 878.6 Nitrosomonadales tldD ko:K03568 ko00000,ko01002 Bacteria 1MUSK@1224,2KKXM@206350,2VHJ9@28216,COG0312@1,COG0312@2 NA|NA|NA S PFAM peptidase U62 modulator of DNA gyrase HFDCGJPN_01249 582744.Msip34_1247 3.5e-136 491.1 Nitrosomonadales ramA 3.5.1.77,3.5.5.1 ko:K01459,ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 Bacteria 1MUUB@1224,2KKUS@206350,2VIR4@28216,COG0388@1,COG0388@2 NA|NA|NA S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase HFDCGJPN_01250 582744.Msip34_1248 0.0 1682.5 Nitrosomonadales yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 1MXWF@1224,2KKF5@206350,2VH52@28216,COG3164@1,COG3164@2 NA|NA|NA S Protein of unknown function HFDCGJPN_01251 582744.Msip34_1249 2.8e-279 967.6 Nitrosomonadales yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06158 ko00000,ko03012 Bacteria 1MU37@1224,2KKQI@206350,2VHGH@28216,COG0488@1,COG0488@2 NA|NA|NA S PFAM ABC transporter HFDCGJPN_01252 265072.Mfla_1742 6.7e-64 250.4 Nitrosomonadales Bacteria 1PJFT@1224,2A8HR@1,2KMSG@206350,2W7Z0@28216,30XJW@2 NA|NA|NA HFDCGJPN_01253 1502770.JQMG01000001_gene1806 1.8e-24 119.4 Nitrosomonadales Bacteria 1N6PJ@1224,2KNAC@206350,2VW8V@28216,COG3678@1,COG3678@2 NA|NA|NA NPTU LTXXQ motif family protein HFDCGJPN_01255 582744.Msip34_1253 1.3e-88 332.8 Nitrosomonadales Bacteria 1MVCB@1224,2KMK4@206350,2VJB0@28216,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_01256 582744.Msip34_1254 2.4e-121 442.6 Nitrosomonadales 2.7.13.3 ko:K02484,ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1N17V@1224,2KMEA@206350,2WEJE@28216,COG0642@1,COG2205@2,COG2770@1,COG2770@2 NA|NA|NA T PhoQ Sensor HFDCGJPN_01257 1132855.KB913035_gene1176 1.8e-34 152.1 Nitrosomonadales ychJ ko:K09858 ko00000 Bacteria 1MZZK@1224,2KN6D@206350,2VTZE@28216,COG3012@1,COG3012@2 NA|NA|NA S Belongs to the UPF0225 family HFDCGJPN_01258 1502770.JQMG01000001_gene2279 1.4e-34 152.9 Betaproteobacteria Bacteria 1NK9M@1224,2EI0V@1,2VY7B@28216,33BSC@2 NA|NA|NA HFDCGJPN_01259 265072.Mfla_1737 4.2e-281 973.4 Nitrosomonadales prfC GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837 ko00000,ko03012 Bacteria 1MU7X@1224,2KKIK@206350,2VIV3@28216,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP HFDCGJPN_01260 583345.Mmol_0808 1.5e-89 335.9 Nitrosomonadales blh Bacteria 1MURA@1224,2KM3H@206350,2VJYK@28216,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily HFDCGJPN_01261 582744.Msip34_1583 1.9e-29 135.2 Nitrosomonadales bigR Bacteria 1N72Q@1224,2KN5Z@206350,2VU9V@28216,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor HFDCGJPN_01262 1101195.Meth11DRAFT_1769 1.8e-30 139.0 Nitrosomonadales blh 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 1N9AF@1224,2KN8F@206350,2VU0V@28216,COG3453@1,COG3453@2 NA|NA|NA S Putative phosphatase (DUF442) HFDCGJPN_01263 1235457.C404_11900 6.7e-65 254.2 Burkholderiaceae ko:K07090 ko00000 Bacteria 1K3RD@119060,1MVBS@1224,2VQ23@28216,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein HFDCGJPN_01264 582744.Msip34_1577 0.0 1199.1 Nitrosomonadales acsA 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MUF5@1224,2KMJG@206350,2VIP3@28216,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA HFDCGJPN_01265 582744.Msip34_1576 0.0 1208.4 Nitrosomonadales glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 1MU4I@1224,2KKKX@206350,2VH5B@28216,COG1391@1,COG1391@2 NA|NA|NA OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell HFDCGJPN_01267 1211115.ALIQ01000175_gene3640 6.9e-22 110.2 Beijerinckiaceae parA ko:K03496,ko:K12055 ko00000,ko02044,ko03036,ko04812 3.A.7.11.1 Bacteria 1MV43@1224,2TSWH@28211,3N9Z0@45404,COG1192@1,COG1192@2 NA|NA|NA D Anion-transporting ATPase HFDCGJPN_01268 582744.Msip34_0188 1.3e-57 229.6 Nitrosomonadales Bacteria 1RFY7@1224,29CX4@1,2KN1E@206350,2VR98@28216,2ZZV8@2 NA|NA|NA S Domain of unknown function (DUF4390) HFDCGJPN_01269 582744.Msip34_0187 7.3e-162 577.0 Nitrosomonadales sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1MWPE@1224,2KKZV@206350,2VI4V@28216,COG0144@1,COG0144@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA HFDCGJPN_01270 582744.Msip34_0186 7.1e-126 456.8 Nitrosomonadales htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1MUV4@1224,2KP6G@206350,2VIVB@28216,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 HFDCGJPN_01271 582744.Msip34_0185 8.2e-131 473.4 Nitrosomonadales fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 1MU4Q@1224,2KMBC@206350,2VIS2@28216,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus HFDCGJPN_01272 582744.Msip34_0184 3.5e-72 277.7 Nitrosomonadales def GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 1RA2P@1224,2KMM5@206350,2VQ4N@28216,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions HFDCGJPN_01273 265072.Mfla_0188 5.6e-118 431.0 Nitrosomonadales lysM Bacteria 1MUBV@1224,2KMAE@206350,2VIZJ@28216,COG1652@1,COG1652@2 NA|NA|NA S Lysin motif HFDCGJPN_01274 1165096.ARWF01000001_gene1383 2e-128 465.7 Nitrosomonadales dprA ko:K04096 ko00000 Bacteria 1MVF6@1224,2KKV6@206350,2VH3W@28216,COG0758@1,COG0758@2 NA|NA|NA LU TIGRFAM DNA protecting protein DprA HFDCGJPN_01275 582744.Msip34_0181 4.5e-58 230.7 Nitrosomonadales smg ko:K03747 ko00000 Bacteria 1RD5F@1224,2KMZS@206350,2VRJF@28216,COG2922@1,COG2922@2 NA|NA|NA S Belongs to the Smg family HFDCGJPN_01276 265072.Mfla_0191 1.3e-122 446.0 Nitrosomonadales metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 1MUC9@1224,2KKNI@206350,2VHHI@28216,COG0685@1,COG0685@2 NA|NA|NA E TIGRFAM 5,10-methylenetetrahydrofolate reductase HFDCGJPN_01277 1236959.BAMT01000006_gene369 4.6e-39 167.2 Nitrosomonadales yvlD ko:K08972 ko00000 Bacteria 1N1DF@1224,2KN4A@206350,2VUY1@28216,COG1950@1,COG1950@2 NA|NA|NA S PFAM Membrane protein of HFDCGJPN_01278 582744.Msip34_0178 5e-257 893.3 Nitrosomonadales ahcY GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 1MUQ2@1224,2KMCP@206350,2VH57@28216,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine HFDCGJPN_01279 582744.Msip34_0177 4.7e-155 554.3 Nitrosomonadales Bacteria 1MW7F@1224,2KMAH@206350,2VHR0@28216,COG2206@1,COG2206@2 NA|NA|NA T PFAM metal-dependent phosphohydrolase HD sub domain HFDCGJPN_01280 582744.Msip34_0176 5.2e-204 716.8 Nitrosomonadales metK GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 iJN746.PP_4967,iYL1228.KPN_03375 Bacteria 1MUFQ@1224,2KKEB@206350,2VH7U@28216,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme HFDCGJPN_01281 1236959.BAMT01000006_gene374 1.9e-105 389.0 Nitrosomonadales htrB 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1Q41N@1224,2KKVS@206350,2VKN0@28216,COG1560@1,COG1560@2 NA|NA|NA M lipid A biosynthesis acyltransferase HFDCGJPN_01282 1236959.BAMT01000006_gene375 7.5e-112 410.2 Nitrosomonadales dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_4494 Bacteria 1MWDH@1224,2KM39@206350,2VI0C@28216,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan HFDCGJPN_01283 265072.Mfla_0197 3.7e-77 294.7 Nitrosomonadales yigA ko:K09921 ko00000 Bacteria 1R4BP@1224,2KMSU@206350,2VPN6@28216,COG3159@1,COG3159@2 NA|NA|NA S Protein of unknown function, DUF484 HFDCGJPN_01284 1101195.Meth11DRAFT_0228 1.5e-110 406.0 Nitrosomonadales xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 ko:K03733 ko00000,ko03036 Bacteria 1MUJJ@1224,2KKM7@206350,2VJ5V@28216,COG4973@1,COG4973@2 NA|NA|NA L Belongs to the 'phage' integrase family. XerC subfamily HFDCGJPN_01285 1132855.KB913035_gene370 1.7e-102 378.6 Nitrosomonadales sodB GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 ko:K03601,ko:K04564 ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000,ko03400 iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050 Bacteria 1MVW2@1224,2KMIN@206350,2VI2Y@28216,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems HFDCGJPN_01287 582744.Msip34_0169 4.3e-265 920.6 Nitrosomonadales irp ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QTS8@1224,2KM9M@206350,2WGGE@28216,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor HFDCGJPN_01288 159087.Daro_1865 1.5e-16 92.0 Betaproteobacteria Bacteria 1NFHG@1224,2EC8Y@1,2VWKX@28216,3367B@2 NA|NA|NA HFDCGJPN_01289 1538295.JY96_21090 2.6e-36 158.3 unclassified Burkholderiales gstF 2.5.1.18 ko:K00799,ko:K04750 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1KNSY@119065,1MZ7K@1224,2VTMF@28216,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein HFDCGJPN_01291 666681.M301_2684 3.5e-118 431.8 Nitrosomonadales nnrS ko:K07234 ko00000 Bacteria 1MUJK@1224,2KNIV@206350,2VJ75@28216,COG3213@1,COG3213@2 NA|NA|NA P NnrS protein HFDCGJPN_01292 635013.TherJR_0994 1.8e-46 192.6 Peptococcaceae Bacteria 1TP8V@1239,247PX@186801,26021@186807,COG5001@1,COG5001@2 NA|NA|NA T Diguanylate cyclase HFDCGJPN_01294 582744.Msip34_0386 3.4e-103 381.3 Nitrosomonadales cinA 3.5.1.42 ko:K03742 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1MVG6@1224,2KM94@206350,2VHTD@28216,COG1058@1,COG1058@2 NA|NA|NA S molybdopterin binding domain HFDCGJPN_01295 582744.Msip34_0388 8.6e-303 1045.8 Nitrosomonadales polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1MU31@1224,2KM0Q@206350,2VJ57@28216,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity HFDCGJPN_01296 666681.M301_1397 1.3e-121 442.6 Nitrosomonadales ko:K03521 ko00000 iAF987.Gmet_2266 Bacteria 1MYID@1224,2KMHE@206350,2W131@28216,COG2086@1,COG2086@2 NA|NA|NA C Electron transfer flavoprotein domain HFDCGJPN_01297 1267005.KB911260_gene3382 2.7e-11 76.3 Alphaproteobacteria Bacteria 1NDIB@1224,2VFW3@28211,COG1413@1,COG1413@2 NA|NA|NA C lyase activity HFDCGJPN_01298 1132855.KB913035_gene1379 1.5e-203 715.7 Nitrosomonadales sulP GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 ko:K03321 ko00000,ko02000 2.A.53.3 iSbBS512_1146.SbBS512_E1370 Bacteria 1MVWV@1224,2KM4W@206350,2VH45@28216,COG0659@1,COG0659@2 NA|NA|NA P STAS domain HFDCGJPN_01299 1223521.BBJX01000001_gene1014 4.1e-56 224.6 Comamonadaceae pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1RE75@1224,2VRMZ@28216,4AHJ8@80864,COG2065@1,COG2065@2 NA|NA|NA F Phosphoribosyl transferase domain HFDCGJPN_01301 1131553.JIBI01000043_gene1927 9.8e-12 76.6 Nitrosomonadales Bacteria 1Q88K@1224,295E6@1,2WBMJ@28216,2ZSRZ@2,373EF@32003 NA|NA|NA HFDCGJPN_01303 583345.Mmol_1925 5.6e-63 247.7 Betaproteobacteria 2.7.7.65 ko:K13069 R08057 ko00000,ko01000 Bacteria 1MZV7@1224,2WEG8@28216,COG2199@1,COG3706@2 NA|NA|NA T PFAM GGDEF domain containing protein HFDCGJPN_01304 1492738.FEM21_16780 9.5e-81 307.0 Flavobacterium modC 3.6.3.29 ko:K02017,ko:K02018 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 Bacteria 1IKAP@117743,2NUZQ@237,4PMQA@976,COG1118@1,COG1118@2 NA|NA|NA P SMART ATPases associated with a variety of cellular activities HFDCGJPN_01305 1095769.CAHF01000006_gene1733 1.4e-76 292.7 Oxalobacteraceae modB ko:K02018,ko:K15496 ko02010,map02010 M00189,M00423 ko00000,ko00001,ko00002,ko02000 3.A.1.6.5,3.A.1.8 Bacteria 1MUXR@1224,2VIZW@28216,4731K@75682,COG4149@1,COG4149@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component HFDCGJPN_01306 653733.Selin_1853 2e-17 95.5 Bacteria modE ko:K02019 ko00000,ko03000 Bacteria COG4148@1,COG4148@2 NA|NA|NA P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system HFDCGJPN_01307 1122236.KB905142_gene387 1.1e-96 359.8 Nitrosomonadales modA ko:K02020 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria 1MVNA@1224,2KN5C@206350,2VJEC@28216,COG0725@1,COG0725@2 NA|NA|NA P Bacterial extracellular solute-binding protein HFDCGJPN_01308 582744.Msip34_2149 1.3e-106 393.7 Nitrosomonadales ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 1R9AP@1224,2KNN1@206350,2W0HU@28216,COG3746@1,COG3746@2 NA|NA|NA P PFAM phosphate-selective porin O and P HFDCGJPN_01309 1434929.X946_3555 7.9e-66 257.3 Burkholderiaceae modE ko:K02019,ko:K05772 ko02010,map02010 M00186 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.6.2,3.A.1.6.4 Bacteria 1K2CT@119060,1P9SX@1224,2VMCH@28216,COG2005@1,COG2005@2,COG3585@1,COG3585@2 NA|NA|NA H Transcriptional regulator HFDCGJPN_01310 1165096.ARWF01000001_gene1079 4.3e-118 431.4 Nitrosomonadales ko:K07168 ko00000 Bacteria 1MXJG@1224,2KKFG@206350,2VJU5@28216,COG3448@1,COG3448@2 NA|NA|NA T PFAM HPP family protein HFDCGJPN_01311 265072.Mfla_1261 6.3e-48 196.8 Nitrosomonadales rmuC ko:K09760 ko00000 Bacteria 1MWHV@1224,2KM0V@206350,2VJVZ@28216,COG1322@1,COG1322@2 NA|NA|NA S RmuC family HFDCGJPN_01312 1236959.BAMT01000009_gene3419 1.1e-11 75.5 Nitrosomonadales Bacteria 1PBPJ@1224,2CDES@1,2KP26@206350,2W86H@28216,2ZXEB@2 NA|NA|NA HFDCGJPN_01313 1132855.KB913035_gene1675 1.2e-20 105.5 Nitrosomonadales moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 ko:K03636,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 1N0IE@1224,2KN73@206350,2VVSP@28216,COG1977@1,COG1977@2 NA|NA|NA H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin HFDCGJPN_01314 582744.Msip34_1730 1e-54 219.5 Nitrosomonadales moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1305,iEC042_1314.EC042_0869,iEC55989_1330.EC55989_0828,iECABU_c1320.ECABU_c08270,iECED1_1282.ECED1_0750,iECIAI1_1343.ECIAI1_0820,iECIAI39_1322.ECIAI39_0761,iECNA114_1301.ECNA114_0717,iECO103_1326.ECO103_0820,iECO111_1330.ECO111_0846,iECO26_1355.ECO26_0911,iECOK1_1307.ECOK1_0787,iECP_1309.ECP_0799,iECS88_1305.ECS88_0802,iECSE_1348.ECSE_0839,iECSF_1327.ECSF_0711,iECW_1372.ECW_m0841,iEKO11_1354.EKO11_3101,iEcE24377_1341.EcE24377A_0848,iG2583_1286.G2583_1013,iLF82_1304.LF82_1369,iNRG857_1313.NRG857_03500,iSSON_1240.SSON_0764,iUMN146_1321.UM146_13720,iUTI89_1310.UTI89_C0785,iWFL_1372.ECW_m0841,ic_1306.c0867 Bacteria 1RGUX@1224,2KMVK@206350,2VRMG@28216,COG0314@1,COG0314@2 NA|NA|NA H PFAM molybdopterin biosynthesis MoaE protein HFDCGJPN_01315 666681.M301_2610 1.9e-63 248.8 Nitrosomonadales lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 Bacteria 1MU6A@1224,2KMMM@206350,2VQ1Y@28216,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate HFDCGJPN_01316 1165096.ARWF01000001_gene1790 1e-30 139.4 Nitrosomonadales ybeD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K09158 ko00000 Bacteria 1RGV5@1224,2KN2V@206350,2VTY5@28216,COG2921@1,COG2921@2 NA|NA|NA S Protein of unknown function (DUF493) HFDCGJPN_01317 582744.Msip34_2539 3.5e-155 554.7 Nitrosomonadales dacC 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1MUU7@1224,2KM20@206350,2VH46@28216,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family HFDCGJPN_01318 1236959.BAMT01000002_gene1842 3.3e-88 332.0 Nitrosomonadales rlpA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 ko:K03642 ko00000 Bacteria 1MZ8S@1224,2KKXH@206350,2VJAN@28216,COG0797@1,COG0797@2,COG3087@1,COG3087@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides HFDCGJPN_01319 582744.Msip34_2537 2.6e-160 571.6 Nitrosomonadales mrdB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K05837 ko00000,ko03036 Bacteria 1MUK3@1224,2KKVQ@206350,2VH8Q@28216,COG0772@1,COG0772@2 NA|NA|NA M Peptidoglycan polymerase that is essential for cell wall elongation HFDCGJPN_01320 582744.Msip34_2536 4.2e-291 1006.9 Nitrosomonadales mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 Bacteria 1MV8C@1224,2KM2T@206350,2VHBZ@28216,COG0768@1,COG0768@2 NA|NA|NA M Catalyzes cross-linking of the peptidoglycan cell wall HFDCGJPN_01321 265072.Mfla_2493 2.3e-52 211.8 Nitrosomonadales mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1RBNF@1224,2KN0S@206350,2VQQ3@28216,COG2891@1,COG2891@2 NA|NA|NA M TIGRFAM rod shape-determining protein MreD HFDCGJPN_01322 582744.Msip34_2534 1.7e-115 422.5 Nitrosomonadales mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1N8ZS@1224,2KM0G@206350,2VK0Y@28216,COG1792@1,COG1792@2 NA|NA|NA M shape-determining protein MreC HFDCGJPN_01323 582744.Msip34_2533 2.9e-185 654.4 Nitrosomonadales mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1MUMW@1224,2KKND@206350,2VIR9@28216,COG1077@1,COG1077@2 NA|NA|NA D TIGRFAM cell shape determining protein, MreB Mrl family HFDCGJPN_01324 583345.Mmol_2252 1.8e-37 161.8 Nitrosomonadales gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1MZQP@1224,2KN54@206350,2VUFB@28216,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) HFDCGJPN_01325 582744.Msip34_2531 7e-238 829.7 Nitrosomonadales gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1MUVQ@1224,2KKBX@206350,2VIG3@28216,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) HFDCGJPN_01326 1502770.JQMG01000001_gene75 9.3e-250 869.4 Nitrosomonadales sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111 Bacteria 1MU5M@1224,2KM76@206350,2VHM6@28216,COG1053@1,COG1053@2 NA|NA|NA C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily HFDCGJPN_01327 583345.Mmol_0760 1.8e-106 392.1 Nitrosomonadales sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Bacteria 1MVHS@1224,2KNHF@206350,2VIKC@28216,COG0479@1,COG0479@2 NA|NA|NA C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family HFDCGJPN_01328 1387312.BAUS01000012_gene1967 7e-11 73.2 Nitrosomonadales sdhE GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 ko:K00240,ko:K09159 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 1N7P4@1224,2KN8Y@206350,2VY7W@28216,COG2938@1,COG2938@2 NA|NA|NA S Flavinator of succinate dehydrogenase HFDCGJPN_01329 1132855.KB913035_gene2044 2.1e-176 625.2 Nitrosomonadales 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1PCZW@1224,2KME9@206350,2W07M@28216,COG2301@1,COG2301@2 NA|NA|NA G HpcH/HpaI aldolase/citrate lyase family HFDCGJPN_01330 395494.Galf_0009 6.6e-253 879.8 Betaproteobacteria 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MUF5@1224,2VJJS@28216,COG0365@1,COG0365@2 NA|NA|NA I PFAM AMP-dependent synthetase and ligase HFDCGJPN_01332 1236959.BAMT01000010_gene3302 4e-33 147.5 Nitrosomonadales ko:K07394 ko00000 Bacteria 1RD3H@1224,2KN1V@206350,2VV8V@28216,COG3751@1,COG3751@2 NA|NA|NA O Prolyl 4-hydroxylase alpha subunit homologues. HFDCGJPN_01333 582744.Msip34_0689 8.3e-175 620.2 Nitrosomonadales 4.1.1.86 ko:K13745 ko00260,ko01120,map00260,map01120 R07650 RC00299 ko00000,ko00001,ko01000 Bacteria 1MWUX@1224,2KNKS@206350,2VIUF@28216,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain HFDCGJPN_01334 583345.Mmol_1590 3e-81 308.5 Nitrosomonadales yeeZ 1.5.5.1 ko:K00311 ko00000,ko01000 Bacteria 1MWVJ@1224,2KMJB@206350,2VJ3T@28216,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family HFDCGJPN_01335 582744.Msip34_0687 4.7e-73 280.8 Nitrosomonadales nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1RCX7@1224,2KMMQ@206350,2VRU5@28216,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain HFDCGJPN_01336 582744.Msip34_0685 1.3e-31 142.1 Nitrosomonadales Bacteria 1N7ID@1224,2BW9S@1,2KN36@206350,2VVR9@28216,32Z6F@2 NA|NA|NA S Protein of unknown function (DUF2818) HFDCGJPN_01337 582744.Msip34_0684 1.4e-198 699.1 Nitrosomonadales nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MV56@1224,2KM9N@206350,2VHWX@28216,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01338 582744.Msip34_0683 3.3e-235 820.8 Nitrosomonadales nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MV7V@1224,2KM01@206350,2VIAX@28216,COG1008@1,COG1008@2 NA|NA|NA C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M HFDCGJPN_01339 582744.Msip34_0682 0.0 1107.4 Nitrosomonadales nuoL 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MW2M@1224,2KKKI@206350,2VJ2J@28216,COG1009@1,COG1009@2 NA|NA|NA CP TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L HFDCGJPN_01340 583345.Mmol_1596 5.7e-41 173.3 Nitrosomonadales nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1RH0S@1224,2KMXI@206350,2VSDV@28216,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01341 582744.Msip34_0680 2.4e-89 335.1 Nitrosomonadales nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MWJV@1224,2KKQS@206350,2VJ4G@28216,COG0839@1,COG0839@2 NA|NA|NA C Belongs to the complex I subunit 6 family HFDCGJPN_01342 582744.Msip34_0679 1.7e-71 275.4 Nitrosomonadales nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 ko:K00338,ko:K03941 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 1MV90@1224,2KM6I@206350,2VIQP@28216,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01343 582744.Msip34_0678 1.2e-167 595.9 Nitrosomonadales nuoH GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MU2R@1224,2KM74@206350,2VHD0@28216,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone HFDCGJPN_01344 582744.Msip34_0677 0.0 1345.5 Nitrosomonadales nuoG 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1P8MN@1224,2KKUM@206350,2VJYV@28216,COG1034@1,COG1034@2 NA|NA|NA C TIGRFAM NADH-quinone oxidoreductase, chain G HFDCGJPN_01345 1236959.BAMT01000010_gene3269 1.2e-228 798.9 Nitrosomonadales nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MV8F@1224,2KMA3@206350,2VJJ1@28216,COG1894@1,COG1894@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain HFDCGJPN_01346 582744.Msip34_0675 2.5e-72 278.1 Nitrosomonadales nuoE 1.6.5.3,1.6.99.3 ko:K00334,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 1MWS2@1224,2KMP6@206350,2VQD9@28216,COG1905@1,COG1905@2 NA|NA|NA C TIGRFAM NADH-quinone oxidoreductase, E subunit HFDCGJPN_01347 582744.Msip34_0674 1.7e-232 811.6 Nitrosomonadales nuoD GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MVIN@1224,2KMAZ@206350,2VHEC@28216,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01348 1236959.BAMT01000010_gene3266 1e-86 326.2 Nitrosomonadales nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MX4B@1224,2KKBU@206350,2VHHV@28216,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01349 582744.Msip34_0672 3.3e-88 330.9 Nitrosomonadales nuoB GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1MUI2@1224,2KKS7@206350,2VIWK@28216,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01350 265072.Mfla_2061 3.6e-55 220.7 Nitrosomonadales nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 1RGUT@1224,2KMRP@206350,2VSI3@28216,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient HFDCGJPN_01352 582744.Msip34_0670 1e-30 139.8 Nitrosomonadales secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1N8MF@1224,2KN4I@206350,2VU0P@28216,COG1314@1,COG1314@2 NA|NA|NA U PFAM Preprotein translocase SecG subunit HFDCGJPN_01353 265072.Mfla_2064 4e-104 384.4 Nitrosomonadales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4715 Bacteria 1MWK5@1224,2KKI7@206350,2VIRP@28216,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) HFDCGJPN_01354 582744.Msip34_0668 9.7e-223 779.6 Nitrosomonadales recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1MU1M@1224,2KM81@206350,2VIGF@28216,COG0608@1,COG0608@2 NA|NA|NA L phosphoesterase RecJ domain protein HFDCGJPN_01355 1236959.BAMT01000010_gene3260 3.3e-25 122.5 Nitrosomonadales rpfE Bacteria 1R59K@1224,2KMWW@206350,2VKW9@28216,COG4255@1,COG4255@2 NA|NA|NA S protein conserved in bacteria HFDCGJPN_01356 265072.Mfla_2067 3.8e-49 201.1 Nitrosomonadales sixA ko:K08296 ko00000,ko01000 Bacteria 1RIVH@1224,2KN7I@206350,2VSSQ@28216,COG2062@1,COG2062@2 NA|NA|NA T Phosphoglycerate mutase family HFDCGJPN_01357 582744.Msip34_0665 5.6e-91 340.5 Nitrosomonadales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 1QBJX@1224,2KMPQ@206350,2VJNI@28216,COG1192@1,COG1192@2 NA|NA|NA D ATPase MipZ HFDCGJPN_01358 582744.Msip34_0664 8.4e-78 297.4 Nitrosomonadales 3.6.1.25,4.6.1.1 ko:K01768,ko:K18446 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1MY43@1224,2KMUV@206350,2VM3G@28216,COG3025@1,COG3025@2 NA|NA|NA S CYTH HFDCGJPN_01359 1101195.Meth11DRAFT_1764 3.7e-27 128.6 Nitrosomonadales Bacteria 1MVWD@1224,2KMT7@206350,2VTZ2@28216,COG3134@1,COG3134@2 NA|NA|NA S PFAM 17 kDa surface antigen HFDCGJPN_01360 666681.M301_1863 4.9e-76 291.6 Bacteria Bacteria COG1357@1,COG1357@2 NA|NA|NA S protein homooligomerization HFDCGJPN_01361 582744.Msip34_0661 4.2e-89 334.3 Nitrosomonadales nnr ko:K01420,ko:K10716 ko00000,ko02000,ko03000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 1R6BV@1224,2KM08@206350,2VN3A@28216,COG0664@1,COG0664@2 NA|NA|NA K Bacterial regulatory proteins, crp family HFDCGJPN_01362 1101195.Meth11DRAFT_1773 0.0 1667.9 Nitrosomonadales aceE GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJN746.PP_0339,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124 Bacteria 1MV21@1224,2KKET@206350,2VIAH@28216,COG2609@1,COG2609@2 NA|NA|NA C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) HFDCGJPN_01364 207954.MED92_14048 7.3e-07 60.8 Gammaproteobacteria Bacteria 1P4R3@1224,1SWE5@1236,2DD1C@1,2ZG4U@2 NA|NA|NA HFDCGJPN_01366 666681.M301_2472 8.6e-23 112.5 Nitrosomonadales Bacteria 1QCTI@1224,2B3T2@1,2KNXY@206350,2W84P@28216,31WGS@2 NA|NA|NA HFDCGJPN_01367 666681.M301_1007 1.8e-32 147.1 Nitrosomonadales fliK ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1N7XT@1224,2KN5E@206350,2VU2D@28216,COG3144@1,COG3144@2 NA|NA|NA N PFAM Flagellar hook-length control protein HFDCGJPN_01368 582744.Msip34_0760 3.1e-27 128.3 Nitrosomonadales fliJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1N4IX@1224,2KP9D@206350,2VUIK@28216,COG2882@1,COG2882@2 NA|NA|NA N Flagellar FliJ protein HFDCGJPN_01369 265072.Mfla_1975 2.5e-208 731.5 Nitrosomonadales fliI GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.14 ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1MUH6@1224,2KMB1@206350,2VHQ5@28216,COG1157@1,COG1157@2 NA|NA|NA NU ATPase FliI YscN family HFDCGJPN_01370 666681.M301_1004 1.3e-52 213.0 Nitrosomonadales fliH ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1NMQE@1224,2KMPF@206350,2VSQ0@28216,COG1317@1,COG1317@2 NA|NA|NA N PFAM Flagellar assembly protein FliH HFDCGJPN_01371 1101195.Meth11DRAFT_1558 2.1e-145 521.9 Nitrosomonadales fliG GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0046982,GO:0046983,GO:0048870,GO:0051179,GO:0051674,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0071978,GO:0097588 ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 Bacteria 1MV9X@1224,2KKH9@206350,2VI19@28216,COG1536@1,COG1536@2 NA|NA|NA N TIGRFAM flagellar motor switch protein FliG HFDCGJPN_01372 582744.Msip34_0756 1.4e-202 712.6 Nitrosomonadales fliF ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1MUQR@1224,2KKKW@206350,2VI9M@28216,COG1766@1,COG1766@2 NA|NA|NA N The M ring may be actively involved in energy transduction HFDCGJPN_01373 582744.Msip34_0755 2.3e-36 158.3 Nitrosomonadales fliE ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1N6RZ@1224,2KMYP@206350,2VVQF@28216,COG1677@1,COG1677@2 NA|NA|NA N PFAM flagellar hook-basal body complex protein FliE HFDCGJPN_01374 265072.Mfla_1980 9.6e-32 142.5 Nitrosomonadales flhB2 ko:K04061 ko00000,ko02044 Bacteria 1N7F1@1224,2KN3H@206350,2VTYF@28216,COG2257@1,COG2257@2 NA|NA|NA N FlhB HrpN YscU SpaS Family HFDCGJPN_01375 666681.M301_0999 1.5e-53 216.9 Nitrosomonadales fliK1 ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1N7CY@1224,2KPB6@206350,2WGIW@28216,COG3144@1,COG3144@2 NA|NA|NA N Flagellar hook-length control protein FliK HFDCGJPN_01376 582744.Msip34_0752 1.5e-20 105.5 Nitrosomonadales fliT ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1N9EZ@1224,2E53Z@1,2KN9Y@206350,2VWTY@28216,32ZWZ@2 NA|NA|NA N Flagellar protein FliT HFDCGJPN_01377 583345.Mmol_0922 8.5e-41 173.3 Nitrosomonadales fliS GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MZ3G@1224,2KN3I@206350,2VU2S@28216,COG1516@1,COG1516@2 NA|NA|NA N PFAM flagellar protein FliS HFDCGJPN_01378 582744.Msip34_0750 4.5e-163 581.6 Nitrosomonadales fliD GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 Bacteria 1MUVP@1224,2KKHJ@206350,2VHMK@28216,COG1345@1,COG1345@2 NA|NA|NA N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end HFDCGJPN_01379 1101195.Meth11DRAFT_1017 1.3e-23 115.9 Nitrosomonadales flaG ko:K06603 ko00000,ko02035 Bacteria 1NH9T@1224,2KN7B@206350,2VWJ2@28216,COG1334@1,COG1334@2 NA|NA|NA N FlaG protein HFDCGJPN_01380 1165096.ARWF01000001_gene937 1.2e-104 386.3 Nitrosomonadales fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Bacteria 1MV1N@1224,2KNKW@206350,2VJTA@28216,COG1344@1,COG1344@2 NA|NA|NA N Bacterial flagellin C-terminal helical region HFDCGJPN_01381 582744.Msip34_0746 1.1e-78 299.7 Nitrosomonadales ko:K02282,ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 