CAZy_family Match_number Known_Activities Match_gene GT2 46 cellulose synthase (EC 2.4.1.12); chitin synthase (EC 2.4.1.16); dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83); dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117); N-acetylglucosaminyltransferase (EC 2.4.1.-); N-acetylgalactosaminyltransferase (EC 2.4.1.-); hyaluronan synthase (EC 2.4.1.212); chitin oligosaccharide synthase (EC 2.4.1.-); beta-1,3-glucan synthase (EC 2.4.1.34); beta-1,4-mannan synthase (EC 2.4.1.-); beta-mannosylphosphodecaprenol-mannooligosaccharide alpha-1,6-mannosyltransferase (EC 2.4.1.199); UDP-Galf: rhamnopyranosyl-N-acetylglucosaminyl-PP-decaprenol beta-1,4/1,5-galactofuranosyltransferase (EC 2.4.1.287); UDP-Galf: galactofuranosyl-galactofuranosyl-rhamnosyl-N-acetylglucosaminyl-PP-decaprenol beta-1,5/1,6-galactofuranosyltransferase (EC 2.4.1.288); dTDP-L-Rha: N-acetylglucosaminyl-PP-decaprenol alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.289); alternating beta-1,3/4-N-acetylmannan synthase (2.4.1.-) C2_00013, C2_00106, C2_00107, C2_00294, C2_00295, C2_00298, C2_00300, C2_00316, C2_00319, C2_00321, C2_00368, C2_00590, C2_00715, C2_00731, C2_00774, C2_01041, C2_01222, C2_01276, C2_01354, C2_01385, C2_01580, C2_02282, C2_02285, C2_02391, C2_02536, C2_02544, C2_02549, C2_02666, C2_02669, C2_02973, C2_02996, C2_03173, C2_03194, C2_03483, C2_03484, C2_03485, C2_03523, C2_03538, C2_03572, C2_03713, C2_03714, C2_03948, C2_04237, C2_04314, C2_04420, C2_04488 GT4 33 sucrose synthase (EC 2.4.1.13); sucrose-phosphate synthase (EC 2.4.1.14); alpha-glucosyltransferase (EC 2.4.1.52); lipopolysaccharide N-acetylglucosaminyltransferase (EC 2.4.1.56); phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57); GDP-Man: Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase (EC 2.4.1.132); GDP-Man: Man3GlcNAc2-PP-dolichol/Man4GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase (EC 2.4.1.131); digalactosyldiacylglycerol synthase (EC 2.4.1.141); 1,2-diacylglycerol 3-glucosyltransferase (EC 2.4.1.157); diglucosyl diacylglycerol synthase (EC 2.4.1.208); trehalose phosphorylase (EC 2.4.1.231); NDP-Glc: alpha-glucose alpha-glucosyltransferase / alpha,alpha-trehalose synthase (EC 2.4.1.245); GDP-Man: Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase (EC 2.4.1.257); UDP-GlcNAc: 2-deoxystreptamine alpha-N-acetylglucosaminyltransferase (EC 2.4.1.283); UDP-GlcNAc: ribostamycin alpha-N-acetylglucosaminyltransferase (EC 2.4.1.285); UDP-Gal alpha-galactosyltransferase (EC 2.4.1.-); UDP-Xyl alpha-xylosyltransferase (EC 2.4.2.-); UDP-GlcA alpha-glucuronyltransferase (EC 2.4.1.-); UDP-Glc alpha-glucosyltransferase (EC 2.4.1.-); UDP-GalNAc: GalNAc-PP-Und alpha-1,3-N-acetylgalactosaminyltransferase (EC 2.4.1.306); UDP-GalNAc: N,N'-diacetylbacillosaminyl-PP-Und alpha-1,3-N-acetylgalactosaminyltransferase (EC 2.4.1.290); ADP-dependent alpha-maltose-1-phosphate synthase (2.4.1.342) C2_00296, C2_00299, C2_00303, C2_00304, C2_00306, C2_00308, C2_00309, C2_00320, C2_00323, C2_00434, C2_00508, C2_00534, C2_01356, C2_01374, C2_01619, C2_01815, C2_01838, C2_01952, C2_02103, C2_02104, C2_02303, C2_02521, C2_02522, C2_02524, C2_02651, C2_02685, C2_02750, C2_03104, C2_03166, C2_03403, C2_03458, C2_03542, C2_03867 