Bacteria 1MWGM@1224,2KKNB@206350,2VQ9H@28216,COG2197@1,COG2197@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_01382 582744.Msip34_0745 5.2e-105 387.9 Nitrosomonadales 2.7.13.3 ko:K07675 ko02020,map02020 M00473 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWPN@1224,2KKYC@206350,2VJV5@28216,COG4585@1,COG4585@2 NA|NA|NA T histidine kinase dimerisation and phosphoacceptor region HFDCGJPN_01383 1101195.Meth11DRAFT_1519 1.1e-34 152.5 Nitrosomonadales flhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02403 ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040 ko00000,ko00001,ko02035 Bacteria 1N25K@1224,2AX91@1,2KMYF@206350,2VSYQ@28216,31P80@2 NA|NA|NA N Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways HFDCGJPN_01384 1502770.JQMG01000001_gene1862 1.8e-77 295.4 Nitrosomonadales flhC GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051302,GO:0051782,GO:0065007,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02402 ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040 ko00000,ko00001,ko02035 Bacteria 1N7I6@1224,2DBG4@1,2KKT9@206350,2VQ2P@28216,2Z927@2 NA|NA|NA N Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways HFDCGJPN_01385 666681.M301_1691 1.1e-69 270.0 Nitrosomonadales 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1MYRV@1224,2KMTK@206350,2VT3S@28216,COG2890@1,COG2890@2 NA|NA|NA J protein-(glutamine-N5) methyltransferase activity HFDCGJPN_01386 864073.HFRIS_010359 1.3e-130 472.6 Oxalobacteraceae motA ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1MXK3@1224,2VHPX@28216,473RR@75682,COG1291@1,COG1291@2 NA|NA|NA N MotA/TolQ/ExbB proton channel family HFDCGJPN_01387 1175306.GWL_23300 1e-117 429.9 Oxalobacteraceae motB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101 ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 1MW1Y@1224,2VHMJ@28216,472EQ@75682,COG1360@1,COG1360@2 NA|NA|NA N Membrane MotB of proton-channel complex MotA/MotB HFDCGJPN_01388 666681.M301_1688 4.9e-65 254.2 Bacteria ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria COG0840@1,COG0840@2 NA|NA|NA NT transmembrane signaling receptor activity HFDCGJPN_01389 583345.Mmol_1259 2.5e-59 234.6 Nitrosomonadales Bacteria 1RHDD@1224,2KMTB@206350,2VSDT@28216,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_01390 666681.M301_1686 1.5e-303 1048.5 Nitrosomonadales cheA GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0019904,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 ko:K02487,ko:K03407,ko:K06596 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1MUAG@1224,2KM67@206350,2VI5B@28216,COG0643@1,COG0643@2,COG2198@1,COG2198@2 NA|NA|NA NT Signal transducing histidine kinase, homodimeric HFDCGJPN_01391 582744.Msip34_0812 2.3e-63 248.4 Nitrosomonadales cheW ko:K02659,ko:K03408 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035,ko02044 Bacteria 1RD1W@1224,2KMNJ@206350,2VR41@28216,COG0835@1,COG0835@2 NA|NA|NA NT PFAM CheW domain protein HFDCGJPN_01392 1165096.ARWF01000001_gene883 1e-216 760.4 Nitrosomonadales mcpY ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2KMF1@206350,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA T chemotaxis sensory transducer HFDCGJPN_01393 1101195.Meth11DRAFT_1510 1.2e-129 470.3 Nitrosomonadales mcpY ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,2KMF1@206350,2VGZ8@28216,COG0840@1,COG0840@2 NA|NA|NA T chemotaxis sensory transducer HFDCGJPN_01394 265072.Mfla_0214 1.5e-98 365.9 Nitrosomonadales pilR ko:K02667 ko02020,map02020 M00501 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 1MU0N@1224,2KM7S@206350,2VHSB@28216,COG2204@1,COG2204@2 NA|NA|NA T PFAM sigma-54 factor interaction domain-containing protein HFDCGJPN_01395 582744.Msip34_0229 6.4e-142 510.4 Nitrosomonadales ko:K07301 ko00000,ko02000 2.A.19.5 Bacteria 1PMXR@1224,2KM61@206350,2VNME@28216,COG0530@1,COG0530@2 NA|NA|NA P PFAM sodium calcium exchanger HFDCGJPN_01396 582744.Msip34_0228 3e-69 268.1 Nitrosomonadales ampD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K03806 ko00000,ko01000,ko01011 iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Bacteria 1RDHU@1224,2KMMZ@206350,2VR5A@28216,COG3023@1,COG3023@2 NA|NA|NA V PFAM N-acetylmuramoyl-L-alanine amidase HFDCGJPN_01397 265072.Mfla_0212 2.2e-114 419.1 Nitrosomonadales Bacteria 1MXGH@1224,2KM1N@206350,2VIDH@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_01398 265072.Mfla_0211 0.0 1413.3 Nitrosomonadales acrD4 ko:K03296 ko00000 2.A.6.2 Bacteria 1MU48@1224,2KM6C@206350,2VHFI@28216,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family HFDCGJPN_01399 296591.Bpro_2306 7.9e-46 189.9 Comamonadaceae Bacteria 1MZMZ@1224,2VV6G@28216,4AFCR@80864,COG5478@1,COG5478@2 NA|NA|NA S Low affinity iron permease HFDCGJPN_01400 720554.Clocl_0922 3.4e-07 61.6 Ruminococcaceae Bacteria 1W5NA@1239,255SP@186801,2C0NX@1,2ZGH9@2,3WQP2@541000 NA|NA|NA HFDCGJPN_01401 1165096.ARWF01000001_gene1313 1.7e-72 278.9 Nitrosomonadales Bacteria 1RH4M@1224,2KP7Z@206350,2W4KZ@28216,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain HFDCGJPN_01402 1288494.EBAPG3_10990 3.7e-163 581.3 Nitrosomonadales Bacteria 1MU0Q@1224,2VJ87@28216,37294@32003,COG1301@1,COG1301@2 NA|NA|NA U Sodium:dicarboxylate symporter family HFDCGJPN_01403 582744.Msip34_0224 9.7e-186 656.4 Nitrosomonadales sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1MV2Q@1224,2KKKZ@206350,2VI1D@28216,COG0144@1,COG0144@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family HFDCGJPN_01404 1236959.BAMT01000006_gene388 4.5e-58 231.9 Nitrosomonadales 3.1.26.12 ko:K03749,ko:K08300,ko:K09859 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 1RCIU@1224,2KMRI@206350,2WHQJ@28216,COG3147@1,COG3147@2 NA|NA|NA S Protein of unknown function (DUF3108) HFDCGJPN_01405 582744.Msip34_0222 1.9e-81 308.9 Nitrosomonadales bcsB ko:K08086,ko:K20541 ko00000,ko02000 4.D.3.1.6 Bacteria 1N3SZ@1224,2KMWK@206350,2VU3V@28216,COG3170@1,COG3170@2 NA|NA|NA NU Protein of unknown function (DUF3108) HFDCGJPN_01406 582744.Msip34_0221 4.9e-172 610.5 Nitrosomonadales purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1MURG@1224,2KM3Y@206350,2VHJT@28216,COG0150@1,COG0150@2 NA|NA|NA F PFAM AIR synthase related protein HFDCGJPN_01407 582744.Msip34_0220 2.1e-117 429.1 Nitrosomonadales perM 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0B@1224,2KMHK@206350,2VHDW@28216,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter HFDCGJPN_01408 582744.Msip34_0219 4.9e-79 300.8 Nitrosomonadales hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 ko:K02313,ko:K10763 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1MVW6@1224,2KKKA@206350,2VSFD@28216,COG0593@1,COG0593@2 NA|NA|NA L TIGRFAM DnaA regulatory inactivator Hda HFDCGJPN_01409 159087.Daro_2916 5.2e-27 127.5 Betaproteobacteria ko:K08998 ko00000 Bacteria 1Q3VC@1224,2VXQF@28216,COG0759@1,COG0759@2 NA|NA|NA S Haemolytic HFDCGJPN_01411 582744.Msip34_0362 8.5e-21 105.5 Nitrosomonadales ybdD Bacteria 1NQ41@1224,2KN8N@206350,2WFEQ@28216,COG2879@1,COG2879@2 NA|NA|NA S Selenoprotein, putative HFDCGJPN_01412 582744.Msip34_0361 1.5e-108 399.1 Nitrosomonadales cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K06200 ko00000 Bacteria 1MWF9@1224,2KM50@206350,2VK59@28216,COG1966@1,COG1966@2 NA|NA|NA T PFAM Carbon starvation protein CstA HFDCGJPN_01413 582744.Msip34_1843 1.4e-126 459.1 Nitrosomonadales suhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2538,iPC815.YPO2899 Bacteria 1MUQT@1224,2KKRI@206350,2VIXG@28216,COG0483@1,COG0483@2 NA|NA|NA G PFAM Inositol monophosphatase HFDCGJPN_01414 266835.14028127 8.6e-42 177.6 Alphaproteobacteria Bacteria 1NUAR@1224,2ECNY@1,2UPJ0@28211,336KQ@2 NA|NA|NA HFDCGJPN_01416 582744.Msip34_0031 2.1e-59 235.3 Nitrosomonadales hemY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02498 ko00000 Bacteria 1MU7A@1224,2KN82@206350,2VK6P@28216,COG3071@1,COG3071@2 NA|NA|NA H PFAM HemY domain protein HFDCGJPN_01418 261292.Nit79A3_1528 2.2e-129 468.8 Nitrosomonadales lspL 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 R01385 RC00289 ko00000,ko00001,ko01000 Bacteria 1MU7J@1224,2VI0M@28216,372R4@32003,COG0451@1,COG0451@2 NA|NA|NA M Polysaccharide biosynthesis protein HFDCGJPN_01419 1123354.AUDR01000013_gene536 2.1e-109 402.9 Betaproteobacteria arnT_1 Bacteria 1N6KA@1224,2VWBM@28216,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase HFDCGJPN_01420 582744.Msip34_2581 1.3e-96 359.8 Nitrosomonadales tonB3 ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1MUMT@1224,2KMED@206350,2VKSW@28216,COG0810@1,COG0810@2 NA|NA|NA M TIGRFAM TonB family HFDCGJPN_01421 582744.Msip34_2580 1.2e-41 175.6 Nitrosomonadales fdx Bacteria 1MZR4@1224,2KMYE@206350,2VTY1@28216,COG3411@1,COG3411@2 NA|NA|NA C Ferredoxin HFDCGJPN_01422 582744.Msip34_2579 4e-53 214.2 Nitrosomonadales hit Bacteria 1MZVD@1224,2KMRM@206350,2VU7S@28216,COG0537@1,COG0537@2 NA|NA|NA FG PFAM histidine triad (HIT) protein HFDCGJPN_01423 1101195.Meth11DRAFT_2577 2.3e-20 104.4 Nitrosomonadales Bacteria 1PBBE@1224,28Y2W@1,2KNYJ@206350,2W609@28216,2ZJYF@2 NA|NA|NA HFDCGJPN_01424 583345.Mmol_0789 5.1e-190 671.0 Nitrosomonadales 2.7.7.65 ko:K13590 ko04112,map04112 ko00000,ko00001,ko01000 Bacteria 1MXAW@1224,2KKRX@206350,2VK79@28216,COG2199@1,COG3706@2 NA|NA|NA T PFAM GGDEF domain containing protein HFDCGJPN_01425 666681.M301_1566 1.2e-78 299.7 Nitrosomonadales rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 ko:K00851,ko:K00852,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01051,R01056,R01737,R02750 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 iJN678.rpiA Bacteria 1MVGR@1224,2KM2E@206350,2W26Q@28216,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate HFDCGJPN_01426 697282.Mettu_3538 1.4e-26 125.2 Methylococcales entS Bacteria 1QTX0@1224,1T1Q8@1236,1XEWU@135618,COG0477@1,COG2814@2 NA|NA|NA EGP Transmembrane secretion effector HFDCGJPN_01427 582744.Msip34_2797 1.7e-185 655.6 Nitrosomonadales dnaQ GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 ko:K02342,ko:K03703,ko:K03763,ko:K05984 ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MV8Z@1224,2KKQB@206350,2VK3W@28216,COG0322@1,COG0322@2,COG0847@1,COG0847@2 NA|NA|NA L GIY-YIG type nucleases (URI domain) HFDCGJPN_01428 582744.Msip34_0726 2.9e-189 668.3 Nitrosomonadales suv3 3.6.4.13 ko:K17675 ko00000,ko01000,ko03029 Bacteria 1MVD6@1224,2KKRH@206350,2VKPN@28216,COG4581@1,COG4581@2 NA|NA|NA L PFAM helicase domain protein HFDCGJPN_01429 1163617.SCD_n02366 5.9e-106 390.6 Betaproteobacteria 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0V@1224,2VIX0@28216,COG2833@1,COG2833@2 NA|NA|NA S protein conserved in bacteria HFDCGJPN_01430 265072.Mfla_0845 1e-56 226.5 Bacteria ko:K07000 ko00000 Bacteria COG3150@1,COG3150@2 NA|NA|NA G esterase HFDCGJPN_01432 1123392.AQWL01000007_gene873 5.8e-138 497.7 Hydrogenophilales ko:K06990,ko:K09141 ko00000,ko04812 Bacteria 1KS3P@119069,1MXK5@1224,2VKXP@28216,COG1355@1,COG1355@2,COG2078@1,COG2078@2 NA|NA|NA S Memo-like protein HFDCGJPN_01433 1132855.KB913035_gene192 4.3e-29 134.0 Nitrosomonadales mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUD4@1224,2KKYG@206350,2VH21@28216,COG1194@1,COG1194@2 NA|NA|NA L TIGRFAM A G-specific adenine glycosylase HFDCGJPN_01434 582744.Msip34_1546 8.4e-137 493.0 Nitrosomonadales trpB GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUS8@1224,2KKB6@206350,2VHV3@28216,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine HFDCGJPN_01435 582744.Msip34_1545 4e-110 404.4 Nitrosomonadales trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXJV@1224,2KMAC@206350,2VI78@28216,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate HFDCGJPN_01436 582744.Msip34_1544 4.9e-138 497.3 Nitrosomonadales accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 1MW8G@1224,2KME6@206350,2VHEQ@28216,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA HFDCGJPN_01437 265072.Mfla_1695 1.9e-133 482.6 Nitrosomonadales folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2475,iJN746.PP_1997,iSDY_1059.SDY_2514 Bacteria 1MVCH@1224,2KKX6@206350,2VI0H@28216,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family HFDCGJPN_01438 265072.Mfla_1694 4.3e-40 171.8 Nitrosomonadales dedD ko:K02520,ko:K03749,ko:K06204,ko:K16291 ko02026,map02026 ko00000,ko00001,ko01002,ko01011,ko03000,ko03009,ko03012,ko03021,ko03029 Bacteria 1R7IV@1224,2KN62@206350,2VPE1@28216,COG3147@1,COG3147@2 NA|NA|NA S Sporulation related domain HFDCGJPN_01439 582744.Msip34_1541 4.7e-61 240.7 Nitrosomonadales cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1NF4G@1224,2KMQW@206350,2VUM6@28216,COG1286@1,COG1286@2 NA|NA|NA S PFAM Colicin V production protein HFDCGJPN_01440 582744.Msip34_1540 3.5e-272 943.7 Nitrosomonadales purF GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125 Bacteria 1MU0V@1224,2KKZ4@206350,2VJM1@28216,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine HFDCGJPN_01441 582744.Msip34_1539 1.6e-197 695.3 Nitrosomonadales metZ GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0391 Bacteria 1MU57@1224,2KM6H@206350,2WGGJ@28216,COG0626@1,COG0626@2 NA|NA|NA E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide HFDCGJPN_01442 1236959.BAMT01000001_gene1434 8.7e-102 376.3 Nitrosomonadales ahpC 1.11.1.15 ko:K03386,ko:K20011 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1MWPY@1224,2KNKQ@206350,2VI7T@28216,COG0450@1,COG0450@2 NA|NA|NA O C-terminal domain of 1-Cys peroxiredoxin HFDCGJPN_01443 582744.Msip34_1535 0.0 1560.4 Nitrosomonadales gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 1MUGG@1224,2KM6T@206350,2VJ5Q@28216,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner HFDCGJPN_01444 582744.Msip34_1534 1.9e-168 598.6 Nitrosomonadales serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MUB5@1224,2KKVE@206350,2VH5M@28216,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine HFDCGJPN_01445 582744.Msip34_1533 7.3e-152 543.5 Nitrosomonadales pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,4.2.1.91,5.4.99.5 ko:K00661,ko:K01713,ko:K04092,ko:K04093,ko:K04516,ko:K04518,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2667 Bacteria 1MU60@1224,2KKEH@206350,2VJEV@28216,COG0077@1,COG0077@2,COG1605@1,COG1605@2 NA|NA|NA E amino acid-binding ACT domain protein HFDCGJPN_01446 582744.Msip34_1532 2.2e-122 445.7 Nitrosomonadales Bacteria 1QTQM@1224,2KNPY@206350,2W1IR@28216,COG2199@1,COG2199@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_01450 582744.Msip34_2543 1.6e-92 345.5 Nitrosomonadales lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 1MVRD@1224,2KKIJ@206350,2VIFE@28216,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives HFDCGJPN_01451 666681.M301_2479 4e-60 237.7 Nitrosomonadales arsC2 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1MWYQ@1224,2KMYY@206350,2VI3V@28216,COG0394@1,COG0394@2 NA|NA|NA T PFAM Protein-tyrosine phosphatase, low molecular weight HFDCGJPN_01452 305700.B447_04247 3.2e-23 114.0 Rhodocyclales Bacteria 1N728@1224,2KXBY@206389,2VWXC@28216,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin domain HFDCGJPN_01453 1221522.B723_11270 2.4e-139 501.9 Gammaproteobacteria ko:K07089 ko00000 Bacteria 1MUN8@1224,1RR9N@1236,COG0701@1,COG0701@2 NA|NA|NA S permease HFDCGJPN_01454 1297863.APJF01000010_gene3119 1.1e-43 183.0 Bradyrhizobiaceae cadI GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1RHIV@1224,2TR4K@28211,3JY40@41294,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase HFDCGJPN_01455 595536.ADVE02000001_gene2429 9.5e-24 116.3 Methylocystaceae cadC 1.20.4.1 ko:K03741,ko:K03892 ko00000,ko01000,ko03000 Bacteria 1MZAU@1224,2U9NV@28211,36YSF@31993,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor HFDCGJPN_01456 1236959.BAMT01000002_gene1964 8.1e-41 174.1 Nitrosomonadales Bacteria 1N4IH@1224,2KP7N@206350,2VU70@28216,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon HFDCGJPN_01457 1502770.JQMG01000001_gene2393 1e-82 314.3 Betaproteobacteria Bacteria 1RM4A@1224,2B14X@1,2VT75@28216,31TIS@2 NA|NA|NA HFDCGJPN_01467 666681.M301_0173 3.6e-79 301.2 Nitrosomonadales cobO GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008817,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019250,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 ko:K16092,ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.14.3 iAF1260.b1270,iB21_1397.B21_01256,iBWG_1329.BWG_1099,iECABU_c1320.ECABU_c15500,iECBD_1354.ECBD_2352,iECB_1328.ECB_01246,iECDH10B_1368.ECDH10B_1385,iECDH1ME8569_1439.ECDH1ME8569_1209,iECD_1391.ECD_01246,iECIAI1_1343.ECIAI1_1288,iECO111_1330.ECO111_1649,iECO26_1355.ECO26_1834,iETEC_1333.ETEC_1372,iEcDH1_1363.EcDH1_2379,iEcHS_1320.EcHS_A1379,iJO1366.b1270,iJR904.b1270,iLF82_1304.LF82_0253,iNRG857_1313.NRG857_06515,iUMNK88_1353.UMNK88_1599,iY75_1357.Y75_RS06640,iYL1228.KPN_01266,ic_1306.c1735 Bacteria 1MUN6@1224,2KMMV@206350,2VM7I@28216,COG2109@1,COG2109@2 NA|NA|NA H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids HFDCGJPN_01468 666681.M301_0174 7.7e-60 236.9 Nitrosomonadales Bacteria 1RM6G@1224,2ARZT@1,2KNS2@206350,2VT5G@28216,31HBY@2 NA|NA|NA HFDCGJPN_01469 666681.M301_0175 7.7e-165 587.4 Nitrosomonadales btuB GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 ko:K16092 ko00000,ko02000 1.B.14.3 iECB_1328.ECB_03851,iECP_1309.ECP_4183,iSF_1195.SF4048,iS_1188.S3696 Bacteria 1MW63@1224,2KKSU@206350,2VH64@28216,COG4206@1,COG4206@2 NA|NA|NA H TonB dependent receptor HFDCGJPN_01470 265072.Mfla_0123 1.6e-14 85.1 Nitrosomonadales Bacteria 1QA1T@1224,2APM6@1,2KNCI@206350,2VYY3@28216,31EQI@2 NA|NA|NA HFDCGJPN_01471 582744.Msip34_0158 1.3e-40 172.2 Nitrosomonadales zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 1N6YN@1224,2KP3R@206350,2VUY2@28216,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division HFDCGJPN_01472 582744.Msip34_0159 4.6e-58 230.3 Nitrosomonadales ko:K09966 ko00000 Bacteria 1RH68@1224,2KMS3@206350,2VSN3@28216,COG3651@1,COG3651@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2237) HFDCGJPN_01473 582744.Msip34_0160 2.6e-74 284.6 Nitrosomonadales Bacteria 1RHRU@1224,2KKTX@206350,2VRIB@28216,COG2947@1,COG2947@2 NA|NA|NA S EVE domain HFDCGJPN_01474 582744.Msip34_0162 1.6e-74 286.6 Nitrosomonadales Bacteria 1P862@1224,2KMGK@206350,2VJRK@28216,COG3391@1,COG3391@2 NA|NA|NA S TIGRFAM 40-residue YVTN family beta-propeller repeat HFDCGJPN_01475 582744.Msip34_0163 7.7e-248 862.8 Nitrosomonadales ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 iJN678.ilvA Bacteria 1MVWJ@1224,2KKTG@206350,2VI5U@28216,COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA HFDCGJPN_01476 582744.Msip34_0164 3.3e-110 404.4 Nitrosomonadales rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVGR@1224,2KKDZ@206350,2VH27@28216,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate HFDCGJPN_01477 582744.Msip34_0165 1e-117 429.5 Nitrosomonadales phoU GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 ko:K02039 ko00000 Bacteria 1MUMI@1224,2KM7N@206350,2VI2C@28216,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake HFDCGJPN_01478 582744.Msip34_0166 5.4e-209 733.8 Nitrosomonadales ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1MV35@1224,2KMEZ@206350,2VI1K@28216,COG0248@1,COG0248@2 NA|NA|NA FP PFAM Ppx GppA phosphatase HFDCGJPN_01479 582744.Msip34_0167 0.0 1130.9 Nitrosomonadales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 1MUM3@1224,2KKXK@206350,2VHH8@28216,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) HFDCGJPN_01480 666681.M301_2731 6.8e-89 334.3 Nitrosomonadales ko:K18302 M00642 ko00000,ko00002,ko01504,ko02000 2.A.6.2,8.A.1 Bacteria 1NJDF@1224,2KM0E@206350,2VIS6@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_01481 666681.M301_2732 6.6e-76 290.4 Nitrosomonadales ttgR Bacteria 1N6R3@1224,2KMJV@206350,2VSN4@28216,COG1309@1,COG1309@2 NA|NA|NA K WHG domain HFDCGJPN_01482 857087.Metme_3255 1.4e-75 290.0 Methylococcales ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MVJA@1224,1S43R@1236,1XGFV@135618,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family HFDCGJPN_01485 582744.Msip34_1006 2.2e-70 271.9 Nitrosomonadales pgsA 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 1RCZ7@1224,2KMN8@206350,2VQI2@28216,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family HFDCGJPN_01486 1132855.KB913035_gene2030 7.5e-279 966.1 Nitrosomonadales uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1MV38@1224,2KMD9@206350,2VIM4@28216,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision HFDCGJPN_01487 1122236.KB905141_gene658 3.2e-23 113.6 Nitrosomonadales dmpI 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1PTA7@1224,2KNAP@206350,2VW9V@28216,COG1942@1,COG1942@2 NA|NA|NA S Tautomerase enzyme HFDCGJPN_01488 1123392.AQWL01000004_gene2579 2.4e-78 298.5 Hydrogenophilales udgB GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1KSM7@119069,1MW91@1224,2VQ3T@28216,COG1573@1,COG1573@2 NA|NA|NA L Uracil DNA glycosylase superfamily HFDCGJPN_01489 582744.Msip34_1003 3.5e-102 378.3 Nitrosomonadales zitB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 ko:K16264 ko00000,ko02000 2.A.4.1 iNRG857_1313.NRG857_03325,iPC815.YPO1129 Bacteria 1QUZ5@1224,2KMTU@206350,2WGMK@28216,COG1230@1,COG1230@2 NA|NA|NA P TIGRFAM cation diffusion facilitator family transporter HFDCGJPN_01491 582744.Msip34_1001 3.7e-56 224.6 Nitrosomonadales sodC GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 iEcolC_1368.EcolC_1983 Bacteria 1RGV4@1224,2KNB6@206350,2VSTR@28216,COG2032@1,COG2032@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems HFDCGJPN_01492 582744.Msip34_1000 3.8e-103 381.3 Nitrosomonadales rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 ko00000,ko01000,ko03009 Bacteria 1MWGA@1224,2KM86@206350,2VHM4@28216,COG2961@1,COG2961@2 NA|NA|NA S Specifically methylates the adenine in position 2030 of 23S rRNA HFDCGJPN_01493 1159870.KB907784_gene3357 1.2e-226 795.0 Alcaligenaceae Bacteria 1MUZK@1224,2VHVG@28216,3T868@506,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat HFDCGJPN_01494 582744.Msip34_0996 6.4e-120 436.8 Nitrosomonadales acnB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415 Bacteria 1MVCR@1224,2KKKN@206350,2VHT2@28216,COG1049@1,COG1049@2 NA|NA|NA C Belongs to the aconitase IPM isomerase family HFDCGJPN_01495 1236959.BAMT01000001_gene1543 1.1e-87 329.3 Nitrosomonadales orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1R9WX@1224,2KKU2@206350,2VIA2@28216,COG1949@1,COG1949@2 NA|NA|NA L 3'-to-5' exoribonuclease specific for small oligoribonucleotides HFDCGJPN_01496 265072.Mfla_1472 1.9e-174 619.0 Nitrosomonadales glgA GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 iSFV_1184.SFV_3438 Bacteria 1MUGM@1224,2KM1X@206350,2VH1G@28216,COG0297@1,COG0297@2 NA|NA|NA G Synthesizes alpha-1,4-glucan chains using ADP-glucose HFDCGJPN_01497 666681.M301_1510 3.8e-34 151.0 Nitrosomonadales crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1MZNH@1224,2KNAY@206350,2VUBZ@28216,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity HFDCGJPN_01498 583345.Mmol_1169 7.2e-91 340.5 Nitrosomonadales Bacteria 1R4ZN@1224,2KM18@206350,2VQ1P@28216,COG1639@1,COG1639@2 NA|NA|NA T PFAM Metal-dependent hydrolase HDOD HFDCGJPN_01499 582744.Msip34_1434 2e-59 235.0 Nitrosomonadales rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 ko:K01754,ko:K02990 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,ko03010,map00260,map00290,map01100,map01110,map01130,map01200,map01230,map03010 M00178,M00570 R00220,R00996 RC00418,RC02600 br01610,ko00000,ko00001,ko00002,ko01000,ko03011,ko03029 Bacteria 1RH82@1224,2KMRN@206350,2VR79@28216,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA HFDCGJPN_01500 582744.Msip34_1433 1.8e-28 131.7 Nitrosomonadales priB GO:0000228,GO:0000428,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005658,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006270,GO:0006276,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016070,GO:0018130,GO:0019438,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990077,GO:1990099,GO:1990234,GO:1990837 ko:K02686 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1N98W@1224,2KN9V@206350,2VVZ4@28216,COG2965@1,COG2965@2 NA|NA|NA L Binds single-stranded DNA at the primosome assembly site (PAS) HFDCGJPN_01501 265072.Mfla_1328 1.1e-33 148.7 Nitrosomonadales rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ8U@1224,2KN2Q@206350,2VTWT@28216,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit HFDCGJPN_01502 265072.Mfla_1329 4.1e-64 250.8 Nitrosomonadales rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RD0R@1224,2KMMX@206350,2VR40@28216,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA HFDCGJPN_01503 582744.Msip34_1429 5.8e-234 816.6 Nitrosomonadales dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1MUG9@1224,2KKWN@206350,2VIKN@28216,COG0305@1,COG0305@2 NA|NA|NA L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins HFDCGJPN_01504 582744.Msip34_1428 1e-129 469.9 Nitrosomonadales alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008784,GO:0009058,GO:0009059,GO:0009078,GO:0009079,GO:0009252,GO:0009273,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0030170,GO:0030203,GO:0030632,GO:0034645,GO:0036094,GO:0036361,GO:0040007,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iWFL_1372.ECW_m1275,iYL1228.KPN_02308 Bacteria 1MV0Q@1224,2KKE4@206350,2VIXM@28216,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids HFDCGJPN_01505 582744.Msip34_1427 1.5e-229 802.0 Nitrosomonadales radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 1MUJQ@1224,2KKFH@206350,2VH93@28216,COG1066@1,COG1066@2 NA|NA|NA L DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function HFDCGJPN_01506 312153.Pnuc_1825 1.1e-70 275.0 Burkholderiaceae Bacteria 1KGHM@119060,1MUZK@1224,2VHVG@28216,COG0457@1,COG0457@2,COG0859@1,COG0859@2 NA|NA|NA M repeat-containing protein HFDCGJPN_01507 582744.Msip34_1426 4.7e-61 241.1 Nitrosomonadales 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1REXF@1224,2KNCS@206350,2VS3D@28216,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase HFDCGJPN_01511 582744.Msip34_2109 5.2e-132 477.6 Nitrosomonadales MA20_36195 ko:K09919 ko00000 Bacteria 1MU35@1224,2KKBK@206350,2VH0Z@28216,COG3146@1,COG3146@2 NA|NA|NA S Peptidogalycan biosysnthesis/recognition HFDCGJPN_01512 582744.Msip34_2110 9.8e-11 72.4 Nitrosomonadales osmB ko:K04062 ko00000 Bacteria 1NPIC@1224,2C5IZ@1,2KNAF@206350,2VVUV@28216,33B4P@2 NA|NA|NA M Glycine zipper 2TM domain HFDCGJPN_01513 582744.Msip34_2111 2.7e-24 118.6 Nitrosomonadales Bacteria 1P5Q9@1224,2KN9J@206350,2VXYA@28216,COG5126@1,COG5126@2 NA|NA|NA DTZ Ca2 -binding protein (EF-Hand superfamily HFDCGJPN_01514 265072.Mfla_0654 2.3e-117 428.3 Nitrosomonadales Bacteria 1MY3D@1224,2KKH4@206350,2VI6B@28216,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_01515 1236959.BAMT01000004_gene830 1.2e-188 666.0 Nitrosomonadales Bacteria 1MUAK@1224,2KM7A@206350,2VJ6W@28216,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor HFDCGJPN_01516 666681.M301_2134 1.7e-193 682.2 Nitrosomonadales cysG GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.1.1.131,3.7.1.12,4.2.1.75,4.99.1.3,4.99.1.4 ko:K02302,ko:K02303,ko:K02304,ko:K03795,ko:K13541,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947,R05180,R05807,R05809,R07772 RC00003,RC00871,RC01012,RC01034,RC01293,RC01545,RC01861,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158 Bacteria 1MUI0@1224,2KKMV@206350,2VICS@28216,COG0007@1,COG0007@2,COG1648@1,COG1648@2 NA|NA|NA H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme HFDCGJPN_01518 265072.Mfla_0199 1.8e-62 245.4 Nitrosomonadales moaC 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 1RCYZ@1224,2KMT6@206350,2VR7B@28216,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) HFDCGJPN_01521 666681.M301_2408 1.4e-153 548.9 Nitrosomonadales argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 1MU17@1224,2KKS4@206350,2VIIY@28216,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily HFDCGJPN_01522 666681.M301_2409 9.9e-80 303.1 Nitrosomonadales phnX 