CBM50 27 Modules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below. C2_00146, C2_00182, C2_00223, C2_00430, C2_00798, C2_00802, C2_00857, C2_01003, C2_01047, C2_01501, C2_02074, C2_02214, C2_02299, C2_02359, C2_02538, C2_02545, C2_02875, C2_03056, C2_03221, C2_03279, C2_03534, C2_03556, C2_03965, C2_04157, C2_04176, C2_04238, C2_04565 GH23 19 lysozyme type G (EC 3.2.1.17); peptidoglycan lyase (EC 4.2.2.n1) also known in the literature as peptidoglycan lytic transglycosylase; chitinase (EC 3.2.1.14) C2_00179, C2_00481, C2_00487, C2_00488, C2_00507, C2_00709, C2_00974, C2_01204, C2_01623, C2_01724, C2_01840, C2_01928, C2_03099, C2_03668, C2_03674, C2_03685, C2_04019, C2_04030, C2_04036 GH1 14 beta-glucosidase (EC 3.2.1.21); beta-galactosidase (EC 3.2.1.23); beta-mannosidase (EC 3.2.1.25); beta-glucuronidase (EC 3.2.1.31); beta-xylosidase (EC 3.2.1.37); beta-D-fucosidase (EC 3.2.1.38); phlorizin hydrolase (EC 3.2.1.62); exo-beta-1,4-glucanase (EC 3.2.1.74); 6-phospho-beta-galactosidase (EC 3.2.1.85); 6-phospho-beta-glucosidase (EC 3.2.1.86); strictosidine beta-glucosidase (EC 3.2.1.105); lactase (EC 3.2.1.108); amygdalin beta-glucosidase (EC 3.2.1.117); prunasin beta-glucosidase (EC 3.2.1.118); vicianin hydrolase (EC 3.2.1.119); raucaffricine beta-glucosidase (EC 3.2.1.125); thioglucosidase (EC 3.2.1.147); beta-primeverosidase (EC 3.2.1.149); isoflavonoid 7-O-beta-apiosyl-beta-glucosidase (EC 3.2.1.161); ABA-specific beta-glucosidase (EC 3.2.1.175); DIMBOA beta-glucosidase (EC 3.2.1.182); beta-glycosidase (EC 3.2.1.-); hydroxyisourate hydrolase (EC 3.-.-.-); beta-rutinosidase /alpha-L-rhamnose-(1,6)-beta-D-glucosidase (EC 3.2.1.-) C2_00782, C2_01186, C2_01648, C2_02263, C2_02264, C2_02427, C2_02564, C2_02777, C2_03255, C2_03257, C2_04108, C2_04109, C2_04111, C2_04297 GH3 13 beta-glucosidase (EC 3.2.1.21); xylan 1,4-beta-xylosidase (EC 3.2.1.37); beta-glucosylceramidase (EC 3.2.1.45); beta-N-acetylhexosaminidase (EC 3.2.1.52); alpha-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,4-beta-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin beta-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); beta-N-acetylglucosaminide phosphorylases (EC 2.4.1.-); beta-1,2-glucosidase (EC 3.2.1.-); beta-1,3-glucosidase (EC 3.2.1.-); xyloglucan-specific exo-beta-1,4-glucanase / exo-xyloglucanase (EC 3.2.1.155) C2_00219, C2_00225, C2_00424, C2_00425, C2_00599, C2_01100, C2_01574, C2_02604, C2_02894, C2_03133, C2_03307, C2_03539, C2_04337 GH24 11 lysozyme (EC 3.2.1.17) C2_00690, C2_00691, C2_00714, C2_00953, C2_00955, C2_00966, C2_03843, C2_03844, C2_03914, C2_03915, C2_03964 GT9 10 lipopolysaccharide N-acetylglucosaminyltransferase (EC 2.4.1.56); heptosyltransferase (EC 2.4.-.-). C2_01894, C2_02169, C2_02191, C2_02520, C2_02529, C2_02531, C2_02532, C2_04368, C2_04434, C2_04559 GT51 8 murein polymerase (EC 2.4.1.129). C2_00133, C2_01540, C2_01584, C2_01685, C2_02626, C2_02891, C2_02938, C2_03573 GH2 8 beta-galactosidase (EC 3.2.1.23) ; beta-mannosidase (EC 3.2.1.25); beta-glucuronidase (EC 3.2.1.31); alpha-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-beta-mannosidase (EC 3.2.1.152); exo-beta-glucosaminidase (EC 3.2.1.165); alpha-L-arabinopyranosidase (EC 3.2.1.-); beta-galacturonidase (EC 3.2.1.-); beta-xylosidase (EC 3.2.1.37); beta-D-galactofuranosidase (EC 3.2.1.146); C2_00572, C2_00896, C2_00897, C2_01961, C2_01963, C2_03010, C2_03011, C2_03368 GH73 7 lysozyme (EC 3.2.1.17); mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity (EC 3.2.1.-) C2_00392, C2_00398, C2_00399, C2_00486, C2_02588, C2_03441, C2_04264 GT8 6 lipopolysaccharide alpha-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide alpha-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-alpha-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan alpha-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan alpha-glucuronyltransferase (EC 2.4.1.-); UDP-Gal:glucoside alpha-1,3-galactosyltransferase (EC 2.4.1.-) C2_01572, C2_02523, C2_02525, C2_02526, C2_02691, C2_03091 GH4 6 maltose-6-phosphate glucosidase (EC 3.2.1.122); alpha-glucosidase (EC 3.2.1.20); alpha-galactosidase (EC 3.2.1.22); 6-phospho-beta-glucosidase (EC 3.2.1.86); alpha-glucuronidase (EC 3.2.1.139); alpha-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-) C2_00580, C2_00776, C2_02465, C2_02466, C2_02467, C2_02823 GH0 5 Glycoside hydrolases not yet assigned to a family. C2_00059, C2_01425, C2_01590, C2_02207, C2_03862 CE4 5 acetyl xylan esterase (EC 3.1.1.72); chitin deacetylase (EC 3.5.1.41); chitooligosaccharide deacetylase (EC 3.5.1.-); peptidoglycan GlcNAc deacetylase (EC 3.5.1.-); peptidoglycan N-acetylmuramic acid deacetylase (EC 3.5.1.-). C2_01220, C2_01221, C2_01533, C2_01704, C2_02133 GH13 4 alpha-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-alpha-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); alpha-glucosidase (EC 3.2.1.20); maltotetraose-forming alpha-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming alpha-amylase (EC 3.2.1.98); maltotriose-forming alpha-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-alpha-glucanotransferase (EC 2.4.1.25); maltopentaose-forming alpha-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-alpha-1,6-glucosidase (EC 3.2.1.33); alpha-1,4-glucan: phosphate alpha-maltosyltransferase (EC 2.4.99.16); amino acid transporter; [retaining] sucrose 6(F)-phosphate phosphorylase (EC 2.4.1.329); [retaining] glucosylglycerol phosphorylase (EC 2.4.1.359); ; Glucosylglycerate phosphorylase (EC 2.4.1.352); [retaining] sucrose alpha-glucosidase (EC 3.2.1.48); oligosaccharide alpha-4-glucosyltransferase (EC 2.4.1.161) C2_00889, C2_01624, C2_02670, C2_02847 GH28 4 polygalacturonase (EC 3.2.1.15); exo-polygalacturonase (EC 3.2.1.67); exo-polygalacturonosidase (EC 3.2.1.82); rhamnogalacturonase (EC 3.2.1.171); rhamnogalacturonan alpha-1,2-galacturonohydrolase (EC 3.2.1.173); xylogalacturonan hydrolase (EC 3.2.1.-) C2_00792, C2_01634, C2_02502, C2_04415 GH103 4 peptidoglycan lytic transglycosylase (EC 3.2.1.