3.1.3.23,3.11.1.1 ko:K05306,ko:K07025,ko:K19270 ko00440,ko01100,ko01120,map00440,map01100,map01120 R00747 RC00368 ko00000,ko00001,ko01000 Bacteria 1QTWD@1224,2KM8Z@206350,2VNTW@28216,COG0637@1,COG0637@2 NA|NA|NA S subfamily IA, variant 3 HFDCGJPN_01523 265072.Mfla_2257 8.3e-78 296.6 Nitrosomonadales slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K05501 ko00000,ko03000,ko03036 Bacteria 1MWF7@1224,2KKDC@206350,2VQ4C@28216,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family HFDCGJPN_01524 1158294.JOMI01000003_gene2776 6.6e-79 301.2 Bacteroidia Bacteria 2AC3P@1,2FXDA@200643,311MX@2,4PGG7@976 NA|NA|NA S FRG domain HFDCGJPN_01525 582744.Msip34_0034 2.9e-116 424.9 Nitrosomonadales hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849 Bacteria 1MU56@1224,2KKSA@206350,2VHT4@28216,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps HFDCGJPN_01526 582744.Msip34_0033 7.5e-90 337.0 Nitrosomonadales hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K02496,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0187,iSBO_1134.SBO_3815 Bacteria 1MWZD@1224,2KM8Q@206350,2VRU9@28216,COG1587@1,COG1587@2 NA|NA|NA H PFAM Uroporphyrinogen III synthase HEM4 HFDCGJPN_01527 582744.Msip34_2459 7.5e-269 932.6 Nitrosomonadales tmd 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 ko:K00123,ko:K00317,ko:K00528,ko:K09835 ko00630,ko00680,ko00906,ko01100,ko01110,ko01120,ko01200,map00630,map00680,map00906,map01100,map01110,map01120,map01200 M00097 R00519,R01588,R02511,R07512,R10159 RC00185,RC00556,RC00557,RC00732,RC01960,RC02796 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVE0@1224,2KM7C@206350,2VJ6V@28216,COG0493@1,COG0493@2,COG1902@1,COG1902@2 NA|NA|NA CE PFAM NADH flavin oxidoreductase NADH oxidase HFDCGJPN_01528 381666.H16_B0951 6e-28 130.6 Betaproteobacteria 1.14.12.17 ko:K05916 ko05132,map05132 ko00000,ko00001,ko01000 Bacteria 1QVJP@1224,2VV2W@28216,COG1017@1,COG1017@2 NA|NA|NA C Belongs to the globin family HFDCGJPN_01531 1236959.BAMT01000013_gene2989 3e-138 498.0 Nitrosomonadales hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 ko:K03665 ko00000,ko03009 Bacteria 1MUA0@1224,2KM54@206350,2VI86@28216,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis HFDCGJPN_01532 582744.Msip34_1690 6.2e-184 650.2 Nitrosomonadales hflK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 ko:K04088 M00742 ko00000,ko00002,ko01000 Bacteria 1MUM2@1224,2KKRU@206350,2VIG2@28216,COG0330@1,COG0330@2 NA|NA|NA O HflC and HflK could encode or regulate a protease HFDCGJPN_01533 265072.Mfla_1586 6.3e-109 400.6 Nitrosomonadales hflC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 ko:K04087 M00742 ko00000,ko00002,ko01000 Bacteria 1MV7R@1224,2KM4X@206350,2VI9W@28216,COG0330@1,COG0330@2 NA|NA|NA O HflC and HflK could regulate a protease HFDCGJPN_01534 582744.Msip34_1688 2.7e-14 84.0 Nitrosomonadales yjeT ko:K09937 ko00000 Bacteria 1NG9Q@1224,2KN84@206350,2VXNJ@28216,COG3242@1,COG3242@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2065) HFDCGJPN_01535 582744.Msip34_1687 2.2e-165 588.6 Nitrosomonadales hisZ 2.4.2.17,6.1.1.21 ko:K00765,ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1MWIG@1224,2KKH5@206350,2VHVX@28216,COG3705@1,COG3705@2 NA|NA|NA E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine HFDCGJPN_01536 582744.Msip34_1686 3.2e-229 800.8 Nitrosomonadales purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Bacteria 1MU5B@1224,2KM3G@206350,2VHBR@28216,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP HFDCGJPN_01537 582744.Msip34_1685 1.1e-82 312.8 Nitrosomonadales spoVFB 1.2.7.3 ko:K00176,ko:K06411 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 M00009,M00011,M00173,M00620 R01197 RC00004,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1RD5I@1224,2KMI2@206350,2VQ1A@28216,COG1036@1,COG1036@2 NA|NA|NA C PFAM Flavoprotein HFDCGJPN_01538 582744.Msip34_1684 7.9e-210 736.5 Nitrosomonadales prtA 3.2.1.23 ko:K01190,ko:K07004,ko:K13277 ko00052,ko00511,ko00600,ko01100,ko02024,map00052,map00511,map00600,map01100,map02024 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 1QY39@1224,2KPA6@206350,2WH9V@28216,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family HFDCGJPN_01539 265072.Mfla_1580 1.1e-64 253.1 Nitrosomonadales ko:K09154 ko00000 Bacteria 1RD0V@1224,2KMR7@206350,2VS9E@28216,COG2457@1,COG2457@2 NA|NA|NA S Protein of unknown function (DUF447) HFDCGJPN_01540 265072.Mfla_1579 1.7e-51 209.5 Nitrosomonadales 1.13.11.81,4.1.2.25,4.2.3.153,5.1.99.8 ko:K01633,ko:K09733 ko00680,ko00790,ko01100,map00680,map00790,map01100 M00126,M00840 R03504,R10935,R11037,R11073 RC00721,RC00943,RC01479,RC03315,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1RGX0@1224,2KP82@206350,2VX74@28216,COG1891@1,COG1891@2 NA|NA|NA S 4-HFC-P synthase HFDCGJPN_01541 582744.Msip34_1681 3.8e-119 434.9 Nitrosomonadales ompA GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 ko:K03286,ko:K03640 ko00000,ko02000 1.B.6,2.C.1.2 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 Bacteria 1N6EM@1224,2KP54@206350,2VM27@28216,COG2885@1,COG2885@2,COG3637@1,COG3637@2 NA|NA|NA M OprF membrane domain HFDCGJPN_01542 265072.Mfla_1577 1.7e-166 592.4 Nitrosomonadales mtaD 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 R09660 RC00477 ko00000,ko00001,ko01000 Bacteria 1MVPA@1224,2KKCD@206350,2VJ4R@28216,COG0402@1,COG0402@2 NA|NA|NA F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine HFDCGJPN_01543 1236959.BAMT01000013_gene3002 4.8e-99 367.5 Nitrosomonadales ubiG 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU89@1224,2KKJS@206350,2VHGP@28216,COG2227@1,COG2227@2 NA|NA|NA H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway HFDCGJPN_01544 1502770.JQMG01000001_gene2228 1.9e-78 298.9 Nitrosomonadales gph GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006040,GO:0006082,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009254,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0030203,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097172,GO:1901135,GO:1901360,GO:1901564 3.1.3.105 ko:K22292 ko00520,map00520 R11785 RC00017 ko00000,ko00001,ko01000 Bacteria 1RCXJ@1224,2KMBK@206350,2VS13@28216,COG0546@1,COG0546@2 NA|NA|NA S subfamily IA, variant 1 HFDCGJPN_01545 582744.Msip34_1677 1.4e-91 342.4 Nitrosomonadales recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1MV9Q@1224,2KKXY@206350,2VJVJ@28216,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO HFDCGJPN_01546 583345.Mmol_0905 5.2e-34 150.2 Nitrosomonadales ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 ko:K06187,ko:K09747 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1RGZD@1224,2KN4G@206350,2W37G@28216,COG0718@1,COG0718@2 NA|NA|NA L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection HFDCGJPN_01547 265072.Mfla_1572 4.5e-209 734.2 Nitrosomonadales dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MVCK@1224,2KKNZ@206350,2VIE0@28216,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity HFDCGJPN_01548 1165096.ARWF01000001_gene130 5.7e-148 530.8 Nitrosomonadales 4.6.1.2 ko:K01769 ko00230,map00230 R00434 RC00295 ko00000,ko00001,ko01000 Bacteria 1QWNC@1224,2KMIU@206350,2VHX9@28216,COG2114@1,COG2114@2 NA|NA|NA T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family HFDCGJPN_01550 265072.Mfla_2319 9.9e-137 493.0 Nitrosomonadales yceA ko:K07146 ko00000 Bacteria 1MUFV@1224,2KMBX@206350,2VIX6@28216,COG1054@1,COG1054@2 NA|NA|NA S Belongs to the UPF0176 family HFDCGJPN_01551 582744.Msip34_1218 3.1e-70 271.6 Nitrosomonadales Bacteria 1N912@1224,2E9MD@1,2KN0R@206350,2VWSF@28216,333U1@2 NA|NA|NA S Yip1 domain HFDCGJPN_01552 1101195.Meth11DRAFT_1421 2.6e-65 255.0 Nitrosomonadales btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 1RDR8@1224,2KMME@206350,2VQHV@28216,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family HFDCGJPN_01553 323261.Noc_2091 3.4e-110 405.2 Chromatiales Bacteria 1NHTY@1224,1T21B@1236,1WYKA@135613,COG0454@1,COG0456@2 NA|NA|NA K Domain of unknown function (DUF4915) HFDCGJPN_01554 666681.M301_2737 1.9e-60 239.2 Nitrosomonadales Bacteria 1MU4M@1224,2KMUH@206350,2VQKI@28216,COG3907@1,COG3907@2 NA|NA|NA S PAP2 superfamily HFDCGJPN_01555 580332.Slit_2348 5.4e-125 454.1 Nitrosomonadales srkA GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 Bacteria 1MU2Q@1224,2VI9A@28216,44V37@713636,COG2334@1,COG2334@2 NA|NA|NA H A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response HFDCGJPN_01556 857087.Metme_4433 1.4e-23 117.1 Methylococcales Bacteria 1PEPV@1224,1SFWB@1236,1XFT1@135618,COG0666@1,COG0666@2 NA|NA|NA S Ankyrin repeat HFDCGJPN_01557 3988.XP_002535236.1 7.8e-34 149.4 Eukaryota Eukaryota 2S172@2759,COG3450@1 NA|NA|NA S Protein of unknown function (DUF861) HFDCGJPN_01558 887898.HMPREF0551_1003 7.9e-21 107.5 Burkholderiaceae crp ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1K34H@119060,1RE4X@1224,2VRYB@28216,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator HFDCGJPN_01559 246200.SPO0447 7.7e-19 101.3 Bacteria Bacteria 296RU@1,2ZU0X@2 NA|NA|NA HFDCGJPN_01560 365046.Rta_34200 7.3e-10 72.4 Comamonadaceae Bacteria 1Q0ZV@1224,2AIDD@1,2W5XR@28216,318US@2,4AIRD@80864 NA|NA|NA HFDCGJPN_01561 323848.Nmul_A2168 5.4e-37 160.2 Nitrosomonadales ko:K09946 ko00000 Bacteria 1N0S6@1224,2VUA2@28216,373DS@32003,COG3422@1,COG3422@2 NA|NA|NA S Domain of unknown function (DUF1508) HFDCGJPN_01562 1165096.ARWF01000001_gene2099 9.8e-82 310.1 Betaproteobacteria ko:K07504 ko00000 Bacteria 1RFCH@1224,2VZ5Q@28216,COG2810@1,COG2810@2 NA|NA|NA V Type I restriction enzyme R protein N terminus (HSDR_N) HFDCGJPN_01563 1216976.AX27061_3189 1.1e-127 463.8 Betaproteobacteria Bacteria 1MWN5@1224,28J59@1,2VZ9K@28216,2Z915@2 NA|NA|NA HFDCGJPN_01564 666681.M301_2200 6.4e-48 198.0 Betaproteobacteria Bacteria 1NWUQ@1224,2F3QV@1,2W2UH@28216,33WHK@2 NA|NA|NA HFDCGJPN_01565 1132855.KB913035_gene2594 3.6e-156 558.1 Betaproteobacteria Bacteria 1QWQ3@1224,2DBHN@1,2VH4F@28216,2Z9BF@2 NA|NA|NA HFDCGJPN_01566 261292.Nit79A3_1998 1.2e-157 562.8 Proteobacteria intD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0008979,GO:0009009,GO:0009987,GO:0015074,GO:0016032,GO:0019042,GO:0019043,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051704,GO:0071704,GO:0075713,GO:0090304,GO:0140097,GO:1901360 Bacteria 1MWBN@1224,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family HFDCGJPN_01567 758.BBIX01000005_gene80 3.3e-15 89.7 Pasteurellales 2.7.7.7 ko:K02343,ko:K03642,ko:K13733,ko:K14195 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,ko05100,ko05150,map00230,map00240,map01100,map03030,map03430,map03440,map05100,map05150 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MU7T@1224,1RNK8@1236,1Y7E1@135625,COG2931@1,COG2931@2,COG3087@1,COG3087@2 NA|NA|NA Q COG2931 RTX toxins and related Ca2 -binding proteins HFDCGJPN_01568 582744.Msip34_2303 2.3e-109 401.7 Nitrosomonadales MA20_32445 ko:K07395 ko00000 Bacteria 1N057@1224,2KKK7@206350,2VHD7@28216,COG3484@1,COG3484@2 NA|NA|NA O PFAM 20S proteasome A and B subunits HFDCGJPN_01569 1101195.Meth11DRAFT_1164 0.0 1907.5 Nitrosomonadales MA20_16195 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0030115,GO:0030312,GO:0044464,GO:0045229,GO:0071840,GO:0071944 Bacteria 1MVAG@1224,2KKJ6@206350,2VKKZ@28216,COG1305@1,COG1305@2,COG4196@1,COG4196@2 NA|NA|NA E Putative amidoligase enzyme (DUF2126) HFDCGJPN_01572 375286.mma_0459 1.1e-39 169.5 Oxalobacteraceae ko:K07112 ko00000 Bacteria 1MZC0@1224,2VT72@28216,474IJ@75682,COG2391@1,COG2391@2 NA|NA|NA S transporter component HFDCGJPN_01573 582744.Msip34_2164 1.2e-202 712.6 Nitrosomonadales pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1MVCS@1224,2KKUQ@206350,2VHY5@28216,COG0617@1,COG0617@2 NA|NA|NA J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control HFDCGJPN_01574 582744.Msip34_2165 1.7e-63 248.8 Nitrosomonadales folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 Bacteria 1MZH8@1224,2KN0P@206350,2VSE2@28216,COG0801@1,COG0801@2 NA|NA|NA H PFAM 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HFDCGJPN_01575 582744.Msip34_2166 2.2e-95 355.1 Nitrosomonadales dgk 2.7.1.113 ko:K15518 ko00230,map00230 R01967 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1RC50@1224,2KMBR@206350,2VQ8U@28216,COG1428@1,COG1428@2 NA|NA|NA F PFAM deoxynucleoside kinase HFDCGJPN_01576 582744.Msip34_2167 1.1e-104 386.3 Nitrosomonadales panB 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU3B@1224,2KKFU@206350,2VHZ0@28216,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate HFDCGJPN_01577 582744.Msip34_2168 1.1e-102 379.8 Nitrosomonadales panC GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144 Bacteria 1MV1S@1224,2KKN9@206350,2VHF1@28216,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate HFDCGJPN_01578 582744.Msip34_2173 1.9e-57 228.4 Nitrosomonadales panD GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0010467,GO:0015939,GO:0015940,GO:0016053,GO:0016485,GO:0016540,GO:0016829,GO:0016830,GO:0016831,GO:0019538,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_0139,iYL1228.KPN_00139 Bacteria 1RI1B@1224,2KMU9@206350,2VSDU@28216,COG0853@1,COG0853@2 NA|NA|NA H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine HFDCGJPN_01579 1236959.BAMT01000004_gene759 6.9e-46 189.9 Nitrosomonadales rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1MZEF@1224,2KMSE@206350,2VRRV@28216,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation HFDCGJPN_01580 1245469.S58_53890 2.1e-07 61.6 Bradyrhizobiaceae Bacteria 1MXPM@1224,2TSB9@28211,3K6SH@41294,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily HFDCGJPN_01581 582744.Msip34_0717 0.0 1147.9 Nitrosomonadales thrS GO:0000166,GO:0000900,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004812,GO:0004829,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006435,GO:0006446,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0017076,GO:0017148,GO:0019222,GO:0019538,GO:0019752,GO:0030371,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032553,GO:0032555,GO:0032559,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045947,GO:0046483,GO:0046872,GO:0046914,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097367,GO:0106074,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iPC815.YPO2433,iSDY_1059.SDY_1814 Bacteria 1MUP2@1224,2KM0I@206350,2VHFD@28216,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) HFDCGJPN_01582 582744.Msip34_0718 3.9e-70 270.8 Nitrosomonadales infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1RDD2@1224,2KMKP@206350,2VQ19@28216,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins HFDCGJPN_01583 583345.Mmol_1586 2.1e-25 120.9 Nitrosomonadales rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1N6V4@1224,2KN5H@206350,2VVS9@28216,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family HFDCGJPN_01584 1236959.BAMT01000016_gene2805 2e-53 214.9 Nitrosomonadales rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RGU2@1224,2KMT0@206350,2VRWF@28216,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit HFDCGJPN_01585 265072.Mfla_1999 2e-164 585.1 Nitrosomonadales pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176 Bacteria 1MVD7@1224,2KM6N@206350,2VIM9@28216,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily HFDCGJPN_01588 1318628.MARLIPOL_02710 8.9e-30 136.3 Gammaproteobacteria tfoX ko:K07343 ko00000 Bacteria 1N8X8@1224,1SC6J@1236,COG3070@1,COG3070@2 NA|NA|NA K Regulator of HFDCGJPN_01589 582744.Msip34_0572 2e-138 498.8 Nitrosomonadales holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MWYT@1224,2KKVI@206350,2VIKX@28216,COG1466@1,COG1466@2 NA|NA|NA L TIGRFAM DNA polymerase III, delta subunit HFDCGJPN_01590 582744.Msip34_0573 6e-51 207.2 Nitrosomonadales lptE GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 ko:K03643 ko00000,ko02000 1.B.42.1 iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 Bacteria 1N13K@1224,2KMX8@206350,2VU54@28216,COG2980@1,COG2980@2 NA|NA|NA M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane HFDCGJPN_01591 1101195.Meth11DRAFT_0648 0.0 1536.9 Nitrosomonadales leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 Bacteria 1MV47@1224,2KKE0@206350,2VH2J@28216,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family HFDCGJPN_01592 506534.Rhein_3884 2e-11 77.0 Gammaproteobacteria ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MX3N@1224,1RQ7N@1236,COG0840@1,COG0840@2 NA|NA|NA NT chemotaxis, protein HFDCGJPN_01593 582744.Msip34_0823 1e-184 653.3 Nitrosomonadales aprD ko:K06147,ko:K06148,ko:K12536,ko:K16299 ko02010,map02010 M00328,M00571 ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.110.10,3.A.1.21 Bacteria 1NTI5@1224,2KM4N@206350,2VHSJ@28216,COG4618@1,COG4618@2 NA|NA|NA V ABC transporter HFDCGJPN_01594 909663.KI867150_gene2172 2.8e-131 475.3 Deltaproteobacteria expC Bacteria 1NJ19@1224,2WJJ7@28221,42NG7@68525,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 HFDCGJPN_01595 582744.Msip34_0908 9.6e-212 743.0 Nitrosomonadales nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU9U@1224,2KKUX@206350,2VJ8C@28216,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source HFDCGJPN_01596 1165096.ARWF01000001_gene2264 2.6e-07 63.2 Nitrosomonadales ko:K06867 ko00000 Bacteria 1RBYV@1224,2KKR1@206350,2VVSX@28216,COG0666@1,COG0666@2 NA|NA|NA S Ankyrin repeat HFDCGJPN_01597 265072.Mfla_1888 5.5e-145 520.4 Nitrosomonadales sucD GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071973,GO:0097588,GO:1901564,GO:1902494 6.2.1.5 ko:K01902,ko:K02381 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_0608 Bacteria 1MUGA@1224,2KKX8@206350,2VH1U@28216,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit HFDCGJPN_01598 582744.Msip34_0905 3e-183 647.9 Nitrosomonadales sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009361,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0042709,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iPC815.YPO1115,iUMNK88_1353.UMNK88_764 Bacteria 1MVCE@1224,2KKYP@206350,2VHBG@28216,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit HFDCGJPN_01599 582744.Msip34_0904 2.6e-115 421.8 Nitrosomonadales serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 Bacteria 1MWA3@1224,2KM78@206350,2VKZJ@28216,COG0560@1,COG0560@2 NA|NA|NA E PFAM Haloacid dehalogenase domain protein hydrolase HFDCGJPN_01600 265072.Mfla_1891 6.5e-62 243.8 Betaproteobacteria 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 1R9ZQ@1224,2VQ6F@28216,COG0652@1,COG0652@2 NA|NA|NA M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides HFDCGJPN_01601 1236959.BAMT01000001_gene1291 4.8e-37 161.4 Nitrosomonadales Bacteria 1NM2K@1224,2EM7S@1,2KMSQ@206350,2VYUH@28216,33EWW@2 NA|NA|NA HFDCGJPN_01602 580332.Slit_1246 1.8e-77 295.4 Nitrosomonadales yaeQ Bacteria 1RDR9@1224,2VR81@28216,44VRH@713636,COG4681@1,COG4681@2 NA|NA|NA S YaeQ HFDCGJPN_01603 582744.Msip34_0903 4.9e-98 364.4 Nitrosomonadales Bacteria 1QY38@1224,2KKY0@206350,2W7VM@28216,COG3386@1,COG3386@2 NA|NA|NA G SMP-30/Gluconolaconase/LRE-like region HFDCGJPN_01604 582744.Msip34_0902 1.7e-41 176.0 Nitrosomonadales Bacteria 1PJIM@1224,2BUKJ@1,2KN6G@206350,2W80F@28216,32PX3@2 NA|NA|NA HFDCGJPN_01605 582744.Msip34_0901 1e-155 556.6 Nitrosomonadales Bacteria 1RC14@1224,2KM5X@206350,2VPAW@28216,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase HFDCGJPN_01606 1165096.ARWF01000001_gene2275 2.6e-172 611.7 Nitrosomonadales 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 1N5MC@1224,2KKP3@206350,2VK35@28216,COG0446@1,COG0446@2 NA|NA|NA S PFAM Flavocytochrome c sulphide dehydrogenase, flavin-binding HFDCGJPN_01607 582744.Msip34_0899 5.4e-25 120.6 Nitrosomonadales soxE Bacteria 1NGJ1@1224,2KNB9@206350,2VVR2@28216,COG2863@1,COG2863@2 NA|NA|NA C cytochrome HFDCGJPN_01608 582744.Msip34_0898 8.3e-26 123.6 Nitrosomonadales Bacteria 1N995@1224,2KN00@206350,2VYC2@28216,COG0666@1,COG0666@2 NA|NA|NA S Ankyrin repeats (3 copies) HFDCGJPN_01609 582744.Msip34_0897 8.6e-73 279.6 Nitrosomonadales purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 1MYN4@1224,2KKQX@206350,2VHTE@28216,COG0046@1,COG0046@2,COG0047@1,COG0047@2 NA|NA|NA F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate HFDCGJPN_01611 243231.GSU2576 8.4e-42 177.6 Deltaproteobacteria Bacteria 1RAH3@1224,2WPR9@28221,42PRF@68525,COG1639@1,COG1639@2 NA|NA|NA T PFAM Metal-dependent hydrolase HDOD HFDCGJPN_01613 583345.Mmol_0712 1.7e-93 349.0 Nitrosomonadales ompW ko:K07275 ko00000 Bacteria 1NUZJ@1224,2KKCV@206350,2VR6Y@28216,COG3047@1,COG3047@2 NA|NA|NA M PFAM OmpW family HFDCGJPN_01614 395965.Msil_1172 7.9e-32 144.4 Beijerinckiaceae Bacteria 1NDBI@1224,2U0C9@28211,3NAPD@45404,COG3174@1,COG3174@2 NA|NA|NA S Domain of unknown function (DUF4010) HFDCGJPN_01615 666681.M301_0026 0.0 1323.1 Nitrosomonadales Bacteria 1MU2C@1224,2KMH3@206350,2VH3V@28216,COG2203@1,COG2203@2,COG5001@1,COG5001@2 NA|NA|NA T GAF domain HFDCGJPN_01616 1101195.Meth11DRAFT_1249 8.5e-63 246.9 Nitrosomonadales braZ ko:K09792 ko00000 Bacteria 1PN2Q@1224,2KMZ8@206350,2VNU4@28216,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome C biogenesis protein transmembrane region HFDCGJPN_01617 1132855.KB913035_gene2099 8.6e-217 759.6 Nitrosomonadales hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1I@1224,2KM6V@206350,2VJ1F@28216,COG0635@1,COG0635@2 NA|NA|NA H Belongs to the anaerobic coproporphyrinogen-III oxidase family HFDCGJPN_01618 666681.M301_1921 3.3e-109 401.4 Nitrosomonadales anr ko:K01420 ko00000,ko03000 Bacteria 1MVGE@1224,2KM5E@206350,2VH04@28216,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein HFDCGJPN_01621 1288826.MSNKSG1_11853 9.4e-184 649.8 Alteromonadaceae mqo GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0044424,GO:0044464,GO:0055114,GO:0071944 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUCC@1224,1RRBV@1236,46A2J@72275,COG0579@1,COG0579@2 NA|NA|NA C malate quinone oxidoreductase HFDCGJPN_01622 1255043.TVNIR_1300 3e-46 191.8 Gammaproteobacteria Bacteria 1RJ22@1224,1T5AV@1236,COG3437@1,COG3437@2 NA|NA|NA KT HD domain HFDCGJPN_01623 582744.Msip34_0888 4.5e-151 540.8 Nitrosomonadales cobW Bacteria 1MVZV@1224,2KKPS@206350,2VIHH@28216,COG0523@1,COG0523@2 NA|NA|NA S PFAM cobalamin synthesis protein HFDCGJPN_01624 582744.Msip34_0892 4.8e-252 877.1 Nitrosomonadales rnb GO:0000175,GO:0000178,GO:0000932,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0022613,GO:0032991,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0035770,GO:0036464,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354,GO:1990904 3.1.13.1 ko:K01147 ko00000,ko01000,ko03016 Bacteria 1NGSQ@1224,2KMC0@206350,2VHMM@28216,COG0557@1,COG0557@2 NA|NA|NA K RNB HFDCGJPN_01625 265072.Mfla_1235 2.4e-102 378.6 Nitrosomonadales 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 1RBWW@1224,2KMEK@206350,2VK7S@28216,COG0421@1,COG0421@2 NA|NA|NA E Spermine/spermidine synthase domain HFDCGJPN_01626 582744.Msip34_0894 3.5e-179 634.4 Nitrosomonadales rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1MUQM@1224,2KMAY@206350,2VHMY@28216,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily HFDCGJPN_01627 265072.Mfla_1237 1.6e-42 178.7 Nitrosomonadales Bacteria 1N02D@1224,2KMX2@206350,2VU39@28216,COG1694@1,COG1694@2 NA|NA|NA S MazG-like family HFDCGJPN_01628 666681.M301_1640 5.3e-68 263.8 Nitrosomonadales tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1RAJ9@1224,2KKC2@206350,2VQ18@28216,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides HFDCGJPN_01629 1165096.ARWF01000001_gene47 1.9e-182 645.2 Nitrosomonadales Bacteria 1QUQH@1224,2KKQ2@206350,2VMN2@28216,COG3287@1,COG3287@2 NA|NA|NA S FIST N domain HFDCGJPN_01630 1165096.ARWF01000001_gene48 3.5e-54 217.6 Nitrosomonadales Bacteria 1RDYB@1224,2KMW5@206350,2VR2Q@28216,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver HFDCGJPN_01631 1132855.KB913035_gene1279 1.7e-39 168.7 Nitrosomonadales ko:K02658,ko:K11443 ko02020,ko02025,ko04112,map02020,map02025,map04112 M00507,M00511 ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 Bacteria 1R133@1224,2KN3M@206350,2WHYY@28216,COG0784@1,COG0784@2 NA|NA|NA T Pfam Response regulator receiver HFDCGJPN_01632 666681.M301_1636 4.8e-40 171.0 Nitrosomonadales pilI ko:K02659,ko:K03408 ko02020,ko02025,ko02030,map02020,map02025,map02030 ko00000,ko00001,ko02035,ko02044 Bacteria 1N07Q@1224,2KN3R@206350,2VU6N@28216,COG0835@1,COG0835@2 NA|NA|NA NT PFAM CheW domain protein HFDCGJPN_01633 1132855.KB913035_gene1281 1.1e-149 537.0 Nitrosomonadales pilJ ko:K02660 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko02035,ko02044 Bacteria 1MU9B@1224,2KKEZ@206350,2VJBX@28216,COG0840@1,COG0840@2 NA|NA|NA NT PFAM chemotaxis sensory transducer HFDCGJPN_01634 666681.M301_1634 0.0 1654.0 Nitrosomonadales pilL ko:K02487,ko:K06596,ko:K11526 ko02020,ko02025,map02020,map02025 M00507,M00508 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1MUAG@1224,2KKGJ@206350,2VJSZ@28216,COG0643@1,COG0643@2,COG0745@1,COG0745@2,COG2198@1,COG2198@2 NA|NA|NA T response regulator receiver HFDCGJPN_01635 582744.Msip34_1749 0.0 1942.2 Nitrosomonadales dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MUIF@1224,2KKIM@206350,2VH3F@28216,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III alpha subunit HFDCGJPN_01636 1236959.BAMT01000009_gene3402 4e-157 560.8 Nitrosomonadales accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 Bacteria 1MURN@1224,2KKTB@206350,2VHS0@28216,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA HFDCGJPN_01637 583345.Mmol_1287 5.1e-118 431.4 Nitrosomonadales tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075,ko:K14058 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1MU85@1224,2KMEJ@206350,2VP12@28216,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine HFDCGJPN_01638 1122236.KB905145_gene2422 2.5e-59 235.3 Nitrosomonadales tesA 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1RCXZ@1224,2KMTJ@206350,2VRIQ@28216,COG2755@1,COG2755@2 NA|NA|NA E PFAM lipolytic protein G-D-S-L family HFDCGJPN_01639 265072.Mfla_1251 1.2e-78 299.7 Nitrosomonadales ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MXG9@1224,2KKGV@206350,2VI54@28216,COG4181@1,COG4181@2 NA|NA|NA Q PFAM ABC transporter HFDCGJPN_01640 1122236.KB905145_gene2420 2.4e-246 858.6 Nitrosomonadales ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1MU9R@1224,2KKIP@206350,2VHHQ@28216,COG3127@1,COG3127@2 NA|NA|NA Q FtsX-like permease family HFDCGJPN_01641 582744.Msip34_1743 3.1e-240 838.2 Nitrosomonadales ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MXJU@1224,2KKMQ@206350,2VN9X@28216,COG4772@1,COG4772@2 NA|NA|NA P TonB dependent receptor HFDCGJPN_01642 666681.M301_1625 0.0 1165.6 Betaproteobacteria ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1QUWU@1224,2WGQG@28216,COG4206@1,COG4206@2 NA|NA|NA H TonB dependent receptor HFDCGJPN_01643 1236959.BAMT01000009_gene3411 2.3e-190 671.8 Nitrosomonadales atoC ko:K02481,ko:K07714 ko02020,map02020 M00500 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KKCP@206350,2VPRI@28216,COG2204@1,COG2204@2 NA|NA|NA T PFAM sigma-54 factor interaction domain-containing protein HFDCGJPN_01644 582744.Msip34_0567 5.9e-115 420.6 Nitrosomonadales bioC GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575 Bacteria 1PA5F@1224,2KM9I@206350,2VJP9@28216,COG0500@1,COG2226@2 NA|NA|NA H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway HFDCGJPN_01645 582744.Msip34_0566 5.5e-112 410.6 Nitrosomonadales bioH 2.1.1.197,3.1.1.85 ko:K02169,ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09543,R09725 RC00003,RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria 1N2R9@1224,2KKDF@206350,2VRME@28216,COG2267@1,COG2267@2 NA|NA|NA I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters HFDCGJPN_01647 582744.Msip34_0288 1.9e-32 145.2 Nitrosomonadales secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1RDI9@1224,2KN3Q@206350,2VUPV@28216,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation HFDCGJPN_01648 582744.Msip34_0289 4.4e-89 334.0 Nitrosomonadales nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1MU14@1224,2KM75@206350,2VKUA@28216,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination HFDCGJPN_01649 1236959.BAMT01000021_gene744 2.6e-71 274.6 Nitrosomonadales rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RA2M@1224,2KMP4@206350,2VPZW@28216,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors HFDCGJPN_01650 265072.Mfla_0269 5.5e-108 397.1 Nitrosomonadales rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MUE6@1224,2KKGN@206350,2VHDK@28216,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release HFDCGJPN_01651 582744.Msip34_0292 6.5e-77 293.5 Nitrosomonadales rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RAN5@1224,2KMNA@206350,2VQ7A@28216,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors HFDCGJPN_01652 1236959.BAMT01000021_gene747 7.9e-40 169.9 Nitrosomonadales rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RGU4@1224,2KMX6@206350,2VSG7@28216,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation HFDCGJPN_01653 59538.XP_005975274.1 1.5e-95 355.5 Eukaryota rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Eukaryota COG0085@1,KOG0214@2759 NA|NA|NA K DNA-directed 5'-3' RNA polymerase activity HFDCGJPN_01656 1236959.BAMT01000001_gene1754 1.4e-204 718.8 Nitrosomonadales aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1MW0Z@1224,2KKCB@206350,2VI01@28216,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II HFDCGJPN_01657 666681.M301_1438 2.9e-118 431.8 Nitrosomonadales nrfG GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0065003,GO:0071704,GO:0071840,GO:1901564 3.4.21.107 ko:K02200,ko:K04018,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1RHVK@1224,2KKD6@206350,2VT8V@28216,COG0265@1,COG0265@2,COG4235@1,COG4235@2 NA|NA|NA O Trypsin-like peptidase domain HFDCGJPN_01658 582744.Msip34_1263 0.0 1220.3 Nitrosomonadales uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1MUFK@1224,2KM2H@206350,2VHFQ@28216,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage HFDCGJPN_01659 582744.Msip34_1264 1.5e-283 982.2 Nitrosomonadales rne GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 3.1.26.12 ko:K08300 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 1MV65@1224,2KKR7@206350,2VIE5@28216,COG1530@1,COG1530@2 NA|NA|NA J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs HFDCGJPN_01661 582744.Msip34_1265 7.9e-145 520.0 Nitrosomonadales rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 ko00000,ko01000,ko03009 Bacteria 1MVDX@1224,2KMGM@206350,2VI51@28216,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil HFDCGJPN_01662 265072.Mfla_1323 5.4e-73 280.8 Nitrosomonadales gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1RDA7@1224,2KKKD@206350,2VIZ2@28216,COG0546@1,COG0546@2 NA|NA|NA S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 HFDCGJPN_01663 582744.Msip34_1267 8.3e-36 156.4 Nitrosomonadales 2.7.1.3 ko:K00846,ko:K05710 ko00051,ko00360,ko01100,ko01120,ko01220,map00051,map00360,map01100,map01120,map01220 M00545 R00866,R03819,R06782,R06783 RC00002,RC00017,RC00098,RC00608 br01602,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1N72F@1224,2KN31@206350,2VTX8@28216,COG2146@1,COG2146@2 NA|NA|NA P PFAM Rieske 2Fe-2S HFDCGJPN_01664 582744.Msip34_1268 1.6e-139 502.3 Nitrosomonadales sppA ko:K04773 ko00000,ko01000,ko01002 Bacteria 1MUXE@1224,2KKJI@206350,2VH94@28216,COG0616@1,COG0616@2 NA|NA|NA OU Peptidase family S49 HFDCGJPN_01665 582744.Msip34_1269 1.7e-272 944.9 Nitrosomonadales pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iEcSMS35_1347.EcSMS35_4486 Bacteria 1MUFP@1224,2KKUI@206350,2VHR9@28216,COG0166@1,COG0166@2 NA|NA|NA G PFAM Phosphoglucose isomerase HFDCGJPN_01666 265072.Mfla_1367 0.0 1201.8 Nitrosomonadales glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 1QTVN@1224,2KP8I@206350,2VGZZ@28216,COG0296@1,COG0296@2 NA|NA|NA F Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position HFDCGJPN_01667 582744.Msip34_1271 2.1e-222 778.1 Nitrosomonadales glgC GO:0000166,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016043,GO:0016051,GO:0016208,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0022607,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046872,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_3027,iUTI89_1310.UTI89_C3939,iYL1228.KPN_03796 Bacteria 1MVTC@1224,2KMA7@206350,2VIP2@28216,COG0448@1,COG0448@2 NA|NA|NA G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans HFDCGJPN_01668 582744.Msip34_1272 3.6e-249 867.5 Nitrosomonadales Bacteria 1P2YJ@1224,2KMC2@206350,2VHA4@28216,COG1449@1,COG1449@2 NA|NA|NA G Belongs to the glycosyl hydrolase 57 family HFDCGJPN_01669 1132855.KB913035_gene1917 1.4e-171 609.4 Nitrosomonadales malQ 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 iJN678.malQ Bacteria 1QTVJ@1224,2KKXW@206350,2VJUV@28216,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase HFDCGJPN_01670 582744.Msip34_1274 9.3e-98 363.6 Nitrosomonadales ppgK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0040007,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0047330,GO:0051156,GO:0071704,GO:1901135 2.7.1.2,2.7.1.63,5.3.1.9 ko:K00845,ko:K00886,ko:K01810 ko00010,ko00030,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114,M00549 R00299,R01600,R01786,R02187,R02189,R02739,R02740,R03321 RC00002,RC00017,RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MU94@1224,2KKT2@206350,2VMGT@28216,COG1940@1,COG1940@2 NA|NA|NA GK PFAM ROK family HFDCGJPN_01672 580332.Slit_1599 2.4e-52 216.1 Nitrosomonadales rpoC Bacteria 1MU7T@1224,2VHFJ@28216,44W46@713636,COG0739@1,COG0739@2,COG2931@1,COG2931@2 NA|NA|NA Q Hemolysin-type calcium-binding region HFDCGJPN_01673 582744.Msip34_1411 3.2e-130 471.1 Nitrosomonadales rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MU33@1224,2KKFZ@206350,2VI8V@28216,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family HFDCGJPN_01674 582744.Msip34_1412 4.4e-141 507.3 Nitrosomonadales map GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1MU99@1224,2KKEP@206350,2VH2K@28216,COG0024@1,COG0024@2 NA|NA|NA J TIGRFAM methionine aminopeptidase, type I HFDCGJPN_01675 582744.Msip34_1413 0.0 1135.6 Nitrosomonadales glnD GO:0003674,GO:0003824,GO:0006082,GO:0006355,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0045893,GO:0045935,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070569,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Bacteria 1MV54@1224,2KM41@206350,2VI2G@28216,COG2844@1,COG2844@2 NA|NA|NA O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen HFDCGJPN_01676 686340.Metal_0147 1.5e-135 490.7 Gammaproteobacteria Bacteria 1MU7T@1224,1S9I6@1236,COG2931@1,COG2931@2 NA|NA|NA Q COG2931, RTX toxins and related Ca2 -binding proteins HFDCGJPN_01677 1000565.METUNv1_00240 2.4e-43 181.0 Betaproteobacteria ko:K06995 ko00000 Bacteria 1REFN@1224,2VYDE@28216,COG3450@1,COG3450@2 NA|NA|NA S Protein of unknown function (DUF861) HFDCGJPN_01678 1163617.SCD_n01736 5.3e-228 797.0 Betaproteobacteria fumA 4.2.1.2 ko:K01676,ko:K01677,ko:K01678 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUV9@1224,2VIP7@28216,COG1838@1,COG1838@2,COG1951@1,COG1951@2 NA|NA|NA C Catalyzes the reversible hydration of fumarate to (S)- malate HFDCGJPN_01679 1112274.KI911560_gene276 3.6e-69 267.7 Nitrosomonadales ppkB 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 1MV1P@1224,2KKI3@206350,2VH5K@28216,COG0515@1,COG0515@2,COG0631@1,COG0631@2 NA|NA|NA KLT SMART protein phosphatase 2C domain protein HFDCGJPN_01680 582744.Msip34_0345 2.7e-43 181.0 Nitrosomonadales nirD 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS12545,iYO844.BSU03290 Bacteria 1N03R@1224,2KN0F@206350,2VSP4@28216,COG2146@1,COG2146@2 NA|NA|NA P TIGRFAM nitrite reductase NAD(P)H , small subunit HFDCGJPN_01684 1165096.ARWF01000001_gene2069 1.5e-302 1045.0 Nitrosomonadales ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc,iSFV_1184.SFV_4025 Bacteria 1MUD5@1224,2KM6K@206350,2VI9F@28216,COG2352@1,COG2352@2 NA|NA|NA C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle HFDCGJPN_01685 1132855.KB913035_gene1694 9.6e-131 473.8 Betaproteobacteria ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria 1P39U@1224,2VMEW@28216,COG2268@1,COG2268@2 NA|NA|NA S prohibitin homologues HFDCGJPN_01686 1165096.ARWF01000001_gene987 6.4e-88 330.5 Nitrosomonadales Bacteria 1RHYX@1224,2KKW7@206350,2VR0S@28216,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM short-chain dehydrogenase reductase SDR HFDCGJPN_01687 1095769.CAHF01000025_gene758 5.6e-180 637.5 Betaproteobacteria 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 ko00000,ko00001,ko00002,ko01000,ko02022 Bacteria 1MVWM@1224,2VK4W@28216,COG2199@1,COG3706@2 NA|NA|NA T response regulator HFDCGJPN_01688 886293.Sinac_5835 1.7e-127 463.0 Planctomycetes ko:K03305 ko00000 2.A.17 Bacteria 2IYIT@203682,COG3104@1,COG3104@2 NA|NA|NA E COG3104 Dipeptide tripeptide permease HFDCGJPN_01690 582744.Msip34_2014 1.5e-181 642.1 Nitrosomonadales ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1MVM4@1224,2KKW0@206350,2VJ1W@28216,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner HFDCGJPN_01691 583345.Mmol_1865 2.4e-46 191.4 Nitrosomonadales miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 1MURS@1224,2KKNW@206350,2VHQM@28216,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine HFDCGJPN_01692 582744.Msip34_2120 2.5e-154 551.6 Nitrosomonadales ybeZ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06217 ko00000 Bacteria 1MVDV@1224,2KM1T@206350,2VH9V@28216,COG1702@1,COG1702@2 NA|NA|NA T AAA domain HFDCGJPN_01693 582744.Msip34_2121 3.5e-60 237.7 Nitrosomonadales ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1MZ67@1224,2KMVG@206350,2VSHV@28216,COG0319@1,COG0319@2 NA|NA|NA J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA HFDCGJPN_01694 582744.Msip34_2122 7.1e-126 456.8 Nitrosomonadales corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 ko:K06189 ko00000,ko02000 9.A.40.1.2 Bacteria 1QTU8@1224,2KM7R@206350,2VIU8@28216,COG4535@1,COG4535@2 NA|NA|NA P PFAM CBS domain HFDCGJPN_01695 1101195.Meth11DRAFT_2203 3.4e-22 111.3 Nitrosomonadales Bacteria 1PJHH@1224,2BUJW@1,2KN2C@206350,2W801@28216,32PWC@2 NA|NA|NA HFDCGJPN_01696 265072.Mfla_0647 4e-53 214.2 Nitrosomonadales mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1RHG8@1224,2KN6T@206350,2VT9K@28216,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell HFDCGJPN_01697 582744.Msip34_2125 2.1e-162 578.9 Nitrosomonadales lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K03820 ko00000,ko01000 GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 Bacteria 1MUBU@1224,2KKPV@206350,2VH1I@28216,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins HFDCGJPN_01698 583345.Mmol_1761 1.1e-15 89.4 Proteobacteria Bacteria 1NBBG@1224,2A7SK@1,30WRK@2 NA|NA|NA S Protein of unknown function (DUF3240) HFDCGJPN_01699 1132855.KB913035_gene882 0.0 1589.7 Nitrosomonadales cznA ko:K07239,ko:K15726 ko00000,ko02000 2.A.6.1,2.A.6.1.2 Bacteria 1NUIV@1224,2KMG8@206350,2VHCZ@28216,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family HFDCGJPN_01700 1132855.KB913035_gene881 2.3e-132 478.8 Nitrosomonadales czcB ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 1QN99@1224,2KMK8@206350,2VQR3@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_01701 1132855.KB913035_gene880 3.5e-129 468.4 Nitrosomonadales ko:K15725 ko00000,ko02000 1.B.17.2.2 Bacteria 1RDXS@1224,2KMBD@206350,2WFIH@28216,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein HFDCGJPN_01702 1132855.KB913035_gene879 6.8e-15 87.0 Nitrosomonadales Bacteria 1PJSD@1224,2A8U8@1,2KP0K@206350,2W85M@28216,30XXG@2 NA|NA|NA HFDCGJPN_01703 1101195.Meth11DRAFT_2200 1.2e-166 592.4 Nitrosomonadales glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1MVCJ@1224,2KM9U@206350,2VIQX@28216,COG0752@1,COG0752@2 NA|NA|NA J PFAM glycyl-tRNA synthetase alpha subunit HFDCGJPN_01704 582744.Msip34_2127 6.9e-287 993.0 Nitrosomonadales glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1MV2F@1224,2KKBM@206350,2VICG@28216,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit HFDCGJPN_01705 582744.Msip34_2128 1.7e-80 305.4 Nitrosomonadales gmhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 iJN746.PP_0059 Bacteria 1RDGR@1224,2KME7@206350,2VQ49@28216,COG0241@1,COG0241@2 NA|NA|NA E TIGRFAM histidinol-phosphate phosphatase family protein HFDCGJPN_01706 265072.Mfla_0642 3.8e-96 357.8 Nitrosomonadales plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1MY51@1224,2KKR3@206350,2VNAX@28216,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases HFDCGJPN_01707 1502770.JQMG01000001_gene1370 7e-82 310.5 Nitrosomonadales ko:K07043 ko00000 Bacteria 1MXZU@1224,2KMCG@206350,2VNC5@28216,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 HFDCGJPN_01708 1333856.L686_03965 4.7e-66 257.7 Pseudomonas stutzeri group yjdF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08984 ko00000 Bacteria 1N7NB@1224,1RS4F@1236,1Z230@136846,COG3647@1,COG3647@2 NA|NA|NA S membrane HFDCGJPN_01709 582744.Msip34_2133 2.6e-19 100.9 Nitrosomonadales bfd ko:K02192 ko00000 Bacteria 1NGGY@1224,2KN7X@206350,2VWVZ@28216,COG2906@1,COG2906@2 NA|NA|NA P BFD-like [2Fe-2S] binding domain HFDCGJPN_01710 582744.Msip34_2134 2e-59 235.0 Nitrosomonadales bfr 1.16.3.1 ko:K03594 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 1RCW7@1224,2KMPX@206350,2VPZP@28216,COG2193@1,COG2193@2 NA|NA|NA P Ferritin-like domain HFDCGJPN_01711 582744.Msip34_0082 8.8e-162 576.6 Nitrosomonadales pilC2 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MV4U@1224,2KKSQ@206350,2VI1J@28216,COG1459@1,COG1459@2 NA|NA|NA NU PFAM type II secretion system HFDCGJPN_01712 1165096.ARWF01000001_gene1419 2.3e-277 961.1 Nitrosomonadales xcpR 4.6.1.1 ko:K01768,ko:K02454,ko:K02652 ko00230,ko02025,ko03070,ko04113,ko04213,ko05111,map00230,map02025,map03070,map04113,map04213,map05111 M00331,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MU7V@1224,2KKZR@206350,2VHQ1@28216,COG2804@1,COG2804@2 NA|NA|NA NU General secretory system II protein E domain protein HFDCGJPN_01713 582744.Msip34_0080 7.8e-66 258.1 Bacteria trxA ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 iIT341.HP0824 Bacteria COG3118@1,COG3118@2 NA|NA|NA O belongs to the thioredoxin family HFDCGJPN_01714 1101195.Meth11DRAFT_0140 1.1e-201 709.9 Nitrosomonadales outD ko:K02453,ko:K12282 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1MVNC@1224,2KKGD@206350,2VMT1@28216,COG1450@1,COG1450@2 NA|NA|NA NU type II and III secretion system protein HFDCGJPN_01715 1165096.ARWF01000001_gene1422 2.2e-150 539.3 Nitrosomonadales exeA1 ko:K12283 ko00000,ko02044 Bacteria 1MU3G@1224,2KKBN@206350,2VMD2@28216,COG3267@1,COG3267@2 NA|NA|NA U PFAM Sporulation domain protein HFDCGJPN_01716 265072.Mfla_0074 1.2e-210 739.2 Nitrosomonadales ko:K07712 ko02020,map02020 M00497 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KMCT@206350,2VNYV@28216,COG2204@1,COG2204@2 NA|NA|NA T PFAM sigma-54 factor interaction domain-containing protein HFDCGJPN_01720 582744.Msip34_0076 1e-124 453.0 Nitrosomonadales folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWU4@1224,2KM3C@206350,2VI8C@28216,COG0190@1,COG0190@2 NA|NA|NA H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate HFDCGJPN_01721 582744.Msip34_0075 1.2e-70 272.3 Nitrosomonadales dksA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 1RD08@1224,2KMKT@206350,2VRPJ@28216,COG1734@1,COG1734@2 NA|NA|NA T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters HFDCGJPN_01722 582744.Msip34_0074 0.0 1241.1 Nitrosomonadales pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1MVB9@1224,2KMDT@206350,2VI1P@28216,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction HFDCGJPN_01723 1132855.KB913035_gene2631 4.1e-35 153.7 Nitrosomonadales rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ2W@1224,2KN40@206350,2VU1D@28216,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome HFDCGJPN_01724 1165096.ARWF01000001_gene1428 2.2e-120 438.7 Nitrosomonadales truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 1MV0N@1224,2KKM9@206350,2VH97@28216,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs HFDCGJPN_01725 582744.Msip34_0071 8.2e-47 193.0 Nitrosomonadales rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1MZPE@1224,2KMXN@206350,2VR43@28216,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA HFDCGJPN_01726 583345.Mmol_2321 2.7e-262 911.0 Nitrosomonadales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF987.Gmet_1434 Bacteria 1MU4J@1224,2KM4P@206350,2VHT1@28216,COG0018@1,COG0018@2 NA|NA|NA J TIGRFAM arginyl-tRNA synthetase HFDCGJPN_01727 582744.Msip34_2808 4.6e-50 204.5 Nitrosomonadales ftsN ko:K03642 ko00000 Bacteria 1RIU5@1224,2KMUG@206350,2VTKT@28216,COG3087@1,COG3087@2 NA|NA|NA D PFAM Sporulation domain protein HFDCGJPN_01728 582744.Msip34_2809 3.8e-79 301.2 Nitrosomonadales dsbA ko:K03673 ko01503,map01503 M00728 ko00000,ko00001,ko00002,ko03110 Bacteria 1RGWH@1224,2KKWZ@206350,2VSFV@28216,COG1651@1,COG1651@2 NA|NA|NA O Thiol disulfide interchange protein HFDCGJPN_01729 1165096.ARWF01000001_gene1620 8.4e-92 343.6 Nitrosomonadales wcbP Bacteria 1PNDU@1224,2KMGJ@206350,2VIWD@28216,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family HFDCGJPN_01730 583345.Mmol_2325 9e-298 1028.9 Nitrosomonadales yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 ko00000,ko01000 Bacteria 1MU37@1224,2KNFK@206350,2VHES@28216,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter HFDCGJPN_01731 1101195.Meth11DRAFT_2633 3.8e-189 667.9 Nitrosomonadales mdoB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006490,GO:0006629,GO:0008150,GO:0008152,GO:0008960,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0042597,GO:0044237,GO:0044238,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576 2.7.8.20 ko:K01002 ko01100,map01100 ko00000,ko01000 Bacteria 1PJPD@1224,2KNNC@206350,2W83A@28216,COG1368@1,COG1368@2 NA|NA|NA M Sulfatase HFDCGJPN_01732 697282.Mettu_0469 1.1e-106 393.7 Methylococcales Bacteria 1MZV7@1224,1SA8X@1236,1XFJF@135618,COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase HFDCGJPN_01733 582744.Msip34_2812 1.9e-296 1024.6 Nitrosomonadales glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 Bacteria 1MW4K@1224,2KKU5@206350,2VHVY@28216,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source HFDCGJPN_01734 1165096.ARWF01000001_gene1585 1.2e-170 606.3 Nitrosomonadales glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Bacteria 1MUPH@1224,2KMGD@206350,2VH54@28216,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain HFDCGJPN_01735 582744.Msip34_2814 1.9e-50 205.3 Nitrosomonadales atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01195 Bacteria 1RHE4@1224,2KMM0@206350,2VR2R@28216,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane HFDCGJPN_01736 59538.XP_005975242.1 4.1e-251 873.6 Cetartiodactyla Mammalia 38CQ6@33154,3BAHK@33208,3CV2G@33213,3J5C0@40674,4851Z@7711,497E8@7742,4IZEE@91561,COG0055@1,KOG1350@2759 NA|NA|NA C ATP synthase subunit beta HFDCGJPN_01737 1122236.KB905145_gene2485 1e-132 479.6 Nitrosomonadales atpG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611 Bacteria 1MU28@1224,2KKJZ@206350,2VJBW@28216,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex HFDCGJPN_01738 1236959.BAMT01000007_gene2618 1.2e-84 319.3 Nitrosomonadales atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1MUG7@1224,2KKGG@206350,2VHQU@28216,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit HFDCGJPN_01739 582744.Msip34_1878 1.3e-208 732.3 Nitrosomonadales carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUDZ@1224,2KKQ5@206350,2VI4A@28216,COG0458@1,COG0458@2 NA|NA|NA EF PFAM Carbamoyl-phosphate synthase L chain HFDCGJPN_01740 582744.Msip34_1877 1.7e-68 265.4 Nitrosomonadales greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 1RCXW@1224,2KMNE@206350,2VQ16@28216,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides HFDCGJPN_01741 582744.Msip34_1876 6.9e-51 206.8 Nitrosomonadales Bacteria 1RJPF@1224,2AJXH@1,2KMQM@206350,2VTF5@28216,31AKJ@2 NA|NA|NA S Domain of unknown function (DUF4149) HFDCGJPN_01742 1236959.BAMT01000001_gene1041 4e-36 157.1 Nitrosomonadales yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1N8K5@1224,2KMZK@206350,2VVP0@28216,COG1534@1,COG1534@2 NA|NA|NA J CRS1_YhbY HFDCGJPN_01743 582744.Msip34_1874 1.8e-97 362.1 Nitrosomonadales ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 ko00000,ko01000,ko03009 Bacteria 1MW1C@1224,2KKEA@206350,2VIU9@28216,COG0293@1,COG0293@2 NA|NA|NA J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit HFDCGJPN_01744 582744.Msip34_1873 0.0 1126.7 Nitrosomonadales ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1MU6J@1224,2KM49@206350,2VHEV@28216,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins HFDCGJPN_01745 582744.Msip34_1872 4.7e-100 370.9 Nitrosomonadales folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_3924,iPC815.YPO3501 Bacteria 1MUIR@1224,2KKPU@206350,2VH2Q@28216,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives HFDCGJPN_01746 582744.Msip34_1871 2.5e-197 694.9 Nitrosomonadales glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1MU24@1224,2KKGB@206350,2VI3U@28216,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate HFDCGJPN_01747 1502770.JQMG01000001_gene65 8.7e-92 344.0 Nitrosomonadales Bacteria 1R35E@1224,28IX1@1,2KKKU@206350,2VQUH@28216,2ZC5T@2 NA|NA|NA S Protein of unknown function (DUF2914) HFDCGJPN_01748 582744.Msip34_2617 6.5e-107 393.3 Nitrosomonadales thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c45100 Bacteria 1MUVV@1224,2KKSI@206350,2VHS3@28216,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction HFDCGJPN_01749 265072.Mfla_2529 1.6e-136 492.7 Nitrosomonadales rluF 3.6.4.13,5.4.99.21 ko:K03578,ko:K06182 ko00000,ko01000,ko03009 Bacteria 1MXQE@1224,2KMFQ@206350,2VI7P@28216,COG1187@1,COG1187@2,COG3170@1,COG3170@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family HFDCGJPN_01750 666681.M301_2745 1.2e-87 329.7 Nitrosomonadales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1MX02@1224,2KM3M@206350,2VHSA@28216,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin HFDCGJPN_01751 582744.Msip34_2613 7.3e-75 287.0 Nitrosomonadales exoD Bacteria 1REE4@1224,2KNKU@206350,2VXYC@28216,COG3932@1,COG3932@2 NA|NA|NA S Exopolysaccharide synthesis, ExoD HFDCGJPN_01752 582744.Msip34_2612 6.1e-309 1066.6 Nitrosomonadales asmA ko:K07289,ko:K07290 ko00000 9.B.121 Bacteria 1NVUY@1224,2KMI1@206350,2VI5J@28216,COG2982@1,COG2982@2 NA|NA|NA M PFAM AsmA family HFDCGJPN_01753 1123400.KB904753_gene1067 6.3e-38 163.7 Proteobacteria ko:K08978,ko:K12962 ko01503,map01503 M00721 ko00000,ko00001,ko00002,ko01005,ko02000 2.A.7.2,2.A.7.22 Bacteria 1RIRZ@1224,COG2510@1,COG2510@2 NA|NA|NA S EamA-like transporter family HFDCGJPN_01754 666681.M301_2748 3.7e-145 521.2 Nitrosomonadales mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MUD4@1224,2KKYG@206350,2VH21@28216,COG1194@1,COG1194@2 NA|NA|NA L TIGRFAM A G-specific adenine glycosylase HFDCGJPN_01755 1173028.ANKO01000216_gene6188 8.1e-25 123.6 Oscillatoriales 3.2.1.8 ko:K01181,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 1G0ZC@1117,1H8KD@1150,COG0689@1,COG0689@2,COG2931@1,COG2931@2,COG5184@1,COG5184@2 NA|NA|NA Q PFAM Hemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_01756 1117319.PSPO_01101 2e-12 78.2 Pseudoalteromonadaceae Bacteria 1N75V@1224,1TB5V@1236,2EH60@1,2Q3AH@267888,33AXW@2 NA|NA|NA S Protein of unknown function (DUF2798) HFDCGJPN_01757 1165096.ARWF01000001_gene917 2.5e-77 295.4 Nitrosomonadales fliR ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1NIF4@1224,2KM5Q@206350,2VQ64@28216,COG1684@1,COG1684@2 NA|NA|NA N Role in flagellar biosynthesis HFDCGJPN_01758 582744.Msip34_0767 3.4e-29 134.0 Nitrosomonadales fliQ ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1N73W@1224,2KN3B@206350,2VU8S@28216,COG1987@1,COG1987@2 NA|NA|NA N Role in flagellar biosynthesis HFDCGJPN_01759 666681.M301_1012 1.2e-95 356.3 Nitrosomonadales fliP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02419,ko:K03226 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 Bacteria 1MVBU@1224,2KKP6@206350,2VIU6@28216,COG1338@1,COG1338@2 NA|NA|NA N Plays a role in the flagellum-specific transport system HFDCGJPN_01760 582744.Msip34_0765 6.3e-20 104.0 Nitrosomonadales fliO ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 1PQ30@1224,2KN9H@206350,2VWHP@28216,COG3190@1,COG3190@2 NA|NA|NA N PFAM Flagellar biosynthesis protein, FliO HFDCGJPN_01761 1236959.BAMT01000016_gene2767 2.1e-54 218.4 Nitrosomonadales fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 Bacteria 1RGWT@1224,2KMVJ@206350,2VSZ7@28216,COG1886@1,COG1886@2 NA|NA|NA N PFAM surface presentation of antigens (SPOA) HFDCGJPN_01762 1236959.BAMT01000016_gene2768 1.3e-161 575.9 Nitrosomonadales fliM GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 Bacteria 1MX01@1224,2KKQT@206350,2VI0A@28216,COG1868@1,COG1868@2 NA|NA|NA N TIGRFAM flagellar motor switch protein FliM HFDCGJPN_01763 582744.Msip34_0762 4.3e-28 131.3 Nitrosomonadales fliL GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009425,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 ko:K02415 ko00000,ko02035 Bacteria 1RARK@1224,2KP74@206350,2VTXC@28216,COG1580@1,COG1580@2 NA|NA|NA N Flagellar basal body-associated protein FliL HFDCGJPN_01765 582744.Msip34_0539 2.5e-244 851.7 Nitrosomonadales oprC ko:K02014 ko00000,ko02000 1.B.14 Bacteria 1MW7D@1224,2KNKX@206350,2VIV2@28216,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug Domain HFDCGJPN_01766 582744.Msip34_0515 4.3e-171 607.4 Nitrosomonadales proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_3198 Bacteria 1MUBG@1224,2KKSK@206350,2VISR@28216,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate HFDCGJPN_01767 582744.Msip34_0514 4.4e-170 604.0 Nitrosomonadales obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1MUGZ@1224,2KKUT@206350,2VIM2@28216,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control HFDCGJPN_01768 582744.Msip34_0513 7.1e-37 159.5 Nitrosomonadales rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZGH@1224,2KN2Y@206350,2VU4W@28216,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family HFDCGJPN_01769 582744.Msip34_0512 9.6e-44 182.6 Nitrosomonadales rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZEW@1224,2KMZW@206350,2VSHZ@28216,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 HFDCGJPN_01770 582744.Msip34_0511 1.1e-138 499.6 Nitrosomonadales ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 iYL1228.KPN_03597,ic_1306.c3945 Bacteria 1MUK6@1224,2KKIW@206350,2VHX4@28216,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family HFDCGJPN_01771 1095769.CAHF01000013_gene3393 1.3e-144 520.4 Oxalobacteraceae Bacteria 1MVMG@1224,2VH3M@28216,475M3@75682,COG0457@1,COG0457@2,COG3914@1,COG3914@2 NA|NA|NA O Glycosyl transferase family 41 HFDCGJPN_01772 265072.Mfla_2224 6.8e-37 159.8 Nitrosomonadales Bacteria 1PJHU@1224,2A8KA@1,2KN46@206350,2W804@28216,30XNN@2 NA|NA|NA HFDCGJPN_01773 666681.M301_0527 5.7e-110 404.1 Nitrosomonadales pilD 3.4.23.43 ko:K02654 M00331 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1MUZF@1224,2KKDG@206350,2VI08@28216,COG1989@1,COG1989@2 NA|NA|NA NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue HFDCGJPN_01774 265072.Mfla_2226 1.4e-75 289.3 Nitrosomonadales coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_0104 Bacteria 1RCXT@1224,2KMWF@206350,2VR8K@28216,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A HFDCGJPN_01775 582744.Msip34_0507 4.6e-108 397.5 Nitrosomonadales zapD GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301 ko:K18778 ko00000,ko03036 Bacteria 1MW69@1224,2KKRA@206350,2VIIG@28216,COG4582@1,COG4582@2 NA|NA|NA D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity HFDCGJPN_01776 265072.Mfla_2228 1.1e-15 88.6 Nitrosomonadales yacG GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 ko:K00859,ko:K09862 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1NGJ8@1224,2KN8A@206350,2VXRV@28216,COG3024@1,COG3024@2 NA|NA|NA