-) C2_00051, C2_02249, C2_03381, C2_03382 GT35 4 glycogen or starch phosphorylase (EC 2.4.1.1). C2_00405, C2_00984, C2_02902, C2_02915 GT28 4 1,2-diacylglycerol 3-beta-galactosyltransferase (EC 2.4.1.46); 1,2-diacylglycerol 3-beta-glucosyltransferase (EC 2.4.1.157); UDP-GlcNAc: Und-PP-MurAc-pentapeptide beta-N-acetylglucosaminyltransferase (EC 2.4.1.227); digalactosyldiacylglycerol synthase (EC 2.4.1.241) C2_01741, C2_01742, C2_01743, C2_02248 GH65 4 alpha,alpha-trehalase (EC 3.2.1.28); maltose phosphorylase (EC 2.4.1.8); trehalose phosphorylase (EC 2.4.1.64); kojibiose phosphorylase (EC 2.4.1.230); trehalose-6-phosphate phosphorylase (EC 2.4.1.216); nigerose phosphorylase (EC 2.4.1.279); 3-O-alpha-glucopyranosyl-L-rhamnose phosphorylase (EC 2.4.1.282); 2-O-alpha-glucopyranosylglycerol: phosphate beta-glucosyltransferase (EC 2.4.1.-); alpha-glucosyl-1,2-beta-galactosyl-L-hydroxylysine alpha-glucosidase (EC 3.2.1.107); 1,3-α-oligoglucan phosphorylase (EC 2.4.1.334) C2_00629, C2_00631, C2_00632, C2_02060 CE9 4 N-acetylglucosamine 6-phosphate deacetylase (EC 3.5.1.25); N-acetylglucosamine 6-phosphate deacetylase (EC 3.5.1.80) C2_02699, C2_02799, C2_03789, C2_04338 CBM48 4 Modules of approx. 100 residues with glycogen-binding function, appended to GH13 modules. Also found in the beta subunit (glycogen-binding) of AMP-activated protein kinases (AMPK) C2_02430, C2_02898, C2_02899, C2_04326 GT19 3 lipid-A-disaccharide synthase (EC 2.4.1.182). C2_00651, C2_01652, C2_01653 GH47 3 alpha-mannosidase (EC 3.2.1.113) C2_02510, C2_02656, C2_03571 CE11 3 UDP-3-0-acyl N-acetylglucosamine deacetylase (EC 3.5.1.108). C2_01655, C2_01656, C2_01736 GT0 3 Glycosyltransferases not yet assigned to a family C2_02199, C2_03711, C2_04522 GT1 3 UDP-glucuronosyltransferase (EC 2.4.1.17); zeatin O-beta-xylosyltransferase (EC 2.4.2.40); 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.45); N-acylsphingosine galactosyltransferase (EC 2.4.1.47); flavonol 3-O-glucosyltransferase (EC 2.4.1.91); anthocyanidin 3-O-glucosyltransferase (EC 2.4.1.115); sinapate 1-glucosyltransferase (EC 2.4.1.120); indole-3-acetate beta-glucosyltransferase (EC 2.4.1.121); flavonol L-rhamnosyltransferase (EC 2.4.1.159); sterol glucosyltransferase (EC 2.4.1.173); UDP-Glc: 4-hydroxybenzoate 4-O-beta-glucosyltransferase (EC 2.4.1.194); zeatin O-beta-glucosyltransferase (EC 2.4.1.203); limonoid glucosyltransferase (EC 2.4.1.210); UDP-GlcA: baicalein 7-O-beta-glucuronosyltransferase (EC 2.4.1.253); UDP-Glc: chalcone 4'-O-beta-glucosyltransferase (EC 2.4.1.286); ecdysteroid UDP-glucosyltransferase (EC 2.4.1.-); salicylic acid beta-glucosyltransferase (EC 2.4.1.-); anthocyanin 3-O-galactosyltransferase (EC 2.4.1.-); anthocyanin 5-O-glucosyltransferase (EC 2.4.1.-); dTDP-beta-2-deoxy-L-fucose: alpha-L-2-deoxyfucosyltransferase (EC 2.4.1.-); UDP-beta-L-rhamnose: alpha-L-rhamnosyltransferase (EC 2.4.1.-); zeaxanthin glucosyltransferase (EC 2.4.1.-); flavone 8-C-glycosyltransferase; UDP-Glc: flavone-6-C-glucosytransferase (EC 2.4.1.-); UDP-Glc: cinnamate beta-glucosyltransferase (EC 2.4.1.177); UDP-Glc: hydroxycinnamic acid O-beta-glucosyltransferase (EC 2.4.1.-); UDP-Glc: cinnamoyl O-beta-glucosyltransferase (EC 2.4.1.-) C2_00862, C2_02234, C2_02999 CE0 3 See below. C2_00777, C2_01116, C2_04202 CE8 3 pectin methylesterase (EC 3.1.1.11). C2_03503, C2_03525, C2_04334 GT83 3 undecaprenyl phosphate-alpha-L-Ara4N: 4-amino-4-deoxy-beta-L-arabinosyltransferase (EC 2.4.2.43); dodecaprenyl phosphate-beta-galacturonic acid: lipopolysaccharide core alpha-galacturonosyl transferase (EC 2.4.1.-) C2_00103, C2_00105, C2_02084 GT87 3 polyprenol-P-Man: alpha-1,2-mannosyltransferase (EC 2.4.1.-) C2_00751, C2_01818, C2_03576 GH78 2 alpha-L-rhamnosidase (EC 3.2.1.40); rhamnogalacturonan alpha-L-rhamnohydrolase (EC 3.2.1.174); L-Rhap-alpha-1,3-D-Apif -specific alpha-1,3-L-rhamnosidase (EC 3.2.1.-) C2_00364, C2_01527 GT22 2 Dol-P-Man: Man6GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.259); Dol-P-Man: Man8GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.261); Dol-P-Man: Man2-GlcNAc-phosphatidylinositol alpha-1,2-mannosyltransferase (EC 2.4.1.-); Dol-P-Man: Man3-GlcNAc-phosphatidylinositol alpha-1,2-mannosyltransferase (EC 2.4.1.-) C2_03121, C2_03569 GH76 2 alpha-1,6-mannanase (EC 3.2.1.101); alpha-glucosidase (EC 3.2.1.20) C2_03356, C2_04454 GH38 2 alpha-mannosidase (EC 3.2.1.24); mannosyl-oligosaccharide alpha-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide alpha-1,3-1,6-mannosidase (EC 3.2.1.114); alpha-2-O-mannosylglycerate hydrolase (EC 3.2.1.170); mannosyl-oligosaccharide alpha-1,3-mannosidase (EC 3.2.1.-) C2_03566, C2_04269 GH18 2 chitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-beta-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin C2_01089, C2_03706 GH37 2 alpha,alpha-trehalase (EC 3.2.1.28). C2_00492, C2_03498 GH36 2 alpha-galactosidase (EC 3.2.1.22); alpha-N-acetylgalactosaminidase (EC 3.2.1.49); stachyose synthase (EC 2.4.1.67); raffinose synthase (EC 2.4.1.82) C2_02907, C2_03012 GH92 2 mannosyl-oligosaccharide alpha-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide alpha-1,3-mannosidase (EC 3.2.1.-); mannosyl-oligosaccharide alpha-1,6-mannosidase (EC 3.2.1.-); alpha-mannosidase (EC 3.2.1.24); alpha-1,2-mannosidase (EC 3.2.1.-); alpha-1,3-mannosidase (EC 3.2.1.-); alpha-1,4-mannosidase (EC 3.2.1.-); mannosyl-1-phosphodiester alpha-1,P-mannosidase (EC 3.2.1.-) C2_02883, C2_04435 AA3_2 2 C2_01594, C2_03047 GT26 2 UDP-ManNAcA: beta-N-acetyl mannosaminuronyltransferase (EC 2.4.1.-); UDP-ManNAc: beta-N-acetyl-mannosaminyltransferase (EC 2.4.1.-); UDP-Glc: beta-1,4-glucosyltransferase (EC 2.4.1.-); beta-1,4-galactosyltransferase (EC 2.4.1.-) C2_01794, C2_03720 GT32 2 alpha-1,6-mannosyltransferase (EC 2.4.1.-); alpha-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.-); alpha-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); GDP-Man: inositol-phosphorylceramide transferase (EC 2.4.1.-); UDP-Gal: beta-galactoside alpha-1,4-galactosyltransferase (EC 2.4.1.-); UDP-Gal: lactose/N-acetyl-lactosamine alpha-1,4-galactosyltransferase (EC 2.4.1.-); UDP-Glc: protein alpha-glucosyltransferase (EC 2.4.1.-) C2_00317, C2_04382 GT30 2 CMP-beta-KDO: alpha-3-deoxy-D-manno-octulosonic-acid (KDO) transferase (EC 2.4.99.-). C2_00322, C2_02519 CE14 2 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (EC 3.5.1.89); diacetylchitobiose deacetylase (EC 3.5.1.-); mycothiol S-conjugate amidase (EC 3.5.1.-) C2_01004, C2_02995 CBM6 2 Modules of approx. 