S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase HFDCGJPN_01777 1165096.ARWF01000001_gene2121 5.8e-34 150.6 Nitrosomonadales ko:K09796 ko00000,ko03110 Bacteria 1N3BG@1224,2KN4H@206350,2VX2P@28216,COG2847@1,COG2847@2 NA|NA|NA S Copper chaperone PCu(A)C HFDCGJPN_01778 1236959.BAMT01000002_gene2177 6.6e-19 100.5 Nitrosomonadales Bacteria 1N26T@1224,2BWYA@1,2KNZC@206350,2VXGX@28216,32WXT@2 NA|NA|NA HFDCGJPN_01779 582744.Msip34_0504 1.8e-109 402.5 Nitrosomonadales mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.5.1.3,3.6.1.55,3.6.1.65 ko:K00788,ko:K03574,ko:K08320 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000,ko03400 iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 Bacteria 1RCZM@1224,2KM02@206350,2VHTP@28216,COG0352@1,COG0352@2,COG0494@1,COG0494@2 NA|NA|NA HL Thiamine monophosphate synthase HFDCGJPN_01780 265072.Mfla_2231 3.1e-119 434.9 Nitrosomonadales MA20_41470 ko:K06923 ko00000 Bacteria 1MVMX@1224,2KKTH@206350,2VID5@28216,COG2607@1,COG2607@2 NA|NA|NA S Protein of unknown function (DUF815) HFDCGJPN_01781 582744.Msip34_0502 1.4e-183 649.0 Nitrosomonadales argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1783 Bacteria 1MU0T@1224,2KMBY@206350,2VJ84@28216,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate HFDCGJPN_01782 580332.Slit_0536 0.0 1092.8 Nitrosomonadales gspE2 ko:K02652 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1MU7V@1224,2VHQ1@28216,44VNC@713636,COG2804@1,COG2804@2 NA|NA|NA NU General secretory system II protein E domain protein HFDCGJPN_01783 582744.Msip34_2262 0.0 2325.1 Nitrosomonadales glpCD 1.1.2.4,1.97.1.9 ko:K00102,ko:K12527 ko00450,ko00620,map00450,map00620 R00197,R07229 RC00044,RC02420 ko00000,ko00001,ko01000 Bacteria 1MU43@1224,2KKK3@206350,2VHYU@28216,COG0247@1,COG0247@2,COG0277@1,COG0277@2,COG0479@1,COG0479@2 NA|NA|NA C PFAM FAD linked oxidase domain protein HFDCGJPN_01784 1165096.ARWF01000001_gene1114 8.9e-55 219.9 Nitrosomonadales resA Bacteria 1RDGI@1224,2KMUP@206350,2VT2S@28216,COG0526@1,COG0526@2 NA|NA|NA CO SCO1/SenC HFDCGJPN_01785 1266925.JHVX01000003_gene430 1.1e-63 249.2 Nitrosomonadales ko:K08973 ko00000 Bacteria 1RHGS@1224,2VR5Y@28216,3737C@32003,COG1981@1,COG1981@2 NA|NA|NA S Uncharacterised protein family (UPF0093) HFDCGJPN_01786 1101195.Meth11DRAFT_0557 2.9e-54 218.8 Nitrosomonadales Bacteria 1PJHD@1224,2A8JX@1,2KN1Q@206350,2W7ZW@28216,30XN8@2 NA|NA|NA HFDCGJPN_01787 582744.Msip34_2267 2.2e-78 298.5 Nitrosomonadales Bacteria 1R67Z@1224,2KMDX@206350,2VUQ0@28216,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family HFDCGJPN_01788 1101195.Meth11DRAFT_0555 4.9e-144 517.3 Nitrosomonadales adoK GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2683 Bacteria 1PDQE@1224,2KM32@206350,2VHMF@28216,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase HFDCGJPN_01789 582744.Msip34_2269 4e-46 191.0 Nitrosomonadales slyB ko:K06077 ko00000 Bacteria 1RJWY@1224,2KMTH@206350,2WE8P@28216,COG3133@1,COG3133@2 NA|NA|NA M PFAM 17 kDa surface antigen HFDCGJPN_01790 582744.Msip34_2270 4.5e-116 424.1 Nitrosomonadales Bacteria 1MWIM@1224,2KKWY@206350,2VH4B@28216,COG3176@1,COG3176@2 NA|NA|NA S Acetyltransferase (GNAT) domain HFDCGJPN_01791 582744.Msip34_2271 5.6e-85 320.9 Nitrosomonadales plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1N2DG@1224,2KMKH@206350,2VSJD@28216,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases HFDCGJPN_01792 582744.Msip34_2272 5.1e-108 397.5 Nitrosomonadales apaH GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 ko:K01525 ko00230,map00230 R00125 RC00002 ko00000,ko00001,ko01000 iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074 Bacteria 1MV10@1224,2KKMZ@206350,2VHV6@28216,COG0639@1,COG0639@2 NA|NA|NA T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP HFDCGJPN_01793 582744.Msip34_2273 4.8e-61 240.7 Nitrosomonadales Bacteria 1MZBZ@1224,2KN03@206350,2VMBB@28216,COG3245@1,COG3245@2 NA|NA|NA C PFAM Cytochrome C HFDCGJPN_01795 1101195.Meth11DRAFT_0501 3.3e-121 441.4 Nitrosomonadales ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 iJN746.PP_0110 Bacteria 1MW3S@1224,2KM3K@206350,2VHZU@28216,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group HFDCGJPN_01796 666681.M301_2282 2.7e-119 435.3 Nitrosomonadales ctaA ko:K02259,ko:K03110 ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714 M00154,M00335 R07412 RC00769 ko00000,ko00001,ko00002,ko02044,ko03029 3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4 Bacteria 1MVJ4@1224,2KMJI@206350,2VJ3C@28216,COG1612@1,COG1612@2 NA|NA|NA O PFAM Cytochrome oxidase assembly HFDCGJPN_01797 1165096.ARWF01000001_gene1126 1.5e-48 199.5 Nitrosomonadales VVA1110 Bacteria 1N6R6@1224,2KMZH@206350,2VXI0@28216,COG1999@1,COG1999@2 NA|NA|NA S signal sequence binding HFDCGJPN_01798 582744.Msip34_1210 7.7e-63 247.3 Nitrosomonadales surf1 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 1MZUH@1224,2KN59@206350,2VSAZ@28216,COG3346@1,COG3346@2 NA|NA|NA S SURF1 family HFDCGJPN_01799 666681.M301_2285 6.3e-12 76.3 Nitrosomonadales VL23_10685 Bacteria 1NH9B@1224,2EGIJ@1,2KNAK@206350,2W81A@28216,33AAQ@2 NA|NA|NA S Protein of unknown function (DUF2909) HFDCGJPN_01800 1132855.KB913035_gene2289 5.3e-132 477.2 Nitrosomonadales ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 iJN678.ctaE Bacteria 1MUCK@1224,2KMDS@206350,2VJAP@28216,COG1845@1,COG1845@2 NA|NA|NA C PFAM cytochrome c oxidase subunit III HFDCGJPN_01801 1132855.KB913035_gene2288 2.7e-62 245.0 Nitrosomonadales ctaG GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 ko00000,ko00001,ko00002,ko03029 3.D.4.8 Bacteria 1RDTU@1224,2KMKF@206350,2VHRQ@28216,COG3175@1,COG3175@2 NA|NA|NA O PFAM Cytochrome c oxidase assembly protein CtaG Cox11 HFDCGJPN_01802 1101195.Meth11DRAFT_0494 4.4e-294 1016.5 Nitrosomonadales 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 1MU7S@1224,2KKYM@206350,2VHGU@28216,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B HFDCGJPN_01803 582744.Msip34_1216 2.9e-178 631.3 Nitrosomonadales ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1MWHZ@1224,2KM4R@206350,2VH9M@28216,COG1622@1,COG1622@2,COG2010@1,COG2010@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) HFDCGJPN_01804 582744.Msip34_1217 2e-33 148.7 Nitrosomonadales Bacteria 1N5Z9@1224,2KN5A@206350,2VU1W@28216,COG5488@1,COG5488@2 NA|NA|NA S Integral membrane protein (DUF2244) HFDCGJPN_01806 265072.Mfla_0423 5.4e-136 490.7 Nitrosomonadales queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 ko:K00773,ko:K07568 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1MUH3@1224,2KKJW@206350,2VHJF@28216,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) HFDCGJPN_01807 1112274.KI911560_gene564 5.4e-108 397.5 Nitrosomonadales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1NRNR@1224,2KM2F@206350,2W165@28216,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity HFDCGJPN_01808 1165096.ARWF01000001_gene1135 4.1e-47 194.5 Nitrosomonadales Bacteria 1N035@1224,2DNBK@1,2KNGR@206350,2VVXR@28216,32WMY@2 NA|NA|NA S Protein of unknown function (DUF1097) HFDCGJPN_01809 582744.Msip34_2278 4.9e-81 307.4 Nitrosomonadales ko:K08307 ko00000,ko01000,ko01011 Bacteria 1R666@1224,2KKV2@206350,2VHI4@28216,COG0741@1,COG0741@2 NA|NA|NA M Transglycosylase SLT domain HFDCGJPN_01810 1236959.BAMT01000005_gene97 7.2e-274 949.5 Nitrosomonadales proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1MU7E@1224,2KKEY@206350,2VGZ9@28216,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS HFDCGJPN_01811 582744.Msip34_2280 1e-56 226.5 Nitrosomonadales Bacteria 1N74F@1224,2CDCV@1,2KMRH@206350,2VSMP@28216,308Y1@2 NA|NA|NA HFDCGJPN_01812 264198.Reut_C6200 6.4e-42 177.2 Burkholderiaceae Z012_08985 ko:K08988 ko00000 Bacteria 1K75J@119060,1R61N@1224,2VRJE@28216,COG3762@1,COG3762@2 NA|NA|NA S TPM domain HFDCGJPN_01813 1236959.BAMT01000005_gene93 7.4e-75 287.3 Nitrosomonadales ko:K06872 ko00000 Bacteria 1PB41@1224,2KKKF@206350,2VMNV@28216,COG1512@1,COG1512@2 NA|NA|NA S TPM domain HFDCGJPN_01814 582744.Msip34_2283 1.6e-84 318.9 Nitrosomonadales lemA ko:K03744 ko00000 Bacteria 1MVH0@1224,2KKPP@206350,2VHT5@28216,COG1704@1,COG1704@2 NA|NA|NA S PFAM LemA family HFDCGJPN_01815 582744.Msip34_2284 1.3e-98 366.3 Betaproteobacteria dpo 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MWX1@1224,2VPZQ@28216,COG1573@1,COG1573@2 NA|NA|NA L uracil-DNA glycosylase HFDCGJPN_01816 265072.Mfla_0413 3.4e-55 221.1 Nitrosomonadales rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 1RIE6@1224,2KMVP@206350,2VUIW@28216,COG0454@1,COG0456@2 NA|NA|NA K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 HFDCGJPN_01817 582744.Msip34_2286 7.1e-72 277.3 Nitrosomonadales yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1MXPH@1224,2KMK0@206350,2VQR7@28216,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family HFDCGJPN_01818 1122604.JONR01000061_gene2112 8.6e-82 310.5 Xanthomonadales wbxY Bacteria 1MY5B@1224,1RRVD@1236,1X6GP@135614,2C1VH@1,2Z7Z3@2 NA|NA|NA S 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase HFDCGJPN_01820 1235457.C404_24280 1.5e-28 131.7 Burkholderiaceae ypeB 2.7.7.7 ko:K02342,ko:K09954,ko:K10857 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1K9BT@119060,1N7GT@1224,2VW2G@28216,COG3530@1,COG3530@2 NA|NA|NA S Putative quorum-sensing-regulated virulence factor HFDCGJPN_01821 748247.AZKH_4524 1.6e-19 104.8 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KZTM@206389,2VNQ5@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_01823 582744.Msip34_2300 9.3e-235 819.3 Nitrosomonadales dinG GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 1MVCU@1224,2KKUU@206350,2VH0V@28216,COG1199@1,COG1199@2 NA|NA|NA L HELICc2 HFDCGJPN_01824 1387312.BAUS01000011_gene1877 4.6e-171 607.4 Betaproteobacteria gluP ko:K02429 ko00000,ko02000 2.A.1.7 Bacteria 1MXDC@1224,2VN8R@28216,COG0738@1,COG0738@2 NA|NA|NA G glucose galactose transporter HFDCGJPN_01825 1101195.Meth11DRAFT_0937 3.9e-104 384.4 Nitrosomonadales hom GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1MUDC@1224,2KMC7@206350,2VH9T@28216,COG0460@1,COG0460@2 NA|NA|NA E amino acid-binding ACT domain protein HFDCGJPN_01826 1502770.JQMG01000001_gene2356 1e-233 815.8 Nitrosomonadales thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUWQ@1224,2KMEQ@206350,2VHR6@28216,COG0498@1,COG0498@2 NA|NA|NA E TIGRFAM threonine synthase HFDCGJPN_01827 1236959.BAMT01000001_gene1208 2.8e-140 504.6 Nitrosomonadales thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUBD@1224,2KM56@206350,2VIIR@28216,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis HFDCGJPN_01828 1236959.BAMT01000003_gene491 4.1e-73 283.1 Nitrosomonadales Bacteria 1MU7T@1224,2KP8N@206350,2WF3H@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_01829 583345.Mmol_1276 2.4e-71 275.0 Nitrosomonadales ykoJ Bacteria 1N2PN@1224,2KMS2@206350,2VVWQ@28216,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain HFDCGJPN_01830 640081.Dsui_2362 5.8e-28 131.0 Betaproteobacteria pcp ko:K06077 ko00000 Bacteria 1N18D@1224,2VU4M@28216,COG3133@1,COG3133@2 NA|NA|NA M PFAM 17 kDa surface antigen HFDCGJPN_01832 582744.Msip34_0881 7.8e-30 137.1 Bacteria osmY GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 ko:K04065 ko00000 Bacteria COG2823@1,COG2823@2 NA|NA|NA S hyperosmotic response HFDCGJPN_01833 582744.Msip34_0882 9.6e-205 719.5 Nitrosomonadales yfhA ko:K07715 ko02020,ko02024,map02020,map02024 M00502 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KM7W@206350,2VHSB@28216,COG2204@1,COG2204@2 NA|NA|NA T Sigma-54 interaction domain HFDCGJPN_01834 582744.Msip34_0883 2.5e-26 125.6 Nitrosomonadales Bacteria 1PJJ3@1224,2BUKV@1,2KN8I@206350,2W80V@28216,32PXE@2 NA|NA|NA HFDCGJPN_01835 582744.Msip34_0884 2.7e-162 578.6 Nitrosomonadales Bacteria 1N58A@1224,2KKG4@206350,2VHVP@28216,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phospho-acceptor) domain HFDCGJPN_01836 666681.M301_1108 3.4e-64 251.1 Nitrosomonadales folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1RH0P@1224,2KMR3@206350,2VSH8@28216,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis HFDCGJPN_01837 582744.Msip34_0887 0.0 1449.5 Nitrosomonadales adiA 4.1.1.19 ko:K01584,ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1MWK4@1224,2KKF1@206350,2VIJQ@28216,COG1982@1,COG1982@2 NA|NA|NA E PFAM Orn Lys Arg decarboxylase major region HFDCGJPN_01838 1132855.KB913035_gene1099 5.6e-100 370.2 Nitrosomonadales dcd GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV2J@1224,2KMDH@206350,2VIJ0@28216,COG0717@1,COG0717@2 NA|NA|NA F Belongs to the dCTP deaminase family HFDCGJPN_01839 582744.Msip34_1093 4.1e-195 687.2 Nitrosomonadales zwf 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1MUN0@1224,2KM88@206350,2VHS1@28216,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone HFDCGJPN_01840 1132855.KB913035_gene794 7.4e-37 159.8 Nitrosomonadales Bacteria 1MZ60@1224,2KNW1@206350,2VWQ0@28216,COG3952@1,COG3952@2 NA|NA|NA S Lipid A Biosynthesis N-terminal domain HFDCGJPN_01841 1132855.KB913035_gene795 5.8e-92 344.0 Nitrosomonadales arnC 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 1MWE5@1224,2KNJ2@206350,2VJ5G@28216,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 HFDCGJPN_01842 1502770.JQMG01000001_gene1482 3e-76 291.6 Nitrosomonadales 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1R9XQ@1224,2KMUQ@206350,2W4RY@28216,COG0546@1,COG0546@2 NA|NA|NA S PFAM Haloacid dehalogenase domain protein hydrolase HFDCGJPN_01843 1132855.KB913035_gene922 6.5e-100 370.2 Nitrosomonadales eda GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 iECOK1_1307.ECOK1_1968,iYL1228.KPN_02365 Bacteria 1MUVJ@1224,2KM9F@206350,2VQWM@28216,COG0800@1,COG0800@2 NA|NA|NA G PFAM KDPG and KHG aldolase HFDCGJPN_01844 582744.Msip34_1897 6.1e-292 1009.6 Nitrosomonadales edd GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366 Bacteria 1MU3T@1224,2KMF8@206350,2VHH2@28216,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family HFDCGJPN_01845 1132855.KB913035_gene920 1.5e-295 1021.5 Nitrosomonadales HA62_32075 ko:K00612 ko00000,ko01000 Bacteria 1MWBA@1224,2KKWD@206350,2VHAK@28216,COG2192@1,COG2192@2 NA|NA|NA O Carbamoyltransferase C-terminus HFDCGJPN_01846 1101195.Meth11DRAFT_1930 1.7e-103 383.3 Nitrosomonadales Bacteria 1QY37@1224,2KKE5@206350,2VKUD@28216,COG1718@1,COG1718@2 NA|NA|NA DT Lipopolysaccharide kinase (Kdo/WaaP) family HFDCGJPN_01847 522306.CAP2UW1_1842 7.3e-46 190.7 Betaproteobacteria 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 1Q73B@1224,2W6KU@28216,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase domain HFDCGJPN_01848 582744.Msip34_1901 8.5e-57 227.3 Nitrosomonadales Bacteria 1RI1E@1224,2KP9V@206350,2WGF8@28216,COG0515@1,COG0515@2 NA|NA|NA KLT Lipopolysaccharide kinase (Kdo/WaaP) family HFDCGJPN_01849 1123354.AUDR01000013_gene533 2.2e-98 366.3 Hydrogenophilales arnT_1 Bacteria 1KTF4@119069,1NMIZ@1224,2VMHK@28216,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase HFDCGJPN_01850 582744.Msip34_1902 4.5e-85 321.2 Nitrosomonadales Bacteria 1MXX9@1224,2KM93@206350,2VHSR@28216,COG0515@1,COG0515@2 NA|NA|NA KLT Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core HFDCGJPN_01851 1165096.ARWF01000001_gene859 8.5e-103 380.6 Nitrosomonadales rfaG GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K02844 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT4 iSDY_1059.SDY_4061 Bacteria 1NE3V@1224,2KMF4@206350,2VJET@28216,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 HFDCGJPN_01852 1165096.ARWF01000001_gene860 6.4e-78 297.7 Nitrosomonadales rfaC ko:K02841 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT9 Bacteria 1MYZA@1224,2KM9K@206350,2VPK7@28216,COG0859@1,COG0859@2 NA|NA|NA M TIGRFAM lipopolysaccharide heptosyltransferase I HFDCGJPN_01853 582744.Msip34_1905 8e-64 250.0 Nitrosomonadales grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1RH8T@1224,2KMM6@206350,2VSEQ@28216,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ HFDCGJPN_01854 748247.AZKH_4524 3.6e-21 110.9 Rhodocyclales avxIA Bacteria 1MU7T@1224,2KZTM@206389,2VNQ5@28216,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) HFDCGJPN_01855 484770.UFO1_0077 5.4e-43 183.7 Negativicutes avxIA 3.4.24.40 ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 Bacteria 1U2V0@1239,4H5TB@909932,COG2931@1,COG2931@2 NA|NA|NA OQ Haemolysin-type calcium binding protein related domain HFDCGJPN_01856 582744.Msip34_1906 0.0 1138.6 Nitrosomonadales dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1MVEN@1224,2KKXR@206350,2VH14@28216,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein HFDCGJPN_01857 582744.Msip34_1907 8.4e-183 646.4 Nitrosomonadales dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 ko:K03686 ko00000,ko03029,ko03110 Bacteria 1MVMS@1224,2KKPJ@206350,2VHEH@28216,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins HFDCGJPN_01858 1132855.KB913035_gene71 1.2e-261 908.7 Nitrosomonadales gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 1MVV8@1224,2KNIB@206350,2VI62@28216,COG0362@1,COG0362@2 NA|NA|NA G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH HFDCGJPN_01860 485913.Krac_0520 2.8e-46 193.0 Chloroflexi cypA ko:K15468 ko00000,ko01008 Bacteria 2G86W@200795,COG2124@1,COG2124@2 NA|NA|NA C SPTR A9AXU5 Cytochrome P450 HFDCGJPN_01861 207954.MED92_02249 1.5e-104 386.7 Oceanospirillales 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1MV1W@1224,1T9JH@1236,1XM8Q@135619,COG1541@1,COG1541@2 NA|NA|NA H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) HFDCGJPN_01862 395494.Galf_0017 2e-24 119.4 Betaproteobacteria Bacteria 1R9ZT@1224,2VPPS@28216,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor HFDCGJPN_01863 395494.Galf_0016 4.6e-97 362.1 Betaproteobacteria glnL ko:K07719 ko02020,map02020 M00518 ko00000,ko00001,ko00002,ko02022 Bacteria 1NNCT@1224,2VK0Z@28216,COG0457@1,COG0457@2,COG0784@1,COG0784@2 NA|NA|NA T Response regulator receiver HFDCGJPN_01864 583345.Mmol_1746 9.4e-57 226.1 Nitrosomonadales gloA 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1RCYX@1224,2KMSF@206350,2VR7R@28216,COG0346@1,COG0346@2 NA|NA|NA E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione HFDCGJPN_01865 62928.azo0761 1.2e-36 158.7 Rhodocyclales fdx1 ko:K03522,ko:K05337 ko00000,ko04147 Bacteria 1MZ6H@1224,2KX13@206389,2VTZ1@28216,COG1145@1,COG1145@2 NA|NA|NA C Ferredoxin HFDCGJPN_01866 582744.Msip34_1919 1.5e-62 245.7 Nitrosomonadales coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1RD9F@1224,2KMQ5@206350,2VMQQ@28216,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate HFDCGJPN_01867 265072.Mfla_0736 5.6e-44 183.7 Nitrosomonadales rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1MXKW@1224,2KMSC@206350,2VRD3@28216,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 HFDCGJPN_01868 582744.Msip34_1921 3.4e-167 594.7 Nitrosomonadales MA20_05660 ko:K07263 ko00000,ko01000,ko01002 Bacteria 1MU6R@1224,2KM4Y@206350,2VH8D@28216,COG0612@1,COG0612@2 NA|NA|NA S PFAM peptidase M16 domain protein HFDCGJPN_01869 582744.Msip34_1922 2.3e-203 714.9 Nitrosomonadales MA20_05655 ko:K07263 ko00000,ko01000,ko01002 Bacteria 1MVST@1224,2KKDQ@206350,2VHVB@28216,COG0612@1,COG0612@2 NA|NA|NA S Belongs to the peptidase M16 family HFDCGJPN_01870 582744.Msip34_1923 1.1e-143 516.2 Nitrosomonadales ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1MUDU@1224,2KKEC@206350,2VHK7@28216,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components HFDCGJPN_01871 265072.Mfla_0732 9.4e-94 349.7 Nitrosomonadales ftsE GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1MVQ4@1224,2KKZI@206350,2VINI@28216,COG2884@1,COG2884@2 NA|NA|NA D TIGRFAM cell division ATP-binding protein FtsE HFDCGJPN_01872 265072.Mfla_0731 1.5e-92 346.3 Nitrosomonadales ftsX GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1MU65@1224,2KMF3@206350,2VNGX@28216,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in cellular division HFDCGJPN_01873 1163617.SCD_n01454 2.6e-38 166.0 Betaproteobacteria fimV ko:K08086,ko:K09991 ko00000 Bacteria 1RGYW@1224,2VSW1@28216,COG3827@1,COG3827@2 NA|NA|NA HFDCGJPN_01874 1117958.PE143B_0127485 2.7e-87 329.3 Proteobacteria Bacteria 1NC0C@1224,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase HFDCGJPN_01876 1115515.EV102420_02_00090 7.1e-64 251.1 Gammaproteobacteria Bacteria 1R9PM@1224,1S0BV@1236,COG1100@1,COG1100@2 NA|NA|NA S Small GTP-binding protein HFDCGJPN_01877 216595.PFLU_1881A 4.3e-54 218.4 Bacteria Bacteria 2A3QZ@1,30S8P@2 NA|NA|NA HFDCGJPN_01878 667015.Bacsa_1144 5.9e-09 70.1 Bacteroidaceae Bacteria 2ER46@1,2FS2A@200643,33IPR@2,4ASYE@815,4PFE4@976 NA|NA|NA HFDCGJPN_01880 349521.HCH_00913 3.1e-109 401.4 Oceanospirillales Bacteria 1PK2S@1224,1S338@1236,1XQ9R@135619,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase superfamily HFDCGJPN_01881 266264.Rmet_1902 4.8e-56 224.6 Burkholderiaceae yebB Bacteria 1K7PR@119060,1PUT6@1224,28IT1@1,2VTT1@28216,2Z8S1@2 NA|NA|NA S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family HFDCGJPN_01882 196367.JNFG01000009_gene6316 1.8e-64 252.7 Burkholderiaceae ko:K07727 ko00000,ko03000 Bacteria 1K2US@119060,1RBPK@1224,2VIYU@28216,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain HFDCGJPN_01883 666681.M301_0991 2.1e-92 345.9 Nitrosomonadales 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1NERQ@1224,2KKSV@206350,2W0JI@28216,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain HFDCGJPN_01884 666681.M301_2225 1.3e-155 555.8 Nitrosomonadales tauA ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MVJA@1224,2KMIR@206350,2VNH6@28216,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family HFDCGJPN_01885 666681.M301_2224 1.1e-154 552.7 Nitrosomonadales ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MWDJ@1224,2KM22@206350,2VMK8@28216,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component HFDCGJPN_01886 666681.M301_2223 1.2e-139 502.7 Nitrosomonadales ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1MUDV@1224,2KKED@206350,2VMYS@28216,COG1116@1,COG1116@2 NA|NA|NA P ABC transporter HFDCGJPN_01888 1485544.JQKP01000001_gene898 6.6e-198 696.8 Nitrosomonadales glnT 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1MUGQ@1224,2VJ0X@28216,44WCI@713636,COG0174@1,COG0174@2 NA|NA|NA E Glutamine synthetase, catalytic domain HFDCGJPN_01889 582744.Msip34_0951 4.9e-115 420.6 Nitrosomonadales IV02_09290 ko:K09967 ko00000 Bacteria 1N2KR@1224,2KNG0@206350,2VKVN@28216,COG3665@1,COG3665@2 NA|NA|NA S TIGRFAM urea carboxylase-associated protein 2 HFDCGJPN_01890 582744.Msip34_0016 5.1e-119 433.7 Nitrosomonadales 1.1.2.7 ko:K14028 ko00010,ko00625,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00625,map00680,map01100,map01110,map01120,map01130,map01200 M00174 R01146,R09127,R09128,R10713 RC00034,RC00050,RC00087,RC00088 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUQX@1224,2KKUA@206350,2VHVH@28216,COG4993@1,COG4993@2 NA|NA|NA G TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family HFDCGJPN_01891 582744.Msip34_2750 3.7e-113 414.8 Nitrosomonadales 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1RG0B@1224,2KM6U@206350,2WBQE@28216,COG0265@1,COG0265@2,COG0457@1,COG0457@2 NA|NA|NA O Trypsin-like peptidase domain HFDCGJPN_01892 1116472.MGMO_10c00190 1.3e-100 372.9 Methylococcales 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1QGX4@1224,1RRS1@1236,1XEHN@135618,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase HFDCGJPN_01893 323261.Noc_1756 1.6e-104 386.3 Chromatiales Bacteria 1R5EN@1224,1T3Z7@1236,1X2QD@135613,COG4251@1,COG4251@2,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain HFDCGJPN_01894 857087.Metme_3902 1.8e-45 188.7 Methylococcales ko:K02485 ko00000,ko02022 Bacteria 1QUN7@1224,1T3Z8@1236,1XGIJ@135618,COG0784@1,COG0784@2 NA|NA|NA T SMART Signal transduction response regulator, receiver region HFDCGJPN_01896 582744.Msip34_2528 9.6e-91 339.7 Nitrosomonadales pyrE GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186 Bacteria 1MW6F@1224,2KM5T@206350,2VH9U@28216,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) HFDCGJPN_01897 582744.Msip34_2527 7.3e-125 453.4 Nitrosomonadales exoA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVII@1224,2KKGT@206350,2VI74@28216,COG0708@1,COG0708@2 NA|NA|NA L PFAM Endonuclease Exonuclease phosphatase HFDCGJPN_01898 857087.Metme_0997 3.3e-83 316.2 Gammaproteobacteria Bacteria 1R7HC@1224,1RXC9@1236,COG2199@1,COG2202@1,COG2202@2,COG3706@2 NA|NA|NA T PAS fold HFDCGJPN_01899 666681.M301_2592 1.6e-55 223.0 Nitrosomonadales Bacteria 1MW6R@1224,2KMZR@206350,2VSC6@28216,COG5429@1,COG5429@2 NA|NA|NA S Protein of unknown function (DUF1223) HFDCGJPN_01900 582744.Msip34_2526 5e-192 677.2 Nitrosomonadales ampG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria 1MUZ8@1224,2KM19@206350,2VI8P@28216,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily HFDCGJPN_01901 582744.Msip34_2525 6.9e-84 317.0 Nitrosomonadales braZ ko:K09792 ko00000 Bacteria 1RIGJ@1224,2KP5N@206350,2VINE@28216,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome C biogenesis protein transmembrane region HFDCGJPN_01902 666681.M301_2590 2.2e-79 302.0 Nitrosomonadales metW 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 1MVSY@1224,2KKRF@206350,2VMPA@28216,COG0500@1,COG2226@2 NA|NA|NA Q TIGRFAM methionine biosynthesis protein MetW HFDCGJPN_01903 1502770.JQMG01000001_gene724 8.8e-188 662.9 Nitrosomonadales metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 1MVJV@1224,2KKVG@206350,2VHU9@28216,COG2021@1,COG2021@2 NA|NA|NA E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine HFDCGJPN_01904 582744.Msip34_2522 3e-72 278.1 Nitrosomonadales yrdA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 ko:K08699 ko00000 Bacteria 1RD76@1224,2KMKC@206350,2VR65@28216,COG0663@1,COG0663@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) HFDCGJPN_01905 522306.CAP2UW1_2728 9.6e-55 219.9 unclassified Betaproteobacteria pagP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009279,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016409,GO:0016416,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044462,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.251 ko:K12973 ko01503,ko05133,map01503,map05133 M00724 R11223 RC00037,RC00041 ko00000,ko00001,ko00002,ko01000,ko01005 iEC042_1314.EC042_0658,iECO111_1330.ECO111_0653,iECSE_1348.ECSE_0690,iEcolC_1368.EcolC_3022 Bacteria 1KQWM@119066,1Q75P@1224,2C256@1,2VUK3@28216,2Z7SY@2 NA|NA|NA M Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors HFDCGJPN_01906 1165096.ARWF01000001_gene1811 1e-87 330.1 Nitrosomonadales prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 ko:K02493,ko:K02835 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 1MXCQ@1224,2KM69@206350,2VP72@28216,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif HFDCGJPN_01907 582744.Msip34_2518 2.7e-186 657.9 Nitrosomonadales prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02835,ko:K15034 ko00000,ko03012 Bacteria 1MV28@1224,2KMB9@206350,2VJKV@28216,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA HFDCGJPN_01908 582744.Msip34_2517 1.7e-192 678.7 Nitrosomonadales hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009288,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042597,GO:0042802,GO:0042995,GO:0043226,GO:0043228,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055040,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02407,ko:K02492 ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000,ko02035 iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iSB619.SA_RS08420,iUTI89_1310.UTI89_C1404 Bacteria 1MU41@1224,2KKTU@206350,2VHNC@28216,COG0373@1,COG0373@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) HFDCGJPN_01909 59538.XP_005976937.1 1.5e-116 425.6 Mammalia Mammalia 38G6J@33154,3BBFI@33208,3CTKR@33213,3JE6P@40674,48BUF@7711,490Q7@7742,COG0036@1,KOG3111@2759 NA|NA|NA G ribulose-phosphate 3-epimerase activity HFDCGJPN_01910 395494.Galf_2700 4.5e-23 114.4 Nitrosomonadales Bacteria 1PJX3@1224,2BUWK@1,2W88W@28216,32Q8Q@2,44WK2@713636 NA|NA|NA HFDCGJPN_01911 582744.Msip34_2515 