120 residues. The cellulose-binding function has been demonstrated in one case on amorphous cellulose and beta-1,4-xylan. Some of these modules also bind beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan. C2_00933, C2_00971 GH13_31 2 C2_01563, C2_02321 GH108 2 N-acetylmuramidase (EC 3.2.1.17) C2_01371, C2_04605 GT56 2 TDP-Fuc4NAc: lipid II Fuc4NAc transferase (EC 2.4.1.-) C2_03718, C2_03719 GH13_11 2 C2_01616, C2_02900 CBM13 2 Modules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis. C2_02069, C2_04549 GH13_18 2 C2_00623, C2_01893 GH13_29 2 C2_01073, C2_01074 CE12 2 pectin acetylesterase (EC 3.1.1.-); rhamnogalacturonan acetylesterase (EC 3.1.1.-); acetyl xylan esterase (EC 3.1.1.72) C2_01892, C2_02386 PL1_1 1 C2_00287 GH77 1 amylomaltase or 4-alpha-glucanotransferase (EC 2.4.1.25) C2_02916 PL22_1 1 C2_00645 GH8 1 chitosanase (EC 3.2.1.132); cellulase (EC 3.2.1.4); licheninase (EC 3.2.1.73); endo-1,4-beta-xylanase (EC 3.2.1.8); reducing-end-xylose releasing exo-oligoxylanase (EC 3.2.1.156) C2_03486 PL35 1 chondroitin lyase / chondroitinase (EC 4.2.2.-); chondroitin AC lyase (EC 4.2.2.5) C2_00996 GT80 1 beta-galactoside alpha-2,6-sialyltransferase (EC 2.4.99.1); beta-galactoside alpha-2,3-sialyltransferase (EC 2.4.99.4) C2_02424 GH85 1 endo-beta-N-acetylglucosaminidase (EC 3.2.1.96) C2_02399 GH72 1 beta-1,3-glucanosyltransglycosylase (EC 2.4.1.-) C2_00499 GH67 1 alpha-glucuronidase (EC 3.2.1.139); xylan alpha-1,2-glucuronidase (EC 3.2.1.131) C2_01131 GT73 1 CMP-beta-KDO: alpha-3-deoxy-D-manno-octulosonic-acid (KDO) transferase (EC 2.4.99.-). C2_02528 GH9 1 endoglucanase (EC 3.2.1.4); endo-beta-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6); beta-glucosidase (EC 3.2.1.21); lichenase / endo-beta-1,3-1,4-glucanase (EC 3.2.1.73); exo-beta-1,4-glucanase / cellodextrinase (EC 3.2.1.74); cellobiohydrolase (EC 3.2.1.91); xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); exo-beta-glucosaminidase (EC 3.2.1.165); endo-beta-1,4-glucanase (xanthanase) (EC 3.2.1.-) C2_03148 GT77 1 alpha-xylosyltransferase (EC 2.4.2.39); alpha-1,3-galactosyltransferase (EC 2.4.1.37); arabinosyltransferase (EC 2.4.2.-); arabinosyltransferase (EC 2.4.2.-) C2_04360 GT66 1 dolichyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.99.18); undecaprenyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.99.19) C2_02970 GT58 1 Dol-P-Man: Man5GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase (EC 2.4.1.258) C2_02412 GT5 1 UDP-Glc: glycogen glucosyltransferase (EC 2.4.1.11); ADP-Glc: starch glucosyltransferase (EC 2.4.1.21); NDP-Glc: starch glucosyltransferase (EC 2.4.1.242); UDP-Glc: alpha-1,3-glucan synthase (EC 2.4.1.183) UDP-Glc: alpha-1,4-glucan synthase (EC 2.4.1.-) C2_02901 GT106 1 UDP-beta-L-rhamnose:rhamnogalacturonan I 4-alpha-rhamnosyltransferase (EC 2.4.1.351) C2_03209 GT47 1 heparan beta-glucuronyltransferase (EC 2.4.1.225); xyloglucan beta-galactosyltransferase (EC 2.4.1.-); heparan synthase (EC 2.4.1.-); arabinan alpha-L-arabinosyltransferase (EC 2.4.2.-). C2_01011 GT107 1 CMP-beta-KDO: beta-2,4-KDO transferase (EC 2.4.99.-); CMP-beta-KDO: beta-2,7-KDO transferase (EC 2.4.99.