4.9e-70 271.2 Nitrosomonadales gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.105,3.1.3.18 ko:K01091,ko:K22292 ko00520,ko00630,ko01100,ko01110,ko01130,map00520,map00630,map01100,map01110,map01130 R01334,R11785 RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 Bacteria 1RDDY@1224,2KMQB@206350,2VIZ6@28216,COG0546@1,COG0546@2 NA|NA|NA G subfamily IA, variant 1 HFDCGJPN_01912 1502770.JQMG01000001_gene717 6.6e-231 806.6 Nitrosomonadales trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0417 Bacteria 1MVBJ@1224,2KKDB@206350,2VI2V@28216,COG0147@1,COG0147@2 NA|NA|NA E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia HFDCGJPN_01913 1101195.Meth11DRAFT_2509 5.5e-98 363.6 Nitrosomonadales trpG 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV5Y@1224,2KMC5@206350,2VHGQ@28216,COG0512@1,COG0512@2 NA|NA|NA EH TIGRFAM glutamine amidotransferase of anthranilate synthase HFDCGJPN_01915 582744.Msip34_1315 3.8e-72 277.3 Nitrosomonadales queF 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 R07605 RC01875 ko00000,ko00001,ko01000,ko03016 Bacteria 1MW0M@1224,2KMK5@206350,2VINU@28216,COG0780@1,COG0780@2 NA|NA|NA S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) HFDCGJPN_01916 582744.Msip34_1316 4.3e-286 991.1 Nitrosomonadales smc ko:K03529 ko00000,ko03036 Bacteria 1MUAQ@1224,2KKSR@206350,2VJMF@28216,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning HFDCGJPN_01917 265072.Mfla_1402 1.8e-105 389.8 Nitrosomonadales zipA ko:K03528 ko00000,ko03036 Bacteria 1NJ6D@1224,2KKSC@206350,2VHQ7@28216,COG3115@1,COG3115@2 NA|NA|NA D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins HFDCGJPN_01918 582744.Msip34_1318 3.3e-289 1000.7 Nitrosomonadales ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 Bacteria 1MV3R@1224,2KMEH@206350,2VIDE@28216,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA HFDCGJPN_01919 582744.Msip34_1319 3.7e-87 328.2 Nitrosomonadales cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0008934,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019637,GO:0019693,GO:0030145,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050308,GO:0050427,GO:0050897,GO:0052745,GO:0052834,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1N0GY@1224,2KMET@206350,2VJWH@28216,COG1218@1,COG1218@2 NA|NA|NA P Inositol monophosphatase family HFDCGJPN_01920 582744.Msip34_1320 9.1e-55 220.7 Nitrosomonadales Bacteria 1NB06@1224,2KN0Z@206350,2W6GC@28216,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeats HFDCGJPN_01921 582744.Msip34_1321 1.5e-143 515.8 Nitrosomonadales msrP ko:K07147 ko00000,ko01000 Bacteria 1MUW0@1224,2KKE6@206350,2VH08@28216,COG2041@1,COG2041@2 NA|NA|NA C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide HFDCGJPN_01922 666681.M301_1375 1.8e-75 288.9 Nitrosomonadales msrQ ko:K17247 ko00000 Bacteria 1RDUP@1224,2KMMD@206350,2VRBQ@28216,COG2717@1,COG2717@2 NA|NA|NA C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain HFDCGJPN_01923 666681.M301_1374 6.5e-58 230.3 Nitrosomonadales ko:K15977 ko00000 Bacteria 1RM2W@1224,2KMYZ@206350,2VWVB@28216,COG2259@1,COG2259@2 NA|NA|NA S PFAM DoxX family protein HFDCGJPN_01924 265072.Mfla_1406 2.4e-84 318.5 Nitrosomonadales cmpX Bacteria 1N2GE@1224,2KM1E@206350,2VUZW@28216,COG0668@1,COG0668@2 NA|NA|NA M PFAM Conserved TM helix HFDCGJPN_01925 1123393.KB891316_gene1935 3.8e-51 209.9 Betaproteobacteria Bacteria 1MU2C@1224,2VH3V@28216,COG5001@1,COG5001@2 NA|NA|NA T Diguanylate cyclase HFDCGJPN_01926 666681.M301_0165 4.3e-43 181.0 Nitrosomonadales cobC 2.6.1.9,4.1.1.81 ko:K00817,ko:K02225,ko:K04720 ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230 M00026,M00122 R00694,R00734,R03243,R06529,R06530,R07302 RC00006,RC00090,RC00096,RC00517,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MXDP@1224,2KKQ8@206350,2VKTS@28216,COG0079@1,COG0079@2 NA|NA|NA E PFAM Aminotransferase class I and II HFDCGJPN_01927 265072.Mfla_0100 4.3e-50 204.5 Nitrosomonadales gpmB 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1N14H@1224,2KMZ9@206350,2VU12@28216,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family HFDCGJPN_01928 666681.M301_0163 6.4e-78 297.4 Nitrosomonadales cobS GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1RHCC@1224,2KM2D@206350,2VS93@28216,COG0368@1,COG0368@2 NA|NA|NA H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate HFDCGJPN_01929 1132855.KB913035_gene2590 4.1e-131 474.6 Nitrosomonadales cobT GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 ko:K00768 ko00860,ko01100,map00860,map01100 M00122 R04148 RC00033,RC00063 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVAM@1224,2KKVN@206350,2VJTR@28216,COG2038@1,COG2038@2 NA|NA|NA H Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) HFDCGJPN_01931 666681.M301_0160 3.2e-34 151.0 Nitrosomonadales Bacteria 1PEUP@1224,2KN6X@206350,2WAFD@28216,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain HFDCGJPN_01932 582744.Msip34_0094 2e-28 131.3 Nitrosomonadales tusA ko:K04085 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Bacteria 1MZA5@1224,2KNBD@206350,2VVW5@28216,COG0425@1,COG0425@2 NA|NA|NA O Belongs to the sulfur carrier protein TusA family HFDCGJPN_01933 1038862.KB893857_gene6791 1.3e-108 399.4 Bradyrhizobiaceae Bacteria 1MUCH@1224,2TQRM@28211,3JVZ4@41294,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase HFDCGJPN_01934 1538295.JY96_09470 4.1e-51 208.0 unclassified Burkholderiales ko:K16137 ko00000,ko03000 Bacteria 1KMH5@119065,1N1Q3@1224,2W9VG@28216,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family HFDCGJPN_01935 1502770.JQMG01000001_gene57 1e-17 95.5 Nitrosomonadales bfd ko:K00360,ko:K02192 ko00910,ko01120,map00910,map01120 M00531 R00798 RC02812 ko00000,ko00001,ko00002,ko01000 Bacteria 1NJSX@1224,2KNC7@206350,2W6K6@28216,COG1251@1,COG1251@2 NA|NA|NA C PFAM BFD domain protein 2Fe-2S -binding domain protein HFDCGJPN_01936 1132855.KB913035_gene1356 6.9e-122 443.7 Nitrosomonadales ko:K16259 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1MX8R@1224,2KMFJ@206350,2VPW9@28216,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain HFDCGJPN_01937 1502770.JQMG01000001_gene1922 8.7e-67 259.6 Nitrosomonadales Bacteria 1RFH5@1224,29IZA@1,2KMSX@206350,2W7Z1@28216,305WS@2 NA|NA|NA HFDCGJPN_01938 1502770.JQMG01000001_gene1923 4.9e-121 441.0 Nitrosomonadales nphR Bacteria 1MXT9@1224,2KKXZ@206350,2VK2J@28216,COG2207@1,COG2207@2 NA|NA|NA K AraC-binding-like domain HFDCGJPN_01939 582744.Msip34_0477 1.2e-41 176.0 Betaproteobacteria ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1N1RF@1224,2VT18@28216,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family HFDCGJPN_01940 582744.Msip34_0092 0.0 1689.1 Nitrosomonadales valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Bacteria 1MV7B@1224,2KMDC@206350,2VH5Z@28216,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner HFDCGJPN_01941 265072.Mfla_0090 1.4e-76 293.1 Nitrosomonadales Bacteria 1QV1U@1224,2DKZI@1,2KP95@206350,2VQ0G@28216,310D6@2 NA|NA|NA HFDCGJPN_01942 1236959.BAMT01000006_gene260 1.4e-69 269.2 Nitrosomonadales lemA ko:K03744 ko00000 Bacteria 1R9YG@1224,2KNHA@206350,2VQ2A@28216,COG1704@1,COG1704@2 NA|NA|NA S LemA family HFDCGJPN_01943 666681.M301_0154 5.4e-45 187.2 Nitrosomonadales ko:K07340 ko00000 Bacteria 1N4FG@1224,2KN1A@206350,2VTGB@28216,COG1585@1,COG1585@2 NA|NA|NA OU NfeD-like C-terminal, partner-binding HFDCGJPN_01944 265072.Mfla_0086 1.9e-99 369.0 Nitrosomonadales hflC Bacteria 1MUM8@1224,2KMA2@206350,2VHBD@28216,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues HFDCGJPN_01945 582744.Msip34_1047 8.1e-16 89.0 Nitrosomonadales Bacteria 1Q7EI@1224,2EGMT@1,2KN8J@206350,2VZ0N@28216,31BJK@2 NA|NA|NA S Phospholipase_D-nuclease N-terminal HFDCGJPN_01946 1165096.ARWF01000001_gene1412 2.4e-97 361.7 Nitrosomonadales moeB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000 iECIAI1_1343.ECIAI1_0865,iECW_1372.ECW_m0884,iEKO11_1354.EKO11_3059,iETEC_1333.ETEC_0893,iEcE24377_1341.EcE24377A_0897,iEcSMS35_1347.EcSMS35_0851,iWFL_1372.ECW_m0884 Bacteria 1MW7H@1224,2KKRE@206350,2VI1U@28216,COG0476@1,COG0476@2 NA|NA|NA H PFAM UBA THIF-type NAD FAD binding protein HFDCGJPN_01948 265072.Mfla_2087 1.7e-89 335.9 Nitrosomonadales kdsB 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MUUU@1224,2KKCN@206350,2VINM@28216,COG1212@1,COG1212@2 NA|NA|NA M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria HFDCGJPN_01949 265072.Mfla_2088 1e-21 108.6 Nitrosomonadales ycaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 ko:K00912,ko:K09791 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1N6Y2@1224,2KNA4@206350,2VW58@28216,COG2835@1,COG2835@2 NA|NA|NA S Belongs to the UPF0434 family HFDCGJPN_01950 583345.Mmol_0649 4.6e-92 344.7 Nitrosomonadales lpxK 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1MU8G@1224,2KKX0@206350,2VHPG@28216,COG1663@1,COG1663@2 NA|NA|NA M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) HFDCGJPN_01951 582744.Msip34_0639 5.1e-235 820.5 Nitrosomonadales msbA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02021,ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980 Bacteria 1MUBM@1224,2KMBG@206350,2VHAN@28216,COG1132@1,COG1132@2 NA|NA|NA V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation HFDCGJPN_01952 582744.Msip34_0638 1.3e-56 225.7 Nitrosomonadales exbD2 ko:K03559,ko:K03560 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1N0ZA@1224,2KMSH@206350,2VUF4@28216,COG0848@1,COG0848@2 NA|NA|NA U PFAM Biopolymer transport protein ExbD TolR HFDCGJPN_01953 582744.Msip34_0637 1.4e-91 342.4 Nitrosomonadales exbB2 ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1QNJ1@1224,2KMAP@206350,2VITY@28216,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel HFDCGJPN_01954 1163617.SCD_n01103 8.8e-246 856.7 Betaproteobacteria ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1MUKF@1224,2VHKP@28216,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S DNA internalization-related competence protein ComEC Rec2 HFDCGJPN_01955 1236959.BAMT01000002_gene2317 2.7e-91 341.7 Nitrosomonadales lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043167,GO:0043168,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351,GO:1990778 ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 1MVSQ@1224,2KMB3@206350,2VHAQ@28216,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner HFDCGJPN_01956 265072.Mfla_2095 1.1e-183 649.4 Nitrosomonadales lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 1MVV7@1224,2KKB0@206350,2VH7C@28216,COG4591@1,COG4591@2 NA|NA|NA M TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family HFDCGJPN_01957 582744.Msip34_0632 8.1e-79 300.1 Nitrosomonadales ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 1MUMB@1224,2KMNG@206350,2VIU0@28216,COG0307@1,COG0307@2 NA|NA|NA H TIGRFAM riboflavin synthase, alpha subunit HFDCGJPN_01958 582744.Msip34_0631 5.1e-156 557.4 Nitrosomonadales ribB 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU8P@1224,2KKS1@206350,2VH6S@28216,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate HFDCGJPN_01959 582744.Msip34_0630 3.3e-60 238.0 Nitrosomonadales yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07735 ko00000,ko03000 Bacteria 1RCXM@1224,2KMR8@206350,2VJQA@28216,COG1678@1,COG1678@2 NA|NA|NA K Belongs to the UPF0301 (AlgH) family HFDCGJPN_01960 582744.Msip34_0629 6.3e-53 213.8 Nitrosomonadales yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1RDHZ@1224,2KN0K@206350,2VUH0@28216,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA HFDCGJPN_01961 265072.Mfla_2101 9.2e-60 236.5 Nitrosomonadales pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1RI6U@1224,2KMVB@206350,2VSNM@28216,COG2065@1,COG2065@2 NA|NA|NA F Phosphoribosyl transferase domain HFDCGJPN_01962 582744.Msip34_0627 3.8e-160 570.9 Nitrosomonadales pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1MWAB@1224,2KM77@206350,2VHG9@28216,COG0540@1,COG0540@2 NA|NA|NA F aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain HFDCGJPN_01963 582744.Msip34_0626 8.7e-184 649.8 Nitrosomonadales pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVXY@1224,2KKJ0@206350,2VH1E@28216,COG0044@1,COG0044@2 NA|NA|NA F TIGRFAM dihydroorotase, multifunctional complex type HFDCGJPN_01964 572480.Arnit_3033 3e-20 105.5 Epsilonproteobacteria Bacteria 1RIIU@1224,2B96M@1,2YRX1@29547,322HU@2,4301T@68525 NA|NA|NA HFDCGJPN_01965 1165096.ARWF01000001_gene2241 6.4e-186 656.8 Nitrosomonadales pilU ko:K02670 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1QTTX@1224,2KKV0@206350,2VIWS@28216,COG5008@1,COG5008@2 NA|NA|NA NU PFAM type II secretion system protein E HFDCGJPN_01966 582744.Msip34_0623 6.2e-180 636.7 Nitrosomonadales pilT ko:K02669 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1MU3J@1224,2KKFY@206350,2VHHW@28216,COG2805@1,COG2805@2 NA|NA|NA NU PFAM type II secretion system protein E HFDCGJPN_01967 265072.Mfla_2108 7.1e-74 283.9 Nitrosomonadales yggS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 ko:K06997 ko00000 Bacteria 1MWN7@1224,2KKJ3@206350,2VHNY@28216,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis HFDCGJPN_01968 582744.Msip34_0621 9.3e-96 356.7 Nitrosomonadales proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1R5J1@1224,2KKDT@206350,2VJD1@28216,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline HFDCGJPN_01969 265072.Mfla_2110 9.3e-61 240.0 Nitrosomonadales yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1RCZV@1224,2KMRR@206350,2VRHV@28216,COG0762@1,COG0762@2 NA|NA|NA S YGGT family HFDCGJPN_01970 1132855.KB913035_gene2211 4.4e-187 661.4 Nitrosomonadales Bacteria 1MXBK@1224,2KNGS@206350,2W1AV@28216,COG0699@1,COG0699@2 NA|NA|NA S Dynamin family HFDCGJPN_01971 582744.Msip34_0619 3.8e-228 797.3 Nitrosomonadales rng GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K08301 ko00000,ko01000,ko03009,ko03019 Bacteria 1MV65@1224,2KM8H@206350,2VI3N@28216,COG1530@1,COG1530@2 NA|NA|NA J TIGRFAM ribonuclease, Rne Rng family HFDCGJPN_01972 3988.XP_002537144.1 2.3e-59 235.3 Streptophyta ko:K06287 ko00000 Viridiplantae 37UIQ@33090,3GKBA@35493,COG0424@1,KOG1509@2759 NA|NA|NA D Maf-like protein HFDCGJPN_01973 582744.Msip34_0616 6.1e-85 320.5 Nitrosomonadales marC ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1MX5T@1224,2KKWH@206350,2VIBH@28216,COG2095@1,COG2095@2 NA|NA|NA U PFAM multiple antibiotic resistance (MarC)-related protein HFDCGJPN_01974 582744.Msip34_0615 6.3e-57 226.9 Nitrosomonadales nudJ GO:0003674,GO:0003824,GO:0004787,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0017111 3.6.1.55 ko:K03574,ko:K12152 ko00000,ko01000,ko03400 iSbBS512_1146.SbBS512_E1312 Bacteria 1N03W@1224,2KMQH@206350,2VRC0@28216,COG1051@1,COG1051@2 NA|NA|NA F Belongs to the Nudix hydrolase family. NudJ subfamily HFDCGJPN_01975 265072.Mfla_2115 1.9e-184 651.7 Nitrosomonadales mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1MUT1@1224,2KM9V@206350,2VJRR@28216,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 HFDCGJPN_01976 582744.Msip34_0612 5e-81 307.4 Nitrosomonadales yibF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1RHSK@1224,2KM98@206350,2VIJ5@28216,COG0625@1,COG0625@2 NA|NA|NA O PFAM Glutathione S-transferase HFDCGJPN_01977 582744.Msip34_0611 2.9e-98 365.2 Nitrosomonadales nadC 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW0C@1224,2KMJE@206350,2VHSU@28216,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family HFDCGJPN_01978 582744.Msip34_0610 1.6e-276 958.4 Nitrosomonadales gspE ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MU7V@1224,2KKDI@206350,2VHQ1@28216,COG2804@1,COG2804@2 NA|NA|NA NU General secretory system II protein E domain protein HFDCGJPN_01979 582744.Msip34_0609 4.2e-298 1030.0 Nitrosomonadales ilvI GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082 Bacteria 1MU6U@1224,2KM1K@206350,2VJ55@28216,COG0028@1,COG0028@2 NA|NA|NA E TIGRFAM acetolactate synthase, large subunit, biosynthetic type HFDCGJPN_01980 582744.Msip34_0608 2.9e-79 301.2 Nitrosomonadales ilvH GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1906,iECNA114_1301.ECNA114_0072,iEcSMS35_1347.EcSMS35_0084,iG2583_1286.G2583_0082,iSFxv_1172.SFxv_0077,iUTI89_1310.UTI89_C0086 Bacteria 1RAGN@1224,2KMDF@206350,2VH1H@28216,COG0440@1,COG0440@2 NA|NA|NA E TIGRFAM acetolactate synthase, small subunit HFDCGJPN_01981 265072.Mfla_2121 1e-171 609.4 Nitrosomonadales ilvC 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iJN746.PP_4678,iLJ478.TM0550 Bacteria 1MV7M@1224,2KMD7@206350,2VIQ5@28216,COG0059@1,COG0059@2 NA|NA|NA EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate HFDCGJPN_01982 1304883.KI912532_gene2041 2.3e-111 408.7 Rhodocyclales psd GO:0003674,GO:0003824,GO:0004609,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4379,iECSF_1327.ECSF_4049 Bacteria 1MVT4@1224,2KUHW@206389,2VJCQ@28216,COG0688@1,COG0688@2 NA|NA|NA I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) HFDCGJPN_01983 582744.Msip34_0605 4.4e-84 317.4 Nitrosomonadales nudH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 ko:K08311 ko03018,map03018 R10816 RC00002 ko00000,ko00001,ko01000,ko03019 Bacteria 1RDGJ@1224,2KKCG@206350,2VIDX@28216,COG0494@1,COG0494@2 NA|NA|NA L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage HFDCGJPN_01985 582744.Msip34_0603 1.1e-81 309.3 Nitrosomonadales ko:K16260 ko00680,ko01120,map00680,map01120 ko00000,ko00001 Bacteria 1RD9A@1224,2KMT1@206350,2VQDY@28216,COG3832@1,COG3832@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport HFDCGJPN_01986 153948.NAL212_2190 2e-26 125.6 Nitrosomonadales pilA ko:K02650,ko:K02682 ko02020,map02020 ko00000,ko00001,ko02035,ko02044 3.A.15.2 Bacteria 1N7EQ@1224,2VVSJ@28216,373N1@32003,COG4969@1,COG4969@2 NA|NA|NA NU Belongs to the N-Me-Phe pilin family HFDCGJPN_01987 292415.Tbd_2199 8.7e-46 191.8 Betaproteobacteria Bacteria 1NFQW@1224,2VQUC@28216,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide TPR_2 repeat protein HFDCGJPN_01988 666681.M301_0621 1.8e-121 442.6 Nitrosomonadales Bacteria 1R9Q1@1224,2KNP5@206350,2VQGZ@28216,COG0607@1,COG0607@2,COG2905@1,COG2905@2 NA|NA|NA PT Cyclic nucleotide-monophosphate binding domain HFDCGJPN_01989 666681.M301_0620 1.2e-87 329.7 Nitrosomonadales 3.1.26.11,3.1.4.17 ko:K00784,ko:K01120 ko00230,ko03013,map00230,map03013 R00191,R01234 RC00296 ko00000,ko00001,ko01000,ko03016 Bacteria 1QU4B@1224,2KMHV@206350,2VH0D@28216,COG1234@1,COG1234@2 NA|NA|NA S cAMP phosphodiesterases class-II HFDCGJPN_01990 580332.Slit_0533 1e-240 839.7 Betaproteobacteria cyaA 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1V@1224,2VJ72@28216,COG2114@1,COG2114@2,COG4252@1,COG4252@2 NA|NA|NA T Adenylyl cyclase class-3 4 guanylyl cyclase HFDCGJPN_01991 1101195.Meth11DRAFT_0676 1.1e-63 250.0 Nitrosomonadales estB ko:K06999 ko00000 Bacteria 1RA02@1224,2KMM3@206350,2VJ6G@28216,COG0400@1,COG0400@2 NA|NA|NA S PFAM phospholipase Carboxylesterase HFDCGJPN_01992 265072.Mfla_2131 3.4e-15 87.4 Nitrosomonadales xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1PTYP@1224,2KN7U@206350,2VVQV@28216,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides HFDCGJPN_01993 582744.Msip34_0597 3.6e-120 438.0 Nitrosomonadales ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1MWNG@1224,2KKBC@206350,2VHQV@28216,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family HFDCGJPN_01994 582744.Msip34_0596 1.3e-302 1045.0 Nitrosomonadales dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUSJ@1224,2KKBR@206350,2VHXG@28216,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) HFDCGJPN_01995 582744.Msip34_0595 3.2e-131 474.6 Nitrosomonadales folE2 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV1B@1224,2KKMR@206350,2VIC9@28216,COG1469@1,COG1469@2 NA|NA|NA S Converts GTP to 7,8-dihydroneopterin triphosphate HFDCGJPN_01996 582744.Msip34_0594 1e-58 233.4 Nitrosomonadales ko:K06985 ko04112,map04112 ko00000,ko00001 Bacteria 1N2PE@1224,2KMNB@206350,2VS6Z@28216,COG3577@1,COG3577@2 NA|NA|NA S gag-polyprotein putative aspartyl protease HFDCGJPN_01997 582744.Msip34_0593 6.9e-164 583.6 Nitrosomonadales ko:K05820,ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25,2.A.1.27 Bacteria 1QY3E@1224,2KPAA@206350,2WHA2@28216,COG2211@1,COG2211@2 NA|NA|NA G Nucleoside H+ symporter HFDCGJPN_01998 1101195.Meth11DRAFT_0669 6.5e-188 663.3 Nitrosomonadales aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iIT341.HP0663,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Bacteria 1MU98@1224,2KKJ8@206350,2VJA4@28216,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system HFDCGJPN_01999 1101195.Meth11DRAFT_0668 2.1e-94 352.1 Nitrosomonadales Bacteria 1MUDH@1224,2KKPM@206350,2VJEI@28216,COG0518@1,COG0518@2 NA|NA|NA F PFAM Glutamine amidotransferase class-I HFDCGJPN_02000 582744.Msip34_0590 3.8e-77 294.3 Nitrosomonadales rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.20,5.4.99.22 ko:K06178,ko:K06181,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1R9VV@1224,2KKDS@206350,2VQAQ@28216,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family HFDCGJPN_02001 582744.Msip34_0589 2e-217 761.5 Nitrosomonadales icd GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 iJN746.PP_4011 Bacteria 1MW3J@1224,2KKC5@206350,2VHVD@28216,COG0538@1,COG0538@2 NA|NA|NA C PFAM isocitrate isopropylmalate dehydrogenase HFDCGJPN_02002 1236959.BAMT01000002_gene2261 2.7e-31 140.6 Nitrosomonadales scoF ko:K03704 ko00000,ko03000 Bacteria 1N6Q5@1224,2KN49@206350,2VVTG@28216,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein HFDCGJPN_02003 582744.Msip34_0587 3.5e-265 920.6 Nitrosomonadales pilB ko:K02652 ko00000,ko02035,ko02044 3.A.15.2 Bacteria 1MU7V@1224,2KKYV@206350,2VHQ1@28216,COG2804@1,COG2804@2 NA|NA|NA NU TIGRFAM type IV-A pilus assembly ATPase PilB HFDCGJPN_02004 265072.Mfla_2142 7.4e-193 679.9 Nitrosomonadales pilC GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 Bacteria 1MV4U@1224,2KKCS@206350,2VHPE@28216,COG1459@1,COG1459@2 NA|NA|NA NU PFAM type II secretion system HFDCGJPN_02005 1236959.BAMT01000002_gene2258 1.6e-97 362.5 Nitrosomonadales 5.3.4.1 ko:K03981 ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 Bacteria 1RD39@1224,2KKTR@206350,2VIHV@28216,COG1651@1,COG1651@2 NA|NA|NA O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process HFDCGJPN_02006 582744.Msip34_0584 5.9e-102 377.9 Nitrosomonadales ubiH ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU6I@1224,2KM0M@206350,2VIPS@28216,COG0654@1,COG0654@2 NA|NA|NA CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family HFDCGJPN_02007 265072.Mfla_2145 2.9e-146 525.0 Nitrosomonadales ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 ko:K03184,ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R06146,R08768,R08773,R08775 RC00046,RC01254,RC02670 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066 Bacteria 1MU6I@1224,2KKTI@206350,2VKV7@28216,COG0654@1,COG0654@2 NA|NA|NA CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family HFDCGJPN_02008 666681.M301_0598 1.6e-188 665.6 Nitrosomonadales pepP 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 1MUZS@1224,2KKCQ@206350,2VHQI@28216,COG0006@1,COG0006@2 NA|NA|NA E peptidase M24B X-Pro dipeptidase aminopeptidase domain protein HFDCGJPN_02009 666681.M301_0597 9.2e-84 316.6 Nitrosomonadales rmlA GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 ko:K00966,ko:K00973,ko:K00992 ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130 M00114,M00361,M00362,M00793 R00885,R02328,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1R9ZD@1224,2KMGT@206350,2VJUN@28216,COG1208@1,COG1208@2 NA|NA|NA JM PFAM Nucleotidyl transferase HFDCGJPN_02010 1101195.Meth11DRAFT_0656 4.9e-134 484.2 Nitrosomonadales GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1MXCH@1224,2KM5S@206350,2VHBC@28216,COG3178@1,COG3178@2 NA|NA|NA S Phosphotransferase enzyme family HFDCGJPN_02011 582744.Msip34_0579 0.0 1082.0 Nitrosomonadales lptD GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015075,GO:0015136,GO:0015144,GO:0015157,GO:0015267,GO:0015288,GO:0015318,GO:0015478,GO:0015711,GO:0015739,GO:0015772,GO:0015849,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0033036,GO:0034219,GO:0034220,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045203,GO:0045229,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1903825,GO:1905039 ko:K04744,ko:K22110 ko00000,ko02000 1.B.35.1,1.B.35.2,1.B.42.1 iG2583_1286.G2583_0058,ic_1306.c5389 Bacteria 1MUJC@1224,2KM3D@206350,2VIJ7@28216,COG1452@1,COG1452@2 NA|NA|NA M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane HFDCGJPN_02012 580332.Slit_0879 6.1e-192 677.6 Nitrosomonadales Bacteria 1MU2C@1224,2VH3V@28216,44W76@713636,COG2202@1,COG2202@2,COG3829@1,COG3829@2,COG5001@1,COG5001@2 NA|NA|NA T Putative diguanylate phosphodiesterase HFDCGJPN_02013 582744.Msip34_2626 1.1e-181 642.9 Nitrosomonadales ko:K07714 ko02020,map02020 M00500 ko00000,ko00001,ko00002,ko02022 Bacteria 1MU0N@1224,2KKBW@206350,2VHSB@28216,COG2204@1,COG2204@2 NA|NA|NA T PFAM sigma-54 factor interaction domain-containing protein HFDCGJPN_02014 582744.Msip34_2625 3.2e-186 658.3 Nitrosomonadales Bacteria 1NRP8@1224,2KPAV@206350,2WHYT@28216,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain HFDCGJPN_02015 582744.Msip34_2624 2.3e-115 422.2 Nitrosomonadales ko:K09476 ko01501,ko02020,map01501,map02020 M00746 ko00000,ko00001,ko00002,ko01504,ko02000 1.B.1.1.1 Bacteria 1R12R@1224,2KPAU@206350,2WHYS@28216,COG3203@1,COG3203@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane HFDCGJPN_02016 666681.M301_1909 2.6e-41 174.9 Nitrosomonadales Bacteria 1N3EC@1224,2KN1P@206350,2VXDA@28216,COG0226@1,COG0226@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import HFDCGJPN_02017 582744.Msip34_2622 1.5e-51 209.5 Nitrosomonadales Bacteria 1N2I4@1224,2CJ6B@1,2KMP7@206350,2VV7N@28216,32S9B@2 NA|NA|NA S Thermostable hemolysin HFDCGJPN_02018 666681.M301_1907 3.4e-150 538.5 Nitrosomonadales Bacteria 1MU4D@1224,2KM14@206350,2VN53@28216,COG1022@1,COG1022@2 NA|NA|NA I PFAM AMP-dependent synthetase and ligase HFDCGJPN_02019 582744.Msip34_2620 5.3e-92 344.0 Betaproteobacteria 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVA0@1224,2WGSW@28216,COG0819@1,COG0819@2 NA|NA|NA K Iron-containing redox enzyme HFDCGJPN_02020 582744.Msip34_2619 8.4e-84 317.0 Nitrosomonadales Bacteria 1RAFB@1224,2KMGC@206350,2VS3H@28216,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family HFDCGJPN_02021 666681.M301_1904 2.8e-82 311.6 Nitrosomonadales ko:K02656 ko00000,ko02035,ko02044 Bacteria 1RD9T@1224,2KMNU@206350,2VQ2E@28216,COG3063@1,COG3063@2 NA|NA|NA NU Tetratricopeptide repeat HFDCGJPN_02023 1165096.ARWF01000001_gene575 1.5e-52 212.2 Nitrosomonadales Bacteria 1N2WQ@1224,2DIKN@1,2KNUE@206350,2VVBM@28216,32UB8@2 NA|NA|NA HFDCGJPN_02024 1165096.ARWF01000001_gene576 2.1e-33 148.3 Nitrosomonadales copZ ko:K07213,ko:K08364 ko04978,map04978 ko00000,ko00001,ko02000 1.A.72.1 Bacteria 1N3D6@1224,2KNAT@206350,2VV1F@28216,COG2608@1,COG2608@2 NA|NA|NA P PFAM Heavy metal transport detoxification protein HFDCGJPN_02025 1165096.ARWF01000001_gene577 2.6e-94 351.7 Nitrosomonadales Bacteria 1RBV5@1224,28NQX@1,2KMZ4@206350,2VQ04@28216,2ZBQB@2 NA|NA|NA HFDCGJPN_02026 666681.M301_0101 5.1e-15 87.4 Nitrosomonadales Bacteria 1PJSA@1224,2A8U6@1,2KP02@206350,2W85I@28216,30XXD@2 NA|NA|NA HFDCGJPN_02027 1408424.JHYI01000010_gene852 1.7e-38 165.6 Bacillus Bacteria 1V6N8@1239,1ZH2H@1386,4HITB@91061,COG0454@1,COG0454@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases HFDCGJPN_02028 264198.Reut_A2711 1.1e-83 316.6 Burkholderiaceae hutG 3.5.1.68 ko:K01458 ko00340,ko00630,map00340,map00630 R00525 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1JZPU@119060,1MY4D@1224,2VK2Y@28216,COG3741@1,COG3741@2 NA|NA|NA E N-formylglutamate amidohydrolase HFDCGJPN_02029 1484158.PSNIH1_10775 9.4e-16 90.5 Pantoea ves ko:K09975 ko00000 Bacteria 1MXSD@1224,1RMHD@1236,3W0RM@53335,COG3758@1,COG3758@2 NA|NA|NA S HutD HFDCGJPN_02030 265072.Mfla_2364 8e-78 296.6 Nitrosomonadales Bacteria 1NMVA@1224,2KKKR@206350,2W0JG@28216,COG1795@1,COG1795@2 NA|NA|NA S Formaldehyde-activating enzyme (Fae) HFDCGJPN_02031 1158292.JPOE01000005_gene1060 2.9e-87 328.2 Betaproteobacteria Bacteria 1RDVJ@1224,2VHK1@28216,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family HFDCGJPN_02032 582744.Msip34_2464 1.1e-89 336.3 Nitrosomonadales narL GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 1NQH7@1224,2KP4A@206350,2VP8T@28216,COG2197@1,COG2197@2 NA|NA|NA K Winged helix-turn-helix DNA-binding HFDCGJPN_02033 582744.Msip34_2465 5.1e-177 627.9 Nitrosomonadales 2.7.13.3 ko:K07673,ko:K07675 ko02020,map02020 M00471,M00473 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1MWZT@1224,2KM4F@206350,2VR0M@28216,COG3850@1,COG3850@2 NA|NA|NA T Histidine kinase HFDCGJPN_02034 582744.Msip34_2466 4.8e-159 567.8 Nitrosomonadales Bacteria 1QXB5@1224,2KM85@206350,2VZW3@28216,COG2202@1,COG2202@2 NA|NA|NA T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) HFDCGJPN_02035 582744.Msip34_2467 2.9e-92 345.1 Nitrosomonadales Bacteria 1RK4D@1224,2C5U9@1,2KN4K@206350,2VKK4@28216,318BZ@2 NA|NA|NA S Bacterial protein of unknown function (Gcw_chp) HFDCGJPN_02036 582744.Msip34_2468 4.5e-162 577.4 Nitrosomonadales 1.14.13.238 ko:K22342 ko00000,ko01000 Bacteria 1N6CK@1224,2DB9X@1,2KMHB@206350,2VP3T@28216,2Z7ZS@2 NA|NA|NA S Protein of unknown function (DUF3445) HFDCGJPN_02037 666681.M301_1393 4.5e-137 494.2 Nitrosomonadales yeaX 1.14.13.238 ko:K22343 ko00000,ko01000 Bacteria 1MU6E@1224,2KKNF@206350,2VK6Y@28216,COG1018@1,COG1018@2 NA|NA|NA C Oxidoreductase NAD-binding domain HFDCGJPN_02038 666681.M301_1394 2.4e-67 261.9 Nitrosomonadales 1.14.13.238 ko:K22344 ko00000,ko01000 Bacteria 1N0PJ@1224,28IUB@1,2KMPE@206350,2VUS4@28216,2Z8T2@2 NA|NA|NA HFDCGJPN_02039 582744.Msip34_2471 4.4e-176 624.0 Nitrosomonadales 1.5.3.1,2.1.2.10 ko:K00302,ko:K00305,ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R00610,R01221,R02300,R04125 RC00022,RC00060,RC00069,RC00183,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV96@1224,2KM4B@206350,2VIT9@28216,COG0404@1,COG0404@2 NA|NA|NA E PFAM glycine cleavage T protein (aminomethyl transferase) HFDCGJPN_02040 358220.C380_11515 3e-73 282.7 Comamonadaceae yfiN GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032153,GO:0032879,GO:0033554,GO:0036460,GO:0040012,GO:0040013,GO:0042802,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0051271,GO:0051716,GO:0052621,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 ko:K21021 ko02025,map02025 ko00000,ko00001,ko01000 Bacteria 1RE33@1224,2VRWV@28216,4AE1D@80864,COG2199@1,COG2199@2,COG2202@1,COG2202@2,COG3706@2 NA|NA|NA T PFAM GGDEF domain containing protein HFDCGJPN_02041 1123400.KB904816_gene1558 2.6e-40 171.4 Gammaproteobacteria Bacteria 1N3I8@1224,1SYD7@1236,COG3755@1,COG3755@2 NA|NA|NA S Lysozyme inhibitor LprI HFDCGJPN_02046 265072.Mfla_2410 4.2e-35 154.8 Nitrosomonadales ltg Bacteria 1MZ4X@1224,2KMXE@206350,2VKFN@28216,COG0741@1,COG0741@2 NA|NA|NA M PFAM Lytic transglycosylase catalytic HFDCGJPN_02047 1165096.ARWF01000001_gene1943 8.7e-40 170.6 Nitrosomonadales Bacteria 1MZ5I@1224,2KN2E@206350,2VTYM@28216,COG2165@1,COG2165@2 NA|NA|NA NU Type II secretory pathway, pseudopilin HFDCGJPN_02048 1149133.ppKF707_1130 1.4e-36 159.1 Pseudomonas aeruginosa group oxpG ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1N1QJ@1224,1S8T4@1236,1YJSK@136841,COG2165@1,COG2165@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif HFDCGJPN_02049 1123368.AUIS01000016_gene2545 9.2e-46 189.9 Gammaproteobacteria ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1QVCD@1224,1T58B@1236,COG4968@1,COG4968@2 NA|NA|NA NU Prokaryotic N-terminal methylation motif HFDCGJPN_02050 582744.Msip34_1031 7.1e-153 547.7 Nitrosomonadales pulQ ko:K02453,ko:K07280,ko:K20444,ko:K20543 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000,ko02044 1.B.55.3,3.A.15,4.D.1.3 GT2,GT4 Bacteria 1QUY7@1224,2KKT1@206350,2VJ8Z@28216,COG3118@1,COG3118@2,COG4796@1,COG4796@2 NA|NA|NA U type II and III secretion system protein HFDCGJPN_02051 666681.M301_0465 1.3e-11 76.6 Betaproteobacteria Bacteria 1N89J@1224,2E5FR@1,2VVS4@28216,3307F@2 NA|NA|NA HFDCGJPN_02052 582744.Msip34_1029 2.3e-16 92.4 Nitrosomonadales pilO ko:K02664,ko:K02665 ko00000,ko02035,ko02044 Bacteria 1PIST@1224,2KNCJ@206350,2W61Q@28216,COG3167@1,COG3167@2 NA|NA|NA NU carbon utilization HFDCGJPN_02053 1434929.X946_3555 1.1e-64 253.4 Burkholderiaceae modE ko:K02019,ko:K05772 ko02010,map02010 M00186 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.6.2,3.A.1.6.4 Bacteria 1K2CT@119060,1P9SX@1224,2VMCH@28216,COG2005@1,COG2005@2,COG3585@1,COG3585@2 NA|NA|NA H Transcriptional regulator HFDCGJPN_02057 666681.M301_0552 0.0 1251.5 Nitrosomonadales 2.7.7.65 ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Bacteria 1MU2C@1224,2KKZP@206350,2VH3V@28216,COG2203@1,COG2203@2,COG5001@1,COG5001@2 NA|NA|NA T PFAM EAL domain protein HFDCGJPN_02058 666681.M301_0551 4.8e-145 521.2 Nitrosomonadales Bacteria 1N5T4@1224,2KMJ5@206350,2VK22@28216,COG2206@1,COG2206@2 NA|NA|NA T Domain of unknown function (DUF3391) HFDCGJPN_02059 1163617.SCD_n01384 2.6e-282 977.6 Betaproteobacteria recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1MVGG@1224,2VH8W@28216,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ HFDCGJPN_02060 1236959.BAMT01000002_gene2211 2.1e-26 125.6 Nitrosomonadales Bacteria 1MVUD@1224,2KKC7@206350,2VIYQ@28216,COG4409@1,COG4409@2 NA|NA|NA G exo-alpha-(2->6)-sialidase activity HFDCGJPN_02061 497321.C664_13127 4.6e-14 83.6 Rhodocyclales ko:K07727 ko00000,ko03000 Bacteria 1N9J3@1224,2KZ6K@206389,2VX89@28216,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain HFDCGJPN_02062 1123368.AUIS01000013_gene815 1.4e-74 286.6 Acidithiobacillales Bacteria 1R5Z9@1224,1T97C@1236,2NDZP@225057,COG4313@1,COG4313@2 NA|NA|NA C Protein involved in meta-pathway of phenol degradation HFDCGJPN_02064 314254.OA2633_07089 1.3e-19 102.4 Proteobacteria Bacteria 1P5B9@1224,28Z0K@1,2ZKT7@2 NA|NA|NA HFDCGJPN_02065 1236959.BAMT01000006_gene400 2.4e-164 585.5 Nitrosomonadales pilS 2.7.13.3 ko:K02668 ko02020,map02020 M00501 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 1QU7R@1224,2KM2K@206350,2VICU@28216,COG4191@1,COG4191@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain HFDCGJPN_02066 1165096.ARWF01000001_gene1307 3.4e-74 284.6 Nitrosomonadales sigE ko:K03088 ko00000,ko03021 Bacteria 1R9WC@1224,2KKU3@206350,2VQ28@28216,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family HFDCGJPN_02067 1236959.BAMT01000006_gene403 6.9e-17 93.6 Nitrosomonadales Bacteria 1NIWB@1224,2ESPS@1,2KNAU@206350,2W81E@28216,33K88@2 NA|NA|NA S Protein of unknown function (DUF3619) HFDCGJPN_02069 582744.Msip34_0236 1.2e-32 146.0 Nitrosomonadales VP2641 Bacteria 1REEC@1224,2KP96@206350,2VRE0@28216,COG1714@1,COG1714@2 NA|NA|NA S PFAM RDD domain containing protein HFDCGJPN_02070 582744.Msip34_0237 9.6e-152 543.1 Nitrosomonadales lptG ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 1MVW3@1224,2KM5V@206350,2VHA1@28216,COG0795@1,COG0795@2 NA|NA|NA S permease YjgP YjgQ family HFDCGJPN_02071 582744.Msip34_0238 2.3e-153 548.5 Nitrosomonadales lptF ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 1MUF2@1224,2KKPN@206350,2VH9C@28216,COG0795@1,COG0795@2 NA|NA|NA S permease YjgP YjgQ family HFDCGJPN_02072 582744.Msip34_0239 3.6e-221 774.2 Nitrosomonadales pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUF9@1224,2KKR5@206350,2VH79@28216,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides HFDCGJPN_02073 265072.Mfla_0223 1.2e-49 202.6 Nitrosomonadales holC GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MZ3V@1224,2KN6Q@206350,2VTYC@28216,COG2927@1,COG2927@2 NA|NA|NA L PFAM DNA polymerase III chi subunit HolC HFDCGJPN_02075 582744.Msip34_0242 9.3e-41 172.9 Nitrosomonadales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1RGV7@1224,2KMXJ@206350,2VSD7@28216,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein HFDCGJPN_02076 582744.Msip34_0243 2.2e-123 448.7 Nitrosomonadales pbpG GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258,ko:K07262 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1MWZA@1224,2KMAQ@206350,2VH1S@28216,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family HFDCGJPN_02077 582744.Msip34_0244 0.0 1422.9 Nitrosomonadales topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1MUFZ@1224,2KKIF@206350,2VHUF@28216,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone HFDCGJPN_02078 583345.Mmol_0290 3.6e-152 544.3 Nitrosomonadales ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 6.3.4.19 ko:K04075,ko:K14058 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1MW5Q@1224,2KM05@206350,2VHWH@28216,COG0037@1,COG0037@2 NA|NA|NA D Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system HFDCGJPN_02079 582744.Msip34_0246 1.2e-113 416.0 Nitrosomonadales Bacteria 1MUUV@1224,2KKSM@206350,2VK0U@28216,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM short-chain dehydrogenase reductase SDR HFDCGJPN_02080 582744.Msip34_0247 6.1e-128 464.2 Nitrosomonadales Bacteria 1N3CJ@1224,2KKBV@206350,2VHBE@28216,COG1565@1,COG1565@2 NA|NA|NA S Putative S-adenosyl-L-methionine-dependent methyltransferase HFDCGJPN_02081 265072.Mfla_0231 5.6e-100 370.5 Nitrosomonadales trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 1MUWJ@1224,2KM9A@206350,2VJN2@28216,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA HFDCGJPN_02082 582744.Msip34_0249 2.8e-91 341.7 Nitrosomonadales engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1MY3Z@1224,2KKZ0@206350,2VIKF@28216,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation HFDCGJPN_02083 582744.Msip34_0250 1.4e-83 315.8 Nitrosomonadales cyc Bacteria 1N2NB@1224,2KP5G@206350,2VQNZ@28216,COG2863@1,COG2863@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III HFDCGJPN_02084 582744.Msip34_0251 2.3e-252 878.2 Nitrosomonadales ccs1 ko:K07399 ko00000 Bacteria 1N6XE@1224,2KKXD@206350,2VJK9@28216,COG1333@1,COG1333@2 NA|NA|NA O ResB-like family HFDCGJPN_02085 582744.Msip34_0252 4e-180 637.5 Nitrosomonadales ccsA GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 Bacteria 1RG6M@1224,2KKDM@206350,2VI4N@28216,COG0755@1,COG0755@2 NA|NA|NA O TIGRFAM cytochrome c-type biogenesis protein CcsB HFDCGJPN_02086 265072.Mfla_0235 8.3e-130 470.3 Nitrosomonadales regB 2.7.13.3 ko:K07717,ko:K15011 ko02020,map02020 M00518,M00523 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1R49A@1224,2KMC6@206350,2VKU5@28216,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase-like ATPases HFDCGJPN_02087 265072.Mfla_0522 1.8e-106 392.1 Nitrosomonadales ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1MVIA@1224,2KKP4@206350,2VJ3W@28216,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components HFDCGJPN_02090 194439.CT1072 6e-51 207.2 Chlorobi tlpA Bacteria 1FE88@1090,COG0526@1,COG0526@2 NA|NA|NA CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HFDCGJPN_02091 319225.Plut_1571 1.3e-15 88.6 Chlorobi Bacteria 1FFJG@1090,2E3QA@1,32YN8@2 NA|NA|NA M Domain of unknown function (DUF4266) HFDCGJPN_02092 319225.Plut_1570 9.4e-102 377.1 Chlorobi Bacteria 1FE94@1090,COG2831@1,COG2831@2 NA|NA|NA U Protein of unknown function (DUF3570) HFDCGJPN_02093 1198452.Jab_1c05920 1.4e-100 372.9 Oxalobacteraceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1MW6K@1224,2VPGP@28216,472BX@75682,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein HFDCGJPN_02094 582744.Msip34_1243 1e-28 135.2 Betaproteobacteria Bacteria 1MU7T@1224,2VHFJ@28216,COG0823@1,COG0823@2,COG2931@1,COG2931@2 NA|NA|NA Q PFAM Hemolysin-type calcium-binding HFDCGJPN_02095 1101195.Meth11DRAFT_0048 1.7e-185 656.0 Nitrosomonadales dsbD GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009266,GO:0009628,GO:0009898,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042221,GO:0042493,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071502,GO:0071840,GO:0071944,GO:0098552,GO:0098562,GO:0140096 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 iECSE_1348.ECSE_4435 Bacteria 1MU8W@1224,2KKIB@206350,2VI8I@28216,COG4232@1,COG4232@2 NA|NA|NA CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps HFDCGJPN_02096 1502770.JQMG01000001_gene1303 1.4e-136 492.7 Nitrosomonadales qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1MU4N@1224,2KKR9@206350,2VIU4@28216,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase HFDCGJPN_02097 1132855.KB913035_gene159 1.1e-161 576.2 Nitrosomonadales yqhD ko:K00100,ko:K08325,ko:K19955 ko00640,ko00650,ko01120,map00640,map00650,map01120 R02528,R03544,R03545 RC00087,RC00739 ko00000,ko00001,ko01000 Bacteria 1QUBJ@1224,2KNU8@206350,2VHQE@28216,COG1979@1,COG1979@2 NA|NA|NA C Iron-containing alcohol dehydrogenase HFDCGJPN_02098 1132855.KB913035_gene158 3.6e-71 274.6 Betaproteobacteria ko:K16137 ko00000,ko03000 Bacteria 1RA4T@1224,2VQJU@28216,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator HFDCGJPN_02099 1000565.METUNv1_03477 1.2e-37 162.5 Rhodocyclales Bacteria 1MZ7P@1224,2DM6D@1,2KYYM@206389,2VUHB@28216,31WQ8@2 NA|NA|NA HFDCGJPN_02100 1236959.BAMT01000001_gene1689 6e-152 544.3 Nitrosomonadales amiC GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225 Bacteria 1MUQK@1224,2KKBH@206350,2VHXN@28216,COG0860@1,COG0860@2 NA|NA|NA M Ami_3 HFDCGJPN_02101 582744.Msip34_1284 2e-58 231.9 Nitrosomonadales yjeE GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102,ko:K07452 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko02048,ko03016 Bacteria 1RGYU@1224,2KMRX@206350,2VSJY@28216,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE HFDCGJPN_02102 1236959.BAMT01000001_gene1687 2.2e-164 585.1 Nitrosomonadales queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1MV1H@1224,2KM7D@206350,2VI7V@28216,COG1600@1,COG1600@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) HFDCGJPN_02103 265072.Mfla_1378 1.3e-168 599.7 Nitrosomonadales Bacteria 1NSSV@1224,2KPA3@206350,2WH9S@28216,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase HFDCGJPN_02104 582744.Msip34_1281 6.9e-141 506.9 Nitrosomonadales yfdH 2.4.1.83 ko:K00721,ko:K20534 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1QTWU@1224,2KKY5@206350,2WGWG@28216,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 HFDCGJPN_02105 1101195.Meth11DRAFT_1647 6.9e-39 166.8 Nitrosomonadales Bacteria 1N6WN@1224,2KN76@206350,2VW0C@28216,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein HFDCGJPN_02106 1101195.Meth11DRAFT_1646 5.6e-72 277.7 Nitrosomonadales 3.5.1.105 ko:K03478 ko00000,ko01000 Bacteria 1MX3P@1224,2KMMB@206350,2VSK0@28216,COG3394@1,COG3394@2 NA|NA|NA G YdjC-like protein HFDCGJPN_02107 582744.Msip34_1279 1.6e-47 195.7 Nitrosomonadales Bacteria 1PJHE@1224,2BZ0G@1,2KN1S@206350,2W7ZX@28216,30XN9@2 NA|NA|NA HFDCGJPN_02108 1165096.ARWF01000001_gene694 5.4e-151 541.2 Nitrosomonadales ndvC 3.2.1.58 ko:K01210,ko:K03292 ko00500,map00500 R00308,R03115 RC00467 ko00000,ko00001,ko01000 2.A.2 Bacteria 1MWJJ@1224,2KKP0@206350,2VIIU@28216,COG5309@1,COG5309@2 NA|NA|NA G beta (1-6) glucans synthase HFDCGJPN_02109 1101195.Meth11DRAFT_1643 0.0 1376.3 Nitrosomonadales ndvB 2.4.1.12,3.2.1.58 ko:K00694,ko:K01210,ko:K03292 ko00500,ko01100,ko02026,map00500,map01100,map02026 R00308,R02889,R03115 RC00005,RC00467 ko00000,ko00001,ko01000,ko01003,ko02000 2.A.2,4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 1MWF8@1224,2KM1U@206350,2VHGG@28216,COG1215@1,COG1215@2,COG5309@1,COG5309@2 NA|NA|NA M Glycosyl transferase family 21 HFDCGJPN_02110 582744.Msip34_1275 5.2e-230 803.9 Nitrosomonadales yjcC 3.1.4.52 ko:K20963 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1MVJY@1224,2KKRP@206350,2VI53@28216,COG0517@1,COG0517@2,COG2199@1,COG2199@2,COG2200@1,COG2200@2 NA|NA|NA T PFAM EAL domain HFDCGJPN_02112 1165096.ARWF01000001_gene2365 1.4e-72 279.3 Nitrosomonadales frlR ko:K03710 ko00000,ko03000 Bacteria 1MUEB@1224,2KM9E@206350,2VJ6N@28216,COG2188@1,COG2188@2 NA|NA|NA K PFAM UbiC transcription regulator-associated domain protein HFDCGJPN_02113 666681.M301_0693 2.3e-178 631.7 Nitrosomonadales maeB 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU0A@1224,2KMFE@206350,2VIYB@28216,COG0281@1,COG0281@2 NA|NA|NA C PFAM malic protein NAD-binding HFDCGJPN_02114 1101195.Meth11DRAFT_1844 2.4e-26 125.2 Nitrosomonadales sdhC GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0008177,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0017004,GO:0020037,GO:0022607,GO:0022900,GO:0034622,GO:0043933,GO:0044085,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0048038,GO:0048039,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0097159,GO:1901363 ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 iSF_1195.SF0576,iS_1188.S0589 Bacteria 1RIGZ@1224,2KN5Q@206350,2VWRY@28216,COG2009@1,COG2009@2 NA|NA|NA C TIGRFAM succinate dehydrogenase, cytochrome b556 subunit HFDCGJPN_02115 323848.Nmul_A0862 5.7e-21 107.1 Nitrosomonadales sdhD GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 e_coli_core.b0722,iAF1260.b0722,iAPECO1_1312.APECO1_1356,iB21_1397.B21_00671,iBWG_1329.BWG_0581,iE2348C_1286.E2348C_0602,iEC042_1314.EC042_0740,iECABU_c1320.ECABU_c07680,iECBD_1354.ECBD_2938,iECB_1328.ECB_00682,iECDH10B_1368.ECDH10B_0789,iECDH1ME8569_1439.ECDH1ME8569_0681,iECD_1391.ECD_00682,iECED1_1282.ECED1_0692,iECIAI1_1343.ECIAI1_0696,iECIAI39_1322.ECIAI39_0680,iECNA114_1301.ECNA114_0658,iECO103_1326.ECO103_0716,iECO111_1330.ECO111_0739,iECO26_1355.ECO26_0783,iECOK1_1307.ECOK1_0722,iECP_1309.ECP_0734,iECS88_1305.ECS88_0748,iECSE_1348.ECSE_0782,iECSF_1327.ECSF_0655,iECUMN_1333.ECUMN_0800,iECW_1372.ECW_m0777,iEKO11_1354.EKO11_3157,iETEC_1333.ETEC_0733,iEcDH1_1363.EcDH1_2913,iEcE24377_1341.EcE24377A_0749,iEcHS_1320.EcHS_A0770,iEcSMS35_1347.EcSMS35_0735,iEcolC_1368.EcolC_2933,iJO1366.b0722,iJR904.b0722,iLF82_1304.LF82_2100,iNRG857_1313.NRG857_03215,iSBO_1134.SBO_0580,iSDY_1059.SDY_0660,iSFV_1184.SFV_0613,iSF_1195.SF0575,iSFxv_1172.SFxv_0634,iSSON_1240.SSON_0673,iS_1188.S0588,iUMN146_1321.UM146_14010,iUMNK88_1353.UMNK88_758,iUTI89_1310.UTI89_C0718,iWFL_1372.ECW_m0777,iY75_1357.Y75_RS03755,ic_1306.c0800 Bacteria 1MZR9@1224,2VSJN@28216,373DV@32003,COG2142@1,COG2142@2 NA|NA|NA C Succinate dehydrogenase/Fumarate reductase transmembrane subunit HFDCGJPN_02116 582744.Msip34_1844 3.6e-20 104.0 Nitrosomonadales trmJ GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.200,3.5.1.19,6.1.1.16 ko:K01883,ko:K02533,ko:K08281,ko:K15396 ko00760,ko00970,ko01100,map00760,map00970,map01100 M00359,M00360 R01268,R03650 RC00055,RC00100,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1N47Y@1224,2KM4J@206350,2VI2D@28216,COG0565@1,COG0565@2 NA|NA|NA J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA HFDCGJPN_02117 582744.Msip34_1845 2.3e-120 438.3 Nitrosomonadales cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0840 Bacteria 1MVFX@1224,2KKVB@206350,2VH8C@28216,COG1045@1,COG1045@2 NA|NA|NA E TIGRFAM serine O-acetyltransferase HFDCGJPN_02118 1132855.KB913035_gene973 3.7e-60 237.7 Nitrosomonadales iscR 2.8.1.7 ko:K04487,ko:K13643 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03000,ko03016,ko03029 Bacteria 1RDA4@1224,2KMV0@206350,2VRGK@28216,COG1959@1,COG1959@2 NA|NA|NA K TIGRFAM transcriptional regulator, Rrf2 family HFDCGJPN_02119 1236959.BAMT01000001_gene1093 1.1e-140 506.5 Nitrosomonadales 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1MU1C@1224,2KKUC@206350,2VH91@28216,COG1104@1,COG1104@2 NA|NA|NA E Beta-eliminating lyase HFDCGJPN_02120 582744.Msip34_1848 7.9e-219 766.1 Nitrosomonadales iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 iPC815.YPO2896,iYL1228.KPN_02862 Bacteria 1MU1C@1224,2KM7T@206350,2VH91@28216,COG1104@1,COG1104@2 NA|NA|NA E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins HFDCGJPN_02121 1101195.Meth11DRAFT_1877 2.6e-62 244.6 Nitrosomonadales iscU ko:K04488 ko00000 Bacteria 1RD5K@1224,2KMMJ@206350,2VQ2I@28216,COG0822@1,COG0822@2 NA|NA|NA C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters HFDCGJPN_02122 1132855.KB913035_gene969 3.1e-53 214.2 Nitrosomonadales iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 ko:K13628 ko00000,ko03016 iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053 Bacteria 1RH6T@1224,2KMUB@206350,2VSKY@28216,COG0316@1,COG0316@2 NA|NA|NA S TIGRFAM iron-sulfur cluster assembly protein IscA HFDCGJPN_02123 59538.XP_005974535.1 9.7e-49 199.9 Metazoa GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 ko:K04082,ko:K15151 ko00000,ko03021,ko03029,ko03110 Metazoa 3A0FM@33154,3BM4M@33208,COG1076@1,KOG3192@2759 NA|NA|NA O iron-sulfur cluster co-chaperone HFDCGJPN_02124 582744.Msip34_1852 2.8e-284 984.2 Nitrosomonadales hscA GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010467,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051604,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0097428,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1903506,GO:1990230,GO:1990234,GO:2001141 ko:K04043,ko:K04044 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33,1.A.33.1 Bacteria 1MVQI@1224,2KKJA@206350,2VHGV@28216,COG0443@1,COG0443@2 NA|NA|NA O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB HFDCGJPN_02125 582744.Msip34_1853 3.8e-54 217.2 Nitrosomonadales fdx ko:K04755 ko00000 Bacteria 1RHDC@1224,2KMYK@206350,2VSQE@28216,COG0633@1,COG0633@2 NA|NA|NA C TIGRFAM ferredoxin, 2Fe-2S type, ISC system HFDCGJPN_02126 1236959.BAMT01000006_gene393 4.9e-85 322.0 Nitrosomonadales ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 1R6AZ@1224,2KMJX@206350,2VYMB@28216,COG3746@1,COG3746@2 NA|NA|NA P PFAM phosphate-selective porin O and P HFDCGJPN_02127 582744.Msip34_1857 1.8e-249 868.2 Nitrosomonadales lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 1MX1V@1224,2KMH7@206350,2VH1A@28216,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family HFDCGJPN_02128 1132855.KB913035_gene954 1.5e-150 538.9 Nitrosomonadales prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1MUAW@1224,2KMIT@206350,2VJ6C@28216,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA HFDCGJPN_02129 1101195.Meth11DRAFT_1895 2.1e-153 548.5 Nitrosomonadales pstS GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0016020,GO:0042301,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051234,GO:0071944 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MUH9@1224,2KMCK@206350,2VKAU@28216,COG0226@1,COG0226@2 NA|NA|NA P TIGRFAM phosphate binding protein HFDCGJPN_02130 582744.Msip34_1860 1.2e-142 512.7 Nitrosomonadales pstC ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MVKP@1224,2KKVV@206350,2VH4G@28216,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane HFDCGJPN_02131 582744.Msip34_1861 2.3e-149 535.0 Nitrosomonadales pstA ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1MUWB@1224,2KKYY@206350,2VH6Y@28216,COG0581@1,COG0581@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component HFDCGJPN_02132 1165096.ARWF01000001_gene815 5.9e-135 486.9 Nitrosomonadales pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 1MU16@1224,2KKPQ@206350,2VI4J@28216,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system HFDCGJPN_02133 1163617.SCD_n02805 6.4e-213 746.9 Betaproteobacteria 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1MXI2@1224,2VKXB@28216,COG1785@1,COG1785@2 NA|NA|NA P Belongs to the alkaline phosphatase family HFDCGJPN_02134 1163617.SCD_n02806 3.5e-54 218.4 Betaproteobacteria Bacteria 1ND0P@1224,2E94M@1,2VWRM@28216,333DG@2 NA|NA|NA HFDCGJPN_02135 1395571.TMS3_0118290 1.2e-35 156.8 Gammaproteobacteria xcmX Bacteria 1MZ5I@1224,1SBEY@1236,COG2165@1,COG2165@2 NA|NA|NA NU Type II secretory pathway pseudopilin HFDCGJPN_02136 1123368.AUIS01000016_gene2544 8.7e-31 139.8 Gammaproteobacteria oxpG ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1N1QJ@1224,1S8T4@1236,COG2165@1,COG2165@2 NA|NA|NA U Type II secretion system protein G HFDCGJPN_02137 1123393.KB891329_gene1064 1.5e-43 182.6 Hydrogenophilales ko:K02456 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1KSIT@119069,1QVCD@1224,2WGQ3@28216,COG4968@1,COG4968@2 NA|NA|NA NU Pfam:N_methyl_2 HFDCGJPN_02138 1095769.CAHF01000022_gene428 1.4e-121 443.7 Oxalobacteraceae pulQ ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1QUY7@1224,2VJ8Z@28216,472RY@75682,COG4796@1,COG4796@2 NA|NA|NA U Secretin and TonB N terminus short domain HFDCGJPN_02139 883126.HMPREF9710_03910 1e-10 73.6 Oxalobacteraceae Bacteria 1N89J@1224,2E5FR@1,2VVS4@28216,3307F@2,477AQ@75682 NA|NA|NA HFDCGJPN_02140 666681.M301_0729 2.2e-11 75.9 Nitrosomonadales pilO ko:K02664,ko:K02665,ko:K12280 ko00000,ko02035,ko02044 Bacteria 1PIST@1224,2KNCJ@206350,2W61Q@28216,COG3167@1,COG3167@2 NA|NA|NA NU carbon utilization HFDCGJPN_02141 1131553.JIBI01000005_gene2180 7.2e-07 60.8 Nitrosomonadales Bacteria 1NA23@1224,2E3Q5@1,2VVXW@28216,32YN4@2,3736Z@32003 NA|NA|NA HFDCGJPN_02144 265072.Mfla_0633 1.2e-202 712.6 Nitrosomonadales ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1MVFY@1224,2KM2J@206350,2VHRH@28216,COG0348@1,COG0348@2 NA|NA|NA C TIGRFAM cytochrome c oxidase accessory protein HFDCGJPN_02145 582744.Msip34_2139 8.7e-149 533.1 Nitrosomonadales ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 1MUCW@1224,2KMD1@206350,2VHGS@28216,COG2010@1,COG2010@2 NA|NA|NA C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex HFDCGJPN_02146 1236959.BAMT01000004_gene800 7.4e-17 92.4 Nitrosomonadales Bacteria 1NJW1@1224,2EHQ5@1,2KP0N@206350,2VXSI@28216,33BFX@2 NA|NA|NA S Cbb3-type cytochrome oxidase component FixQ HFDCGJPN_02147 582744.Msip34_2141 3.1e-125 454.5 Nitrosomonadales ccoO 1.9.3.1 ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0145 Bacteria 1MXEY@1224,2KMM8@206350,2VIJ2@28216,COG2993@1,COG2993@2 NA|NA|NA C PFAM cytochrome C oxidase mono-heme subunit FixO HFDCGJPN_02148 582744.Msip34_2142 5.8e-261 906.4 Nitrosomonadales ccoN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K00404,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144 Bacteria 1MU18@1224,2KKTV@206350,2VIWB@28216,COG3278@1,COG3278@2 NA|NA|NA C TIGRFAM cytochrome c oxidase, cbb3-type, subunit I HFDCGJPN_02149 1132855.KB913035_gene766 2.2e-61 241.9 Nitrosomonadales hyaE GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 ko:K03619,ko:K07152 ko00000,ko03029 Bacteria 1RHJ8@1224,2KMU7@206350,2VR3M@28216,COG1999@1,COG1999@2 NA|NA|NA S PFAM electron transport protein SCO1 SenC HFDCGJPN_02150 666681.M301_1623 7.5e-108 396.7 Nitrosomonadales purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 iSDY_1059.SDY_1135 Bacteria 1N3KA@1224,2KKHD@206350,2VH4M@28216,COG0027@1,COG0027@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate HFDCGJPN_02151 582744.Msip34_1740 9.2e-61 239.6 Nitrosomonadales yjbI ko:K06886 ko00000 Bacteria 1RH21@1224,2KMSJ@206350,2VSUJ@28216,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin HFDCGJPN_02152 1236959.BAMT01000009_gene3414 1.8e-176 625.5 Nitrosomonadales rhlE2 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1MU49@1224,2KM0R@206350,2VH16@28216,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family HFDCGJPN_02153 582744.Msip34_1738 5.5e-154 550.8 Nitrosomonadales srmB GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008104,GO:0008143,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0033036,GO:0033592,GO:0034622,GO:0034641,GO:0035770,GO:0036464,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0046483,GO:0051179,GO:0060293,GO:0065003,GO:0070035,GO:0070717,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901363,GO:1990904 3.6.4.13 ko:K05590,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1MU49@1224,2KM5U@206350,2VH16@28216,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family HFDCGJPN_02155 1150469.RSPPHO_02405 7.7e-169 600.1 Rhodospirillales dctA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 2.A.23.1.3,2.A.23.1.6,2.A.23.1.7 Bacteria 1MU0Q@1224,2JPKH@204441,2TRET@28211,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family HFDCGJPN_02156 582744.Msip34_1757 5.3e-95 354.0 Nitrosomonadales Bacteria 1RA5I@1224,2C8XG@1,2KKNU@206350,2VQGY@28216,2Z7PK@2 NA|NA|NA S Protein of unknown function (DUF4197) HFDCGJPN_02157 582744.Msip34_1758 0.0 1417.5 Nitrosomonadales glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 1MW4J@1224,2KKJ1@206350,2VJIJ@28216,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties HFDCGJPN_02158 582744.Msip34_0855 1.1e-86 326.2 Nitrosomonadales fucA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008270,GO:0008738,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046372,GO:0046872,GO:0046914,GO:0071704,GO:1901575 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 R02262 RC00603,RC00604 ko00000,ko00001,ko01000 Bacteria 1MW7B@1224,2KM3S@206350,2VQBC@28216,COG0235@1,COG0235@2 NA|NA|NA G PFAM class II aldolase adducin family protein HFDCGJPN_02159 1502770.JQMG01000001_gene1641 2.5e-136 491.9 Nitrosomonadales mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUPM@1224,2KKV9@206350,2VI2X@28216,COG0182@1,COG0182@2 NA|NA|NA J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) HFDCGJPN_02160 1101195.Meth11DRAFT_1667 6.1e-90 337.4 Nitrosomonadales yjjV ko:K03424 ko00000,ko01000 Bacteria 1MW5C@1224,2KKFJ@206350,2VH67@28216,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase HFDCGJPN_02161 582744.Msip34_0834 3.9e-132 478.0 Nitrosomonadales ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 Bacteria 1MUWT@1224,2KM29@206350,2VI9P@28216,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate HFDCGJPN_02162 666681.M301_1078 1.7e-32 145.6 Nitrosomonadales Bacteria 1P4TY@1224,28WCY@1,2KN05@206350,2W7ZQ@28216,2ZID9@2 NA|NA|NA HFDCGJPN_02163 1165096.ARWF01000001_gene689 4.4e-74 283.9 Nitrosomonadales nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1RE7V@1224,2KMPK@206350,2VR9P@28216,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes HFDCGJPN_02164 582744.Msip34_0832 2.1e-227 794.7 Nitrosomonadales glyA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 iIT341.HP0183 Bacteria 1MUIS@1224,2KKD4@206350,2VJ4F@28216,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism HFDCGJPN_02165 1165096.ARWF01000001_gene691 2e-23 114.4 Nitrosomonadales iscX GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 Bacteria 1N7C1@1224,2KN9E@206350,2VVQU@28216,COG2975@1,COG2975@2 NA|NA|NA S Iron-sulphur cluster assembly HFDCGJPN_02166 1198452.Jab_2c31010 3.4e-92 345.1 Oxalobacteraceae yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 ko:K07019 ko00000 Bacteria 1MWV1@1224,2VHZ1@28216,473G7@75682,COG0429@1,COG0429@2 NA|NA|NA S alpha/beta hydrolase fold HFDCGJPN_02167 265072.Mfla_1921 1.4e-216 758.8 Nitrosomonadales algC GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUA5@1224,2KKKG@206350,2VJ29@28216,COG1109@1,COG1109@2 NA|NA|NA G phosphoglucomutase phosphomannomutase alpha beta alpha domain I HFDCGJPN_02168 1123368.AUIS01000015_gene2619 4.3e-42 178.3 Gammaproteobacteria ynaJ Bacteria 1QVX4@1224,1T2MJ@1236,COG3182@1,COG3182@2 NA|NA|NA S PepSY-associated TM region HFDCGJPN_02169 1123368.AUIS01000015_gene2618 1.5e-39 169.5 Gammaproteobacteria rnfG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03612 ko00000 Bacteria 1MZVX@1224,1S9KJ@1236,COG4659@1,COG4659@2 NA|NA|NA C FMN-binding HFDCGJPN_02170 1123368.AUIS01000015_gene2615 1.4e-93 350.1 Gammaproteobacteria ko:K12065 ko00000,ko02044 3.A.7.11.1 Bacteria 1QW3W@1224,1T2RV@1236,COG2433@1,COG2433@2 NA|NA|NA S Pfam Transposase IS66 HFDCGJPN_02171 1101195.Meth11DRAFT_1675 2e-47 195.7 Nitrosomonadales orf ko:K06985 ko04112,map04112 ko00000,ko00001 Bacteria 1N2PE@1224,2KMXG@206350,2VTH4@28216,COG3577@1,COG3577@2 NA|NA|NA S gag-polyprotein putative aspartyl protease HFDCGJPN_02172 582744.Msip34_0822 7.8e-262 909.4 Nitrosomonadales pgm 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU5S@1224,2KKHB@206350,2VKCX@28216,COG0033@1,COG0033@2 NA|NA|NA G phosphoglucomutase phosphomannomutase alpha beta alpha domain I HFDCGJPN_02174 1430440.MGMSRv2_1899 8e-32 142.9 Alphaproteobacteria Bacteria 1N8VK@1224,2E7QP@1,2UG0V@28211,33262@2 NA|NA|NA HFDCGJPN_02177 265072.Mfla_0065 3.3e-58 231.1 Nitrosomonadales rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1RDP2@1224,2KMM1@206350,2VSRT@28216,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits HFDCGJPN_02178 582744.Msip34_0069 4.3e-235 820.5 Nitrosomonadales nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 1MWT7@1224,2KKJJ@206350,2VH2X@28216,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination HFDCGJPN_02179 582744.Msip34_0070 0.0 1320.8 Nitrosomonadales infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1MV26@1224,2KKNG@206350,2VK2H@28216,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex HFDCGJPN_02180 582744.Msip34_0071 8.8e-49 199.5 Nitrosomonadales rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1MZPE@1224,2KMXN@206350,2VR43@28216,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA HFDCGJPN_02181 582744.Msip34_2160 5.2e-166 590.5 Nitrosomonadales cysA GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 3.6.3.25,3.6.3.29 ko:K02017,ko:K02045,ko:K10112 ko00920,ko02010,map00920,map02010 M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.6.1,3.A.1.6.3,3.A.1.8 Bacteria 1QTTT@1224,2KKT8@206350,2VH92@28216,COG1118@1,COG1118@2 NA|NA|NA P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system HFDCGJPN_02182 582744.Msip34_2159 4.7e-136 490.7 Nitrosomonadales cysW ko:K02047 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 Bacteria 1MV8X@1224,2KM7E@206350,2VI3S@28216,COG4208@1,COG4208@2 NA|NA|NA P TIGRFAM sulfate ABC transporter, inner membrane subunit CysW HFDCGJPN_02183 582744.Msip34_2158 1.9e-131 475.3 Nitrosomonadales cysT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02018,ko:K02046 ko00920,ko02010,map00920,map02010 M00185,M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3,3.A.1.8 iJN746.PP_5170 Bacteria 1QTTU@1224,2KMAW@206350,2VHKY@28216,COG0555@1,COG0555@2 NA|NA|NA O TIGRFAM sulfate ABC transporter, inner membrane subunit CysT HFDCGJPN_02184 666681.M301_0109 1.6e-117 429.1 Nitrosomonadales Bacteria 1RM23@1224,2KKU9@206350,2VSFS@28216,COG2200@1,COG2200@2 NA|NA|NA T PFAM EAL domain HFDCGJPN_02185 582744.Msip34_2156 7e-157 560.1 Nitrosomonadales sbp ko:K02048 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 Bacteria 1MUAU@1224,2KMFK@206350,2VIQZ@28216,COG1613@1,COG1613@2 NA|NA|NA P TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein HFDCGJPN_02186 522306.CAP2UW1_3938 4.8e-106 391.3 unclassified Betaproteobacteria chaA ko:K07300 ko00000,ko02000 2.A.19 iNJ661.Rv1607 Bacteria 1KQGX@119066,1MWD8@1224,2VJQM@28216,COG0387@1,COG0387@2 NA|NA|NA P Sodium/calcium exchanger protein HFDCGJPN_02187 265072.Mfla_0615 8.4e-126 456.8 Nitrosomonadales srpH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVFX@1224,2KM8X@206350,2VHZF@28216,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) HFDCGJPN_02188 1502770.JQMG01000001_gene546 5.7e-161 573.5 Nitrosomonadales srpI 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1MW6M@1224,2KKR8@206350,2VHR8@28216,COG0664@1,COG0664@2 NA|NA|NA T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein HFDCGJPN_02189 582744.Msip34_1420 3.8e-69 267.7 Nitrosomonadales hpnD 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1MX4W@1224,2KKYA@206350,2VJ13@28216,COG1562@1,COG1562@2 NA|NA|NA I TIGRFAM squalene synthase HpnD HFDCGJPN_02190 1236959.BAMT01000001_gene1547 7.7e-119 434.1 Nitrosomonadales hpnE 1.17.8.1 ko:K21677 ko00000,ko01000 Bacteria 1NQUH@1224,2KM1H@206350,2VJV1@28216,COG1232@1,COG1232@2 NA|NA|NA H TIGRFAM squalene-associated FAD-dependent desaturase HFDCGJPN_02191 582744.Msip34_1422 7.6e-38 163.3 Nitrosomonadales yvlD ko:K08972 ko00000 Bacteria 1N1DF@1224,2KNWB@206350,2VUY1@28216,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV HFDCGJPN_02192 582744.Msip34_1423 5.6e-103 380.6 Betaproteobacteria Bacteria 1MWBC@1224,2VMWZ@28216,COG1028@1,COG1028@2 NA|NA|NA IQ dehydrogenase reductase HFDCGJPN_02193 582744.Msip34_1424 8.5e-32 142.5 Nitrosomonadales Bacteria 1PJUQ@1224,2A8WH@1,2KP2A@206350,2W86J@28216,30XZW@2 NA|NA|NA HFDCGJPN_02195 1101195.Meth11DRAFT_1780 4.3e-122 444.5 Nitrosomonadales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524,ko:K04096 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1MWCC@1224,2KMHI@206350,2VNXD@28216,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor HFDCGJPN_02196 1236959.BAMT01000010_gene3235 8.6e-46 190.7 Nitrosomonadales coaX 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUYA@1224,2KN1X@206350,2VK1G@28216,COG1521@1,COG1521@2 NA|NA|NA K Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis HFDCGJPN_02197 388413.ALPR1_10680 8.5e-15 87.4 Bacteria oprH ko:K02014,ko:K16087,ko:K20276 ko02024,map02024 ko00000,ko00001,ko02000 1.B.14,1.B.14.2 Bacteria COG2373@1,COG2373@2,COG2911@1,COG2911@2,COG2982@1,COG2982@2,COG3210@1,COG3210@2,COG3637@1,COG3637@2,COG3897@1,COG3897@2,COG4932@1,COG4932@2 NA|NA|NA P peptidase activity, acting on L-amino acid peptides HFDCGJPN_02198 1101195.Meth11DRAFT_2193 6.3e-160 570.1 Nitrosomonadales ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1MVB0@1224,2KKQW@206350,2VHR7@28216,COG0115@1,COG0115@2 NA|NA|NA E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family HFDCGJPN_02199 1502770.JQMG01000001_gene1367 3.2e-26 123.6 Nitrosomonadales MA20_32275 Bacteria 1N7QM@1224,2KNBC@206350,2VVV6@28216,COG4391@1,COG4391@2 NA|NA|NA S Zinc-finger domain HFDCGJPN_02200 1236959.BAMT01000004_gene792 1.7e-89 335.9 Nitrosomonadales murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1NAI2@1224,2KM95@206350,2VQ46@28216,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis HFDCGJPN_02202 582744.Msip34_2147 2.8e-70 271.6 Nitrosomonadales yvqK 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1RDUF@1224,2KMKJ@206350,2VQ7P@28216,COG2096@1,COG2096@2 NA|NA|NA S PFAM Cobalamin adenosyltransferase HFDCGJPN_02203 582744.Msip34_2148 1.3e-11 75.1 Nitrosomonadales IV02_21350 Bacteria 1PJKQ@1224,2KNCF@206350,2W81S@28216,COG5583@1,COG5583@2 NA|NA|NA S Uncharacterized small protein (DUF2292) HFDCGJPN_02204 582744.Msip34_2149 9e-185 653.3 Nitrosomonadales ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 1R9AP@1224,2KNN1@206350,2W0HU@28216,COG3746@1,COG3746@2 NA|NA|NA P PFAM phosphate-selective porin O and P HFDCGJPN_02205 224911.27351823 4.6e-26 126.7 Bradyrhizobiaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1MU7T@1224,2TRVY@28211,3JUXC@41294,COG0823@1,COG0823@2,COG2911@1,COG2911@2,COG2931@1,COG2931@2,COG3209@1,COG3209@2 NA|NA|NA MQ COG2931 RTX toxins and related Ca2 -binding proteins HFDCGJPN_02206 211586.SO_2199 2.5e-11 76.3 Shewanellaceae Bacteria 1N7AR@1224,1SG7N@1236,2QEHD@267890,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety HFDCGJPN_02207 583345.Mmol_0780 2.5e-51 208.8 Nitrosomonadales ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 1N8MU@1224,2KMXU@206350,2VV2P@28216,COG2197@1,COG2197@2 NA|NA|NA K PFAM regulatory protein LuxR HFDCGJPN_02208 666681.M301_0714 2.4e-179 635.2 Nitrosomonadales lapC ko:K02022,ko:K12542 M00330 ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 Bacteria 1MUI8@1224,2KKH6@206350,2VIAA@28216,COG0845@1,COG0845@2 NA|NA|NA M TIGRFAM type I secretion membrane fusion protein, HlyD family HFDCGJPN_02209 582744.Msip34_1008 5.5e-300 1036.6 Nitrosomonadales lapB ko:K12541 ko02010,map02010 M00330 ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 Bacteria 1R2T0@1224,2KMDW@206350,2VP2B@28216,COG2274@1,COG2274@2 NA|NA|NA V TIGRFAM type I secretion system ATPase HFDCGJPN_02213 1502770.JQMG01000001_gene2386 6.3e-131 474.6 Nitrosomonadales Bacteria 1MV8P@1224,2KMD5@206350,2VNJT@28216,COG3746@1,COG3746@2 NA|NA|NA P Putative porin HFDCGJPN_02214 1502770.JQMG01000001_gene2387 6e-54 217.6 Nitrosomonadales tonB2 ko:K03832,ko:K07277 ko00000,ko02000,ko03029 1.B.33,2.C.1.1 Bacteria 1RFY5@1224,2KM40@206350,2VR5E@28216,COG0810@1,COG0810@2 NA|NA|NA M TonB C terminal HFDCGJPN_02215 265072.Mfla_2402 4.4e-57 227.3 Nitrosomonadales exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 1RF1B@1224,2KMNC@206350,2VRZF@28216,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR HFDCGJPN_02216 265072.Mfla_2403 6.2e-51 206.8 Nitrosomonadales exbD2 ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 1RJCA@1224,2KP85@206350,2VSW4@28216,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR HFDCGJPN_02217 1288494.EBAPG3_5000 1.1e-186 659.8 Nitrosomonadales exbB ko:K03561,ko:K03562 ko01120,map01120 ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 Bacteria 1N2RJ@1224,2VM7W@28216,372QU@32003,COG0811@1,COG0811@2 NA|NA|NA U Domain of unknown function (DUF2341) HFDCGJPN_02218 1502770.JQMG01000001_gene2391 2.8e-166 592.0 Nitrosomonadales fhaC5 Bacteria 1PRBP@1224,2KMHZ@206350,2VHDS@28216,COG2831@1,COG2831@2 NA|NA|NA U Haemolysin secretion/activation protein ShlB/FhaC/HecB HFDCGJPN_02219 1502770.JQMG01000001_gene2392 1.1e-92 347.1 Nitrosomonadales Bacteria 1MXIP@1224,2KPAB@206350,2VHH4@28216,COG3210@1,COG3210@2 NA|NA|NA U COG3210 Large exoproteins involved in heme utilization or adhesion HFDCGJPN_02220 583345.Mmol_0207 3.6e-140 505.4 Nitrosomonadales ko:K07221 ko00000,ko02000 1.B.5.1 Bacteria 1R9AP@1224,2KNN1@206350,2W0HU@28216,COG3746@1,COG3746@2 NA|NA|NA P PFAM phosphate-selective porin O and P HFDCGJPN_02221 583345.Mmol_0206 1.1e-162 579.3 Nitrosomonadales sbp ko:K02048 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 Bacteria 1MUAU@1224,2KKVC@206350,2VIQZ@28216,COG1613@1,COG1613@2 NA|NA|NA P TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein HFDCGJPN_02222 1165096.ARWF01000001_gene1631 1.1e-171 609.4 Nitrosomonadales hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUG1@1224,2KM65@206350,2VHC2@28216,COG0407@1,COG0407@2 NA|NA|NA H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III HFDCGJPN_02223 582744.Msip34_2804 5.9e-158 563.5 Nitrosomonadales gltD 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iSB619.SA_RS02450 Bacteria 1MU2H@1224,2KKRV@206350,2VIHR@28216,COG0493@1,COG0493@2 NA|NA|NA E TIGRFAM glutamate synthase, NADH NADPH, small subunit HFDCGJPN_02224 666681.M301_1238 3.5e-86 325.1 Nitrosomonadales rgpB ko:K12991,ko:K12997 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1R132@1224,2KNDT@206350,2VT3B@28216,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 HFDCGJPN_02225 886882.PPSC2_c4822 2e-49 203.0 Paenibacillaceae rgpB ko:K12991,ko:K12997 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1V49N@1239,26WEX@186822,4ISDQ@91061,COG1216@1,COG1216@2 NA|NA|NA S involved in cell wall biogenesis HFDCGJPN_02226 743721.Psesu_2457 4.6e-107 395.2 Xanthomonadales Bacteria 1PKJV@1224,1RW7J@1236,1XAHP@135614,COG1442@1,COG1442@2 NA|NA|NA M glycosyl transferase family 8 HFDCGJPN_02227 99598.Cal7507_5299 6e-83 314.3 Bacteria ko:K15257 ko00000,ko01000,ko03016 Bacteria COG0742@1,COG0742@2 NA|NA|NA L rRNA (guanine-N2-)-methyltransferase activity HFDCGJPN_02228 87626.PTD2_12104 2.3e-54 219.9 Pseudoalteromonadaceae hemG 1.3.3.15,1.3.3.4,1.4.3.4 ko:K00231,ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00860,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00860,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00121,M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R03222,R04025,R04178,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC00885,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 1R6WP@1224,1RZRE@1236,2Q2VG@267888,COG1232@1,COG1232@2 NA|NA|NA H NAD(P)-binding Rossmann-like domain HFDCGJPN_02229 309803.CTN_1920 1.5e-23 116.3 Thermotogae 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 2GCY7@200918,COG1045@1,COG1045@2 NA|NA|NA E Serine acetyltransferase HFDCGJPN_02232 1236959.BAMT01000011_gene3148 1.4e-26 125.6 Nitrosomonadales coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1MVQP@1224,2KM8M@206350,2VI4X@28216,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine HFDCGJPN_02233 582744.Msip34_0336 2.2e-73 281.6 Nitrosomonadales dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1RA7P@1224,2KMEE@206350,2VQ5I@28216,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA HFDCGJPN_02234 265072.Mfla_0312 1e-34 152.1 Nitrosomonadales rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1MZ57@1224,2KN2K@206350,2VU1B@28216,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family HFDCGJPN_02235 1101195.Meth11DRAFT_0403 3.6e-20 103.2 Nitrosomonadales rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1N6QV@1224,2KNAB@206350,2VVW8@28216,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family HFDCGJPN_02236 582744.Msip34_0333 7.5e-182 643.3 Betaproteobacteria desA 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 1N2MA@1224,2VHRS@28216,COG1398@1,COG1398@2 NA|NA|NA I fatty acid desaturase HFDCGJPN_02237 582744.Msip34_0332 7.7e-148 530.4 Nitrosomonadales aefA ko:K05802 ko00000,ko02000 1.A.23.1.1 Bacteria 1MWSA@1224,2KKZX@206350,2VJTH@28216,COG3264@1,COG3264@2 NA|NA|NA M PFAM MscS Mechanosensitive ion channel HFDCGJPN_02238 582744.Msip34_0331 1.5e-200 705.7 Nitrosomonadales mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 1MW24@1224,2KKRD@206350,2VI29@28216,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter HFDCGJPN_02239 582744.Msip34_0329 9.4e-57 226.1 Nitrosomonadales rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1RCWN@1224,2KMTV@206350,2VR6I@28216,COG0203@1,COG0203@2 NA|NA|NA J PFAM ribosomal protein L17 HFDCGJPN_02240 582744.Msip34_0328 1.1e-136 492.7 Nitrosomonadales rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1MU75@1224,2KKPA@206350,2VHG6@28216,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates HFDCGJPN_02243 582744.Msip34_1458 5.8e-37 159.8 Nitrosomonadales hupB ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1MZ5B@1224,2KN3N@206350,2VU4V@28216,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions HFDCGJPN_02244 1236959.BAMT01000001_gene1526 0.0 1374.0 Nitrosomonadales lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 1MUV2@1224,2KMG1@206350,2VIAU@28216,COG0466@1,COG0466@2 NA|NA|NA O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner HFDCGJPN_02245 1236959.BAMT01000001_gene1525 1.6e-217 761.9 Nitrosomonadales clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1MVQK@1224,2KKDJ@206350,2VIEU@28216,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP HFDCGJPN_02246 582744.Msip34_1461 3.6e-106 391.0 Nitrosomonadales clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1MV46@1224,2KM99@206350,2VHAZ@28216,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins HFDCGJPN_02247 582744.Msip34_1462 8.3e-182 643.3 Nitrosomonadales tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 ko:K03545 ko00000 Bacteria 1MUJP@1224,2KKU1@206350,2VING@28216,COG0544@1,COG0544@2 NA|NA|NA O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase HFDCGJPN_02249 1132855.KB913035_gene1246 3e-24 117.5 Nitrosomonadales Bacteria 1NCD5@1224,2CHG9@1,2KN9Q@206350,2VWRB@28216,3332K@2 NA|NA|NA HFDCGJPN_02250 582744.Msip34_1485 9.1e-115 420.6 Nitrosomonadales ko:K19123 ko00000,ko02048 Bacteria 1RFMJ@1224,2KMD4@206350,2W2GG@28216,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein HFDCGJPN_02251 1132855.KB913035_gene1244 2.1e-98 365.9 Nitrosomonadales Bacteria 1R6JG@1224,2KKVF@206350,2VUA5@28216,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family HFDCGJPN_02252 582744.Msip34_1487 0.0 1584.3 Nitrosomonadales cecA_2 ko:K11326 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1 Bacteria 1NUIV@1224,2KKBT@206350,2VHCZ@28216,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family HFDCGJPN_02253 582744.Msip34_1489 3.7e-53 214.2 Nitrosomonadales phhB 3.5.4.33,4.2.1.96 ko:K01724,ko:K11991 ko00790,map00790 R04734,R10223 RC00477,RC01208 ko00000,ko00001,ko01000,ko03016,ko04147 Bacteria 1RIEN@1224,2KMW0@206350,2VRX8@28216,COG2154@1,COG2154@2 NA|NA|NA H PFAM transcriptional coactivator pterin dehydratase HFDCGJPN_02254 582744.Msip34_1490 2.7e-66 258.5 Nitrosomonadales 1.13.11.81,2.7.4.31,4.1.2.25,5.1.99.8 ko:K01633,ko:K07144 ko00680,ko00790,ko01100,map00680,map00790,map01100 M00126,M00840 R03504,R11037,R11039,R11073 RC00002,RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1MZY4@1224,2KMVY@206350,2VRWS@28216,COG2054@1,COG2054@2 NA|NA|NA S PFAM aspartate glutamate uridylate kinase HFDCGJPN_02255 582744.Msip34_1491 1.4e-174 619.4 Nitrosomonadales pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 iEC042_1314.EC042_1977 Bacteria 1MVBJ@1224,2KM89@206350,2VP8B@28216,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I HFDCGJPN_02256 582744.Msip34_1492 1.1e-94 353.6 Nitrosomonadales 2.5.1.131 ko:K07072 ko00680,map00680 R11040 RC01372,RC03335 ko00000,ko00001,ko01000 Bacteria 1RAMA@1224,2KKXS@206350,2VKAE@28216,COG1548@1,COG1548@2 NA|NA|NA GK H4MPT-linked C1 transfer pathway protein HFDCGJPN_02257 265072.Mfla_1650 6.3e-56 224.6 Nitrosomonadales 6.3.4.24 ko:K06914 ko00680,map00680 R10902 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1RBY6@1224,2KMTW@206350,2VQ4F@28216,COG1821@1,COG1821@2 NA|NA|NA S ATP-grasp domain HFDCGJPN_02258 1236959.BAMT01000001_gene1489 4.3e-52 211.5 Nitrosomonadales 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1RHWE@1224,2KMS0@206350,2VTJW@28216,COG1411@1,COG1411@2 NA|NA|NA S Belongs to the HisA HisF family HFDCGJPN_02259 1101195.Meth11DRAFT_1505 3.1e-82 311.2 Nitrosomonadales fae 4.2.1.147 ko:K10713 ko00680,ko01120,ko01200,map00680,map01120,map01200 R08058 RC01583,RC01795 ko00000,ko00001,ko01000 Bacteria 1NDRY@1224,2KM2Y@206350,2VJ22@28216,COG1795@1,COG1795@2 NA|NA|NA S PFAM Formaldehyde-activating enzyme (Fae) HFDCGJPN_02260 582744.Msip34_1497 1.4e-82 312.4 Nitrosomonadales hxlB 4.1.2.14,4.1.2.43,4.1.3.42,5.3.1.27 ko:K01625,ko:K08094,ko:K13831 ko00030,ko00630,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00630,map00680,map01100,map01120,map01200,map01230 M00008,M00061,M00308,M00345,M00580,M00631 R00470,R05338,R05339,R05605,R09780 RC00307,RC00308,RC00377,RC00421,RC00422,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1RFKB@1224,2KMEB@206350,2W25Z@28216,COG0794@1,COG0794@2 NA|NA|NA M PFAM sugar isomerase (SIS) HFDCGJPN_02261 1502770.JQMG01000001_gene1123 3e-97 361.3 Nitrosomonadales rmpA 4.1.2.43,5.3.1.27 ko:K08093,ko:K13831 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338,R05339,R09780 RC00377,RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 Bacteria 1R970@1224,2KKJK@206350,2VWTN@28216,COG0269@1,COG0269@2 NA|NA|NA G PFAM Orotidine 5'-phosphate decarboxylase HFDCGJPN_02262 582744.Msip34_1499 2.7e-166 591.3 Nitrosomonadales tal GO:0003674,GO:0003824,GO:0004801,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 iYL1228.KPN_02798 Bacteria 1MWQ8@1224,2KKIE@206350,2VHIN@28216,COG0176@1,COG0176@2 NA|NA|NA G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway HFDCGJPN_02263 1236959.BAMT01000001_gene1483 1.3e-79 303.1 Nitrosomonadales citG 2.4.2.52,2.7.7.61 ko:K05964,ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1RAWI@1224,2KKD8@206350,2VQ7E@28216,COG1767@1,COG1767@2 NA|NA|NA H PFAM triphosphoribosyl-dephospho-CoA protein HFDCGJPN_02264 582744.Msip34_1501 1.8e-119 435.6 Nitrosomonadales rimK 6.3.1.17,6.3.2.32,6.3.2.41,6.3.2.43 ko:K05827,ko:K05844,ko:K14940,ko:K18310 ko00250,ko00300,ko00680,ko01100,ko01120,ko01210,ko01230,map00250,map00300,map00680,map01100,map01120,map01210,map01230 M00031 R09401,R09775,R10677,R10678 RC00064,RC00090,RC00141,RC03233 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1MX62@1224,2KKPT@206350,2VJZS@28216,COG0189@1,COG0189@2 NA|NA|NA HJ Belongs to the RimK family HFDCGJPN_02265 265072.Mfla_1658 7e-157 560.1 Nitrosomonadales mch GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704 3.5.4.27 ko:K01499 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03464 RC01870 ko00000,ko00001,ko00002,ko01000 Bacteria 1MUP6@1224,2KMGH@206350,2VMCD@28216,COG3252@1,COG3252@2 NA|NA|NA H Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT HFDCGJPN_02266 1165096.ARWF01000001_gene148 8.3e-68 264.2 Nitrosomonadales 3.5.4.27 ko:K01499,ko:K06913 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03464 RC01870 ko00000,ko00001,ko00002,ko01000 Bacteria 1R6Y7@1224,2KMYB@206350,2VQI8@28216,COG2232@1,COG2232@2 NA|NA|NA S ATP-grasp domain HFDCGJPN_02267 1236959.BAMT01000001_gene1478 6.4e-125 453.8 Nitrosomonadales hemA GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 ko:K02407,ko:K02492,ko:K10714,ko:K15671 ko00680,ko00860,ko01051,ko01052,ko01100,ko01110,ko01120,ko01200,ko02040,map00680,map00860,map01051,map01052,map01100,map01110,map01120,map01200,map02040 M00121 R04109,R08059 RC00055,RC00149,RC00202 ko00000,ko00001,ko00002,ko01000,ko01008,ko02035 iSB619.SA_RS08420 Bacteria 1MXX5@1224,2KM5G@206350,2VK09@28216,COG0373@1,COG0373@2 NA|NA|NA H Methylene-tetrahydromethanopterin dehydrogenase, N-terminal HFDCGJPN_02268 582744.Msip34_1505 2.3e-107 395.6 Nitrosomonadales mptG 2.4.2.54 ko:K06984 ko00790,map00790 R10337,R11102 ko00000,ko00001,ko01000 Bacteria 1MWHM@1224,2KKRY@206350,2VMEM@28216,COG1907@1,COG1907@2 NA|NA|NA S TIGRFAM beta-ribofuranosylaminobenzene 5'-phosphate synthase family HFDCGJPN_02269 1236959.BAMT01000002_gene2202 0.0 1312.0 Nitrosomonadales ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 Bacteria 1MU0R@1224,2KKSP@206350,2VHQ3@28216,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate HFDCGJPN_02270 1165096.ARWF01000001_gene144 8.4e-108 396.7 Nitrosomonadales ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1MUHU@1224,2KP6I@206350,2W0KQ@28216,COG1806@1,COG1806@2 NA|NA|NA S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation HFDCGJPN_02273 582744.Msip34_1457 1.2e-213 749.6 Nitrosomonadales ppiD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 ko:K01802,ko:K03769,ko:K03770 ko00000,ko01000,ko03110 Bacteria 1MWV0@1224,2KM3X@206350,2VJCZ@28216,COG0760@1,COG0760@2 NA|NA|NA O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase HFDCGJPN_02274 582744.Msip34_1456 2.8e-124 451.4 Nitrosomonadales fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0034641,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 iECUMN_1333.ECUMN_1592 Bacteria 1MV05@1224,2KKN5@206350,2VIHE@28216,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH HFDCGJPN_02275 265072.Mfla_1485 3.3e-123 448.0 Nitrosomonadales appC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MU26@1224,2KMEI@206350,2WESV@28216,COG1173@1,COG1173@2 NA|NA|NA EP PFAM binding-protein-dependent transport systems inner membrane component HFDCGJPN_02276 265072.Mfla_1484 2.9e-166 591.3 Nitrosomonadales oppB ko:K02033,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 1NS80@1224,2KKFQ@206350,2WH9T@28216,COG0601@1,COG0601@2 NA|NA|NA EP PFAM binding-protein-dependent transport systems inner membrane component HFDCGJPN_02277 582744.Msip34_1453 1.5e-257 895.2 Nitrosomonadales appA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1MUZH@1224,2KKDD@206350,2VMQS@28216,COG0747@1,COG0747@2 NA|NA|NA E PFAM extracellular solute-binding protein family 5 HFDCGJPN_02278 582744.Msip34_1452 6.8e-197 693.7 Nitrosomonadales mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 ko:K08307,ko:K12204 ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 1MWKE@1224,2KM60@206350,2VIR7@28216,COG0741@1,COG0741@2,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif HFDCGJPN_02279 582744.Msip34_1451 6.2e-73 280.8 Nitrosomonadales gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1MU8Q@1224,2KKV3@206350,2VGZG@28216,COG0491@1,COG0491@2 NA|NA|NA S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid HFDCGJPN_02280 1165096.ARWF01000001_gene183 4.9e-83 314.3 Nitrosomonadales yafS Bacteria 1QTWC@1224,2KMKA@206350,2VQ89@28216,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain HFDCGJPN_02281 1502770.JQMG01000001_gene1763 1.9e-66 258.5 Nitrosomonadales rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1RCZ1@1224,2KMT3@206350,2VR4W@28216,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids HFDCGJPN_02282 265072.Mfla_1478 2.3e-90 338.6 Nitrosomonadales dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1MV8Z@1224,2KKHK@206350,2VH1Z@28216,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease # 2080 queries scanned # Total time (seconds): 20.6617901325 # Rate: 100.67 q/s