-) C2_00456 GT17 1 beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.144). C2_03190 GH63 1 processing alpha-glucosidase (EC 3.2.1.106); alpha-1,3-glucosidase (EC 3.2.1.84); alpha-glucosidase (EC 3.2.1.20); mannosylglycerate alpha-mannosidase / mannosylglycerate hydrolase (EC 3.2.1.170); glucosylglycerate hydrolase (EC 3.2.1.208) C2_01965 GT20 1 alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15); Glucosylglycerol-phosphate synthase (EC 2.4.1.213); trehalose-6-P phosphatase (EC 3.1.3.12); [retaining] GDP-valeniol: validamine 7-phosphate valeniolyltransferase (EC 2.-.-.-) C2_02112 GT31 1 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149); Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase (EC 2.4.1.122); fucose-specific beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.-); globotriosylceramide beta-1,3-GalNAc transferase (EC 2.4.1.79); chondroitin synthase (beta-1,3-GlcUA and beta-1,4-GalNAc transferase (EC 2.4.1.175); chondroitin beta-1,3-glucuronyltransferase (EC 2.4.1.226); chondroitin beta-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); UDP-Gal: beta-galactosylxylosylprotein beta-1,3-galactosyltransferase (EC 2.4.1.134); UDP-GlcNAc: O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.222) C2_03802 AA0 1 C2_04539 GH33 1 sialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-) C2_03184 GH6 1 endoglucanase (EC 3.2.1.4); cellobiohydrolase (EC 3.2.1.91); lichenase / endo-beta-1,3-1,4-glucanase (EC 3.2.1.73); lichenase / endo-beta-1,3-1,4-glucanase (EC 3.2.1.73); C2_04252 GH13_39 1 C2_01999 GH13_26 1 C2_03389 GH13_23 1 C2_04316 GH13_19 1 C2_03440 GH13_16 1 C2_01605 GH135 1 alpha-1,4-galactosaminogalactan hydrolase (EC 3.2.1.-) C2_02405 GH130 1 beta-1,4-mannosylglucose phosphorylase (EC 2.4.1.281); beta-1,4-mannooligosaccharide phosphorylase (EC 2.4.1.319); beta-1,4-mannosyl-N-acetyl-glucosamine phosphorylase (EC 2.4.1.320); beta-1,2-mannobiose phosphorylase (EC 2.4.1.-); beta-1,2-oligomannan phosphorylase (EC 2.4.1.-); beta-1,2-mannosidase (EC 3.2.1.-) C2_00533 GH125 1 exo-alpha-1,6-mannosidase (EC 3.2.1.-) C2_02869 GH12 1 endoglucanase (EC 3.2.1.4); xyloglucan hydrolase (EC 3.2.1.151); beta-1,3-1,4-glucanase (EC 3.2.1.73); xyloglucan endotransglycosylase (EC 2.4.1.207) C2_01330 GH109 1 alpha-N-acetylgalactosaminidase (EC 3.2.1.49) C2_02840 GH102 1 peptidoglycan lytic transglycosylase (EC 3.2.1.-) C2_02355 GH100 1 alkaline and neutral invertase (EC 3.2.1.26) C2_02385 GH10 1 endo-1,4-beta-xylanase (EC 3.2.1.8); endo-1,3-beta-xylanase (EC 3.2.1.32); tomatinase (EC 3.2.1.-); xylan endotransglycosylase (EC 2.4.2.-); endo-beta-1,4-glucanase (EC 3.2.1.4) C2_01208 CBM5 1 Modules of approx. 60 residues found in bacterial enzymes. Chitin-binding described in several cases. Distantly related to the CBM12 family. C2_04556 CBM34 1 Modules of approx. 120 residues. Granular starch-binding function has been demonstrated in the case of Thermoactinomyces vulgaris R-47 alpha-amylase 1 (TVAI). C2_03136 CBM2 1 Modules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan. C2_00391 CBM14 1 Modules of approx. 70 residues. The chitin-binding function has been demonstrated in several cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats; chitin binding (EC IIa.chitin) C2_01598 CBM10 1 Modules of approx. 50 residues. The cellulose-binding function has been demonstrated in one case. C2_00657 AA6 1 1,4-benzoquinone reductase (EC. 1.6.5.6) C2_01240 AA5_1 1 C2_03522 GH13_3 1 C2_01042 GH13_5 1 C2_02142 GH5_18 1 C2_02398 GH140 1 beta-1,2-apiosidase (EC 3.2.1.-) C2_02426 GH58 1 endo-N-acetylneuraminidase or endo-sialidase (EC 3.2.1.129) C2_03905 GH57 1 alpha-amylase (EC 3.2.1.1); alpha-galactosidase (EC 3.2.1.22); amylopullulanase (EC 3.2.1.41); cyclomaltodextrinase (EC 3.2.1.54); branching enzyme (EC 2.4.1.18); 4-alpha-glucanotransferase (EC 2.4.1.25) C2_00409 GH55 1 exo-beta-1,3-glucanase (EC 3.2.1.58); endo-beta-1,3-glucanase (EC 3.2.1.39) C2_03400 GH51 1 endoglucanase (EC 3.2.1.4); endo-beta-1,4-xylanase (EC 3.2.1.8); beta-xylosidase (EC 3.2.1.37); alpha-L-arabinofuranosidase (EC 3.2.1.55); lichenase / endo-beta-1,3-1,4-glucanase (EC 3.2.1.73) C2_03907 GH43_26 1 C2_02494 GH43_12 1 C2_00932 GH43_11 1 C2_02882 GH39 1 alpha-L-iduronidase (EC 3.2.1.76); beta-xylosidase (EC 3.2.1.37); alpha-L-arabinofuranosidase (EC 3.2.1.55); beta-glucosidase (EC 3.2.1.21); beta-galactosidase (EC 3.2.1.23) C2_02721 GH35 1 beta-galactosidase (EC 3.2.1.23); exo-beta-glucosaminidase (EC 3.2.1.165); exo-beta-1,4-galactanase (EC 3.2.1.-); beta-1,3-galactosidase (EC 3.2.1.-) C2_03353 GH31 1 alpha-glucosidase (EC 3.2.1.20); alpha-galactosidase (EC 3.2.1.22); alpha-mannosidase (EC 3.2.1.24); alpha-1,3-glucosidase (EC 3.2.1.84); sucrase-isomaltase (EC 3.2.1.48) (EC 3.2.1.10); alpha-xylosidase (EC 3.2.1.177); alpha-glucan lyase (EC 4.2.2.13); isomaltosyltransferase (EC 2.4.1.-); oligosaccharide alpha-1,4-glucosyltransferase (EC 2.4.1.161); sulfoquinovosidase (EC 3.2.1.-); alpha-N-acetylgalactosaminidase (EC 3.2.1.49); ; sulfoquinovosidase (EC 3.2.1.199) C2_02495 GH27 1 alpha-galactosidase (EC 3.2.1.22); alpha-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); beta-L-arabinopyranosidase (EC 3.2.1.88); galactan:galactan galactosyltransferase (EC 2.4.1.-) C2_03803 GH25 1 lysozyme (EC 3.2.1.17) C2_00255 GH20 1 beta-hexosaminidase (EC 3.2.1.52); lacto-N-biosidase (EC 3.2.1.140); beta-1,6-N-acetylglucosaminidase (EC 3.2.1.-); beta-6-SO3-N-acetylglucosaminidase (EC 3.2.1.-) C2_02867 GH19 1 chitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17) C2_04558 GH170 1 C2_01494 GH17 1 glucan endo-1,3-beta-glucosidase (EC 3.2.1.39); licheninase (EC 3.2.1.73); ABA-specific beta-glucosidase (EC 3.2.1.175); beta-1,3-glucanosyltransglycosylase (EC 2.4.1.-); beta-1,3-glucosidase (EC 3.2.1.-) C2_01245 GH16_27 1 C2_03147 GH16 1 xyloglucan:xyloglucosyltransferase (EC 2.4.1.207); keratan-sulfate endo-1,4-beta-galactosidase (EC 3.2.1.103); endo-1,3-beta-glucanase / laminarinase (EC 3.2.1.39); endo-1,3(4)-beta-glucanase (EC 3.2.1.6); licheninase (EC 3.2.1.73); beta-agarase (EC 3.2.1.81); kappa;-carrageenase (EC 3.2.1.83); xyloglucanase (EC 3.2.1.151); endo-beta-1,3-galactanase (EC 3.2.1.181); [retaining] beta-porphyranase (EC 3.2.1.178); hyaluronidase (EC 3.2.1.35); endo-beta-1,4-galactosidase (EC 3.2.1.-); chitin beta-1,6-glucanosyltransferase (EC 2.4.1.-); beta-transglycosidase (EC 2.4.1.-); beta-glycosidase (EC 3.2.1.-); beta-carrageenase (EC 3.2.1.-) C2_00880 GH152 1 beta-1,3-glucanase (EC 3.2.1.39) C2_02039 PL4_2 1 C2_03028